BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1294 Length=441 Score E Sequences producing significant alignments: (Bits) Value gi|15608434|ref|NP_215810.1| homoserine dehydrogenase [Mycobacte... 860 0.0 gi|289761449|ref|ZP_06520827.1| homoserine dehydrogenase thrA [M... 856 0.0 gi|240169520|ref|ZP_04748179.1| homoserine dehydrogenase [Mycoba... 776 0.0 gi|183984074|ref|YP_001852365.1| homoserine dehydrogenase ThrA [... 767 0.0 gi|118619174|ref|YP_907506.1| homoserine dehydrogenase [Mycobact... 761 0.0 gi|118464687|ref|YP_880748.1| homoserine dehydrogenase [Mycobact... 761 0.0 gi|342858045|ref|ZP_08714701.1| homoserine dehydrogenase [Mycoba... 760 0.0 gi|41408566|ref|NP_961402.1| homoserine dehydrogenase [Mycobacte... 759 0.0 gi|254821293|ref|ZP_05226294.1| homoserine dehydrogenase [Mycoba... 754 0.0 gi|296170235|ref|ZP_06851828.1| homoserine dehydrogenase [Mycoba... 745 0.0 gi|15827560|ref|NP_301823.1| homoserine dehydrogenase [Mycobacte... 740 0.0 gi|126436458|ref|YP_001072149.1| homoserine dehydrogenase [Mycob... 723 0.0 gi|118473179|ref|YP_889209.1| homoserine dehydrogenase [Mycobact... 721 0.0 gi|108800860|ref|YP_641057.1| homoserine dehydrogenase [Mycobact... 721 0.0 gi|120405302|ref|YP_955131.1| homoserine dehydrogenase [Mycobact... 694 0.0 gi|145222886|ref|YP_001133564.1| homoserine dehydrogenase [Mycob... 681 0.0 gi|315443351|ref|YP_004076230.1| homoserine dehydrogenase [Mycob... 680 0.0 gi|333989933|ref|YP_004522547.1| homoserine dehydrogenase [Mycob... 661 0.0 gi|169628526|ref|YP_001702175.1| homoserine dehydrogenase [Mycob... 660 0.0 gi|4894690|gb|AAD32592.1|AF126720_3 homoserine dehydrogenase [My... 622 3e-176 gi|226307409|ref|YP_002767369.1| homoserine dehydrogenase [Rhodo... 612 5e-173 gi|226360612|ref|YP_002778390.1| homoserine dehydrogenase [Rhodo... 607 1e-171 gi|111018489|ref|YP_701461.1| homoserine dehydrogenase [Rhodococ... 605 6e-171 gi|312139161|ref|YP_004006497.1| homoserine dehydrogenase thra [... 591 9e-167 gi|262201841|ref|YP_003273049.1| homoserine dehydrogenase [Gordo... 590 2e-166 gi|326382076|ref|ZP_08203769.1| homoserine dehydrogenase [Gordon... 583 3e-164 gi|343928052|ref|ZP_08767517.1| homoserine dehydrogenase [Gordon... 573 2e-161 gi|54023016|ref|YP_117258.1| homoserine dehydrogenase [Nocardia ... 550 2e-154 gi|296138957|ref|YP_003646200.1| homoserine dehydrogenase [Tsuka... 543 3e-152 gi|333920934|ref|YP_004494515.1| Homoserine dehydrogenase [Amyco... 540 2e-151 gi|319948888|ref|ZP_08023000.1| homoserine dehydrogenase [Dietzi... 535 9e-150 gi|257056969|ref|YP_003134801.1| homoserine dehydrogenase [Sacch... 519 4e-145 gi|229490020|ref|ZP_04383873.1| homoserine dehydrogenase [Rhodoc... 515 7e-144 gi|254231552|ref|ZP_04924879.1| homoserine dehydrogenase thrA [M... 511 8e-143 gi|302529807|ref|ZP_07282149.1| homoserine dehydrogenase [Strept... 509 2e-142 gi|256380149|ref|YP_003103809.1| homoserine dehydrogenase [Actin... 504 1e-140 gi|300789614|ref|YP_003769905.1| homoserine dehydrogenase [Amyco... 502 4e-140 gi|337768157|emb|CCB76870.1| Homoserine dehydrogenase [Streptomy... 494 1e-137 gi|290957372|ref|YP_003488554.1| homoserine dehydrogenase [Strep... 489 3e-136 gi|325002814|ref|ZP_08123926.1| homoserine dehydrogenase [Pseudo... 486 2e-135 gi|254387530|ref|ZP_05002769.1| homoserine dehydrogenase [Strept... 486 3e-135 gi|294815082|ref|ZP_06773725.1| Homoserine dehydrogenase [Strept... 486 3e-135 gi|296393111|ref|YP_003657995.1| homoserine dehydrogenase [Segni... 485 6e-135 gi|329939820|ref|ZP_08289121.1| homoserine dehydrogenase [Strept... 484 1e-134 gi|19552407|ref|NP_600409.1| homoserine dehydrogenase [Corynebac... 483 3e-134 gi|302554158|ref|ZP_07306500.1| homoserine dehydrogenase [Strept... 482 5e-134 gi|291437227|ref|ZP_06576617.1| homoserine dehydrogenase [Strept... 481 1e-133 gi|317506160|ref|ZP_07963982.1| homoserine dehydrogenase [Segnil... 481 1e-133 gi|331695514|ref|YP_004331753.1| homoserine dehydrogenase [Pseud... 480 2e-133 gi|325295761|gb|ADZ04937.1| homoserine dehydrogenase [Corynebact... 480 2e-133 >gi|15608434|ref|NP_215810.1| homoserine dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15840744|ref|NP_335781.1| homoserine dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31792487|ref|NP_854980.1| homoserine dehydrogenase [Mycobacterium bovis AF2122/97] 76 more sequence titles Length=441 Score = 860 bits (2221), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/441 (99%), Positives = 441/441 (100%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +PGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE Sbjct 1 MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA Sbjct 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS Sbjct 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR Sbjct 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA Sbjct 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 LDDLDVVQGVSSVIRLEGTGL Sbjct 421 LDDLDVVQGVSSVIRLEGTGL 441 >gi|289761449|ref|ZP_06520827.1| homoserine dehydrogenase thrA [Mycobacterium tuberculosis GM 1503] gi|289708955|gb|EFD72971.1| homoserine dehydrogenase thrA [Mycobacterium tuberculosis GM 1503] Length=441 Score = 856 bits (2211), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/441 (99%), Positives = 440/441 (99%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +PGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE Sbjct 1 MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA Sbjct 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS Sbjct 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR Sbjct 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMG IETRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGSIETRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA Sbjct 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 LDDLDVVQGVSSVIRLEGTGL Sbjct 421 LDDLDVVQGVSSVIRLEGTGL 441 >gi|240169520|ref|ZP_04748179.1| homoserine dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=441 Score = 776 bits (2003), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/441 (92%), Positives = 423/441 (96%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +PGDEKPVGVAVLGLGNVGSEVVRIIE SA+DLAARVGAPLVLRG+GVRRV DRGVP+E Sbjct 1 MPGDEKPVGVAVLGLGNVGSEVVRIIEESADDLAARVGAPLVLRGVGVRRVAPDRGVPVE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTD+IEELV+REDVDIVVEVMGPVEPSRKAIL ALE GKS+VTANKALL+TSTGELAQA Sbjct 61 LLTDNIEELVSREDVDIVVEVMGPVEPSRKAILTALEHGKSIVTANKALLSTSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY S Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYES 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRV ADDVYREGITKVTPADF + Sbjct 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVHADDVYREGITKVTPADFET 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 AHALGCTIKLLSICERIT D+G QRVSARVYPALVPL+HPLA VNGAFNAVVVEAEAAGR Sbjct 241 AHALGCTIKLLSICERITDDDGQQRVSARVYPALVPLTHPLATVNGAFNAVVVEAEAAGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLP+APMG I TRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPIAPMGLISTRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS+VAAEFAK +VSIAEVRQEGV DEGG+RVGARIVVVTHLATDAALS+TV A Sbjct 361 VADKPGVLSSVAAEFAKHDVSIAEVRQEGVADEGGKRVGARIVVVTHLATDAALSKTVAA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 L DLDVVQ V+SV+RLEGTGL Sbjct 421 LADLDVVQDVTSVLRLEGTGL 441 >gi|183984074|ref|YP_001852365.1| homoserine dehydrogenase ThrA [Mycobacterium marinum M] gi|183177400|gb|ACC42510.1| homoserine dehydrogenase ThrA [Mycobacterium marinum M] Length=441 Score = 767 bits (1980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/439 (92%), Positives = 419/439 (96%), Gaps = 0/439 (0%) Query 3 GDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELL 62 GD KPVGVAVLGLGNVGSEVVRIIE SA+DLAARVGAPLVLRG+GVRRV DRGVPI+LL Sbjct 3 GDVKPVGVAVLGLGNVGSEVVRIIEESADDLAARVGAPLVLRGVGVRRVADDRGVPIDLL 62 Query 63 TDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAE 122 TDDIE+LV+REDVDIVVEVMGPVEPSRKAIL ALE GKSVVTANKALL+TSTGELAQAAE Sbjct 63 TDDIEKLVSREDVDIVVEVMGPVEPSRKAILTALEHGKSVVTANKALLSTSTGELAQAAE 122 Query 123 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASAL 182 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYA AL Sbjct 123 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYAKAL 182 Query 183 ADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAH 242 ADA ALGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITK+TPADF SA Sbjct 183 ADAGALGYAEADPTADVEGFDAAAKAAILASIAFHTRVTADDVYREGITKITPADFASAR 242 Query 243 ALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLM 302 ALGCTIKLLSICER+TTDEG QRVSARVYPALVPLSHPLA VNGAFNAVVVEAEAAGRLM Sbjct 243 ALGCTIKLLSICERLTTDEGQQRVSARVYPALVPLSHPLATVNGAFNAVVVEAEAAGRLM 302 Query 303 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVA 362 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFI TRYYVSMNVA Sbjct 303 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFISTRYYVSMNVA 362 Query 363 DKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALD 422 DK GVLSAVAAEFAKR+VSIAEVRQEGVVD+ G+R+GARIVVVTHLATDAALSETV+AL Sbjct 363 DKAGVLSAVAAEFAKRDVSIAEVRQEGVVDQDGQRIGARIVVVTHLATDAALSETVEALA 422 Query 423 DLDVVQGVSSVIRLEGTGL 441 DLDVV+ V+SV+RLEG L Sbjct 423 DLDVVENVASVLRLEGNDL 441 >gi|118619174|ref|YP_907506.1| homoserine dehydrogenase [Mycobacterium ulcerans Agy99] gi|118571284|gb|ABL06035.1| homoserine dehydrogenase ThrA [Mycobacterium ulcerans Agy99] Length=441 Score = 761 bits (1966), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/439 (91%), Positives = 418/439 (96%), Gaps = 0/439 (0%) Query 3 GDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELL 62 GD KPVGVAVLGLGNVGSEVVRIIE SA+DLAARVGAPLVLRG+GVRRV DRGVPI+LL Sbjct 3 GDVKPVGVAVLGLGNVGSEVVRIIEESADDLAARVGAPLVLRGVGVRRVADDRGVPIDLL 62 Query 63 TDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAE 122 TDDIE+LV+REDVDIVVEVMGPVEPSRKAIL ALE GKSVVTANKALL+TSTGELAQAAE Sbjct 63 TDDIEKLVSREDVDIVVEVMGPVEPSRKAILTALEHGKSVVTANKALLSTSTGELAQAAE 122 Query 123 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASAL 182 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYA AL Sbjct 123 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYAKAL 182 Query 183 ADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAH 242 ADA ALGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITK+TPADF SA Sbjct 183 ADAGALGYAEADPTADVEGFDAAAKAAILASIAFHTRVTADDVYREGITKITPADFASAR 242 Query 243 ALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLM 302 ALGCTIKLLSICER+TTDEG QRVSARVYPALVPLSHPLA VNGAFNAVVVEAEAAGRLM Sbjct 243 ALGCTIKLLSICERLTTDEGQQRVSARVYPALVPLSHPLATVNGAFNAVVVEAEAAGRLM 302 Query 303 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVA 362 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFI TRYYVS+NVA Sbjct 303 FYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFISTRYYVSINVA 362 Query 363 DKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALD 422 DK GVLSAVAAEFAKR+VSIAEVRQ+GVVD+ G+R+GARIVVVTHLATDAALSETV+ L Sbjct 363 DKAGVLSAVAAEFAKRDVSIAEVRQKGVVDQDGQRIGARIVVVTHLATDAALSETVEVLA 422 Query 423 DLDVVQGVSSVIRLEGTGL 441 DLDVV+ V+SV+RLEG L Sbjct 423 DLDVVENVASVLRLEGNDL 441 >gi|118464687|ref|YP_880748.1| homoserine dehydrogenase [Mycobacterium avium 104] gi|254774333|ref|ZP_05215849.1| homoserine dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] gi|118165974|gb|ABK66871.1| homoserine dehydrogenase [Mycobacterium avium 104] gi|336460915|gb|EGO39798.1| homoserine dehydrogenase [Mycobacterium avium subsp. paratuberculosis S397] Length=441 Score = 761 bits (1965), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/441 (91%), Positives = 417/441 (95%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +P DEKPVGVAVLGLGNVGSEVVRIIE+SA DLAAR+GAPLVLRG+GVRRV DRGVP+E Sbjct 1 MPRDEKPVGVAVLGLGNVGSEVVRIIEDSAGDLAARIGAPLVLRGVGVRRVADDRGVPVE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIE L AR+DVDIVVE+MGPVEPSRKAIL ALE GKSVVTANKALL+TSTGELAQA Sbjct 61 LLTDDIEGLAARDDVDIVVELMGPVEPSRKAILCALEHGKSVVTANKALLSTSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY + Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDT 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALA+AS LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITK+TPADF S Sbjct 181 ALAEASDLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKITPADFAS 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A ALGCTIKLLSICERIT D+G +RVSARVYPALVPLSHPLA VNGAFNAVVVEA A+GR Sbjct 241 ARALGCTIKLLSICERITGDDGQERVSARVYPALVPLSHPLATVNGAFNAVVVEARASGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAV GDLVMAARNRVLGSRGPRESKYAQLPVAPMGFI TRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVAGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFISTRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS+VAAEFAKREVSIAEVRQEGV DEGGRRVGARIVVVTH ATDAALSETV A Sbjct 361 VADKPGVLSSVAAEFAKREVSIAEVRQEGVADEGGRRVGARIVVVTHTATDAALSETVHA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 L DLDVVQ V+SV+RLEGT L Sbjct 421 LADLDVVQSVTSVLRLEGTSL 441 >gi|342858045|ref|ZP_08714701.1| homoserine dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342135378|gb|EGT88544.1| homoserine dehydrogenase [Mycobacterium colombiense CECT 3035] Length=440 Score = 760 bits (1962), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/441 (91%), Positives = 419/441 (96%), Gaps = 1/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +P DEKPVGVAVLGLGNVGSEVVRIIE+SA+DLAARVGAP+VLRG+GVRRV DRGVP+E Sbjct 1 MPRDEKPVGVAVLGLGNVGSEVVRIIEDSADDLAARVGAPVVLRGVGVRRVAADRGVPVE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIE L AR+DVDIVVE+MGPVEPSRKAIL ALE GKSVVTANKALLATSTGELAQA Sbjct 61 LLTDDIEALAARDDVDIVVELMGPVEPSRKAILCALEHGKSVVTANKALLATSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY + Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDT 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALA+A ALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADF S Sbjct 181 ALAEAGALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFES 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A ALGCTIKLLSICERIT D G +RVSARVYPALVPLSHPLA VNGAFNAVVVEA+A+GR Sbjct 241 ARALGCTIKLLSICERITAD-GQERVSARVYPALVPLSHPLATVNGAFNAVVVEAKASGR 299 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAV GD+VMAARNRVLGSRGP+ESKYAQLP+APMGFI TRYYVSMN Sbjct 300 LMFYGQGAGGAPTASAVAGDMVMAARNRVLGSRGPKESKYAQLPIAPMGFISTRYYVSMN 359 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS+VAAEFAKREVSIAEVRQEGV DEGGRRVGARIVVVTH ATDAALSETVDA Sbjct 360 VADKPGVLSSVAAEFAKREVSIAEVRQEGVADEGGRRVGARIVVVTHSATDAALSETVDA 419 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 L DLDVVQ V+SV+RLEGT L Sbjct 420 LADLDVVQSVTSVLRLEGTTL 440 >gi|41408566|ref|NP_961402.1| homoserine dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396924|gb|AAS04785.1| ThrA [Mycobacterium avium subsp. paratuberculosis K-10] Length=441 Score = 759 bits (1959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/441 (91%), Positives = 417/441 (95%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +P DEKPVGVAVLGLGNVGSEVVRIIE+SA DLAAR+GAPLVLRG+GVRRV DRGVP+E Sbjct 1 MPRDEKPVGVAVLGLGNVGSEVVRIIEDSAGDLAARIGAPLVLRGVGVRRVADDRGVPVE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIE L AR+DVDIVVE+MGPVEPSRKAIL ALE GKSVVTANKALL+TSTGELAQA Sbjct 61 LLTDDIEGLAARDDVDIVVELMGPVEPSRKAILCALEHGKSVVTANKALLSTSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDL+FEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY + Sbjct 121 AESAHVDLHFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDT 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALA+AS LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITK+TPADF S Sbjct 181 ALAEASDLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKITPADFAS 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A ALGCTIKLLSICERIT D+G +RVSARVYPALVPLSHPLA VNGAFNAVVVEA A+GR Sbjct 241 ARALGCTIKLLSICERITGDDGQERVSARVYPALVPLSHPLATVNGAFNAVVVEARASGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAV GDLVMAARNRVLGSRGPRESKYAQLPVAPMGFI TRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVAGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFISTRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS+VAAEFAKREVSIAEVRQEGV DEGGRRVGARIVVVTH ATDAALSETV A Sbjct 361 VADKPGVLSSVAAEFAKREVSIAEVRQEGVADEGGRRVGARIVVVTHTATDAALSETVHA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 L DLDVVQ V+SV+RLEGT L Sbjct 421 LADLDVVQSVTSVLRLEGTSL 441 >gi|254821293|ref|ZP_05226294.1| homoserine dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=441 Score = 754 bits (1947), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/441 (91%), Positives = 415/441 (95%), Gaps = 0/441 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +P +EKPVGVAVLGLGNVGSEVVRIIE SA+DLAARVGAPLVLRG+GVRRV DRGVP E Sbjct 1 MPREEKPVGVAVLGLGNVGSEVVRIIEESADDLAARVGAPLVLRGVGVRRVADDRGVPAE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIE L AR+DVDIVVE+MGPVEPSRKAIL ALE GKSVVTANKALL+ STGELAQA Sbjct 61 LLTDDIEGLAARDDVDIVVELMGPVEPSRKAILCALEHGKSVVTANKALLSISTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY + Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDT 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALA+ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADF S Sbjct 181 ALAEASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFES 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A ALGCTIKLLSICERIT +G +RVSARVYPALVPLSHPLA VNGAFNAVVVEA+A+GR Sbjct 241 ARALGCTIKLLSICERITDGDGQERVSARVYPALVPLSHPLATVNGAFNAVVVEAKASGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAV GDLVMAARNRVLGSRGPRESKYAQLPVAPMG I TRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVAGDLVMAARNRVLGSRGPRESKYAQLPVAPMGLISTRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS+VAAEFAKREVSIAEVRQEGV DEGGRRVGARIVVVTH ATDAALSETVDA Sbjct 361 VADKPGVLSSVAAEFAKREVSIAEVRQEGVADEGGRRVGARIVVVTHRATDAALSETVDA 420 Query 421 LDDLDVVQGVSSVIRLEGTGL 441 L DLD VQ V+SV+RLEGT L Sbjct 421 LADLDAVQSVTSVLRLEGTTL 441 >gi|296170235|ref|ZP_06851828.1| homoserine dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895111|gb|EFG74829.1| homoserine dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=441 Score = 745 bits (1923), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/440 (92%), Positives = 423/440 (97%), Gaps = 0/440 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +P DEKPVGVAVLGLGNVGSEVVRIIE+SA+DLAARVGAPLVLRG+GVRRV DRGVP+E Sbjct 1 MPRDEKPVGVAVLGLGNVGSEVVRIIEDSADDLAARVGAPLVLRGVGVRRVAADRGVPVE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTD+IEELV+REDVDIV+E+MGPVEP+RKAIL ALE GKSVVTANKALLATSTGELAQA Sbjct 61 LLTDNIEELVSREDVDIVLELMGPVEPARKAILRALEHGKSVVTANKALLATSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AE+AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYA+ Sbjct 121 AENAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAT 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALA+ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITK+TPADF S Sbjct 181 ALAEASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKITPADFAS 240 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A ALGCTIKLLSICERIT D+G +RVSARVYPALVPLSHPLA VNGAFNAVVVEA AAGR Sbjct 241 ARALGCTIKLLSICERITGDDGQERVSARVYPALVPLSHPLATVNGAFNAVVVEARAAGR 300 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGP+ESKYAQLP+APMGFI TRYYVSMN Sbjct 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPKESKYAQLPIAPMGFISTRYYVSMN 360 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 VADKPGVLS VAAEFAKREVSIAEVRQEGVVDEGGRRVGAR+VVVTH ATDAALSETVDA Sbjct 361 VADKPGVLSTVAAEFAKREVSIAEVRQEGVVDEGGRRVGARVVVVTHSATDAALSETVDA 420 Query 421 LDDLDVVQGVSSVIRLEGTG 440 L DLDVVQGV+SV+RLE G Sbjct 421 LADLDVVQGVTSVLRLEEAG 440 >gi|15827560|ref|NP_301823.1| homoserine dehydrogenase [Mycobacterium leprae TN] gi|221230037|ref|YP_002503453.1| homoserine dehydrogenase [Mycobacterium leprae Br4923] gi|1169334|sp|P46806.1|DHOM_MYCLE RecName: Full=Homoserine dehydrogenase; Short=HDH gi|699340|gb|AAA63101.1| metL [Mycobacterium leprae] gi|13093110|emb|CAC31510.1| homoserine dehydrogenase [Mycobacterium leprae] gi|219933144|emb|CAR71224.1| homoserine dehydrogenase [Mycobacterium leprae Br4923] Length=441 Score = 740 bits (1911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/438 (90%), Positives = 411/438 (94%), Gaps = 0/438 (0%) Query 4 DEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLT 63 DE+ VGVAVLGLGNVGSEVVRIIE SA+DLAAR+GAPL+LRGIGVRRV DRGVP++LLT Sbjct 4 DERTVGVAVLGLGNVGSEVVRIIEGSADDLAARIGAPLMLRGIGVRRVAVDRGVPVDLLT 63 Query 64 DDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAES 123 D+IEELV+R DVDIVVEVMGPVE SRKAIL ALE GKSVVTANKALLA STGELAQAAES Sbjct 64 DNIEELVSRADVDIVVEVMGPVELSRKAILSALEHGKSVVTANKALLAASTGELAQAAES 123 Query 124 AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALA 183 AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY SALA Sbjct 124 AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDSALA 183 Query 184 DASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHA 243 A ALGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITK+TPADF SA A Sbjct 184 GARALGYAEADPTADVEGHDAAAKAAILASIAFHTRVTADDVYREGITKITPADFVSARA 243 Query 244 LGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMF 303 LGCTIKLL ICERIT +G QRVSARVYPALVP+SHPLA V+GAFNAVVVEAEAAGRLMF Sbjct 244 LGCTIKLLFICERITAADGQQRVSARVYPALVPMSHPLATVSGAFNAVVVEAEAAGRLMF 303 Query 304 YGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVAD 363 YGQGAGGAPTASAVTGDLVMAARNRVLGSRGP+ESKYAQLP+ +GFI TRYYVSMNVAD Sbjct 304 YGQGAGGAPTASAVTGDLVMAARNRVLGSRGPKESKYAQLPMETIGFISTRYYVSMNVAD 363 Query 364 KPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDD 423 KPGVLS VAAEFAKREVSIAEVRQEGVVD+GGRRVGARIVVVTH ATDAALSETVDAL D Sbjct 364 KPGVLSGVAAEFAKREVSIAEVRQEGVVDDGGRRVGARIVVVTHGATDAALSETVDALAD 423 Query 424 LDVVQGVSSVIRLEGTGL 441 LDVVQGV+SV+RLEG L Sbjct 424 LDVVQGVTSVLRLEGISL 441 >gi|126436458|ref|YP_001072149.1| homoserine dehydrogenase [Mycobacterium sp. JLS] gi|126236258|gb|ABN99658.1| homoserine dehydrogenase [Mycobacterium sp. JLS] Length=445 Score = 723 bits (1866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/435 (87%), Positives = 407/435 (94%), Gaps = 0/435 (0%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 + PVGVAVLGLGNVGSEVVRIIE SA DLAARVGAPLVLRG+GVRRV DRGVP+++LTD Sbjct 9 DTPVGVAVLGLGNVGSEVVRIIEQSATDLAARVGAPLVLRGVGVRRVAGDRGVPVDMLTD 68 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 +IEELV+REDVDIVVEVMGPVEP+RKAIL ALE+GKSVVTANKAL+A STGELAQAAE+A Sbjct 69 NIEELVSREDVDIVVEVMGPVEPARKAILSALEQGKSVVTANKALMAQSTGELAQAAEAA 128 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAM+ TGADY SALAD Sbjct 129 RVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMNDTGADYDSALAD 188 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 ASALGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITKVT DF SA +L Sbjct 189 ASALGYAEADPTADVEGFDAAAKAAILASIAFHTRVTADDVYREGITKVTAEDFESARSL 248 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER+TTD+G QRVSARVYPALVPL HPLA+VNGAFNAVVVEAEAAGRLMFY Sbjct 249 GCTIKLLAICERLTTDDGQQRVSARVYPALVPLDHPLASVNGAFNAVVVEAEAAGRLMFY 308 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARNRV G RGPRESKYA+LPV+P+GFI TRYYV+MNVAD+ Sbjct 309 GQGAGGAPTASAVMGDLVMAARNRVQGGRGPRESKYAKLPVSPIGFIPTRYYVNMNVADR 368 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVLS VAAEFA+ EVSIAEVRQEGVVDEGG+ GARIVVVTH ATDAALSETV AL +L Sbjct 369 PGVLSTVAAEFARHEVSIAEVRQEGVVDEGGQPCGARIVVVTHRATDAALSETVSALAEL 428 Query 425 DVVQGVSSVIRLEGT 439 DVVQ V+SV+R+EGT Sbjct 429 DVVQSVNSVLRMEGT 443 >gi|118473179|ref|YP_889209.1| homoserine dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118174466|gb|ABK75362.1| homoserine dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=439 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/435 (87%), Positives = 406/435 (94%), Gaps = 0/435 (0%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 +KP+GVAVLGLGNVGSEVVRII +SA+DLAAR+GAPL LRG+GVRRV DRGVP ELLTD Sbjct 3 KKPIGVAVLGLGNVGSEVVRIIADSADDLAARIGAPLELRGVGVRRVADDRGVPTELLTD 62 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 DI+ LV+R+DVDIVVEVMGPVEP+RKAIL ALE+GKSVVTANKAL+A STGELAQAAE A Sbjct 63 DIDALVSRDDVDIVVEVMGPVEPARKAILSALEQGKSVVTANKALMAMSTGELAQAAEKA 122 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 HVDLYFEAAVAGAIPVIRPLTQSLAGDTV RVAGIVNGTTNYILS MDSTGADY SALAD Sbjct 123 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVRRVAGIVNGTTNYILSEMDSTGADYTSALAD 182 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGIT V+ DF SA AL Sbjct 183 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITTVSAEDFASARAL 242 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER+T+DEG RVSARVYPALVPL+HPLAAVNGAFNAVVVEAEAAGRLMFY Sbjct 243 GCTIKLLAICERLTSDEGKDRVSARVYPALVPLTHPLAAVNGAFNAVVVEAEAAGRLMFY 302 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GD+VMAARNRV G RGPRESKYA+LP+AP+GFI TRYYV+MNVAD+ Sbjct 303 GQGAGGAPTASAVMGDVVMAARNRVQGGRGPRESKYAKLPIAPIGFIPTRYYVNMNVADR 362 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVLSAVAAEFAKREVSI+EVRQEG+VDE G+ GARIVVVTH ATDAALSETV+AL DL Sbjct 363 PGVLSAVAAEFAKREVSISEVRQEGMVDEVGKPCGARIVVVTHSATDAALSETVEALADL 422 Query 425 DVVQGVSSVIRLEGT 439 DVVQ ++SV+RLEGT Sbjct 423 DVVQNINSVLRLEGT 437 >gi|108800860|ref|YP_641057.1| homoserine dehydrogenase [Mycobacterium sp. MCS] gi|119870000|ref|YP_939952.1| homoserine dehydrogenase [Mycobacterium sp. KMS] gi|108771279|gb|ABG10001.1| homoserine dehydrogenase [Mycobacterium sp. MCS] gi|119696089|gb|ABL93162.1| homoserine dehydrogenase [Mycobacterium sp. KMS] Length=445 Score = 721 bits (1860), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/435 (87%), Positives = 406/435 (94%), Gaps = 0/435 (0%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 + PVGVAVLGLGNVGSEVV IIE SA DLAARVGAPLVLRG+GVRRV DRGVP+++LTD Sbjct 9 DTPVGVAVLGLGNVGSEVVHIIEQSATDLAARVGAPLVLRGVGVRRVAGDRGVPVDMLTD 68 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 +IEELV+REDVDIVVEVMGPVEP+RKAIL ALE+GKSVVTANKAL+A STGELAQAAE+A Sbjct 69 NIEELVSREDVDIVVEVMGPVEPARKAILSALEQGKSVVTANKALMAQSTGELAQAAEAA 128 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAM+ TGADY SALAD Sbjct 129 RVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMNDTGADYDSALAD 188 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 ASALGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITKVT DF SA +L Sbjct 189 ASALGYAEADPTADVEGFDAAAKAAILASIAFHTRVTADDVYREGITKVTAEDFESARSL 248 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER+TTD+G QRVSARVYPALVPL HPLA+VNGAFNAVVVEAEAAGRLMFY Sbjct 249 GCTIKLLAICERLTTDDGQQRVSARVYPALVPLDHPLASVNGAFNAVVVEAEAAGRLMFY 308 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARNRV G RGPRESKYA+LPV+P+GFI TRYYV+MNVAD+ Sbjct 309 GQGAGGAPTASAVMGDLVMAARNRVQGGRGPRESKYAKLPVSPIGFIPTRYYVNMNVADR 368 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVLS VAAEFA+ EVSIAEVRQEGVVDEGG+ GARIVVVTH ATDAALSETV AL +L Sbjct 369 PGVLSTVAAEFARHEVSIAEVRQEGVVDEGGQPCGARIVVVTHRATDAALSETVSALAEL 428 Query 425 DVVQGVSSVIRLEGT 439 DVVQ V+SV+R+EGT Sbjct 429 DVVQSVNSVLRMEGT 443 >gi|120405302|ref|YP_955131.1| homoserine dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119958120|gb|ABM15125.1| homoserine dehydrogenase [Mycobacterium vanbaalenii PYR-1] Length=438 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/432 (86%), Positives = 403/432 (94%), Gaps = 0/432 (0%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIE 67 +GVAVLGLGNVGSEVVRIIE SA DL AR+GAPLV+RGIGVRRV DRGVP+ELLTDDIE Sbjct 5 IGVAVLGLGNVGSEVVRIIEESAADLTARIGAPLVIRGIGVRRVDADRGVPVELLTDDIE 64 Query 68 ELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVD 127 LV+R+DVDIVVE+MGPVEP+RKAIL ALE+GKSVVTANKAL+A S G+LA+AAE AHVD Sbjct 65 ALVSRDDVDIVVELMGPVEPARKAILAALEQGKSVVTANKALMAVSAGKLAEAAEKAHVD 124 Query 128 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASA 187 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYASALADASA Sbjct 125 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYASALADASA 184 Query 188 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCT 247 LGYAEADPTADVEG+DAAAKAAILASIAFHTRVTADDVYREGITKV+ ADF SA ALGCT Sbjct 185 LGYAEADPTADVEGWDAAAKAAILASIAFHTRVTADDVYREGITKVSAADFASARALGCT 244 Query 248 IKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQG 307 IKLL+ICER+TT +G Q+VSARVYPALVPL HPLA+VNGAFNAVVVEAEAAGRLMFYGQG Sbjct 245 IKLLAICERLTTGKGKQQVSARVYPALVPLEHPLASVNGAFNAVVVEAEAAGRLMFYGQG 304 Query 308 AGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGV 367 AGGAPTASAV GDLVMAARNRV G RGPRESKYA+LPVAP+G I TRYYV+MNVAD+PGV Sbjct 305 AGGAPTASAVLGDLVMAARNRVQGGRGPRESKYAKLPVAPIGVIPTRYYVNMNVADRPGV 364 Query 368 LSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVV 427 LSAV+AEF+KREVSIAEVRQEG+VD+ G+R GARIVVVTH A DAALSETV AL DLDVV Sbjct 365 LSAVSAEFSKREVSIAEVRQEGMVDDEGQRCGARIVVVTHQAKDAALSETVAALADLDVV 424 Query 428 QGVSSVIRLEGT 439 Q ++SV+R+EGT Sbjct 425 QSINSVLRMEGT 436 >gi|145222886|ref|YP_001133564.1| homoserine dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|145215372|gb|ABP44776.1| homoserine dehydrogenase [Mycobacterium gilvum PYR-GCK] Length=438 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/432 (86%), Positives = 400/432 (93%), Gaps = 0/432 (0%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIE 67 +GVAVLGLGNVGS+VVRIIE SA DL AR+GAPLV+RGIGVR V+ DRGVP ELLTDDI+ Sbjct 5 IGVAVLGLGNVGSQVVRIIEESATDLTARIGAPLVVRGIGVRDVSRDRGVPAELLTDDID 64 Query 68 ELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVD 127 LV+R+DVDIVVE+MGPVEP+RKAIL ALE+GKSVVTANKAL+A S G+LA+AAE+A VD Sbjct 65 ALVSRDDVDIVVELMGPVEPARKAILAALEQGKSVVTANKALMAVSAGKLAEAAENARVD 124 Query 128 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASA 187 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYASALADASA Sbjct 125 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYASALADASA 184 Query 188 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCT 247 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVT ADF SA ALGCT Sbjct 185 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTAADFVSARALGCT 244 Query 248 IKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQG 307 IKLL+ICER+T+ +G Q+VSARVYPALVPL HPLA+VNGAFNAVVVEAEAAGRLMFYGQG Sbjct 245 IKLLAICERLTSPKGKQKVSARVYPALVPLEHPLASVNGAFNAVVVEAEAAGRLMFYGQG 304 Query 308 AGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGV 367 AGGAPTASAV GDLVMAARNRV G RGPRESKYA+LPVAP+G I TRYYV+MNV D+PGV Sbjct 305 AGGAPTASAVLGDLVMAARNRVQGGRGPRESKYAKLPVAPIGVIPTRYYVNMNVKDRPGV 364 Query 368 LSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVV 427 LSAVAAEF+ REVSIAEVRQEG+VDE G+R GARIVVVTH ATD ALSETV AL DLDVV Sbjct 365 LSAVAAEFSAREVSIAEVRQEGMVDEDGQRSGARIVVVTHEATDEALSETVAALADLDVV 424 Query 428 QGVSSVIRLEGT 439 Q ++SV+RLEGT Sbjct 425 QSINSVLRLEGT 436 >gi|315443351|ref|YP_004076230.1| homoserine dehydrogenase [Mycobacterium sp. Spyr1] gi|315261654|gb|ADT98395.1| homoserine dehydrogenase [Mycobacterium sp. Spyr1] Length=438 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/432 (86%), Positives = 400/432 (93%), Gaps = 0/432 (0%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIE 67 +GVAVLGLGNVGS+VVRIIE SA DL AR+GAPLV+RGIGVR V+ DRGVP ELLTDDI+ Sbjct 5 IGVAVLGLGNVGSQVVRIIEESATDLTARIGAPLVVRGIGVRDVSRDRGVPAELLTDDID 64 Query 68 ELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVD 127 LV+R+DVDIVVE+MGPVEP+RKAIL ALE+GKSVVTANKAL+A S G+LA+AAE+A VD Sbjct 65 ALVSRDDVDIVVELMGPVEPARKAILAALEQGKSVVTANKALMAVSAGKLAEAAENARVD 124 Query 128 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASA 187 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYASALADASA Sbjct 125 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYASALADASA 184 Query 188 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCT 247 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVT ADF SA ALGCT Sbjct 185 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTAADFVSARALGCT 244 Query 248 IKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQG 307 IKLL+ICER+T+ +G Q+VSARVYPALVPL HPLA+VNGAFNAVVVEAEAAGRLMFYGQG Sbjct 245 IKLLAICERLTSPKGKQKVSARVYPALVPLEHPLASVNGAFNAVVVEAEAAGRLMFYGQG 304 Query 308 AGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGV 367 AGGAPTASAV GDLVMAARNRV G RGPRESKYA+LPVAP+G I TRYYV+MNV D+PGV Sbjct 305 AGGAPTASAVLGDLVMAARNRVQGGRGPRESKYAKLPVAPIGVIPTRYYVNMNVNDRPGV 364 Query 368 LSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVV 427 LSAVAAEF+ REVSIAEVRQEG+VDE G+R GARIVVVTH ATD ALSETV AL DLDVV Sbjct 365 LSAVAAEFSAREVSIAEVRQEGMVDEDGQRSGARIVVVTHEATDEALSETVAALADLDVV 424 Query 428 QGVSSVIRLEGT 439 Q ++SV+RLEGT Sbjct 425 QSINSVLRLEGT 436 >gi|333989933|ref|YP_004522547.1| homoserine dehydrogenase [Mycobacterium sp. JDM601] gi|333485901|gb|AEF35293.1| homoserine dehydrogenase ThrA [Mycobacterium sp. JDM601] Length=434 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/432 (83%), Positives = 394/432 (92%), Gaps = 0/432 (0%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIE 67 +GVAVLGLGNVGSEVVRI+E SA+DLAAR+GAPLVLRG+GVRRV DRGVP+ELLTDD++ Sbjct 1 MGVAVLGLGNVGSEVVRILEASADDLAARIGAPLVLRGVGVRRVADDRGVPVELLTDDVD 60 Query 68 ELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVD 127 LV+R DVDIVVE+MGPVEP+R AIL A++ GKSV+TANKALL+ STGELA+AAE+A VD Sbjct 61 SLVSRSDVDIVVELMGPVEPARNAILSAIKHGKSVITANKALLSRSTGELAEAAETARVD 120 Query 128 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASA 187 +YFEA+VAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILS MDSTGADYASALADASA Sbjct 121 MYFEASVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSEMDSTGADYASALADASA 180 Query 188 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCT 247 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGIT +TP D +A ALGCT Sbjct 181 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITNITPEDAAAARALGCT 240 Query 248 IKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQG 307 IKLL+ICERI++ G QRVSARVYPALVPL HPLA VNGAFNAVVVEAEAAGRLMFYGQG Sbjct 241 IKLLAICERISSRGGQQRVSARVYPALVPLEHPLATVNGAFNAVVVEAEAAGRLMFYGQG 300 Query 308 AGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGV 367 AGG+PTASAV GDLVMAARNRV G RGPRESKYAQL +AP+G ++TRYYVSM+VADKPGV Sbjct 301 AGGSPTASAVMGDLVMAARNRVQGGRGPRESKYAQLAIAPIGDVQTRYYVSMDVADKPGV 360 Query 368 LSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVV 427 L+ VAAEFA EVSIAEVRQEGV DE G+ +GARIVVVTH A ++ALSETV AL +LD V Sbjct 361 LATVAAEFAAHEVSIAEVRQEGVTDEEGQPIGARIVVVTHRAAESALSETVAALAELDAV 420 Query 428 QGVSSVIRLEGT 439 Q V+SV+RLEGT Sbjct 421 QQVASVLRLEGT 432 >gi|169628526|ref|YP_001702175.1| homoserine dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169240493|emb|CAM61521.1| Probable homoserine dehydrogenase [Mycobacterium abscessus] Length=434 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/432 (82%), Positives = 384/432 (89%), Gaps = 4/432 (0%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDIE 67 +GVA+LGLGNVGSEV RIIE+SA DLAAR+GAPL +RGIGVRRV RGVP++LLTDDIE Sbjct 5 IGVAILGLGNVGSEVARIIESSASDLAARIGAPLEIRGIGVRRVADGRGVPVDLLTDDIE 64 Query 68 ELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVD 127 LVAR+DVDIVVE+MGPVEP+R+ ILGAL GKSVVTANKALLA S GELA+AAE A VD Sbjct 65 ALVARDDVDIVVELMGPVEPARRGILGALNAGKSVVTANKALLAQSAGELAEAAEKARVD 124 Query 128 LYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASA 187 LYFEAAVAGAIPVIRPLTQSLAGD+V+RV+GIVNGTTNYILSAMD+TGA Y +ALA+A Sbjct 125 LYFEAAVAGAIPVIRPLTQSLAGDSVIRVSGIVNGTTNYILSAMDNTGAGYGTALAEAGE 184 Query 188 LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCT 247 LGYAEADPTADVEGYDAAAKAAILASIAFHT+V+ADDVYREGITK++ DF SA AL C+ Sbjct 185 LGYAEADPTADVEGYDAAAKAAILASIAFHTKVSADDVYREGITKISADDFDSARALQCS 244 Query 248 IKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQG 307 IKLLSICER+T EG QRVSARVYPALVPL+HPLA+VNGAFNAV VEAEAAG LMFYGQG Sbjct 245 IKLLSICERLTDSEGHQRVSARVYPALVPLTHPLASVNGAFNAVFVEAEAAGELMFYGQG 304 Query 308 AGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGV 367 AGGAPTASAV GDLVMAARNRV G RGPR S+YAQLPVAP+G I TRYYV M VADKPGV Sbjct 305 AGGAPTASAVLGDLVMAARNRVQGGRGPRASRYAQLPVAPIGLIPTRYYVRMRVADKPGV 364 Query 368 LSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVV 427 L+ VAAEFAKREVSIA VRQEG VDE GAR+VV+TH ATDAALSETV AL DLDVV Sbjct 365 LATVAAEFAKREVSIATVRQEGEVDE----TGARLVVLTHKATDAALSETVAALADLDVV 420 Query 428 QGVSSVIRLEGT 439 GV+SVIRLEGT Sbjct 421 LGVASVIRLEGT 432 >gi|4894690|gb|AAD32592.1|AF126720_3 homoserine dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=373 Score = 622 bits (1604), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 324/371 (88%), Positives = 347/371 (94%), Gaps = 0/371 (0%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 +KP+GVAVLGLGNVGSEVVRII +SA+DLAAR+GAPL LRG+GVRRV DRGVP ELLTD Sbjct 3 KKPIGVAVLGLGNVGSEVVRIIADSADDLAARIGAPLELRGVGVRRVADDRGVPTELLTD 62 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 DI+ LV+R+DVDIVVEVMGPVEP+RKAIL ALE+GKSVVTANKAL+A STGELAQAAE A Sbjct 63 DIDALVSRDDVDIVVEVMGPVEPARKAILSALEQGKSVVTANKALMAMSTGELAQAAEKA 122 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 HVDLYFEAAVAGAIPVIRPLTQSLAGDTV RVAGIVNGTTNYILS MDSTGADY SALAD Sbjct 123 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVRRVAGIVNGTTNYILSEMDSTGADYTSALAD 182 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGIT V+ DF SA AL Sbjct 183 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITTVSAEDFASARAL 242 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER+T+DEG RVSARVYPALVPL+HPLAAVNGAFNAVVVEAEAAGRLMFY Sbjct 243 GCTIKLLAICERLTSDEGKDRVSARVYPALVPLTHPLAAVNGAFNAVVVEAEAAGRLMFY 302 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTA AV GD+VMAARNRV G RGPRESKYA+LP+AP+GFI TRYYV+MNVAD+ Sbjct 303 GQGAGGAPTAFAVMGDVVMAARNRVQGGRGPRESKYAKLPIAPIGFIPTRYYVNMNVADR 362 Query 365 PGVLSAVAAEF 375 PGVLSAVAAEF Sbjct 363 PGVLSAVAAEF 373 >gi|226307409|ref|YP_002767369.1| homoserine dehydrogenase [Rhodococcus erythropolis PR4] gi|226186526|dbj|BAH34630.1| homoserine dehydrogenase [Rhodococcus erythropolis PR4] Length=437 Score = 612 bits (1577), Expect = 5e-173, Method: Compositional matrix adjust. Identities = 333/435 (77%), Positives = 366/435 (85%), Gaps = 6/435 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 + +GVAVLGLGNVGSEVVRII AE+L ARVGAPL LRG+ VRR+ +DRG+P EL T Sbjct 7 HRAIGVAVLGLGNVGSEVVRIIREQAEELEARVGAPLELRGVAVRRIGSDRGIPEELQTT 66 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D E LV R+DVDIVVEV+G +E RK IL +L GKSVVTANKALLA TGELA+AAE+ Sbjct 67 DAESLVGRDDVDIVVEVIGGIELPRKLILSSLNSGKSVVTANKALLADHTGELAEAAEAN 126 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLYFEAAVAGAIPVIRPLTQSLAGD V +VAGIVNGTTN+ILSAMD TGADY LA+ Sbjct 127 SVDLYFEAAVAGAIPVIRPLTQSLAGDRVNKVAGIVNGTTNFILSAMDETGADYEETLAE 186 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTA DVYREGI+ +T AD SA AL Sbjct 187 AGRLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTAADVYREGISTITSADLASAKAL 246 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CTIKLLSICERI T +G +R+SARVYPALVPLSHPLA+VNGAFNAVVVEAE AGRLMFY Sbjct 247 DCTIKLLSICERIVTPKGKERISARVYPALVPLSHPLASVNGAFNAVVVEAENAGRLMFY 306 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARN+V G RGPRESKYA+L VAPMG I TRYYV+M VADK Sbjct 307 GQGAGGAPTASAVMGDLVMAARNKVHGGRGPRESKYAKLKVAPMGDILTRYYVNMEVADK 366 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 GVLSAVAAEFAK VSI+ VRQEG GAR+VVVTH+ATDAALSETV AL++L Sbjct 367 EGVLSAVAAEFAKHGVSISVVRQEGA------GAGARLVVVTHVATDAALSETVAALNEL 420 Query 425 DVVQGVSSVIRLEGT 439 + V V+SV+RLEGT Sbjct 421 EFVTAVTSVLRLEGT 435 >gi|226360612|ref|YP_002778390.1| homoserine dehydrogenase [Rhodococcus opacus B4] gi|226239097|dbj|BAH49445.1| homoserine dehydrogenase [Rhodococcus opacus B4] Length=437 Score = 607 bits (1565), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 330/435 (76%), Positives = 367/435 (85%), Gaps = 6/435 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 + +GVAVLGLGNVGSEVVRI+ +EDL ARVGAPL LRG+ VRR DRG+P EL T Sbjct 7 HRAIGVAVLGLGNVGSEVVRILREHSEDLEARVGAPLELRGVAVRRPGKDRGIPEELQTT 66 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D E LVAR+DVD+VVEV+G ++ RK IL AL GKSVVTANKALLA TGELA+AAE Sbjct 67 DAESLVARDDVDLVVEVIGGMDLPRKLILSALNSGKSVVTANKALLADHTGELAEAAELH 126 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 +VDLYFEAAVAGAIPVIRPL QSLAGD V +VAGIVNGTTN+ILSAMD TGADYA+ LA+ Sbjct 127 NVDLYFEAAVAGAIPVIRPLIQSLAGDRVNKVAGIVNGTTNFILSAMDETGADYAATLAE 186 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTA DVYREGI+K+T AD SA AL Sbjct 187 AGRLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTAADVYREGISKITAADLTSARAL 246 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CTIKLLSICERITT EG +R+SARVYPALVPL HPLA+VNGAFNAVVVEAE AGRLMFY Sbjct 247 DCTIKLLSICERITTPEGKERISARVYPALVPLEHPLASVNGAFNAVVVEAENAGRLMFY 306 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARN+V G RGPRESKYA+L +AP+G I TRYYV+M VADK Sbjct 307 GQGAGGAPTASAVMGDLVMAARNKVNGGRGPRESKYAKLKIAPIGDIPTRYYVNMQVADK 366 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 GVLSAVAAEF++ VSI+ VRQEG D GAR+VVVTH+ATD+ALSETV+AL L Sbjct 367 AGVLSAVAAEFSQHGVSISTVRQEGAGD------GARLVVVTHVATDSALSETVEALSKL 420 Query 425 DVVQGVSSVIRLEGT 439 + V V+SV+RLEGT Sbjct 421 EFVTAVTSVLRLEGT 435 >gi|111018489|ref|YP_701461.1| homoserine dehydrogenase [Rhodococcus jostii RHA1] gi|110818019|gb|ABG93303.1| homoserine dehydrogenase [Rhodococcus jostii RHA1] Length=437 Score = 605 bits (1559), Expect = 6e-171, Method: Compositional matrix adjust. Identities = 329/435 (76%), Positives = 365/435 (84%), Gaps = 6/435 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 + +GVAVLGLGNVGSEVVRI+ +EDL ARVGAPL LRG+ VRR DRG+P EL T Sbjct 7 HRAIGVAVLGLGNVGSEVVRILREHSEDLEARVGAPLELRGVAVRRPGKDRGIPEELQTT 66 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D E LVAR+DVDIVVEV+G ++ RK IL AL GKSVVTANKALLA TGELA+AAE Sbjct 67 DAESLVARDDVDIVVEVIGGMDLPRKLILSALNSGKSVVTANKALLADHTGELAEAAELH 126 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 +VDLYFEAAVAGAIPVIRPL QSLAGD V +VAGIVNGTTN+ILSAMD TGADYA+ LA+ Sbjct 127 NVDLYFEAAVAGAIPVIRPLIQSLAGDRVNKVAGIVNGTTNFILSAMDETGADYAATLAE 186 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A LGYAEADPTADVEGYDAAAKAAILASIAFHTRVTA DVYREGI+K+T AD SA AL Sbjct 187 AGRLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTAADVYREGISKITAADLTSARAL 246 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CTIKLLSICERI T EG +R+SARVYPALVPL HPLA+VNGAFNAVVVEAE AGRLMFY Sbjct 247 DCTIKLLSICERIATPEGKERISARVYPALVPLEHPLASVNGAFNAVVVEAENAGRLMFY 306 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARN+V G RGPRESKYA+L +AP+G I TRYYV+M V DK Sbjct 307 GQGAGGAPTASAVMGDLVMAARNKVNGGRGPRESKYAKLKIAPIGDIPTRYYVNMQVTDK 366 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 GVLSAVAAEF++ VSI+ VRQEG D GAR+VVVTH+ATD+ALSETV+AL L Sbjct 367 AGVLSAVAAEFSQHGVSISTVRQEGAGD------GARLVVVTHVATDSALSETVEALSKL 420 Query 425 DVVQGVSSVIRLEGT 439 + V V+SV+RLEGT Sbjct 421 EFVTAVTSVLRLEGT 435 >gi|312139161|ref|YP_004006497.1| homoserine dehydrogenase thra [Rhodococcus equi 103S] gi|325673534|ref|ZP_08153225.1| homoserine dehydrogenase [Rhodococcus equi ATCC 33707] gi|311888500|emb|CBH47812.1| homoserine dehydrogenase ThrA [Rhodococcus equi 103S] gi|325555555|gb|EGD25226.1| homoserine dehydrogenase [Rhodococcus equi ATCC 33707] Length=437 Score = 591 bits (1523), Expect = 9e-167, Method: Compositional matrix adjust. Identities = 322/435 (75%), Positives = 356/435 (82%), Gaps = 6/435 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 ++ +GVAVLGLG VGSEV RII + DL ARVGA L LRG+ VRR+ DRG+P ELLT Sbjct 7 QRAIGVAVLGLGTVGSEVARIIREHSTDLEARVGARLELRGVAVRRIDGDRGLPEELLTT 66 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D E LV R+DVD+VVEV+G +E RK +L AL GKSVVTANKALLA TGELA+AAE Sbjct 67 DAESLVTRDDVDVVVEVIGGIELPRKLVLAALNAGKSVVTANKALLAEYTGELAEAAERQ 126 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLYFEAAVAGAIPVIRPLTQSLAGD V RV GIVNGTTN+ILSAMD TGADYA LA+ Sbjct 127 SVDLYFEAAVAGAIPVIRPLTQSLAGDRVDRVLGIVNGTTNFILSAMDETGADYADTLAE 186 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A LGYAEADPTADVEG+DAA+KAAILASIAFHTRVTA DVYREGI+K+T D +A +L Sbjct 187 AGRLGYAEADPTADVEGFDAASKAAILASIAFHTRVTAGDVYREGISKITSDDLDAAKSL 246 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CTIKLLSICERI G +RVSARVYPALVP HPLA VNGA+NAVVVE+ AGRLMFY Sbjct 247 DCTIKLLSICERIVDANGGERVSARVYPALVPREHPLAGVNGAYNAVVVESANAGRLMFY 306 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARN+V G RGPRESKYAQLP+APMG I TRYYV+M VAD+ Sbjct 307 GQGAGGAPTASAVMGDLVMAARNKVHGGRGPRESKYAQLPIAPMGDIPTRYYVNMQVADR 366 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 GVLSAVAAEFA R VSI+ VRQEG D GAR+VVVTHLA DAALSETV AL +L Sbjct 367 AGVLSAVAAEFANRGVSISTVRQEGAGD------GARLVVVTHLANDAALSETVAALAEL 420 Query 425 DVVQGVSSVIRLEGT 439 + V V+SV+RLEGT Sbjct 421 ESVTAVTSVLRLEGT 435 >gi|262201841|ref|YP_003273049.1| homoserine dehydrogenase [Gordonia bronchialis DSM 43247] gi|262085188|gb|ACY21156.1| Homoserine dehydrogenase [Gordonia bronchialis DSM 43247] Length=448 Score = 590 bits (1521), Expect = 2e-166, Method: Compositional matrix adjust. Identities = 311/434 (72%), Positives = 353/434 (82%), Gaps = 6/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDD 65 + +GVAVLG+GNVG+EVVRII ++A DL ARVGAP+ LRG+ VR + R + ELLTDD Sbjct 19 RSIGVAVLGMGNVGAEVVRIISDNAADLQARVGAPVQLRGVAVRDLARPRAIDPELLTDD 78 Query 66 IEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAH 125 LVAR+DVDIVVE+MG ++P+R I ALE GKSVVTANKALLA TGELA AA A Sbjct 79 PGALVARDDVDIVVELMGGIDPARGLIRAALENGKSVVTANKALLAEYTGELATAAARAK 138 Query 126 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADA 185 VDLYFEAAVAGAIPV+RPL QSLAGDTV RVAGIVNGTTN+ILSAMD TGADY + LA+A Sbjct 139 VDLYFEAAVAGAIPVVRPLMQSLAGDTVERVAGIVNGTTNFILSAMDETGADYEATLAEA 198 Query 186 SALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALG 245 LGYAEADPTADVEGYDAA+KAAILASIAFHTRVTA DVYREGI+ VT D +A Sbjct 199 GRLGYAEADPTADVEGYDAASKAAILASIAFHTRVTAADVYREGISAVTADDLVAAKKFD 258 Query 246 CTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYG 305 CT+KLLSICER+ +GS+RVSARVYPAL+PL+HPLA+VNGAFNAVVVEAE AGRLMFYG Sbjct 259 CTVKLLSICERVHDADGSERVSARVYPALIPLTHPLASVNGAFNAVVVEAENAGRLMFYG 318 Query 306 QGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKP 365 QGAGGAPTASAV GD+VMAARNRV G RGP ES YA LP+AP+ + TRYY+SM VAD+P Sbjct 319 QGAGGAPTASAVLGDMVMAARNRVHGGRGPLESTYASLPIAPVDDVPTRYYISMRVADRP 378 Query 366 GVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLD 425 GVL+ VA EF KR VSIA VRQEG D+ AR++VVTH A D A SE V AL+D+D Sbjct 379 GVLAQVAGEFTKRSVSIAAVRQEGAGDD------ARLIVVTHRAPDRAQSECVAALEDMD 432 Query 426 VVQGVSSVIRLEGT 439 V VSSV+RLEGT Sbjct 433 AVIKVSSVLRLEGT 446 >gi|326382076|ref|ZP_08203769.1| homoserine dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326199502|gb|EGD56683.1| homoserine dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=435 Score = 583 bits (1502), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 307/435 (71%), Positives = 350/435 (81%), Gaps = 8/435 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+GVAVLG+GNVG+EVVRI+ + A+DL ARVGAPLVLRG+ VR + R G+ LLT+ Sbjct 6 RPIGVAVLGMGNVGTEVVRILTDKADDLQARVGAPLVLRGVAVRDASRARDGIDPSLLTE 65 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D +ELV R DVD+VVE++G +EP+R IL AL GKSVVTANKAL+A +GELA+ AE Sbjct 66 DPQELVGRADVDMVVELIGGIEPARTLILAALGSGKSVVTANKALIAAHSGELAKTAEDN 125 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLYFEAAVAGAIPVIRPLTQSLAGD+V RVAGIVNGTTNYILS MD TGA YA LA+ Sbjct 126 RVDLYFEAAVAGAIPVIRPLTQSLAGDSVNRVAGIVNGTTNYILSEMDETGAGYAKVLAE 185 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A LGYAEADPTADVEGYDAA+KAAILASIAFH+RVTA DVYREGIT +T D +A Sbjct 186 AGRLGYAEADPTADVEGYDAASKAAILASIAFHSRVTASDVYREGITNITSKDLEAAKKF 245 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CT+KLL+ICERI T +G +++SARVYPALVPL HPLA VNGAFNAV VEAE AGRLMFY Sbjct 246 DCTVKLLAICERIQTPDG-EKISARVYPALVPLDHPLATVNGAFNAVAVEAENAGRLMFY 304 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLVMAARNRV RGP ES YA LPVA + + TRYYVSM VAD+ Sbjct 305 GQGAGGAPTASAVLGDLVMAARNRVYHGRGPLESTYASLPVASIDEVPTRYYVSMKVADR 364 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL VA EF+KR+VSIA VRQEG D AR++VVTH A+D A SETV AL+ + Sbjct 365 PGVLQQVAGEFSKRDVSIAAVRQEGAGDN------ARLIVVTHRASDRAQSETVAALEKM 418 Query 425 DVVQGVSSVIRLEGT 439 D V VSSV+RLEGT Sbjct 419 DSVLKVSSVLRLEGT 433 >gi|343928052|ref|ZP_08767517.1| homoserine dehydrogenase [Gordonia alkanivorans NBRC 16433] gi|343762060|dbj|GAA14443.1| homoserine dehydrogenase [Gordonia alkanivorans NBRC 16433] Length=447 Score = 573 bits (1478), Expect = 2e-161, Method: Compositional matrix adjust. Identities = 312/434 (72%), Positives = 355/434 (82%), Gaps = 6/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDD 65 +P+GVAVLG+GNVG+EVVRII ++A+DL ARVGAP+ +RG+ VR + R + ELLTDD Sbjct 18 RPIGVAVLGMGNVGAEVVRIITDNADDLRARVGAPVEIRGVAVRDLNRPRKIGQELLTDD 77 Query 66 IEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAH 125 L+AR+DVDIVVE+MG ++P+R I ALE GKSVVTANKALLA TGELA AA A Sbjct 78 PASLIARDDVDIVVELMGGIDPARALIRTALESGKSVVTANKALLAEYTGELASAAADAK 137 Query 126 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADA 185 VDLYFEAAVAGAIPVIRPL QSLAGDTV RVAGIVNGTTN+ILSAMD TGADYA LA+A Sbjct 138 VDLYFEAAVAGAIPVIRPLMQSLAGDTVERVAGIVNGTTNFILSAMDETGADYADTLAEA 197 Query 186 SALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALG 245 LGYAEADPTADVEGYDAAAKAAILASIAFH+RVTA DV+REGI+ VT AD +A Sbjct 198 GRLGYAEADPTADVEGYDAAAKAAILASIAFHSRVTAADVHREGISSVTAADLLAAKKFD 257 Query 246 CTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYG 305 CTIKLLSICER+ +GSQRVSARVYPAL+PL+HPLA VNGAFNAVVVEAE AGRLMFYG Sbjct 258 CTIKLLSICERVRDVDGSQRVSARVYPALIPLTHPLATVNGAFNAVVVEAENAGRLMFYG 317 Query 306 QGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKP 365 QGAGG+PTASAV GD+VMAARNRV G RGP ES YA LP+AP+ + TRYY+SM VAD+P Sbjct 318 QGAGGSPTASAVLGDMVMAARNRVHGGRGPLESTYASLPIAPIDDVFTRYYISMRVADRP 377 Query 366 GVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLD 425 GVL+ VA EF KR VSIA VRQEG D+ AR++VVTH A D A S+ V AL+D+D Sbjct 378 GVLAQVAGEFTKRSVSIAAVRQEGAGDD------ARLIVVTHRAPDRAQSDCVAALEDMD 431 Query 426 VVQGVSSVIRLEGT 439 V VSSV+RLEGT Sbjct 432 AVIKVSSVLRLEGT 445 >gi|54023016|ref|YP_117258.1| homoserine dehydrogenase [Nocardia farcinica IFM 10152] gi|54014524|dbj|BAD55894.1| putative homoserine dehydrogenase [Nocardia farcinica IFM 10152] Length=451 Score = 550 bits (1416), Expect = 2e-154, Method: Compositional matrix adjust. Identities = 298/445 (67%), Positives = 356/445 (80%), Gaps = 14/445 (3%) Query 3 GDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELL 62 G ++P+GVAVLG+GNVG+EVVRI+ +DL ARVGAP+VLRG+ VR + DRG+P +LL Sbjct 11 GADRPIGVAVLGMGNVGTEVVRILREHTDDLRARVGAPVVLRGVAVRNLDKDRGLPADLL 70 Query 63 TDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAE 122 T D E LVAR DVD+VVEV+G ++P+R IL AL GKSVVTANKALLA TGELA AAE Sbjct 71 TTDAEGLVARPDVDLVVEVIGGIDPARALILAALNAGKSVVTANKALLADYTGELAAAAE 130 Query 123 SAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASAL 182 DLYFEAAVAGAIPV+RPL QSL+GD V RV GIVNGTTN+ILSAMD TGADY++ L Sbjct 131 RNRADLYFEAAVAGAIPVVRPLIQSLSGDRVNRVVGIVNGTTNFILSAMDETGADYSATL 190 Query 183 ADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAH 242 A+A+ LGYAEADPTADVEGYDAAAKAAILAS+AFHTRVTA DVYREGI+++T D +A Sbjct 191 AEATRLGYAEADPTADVEGYDAAAKAAILASLAFHTRVTAADVYREGISRITAEDLETAS 250 Query 243 ALGCTIKLLSICERIT--------TDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVE 294 A+ CT+KLL+ICER+ + G +RVS RVYPAL+P HPLAAV+GAFNAVVVE Sbjct 251 AVNCTVKLLAICERVAAGPGEPSPAEGGKERVSVRVYPALIPRKHPLAAVSGAFNAVVVE 310 Query 295 AEAAGRLMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETR 354 AE AGRLMFYGQGAGGAPTASAV GDLVMAARN+ G R P ES YA+LP+AP+G TR Sbjct 311 AENAGRLMFYGQGAGGAPTASAVLGDLVMAARNKFYGGRAPGESVYAELPIAPIGDTPTR 370 Query 355 YYVSMNVADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAAL 414 Y+V++ V D+PGVL+ VA EFAK EVSI+ VRQEG + GAR+VVVTH A ++AL Sbjct 371 YHVNLQVEDRPGVLAKVAGEFAKHEVSISTVRQEGHGE------GARLVVVTHHAMESAL 424 Query 415 SETVDALDDLDVVQGVSSVIRLEGT 439 ++TV AL +++ V V+SV+RLEGT Sbjct 425 ADTVAALAEMESVTSVTSVLRLEGT 449 >gi|296138957|ref|YP_003646200.1| homoserine dehydrogenase [Tsukamurella paurometabola DSM 20162] gi|296027091|gb|ADG77861.1| Homoserine dehydrogenase [Tsukamurella paurometabola DSM 20162] Length=438 Score = 543 bits (1398), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 301/435 (70%), Positives = 345/435 (80%), Gaps = 4/435 (0%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDD 65 + +GVA+LG+G VG+EV RI+ ++A+DLAARVGA LV+RGI VR DRGV LLT D Sbjct 7 RELGVALLGMGTVGTEVARILIDNADDLAARVGARLVIRGIAVRDTDKDRGVDPALLTGD 66 Query 66 IEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAH 125 E L+ R+DVDIVVEVMG +EP+R +L AL+ GKSVVTANKALLA TGELA AA A Sbjct 67 AEALIDRDDVDIVVEVMGGIEPTRTHMLRALQAGKSVVTANKALLAEYTGELADAANRAR 126 Query 126 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADA 185 DLYFEAAVAGAIPVIRPL QSLAGDTV VAGIVNGTTN+ILS M G Y + LA+A Sbjct 127 ADLYFEAAVAGAIPVIRPLQQSLAGDTVELVAGIVNGTTNFILSNMAEKGEAYETVLAEA 186 Query 186 SALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALG 245 LGYAEADPTADVEGYDAA+KAAILASIAFHTRV ADDVYREGIT V+ AD +A A Sbjct 187 GRLGYAEADPTADVEGYDAASKAAILASIAFHTRVKADDVYREGITAVSAADIEAAKAFD 246 Query 246 CTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYG 305 CTIKLL+ICER T G QRVSARVYPALVPL HPLA+V+GA+NAV VEAE AGRLMFYG Sbjct 247 CTIKLLAICERFTDAAGEQRVSARVYPALVPLKHPLASVDGAYNAVFVEAENAGRLMFYG 306 Query 306 QGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKP 365 GAGGAPTASAV GDLV AARN+V RGP +S YA LP+AP+G + TRYYV+M V+D+P Sbjct 307 AGAGGAPTASAVMGDLVAAARNKVFSGRGPLDSVYANLPIAPIGDVLTRYYVAMEVSDRP 366 Query 366 GVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLD 425 GVLSAVA EF+ R VSI+ VRQ+ + GAR+V++TH A DAALS TV+AL +LD Sbjct 367 GVLSAVANEFSARNVSISTVRQQADLPSS----GARLVILTHKAPDAALSATVEALKNLD 422 Query 426 VVQGVSSVIRLEGTG 440 VV VSSV+RLEGT Sbjct 423 VVTAVSSVLRLEGTN 437 >gi|333920934|ref|YP_004494515.1| Homoserine dehydrogenase [Amycolicicoccus subflavus DQS3-9A1] gi|333483155|gb|AEF41715.1| Homoserine dehydrogenase [Amycolicicoccus subflavus DQS3-9A1] Length=443 Score = 540 bits (1391), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 307/435 (71%), Positives = 348/435 (80%), Gaps = 6/435 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 E+ +G+AVLGLGNVGSEVVR++ A++L ARVGA L ++GI VR V+ DRGVP+ELLTD Sbjct 12 ERTLGIAVLGLGNVGSEVVRLLTAHADELQARVGARLEIKGIAVRNVSPDRGVPVELLTD 71 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV+R+DVDIVVEV G +EP R IL AL GKSVVTANKALLA TGELA A++A Sbjct 72 DPAALVSRDDVDIVVEVFGGIEPVRTLILNALNSGKSVVTANKALLADYTGELAAVADAA 131 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 +DLYFEAAVAGAIPV+RPL QSLAGD V RV GIVNGTTN+ILSAM TGADYA LA+ Sbjct 132 DLDLYFEAAVAGAIPVVRPLMQSLAGDRVKRVVGIVNGTTNFILSAMGETGADYAETLAE 191 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 AS LGYAEADPTADVEG+DAAAKAAILASIAFHTRVTA DVYREGI++++ D SA L Sbjct 192 ASRLGYAEADPTADVEGFDAAAKAAILASIAFHTRVTASDVYREGISEISAEDLASAADL 251 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 CTIKLL+ICER+T D G +RVSARVYPAL+P HPL+AVNGAFNAVVVEAEAAGRLMFY Sbjct 252 DCTIKLLAICERVTDDTGRERVSARVYPALLPNVHPLSAVNGAFNAVVVEAEAAGRLMFY 311 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLV AARN+V G +GP ES YA+LPV +G TRYYV M VAD+ Sbjct 312 GQGAGGAPTASAVLGDLVSAARNKVHGGKGPDESTYAKLPVMSIGDTPTRYYVRMEVADR 371 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 GVL+AVA EFA VSI+ VRQ G+ D A +VVVTH A D ALS+TV AL Sbjct 372 TGVLAAVAQEFANHGVSISTVRQSGLAD------AATLVVVTHRAPDDALSKTVAALTSR 425 Query 425 DVVQGVSSVIRLEGT 439 D V V+SVIRLEGT Sbjct 426 DFVNTVTSVIRLEGT 440 >gi|319948888|ref|ZP_08023000.1| homoserine dehydrogenase [Dietzia cinnamea P4] gi|319437447|gb|EFV92455.1| homoserine dehydrogenase [Dietzia cinnamea P4] Length=450 Score = 535 bits (1377), Expect = 9e-150, Method: Compositional matrix adjust. Identities = 298/437 (69%), Positives = 346/437 (80%), Gaps = 4/437 (0%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDD 65 +PVGVAVLG+G VG+EV+R + +AE LAAR+GAPLVLRG+ VR +T DRG+ +LLT D Sbjct 10 RPVGVAVLGMGTVGTEVIRYMTENAEALAARIGAPLVLRGVAVRDLTKDRGLDPDLLTAD 69 Query 66 IEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAH 125 LV+REDVDIVVE+MG ++ R +L AL GK+VVTANKALLA T ELA+AA+S H Sbjct 70 PASLVSREDVDIVVELMGGIDLPRPLLLEALRHGKAVVTANKALLAEYTDELAEAADSTH 129 Query 126 VDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADA 185 DLYFEAAVAGAIPVI PL +S+AGD V RV GIVNGTTNYILS M STGADY+ LA+A Sbjct 130 TDLYFEAAVAGAIPVIGPLRRSMAGDQVERVVGIVNGTTNYILSEMGSTGADYSETLAEA 189 Query 186 SALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALG 245 S LGYAEADPTADVEGYDAAAKAAILASIAFH+RVTA DVYREGI++++P DF SA + Sbjct 190 SRLGYAEADPTADVEGYDAAAKAAILASIAFHSRVTAGDVYREGISRISPDDFESARDMD 249 Query 246 CTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYG 305 CTIKLL+ICE++ +GS+ VSARVYPAL+P SHPLAAVNGAFNAVVVEA+AAGRLMFYG Sbjct 250 CTIKLLAICEKLRQSDGSEAVSARVYPALLPNSHPLAAVNGAFNAVVVEAQAAGRLMFYG 309 Query 306 QGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKP 365 QGAGGAPTASAV GD+V AARN+ R P ES YA LPVA M I TRY+V M VADKP Sbjct 310 QGAGGAPTASAVLGDMVAAARNKAGAGRAPGESTYAALPVANMDEISTRYHVRMRVADKP 369 Query 366 GVLSAVAAEFAKREVSIAEVRQE--GVVDEGGRRV--GARIVVVTHLATDAALSETVDAL 421 GVL+ VA EF+ VSIA+VRQ V D V A I V+THLAT+ AL++TV AL Sbjct 370 GVLAQVATEFSTHGVSIAQVRQTEVEVPDAEAEDVEPTAEITVLTHLATERALADTVAAL 429 Query 422 DDLDVVQGVSSVIRLEG 438 D D V ++SVIRLEG Sbjct 430 SDQDAVTAITSVIRLEG 446 >gi|257056969|ref|YP_003134801.1| homoserine dehydrogenase [Saccharomonospora viridis DSM 43017] gi|256586841|gb|ACU97974.1| homoserine dehydrogenase [Saccharomonospora viridis DSM 43017] Length=435 Score = 519 bits (1336), Expect = 4e-145, Method: Compositional matrix adjust. Identities = 280/434 (65%), Positives = 335/434 (78%), Gaps = 7/434 (1%) Query 5 EKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTD 64 E PV VA+LG G VGSEV R++ N A++LAARVGAP+ L GI VRR +P +LLT Sbjct 6 ESPVRVALLGCGTVGSEVARLLLNGADELAARVGAPVELAGIAVRRPDKHPELPQQLLTA 65 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D ELV DVDIVVE++G +EP R +L AL +GKSVVT NKALLA GEL++AA + Sbjct 66 DAGELV-ESDVDIVVELIGGIEPVRGWLLTALRQGKSVVTGNKALLAEHGGELSEAANDS 124 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EA+VAGAIP++RPL +SLAGD + RV GIVNGTTN+ILSAMDSTGA YA L + Sbjct 125 GADLYYEASVAGAIPLLRPLRESLAGDRITRVMGIVNGTTNFILSAMDSTGASYAETLEE 184 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ LGYAEADP+ADVEGYDAA+KAAILAS+AFHTRVTA DVYREGI +T +D +A L Sbjct 185 ATRLGYAEADPSADVEGYDAASKAAILASLAFHTRVTASDVYREGIVGITASDIAAAKRL 244 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 T+KLL+ICER+T ++G++ VSARV+P ++P +H LA V GAFNAV VEAEAAG LMFY Sbjct 245 NRTVKLLAICERVTDEDGTESVSARVHPVMIPRTHQLAGVGGAFNAVYVEAEAAGELMFY 304 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 GQGAGGAPTASAV GDLV AARNRV G RGPRES +A LPV PMG TRY++S++VAD+ Sbjct 305 GQGAGGAPTASAVLGDLVAAARNRVAGGRGPRESAHAALPVRPMGQTPTRYHISLDVADR 364 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA VSIA VRQ DE R AR+VVVTHLA DAAL TV+ + L Sbjct 365 PGVLAQVAQVFAAHGVSIAAVRQR---DE---RSTARLVVVTHLAPDAALEATVNEISKL 418 Query 425 DVVQGVSSVIRLEG 438 DVV+ V SV+R+EG Sbjct 419 DVVREVLSVMRVEG 432 >gi|229490020|ref|ZP_04383873.1| homoserine dehydrogenase [Rhodococcus erythropolis SK121] gi|229323121|gb|EEN88889.1| homoserine dehydrogenase [Rhodococcus erythropolis SK121] Length=358 Score = 515 bits (1326), Expect = 7e-144, Method: Compositional matrix adjust. Identities = 282/362 (78%), Positives = 308/362 (86%), Gaps = 6/362 (1%) Query 78 VVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHVDLYFEAAVAGA 137 +VEV+G +E RK IL +L GKSVVTANKALLA TGELA+AAE+ VDLYFEAAVAGA Sbjct 1 MVEVIGGIELPRKLILSSLNSGKSVVTANKALLADHTGELAEAAEANSVDLYFEAAVAGA 60 Query 138 IPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADASALGYAEADPTA 197 IPVIRPLTQSLAGD V +VAGIVNGTTN+ILSAMD TGADY LA+A LGYAEADPTA Sbjct 61 IPVIRPLTQSLAGDRVNKVAGIVNGTTNFILSAMDETGADYEETLAEAGRLGYAEADPTA 120 Query 198 DVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGCTIKLLSICERI 257 DVEGYDAAAKAAILASIAFHTRVTA DVYREGI+ +T AD SA AL CTIKLLSICERI Sbjct 121 DVEGYDAAAKAAILASIAFHTRVTAADVYREGISTITSADLASAKALDCTIKLLSICERI 180 Query 258 TTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQGAGGAPTASAV 317 T +G +R+SARVYPALVPLSHPLA+VNGAFNAVVVEAE AGRLMFYGQGAGGAPTASAV Sbjct 181 VTPKGKERISARVYPALVPLSHPLASVNGAFNAVVVEAENAGRLMFYGQGAGGAPTASAV 240 Query 318 TGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPGVLSAVAAEFAK 377 GDLVMAARN+V G RGPRESKYA+L VAPMG I TRYYV+M VADK GVLSAVAAEFAK Sbjct 241 MGDLVMAARNKVHGGRGPRESKYAKLKVAPMGDILTRYYVNMEVADKEGVLSAVAAEFAK 300 Query 378 REVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDVVQGVSSVIRLE 437 VSI+ VRQEG GAR+VVVTH+ATDAALSETV AL++L+ V V+SV+RLE Sbjct 301 HGVSISVVRQEGA------GAGARLVVVTHVATDAALSETVAALNELEFVTAVTSVLRLE 354 Query 438 GT 439 GT Sbjct 355 GT 356 >gi|254231552|ref|ZP_04924879.1| homoserine dehydrogenase thrA [Mycobacterium tuberculosis C] gi|124600611|gb|EAY59621.1| homoserine dehydrogenase thrA [Mycobacterium tuberculosis C] Length=277 Score = 511 bits (1317), Expect = 8e-143, Method: Compositional matrix adjust. Identities = 262/264 (99%), Positives = 263/264 (99%), Gaps = 0/264 (0%) Query 1 VPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 +PGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE Sbjct 1 MPGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIE 60 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA Sbjct 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS Sbjct 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS Sbjct 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 Query 241 AHALGCTIKLLSICERITTDEGSQ 264 AHALGCTIKLLSICERITTDEGS Sbjct 241 AHALGCTIKLLSICERITTDEGSH 264 >gi|302529807|ref|ZP_07282149.1| homoserine dehydrogenase [Streptomyces sp. AA4] gi|302438702|gb|EFL10518.1| homoserine dehydrogenase [Streptomyces sp. AA4] Length=444 Score = 509 bits (1312), Expect = 2e-142, Method: Compositional matrix adjust. Identities = 279/437 (64%), Positives = 333/437 (77%), Gaps = 6/437 (1%) Query 2 PGDEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIEL 61 P D P+ VA+LG G VGSEV R++ A +LAAR GAP+ L GI VRR +P EL Sbjct 11 PADRAPIRVAMLGCGTVGSEVARLLTEQAGELAARAGAPVELVGIAVRRPDKHPELPAEL 70 Query 62 LTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAA 121 LTDD LVAR+DVD+VVE++G ++P R +L AL GKSVVTANKALLA + EL +A+ Sbjct 71 LTDDAAALVARDDVDVVVELVGGIDPVRSWLLTALNAGKSVVTANKALLAEYSAELFEAS 130 Query 122 ESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASA 181 +++ DLYFEAAVAGAIP++RPL +SLAGD + RV GIVNGTTNYILSAMD+TGA YA Sbjct 131 DASGADLYFEAAVAGAIPLLRPLRESLAGDRITRVMGIVNGTTNYILSAMDATGAGYAET 190 Query 182 LADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSA 241 L +AS LGYAEADPTADV+GYDAA+KAAILAS+AFH+RVTA DV+REGI VT +D +A Sbjct 191 LDEASRLGYAEADPTADVDGYDAASKAAILASLAFHSRVTAKDVHREGIADVTASDLAAA 250 Query 242 HALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRL 301 LG T+KLL+ICER+T D+G++ VSARV+P ++P SH LA V GAFNAV VEA+AAG L Sbjct 251 RTLGRTVKLLAICERVTADDGTESVSARVHPVMIPRSHQLAGVGGAFNAVYVEADAAGEL 310 Query 302 MFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNV 361 MFYGQGAGGAPTASAV GDLV ARN+VLG RGPRES +A LPV PMG TRY+VS++V Sbjct 311 MFYGQGAGGAPTASAVLGDLVAVARNQVLGGRGPRESAHAALPVRPMGQTPTRYHVSLDV 370 Query 362 ADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDAL 421 AD+ GVL+ VA FA VSIA VRQ D A +VVVTHLA DAAL TVD + Sbjct 371 ADRAGVLAQVAQAFAAHGVSIAAVRQRDANDT------ASLVVVTHLAPDAALQSTVDEI 424 Query 422 DDLDVVQGVSSVIRLEG 438 LDVV V SV+R+EG Sbjct 425 AKLDVVHEVVSVMRVEG 441 >gi|256380149|ref|YP_003103809.1| homoserine dehydrogenase [Actinosynnema mirum DSM 43827] gi|255924452|gb|ACU39963.1| Homoserine dehydrogenase [Actinosynnema mirum DSM 43827] Length=437 Score = 504 bits (1298), Expect = 1e-140, Method: Compositional matrix adjust. Identities = 276/435 (64%), Positives = 334/435 (77%), Gaps = 8/435 (1%) Query 4 DEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLT 63 D KP+ VA+LG G VG+EV R++ A DL ARVGAP+ L GI VR+ R VP ELLT Sbjct 8 DGKPIRVALLGCGTVGTEVARLLTEQAADLTARVGAPVELVGIAVRKPNKHREVPSELLT 67 Query 64 DDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAES 123 D E LVA DVD+VVEV+G +EP+R +LGAL GKSVVTANKALLA +GEL AA++ Sbjct 68 TDAEALVA-SDVDVVVEVIGGIEPARSLLLGALNAGKSVVTANKALLAEHSGELFAAADA 126 Query 124 AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALA 183 + DLYFEAAVAGAIP++RPL +SLAGD + RV GIVNGTTN+ILS MD+TGA Y L Sbjct 127 SGADLYFEAAVAGAIPLLRPLRESLAGDRITRVMGIVNGTTNFILSGMDATGAGYNETLE 186 Query 184 DASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHA 243 +AS LGYAEADPTADV+G+DAA+KAAILAS+AFH+RVTA DV+REGI+ V+ AD +A Sbjct 187 EASRLGYAEADPTADVDGFDAASKAAILASLAFHSRVTAADVHREGISAVSAADIAAAKG 246 Query 244 LGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMF 303 LG T+KLL+ICER++ + + VS RV+PA++P SHPLA+V GAFNAV VEA+AAG +MF Sbjct 247 LGRTVKLLAICERVSHGD-EESVSVRVHPAMIPRSHPLASVGGAFNAVFVEADAAGEMMF 305 Query 304 YGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVAD 363 YGQGAGGAPTASAV GDLV ARNRV G GPRES YA LP PMG TRY++S++V D Sbjct 306 YGQGAGGAPTASAVLGDLVAVARNRVAGGHGPRESAYAALPARPMGQTPTRYHISLDVED 365 Query 364 KPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDD 423 KPGVL+ VAA FA+ VSIA VRQEG V + A +V+VTH ATDAAL TVD + Sbjct 366 KPGVLAQVAAVFAEHGVSIAAVRQEGRVAD------ASLVIVTHAATDAALRSTVDKVGG 419 Query 424 LDVVQGVSSVIRLEG 438 L +V+ V SV+R+EG Sbjct 420 LPIVRDVVSVMRVEG 434 >gi|300789614|ref|YP_003769905.1| homoserine dehydrogenase [Amycolatopsis mediterranei U32] gi|299799128|gb|ADJ49503.1| homoserine dehydrogenase [Amycolatopsis mediterranei U32] gi|340531270|gb|AEK46475.1| homoserine dehydrogenase [Amycolatopsis mediterranei S699] Length=441 Score = 502 bits (1293), Expect = 4e-140, Method: Compositional matrix adjust. Identities = 278/435 (64%), Positives = 330/435 (76%), Gaps = 6/435 (1%) Query 4 DEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLT 63 D +P+ VA+LG G VG EV R++ A +LAAR GAP+ L GI VRR +P ELLT Sbjct 10 DRRPIRVALLGCGTVGGEVARLLTEQAGELAARAGAPVELAGIAVRRPDKHPELPPELLT 69 Query 64 DDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAES 123 D E+LV +DVD+VVE++G +EP R +L AL+ GKSVVTANKALLA + +L +AA++ Sbjct 70 ADAEKLVTSDDVDVVVELVGGIEPVRGWLLAALKAGKSVVTANKALLAEHSADLFEAADA 129 Query 124 AHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALA 183 A DLYFEAAVAGAIP++RPL +SLAGD + RV GIVNGTTNYILSAMDSTGA YA L Sbjct 130 AGADLYFEAAVAGAIPLLRPLRESLAGDRITRVMGIVNGTTNYILSAMDSTGAGYAETLD 189 Query 184 DASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHA 243 +AS LGYAEADPTADV+GYDAA+KAAILAS+AFHTRVTA DV+REGI VT +D +A Sbjct 190 EASRLGYAEADPTADVDGYDAASKAAILASLAFHTRVTASDVHREGIADVTASDLAAARG 249 Query 244 LGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMF 303 LG T+KLL+ICER+T D+G + VSARV+P ++P H LA V GAFNAV VEA+AAG LMF Sbjct 250 LGRTVKLLAICERVTDDDGVESVSARVHPVMIPRRHQLAGVGGAFNAVYVEADAAGELMF 309 Query 304 YGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVAD 363 YGQGAGGAPTASAV GDLV ARNRV+G RGPRES +A LPV PMG TRY+VS++VAD Sbjct 310 YGQGAGGAPTASAVLGDLVAVARNRVVGGRGPRESAHAALPVRPMGQTPTRYHVSLSVAD 369 Query 364 KPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDD 423 + GVL+ VA FA VSIA VRQ V D A +VVVTH A DAAL TVD + Sbjct 370 RAGVLAQVAQAFADHGVSIAAVRQSDVGDR------ASLVVVTHQAPDAALQSTVDEIGR 423 Query 424 LDVVQGVSSVIRLEG 438 LDVV V SV+R+EG Sbjct 424 LDVVHEVVSVMRVEG 438 >gi|337768157|emb|CCB76870.1| Homoserine dehydrogenase [Streptomyces cattleya NRRL 8057] Length=447 Score = 494 bits (1273), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 281/445 (64%), Positives = 336/445 (76%), Gaps = 15/445 (3%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A DLAAR+GAP+ L GI VRR R GVP EL+T Sbjct 5 RPLKVALLGCGVVGSEVARIMTTQAADLAARIGAPVELAGIAVRRPDRVRQGVPAELITT 64 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+V+EV+G +EP+R I A E G VV+ANKALLA L A Sbjct 65 DATALVKRGDIDVVIEVVGGIEPARTLITTAFEHGAGVVSANKALLAADGATLHAKAAEH 124 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 VDLY+EAAVAGAIP+IRPL +SLAGD V RV GIVNGTTN+IL MD+TGA Y+ AL + Sbjct 125 GVDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDRMDATGAGYSEALDE 184 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRVT DDV+REG+T+VT AD SA + Sbjct 185 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVTIDDVHREGLTEVTAADIASARRM 244 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCT+KLL+ICER + D S V+ARV+PA++PLSHPLA+V A+NAV VEAEAAGRLMFY Sbjct 245 GCTVKLLAICER-SADGNS--VTARVHPAMIPLSHPLASVREAYNAVFVEAEAAGRLMFY 301 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV A RNR+ G+RG +S Y QLPV+PMG + TRY++S++VADK Sbjct 302 GPGAGGAPTASAVLGDLVAACRNRLAGTRGVGDSAYTQLPVSPMGEVVTRYHISLDVADK 361 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDE-----------GGRRVGARIVVVTHLATDAA 413 PGVL+ VA FA+ EVSI VRQ+G E GRR GA +VVVTH A DAA Sbjct 362 PGVLAQVATIFAEHEVSIDTVRQQGRESEEGGDEAASGKGAGRRAGASLVVVTHRAPDAA 421 Query 414 LSETVDALDDLDVVQGVSSVIRLEG 438 LS TV+AL LD V+GV+S++R+EG Sbjct 422 LSATVEALRKLDTVRGVASIMRVEG 446 >gi|290957372|ref|YP_003488554.1| homoserine dehydrogenase [Streptomyces scabiei 87.22] gi|260646898|emb|CBG69995.1| homoserine dehydrogenase [Streptomyces scabiei 87.22] Length=433 Score = 489 bits (1259), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 273/434 (63%), Positives = 335/434 (78%), Gaps = 7/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A+DLAAR+GAP+ L G+ VRR + R G+ L+T Sbjct 5 RPLKVALLGCGVVGSEVARIMTTHADDLAARIGAPVELAGVAVRRPSRVRTGIDPALVTT 64 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+VVEV+G +EP+R I A E G SVV+ANKALLA L A A Sbjct 65 DATALVKRGDIDVVVEVIGGIEPARTLITTAFEHGASVVSANKALLAQDGAALHAVANEA 124 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EAAVAGAIP+IRPL +SLAGD + RV GIVNGTTN+IL MDSTGA Y AL + Sbjct 125 GKDLYYEAAVAGAIPLIRPLRESLAGDKINRVMGIVNGTTNFILDKMDSTGAGYQEALDE 184 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFH+RV DDVYREG+T+VT ADF SA + Sbjct 185 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHSRVRLDDVYREGMTEVTSADFASAKNM 244 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER D GS V+ARV+PA++PL+HPLA+V GA+NAV VE++AAG+LMFY Sbjct 245 GCTIKLLAICER-AADGGS--VTARVHPAMIPLTHPLASVRGAYNAVFVESDAAGQLMFY 301 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV RNR+ G+ GP ES YA LPV+PMG + TRY++S++VADK Sbjct 302 GPGAGGAPTASAVLGDLVAVCRNRLAGATGPGESAYAALPVSPMGDVTTRYHISLDVADK 361 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA F++ VSI VRQ+G D GG A +VVVTH A+DA+LS TV+AL +L Sbjct 362 PGVLAQVATVFSEHGVSIDTVRQQGRQDGGGE---ASLVVVTHRASDASLSGTVEALRNL 418 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 419 DTVRGVASIMRVEG 432 >gi|325002814|ref|ZP_08123926.1| homoserine dehydrogenase [Pseudonocardia sp. P1] Length=468 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 278/446 (63%), Positives = 341/446 (77%), Gaps = 13/446 (2%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPI---ELLTD 64 V VA+LG G VG+EVVR+I A+DL ARVGAP+ L G+ VRR + L+T Sbjct 13 VRVALLGCGTVGTEVVRLITGQADDLTARVGAPVELVGVAVRRPHRHPWLHENFGHLVTT 72 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D ELV R+DVD+VVEV+G +EP R +L AL+ GKSVVTANKALLA LA+AA+++ Sbjct 73 DASELVTRDDVDVVVEVIGGIEPVRGWLLEALKAGKSVVTANKALLAEDGPTLAEAADAS 132 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EAAVAGAIP++RPL +SLAGD + RVAGIVNGT+N+ILSAM + G YA AL + Sbjct 133 GADLYYEAAVAGAIPLLRPLRESLAGDRITRVAGIVNGTSNFILSAMSAGGTSYADALEE 192 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ LGYAEADP+ADV+GYDAA+KAAILA++AFHTR+TA DV+REG+ +V+ AD +A L Sbjct 193 ATRLGYAEADPSADVDGYDAASKAAILATLAFHTRITASDVHREGMREVSSADVAAARRL 252 Query 245 GCTIKLLSICERI--TTDEG--SQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 GCTIKLL+ICER+ T +G ++ VSARVYPA+VP SHPLA V+GAFNAV VEAEAAG+ Sbjct 253 GCTIKLLAICERVVDTAADGTATESVSARVYPAMVPESHPLARVDGAFNAVFVEAEAAGQ 312 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTASAV GDLV ARNRV G RGPRES YA LPV P+G + TRY+V + Sbjct 313 LMFYGQGAGGAPTASAVLGDLVAVARNRVGGGRGPRESAYASLPVRPVGEVPTRYHVDLE 372 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVD------EGGRRVGARIVVVTHLATDAAL 414 VAD+ GVL+A+A EFA+ VSIA VRQ G V+ +G R AR+ VVTH A +AAL Sbjct 373 VADREGVLAAIAGEFARHGVSIAAVRQTGGVNGSVDRPDGSDRSQARLTVVTHSAPEAAL 432 Query 415 SETVDALDDLDVVQGVSSVIRLEGTG 440 + TV AL DLD V GV+ V+R+EG G Sbjct 433 AATVSALLDLDHVLGVAGVLRVEGLG 458 >gi|254387530|ref|ZP_05002769.1| homoserine dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|197701256|gb|EDY47068.1| homoserine dehydrogenase [Streptomyces clavuligerus ATCC 27064] Length=432 Score = 486 bits (1252), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 271/434 (63%), Positives = 330/434 (77%), Gaps = 7/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A+DLAAR+GAP+ L G+ VRR + R G+P EL+T Sbjct 4 RPLKVALLGCGVVGSEVARIMTTHADDLAARIGAPVELAGVAVRRPSKVRAGIPQELITT 63 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+V+EV+G +EP+R I A E G SVV+ANKALLA L AAE Sbjct 64 DATALVKRGDIDVVIEVIGGIEPARTLITTAFEHGASVVSANKALLAEDGATLYAAAERH 123 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLYFEAAVAGAIP+IRPL +SLAGD V RV GIVNGTTN+IL MDS+GA Y AL + Sbjct 124 GRDLYFEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDRMDSSGAGYTEALDE 183 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRV DDV+REG+T+VT AD SA + Sbjct 184 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVHREGLTEVTAADMASARRM 243 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCT+KLL+ICER + V+ARV+PA++PLSHPLA+V A+NAV VE+EAAG+LMFY Sbjct 244 GCTVKLLAICERAAD---GRSVTARVHPAMIPLSHPLASVREAYNAVFVESEAAGQLMFY 300 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV RN++ G+ GP ES Y QLPV+PMG + TRY++S++VADK Sbjct 301 GPGAGGAPTASAVLGDLVAVCRNKLAGATGPGESAYTQLPVSPMGEVVTRYHISLDVADK 360 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA+ VSI VRQ+G D G A +VVVTH A DAAL TV+AL L Sbjct 361 PGVLAQVATVFAEHGVSIDTVRQQGRQDSSGE---ASLVVVTHRAPDAALQGTVEALRSL 417 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 418 DTVRGVASIMRVEG 431 >gi|294815082|ref|ZP_06773725.1| Homoserine dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|326443445|ref|ZP_08218179.1| homoserine dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|294327681|gb|EFG09324.1| Homoserine dehydrogenase [Streptomyces clavuligerus ATCC 27064] Length=433 Score = 486 bits (1251), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 271/434 (63%), Positives = 330/434 (77%), Gaps = 7/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A+DLAAR+GAP+ L G+ VRR + R G+P EL+T Sbjct 5 RPLKVALLGCGVVGSEVARIMTTHADDLAARIGAPVELAGVAVRRPSKVRAGIPQELITT 64 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+V+EV+G +EP+R I A E G SVV+ANKALLA L AAE Sbjct 65 DATALVKRGDIDVVIEVIGGIEPARTLITTAFEHGASVVSANKALLAEDGATLYAAAERH 124 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLYFEAAVAGAIP+IRPL +SLAGD V RV GIVNGTTN+IL MDS+GA Y AL + Sbjct 125 GRDLYFEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDRMDSSGAGYTEALDE 184 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRV DDV+REG+T+VT AD SA + Sbjct 185 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVHREGLTEVTAADMASARRM 244 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCT+KLL+ICER + V+ARV+PA++PLSHPLA+V A+NAV VE+EAAG+LMFY Sbjct 245 GCTVKLLAICERAAD---GRSVTARVHPAMIPLSHPLASVREAYNAVFVESEAAGQLMFY 301 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV RN++ G+ GP ES Y QLPV+PMG + TRY++S++VADK Sbjct 302 GPGAGGAPTASAVLGDLVAVCRNKLAGATGPGESAYTQLPVSPMGEVVTRYHISLDVADK 361 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA+ VSI VRQ+G D G A +VVVTH A DAAL TV+AL L Sbjct 362 PGVLAQVATVFAEHGVSIDTVRQQGRQDSSGE---ASLVVVTHRAPDAALQGTVEALRSL 418 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 419 DTVRGVASIMRVEG 432 >gi|296393111|ref|YP_003657995.1| homoserine dehydrogenase [Segniliparus rotundus DSM 44985] gi|296180258|gb|ADG97164.1| Homoserine dehydrogenase [Segniliparus rotundus DSM 44985] Length=471 Score = 485 bits (1249), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 276/458 (61%), Positives = 333/458 (73%), Gaps = 24/458 (5%) Query 4 DEKPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIEL-- 61 +++ +GV +LGLG VGSEV R++ AE+LAARVGA LVLRG+ VR++ RGV L Sbjct 10 EKREIGVGLLGLGTVGSEVARVLVEDAEELAARVGAKLVLRGVAVRKLDAPRGVCEHLVD 69 Query 62 ---LTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELA 118 LT D ELVAR+DVD+VVE++G + P++ I AL GKSVV+ANKAL A + +L Sbjct 70 PALLTTDAAELVARDDVDVVVELIGGINPAKDLIRQALRAGKSVVSANKALFAAHSAKLF 129 Query 119 QAAESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADY 178 +AA+ A VDL+FEAAVAGAIPVIRPL QSLAGD + VAGIVNGTTN+ILSAMDS G DY Sbjct 130 EAAQKAKVDLFFEAAVAGAIPVIRPLRQSLAGDRITTVAGIVNGTTNFILSAMDSKGDDY 189 Query 179 ASALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADF 238 L +A LGYAEADPTADV G+DAAAK AI+ASIAFHTRVTADDV+ EGIT + AD Sbjct 190 DKVLREAQELGYAEADPTADVGGHDAAAKTAIMASIAFHTRVTADDVHVEGITDIAAADV 249 Query 239 GSAHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAA 298 SA LG TIKLLS+ ER+T +G +RVSARVYPALVP SHPLA+VNGA+NAVVVEA A Sbjct 250 ESAKQLGYTIKLLSMSERVTGGDGHERVSARVYPALVPRSHPLASVNGAYNAVVVEAVNA 309 Query 299 GRLMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVS 358 GRLMFYGQGAGGAPTAS+V GDLV AARN VLG ES YA+LP+AP+ + RY+V Sbjct 310 GRLMFYGQGAGGAPTASSVAGDLVAAARNLVLGRAVASESTYAKLPIAPISDVAARYFVR 369 Query 359 MNVADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRV-------------------G 399 + V D+PGVL++VAA FAKR+VSIA V Q+G+ +GG G Sbjct 370 IRVDDRPGVLASVAAVFAKRDVSIATVLQKGLPRDGGHDASGGSDASAQSESAADGASGG 429 Query 400 ARIVVVTHLATDAALSETVDALDDLDVVQGVSSVIRLE 437 A I+++TH A ALSETV ++ V V SV+RLE Sbjct 430 AEIIIITHSALGGALSETVREVEGHPAVVEVESVLRLE 467 >gi|329939820|ref|ZP_08289121.1| homoserine dehydrogenase [Streptomyces griseoaurantiacus M045] gi|329301390|gb|EGG45285.1| homoserine dehydrogenase [Streptomyces griseoaurantiacus M045] Length=433 Score = 484 bits (1246), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 275/434 (64%), Positives = 329/434 (76%), Gaps = 7/434 (1%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ AEDLAAR+GAPL L G+ VRR R G+ L+T Sbjct 5 RPLKVALLGCGVVGSEVARIMTTHAEDLAARIGAPLELAGVAVRRPAKVRAGIDPALVTT 64 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+VVEV+G +EP+R I ALE G SVV+ANKALLA L AA Sbjct 65 DATALVKRGDIDVVVEVIGGIEPARSLITTALEHGASVVSANKALLAQDGAALHAAAGEH 124 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EAAVAGAIP+IRPL +SLAGD V RV GIVNGTTN+IL MDSTGA Y AL + Sbjct 125 GRDLYYEAAVAGAIPLIRPLRESLAGDKVDRVLGIVNGTTNFILDKMDSTGAGYQEALDE 184 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRV DDVYREG+T+VT ADF SA + Sbjct 185 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADFASAKEM 244 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER E V+ARV+PA++PLSHPLA+V GA+NAV VE+EAAG+LMFY Sbjct 245 GCTIKLLAICERAADGES---VTARVHPAMIPLSHPLASVRGAYNAVFVESEAAGQLMFY 301 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV RNR+ G+ GP ES Y +LPV+PMG + TRY++S++VADK Sbjct 302 GPGAGGAPTASAVLGDLVAVCRNRLNGTTGPGESAYTRLPVSPMGEVVTRYHISLDVADK 361 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA+ VSI VRQ+ D G A +VVVTH A+DAAL+ V+AL L Sbjct 362 PGVLAQVATVFAEHGVSIDTVRQQSRPDGDGE---ASLVVVTHRASDAALTGVVEALRSL 418 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 419 DTVRGVASIMRVEG 432 >gi|19552407|ref|NP_600409.1| homoserine dehydrogenase [Corynebacterium glutamicum ATCC 13032] gi|62390071|ref|YP_225473.1| homoserine dehydrogenase [Corynebacterium glutamicum ATCC 13032] gi|145295322|ref|YP_001138143.1| homoserine dehydrogenase [Corynebacterium glutamicum R] 7 more sequence titles Length=445 Score = 483 bits (1242), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 262/431 (61%), Positives = 332/431 (78%), Gaps = 7/431 (1%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTDDI 66 VG+A+LG G VG+EV+R++ ++LA R+G PL +RGI V ++ R GV ELLT+D Sbjct 19 VGIALLGFGTVGTEVMRLMTEYGDELAHRIGGPLEVRGIAVSDISKPREGVAPELLTEDA 78 Query 67 EELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHV 126 L+ REDVDIVVEV+G +E R+ +L AL+ GKSVVTANKAL+A + ELA AAE+A+V Sbjct 79 FALIEREDVDIVVEVIGGIEYPREVVLAALKAGKSVVTANKALVAAHSAELADAAEAANV 138 Query 127 DLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADAS 186 DLYFEAAVAGAIPV+ PL +SLAGD + V GIVNGTTN+IL AMDSTGADYA +LA+A+ Sbjct 139 DLYFEAAVAGAIPVVGPLRRSLAGDQIQSVMGIVNGTTNFILDAMDSTGADYADSLAEAT 198 Query 187 ALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGC 246 LGYAEADPTADVEG+DAA+KAAILASIAFHTRVTADDVY EGI+ ++ AD +A G Sbjct 199 RLGYAEADPTADVEGHDAASKAAILASIAFHTRVTADDVYCEGISNISAADIEAAQQAGH 258 Query 247 TIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQ 306 TIKLL+ICE+ T EG +SARV+P L+P+SHPLA+VN +FNA+ VEAEAAGRLMFYG Sbjct 259 TIKLLAICEKFTNKEGKSAISARVHPTLLPVSHPLASVNKSFNAIFVEAEAAGRLMFYGN 318 Query 307 GAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPG 366 GAGGAPTASAV GD+V AARN+V G R P ES YA LP+A G TRY++ M+V D+ G Sbjct 319 GAGGAPTASAVLGDVVGAARNKVHGGRAPGESTYANLPIADFGETTTRYHLDMDVEDRVG 378 Query 367 VLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDV 426 VL+ +A+ F+++ +S+ +RQE D+ AR++VVTH A ++ LS TV+ L V Sbjct 379 VLAELASLFSEQGISLRTIRQEERDDD------ARLIVVTHSALESDLSRTVELLKAKPV 432 Query 427 VQGVSSVIRLE 437 V+ ++SVIRLE Sbjct 433 VKAINSVIRLE 443 >gi|302554158|ref|ZP_07306500.1| homoserine dehydrogenase [Streptomyces viridochromogenes DSM 40736] gi|302471776|gb|EFL34869.1| homoserine dehydrogenase [Streptomyces viridochromogenes DSM 40736] Length=429 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 272/434 (63%), Positives = 331/434 (77%), Gaps = 10/434 (2%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A+DL AR+GAP+ L G+ VRR R G+ EL+T Sbjct 4 RPLKVALLGCGVVGSEVARIMTTHADDLTARIGAPVELAGVAVRRPDRVREGIAPELVTT 63 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+D+VVEV+G +EP+R I A E G SVV+ANKALLA L AA+ Sbjct 64 DATALVKRGDIDVVVEVIGGIEPARTLITTAFEHGASVVSANKALLAQDGAALHAAADEH 123 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EAAVAGAIP+IRPL +SLAGD + RV GIVNGTTN+IL MDSTGA Y AL + Sbjct 124 DKDLYYEAAVAGAIPLIRPLRESLAGDKINRVMGIVNGTTNFILDKMDSTGAGYQEALDE 183 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRV DDVYREG+T+VT +DF SA + Sbjct 184 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTASDFASAKEM 243 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER D GS V+ARV+PA++PLSHPLA+V GA+NAV VE++AAG+LMFY Sbjct 244 GCTIKLLAICER-AADGGS--VTARVHPAMIPLSHPLASVRGAYNAVFVESDAAGQLMFY 300 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGG+PTASAV GDLV RNR+ G+ GP ES YA LPV+PMG + TRY++S++VADK Sbjct 301 GPGAGGSPTASAVLGDLVAVCRNRIGGATGPGESAYAALPVSPMGDVVTRYHISLDVADK 360 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA+ VSI VRQ G E A +VVVTH A+DAAL+ TV+AL L Sbjct 361 PGVLAQVATVFAEHGVSIDTVRQSGKDGE------ASLVVVTHRASDAALTGTVEALRKL 414 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 415 DTVRGVASIMRVEG 428 >gi|291437227|ref|ZP_06576617.1| homoserine dehydrogenase [Streptomyces ghanaensis ATCC 14672] gi|291340122|gb|EFE67078.1| homoserine dehydrogenase [Streptomyces ghanaensis ATCC 14672] Length=429 Score = 481 bits (1237), Expect = 1e-133, Method: Compositional matrix adjust. Identities = 275/434 (64%), Positives = 332/434 (77%), Gaps = 10/434 (2%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTD 64 +P+ VA+LG G VGSEV RI+ A+DLAAR+GAP+ L G+ VRR R GVP EL+T Sbjct 4 RPLKVALLGCGVVGSEVARIMTTHADDLAARIGAPVELAGVAVRRPDKVREGVPAELVTT 63 Query 65 DIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESA 124 D LV R D+DIVVEV+G +EP+R I A + G SVV+ANKALLA L AAE+ Sbjct 64 DATALVKRGDLDIVVEVIGGIEPARTLITTAFQHGASVVSANKALLAQDGAALHAAAEAH 123 Query 125 HVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALAD 184 DLY+EAAVAGAIP+IRPL +SLAGD V RV GIVNGTTN+IL MD+TGA Y AL + Sbjct 124 GKDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDKMDTTGAGYQEALDE 183 Query 185 ASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHAL 244 A+ALGYAEADPTADVEG+DAAAKAAILA IAFHTRV DDV+REG+T+VT ADF SA + Sbjct 184 ATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVHREGMTEVTAADFASAKEM 243 Query 245 GCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFY 304 GCTIKLL+ICER E V+ARV+PA++PLSHPLA+V GA+NAV VE++AAG+LMFY Sbjct 244 GCTIKLLAICERA---EDGASVTARVHPAMIPLSHPLASVRGAYNAVFVESDAAGQLMFY 300 Query 305 GQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADK 364 G GAGGAPTASAV GDLV RNR+ G+ GP ES YA LPV+PMG + TRY++S++VADK Sbjct 301 GPGAGGAPTASAVLGDLVAVGRNRIGGTTGPGESAYAALPVSPMGEVVTRYHISLDVADK 360 Query 365 PGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDL 424 PGVL+ VA FA+ VSI VRQ+G E A +VVVTH A+DAAL TV+AL L Sbjct 361 PGVLAQVATVFAEHGVSIDTVRQQGKDGE------ASLVVVTHRASDAALGGTVEALRKL 414 Query 425 DVVQGVSSVIRLEG 438 D V+GV+S++R+EG Sbjct 415 DTVRGVASIMRVEG 428 >gi|317506160|ref|ZP_07963982.1| homoserine dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316255548|gb|EFV14796.1| homoserine dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=445 Score = 481 bits (1237), Expect = 1e-133, Method: Compositional matrix adjust. Identities = 277/437 (64%), Positives = 332/437 (76%), Gaps = 10/437 (2%) Query 6 KPVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRG-----VPIE 60 + +GV +LGLG VGSEV R++ AE+LAARVGA LVLRG+ VR + RG V Sbjct 10 REIGVGLLGLGTVGSEVARVLIEDAEELAARVGAKLVLRGVAVRNLDAARGASAGLVDPA 69 Query 61 LLTDDIEELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQA 120 LLT + ELV R+DVD+VVE++G + P+++ I AL GKSVV+ANKAL A + +L +A Sbjct 70 LLTTEAAELVERDDVDVVVELIGGINPAKELIRQALRAGKSVVSANKALFAAHSAKLFEA 129 Query 121 AESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYAS 180 A+ A VDL+FEAAVAGAIPVIRPL QSLAGD V VAGIVNGTTN+ILSAMDS G DYA Sbjct 130 AQKAKVDLFFEAAVAGAIPVIRPLRQSLAGDRVTTVAGIVNGTTNFILSAMDSEGDDYAD 189 Query 181 ALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGS 240 L A LGYAEADPTADV G+DAAAK AILASIAFHTRVTA DV+ EGIT++T AD S Sbjct 190 VLRQAQELGYAEADPTADVGGHDAAAKTAILASIAFHTRVTASDVHVEGITEITAADVES 249 Query 241 AHALGCTIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR 300 A LG TIKLLS+ ER+ ++G +RVSARVYPALVP SHPLA+VNGA+NAVVVEA AGR Sbjct 250 AKQLGYTIKLLSLSERVVGEDGKERVSARVYPALVPRSHPLASVNGAYNAVVVEAVNAGR 309 Query 301 LMFYGQGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMN 360 LMFYGQGAGGAPTAS+V GDLV AARN VLG ES YA+LP+A +G + RY+V M Sbjct 310 LMFYGQGAGGAPTASSVAGDLVAAARNVVLGRAVASESTYAKLPIASIGDVAARYFVRMR 369 Query 361 VADKPGVLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDA 420 V D+PGVLS+VA+ FAKR+VSIA V Q+GV+ GA I+++TH A +AL+ETV Sbjct 370 VDDRPGVLSSVASVFAKRDVSIATVLQKGVI-----EGGAEIIIITHSALGSALAETVRE 424 Query 421 LDDLDVVQGVSSVIRLE 437 ++DL V V SV+RLE Sbjct 425 VEDLPAVVEVESVLRLE 441 >gi|331695514|ref|YP_004331753.1| homoserine dehydrogenase [Pseudonocardia dioxanivorans CB1190] gi|326950203|gb|AEA23900.1| homoserine dehydrogenase [Pseudonocardia dioxanivorans CB1190] Length=456 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 273/438 (63%), Positives = 339/438 (78%), Gaps = 4/438 (0%) Query 7 PVGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDRGVPIELLTDDI 66 P+ VA+LG G VG E+VR++ + A+DLAARVGAP+ L G+ VRR +P L+T D Sbjct 9 PIRVALLGCGTVGGEIVRLLTDQADDLAARVGAPVELVGVAVRRPHKHPELPAGLVTADA 68 Query 67 EELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHV 126 LV R+DVDIVVEV+G +EP R +L AL+ GKSVVTANKALLA LA+AA+++ Sbjct 69 AGLVTRDDVDIVVEVVGGIEPVRTLLLEALKAGKSVVTANKALLAEDGAVLAEAADASGA 128 Query 127 DLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADAS 186 DLY+EAAVAGAIP++RPL +SL GD + RVAGIVNGTTN+ILS+M S+GA Y AL +A+ Sbjct 129 DLYYEAAVAGAIPLLRPLRESLVGDRITRVAGIVNGTTNFILSSMASSGAGYTDALEEAT 188 Query 187 ALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGC 246 LGYAEADP+ADV+GYDAA+KAAILAS+AFHTRVTA DV+ EGI V+ AD +A +L C Sbjct 189 RLGYAEADPSADVDGYDAASKAAILASLAFHTRVTAADVHCEGIRTVSAADIAAAASLDC 248 Query 247 TIKLLSICERITTDEG-SQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYG 305 TIKLL+ICER+ +++G + VSARVYPA++P +HPLA+V+GAFNAV VEAEAAG+LMFYG Sbjct 249 TIKLLAICERVPSEDGAADAVSARVYPAMIPSAHPLASVDGAFNAVFVEAEAAGQLMFYG 308 Query 306 QGAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKP 365 QGAGGAPTASAV GDLV RN V+G RGPRES YA LPV PMG + TRY+VS+ VAD+ Sbjct 309 QGAGGAPTASAVLGDLVAVGRNLVVGGRGPRESTYASLPVLPMGAVSTRYHVSLEVADRA 368 Query 366 GVLSAVAAEFAKREVSIAEVRQ---EGVVDEGGRRVGARIVVVTHLATDAALSETVDALD 422 GVL+AVA EFA+ +VSIA VRQ G R+VVVTH A D+AL+ TV+AL+ Sbjct 369 GVLAAVAREFAQHDVSIAAVRQYGGGRNGGSAGGSAAVRLVVVTHAAPDSALASTVEALE 428 Query 423 DLDVVQGVSSVIRLEGTG 440 LD V+GV SV+R+E G Sbjct 429 GLDAVRGVESVLRVEDLG 446 >gi|325295761|gb|ADZ04937.1| homoserine dehydrogenase [Corynebacterium pekinense] Length=445 Score = 480 bits (1235), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 261/431 (61%), Positives = 331/431 (77%), Gaps = 7/431 (1%) Query 8 VGVAVLGLGNVGSEVVRIIENSAEDLAARVGAPLVLRGIGVRRVTTDR-GVPIELLTDDI 66 VG+A+LG G VG+EV+R++ ++LA R+G PL +RGI V ++ R GV ELLT+D Sbjct 19 VGIALLGFGTVGTEVMRLMTEYGDELAHRIGGPLEVRGIAVSDISKPREGVAPELLTEDA 78 Query 67 EELVAREDVDIVVEVMGPVEPSRKAILGALERGKSVVTANKALLATSTGELAQAAESAHV 126 L+ REDVDIVVEV+G +E R+ +L AL+ GKSVVTANKAL+A + ELA AAE+A+V Sbjct 79 FALIEREDVDIVVEVIGGIEYPREVVLAALKAGKSVVTANKALVAAHSAELADAAEAANV 138 Query 127 DLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYASALADAS 186 DLYFEAAVAGAIPV+ PL +SLAGD + V GIVNGTTN+IL AMDSTGADYA +LA+A+ Sbjct 139 DLYFEAAVAGAIPVVGPLRRSLAGDQIQSVMGIVNGTTNFILDAMDSTGADYADSLAEAT 198 Query 187 ALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTPADFGSAHALGC 246 LGYAEADPTADVEG+DAA+KAAILASIAFHTRVTADDVY EGI+ ++ AD +A G Sbjct 199 RLGYAEADPTADVEGHDAASKAAILASIAFHTRVTADDVYCEGISNISAADIEAAQQAGH 258 Query 247 TIKLLSICERITTDEGSQRVSARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGRLMFYGQ 306 TIKLL+ICE+ T EG +SARV+P L+P+SHPLA+VN +FNA+ VEAEAAGRL FYG Sbjct 259 TIKLLAICEKFTNKEGKSAISARVHPTLLPVSHPLASVNKSFNAIFVEAEAAGRLTFYGN 318 Query 307 GAGGAPTASAVTGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFIETRYYVSMNVADKPG 366 GAGGAPTASAV GD+V AARN+V G R P ES YA LP+A G TRY++ M+V D+ G Sbjct 319 GAGGAPTASAVLGDVVGAARNKVHGGRAPGESTYANLPIADFGETTTRYHLDMDVEDRVG 378 Query 367 VLSAVAAEFAKREVSIAEVRQEGVVDEGGRRVGARIVVVTHLATDAALSETVDALDDLDV 426 VL+ +A+ F+++ +S+ +RQE D+ AR++VVTH A ++ LS TV+ L V Sbjct 379 VLAELASLFSEQGISLRTIRQEERDDD------ARLIVVTHSALESDLSRTVELLKAKPV 432 Query 427 VQGVSSVIRLE 437 V+ ++SVIRLE Sbjct 433 VKAINSVIRLE 443 Lambda K H 0.316 0.132 0.361 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 906527000372 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40