BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1296 Length=316 Score E Sequences producing significant alignments: (Bits) Value gi|15608436|ref|NP_215812.1| homoserine kinase [Mycobacterium tu... 618 3e-175 gi|289446891|ref|ZP_06436635.1| homoserine kinase thrB [Mycobact... 616 1e-174 gi|289573959|ref|ZP_06454186.1| homoserine kinase thrB [Mycobact... 616 2e-174 gi|289554914|ref|ZP_06444124.1| homoserine kinase thrB [Mycobact... 614 5e-174 gi|15827562|ref|NP_301825.1| homoserine kinase [Mycobacterium le... 468 4e-130 gi|699339|gb|AAA63100.1| thrB [Mycobacterium leprae] 467 8e-130 gi|240169518|ref|ZP_04748177.1| homoserine kinase [Mycobacterium... 466 2e-129 gi|296170237|ref|ZP_06851830.1| homoserine kinase [Mycobacterium... 457 1e-126 gi|41408564|ref|NP_961400.1| homoserine kinase [Mycobacterium av... 450 1e-124 gi|254774335|ref|ZP_05215851.1| homoserine kinase [Mycobacterium... 450 1e-124 gi|336460913|gb|EGO39796.1| homoserine kinase [Mycobacterium avi... 449 3e-124 gi|118462633|ref|YP_880750.1| homoserine kinase [Mycobacterium a... 447 1e-123 gi|183984072|ref|YP_001852363.1| homoserine kinase ThrB [Mycobac... 441 8e-122 gi|118619172|ref|YP_907504.1| homoserine kinase [Mycobacterium u... 434 1e-119 gi|342858043|ref|ZP_08714699.1| homoserine kinase [Mycobacterium... 431 5e-119 gi|254821295|ref|ZP_05226296.1| homoserine kinase [Mycobacterium... 427 1e-117 gi|118470495|ref|YP_889207.1| homoserine kinase [Mycobacterium s... 408 5e-112 gi|126436456|ref|YP_001072147.1| homoserine kinase [Mycobacteriu... 392 3e-107 gi|145222888|ref|YP_001133566.1| homoserine kinase [Mycobacteriu... 378 7e-103 gi|108800858|ref|YP_641055.1| homoserine kinase [Mycobacterium s... 374 1e-101 gi|315443353|ref|YP_004076232.1| homoserine kinase [Mycobacteriu... 367 1e-99 gi|333989935|ref|YP_004522549.1| homoserine kinase ThrB [Mycobac... 365 7e-99 gi|120405300|ref|YP_955129.1| homoserine kinase [Mycobacterium v... 356 2e-96 gi|229490003|ref|ZP_04383856.1| homoserine kinase [Rhodococcus e... 341 1e-91 gi|226307407|ref|YP_002767367.1| homoserine kinase [Rhodococcus ... 341 1e-91 gi|111018487|ref|YP_701459.1| homoserine kinase [Rhodococcus jos... 339 3e-91 gi|325673532|ref|ZP_08153223.1| homoserine kinase [Rhodococcus e... 335 7e-90 gi|312139163|ref|YP_004006499.1| homoserine kinase thrb [Rhodoco... 334 9e-90 gi|226360610|ref|YP_002778388.1| homoserine kinase [Rhodococcus ... 334 1e-89 gi|169628528|ref|YP_001702177.1| homoserine kinase [Mycobacteriu... 321 7e-86 gi|333920932|ref|YP_004494513.1| Homoserine kinase [Amycolicicoc... 307 1e-81 gi|54023018|ref|YP_117260.1| homoserine kinase [Nocardia farcini... 306 4e-81 gi|319948890|ref|ZP_08023002.1| homoserine kinase [Dietzia cinna... 290 3e-76 gi|296138959|ref|YP_003646202.1| homoserine kinase [Tsukamurella... 275 1e-71 gi|336325983|ref|YP_004605949.1| Homoserine kinase [Corynebacter... 270 2e-70 gi|334563586|ref|ZP_08516577.1| homoserine kinase [Corynebacteri... 266 4e-69 gi|237785872|ref|YP_002906577.1| homoserine kinase [Corynebacter... 265 7e-69 gi|326382078|ref|ZP_08203771.1| homoserine kinase [Gordonia neof... 256 4e-66 gi|305681844|ref|ZP_07404648.1| homoserine kinase [Corynebacteri... 255 6e-66 gi|145295323|ref|YP_001138144.1| homoserine kinase [Corynebacter... 255 7e-66 gi|19552408|ref|NP_600410.1| homoserine kinase [Corynebacterium ... 254 9e-66 gi|225022818|ref|ZP_03712010.1| hypothetical protein CORMATOL_02... 254 2e-65 gi|25027846|ref|NP_737900.1| homoserine kinase [Corynebacterium ... 254 2e-65 gi|172040375|ref|YP_001800089.1| homoserine kinase [Corynebacter... 253 4e-65 gi|343928054|ref|ZP_08767519.1| homoserine kinase [Gordonia alka... 252 7e-65 gi|227547997|ref|ZP_03978046.1| homoserine kinase [Corynebacteri... 249 3e-64 gi|337290506|ref|YP_004629527.1| Homoserine kinase [Corynebacter... 249 5e-64 gi|38233632|ref|NP_939399.1| homoserine kinase [Corynebacterium ... 248 7e-64 gi|213964485|ref|ZP_03392685.1| homoserine kinase [Corynebacteri... 246 4e-63 gi|300781426|ref|ZP_07091280.1| homoserine kinase [Corynebacteri... 243 3e-62 >gi|15608436|ref|NP_215812.1| homoserine kinase [Mycobacterium tuberculosis H37Rv] gi|15840746|ref|NP_335783.1| homoserine kinase [Mycobacterium tuberculosis CDC1551] gi|31792489|ref|NP_854982.1| homoserine kinase [Mycobacterium bovis AF2122/97] 72 more sequence titles Length=316 Score = 618 bits (1594), Expect = 3e-175, Method: Compositional matrix adjust. Identities = 316/316 (100%), Positives = 316/316 (100%), Gaps = 0/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD Sbjct 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV Sbjct 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI Sbjct 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ Sbjct 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL Sbjct 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 Query 301 TVGEAVRWSPTVRVPG 316 TVGEAVRWSPTVRVPG Sbjct 301 TVGEAVRWSPTVRVPG 316 >gi|289446891|ref|ZP_06436635.1| homoserine kinase thrB [Mycobacterium tuberculosis CPHL_A] gi|289419849|gb|EFD17050.1| homoserine kinase thrB [Mycobacterium tuberculosis CPHL_A] Length=316 Score = 616 bits (1589), Expect = 1e-174, Method: Compositional matrix adjust. Identities = 315/316 (99%), Positives = 316/316 (100%), Gaps = 0/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD Sbjct 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRAV+HGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV Sbjct 61 QVPLGPEHLVVRAVRHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI Sbjct 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ Sbjct 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL Sbjct 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 Query 301 TVGEAVRWSPTVRVPG 316 TVGEAVRWSPTVRVPG Sbjct 301 TVGEAVRWSPTVRVPG 316 >gi|289573959|ref|ZP_06454186.1| homoserine kinase thrB [Mycobacterium tuberculosis K85] gi|339631365|ref|YP_004723007.1| homoserine kinase [Mycobacterium africanum GM041182] gi|289538390|gb|EFD42968.1| homoserine kinase thrB [Mycobacterium tuberculosis K85] gi|339330721|emb|CCC26390.1| putative homoserine kinase THRB [Mycobacterium africanum GM041182] Length=316 Score = 616 bits (1588), Expect = 2e-174, Method: Compositional matrix adjust. Identities = 315/316 (99%), Positives = 315/316 (99%), Gaps = 0/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD Sbjct 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV Sbjct 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI Sbjct 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ Sbjct 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 QRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL Sbjct 241 SQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 Query 301 TVGEAVRWSPTVRVPG 316 TVGEAVRWSPTVRVPG Sbjct 301 TVGEAVRWSPTVRVPG 316 >gi|289554914|ref|ZP_06444124.1| homoserine kinase thrB [Mycobacterium tuberculosis KZN 605] gi|308371933|ref|ZP_07667272.1| homoserine kinase thrB [Mycobacterium tuberculosis SUMu004] gi|289439546|gb|EFD22039.1| homoserine kinase thrB [Mycobacterium tuberculosis KZN 605] gi|308335069|gb|EFP23920.1| homoserine kinase thrB [Mycobacterium tuberculosis SUMu004] Length=315 Score = 614 bits (1584), Expect = 5e-174, Method: Compositional matrix adjust. Identities = 314/315 (99%), Positives = 315/315 (100%), Gaps = 0/315 (0%) Query 2 VTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQ 61 +TQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQ Sbjct 1 MTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQ 60 Query 62 VPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVV 121 VPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVV Sbjct 61 VPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVV 120 Query 122 QTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIR 181 QTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIR Sbjct 121 QTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIR 180 Query 182 LFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQP 241 LFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQP Sbjct 181 LFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQP 240 Query 242 QRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELT 301 QRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELT Sbjct 241 QRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELT 300 Query 302 VGEAVRWSPTVRVPG 316 VGEAVRWSPTVRVPG Sbjct 301 VGEAVRWSPTVRVPG 315 >gi|15827562|ref|NP_301825.1| homoserine kinase [Mycobacterium leprae TN] gi|221230039|ref|YP_002503455.1| homoserine kinase [Mycobacterium leprae Br4923] gi|13432180|sp|P45836.2|KHSE_MYCLE RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|254807819|sp|B8ZR28.1|KHSE_MYCLB RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|13093112|emb|CAC31512.1| homoserine kinase [Mycobacterium leprae] gi|219933146|emb|CAR71226.1| homoserine kinase [Mycobacterium leprae Br4923] Length=315 Score = 468 bits (1205), Expect = 4e-130, Method: Compositional matrix adjust. Identities = 258/316 (82%), Positives = 281/316 (89%), Gaps = 1/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVT +LP+GLVASAVVAASSANLGPGFDS+GLALSL DEI+VETTDSGL V VDGEG D Sbjct 1 MVTW-MLPAGLVASAVVAASSANLGPGFDSIGLALSLCDEIVVETTDSGLVVVVDGEGAD 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVP+GPEHLVVRAV+ GLQA GVSAAGL VRCRNAIPHSRGLGSSAAAVVGGLA VNG V Sbjct 60 QVPMGPEHLVVRAVRRGLQAVGVSAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAVVNGFV 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Q DS+P S+A+LIQLASEFEGHPDNAAAAVLGGAVVSW D S D+P+Y AV LRLHPDI Sbjct 120 AQIDSTPLSNAQLIQLASEFEGHPDNAAAAVLGGAVVSWVDRSYDQPDYCAVPLRLHPDI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 LF AIPE+RSSTAE+RVLLPA+VSHDDARFNVSRAALLVVALTERPDLLMAATED+LHQ Sbjct 180 HLFAAIPEERSSTAESRVLLPARVSHDDARFNVSRAALLVVALTERPDLLMAATEDVLHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 P RA+AM+ASAEYLRLLRRHNVAA LSGAGPSLIALST SELP +A E+GAA GF + ++ Sbjct 240 PHRASAMSASAEYLRLLRRHNVAATLSGAGPSLIALSTQSELPREAAEYGAANGFIIIKM 299 Query 301 TVGEAVRWSPTVRVPG 316 T G+ V W P V VPG Sbjct 300 TAGDEVCWRPEVTVPG 315 >gi|699339|gb|AAA63100.1| thrB [Mycobacterium leprae] Length=314 Score = 467 bits (1202), Expect = 8e-130, Method: Compositional matrix adjust. Identities = 255/311 (82%), Positives = 278/311 (90%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GLVASAVVAASSANLGPGFDS+GLALSL DEI+VETTDSGL V VDGEG DQVP+G Sbjct 4 MLPAGLVASAVVAASSANLGPGFDSIGLALSLCDEIVVETTDSGLVVVVDGEGADQVPMG 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 PEHLVVRAV+ GLQA GVSAAGL VRCRNAIPHSRGLGSSAAAVVGGLA VNG V Q DS Sbjct 64 PEHLVVRAVRRGLQAVGVSAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAVVNGFVAQIDS 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 +P S+A+LIQLASEFEGHPDNAAAAVLGGAVVSW D S D+P+Y AV LRLHPDI LF A Sbjct 124 TPLSNAQLIQLASEFEGHPDNAAAAVLGGAVVSWVDRSYDQPDYCAVPLRLHPDIHLFAA 183 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IPE+RSSTAE+RVLLPA+VSHDDARFNVSRAALLVVALTERPDLLMAATED+LHQP RA+ Sbjct 184 IPEERSSTAESRVLLPARVSHDDARFNVSRAALLVVALTERPDLLMAATEDVLHQPHRAS 243 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM+ASAEYLRLLRRHNVAA LSGAGPSLIALST SELP +A E+GAA GF + ++T G+ Sbjct 244 AMSASAEYLRLLRRHNVAATLSGAGPSLIALSTQSELPREAAEYGAANGFIIIKMTAGDE 303 Query 306 VRWSPTVRVPG 316 V W P V VPG Sbjct 304 VCWRPEVTVPG 314 >gi|240169518|ref|ZP_04748177.1| homoserine kinase [Mycobacterium kansasii ATCC 12478] Length=315 Score = 466 bits (1200), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 254/316 (81%), Positives = 283/316 (90%), Gaps = 1/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVTQ+L P+GLVASAVVAASSANLGPGFDS+GLALSLYDEI VETTDSGLTV V+GEG D Sbjct 1 MVTQSL-PAGLVASAVVAASSANLGPGFDSIGLALSLYDEIEVETTDSGLTVLVEGEGAD 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRA++HGL+A G A GL VRCRNAIPHSRGLGSSAAAVVGGLA VNGLV Sbjct 60 QVPLGPEHLVVRAIRHGLRAVGAQAGGLVVRCRNAIPHSRGLGSSAAAVVGGLAVVNGLV 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 VQ DS P SDA+LIQL+SEFEGHPDNAAAAVLGGAVVSW D +GD PNYSAV L LHPDI Sbjct 120 VQVDSKPLSDAQLIQLSSEFEGHPDNAAAAVLGGAVVSWIDRTGDCPNYSAVPLHLHPDI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 LF+AIPE+RSSTAETRVLLPAQVSHD+ARFN+SR ALLVVALT+RPDLLM ATED+LHQ Sbjct 180 HLFSAIPEERSSTAETRVLLPAQVSHDEARFNISRVALLVVALTQRPDLLMPATEDVLHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 PQRA AM ASAEYLRLLRRHNVAA +SGAGP+LI ++T+ ELP++AVE+GAA GF+VT + Sbjct 240 PQRAPAMPASAEYLRLLRRHNVAATISGAGPALITMTTEPELPSEAVEYGAAHGFSVTAM 299 Query 301 TVGEAVRWSPTVRVPG 316 T G+ VRW+P V + G Sbjct 300 TAGDRVRWNPGVAIIG 315 >gi|296170237|ref|ZP_06851830.1| homoserine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895113|gb|EFG74831.1| homoserine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=314 Score = 457 bits (1176), Expect = 1e-126, Method: Compositional matrix adjust. Identities = 249/311 (81%), Positives = 274/311 (89%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 LLP+GL ASAVV+ASSANLGPGFDS+GLAL L DEI+V+T DSGL V V+GEG +QVP G Sbjct 4 LLPAGLEASAVVSASSANLGPGFDSIGLALRLSDEIVVQTADSGLVVLVEGEGAEQVPRG 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 PEHLVVRAV+ GL+A GV A GL VRCRNAIPHSRGLGSSAAA VGGLAA NGLV QTDS Sbjct 64 PEHLVVRAVECGLRAMGVRAGGLVVRCRNAIPHSRGLGSSAAAAVGGLAAANGLVAQTDS 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P S+A+LIQL+SEFEGHPDNA+AAVLGGAVVSW D SGDRP YSA S+RLHPDIRL+ A Sbjct 124 RPLSEAQLIQLSSEFEGHPDNASAAVLGGAVVSWIDRSGDRPRYSAASVRLHPDIRLYCA 183 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IP++RS TAETRVLLP QVSHDDARFNVSRAALLVVAL+ERPDLLM ATED+LHQPQRA Sbjct 184 IPQERSLTAETRVLLPTQVSHDDARFNVSRAALLVVALSERPDLLMPATEDVLHQPQRAP 243 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYLRLLRRHNVAA LSGAGP+LIALST+ ELP + VE+GAA GFA+TE+T GE Sbjct 244 AMPASAEYLRLLRRHNVAATLSGAGPALIALSTEPELPAEVVEYGAANGFALTEMTAGEG 303 Query 306 VRWSPTVRVPG 316 VRWSP V VPG Sbjct 304 VRWSPGVTVPG 314 >gi|41408564|ref|NP_961400.1| homoserine kinase [Mycobacterium avium subsp. paratuberculosis K-10] gi|59798350|sp|Q73X44.1|KHSE_MYCPA RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|41396922|gb|AAS04783.1| ThrB [Mycobacterium avium subsp. paratuberculosis K-10] Length=315 Score = 450 bits (1158), Expect = 1e-124, Method: Compositional matrix adjust. Identities = 249/316 (79%), Positives = 272/316 (87%), Gaps = 1/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVT ++LP+GLVASAVV+ASSANLGPGFDS+GLALSL DEI VETTDSGL V V+GEG D Sbjct 1 MVT-SMLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGAD 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRAV+ GL+A GV AAGL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV Sbjct 60 QVPLGPEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLV 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Q + P SDA LIQL+SEFEGHPDNAAAAV GGA+VSW D G P Y+A LRLHPDI Sbjct 120 AQANCQPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 L+ AIP++RS TAETRVLLPAQVSH+DARFNVSRAALLVVALTERPDLLMAATED+LHQ Sbjct 180 HLYCAIPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 PQRA AM ASAEYLRLLRRHNVAA LSGAGPSLIAL+T S LP + +E+GAA GF + E+ Sbjct 240 PQRAPAMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVMEYGAANGFTLAEM 299 Query 301 TVGEAVRWSPTVRVPG 316 T GE VRWSP V V G Sbjct 300 TAGEGVRWSPGVTVVG 315 >gi|254774335|ref|ZP_05215851.1| homoserine kinase [Mycobacterium avium subsp. avium ATCC 25291] Length=315 Score = 450 bits (1158), Expect = 1e-124, Method: Compositional matrix adjust. Identities = 249/316 (79%), Positives = 271/316 (86%), Gaps = 1/316 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVT ++LP+GLVASAVV+ASSANLGPGFDS+GLALSL DEI VETTDSGL V V+GEG D Sbjct 1 MVT-SMLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGAD 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPLGPEHLVVRAV+ GL+A GV AAGL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV Sbjct 60 QVPLGPEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLV 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 Q + P SDA LIQL+SEFEGHPDNAAAAV GGA+VSW D G P Y+A LRLHPDI Sbjct 120 AQANCQPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 L+ AIP++RS TAETRVLLPAQVSH+DARFNVSRAALLVVALTERPDLLMAATED+LHQ Sbjct 180 HLYCAIPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 PQRA AM ASAEYLRLLRRHNVAA LSGAGPSLIAL+T S LP + E+GAA GF + E+ Sbjct 240 PQRAPAMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVTEYGAANGFTLAEM 299 Query 301 TVGEAVRWSPTVRVPG 316 T GE VRWSP V V G Sbjct 300 TAGEGVRWSPGVTVVG 315 >gi|336460913|gb|EGO39796.1| homoserine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=311 Score = 449 bits (1154), Expect = 3e-124, Method: Compositional matrix adjust. Identities = 246/311 (80%), Positives = 268/311 (87%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GLVASAVV+ASSANLGPGFDS+GLALSL DEI VETTDSGL V V+GEG DQVPLG Sbjct 1 MLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGADQVPLG 60 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 PEHLVVRAV+ GL+A GV AAGL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV Q + Sbjct 61 PEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQANC 120 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P SDA LIQL+SEFEGHPDNAAAAV GGA+VSW D G P Y+A LRLHPDI L+ A Sbjct 121 QPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDIHLYCA 180 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IP++RS TAETRVLLPAQVSH+DARFNVSRAALLVVALTERPDLLMAATED+LHQPQRA Sbjct 181 IPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQPQRAP 240 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYLRLLRRHNVAA LSGAGPSLIAL+T S LP + +E+GAA GF + E+T GE Sbjct 241 AMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVMEYGAANGFTLAEMTAGEG 300 Query 306 VRWSPTVRVPG 316 VRWSP V V G Sbjct 301 VRWSPGVTVVG 311 >gi|118462633|ref|YP_880750.1| homoserine kinase [Mycobacterium avium 104] gi|118163920|gb|ABK64817.1| homoserine kinase [Mycobacterium avium 104] Length=311 Score = 447 bits (1150), Expect = 1e-123, Method: Compositional matrix adjust. Identities = 245/311 (79%), Positives = 267/311 (86%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GLVASAVV+ASSANLGPGFDS+GLALSL DEI VETTDSGL V V+GEG DQVPLG Sbjct 1 MLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGADQVPLG 60 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 PEHLVVRAV+ GL+A GV AAGL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV Q + Sbjct 61 PEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQANC 120 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P SDA LIQL+SEFEGHPDNAAAAV GGA+VSW D G P Y+A LRLHPDI L+ A Sbjct 121 QPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDIHLYCA 180 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IP++RS TAETRVLLPAQVSH+DARFNVSRAALLVVALTERPDLLMAATED+LHQPQRA Sbjct 181 IPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQPQRAP 240 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYLRLLRRHNVAA LSGAGPSLIAL+T S LP + E+GAA GF + E+T G+ Sbjct 241 AMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVTEYGAANGFTLAEMTAGQG 300 Query 306 VRWSPTVRVPG 316 VRWSP V V G Sbjct 301 VRWSPGVTVVG 311 >gi|183984072|ref|YP_001852363.1| homoserine kinase ThrB [Mycobacterium marinum M] gi|183177398|gb|ACC42508.1| homoserine kinase ThrB [Mycobacterium marinum M] Length=314 Score = 441 bits (1134), Expect = 8e-122, Method: Compositional matrix adjust. Identities = 244/307 (80%), Positives = 270/307 (88%), Gaps = 0/307 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LPSGLVASAVVAASSANLGPGFDS+GLALSLYDEI++ETTDSGL V V+GEG QVPL Sbjct 4 VLPSGLVASAVVAASSANLGPGFDSLGLALSLYDEIVLETTDSGLEVVVEGEGSGQVPLN 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 EHLVVRA+QHGL+A GVSAAGL VRCRN IPHSRGLGSSA+AVVGGLAAVNGLV Q Sbjct 64 SEHLVVRAIQHGLRAVGVSAAGLIVRCRNDIPHSRGLGSSASAVVGGLAAVNGLVSQAGW 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 +P SD +LIQL+SEFEGHPDNAAAAVLGGAVVSW + GDR +YSAV L LHPDI LF+A Sbjct 124 APLSDQQLIQLSSEFEGHPDNAAAAVLGGAVVSWIERCGDRADYSAVQLDLHPDIHLFSA 183 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IPE RSSTAETRVLLP VSHDDARFN+SRAALLVVALT+RPDLLMAATED+LHQPQRA+ Sbjct 184 IPEVRSSTAETRVLLPDLVSHDDARFNISRAALLVVALTQRPDLLMAATEDVLHQPQRAS 243 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYL+LLRRH VAA LSGAGP+LIALSTD +LP +AVE+GAA GF +T +T G+ Sbjct 244 AMPASAEYLQLLRRHKVAATLSGAGPALIALSTDPDLPPEAVEYGAANGFTITAMTAGDR 303 Query 306 VRWSPTV 312 VRW P V Sbjct 304 VRWKPGV 310 >gi|118619172|ref|YP_907504.1| homoserine kinase [Mycobacterium ulcerans Agy99] gi|166220517|sp|A0PUL4.1|KHSE_MYCUA RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|118571282|gb|ABL06033.1| homoserine kinase ThrB [Mycobacterium ulcerans Agy99] Length=314 Score = 434 bits (1115), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 240/307 (79%), Positives = 267/307 (87%), Gaps = 0/307 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LPSGLVASAVVAASSANLGPGFDS+GLALSLYDEI++ETTDSGL V V+GEG QVPL Sbjct 4 VLPSGLVASAVVAASSANLGPGFDSLGLALSLYDEIVLETTDSGLEVVVEGEGAGQVPLN 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 EHLVVRA+QHGL+A GV A GL VRCRN IPHSRGLGSSA+AVVGGLAAVNGLV Q Sbjct 64 SEHLVVRAIQHGLRAVGVPATGLIVRCRNDIPHSRGLGSSASAVVGGLAAVNGLVSQAGW 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P SD +LIQL+SEFEGHPDNAAAAVLGGAVVSW + GDR +YSAV L LHPDI LF+A Sbjct 124 VPLSDQQLIQLSSEFEGHPDNAAAAVLGGAVVSWIERCGDRADYSAVQLDLHPDIHLFSA 183 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IPE RSSTAETRVLLP VSHDDARFN+SRAALLVVALT+RPDLLMAATED+LHQPQRA+ Sbjct 184 IPEVRSSTAETRVLLPDLVSHDDARFNISRAALLVVALTQRPDLLMAATEDVLHQPQRAS 243 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYL+LLRRH VAA LSGAGP+LIAL+T+ +LP +AVE+GAA GF +T +T G+ Sbjct 244 AMPASAEYLQLLRRHKVAATLSGAGPALIALTTNPDLPPEAVEYGAANGFTITAMTAGDR 303 Query 306 VRWSPTV 312 VRW P V Sbjct 304 VRWKPGV 310 >gi|342858043|ref|ZP_08714699.1| homoserine kinase [Mycobacterium colombiense CECT 3035] gi|342135376|gb|EGT88542.1| homoserine kinase [Mycobacterium colombiense CECT 3035] Length=311 Score = 431 bits (1109), Expect = 5e-119, Method: Compositional matrix adjust. Identities = 247/311 (80%), Positives = 274/311 (89%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GLVASAVV+ASSANLGPGFDS+GLALSLYDEIIVETTDSGL V V+GEG Q+P+G Sbjct 1 MLPAGLVASAVVSASSANLGPGFDSIGLALSLYDEIIVETTDSGLVVLVEGEGAGQLPVG 60 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 PEHLVVRA++ GL+A GV A GL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV QTD Sbjct 61 PEHLVVRALECGLRAVGVRAPGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQTDW 120 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P S A+LIQL+SEFEGHPDNAAAAVLGGAVVSW +GDRP Y+AV LRLHPDI L++A Sbjct 121 QPLSPAQLIQLSSEFEGHPDNAAAAVLGGAVVSWVGRTGDRPQYAAVPLRLHPDIHLYSA 180 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IPE+RS TAETRVLLPAQVSH+DARFNVSRAALLVVALTERPDLLMAATED+LHQPQRA Sbjct 181 IPEERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQPQRAP 240 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYLRLLRRHN+AA LSGAGPSLIAL+T +ELP + E+G A GFA+TE+ GE Sbjct 241 AMPASAEYLRLLRRHNLAATLSGAGPSLIALTTAAELPGEVAEYGEANGFAITEMAAGEP 300 Query 306 VRWSPTVRVPG 316 VRW+P V V G Sbjct 301 VRWNPGVTVAG 311 >gi|254821295|ref|ZP_05226296.1| homoserine kinase [Mycobacterium intracellulare ATCC 13950] Length=311 Score = 427 bits (1097), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 237/311 (77%), Positives = 265/311 (86%), Gaps = 0/311 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GLVA+AVV+ASSANLGPGFDS+GLALSL DEI VETT SGL VTV+GEG Q+P+ Sbjct 1 MLPAGLVATAVVSASSANLGPGFDSIGLALSLCDEITVETTSSGLVVTVEGEGAGQLPVD 60 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 +HLVVRA++ GLQA GV A GL VRCRNAIPHSRGLGSSAAAVVGGLAA NGLV QTD Sbjct 61 ADHLVVRALERGLQAVGVRAPGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQTDW 120 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 D +LIQL+S+FEGHPDNAAAAVLGGAVVSW D SGD P Y+AV LRLHPDI L+ A Sbjct 121 QTLDDTQLIQLSSDFEGHPDNAAAAVLGGAVVSWVDRSGDHPRYAAVPLRLHPDIHLYCA 180 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 +PE+RS TAETRVLLPAQVSHDDARFNVSR ALLVVALTERPDLLMAATED+LHQPQRA Sbjct 181 VPEERSLTAETRVLLPAQVSHDDARFNVSRTALLVVALTERPDLLMAATEDVLHQPQRAP 240 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASAEYLRLLRRHNVAA LSGAGPS+IA++T + LP +AVE+ A GFA+ ++ GE Sbjct 241 AMPASAEYLRLLRRHNVAATLSGAGPSVIAMTTAAGLPPEAVEYAATSGFALIKMAAGER 300 Query 306 VRWSPTVRVPG 316 VRWSP V V G Sbjct 301 VRWSPGVTVAG 311 >gi|118470495|ref|YP_889207.1| homoserine kinase [Mycobacterium smegmatis str. MC2 155] gi|166220514|sp|A0R219.1|KHSE_MYCS2 RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|118171782|gb|ABK72678.1| homoserine kinase [Mycobacterium smegmatis str. MC2 155] Length=317 Score = 408 bits (1049), Expect = 5e-112, Method: Compositional matrix adjust. Identities = 231/306 (76%), Positives = 258/306 (85%), Gaps = 3/306 (0%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP GL A++VVAASSANLGPGFDS+G+ALSLYDEI+VET +SGLTV V+GEG QVPL Sbjct 5 LPVGLSATSVVAASSANLGPGFDSLGIALSLYDEIVVETVESGLTVHVEGEGAGQVPLDQ 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA+ GLQAAG SA GL VRCRN IPHSRGLGSSAAAVVGGLAAVNGLV Q S Sbjct 65 THLVVRAINKGLQAAGFSAPGLVVRCRNDIPHSRGLGSSAAAVVGGLAAVNGLVTQAGSE 124 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHS---GDRPNYSAVSLRLHPDIRLF 183 P DA LIQL+SEFEGHPDNAAAAVLGGAVVSWT+ + G P YSAV +RLHPDIRLF Sbjct 125 PMDDARLIQLSSEFEGHPDNAAAAVLGGAVVSWTEQAGAFGGEPRYSAVPVRLHPDIRLF 184 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 A+P+QRSSTAETRVLLP QVSH DARFN+SRAALLVVAL+ERPDLLMAATED+LHQPQR Sbjct 185 PAVPQQRSSTAETRVLLPEQVSHVDARFNLSRAALLVVALSERPDLLMAATEDVLHQPQR 244 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVG 303 AAAM ASAEYL +LRR +AA LSGAGPS++ LS S LP +A+E+G A GF VTE++VG Sbjct 245 AAAMPASAEYLAILRRCGIAAVLSGAGPSVLGLSAQSGLPAEALEYGTAHGFTVTEMSVG 304 Query 304 EAVRWS 309 VRW+ Sbjct 305 AGVRWT 310 >gi|126436456|ref|YP_001072147.1| homoserine kinase [Mycobacterium sp. JLS] gi|166220515|sp|A3Q3C9.1|KHSE_MYCSJ RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|126236256|gb|ABN99656.1| homoserine kinase [Mycobacterium sp. JLS] Length=314 Score = 392 bits (1008), Expect = 3e-107, Method: Compositional matrix adjust. Identities = 227/303 (75%), Positives = 257/303 (85%), Gaps = 0/303 (0%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL A+A+VAASSANLGPGFDS+GLALSLYDEI+VET DSGLTVTV+GEG QV L Sbjct 5 LPAGLTATAMVAASSANLGPGFDSLGLALSLYDEIVVETVDSGLTVTVEGEGAGQVALDS 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+A G A GL VRCRN IPHSRGLGSSAAAVVGGLAA NGLV QTD + Sbjct 65 SHLVVRAIEAGLRATGCVAPGLVVRCRNDIPHSRGLGSSAAAVVGGLAAANGLVSQTDWT 124 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTAI 186 P + +LIQL+S FEGHPDNAAAAVLGGAVV+WTD +G + Y+A LR+HPDI LF AI Sbjct 125 PLTVEQLIQLSSAFEGHPDNAAAAVLGGAVVTWTDGAGAQARYAAAPLRVHPDIHLFPAI 184 Query 187 PEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAA 246 P+QRSSTAETRVLLP VSH DARFN+SRAALLVVALTERPDLLMAATED+LHQPQRAAA Sbjct 185 PQQRSSTAETRVLLPDTVSHTDARFNLSRAALLVVALTERPDLLMAATEDVLHQPQRAAA 244 Query 247 MTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAV 306 M ASAE+LR+LR VAA LSGAGP++IALST+ ELP +AVEFG A GF + E+ VG+ V Sbjct 245 MPASAEFLRVLRGCGVAAVLSGAGPAVIALSTEPELPAEAVEFGIANGFTIAEMAVGDGV 304 Query 307 RWS 309 RWS Sbjct 305 RWS 307 >gi|145222888|ref|YP_001133566.1| homoserine kinase [Mycobacterium gilvum PYR-GCK] gi|145215374|gb|ABP44778.1| homoserine kinase [Mycobacterium gilvum PYR-GCK] Length=315 Score = 378 bits (971), Expect = 7e-103, Method: Compositional matrix adjust. Identities = 217/312 (70%), Positives = 249/312 (80%), Gaps = 1/312 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVT+ L P G+ A+A VAASSANLGPGFDS+GLA+ LYDEI VETT+SGL V V+GEG Sbjct 1 MVTRTL-PPGVSATAEVAASSANLGPGFDSLGLAVGLYDEISVETTESGLVVEVEGEGAG 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPL HLVVRA+Q GL+ G+ A GL VRCRN IPHSRGLGSSAAAVVGGLAA +GL Sbjct 60 QVPLDESHLVVRAIQRGLRENGIDAPGLIVRCRNRIPHSRGLGSSAAAVVGGLAAASGLA 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 +Q DS+P S L+Q++SEFEGHPDNAAAAVLGGAVVSWT+ GD P Y+AV +RLHP I Sbjct 120 MQADSTPMSAERLVQVSSEFEGHPDNAAAAVLGGAVVSWTEDRGDGPRYAAVQIRLHPAI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 +F AIP+ RSSTAETRVLLP VSH DA FNVSRAALL+VALTERPDLL+AATED LHQ Sbjct 180 TVFAAIPQVRSSTAETRVLLPEHVSHADASFNVSRAALLIVALTERPDLLLAATEDALHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 QRA AM ASAEYL +LRR VA LSGAGPS++ALST++ELP +A EFG GF + + Sbjct 240 SQRAPAMPASAEYLAVLRRCGVAGVLSGAGPSVLALSTEAELPVEAAEFGNRNGFEIVRM 299 Query 301 TVGEAVRWSPTV 312 +VG V WS V Sbjct 300 SVGHGVTWSSGV 311 >gi|108800858|ref|YP_641055.1| homoserine kinase [Mycobacterium sp. MCS] gi|119869998|ref|YP_939950.1| homoserine kinase [Mycobacterium sp. KMS] gi|123178309|sp|Q1B535.1|KHSE_MYCSS RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|166220516|sp|A1UK02.1|KHSE_MYCSK RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|108771277|gb|ABG09999.1| homoserine kinase [Mycobacterium sp. MCS] gi|119696087|gb|ABL93160.1| homoserine kinase [Mycobacterium sp. KMS] Length=314 Score = 374 bits (959), Expect = 1e-101, Method: Compositional matrix adjust. Identities = 226/303 (75%), Positives = 255/303 (85%), Gaps = 0/303 (0%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL A+A VAASSANLGPGFDS+GLALSLYDEI+VET DSGLTVTV+GEG QV L Sbjct 5 LPAGLTATATVAASSANLGPGFDSLGLALSLYDEIVVETVDSGLTVTVEGEGAGQVALDS 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+A G A GL VRCRN IPHSRGLGSSAAAVVGGLAA NGLV QTD + Sbjct 65 SHLVVRAIEAGLRATGCIAPGLVVRCRNDIPHSRGLGSSAAAVVGGLAAANGLVSQTDWT 124 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTAI 186 P + +LIQL+S FEGHPDNAAAAVLGGAVV+WTD +G + Y+A LR+HPDI LF AI Sbjct 125 PLTVEQLIQLSSAFEGHPDNAAAAVLGGAVVTWTDGAGAQARYAAAPLRVHPDIHLFPAI 184 Query 187 PEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAA 246 P+QRSSTAETRVLLP VSH DARFN+SRAALLVVALTERPDLLMAATED+LHQPQRAAA Sbjct 185 PQQRSSTAETRVLLPDTVSHTDARFNLSRAALLVVALTERPDLLMAATEDVLHQPQRAAA 244 Query 247 MTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAV 306 M ASAE+LR+LR VAA LSGAGP++IALST+ LP +AVEFG A GF + E+ VG+ V Sbjct 245 MPASAEFLRVLRGCGVAAVLSGAGPAVIALSTEPVLPAEAVEFGIANGFTIAEMAVGDGV 304 Query 307 RWS 309 RWS Sbjct 305 RWS 307 >gi|315443353|ref|YP_004076232.1| homoserine kinase [Mycobacterium sp. Spyr1] gi|315261656|gb|ADT98397.1| homoserine kinase [Mycobacterium sp. Spyr1] Length=315 Score = 367 bits (943), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 217/312 (70%), Positives = 250/312 (81%), Gaps = 1/312 (0%) Query 1 MVTQALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGD 60 MVT+ L P G+ A+A VAASSANLGPGFDS+GLA+ LYDEI VETT+SGL V V+GEG Sbjct 1 MVTRTL-PPGVSATAEVAASSANLGPGFDSLGLAVGLYDEISVETTESGLVVEVEGEGVG 59 Query 61 QVPLGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLV 120 QVPL HLVVRA+Q GL+ G+ GL VRCRN IPHSRGLGSSAAAVVGGLAA NGL Sbjct 60 QVPLDESHLVVRAIQRGLRENGIDTPGLIVRCRNRIPHSRGLGSSAAAVVGGLAAANGLA 119 Query 121 VQTDSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDI 180 +Q DS+P S L+Q++SEFEGHPDNAAAAVLGGAVVSWT++ GD P Y+AV +RLHP I Sbjct 120 MQADSTPMSAERLVQVSSEFEGHPDNAAAAVLGGAVVSWTENRGDGPRYAAVQIRLHPAI 179 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 +F AIP+ RSSTAETRVLLP VSH DA FNVSRAALL+VALTERPDLL+AATED LHQ Sbjct 180 TVFAAIPQVRSSTAETRVLLPEHVSHADASFNVSRAALLIVALTERPDLLLAATEDALHQ 239 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 QRA AM ASAEYL +LRR VA LSGAGPS++ALST++ELP +A EFG+ GF + + Sbjct 240 SQRAPAMPASAEYLAVLRRCGVAGVLSGAGPSVLALSTEAELPVEAAEFGSRNGFEIVRM 299 Query 301 TVGEAVRWSPTV 312 +VG V WS V Sbjct 300 SVGHGVTWSSGV 311 >gi|333989935|ref|YP_004522549.1| homoserine kinase ThrB [Mycobacterium sp. JDM601] gi|333485903|gb|AEF35295.1| homoserine kinase ThrB [Mycobacterium sp. JDM601] Length=316 Score = 365 bits (936), Expect = 7e-99, Method: Compositional matrix adjust. Identities = 221/313 (71%), Positives = 251/313 (81%), Gaps = 2/313 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 LLP+GL AS VAASSANLGPGFDS+GLAL LYDEIIVET DSGL V V+GEG QVPL Sbjct 4 LLPTGLTASVAVAASSANLGPGFDSLGLALGLYDEIIVETIDSGLVVHVEGEGAGQVPLT 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 +HLVV++++ GLQ G G+ VRCRNAIPH RGLGSSAAAVVGGLAAVNGLV Q D Sbjct 64 ADHLVVQSIRRGLQEVGADVPGMVVRCRNAIPHQRGLGSSAAAVVGGLAAVNGLVAQLDQ 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPN--YSAVSLRLHPDIRLF 183 S++ L+QLASEFEGHPDNAAAAVLGGAVV+WT + D YSAV LRLHPDI LF Sbjct 124 PGLSESRLVQLASEFEGHPDNAAAAVLGGAVVAWTANRADGRGTAYSAVPLRLHPDIHLF 183 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 AIP+ RSSTAETR+LLP QVSH DARFNVSR ALLVVALTERPDLL+ ATEDLLHQPQR Sbjct 184 PAIPQLRSSTAETRMLLPEQVSHRDARFNVSRTALLVVALTERPDLLLEATEDLLHQPQR 243 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVG 303 AAA SA+YL+LLR+ +A LSGAGP++IALST ELP + +E AA+GF VT+L VG Sbjct 244 AAAQPESAQYLQLLRQRGIAGVLSGAGPAVIALSTAPELPAEVLEAPAARGFTVTQLRVG 303 Query 304 EAVRWSPTVRVPG 316 +AV+W+ V V G Sbjct 304 DAVKWNSGVVVRG 316 >gi|120405300|ref|YP_955129.1| homoserine kinase [Mycobacterium vanbaalenii PYR-1] gi|166220518|sp|A1TD73.1|KHSE_MYCVP RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|119958118|gb|ABM15123.1| homoserine kinase [Mycobacterium vanbaalenii PYR-1] Length=314 Score = 356 bits (914), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 216/308 (71%), Positives = 249/308 (81%), Gaps = 0/308 (0%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP GL A+AVVAASSANLGPGFDS+GLA+ LYDEI+VETT+SGL V V+GEG QVPL Sbjct 5 LPPGLTATAVVAASSANLGPGFDSMGLAIGLYDEIVVETTESGLVVEVEGEGSGQVPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+ GVSA GL VRCRN IPHSRGLGSSAAAVVGGLAA NGL QTDS+ Sbjct 65 SHLVVRAIERGLRETGVSAPGLIVRCRNDIPHSRGLGSSAAAVVGGLAAANGLAAQTDST 124 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTAI 186 S L+Q++SEFEGHPDNAAAAVLGGAVV+WT P Y+A +RLHPDI +F A+ Sbjct 125 LMSPERLVQVSSEFEGHPDNAAAAVLGGAVVAWTAAGAGDPRYAAAPIRLHPDIAIFAAV 184 Query 187 PEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAA 246 P+ RSSTAETRVLLP V H DARFN+SRAALLVVALTERPDLLM ATED+LHQPQRAAA Sbjct 185 PQVRSSTAETRVLLPEHVRHTDARFNLSRAALLVVALTERPDLLMEATEDVLHQPQRAAA 244 Query 247 MTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAV 306 M ASAEYL +LRR V A LSGAGP+++ALST++ELP +A+ +GA GFAV ++VG V Sbjct 245 MPASAEYLAMLRRCGVPAVLSGAGPAVLALSTETELPAEALRYGADHGFAVKRMSVGHGV 304 Query 307 RWSPTVRV 314 W+ V V Sbjct 305 SWTSGVAV 312 >gi|229490003|ref|ZP_04383856.1| homoserine kinase [Rhodococcus erythropolis SK121] gi|229323104|gb|EEN88872.1| homoserine kinase [Rhodococcus erythropolis SK121] Length=329 Score = 341 bits (874), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 186/309 (61%), Positives = 224/309 (73%), Gaps = 5/309 (1%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP GL +A V ASSANLGPGFD++GLAL LYDEI+V TTDSGL + V+GEG VP GP Sbjct 20 LPIGLSVTARVPASSANLGPGFDTLGLALGLYDEIVVTTTDSGLQIRVEGEGAADVPWGP 79 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AAGV A+GL V CRNAIPHSRGLGSSA+A VGGLAA NGL D+ Sbjct 80 SHLVVRAIERGLEAAGVWASGLDVLCRNAIPHSRGLGSSASAAVGGLAAANGLARALDAE 139 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDH---SGDRPNYSAVSLRLHPDIRL 182 ++ +L+QL+SEFEGHPDNA+A+VLGGAVVSW+ GD P YSA L +HPDIR Sbjct 140 IGLTEEQLVQLSSEFEGHPDNASASVLGGAVVSWSCPPAVEGDEPIYSAAKLDVHPDIRA 199 Query 183 FTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQ 242 +PE+RSSTA TR LLP V H DA FN SR+AL VVALT RPDLLMAATED LHQ Q Sbjct 200 VALVPEERSSTAHTRGLLPELVPHQDASFNASRSALAVVALTARPDLLMAATEDRLHQAQ 259 Query 243 RAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTV 302 RA A+ + ++ +LR +AA +SGAGP+++ALST+ P + E A G V EL + Sbjct 260 RAPALPLTTRWIGILREAGIAATVSGAGPTVLALSTEP-FPVELAEAARADGLRVLELDI 318 Query 303 GEAVRWSPT 311 + V S T Sbjct 319 ADGVEVSTT 327 >gi|226307407|ref|YP_002767367.1| homoserine kinase [Rhodococcus erythropolis PR4] gi|259494439|sp|C1A1Z3.1|KHSE_RHOE4 RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|226186524|dbj|BAH34628.1| homoserine kinase [Rhodococcus erythropolis PR4] Length=314 Score = 341 bits (874), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 186/309 (61%), Positives = 224/309 (73%), Gaps = 5/309 (1%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP GL +A V ASSANLGPGFD++GLAL LYDEI+V TTDSGL + V+GEG VP GP Sbjct 5 LPIGLSVTARVPASSANLGPGFDTLGLALGLYDEIVVTTTDSGLQIRVEGEGAADVPWGP 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AAGV A+GL V CRNAIPHSRGLGSSA+A VGGLAA NGL D+ Sbjct 65 SHLVVRAIERGLEAAGVWASGLDVLCRNAIPHSRGLGSSASAAVGGLAAANGLARALDAE 124 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDH---SGDRPNYSAVSLRLHPDIRL 182 ++ +L+QL+SEFEGHPDNA+A+VLGGAVVSW+ GD P YSA L +HPDIR Sbjct 125 IGLTEEQLVQLSSEFEGHPDNASASVLGGAVVSWSCPPAVEGDEPIYSAAKLDVHPDIRA 184 Query 183 FTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQ 242 +PE+RSSTA TR LLP V H DA FN SR+AL VVALT RPDLLMAATED LHQ Q Sbjct 185 VALVPEERSSTAHTRGLLPELVPHQDASFNASRSALAVVALTARPDLLMAATEDRLHQAQ 244 Query 243 RAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTV 302 RA A+ + ++ +LR +AA +SGAGP+++ALST+ P + E A G V EL + Sbjct 245 RAPALPLTTRWIGILREAGIAATVSGAGPTVLALSTEP-FPVELAEAARADGLRVLELDI 303 Query 303 GEAVRWSPT 311 + V S T Sbjct 304 ADGVEVSTT 312 >gi|111018487|ref|YP_701459.1| homoserine kinase [Rhodococcus jostii RHA1] gi|110818017|gb|ABG93301.1| homoserine kinase [Rhodococcus jostii RHA1] Length=329 Score = 339 bits (870), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 186/312 (60%), Positives = 230/312 (74%), Gaps = 11/312 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL +A V ASSANLGPGFD++G+AL LYDEI V TT SGL + V+GEG D VP GP Sbjct 20 LPTGLTVTARVPASSANLGPGFDTLGIALGLYDEITVTTTGSGLKIRVEGEGADDVPWGP 79 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL++AGV A GL V CRNAIPHSRGLGSSA+AVVGGLAA NGL ++ D Sbjct 80 SHLVVRAIERGLESAGVWADGLDVVCRNAIPHSRGLGSSASAVVGGLAAANGLAIKLDPE 139 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPN--------YSAVSLRLH 177 S +L+QL+SEFEGHPDNA+A+VLGGAVVSW+ S ++P+ YSAV+L++H Sbjct 140 LGLSLDQLVQLSSEFEGHPDNASASVLGGAVVSWSCAS-EQPDGAPAATDIYSAVALKVH 198 Query 178 PDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDL 237 P IR+ +P +RSSTA TR LLP V H DA FNVSR AL VVALTERPDLLMAATED Sbjct 199 PAIRVVALVPGERSSTAHTRGLLPETVPHRDAAFNVSRGALAVVALTERPDLLMAATEDR 258 Query 238 LHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAV 297 LHQ QRA A+ + ++ +LR+ +AA +SGAGP+++AL+T+ P D A+G V Sbjct 259 LHQTQRAPALPLTTRWIAVLRKAGIAATVSGAGPTVLALTTEP-FPVDLRAQAEAEGLQV 317 Query 298 TELTVGEAVRWS 309 EL V + VR S Sbjct 318 LELDVADGVRTS 329 >gi|325673532|ref|ZP_08153223.1| homoserine kinase [Rhodococcus equi ATCC 33707] gi|325555553|gb|EGD25224.1| homoserine kinase [Rhodococcus equi ATCC 33707] Length=322 Score = 335 bits (858), Expect = 7e-90, Method: Compositional matrix adjust. Identities = 184/307 (60%), Positives = 224/307 (73%), Gaps = 9/307 (2%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL +A V ASSANLGPGFD++GLAL LYDEI V TTDSGLT+ V+GEG D VP GP Sbjct 17 LPAGLTVTARVPASSANLGPGFDTLGLALGLYDEITVTTTDSGLTIRVEGEGADDVPWGP 76 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AAG+ A GL V CRNAIPHSRGLGSSA+A VGGLAA NGL ++ S+ Sbjct 77 SHLVVRAIERGLEAAGLWADGLDVVCRNAIPHSRGLGSSASAAVGGLAAANGLALK--SA 134 Query 127 PS---SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDI 180 P +DA+L+QL+SEFEGHPDNAAA+VLGGAVVSW++ D + +YSAV L +HPD+ Sbjct 135 PELALTDAQLVQLSSEFEGHPDNAAASVLGGAVVSWSEAGADDAAQRSYSAVRLPVHPDV 194 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 R+ +P +RSSTA TR LLP V H DA FNVSR AL VVALT+RPDLLM ATED LHQ Sbjct 195 RVVVLVPSERSSTALTRGLLPETVPHRDAAFNVSRGALAVVALTQRPDLLMTATEDKLHQ 254 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 QRA A+ + ++ LR +AA +SGAGP+++ALS P G V EL Sbjct 255 AQRAPALPLTTTWIAKLRDAGIAATVSGAGPTVLALSV-RPFPDALRREAEESGLRVLEL 313 Query 301 TVGEAVR 307 V + V+ Sbjct 314 EVADGVQ 320 >gi|312139163|ref|YP_004006499.1| homoserine kinase thrb [Rhodococcus equi 103S] gi|311888502|emb|CBH47814.1| homoserine kinase ThrB [Rhodococcus equi 103S] Length=310 Score = 334 bits (857), Expect = 9e-90, Method: Compositional matrix adjust. Identities = 184/307 (60%), Positives = 224/307 (73%), Gaps = 9/307 (2%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL +A V ASSANLGPGFD++GLAL LYDEI V TTDSGLT+ V+GEG D VP GP Sbjct 5 LPAGLTVTARVPASSANLGPGFDTLGLALGLYDEITVTTTDSGLTIRVEGEGADDVPWGP 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AAG+ A GL V CRNAIPHSRGLGSSA+A VGGLAA NGL ++ S+ Sbjct 65 SHLVVRAIERGLEAAGLWADGLDVVCRNAIPHSRGLGSSASAAVGGLAAANGLALK--SA 122 Query 127 PS---SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDI 180 P +DA+L+QL+SEFEGHPDNAAA+VLGGAVVSW++ D + +YSAV L +HPD+ Sbjct 123 PELALTDAQLVQLSSEFEGHPDNAAASVLGGAVVSWSEAGADDAAQRSYSAVRLPVHPDV 182 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 R+ +P +RSSTA TR LLP V H DA FNVSR AL VVALT+RPDLLM ATED LHQ Sbjct 183 RVVVLVPSERSSTALTRGLLPETVPHRDAAFNVSRGALAVVALTQRPDLLMTATEDKLHQ 242 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 QRA A+ + ++ LR +AA +SGAGP+++ALS P G V EL Sbjct 243 AQRAPALPLTTTWIAKLRDAGIAATVSGAGPTVLALSV-RPFPDALRREAEESGLRVLEL 301 Query 301 TVGEAVR 307 V + V+ Sbjct 302 EVADGVQ 308 >gi|226360610|ref|YP_002778388.1| homoserine kinase [Rhodococcus opacus B4] gi|254807823|sp|C1AW13.1|KHSE_RHOOB RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|226239095|dbj|BAH49443.1| homoserine kinase [Rhodococcus opacus B4] Length=314 Score = 334 bits (856), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 183/312 (59%), Positives = 229/312 (74%), Gaps = 11/312 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL +A V ASSANLGPGFD++G+AL LYDEI V TT SGL + V+GEG D VP GP Sbjct 5 LPAGLTVTARVPASSANLGPGFDTLGIALGLYDEITVTTTASGLNIRVEGEGADDVPWGP 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL++AGV A GL V CRN IPHSRGLGSSA+AVVGGLAA NGL ++ D Sbjct 65 SHLVVRAIERGLESAGVWADGLDVVCRNVIPHSRGLGSSASAVVGGLAAANGLAIKLDPE 124 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPN--------YSAVSLRLH 177 S +L+QL+SEFEGHPDNA+A+VLGGAVVSW+ +G++ + YSAV+L++H Sbjct 125 LGLSLDQLVQLSSEFEGHPDNASASVLGGAVVSWS-CAGEQADGAPAATDIYSAVALKVH 183 Query 178 PDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDL 237 P IR+ +P +RSSTA TR LLP V H DA FNVSR AL VVALTERPDLLMAATED Sbjct 184 PAIRVVALVPGERSSTAHTRGLLPETVPHRDAAFNVSRGALAVVALTERPDLLMAATEDR 243 Query 238 LHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAV 297 LHQ QRA A+ + ++ +LR+ +AA +SGAGP+++AL+T+ P + A+G V Sbjct 244 LHQTQRAPALPLTTRWIAVLRKAGIAATVSGAGPTVLALTTEP-FPVELRAQAEAEGLQV 302 Query 298 TELTVGEAVRWS 309 EL V + VR S Sbjct 303 LELDVADGVRTS 314 >gi|169628528|ref|YP_001702177.1| homoserine kinase [Mycobacterium abscessus ATCC 19977] gi|226729708|sp|B1MLU6.1|KHSE_MYCA9 RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|169240495|emb|CAM61523.1| Probable homoserine kinase (ThrB) [Mycobacterium abscessus] Length=306 Score = 321 bits (823), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 186/301 (62%), Positives = 228/301 (76%), Gaps = 1/301 (0%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP+GL + +V ASSANLGPGFDS+G+ALSLYDEI V TT+SGL V V+G+G +VPL Sbjct 4 VLPAGLATTVLVPASSANLGPGFDSLGIALSLYDEIEVNTTESGLKVAVEGQGAGEVPLD 63 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 HLVVRA++ GL A G +A GL V+C N IPHSRGLGSSAAA V GL NGL+ + Sbjct 64 GSHLVVRAIERGLAAGGAAAPGLIVQCHNKIPHSRGLGSSAAAAVAGLGVANGLLAKAGR 123 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 + SD L+QLASEFEGHPDNAAA+VLGGAVVSW++ SG P Y+A L +HPDI++ A Sbjct 124 AVLSDDVLVQLASEFEGHPDNAAASVLGGAVVSWSETSGATPIYAATRLDVHPDIKIVAA 183 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 IPE++SSTA TRVLLP V+H DARFN+SR ALL VALT RPDLLM ATED LHQPQRA+ Sbjct 184 IPEEQSSTAHTRVLLPQAVTHVDARFNISRVALLTVALTARPDLLMTATEDRLHQPQRAS 243 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ASA+ L LR VAA LSGAGP+++AL+T +LP AV++ +GF++ + V Sbjct 244 AMPASADVLAYLRSQGVAAVLSGAGPAVLALTT-VDLPDSAVKYAEDQGFSLVAMAVSAG 302 Query 306 V 306 V Sbjct 303 V 303 >gi|333920932|ref|YP_004494513.1| Homoserine kinase [Amycolicicoccus subflavus DQS3-9A1] gi|333483153|gb|AEF41713.1| Homoserine kinase [Amycolicicoccus subflavus DQS3-9A1] Length=325 Score = 307 bits (786), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 173/314 (56%), Positives = 217/314 (70%), Gaps = 15/314 (4%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP GL A+A V ASSANLGPGFDS+G+AL L D I V T +GL ++V+G G +VPL Sbjct 13 VLPDGLTATAEVPASSANLGPGFDSLGIALGLNDTIGVTTAPAGLEISVEGAGAGEVPLD 72 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 HLV +AV GL AAGV+ GL + C+N IPHSRGLGSSA+A VGGL A NGLV Q Sbjct 73 DSHLVAKAVFRGLGAAGVTPKGLRITCKNTIPHSRGLGSSASAAVGGLVAANGLVAQF-- 130 Query 126 SPS---SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---------RPNYSAVS 173 +P +D +L+QLASEFEGHPDNA+A+VLGGAVVSWT + D +Y A Sbjct 131 APDRVLTDDQLVQLASEFEGHPDNASASVLGGAVVSWTQAADDSSPIAGCTAECSYFATR 190 Query 174 LRLHPDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAA 233 L +HPDIR +PE RSST++TR +LP V+H DA FNVSRAAL VVALT RP+LL+AA Sbjct 191 LEVHPDIRAVVLVPETRSSTSQTRGILPTHVTHRDAVFNVSRAALAVVALTTRPELLLAA 250 Query 234 TEDLLHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAK 293 TED LHQ QRA A+ + ++ LLR + A +SGAGP+++AL T ++P V A+ Sbjct 251 TEDRLHQAQRAPAIPLTTRWVSLLRGAGIPATVSGAGPAVLAL-TVRDIPAALVRRAGAE 309 Query 294 GFAVTELTVGEAVR 307 G AV ELT+ + R Sbjct 310 GLAVHELTIADGAR 323 >gi|54023018|ref|YP_117260.1| homoserine kinase [Nocardia farcinica IFM 10152] gi|59798149|sp|Q5Z0Z5.1|KHSE_NOCFA RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|54014526|dbj|BAD55896.1| putative homoserine kinase [Nocardia farcinica IFM 10152] Length=315 Score = 306 bits (783), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 183/309 (60%), Positives = 215/309 (70%), Gaps = 10/309 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL +A V ASSANLGPGFDS+G+AL +YDEI V TTDSGLT+ V+GEG D VP GP Sbjct 5 LPAGLTVTARVPASSANLGPGFDSLGMALGIYDEIEVRTTDSGLTIRVEGEGADDVPWGP 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+ AGV A GL V CRN IPHSRGLGSSA+AVVGGLAA L + D S Sbjct 65 SHLVVRAIERGLEHAGVWADGLDVVCRNVIPHSRGLGSSASAVVGGLAAGCALAAKLDES 124 Query 127 PSSDA-ELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDR----PN----YSAVSLRLH 177 ++ A EL+QLASEFEGHPDNAAA+VLGG VVSWT+ S + P+ Y AV L H Sbjct 125 LATAADELVQLASEFEGHPDNAAASVLGGIVVSWTETSAEAQAEVPDHGRVYRAVRLDPH 184 Query 178 PDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDL 237 P +R IPE RSSTA TR LLP V H DA FNVSRAAL VVALT RPDLLM AT D Sbjct 185 PTLRPVVLIPEVRSSTAHTRGLLPESVPHGDAAFNVSRAALAVVALTTRPDLLMPATADR 244 Query 238 LHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAV 297 LHQ QRA A+ + ++ LR + A +SGAGP+++AL T E P + A +G V Sbjct 245 LHQAQRAPALPLTTRWIDRLRAAGIPATVSGAGPTVLALGT-GEFPAELRALAAEEGLRV 303 Query 298 TELTVGEAV 306 E + E V Sbjct 304 VEPGLAEGV 312 >gi|319948890|ref|ZP_08023002.1| homoserine kinase [Dietzia cinnamea P4] gi|319437449|gb|EFV92457.1| homoserine kinase [Dietzia cinnamea P4] Length=320 Score = 290 bits (741), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 160/302 (53%), Positives = 205/302 (68%), Gaps = 5/302 (1%) Query 6 LLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLG 65 +LP G + V ASSANLGPGFD++G+AL LYD I V SGL + V GEG QVP Sbjct 19 ILPVGRTVTIEVPASSANLGPGFDALGVALGLYDTITVTVIASGLELEVSGEGAGQVPED 78 Query 66 PEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDS 125 HLV +AV+ GL+A GV A G+ + C N+IPHSRGLGSSA+A VGGL A NGL+ D Sbjct 79 ASHLVAKAVEAGLRAGGVGAPGVRISCSNSIPHSRGLGSSASAAVGGLVAANGLM---DG 135 Query 126 SPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 + S+D L+QLASEFEGHPDNAAA+VLGG VVSWT+ S D +Y AV + + P I Sbjct 136 ALSTD-HLVQLASEFEGHPDNAAASVLGGVVVSWTERSSDGVHYRAVRMEVDPSIVATVL 194 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 +P + SSTA+TR LLPA V H+DA FN SRAAL+ VAL P+ L+AATED LHQ RA Sbjct 195 VPSETSSTAQTRGLLPATVPHEDAAFNASRAALMSVALASHPEHLLAATEDRLHQSYRAP 254 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 A+ + E++ LR +AA +SGAGP+++ L T + LP+D E +G+ V +L + + Sbjct 255 ALVGTTEWVTRLRERGLAATVSGAGPTVLVLGTGA-LPSDLRELAERQGWTVRDLEIADG 313 Query 306 VR 307 R Sbjct 314 AR 315 >gi|296138959|ref|YP_003646202.1| homoserine kinase [Tsukamurella paurometabola DSM 20162] gi|296027093|gb|ADG77863.1| homoserine kinase [Tsukamurella paurometabola DSM 20162] Length=330 Score = 275 bits (702), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 173/327 (53%), Positives = 210/327 (65%), Gaps = 22/327 (6%) Query 4 QALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVP 63 Q LPSGL A+ V ASSANLGPGFD++GLAL LYD++ VETTD GL +TVDGEG D VP Sbjct 5 QHTLPSGLAATVTVPASSANLGPGFDTLGLALGLYDDVTVETTDGGLEITVDGEGADDVP 64 Query 64 LGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQT 123 L HLVV A++ L G SA GL + C N IPHSRGLGSSAAA V G+AA L Sbjct 65 LDERHLVVVALRRTLAHLGTSAPGLKLHCVNRIPHSRGLGSSAAAAVAGIAAAAALAADA 124 Query 124 DSSPS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWT-------DHSGDRPN------- 168 D + + AE++QLASEFEGHPDNA+A+VLGGAVV+WT D +G R Sbjct 125 DFPRALTAAEMVQLASEFEGHPDNASASVLGGAVVAWTVPAAPVPDSAGYRDQSLGHGQA 184 Query 169 ------YSAVSLRLHPDIRLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVA 222 Y A + +HPDIR + +P+ +SST+ TR +LP V H DA FN SRAAL+V+A Sbjct 185 ASGPTRYDARRVDVHPDIRAYAFVPDVQSSTSVTRGMLPRLVPHADAAFNASRAALMVLA 244 Query 223 LTERPDLLMAATEDLLHQPQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSEL 282 LT PDLL+ ATED LHQ RAA+M S + LR VAAA+SGAGP+++AL T L Sbjct 245 LTAHPDLLLDATEDRLHQRYRAASMKDSFGLVERLRAGGVAAAISGAGPTVLAL-TPEPL 303 Query 283 PTDAVEFGAAKGFAVTELTVGEAVRWS 309 P E GF V EL + + V S Sbjct 304 PAALAESAEHAGFTVHELVIADGVSRS 330 >gi|336325983|ref|YP_004605949.1| Homoserine kinase [Corynebacterium resistens DSM 45100] gi|336101965|gb|AEI09785.1| Homoserine kinase [Corynebacterium resistens DSM 45100] Length=308 Score = 270 bits (691), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 154/307 (51%), Positives = 198/307 (65%), Gaps = 14/307 (4%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 +P G A+ + ASSANLGPGFD++GLAL LYD + VE TD+ L V V GEG +VPL Sbjct 5 IPVGRKATVKIPASSANLGPGFDTLGLALGLYDHVTVEVTDAPLVVEVTGEGQGEVPLDE 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AA VS GL V C N+IP SRGLGSSA+A V G+ A NGL Sbjct 65 SHLVVRAIRAGLKAADVSVRGLKVTCHNSIPQSRGLGSSASAAVAGVCAANGLA----GF 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P D +L+QLAS FEGHPDNAAA++LGGAVVSWT+ D P + AV +++H I+ Sbjct 121 PLGDDQLVQLASAFEGHPDNAAASILGGAVVSWTNVPIDGHSEPKHYAVGVKVHEAIKAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P+ +ST R +LP+ VSH DARFNVSR A++ +AL P LL T D LHQ R Sbjct 181 AFVPDFHASTEAVRRVLPSDVSHLDARFNVSRTAVMTIALQHDPSLLWEGTRDRLHQTYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALST---DSELPTDAVEFGAAKGFAVTEL 300 A + +AE++ LR A LSGAGP+++ LST D +L +A+E +G V EL Sbjct 241 AEVLPITAEWVNRLRNLGYPAFLSGAGPTIMVLSTEDVDQKLKDEAIE----RGIRVLEL 296 Query 301 TVGEAVR 307 V V+ Sbjct 297 EVAGPVQ 303 >gi|334563586|ref|ZP_08516577.1| homoserine kinase [Corynebacterium bovis DSM 20582] Length=309 Score = 266 bits (679), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 159/290 (55%), Positives = 198/290 (69%), Gaps = 10/290 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 +P G A+ V ASSANLGPGFD++GLAL L+D + VE TDSGL V V GEG +VPL Sbjct 5 IPVGRTATVTVPASSANLGPGFDTLGLALGLHDIVTVEVTDSGLVVEVMGEGEGEVPLDE 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+AA V+ GL V C+NA+PH+RGLGSSA+A V G+AA NGL Sbjct 65 RHLVVRALREGLRAADVTVRGLRVTCQNAVPHARGLGSSASAAVAGVAAANGLA----GG 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 SDA++IQ+AS FEGHPDNAAA+VLGGAVVSWT D P Y AV L +HPDIR Sbjct 121 VLSDADMIQVASSFEGHPDNAAASVLGGAVVSWTHRPVDGRSTPEYQAVHLDVHPDIRAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P+ +ST R +LP+ VSH+DARFNVSR A++ VAL P+LL+ T D LHQ R Sbjct 181 ALVPDFHASTDAVRRVLPSDVSHEDARFNVSRTAVMTVALQSHPELLLEGTRDRLHQTYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALST---DSELPTDAVEFG 290 A + +AE++ LR AA LSGAGP+++ LST D + DA E G Sbjct 241 AEVLPVTAEWVNRLRNRGYAAFLSGAGPTVLVLSTGPVDPAILADAEEQG 290 >gi|237785872|ref|YP_002906577.1| homoserine kinase [Corynebacterium kroppenstedtii DSM 44385] gi|259494432|sp|C4LJM9.1|KHSE_CORK4 RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|237758784|gb|ACR18034.1| Homoserine kinase [Corynebacterium kroppenstedtii DSM 44385] Length=310 Score = 265 bits (677), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 156/299 (53%), Positives = 198/299 (67%), Gaps = 8/299 (2%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 +P G + V ASSANLGPGFD++GLA+ LYD + VE T SGLTV V GEG +VPL Sbjct 5 IPVGRSVTVRVPASSANLGPGFDTLGLAVGLYDIVTVEVTASGLTVDVQGEGAGEVPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA++ GL+ A GLAV C NAIP SRGLGSSAAA G+ A N L ++ Sbjct 65 THLVVRAIREGLRVAHADVPGLAVSCENAIPQSRGLGSSAAAAAAGVCAANALADNALTT 124 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 ++IQ+ S FEGHPDNAAA+VLGGAVVSWTD D P Y A+ + +HPDIR Sbjct 125 ----DQVIQVVSSFEGHPDNAAASVLGGAVVSWTDTPVDGETAPQYHAIGVDVHPDIRAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 IP+ +ST R +LP+ VSH DARFNVSR A++ VAL P+LL T D LHQP R Sbjct 181 AFIPDFTASTNAVRRVLPSDVSHVDARFNVSRTAVMTVALRTNPELLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTV 302 A A++ SAE++ LR AA LSGAGP+++ LST+ +LP + V+ +++G V L + Sbjct 241 ADALSVSAEWVNRLRNRGYAAYLSGAGPTIMVLSTE-DLPAEIVDTASSEGLRVITLPI 298 >gi|326382078|ref|ZP_08203771.1| homoserine kinase [Gordonia neofelifaecis NRRL B-59395] gi|326199504|gb|EGD56685.1| homoserine kinase [Gordonia neofelifaecis NRRL B-59395] Length=316 Score = 256 bits (653), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 161/292 (56%), Positives = 192/292 (66%), Gaps = 5/292 (1%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP GL V ASSANLGPGFD +GLALS+YDE+ V TD G+TV V GE DQVPL Sbjct 16 LPEGLSVRVRVPASSANLGPGFDCLGLALSIYDEVAVTVTDGGITVAVSGEAADQVPLDE 75 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLV RAV G + AGV+ G + CRNAIPHSRGLGSSAAAVVGGLAA + LV + Sbjct 76 RHLVARAVVRGFETAGVAVRGFHLECRNAIPHSRGLGSSAAAVVGGLAAASALVARDGRR 135 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 P+ DA+++QL+SEFEGHPDNAAA+VLG AVV+WT G+R + A L LHP + Sbjct 136 PALDDAQMVQLSSEFEGHPDNAAASVLGSAVVTWT--HGER-EFFARRLDLHPAVVATVF 192 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 +PE SST TR LLP V DA FNVSRAAL VVALT P+ L+ AT+D LHQ RA Sbjct 193 VPEVESSTEATRGLLPDAVPRTDAVFNVSRAALGVVALTAAPECLIDATQDRLHQEYRAQ 252 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAV 297 A+ + + LR AA +SGAGPS++ L T+ L E A GF + Sbjct 253 ALPETTRLVGSLREGGHAATVSGAGPSVLVLGTNP-LGAQEAELAADLGFTM 303 >gi|305681844|ref|ZP_07404648.1| homoserine kinase [Corynebacterium matruchotii ATCC 14266] gi|305658317|gb|EFM47820.1| homoserine kinase [Corynebacterium matruchotii ATCC 14266] Length=308 Score = 255 bits (652), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 157/306 (52%), Positives = 196/306 (65%), Gaps = 12/306 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP G + V ASSANLGPGFD++GLAL+LYD + VE SGL V V GEG ++PL Sbjct 5 LPVGTKVTVTVPASSANLGPGFDTLGLALALYDTVEVEVISSGLEVEVFGEGHGELPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVV+A++ GL+A A GL V C N IP SRGLGSSAAA V G+AA NGL Sbjct 65 SHLVVKALRAGLKACDAIAPGLRVVCHNVIPQSRGLGSSAAAAVAGVAAANGLC----GF 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P DA+++QL+S FEGHPDNAAA+VLGGAVVSWT+ D P Y AV + +HP+I Sbjct 121 PLDDAQVVQLSSAFEGHPDNAAASVLGGAVVSWTEIPVDGRTEPQYKAVGIPVHPNILAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P +ST R +LP+ V+H DARFNVSR A++ VAL P+LL T D LHQP R Sbjct 181 ALVPNFHASTEAVRRVLPSDVTHLDARFNVSRCAVMTVALQHHPELLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAK--GFAVTELT 301 A + +AE++ LR AA LSGAGP+++ LST+ P D G A+ G V L Sbjct 241 ADVLPITAEWVNRLRNRGYAAYLSGAGPTVMVLSTE---PIDEAILGEAREAGLTVHHLD 297 Query 302 VGEAVR 307 V E V+ Sbjct 298 VAEPVK 303 >gi|145295323|ref|YP_001138144.1| homoserine kinase [Corynebacterium glutamicum R] gi|166220502|sp|A4QDE5.1|KHSE_CORGB RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|39588|emb|CAA68332.1| unnamed protein product [Corynebacterium glutamicum] gi|140845243|dbj|BAF54242.1| hypothetical protein [Corynebacterium glutamicum R] gi|344045703|gb|EGV41373.1| homoserine kinase [Corynebacterium glutamicum S9114] Length=309 Score = 255 bits (651), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 153/301 (51%), Positives = 195/301 (65%), Gaps = 8/301 (2%) Query 10 GLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGPEHL 69 G + V SSANLGPGFD++GLALS+YD + VE SGL V V GEG +VPL HL Sbjct 8 GRKVTVTVPGSSANLGPGFDTLGLALSVYDTVEVEIIPSGLEVEVFGEGQGEVPLDGSHL 67 Query 70 VVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSSPSS 129 VV+A++ GL+AA GL V C N IP SRGLGSSAAA V G+AA NGL P + Sbjct 68 VVKAIRAGLKAADAEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLA----DFPLT 123 Query 130 DAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLFTAI 186 +++QL+S FEGHPDNAAA+VLGGAVVSWT+ S D +P Y+AV L + +IR + Sbjct 124 QEQIVQLSSAFEGHPDNAAASVLGGAVVSWTNLSIDGKSQPQYAAVPLEVQDNIRATALV 183 Query 187 PEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAA 246 P +ST R +LP +V+H DARFNVSR A+++VAL +RPDLL T D LHQP RA Sbjct 184 PNFHASTEAVRRVLPTEVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYRAEV 243 Query 247 MTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAV 306 + ++E++ LR AA LSGAGP+ + LST+ +P +E G V EL V V Sbjct 244 LPVTSEWVNRLRNRGYAAYLSGAGPTAMVLSTEP-IPDKVLEDARESGIKVLELEVAGPV 302 Query 307 R 307 + Sbjct 303 K 303 >gi|19552408|ref|NP_600410.1| homoserine kinase [Corynebacterium glutamicum ATCC 13032] gi|62390072|ref|YP_225474.1| homoserine kinase [Corynebacterium glutamicum ATCC 13032] gi|14916940|sp|P07128.4|KHSE_CORGL RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|40504|emb|CAA68615.1| unnamed protein product [Corynebacterium glutamicum] gi|21323951|dbj|BAB98577.1| Homoserine kinase [Corynebacterium glutamicum ATCC 13032] gi|41325408|emb|CAF19888.1| Homoserine Kinase [Corynebacterium glutamicum ATCC 13032] Length=309 Score = 254 bits (650), Expect = 9e-66, Method: Compositional matrix adjust. Identities = 153/301 (51%), Positives = 195/301 (65%), Gaps = 8/301 (2%) Query 10 GLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGPEHL 69 G + V SSANLGPGFD++GLALS+YD + VE SGL V V GEG +VPL HL Sbjct 8 GRKVTVTVPGSSANLGPGFDTLGLALSVYDTVEVEIIPSGLEVEVFGEGQGEVPLDGSHL 67 Query 70 VVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSSPSS 129 VV+A++ GL+AA GL V C N IP SRGLGSSAAA V G+AA NGL P + Sbjct 68 VVKAIRAGLKAADAEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLA----DFPLT 123 Query 130 DAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLFTAI 186 +++QL+S FEGHPDNAAA+VLGGAVVSWT+ S D +P Y+AV L + +IR + Sbjct 124 QEQIVQLSSAFEGHPDNAAASVLGGAVVSWTNLSIDGKSQPQYAAVPLEVQDNIRATALV 183 Query 187 PEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAAA 246 P +ST R +LP +V+H DARFNVSR A+++VAL +RPDLL T D LHQP RA Sbjct 184 PNFHASTEAVRRVLPTEVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYRAEV 243 Query 247 MTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEAV 306 + ++E++ LR AA LSGAGP+ + LST+ +P +E G V EL V V Sbjct 244 LPITSEWVNRLRNRGYAAYLSGAGPTAMVLSTEP-IPDKVLEDARESGIKVLELEVAGPV 302 Query 307 R 307 + Sbjct 303 K 303 >gi|225022818|ref|ZP_03712010.1| hypothetical protein CORMATOL_02863 [Corynebacterium matruchotii ATCC 33806] gi|224944425|gb|EEG25634.1| hypothetical protein CORMATOL_02863 [Corynebacterium matruchotii ATCC 33806] Length=308 Score = 254 bits (648), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 156/306 (51%), Positives = 196/306 (65%), Gaps = 12/306 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP G + V ASSANLGPGFD++GLAL+LYD + VE SGL V V GEG D++PL Sbjct 5 LPVGTKVTVTVPASSANLGPGFDTLGLALALYDTVEVEVIPSGLKVEVFGEGHDELPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVV+A++ GL+A A GL V C N IP SRGLGSSAAA V G+AA NGL Sbjct 65 SHLVVKALRAGLKACDAIAPGLRVVCHNVIPQSRGLGSSAAAAVAGVAAANGLC----GF 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P DA+++QL+S FEGHPDNAAA+VLG AVVSWT+ D P Y AV + +HP+I Sbjct 121 PLDDAQVVQLSSAFEGHPDNAAASVLGDAVVSWTEIPVDGRTEPQYKAVGIPVHPNILAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P +ST R +LP+ V+H DARFNVSR A++ VAL P+LL T D LHQP R Sbjct 181 ALVPSFHASTEAVRRVLPSDVTHLDARFNVSRCAVMTVALQHHPELLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAK--GFAVTELT 301 A + +AE++ LR AA LSGAGP+++ LST+ P D G A+ G V L Sbjct 241 ADVLPITAEWVNRLRNRGYAAYLSGAGPTVMVLSTE---PVDEAILGEAREAGLTVHHLD 297 Query 302 VGEAVR 307 V + V+ Sbjct 298 VAKPVK 303 >gi|25027846|ref|NP_737900.1| homoserine kinase [Corynebacterium efficiens YS-314] gi|259506238|ref|ZP_05749140.1| homoserine kinase [Corynebacterium efficiens YS-314] gi|59798418|sp|Q8FQ44.1|KHSE_COREF RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|23493129|dbj|BAC18100.1| putative homoserine kinase [Corynebacterium efficiens YS-314] gi|259166215|gb|EEW50769.1| homoserine kinase [Corynebacterium efficiens YS-314] Length=309 Score = 254 bits (648), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 158/307 (52%), Positives = 198/307 (65%), Gaps = 14/307 (4%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 L G + V SSANLGPGFD++GLALS+YD + VE SGL V V GEG +VPL Sbjct 5 LNVGRKVTVTVPGSSANLGPGFDTLGLALSVYDTVEVEIIQSGLEVEVFGEGQGEVPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVV+A++ GL+ A GL V C N IP SRGLGSSAAA V G+AA NGL Sbjct 65 SHLVVKAIRSGLKTADAEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLA----GF 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P + +++QLAS FEGHPDNAAA+VLGGAVVSWT+ D +P YSAV L +H IR Sbjct 121 PLTQEQVVQLASAFEGHPDNAAASVLGGAVVSWTNLPVDGKSQPEYSAVGLDVHEGIRAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P+ +ST R +LP+ V+H DARFNVSR A+++VAL +RPDLL T D LHQP R Sbjct 181 ALVPDFHASTEAVRRVLPSDVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTD---SELPTDAVEFGAAKGFAVTEL 300 A + +AE++ LR AA LSGAGP+++ LST+ ++ DA E G V EL Sbjct 241 ADVLPVTAEWVNRLRNRGYAAYLSGAGPTVMVLSTEPVSDKILDDARE----AGLRVIEL 296 Query 301 TVGEAVR 307 V + VR Sbjct 297 EVADPVR 303 >gi|172040375|ref|YP_001800089.1| homoserine kinase [Corynebacterium urealyticum DSM 7109] gi|226729691|sp|B1VFW6.1|KHSE_CORU7 RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|171851679|emb|CAQ04655.1| unnamed protein product [Corynebacterium urealyticum DSM 7109] Length=306 Score = 253 bits (645), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 156/303 (52%), Positives = 192/303 (64%), Gaps = 17/303 (5%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 +P G V SSANLGPGFDS+GLALS+YD + VE DSGL V V GEG +VPL Sbjct 5 IPVGRKVRVKVPGSSANLGPGFDSLGLALSIYDHVEVEVIDSGLEVEVTGEGQGEVPLDE 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGL---VVQT 123 HLVVRA++ GL+ A V A GL VRC N+IP SRGLGSSAAA V G+ A N L V+ T Sbjct 65 RHLVVRAIRAGLKKADVIARGLRVRCNNSIPQSRGLGSSAAAAVSGVVAANALAGDVLDT 124 Query 124 DSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDH--SGDRPNYSAVSLRLHPDIR 181 D+ +IQLAS FEGHPDN AA+VLG AVVSWT+ G P Y A + +HPDIR Sbjct 125 DT-------IIQLASTFEGHPDNVAASVLGSAVVSWTNIPVDGTEPTYHASPVTVHPDIR 177 Query 182 LFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQP 241 IP +ST R +LP+ + H DARFNVSR +L+VAL++ P LL T D +HQP Sbjct 178 ATALIPNSHASTEAVRRVLPSDIPHLDARFNVSRTGVLLVALSKDPSLLWEGTRDRMHQP 237 Query 242 QRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAA--KGFAVTE 299 RA + S+E++ LR A LSGAGP+++ LST+ P + A +G V E Sbjct 238 FRAEVLPISSEWVNRLRNQGYPAFLSGAGPTVLVLSTE---PVEEALLQEARDRGIRVEE 294 Query 300 LTV 302 LTV Sbjct 295 LTV 297 >gi|343928054|ref|ZP_08767519.1| homoserine kinase [Gordonia alkanivorans NBRC 16433] gi|343762062|dbj|GAA14445.1| homoserine kinase [Gordonia alkanivorans NBRC 16433] Length=334 Score = 252 bits (643), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 159/304 (53%), Positives = 197/304 (65%), Gaps = 2/304 (0%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP G+ A V ASSANLGPGFD +G+AL +YDE+IVET D G+ + V+GEG VP Sbjct 30 LPVGVSARVRVPASSANLGPGFDCLGIALGIYDEVIVETVDDGIVLDVEGEGSADVPRDE 89 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVVRA+ GL AGVSA GL +RC N IPHSRGLGSSAAA V GLAA +GL+ Sbjct 90 SHLVVRALNRGLTHAGVSAPGLKLRCVNQIPHSRGLGSSAAAAVSGLAAASGLISAAGFG 149 Query 127 PS-SDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGDRPNYSAVSLRLHPDIRLFTA 185 S EL+QL+SEFEGHPDNAAA+VLG VV+WT+ + D +Y A L +HPD+ Sbjct 150 AGLSTDELVQLSSEFEGHPDNAAASVLGSVVVTWTETADDVNSYHAHRLSVHPDVCATVF 209 Query 186 IPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQRAA 245 +P+ SST+ TR LLP V DA FN+SRAAL VVALT P LMAA+ D LHQP RA+ Sbjct 210 VPDTESSTSFTRGLLPDAVPRADAVFNLSRAALAVVALTSDPRNLMAASADRLHQPYRAS 269 Query 246 AMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTVGEA 305 AM ++E + LR AA +SGAGP+++ L T + +P D GF + + Sbjct 270 AMVPTSELVAELRARGHAATVSGAGPTVLVLGT-APIPADIRVLAQGLGFTTHSVAIAGG 328 Query 306 VRWS 309 V S Sbjct 329 VDIS 332 >gi|227547997|ref|ZP_03978046.1| homoserine kinase [Corynebacterium lipophiloflavum DSM 44291] gi|227079903|gb|EEI17866.1| homoserine kinase [Corynebacterium lipophiloflavum DSM 44291] Length=309 Score = 249 bits (637), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 146/299 (49%), Positives = 191/299 (64%), Gaps = 8/299 (2%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP+GL A+ V SSANLGPGFD++G+AL +YD + VET SGL + + GEG D +P Sbjct 5 LPTGLKATVTVPGSSANLGPGFDTLGIALGIYDTVEVETIPSGLEIEIFGEGADDLPRDS 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLV++A+ GL+ AGV GL V C N IP SRGLGSSA+A V G+ A N L S Sbjct 65 SHLVIKAIHSGLEVAGVEVPGLRVVCHNEIPQSRGLGSSASAAVAGVVAANTLA----GS 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P A L+QL+S FEGHPDNAAA+VLGGAVVSWTD D Y AV +++HP IR Sbjct 121 PLDAAALVQLSSAFEGHPDNAAASVLGGAVVSWTDVPVDGVTDTTYRAVGVQVHPSIRAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P+ +ST R +LP+ V+H DARFNVSR A++ VA+ P+LL + D LHQP R Sbjct 181 AFVPDFHASTDAVRQVLPSHVTHTDARFNVSRTAVMTVAIQHHPELLWEGSRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTELTV 302 A + +AE++ LR AA LSGAGP+ + LST+ +P ++ G V +L + Sbjct 241 ADVLPVTAEWVNHLRNRGFAAYLSGAGPTAMVLSTEP-VPEKILDGARQAGLRVVDLDI 298 >gi|337290506|ref|YP_004629527.1| Homoserine kinase [Corynebacterium ulcerans BR-AD22] gi|334698812|gb|AEG83608.1| Homoserine kinase [Corynebacterium ulcerans BR-AD22] Length=307 Score = 249 bits (635), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 149/290 (52%), Positives = 185/290 (64%), Gaps = 10/290 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 L G S V ASSANLGPGFD++GLA+SLYD + VE SGL+V V GEG ++PL Sbjct 5 LEVGKKVSVTVPASSANLGPGFDTLGLAVSLYDTVEVEVVASGLSVEVFGEGQGELPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVV+A++ GL+AA A GL V C N+IP SRGLGSSAAA G+ A NGL Sbjct 65 SHLVVKALRAGLKAADAHAPGLKVVCHNSIPQSRGLGSSAAAAAAGVCAANGLA----GC 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P SD +L+QL+S FEGHPDNAAA+VLG AVVSWT+ D P Y AV++ + I Sbjct 121 PLSDEQLVQLSSAFEGHPDNAAASVLGQAVVSWTEIPVDGKTEPQYRAVTIPVAESIMAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P +ST R +LP V+H DARFNVSR A++ VAL P+LL T D LHQP R Sbjct 181 ALVPNFHASTEAVRRVLPTDVTHLDARFNVSRCAVMTVALQHHPELLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALST---DSELPTDAVEFG 290 A + +AE++ LR AA LSGAGP+++ LST D + DA E G Sbjct 241 ADVLPVTAEWVNRLRNRGYAAYLSGAGPTVMVLSTEPVDESMLNDACEAG 290 >gi|38233632|ref|NP_939399.1| homoserine kinase [Corynebacterium diphtheriae NCTC 13129] gi|59798309|sp|Q6NHU3.1|KHSE_CORDI RecName: Full=Homoserine kinase; Short=HK; Short=HSK gi|38199892|emb|CAE49558.1| homoserine kinase [Corynebacterium diphtheriae] Length=308 Score = 248 bits (634), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 154/305 (51%), Positives = 194/305 (64%), Gaps = 12/305 (3%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 LP G + V ASSANLGPGFD++GLALSLYD + VE TD GL V V GEG ++PL Sbjct 5 LPVGKKVTVTVPASSANLGPGFDTLGLALSLYDTVEVEVTDHGLEVEVFGEGQGELPLDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQTDSS 126 HLVV+A++ GL+AA V GL V C N IP SRGLGSSAAA V G+AA NGL Sbjct 65 SHLVVKAIRAGLKAADVQVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLA----GF 120 Query 127 PSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDIRLF 183 P DA ++QL+S FEGHPDNAAA+VLG AVVSWT+ D P + AV++ + I+ Sbjct 121 PLDDARVVQLSSAFEGHPDNAAASVLGNAVVSWTEIPVDGRTEPQFKAVTINVDSRIKAT 180 Query 184 TAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQPQR 243 +P+ +ST R +LP+ V+H DARFNVSR A++ VAL P+LL T D LHQP R Sbjct 181 ALVPDFHASTEAVRRVLPSDVTHLDARFNVSRCAVMTVALQHHPELLWEGTRDRLHQPYR 240 Query 244 AAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAK--GFAVTELT 301 A + +AE++ LR AA LSGAGP+++ L T+ P D A+ G V L Sbjct 241 ADVLPVTAEWVNRLRNRGYAAYLSGAGPTIMVLHTE---PVDEAVLNDAREAGLRVLSLD 297 Query 302 VGEAV 306 V +AV Sbjct 298 VADAV 302 >gi|213964485|ref|ZP_03392685.1| homoserine kinase [Corynebacterium amycolatum SK46] gi|213952678|gb|EEB64060.1| homoserine kinase [Corynebacterium amycolatum SK46] Length=308 Score = 246 bits (628), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 155/310 (50%), Positives = 196/310 (64%), Gaps = 15/310 (4%) Query 4 QALLPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVP 63 Q L P G + VA SSANLGPGFD++GLA++LYD + VE +SG+ V + GEG +P Sbjct 3 QELFP-GQKVTVTVAGSSANLGPGFDTLGLAVALYDIVEVEVIESGVVVEIHGEGEVDLP 61 Query 64 LGPEHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGLVVQT 123 +LVVRA++ GL+AAGV A GL V C N IP SRGLGSSAAA V G+AA NGL Sbjct 62 RNESNLVVRAIRAGLRAAGVEAPGLKVICHNTIPQSRGLGSSAAAAVAGVAAANGLA--- 118 Query 124 DSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDI 180 P +D ++IQ +S FEGHPDNA A+VLGGAVVSWTD D P Y AVS+ +H I Sbjct 119 -GFPLTDDQVIQESSVFEGHPDNAGASVLGGAVVSWTDKPVDGRTAPQYRAVSIPVHESI 177 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 + +P +ST R +LP+ VSH DARFNVSR A++ AL P+LL T D LHQ Sbjct 178 QATALVPAFHASTNAVRQVLPSDVSHVDARFNVSRTAVMTAALQSHPELLWEGTRDRLHQ 237 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALST---DSELPTDAVEFGAAKGFAV 297 P R+ + +AE++ LR AA LSGAGP+ + L T D ++ DA E G V Sbjct 238 PYRSDVLPVTAEWVNRLRNRGYAAFLSGAGPTCMVLGTTAVDEKILDDARE----AGIKV 293 Query 298 TELTVGEAVR 307 EL +GE V+ Sbjct 294 MELGIGEPVK 303 >gi|300781426|ref|ZP_07091280.1| homoserine kinase [Corynebacterium genitalium ATCC 33030] gi|300533133|gb|EFK54194.1| homoserine kinase [Corynebacterium genitalium ATCC 33030] Length=309 Score = 243 bits (620), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 148/302 (50%), Positives = 188/302 (63%), Gaps = 14/302 (4%) Query 7 LPSGLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTDSGLTVTVDGEGGDQVPLGP 66 L GL A V SSANLGPGFD++GLAL +YD + VE T SGL V + GEG D +P Sbjct 5 LEVGLRARVTVPGSSANLGPGFDTLGLALGIYDTVEVEVTSSGLEVEIFGEGADDLPRDG 64 Query 67 EHLVVRAVQHGLQAAGVSAAGLAVRCRNAIPHSRGLGSSAAAVVGGLAAVNGL---VVQT 123 HLVV+A++ L+AA V A GL V C N IP SRGLGSSA+A V G+ A N L V+ T Sbjct 65 SHLVVKAIRQALKAADVDAPGLKVTCTNNIPQSRGLGSSASAAVAGVVAANTLAGDVLDT 124 Query 124 DSSPSSDAELIQLASEFEGHPDNAAAAVLGGAVVSWTDHSGD---RPNYSAVSLRLHPDI 180 + E++Q++S FEGHPDNAAA+VLG AVVSWTD D P Y AV L +HPDI Sbjct 125 E-------EIVQISSSFEGHPDNAAASVLGQAVVSWTDIPVDGVSHPVYRAVQLPVHPDI 177 Query 181 RLFTAIPEQRSSTAETRVLLPAQVSHDDARFNVSRAALLVVALTERPDLLMAATEDLLHQ 240 + +P +ST R +LP+ V+H DARFNVSR A++ VA+ P+LL T D LHQ Sbjct 178 KATALVPSFHASTNAVRKVLPSHVTHTDARFNVSRTAVMTVAVQHHPELLWEGTRDRLHQ 237 Query 241 PQRAAAMTASAEYLRLLRRHNVAAALSGAGPSLIALSTDSELPTDAVEFGAAKGFAVTEL 300 P RA + +AE++ LR AA LSGAGP+ + L D P +E + G V +L Sbjct 238 PYRADVLPVTAEWVNRLRNRGYAAYLSGAGPTAMVLHRDPIDPK-IIESAKSDGLRVLDL 296 Query 301 TV 302 + Sbjct 297 EI 298 Lambda K H 0.315 0.129 0.361 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 549222890922 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40