BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1319c Length=535 Score E Sequences producing significant alignments: (Bits) Value gi|15608459|ref|NP_215835.1| adenylate cyclase [Mycobacterium tu... 1073 0.0 gi|253799635|ref|YP_003032636.1| adenylate cyclase [Mycobacteriu... 1071 0.0 gi|339631387|ref|YP_004723029.1| adenylate cyclase [Mycobacteriu... 1064 0.0 gi|15840772|ref|NP_335809.1| adenylate cyclase, putative [Mycoba... 1062 0.0 gi|148822541|ref|YP_001287295.1| adenylate cyclase [Mycobacteriu... 1060 0.0 gi|289745069|ref|ZP_06504447.1| adenylate cyclase [Mycobacterium... 1057 0.0 gi|326902942|gb|EGE49875.1| LOW QUALITY PROTEIN: adenylate cycla... 1057 0.0 gi|298524825|ref|ZP_07012234.1| conserved hypothetical protein [... 1047 0.0 gi|289757423|ref|ZP_06516801.1| adenylate cyclase [Mycobacterium... 1045 0.0 gi|289446915|ref|ZP_06436659.1| adenylate cyclase, putative [Myc... 1025 0.0 gi|306784048|ref|ZP_07422370.1| adenylate cyclase [Mycobacterium... 897 0.0 gi|289761474|ref|ZP_06520852.1| adenylate cyclase [Mycobacterium... 879 0.0 gi|306792738|ref|ZP_07431040.1| putative HAMP domain protein [My... 871 0.0 gi|306775497|ref|ZP_07413834.1| adenylate cyclase [Mycobacterium... 862 0.0 gi|306807215|ref|ZP_07443883.1| putative HAMP domain protein [My... 858 0.0 gi|307079317|ref|ZP_07488487.1| putative HAMP domain protein [My... 856 0.0 gi|306967412|ref|ZP_07480073.1| putative HAMP domain protein [My... 843 0.0 gi|306788409|ref|ZP_07426731.1| putative HAMP domain protein [My... 839 0.0 gi|306971605|ref|ZP_07484266.1| putative HAMP domain protein [My... 838 0.0 gi|254364216|ref|ZP_04980262.1| hypothetical adenylate cyclase (... 803 0.0 gi|298524824|ref|ZP_07012233.1| adenylate cyclase [Mycobacterium... 802 0.0 gi|15840771|ref|NP_335808.1| adenylate cyclase, putative [Mycoba... 799 0.0 gi|340626334|ref|YP_004744786.1| adenylate cyclase [Mycobacteriu... 798 0.0 gi|323720181|gb|EGB29283.1| adenylate cyclase [Mycobacterium tub... 783 0.0 gi|306803021|ref|ZP_07439689.1| putative HAMP domain protein [My... 781 0.0 gi|306797143|ref|ZP_07435445.1| putative HAMP domain protein [My... 775 0.0 gi|296170261|ref|ZP_06851852.1| adenylate cyclase [Mycobacterium... 775 0.0 gi|240169497|ref|ZP_04748156.1| adenylate cyclase [Mycobacterium... 759 0.0 gi|289573983|ref|ZP_06454210.1| conserved hypothetical protein [... 759 0.0 gi|306781596|ref|ZP_07419933.1| adenylate cyclase [Mycobacterium... 749 0.0 gi|183984049|ref|YP_001852340.1| adenylate cyclase [Mycobacteriu... 748 0.0 gi|342858019|ref|ZP_08714675.1| hypothetical protein MCOL_04055 ... 734 0.0 gi|41408538|ref|NP_961374.1| hypothetical protein MAP2440 [Mycob... 734 0.0 gi|118465998|ref|YP_880776.1| HAMP domain-containing protein [My... 733 0.0 gi|254821322|ref|ZP_05226323.1| hypothetical protein MintA_15392... 731 0.0 gi|340626333|ref|YP_004744785.1| putative adenylate cyclase [Myc... 730 0.0 gi|15608458|ref|NP_215834.1| adenylate cyclase [Mycobacterium tu... 728 0.0 gi|339631385|ref|YP_004723027.1| adenylate cyclase [Mycobacteriu... 728 0.0 gi|148822536|ref|YP_001287290.1| adenylate cyclase [Mycobacteriu... 726 0.0 gi|289442759|ref|ZP_06432503.1| adenylate cyclase [Mycobacterium... 713 0.0 gi|15840773|ref|NP_335810.1| adenylate cyclase, putative [Mycoba... 695 0.0 gi|289446916|ref|ZP_06436660.1| adenylate cyclase [Mycobacterium... 694 0.0 gi|15608460|ref|NP_215836.1| adenylate cyclase [Mycobacterium tu... 694 0.0 gi|339631388|ref|YP_004723030.1| adenylate cyclase [Mycobacteriu... 692 0.0 gi|340626336|ref|YP_004744788.1| putative adenylate cyclase [Myc... 692 0.0 gi|333989962|ref|YP_004522576.1| adenylate cyclase [Mycobacteriu... 691 0.0 gi|183984050|ref|YP_001852341.1| adenylate cyclase [Mycobacteriu... 688 0.0 gi|118473953|ref|YP_889179.1| adenylate cyclase, family protein ... 684 0.0 gi|120405263|ref|YP_955092.1| putative adenylate/guanylate cycla... 680 0.0 gi|145222924|ref|YP_001133602.1| putative adenylate/guanylate cy... 677 0.0 >gi|15608459|ref|NP_215835.1| adenylate cyclase [Mycobacterium tuberculosis H37Rv] gi|31792514|ref|NP_855007.1| adenylate cyclase [Mycobacterium bovis AF2122/97] gi|121637249|ref|YP_977472.1| putative adenylate cyclase [Mycobacterium bovis BCG str. Pasteur 1173P2] 13 more sequence titles Length=535 Score = 1073 bits (2775), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/535 (100%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 >gi|253799635|ref|YP_003032636.1| adenylate cyclase [Mycobacterium tuberculosis KZN 1435] gi|254231573|ref|ZP_04924900.1| hypothetical protein TBCG_01300 [Mycobacterium tuberculosis C] gi|289442760|ref|ZP_06432504.1| adenylate cyclase [Mycobacterium tuberculosis T46] 16 more sequence titles Length=535 Score = 1071 bits (2770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 534/535 (99%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIA+RLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 >gi|339631387|ref|YP_004723029.1| adenylate cyclase [Mycobacterium africanum GM041182] gi|340626335|ref|YP_004744787.1| putative adenylate cyclase [Mycobacterium canettii CIPT 140010059] gi|339330743|emb|CCC26414.1| putative adenylate cyclase (ATP pyrophosphate-lyase) [Mycobacterium africanum GM041182] gi|340004525|emb|CCC43668.1| putative adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium canettii CIPT 140010059] Length=534 Score = 1064 bits (2751), Expect = 0.0, Method: Compositional matrix adjust. Identities = 530/534 (99%), Positives = 532/534 (99%), Gaps = 0/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 534 >gi|15840772|ref|NP_335809.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|289573984|ref|ZP_06454211.1| adenylate cyclase [Mycobacterium tuberculosis K85] gi|13880965|gb|AAK45623.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|289538415|gb|EFD42993.1| adenylate cyclase [Mycobacterium tuberculosis K85] Length=558 Score = 1062 bits (2746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 530/534 (99%), Positives = 532/534 (99%), Gaps = 0/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 534 >gi|148822541|ref|YP_001287295.1| adenylate cyclase [Mycobacterium tuberculosis F11] gi|254364217|ref|ZP_04980263.1| hypothetical adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium tuberculosis str. Haarlem] gi|254550331|ref|ZP_05140778.1| adenylate cyclase, putative [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|134149731|gb|EBA41776.1| hypothetical adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium tuberculosis str. Haarlem] gi|148721068|gb|ABR05693.1| adenylate cyclase [Mycobacterium tuberculosis F11] Length=558 Score = 1060 bits (2741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/534 (99%), Positives = 532/534 (99%), Gaps = 0/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIA+RLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 534 >gi|289745069|ref|ZP_06504447.1| adenylate cyclase [Mycobacterium tuberculosis 02_1987] gi|294994875|ref|ZP_06800566.1| adenylate cyclase, putative [Mycobacterium tuberculosis 210] gi|289685597|gb|EFD53085.1| adenylate cyclase [Mycobacterium tuberculosis 02_1987] gi|339294301|gb|AEJ46412.1| adenylate cyclase, putative [Mycobacterium tuberculosis CCDC5079] gi|339297940|gb|AEJ50050.1| adenylate cyclase, putative [Mycobacterium tuberculosis CCDC5180] Length=558 Score = 1057 bits (2734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/534 (99%), Positives = 531/534 (99%), Gaps = 0/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLN FFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNWFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 534 >gi|326902942|gb|EGE49875.1| LOW QUALITY PROTEIN: adenylate cyclase [Mycobacterium tuberculosis W-148] Length=535 Score = 1057 bits (2733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 528/534 (99%), Positives = 530/534 (99%), Gaps = 0/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAI TYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIDTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLN FFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNWFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 534 >gi|298524825|ref|ZP_07012234.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298494619|gb|EFI29913.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=552 Score = 1047 bits (2708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/528 (99%), Positives = 526/528 (99%), Gaps = 0/528 (0%) Query 7 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI 66 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI Sbjct 1 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI 60 Query 67 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER 126 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER Sbjct 61 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER 120 Query 127 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT 186 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT Sbjct 121 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT 180 Query 187 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV 246 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV Sbjct 181 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV 240 Query 247 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF 306 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF Sbjct 241 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF 300 Query 307 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV 366 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV Sbjct 301 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV 360 Query 367 DIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP 426 DIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP Sbjct 361 DIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP 420 Query 427 EDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC 486 EDAALAAARAIADRLA+EMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC Sbjct 421 EDAALAAARAIADRLASEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC 480 Query 487 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 528 >gi|289757423|ref|ZP_06516801.1| adenylate cyclase [Mycobacterium tuberculosis T85] gi|289712987|gb|EFD76999.1| adenylate cyclase [Mycobacterium tuberculosis T85] Length=552 Score = 1045 bits (2703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/528 (99%), Positives = 525/528 (99%), Gaps = 0/528 (0%) Query 7 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI 66 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI Sbjct 1 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI 60 Query 67 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER 126 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER Sbjct 61 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER 120 Query 127 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT 186 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT Sbjct 121 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT 180 Query 187 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV 246 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV Sbjct 181 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV 240 Query 247 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF 306 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF Sbjct 241 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF 300 Query 307 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV 366 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV Sbjct 301 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV 360 Query 367 DIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP 426 DIVGSTQLVDNQPAAHVVKLLN FFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP Sbjct 361 DIVGSTQLVDNQPAAHVVKLLNWFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP 420 Query 427 EDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC 486 EDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC Sbjct 421 EDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC 480 Query 487 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 481 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 528 >gi|289446915|ref|ZP_06436659.1| adenylate cyclase, putative [Mycobacterium tuberculosis CPHL_A] gi|289419873|gb|EFD17074.1| adenylate cyclase, putative [Mycobacterium tuberculosis CPHL_A] Length=557 Score = 1025 bits (2649), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/534 (99%), Positives = 531/534 (99%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREV AAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREV-AAAERERPQLGGEDRH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 360 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN Sbjct 420 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRG+ QPT+LA P Sbjct 480 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASP 533 >gi|306784048|ref|ZP_07422370.1| adenylate cyclase [Mycobacterium tuberculosis SUMu003] gi|308331184|gb|EFP20035.1| adenylate cyclase [Mycobacterium tuberculosis SUMu003] Length=448 Score = 897 bits (2318), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/448 (100%), Positives = 448/448 (100%), Gaps = 0/448 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAARAIADRLANEMPEV 448 NRLDRPEDAALAAARAIADRLANEMPEV Sbjct 421 NRLDRPEDAALAAARAIADRLANEMPEV 448 >gi|289761474|ref|ZP_06520852.1| adenylate cyclase [Mycobacterium tuberculosis GM 1503] gi|289708980|gb|EFD72996.1| adenylate cyclase [Mycobacterium tuberculosis GM 1503] Length=446 Score = 879 bits (2271), Expect = 0.0, Method: Compositional matrix adjust. Identities = 441/442 (99%), Positives = 442/442 (100%), Gaps = 0/442 (0%) Query 94 VAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDI 153 VAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDI Sbjct 5 VAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDI 64 Query 154 GGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRF 213 GGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRF Sbjct 65 GGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRF 124 Query 214 APGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVM 273 APGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVM Sbjct 125 APGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVM 184 Query 274 WILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRD 333 WILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRD Sbjct 185 WILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRD 244 Query 334 LFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAI 393 LFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAI Sbjct 245 LFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAI 304 Query 394 VVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIG 453 VVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIA+RLANEMPEVQAGIG Sbjct 305 VVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIG 364 Query 454 VAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAH 513 VAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAH Sbjct 365 VAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAH 424 Query 514 WSLGETVTLRGHEQPTRLAVPT 535 WSLGETVTLRGHEQPTRLAVPT Sbjct 425 WSLGETVTLRGHEQPTRLAVPT 446 >gi|306792738|ref|ZP_07431040.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu005] gi|308338807|gb|EFP27658.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu005] Length=435 Score = 871 bits (2251), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/435 (100%), Positives = 435/435 (100%), Gaps = 0/435 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDAALAAAR 435 NRLDRPEDAALAAAR Sbjct 421 NRLDRPEDAALAAAR 435 >gi|306775497|ref|ZP_07413834.1| adenylate cyclase [Mycobacterium tuberculosis SUMu001] gi|308216000|gb|EFO75399.1| adenylate cyclase [Mycobacterium tuberculosis SUMu001] Length=429 Score = 862 bits (2227), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/429 (100%), Positives = 429/429 (100%), Gaps = 0/429 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPEDA 429 NRLDRPEDA Sbjct 421 NRLDRPEDA 429 >gi|306807215|ref|ZP_07443883.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu007] gi|308346359|gb|EFP35210.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu007] Length=427 Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/427 (100%), Positives = 427/427 (100%), Gaps = 0/427 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRPE 427 NRLDRPE Sbjct 421 NRLDRPE 427 >gi|307079317|ref|ZP_07488487.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu011] gi|308362813|gb|EFP51664.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu011] Length=430 Score = 856 bits (2211), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%), Gaps = 0/426 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 Query 421 NRLDRP 426 NRLDRP Sbjct 421 NRLDRP 426 >gi|306967412|ref|ZP_07480073.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu009] gi|308354930|gb|EFP43781.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu009] Length=431 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/431 (99%), Positives = 425/431 (99%), Gaps = 1/431 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF-AIVVNEVDRHHGLINKFAGDAALAIFGA 419 AAVVFVDIVGSTQLVDNQPAAHVVKL F +VVNEVDRHHGLINKFAGDAALAIFGA Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLPQPVFRRVVVNEVDRHHGLINKFAGDAALAIFGA 420 Query 420 PNRLDRPEDAA 430 PNRLDRPEDAA Sbjct 421 PNRLDRPEDAA 431 >gi|306788409|ref|ZP_07426731.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu004] gi|308335000|gb|EFP23851.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu004] Length=419 Score = 839 bits (2168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/419 (100%), Positives = 419/419 (100%), Gaps = 0/419 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGA 419 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGA Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGA 419 >gi|306971605|ref|ZP_07484266.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu010] gi|308358876|gb|EFP47727.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu010] Length=418 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/418 (100%), Positives = 418/418 (100%), Gaps = 0/418 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFG 418 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFG Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFG 418 >gi|254364216|ref|ZP_04980262.1| hypothetical adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium tuberculosis str. Haarlem] gi|134149730|gb|EBA41775.1| hypothetical adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium tuberculosis str. Haarlem] Length=532 Score = 803 bits (2075), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/532 (79%), Positives = 458/532 (87%), Gaps = 1/532 (0%) Query 4 KKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANL 63 KT QRL + LETMTRQ +L + PAYGSWLLG VSE P RR VRI+ I+T+ ++TANL Sbjct 2 SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANL 61 Query 64 TGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAI 123 GI +A+L+ AFP PSI +DAP W+TF PAY + +A+G+Y++ + + A++RWA Sbjct 62 VGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTL-AALRWAS 120 Query 124 EERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVL 183 EE PS+AD RNTLL P RVA LILW +G AL TLYGLANR+F+ ++FS CGVL Sbjct 121 EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL 180 Query 184 VATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYV 243 VAT CY+ TEFALRPVAA+ALEAG PP RFA GI+GRTM VW L SGVP+ GIA + Sbjct 181 VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE 240 Query 244 LLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDL 303 +++ N T+ Q A VLI+S TLI GFL+MWILAWLTAAPVRVVRAALKRVEQGDLRGDL Sbjct 241 MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWILAWLTAAPVRVVRAALKRVEQGDLRGDL 300 Query 304 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 363 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV Sbjct 301 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 360 Query 364 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 423 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL Sbjct 361 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 420 Query 424 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 483 DRPEDAALAAARAIA+RLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA Sbjct 421 DRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 480 Query 484 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 532 >gi|298524824|ref|ZP_07012233.1| adenylate cyclase [Mycobacterium tuberculosis 94_M4241A] gi|298494618|gb|EFI29912.1| adenylate cyclase [Mycobacterium tuberculosis 94_M4241A] Length=532 Score = 802 bits (2072), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/532 (79%), Positives = 458/532 (87%), Gaps = 1/532 (0%) Query 4 KKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANL 63 KT QRL + LETMTRQ +L + PAYGSWLLG VSE P RR VRI+ I+T+ ++TANL Sbjct 2 SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANL 61 Query 64 TGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAI 123 GI +A+L+ AFP PSI +DAP W+TF PAY + +A+G+Y++ + + A++RWA Sbjct 62 VGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTL-AALRWAS 120 Query 124 EERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVL 183 EE PS+AD RNTLL P RVA LILW +G AL TLYGLANR+F+ ++FS CGVL Sbjct 121 EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL 180 Query 184 VATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYV 243 VAT CY+ TEFALRPVAA+ALEAG PP RFA GI+GRTM VW L SGVP+ GIA + Sbjct 181 VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE 240 Query 244 LLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDL 303 +++ N T+ Q A VLI+S TLI GFL+MWI++WLTAAPVRVVRAALKRVEQGDLRGDL Sbjct 241 MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDL 300 Query 304 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 363 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV Sbjct 301 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 360 Query 364 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 423 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL Sbjct 361 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 420 Query 424 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 483 DRPEDAALAAARAIA+RLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA Sbjct 421 DRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 480 Query 484 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 532 >gi|15840771|ref|NP_335808.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|289446914|ref|ZP_06436658.1| adenylate cyclase, putative [Mycobacterium tuberculosis CPHL_A] gi|289745068|ref|ZP_06504446.1| adenylate cyclase [Mycobacterium tuberculosis 02_1987] 10 more sequence titles Length=532 Score = 799 bits (2064), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/532 (79%), Positives = 458/532 (87%), Gaps = 1/532 (0%) Query 4 KKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANL 63 KT QRL + LETMTRQ +L + PAYGSWLLG VSE P RR VRI+ I+T+ ++TANL Sbjct 2 SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANL 61 Query 64 TGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAI 123 GI +A+L+ AFP PSI +DAP W+TF PAY + +A+G+Y++ + + A++RWA Sbjct 62 VGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTL-AALRWAS 120 Query 124 EERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVL 183 EE PS+AD RNTLL P RVA LILW +G AL TLYGLANR+F+ ++FS CGVL Sbjct 121 EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL 180 Query 184 VATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYV 243 VAT CY+ TEFALRPVAA+ALEAG PP RFA GI+GRTM VW L SGVP+ GIA + Sbjct 181 VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE 240 Query 244 LLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDL 303 +++ N T+ Q A VLI+S TLI GFL+MWI++WLTAAPVRVVRAALKRVEQGDLRGDL Sbjct 241 MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDL 300 Query 304 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 363 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV Sbjct 301 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 360 Query 364 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 423 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL Sbjct 361 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 420 Query 424 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 483 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA Sbjct 421 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 480 Query 484 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 532 >gi|340626334|ref|YP_004744786.1| adenylate cyclase [Mycobacterium canettii CIPT 140010059] gi|340004524|emb|CCC43667.1| adenylate cyclase, putative [Mycobacterium canettii CIPT 140010059] Length=532 Score = 798 bits (2060), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/532 (79%), Positives = 457/532 (86%), Gaps = 1/532 (0%) Query 4 KKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANL 63 KT QRL + LETMTRQ +L + PAYGSWLLG VSE P RR VRI+ I+T+ ++TANL Sbjct 2 SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANL 61 Query 64 TGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAI 123 GI +A+L+ AFP PSI +DAP W+TF PAY + +A+G+Y++ + + A++RWA Sbjct 62 VGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTL-AALRWAS 120 Query 124 EERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVL 183 EE PS+AD RNTLL P RVA LILW +G AL TLYGLANR+F+ ++FS CGVL Sbjct 121 EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL 180 Query 184 VATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYV 243 VAT CY+ TEFALRPVAA+ALEAG PP RFA GI+GRTM VW L SGVP+ GIA + Sbjct 181 VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE 240 Query 244 LLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDL 303 +++ N T+ Q A VLI+S TLI GFL+MWI++WLTAAPVRVVRAALKRVEQGDLRGDL Sbjct 241 MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDL 300 Query 304 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 363 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV Sbjct 301 VVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAV 360 Query 364 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 423 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL Sbjct 361 VFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRL 420 Query 424 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 483 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA Sbjct 421 DRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAA 480 Query 484 RLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT 535 RLCELAKSHPARLLASSDTLH ASETERAHWSLGETVTLRGHEQPTRLAVPT Sbjct 481 RLCELAKSHPARLLASSDTLHGASETERAHWSLGETVTLRGHEQPTRLAVPT 532 >gi|323720181|gb|EGB29283.1| adenylate cyclase [Mycobacterium tuberculosis CDC1551A] Length=403 Score = 783 bits (2022), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/390 (100%), Positives = 390/390 (100%), Gaps = 0/390 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRF 390 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRF Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRF 390 >gi|306803021|ref|ZP_07439689.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu008] gi|308350283|gb|EFP39134.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu008] Length=442 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/391 (100%), Positives = 391/391 (100%), Gaps = 0/391 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF 391 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF Sbjct 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF 391 >gi|306797143|ref|ZP_07435445.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu006] gi|308342478|gb|EFP31329.1| putative HAMP domain protein [Mycobacterium tuberculosis SUMu006] Length=414 Score = 775 bits (2002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/391 (99%), Positives = 390/391 (99%), Gaps = 1/391 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREV AAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREV-AAAERERPQLGGEDRH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF 391 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF Sbjct 360 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFF 390 >gi|296170261|ref|ZP_06851852.1| adenylate cyclase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894984|gb|EFG74703.1| adenylate cyclase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=544 Score = 775 bits (2001), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/534 (72%), Positives = 449/534 (85%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A +++A+R+G+ LET+TRQ G+LPETPAYGS LLGRV+ES RR +RI+ I+TV ++ Sbjct 1 MSANQSLAKRIGRVLETVTRQSGRLPETPAYGSLLLGRVTESQQRRRIRIQVILTVLVLG 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GIVVALL+VT A P PS++ DAPWW+TF +PAY LALA+GTYWIT R V A +R Sbjct 61 ANLIGIVVALLLVTVAIPQPSVFDDAPWWITFAASPAYIALALAVGTYWITRRTVLA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAP++ D RNT L P+R+A LILW +G +L TLYGL N +F+ L +V IC Sbjct 120 WAIEERAPTEEDERNTFLAPWRIARFDLILWGVGAVVLTTLYGLVNTLFIPRFLIAVGIC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 G+LVAT YL EFALRP AA+ALEAG PPRRFA GIMGRTM VW LGSG+PV GIA A Sbjct 180 GILVATGSYLLAEFALRPAAAQALEAGPPPRRFASGIMGRTMVVWFLGSGLPVLGIAFLA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 + L+ NLTETQ A VL++SI T+ FG L+MWILAWLTA PVRVVRAAL+RVE+GDLR Sbjct 240 GFQALMRNLTETQFAVGVLMVSIATVTFGCLLMWILAWLTATPVRVVRAALRRVERGDLR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMV+GLRERERVRDLFGRHVGREVA AAERE+P+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAEREKPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGST+LV ++PAA +V+LLNRFFAIVV EVDRH GL+NKF GDA LA+FGAP Sbjct 360 VAVVFIDIVGSTKLVTSRPAAEIVQLLNRFFAIVVEEVDRHCGLVNKFEGDATLAVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLDRPE+ ALAAAR+IA RL +E+ E QAGIGVAAGQ+VAGNVGA++RFEYTV+G PVN Sbjct 420 NRLDRPEEQALAAARSIAGRLDSEIAECQAGIGVAAGQVVAGNVGARERFEYTVIGGPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +A+RLCELAKSHP RLLA++D L AS+TERA WSLG+TVTLRGHE+PTRLA P Sbjct 480 EASRLCELAKSHPGRLLATADALEGASDTERARWSLGDTVTLRGHERPTRLASP 533 >gi|240169497|ref|ZP_04748156.1| adenylate cyclase [Mycobacterium kansasii ATCC 12478] Length=541 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/534 (71%), Positives = 448/534 (84%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A+++MAQRLG+ LET+TRQ G+L ETPAYGSWLLGRVSE RR +RI+ I+TV ++ Sbjct 1 MVAEESMAQRLGRVLETVTRQSGRLSETPAYGSWLLGRVSEDQRRRRIRIQVILTVMVVA 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 AN+ GI V++L+VT A P PS+++DAP WV+F V PAY +ALA+G YWIT R V A +R Sbjct 61 ANVIGIAVSILLVTVAIPEPSVFSDAPLWVSFAVVPAYIVVALALGAYWITRRTVIA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER P+ D RNT L P+RVA V LILW +G ALL TLYG+AN +F+ LF+V+ C Sbjct 120 WAIEERPPTHDDERNTFLTPWRVAIVDLILWGVGAALLTTLYGMANTMFIPRFLFAVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 G+LVAT YL TEFALRPVAA+ALEAG PPRR A GIMGRTM VW LGSGVP+ GIA A Sbjct 180 GLLVATGSYLLTEFALRPVAAQALEAGPPPRRLASGIMGRTMMVWLLGSGVPIVGIALIA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ + + NLT TQ A VLI+S+ TL+FGF++MWILAWLTA PVRVVRAAL+RVE+GDLR Sbjct 240 IFQIGMRNLTATQFAVGVLIVSMATLVFGFVLMWILAWLTATPVRVVRAALQRVERGDLR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNAMVHGLRERERVRDLFGRHVGREVALAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGST+LV +QP A VV+LLNRFFAIVV EVDRH+GL+NKF GDA+LAIFGAP Sbjct 360 VAVVFLDIVGSTKLVTSQPPAEVVQLLNRFFAIVVEEVDRHYGLVNKFEGDASLAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 N LD+PED ALA AR +A RLA EM E QAGIGVA+GQ+VAGNVG+K+RFEYTV+G+PVN Sbjct 420 NHLDQPEDQALACARTLAQRLAEEMRECQAGIGVASGQVVAGNVGSKERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCE AKS P +LLAS+ T+ AASE+ERAHW+LG V LRGH+QPTRLA P Sbjct 480 EAARLCERAKSRPGKLLASAQTVEAASESERAHWTLGRHVKLRGHKQPTRLASP 533 >gi|289573983|ref|ZP_06454210.1| conserved hypothetical protein [Mycobacterium tuberculosis K85] gi|289538414|gb|EFD42992.1| conserved hypothetical protein [Mycobacterium tuberculosis K85] Length=496 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/497 (80%), Positives = 433/497 (88%), Gaps = 1/497 (0%) Query 39 VSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAY 98 +SE P RR VRI+ I+T+ ++TANL GI +A+L+ AFP PSI +DAP W+TF PAY Sbjct 1 MSERPLRRRVRIQIILTIALITANLVGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAY 60 Query 99 ATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALL 158 + +A+G+Y++ + + A++RWA EE PS+AD RNTLL P RVA LILW +G AL Sbjct 61 TVIGMALGSYYVKVQTL-AALRWASEEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALF 119 Query 159 ATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIM 218 TLYGLANR+F+ ++FS CGVLVAT CY+ TEFALRPVAA+ALEAG PP RFA GI+ Sbjct 120 TTLYGLANRLFIPQVMFSTLFCGVLVATACYMLTEFALRPVAAQALEAGLPPGRFALGII 179 Query 219 GRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAW 278 GRTM VW L SGVP+ GIA + +++ N T+ Q A VLI+S TLI GFL+MWI++W Sbjct 180 GRTMVVWLLSSGVPLFGIALLGILEMVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSW 239 Query 279 LTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRH 338 LTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRH Sbjct 240 LTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRH 299 Query 339 VGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEV 398 VGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEV Sbjct 300 VGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEV 359 Query 399 DRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQ 458 DRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQ Sbjct 360 DRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQ 419 Query 459 IVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGE 518 IVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGE Sbjct 420 IVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGE 479 Query 519 TVTLRGHEQPTRLAVPT 535 TVTLRGHEQPTRLAVPT Sbjct 480 TVTLRGHEQPTRLAVPT 496 >gi|306781596|ref|ZP_07419933.1| adenylate cyclase [Mycobacterium tuberculosis SUMu002] gi|308325649|gb|EFP14500.1| adenylate cyclase [Mycobacterium tuberculosis SUMu002] Length=375 Score = 749 bits (1933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/375 (100%), Positives = 375/375 (100%), Gaps = 0/375 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT Sbjct 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR Sbjct 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC Sbjct 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA Sbjct 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR Sbjct 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH Sbjct 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 Query 361 AAVVFVDIVGSTQLV 375 AAVVFVDIVGSTQLV Sbjct 361 AAVVFVDIVGSTQLV 375 >gi|183984049|ref|YP_001852340.1| adenylate cyclase [Mycobacterium marinum M] gi|183177375|gb|ACC42485.1| adenylate cyclase [Mycobacterium marinum M] Length=550 Score = 748 bits (1930), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/528 (72%), Positives = 439/528 (84%), Gaps = 1/528 (0%) Query 7 MAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGI 66 +AQRLG+ LE +TRQ G+LPETPAYGSWLLGRVSES RR +RI+ I+TV ++ ANL GI Sbjct 23 VAQRLGRVLERVTRQSGRLPETPAYGSWLLGRVSESQQRRRIRIQTILTVMVVVANLLGI 82 Query 67 VVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEER 126 V++L+VT A P PS++T+APWW+TF V P+Y +ALA+GTYWIT R V A +RWAIEER Sbjct 83 AVSILLVTVAIPSPSVFTEAPWWITFVVVPSYIVVALALGTYWITRRTVLA-LRWAIEER 141 Query 127 APSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVAT 186 P+ D RNT L +RVA V LILW G LL TLYG+AN +F+ LF+VT CGVLVAT Sbjct 142 QPTPEDERNTFLAAWRVAVVDLILWGSGAVLLTTLYGMANTMFIPRFLFAVTFCGVLVAT 201 Query 187 NCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLV 246 YL TEFALRPVAA+AL AG PPRR + GIMGRTM VW LGSGVPV GIA A++ + + Sbjct 202 GSYLLTEFALRPVAAQALAAGPPPRRLSSGIMGRTMMVWLLGSGVPVVGIALVAIFQIAL 261 Query 247 HNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVF 306 NL+ETQ A VLI+S+ TLIFGF++MWI++WLTA PVRVVRAAL RV GDLRGDLVVF Sbjct 262 RNLSETQFAVGVLIVSMATLIFGFILMWIMSWLTATPVRVVRAALNRVANGDLRGDLVVF 321 Query 307 DGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFV 366 DGTELGELQRGFN MV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH AVVF+ Sbjct 322 DGTELGELQRGFNTMVDGLRERERVRDLFGRHVGREVAIAAERERPKLGGEERHVAVVFI 381 Query 367 DIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRP 426 DIVGST+LV +QP A VV LLNRFFA+VV+EVDRH GL+NKF GDA+LAIFGAPN L+RP Sbjct 382 DIVGSTKLVTSQPPADVVALLNRFFAVVVDEVDRHRGLVNKFEGDASLAIFGAPNHLERP 441 Query 427 EDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLC 486 ED ALAAAR IA RLA+E+PE QAGIGVAAGQ+VAGNVG+K+RFEYTV+G+PVN+AARLC Sbjct 442 EDQALAAARTIAARLASEVPECQAGIGVAAGQVVAGNVGSKERFEYTVIGEPVNEAARLC 501 Query 487 ELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 ELAK HP RLLAS L AS ERA WS+G+TVTLRGH+QPTRLA P Sbjct 502 ELAKDHPGRLLASGAALDGASHDERARWSVGKTVTLRGHDQPTRLAAP 549 >gi|342858019|ref|ZP_08714675.1| hypothetical protein MCOL_04055 [Mycobacterium colombiense CECT 3035] gi|342135352|gb|EGT88518.1| hypothetical protein MCOL_04055 [Mycobacterium colombiense CECT 3035] Length=539 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/534 (70%), Positives = 431/534 (81%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M +++AQR+G+ LE +TRQ G+LPETPAYGS LLGRVSES RR +RI+ I+TV ++ Sbjct 1 MSPNQSVAQRIGRVLERVTRQSGRLPETPAYGSLLLGRVSESQGRRRIRIQIIMTVLVLG 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI L++V A PVPSI+ DAP W+TFGVAPAY LAL +GT WIT R V A +R Sbjct 61 ANLLGIGAGLILVIVAIPVPSIFDDAPAWLTFGVAPAYIVLALTVGTVWITRRTVLA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER P+ D RNT + P+R+A V L+LW G L LYGL N +F+ L V+ C Sbjct 120 WAIEERTPTPEDERNTFIAPWRIALVDLVLWGTGALLYTVLYGLVNTMFIPRFLVGVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL E +LRPVAA+ALEAG PPRR A GIMGRTM VW LGSGVP+ GIA Sbjct 180 GVLVATGSYLLAELSLRPVAAQALEAGPPPRRLAAGIMGRTMMVWFLGSGVPIIGIALLT 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 L+ + + NLT+TQ A VLI+S LIFG ++MWILAWLTA PVRVVRAAL+RVE+GDLR Sbjct 240 LFEIWLRNLTQTQFAVGVLIVSSAALIFGCMLMWILAWLTATPVRVVRAALQRVEEGDLR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMV+GLRERERVRDLFGRHVGREVA AAERE P+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAEREMPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV N+P A VV +LN+FFAIVV EVDRHHGL+NKF GDA+LAIFGAP Sbjct 360 VAVVFIDIVGSTQLVTNRPPAEVVSVLNQFFAIVVEEVDRHHGLVNKFEGDASLAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRLD PED ALAAAR I RLANEM E+ AGIGVAAGQ VAGNVGA++RFEYTV+G+PVN Sbjct 420 NRLDSPEDEALAAARCITGRLANEMSELSAGIGVAAGQAVAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKSH +RLLA++D + ASE ER WSLG+TVTLRGHE+PTRLA P Sbjct 480 EAARLCELAKSHSSRLLATADAVERASENERERWSLGDTVTLRGHERPTRLASP 533 >gi|41408538|ref|NP_961374.1| hypothetical protein MAP2440 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396896|gb|AAS04757.1| hypothetical protein MAP_2440 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460972|gb|EGO39853.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis S397] Length=544 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/534 (72%), Positives = 437/534 (82%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A ++ AQR+G+ LE +TRQ G+LPETPAYGS LLGRV+ES RR +RI+ I+TV ++ Sbjct 1 MSATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLG 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI AL++V A P PS++ DAP W+TFGV PAY ALA+GTYWIT R V A +R Sbjct 61 ANLIGIGAALILVIVAIPAPSVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER P+ D RNT L P+R+A V L+LW G LL LYGL + +F+ LF V+ C Sbjct 120 WAIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVLYGLVDTMFIPRFLFGVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT CYL EFALRPVAA+ALEAG PPRR GIMGRTMTVW LGSGVPV GIA A Sbjct 180 GVLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 L+ + + NLTET+ A VLI+S LIFG L+MWILAWLTA PVRVVRAALKRVE+GDLR Sbjct 240 LFEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV +P A VV +LN+FF IVV EVDRH GL+NKF GDA LAIFGAP Sbjct 360 VAVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRHCGLVNKFEGDATLAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 N LD PEDAAL AARAIADRLANEMP+ +AGIGVAAGQ+VAGNVGA++RFEYTV+G+PVN Sbjct 420 NHLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKSH +RLLA+ D + ASE ERA WSLG+TVTLRGHE+PTRLA P Sbjct 480 EAARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASP 533 >gi|118465998|ref|YP_880776.1| HAMP domain-containing protein [Mycobacterium avium 104] gi|254774360|ref|ZP_05215876.1| HAMP domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118167285|gb|ABK68182.1| hamp domain protein [Mycobacterium avium 104] Length=544 Score = 733 bits (1893), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/534 (72%), Positives = 436/534 (82%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A ++ AQR+G+ LE +TRQ G+LPETPAYGS LLGRV+ES RR +RI+ I+TV ++ Sbjct 1 MSATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLG 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI AL++V A P PS++ DAP W+TFGV PAY ALA+GTYWIT R V A +R Sbjct 61 ANLIGIGAALILVIVAIPAPSVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER P+ D RNT L P+R+A V L+LW G LL LYGL + +F+ LF V+ C Sbjct 120 WAIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVLYGLVDTMFIPRFLFGVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT CYL EFALRPVAA+ALEAG PPRR GIMGRTMTVW LGSGVPV GIA A Sbjct 180 GVLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 L+ + + NLTET+ A VLI+S LIFG L+MWILAWLTA PVRVVRAALKRVE+GDLR Sbjct 240 LFEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFNAMV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV +P A VV +LN+FF IVV EVDRH GL+NKF GDA LAIFGAP Sbjct 360 VAVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRHCGLVNKFEGDATLAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 N LD PEDAAL AARAIADRLANEMP+ +AGIGVAAGQ+VAGNVGA++RFEYTV+G+PVN Sbjct 420 NHLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKSH RLLA+ D + ASE ERA WSLG+TVTLRGHE+PTRLA P Sbjct 480 EAARLCELAKSHSGRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASP 533 >gi|254821322|ref|ZP_05226323.1| hypothetical protein MintA_15392 [Mycobacterium intracellulare ATCC 13950] Length=528 Score = 731 bits (1886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/518 (73%), Positives = 428/518 (83%), Gaps = 1/518 (0%) Query 15 LETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVT 74 LE +TRQ G+LPETPAYGS LLGRVSES RR VRI+ I+TV ++ ANL GI VAL +VT Sbjct 2 LERVTRQSGRLPETPAYGSLLLGRVSESQGRRRVRIQIIMTVLVLGANLIGIAVALFLVT 61 Query 75 FAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGR 134 A PVPS++ DAP W+TFG +PAY A A GTYWIT R V A +RWAIEER P+ D R Sbjct 62 VAIPVPSVFDDAPAWITFGASPAYIVAASAWGTYWITRRTVIA-LRWAIEEREPTPEDER 120 Query 135 NTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEF 194 NT + P+R+A V L+LW +G LL TLYG+ N +F+ L V+ GV+VAT YL EF Sbjct 121 NTFVAPWRIALVDLVLWGVGTILLTTLYGMVNTLFIPRFLLVVSFGGVVVATASYLLAEF 180 Query 195 ALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQL 254 ALRPVAA+ALEAG PPRRFA GIMGRTM VW LGS VPV GI AL+ L++ NLT+TQ Sbjct 181 ALRPVAAQALEAGPPPRRFAAGIMGRTMVVWFLGSAVPVIGIMMLALFELVLRNLTQTQF 240 Query 255 ASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGEL 314 A AVLI+S+ LIFG ++MWILAWLTA PVRVVRAAL RVE+GDLRGDLVVFDGTELGEL Sbjct 241 AVAVLIVSMAPLIFGCVLMWILAWLTATPVRVVRAALARVERGDLRGDLVVFDGTELGEL 300 Query 315 QRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQL 374 QRGFN MV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH AVVF+DIVGSTQL Sbjct 301 QRGFNTMVDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHVAVVFIDIVGSTQL 360 Query 375 VDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAA 434 V +QP A VV +LNRFFAIVV EVDR+ GL+NKF GDA LAIFGAPNRLD PEDAALAAA Sbjct 361 VTSQPPAEVVAVLNRFFAIVVEEVDRYCGLVNKFEGDATLAIFGAPNRLDSPEDAALAAA 420 Query 435 RAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPA 494 R IA+RLA+EM +++AGIGVAAGQ+VAGNVGAK+RFEYTV+G+PVN+AARLCELAKSH Sbjct 421 RCIAERLADEMSDLEAGIGVAAGQVVAGNVGAKERFEYTVIGEPVNEAARLCELAKSHTN 480 Query 495 RLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLA 532 RLLA++D + ASE ERA WSLGETVTLRGHE+PTRLA Sbjct 481 RLLATADAIEGASEDERARWSLGETVTLRGHERPTRLA 518 >gi|340626333|ref|YP_004744785.1| putative adenylate cyclase [Mycobacterium canettii CIPT 140010059] gi|340004523|emb|CCC43666.1| putative adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium canettii CIPT 140010059] Length=541 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/534 (72%), Positives = 442/534 (83%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M AKK+ AQRLG+ LET+TRQ G+LPETPAYGSWLLGRVSES RR VRI+ ++T ++T Sbjct 1 MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI VALL+VT A P PSI D P W+TFGV P Y LALA+G+Y +T + V+A +R Sbjct 61 ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALAVGSYALTRQTVQA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIE R P++ D R T L P+RVA HL+ W +G ALL TLYGL N F+ LF+V+ C Sbjct 120 WAIEGRKPTREDERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRP AA+ALEAG PPRR APGI+GRTM VW LGSGVPV GIA A Sbjct 180 GVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ +++ NLT Q A+ VLI+S+ TL+FGF++MWILAWLTA PVRVVRAAL+RVE+G+LR Sbjct 240 MFEMVLLNLTRMQFATGVLIISMVTLVFGFILMWILAWLTATPVRVVRAALRRVERGELR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFNAMV GLRERERVRDLFGRHVGREVAAAAERER +LGGE+RH Sbjct 300 TNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV ++P A VVKLLN+FFAIVV+EVDRHHGL+NKF GDA+L IFGAP Sbjct 360 VAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PED ALAAARAIADRL NEMPE QAGIGVAAGQ++AGNVGA++RFEYTV+G+PVN Sbjct 420 NRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS P +LLAS+ + AASE ERA WSLG V LRGH+QP RLA P Sbjct 480 EAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKP 533 >gi|15608458|ref|NP_215834.1| adenylate cyclase [Mycobacterium tuberculosis H37Rv] gi|15840770|ref|NP_335807.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|31792513|ref|NP_855006.1| adenylate cyclase [Mycobacterium bovis AF2122/97] 60 more sequence titles Length=541 Score = 728 bits (1879), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/534 (71%), Positives = 442/534 (83%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M AKK+ AQRLG+ LET+TRQ G+LPETPAYGSWLLGRVSES RR VRI+ ++T ++T Sbjct 1 MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI VALL+VT A P PSI D P W+TFGV P Y LALA+G+Y +T + V+A +R Sbjct 61 ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIE R P++ + R T L P+RVA HL+ W +G ALL TLYGL N F+ LF+V+ C Sbjct 120 WAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRP AA+ALEAG PPRR APGI+GRTM VW LGSGVPV GIA A Sbjct 180 GVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ +++ NLT Q A+ VLI+S+ TL+FGF++MWILAWLTA PVRVVRAAL+RVE+G+LR Sbjct 240 MFEMVLLNLTRMQFATGVLIISMVTLVFGFILMWILAWLTATPVRVVRAALRRVERGELR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFNAMV GLRERERVRDLFGRHVGREVAAAAERER +LGGE+RH Sbjct 300 TNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV ++P A VVKLLN+FFAIVV+EVDRHHGL+NKF GDA+L IFGAP Sbjct 360 VAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PED ALAAARAIADRL NEMPE QAGIGVAAGQ++AGNVGA++RFEYTV+G+PVN Sbjct 420 NRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS P +LLAS+ + AASE ERA WSLG V LRGH+QP RLA P Sbjct 480 EAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKP 533 >gi|339631385|ref|YP_004723027.1| adenylate cyclase [Mycobacterium africanum GM041182] gi|339330741|emb|CCC26412.1| putative adenylate cyclase (ATP pyrophosphate-lyase) [Mycobacterium africanum GM041182] Length=541 Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/534 (71%), Positives = 442/534 (83%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M AKK+ AQRLG+ LET+TRQ G+LPETPAYGSWLLGRVSES RR VRI+ ++T ++T Sbjct 1 MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI VALL+VT A P PSI D P W+TFGV P Y LALA+G+Y +T + V+A +R Sbjct 61 ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIE R P++ + R T L P+RVA HL+ W +G ALL TLYGL N F+ LF+V+ C Sbjct 120 WAIEGRKPAREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRP AA+ALEAG PPRR APGI+GRTM VW LGSGVPV GIA A Sbjct 180 GVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ +++ NLT Q A+ VLI+S+ TL+FGF++MWILAWLTA PVRVVRAAL+RVE+G+LR Sbjct 240 MFEMVLLNLTRMQFATGVLIISMVTLVFGFILMWILAWLTATPVRVVRAALRRVERGELR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFNAMV GLRERERVRDLFGRHVGREVAAAAERER +LGGE+RH Sbjct 300 TNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV ++P A VVKLLN+FFAIVV+EVDRHHGL+NKF GDA+L IFGAP Sbjct 360 VAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PED ALAAARAIADRL NEMPE QAGIGVAAGQ++AGNVGA++RFEYTV+G+PVN Sbjct 420 NRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS P +LLAS+ + AASE ERA WSLG V LRGH+QP RLA P Sbjct 480 EAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKP 533 >gi|148822536|ref|YP_001287290.1| adenylate cyclase [Mycobacterium tuberculosis F11] gi|253799636|ref|YP_003032637.1| adenylate cyclase [Mycobacterium tuberculosis KZN 1435] gi|254550326|ref|ZP_05140773.1| adenylate cyclase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] 11 more sequence titles Length=541 Score = 726 bits (1873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/534 (71%), Positives = 441/534 (83%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M AKK+ AQRLG+ LET+TRQ G+LPETPAYGSWLLGRVSES RR VRI+ ++T ++T Sbjct 1 MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI VALL+VT A P PSI D P W+TFGV P Y LALA+G+Y +T + V+A +R Sbjct 61 ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIE R P++ + R T L P+RVA HL+ W +G ALL TLYGL N F+ LF+V+ C Sbjct 120 WAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFIPRFLFAVSFC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRP AA+ALEAG PPRR APGI+GRTM VW LGSGVPV GIA A Sbjct 180 GVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ +++ NLT Q A+ VLI+S+ TL+ GF++MWILAWLTA PVRVVRAAL+RVE+G+LR Sbjct 240 MFEMVLLNLTRMQFATGVLIISMVTLVLGFILMWILAWLTATPVRVVRAALRRVERGELR 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFNAMV GLRERERVRDLFGRHVGREVAAAAERER +LGGE+RH Sbjct 300 TNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV ++P A VVKLLN+FFAIVV+EVDRHHGL+NKF GDA+L IFGAP Sbjct 360 VAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PED ALAAARAIADRL NEMPE QAGIGVAAGQ++AGNVGA++RFEYTV+G+PVN Sbjct 420 NRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS P +LLAS+ + AASE ERA WSLG V LRGH+QP RLA P Sbjct 480 EAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKP 533 >gi|289442759|ref|ZP_06432503.1| adenylate cyclase [Mycobacterium tuberculosis T46] gi|289415678|gb|EFD12918.1| adenylate cyclase [Mycobacterium tuberculosis T46] Length=540 Score = 713 bits (1841), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/534 (71%), Positives = 438/534 (83%), Gaps = 2/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M AKK+ AQRLG+ LET+TRQ G+LPETPAYGSWLLGRVSES RR VRI+ ++T ++T Sbjct 1 MSAKKSTAQRLGRVLETVTRQSGRLPETPAYGSWLLGRVSESQRRRRVRIQVMLTALVVT 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI VALL+VT A P PSI D P W+TFGV P Y LALA+G+Y +T + V+A +R Sbjct 61 ANLLGIGVALLLVTIAIPEPSIVRDTPRWLTFGVVPGYVLLALALGSYALTRQTVQA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIE R P++ + R T L P+RVA HL+ W +G ALL TLYGL N F+ I S Sbjct 120 WAIEGRKPTREEERRTFLAPWRVAVGHLMFWGVGTALLTTLYGLINNAFI-IDRCSQQRG 178 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRP AA+ALEAG PPRR APGI+GRTM VW LGSGVPV GIA A Sbjct 179 GVLVATATYLHTEFALRPFAAQALEAGPPPRRLAPGILGRTMVVWLLGSGVPVVGIALMA 238 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ +++ NLT Q A+ VLI+S+ TL+FGF++MWILAWLTA PVRVVRAAL+RVE+G+LR Sbjct 239 MFEMVLLNLTRMQFATGVLIISMVTLVFGFILMWILAWLTATPVRVVRAALRRVERGELR 298 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFNAMV GLRERERVRDLFGRHVGREVAAAAERER +LGGE+RH Sbjct 299 TNLVVFDGTELGELQRGFNAMVAGLRERERVRDLFGRHVGREVAAAAERERSKLGGEERH 358 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGSTQLV ++P A VVKLLN+FFAIVV+EVDRHHGL+NKF GDA+L IFGAP Sbjct 359 VAVVFIDIVGSTQLVTSRPPADVVKLLNKFFAIVVDEVDRHHGLVNKFEGDASLTIFGAP 418 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PED ALAAARAIADRL NEMPE QAGIGVAAGQ++AGNVGA++RFEYTV+G+PVN Sbjct 419 NRLPCPEDKALAAARAIADRLVNEMPECQAGIGVAAGQVIAGNVGARERFEYTVIGEPVN 478 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS P +LLAS+ + AASE ERA WSLG V LRGH+QP RLA P Sbjct 479 EAARLCELAKSRPGKLLASAQAVDAASEEERARWSLGRHVKLRGHDQPVRLAKP 532 >gi|15840773|ref|NP_335810.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|31792515|ref|NP_855008.1| adenylate cyclase [Mycobacterium bovis AF2122/97] gi|121637250|ref|YP_977473.1| putative adenylate cyclase [Mycobacterium bovis BCG str. Pasteur 1173P2] 64 more sequence titles Length=567 Score = 695 bits (1794), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/534 (67%), Positives = 419/534 (79%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MP++K + L A+ET++ + G+ PETPAYGSWLLGRVSESP R VRI+ ++TV I+ Sbjct 1 MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ G++V +++T AFP PS+ DAP WV+FG+ P Y LA +GTYW+T + RA +R Sbjct 61 TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER PS + R+ L+P RVA L LW AL +YGLANR+F+ LFS+ + Sbjct 120 WAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVI 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GV+ AT+CYL TEFALRP+AA+ALE G PR GI+GRTM VW L SGVP G+A TA Sbjct 180 GVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L+ Q VLIL LIFGF++MWILAWLTA PVRVVR AL RVEQGDL Sbjct 240 IFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLS 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFN MV GLRERERVRDLFGRHVGREVAAAAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVFVDIVGSTQLV ++PAA VV LLNRFF ++V+EV+ H GL+NKF GDA+LA+FGAP Sbjct 360 VAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PEDAALA ARAIADRLA+EMPE QAGIGVAAGQ+VAGNVGA +RFEYTV+G+PVN Sbjct 420 NRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS+P+RLLASS TL ASE E A WSLGETVTLRGH+QP RLA P Sbjct 480 EAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASP 533 >gi|289446916|ref|ZP_06436660.1| adenylate cyclase [Mycobacterium tuberculosis CPHL_A] gi|289419874|gb|EFD17075.1| adenylate cyclase [Mycobacterium tuberculosis CPHL_A] Length=567 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/534 (67%), Positives = 418/534 (79%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MP++K + L A+ET++ + G+ PETPAYGSWLLGRVSESP R VRI+ ++TV I+ Sbjct 1 MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ G++V +++T AFP PS+ DAP WV+FG+ P Y LA +GTYW+T + RA +R Sbjct 61 TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER PS + R+ L+P RVA L LW AL +YGLANR+F+ LFS+ + Sbjct 120 WAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVI 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GV+ AT+CYL TEFALRP+AA+ALE G PR GI+GRTM VW L SGVP G+A TA Sbjct 180 GVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L+ Q VLIL LIFGF++MWILAWLTA PVRVVR AL RVEQGDL Sbjct 240 IFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLS 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFN MV GLRERERVRDLFGRHVGREVAAAAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVFVDIVGSTQLV ++PAA VV LLNRFF ++V+EV+ H GL+NKF GDA+L +FGAP Sbjct 360 VAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLTVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PEDAALA ARAIADRLA+EMPE QAGIGVAAGQ+VAGNVGA +RFEYTV+G+PVN Sbjct 420 NRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS+P+RLLASS TL ASE E A WSLGETVTLRGH+QP RLA P Sbjct 480 EAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASP 533 >gi|15608460|ref|NP_215836.1| adenylate cyclase [Mycobacterium tuberculosis H37Rv] gi|148661108|ref|YP_001282631.1| putative adenylate cyclase [Mycobacterium tuberculosis H37Ra] gi|167967592|ref|ZP_02549869.1| putative adenylate cyclase [Mycobacterium tuberculosis H37Ra] gi|1722970|sp|Q10633.1|Y1320_MYCTU RecName: Full=Uncharacterized protein Rv1320c/MT1362 gi|1340086|emb|CAA98107.1| POSSIBLE ADENYLATE CYCLASE (ATP PYROPHOSPHATE-LYASE) (ADENYLYL CYCLASE) [Mycobacterium tuberculosis H37Rv] gi|148505260|gb|ABQ73069.1| putative adenylate cyclase [Mycobacterium tuberculosis H37Ra] Length=567 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/534 (67%), Positives = 418/534 (79%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MP++K + L A+ET++ + G+ PETPAYGSWLLGRVSESP R VRI+ ++TV I+ Sbjct 1 MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ G++V +++T AFP PS+ DAP WV+FG+ P Y LA +GTYW+T + RA +R Sbjct 61 TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER PS + R+ L+P RVA L LW AL +YGLANR+F+ LFS+ + Sbjct 120 WAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVI 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GV+ AT+CYL TEFALRP+AA+ALE G PR GI+GRTM VW L SGVP G+A TA Sbjct 180 GVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L+ Q VLIL LIFGF++MWILAWLTA PVRVVR AL RVEQGDL Sbjct 240 IFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLS 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFN MV GLRERERVRDLFGRHVGREVAAAAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVFVDIVGSTQLV ++PAA VV LLNRFF ++V+EV+ H GL+NKF GDA+LA+FGAP Sbjct 360 VAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PEDAALA ARAIADRLA+EMPE QAGIGVAAGQ+VAGNVGA +RFEYTV+G+PVN Sbjct 420 NRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS+P+RLLASS TL ASE E A WSLGETVTLRGH+QP RL P Sbjct 480 EAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLTSP 533 >gi|339631388|ref|YP_004723030.1| adenylate cyclase [Mycobacterium africanum GM041182] gi|339330744|emb|CCC26415.1| putative adenylate cyclase (ATP pyrophosphate-lyase) [Mycobacterium africanum GM041182] Length=567 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/534 (67%), Positives = 418/534 (79%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 MP++K + L A+ET++ + G+ PETPAYGSWLLGRVSESP R VRI+ ++TV I+ Sbjct 1 MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ G++V +++T AFP S+ DAP WV+FG+ P Y LA +GTYW+T + RA +R Sbjct 61 TNVIGLIVGAMLLTVAFPKSSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER PS + R+ L+P RVA L LW AL +YGLANR+F+ LFS+ + Sbjct 120 WAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVI 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GV+ AT+CYL TEFALRP+AA+ALE G PR GI+GRTM VW L SGVP G+A TA Sbjct 180 GVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L+ Q VLIL LIFGF++MWILAWLTA PVRVVR AL RVEQGDL Sbjct 240 IFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLS 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFN MV GLRERERVRDLFGRHVGREVAAAAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVFVDIVGSTQLV ++PAA VV LLNRFF ++V+EV+ H GL+NKF GDA+LA+FGAP Sbjct 360 VAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PEDAALA ARAIADRLA+EMPE QAGIGVAAGQ+VAGNVGA +RFEYTV+G+PVN Sbjct 420 NRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS+P+RLLASS TL ASE E A WSLGETVTLRGH+QP RLA P Sbjct 480 EAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASP 533 >gi|340626336|ref|YP_004744788.1| putative adenylate cyclase [Mycobacterium canettii CIPT 140010059] gi|340004526|emb|CCC43669.1| putative adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) [Mycobacterium canettii CIPT 140010059] Length=567 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/534 (67%), Positives = 418/534 (79%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M ++K + L A+ET++ + G+ PETPAYGSWLLGRVSESP R VRI+ ++TV I+ Sbjct 1 MQSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ G++V +++T AFP PS+ DAP WV+FG+ P Y LA +GTYW+T + RA +R Sbjct 61 TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARA-LR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER PS + R+ L+P RVA L LW AL +YGLANR+F+ LFS+ + Sbjct 120 WAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVI 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GV+ AT+CYL TEFALRP+AA+ALE G PR GI+GRTM VW L SGVP G+A TA Sbjct 180 GVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L+ Q VLIL LIFGF++MWILAWLTA PVRVVR AL RVEQGDL Sbjct 240 IFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLS 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 GDLVVFDGTELGELQRGFN MV GLRERERVRDLFGRHVGREVAAAAERERP+LGGE+RH Sbjct 300 GDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVFVDIVGSTQLV ++PAA VV LLNRFF ++V+EV+ H GL+NKF GDA+LA+FGAP Sbjct 360 VAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 NRL PEDAALA ARAIADRLA+EMPE QAGIGVAAGQ+VAGNVGA +RFEYTV+G+PVN Sbjct 420 NRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAKS+P+RLLASS TL ASE E A WSLGETVTLRGH+QP RLA P Sbjct 480 EAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASP 533 >gi|333989962|ref|YP_004522576.1| adenylate cyclase [Mycobacterium sp. JDM601] gi|333485930|gb|AEF35322.1| adenylate cyclase [Mycobacterium sp. JDM601] Length=524 Score = 691 bits (1784), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/524 (67%), Positives = 421/524 (81%), Gaps = 1/524 (0%) Query 11 LGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVAL 70 +G+ LE +TRQ +LPETP YGSWLLGRVSES R +RI+ I+TV I+ NL GI V Sbjct 1 MGRVLELLTRQTDRLPETPEYGSWLLGRVSESQYLRRIRIQFILTVVIVGTNLIGIGVEA 60 Query 71 LVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQ 130 L++ AFP PS++ DAP W+T+GV PAY LAL GTYWIT R ++ +RWAI E+ P++ Sbjct 61 LLLAVAFPSPSVFFDAPGWLTYGVVPAYIVLALIFGTYWITRRTIK-KLRWAIREQQPTR 119 Query 131 ADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVATNCYL 190 D RN L P+RVA V L LW + L LYG+A+ F+ I+ F+V +CG+ VAT CYL Sbjct 120 VDERNAFLAPWRVAQVVLALWGVAAMLFTVLYGMADNYFIPIVAFTVGVCGIQVATACYL 179 Query 191 FTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLT 250 TEFALRPVAA+AL AG PPRRF GIMGRTM VW L SGVPV GIA TA++ L++ NL+ Sbjct 180 CTEFALRPVAAQALAAGPPPRRFFSGIMGRTMMVWLLSSGVPVLGIALTAIFALVLKNLS 239 Query 251 ETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTE 310 TQ AVL++++ T +FGFL+MWIL+WLTAAPVRVVRAAL+RVEQG+L DLVVFDGTE Sbjct 240 MTQFGVAVLVVAVATAVFGFLLMWILSWLTAAPVRVVRAALRRVEQGNLGADLVVFDGTE 299 Query 311 LGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVG 370 LGELQ GFNAMV+GLRERERVRDLFGRHVGREVAAAAER+R QLGGE+RH AV+FVDI+G Sbjct 300 LGELQSGFNAMVHGLRERERVRDLFGRHVGREVAAAAERDRIQLGGEERHVAVLFVDIIG 359 Query 371 STQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAA 430 STQ+V +PA VV LLNRFFA+VV+EVDRH GLINKF GDA+LAIFGAPN LD+PED A Sbjct 360 STQIVTAKPATEVVTLLNRFFAVVVDEVDRHRGLINKFEGDASLAIFGAPNHLDQPEDEA 419 Query 431 LAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAK 490 LAA RAI RLA+E+PE++AGIGVAAGQ+VAGNVGAK+RFEYTV+G+PVN+AARL ELAK Sbjct 420 LAAGRAILSRLADEVPEIRAGIGVAAGQVVAGNVGAKERFEYTVIGEPVNEAARLSELAK 479 Query 491 SHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +LL ++ TL AAS +E+AHW LG++V LRG++QPT LA P Sbjct 480 IRELQLLTTARTLRAASISEQAHWVLGDSVVLRGYDQPTVLAGP 523 >gi|183984050|ref|YP_001852341.1| adenylate cyclase [Mycobacterium marinum M] gi|183177376|gb|ACC42486.1| adenylate cyclase [Mycobacterium marinum M] Length=534 Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/534 (67%), Positives = 422/534 (80%), Gaps = 1/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M + + QRL + + Q QL E PAYGSWLLG+V E+ R +RI+ I+T I+ Sbjct 1 MVSTTAVGQRLRRVFVQVIDQGDQLTEPPAYGSWLLGQVLENQRSRRIRIQVILTSVIVF 60 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 ANL GI V LL+ A P P+++TDAPWWVTF VAPAY +AL +GTYWIT R V+ ++R Sbjct 61 ANLVGIGVVLLIAIVAIPAPNVFTDAPWWVTFVVAPAYIVVALVLGTYWITRRTVQ-TLR 119 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WA+EER PS+AD R+T +P +VA LW +G LYGLAN +F+ LF+V+IC Sbjct 120 WALEERPPSRADARSTFRVPRQVALATATLWGVGAVASTILYGLANPLFIPRFLFTVSIC 179 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 GVLVAT YL TEFALRPVAA+ALEA PP+RFAPGIMGRTM VW LGSG P+ GI A Sbjct 180 GVLVATGAYLLTEFALRPVAAQALEAAPPPQRFAPGIMGRTMMVWLLGSGGPLVGINLMA 239 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 + L+ +LT+ Q A V+I+S TLIFGF++MWI++WLTA PVRVVRAAL RV GDL+ Sbjct 240 ISELVKGSLTKVQFAIGVVIVSTGTLIFGFILMWIMSWLTATPVRVVRAALNRVANGDLQ 299 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 DLVVFDGTELGELQRGFN MV+GLRERERVRDLFGRHVGREVA AAERERP+LGGE+RH Sbjct 300 RDLVVFDGTELGELQRGFNTMVDGLRERERVRDLFGRHVGREVAIAAERERPKLGGEERH 359 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AVVF+DIVGST+LV +QP A VV LLNRFFA+VV+EVDRH GL+NKFAGDA+LAIFGAP Sbjct 360 VAVVFIDIVGSTKLVTSQPPADVVALLNRFFAVVVDEVDRHCGLVNKFAGDASLAIFGAP 419 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 N L+RPED ALAAAR IA RLA+E+PE +AGIGVAAGQ+VAGNVG+K+RFEYTV+G+PVN Sbjct 420 NHLERPEDQALAAARTIAARLASEVPECRAGIGVAAGQVVAGNVGSKERFEYTVIGEPVN 479 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAK HP RLLAS L AS ERA WS+G+TVTLRGH+QPTRLA P Sbjct 480 EAARLCELAKDHPGRLLASGAALDGASHDERARWSVGKTVTLRGHDQPTRLAAP 533 >gi|118473953|ref|YP_889179.1| adenylate cyclase, family protein 3 [Mycobacterium smegmatis str. MC2 155] gi|118175240|gb|ABK76136.1| adenylate cyclase, family protein 3 [Mycobacterium smegmatis str. MC2 155] Length=535 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/537 (64%), Positives = 424/537 (79%), Gaps = 6/537 (1%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPE-TPAYGSWLLGRVSESPSRRWVRIKRIVTVYIM 59 M A ++A++LG+ LET+TRQ +LP TP YGSW+LGRV+ES SRR +RI+ I+T +++ Sbjct 1 MNADNSLARQLGRVLETVTRQNSRLPSGTPEYGSWILGRVTESQSRRRIRIQLILTTFVV 60 Query 60 TANLTGIVVALLVVTFAFPVPSIYTD--APWWVTFGVAPAYATLALAIGTYWITTRIVRA 117 ANL GI V+ LV+T FP PS++ AP+ T+ VAPAY AL +G W T R++ Sbjct 61 IANLLGIAVSFLVLTVLFPSPSVFDARVAPY--TYIVAPAYVVGALVVGVIWATNRVI-G 117 Query 118 SIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSV 177 ++RWA+EER P+ D RNT PFR+ V LILW G ALL TLYG+ + F+ +L + Sbjct 118 NVRWALEERPPTPQDQRNTFFAPFRLTRVLLILWAAGTALLTTLYGMVDTNFIPKVLLGI 177 Query 178 TICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIA 237 + G++V+ +C+LFTEFALRPVAA+ALEAG PP R APGIMGRTM VW+LGSGVP+ GI Sbjct 178 SFPGIVVSVSCHLFTEFALRPVAAQALEAGPPPVRLAPGIMGRTMVVWALGSGVPILGIL 237 Query 238 TTALYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQG 297 ++ + + NLT TQ A AV+ L++ L+FGF++MWIL+WLTA P+RVVRAAL RVEQG Sbjct 238 LAGVFAVTLENLTPTQFAYAVMGLAVFALVFGFILMWILSWLTATPIRVVRAALNRVEQG 297 Query 298 DLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGE 357 DL +LVVFDGTELG+LQRGFN+MV+GLRERERVRDLFGRHVGREVA AE+++ LGGE Sbjct 298 DLDTNLVVFDGTELGQLQRGFNSMVHGLRERERVRDLFGRHVGREVAVLAEQQKFTLGGE 357 Query 358 DRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIF 417 +RHAAVVFVD++GSTQLV ++PA VV+LLNRFFA++V+EVD H GL+NKF GDA LA+F Sbjct 358 ERHAAVVFVDVIGSTQLVTSRPAVEVVELLNRFFAVIVDEVDAHRGLVNKFEGDAVLAVF 417 Query 418 GAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGK 477 GAP LD ED AL AAR IA RL E+PE+ AGIGVAAGQ+VAGNVGAKQRFEYTV+G+ Sbjct 418 GAPVALDNAEDEALGAARGIARRLREEVPELDAGIGVAAGQVVAGNVGAKQRFEYTVIGE 477 Query 478 PVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 PVN+AARLCE AKS P ++ASSDTL ASE+ERA WSLGE+VTLRG ++PTRLAVP Sbjct 478 PVNEAARLCEFAKSVPGHVVASSDTLANASESERARWSLGESVTLRGLDEPTRLAVP 534 >gi|120405263|ref|YP_955092.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] gi|119958081|gb|ABM15086.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] Length=536 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/534 (65%), Positives = 425/534 (80%), Gaps = 2/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A K++ RLG+ LE +TRQ G+L ETP YGSWLLG+ ES +RR +RI+ I+T ++ Sbjct 1 MNATKSVPYRLGRVLERVTRQSGRL-ETPDYGSWLLGKPEESQARRRIRIQVILTFLLLF 59 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ GI V+LL+ T A PVPS+++DAP W+TFGV PAY +AL +GT WIT+R V S+R Sbjct 60 TNILGIAVSLLLNTVAIPVPSVFSDAPAWLTFGVVPAYMVVALVLGTAWITSRTV-GSLR 118 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER+P++ D RN + P RVA + L+ W G ALL LYGL + F+ LF+V Sbjct 119 WAIEERSPTRTDQRNVFVAPSRVAQMLLLFWGFGAALLTLLYGLQDSAFIPRFLFAVGFP 178 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 G++VAT CY+ TEFALRPVAA+ALEAGRPPRR A G+MGRTMTVW L SGVPV GI A Sbjct 179 GIVVATACYMITEFALRPVAAQALEAGRPPRRLAHGVMGRTMTVWLLSSGVPVLGILLLA 238 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L + NL+ TQ A AV+I+S+ L+FG ++MW+L+WL A PVRVVR+ALK VE GDL Sbjct 239 IFTLSLRNLSATQFAVAVMIISVVALMFGLILMWLLSWLIATPVRVVRSALKHVEDGDLD 298 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 ++VVFDGTELGELQRGFN+MV+GLRERERVRDLFGRHVGREVA AAE+++ +LGGE+RH Sbjct 299 CNVVVFDGTELGELQRGFNSMVHGLRERERVRDLFGRHVGREVARAAEKQKIELGGEERH 358 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAV+FVDI+GSTQLV ++PA VV+LLNRFF +VV EVD HHGL+NKF GDA LA+FGAP Sbjct 359 AAVIFVDIIGSTQLVTSRPAVEVVELLNRFFDVVVEEVDNHHGLVNKFEGDAVLAVFGAP 418 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 LD E AL+AARA+A RL E+PE AGIGVAAGQ+VAGNVGAKQRFEYTV+G+PVN Sbjct 419 VSLDSAETEALSAARAMARRLRTEVPECPAGIGVAAGQVVAGNVGAKQRFEYTVIGEPVN 478 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCELAK+ PA L+AS+D + A+E+ERA W LGETVTLRGH+QPTRLA P Sbjct 479 EAARLCELAKNVPALLVASADAVGGATESERALWKLGETVTLRGHDQPTRLATP 532 >gi|145222924|ref|YP_001133602.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315443387|ref|YP_004076266.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] gi|145215410|gb|ABP44814.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315261690|gb|ADT98431.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] Length=536 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/534 (65%), Positives = 422/534 (80%), Gaps = 2/534 (0%) Query 1 MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT 60 M A K++ RLG+ LE +TRQ G+L +TP YGSWLLGR +ES SRR VRI+ I+T +I+ Sbjct 1 MNATKSVPYRLGRVLERVTRQSGRL-DTPGYGSWLLGRPAESQSRRRVRIQIILTFFILF 59 Query 61 ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR 120 N+ GI V+LL+ T A PVPS+++DAP W+TFGV PAY +AL GT WIT+R VR S+R Sbjct 60 TNIMGIAVSLLLNTIAIPVPSVFSDAPAWLTFGVTPAYMLVALFFGTAWITSRTVR-SLR 118 Query 121 WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC 180 WAIEER P+ D RN L P RVA L+LW +G LL LYGL + F+ LF+V Sbjct 119 WAIEERQPTSTDQRNVFLAPARVAQKLLLLWGVGAVLLTVLYGLQDTAFIPRFLFAVGFP 178 Query 181 GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA 240 G++VAT CY+ TEFALRP+AA+ALEAGRPPRR A G+MGRTMTVW L SGVPV GI A Sbjct 179 GIVVATACYMITEFALRPIAAQALEAGRPPRRLAHGVMGRTMTVWLLSSGVPVLGILLLA 238 Query 241 LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR 300 ++ L + NL+ TQ A AV+ ++ L+FG +MW+L+WL A PVRVVR+ALK+VE GDL Sbjct 239 VFSLSLKNLSATQFAVAVIFIAAFALVFGLTLMWLLSWLIATPVRVVRSALKQVEDGDLD 298 Query 301 GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH 360 +LVVFDGTELGELQRGFN+MV+GLRERERVRDLFGRHVGREVA AAE+++ +LGGE+R Sbjct 299 CNLVVFDGTELGELQRGFNSMVHGLRERERVRDLFGRHVGREVALAAEKQQVELGGEERR 358 Query 361 AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP 420 AAV+FVDI+GST+LV ++PAA VV+LLNRFF +VV+EVD+HHGL+NKF GDA LA+FGAP Sbjct 359 AAVIFVDIIGSTKLVTSRPAAEVVELLNRFFDVVVDEVDKHHGLVNKFEGDAVLAVFGAP 418 Query 421 NRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN 480 LD E ALAAARA++ RLA E+PE AGIGVA+GQ+VAGNVGAK+RFEYTV+G+PVN Sbjct 419 VSLDNAEAEALAAARAMSRRLAAEVPECTAGIGVASGQVVAGNVGAKERFEYTVIGEPVN 478 Query 481 QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVP 534 +AARLCEL+K L+AS+D +H A+ETER HW LGETVTLRGH +PT LA P Sbjct 479 EAARLCELSKKIDGHLVASADAVHNATETERRHWELGETVTLRGHAEPTTLATP 532 Lambda K H 0.324 0.136 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1174515528420 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40