BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1345 Length=521 Score E Sequences producing significant alignments: (Bits) Value gi|15608485|ref|NP_215861.1| long-chain-fatty-acid--[acyl-carrie... 1032 0.0 gi|344219176|gb|AEM99806.1| long-chain-fatty-acid--[acyl-carrier... 1030 0.0 gi|339294324|gb|AEJ46435.1| fadD33, long-chain-fatty-acid--[acyl... 997 0.0 gi|15840800|ref|NP_335837.1| long-chain-fatty-acid--[acyl-carrie... 917 0.0 gi|254820861|ref|ZP_05225862.1| long-chain-fatty-acid--[acyl-car... 731 0.0 gi|118466817|ref|YP_882060.1| long-chain-fatty-acid--[acyl-carri... 715 0.0 gi|254775351|ref|ZP_05216867.1| long-chain-fatty-acid--[acyl-car... 714 0.0 gi|41407652|ref|NP_960488.1| acyl-CoA synthetase [Mycobacterium ... 711 0.0 gi|333990172|ref|YP_004522786.1| polyketide synthase Pks16 [Myco... 650 0.0 gi|118473699|ref|YP_886489.1| long-chain-fatty-acid--[acyl-carri... 644 0.0 gi|120402942|ref|YP_952771.1| long-chain-fatty-acid--[acyl-carri... 636 2e-180 gi|315445358|ref|YP_004078237.1| acyl-CoA synthetase (AMP-formin... 622 3e-176 gi|145224990|ref|YP_001135668.1| long-chain-fatty-acid--[acyl-ca... 622 4e-176 gi|108799309|ref|YP_639506.1| long-chain-fatty-acid--[acyl-carri... 621 1e-175 gi|336462100|gb|EGO40942.1| acyl-CoA synthetase (AMP-forming)/AM... 595 4e-168 gi|41406124|ref|NP_958960.1| acyl-CoA synthetase [Mycobacterium ... 593 3e-167 gi|118462530|ref|YP_879330.1| long-chain-fatty-acid--[acyl-carri... 590 1e-166 gi|119867809|ref|YP_937761.1| long-chain-fatty-acid--[acyl-carri... 588 7e-166 gi|108798691|ref|YP_638888.1| long-chain-fatty-acid--[acyl-carri... 586 4e-165 gi|254819093|ref|ZP_05224094.1| long-chain-fatty-acid--[acyl-car... 575 5e-162 gi|342860256|ref|ZP_08716908.1| long-chain-fatty-acid--[acyl-car... 574 2e-161 gi|343925521|ref|ZP_08765040.1| putative fatty-acid--CoA ligase ... 501 9e-140 gi|296392813|ref|YP_003657697.1| AMP-dependent synthetase and li... 478 2e-132 gi|325000634|ref|ZP_08121746.1| long-chain-fatty-acid--CoA ligas... 261 2e-67 gi|325676252|ref|ZP_08155931.1| acyl-CoA synthetase [Rhodococcus... 259 1e-66 gi|126438180|ref|YP_001073871.1| long-chain-fatty-acid--CoA liga... 257 4e-66 gi|134097414|ref|YP_001103075.1| long-chain-fatty-acid--CoA liga... 256 5e-66 gi|256374801|ref|YP_003098461.1| long-chain-fatty-acid--CoA liga... 256 6e-66 gi|312138679|ref|YP_004006015.1| acyl-CoA ligase/synthetase [Rho... 256 7e-66 gi|145225792|ref|YP_001136470.1| long-chain-fatty-acid--CoA liga... 255 2e-65 gi|257057208|ref|YP_003135040.1| long-chain-fatty-acid--CoA liga... 254 2e-65 gi|226365171|ref|YP_002782954.1| long-chain-fatty-acid--CoA liga... 254 2e-65 gi|108802198|ref|YP_642395.1| long-chain-fatty-acid--CoA ligase ... 254 2e-65 gi|229494919|ref|ZP_04388670.1| acyl-CoA synthase [Rhodococcus e... 254 3e-65 gi|111022658|ref|YP_705630.1| long-chain-fatty-acid--CoA ligase ... 253 5e-65 gi|118619726|ref|YP_908058.1| acyl-CoA synthetase [Mycobacterium... 253 6e-65 gi|226307814|ref|YP_002767774.1| fatty-acid--CoA ligase [Rhodoco... 253 8e-65 gi|183984446|ref|YP_001852737.1| polyketide synthase Pks16 [Myco... 252 1e-64 gi|158315222|ref|YP_001507730.1| long-chain-fatty-acid--CoA liga... 252 1e-64 gi|120402066|ref|YP_951895.1| long-chain-fatty-acid--CoA ligase ... 251 2e-64 gi|145222525|ref|YP_001133203.1| long-chain-fatty-acid--CoA liga... 249 6e-64 gi|240169904|ref|ZP_04748563.1| acyl-CoA synthetase [Mycobacteri... 249 1e-63 gi|169628233|ref|YP_001701882.1| long-chain-fatty-acid--CoA liga... 249 1e-63 gi|331694717|ref|YP_004330956.1| Long-chain-fatty-acid--(acyl-ca... 248 1e-63 gi|120405748|ref|YP_955577.1| long-chain-fatty-acid--CoA ligase ... 246 5e-63 gi|183980208|ref|YP_001848499.1| polyketide synthase Pks16_1 [My... 246 7e-63 gi|254821214|ref|ZP_05226215.1| long-chain-fatty-acid--CoA ligas... 246 1e-62 gi|118619948|ref|YP_908280.1| acyl-CoA synthetase [Mycobacterium... 244 3e-62 gi|342861613|ref|ZP_08718259.1| long-chain-fatty-acid--CoA ligas... 243 8e-62 gi|183984938|ref|YP_001853229.1| acyl-coenzyme A synthetase [Myc... 242 1e-61 >gi|15608485|ref|NP_215861.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis H37Rv] gi|31792541|ref|NP_855034.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium bovis AF2122/97] gi|121637276|ref|YP_977499.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium bovis BCG str. Pasteur 1173P2] 76 more sequence titles Length=521 Score = 1032 bits (2668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 521/521 (100%), Positives = 521/521 (100%), Gaps = 0/521 (0%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV Sbjct 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA Sbjct 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL 180 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL Sbjct 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL 180 Query 181 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL 240 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL Sbjct 181 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL 240 Query 241 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF 300 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF Sbjct 241 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF 300 Query 301 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ 360 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ Sbjct 301 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ 360 Query 361 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI 420 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI Sbjct 361 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI 420 Query 421 AGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR 480 AGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR Sbjct 421 AGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR 480 Query 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD Sbjct 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 >gi|344219176|gb|AEM99806.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis CTRI-2] Length=521 Score = 1030 bits (2664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/521 (99%), Positives = 520/521 (99%), Gaps = 0/521 (0%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV Sbjct 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA Sbjct 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL 180 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL Sbjct 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNL 180 Query 181 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL 240 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL Sbjct 181 RGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWL 240 Query 241 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF 300 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF Sbjct 241 SDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGF 300 Query 301 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ 360 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ Sbjct 301 DAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQ 360 Query 361 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI 420 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI Sbjct 361 AAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISI 420 Query 421 AGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR 480 AGRNIFP EVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR Sbjct 421 AGRNIFPKEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR 480 Query 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD Sbjct 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 >gi|339294324|gb|AEJ46435.1| fadD33, long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis CCDC5079] gi|339297963|gb|AEJ50073.1| fadD33, long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis CCDC5180] Length=502 Score = 997 bits (2577), Expect = 0.0, Method: Compositional matrix adjust. Identities = 502/502 (100%), Positives = 502/502 (100%), Gaps = 0/502 (0%) Query 20 MVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGA 79 MVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGA Sbjct 1 MVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGA 60 Query 80 AVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAA 139 AVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAA Sbjct 61 AVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAA 120 Query 140 HTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSW 199 HTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSW Sbjct 121 HTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSW 180 Query 200 LPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIG 259 LPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIG Sbjct 181 LPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIG 240 Query 260 KYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVT 319 KYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVT Sbjct 241 KYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVT 300 Query 320 VPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASM 379 VPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASM Sbjct 301 VPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASM 360 Query 380 MAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRG 439 MAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRG Sbjct 361 MAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRG 420 Query 440 VREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGS 499 VREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGS Sbjct 421 VREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGS 480 Query 500 LPRTSSGKLRRLAVRRSLEMAD 521 LPRTSSGKLRRLAVRRSLEMAD Sbjct 481 LPRTSSGKLRRLAVRRSLEMAD 502 >gi|15840800|ref|NP_335837.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis CDC1551] gi|294994903|ref|ZP_06800594.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis 210] gi|13880995|gb|AAK45651.1| AMP-binding family protein [Mycobacterium tuberculosis CDC1551] Length=465 Score = 917 bits (2370), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/465 (99%), Positives = 465/465 (100%), Gaps = 0/465 (0%) Query 57 VGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQG 116 +GLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQG Sbjct 1 MGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQG 60 Query 117 SYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAV 176 SYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAV Sbjct 61 SYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAV 120 Query 177 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW 236 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW Sbjct 121 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW 180 Query 237 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA 296 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA Sbjct 181 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA 240 Query 297 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRIS 356 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRIS Sbjct 241 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRIS 300 Query 357 CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKE 416 CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKE Sbjct 301 CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKE 360 Query 417 VISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAE 476 VISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAE Sbjct 361 VISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAE 420 Query 477 LIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 LIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD Sbjct 421 LIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 465 >gi|254820861|ref|ZP_05225862.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium intracellulare ATCC 13950] Length=522 Score = 731 bits (1888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/527 (71%), Positives = 429/527 (82%), Gaps = 11/527 (2%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELA LT +M+ DL+V DRE S W RHPWPEVHGLAESVAAWLLD RPAAVGLV Sbjct 1 MSELATALTVAMRGGTSDLVVFDREASAWHRHPWPEVHGLAESVAAWLLDRGRPAAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVE VAAIQGAWL GA+VSILPGPVRGA +RWADATLTRF GIGVRTVLS GSYL Sbjct 61 GEPTVEFVAAIQGAWLTGASVSILPGPVRGAEGRRWADATLTRFRGIGVRTVLSHGSYLD 120 Query 121 RLRSVDTAGV----TIGDLSTAAHTNRSA--TPVASEGPAVLQGTAGSTGAPRTAILSPG 174 L+S+D AG+ + D+ AA T R+ P E PA+LQGTAGSTG+P+TA LSP Sbjct 121 GLQSLDPAGLDEDMVVEDVGPAARTGRTCGEPPARRENPAILQGTAGSTGSPKTAALSPR 180 Query 175 AVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPF 234 AVL+NLRGLN R+ A DVGCSWLPLYHDMGL+F+L+++L G +WL+PT+AFTASPF Sbjct 181 AVLANLRGLNHRLSVTPA-DVGCSWLPLYHDMGLSFLLASSLGGMSVWLSPTSAFTASPF 239 Query 235 RWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEA 294 RWLSWLS+S AT+TAAPNFAYNL+G+YARRVS+VDLGA+RV +NGGEPVDC+G RFA+A Sbjct 240 RWLSWLSESRATITAAPNFAYNLVGRYARRVSDVDLGAVRVAINGGEPVDCEGFERFADA 299 Query 295 MAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVR 354 M PFGFDAGA PSYGLAESTCAV+VP PG GL V D +G+ +HA+LG PI G E+R Sbjct 300 MGPFGFDAGAATPSYGLAESTCAVSVPAPGTGLRFADVTDEAGSRRHAMLGEPIAGTEIR 359 Query 355 ISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRA 414 IS D G+ IGEIEIRGASMM GYLG P+D + WF TGDLG++ GGLVVCGRA Sbjct 360 ISPRDDTHGD----IGEIEIRGASMMDGYLGHDPVDRESWFPTGDLGFIADGGLVVCGRA 415 Query 415 KEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANAR 474 KE+I+IAGRNIFPTE+E VAA VRGVREGAVVAL TG+RS RPGL+VAAEFRG D+A AR Sbjct 416 KELITIAGRNIFPTEIETVAAGVRGVREGAVVALATGERSARPGLIVAAEFRGADQAGAR 475 Query 475 AELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 A++I RVAS CG+VPSDV+F++PGSLPRTSSGKLRRL VRRSLE D Sbjct 476 ADVIARVASVCGVVPSDVIFMAPGSLPRTSSGKLRRLEVRRSLEAVD 522 >gi|118466817|ref|YP_882060.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium avium 104] gi|118168104|gb|ABK69001.1| acyl-CoA synthase [Mycobacterium avium 104] Length=521 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/526 (71%), Positives = 421/526 (81%), Gaps = 10/526 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELAA LT +M+ DL+V DRE++ W RH WPEVHGLAE +AAWLLD DRPAA+GLV Sbjct 1 MSELAAALTAAMRTGGSDLVVFDRESAAWRRHRWPEVHGLAEGIAAWLLDRDRPAALGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT+E VAAI GAWLAGA VSILPGPVRGA +RWAD TLTRF GIGVRTVLS GS+L Sbjct 61 GEPTLEFVAAIVGAWLAGAGVSILPGPVRGAEGRRWADTTLTRFAGIGVRTVLSHGSHLD 120 Query 121 RLRSVDTA---GVTIGDLSTAAHTNRSAT--PVASEGPAVLQGTAGSTGAPRTAILSPGA 175 L+++D + + + DL+ AA+T R P PA+LQGTAGSTG P+TA LSP A Sbjct 121 ALQALDPSRPDEMVVEDLAVAANTGRRCPEPPAPHANPAILQGTAGSTGTPKTAALSPDA 180 Query 176 VLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFR 235 VL+NLRGLN R+G A DVGCSWLPLYHDMGL+F+L++AL G LWLAPT+AFTASPFR Sbjct 181 VLANLRGLNARLGVTPA-DVGCSWLPLYHDMGLSFLLASALGGMSLWLAPTSAFTASPFR 239 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAM 295 WL+WLS+S AT+TAAPNFAYNL+GKYARRVS VDLGALRV +NGGEPVDC G RFA AM Sbjct 240 WLAWLSESRATITAAPNFAYNLVGKYARRVSGVDLGALRVAINGGEPVDCAGFERFATAM 299 Query 296 APFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRI 355 APFGFDAGA PSYGLAESTCAV+VP PG GL V D +G +HAVLG PIPG E+RI Sbjct 300 APFGFDAGAATPSYGLAESTCAVSVPAPGTGLRFADVSDETGTRRHAVLGAPIPGTEIRI 359 Query 356 SCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAK 415 S + IGEIEIRGASMM GYLG PID +WF TGDLG+ GGLVVCGRAK Sbjct 360 S----PRHDVPDGIGEIEIRGASMMDGYLGHAPIDHQNWFPTGDLGFFSDGGLVVCGRAK 415 Query 416 EVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARA 475 E+I++AGRNIFPTE+E VAAQV GVREGAVVALGTG+ S RPGL++AAEF G D A ARA Sbjct 416 ELITLAGRNIFPTEIETVAAQVPGVREGAVVALGTGENSARPGLIIAAEFAGRDRAGARA 475 Query 476 ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 E+IQRVAS CG+VPSDV+F++PGSLPRTSSGKLRRL VRRSLE D Sbjct 476 EVIQRVASVCGVVPSDVIFMAPGSLPRTSSGKLRRLDVRRSLEAVD 521 >gi|254775351|ref|ZP_05216867.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium avium subsp. avium ATCC 25291] Length=521 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/526 (71%), Positives = 420/526 (80%), Gaps = 10/526 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELAA LT +M+ DL+V DRE++ W RH WPEVHGLAE +AAWLLD DRPAA+GLV Sbjct 1 MSELAAALTAAMRTGGSDLVVFDRESAAWRRHRWPEVHGLAEGIAAWLLDRDRPAALGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT+E VAAI GAWLAGA VSILPGPVRGA +RWAD TLTRF GIGVRTVLS S+L Sbjct 61 GEPTLEFVAAIMGAWLAGAGVSILPGPVRGAEGRRWADTTLTRFAGIGVRTVLSHRSHLD 120 Query 121 RLRSVDTA---GVTIGDLSTAAHTNRSAT--PVASEGPAVLQGTAGSTGAPRTAILSPGA 175 L+++D + + + DL AA+T R P PA+LQGTAGSTG P+TA LSP A Sbjct 121 ALQALDPSRPDEMVVEDLGVAANTGRRCPDPPAPHANPAILQGTAGSTGTPKTAALSPDA 180 Query 176 VLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFR 235 VL+NLRGLN R+G A DVGCSWLPLYHDMGL+F+L++AL G LWLAPT+AFTASPFR Sbjct 181 VLANLRGLNARLGVTPA-DVGCSWLPLYHDMGLSFLLASALGGMSLWLAPTSAFTASPFR 239 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAM 295 WL+WLS+S AT+TAAPNFAYNL+GKYARRVS VDLGALRV +NGGEPVDC G RFA AM Sbjct 240 WLAWLSESRATITAAPNFAYNLVGKYARRVSGVDLGALRVAINGGEPVDCAGFERFATAM 299 Query 296 APFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRI 355 APFGFDAGA PSYGLAESTCAV+VP PG GL V D +G +HAVLG PIPG E+RI Sbjct 300 APFGFDAGAATPSYGLAESTCAVSVPAPGTGLRFADVSDETGTRRHAVLGEPIPGTEIRI 359 Query 356 SCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAK 415 S +A IGEIEIRGASMM GYLG PID +WF TGDLG+ GGLVVCGRAK Sbjct 360 S----PRHDAPDGIGEIEIRGASMMDGYLGHAPIDHQNWFPTGDLGFFSDGGLVVCGRAK 415 Query 416 EVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARA 475 E+I++AGRNIFPTE+E VAAQV GVREGAVVALGTG+ S RPGL++AAEF G D A ARA Sbjct 416 ELITLAGRNIFPTEIETVAAQVPGVREGAVVALGTGENSARPGLIIAAEFAGRDRAGARA 475 Query 476 ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 E+IQRVAS CG+VPSDV+F++PGSLPRTSSGKLRRL VRRSLE D Sbjct 476 EVIQRVASVCGVVPSDVIFMAPGSLPRTSSGKLRRLDVRRSLEAVD 521 >gi|41407652|ref|NP_960488.1| acyl-CoA synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|81700614|sp|Q73ZP7.1|MBTM_MYCPA RecName: Full=Long-chain-fatty-acid--[acyl-carrier-protein] ligase MbtM; AltName: Full=Fatty acyl-[acyl-carrier-protein] synthetase; Short=Fatty acyl-ACP synthetase; AltName: Full=Mycobactin synthetase protein M gi|41396005|gb|AAS03871.1| FadD33_2 [Mycobacterium avium subsp. paratuberculosis K-10] Length=521 Score = 711 bits (1835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/526 (70%), Positives = 420/526 (80%), Gaps = 10/526 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MSELAA LT +M+ DL+V DRE++ W RH WPEVHGLAE +AAWLLD DRPAA+GLV Sbjct 1 MSELAAALTAAMRTGGSDLVVFDRESAAWRRHRWPEVHGLAEGIAAWLLDRDRPAALGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT+E VAAI GAWLAGA VSILPGPVRGA +RWAD TLTRF GIGVRTVLS GS+L Sbjct 61 GEPTLEFVAAIVGAWLAGAGVSILPGPVRGAEGRRWADTTLTRFAGIGVRTVLSHGSHLD 120 Query 121 RLRSVDTA---GVTIGDLSTAAHTNRSAT--PVASEGPAVLQGTAGSTGAPRTAILSPGA 175 L+++D + + + DL+ AA+T R P PA+LQGTAGSTG P+TA LSP A Sbjct 121 ALQALDPSRPDEMVVEDLAVAANTGRRCPEPPAPHANPAILQGTAGSTGTPKTAALSPDA 180 Query 176 VLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFR 235 VL+NLRGLN R+G A DVGCSWLPLYHDMGL+F+L++AL G LWLAPT+AFTASPFR Sbjct 181 VLANLRGLNARLGVTPA-DVGCSWLPLYHDMGLSFLLASALGGMSLWLAPTSAFTASPFR 239 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAM 295 WL+WLS+S AT+TAAPNFAYNL+GKYARRVS VDLGALRV +NGGEPVDC G RF AM Sbjct 240 WLAWLSESRATITAAPNFAYNLVGKYARRVSGVDLGALRVAINGGEPVDCAGFERFTTAM 299 Query 296 APFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRI 355 APFGFDAGA PSYGLAE+TCAV+VP PG GL V D +G +HAVLG PIPG E+RI Sbjct 300 APFGFDAGAATPSYGLAEATCAVSVPAPGTGLRFADVSDETGTRRHAVLGAPIPGTEIRI 359 Query 356 SCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAK 415 S +A IGEIEIRGASMM GYLG PID +WF TGDLG+ GLVVCGRAK Sbjct 360 S----PRHDAPDGIGEIEIRGASMMDGYLGHAPIDHQNWFPTGDLGFFSDDGLVVCGRAK 415 Query 416 EVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARA 475 E+I++AGRNIFPTE+E VAAQV GVREGAVVALGTG+ S RPGL++AAEF G D A ARA Sbjct 416 ELITLAGRNIFPTEIETVAAQVPGVREGAVVALGTGENSARPGLIIAAEFAGRDRAGARA 475 Query 476 ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 E+IQRVAS CG+VPSDV+F++PGSLPRTSSGKLRRL VRRSLE D Sbjct 476 EVIQRVASVCGVVPSDVIFMAPGSLPRTSSGKLRRLDVRRSLEAVD 521 >gi|333990172|ref|YP_004522786.1| polyketide synthase Pks16 [Mycobacterium sp. JDM601] gi|333486140|gb|AEF35532.1| polyketide synthase Pks16 [Mycobacterium sp. JDM601] Length=527 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/528 (66%), Positives = 401/528 (76%), Gaps = 12/528 (2%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MS LA LTR+M AS DL+V D+ + W RHPW +VH A+ VA+ +LD R AVGLV Sbjct 1 MSVLAGALTRAMTASDEDLVVFDQASGSWQRHPWAQVHARAQGVASRILDTGRTGAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVELVAAIQGAWLAG +VSILPGPVRG++ Q+WA AT RF GIGV TV + G Sbjct 61 GEPTVELVAAIQGAWLAGRSVSILPGPVRGSDPQQWAQATRNRFSGIGVDTVFTHGGPRQ 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSA-TPV--ASEGPAVLQGTAGSTGAPRTAILSPGAVL 177 L TA + + D++ AA +A TPV A + PAVLQGTAGSTG PRTA LSP AVL Sbjct 121 LLDEAGTA-IAVYDVTAAATEPSTAFTPVTAAPDVPAVLQGTAGSTGTPRTAQLSPAAVL 179 Query 178 SNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWL 237 +N+ GL + VG D ATDVGCSWLPLYHDMGL F+LSAAL G+ LWLAPT AF ASPFRWL Sbjct 180 ANVSGLAEHVGVDPATDVGCSWLPLYHDMGLTFLLSAALTGSALWLAPTAAFAASPFRWL 239 Query 238 SWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAP 297 SWL DS ATMTAAPNFAY +IGKYARRV EVDLG LRV +NGGEPVDC GL RF + Sbjct 240 SWLHDSRATMTAAPNFAYGVIGKYARRVPEVDLGRLRVAINGGEPVDCAGLERFVAELGR 299 Query 298 FGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI-----DGSGAHKHAVLGNPIPGME 352 +G GA++PSYGLAE+TCAVT P PG GL D I D +HAVLG PIPGM+ Sbjct 300 YGLAPGALMPSYGLAEATCAVTAPQPGTGLQYDETIGAASDDAPAVRRHAVLGEPIPGMQ 359 Query 353 VRIS-CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVC 411 VRIS ++ + RE+GEIEIRG SMM+GY+ Q +DP WFATGDLGY GLVVC Sbjct 360 VRISPVAERHEELSQREVGEIEIRGTSMMSGYVDQPALDPAGWFATGDLGYFTDAGLVVC 419 Query 412 GRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEA 471 GRAKE+ISIAGRN+FPTE+E VAA+VRGVR+GAVVA+GT R GLV+AAEFRG DEA Sbjct 420 GRAKEIISIAGRNVFPTEIERVAAEVRGVRDGAVVAVGTA--GIRAGLVIAAEFRGRDEA 477 Query 472 NARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEM 519 ARA++I RVAS+CG+VP+DVVF++PGSLPRTSSGKLRRL V+R+LE+ Sbjct 478 GARADVISRVASQCGVVPADVVFLAPGSLPRTSSGKLRRLEVKRNLEV 525 >gi|118473699|ref|YP_886489.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium smegmatis str. MC2 155] gi|118174986|gb|ABK75882.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155] Length=526 Score = 644 bits (1661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/527 (63%), Positives = 405/527 (77%), Gaps = 14/527 (2%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ L+A LT +M S+ DL+V + ET W RHPW +VH A++VA + D +AVG+V Sbjct 1 MNVLSAALTEAMTTSSADLVVFEPETRTWHRHPWGQVHLRAQNVAE-RIGQDGSSAVGIV 59 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVE VAAI GA LAG+AVSILPG VRGA+ +WAD+TL RF IGV TV S GSYL Sbjct 60 GEPTVEGVAAILGALLAGSAVSILPGLVRGADPDQWADSTLNRFANIGVTTVFSHGSYLE 119 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSAT-----PVASEGPAVLQGTAGSTGAPRTAILSPGA 175 +LR+ D++ + I D + AH RS T P+ AVLQGTAGSTG PRTA L P A Sbjct 120 QLRTRDSS-LVIHDDAEVAHAQRSTTLELGAPLGEF--AVLQGTAGSTGTPRTAQLRPDA 176 Query 176 VLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFR 235 VL+NLRGL +RVG A +D+GCSWLPLYHDMGL F+LSAA+ G W APTTAF ++PF Sbjct 177 VLANLRGLAERVGL-AGSDIGCSWLPLYHDMGLTFLLSAAVGGTETWQAPTTAFASAPFS 235 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAM 295 W+ WL++S AT+TAAPN AY LIGKY+RR+++VDL A+R LNGGEPVD DG RF + Sbjct 236 WVHWLTESRATLTAAPNMAYGLIGKYSRRLTDVDLSAMRFALNGGEPVDIDGTARFGTEL 295 Query 296 APFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI----DGSGAHKHAVLGNPIPGM 351 + FGFD GA+ PSYGLAES+CAVTVPVPG+GL D + GS K AVLG+ I GM Sbjct 296 SRFGFDPGALSPSYGLAESSCAVTVPVPGVGLKVDEITVTTEAGSSTQKLAVLGHAIAGM 355 Query 352 EVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVC 411 EVR+ GD+ AG RE+GE+EIRG SMM+GY G+ P+DP +WF TGDLGYL GLV+C Sbjct 356 EVRLQPGDEDAGVVDREVGEVEIRGTSMMSGYRGEAPLDPGEWFPTGDLGYLTDDGLVIC 415 Query 412 GRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEA 471 GR KE+I++AGRNIFPTE+E +AA+V+GVREGAVVA+GT +R+ RPGLV+AAEFRGPDEA Sbjct 416 GRKKELITVAGRNIFPTEIERIAARVKGVREGAVVAVGTNERAVRPGLVIAAEFRGPDEA 475 Query 472 NARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 AR+E++QRVASECG+VP+DVVF++PGSLPRTSSGKLRRL V+R LE Sbjct 476 GARSEVVQRVASECGVVPADVVFLAPGSLPRTSSGKLRRLEVKRQLE 522 >gi|120402942|ref|YP_952771.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium vanbaalenii PYR-1] gi|119955760|gb|ABM12765.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=526 Score = 636 bits (1641), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 327/526 (63%), Positives = 398/526 (76%), Gaps = 8/526 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MS LA ++ +M AS +L++LDR + W RHPW EVH AE++A +LD AVGLV Sbjct 1 MSVLATAVSHAMTASLRELVLLDRASGQWSRHPWQEVHARAENIAERVLDGP-DGAVGLV 59 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVE VAAIQGAWLAG AVSILPGPVRGA+D++WA +T+ RF GIGV LS G++L Sbjct 60 GEPTVEFVAAIQGAWLAGRAVSILPGPVRGADDRQWAMSTVERFAGIGVSQALSYGNHL- 118 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSAT----PVASEGPAVLQGTAGSTGAPRTAILSPGAV 176 L + + + + D++ HT RS T + PAVLQGTAGSTG PRTA+LSP AV Sbjct 119 ELLGANGSRLQVHDVTAVGHTRRSTTLSPQAAPAGAPAVLQGTAGSTGTPRTALLSPEAV 178 Query 177 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW 236 L+N+ L Q TD DVG +WLPLYHDMGL F+L+ L GA +WLAPT AF ASPFRW Sbjct 179 LNNVSALWQHTSTDPDRDVGMTWLPLYHDMGLTFLLTGFLTGAEMWLAPTAAFAASPFRW 238 Query 237 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA 296 L+WLSDS A++TAAPNFAY++IG+YARRVS+VDLG LR +NGGEPVDC+G F + +A Sbjct 239 LTWLSDSRASLTAAPNFAYSVIGRYARRVSDVDLGRLRFAINGGEPVDCEGFQLFLDELA 298 Query 297 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVID--GSGAHKHAVLGNPIPGMEVR 354 FG D A PSYGLAESTCAVT P PG GL+ + + D +HAVLG PIPGM+VR Sbjct 299 RFGLDPRAAAPSYGLAESTCAVTTPEPGTGLVVESITDPATDAVQRHAVLGRPIPGMDVR 358 Query 355 ISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRA 414 IS + + IGE+EIRG SMM+GYLGQ P++P +WF TGDLGYL GLVVCGR Sbjct 359 ISESEHSRKVGDHTIGELEIRGTSMMSGYLGQDPLEPGEWFRTGDLGYLTDDGLVVCGRV 418 Query 415 KEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANAR 474 KE+I++AGRNIFP+EVE VAAQVRGVREGAVVA+GT S R GL+VAAEFRGPDEA AR Sbjct 419 KELITVAGRNIFPSEVERVAAQVRGVREGAVVAVGTDGNSARQGLIVAAEFRGPDEAGAR 478 Query 475 AELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMA 520 +E++QRVAS+CG+VP+DVVF++PGSLPRTSSGKLRRL V+++LE A Sbjct 479 SEVVQRVASQCGVVPADVVFLAPGSLPRTSSGKLRRLEVKQNLEAA 524 >gi|315445358|ref|YP_004078237.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|315263661|gb|ADU00403.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=528 Score = 622 bits (1605), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 323/525 (62%), Positives = 388/525 (74%), Gaps = 11/525 (2%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MS LA L+ +M AS DL++LDR + LW RHPW E+H AE++A +L+ DR AVGLV Sbjct 1 MSVLATALSEAMTASTRDLVLLDRASGLWVRHPWQELHTRAENIAEHILN-DRDGAVGLV 59 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT ELV+AIQG WLAG ++ILPGP+RGA+++ WA AT RF GIGV +L+ G +L Sbjct 60 GEPTAELVSAIQGTWLAGRTLAILPGPIRGADEREWAAATAQRFAGIGVGQILTYGEHLE 119 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSAT----PVASEGPAVLQGTAGSTGAPRTAILSPGAV 176 LR D G+T+ DL+ H RS T P A PAVLQGTAGSTG PRTA+LSP A+ Sbjct 120 LLRPNDF-GITVHDLAVVGHAQRSTTLASAPAAPGTPAVLQGTAGSTGTPRTALLSPDAL 178 Query 177 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW 236 N+ G+ + D D G +WLPLYHDMGL F+L+ ++G+ +WLAPT +F ASPFRW Sbjct 179 KHNVAGMLRHTDVDPGRDRGLTWLPLYHDMGLTFLLTGFMSGSEMWLAPTASFAASPFRW 238 Query 237 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA 296 L+WLS+S A +TAAPNFAY++IGKYARRV +VDL LR LNGGEPVDCDG F +A Sbjct 239 LTWLSESRAGLTAAPNFAYSVIGKYARRVPDVDLSDLRFALNGGEPVDCDGFGLFLRELA 298 Query 297 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI--DGSGAHKHAVLGNPIPGMEVR 354 FG D G PSYGLAESTCAVT P PG GLL D + D +HAVLG PIPGME+R Sbjct 299 RFGLDPGVAAPSYGLAESTCAVTSPRPGTGLLVDEITDPDTDTRRRHAVLGEPIPGMELR 358 Query 355 IS-CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGR 413 I D +G SREIGEIEIRG SMM+GYLG +P+ P WF TGDLGYL GLVVCGR Sbjct 359 IGPSADSRSG--SREIGEIEIRGTSMMSGYLGAEPLAPGQWFPTGDLGYLTDRGLVVCGR 416 Query 414 AKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANA 473 KE+I+IAGRNIFPTEVE VAA VRGVREGAVVA+ T S R GLV+AAEFRG DE+ A Sbjct 417 VKELITIAGRNIFPTEVERVAAGVRGVREGAVVAVSTDSGSARQGLVIAAEFRGADESGA 476 Query 474 RAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 ++E++QRVAS+CG+VPS+VVF+ PGSLPRTSSGKLRRLAV+ L+ Sbjct 477 KSEVVQRVASQCGVVPSEVVFLKPGSLPRTSSGKLRRLAVKNDLD 521 >gi|145224990|ref|YP_001135668.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium gilvum PYR-GCK] gi|145217476|gb|ABP46880.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] Length=528 Score = 622 bits (1604), Expect = 4e-176, Method: Compositional matrix adjust. Identities = 318/524 (61%), Positives = 389/524 (75%), Gaps = 9/524 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MS LA L+ +M AS DL++LDR + W RHPW E+H AE++A +L+ DR AVGLV Sbjct 1 MSVLATALSEAMTASTRDLVLLDRASGQWVRHPWQELHTRAENIAEHILN-DRDGAVGLV 59 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT ELV+AIQG WLAG A++ILPGP+RGA+++ WA AT RF GIGV +L+ G +L Sbjct 60 GEPTAELVSAIQGTWLAGRALAILPGPIRGADEREWAAATAQRFAGIGVGQILTYGEHLE 119 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSAT----PVASEGPAVLQGTAGSTGAPRTAILSPGAV 176 LR + G+T+ DL+ H RS T P A PAVLQGTAGSTG PRTA+LS AV Sbjct 120 LLRP-NVFGITVHDLAVVGHAQRSTTLVSAPAAPGTPAVLQGTAGSTGTPRTALLSQDAV 178 Query 177 LSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRW 236 N+ G+ + D D G +WLPLYHDMGL F+L+ ++G+ +WLAPT +F ASPFRW Sbjct 179 KHNVAGMLRHTDVDPGRDRGLTWLPLYHDMGLTFLLTGFMSGSEMWLAPTASFAASPFRW 238 Query 237 LSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMA 296 L+WLS+S A +TAAPNFAY++IGKYARRV +VDL LR LNGGEPVDCDG F ++ Sbjct 239 LAWLSESRAGLTAAPNFAYSVIGKYARRVPDVDLSNLRFALNGGEPVDCDGFELFLRELS 298 Query 297 PFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGA--HKHAVLGNPIPGMEVR 354 FG D G PSYGLAESTCAVT P PG GLL D + D +HAVLG PIPGME+R Sbjct 299 RFGLDPGVAAPSYGLAESTCAVTSPRPGTGLLVDDITDPDTGTPRRHAVLGEPIPGMELR 358 Query 355 ISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRA 414 I+ + + REIGE+EIRG SMM+GYLG++P+ P WF TGDLGYL GLVVCGR Sbjct 359 IAP-SEGRRSGEREIGEVEIRGTSMMSGYLGEEPLAPGQWFPTGDLGYLTDAGLVVCGRV 417 Query 415 KEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANAR 474 KE+I+IAGRNIFPTEVE VAA+VRGVREGAVVA+GT S R GLV+AAEFRG DE+ A+ Sbjct 418 KELITIAGRNIFPTEVERVAAEVRGVREGAVVAVGTDSGSARQGLVIAAEFRGADESGAK 477 Query 475 AELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 +E++QRVAS+CG+VPS+VVF+ PGSLPRTSSGKLRRLAV+ L+ Sbjct 478 SEVVQRVASQCGVVPSEVVFLKPGSLPRTSSGKLRRLAVKNDLD 521 >gi|108799309|ref|YP_639506.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. MCS] gi|119868425|ref|YP_938377.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. KMS] gi|126434967|ref|YP_001070658.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. JLS] gi|108769728|gb|ABG08450.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119694514|gb|ABL91587.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] gi|126234767|gb|ABN98167.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=535 Score = 621 bits (1601), Expect = 1e-175, Method: Compositional matrix adjust. Identities = 330/523 (64%), Positives = 397/523 (76%), Gaps = 11/523 (2%) Query 4 LAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEP 63 LA+ L+ SM A+ DL++LDRE+ W RHPW EV + +VA + D D +AVG++GEP Sbjct 8 LASALSDSMAAADTDLVLLDRESGAWRRHPWSEVLARSMNVAERIGDAD-ASAVGVIGEP 66 Query 64 TVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLR 123 VE VAAI G++LAG VS+LPGPVRGA +WA TL RF G GV VL+ GS+L LR Sbjct 67 NVEFVAAIVGSFLAGRGVSVLPGPVRGAAADQWAHNTLARFAGAGVSHVLTHGSHLGHLR 126 Query 124 SVDTAGVTIGDLSTAAHTNRSATPVASEGP----AVLQGTAGSTGAPRTAILSPGAVLSN 179 D + + D++T A NRSA P+ + P A+LQGTAGSTG PRT LSP AVL+N Sbjct 127 VADGS-AAVHDVTTWAGPNRSA-PLDASLPTGDVAILQGTAGSTGTPRTVRLSPDAVLAN 184 Query 180 LRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSW 239 L GL+ R+G + DVGCSWLPLYHDMGL+F+L+ ALAG W APT+AF ASPFRWL+W Sbjct 185 LTGLSARIGLERGHDVGCSWLPLYHDMGLSFLLTGALAGVETWQAPTSAFQASPFRWLNW 244 Query 240 LSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFG 299 LSDS AT+TAAPN A+ +IGKYARRV++VDL +R LNGGEPVDC+ FA AM+ FG Sbjct 245 LSDSRATITAAPNMAFGMIGKYARRVTDVDLSNVRFALNGGEPVDCELTALFATAMSRFG 304 Query 300 FDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI----DGSGAHKHAVLGNPIPGMEVRI 355 F AGA+ PSYGLAESTCAVTVP PG GL D V DG +HAVLG+ IPGM+VRI Sbjct 305 FSAGALAPSYGLAESTCAVTVPEPGDGLRTDEVAVGTDDGVSLRRHAVLGHAIPGMQVRI 364 Query 356 SCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAK 415 S + A + RE+GE+EIRG+SMM+GY+G +D WFATGDLGYL G LVVCGRAK Sbjct 365 SPREGDADVSGREVGEVEIRGSSMMSGYVGGASLDAQTWFATGDLGYLVDGALVVCGRAK 424 Query 416 EVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARA 475 E+I++AGRNIFP E+E VAAQV GVREGAVVA+GTG+ S RPGLV+AAEFRG DEA AR+ Sbjct 425 ELITVAGRNIFPAEIERVAAQVPGVREGAVVAVGTGEGSIRPGLVIAAEFRGRDEAGARS 484 Query 476 ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 EL+Q+VAS+CG+VPSDVVFV PGSLPRTSSGKLRRLAV+ SLE Sbjct 485 ELVQQVASQCGVVPSDVVFVRPGSLPRTSSGKLRRLAVKHSLE 527 >gi|336462100|gb|EGO40942.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium avium subsp. paratuberculosis S397] Length=518 Score = 595 bits (1535), Expect = 4e-168, Method: Compositional matrix adjust. Identities = 311/520 (60%), Positives = 383/520 (74%), Gaps = 7/520 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ LAA + +M S DL+VLD+++ W PWPEVHG+AES+AA LL DR AVGLV Sbjct 1 MNALAAAMRDAMTRSPHDLVVLDKDSDTWRSCPWPEVHGMAESIAARLLQRDRLGAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVEL+AAIQGAWLAG AVS+LP P RGA+ WA +TL RF GIGV TVLS G L Sbjct 61 GEPTVELIAAIQGAWLAGVAVSLLPRPRRGADPSEWAHSTLQRFGGIGVDTVLSHGGVLR 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASE--GPAVLQGTAGSTGAPRTAILSPGAVLS 178 L + D+A V++ DL+ AA T S + G A+LQGTAGSTG PRTA+LSP AVLS Sbjct 121 TLAAADSA-VSVCDLAQAARTPTSTGLEYQDDSGVAILQGTAGSTGNPRTAVLSPAAVLS 179 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLS 238 N+RGL +R+ D A+D CSWLPLYHDMGLAF+L++AL+G PLW APT AF+A+P RW Sbjct 180 NMRGLIERLRLDGASDRACSWLPLYHDMGLAFLLTSALSGMPLWQAPTGAFSAAPLRWAE 239 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPF 298 WLSDS AT TA PNF Y++IG+Y+ RV +VDLGALR+ +NGGEPVDC+G RFA AMAPF Sbjct 240 WLSDSQATFTAGPNFGYSMIGRYSGRVRDVDLGALRIAINGGEPVDCEGFQRFATAMAPF 299 Query 299 GFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCG 358 GF A A P+YG+AE+TCAVT+P G GL D + ++A+LG PI GME+RI+ Sbjct 300 GFRAAAATPAYGMAEATCAVTMPGCGEGLQIDERTESGVRQRYALLGGPIAGMELRIAAT 359 Query 359 DQAAGNASREIGEIEIRGASMMAGYLGQQPIDPD-DWFATGDLGYLGAGGLVVCGRAKEV 417 D+ +G +GE+EIRG+SMM GYLG D DWF TGD+GYL G LV+CGR+KEV Sbjct 360 DEPSGEG---VGEVEIRGSSMMTGYLGDTTGRSDGDWFPTGDIGYLVDGALVICGRSKEV 416 Query 418 ISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAEL 477 I++AGRNIFPTE+E VAAQV GVR G VVA+G+ + + L++AAEF G D R+ + Sbjct 417 ITVAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGADRDVTRSAV 476 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSL 517 I+RV S CG+ P+DVV + PGSLPRTSSGKLRRL VRR L Sbjct 477 IKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRRQL 516 >gi|41406124|ref|NP_958960.1| acyl-CoA synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394472|gb|AAS02343.1| FadD33_1 [Mycobacterium avium subsp. paratuberculosis K-10] Length=518 Score = 593 bits (1528), Expect = 3e-167, Method: Compositional matrix adjust. Identities = 310/520 (60%), Positives = 382/520 (74%), Gaps = 7/520 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ LAA + +M S DL+VLD+++ W PWPEVHG+AES+AA LL DR AVGLV Sbjct 1 MNALAAAMRDAMTRSPHDLVVLDKDSDTWRSCPWPEVHGMAESIAARLLQRDRLGAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVEL+AAIQGAWLAG AVS+LP P RGA+ WA +TL RF GIGV TVLS G L Sbjct 61 GEPTVELIAAIQGAWLAGVAVSLLPRPRRGADPSEWAHSTLQRFGGIGVDTVLSHGGVLR 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASE--GPAVLQGTAGSTGAPRTAILSPGAVLS 178 L + D+A V++ DL+ AA T S + G A+LQGTAGSTG PRTA+LSP AVLS Sbjct 121 TLAAADSA-VSVCDLAQAARTPTSTGLEYQDDSGVAILQGTAGSTGNPRTAVLSPAAVLS 179 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLS 238 N+RGL +R+ D A+D CSWLPLYHDMGLAF+L++AL+G PLW APT AF+A+P RW Sbjct 180 NMRGLIERLRLDGASDRACSWLPLYHDMGLAFLLTSALSGMPLWQAPTGAFSAAPLRWAE 239 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPF 298 WLSDS AT TA PNF Y++IG+Y+ RV +VDLGALR+ +NGGEPVDC+G RFA AMAPF Sbjct 240 WLSDSQATFTAGPNFGYSMIGRYSGRVRDVDLGALRIAINGGEPVDCEGFQRFATAMAPF 299 Query 299 GFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCG 358 GF A A P+YG+AE+TCAVT+P G GL D + ++A+LG PI GME+RI+ Sbjct 300 GFRAAAATPAYGMAEATCAVTMPGCGEGLQIDERTESGVRQRYALLGGPIAGMELRIAAT 359 Query 359 DQAAGNASREIGEIEIRGASMMAGYLGQQPIDPD-DWFATGDLGYLGAGGLVVCGRAKEV 417 D+ +G +GE+EIRG+S M GYLG D DWF TGD+GYL G LV+CGR+KEV Sbjct 360 DEPSGEG---VGEVEIRGSSTMTGYLGDTTGRSDGDWFPTGDIGYLVDGALVICGRSKEV 416 Query 418 ISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAEL 477 I++AGRNIFPTE+E VAAQV GVR G VVA+G+ + + L++AAEF G D R+ + Sbjct 417 ITVAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGADRDVTRSAV 476 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSL 517 I+RV S CG+ P+DVV + PGSLPRTSSGKLRRL VRR L Sbjct 477 IKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRRQL 516 >gi|118462530|ref|YP_879330.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium avium 104] gi|118163817|gb|ABK64714.1| acyl-CoA synthase [Mycobacterium avium 104] Length=518 Score = 590 bits (1522), Expect = 1e-166, Method: Compositional matrix adjust. Identities = 308/520 (60%), Positives = 380/520 (74%), Gaps = 7/520 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ LAA + +M S DL+VLD+++ W PWPEVHG+AES+A LL DR AVGLV Sbjct 1 MNVLAAAMRDAMTRSPHDLVVLDKDSDTWRSCPWPEVHGMAESIAVRLLQRDRLGAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVEL+AAIQGAWLAG AVS+LP P RGA+ WA +TL RF GIGV TVLS G L Sbjct 61 GEPTVELIAAIQGAWLAGVAVSLLPRPRRGADPSEWAHSTLQRFGGIGVDTVLSHGGVLR 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPVASE--GPAVLQGTAGSTGAPRTAILSPGAVLS 178 L + D+A V++ DL+ AA T S + G A+LQGTAGSTG PRTA+LSP AVLS Sbjct 121 TLAAADSA-VSVCDLAQAARTPTSTGLEYQDDSGVAILQGTAGSTGNPRTAVLSPAAVLS 179 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLS 238 N+RGL +R+ D A+D CSWLPLYHDMGLAF+L++ L+G PLW APT AF+A+P RW Sbjct 180 NMRGLIERLRLDGASDRACSWLPLYHDMGLAFLLTSVLSGMPLWQAPTGAFSAAPLRWAE 239 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPF 298 WLSDS AT TA PNF Y++IG+YA RV +VDLGALR+ +NGGEPVDC+G RFA AMAPF Sbjct 240 WLSDSQATFTAGPNFGYSMIGRYAGRVRDVDLGALRIAINGGEPVDCEGFQRFAMAMAPF 299 Query 299 GFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCG 358 GF A A P+YG+AE+TCAVT+P G GL D + ++A+LG PI GM++RI+ Sbjct 300 GFRASAATPAYGMAEATCAVTMPSCGEGLQIDERTESGVPQRYALLGRPIAGMQLRIAAT 359 Query 359 DQAAGNASREIGEIEIRGASMMAGYLGQQPIDPD-DWFATGDLGYLGAGGLVVCGRAKEV 417 D+ +G +GE+EI G+SMM GYLG D DWF TGD+GYL G LV+CGR+KEV Sbjct 360 DEPSGEG---VGEVEIHGSSMMTGYLGDTTGRSDGDWFPTGDIGYLVDGALVICGRSKEV 416 Query 418 ISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAEL 477 I++AGRNIFPTE+E VAAQV GVR G VVA+G+ + + L++AAEF G D R+ + Sbjct 417 ITVAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGADRDVTRSAV 476 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSL 517 I+RV S CG+ P+DVV + PGSLPRTSSGKLRRL VRR L Sbjct 477 IKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRRQL 516 >gi|119867809|ref|YP_937761.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. KMS] gi|119693898|gb|ABL90971.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] Length=524 Score = 588 bits (1516), Expect = 7e-166, Method: Compositional matrix adjust. Identities = 319/528 (61%), Positives = 381/528 (73%), Gaps = 18/528 (3%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ LA+ L +M +S DL+VLD W RHPW EVH AE++AA + + D V LV Sbjct 1 MNPLASALADAMTSSGRDLVVLDH--GGWRRHPWAEVHQRAENIAARITE-DAATVVVLV 57 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVE +AAI G AGAA+SILPGPVRGA+ +WA T+ R IGVR V S G +L Sbjct 58 GEPTVEFIAAIPGTLYAGAALSILPGPVRGADLGQWARNTMQRCASIGVRLVFSHGEHLD 117 Query 121 RLRSVDTAGVTIGDLSTAAHTNR--SATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLS 178 LR+ A + D++ H R S TP AVLQGTAGSTG PRTA LSP AVL+ Sbjct 118 ALRAT-PASIPTCDVTETGHARRDSSFTPPDHGEFAVLQGTAGSTGIPRTAQLSPEAVLA 176 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLS 238 NLRGL + A D GCSWLPLYHDMGLAF+L+ AL GA LW APTTAF+ASPF WL Sbjct 177 NLRGLVACIDITPA-DTGCSWLPLYHDMGLAFLLTNALGGAELWQAPTTAFSASPFSWLQ 235 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPF 298 W+++S AT+TAAPN AY LIGKY R+++ DLGALR LNGGEPVDC G RFA MA F Sbjct 236 WMTESTATLTAAPNMAYGLIGKYGSRLTDFDLGALRFALNGGEPVDCQGYRRFATEMARF 295 Query 299 GFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI----DGSGAHKHAVLGNPIPGMEVR 354 G D A++P+YGLAES+CAVTVP+ G GL D V DG HAV+G PIPGM+VR Sbjct 296 GLDPSALVPAYGLAESSCAVTVPILGSGLQVDEVQVSSDDGRFIRTHAVVGEPIPGMQVR 355 Query 355 IS----CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVV 410 I+ G+Q G R+ GEIE+RG S+M+GYLG+ P++ WF TGDLGY GLVV Sbjct 356 IAPTDGSGEQVDG---RDFGEIEVRGTSLMSGYLGEPPLEAGSWFPTGDLGYFVDSGLVV 412 Query 411 CGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDE 470 CGRAKE+I++AGRNIFP EVE VAAQV+GVREGAVVA+GT + + RPGLV+AAEFRG DE Sbjct 413 CGRAKELITVAGRNIFPAEVERVAAQVQGVREGAVVAVGTDESAVRPGLVIAAEFRGTDE 472 Query 471 ANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 AR EL+QRVASECG+VPS+VVF+ PG+LPRTSSGKLRRL V+RS+E Sbjct 473 PAARTELVQRVASECGVVPSNVVFLEPGALPRTSSGKLRRLEVKRSME 520 >gi|108798691|ref|YP_638888.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. MCS] gi|126434292|ref|YP_001069983.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium sp. JLS] gi|123179087|sp|Q1BBA2.1|MBTM_MYCSS RecName: Full=Long-chain-fatty-acid--[acyl-carrier-protein] ligase MbtM; AltName: Full=Fatty acyl-[acyl-carrier-protein] synthetase; Short=Fatty acyl-ACP synthetase; AltName: Full=Mycobactin synthetase protein M gi|108769110|gb|ABG07832.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|126234092|gb|ABN97492.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=521 Score = 586 bits (1510), Expect = 4e-165, Method: Compositional matrix adjust. Identities = 317/525 (61%), Positives = 379/525 (73%), Gaps = 18/525 (3%) Query 4 LAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEP 63 +A+ L +M +S DL+VLD W RHPW EVH AE++AA + + D V LVGEP Sbjct 1 MASALADAMTSSGRDLVVLDH--GGWRRHPWAEVHQRAENIAARITE-DAATVVVLVGEP 57 Query 64 TVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLR 123 TVE +AAI G AGAA+SILPGPVRGA+ +WA T+ R IGVR V S G +L LR Sbjct 58 TVEFIAAIPGTLYAGAALSILPGPVRGADLGQWARNTMQRCASIGVRLVFSHGEHLDALR 117 Query 124 SVDTAGVTIGDLSTAAHTNR--SATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLR 181 + A + D++ H R S TP AVLQGTAGSTG PRTA LSP AVL+NLR Sbjct 118 AT-PASIPTCDVTETGHARRDSSFTPPDHGEFAVLQGTAGSTGIPRTAQLSPEAVLANLR 176 Query 182 GLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLS 241 GL + A D GCSWLPLYHDMGLAF+L+ AL GA LW APTTAF+ASPF WL W++ Sbjct 177 GLVACIDITPA-DTGCSWLPLYHDMGLAFLLTNALGGAELWQAPTTAFSASPFSWLQWMT 235 Query 242 DSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFD 301 +S AT+TAAPN AY LIGKY R+++ DLGALR LNGGEPVDC G RFA MA FG D Sbjct 236 ESTATLTAAPNMAYGLIGKYGSRLTDFDLGALRFALNGGEPVDCQGYRRFATEMARFGLD 295 Query 302 AGAVLPSYGLAESTCAVTVPVPGIGLLADRVI----DGSGAHKHAVLGNPIPGMEVRIS- 356 A++P+YGLAES+CAVTVP+ G GL D V DG HAV+G PIPGM+VRI+ Sbjct 296 PSALVPAYGLAESSCAVTVPILGSGLQVDEVQVSSDDGRFIRTHAVVGEPIPGMQVRIAP 355 Query 357 ---CGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGR 413 G+Q G R+ GEIE+RG S+M+GYLG+ P++ WF TGDLGY GLVVCGR Sbjct 356 TDGSGEQVDG---RDFGEIEVRGTSLMSGYLGEPPLEAGSWFPTGDLGYFVDSGLVVCGR 412 Query 414 AKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANA 473 AKE+I++AGRNIFP EVE VAAQV+GVREGAVVA+GT + + RPGLV+AAEFRG DE A Sbjct 413 AKELITVAGRNIFPAEVERVAAQVQGVREGAVVAVGTDESAVRPGLVIAAEFRGTDEPAA 472 Query 474 RAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 R EL+QRVASECG+VPS+VVF+ PG+LPRTSSGKLRRL V+RS+E Sbjct 473 RTELVQRVASECGVVPSNVVFLEPGALPRTSSGKLRRLEVKRSME 517 >gi|254819093|ref|ZP_05224094.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium intracellulare ATCC 13950] Length=519 Score = 575 bits (1483), Expect = 5e-162, Method: Compositional matrix adjust. Identities = 299/523 (58%), Positives = 376/523 (72%), Gaps = 10/523 (1%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 M+ LAA + +M S DL+VLD++T W PWPEVHG+AES+A LL D AVG+V Sbjct 1 MNVLAAAMRDAMTRSPHDLVVLDKDTDKWTARPWPEVHGMAESIATHLLQQDHLGAVGIV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPTVELVAAIQGAWLAGAAVSILP P RGA+ WA +TL+RF GIGV TV S G+ L Sbjct 61 GEPTVELVAAIQGAWLAGAAVSILPRPRRGADPAEWAHSTLSRFRGIGVSTVFSHGATLR 120 Query 121 RLRSVDTAGVTIGDLSTAAHT--NRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLS 178 L ++ +++ L+ AA T + + A+LQGTAGSTG PRTA+LSP AVL+ Sbjct 121 TLGDAEST-LSVSSLAEAARTPASNDLQSHSDSNAAILQGTAGSTGDPRTAVLSPEAVLN 179 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLS 238 N+RGL +R+ D +D CSWLP+YHDMGLAF+L+A L+G PLW APT AF+A+P RW Sbjct 180 NMRGLIERLQLDG-SDRACSWLPIYHDMGLAFLLTAVLSGMPLWQAPTGAFSAAPLRWAD 238 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPF 298 WLS S AT TA PNF Y+++G+Y+ RVS+VDLGALR+ +NGGEPVDC+G RFA+AMAPF Sbjct 239 WLSASAATFTAGPNFGYSMLGRYSGRVSDVDLGALRIAINGGEPVDCEGFQRFADAMAPF 298 Query 299 GFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCG 358 G A A P+YG+AESTCAVT+P G GL D + ++A+LG PIPGME+RIS Sbjct 299 GLRASAATPAYGMAESTCAVTMPACGQGLRIDERTESDVRQRYALLGPPIPGMELRISPT 358 Query 359 DQAAGNASREIGEIEIRGASMMAGYLGQQPIDPD---DWFATGDLGYLGAGGLVVCGRAK 415 ++A + +GE+EIRG+SMM Y G D +WF TGD+GYL G LV+CGR+K Sbjct 359 HRSADDG---VGEVEIRGSSMMTKYFGDPATGSDRGAEWFRTGDIGYLVDGELVICGRSK 415 Query 416 EVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARA 475 EVI+IAGRNIFPTE+E VAAQV GVR G VVA+G+ + + L++AAEF G D R+ Sbjct 416 EVITIAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGSDHDVTRS 475 Query 476 ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 +I+RV S CG+ P+DVV + PGSLPRTSSGKLRRL VR L+ Sbjct 476 AVIKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRSQLQ 518 >gi|342860256|ref|ZP_08716908.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium colombiense CECT 3035] gi|342132634|gb|EGT85863.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium colombiense CECT 3035] Length=518 Score = 574 bits (1479), Expect = 2e-161, Method: Compositional matrix adjust. Identities = 306/523 (59%), Positives = 369/523 (71%), Gaps = 13/523 (2%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLV 60 MS LAA + +M S DL+VLD+ET W PWPEVHG+AE +AA LL D AVGLV Sbjct 1 MSVLAAAMREAMTRSPHDLVVLDKETDQWTARPWPEVHGMAERIAARLLQQDHVGAVGLV 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 GEPT+EL+AAIQGAWLAGAAVSILP P RGA+ WA T+TRF GIGV VLS G L Sbjct 61 GEPTIELIAAIQGAWLAGAAVSILPRPRRGADPADWAHNTMTRFSGIGVSMVLSHGETLR 120 Query 121 RLRSVDTAGVTIGDLSTAAHT---NRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVL 177 L ++ V G L+ A T N P SE A+LQGTAGSTG PRTA+LSP AV+ Sbjct 121 LLAETESTPVVCG-LAEATRTPASNDLRIPRDSEA-AILQGTAGSTGDPRTAVLSPTAVV 178 Query 178 SNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWL 237 +N+RG+ +R+ D ATD GCSWLP+YHDMGLAF+L+ L+G PLW APT AF+A+P RW Sbjct 179 NNMRGIAERLQLDGATDRGCSWLPIYHDMGLAFLLTCVLSGMPLWQAPTGAFSAAPLRWA 238 Query 238 SWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAP 297 WLS S AT+TA PNF Y +G+++ RVS+VDLG LRV +NGGEPVDC+G +FA AMAP Sbjct 239 EWLSASAATLTAGPNFGYATLGRFSGRVSDVDLGPLRVAINGGEPVDCEGFQQFATAMAP 298 Query 298 FGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISC 357 FGF A A P+YG+AESTCAVT+P GL D + K+A+LG PIPGME+RIS Sbjct 299 FGFRASAPTPAYGMAESTCAVTMPECADGLRIDERTESGSLQKYALLGRPIPGMELRIS- 357 Query 358 GDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPD---DWFATGDLGYLGAGGLVVCGRA 414 + IGE+EIRG SMM Y G D WF TGD+GYL G LV+CGR+ Sbjct 358 ----PAESDDAIGEVEIRGTSMMTRYFGDIGTASDLDAGWFRTGDIGYLVDGELVICGRS 413 Query 415 KEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANAR 474 KEVI+IAGRNIFPTE+E VA QV GVR+GAVVA+G+ +TR L++AAEF G D+ R Sbjct 414 KEVITIAGRNIFPTEIEQVAGQVDGVRQGAVVAVGSESGATRARLLIAAEFLGSDQEVTR 473 Query 475 AELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSL 517 + +I+RV S CG+ P+DVV + PGSLPRTSSGKLRRL V R L Sbjct 474 SAVIKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVGRRL 516 >gi|343925521|ref|ZP_08765040.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] gi|343764613|dbj|GAA11966.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] Length=554 Score = 501 bits (1291), Expect = 9e-140, Method: Compositional matrix adjust. Identities = 269/530 (51%), Positives = 351/530 (67%), Gaps = 13/530 (2%) Query 2 SELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLL---DHDRPAAVG 58 + LAA + +M A L VLD E+ W PW EVH AE +A LL D P AVG Sbjct 15 NTLAATVREAMLAGDTTLSVLDSESGEWVIAPWREVHARAEQIAVQLLADSDLHEPLAVG 74 Query 59 LVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSY 118 L+G+PTV+L+AAIQGAWLAG VSILPGP+RGA++ RWA+ T RF+ IGV TVL GS Sbjct 75 LIGDPTVDLIAAIQGAWLAGVPVSILPGPIRGADESRWAETTYRRFVSIGVGTVLGSGSQ 134 Query 119 LARLRSVD--TAGVTIGDLSTAAHTN-RSATPVASEGPAVLQGTAGSTGAPRTAILSPGA 175 L L VD + + AA T+ A V AVLQGTAGSTG P+TA+L+ A Sbjct 135 LDLLTKVDGQLRIARVAEYGIAADTSGFVARNVNPNSVAVLQGTAGSTGDPKTAVLTASA 194 Query 176 VLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFR 235 V SN L R+G D G +WLPLYHDMGL F+L+ G P ++ P TAF A+PF+ Sbjct 195 VYSNAIELVSRLGMHRTRDTGFTWLPLYHDMGLMFLLAGMTTGIPAYVVPNTAFAAAPFK 254 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAM 295 W+ WL+++ AT+TAAPNFAY+++G+Y + + ++DL LRV ++GGEP+D D +F EA Sbjct 255 WMQWLTETKATVTAAPNFAYDILGRYGKLLRDIDLSNLRVAISGGEPIDADAFDKFLEAT 314 Query 296 APFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI---DGSGA---HKHAVLGNPIP 349 APFGF+ A P+YG+AES CAVT+P G G D V G G ++A+LG P+ Sbjct 315 APFGFEPSAAAPAYGMAESACAVTMPAVGEGAHYDEVTVTPPGGGEPIRRRYALLGKPLG 374 Query 350 GMEVRISCGD-QAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGL 408 GM+VRI + R +G +EIRG SMM GYLG + +WFATGDLGYL L Sbjct 375 GMQVRIVEPNVDVPVIDGRSVGHVEIRGTSMMRGYLGGPDLGAGEWFATGDLGYLIDDRL 434 Query 409 VVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGP 468 V+CGRAKEVI +AGRN+FP E+E AA+V GVR G VVA+ G+ S+RPGLV+ AE++G Sbjct 435 VICGRAKEVIIVAGRNLFPIEIERAAAEVAGVRRGGVVAMARGEGSSRPGLVILAEYKGS 494 Query 469 DEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 D ARAE+ VAS CGI+P++V+FV+P ++PRT+SGK+RRL R+ +E Sbjct 495 DPDKARAEVNSEVASACGIMPAEVIFVAPDAVPRTTSGKIRRLETRQMVE 544 >gi|296392813|ref|YP_003657697.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM 44985] gi|296179960|gb|ADG96866.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM 44985] Length=541 Score = 478 bits (1229), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 263/531 (50%), Positives = 348/531 (66%), Gaps = 16/531 (3%) Query 2 SELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDH-DRPA-AVGL 59 + LAA ++ +M +++ DL+++D ET W R PW EVH AE+VAA LLD D P +GL Sbjct 7 NRLAAKISEAMLSTSADLVIMDAETREWSRFPWGEVHARAEAVAADLLDRADGPVGTLGL 66 Query 60 VGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYL 119 +G PTV++VA++ GAWLAG +VS+ PG VRGA+ RWA+ TL R IGVRT+ S G L Sbjct 67 IGNPTVDIVASVLGAWLAGGSVSLFPGMVRGADLGRWAETTLGRCAQIGVRTIFSYGREL 126 Query 120 ARLRSVDTAGVTIGDLSTAAHTNRSATPVA-----SEGPAVLQGTAGSTGAPRTAILSPG 174 +LR+V + GV D++ R + V PAVLQ ++GSTG P+TAILS G Sbjct 127 EQLRAVQS-GVRTEDVARIGAKPRPQSFVPPRTGDDSTPAVLQNSSGSTGQPKTAILSRG 185 Query 175 AVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPF 234 A LSN+ + R DV CSWLPLYHDMGL ++SA AGAPLWLAP+ AF+A+P Sbjct 186 AFLSNIAAVADRT-LLGKEDVVCSWLPLYHDMGLITLVSAMWAGAPLWLAPSGAFSAAPL 244 Query 235 RWLSWLSDSGATMTAAPNFAYNLIGKYARRVSE-VDLGALRVTLNGGEPVDCDGLTRFAE 293 +WL W+++SGAT APNFAY++IG+Y ++ VDLG LRV ++ E + CD RF Sbjct 245 KWLDWITESGATYVKAPNFAYDIIGRYGDKIDRGVDLGTLRVAVSAAELIHCDSFERFLA 304 Query 294 AMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVI-----DGSGAHKHAVLGNPI 348 A AP GF+ G+ + +YGLAE+TCAV PG G D V G ++A LG + Sbjct 305 ATAPVGFNPGSAMTAYGLAEATCAVAASRPGAGARFDDVSVTMPDGGQSRRRYARLGAAL 364 Query 349 PGMEVRISCGDQAAGNAS-REIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGG 407 GM +RI+ + RE+GEIE+ GA MM GYLG PI D+WF TGDLGYL G Sbjct 365 DGMRLRIAPPAAPVPAINGREVGEIEVTGACMMNGYLGADPIRRDEWFKTGDLGYLLDGE 424 Query 408 LVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG 467 LVV GR KE+I +AGRN++PT++E AA V GVR G V A+G + RP L +A E++G Sbjct 425 LVVVGRFKELIVLAGRNVYPTDIERAAASVEGVRAGRVAAVGLDEGGLRPRLALALEYKG 484 Query 468 PDEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLE 518 D AR ++QRVA++CGIVP++VVF +PG LP T+SGKLRRL V+ +E Sbjct 485 SDLDTARRRVVQRVAADCGIVPAEVVFAAPGELPVTTSGKLRRLDVKHMIE 535 >gi|325000634|ref|ZP_08121746.1| long-chain-fatty-acid--CoA ligase [Pseudonocardia sp. P1] Length=525 Score = 261 bits (667), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 190/489 (39%), Positives = 262/489 (54%), Gaps = 34/489 (6%) Query 56 AVG-LVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLS 114 AVG L GEP E+ A Q WL G +V++L P + WA+ T+T + VL Sbjct 30 AVGVLAGEPA-EIAPAAQAVWLCGGSVTMLHQPTPRTDLAVWAEDTVTTLKMVDAAMVLL 88 Query 115 QGSYLARLRSVDTAGV---TIGDLSTAAHTNRSATPVASEG-PAVLQGTAGSTGAPRTAI 170 + A + GV T+ L +A VA EG A+LQ T+GST AP+ Sbjct 89 GPPFDALAPVLTEQGVAFRTLDSLDGDPDAFTAAADVADEGDTALLQLTSGSTAAPKAVR 148 Query 171 LSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALA-GAPLWLAPTTAF 229 ++ G + +N+ + D ATD SWLPL+HDMG+ L+ + G L F Sbjct 149 ITHGNLHANIGSMVTASQLDVATDRMVSWLPLFHDMGMVGFLTVPMTVGLDLVTVTPADF 208 Query 230 TASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVS--EVDLGALRVTLNGGEPVDCDG 287 P W +S G T+TAAPNFAY ++ + RV E+DL +LR+ LNG EPVD Sbjct 209 LGRPRLWAELISRYGGTVTAAPNFAYAVLARQLARVDDGELDLSSLRIALNGAEPVDPAA 268 Query 288 LTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRV-IDGSGAHKHAV--- 343 + F A A FG +VL +YG+AE+ V GL DRV + AH+ A Sbjct 269 VEAFTVAGARFGLRPESVLCAYGMAETALGVAFAPVHTGLAVDRVDAEELEAHRRATPAG 328 Query 344 ---------LGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQ-PI---D 390 LG P+PG+EV++ G A RE+G + +RGA++ GYL + P+ D Sbjct 329 TAPARGFPELGPPLPGIEVKV-VGSGGADLGPREVGVLHLRGAAVTPGYLTVEGPLSTQD 387 Query 391 PDDWFATGDLGYLGAGG-LVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVA-- 447 D WF TGD GYL GG +VVCGR K+VI + GRNI+PT++E A + GVR G VVA Sbjct 388 ADGWFDTGDEGYLTDGGAVVVCGRTKDVIIMGGRNIYPTDIERAAGEADGVRAGNVVAVR 447 Query 448 LGTGDRSTRPGLVVAAEFRGPDEANA----RAELIQRVASECGIVPSDVVFVSPGSLPRT 503 + G+ R VA E +G D +A RA++++RV S G+ P++V ++PGSLP+T Sbjct 448 IAAGEGRHRESFAVAVEAKGADTDDAVKAIRADVVRRVVSAVGVRPAEVAVLAPGSLPKT 507 Query 504 SSGKLRRLA 512 SGKLRR A Sbjct 508 PSGKLRRAA 516 >gi|325676252|ref|ZP_08155931.1| acyl-CoA synthetase [Rhodococcus equi ATCC 33707] gi|325552813|gb|EGD22496.1| acyl-CoA synthetase [Rhodococcus equi ATCC 33707] Length=542 Score = 259 bits (661), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 190/519 (37%), Positives = 264/519 (51%), Gaps = 49/519 (9%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 R W EVH +A +A L D + A+G++ V++ A Q W+ G +V++L P Sbjct 28 LRQSWGEVHTIARRMAGALADAGIGSGDAIGVLAGMPVDIAPACQAIWMRGGSVTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAH-TNRSAT 146 + Q WA T I V+ + A + + G+ + + + + A Sbjct 88 TPRTDLQVWAQDTEAIIRMISAAAVVLGAPFEAAVPLLVERGIKVVTIESMRDGHDIDAV 147 Query 147 PVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDM 206 A A+ Q T+GSTG+P+ L+ +N + RV DV SWLPL+HDM Sbjct 148 ETAESDIALQQLTSGSTGSPKAVQLTHANFYANAYAMIDRVEFSPERDVMISWLPLFHDM 207 Query 207 GLAFVLSAALAGAPLWLAPTTA------FTASPFRWLSWLSDSGATMTAAPNFAYNLIGK 260 G+ L+ P+ + TT F +P W + T+TAAPNFAY+L+ Sbjct 208 GMIGFLTV-----PMQIGATTVHITPLDFLRTPLLWAELIGKYRGTVTAAPNFAYSLL-- 260 Query 261 YARRVS-----EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAEST 315 ARR++ E DL ++RV LNG EPVD D + A+A A FG D A+ P+YG+AE T Sbjct 261 -ARRLAQAPAGEYDLSSMRVLLNGAEPVDPDTMIALADAGARFGLDPLALAPTYGMAEVT 319 Query 316 CAVTVPVPGIGLLADRV----IDGSG---------AHKHAVLGNPIPGMEVRISCGDQAA 362 AV+VP PG GL+ DRV ++ G A A LG +PG+E R+ D Sbjct 320 LAVSVPEPGRGLVLDRVDPDLLEAGGLAVRSTRANARAMATLGPLVPGLEGRVVARD-GL 378 Query 363 GNASREIGEIEIRGASMMAGYLGQQ-PI---DPDDWFATGDLGYLGAGGL-VVCGRAKEV 417 R +G IE+RG S+ GYL P+ D D W TGD+GY L VVCGR K+V Sbjct 379 ELPKRAVGVIELRGKSVTPGYLTVDGPVATQDADGWINTGDIGYFTEDDLVVVCGRVKDV 438 Query 418 ISIAGRNIFPTEVELVAAQVRGVREG--AVVALGTGDRSTRPGLVVAAEFRGPDEANA-- 473 I + GRNI+PT++E A V GVR G A + L GD+ R G VA E D+A+ Sbjct 439 IIMGGRNIYPTDIERAAGSVSGVRPGNAAAIRLDAGDK--REGFAVAVETNAIDDADEVR 496 Query 474 --RAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 E+ V +E G+ P V + PGSLP+TSSGKLRR Sbjct 497 RIEREVAHAVVAEVGVRPRTVAVLGPGSLPKTSSGKLRR 535 >gi|126438180|ref|YP_001073871.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. JLS] gi|126237980|gb|ABO01381.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=544 Score = 257 bits (656), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 184/512 (36%), Positives = 258/512 (51%), Gaps = 36/512 (7%) Query 31 RHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGPV 88 RH W EVH A +A L A+ ++ VE+ QG W+ GA++++L P Sbjct 29 RHTWLEVHERALRIAGGLAAAGVGHGDAIAVLAGAPVEIAPTAQGIWMRGASLTMLHQPT 88 Query 89 RGANDQRWADATLTRFLGIGVRTVLSQGSYLA---RLRSVDTAGVTIGDLSTAAHTNRSA 145 + QRWAD T I + V+ ++ L + +T+ DL AH Sbjct 89 PRTDLQRWADETTAVIDMIDAKAVIVSEPFMPAAPLLSGLGMLVLTVADL--LAHEPGEM 146 Query 146 TPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 P + A++Q T+GSTG+P+ +S V++N + D TDV SWLP +HD Sbjct 147 VPTGDDDIALMQLTSGSTGSPKAVQISHANVVANAEAMIVGCEFDIETDVIVSWLPCFHD 206 Query 206 MGLAFVLSAALA-GAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ L+ + GA L F W + TMTAAPNFAY L K RR Sbjct 207 MGMTGYLTVPMYFGAELVKVTPMDFLHDTLLWAKLIHKYRGTMTAAPNFAYTLFAKRLRR 266 Query 265 VS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVP 321 ++ E DL +LR L+G E VD + EA APFG A++P+YG+AE+T AV+ Sbjct 267 LATPGEFDLSSLRWALSGAEQVDPLDVEDLCEAGAPFGLKPEAIIPAYGMAETTVAVSFS 326 Query 322 VPGIGLLAD-----------RVIDGSGAHKHAV--LGNPIPGMEVRISCGDQAAGNASRE 368 G G++ D R + + H + LG P+PG+EVR+ D A A R Sbjct 327 ECGRGMVVDEVDADLLSVLHRAVPANKGHTRRLVSLGRPLPGLEVRVLDEDGAVLPA-RG 385 Query 369 IGEIEIRGASMMAGYLGQQPIDPDD----WFATGDLGYLG-AGGLVVCGRAKEVISIAGR 423 +G IE+RG + GY P W+ TGDLGYL AG +VVCGR K+VI +AGR Sbjct 386 VGVIEVRGRPVSRGYTTTAGFVPAQDELGWYDTGDLGYLTEAGEVVVCGRLKDVIIMAGR 445 Query 424 NIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR--- 480 NI+PT++E AA+V GVR G VA+ R VA E + ++ + IQR Sbjct 446 NIYPTDIERAAARVDGVRPGCAVAIRLDGGHPRETFAVAVESKHFEDVK-QVRRIQRQVA 504 Query 481 --VASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PG +P+T SGKLRR Sbjct 505 HEVVAEVDVRPRNVVVLEPGMIPKTPSGKLRR 536 >gi|134097414|ref|YP_001103075.1| long-chain-fatty-acid--CoA ligase [Saccharopolyspora erythraea NRRL 2338] gi|291004596|ref|ZP_06562569.1| long-chain-fatty-acid--CoA ligase [Saccharopolyspora erythraea NRRL 2338] gi|133910037|emb|CAM00149.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] Length=511 Score = 256 bits (655), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 186/506 (37%), Positives = 259/506 (52%), Gaps = 33/506 (6%) Query 37 VHGLAESVAAWLLDHDRPA-AVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQR 95 +H +A +A L D RP AV ++ + A+QG WL+G +V++L P + Sbjct 1 MHSVALRMAGALRDDVRPGDAVAILAADPGLIAPAVQGVWLSGGSVTMLHQPTPRTDLGH 60 Query 96 WADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPV--ASEGP 153 WA TL IG R VL G +L + + L A PV + Sbjct 61 WAQDTLRVLSMIGARLVL-LGPPFDQLSGLLSENAIEHRLLAELDGEPPAGPVEVGEDAT 119 Query 154 AVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLS 213 A+LQ T+GST P+ ++ G + SN+RG+ DA DV SWLPL+HDMG+ L+ Sbjct 120 ALLQLTSGSTADPKAVRITHGNLHSNMRGMVTAAELDAERDVAVSWLPLFHDMGMVGCLT 179 Query 214 AALAGAPLWLAPTTA-FTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSE--VDL 270 +A + T A F A P W +S T+TAAPNFAY ++G+ R E DL Sbjct 180 VPMAIGMEAVKVTPADFLARPLLWPELISRHRGTVTAAPNFAYAVVGRRMERADEGQFDL 239 Query 271 GALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLAD 330 LR TLNG EP+D F +A A FG D ++ ++G+AEST AV+ G G+ D Sbjct 240 STLRFTLNGAEPIDPAAARAFTDAGARFGLDPDCMVCAFGMAESTLAVSFAPLGCGIEVD 299 Query 331 RVIDGS---------------GAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIR 375 + G+ A + A+LG P+PG+EV + D RE+G + IR Sbjct 300 TIDAGALEEQRRAVPVDAGEERARRFALLGRPLPGLEVDV-VDDAGKRLGEREVGRLRIR 358 Query 376 GASMMAGYLGQQ-PI---DPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVE 431 G ++ GYL P+ D W TGD GYL G +V+CGR K+VI + GRNI+P ++E Sbjct 359 GDAVTPGYLTVDGPLATQDEQGWLDTGDEGYLVDGQVVICGRRKDVIIMGGRNIYPVDIE 418 Query 432 LVAAQVRGVREG--AVVALGTGDRSTRPGLVVAAEFRGPDEANARA---ELIQRVASECG 486 A +V GVR G A V G R R +V+ ++ DEA +A E+ RV G Sbjct 419 RAACEVDGVRPGNAAAVRQEAGTRRERFAVVLESKL-ADDEAAVKALRKEVAARVVDAVG 477 Query 487 IVPSDVVFVSPGSLPRTSSGKLRRLA 512 + PS VV + PG+LP+T SGKLRR A Sbjct 478 VRPSAVVVLRPGTLPKTPSGKLRRAA 503 >gi|256374801|ref|YP_003098461.1| long-chain-fatty-acid--CoA ligase [Actinosynnema mirum DSM 43827] gi|255919104|gb|ACU34615.1| AMP-dependent synthetase and ligase [Actinosynnema mirum DSM 43827] Length=546 Score = 256 bits (654), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 186/508 (37%), Positives = 261/508 (52%), Gaps = 36/508 (7%) Query 34 WPEVHGLAESVAAWLLDHDRP--AAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGA 91 W +VH A VA L++ AAV ++ E+ A+QGAWLAGA+ ++L P Sbjct 35 WAQVHARATRVAGALVEAGVTPGAAVAVLAGDPAEIAPAVQGAWLAGASTTMLHQPTART 94 Query 92 NDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTA-GVT---IGDLSTAAHTNRSATP 147 + WA+ T+ R LG+ ++ G+ L V G+T I DL T P Sbjct 95 DLAEWAEDTV-RVLGMIDSGLVLLGAPFDALSPVLVERGITHHRITDLDADPLTTPVEVP 153 Query 148 VASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMG 207 ++ A+LQ T+GST P+ ++ G + SN+ G+ + V D D SWLPL+HDMG Sbjct 154 ESAT--ALLQLTSGSTAHPKAVRITHGNLWSNMEGMREAVHLDPEVDRMVSWLPLFHDMG 211 Query 208 LA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVS 266 + F+ L G L F P W +S T+TAAPNFAY ++ K R ++ Sbjct 212 MVGFLTLPMLYGVDLVKVTPVDFLGRPVLWPELISRHRGTITAAPNFAYAVVAKRMRGLA 271 Query 267 --EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPG 324 E+DL +LR+ LNG EP+D + + F A FG +VL +YG+AE+T VT Sbjct 272 DGELDLSSLRIALNGAEPIDPEAVRSFTAEGARFGLPPESVLCAYGMAETTLGVTFAPVF 331 Query 325 IGLLADRVIDGS--------------GAHKHAVLGNPIPGMEVRISCGDQAAGNASREIG 370 G+ D V+D GA A+LG P+PG+E+R+ D R +G Sbjct 332 TGMAVD-VVDADLLEAERRAEPSAEPGARSFALLGPPLPGLEIRV-VDDAGTLLGDRRVG 389 Query 371 EIEIRGASMMAGYL---GQQPID-PDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIF 426 +++RG ++ GYL G P P W TGD GYL +VVCGR K+VI + GRNI+ Sbjct 390 RLQVRGEAVTPGYLTVDGPVPTTGPGGWLDTGDQGYLVGEQVVVCGRLKDVIIMGGRNIY 449 Query 427 PTEVELVAAQVRGVREGAVVA--LGTGDRSTRPGLVVAAEFRGPDEANAR--AELIQRVA 482 PT+VE A V GVR G VA L G R R +VV + F +E R + +V Sbjct 450 PTDVERAATAVDGVRAGNAVAVRLDAGTRRERFAVVVESRFASEEEEVKRLTKAITAKVV 509 Query 483 SECGIVPSDVVFVSPGSLPRTSSGKLRR 510 G+ P VV + PGS+P+T SGKLRR Sbjct 510 DAVGVRPFSVVVLPPGSVPKTPSGKLRR 537 >gi|312138679|ref|YP_004006015.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] gi|311888018|emb|CBH47330.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] Length=542 Score = 256 bits (654), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 190/520 (37%), Positives = 263/520 (51%), Gaps = 51/520 (9%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 R W EVH +A +A L D + A+G++ V++ A Q W+ G +V++L P Sbjct 28 LRQSWGEVHTIARRMAGALADAGIGSGDAIGVLAGMPVDIAPACQAIWMRGGSVTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATP 147 + Q WA T I V+ + A + + G+ + + + P Sbjct 88 TPRTDLQVWAQDTEAIIRMISAAAVVVGAPFEAAVPLLVERGIEVVTIESM-RDGHDVEP 146 Query 148 V--ASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 V A A+ Q T+GSTG+P+ L+ +N + RV DV SWLPL+HD Sbjct 147 VETAESDIALQQLTSGSTGSPKAVQLTHANFYANAYAMIDRVEFSPERDVMISWLPLFHD 206 Query 206 MGLAFVLSAALAGAPLWLAPTTA------FTASPFRWLSWLSDSGATMTAAPNFAYNLIG 259 MG+ L+ P+ + TT F +P W + T+TAAPNFAY+L+ Sbjct 207 MGMIGFLTV-----PMQIGATTVHITPLDFLRTPLLWAELIGKYRGTVTAAPNFAYSLL- 260 Query 260 KYARRVS-----EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAES 314 ARR++ E DL ++RV LNG EPVD D + A+A A FG D A+ P+YG+AE Sbjct 261 --ARRLAQAPAGEYDLSSMRVLLNGAEPVDPDTMIALADAGARFGLDPLALAPTYGMAEV 318 Query 315 TCAVTVPVPGIGLLADRV----IDGSG---------AHKHAVLGNPIPGMEVRISCGDQA 361 T AV+VP PG GL+ DRV ++ G A A LG +PG+E R+ D Sbjct 319 TLAVSVPEPGRGLVLDRVDPDLLEAGGLAVRSTRANARAMATLGPLVPGLEGRVVARD-G 377 Query 362 AGNASREIGEIEIRGASMMAGYLGQQ-PI---DPDDWFATGDLGYLGAGGL-VVCGRAKE 416 R +G IE+RG S+ GYL P+ D D W TGD+GY L VVCGR K+ Sbjct 378 LELPKRAVGVIELRGKSVTPGYLTVDGPVATQDADGWINTGDIGYFTEDDLVVVCGRVKD 437 Query 417 VISIAGRNIFPTEVELVAAQVRGVREG--AVVALGTGDRSTRPGLVVAAEFRGPDEANA- 473 VI + GRNI+PT++E A V GVR G A + L GD+ R VA E D+A+ Sbjct 438 VIIMGGRNIYPTDIERAAGSVSGVRPGNAAAIRLDAGDK--RESFAVAVETNAIDDADEV 495 Query 474 ---RAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 E+ V +E G+ P V + PGSLP+TSSGKLRR Sbjct 496 RRIEREVAHAVVAEVGVRPRTVAVLGPGSLPKTSSGKLRR 535 >gi|145225792|ref|YP_001136470.1| long-chain-fatty-acid--CoA ligase [Mycobacterium gilvum PYR-GCK] gi|315442504|ref|YP_004075383.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|145218278|gb|ABP47682.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|315260807|gb|ADT97548.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=544 Score = 255 bits (651), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 184/513 (36%), Positives = 263/513 (52%), Gaps = 38/513 (7%) Query 31 RHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGPV 88 RH W EVH A +A L AV ++ VE+ A QG W+ GA+V+++ P Sbjct 29 RHTWEEVHQRARRIAGGLAAAGVGHGDAVAMLAGAPVEIAPAAQGVWMRGASVTMVHQPT 88 Query 89 RGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVT---IGDLSTAAHTNRSA 145 + RWAD T + I V+ ++A + G+T I DL TA + Sbjct 89 PRTDLIRWADETTSVIDMISASAVVISDPFMAAAPLLSGMGMTVLSIADLLTAEPIDPVD 148 Query 146 TPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 T + A++Q T+GSTG+P+ ++ +++N + D TDV SWLP +HD Sbjct 149 T--CDDDIALMQLTSGSTGSPKAVQITHANIVANADAMTAGCDFDIDTDVIVSWLPCFHD 206 Query 206 MGLAFVLSAALA-GAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ L+ + GA L F W + TMTAAPNFAYNL+ + RR Sbjct 207 MGMTGYLTVPMYFGAELVKITPMDFLGDILLWPRLIHKYRGTMTAAPNFAYNLLARRLRR 266 Query 265 VS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVP 321 + E DL +LR L+G E VD D + A APFG AV+P+YG+AE+T AV+ Sbjct 267 QATPGEFDLSSLRWALSGAEQVDPDDVEDLCAAGAPFGLRPEAVIPAYGMAETTVAVSFS 326 Query 322 VPGIGLLAD-----------RVIDGSGAHKHAV--LGNPIPGMEVRISCGDQAAGNASRE 368 G G++ D R + + H + LG P+ G+E+RI D AA R Sbjct 327 ECGGGMVVDEVDADLLAVLHRAVPAAKGHTRRLVALGRPLAGLEMRIVDEDGAALQ-PRG 385 Query 369 IGEIEIRGASMM------AGYLGQQPIDPDDWFATGDLGYLGAGG-LVVCGRAKEVISIA 421 +G IE+RG S+ AG++ Q D W+ TGD+GYL G +VVCGR K+VI +A Sbjct 386 VGVIEVRGQSVTRGYTTAAGFIAAQ--DDRGWYDTGDIGYLTEDGDVVVCGRLKDVIIMA 443 Query 422 GRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG-PDEANAR---AEL 477 GRNIFP ++E A++V GVR G VA+ +R VA E + DE R ++ Sbjct 444 GRNIFPADIERAASRVEGVRPGCAVAVRLDAGRSRESFAVAVESKHFDDEVEVRRVERQV 503 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PG++P+T SGKLRR Sbjct 504 AHEVFAEVDVRPRNVVVLEPGTIPKTPSGKLRR 536 >gi|257057208|ref|YP_003135040.1| long-chain-fatty-acid--CoA ligase [Saccharomonospora viridis DSM 43017] gi|256587080|gb|ACU98213.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Saccharomonospora viridis DSM 43017] Length=560 Score = 254 bits (650), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 189/523 (37%), Positives = 262/523 (51%), Gaps = 45/523 (8%) Query 30 CRHPWPEVHGLAESVAAWL----LDHDRPAAVGLVGEPTVELVA-AIQGAWLAGAAVSIL 84 R W EVH A +A L L+ AV L G P EL+A +QG WLAG +V++L Sbjct 30 VRRTWFEVHQRARRIAGGLVAAGLEPGGAVAV-LAGAP--ELIAPTVQGVWLAGGSVTML 86 Query 85 PGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRS 144 P + +WA+ TL IG V+ + +D G+ ++ Sbjct 87 HQPTARTDLAKWAEDTLRVLRMIGSSLVVLGEPFDGLASVLDEHGIAYRAINDLLEAEPL 146 Query 145 ATPVASEGPAV--LQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPL 202 A PVA E A+ LQ T+G+T P+ ++ + SN+ + +R D +DV SWLPL Sbjct 147 AEPVAVEEDALALLQLTSGATADPKAVKITHANLYSNISAMIERAEFDVESDVMVSWLPL 206 Query 203 YHDMGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKY 261 +HDMG+ F+ + G L F + P W +S T TAAPNFAY ++G+ Sbjct 207 FHDMGMVGFLTVPMVFGVELIKITPVDFLSGPLVWPELISKYRGTTTAAPNFAYAIVGRR 266 Query 262 ARRVSE---VDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAV 318 +V + DL LR+ LNG EP+D + F EA A FG A V P+YGLAE+T AV Sbjct 267 LAKVEDDKAYDLSTLRIALNGAEPIDPTAVRTFTEAGARFGMPAECVFPAYGLAEATLAV 326 Query 319 TVPVPGIGLLADRV--------------------IDGSGAHKHAVLGNPIPGMEVRISCG 358 + GL D V + A+LG P+ G+EVRI G Sbjct 327 SFAPLFTGLTVDTVAADPLEADNRAVPVAEDDPRYGTDQVRQFAMLGYPLSGLEVRI-VG 385 Query 359 DQAAGNASREIGEIEIRGASMMAGYLGQQ-PIDPDD---WFATGDLGYLGAGGLVVCGRA 414 + RE+GEI +RG ++ GY P+D D WFATGD+GYL G +V+CGR Sbjct 386 EDGTVRGDREVGEIHLRGDAVSPGYRTVDGPVDTQDAEGWFATGDIGYLVDGQVVICGRK 445 Query 415 KEVISIAGRNIFPTEVELVAAQVRGVREGAVVA--LGTGDRSTRPGLVVAAEFRGPDEAN 472 K+VI + GRN++PT++E A V GVR G VA + G R R +V+ + G EA Sbjct 446 KDVIILGGRNVYPTDIERAATSVPGVRAGNAVAVRIDAGTRRERFAVVLESTVAGDAEAE 505 Query 473 ARA---ELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLA 512 RA E+ RV + P VV + GSLP+T SGK++R A Sbjct 506 -RALANEVAARVRAAVDARPYSVVVLPKGSLPKTPSGKVKRAA 547 >gi|226365171|ref|YP_002782954.1| long-chain-fatty-acid--CoA ligase [Rhodococcus opacus B4] gi|226243661|dbj|BAH54009.1| putative fatty-acid--CoA ligase [Rhodococcus opacus B4] Length=544 Score = 254 bits (650), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 175/510 (35%), Positives = 258/510 (51%), Gaps = 31/510 (6%) Query 30 CRHPWPEVHGLAESVAAWLLDHD--RPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 R PW E+H A +A L D A+G++ V++ + Q W+ GA+V++L P Sbjct 28 LRQPWGEIHKAARHMAGALADAGIAHGDAIGILAGQPVDIAPSCQATWMRGASVTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATP 147 + WA T T I + V+ + A ++ G+T+ + T + + P Sbjct 88 TPRTDLAVWAKDTETVITMIDAKAVILGAPFDAAKPLLEERGITVLTV-TELNEGTAIDP 146 Query 148 VAS--EGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 V + A+ Q T+GSTG+P+ ++ +N + R+ DV SWLPL+HD Sbjct 147 VETFESDIALQQLTSGSTGSPKAVQITHENFYTNAYAMIDRIKFSIEDDVMISWLPLFHD 206 Query 206 MGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ LS + GA + F +P W + T+TAAPNFAY+L+ + ++ Sbjct 207 MGMVGFLSVPMQVGAEVVSITPMDFLRTPLLWAELMGKYQGTVTAAPNFAYSLLARRLKQ 266 Query 265 VSE--VDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPV 322 + VDL +R NG EPVD D + AEA A FG + A+ P YG+AE+T AV++P Sbjct 267 AEDGAVDLSTVRYMWNGAEPVDPDTMNALAEAGARFGLNPSALAPVYGMAETTLAVSIPD 326 Query 323 PGIGLLADRV-------------IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREI 369 P G + DRV + A A LG +P +E R+ D +R + Sbjct 327 PDQGQVLDRVDPDLLEAMQRAVPSNKPNARALATLGKMVPNLEGRVVDTDGEL-LPTRGV 385 Query 370 GEIEIRGASMMAGYL---GQQPI-DPDDWFATGDLGYLGAGGL-VVCGRAKEVISIAGRN 424 G IE+RG ++ GY+ G +P D + W TGD+GY GL VVCGR K+VI + GRN Sbjct 386 GIIEVRGKAVTPGYITLDGHKPAQDANGWLNTGDVGYFTEEGLVVVCGRVKDVIIMGGRN 445 Query 425 IFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAE---FRGPDEAN-ARAELIQR 480 I+PT++E A V GVR G VA+ R VA E ++ P+ E++ Sbjct 446 IYPTDIERAAGTVAGVRPGNAVAVRLDAGQKRESFAVAVETNDYQDPETVKRIEHEVVHA 505 Query 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V SE G+ P V + PGS+P+TSSGKLRR Sbjct 506 VFSEVGVRPRTVAVLGPGSIPKTSSGKLRR 535 >gi|108802198|ref|YP_642395.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. MCS] gi|119871351|ref|YP_941303.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. KMS] gi|108772617|gb|ABG11339.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119697440|gb|ABL94513.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] Length=544 Score = 254 bits (650), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 182/512 (36%), Positives = 257/512 (51%), Gaps = 36/512 (7%) Query 31 RHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGPV 88 RH W EVH A +A L A+ ++ VE+ QG W+ GA++++L P Sbjct 29 RHTWLEVHERALRIAGGLAAAGVGHGDAIAVLAGAPVEIAPTAQGIWMRGASLTMLHQPT 88 Query 89 RGANDQRWADATLTRFLGIGVRTVLSQGSYLAR---LRSVDTAGVTIGDLSTAAHTNRSA 145 + QRWAD T I + V+ ++ L + +T+ +L AH Sbjct 89 PRTDLQRWADETTAVIDMIDAKAVIVSEPFMPAAPLLSGLGMLVLTVAEL--LAHEPGEM 146 Query 146 TPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 P + A++Q T+GSTG+P+ +S V++N + D TDV SWLP +HD Sbjct 147 VPTGDDDIALMQLTSGSTGSPKAVQISHANVVANAEAMIVGCEFDIETDVIVSWLPCFHD 206 Query 206 MGLAFVLSAALA-GAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ L+ + GA L F W + TMTAAPNFAY L K RR Sbjct 207 MGMTGYLTVPMYFGAELVKVTPMDFLHDTLLWAKLIHKYRGTMTAAPNFAYTLFAKRLRR 266 Query 265 VS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVP 321 ++ E DL +LR L+G E VD + EA PFG A++P+YG+AE+T AV+ Sbjct 267 LATPGEFDLSSLRWALSGAEQVDPLDVEDLCEAGVPFGLKPEAIIPAYGMAETTVAVSFS 326 Query 322 VPGIGLLAD-----------RVIDGSGAHKHAV--LGNPIPGMEVRISCGDQAAGNASRE 368 G G++ D R + + H + LG P+PG+EVR+ D A A R Sbjct 327 ECGRGMVVDEVDADLLSVLHRAVPANKGHTRRLVSLGRPLPGLEVRVLDEDGAVLPA-RG 385 Query 369 IGEIEIRGASMMAGYLGQQPIDPDD----WFATGDLGYLG-AGGLVVCGRAKEVISIAGR 423 +G IE+RG + GY P W+ TGDLGYL AG +VVCGR K+VI +AGR Sbjct 386 VGVIEVRGRPVSRGYTTTAGFVPAQDELGWYDTGDLGYLTEAGEVVVCGRLKDVIIMAGR 445 Query 424 NIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQR--- 480 NI+PT++E AA+V GVR G VA+ R VA E + ++ + IQR Sbjct 446 NIYPTDIERAAARVDGVRPGCAVAIRLDGGHPRETFAVAVESKHFEDVK-QVRRIQRQVA 504 Query 481 --VASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PG +P+T SGKLRR Sbjct 505 HEVVAEVDVRPRNVVVLEPGMIPKTPSGKLRR 536 >gi|229494919|ref|ZP_04388670.1| acyl-CoA synthase [Rhodococcus erythropolis SK121] gi|229318143|gb|EEN84013.1| acyl-CoA synthase [Rhodococcus erythropolis SK121] Length=544 Score = 254 bits (649), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 188/540 (35%), Positives = 270/540 (50%), Gaps = 45/540 (8%) Query 8 LTRSMQASAGDLMVLDR-----ETSLWCRHPWPEVHGLAESVAAWLLD--HDRPAAVGLV 60 T M A+A V DR E R W ++H A +A L + DR A+G++ Sbjct 4 FTEEMYATAA---VTDRGLVTGEPDNAFRQTWGDIHQEARRMAGGLAEVGIDRGVAIGIL 60 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 V++ A Q W+ GA+V++L P + WA T T I + V+ + A Sbjct 61 AGQPVDIAPACQATWMRGASVTMLHQPTPRTDLGVWAQDTETVIDMISAKAVILGAPFDA 120 Query 121 RLRSVDTAGVTIGDLSTAAHTNRSATPV--ASEGPAVLQGTAGSTGAPRTAILSPGAVLS 178 ++ G+T+ + + S PV A A+ Q T+GSTG+P+ ++ + Sbjct 121 AKPLLEERGITVVTVDEL-RSGTSIDPVETAESDIALQQLTSGSTGSPKAVQITHENFYT 179 Query 179 NLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWL 237 N + R+ DV SWLPL+HDMG+ L+ + GA + F +P W Sbjct 180 NAYAMINRIKFSIEDDVMVSWLPLFHDMGMVGFLTVPMQVGAEVISITPMDFLRTPVLWA 239 Query 238 SWLSDSGATMTAAPNFAYNLIGKYARRVSE-----VDLGALRVTLNGGEPVDCDGLTRFA 292 + G T+TAAPNFAY+L+ ARR+++ VDL ++R NG EPVD D + A Sbjct 240 ELMGKYGGTVTAAPNFAYSLL---ARRLAQAEDGAVDLSSVRYMWNGAEPVDPDTMDALA 296 Query 293 EAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRV-------------IDGSGAH 339 EA A FG + A+ P YG+AE+T AV++P P G + D V + A Sbjct 297 EAGARFGLNPTALAPVYGMAETTLAVSIPDPDQGQVLDYVDPDFLESMSRAVPSNRPNAR 356 Query 340 KHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYL---GQQPIDPDD-WF 395 A LG +P +E RI D A R +G IE+RG ++ GY+ G +P DD W Sbjct 357 ALATLGKMVPDLEGRIVDRDGQVLPA-RGVGIIEVRGKAVTPGYVTVDGHKPAQDDDGWL 415 Query 396 ATGDLGYLGAGGL-VVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRS 454 TGD+GY GL VVCGR K+VI + GRN++PT++E A V GVR G VA+ Sbjct 416 DTGDVGYFTEEGLVVVCGRVKDVIIMGGRNVYPTDIERAAGTVAGVRPGNAVAIRLDAGQ 475 Query 455 TRPGLVVAAE---FRGPDEAN-ARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 R VA E F P+E E++ V ++ G+ P V + PGS+P+TSSGKLRR Sbjct 476 KRESFAVAVETNAFEDPEEVKRIEREVVHAVVADVGVRPRAVAVLGPGSIPKTSSGKLRR 535 >gi|111022658|ref|YP_705630.1| long-chain-fatty-acid--CoA ligase [Rhodococcus jostii RHA1] gi|110822188|gb|ABG97472.1| probable acyl-CoA synthetase [Rhodococcus jostii RHA1] Length=549 Score = 253 bits (646), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 175/510 (35%), Positives = 259/510 (51%), Gaps = 33/510 (6%) Query 31 RHPWPEVHGLAESVAAWLLDHD--RPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPV 88 R PW E+H A +A L + A+G++ V++ + QG W+ GA+V++L P Sbjct 35 RQPWGEIHKAARRMAGALAEAGIGHGDAIGILAGQPVDIAPSCQGTWMRGASVTMLHQPT 94 Query 89 RGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAG---VTIGDLSTAAHTNRSA 145 + WA T T I + V+ + A ++ G VT+ +L+ T+ Sbjct 95 PRTDLAVWAKDTETVINMIQAKAVILGAPFDAAKPLLEERGITVVTVAELNEGTETDPVE 154 Query 146 TPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 T A+ Q T+GSTG+P+ ++ +N + R+ DV SWLPL+HD Sbjct 155 T--FESDIALQQLTSGSTGSPKAVQVTHENFYTNAYAMIDRIKFSIEDDVMISWLPLFHD 212 Query 206 MGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ LS + GA + F +P W + T+TAAPNFAY+L+ + ++ Sbjct 213 MGMVGFLSVPMQVGAEVVSITPMDFLRTPLLWAELMGKYKGTVTAAPNFAYSLLARRLKQ 272 Query 265 VSE--VDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPV 322 + VDL +R NG EPVD + + + AEA A FG + A+ P YG+AE+T AV++P Sbjct 273 AEDGAVDLSTVRYMWNGAEPVDPETMNKLAEAGARFGLNPSALAPVYGMAETTLAVSIPD 332 Query 323 PGIGLLAD-----------RVIDGS--GAHKHAVLGNPIPGMEVRISCGDQAAGNASREI 369 P G + D R + S A A LG +P +E R+ + +R + Sbjct 333 PDQGQVLDLVDPDLLEAMQRAVPSSKPNARALATLGKMVPNLEGRV-VDSEGELLPTRGV 391 Query 370 GEIEIRGASMMAGYL---GQQPI-DPDDWFATGDLGYLGAGGL-VVCGRAKEVISIAGRN 424 G IE+RG ++ GY+ G +P D D W TGD+GY GL VVCGR K+VI + GRN Sbjct 392 GIIEVRGKAVTPGYITVDGHKPAQDADGWLNTGDVGYFTEEGLVVVCGRVKDVIIMGGRN 451 Query 425 IFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAE---FRGPDEAN-ARAELIQR 480 I+PT++E A V GVR G VA+ R VA E ++ P+ E++ Sbjct 452 IYPTDIERAAGTVAGVRPGNAVAVRLDAGQKRESFAVAVETNDYQDPEVVKRIEHEVVHA 511 Query 481 VASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V SE G+ P V + PGS+P+TSSGKLRR Sbjct 512 VFSEVGVRPRTVAVLGPGSIPKTSSGKLRR 541 >gi|118619726|ref|YP_908058.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118571836|gb|ABL06587.1| polyketide synthase Pks16 [Mycobacterium ulcerans Agy99] Length=544 Score = 253 bits (646), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 187/542 (35%), Positives = 270/542 (50%), Gaps = 38/542 (7%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPA--AVG 58 MS + R+ + + ++ + T + RH W EVH A +A L AVG Sbjct 1 MSRFTEKMFRNARETTKGMVTGEPHTPV--RHTWGEVHERARQIAGGLAAAGVGPGDAVG 58 Query 59 LVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSY 118 ++ VE+ QG W+ GA++++L P + WA+ T T I + V+ + Sbjct 59 VLAGAPVEIAPTAQGLWIRGASLTMLHQPTPRTDLALWAEDTTTVVDMIEAKAVVISDPF 118 Query 119 LARLRSVDTAGVTIGDLSTA-AHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVL 177 +A ++ G+ + A V + A++Q T+GSTG+P+ ++ + Sbjct 119 MAAAPVLEERGIRVLTFEQLLASEPIDPVEVGEDELALMQLTSGSTGSPKAVQITHRNLF 178 Query 178 SNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAAL--AGAPLWLAPTTAFTASPFR 235 +NL + DA TDV SWLPL+HDMG+ L+ + AG + + P F Sbjct 179 ANLEAMYISAEYDAETDVMVSWLPLFHDMGMIGFLTVPMYFAGELVKVTPMD-FMRDTLL 237 Query 236 WLSWLSDSGATMTAAPNFAYNLIGKYARRVS---EVDLGALRVTLNGGEPVDCDGLTRFA 292 W + TMTAAPNFAY+L K R+ + + DL +LR L+G EPV+ + Sbjct 238 WAKLIDKYKGTMTAAPNFAYSLFAKRLRKQAKPGQFDLSSLRFALSGAEPVEPSDVEDLC 297 Query 293 EAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRV-IDGSGAHKHAV-------- 343 EA APFG A+LP+YG+AE T AV G GL+ D V D A + AV Sbjct 298 EAGAPFGLRPQAILPAYGMAEITLAVAFSECGAGLVVDEVDADLMAALRRAVPAAKGNTR 357 Query 344 ----LGNPIPGMEVRISCGDQAAGNA--SREIGEIEIRGASMMAGYLGQQPIDPDD---- 393 LG + G+E RI D GN SR +G IE+RG S+ GYL P Sbjct 358 RLASLGPLLQGIEARIVDAD---GNVLPSRGVGVIELRGESVTPGYLTMGGFIPAQDQLG 414 Query 394 WFATGDLGY-LGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGD 452 W+ TGDLGY + G +VVCGR K+VI +AGRNI+PT++E A +V GVR G VA+ Sbjct 415 WYDTGDLGYQMENGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVEGVRPGCAVAVRLDA 474 Query 453 RSTRPGLVVAAE---FRGPDEA-NARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKL 508 +R VA E F P E ++ V +E + P +VV + PG++P+T SGKL Sbjct 475 GHSRETFAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSGKL 534 Query 509 RR 510 RR Sbjct 535 RR 536 >gi|226307814|ref|YP_002767774.1| fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] gi|226186931|dbj|BAH35035.1| putative fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] Length=573 Score = 253 bits (645), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 186/539 (35%), Positives = 268/539 (50%), Gaps = 43/539 (7%) Query 8 LTRSMQASAGDLMVLDR-----ETSLWCRHPWPEVHGLAESVAAWLLD--HDRPAAVGLV 60 T M A+A V DR E R W ++H A +A L + DR A+G++ Sbjct 33 FTEEMYATAA---VTDRGLVTGEPDNAFRQTWGDIHQEARRMAGGLAEVGIDRGVAIGIL 89 Query 61 GEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLA 120 V++ A Q W+ GA+V++L P + WA T T I + V+ + A Sbjct 90 AGQPVDIAPACQATWMRGASVTMLHQPTPRTDLGIWAQDTETVIDMISAKAVILGAPFDA 149 Query 121 RLRSVDTAGVTIGDLST-AAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSN 179 ++ G+T+ + T+ A A+ Q T+GSTG+P+ ++ +N Sbjct 150 AKPLLEERGITVVTVDELRGGTSIDPVETAESDIALQQLTSGSTGSPKAVQITHENFYTN 209 Query 180 LRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWLS 238 + R+ DV SWLPL+HDMG+ L+ + GA + F +P W Sbjct 210 AYAMINRIKFSIEDDVMVSWLPLFHDMGMVGFLTVPMQVGAEVISITPMDFLRTPVLWAE 269 Query 239 WLSDSGATMTAAPNFAYNLIGKYARRVSE-----VDLGALRVTLNGGEPVDCDGLTRFAE 293 + G T+TAAPNFAY+L+ ARR+++ VDL ++R NG EPVD D + AE Sbjct 270 LMGKYGGTVTAAPNFAYSLL---ARRLAQAEDGAVDLSSVRYMWNGAEPVDPDTMDALAE 326 Query 294 AMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRV-------------IDGSGAHK 340 A A FG + A+ P YG+AE+T AV++P P G + D V + A Sbjct 327 AGARFGLNPTALAPVYGMAETTLAVSIPDPDQGQVLDYVDPDFLESMSRAVPSNRPNARA 386 Query 341 HAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYL---GQQPI-DPDDWFA 396 A LG +P +E RI D A R +G IE+RG ++ GY+ G +P D D W Sbjct 387 LATLGKMVPDLEGRIVDRDGQVLPA-RGVGIIEVRGKAVTPGYVTVEGHKPAQDSDGWLD 445 Query 397 TGDLGYLGAGGL-VVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRST 455 TGD+GY GL VVCGR K+VI + GRN++PT++E A V GVR G VA+ Sbjct 446 TGDVGYFTEEGLVVVCGRVKDVIIMGGRNVYPTDIERAAGSVAGVRPGNAVAIRLDAGQK 505 Query 456 RPGLVVAAE---FRGPDEAN-ARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 R VA E F P+E E++ V ++ G+ P V + PGS+P+TSSGKLRR Sbjct 506 RESFAVAVETNAFEDPEEVKRIEREVVHAVVADVGVRPRAVAVLGPGSIPKTSSGKLRR 564 >gi|183984446|ref|YP_001852737.1| polyketide synthase Pks16 [Mycobacterium marinum M] gi|183177772|gb|ACC42882.1| polyketide synthase Pks16 [Mycobacterium marinum M] Length=544 Score = 252 bits (644), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 183/513 (36%), Positives = 258/513 (51%), Gaps = 36/513 (7%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 RH W EVH A +A L AVG++ VE+ QG W+ GA++++L P Sbjct 28 VRHTWGEVHERARQIAGGLAAAGVGPGDAVGVLAGAPVEIAPTAQGLWIRGASLTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTA-AHTNRSAT 146 + WA+ T T I + V+ ++A ++ G+ + A Sbjct 88 TPRTDLALWAEDTTTVVDMIEAKAVVISDPFMAAAPVLEERGIRVLTFEQLLASEPIDPV 147 Query 147 PVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDM 206 V + A++Q T+GSTG+P+ ++ + +NL + DA TDV SWLPL+HDM Sbjct 148 EVGEDELALMQLTSGSTGSPKAVQITHRNLFANLEAMYISAEYDAETDVMVSWLPLFHDM 207 Query 207 GLAFVLSAAL--AGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 G+ L+ + AG + + P F W + TMTAAPNFAY+L K R+ Sbjct 208 GMIGFLTVPMYFAGELVKVTPMD-FMRDTLLWAKLIDKYKGTMTAAPNFAYSLFAKRLRK 266 Query 265 VS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVP 321 + + DL +LR L+G EPV+ + EA APFG A+LP+YG+AE T AV Sbjct 267 QAKPGQFDLSSLRFALSGAEPVEPSDVEDLCEAGAPFGLRPQAILPAYGMAEITLAVAFS 326 Query 322 VPGIGLLADRV-IDGSGAHKHAV------------LGNPIPGMEVRISCGDQAAGNA--S 366 G GL+ D V D A + AV LG + G+E RI D GN S Sbjct 327 ECGAGLVVDEVDADLMAALRRAVPAAKGNTRRLASLGPLLQGIEARIVDAD---GNVLPS 383 Query 367 REIGEIEIRGASMMAGYLGQQPIDPDD----WFATGDLGY-LGAGGLVVCGRAKEVISIA 421 R +G IE+RG S+ GYL P W+ TGDLGY + G +VVCGR K+VI +A Sbjct 384 RGVGVIELRGESVTPGYLTMGGFIPAQDQLGWYDTGDLGYQMENGHVVVCGRVKDVIIMA 443 Query 422 GRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAE---FRGPDEA-NARAEL 477 GRNI+PT++E A +V GVR G VA+ +R VA E F P E ++ Sbjct 444 GRNIYPTDIERAAGRVEGVRPGCAVAVRLDAGHSRETFAVAVESNAFEDPAEVRRIEHQV 503 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PG++P+T SGKLRR Sbjct 504 AHEVVAEVDVRPRNVVVLGPGTIPKTPSGKLRR 536 >gi|158315222|ref|YP_001507730.1| long-chain-fatty-acid--CoA ligase [Frankia sp. EAN1pec] gi|158110627|gb|ABW12824.1| AMP-dependent synthetase and ligase [Frankia sp. EAN1pec] Length=562 Score = 252 bits (643), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 180/522 (35%), Positives = 260/522 (50%), Gaps = 46/522 (8%) Query 34 WPEVHGLAESVAAWLLDHD---RPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRG 90 W + AE VAAWL + V ++ P+ +V A+ W+AG +V+ P P R Sbjct 31 WSDFFVQAERVAAWLQAARGIGPSSRVVVLATPSKAMVTAVVAVWMAGGSVTCAPTPART 90 Query 91 ANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSAT---- 146 + + D T R +G VL Y ++ T GV + L+ A + Sbjct 91 VDLPTYVDQTGKRIAALGDPLVLLGAPYEELGETLATDGVRVDRLTDAVAAESAGAWKRP 150 Query 147 PVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDM 206 + + PA++Q T+G+T AP++ ++S G +++N+ + +R+ D SWLPL HDM Sbjct 151 EITPDDPAIVQFTSGTTAAPKSVLISHGNLVANIAAIRERIRHDEVHGRLLSWLPLSHDM 210 Query 207 GLAFVLSAALAG--APLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 GL L+ L + + ASP WL+ + AT+ P AY + G+ Sbjct 211 GLIGALAVQLTCGRCDVLFGTPADYLASPSSWLANAARYRATILLGPASAYAMAGRLLAV 270 Query 265 VSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPG 324 +DL +++V L GGEP++ + RF +A AP G D A LP+YGLAE+T A +P P Sbjct 271 GPRLDLSSIKVALCGGEPIEPAAIERFLDAAAPHGLDRSAFLPAYGLAEATLAAAMP-PT 329 Query 325 IGLLADRV---------------IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREI 369 GL D + + G+ + LG P+PG++VR+ + R + Sbjct 330 PGLRFDEIDADVFTQRRVAVPVTVPGAPVRRLVRLGPPLPGLKVRLVDPESGQPCPERSV 389 Query 370 GEIEIRGASMMAGYL--GQQPID-----------------PDDWFATGDLGYLGAGGLVV 410 GEI I G S+ +GYL +D D W ATGDLGYL G LVV Sbjct 390 GEIYISGESVTSGYLEGSDAELDRCSGAGEASEASGVRHVADGWLATGDLGYLVDGELVV 449 Query 411 CGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTG-DRSTRPGLVVAAEFR-GP 468 CGRAK++I I GRN+ P EVE AA+V GVR G VVA T D G+ VA E R G Sbjct 450 CGRAKDLIIIGGRNLHPEEVEEAAARVPGVRPGNVVAYPTARDSGAAEGMAVAVETRGGH 509 Query 469 DEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 +EA RA + V + G+ P V + PGS+P+T SGKL+R Sbjct 510 EEATIRARVTAAVLAAVGVRPVQVHVLPPGSIPKTPSGKLQR 551 >gi|120402066|ref|YP_951895.1| long-chain-fatty-acid--CoA ligase [Mycobacterium vanbaalenii PYR-1] gi|119954884|gb|ABM11889.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=544 Score = 251 bits (641), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 180/513 (36%), Positives = 266/513 (52%), Gaps = 38/513 (7%) Query 31 RHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGPV 88 RH W EVH A VA L AV ++ VE+ A QG W+ GA+V+++ P Sbjct 29 RHSWEEVHQRARRVAGGLAAAGVGPGDAVAMLAGAPVEIAPAAQGVWMRGASVTMVHQPT 88 Query 89 RGANDQRWADATLTRFLGIGVRTVLSQGSYLAR---LRSVDTAGVTIGDLSTAAHTNRSA 145 + RWA+ T I + V+ ++A L + +TI DL A + Sbjct 89 PRTDLVRWAEETTAVITMIDAKAVVISDPFMAAAPVLEGLGMTVLTIADLLAADRVDPVE 148 Query 146 TPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 T + + A++Q T+GSTG+P+ ++ +++N + D TDV SWLP +HD Sbjct 149 T--SDDDIALMQLTSGSTGSPKAVQITHANIVANADAMTAGCNFDIDTDVIVSWLPCFHD 206 Query 206 MGLAFVLSAALA-GAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARR 264 MG+ L+ + GA L F + W + TMTAAPNFAYNL+ + RR Sbjct 207 MGMTGYLTVPMYFGAELVKVTPMDFLSDILLWPRLIDKYRGTMTAAPNFAYNLLARRLRR 266 Query 265 VS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVP 321 + E DL +LR L+G E VD + +A APFG A++P+YG+AE+T AV+ Sbjct 267 QADPGEFDLSSLRWALSGAEQVDPLDVEDLCDAGAPFGLKPEAIVPAYGMAETTVAVSFS 326 Query 322 VPGIGLLAD-----------RVIDGSGAH--KHAVLGNPIPGMEVRISCGDQAAGNASRE 368 G G++ D R + + H + LG P+ G+E+R+ D A A R Sbjct 327 ECGGGMVVDEVDADLLAVLHRAVPATKGHTRRLVTLGRPLQGLELRVVDEDGAELPA-RG 385 Query 369 IGEIEIRGA------SMMAGYLGQQPIDPDDWFATGDLGYLG-AGGLVVCGRAKEVISIA 421 +G IE+RG + +AG++G Q D W+ TGD+GYL G +VVCGR K+VI +A Sbjct 386 VGVIEVRGEPVTKGYTTVAGFIGAQ--DDRGWYDTGDIGYLTEVGDVVVCGRLKDVIIMA 443 Query 422 GRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG-PDEANAR---AEL 477 GRNI+PT++E A +V GVR G VA+ +R VA E + DE R ++ Sbjct 444 GRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGRSRETFAVAVECKDFGDETQVRRVERQV 503 Query 478 IQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV ++PG++P+T SGKLRR Sbjct 504 AHEVFAEVDVRPRNVVVLAPGTIPKTPSGKLRR 536 >gi|145222525|ref|YP_001133203.1| long-chain-fatty-acid--CoA ligase [Mycobacterium gilvum PYR-GCK] gi|315442973|ref|YP_004075852.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|145215011|gb|ABP44415.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|315261276|gb|ADT98017.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=544 Score = 249 bits (637), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 180/512 (36%), Positives = 254/512 (50%), Gaps = 34/512 (6%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 RH W EVH A+ +A L AVG++ VE+ QG W+ GA++++L P Sbjct 28 VRHTWSEVHERAKRIAGGLAAAGVGLGDAVGVLAGFPVEIAPTAQGLWMRGASLTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGV---TIGDLSTAAHTNRS 144 + WA+ T+ I + V+ +L + ++ G+ TI DL A Sbjct 88 TPRTDLVMWAEDTMNVIGMIEAKAVIVSEPFLVAIPVLEEKGIKVLTITDL--LASEPIE 145 Query 145 ATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYH 204 V + A++Q T+GSTG+P+ ++ + SN + D DV SWLP +H Sbjct 146 PIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSNAEAMFIGAQYDVEKDVMVSWLPCFH 205 Query 205 DMGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYAR 263 DMG+ F+ GA L F W + TMTAAPNFAY L K R Sbjct 206 DMGMVGFLTIPMYFGAELVKVTPMDFLRDTLLWAKLIDKYKGTMTAAPNFAYALFAKRLR 265 Query 264 RVS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV 320 R + E DL LR L+G EPV+ + +A PFG D GA+LP+YG+AE+T AV+ Sbjct 266 RQAKPGEFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLDPGAILPAYGMAETTLAVSF 325 Query 321 PVPGIGLLAD-----------RVIDGSGAH--KHAVLGNPIPGMEVRISCGDQAAGNASR 367 G GL D R + S H + A LG + +E R+ D R Sbjct 326 SPCGAGLTVDEVDADLLAALRRAVPASKGHTKRLAELGPLLTDLEARV-IDDHGNLMPPR 384 Query 368 EIGEIEIRGASMMAGYL---GQQPI-DPDDWFATGDLGYLG-AGGLVVCGRAKEVISIAG 422 +G IE+RG + GY+ G P D W+ TGDLGY+ G +VVCGR K+VI +AG Sbjct 385 GVGVIELRGECVTPGYMTMGGFIPAQDEHGWYDTGDLGYITEEGNVVVCGRVKDVIIMAG 444 Query 423 RNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAE---FRGPDEA-NARAELI 478 RNI+PT++E A +V GVR G VA+ +R VA E ++ P E ++ Sbjct 445 RNIYPTDIERAAGRVEGVRPGCAVAVRLDAGHSRETFAVAVESNNWQDPVEVRRIEHQVA 504 Query 479 QRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PGS+P+TSSGKLRR Sbjct 505 HEVVAEVDVRPRNVVVLGPGSIPKTSSGKLRR 536 >gi|240169904|ref|ZP_04748563.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=544 Score = 249 bits (635), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 186/544 (35%), Positives = 273/544 (51%), Gaps = 42/544 (7%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWL----LDHDRPAA 56 MS + R+ + SA ++ + T + RH W EVH A +A L + H A Sbjct 1 MSRFTDKMFRNARQSAKGMVTGEPHTPV--RHTWGEVHERARRIAGGLAAVGVGHGD--A 56 Query 57 VGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQG 116 VG++ VE+ QG W+ GA++++L P + WA+ T T I + V+ Sbjct 57 VGVLAGAPVEIAPTAQGLWMRGASLTMLHQPTPRTDLALWAEDTTTVVDMIEAKAVIISD 116 Query 117 SYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGP--AVLQGTAGSTGAPRTAILSPG 174 ++A + G+ + + ++ P+ ++ A++Q T+GSTG+P+ ++ Sbjct 117 PFMAAAPVLQERGIKVLTVEQLLASD-PVDPIETDEDDLALMQLTSGSTGSPKAVQITHR 175 Query 175 AVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGL-AFVLSAALAGAPLWLAPTTAFTASP 233 + +NL + + TDV SWLPL+HDMG+ F+ G L F Sbjct 176 NLFANLEAMYISAEYNEDTDVMVSWLPLFHDMGMIGFLTVPMYFGGELVKVTPMDFMRDT 235 Query 234 FRWLSWLSDSGATMTAAPNFAYNLIGKYARRVS---EVDLGALRVTLNGGEPVDCDGLTR 290 W + G TMTAAPNFAY+L K R+ + + DL +LR L+G EPV+ + Sbjct 236 LLWAKLIDKYGGTMTAAPNFAYSLFAKRLRKQAKPGQFDLSSLRFALSGAEPVEPADVED 295 Query 291 FAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRV-IDGSGAHKHAV------ 343 +A APFG A+LP+YG+AE T AV G GL+ D V D A + AV Sbjct 296 LCQAGAPFGLRPQAILPAYGMAEITLAVAFSECGAGLVVDEVDADLLAALRRAVPATKGN 355 Query 344 ------LGNPIPGMEVRISCGDQAAGNA--SREIGEIEIRGASMMAGYL---GQQPI-DP 391 LG + G+E RI D GN R +G IE+RG S+ GY+ G P D Sbjct 356 TRRLASLGPLLQGIEARIVDED---GNILPPRGVGVIELRGESVTPGYITMGGFIPAQDA 412 Query 392 DDWFATGDLGY-LGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGT 450 W+ TGDLGY + G +VVCGR K+VI +AGRNI+PT++E A +V GVR G VA+ Sbjct 413 QGWYDTGDLGYRMENGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVEGVRPGCAVAVRL 472 Query 451 GDRSTRPGLVVAAE---FRGPDEA-NARAELIQRVASECGIVPSDVVFVSPGSLPRTSSG 506 +R VA E F P E ++ V +E + P +VV + PG++P+T SG Sbjct 473 DAGHSRETFAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSG 532 Query 507 KLRR 510 KLRR Sbjct 533 KLRR 536 >gi|169628233|ref|YP_001701882.1| long-chain-fatty-acid--CoA ligase [Mycobacterium abscessus ATCC 19977] gi|169240200|emb|CAM61228.1| Putative polyketide synthase Pks16 [Mycobacterium abscessus] Length=549 Score = 249 bits (635), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 186/519 (36%), Positives = 260/519 (51%), Gaps = 43/519 (8%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVG-LVGEPTVELVAAIQGAWLAGAAVSILPG 86 RH W +VH A+ VA L A+G LVG P VE+ AIQ W+ GA++++L Sbjct 28 VRHTWKQVHERAKQVAGGLAGAGLGPDDAIGMLVGMP-VEIAPAIQAVWMRGASLTMLHQ 86 Query 87 PVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSAT 146 P + WA+ TL IG + V+ + A ++ GV + + + Sbjct 87 PTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDAAAPVLEEKGVIVVHIKDLWDADPIEP 146 Query 147 PVASEGP-AVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHD 205 A E A++Q T+GSTG+P+ ++ + +N G+ DV SWLPL+HD Sbjct 147 LEADEDSVALMQLTSGSTGSPKAVKITHRNLYANAHGMYVASKYKPEIDVMVSWLPLFHD 206 Query 206 MGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYAR- 263 MG+ F+ GA L F W + TMTAAPNFAY+L K R Sbjct 207 MGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGRLIDKYKGTMTAAPNFAYSLFAKRLRN 266 Query 264 --RVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV- 320 + + DL LR L+G EPVD + +A PFGF A++P+YG+AE+ AV+ Sbjct 267 QAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAGKPFGFKPSAMVPAYGMAETALAVSFS 326 Query 321 PVPGIGLLADRVIDGS-------------GAHKH-AVLGNPIPGMEVRISCGDQAAGNAS 366 V GL+ D V D G +H A LG +PG+E R+ D A Sbjct 327 EVEASGLVVDEV-DADLLAALRRAVPATRGNLRHLATLGPLLPGIEARVVDEDLNVLPA- 384 Query 367 REIGEIEIRGASM------MAGYLGQQPIDPDDWFATGDLGYLGAGG-LVVCGRAKEVIS 419 R +G IE+RG S+ M G+L Q D + W+ TGDLGYL G +VVCGR K+VI Sbjct 385 RGVGVIELRGESVTPGYVTMGGFLAAQ--DENGWYNTGDLGYLTEKGHVVVCGRVKDVII 442 Query 420 IAGRNIFPTEVELVAAQVRGVREGAVVAL----GTGDRSTRPGLVVAAE---FRGPDEA- 471 +AGRNI+PT++E A +V GVR G VA+ G ++ R V E F PDE Sbjct 443 MAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPKNQRETFAVVVESNAFENPDEVR 502 Query 472 NARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 ++ V +E + P +VV + PGS+P+T SGKLRR Sbjct 503 RIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLRR 541 >gi|331694717|ref|YP_004330956.1| Long-chain-fatty-acid--(acyl-carrier-protein) ligase [Pseudonocardia dioxanivorans CB1190] gi|326949406|gb|AEA23103.1| Long-chain-fatty-acid--(acyl-carrier-protein) ligase [Pseudonocardia dioxanivorans CB1190] Length=556 Score = 248 bits (634), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 198/554 (36%), Positives = 277/554 (50%), Gaps = 49/554 (8%) Query 1 MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHD-------R 53 MS +L S SA ++ E S R PW EVH A ++A L D R Sbjct 1 MSRFLTMLLDSAARSAKGMVT--GEPSAPVRTPWSEVHTKARALAGALAAGDGSVPGLAR 58 Query 54 PAAVG-LVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTV 112 +AV L EP V + Q WL G +V++L P + WA T+ I + V Sbjct 59 GSAVAVLAAEPAV-IAPTAQAVWLLGGSVTMLHQPTARTDLAVWAADTVAVLGMIDAKLV 117 Query 113 LSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATP------VASEG-PAVLQGTAGSTGA 165 + + A + G+ LS ++ A P VA EG A+LQ T+GST Sbjct 118 VLGAPFDALAPVLAERGIAHRLLSDVDASD--AAPIVADEAVADEGDTALLQLTSGSTAE 175 Query 166 PRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLA-FVLSAALAGAPLWLA 224 P+ ++ + +N+RG+ DA DV SWLPL+HDMG+ F+ +AG L Sbjct 176 PKAVRITHANLYANIRGMIAAAQLDAGRDVMVSWLPLFHDMGMVGFLTIPMVAGIELVTV 235 Query 225 PTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSE--VDLGALRVTLNGGEP 282 F + P W +S ++TAAPNFAY+++ + R + +DL ++R LNG EP Sbjct 236 TPADFLSRPLLWAELISKYRGSVTAAPNFAYSVLARQLARAEDGSLDLSSMRFALNGAEP 295 Query 283 VDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHA 342 +D D + A FG +V+ +YG+AE+ V+ G++ D V D H Sbjct 296 IDPDAVDALTAAGKRFGLREDSVVCAYGMAETALGVSFAPCDTGMVVDHV-DAEQLELHR 354 Query 343 V--------------LGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYL---G 385 V LG P+PG+EVR+ GD RE+G +++RG S+ GYL G Sbjct 355 VAQPAIYGPSRRFPRLGPPLPGIEVRV-VGDDGRVLGEREVGILQLRGESVTPGYLTVDG 413 Query 386 QQPI-DPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGA 444 +P D D W TGD GYL +VVCGR K+VI + GRNI+PT++E AA VR G Sbjct 414 PRPAQDADGWLDTGDEGYLAGVEVVVCGRRKDVIIMGGRNIYPTDIERAAADAPDVRAGN 473 Query 445 VVA--LGTGDRSTRPGLVVAAEFR--GPDEANA--RAELIQRVASECGIVPSDVVFVSPG 498 VVA L G R +VA E R G +EA A R ++ RV + CG+ P+DVV + PG Sbjct 474 VVAVRLEAGAGRHRESFLVAVESRRAGDEEAEAVIRKDVTSRVVAACGVRPADVVVLRPG 533 Query 499 SLPRTSSGKLRRLA 512 +LP+T SGKLRR A Sbjct 534 TLPKTPSGKLRRSA 547 >gi|120405748|ref|YP_955577.1| long-chain-fatty-acid--CoA ligase [Mycobacterium vanbaalenii PYR-1] gi|119958566|gb|ABM15571.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=544 Score = 246 bits (629), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 179/512 (35%), Positives = 253/512 (50%), Gaps = 34/512 (6%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 RH W EVH A+ +A L AVG++ VE+ QG W+ GA++++L P Sbjct 28 VRHTWGEVHERAKRIAGGLAAAGVGLGDAVGVLAGFPVEIAPTAQGLWMRGASLTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGV---TIGDLSTAAHTNRS 144 + WA+ T+ I + V+ +L + ++ G+ T+ DL A Sbjct 88 TPRTDLVVWAEDTMNVIGMIEAKAVIVSEPFLVAIPVLEEKGIKVLTVTDLLAADPIE-- 145 Query 145 ATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYH 204 V + A++Q T+GSTG+P+ ++ + SN + D DV SWLP +H Sbjct 146 PIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSNAEAMFIGAQYDVEKDVMVSWLPCFH 205 Query 205 DMGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYAR 263 DMG+ F+ GA L F W + TMTAAPNFAY L K R Sbjct 206 DMGMVGFLTIPMYFGAELVKVTPLDFLRDTLLWAKLIDKYKGTMTAAPNFAYALFAKRLR 265 Query 264 RVS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV 320 R + E DL LR L+G EPV+ + +A PFG D GA+LP+YG+AE+T AV+ Sbjct 266 RQAKPGEFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLDPGAILPAYGMAETTLAVSF 325 Query 321 PVPGIGLLAD-----------RVIDGSGAH--KHAVLGNPIPGMEVRISCGDQAAGNASR 367 G GL D R + + H + A LG + +E R+ D R Sbjct 326 SPCGAGLTVDEVDADLLAALRRAVPATKGHTKRLAELGPLLTDLEARV-IDDHGNVMPPR 384 Query 368 EIGEIEIRGASMMAGYL---GQQPI-DPDDWFATGDLGYLG-AGGLVVCGRAKEVISIAG 422 +G IE+RG + GY+ G P D W+ TGDLGY+ G +VVCGR K+VI +AG Sbjct 385 GVGVIELRGECVTPGYMTMGGFIPAQDEHGWYDTGDLGYITEEGNVVVCGRVKDVIIMAG 444 Query 423 RNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG-PDEANAR---AELI 478 RNI+PT++E A +V GVR G VA+ +R VA E D A R ++ Sbjct 445 RNIYPTDIERAAGRVEGVRPGCAVAVRLDAGHSRETFAVAVESNNWQDPAEVRRIEHQVA 504 Query 479 QRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 V +E + P +VV + PGS+P+TSSGKLRR Sbjct 505 HEVVAEVDMRPRNVVVLGPGSIPKTSSGKLRR 536 >gi|183980208|ref|YP_001848499.1| polyketide synthase Pks16_1 [Mycobacterium marinum M] gi|183173534|gb|ACC38644.1| polyketide synthase Pks16_1 [Mycobacterium marinum M] Length=546 Score = 246 bits (628), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 187/511 (37%), Positives = 261/511 (52%), Gaps = 24/511 (4%) Query 33 PWPEVHGLAESVAAWLL-DHDRPAAVG--LVGEPTVELVAAIQGAWLAGAAVSILPGPVR 89 PW ++H L A L D P V L G P E+ +QGAW+ GAAV++L P Sbjct 35 PWSDIHHLGRRAAGALQRDGVTPGDVVAVLAGAPG-EIAPLVQGAWMCGAAVTMLHQPTH 93 Query 90 GANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVA 149 ++ Q WA T +G TV+ + + + G+ +LS + VA Sbjct 94 RSDLQAWAADTKKTLSMVGASTVVVGSPFQSAAQEFAKVGLRGLELSELLTADEGRIVVA 153 Query 150 SE-GPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGL 208 E PA LQ T+GSTG P+ ++ + +N R L D A+DV SWLPL+HDMG+ Sbjct 154 EEDSPAFLQLTSGSTGHPKAVSITYRNIEANGRALMAAASADVASDVVVSWLPLFHDMGM 213 Query 209 AFVLSAALAGAPLWLAPTTA-FTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSE 267 +L + + T A F P W ++ ++TAAPNFAY+L+ + RR + Sbjct 214 MGLLIIPMYEGMDAVHITPADFLNDPLLWAELITKHRGSITAAPNFAYSLLARRLRRAQD 273 Query 268 --VDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGI 325 DL +LR LNG E +D L R A A FG A++P+YG+AE+T A++V PG Sbjct 274 HAFDLSSLRFALNGAEGIDVATLERLATEGARFGLRRDAIVPAYGMAEATLAISVVRPGE 333 Query 326 GLLA-----DRV-IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASM 379 G D V G A +LG P+PG +VR+ D+ A EIGE+EIRG ++ Sbjct 334 GFRVCPPHPDLVAAQGEAAAPRVMLGPPVPGCDVRVVSEDRTV-LAPSEIGELEIRGDNV 392 Query 380 MAGY---LGQQP-IDPDDWFATGDLGYLGAGGL-VVCGRAKEVISIAGRNIFPTEVELVA 434 AGY G +P +D W ATGD+GYL G V+CGR K+++ I+GRN+ P ++E Sbjct 393 TAGYRTEAGFEPAVDAGGWLATGDVGYLTENGQPVICGRKKDILIISGRNVHPEDIERSV 452 Query 435 AQVRGVREGAVVALGTGDRSTRPGLVVAAE--FRGPD-EAN-ARAELIQRVASECGIVPS 490 + G+R G V A+ S G V+ AE D E+N R E+ RV G+ P Sbjct 453 VGIAGIRSGGVAAVRLATASASEGFVMVAESALHADDAESNRIRTEVADRVFVNLGVSPR 512 Query 491 DVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 V V G LP+TSSGKLRR L + D Sbjct 513 AVHVVPAGWLPKTSSGKLRRRQTSERLRLFD 543 >gi|254821214|ref|ZP_05226215.1| long-chain-fatty-acid--CoA ligase [Mycobacterium intracellulare ATCC 13950] Length=544 Score = 246 bits (627), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 176/512 (35%), Positives = 253/512 (50%), Gaps = 34/512 (6%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 RH W EVH A +A L AVG++ VE+ QG W+ GA++++L P Sbjct 28 VRHTWGEVHERARRIAGGLAAAGIGPGDAVGVLAGFPVEIAPTAQGLWMRGASLTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAG---VTIGDLSTAAHTNRS 144 + WA+ T+ I + V+ +L + ++ G VT+ DL TA + Sbjct 88 TPRTDLAVWAEDTMNVIGMIEAKAVVVSEPFLVAIPVLEEKGIKVVTVADLLTAEPID-- 145 Query 145 ATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYH 204 V + A++Q T+GSTG+P+ ++ + SN + D DV SWLP +H Sbjct 146 PVEVGEDALALMQLTSGSTGSPKAVQITHRNIYSNAEAMFIGAQYDVDKDVMVSWLPCFH 205 Query 205 DMGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYAR 263 DMG+ F+ GA L F W + TMTAAPNFAY L+ K R Sbjct 206 DMGMVGFLTIPMYFGAELVKVTPMDFLRDTLLWAKLIDKYKGTMTAAPNFAYALLAKRLR 265 Query 264 RVS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV 320 R + + DL LR L+G EPV+ + +A PFG +A A+LP+YG+AE+T AV+ Sbjct 266 RQAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLNASAILPAYGMAETTLAVSF 325 Query 321 PVPGIGLLADRV-------------IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASR 367 GL+ D V + A LG + +E RI + R Sbjct 326 SECNAGLVVDEVDADLLAALRRAVPATKGNTRRLATLGPLLQDLEARI-IDENGDVMPPR 384 Query 368 EIGEIEIRGASMMAGYLGQ----QPIDPDDWFATGDLGYLGA-GGLVVCGRAKEVISIAG 422 +G IE+RG S+ GYL D + W+ TGDLGYL G +VVCGR K+VI +AG Sbjct 385 GVGVIELRGESLTPGYLTMGGFISAQDENGWYDTGDLGYLTEEGHVVVCGRVKDVIIMAG 444 Query 423 RNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG-PDEANAR---AELI 478 RNI+PT++E A +V GVR G VA+ +R VA E D+A R ++ Sbjct 445 RNIYPTDIERAACRVEGVRPGCAVAVRLDAGHSRETFAVAVESNAFQDQAEVRRIEHQVA 504 Query 479 QRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 + V +E + P +VV + PG++P+T SGKLRR Sbjct 505 REVVAEVDVRPRNVVVLGPGTIPKTPSGKLRR 536 >gi|118619948|ref|YP_908280.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118572058|gb|ABL06809.1| polyketide synthase Pks16_1 [Mycobacterium ulcerans Agy99] Length=550 Score = 244 bits (623), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 186/511 (37%), Positives = 260/511 (51%), Gaps = 24/511 (4%) Query 33 PWPEVHGLAESVAAWLL-DHDRPAAVG--LVGEPTVELVAAIQGAWLAGAAVSILPGPVR 89 PW ++H L A L D P V L G P E+ +QGAW+ GAAV++L P Sbjct 39 PWSDIHHLGRRAAGALQRDGVTPGDVVAVLAGAPG-EIAPLVQGAWMCGAAVTMLHQPTH 97 Query 90 GANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVA 149 ++ Q WA T +G T + + + + G+ +LS + VA Sbjct 98 RSDLQAWAADTKKTLSMVGASTAVVGSPFQSAAQEFAKVGLRGLELSELLTADEGRIVVA 157 Query 150 SE-GPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGL 208 E PA LQ T+GSTG P+ ++ + +N R L D A+DV SWLPL+HDMG+ Sbjct 158 EEDSPAFLQLTSGSTGHPKAVSITYRNIEANGRALMAAASADVASDVVVSWLPLFHDMGM 217 Query 209 AFVLSAALAGAPLWLAPTTA-FTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSE 267 +L + + T A F P W ++ ++TAAPNFAY+L+ + RR + Sbjct 218 MGLLIIPMYEGMDAVHITPADFLNDPLLWAELITKHRGSITAAPNFAYSLLARRLRRAQD 277 Query 268 --VDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGI 325 DL +LR LNG E +D L R A A FG A++P+YG+AE+T A++V PG Sbjct 278 HAFDLSSLRFALNGAEGIDVATLERLATEGARFGLRRDAIVPAYGMAEATLAISVVRPGE 337 Query 326 GLLA-----DRV-IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASM 379 G D V G A +LG P+PG +VR+ D+ A EIGE+EIRG ++ Sbjct 338 GFRVCPPHPDLVAAQGEAAAPRVMLGPPVPGCDVRVVSEDRTV-LAPSEIGELEIRGDNV 396 Query 380 MAGY---LGQQP-IDPDDWFATGDLGYLGAGGL-VVCGRAKEVISIAGRNIFPTEVELVA 434 AGY G +P +D W ATGD+GYL G V+CGR K+++ I+GRN+ P ++E Sbjct 397 TAGYRTEAGFEPAVDAGGWLATGDVGYLAENGQPVICGRKKDILIISGRNVHPEDIERSV 456 Query 435 AQVRGVREGAVVALGTGDRSTRPGLVVAAE--FRGPD-EAN-ARAELIQRVASECGIVPS 490 + G+R G V A+ S G V+ AE D E+N R E+ RV G+ P Sbjct 457 VGIAGIRSGGVAAVRLATASASEGFVMVAESALHADDAESNRIRTEVADRVFVNLGVSPR 516 Query 491 DVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD 521 V V G LP+TSSGKLRR L + D Sbjct 517 AVHVVPAGWLPKTSSGKLRRRQTSERLRLFD 547 >gi|342861613|ref|ZP_08718259.1| long-chain-fatty-acid--CoA ligase [Mycobacterium colombiense CECT 3035] gi|342130747|gb|EGT84043.1| long-chain-fatty-acid--CoA ligase [Mycobacterium colombiense CECT 3035] Length=544 Score = 243 bits (619), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 174/512 (34%), Positives = 251/512 (50%), Gaps = 34/512 (6%) Query 30 CRHPWPEVHGLAESVAAWLLDHDRPA--AVGLVGEPTVELVAAIQGAWLAGAAVSILPGP 87 RH W EVH A +A L AVG++ VE+ QG W+ GA++++L P Sbjct 28 VRHTWGEVHERARRIAGGLAAAGIGPDDAVGVLAGYPVEIAPTAQGLWMRGASLTMLHQP 87 Query 88 VRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAG---VTIGDLSTAAHTNRS 144 + WA+ T+ I + V+ +L + ++ G VT+ DL A Sbjct 88 TPRTDLAVWAEDTMNVIGMIEAKAVVVSEPFLVAIPVLEEKGIKVVTVADLLAAEPIE-- 145 Query 145 ATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYH 204 V + A++Q T+GSTG+P+ ++ + SN + D DV SWLP +H Sbjct 146 PVEVGEDALALMQLTSGSTGSPKAVQITHRNIYSNAEAMFIGAQYDVTKDVMVSWLPCFH 205 Query 205 DMGLA-FVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYAR 263 DMG+ F+ GA L F W + TMTAAPNFAY L+ K R Sbjct 206 DMGMVGFLTIPMYFGAELVKVTPMDFLRDTLLWAKLIDKYKGTMTAAPNFAYALLAKRLR 265 Query 264 RVS---EVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV 320 R + + DL LR L+G EPV+ + +A PFG + A+LP+YG+AE+T AV+ Sbjct 266 RNAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLKSSAILPAYGMAETTLAVSF 325 Query 321 PVPGIGLLADRV-------------IDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASR 367 GL+ D V + A LG + +E RI + +R Sbjct 326 SECNAGLVVDEVDADLLAALRRAVPATKGNTRRLATLGPLLRDLEARI-IDENGDVMPAR 384 Query 368 EIGEIEIRGASMMAGYLGQ----QPIDPDDWFATGDLGYLGA-GGLVVCGRAKEVISIAG 422 +G IE+RG S+ GYL D + W+ TGDLGYL G +VVCGR K+VI +AG Sbjct 385 GVGVIELRGESLTPGYLTMGGFISAQDENGWYDTGDLGYLTEEGHVVVCGRVKDVIIMAG 444 Query 423 RNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG-PDEANAR---AELI 478 RNI+PT++E A +V GVR G VA+ +R VA E D+A R ++ Sbjct 445 RNIYPTDIERAACRVEGVRPGCAVAVRLDAGHSRETFAVAVESNAFQDQAEVRRIEHQVA 504 Query 479 QRVASECGIVPSDVVFVSPGSLPRTSSGKLRR 510 + V +E + P +VV + PG++P+T SGKLRR Sbjct 505 REVVAEVDVRPRNVVVLGPGTIPKTPSGKLRR 536 >gi|183984938|ref|YP_001853229.1| acyl-coenzyme A synthetase [Mycobacterium marinum M] gi|183178264|gb|ACC43374.1| acyl-coenzyme A synthetase [Mycobacterium marinum M] Length=549 Score = 242 bits (618), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 178/515 (35%), Positives = 262/515 (51%), Gaps = 40/515 (7%) Query 34 WPEVHGLAESVAAWLLDH--DRPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGA 91 W ++H A VA L R + V ++ ++ +QG W GAA+++L P A Sbjct 32 WRDIHQTAVRVAGRLSAEGVTRGSRVTVLAAGPEDVAPVVQGIWRLGAAMTMLQQPTSQA 91 Query 92 NDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTA-AHTNRSATPVAS 150 + W TL + R V+ +LA ++ AG I ++ + + P Sbjct 92 DLAGWHAGTLRALALLDTRWVVIGEPFLAAAETLRAAGYRIIEIGESWPELAATEEPTGE 151 Query 151 EGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGL-A 209 + A+ Q T+GSTG P+ ++ G + +++ + V D D+ SWLPL HDMGL A Sbjct 152 DDVALYQLTSGSTGDPKAVAITHGNLFADVAAMTAEVHLDPEVDITASWLPLSHDMGLIA 211 Query 210 FVLSAALAG-APLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEV 268 +++S AG +++ PT F SP +W+ L++ AT+TAAPNFAY++I +RR+S V Sbjct 212 YLISPMFAGNGAVYITPTE-FVVSPLKWMQILTERRATITAAPNFAYSII---SRRLSAV 267 Query 269 -----DLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTV-PV 322 DL ALR + G EP+D + FA FG A+ +YGLAE+T AV+ PV Sbjct 268 EDGTYDLSALRCVVTGAEPIDPATMAEFARQAGRFGLRHTALGAAYGLAEATVAVSFSPV 327 Query 323 PG--------IGLLADRVID------GSGAHKHAVLGNPIPGMEVRISCGDQAAGNASRE 368 + L +R + G + LG P+ G+EVRI D + R Sbjct 328 DNPLTTESVCVEELENRGLALPACSCGGPTKQFVTLGPPMSGVEVRIVAAD-GSNLPPRR 386 Query 369 IGEIEIRGASMMAGYLGQQ----PIDPDDWFATGDLGYLGAGG-LVVCGRAKEVISIAGR 423 +GEI I G ++ YL +DPD W TGDLGYL GG +VVCGR K VI +AGR Sbjct 387 MGEIAIAGDAVARHYLTMDGEVAAVDPDGWLFTGDLGYLTEGGEIVVCGRRKNVIIVAGR 446 Query 424 NIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRG----PDEANARAELIQ 479 NIFP ++E +AA V G+R G VVA G R + + AE D R ++ Q Sbjct 447 NIFPADIERLAASVHGIRRGGVVAFGVTLADRREEIRIVAETVADPSIEDGRELRRQIAQ 506 Query 480 RVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVR 514 V G+ P+ V+ V G +P+T+SGK+R + R Sbjct 507 NVRGATGLSPT-VLLVGKGKVPKTASGKIRHVMAR 540 Lambda K H 0.318 0.134 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1141106463692 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40