BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1353c
Length=261
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608493|ref|NP_215869.1| transcriptional regulatory protein ... 535 2e-150
gi|289749909|ref|ZP_06509287.1| transcriptional regulator [Mycob... 533 8e-150
gi|253799599|ref|YP_003032600.1| transcriptional regulator [Myco... 532 2e-149
gi|183983990|ref|YP_001852281.1| transcriptional regulatory prot... 410 7e-113
gi|118619100|ref|YP_907432.1| transcriptional regulatory protein... 410 1e-112
gi|240170890|ref|ZP_04749549.1| transcriptional regulatory prote... 405 3e-111
gi|41408492|ref|NP_961328.1| hypothetical protein MAP2394 [Mycob... 402 3e-110
gi|254823363|ref|ZP_05228364.1| hypothetical protein MintA_25769... 402 3e-110
gi|254774410|ref|ZP_05215926.1| hypothetical protein MaviaA2_070... 402 3e-110
gi|118463695|ref|YP_880820.1| TetR family transcriptional regula... 402 3e-110
gi|296170309|ref|ZP_06851900.1| TetR/AcrR family transcriptional... 400 1e-109
gi|342857974|ref|ZP_08714630.1| TetR family transcriptional regu... 399 3e-109
gi|254364248|ref|ZP_04980294.1| hypothetical transcriptional reg... 396 2e-108
gi|289753435|ref|ZP_06512813.1| transcriptional regulator [Mycob... 377 6e-103
gi|118472381|ref|YP_886577.1| TetR family transcriptional regula... 362 3e-98
gi|120402985|ref|YP_952814.1| TetR family transcriptional regula... 357 8e-97
gi|333992035|ref|YP_004524649.1| transcriptional regulator [Myco... 356 2e-96
gi|145224934|ref|YP_001135612.1| TetR family transcriptional reg... 342 4e-92
gi|108798738|ref|YP_638935.1| TetR family transcriptional regula... 337 9e-91
gi|118472163|ref|YP_886591.1| TetR family transcriptional regula... 216 2e-54
gi|169628599|ref|YP_001702248.1| putative HTH-type transcription... 204 1e-50
gi|262203723|ref|YP_003274931.1| TetR family transcriptional reg... 174 9e-42
gi|312197041|ref|YP_004017102.1| TetR family transcriptional reg... 129 4e-28
gi|86741285|ref|YP_481685.1| TetR family transcriptional regulat... 103 3e-20
gi|111219898|ref|YP_710692.1| TetR family transcriptional regula... 93.6 3e-17
gi|271963480|ref|YP_003337676.1| TetR family transcriptional reg... 77.8 2e-12
gi|336119466|ref|YP_004574243.1| TetR family transcriptional reg... 76.6 3e-12
gi|254386339|ref|ZP_05001646.1| transcriptional regulator [Strep... 76.3 5e-12
gi|294817429|ref|ZP_06776071.1| transcriptional regulator, TetR ... 75.1 9e-12
gi|345002701|ref|YP_004805555.1| TetR family transcriptional reg... 73.6 3e-11
gi|111223381|ref|YP_714175.1| TetR family transcriptional regula... 73.2 4e-11
gi|213969962|ref|ZP_03398095.1| transcriptional regulator, TetR ... 72.4 6e-11
gi|294633314|ref|ZP_06711873.1| tetracycline repressor protein c... 72.0 8e-11
gi|331014441|gb|EGH94497.1| transcriptional regulator, TetR fami... 72.0 8e-11
gi|28869835|ref|NP_792454.1| TetR family transcriptional regulat... 72.0 9e-11
gi|42509|emb|CAA24908.1| unnamed protein product [uncultured bac... 71.6 9e-11
gi|66045614|ref|YP_235455.1| transcriptional repressor TetR [Pse... 71.6 9e-11
gi|111020021|ref|YP_702993.1| TetR family transcriptional regula... 71.6 1e-10
gi|302752605|gb|ADL67001.1| synthetic iM2 transcription activato... 71.6 1e-10
gi|331694208|ref|YP_004330447.1| regulatory protein TetR [Pseudo... 71.6 1e-10
gi|157835403|pdb|2NS7|A Chain A, How An In Vitro Selected Peptid... 71.6 1e-10
gi|196968521|gb|ACG80832.1| rtTA-M2s* [Expression vector pDM310]... 71.2 1e-10
gi|84795125|gb|ABC65842.1| rtTA-M2.alt [Expression vector peTetO... 71.2 1e-10
gi|330467812|ref|YP_004405555.1| TetR family transcriptional reg... 71.2 1e-10
gi|330368227|gb|AEC11551.1| doxycycline-activated transcriptiona... 71.2 1e-10
gi|183221843|ref|YP_001839839.1| TetR family transcriptional reg... 71.2 1e-10
gi|157313363|gb|AAZ16157.2| adapted tetracycline-dependent trans... 70.9 2e-10
gi|313652102|gb|ADR71685.1| rtTA3 [Retroviral Tet-shRNA expressi... 70.9 2e-10
gi|196968542|gb|ACG80850.1| tTA [Expression vector pDM309] 70.9 2e-10
gi|300823293|ref|ZP_07103425.1| tetracycline repressor protein c... 70.5 2e-10
>gi|15608493|ref|NP_215869.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15840808|ref|NP_335845.1| TetR/AcrR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31792549|ref|NP_855042.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97]
65 more sequence titles
Length=261
Score = 535 bits (1379), Expect = 2e-150, Method: Compositional matrix adjust.
Identities = 261/261 (100%), Positives = 261/261 (100%), Gaps = 0/261 (0%)
Query 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK 60
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK
Sbjct 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK 60
Query 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP 120
DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
Sbjct 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP 120
Query 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA
Sbjct 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
Query 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
Sbjct 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
Query 241 RRPTATADAPTPGARAKAVAR 261
RRPTATADAPTPGARAKAVAR
Sbjct 241 RRPTATADAPTPGARAKAVAR 261
>gi|289749909|ref|ZP_06509287.1| transcriptional regulator [Mycobacterium tuberculosis T92]
gi|289690496|gb|EFD57925.1| transcriptional regulator [Mycobacterium tuberculosis T92]
Length=261
Score = 533 bits (1374), Expect = 8e-150, Method: Compositional matrix adjust.
Identities = 260/261 (99%), Positives = 260/261 (99%), Gaps = 0/261 (0%)
Query 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK 60
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK
Sbjct 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK 60
Query 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP 120
DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHA SMRKTFADNPVLCDLILIRAALSP
Sbjct 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHASSMRKTFADNPVLCDLILIRAALSP 120
Query 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA
Sbjct 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
Query 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
Sbjct 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
Query 241 RRPTATADAPTPGARAKAVAR 261
RRPTATADAPTPGARAKAVAR
Sbjct 241 RRPTATADAPTPGARAKAVAR 261
>gi|253799599|ref|YP_003032600.1| transcriptional regulator [Mycobacterium tuberculosis KZN 1435]
gi|289554855|ref|ZP_06444065.1| transcriptional regulator [Mycobacterium tuberculosis KZN 605]
gi|297633905|ref|ZP_06951685.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN 4207]
6 more sequence titles
Length=261
Score = 532 bits (1371), Expect = 2e-149, Method: Compositional matrix adjust.
Identities = 260/261 (99%), Positives = 260/261 (99%), Gaps = 0/261 (0%)
Query 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKK 60
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHL VGVTSIYWYFRKK
Sbjct 1 MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLRVGVTSIYWYFRKK 60
Query 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP 120
DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
Sbjct 61 DDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP 120
Query 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA
Sbjct 121 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSA 180
Query 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV
Sbjct 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
Query 241 RRPTATADAPTPGARAKAVAR 261
RRPTATADAPTPGARAKAVAR
Sbjct 241 RRPTATADAPTPGARAKAVAR 261
>gi|183983990|ref|YP_001852281.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183177316|gb|ACC42426.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=267
Score = 410 bits (1055), Expect = 7e-113, Method: Compositional matrix adjust.
Identities = 199/255 (79%), Positives = 218/255 (86%), Gaps = 1/255 (0%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
KRQRR+RGSINP+DIISGAFELA+QVSIDNLSMP+LGKHLGVGVTSIYWYFRKKDDLLNA
Sbjct 14 KRQRRERGSINPDDIISGAFELAEQVSIDNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNA 73
Query 67 MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLG 126
MTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIR+ALSPK ARLG
Sbjct 74 MTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRSALSPKAARLG 133
Query 127 AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA 186
AQEME+AIANLV AGLS EDAFD Y+AVS+HVRGSVVL RL K+QSA SGP AIE +
Sbjct 134 AQEMERAIANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIEDAMN 193
Query 187 IDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTAT 246
IDP TTPLLA +G+GHRI PDE NFEYGL+CILDHAGRLI++ +KAA + A RP
Sbjct 194 IDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAKAA-KSAPSRPRKA 252
Query 247 ADAPTPGARAKAVAR 261
A P P RAKA R
Sbjct 253 AKPPAPRTRAKATTR 267
>gi|118619100|ref|YP_907432.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|118571210|gb|ABL05961.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=267
Score = 410 bits (1054), Expect = 1e-112, Method: Compositional matrix adjust.
Identities = 198/255 (78%), Positives = 218/255 (86%), Gaps = 1/255 (0%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
KRQRR+RGSINP+DIISGAFELA+QVSIDNLSMP+LGKHLGVGVTSIYWYFRKKDDLLNA
Sbjct 14 KRQRRERGSINPDDIISGAFELAEQVSIDNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNA 73
Query 67 MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLG 126
MTDRALSKYVFATPY+E DWRETLRNHAR MRKTF NP+LCDLILIR+ALSPKTARLG
Sbjct 74 MTDRALSKYVFATPYVEGSDWRETLRNHARLMRKTFMSNPILCDLILIRSALSPKTARLG 133
Query 127 AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA 186
AQ+ME+AIANLV AGLS EDAFD Y+AVS+HVRGSVVL RL K+QSA SGP AIE +
Sbjct 134 AQKMERAIANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIEDAMN 193
Query 187 IDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTAT 246
IDP TTPLLA +G+GHRI PDE NFEYGL+CILDHAGRLI++ +KAA + A RP
Sbjct 194 IDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAKAA-KSAPSRPRKA 252
Query 247 ADAPTPGARAKAVAR 261
A P P RAKA R
Sbjct 253 AKPPAPRTRAKATTR 267
>gi|240170890|ref|ZP_04749549.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=265
Score = 405 bits (1041), Expect = 3e-111, Method: Compositional matrix adjust.
Identities = 196/255 (77%), Positives = 216/255 (85%), Gaps = 0/255 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII+GAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATADKRQRRERGSINPDDIITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIR+ALSP+
Sbjct 64 DLLNAMTDRALSKYVFATPYVEADDWRETLRNHARLMRKTFMGNPILCDLILIRSALSPR 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
ARLGAQEME+AIANLV AGLS EDAFD Y+AVS+HVRGSVVL RL+ K QSA SGP A+
Sbjct 124 AARLGAQEMERAIANLVQAGLSPEDAFDTYAAVSLHVRGSVVLHRLNEKHQSADSGPRAL 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVR 241
E + IDP TTPL+A TG+GHRI PDE NFEYGL CILDHAGRLIE+ KAA + +
Sbjct 184 EDAMEIDPQTTPLIARVTGKGHRIATPDEANFEYGLNCILDHAGRLIEERPKAAKPPSPQ 243
Query 242 RPTATADAPTPGARA 256
R TA + AP RA
Sbjct 244 RKTAKSSAPRKRTRA 258
>gi|41408492|ref|NP_961328.1| hypothetical protein MAP2394 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396848|gb|AAS04711.1| hypothetical protein MAP_2394 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=268
Score = 402 bits (1033), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 197/249 (80%), Positives = 211/249 (85%), Gaps = 1/249 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII+GAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 10 QATADKRQRRERGSINPDDIITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 69
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 70 DLLNAMTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPK 129
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
ARLGAQEMEKA+ANLV AGLS EDAFD YSA+SVHVRGSVVL RL K+QS+ GP AI
Sbjct 130 AARLGAQEMEKAVANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAI 189
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKA-AGEVAV 240
E VAIDP TPLLA T GHRIGAPDETNFEYGL CILDHA RLIE+ A AG
Sbjct 190 EDAVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEEGKGAKAGPSRQ 249
Query 241 RRPTATADA 249
R+P ++ A
Sbjct 250 RKPAKSSAA 258
>gi|254823363|ref|ZP_05228364.1| hypothetical protein MintA_25769 [Mycobacterium intracellulare
ATCC 13950]
Length=261
Score = 402 bits (1032), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 193/248 (78%), Positives = 211/248 (86%), Gaps = 0/248 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DIISGAFELA++VSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATADKRQRRERGSINPDDIISGAFELAEEVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 64 DLLNAMTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPK 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
AR+GAQEMEKA++NLV AGLS EDAFD YSAVSVHVRGSVVL RL K+QS+ GP AI
Sbjct 124 AARMGAQEMEKAVSNLVEAGLSPEDAFDTYSAVSVHVRGSVVLQRLYEKNQSSDIGPRAI 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVR 241
E VAIDP TPLL+ T GHRIGAPDETNFEYGL CILDHA RLI++S+ A G+
Sbjct 184 EDAVAIDPEKTPLLSQVTRIGHRIGAPDETNFEYGLTCILDHASRLIDESNAAKGKAGAS 243
Query 242 RPTATADA 249
R ++ A
Sbjct 244 RQRKSSTA 251
>gi|254774410|ref|ZP_05215926.1| hypothetical protein MaviaA2_07035 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=267
Score = 402 bits (1032), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 197/249 (80%), Positives = 211/249 (85%), Gaps = 1/249 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII+GAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 9 QATADKRQRRERGSINPDDIITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 68
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 69 DLLNAMTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPK 128
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
ARLGAQEMEKA+ANLV AGLS EDAFD YSA+SVHVRGSVVL RL K+QS+ GP AI
Sbjct 129 AARLGAQEMEKAVANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAI 188
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKA-AGEVAV 240
E VAIDP TPLLA T GHRIGAPDETNFEYGL CILDHA RLIE+ A AG
Sbjct 189 EDAVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEEGKGAKAGPSRQ 248
Query 241 RRPTATADA 249
R+P ++ A
Sbjct 249 RKPAKSSAA 257
>gi|118463695|ref|YP_880820.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118164982|gb|ABK65879.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
gi|336461067|gb|EGO39947.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=262
Score = 402 bits (1032), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 197/249 (80%), Positives = 211/249 (85%), Gaps = 1/249 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII+GAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATADKRQRRERGSINPDDIITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 64 DLLNAMTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPK 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
ARLGAQEMEKA+ANLV AGLS EDAFD YSA+SVHVRGSVVL RL K+QS+ GP AI
Sbjct 124 AARLGAQEMEKAVANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAI 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKA-AGEVAV 240
E VAIDP TPLLA T GHRIGAPDETNFEYGL CILDHA RLIE+ A AG
Sbjct 184 EDAVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEEGKGAKAGPSRQ 243
Query 241 RRPTATADA 249
R+P ++ A
Sbjct 244 RKPAKSSAA 252
>gi|296170309|ref|ZP_06851900.1| TetR/AcrR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295895032|gb|EFG74751.1| TetR/AcrR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=270
Score = 400 bits (1028), Expect = 1e-109, Method: Compositional matrix adjust.
Identities = 200/260 (77%), Positives = 214/260 (83%), Gaps = 1/260 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DIISGAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 9 QATADKRQRRERGSINPDDIISGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 68
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETLRNHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 69 DLLNAMTDRALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPK 128
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
ARLGA+EMEKAIANLV AGLS EDAFD YSAVSVHVRGSVVL RL K+QS+ G AI
Sbjct 129 AARLGAEEMEKAIANLVEAGLSPEDAFDTYSAVSVHVRGSVVLQRLYEKNQSSDEGARAI 188
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKA-AGEVAV 240
E VAIDP TPLLA + GHRIGAPDETNFEYGL CILDHA LIE+ ++ G+ A
Sbjct 189 EDAVAIDPEKTPLLAQVSRIGHRIGAPDETNFEYGLGCILDHASWLIEEGKRSKGGKAAP 248
Query 241 RRPTATADAPTPGARAKAVA 260
R A +P AR KA A
Sbjct 249 SRQRKAAKSPASRARTKAPA 268
>gi|342857974|ref|ZP_08714630.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342135307|gb|EGT88473.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=262
Score = 399 bits (1024), Expect = 3e-109, Method: Compositional matrix adjust.
Identities = 197/250 (79%), Positives = 212/250 (85%), Gaps = 6/250 (2%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DIISGAFELA+QVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATADKRQRRERGSINPDDIISGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRALSKYVFATPY+EA DWRETL NHAR MRKTF NP+LCDLILIRAALSPK
Sbjct 64 DLLNAMTDRALSKYVFATPYVEASDWRETLANHARLMRKTFMGNPILCDLILIRAALSPK 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
AR+GAQEMEKA++NLV AGLS EDAFD YSA+SVHVRGSVVL RL K+QS+ GP AI
Sbjct 124 AARMGAQEMEKAVSNLVEAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDIGPRAI 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQS-----SKAAG 236
E V+IDP TPLLA T GHRIGAPDETNFEYGL CILDHA RLI++S SKAA
Sbjct 184 EDAVSIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIDESKGPKASKAAP 243
Query 237 EVAVRRPTAT 246
R+PTAT
Sbjct 244 SRQ-RKPTAT 252
>gi|254364248|ref|ZP_04980294.1| hypothetical transcriptional regulatory protein [Mycobacterium
tuberculosis str. Haarlem]
gi|289569366|ref|ZP_06449593.1| transcriptional regulator [Mycobacterium tuberculosis T17]
gi|134149762|gb|EBA41807.1| hypothetical transcriptional regulatory protein [Mycobacterium
tuberculosis str. Haarlem]
gi|289543120|gb|EFD46768.1| transcriptional regulator [Mycobacterium tuberculosis T17]
Length=195
Score = 396 bits (1017), Expect = 2e-108, Method: Compositional matrix adjust.
Identities = 195/195 (100%), Positives = 195/195 (100%), Gaps = 0/195 (0%)
Query 67 MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLG 126
MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLG
Sbjct 1 MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLG 60
Query 127 AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA 186
AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA
Sbjct 61 AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA 120
Query 187 IDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTAT 246
IDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTAT
Sbjct 121 IDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTAT 180
Query 247 ADAPTPGARAKAVAR 261
ADAPTPGARAKAVAR
Sbjct 181 ADAPTPGARAKAVAR 195
>gi|289753435|ref|ZP_06512813.1| transcriptional regulator [Mycobacterium tuberculosis EAS054]
gi|289694022|gb|EFD61451.1| transcriptional regulator [Mycobacterium tuberculosis EAS054]
Length=203
Score = 377 bits (969), Expect = 6e-103, Method: Compositional matrix adjust.
Identities = 186/191 (98%), Positives = 188/191 (99%), Gaps = 0/191 (0%)
Query 71 ALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEM 130
A ++ FATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEM
Sbjct 13 AAARSAFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEM 72
Query 131 EKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPA 190
EKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPA
Sbjct 73 EKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPA 132
Query 191 TTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAP 250
TTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAP
Sbjct 133 TTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAP 192
Query 251 TPGARAKAVAR 261
TPGARAKAVAR
Sbjct 193 TPGARAKAVAR 203
>gi|118472381|ref|YP_886577.1| TetR family transcriptional regulator [Mycobacterium smegmatis
str. MC2 155]
gi|118173668|gb|ABK74564.1| transcriptional regulator, TetR family protein [Mycobacterium
smegmatis str. MC2 155]
Length=245
Score = 362 bits (929), Expect = 3e-98, Method: Compositional matrix adjust.
Identities = 170/229 (75%), Positives = 191/229 (84%), Gaps = 0/229 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q KRQRR+RGSINPEDII GAFELA++VSIDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QPAAEKRQRRERGSINPEDIIKGAFELAEKVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRAL ++V ATPY+EA DWRE+L NHAR+MRK F NP+LCDLILIR+ALSP+
Sbjct 64 DLLNAMTDRALREFVVATPYVEAKDWRESLANHARTMRKAFMGNPILCDLILIRSALSPR 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
AR+G QE+E AIA LV AGLS+EDAFD YSAVSVHVRGSVVL RL K+++ + P
Sbjct 124 AARVGVQEVESAIAGLVEAGLSVEDAFDTYSAVSVHVRGSVVLHRLYEKNRANDNAPGDF 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQ 230
E + IDP TTPLLA T GHRIGA DE NFEYGL+CILDHA RLIE+
Sbjct 184 EEAMVIDPETTPLLAQVTSEGHRIGAADEQNFEYGLKCILDHAARLIEE 232
>gi|120402985|ref|YP_952814.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119955803|gb|ABM12808.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=250
Score = 357 bits (917), Expect = 8e-97, Method: Compositional matrix adjust.
Identities = 171/244 (71%), Positives = 197/244 (81%), Gaps = 0/244 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII GAFELA+QV IDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATAEKRQRRERGSINPDDIIKGAFELAEQVGIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRAL +Y FATPY+EA DWRETL NHARSMR+TF NP+LCDLILIR+ALSP+
Sbjct 64 DLLNAMTDRALRQYAFATPYVEAKDWRETLANHARSMRQTFNGNPILCDLILIRSALSPR 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
A+LG QE+E+AI +LV AGLS EDAFD YSA+SVHVRGSVVL RL K+ + G I
Sbjct 124 AAKLGVQEVERAIGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGEDGHGDI 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVR 241
+ + IDP + PLLA T +GH + A D+ NFEYGLECILDHA RLIEQ++K A +
Sbjct 184 DDTMTIDPESAPLLAAVTQKGHHLSASDDRNFEYGLECILDHAARLIEQNAKPARKATPA 243
Query 242 RPTA 245
+ TA
Sbjct 244 KSTA 247
>gi|333992035|ref|YP_004524649.1| transcriptional regulator [Mycobacterium sp. JDM601]
gi|333488003|gb|AEF37395.1| transcriptional regulatory protein [Mycobacterium sp. JDM601]
Length=250
Score = 356 bits (914), Expect = 2e-96, Method: Compositional matrix adjust.
Identities = 174/249 (70%), Positives = 201/249 (81%), Gaps = 6/249 (2%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q KRQRR+RGSINP+DII GAFELA+Q+ +DNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QPVAEKRQRRERGSINPDDIIDGAFELAEQIGVDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMT RAL +YVFATPY++A DWR+TLRNHA +MR TF NP+LCDLILIRAALSP+
Sbjct 64 DLLNAMTSRALRQYVFATPYVQAKDWRQTLRNHAHTMRTTFLGNPILCDLILIRAALSPR 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQ-SAGSGPSA 180
A+LG QE+E+AIA LV AGLS +DAFDIYSA+S+H+RGSVVL RL K++ S GPS
Sbjct 124 AAQLGVQEVERAIAGLVEAGLSPQDAFDIYSAISLHIRGSVVLRRLYEKNRASDAEGPSD 183
Query 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAV 240
E + IDP TPLLA T +GHRIGA D+ NF+YGL+CILD A RLIEQ+SK A
Sbjct 184 FEEAMVIDPEATPLLAQTTRQGHRIGAADDANFDYGLDCILDQAERLIEQNSKPA----- 238
Query 241 RRPTATADA 249
RR TA A A
Sbjct 239 RRRTAPASA 247
>gi|145224934|ref|YP_001135612.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|315445265|ref|YP_004078144.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
gi|145217420|gb|ABP46824.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
gi|315263568|gb|ADU00310.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=244
Score = 342 bits (877), Expect = 4e-92, Method: Compositional matrix adjust.
Identities = 163/230 (71%), Positives = 191/230 (84%), Gaps = 0/230 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINP+DII GAFELA+QV IDNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATAEKRQRRERGSINPDDIIKGAFELAEQVGIDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAMTDRAL +Y FATPY+EA DWRETL NHAR+MRKTF NP+LCDLILIR+ALSP+
Sbjct 64 DLLNAMTDRALRQYAFATPYVEARDWRETLANHARTMRKTFNGNPILCDLILIRSALSPR 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
A++G Q++EKAI +LV AGLS EDAFD YSA+SVHVRGSVVL RL K+ + G I
Sbjct 124 AAKVGVQQVEKAIGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGDDGHGDI 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQS 231
+ +AIDP T PLLA T +GH + A D+ NFE+GL+CIL++A RLIE++
Sbjct 184 DDTMAIDPETAPLLAAVTQKGHHLSASDDRNFEFGLDCILENAARLIEKA 233
>gi|108798738|ref|YP_638935.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119867856|ref|YP_937808.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|126434341|ref|YP_001070032.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|108769157|gb|ABG07879.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119693945|gb|ABL91018.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
gi|126234141|gb|ABN97541.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=250
Score = 337 bits (864), Expect = 9e-91, Method: Compositional matrix adjust.
Identities = 158/246 (65%), Positives = 189/246 (77%), Gaps = 0/246 (0%)
Query 2 QTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKD 61
Q T KRQRR+RGSINPEDII GAFELA++VS+DNLSMPLLGKHLGVGVTSIYWYFRKKD
Sbjct 4 QATAEKRQRRERGSINPEDIIKGAFELAEEVSVDNLSMPLLGKHLGVGVTSIYWYFRKKD 63
Query 62 DLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPK 121
DLLNAM DRAL + F PY++A +WRE+L NHA +MRKTF +P+LCDL+LIR ALS K
Sbjct 64 DLLNAMADRALRQIAFEAPYVDAANWRESLHNHAHNMRKTFLASPILCDLVLIRGALSTK 123
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI 181
RLG +++E A++ LV AGLS EDAFD YSAVSVHVRGSVVL RL K++S S +
Sbjct 124 ALRLGLEQIEAAVSGLVGAGLSPEDAFDTYSAVSVHVRGSVVLARLYEKTRSLESSEFRL 183
Query 182 EHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVR 241
+ IDP +TPL+A + +GH +G P++ NFEYGL CILDHA RLIEQ A A R
Sbjct 184 DDSATIDPESTPLMAELSAKGHHVGVPNDMNFEYGLNCILDHAARLIEQQDTTAKPAAAR 243
Query 242 RPTATA 247
R A++
Sbjct 244 RKNASS 249
>gi|118472163|ref|YP_886591.1| TetR family transcriptional regulator [Mycobacterium smegmatis
str. MC2 155]
gi|118173450|gb|ABK74346.1| transcriptional regulator, TetR family protein [Mycobacterium
smegmatis str. MC2 155]
Length=246
Score = 216 bits (551), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 113/214 (53%), Positives = 144/214 (68%), Gaps = 4/214 (1%)
Query 15 SINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSK 74
SI ++I+SGAFE+A++VS+DNLSMP L KHL VGVTSIYWYFR+KDDLL+AMT+ AL +
Sbjct 17 SITVDEILSGAFEVAREVSVDNLSMPQLAKHLDVGVTSIYWYFRRKDDLLDAMTELALRE 76
Query 75 YVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAI 134
Y F I+AG WRE+LR HA MR T NP+LCDLILIR AR +++E+ +
Sbjct 77 YDFGVSSIDAGSWRESLRAHAHRMRDTIQQNPILCDLILIRGTGGTPAARHALEKIEQPV 136
Query 135 ANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH-PVAIDPATTP 193
A LV AGLS + A YSA+ V VR S VL RL + A + P +H IDP T P
Sbjct 137 AALVQAGLSPQQAVQTYSAIQVLVRSSAVLHRLQNR---ASTVPLPRDHWQQVIDPQTMP 193
Query 194 LLAHATGRGHRIGAPDETNFEYGLECILDHAGRL 227
L++ TG G+RIGA D NF++ L+ IL+ A L
Sbjct 194 LISSLTGDGYRIGAADTANFDHILDSILERAEHL 227
>gi|169628599|ref|YP_001702248.1| putative HTH-type transcriptional regulator [Mycobacterium abscessus
ATCC 19977]
gi|169240566|emb|CAM61594.1| Putative HTH-type transcriptional regulator [Mycobacterium abscessus]
Length=250
Score = 204 bits (519), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 102/227 (45%), Positives = 145/227 (64%), Gaps = 10/227 (4%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
KR+RR+RGSI EDII+GAFELA+++ I LSMPLL KHL VGVTSIYWYFRKK +LL+A
Sbjct 23 KRERRRRGSITAEDIIAGAFELAEEIGISGLSMPLLAKHLDVGVTSIYWYFRKKGELLDA 82
Query 67 MTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAA-LSPKTARL 125
MTDRA +Y FA P++ W++ LR+H MR+ F + PVL +LIL+R + LS + +
Sbjct 83 MTDRATKQYHFAAPFVGDETWQDALRSHTHRMREAFRERPVLVELILMRTSELSSEALQA 142
Query 126 GAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPV 185
Q +E + L+ G S ++A D+Y A+S+H+RG VVL+ + ++G S +
Sbjct 143 SIQNLESLVRTLIGVGFSPDNALDVYFALSLHIRGVVVLEHMDTVMPASGEARSLV---- 198
Query 186 AIDPATT--PLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQ 230
P+ T P L RGH I + NF++ +E I++ A L+ Q
Sbjct 199 ---PSATLAPTLHELASRGHSIATISDANFDFTVEAIIERAENLLAQ 242
>gi|262203723|ref|YP_003274931.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262087070|gb|ACY23038.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=231
Score = 174 bits (442), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 93/222 (42%), Positives = 134/222 (61%), Gaps = 11/222 (4%)
Query 10 RRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTD 69
RR RGSI+ E+II+GAF++A +VS+ SMP+L KHLGVGVTSIYWYFRKK+DLL+AM D
Sbjct 11 RRARGSISAEEIIAGAFDVAGRVSLSEFSMPMLAKHLGVGVTSIYWYFRKKEDLLDAMAD 70
Query 70 RALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTA-----R 124
+A +Y ATP+I A +W++ LR H R M + F PVL +L L+R P +A +
Sbjct 71 KANEEYHAATPFIGADNWQDGLRRHFRRMHQAFRTQPVLVELTLLRP--YPHSADRTSMQ 128
Query 125 LGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHP 184
A +++ +A +V AG + E A +IY ++ HV G+ +++ + G P +
Sbjct 129 ATAAKLDSMVAAMVGAGFTAEQALEIYLSLLAHVCGAAMVEHQGIFATYDGGLPRGADET 188
Query 185 VAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGR 226
+ PLLA +GHRI ++ FE+ E IL A R
Sbjct 189 A----SAVPLLAELAAKGHRIDNVEDATFEFTFEAILAQAER 226
>gi|312197041|ref|YP_004017102.1| TetR family transcriptional regulator [Frankia sp. EuI1c]
gi|311228377|gb|ADP81232.1| regulatory protein TetR [Frankia sp. EuI1c]
Length=237
Score = 129 bits (324), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 78/227 (35%), Positives = 127/227 (56%), Gaps = 13/227 (5%)
Query 14 GSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALS 73
GSI+ ++I+ GA+E+A++VS+D LSM L + LGVGVTSIYWYFRKK+DLL+AMT+ A +
Sbjct 18 GSISADEIVRGAYEIAREVSLDQLSMSTLSERLGVGVTSIYWYFRKKEDLLHAMTEVAAA 77
Query 74 KYVFATP-YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAA-LSPKTARLGAQEME 131
P + + W L ++ + R+ ++ VL DL+L R + S +T +E
Sbjct 78 NLAERMPQFARSVPWPTMLHDYFTAYRRIHQEDEVLSDLLLARVSTYSRQTTTQVFLPVE 137
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAI----EHPVAI 187
+ +L AG S E A I++ +S + RG++V R+ G +AI H +A
Sbjct 138 AIVEHLTDAGFSPELALQIFNTISTYTRGAIVYKRI------LGLNAAAILDERRHRMA- 190
Query 188 DPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKA 234
D PLL GH + + +FE+ L C++ +++ +++ A
Sbjct 191 DWTVMPLLEGLVAAGHSLTGTTDDDFEFALSCLISGFEQILARNASA 237
>gi|86741285|ref|YP_481685.1| TetR family transcriptional regulator [Frankia sp. CcI3]
gi|86568147|gb|ABD11956.1| transcriptional regulator, TetR family [Frankia sp. CcI3]
Length=221
Score = 103 bits (256), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 56/160 (35%), Positives = 85/160 (54%), Gaps = 1/160 (0%)
Query 8 RQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAM 67
R RR RGSIN I++G FE + +D LSMP L +L VGVTSIYWYF+ K +LL+AM
Sbjct 13 RSRRARGSINAPGILAGVFEFCRDTPVDQLSMPRLAAYLDVGVTSIYWYFKSKRELLDAM 72
Query 68 TDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLG 126
+ AL + + P + W + LR ++ A + + CDLI R +L+ +
Sbjct 73 AEEALVSFYESMPALRGDAWEDVLREFFKNFYALLAVDDLKCDLIARRIGSLTYQETITS 132
Query 127 AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDR 166
+ +A L AG A+ + +S + RG ++ +R
Sbjct 133 WPRAAELLAGLRDAGFPSSLAWHAFFTLSTYTRGFLLTER 172
>gi|111219898|ref|YP_710692.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111147430|emb|CAJ59080.1| Putative TetR-family transcriptional regulator [Frankia alni
ACN14a]
Length=283
Score = 93.6 bits (231), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 58/164 (36%), Positives = 85/164 (52%), Gaps = 10/164 (6%)
Query 8 RQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAM 67
R+RR RGS++ +I++ A +LA Q + LSMP L + LG GV S+Y YF KDDLL A+
Sbjct 23 RRRRARGSLSSGEIVAAARDLAAQDGLARLSMPALARRLGCGVMSVYRYFDTKDDLLAAL 82
Query 68 TDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLIL------IRAALSPK 121
D+ +S P G WR+ L + + R P +++L IRAAL+P
Sbjct 83 ADQVMSDLHRQLPPAGDGPWRDELITYFTAYRDLMESFPAYREVVLYAPTFVIRAALTPA 142
Query 122 TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLD 165
R ++ I L+ AGL L DA +Y+ + R V +
Sbjct 143 QLR----RLDTGIGLLLRAGLPLADAAAVYNVCFNYTRSFVAFE 182
>gi|271963480|ref|YP_003337676.1| TetR family transcriptional regulator [Streptosporangium roseum
DSM 43021]
gi|270506655|gb|ACZ84933.1| putative transcriptional regulator, TetR family [Streptosporangium
roseum DSM 43021]
Length=268
Score = 77.8 bits (190), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 65/226 (29%), Positives = 104/226 (47%), Gaps = 15/226 (6%)
Query 15 SINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSK 74
+++ + I+ A EL +D LSM LG LG G TSIYW+ KD+LL + D K
Sbjct 29 ALSRDQIVRAAMELLDTEGLDALSMRRLGARLGSGATSIYWHVANKDELLELVMDEVFGK 88
Query 75 YVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAI 134
P + WR+ + A +R ++P LI R +L P + ++ + +
Sbjct 89 VALPDPSVVG--WRDAVSMFAHGLRAALFEHPWSVALIGTRPSLGPNAMEISSR-LLRTF 145
Query 135 ANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPS------AIEHPVAID 188
+ G++L+ A SA+ +V G V ++ ++ AG+ S ++ V
Sbjct 146 SLAGFEGMALDYA---SSALMSYVLG-VTTPEIAWRAAMAGAELSDEGLMAGMKSAVDKA 201
Query 189 PATTPLLA--HATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSS 232
A P LA +A G G E NF++GL CILD + Q+S
Sbjct 202 AADHPELAARYAEYAGEDPGTSRELNFDFGLTCILDGLQERLRQAS 247
>gi|336119466|ref|YP_004574243.1| TetR family transcriptional regulator [Microlunatus phosphovorus
NM-1]
gi|334687255|dbj|BAK36840.1| TetR family transcriptional regulator [Microlunatus phosphovorus
NM-1]
Length=222
Score = 76.6 bits (187), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 72/230 (32%), Positives = 106/230 (47%), Gaps = 17/230 (7%)
Query 10 RRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTD 69
R R ++ E +++GA ELA +D L++ L LGV SIY Y K+ LL+A+ D
Sbjct 5 RAPRNTLTRERVLAGALELADSQGLDALTIRALATQLGVRPMSIYHYVATKEALLDALVD 64
Query 70 RALSKYVFATPYI--EAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGA 127
VF Y+ G+WRE L ARS+ + +P ++ RA P A L
Sbjct 65 -----VVFLELYVPTTTGEWREELTRRARSVHSSLGRHPWALTVMESRA--QPGPANLAG 117
Query 128 QEMEKAIANLV-TAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVA 186
E A+ +L+ TAG S+E A Y+ + + G + D + R S G SA E
Sbjct 118 HE---AVLDLLGTAGFSVEAAGHAYAVLDAFIYGFALQDAMLR---SVGLSTSAAEVRDG 171
Query 187 IDPATTPLLAHATGRGHRIGA-PDETNFEYGLECILDHAGRLIEQSSKAA 235
+D + P LA P +T+F+ GL L+ RL + AA
Sbjct 172 MDLSRHPRLAAMAAHYAEAQEYPLDTSFDIGLTIALEGIARLRDDGDGAA 221
>gi|254386339|ref|ZP_05001646.1| transcriptional regulator [Streptomyces sp. Mg1]
gi|194345191|gb|EDX26157.1| transcriptional regulator [Streptomyces sp. Mg1]
Length=251
Score = 76.3 bits (186), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 62/214 (29%), Positives = 104/214 (49%), Gaps = 20/214 (9%)
Query 13 RGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRAL 72
+G + + I +GA ELA + ++ L+M LG+HL V TS+Y + +++LL D L
Sbjct 40 QGGLTLDRITAGALELADREGLEALTMRRLGEHLQVRHTSLYRHVASREELLIETVDHML 99
Query 73 SKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEK 132
+ P ++ GDWR L AR R+ A +P + L+ L P R E
Sbjct 100 GEIRL--PSLD-GDWRAGLEAGAREFRRVLAAHPAVVPLLTAGQLLGPNALR----AREH 152
Query 133 AIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATT 192
A+A L+ G + A +Y V+ V G+ VLD + +++AG + E ++ P T
Sbjct 153 ALAELLAHGWAPRPAVHVYLTVTHFVIGAAVLDS-AGAARTAGQRAAMAELFASLSPRTH 211
Query 193 PLLAHATGRGHR----IGAPD-ETNFEYGLECIL 221
P++ HR + + D + F++GL +L
Sbjct 212 PVV-------HRHAELLNSLDPQAEFDFGLRTLL 238
>gi|294817429|ref|ZP_06776071.1| transcriptional regulator, TetR family protein [Streptomyces
clavuligerus ATCC 27064]
gi|326446237|ref|ZP_08220971.1| TetR family transcriptional repressor [Streptomyces clavuligerus
ATCC 27064]
gi|294322244|gb|EFG04379.1| transcriptional regulator, TetR family protein [Streptomyces
clavuligerus ATCC 27064]
Length=248
Score = 75.1 bits (183), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 71/226 (32%), Positives = 102/226 (46%), Gaps = 18/226 (7%)
Query 8 RQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAM 67
R RR++ +++ E I+S A L ID LSM LG LG G TS+Y + KD+L+ +
Sbjct 16 RTRREQPALSREQIVSEAVRLLDAEGIDALSMRKLGTRLGAGATSLYRHVANKDELIELV 75
Query 68 TDRALSKYVFATPYIEAGDWR--ETLRNHARSMRKTFADNPVLCDLI--LIRAALSPKTA 123
D + A A DWR TLR H +R F D+P + ++ + A L P
Sbjct 76 VDEVYGELDVADA-DRAPDWRAKATLRAHG--IRSMFLDHPWIVSVLGEMGVAYLGPNML 132
Query 124 RLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRG-----SVVLDRLSRKSQSAGSGP 178
RL ++ +A +AG L++A + V +V G + L L+R QS
Sbjct 133 RLS----DRMLAMFESAGFPLDEADNAVRMVFAYVTGMTTSEAAWLTMLARSGQSEQDWA 188
Query 179 SAIEHPVAIDPATTPLL--AHATGRGHRIGAPDETNFEYGLECILD 222
+ P L +AT R A E NF YGL+ ILD
Sbjct 189 RRLWPAAEQATRDHPRLQQTYATNRDKDPTALREQNFGYGLDRILD 234
>gi|345002701|ref|YP_004805555.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E]
gi|344318327|gb|AEN13015.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E]
Length=273
Score = 73.6 bits (179), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 72/250 (29%), Positives = 105/250 (42%), Gaps = 24/250 (9%)
Query 21 IISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP 80
I + A ++A I+ S+ + K LG G ++Y Y K+DL M D A P
Sbjct 31 IAAVAIDIADSEGIEAASVRAIAKRLGTGAMTLYRYLPAKEDLYTVMIDEATG----FEP 86
Query 81 YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTA 140
GD R L A R+ F +P L L+ R + P R ME+ +A L
Sbjct 87 QEPTGDLRADLTTLAHRRRQIFLRHPWLAPLLATRPIMGPNFMR----GMERDLAVLAGC 142
Query 141 GLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATG 200
GL +++ D+ + + V G+V + L+ ++ + SG + ++P LL ATG
Sbjct 143 GLGMDETVDVLNLIHSWVGGAVQAE-LTERANADRSGVDRHAWRLRMEPYLKSLL--ATG 199
Query 201 ---------RGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPT 251
+ IG DE FE GL ILD + + S A G RRP D
Sbjct 200 EFPHLSRMVQVSEIGEADE-RFENGLAIILDG---IEARFSTATGTNGARRPVGDTDGGP 255
Query 252 PGARAKAVAR 261
P R V R
Sbjct 256 PATRRATVQR 265
>gi|111223381|ref|YP_714175.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111150913|emb|CAJ62619.1| Putative TetR-family transcriptional regulator [Frankia alni
ACN14a]
Length=214
Score = 73.2 bits (178), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 41/129 (32%), Positives = 67/129 (52%), Gaps = 1/129 (0%)
Query 39 MPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSM 98
MP L L VGVTSIYWY++ K DLL+AMT+ AL+ + + P + AG W + LR
Sbjct 1 MPRLAAFLDVGVTSIYWYYKSKRDLLDAMTEEALAAFYESMPPLRAGGWEDMLRGFFDDC 60
Query 99 RKTFADNPVLCDLILIRAALSPKTARLGAQ-EMEKAIANLVTAGLSLEDAFDIYSAVSVH 157
A + + CDLI+ R + + + A + + L AG A+ + ++ +
Sbjct 61 YAALAADDLTCDLIVRRIGGATRQDAVAAWPRAAELLDGLREAGFPPSLAWHAFITLAAY 120
Query 158 VRGSVVLDR 166
RG ++ ++
Sbjct 121 TRGFLLTEQ 129
>gi|213969962|ref|ZP_03398095.1| transcriptional regulator, TetR family [Pseudomonas syringae
pv. tomato T1]
gi|213925287|gb|EEB58849.1| transcriptional regulator, TetR family [Pseudomonas syringae
pv. tomato T1]
Length=259
Score = 72.4 bits (176), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 59/226 (27%), Positives = 101/226 (45%), Gaps = 17/226 (7%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
K R R S++ E I++ A E +V +M +L + LG G ++Y +F KD++L
Sbjct 26 KSAGRGRPSVSVERIVATALEAVDEVGAQAFNMRMLAERLGSGTATLYRHFASKDEILIY 85
Query 67 MTDRALSKYVFATPYI----------EAGDWRETLRNHARSMRKTFADNPVLCDLILIRA 116
+ D L + + P E W++ + A + +P + L++ +
Sbjct 86 VVDSVLGELLADQPEAVELVPQGQGSEGYSWQKACASGAERLYGVLRRHPGILPLLVSQI 145
Query 117 ALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGS 176
+ P G + E+ IA + G E A Y++V+ +V G + + S S A
Sbjct 146 PIGPN----GLKRREQGIALFLANGFPAELAARAYTSVAHYVLG-FAIQQHSSASSEAAE 200
Query 177 GPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILD 222
G +E A+D + P +A A GR H G E F +GL+ I+D
Sbjct 201 GEELVEFFAALDASEYPAIATA-GR-HLPGVSVEEEFRFGLKLIID 244
>gi|294633314|ref|ZP_06711873.1| tetracycline repressor protein class D [Streptomyces sp. e14]
gi|292831095|gb|EFF89445.1| tetracycline repressor protein class D [Streptomyces sp. e14]
Length=243
Score = 72.0 bits (175), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 59/221 (27%), Positives = 106/221 (48%), Gaps = 18/221 (8%)
Query 5 PG-KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDL 63
PG +R R + + + ++ A +L + + L+M LG+ LGV ++Y Y KD L
Sbjct 28 PGARRGRGESVGLTRQRVLDAALDLVDRRGLKALTMRSLGEQLGVEAMTLYHYVPNKDAL 87
Query 64 LNAMTDRALSKYVFATPYIE-AGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKT 122
L+ + ++ + A P ++ + DWR+ LR +A+++R+ +P + L R A++ T
Sbjct 88 LDGLVEQV---FRAAAPAMDGSADWRDALRAYAKALREGLLRHPAVLPLAASRPAVTQAT 144
Query 123 ARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDR--LSRKSQSAGSGPSA 180
++E + L G +L A +AVSV G VL+ + +S G+G A
Sbjct 145 ----LDDIEACLRMLTENGFTLGRALHALNAVSVFAIGHAVLEAQLVVGAEESGGTGWLA 200
Query 181 IEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECIL 221
+D PL+A A R+G D F + ++ +L
Sbjct 201 -----GLDGERYPLIARAA--RDRVGVDDGERFAFAVDAML 234
>gi|331014441|gb|EGH94497.1| transcriptional regulator, TetR family protein [Pseudomonas syringae
pv. lachrymans str. M302278PT]
Length=242
Score = 72.0 bits (175), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 59/226 (27%), Positives = 101/226 (45%), Gaps = 17/226 (7%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
K R R S++ E I++ A E +V +M +L + LG G ++Y +F KD++L
Sbjct 9 KSAGRGRPSVSVERIVATALEAVDEVGAQAFNMRMLAERLGSGTATLYRHFASKDEILIY 68
Query 67 MTDRALSKYVFATPYI----------EAGDWRETLRNHARSMRKTFADNPVLCDLILIRA 116
+ D L + + P E W++ + A + +P + L++ +
Sbjct 69 VVDSVLGELLADQPEAVELVPQGQGSEGYSWQKACASGAERLYGVLRRHPGILPLLVSQI 128
Query 117 ALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGS 176
+ P G + E+ IA + G E A Y++V+ +V G + + S S A
Sbjct 129 PIGPN----GLKRREQGIALFLANGFPAELAARAYTSVAHYVLG-FAIQQHSSASSEAAE 183
Query 177 GPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILD 222
G +E A+D + P +A A GR H G E F +GL+ I+D
Sbjct 184 GEELVEFFAALDASEYPAIATA-GR-HLPGISVEEEFRFGLKLIID 227
>gi|28869835|ref|NP_792454.1| TetR family transcriptional regulator [Pseudomonas syringae pv.
tomato str. DC3000]
gi|28853080|gb|AAO56149.1| transcriptional regulator, TetR family [Pseudomonas syringae
pv. tomato str. DC3000]
Length=236
Score = 72.0 bits (175), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 59/226 (27%), Positives = 101/226 (45%), Gaps = 17/226 (7%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
K R R S++ E I++ A E +V +M +L + LG G ++Y +F KD++L
Sbjct 3 KSAGRGRPSVSVERIVATALEAVDEVGAQAFNMRMLAERLGSGTATLYRHFASKDEILIY 62
Query 67 MTDRALSKYVFATPYI----------EAGDWRETLRNHARSMRKTFADNPVLCDLILIRA 116
+ D L + + P E W++ + A + +P + L++ +
Sbjct 63 VVDSVLGELLADQPEAVELVPQGQGSEGYSWQKACASGAERLYGVLRRHPGILPLLVSQI 122
Query 117 ALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGS 176
+ P G + E+ IA + G E A Y++V+ +V G + + S S A
Sbjct 123 PIGPN----GLKRREQGIALFLANGFPAELAARAYTSVAHYVLG-FAIQQHSSASSEAAE 177
Query 177 GPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILD 222
G +E A+D + P +A A GR H G E F +GL+ I+D
Sbjct 178 GEELVEFFAALDASEYPAIATA-GR-HLPGISVEEEFRFGLKLIID 221
>gi|42509|emb|CAA24908.1| unnamed protein product [uncultured bacterium]
gi|2343036|gb|AAB67685.1| TetR [Cloning vector pJB3Tc20]
gi|2576386|gb|AAB82322.1| TetR [Expression vector pJB866]
Length=216
Score = 71.6 bits (174), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 65/210 (31%), Positives = 95/210 (46%), Gaps = 20/210 (9%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
+ P +I A +L +V +D L+ L + LGV ++YW+FR K LL+A+ + L++
Sbjct 4 LQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHFRNKRALLDALAEAMLAEN 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIA 135
+ DWR L +ARS R+ D I A P GA +ME A A
Sbjct 64 HSTSVPRADDDWRSFLTGNARSFRQALL---AYRDGARIHAGTRP-----GAPQMETADA 115
Query 136 N---LVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATT 192
L AG S DA + +S G+ VL+ + S+S G + + P+ +
Sbjct 116 QLRFLCEAGFSAGDAVNALMTISYFTVGA-VLEEQAGDSESGERGGTVEQAPL------S 168
Query 193 PLLAHATGRGHRIGAPDETNFEYGLECILD 222
PLL A G PD FE GL I+D
Sbjct 169 PLLRAAIDAFDEAG-PDAA-FEQGLAVIVD 196
>gi|66045614|ref|YP_235455.1| transcriptional repressor TetR [Pseudomonas syringae pv. syringae
B728a]
gi|63256321|gb|AAY37417.1| transcriptional regulator, TetR family [Pseudomonas syringae
pv. syringae B728a]
Length=260
Score = 71.6 bits (174), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 60/226 (27%), Positives = 103/226 (46%), Gaps = 17/226 (7%)
Query 7 KRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNA 66
K + R R S++ E II+ A E +V +M +L + L G ++Y +F KD++L
Sbjct 26 KSRSRGRPSVSAERIIATALEAVDEVGAQAFNMRMLAERLESGTATLYRHFASKDEILVY 85
Query 67 MTDRAL-------SKYVFATPYIEAGD---WRETLRNHARSMRKTFADNPVLCDLILIRA 116
+ D L S P + GD W++ + A + + +P + L++ +
Sbjct 86 VVDSVLGEMSADQSDAAEGAPQEQGGDEHAWQKACASGAERLYRVLRKHPGILPLLVSQI 145
Query 117 ALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGS 176
+ P G + E+ IA + G E A Y++V+ +V G + + S + A
Sbjct 146 PIGPN----GLKRREQGIALFLANGFPAELAARAYTSVAHYVLG-FAIQQHSNVASEATD 200
Query 177 GPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILD 222
G +E A+D + P +A A GR H G E F +GL+ I+D
Sbjct 201 GEDLVEFFSALDASEYPAIA-AAGR-HLPGVSVEDEFRFGLQLIID 244
>gi|111020021|ref|YP_702993.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
gi|110819551|gb|ABG94835.1| transcriptional regulator, TetR family protein [Rhodococcus jostii
RHA1]
Length=236
Score = 71.6 bits (174), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 52/159 (33%), Positives = 74/159 (47%), Gaps = 15/159 (9%)
Query 3 TTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDD 62
TTPG+ RR+R + E + AFELA++ L+M LG+ L V T++Y FR KD+
Sbjct 9 TTPGRTTRRERKGLQQEAAVKAAFELARRDGAAGLTMRRLGEELKVDATTLYRLFRDKDE 68
Query 63 LLNAMTDRALSKYVFATPYIEAGD------WRETLRNHARSMRKTFADNPVLCDLILIRA 116
LL A+ D A A E GD W++TLR A + T +P + L R
Sbjct 69 LLLAVYDHAT-----AVELEEIGDVPDSEHWQDTLRRIADRIWATAVRSPAIAALTFART 123
Query 117 ALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVS 155
P R+ +E + +GLS E Y A +
Sbjct 124 TGGPAERRM----VELILETFARSGLSREATVRYYRAFA 158
>gi|302752605|gb|ADL67001.1| synthetic iM2 transcription activator [synthetic construct]
Length=255
Score = 71.6 bits (174), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/210 (29%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR----AALSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ ++ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A R GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDRQGA--EPAFLFGLELII 194
>gi|331694208|ref|YP_004330447.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
gi|326948897|gb|AEA22594.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
Length=251
Score = 71.6 bits (174), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 68/234 (30%), Positives = 99/234 (43%), Gaps = 29/234 (12%)
Query 6 GKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN 65
G RQR + + ++SGA E+A Q +D LSM + +HLGVG S+Y Y K++L
Sbjct 30 GPRQR-----LTLDQVVSGAIEVASQQGVDELSMRKVAQHLGVGAMSLYTYVPGKEELFE 84
Query 66 AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARL 125
M DRA + + WR + HAR + NP L L R L P L
Sbjct 85 LMIDRAWAGRALPDRTLP---WRAQVEFHAREAWAMYQANPWLIRSNLWRMPLGPHV--L 139
Query 126 GAQE-MEKAIANLVTAGLSLEDAFDIYSAVSVHVRG---SVVLDRLSRKSQSAGSGPSAI 181
AQE + +A+ + GL + V HV G S V D S SA +G +
Sbjct 140 DAQEDLYRAV---LLTGLPATTVARVAGLVEAHVFGAARSAVTD----TSVSARTGVTQD 192
Query 182 EHP--------VAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRL 227
++ P P + H +G + +E+GL +LD R+
Sbjct 193 DYWESRQSFWGTYYTPERFPAMTHIWEQGGFDEEYSDAAWEFGLRLLLDGVERM 246
>gi|157835403|pdb|2NS7|A Chain A, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835404|pdb|2NS7|B Chain B, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835405|pdb|2NS7|C Chain C, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835406|pdb|2NS7|D Chain D, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835407|pdb|2NS8|A Chain A, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835408|pdb|2NS8|B Chain B, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835409|pdb|2NS8|C Chain C, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
gi|157835410|pdb|2NS8|D Chain D, How An In Vitro Selected Peptide Mimics The Antibiotic
Tetracycline To Induce Tet Repressor
Length=208
Score = 71.6 bits (174), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 57/206 (28%), Positives = 94/206 (46%), Gaps = 15/206 (7%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+ A EL +V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALAIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIA 135
+E W++ LRN+A+S R N +L + L + + +E +A
Sbjct 64 HTHFSPLEGESWQDFLRNNAKSFR-----NALLSHRDGAKVHLGTRPTEKQYETLENQLA 118
Query 136 NLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLL 195
L G SLE+A SAV GSV+ D+ + ++ P+ P PLL
Sbjct 119 FLTQQGFSLENALYALSAVGHFTLGSVLEDQEHQVAKEERETPTTDSMP--------PLL 170
Query 196 AHATGRGHRIGAPDETNFEYGLECIL 221
A GA E F +GLE ++
Sbjct 171 RQAIELFDHQGA--EPAFLHGLESLI 194
>gi|196968521|gb|ACG80832.1| rtTA-M2s* [Expression vector pDM310]
gi|196968528|gb|ACG80838.1| rtTA-M2s* [Expression vector pDM359]
gi|196968535|gb|ACG80844.1| rtTA-M2s* [Expression vector pDM360]
Length=292
Score = 71.2 bits (173), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/210 (29%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAA----LSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ ++ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A R GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDRQGA--EPAFLFGLELII 194
>gi|84795125|gb|ABC65842.1| rtTA-M2.alt [Expression vector peTetOn(PacI)]
gi|84795127|gb|ABC65843.1| rtTA-M2.alt [Expression vector pe2TetOn(PacI)]
gi|84795129|gb|ABC65844.1| rtTA-M2.alt [Expression vector pe2TetOn/FKNF(PacI)]
gi|84795131|gb|ABC65845.1| rtTA-M2.alt [Expression vector peTetOn/FKNF(PacI)]
Length=248
Score = 71.2 bits (173), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/210 (29%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR----AALSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ ++ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A R GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDRQGA--EPAFLFGLELII 194
>gi|330467812|ref|YP_004405555.1| TetR family transcriptional regulator [Verrucosispora maris AB-18-032]
gi|328810783|gb|AEB44955.1| TetR family transcriptional regulator [Verrucosispora maris AB-18-032]
Length=236
Score = 71.2 bits (173), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 71/238 (30%), Positives = 105/238 (45%), Gaps = 26/238 (10%)
Query 12 QRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRA 71
+R ++ E I+ A LA I +LSM L + LGV ++Y + KD+LL+AM D
Sbjct 9 RRTPLSRERILRTAIALADAAGIGSLSMRNLAQELGVVPMALYKHVANKDELLDAMIDMV 68
Query 72 LSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEME 131
+ + P E W++ +R S R +P I R +P A LG ++
Sbjct 69 VGEIDTPMPDTE---WKQAIRGRILSARSALQRHPWAALAIESRNMATP--AILG--YLD 121
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVL---DRLSRKSQSAG-SGPSAIEHPVAI 187
+A L + GLS + A + +H GS VL L ++ AG SGPS P A+
Sbjct 122 SVVATLRSGGLSADLAHHV-----MHAMGSRVLGFSQELFDTTRDAGRSGPSTAPQPAAM 176
Query 188 DPATTPLLAH----ATGRGHR------IGAPDETNFEYGLECILDHAGRLIEQSSKAA 235
P H AT H G D+ FE+ L+ +LD RL +Q +A
Sbjct 177 PPEVAARFPHLAEIATAASHDDASVVGSGCDDQFEFEFALDLLLDGIERLQQQGWTSA 234
>gi|330368227|gb|AEC11551.1| doxycycline-activated transcriptional activator [Xenopus transgenesis
plasmid pDPCrtTA-TREG-HS4]
Length=254
Score = 71.2 bits (173), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/210 (29%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR----AALSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ ++ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A R GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDRQGA--EPAFLFGLELII 194
>gi|183221843|ref|YP_001839839.1| TetR family transcriptional regulator [Leptospira biflexa serovar
Patoc strain 'Patoc 1 (Paris)']
gi|189911914|ref|YP_001963469.1| AcrR family transcriptional regulator [Leptospira biflexa serovar
Patoc strain 'Patoc 1 (Ames)']
gi|167776590|gb|ABZ94891.1| Transcriptional regulator, AcrR-family [Leptospira biflexa serovar
Patoc strain 'Patoc 1 (Ames)']
gi|167780265|gb|ABZ98563.1| Putative transcriptional regulator, TetR family [Leptospira biflexa
serovar Patoc strain 'Patoc 1 (Paris)']
Length=220
Score = 71.2 bits (173), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 54/203 (27%), Positives = 99/203 (49%), Gaps = 10/203 (4%)
Query 21 IISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP 80
++ A A + ID+LSM L + LGV S+Y + + KD+L++ M + + +F+ P
Sbjct 19 LVQTAISFADKNGIDSLSMRNLAQLLGVEAMSLYNHIQNKDELIDGMVESCV--ILFSLP 76
Query 81 YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTA 140
++ G W++ ++ ARS+R+ +P L L++ R + R +I LV A
Sbjct 77 KVK-GQWKKEMKRRARSVREVLLSHPWLTILLVSRVNIGESMLRY----FNDSIGCLVNA 131
Query 141 GLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATG 200
G + + A I +A+ H+ G L L+ + A E+ I P + +
Sbjct 132 GFTYKQADQIINAIDSHIYG-FTLQELNFPFKPNEYKSKASEYLPMI-PKNDLIYFYNLT 189
Query 201 RGHRIGAPD-ETNFEYGLECILD 222
+ +G + + NF++GL+ ILD
Sbjct 190 KEVAMGKYNGKQNFDFGLDLILD 212
>gi|157313363|gb|AAZ16157.2| adapted tetracycline-dependent transactivator [synthetic construct]
gi|307752607|gb|ADN93291.1| rTetR [synthetic construct]
Length=327
Score = 70.9 bits (172), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 59/205 (29%), Positives = 92/205 (45%), Gaps = 23/205 (11%)
Query 21 IISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATP 80
+I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 9 VINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRHHTHFC 68
Query 81 YIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAA----LSPKTARLGAQEMEKAIAN 136
+E W++ LRN+A+S R C L+ R L + + +E +A
Sbjct 69 PLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLENQLAF 119
Query 137 LVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLA 196
L G SLE+A SAV G V+ ++ + ++ P+ P PLL
Sbjct 120 LCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP--------PLLR 171
Query 197 HATGRGHRIGAPDETNFEYGLECIL 221
A R GA E F +GLE I+
Sbjct 172 QAIELFDRQGA--EPAFLFGLELII 194
>gi|313652102|gb|ADR71685.1| rtTA3 [Retroviral Tet-shRNA expression vector TRMPVIR]
gi|313652107|gb|ADR71689.1| rtTA3 [Retroviral Tet-shRNA expression vector TtRMPVIR]
Length=248
Score = 70.9 bits (172), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 59/210 (29%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+GA EL V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINGALELLNGVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALPIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR----AALSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSYR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ ++ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEEQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A R GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDRQGA--EPAFLFGLELII 194
>gi|196968542|gb|ACG80850.1| tTA [Expression vector pDM309]
Length=335
Score = 70.9 bits (172), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 58/210 (28%), Positives = 93/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+ A EL +V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 4 LDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALAIEMLDRH 63
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAA----LSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 64 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 114
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ D+ + ++ P+ P
Sbjct 115 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERETPTTDSMP------- 167
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A GA E F +GLE I+
Sbjct 168 -PLLRQAIELFDHQGA--EPAFLFGLELII 194
>gi|300823293|ref|ZP_07103425.1| tetracycline repressor protein class D [Escherichia coli MS 119-7]
gi|300524257|gb|EFK45326.1| tetracycline repressor protein class D [Escherichia coli MS 119-7]
Length=208
Score = 70.5 bits (171), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 58/210 (28%), Positives = 94/210 (45%), Gaps = 23/210 (10%)
Query 16 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKY 75
++ +I+ A EL +V I+ L+ L + LGV ++YW+ + K LL+A+ L ++
Sbjct 5 LDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRALLDALAIEMLDRH 64
Query 76 VFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR----AALSPKTARLGAQEME 131
+E W++ LRN+A+S R C L+ R L + + +E
Sbjct 65 HTHFCPLEGESWQDFLRNNAKSFR---------CALLSHRDGAKVHLGTRPTEKQYETLE 115
Query 132 KAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPAT 191
+A L G SLE+A SAV G V+ D+ + ++ P+ P
Sbjct 116 NQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERETPTTDSMP------- 168
Query 192 TPLLAHATGRGHRIGAPDETNFEYGLECIL 221
PLL A + GA E F +GLE I+
Sbjct 169 -PLLRQAIELFNHQGA--EPAFLFGLELII 195
Lambda K H
0.317 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 388543189928
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40