BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1354c Length=623 Score E Sequences producing significant alignments: (Bits) Value gi|15608494|ref|NP_215870.1| hypothetical protein Rv1354c [Mycob... 1253 0.0 gi|289446949|ref|ZP_06436693.1| GGDEF protein [Mycobacterium tub... 1251 0.0 gi|289753436|ref|ZP_06512814.1| GGDEF protein [Mycobacterium tub... 1249 0.0 gi|308231814|ref|ZP_07413870.2| hypothetical protein TMAG_03501 ... 1209 0.0 gi|120402963|ref|YP_952792.1| GAF sensor-containing diguanylate ... 800 0.0 gi|145224956|ref|YP_001135634.1| GAF sensor-containing diguanyla... 786 0.0 gi|315445287|ref|YP_004078166.1| diguanylate cyclase (GGDEF) dom... 784 0.0 gi|118467440|ref|YP_886551.1| sensory box/response regulator [My... 756 0.0 gi|15827936|ref|NP_302199.1| hypothetical protein ML1750 [Mycoba... 751 0.0 gi|108798716|ref|YP_638913.1| GAF sensor-containing diguanylate ... 750 0.0 gi|221230413|ref|YP_002503829.1| hypothetical protein MLBr_01750... 749 0.0 gi|240173013|ref|ZP_04751671.1| hypothetical protein MkanA1_2711... 715 0.0 gi|126437697|ref|YP_001073388.1| GAF sensor-containing diguanyla... 711 0.0 gi|108801710|ref|YP_641907.1| GAF sensor-containing diguanylate ... 707 0.0 gi|254821533|ref|ZP_05226534.1| cyclic diguanylate phosphodieste... 692 0.0 gi|296169849|ref|ZP_06851463.1| GGDEF protein [Mycobacterium par... 685 0.0 gi|342860614|ref|ZP_08717265.1| cyclic diguanylate phosphodieste... 681 0.0 gi|54026890|ref|YP_121132.1| hypothetical protein nfa49160 [Noca... 676 0.0 gi|118465484|ref|YP_882316.1| GGDEF domain-containing protein [M... 675 0.0 gi|254775582|ref|ZP_05217098.1| GGDEF domain-containing protein ... 672 0.0 gi|118462879|ref|YP_880384.1| cyclic diguanylate phosphodiestera... 669 0.0 gi|254820324|ref|ZP_05225325.1| GGDEF domain-containing protein ... 665 0.0 gi|41407047|ref|NP_959883.1| hypothetical protein MAP0949 [Mycob... 662 0.0 gi|342860779|ref|ZP_08717429.1| GGDEF domain-containing protein ... 660 0.0 gi|333990223|ref|YP_004522837.1| hypothetical protein JDM601_158... 659 0.0 gi|226365224|ref|YP_002783007.1| hypothetical protein ROP_58150 ... 638 0.0 gi|111022717|ref|YP_705689.1| hypothetical protein RHA1_ro05753 ... 623 2e-176 gi|258650469|ref|YP_003199625.1| GAF sensor-containing diguanyla... 579 6e-163 gi|258655343|ref|YP_003204499.1| GAF sensor-containing diguanyla... 561 2e-157 gi|294994911|ref|ZP_06800602.1| hypothetical protein Mtub2_10468... 433 4e-119 gi|294994912|ref|ZP_06800603.1| hypothetical protein Mtub2_10475... 431 1e-118 gi|336457797|gb|EGO36791.1| diguanylate cyclase (GGDEF) domain-c... 426 9e-117 gi|336461376|gb|EGO40247.1| diguanylate cyclase (GGDEF) domain-c... 423 4e-116 gi|41407444|ref|NP_960280.1| hypothetical protein MAP1346c [Myco... 352 2e-94 gi|74317474|ref|YP_315214.1| PAS/PAC sensor-containing diguanyla... 337 4e-90 gi|334341203|ref|YP_004546183.1| diguanylate cyclase [Desulfotom... 330 5e-88 gi|254503359|ref|ZP_05115510.1| hypothetical protein SADFL11_339... 323 5e-86 gi|158338665|ref|YP_001519842.1| PAS/PAC sensor-containing digua... 317 4e-84 gi|206601940|gb|EDZ38422.1| Diguanylate cyclase/phosphodiesteras... 316 1e-83 gi|124516000|gb|EAY57509.1| Diguanylate cyclase/phosphodiesteras... 313 4e-83 gi|134299209|ref|YP_001112705.1| PAS/PAC and GAF sensor-containi... 313 5e-83 gi|119486033|ref|ZP_01620095.1| Putative diguanylate cyclase/pho... 312 1e-82 gi|296132513|ref|YP_003639760.1| diguanylate cyclase/phosphodies... 312 1e-82 gi|337746728|ref|YP_004640890.1| PAS/PAC sensor-containing digua... 311 3e-82 gi|197118094|ref|YP_002138521.1| response receiver sensor diguan... 309 8e-82 gi|222053961|ref|YP_002536323.1| diguanylate cyclase/phosphodies... 308 1e-81 gi|34496829|ref|NP_901044.1| hypothetical protein CV_1374 [Chrom... 308 1e-81 gi|56477067|ref|YP_158656.1| putative sensory box/GGDEF family p... 307 4e-81 gi|218438075|ref|YP_002376404.1| PAS/PAC sensor-containing digua... 307 5e-81 gi|78222002|ref|YP_383749.1| diguanylate cyclase/phosphodiestera... 306 6e-81 >gi|15608494|ref|NP_215870.1| hypothetical protein Rv1354c [Mycobacterium tuberculosis H37Rv] gi|15840809|ref|NP_335846.1| hypothetical protein MT1397 [Mycobacterium tuberculosis CDC1551] gi|31792550|ref|NP_855043.1| hypothetical protein Mb1389c [Mycobacterium bovis AF2122/97] 55 more sequence titles Length=623 Score = 1253 bits (3241), Expect = 0.0, Method: Compositional matrix adjust. Identities = 623/623 (100%), Positives = 623/623 (100%), Gaps = 0/623 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA Sbjct 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR Sbjct 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL Sbjct 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI Sbjct 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL Sbjct 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH Sbjct 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL Sbjct 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL Sbjct 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ Sbjct 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA Sbjct 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 Query 601 MRHMLSARRLPPTCIPATDPALS 623 MRHMLSARRLPPTCIPATDPALS Sbjct 601 MRHMLSARRLPPTCIPATDPALS 623 >gi|289446949|ref|ZP_06436693.1| GGDEF protein [Mycobacterium tuberculosis CPHL_A] gi|289419907|gb|EFD17108.1| GGDEF protein [Mycobacterium tuberculosis CPHL_A] Length=623 Score = 1251 bits (3236), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/623 (99%), Positives = 622/623 (99%), Gaps = 0/623 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 MCND ATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA Sbjct 1 MCNDAATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR Sbjct 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL Sbjct 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI Sbjct 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL Sbjct 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH Sbjct 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL Sbjct 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL Sbjct 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ Sbjct 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA Sbjct 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 Query 601 MRHMLSARRLPPTCIPATDPALS 623 MRHMLSARRLPPTCIPATDPALS Sbjct 601 MRHMLSARRLPPTCIPATDPALS 623 >gi|289753436|ref|ZP_06512814.1| GGDEF protein [Mycobacterium tuberculosis EAS054] gi|289694023|gb|EFD61452.1| GGDEF protein [Mycobacterium tuberculosis EAS054] Length=623 Score = 1249 bits (3233), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/623 (99%), Positives = 622/623 (99%), Gaps = 0/623 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA Sbjct 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR Sbjct 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL Sbjct 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI Sbjct 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL Sbjct 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH Sbjct 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL Sbjct 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL Sbjct 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ Sbjct 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQG LFSRPVPGEA Sbjct 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGVLFSRPVPGEA 600 Query 601 MRHMLSARRLPPTCIPATDPALS 623 MRHMLSARRLPPTCIPATDPALS Sbjct 601 MRHMLSARRLPPTCIPATDPALS 623 >gi|308231814|ref|ZP_07413870.2| hypothetical protein TMAG_03501 [Mycobacterium tuberculosis SUMu001] gi|308369774|ref|ZP_07419019.2| hypothetical protein TMBG_01184 [Mycobacterium tuberculosis SUMu002] gi|308370696|ref|ZP_07422405.2| hypothetical protein TMCG_00989 [Mycobacterium tuberculosis SUMu003] 17 more sequence titles Length=602 Score = 1209 bits (3129), Expect = 0.0, Method: Compositional matrix adjust. Identities = 602/602 (100%), Positives = 602/602 (100%), Gaps = 0/602 (0%) Query 22 MTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLRL 81 MTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLRL Sbjct 1 MTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLRL 60 Query 82 IYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGL 141 IYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGL Sbjct 61 IYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGL 120 Query 142 LGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQH 201 LGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQH Sbjct 121 LGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQH 180 Query 202 LDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLG 261 LDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLG Sbjct 181 LDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLG 240 Query 262 GDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDL 321 GDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDL Sbjct 241 GDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDL 300 Query 322 LRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLR 381 LRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLR Sbjct 301 LRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLR 360 Query 382 TGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLG 441 TGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLG Sbjct 361 TGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLG 420 Query 442 HDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARL 501 HDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARL Sbjct 421 HDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARL 480 Query 502 KEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGF 561 KEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGF Sbjct 481 KEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGF 540 Query 562 QLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPA 621 QLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPA Sbjct 541 QLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPA 600 Query 622 LS 623 LS Sbjct 601 LS 602 >gi|120402963|ref|YP_952792.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium vanbaalenii PYR-1] gi|119955781|gb|ABM12786.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium vanbaalenii PYR-1] Length=617 Score = 800 bits (2066), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/611 (66%), Positives = 479/611 (79%), Gaps = 0/611 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 M + L+ ++T+VA +LM +AATS EVSQRVLA LV+ LGVDVSFLR+ND RA Sbjct 1 MSDSDTLRSLDLVITSVATKLMAANAATSVEVSQRVLAELVDYLGVDVSFLRYNDHKIRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 +RLVAEWP R +PDPDPL L+YFADADPVFA EH K+P+VFRPEPAT+DYQ+ IEE R Sbjct 61 SRLVAEWPVRPGVPDPDPLALVYFADADPVFAQSEHGKKPMVFRPEPATDDYQKRIEETR 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 VP TS AA PLVSGE+TTG+LGFIKFGDR+W ELN L IA+LFAQVQARV AE +L Sbjct 121 AVPATSMAAAPLVSGELTTGVLGFIKFGDREWTAEELNGLEAIASLFAQVQARVQAEEQL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RYLA+HDDLTGL+NRRALL HLD+RLA G+PGPV+ALF DLDRLKAINDYLGH AGD FI Sbjct 181 RYLAEHDDLTGLYNRRALLAHLDERLAEGRPGPVSALFFDLDRLKAINDYLGHTAGDWFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 V A+R+ ++IARLGGDEFVL+P PM AA+ LA RL+ L++ V+I GE+L Sbjct 241 RVLAERLRRGADCPNIIARLGGDEFVLVPTVPMDGAAAEALAHRLQSTLRERVSIDGEML 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 TRTVSIGVA G PG+ T SDLLRRADQA L AK +GG+ V +FT DMS+ E NDIELH Sbjct 301 TRTVSIGVAQGIPGRDTTSDLLRRADQAVLTAKGSGGNEVVVFTDDMSMRHEFNNDIELH 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 L+ IE+ AL L YLPEVD+RTG+I+ EALVRWQHPTRGLL+P FI VAESINLAGEL Sbjct 361 LQSVIENGALLLHYLPEVDMRTGEILACEALVRWQHPTRGLLSPESFIGVAESINLAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 RWV+R AC +F+ W++ G+G ++RINVS QLVT GFV+ VA + + LD SVCL Sbjct 421 GRWVMRSACADFAGWRARGIGTGTVMRINVSPVQLVTDGFVESVAGIVDEFDLDEGSVCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITE+VVVQD+ T R TL LKE GV IAIDDFGTGYSA+S L++LP+DTLKIDK+FVR+ Sbjct 481 EITESVVVQDIETTRVTLKGLKEAGVRIAIDDFGTGYSALSHLKSLPVDTLKIDKSFVRE 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 LG++ DL IVR ++ LAE F L++VAEGVETEAAA LL C+RAQGFL SRP+ G A Sbjct 541 LGSDPGDLAIVRAVIALAEAFGLELVAEGVETEAAAMTLLRHGCHRAQGFLLSRPIDGAA 600 Query 601 MRHMLSARRLP 611 M+ +L+ R+P Sbjct 601 MKALLARGRVP 611 >gi|145224956|ref|YP_001135634.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium gilvum PYR-GCK] gi|145217442|gb|ABP46846.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium gilvum PYR-GCK] Length=612 Score = 786 bits (2031), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/605 (65%), Positives = 475/605 (79%), Gaps = 0/605 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 + L+ +VT+VA +LM AAT AE SQ+VLA LVE GVDVSFLR ND RA+ LVAE Sbjct 2 SESLDLVVTSVATRLMGAGAATWAEASQQVLADLVEHFGVDVSFLRRNDHTIRASVLVAE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WP R IPDPDPL ++YFADADPVFAL E KEPLVFRP+ T++YQ+ IEE R VP S Sbjct 62 WPVRPGIPDPDPLAVVYFADADPVFALAEFQKEPLVFRPDANTDEYQKTIEEGRQVPQVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 AAVPL+SG++TTG+LGF+KFGDR W ELNAL IA+LFAQVQARV AE +LRYLA+H Sbjct 122 MAAVPLLSGDVTTGVLGFVKFGDRDWTGVELNALKAIASLFAQVQARVEAETQLRYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDLTGL+NRRALL HLD RLA GQPGPV+ALF DLDRLKAINDYLGH AGD FI V A+R Sbjct 182 DDLTGLNNRRALLSHLDGRLAEGQPGPVSALFFDLDRLKAINDYLGHTAGDWFIRVLAER 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + + +LIARLGGDEFV++PA PM +AA+ LA +L+ LK+ V+I GE+LTRTVSI Sbjct 242 LREGADPRALIARLGGDEFVVVPAGPMDGEAAESLAHQLQSTLKERVSIDGEMLTRTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA G PGQ T SDLLRRADQA L AK++GG+ V +FT +MS+ E NDIELHL+ IE Sbjct 302 GVAVGIPGQDTTSDLLRRADQAVLTAKNSGGNRVTVFTEEMSLKQEFNNDIELHLQSVIE 361 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 + AL L YLPE+D+RTGDI+ EALVRWQHPTRGLL+P FI VAESINLAGEL RWV+R Sbjct 362 NGALLLHYLPEIDMRTGDILAMEALVRWQHPTRGLLSPESFIGVAESINLAGELGRWVMR 421 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC +F+ W++ G+G DA++RINVS QLVT GFV+ VA + + GL+ SVCLEITE+V Sbjct 422 SACTDFARWRALGIGKDAIMRINVSPVQLVTDGFVESVAGIVDEFGLEHGSVCLEITESV 481 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQD+ T R TL LK+ GV +AIDDFGTGYSA+S L++LP+DTLKIDK+FVR+LG++ Sbjct 482 VVQDIETTRVTLNGLKKAGVLVAIDDFGTGYSALSHLKSLPVDTLKIDKSFVRELGSDPG 541 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR I+ LAE F L++VAEGVET+ A LL C+RAQGFL SRP+P +AM +L+ Sbjct 542 DLAIVRAIIALAEAFGLELVAEGVETDVGALTLLRHGCHRAQGFLLSRPIPTDAMETLLA 601 Query 607 ARRLP 611 R+P Sbjct 602 QGRIP 606 >gi|315445287|ref|YP_004078166.1| diguanylate cyclase (GGDEF) domain-containing protein [Mycobacterium sp. Spyr1] gi|315263590|gb|ADU00332.1| diguanylate cyclase (GGDEF) domain-containing protein [Mycobacterium sp. Spyr1] Length=612 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/605 (65%), Positives = 474/605 (79%), Gaps = 0/605 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 + L+ +VT+VA +LM AAT AE SQ+VLA LVE GVDVSFLR ND RA+ LVAE Sbjct 2 SESLDLVVTSVATRLMGAGAATWAEASQQVLADLVEHFGVDVSFLRRNDHTIRASVLVAE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WP R IPDPDPL ++YFADADPVFAL E KEPLVFRP+ T++YQ+ IEE R VP S Sbjct 62 WPVRPGIPDPDPLAVVYFADADPVFALAEFQKEPLVFRPDANTDEYQKTIEEGRQVPQVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 AAVPL+SG++TTG+LGF+KFGDR W ELNAL IA+LFAQVQARV AE +LRYLA+H Sbjct 122 MAAVPLLSGDVTTGVLGFVKFGDRDWTGVELNALKAIASLFAQVQARVEAETQLRYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDLTGL+NRRALL HLD RLA GQPGPV+ALF DLDRLKAINDYLGH AGD FI V A+R Sbjct 182 DDLTGLNNRRALLSHLDGRLAEGQPGPVSALFFDLDRLKAINDYLGHTAGDWFIRVLAER 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + + +LIARLGGDEFV++PA PM +AA+ LA L+ LK+ V+I GE+LTRTVSI Sbjct 242 LREGADPRALIARLGGDEFVVVPAGPMDGEAAELLAHHLQSTLKERVSIDGEMLTRTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA G PGQ T SDLLRRADQA L AK++GG+ V +FT +MS+ E NDIELHL+ IE Sbjct 302 GVAVGIPGQDTTSDLLRRADQAVLTAKNSGGNRVTVFTEEMSLKQEFNNDIELHLQSVIE 361 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 + AL L YLPE+D+RTGDI+ EALVRWQHPTRGLL+P FI VAESINLAGEL RWV+R Sbjct 362 NGALLLHYLPEIDMRTGDILAMEALVRWQHPTRGLLSPESFIGVAESINLAGELGRWVMR 421 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC +F+ W++ G+G DA++RINVS QLVT GFV+ VA + + GL+ SVCLEITE+V Sbjct 422 SACTDFARWRALGIGKDAIMRINVSPVQLVTDGFVESVAGIVDEFGLEHGSVCLEITESV 481 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQD+ T R TL LK+ GV +AIDDFGTGYSA+S L++LP+DTLKIDK+FVR+LG++ Sbjct 482 VVQDIETTRVTLNGLKKAGVLVAIDDFGTGYSALSHLKSLPVDTLKIDKSFVRELGSDPG 541 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR I+ LAE F L++VAEGVET+ A LL C+RAQGFL SRP+P +AM +L+ Sbjct 542 DLAIVRAIIALAEAFGLELVAEGVETDVGALTLLRHGCHRAQGFLLSRPIPTDAMETLLA 601 Query 607 ARRLP 611 R+P Sbjct 602 QGRIP 606 >gi|118467440|ref|YP_886551.1| sensory box/response regulator [Mycobacterium smegmatis str. MC2 155] gi|118168727|gb|ABK69623.1| sensory box/response regulator [Mycobacterium smegmatis str. MC2 155] Length=615 Score = 756 bits (1953), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/605 (63%), Positives = 459/605 (76%), Gaps = 0/605 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 + L+ LVT+VA QLM V+AATS VSQ+VLA LV VDVSFLRHND ATRLVAE Sbjct 2 SESLDVLVTSVATQLMAVEAATSVSVSQQVLAELVSFFDVDVSFLRHNDHRAHATRLVAE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WPPR DP+ +++FADADPVFA+ EH KEP VFRPEP +DYQR IE R +P TS Sbjct 62 WPPRPVDAATDPIAVVHFADADPVFAMAEHLKEPAVFRPEPLYDDYQRTIEAGRHIPATS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 A VPL+SG++TTG+LGF+KFGDR+W AELNAL IA+LFAQVQAR+ AE RLRYLADH Sbjct 122 MACVPLLSGDVTTGVLGFVKFGDREWLPAELNALKAIASLFAQVQARIEAEERLRYLADH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 D LTGL+NRRAL+ HL+ RLAPGQPGPVA +F DLDRLKAINDYLGH AGD FI + AQR Sbjct 182 DHLTGLYNRRALMAHLEARLAPGQPGPVAVMFFDLDRLKAINDYLGHTAGDAFISILAQR 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + LIARLGGDEFV++P PMS D A LA RL+ L++ V + GE+LTRTVSI Sbjct 242 LQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAYRLQSVLRERVTVDGEMLTRTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 G+A G PG+ + SD+L RAD A L AK +GG+ VA+F+ M++ + RNDIELHL+ IE Sbjct 302 GIAQGIPGKDSTSDVLNRADHAVLTAKGSGGNRVAVFSDAMAMEIDFRNDIELHLQSVIE 361 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 AL L YLPE+D+RTG+++ EALVRW+HPTRGLL+P FI VAESINLAGEL RWVLR Sbjct 362 GGALVLHYLPEIDMRTGEVLAAEALVRWEHPTRGLLSPDSFIGVAESINLAGELGRWVLR 421 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC EFS W++ G+G + +LRINVS QLVT GFV+ VA + + GL SVCLEITE+V Sbjct 422 TACAEFSRWRANGVGRNIVLRINVSPVQLVTDGFVESVAGIMKEFGLPRGSVCLEITESV 481 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQD+ T R TL L VGV +AIDDFGTGYS +SLL++LP+DTLKID++FV +LG+N Sbjct 482 VVQDIETTRTTLTGLHNVGVQVAIDDFGTGYSVLSLLKSLPVDTLKIDRSFVAELGSNPG 541 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR ++ LA F L +VAEGVETE AA LL CYRAQGFL S+P+ G M+ +L+ Sbjct 542 DLPIVRAVIALAGAFGLQLVAEGVETERAALTLLRHGCYRAQGFLLSKPILGSEMQTLLA 601 Query 607 ARRLP 611 R+P Sbjct 602 KGRVP 606 >gi|15827936|ref|NP_302199.1| hypothetical protein ML1750 [Mycobacterium leprae TN] gi|13093489|emb|CAC30703.1| conserved hypothetical protein [Mycobacterium leprae] Length=623 Score = 751 bits (1939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/605 (64%), Positives = 464/605 (77%), Gaps = 2/605 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 T L+ELVT VA++LM AAT+ +S+ VLA LVE GVDVSFLRHN+ D AT+L+ E Sbjct 2 TRSLDELVTRVASKLMAATAATAVTISEGVLAILVEHFGVDVSFLRHNNHDIHATKLIVE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WPPR +PDPDP+ ++YFADADPVFA+ E+ KEP V RPEPA DYQR IEE VP S Sbjct 62 WPPRDYVPDPDPIGVVYFADADPVFAMAEYLKEPAVLRPEPANADYQRRIEEGASVPAVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 A VPL+SGEITTG+LGF+K+GDR+WH+ EL AL IATLFAQ+QAR+ AE +LRYLA+H Sbjct 122 LACVPLLSGEITTGVLGFVKYGDREWHDDELRALQAIATLFAQLQARIVAEEQLRYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDLTGL NRRAL+ HLD+RLA GQ GPV LFL LDRLKA+NDYLGH AGD+ I VFA R Sbjct 182 DDLTGLLNRRALIAHLDERLADGQRGPVTLLFLGLDRLKAVNDYLGHNAGDRLIEVFADR 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + +A ++IAR GGDEFV++PA +S D A+ A RL+ +L+ V I GE+LTRTVSI Sbjct 242 LREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAHRLQTRLQKQVVIDGEILTRTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA+G PG+ T SDLLR AD AAL+AK + G V + +S LR ++ELHL I+ Sbjct 302 GVATGLPGRDTTSDLLRWADHAALSAK-SDGSKVVVLDHGISAQHTLRTEVELHLAGMID 360 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 +D L L YLPEVD+ TG ++GTEALVRWQHPTRGLL P FIPVAESINLAG+L R V+ Sbjct 361 TD-LVLHYLPEVDMSTGKVLGTEALVRWQHPTRGLLFPDSFIPVAESINLAGKLGRMVMH 419 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC EFS W+SAG+G DALLRINVS QLV GFVD VA T+ + GLD S VCLEITENV Sbjct 420 SACAEFSRWRSAGVGLDALLRINVSPVQLVAEGFVDNVAGTLDEFGLDGSMVCLEITENV 479 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQ++ R TLA LKEVGVH+AIDDFGTGYS ++ L++LP+DT+KIDK+FV +LG+N S Sbjct 480 VVQNIDATRKTLAGLKEVGVHLAIDDFGTGYSVLTHLKSLPVDTIKIDKSFVAELGSNAS 539 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR IM LA+ F+L+VVAEGVET AA++LL+ C RAQGFL SRPV G AM +L+ Sbjct 540 DLAIVRAIMALAKEFELEVVAEGVETAVAAQVLLELGCNRAQGFLLSRPVDGAAMESLLA 599 Query 607 ARRLP 611 +P Sbjct 600 KGVIP 604 >gi|108798716|ref|YP_638913.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium sp. MCS] gi|119867834|ref|YP_937786.1| diguanylate cyclase/phosphodiesterase [Mycobacterium sp. KMS] gi|126434319|ref|YP_001070010.1| diguanylate cyclase/phosphodiesterase [Mycobacterium sp. JLS] gi|108769135|gb|ABG07857.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium sp. MCS] gi|119693923|gb|ABL90996.1| diguanylate cyclase/phosphodiesterase [Mycobacterium sp. KMS] gi|126234119|gb|ABN97519.1| diguanylate cyclase/phosphodiesterase [Mycobacterium sp. JLS] Length=601 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/605 (64%), Positives = 461/605 (77%), Gaps = 13/605 (2%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 LE LVT VA LM V AATSA+VS+RVL LV L VD SFLRH+D A+ LVAEWP Sbjct 4 NLEVLVTAVAIDLMAVTAATSAQVSERVLGDLVSYLDVDASFLRHHDHRVHASELVAEWP 63 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 PR + PDPL+++YF+DADPVFA EH EP + RP PA R + A Sbjct 64 PRTSPGGPDPLKVVYFSDADPVFAQTEHLGEPAILRPAPADATGPR--------GAATVA 115 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 +PL SG++TTG+LGF+KFGDR W + ELNAL IA+LFAQVQAR+AAE RLRYLADHDD Sbjct 116 EIPLRSGDVTTGVLGFVKFGDRVWEQDELNALTAIASLFAQVQARIAAEERLRYLADHDD 175 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRI- 247 LTGLHNRRALL+HLD RLA G+PGPVA LF DLDRLKA+NDYLGH AGD FI V A+R+ Sbjct 176 LTGLHNRRALLRHLDDRLAAGRPGPVAVLFFDLDRLKAVNDYLGHIAGDWFIRVLAERLQ 235 Query 248 -GDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 GD + IARLGGDEFV++PA+P +AD A+ LA RL+ L++ V+I GE+LTRT+SI Sbjct 236 QGDE---KKFIARLGGDEFVVVPAAPTTADDAETLAHRLQAVLRERVSIDGELLTRTISI 292 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA GTPG+ T SDLL RADQA L+AK GG+S+++F+ MS LRNDIELHL+ I+ Sbjct 293 GVAVGTPGRDTTSDLLSRADQAVLSAKGEGGNSISVFSEQMSQEITLRNDIELHLQSVID 352 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 S AL L YLPEVD+RTG+I+ TEALVRWQHPTRGLL+P FI VAESINLAGEL RWVLR Sbjct 353 SGALVLHYLPEVDIRTGEILATEALVRWQHPTRGLLSPDRFIGVAESINLAGELGRWVLR 412 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC EF+ W++AG+G +LR+NVS QLVT GFV+ VAD + GL+ SVCLEITE+V Sbjct 413 NACAEFARWRAAGVGDRIVLRVNVSPVQLVTEGFVESVADVMADFGLERGSVCLEITESV 472 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQD+ T R TLA LKE GV +AIDDFGTGYS +SLL++LP+DTLKIDK+FVR LG N Sbjct 473 VVQDIDTTRVTLAGLKEAGVKVAIDDFGTGYSVLSLLKSLPVDTLKIDKSFVRDLGVNAG 532 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR I+ LA F L++VAEGVETE AA+ LLD C+RAQGFL SRPVPGE M +L+ Sbjct 533 DLAIVRAIIALAAAFGLELVAEGVETEIAAQTLLDHGCHRAQGFLLSRPVPGEQMERLLA 592 Query 607 ARRLP 611 R+P Sbjct 593 EGRIP 597 >gi|221230413|ref|YP_002503829.1| hypothetical protein MLBr_01750 [Mycobacterium leprae Br4923] gi|219933520|emb|CAR71845.1| conserved hypothetical protein [Mycobacterium leprae Br4923] Length=623 Score = 749 bits (1934), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/605 (64%), Positives = 463/605 (77%), Gaps = 2/605 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 T L+ELVT VA++LM AAT+ +S+ VLA LVE GVDVSFLRHN+ D T+L+ E Sbjct 2 TRSLDELVTRVASKLMAATAATAVTISEGVLAILVEHFGVDVSFLRHNNHDIHETKLIVE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WPPR +PDPDP+ ++YFADADPVFA+ E+ KEP V RPEPA DYQR IEE VP S Sbjct 62 WPPRDYVPDPDPIGVVYFADADPVFAMAEYLKEPAVLRPEPANADYQRRIEEGASVPAVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 A VPL+SGEITTG+LGF+K+GDR+WH+ EL AL IATLFAQ+QAR+ AE +LRYLA+H Sbjct 122 LACVPLLSGEITTGVLGFVKYGDREWHDDELRALQAIATLFAQLQARIVAEEQLRYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDLTGL NRRAL+ HLD+RLA GQ GPV LFL LDRLKA+NDYLGH AGD+ I VFA R Sbjct 182 DDLTGLLNRRALIAHLDERLADGQRGPVTLLFLGLDRLKAVNDYLGHNAGDRLIEVFADR 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + +A ++IAR GGDEFV++PA +S D A+ A RL+ +L+ V I GE+LTRTVSI Sbjct 242 LREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAHRLQTRLQKQVVIDGEILTRTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA+G PG+ T SDLLR AD AAL+AK + G V + +S LR ++ELHL I+ Sbjct 302 GVATGLPGRDTTSDLLRWADHAALSAK-SDGSKVVVLDHGISAQHTLRTEVELHLAGMID 360 Query 367 SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 +D L L YLPEVD+ TG ++GTEALVRWQHPTRGLL P FIPVAESINLAG+L R V+ Sbjct 361 TD-LVLHYLPEVDMSTGKVLGTEALVRWQHPTRGLLFPDSFIPVAESINLAGKLGRMVMH 419 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC EFS W+SAG+G DALLRINVS QLV GFVD VA T+ + GLD S VCLEITENV Sbjct 420 SACAEFSRWRSAGVGLDALLRINVSPVQLVAEGFVDNVAGTLDEFGLDGSMVCLEITENV 479 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQ++ R TLA LKEVGVH+AIDDFGTGYS ++ L++LP+DT+KIDK+FV +LG+N S Sbjct 480 VVQNIDATRKTLAGLKEVGVHLAIDDFGTGYSVLTHLKSLPVDTIKIDKSFVAELGSNAS 539 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR IM LA+ F+L+VVAEGVET AA++LL+ C RAQGFL SRPV G AM +L+ Sbjct 540 DLAIVRAIMALAKEFELEVVAEGVETAVAAQVLLELGCNRAQGFLLSRPVDGAAMESLLA 599 Query 607 ARRLP 611 +P Sbjct 600 KGVIP 604 >gi|240173013|ref|ZP_04751671.1| hypothetical protein MkanA1_27111 [Mycobacterium kansasii ATCC 12478] Length=617 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/602 (61%), Positives = 443/602 (74%), Gaps = 0/602 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 ++ +VT+VA QLM A+T+ +VSQRVLA LVEQ VD SFLRH+D + RA+ LVAEWPP Sbjct 1 MDLVVTSVATQLMEATASTATQVSQRVLAQLVEQFDVDASFLRHHDHEIRASVLVAEWPP 60 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R ++ DPDP +++F ADPV CEH ++P+V RP ++R + + S AA Sbjct 61 RRDVADPDPEGVVHFTSADPVLTQCEHGRKPVVIRPHRNNRFFRRWLGGSIAAASPSVAA 120 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 PLVSG+ TTG+LGF+KFG RKW E+N L +A LFAQ+QAR+AAE +LRYLA+HDDL Sbjct 121 APLVSGQATTGVLGFVKFGARKWRHEEINTLEAVAALFAQLQARIAAEEKLRYLAEHDDL 180 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGLHNRRALL HL +RLA G PGPVA L+LDLDRLK+INDYLGH AGD FI +FAQR+ Sbjct 181 TGLHNRRALLAHLSERLAAGTPGPVAVLYLDLDRLKSINDYLGHNAGDWFIRLFAQRLRG 240 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 + G+S+IARLGGDEFV+IP MS AA+ A RL L++ +AIGG +TRTVSIG+A Sbjct 241 CVGGQSMIARLGGDEFVVIPDQAMSKGAAESFARRLSSMLRERLAIGGHQITRTVSIGLA 300 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDA 369 G PG+ +DLLRRAD+A L AK AGG+ VA+ T DMS+ RNDIELHL+ I+SDA Sbjct 301 VGMPGRDDGTDLLRRADEAVLTAKRAGGNQVALATDDMSLKSAFRNDIELHLQGDIDSDA 360 Query 370 LRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRAC 429 L L YLPEVDL TG +V EALVRW+HP GLL P FI VAES NLAGEL R V+R AC Sbjct 361 LVLHYLPEVDLWTGAVVAAEALVRWRHPIWGLLLPDSFIGVAESTNLAGELGRCVMRSAC 420 Query 430 NEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQ 489 EFS W+ G+G A+LRINVS QL+T GFV VADTI + G+D SVCLEITE VV Sbjct 421 AEFSRWRKNGVGQSAVLRINVSPVQLITRGFVRSVADTIEEFGIDGGSVCLEITERAVVH 480 Query 490 DLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLV 549 D+ R TL+ LK+VGV +AIDDFGTGY+ +S L++LP+D LKID FVR LGTN DL Sbjct 481 DIEATRKTLSELKDVGVQVAIDDFGTGYAVLSHLKSLPVDMLKIDTGFVRDLGTNAGDLA 540 Query 550 IVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARR 609 IVR I+ LAE F L VVAEGVET AAA L+ C+RAQGFL SRPVPG AM +LSAR Sbjct 541 IVRAIIGLAEAFGLQVVAEGVETPAAALTLMQHGCHRAQGFLLSRPVPGNAMEALLSARW 600 Query 610 LP 611 +P Sbjct 601 MP 602 >gi|126437697|ref|YP_001073388.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium sp. JLS] gi|126237497|gb|ABO00898.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium sp. JLS] Length=623 Score = 711 bits (1835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/606 (61%), Positives = 451/606 (75%), Gaps = 2/606 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 T L+++VT A +LM A E RVLA +V LGVD SFLRHND +AT+LVAE Sbjct 2 TRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVAE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WP R +IPDPDP+ IYFA+ADPVF E+ K PL+ RPEP +DYQR IEE RGVP S Sbjct 62 WPIRDHIPDPDPIGTIYFAEADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 A VPL+SGE+T+G+LGFIK GDR+W E NAL IATLFAQ+QAR+AAE +L+YLA+H Sbjct 122 MACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIATLFAQLQARIAAEEQLQYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDL+GL NRRAL+ HLD+RLA GQPGPV+ LFLDLDRLK +NDYLGH+AGDQFI +FA+R Sbjct 182 DDLSGLLNRRALMAHLDRRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAER 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + ++IAR+GGDEFV++P PM A + A RL+ L+ V I GE+L RTVSI Sbjct 242 LRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA GTPG T SDLLRRADQAAL+AK GG A+FT +M+ +RNDIELHL I+ Sbjct 302 GVAVGTPGDDTTSDLLRRADQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVID 361 Query 367 --SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWV 424 S AL L YLPE+D+RTG ++GTEALVRW+HPTRGLL P FI VAESINLAG+L R V Sbjct 362 EASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLLPESFIGVAESINLAGKLGRLV 421 Query 425 LRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITE 484 +R AC +F+ W+S DA+LR+NVS QLV+ GF VA T+ + G+D S+VCLEITE Sbjct 422 MRSACADFARWRSRRTAGDAILRLNVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEITE 481 Query 485 NVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTN 544 +VVVQD+ R TLA LKEVGV IAIDDFGTGYS ++ L++LP+DT+KID++FVR LG + Sbjct 482 SVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGAS 541 Query 545 TSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHM 604 DL IVR I+ LA+ F+L+VVAEGVET AAA+ LL+ C RAQGF+ SRPV AM + Sbjct 542 PGDLAIVRAILALADAFELEVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEAL 601 Query 605 LSARRL 610 R+ Sbjct 602 FREGRI 607 >gi|108801710|ref|YP_641907.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium sp. MCS] gi|119870861|ref|YP_940813.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Mycobacterium sp. KMS] gi|108772129|gb|ABG10851.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium sp. MCS] gi|119696950|gb|ABL94023.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Mycobacterium sp. KMS] Length=623 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/606 (61%), Positives = 448/606 (74%), Gaps = 2/606 (0%) Query 7 TPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAE 66 T L+++VT A +LM A E RVLA +V LGVD SFLRHND +AT+LVAE Sbjct 2 TRTLDQVVTAAAAELMAATATNVVESCTRVLADVVAHLGVDFSFLRHNDHTIKATKLVAE 61 Query 67 WPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTS 126 WP R IPDPDP+ IYFA+ADPVF E+ K PL+ RPEP +DYQR IEE RGVP S Sbjct 62 WPIRDYIPDPDPIGTIYFAEADPVFRQAEYLKTPLIVRPEPDNDDYQRRIEEGRGVPSVS 121 Query 127 AAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADH 186 A VPL+SGE+T+G+LGFIK GDR+W E NAL IATLFAQ+QAR+AAE +L+YLA+H Sbjct 122 MACVPLLSGEMTSGILGFIKIGDREWTTEEQNALQAIATLFAQLQARIAAEEQLQYLAEH 181 Query 187 DDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQR 246 DDL+GL NRRAL+ HL RLA GQPGPV+ LFLDLDRLK +NDYLGH+AGDQFI +FA+R Sbjct 182 DDLSGLLNRRALMAHLGLRLAEGQPGPVSVLFLDLDRLKTVNDYLGHSAGDQFIKMFAER 241 Query 247 IGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSI 306 + ++IAR+GGDEFV++P PM A + A RL+ L+ V I GE+L RTVSI Sbjct 242 LRAGTEKPAVIARVGGDEFVVVPDEPMDVVAVESFARRLQTWLQRRVVIDGEMLARTVSI 301 Query 307 GVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE 366 GVA GTPG T SDLLRRADQAAL+AK GG A+FT +M+ +RNDIELHL I+ Sbjct 302 GVAVGTPGDDTTSDLLRRADQAALSAKSTGGSKTAVFTTEMASQHAIRNDIELHLEGVID 361 Query 367 --SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWV 424 S AL L YLPE+D+RTG ++GTEALVRW+HPTRGLL P FI VAESINLAG+L R V Sbjct 362 EASSALVLHYLPEIDMRTGKVLGTEALVRWRHPTRGLLLPESFIGVAESINLAGKLGRLV 421 Query 425 LRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITE 484 +R AC +F+ W+S DA+LRINVS QLV+ GF VA T+ + G+D S+VCLEITE Sbjct 422 MRSACADFARWRSRRTAGDAILRINVSPVQLVSDGFAATVAGTLDEFGVDGSAVCLEITE 481 Query 485 NVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTN 544 +VVVQD+ R TLA LKEVGV IAIDDFGTGYS ++ L++LP+DT+KID++FVR LG + Sbjct 482 SVVVQDIEATRHTLAALKEVGVRIAIDDFGTGYSVLTHLKSLPVDTVKIDRSFVRDLGAS 541 Query 545 TSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHM 604 DL IVR I+ LA+ F+L+VVAEGVET AAA+ LL+ C RAQGF+ SRPV AM + Sbjct 542 PGDLAIVRAILALADAFELEVVAEGVETVAAAKTLLELGCPRAQGFMLSRPVDAAAMEAL 601 Query 605 LSARRL 610 R+ Sbjct 602 FREGRI 607 >gi|254821533|ref|ZP_05226534.1| cyclic diguanylate phosphodiesterase domain-containing protein [Mycobacterium intracellulare ATCC 13950] Length=621 Score = 692 bits (1785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/603 (59%), Positives = 435/603 (73%), Gaps = 0/603 (0%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 L +VT+VA LM A T+ VS++VLA LVEQ VD SFLRH+D D A+ LVAEWP Sbjct 4 SLNLVVTSVATALMEATAPTATSVSEKVLARLVEQFDVDASFLRHHDNDAAASTLVAEWP 63 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 R + DPD + + + V A CE ++P+V RP+ + +R + + S A Sbjct 64 RRTDSLDPDLVAALQLDGVESVLAQCERDRKPVVTRPDRSAGWVRRALRPGKATASPSVA 123 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 A PL+S + TG+LGF+KFG R+W + E+N L +A LFAQ+QAR+ AE RLRYLA+HDD Sbjct 124 AAPLMSSDACTGVLGFVKFGARRWKQEEINTLEAVAALFAQLQARIVAEERLRYLAEHDD 183 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIG 248 LTG++NRRAL+ HL RLAPG PGPVA +LDLDRLK INDYLGH+AGD FI VFAQRI Sbjct 184 LTGVYNRRALVAHLSGRLAPGSPGPVAVFYLDLDRLKPINDYLGHSAGDWFIRVFAQRIE 243 Query 249 DALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 + S+IARLGGDEFV+IP PMS + A+ A RL L D + IGG V++RTVSIG+ Sbjct 244 ECAGTPSMIARLGGDEFVVIPDEPMSPEVAEAFARRLSTMLCDRLTIGGHVISRTVSIGL 303 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A GTPG +DLLRRAD+A L AK AGG+ A+ T DMS+ RNDIELHL+ I+S+ Sbjct 304 AVGTPGADNCADLLRRADEAVLTAKRAGGNQTAVSTDDMSLKRAFRNDIELHLQGDIDSE 363 Query 369 ALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRA 428 L L YLPEVDL TG IVG EALVRW+HP GLL P FI VAES NLA EL WV+R A Sbjct 364 GLLLHYLPEVDLWTGAIVGAEALVRWRHPVWGLLLPDSFIGVAESTNLAAELGGWVMRSA 423 Query 429 CNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVV 488 C EFS+W++ G+GH A+LRINVS QL++ GFV+ VADTIG+ G+DA+SVCLEITE VV Sbjct 424 CAEFSQWRAHGVGHGAMLRINVSPIQLISRGFVEGVADTIGEFGIDAASVCLEITERAVV 483 Query 489 QDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDL 548 D+ T R TL+ LKEVGV +AIDDFGTGY+ +S L++LP+D LKID FVR +GT+ DL Sbjct 484 HDIDTTRKTLSELKEVGVQVAIDDFGTGYAVLSHLKSLPVDMLKIDAGFVRDVGTDAGDL 543 Query 549 VIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSAR 608 IVR I+ LAE F L+VVAEGVET AAA L+ C+RAQGFL SRP+PG+AM +LSAR Sbjct 544 AIVRAIIGLAEAFGLEVVAEGVETPAAALTLMQHGCHRAQGFLLSRPLPGDAMEALLSAR 603 Query 609 RLP 611 +P Sbjct 604 WMP 606 >gi|296169849|ref|ZP_06851463.1| GGDEF protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895526|gb|EFG75226.1| GGDEF protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=625 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/611 (60%), Positives = 436/611 (72%), Gaps = 1/611 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 M +T L+ +VT+VA QLM AA++ VS++VLA LVEQ VD SFLR+ D RA Sbjct 1 MSEETVPRSLDLVVTSVATQLMEATAASAGLVSEKVLAQLVEQFDVDASFLRYLDPHTRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 + LVAEWP R + DPDP A+ V A C H ++P+V RP + ++R + Sbjct 61 SALVAEWPARTDAADPDPNAFAQLDIAESVLAQCGHGRKPVVIRPAQSKRFFRRRAGATK 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 S AA PLVSGE TTGLLGF+KFG RKW + E+N L +A LFAQVQAR+AAE +L Sbjct 121 VAASPSVAAAPLVSGETTTGLLGFVKFGARKWEQDEINTLEAVAALFAQVQARIAAEEKL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RYLA+HDDLTGL+NRRAL+ HL +RLA G+PGPVA ++LDLDRLK INDYLGH AGD FI Sbjct 181 RYLAEHDDLTGLYNRRALVAHLTERLAAGRPGPVAVMYLDLDRLKPINDYLGHTAGDWFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 VFAQRI S IARLGGDEFV++P M+ DAA+ LA RL L + +AIGG V+ Sbjct 241 RVFAQRI-RICAPNSTIARLGGDEFVVVPDQSMAPDAAESLARRLSAMLCERLAIGGHVI 299 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 +RTVSIG+A G PG+ +DLLR AD+AAL AK AGG+ +A+ T DMS+ RNDIELH Sbjct 300 SRTVSIGLAVGVPGRDNCTDLLRHADEAALTAKRAGGNQIAVSTDDMSLKRAFRNDIELH 359 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 L+ I+SDAL L YLPEVDL TG IVG EALVRW+HP GLL P FI +AES NLA EL Sbjct 360 LQGDIDSDALMLHYLPEVDLSTGAIVGAEALVRWRHPVWGLLLPDSFIGIAESTNLAMEL 419 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 RWV+R AC +FS WQ+ G+G A++RINVS QL+T GFV VA TI + G+DA SVCL Sbjct 420 GRWVMRSACADFSRWQAHGVGRGAVMRINVSPIQLITRGFVRDVAGTIEEFGIDAGSVCL 479 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITE VV D+ T R TLA LKEVGV +AIDDFGTGY+ +S L++LP+D LKID FVR Sbjct 480 EITERAVVHDIDTTRKTLAELKEVGVQLAIDDFGTGYAVLSHLKSLPVDMLKIDTGFVRD 539 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 LG + DL IVR I+ LAE F L+VVAEGVET AA IL+ C RAQGFL SRPVP +A Sbjct 540 LGNDAGDLAIVRAIIGLAEAFGLEVVAEGVETPDAAMILIQHGCRRAQGFLLSRPVPADA 599 Query 601 MRHMLSARRLP 611 M +LS R LP Sbjct 600 MEALLSTRWLP 610 >gi|342860614|ref|ZP_08717265.1| cyclic diguanylate phosphodiesterase domain-containing protein [Mycobacterium colombiense CECT 3035] gi|342132269|gb|EGT85510.1| cyclic diguanylate phosphodiesterase domain-containing protein [Mycobacterium colombiense CECT 3035] Length=621 Score = 681 bits (1757), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/603 (59%), Positives = 440/603 (73%), Gaps = 0/603 (0%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 L+ +VT+VA QLM A+T+ +VS++VLA LVEQ V+ SFLRH+ +D A+ LVAEWP Sbjct 4 SLDLVVTSVATQLMEATASTATQVSEKVLAQLVEQFDVNASFLRHHAQDAPASVLVAEWP 63 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 R + DPDP+ + A+ V A CE ++P+V RP+ +R + + + S A Sbjct 64 RRTDDADPDPVADLDLHGAESVLARCERERKPVVTRPDQPNRWIRRSLNQGKTPVSPSLA 123 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 PLVSG+ TTG+LGF+KFG RKW + E+N L +A LFAQ+QAR+AAE RLRYLA+HDD Sbjct 124 VAPLVSGDATTGVLGFVKFGARKWKQDEINTLEAVAALFAQLQARIAAEERLRYLAEHDD 183 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIG 248 LTG++NRRAL+ HL +RLA G PGPVA +LDLDRLK INDYLGH AGD FI +FAQR+ Sbjct 184 LTGVYNRRALVAHLTERLAAGSPGPVAVFYLDLDRLKPINDYLGHTAGDWFIRMFAQRLE 243 Query 249 DALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 + +S+IARLGGDEFV+IP PMS+D A+ A RL L D + IGG V++RTVSIG+ Sbjct 244 ECAGSQSMIARLGGDEFVVIPHRPMSSDDAEAFARRLSAMLCDRLTIGGHVISRTVSIGL 303 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A GTPG +DLLRRAD+A L AK AGG+ A+ T DMS+ RNDIELHL+ I+S+ Sbjct 304 AVGTPGTDNCADLLRRADEAVLTAKRAGGNQTAVSTDDMSLKRAFRNDIELHLQGDIDSE 363 Query 369 ALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRA 428 L L YLPEVDL TG IVG EALVRW+HP GLL P FI VAES NLA +L RWV+R A Sbjct 364 GLILHYLPEVDLWTGAIVGAEALVRWRHPVWGLLLPDAFIGVAESTNLAADLGRWVMRTA 423 Query 429 CNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVV 488 C EFS W++ G+G A+LRINVS QL++ GFV+ VADTI + G++A SVCLEITE VV Sbjct 424 CAEFSGWRANGVGQGAMLRINVSPIQLISRGFVESVADTIAEFGIEAESVCLEITERAVV 483 Query 489 QDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDL 548 D+ T R TLA LK+VGV IAIDDFGTGY+ +S L++LP+D LKID FVR +GTN DL Sbjct 484 HDIDTTRKTLAELKDVGVQIAIDDFGTGYAVLSHLKSLPVDMLKIDAGFVRDVGTNAGDL 543 Query 549 VIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSAR 608 IVR I+ LAE F L+VVAEGVET AAA L+ C+RAQGFL SRP+ G+AM +LSAR Sbjct 544 AIVRAIIGLAEAFGLEVVAEGVETPAAALTLMQHGCHRAQGFLLSRPIAGDAMEALLSAR 603 Query 609 RLP 611 +P Sbjct 604 WMP 606 >gi|54026890|ref|YP_121132.1| hypothetical protein nfa49160 [Nocardia farcinica IFM 10152] gi|54018398|dbj|BAD59768.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=622 Score = 676 bits (1743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/602 (57%), Positives = 429/602 (72%), Gaps = 0/602 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L+ LVT VA++LM VDA T S+RVLA LVE VD S+LRH +R+ R T LVAEWP Sbjct 6 LDSLVTQVASELMGVDATTMVASSERVLAKLVEHFDVDFSYLRHTNRENRTTVLVAEWPH 65 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R ++PDPDPLR++ FADAD VF EHA EP++ RP + DYQ I ++ G+P + A Sbjct 66 RADVPDPDPLRVVRFADADSVFRELEHATEPIIVRPGHDSADYQETIRKSSGIPKVAMAC 125 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPLVS +TG+LGFIK GDR W ELN L IA LFAQVQARV AE RLRY+A HDDL Sbjct 126 VPLVSRGESTGVLGFIKEGDRSWSTRELNVLKAIAALFAQVQARVVAEERLRYIALHDDL 185 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGL NRRALL++++ RL PG PGPVAA FLDLDRLKA+ND+LGH AGD FI + R+ + Sbjct 186 TGLANRRALLEYMEDRLRPGSPGPVAAFFLDLDRLKALNDFLGHTAGDNFIRTLSSRLRE 245 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 L +IARLGGDEFV++PA PM A AA+ A RL+ + V +GGE ++R S+GVA Sbjct 246 NLDPNDMIARLGGDEFVIVPAKPMDAVAAELEATRLQQLIGRRVTVGGESVSRGASVGVA 305 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDA 369 G PGQ T +D+LRRAD A L+AK GG+ VA+FT M EL++D+EL+LR + + Sbjct 306 VGIPGQTTVADVLRRADHALLSAKSGGGNGVAVFTDAMRAQFELQDDVELNLRGAVSDGS 365 Query 370 LRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRAC 429 L L Y PEVDLRTG IV EALVRW HPTRG+L P F+ VAE+ NLAGEL RWV+R AC Sbjct 366 LLLHYQPEVDLRTGRIVALEALVRWMHPTRGMLPPAAFVTVAEATNLAGELGRWVIRTAC 425 Query 430 NEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQ 489 +F+EW+ GL + ++RINVS QLV+ FV+ + D + G+D SSVCLEITE+VVVQ Sbjct 426 AQFAEWRRRGLAANTVMRINVSPVQLVSLDFVERIEDILRLFGIDGSSVCLEITEHVVVQ 485 Query 490 DLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLV 549 DL + TL LK +GV IAIDDFGTGYS++S L+ LP+D +KID+ FV++LG +T DL Sbjct 486 DLARTQVTLRGLKRMGVQIAIDDFGTGYSSLSHLKALPVDAVKIDRGFVQRLGASTDDLA 545 Query 550 IVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARR 609 IV+ I+ LA F L VV EGVET AAR L+ CYRAQGFL +RP+P + + L R Sbjct 546 IVKSIIGLAGSFGLGVVGEGVETAVAARTLVGLGCYRAQGFLIARPMPADEVEAHLVTGR 605 Query 610 LP 611 +P Sbjct 606 IP 607 >gi|118465484|ref|YP_882316.1| GGDEF domain-containing protein [Mycobacterium avium 104] gi|118166771|gb|ABK67668.1| GGDEF domain protein [Mycobacterium avium 104] Length=621 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/604 (60%), Positives = 437/604 (73%), Gaps = 4/604 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L+ LVT A +LM AA +A++S+RVLA LV GV+ FLRHND RAT LVAEWPP Sbjct 5 LDHLVTAAAAELMAATAADAAQISERVLADLVSHFGVNFGFLRHNDHSIRATVLVAEWPP 64 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R N+ DPDPL +IYFADAD VFA E KEP V RPEPA DYQR IE+ G+P S AA Sbjct 65 R-NV-DPDPLGVIYFADADSVFARVETMKEPDVLRPEPANADYQRNIEDGTGIPEVSLAA 122 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPL+SG++TTG LGF+KFGDR+W ELNAL IA LFAQ+QARV AE ++ YLA+HD+L Sbjct 123 VPLLSGDVTTGTLGFVKFGDREWLSEELNALQAIAALFAQLQARVVAEEQIHYLAEHDEL 182 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGL NRRAL+ HLD+RLAPGQPGPV +FL +DR K IN LG AGD+FI FA + + Sbjct 183 TGLLNRRALIAHLDKRLAPGQPGPVPVVFLAIDRFKVINGRLGQDAGDRFIDAFAALLRE 242 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 A S+IAR GGDEF ++PA+PM +AA+ A L ++L +AI E+L+RTVSIGVA Sbjct 243 ATEIPSVIARFGGDEFGVVPAAPMDVEAAESFAHSLHERLHHPIAIDDEMLSRTVSIGVA 302 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE--S 367 +G PG + SDLLRR DQA +AK AGG++VA F +MS +RNDIEL+L I+ S Sbjct 303 AGIPGDESTSDLLRRVDQATRSAKAAGGNNVATFRPEMSTIDTIRNDIELYLEGMIDGGS 362 Query 368 DALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRR 427 AL L YLPE D+RTG+I+GTEAL RWQHPT GLL P FI VAESINL +L R V+R Sbjct 363 GALVLHYLPEFDMRTGEILGTEALTRWQHPTLGLLMPDSFIQVAESINLGAKLGRLVMRS 422 Query 428 ACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVV 487 AC +F +W+S G+G +LRINVS QLVT G VD VA T+ + GLD S+VCLEITE+VV Sbjct 423 ACAQFGQWRSRGVGQGTVLRINVSPVQLVTAGIVDTVAATLDEFGLDPSTVCLEITESVV 482 Query 488 VQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSD 547 VQD+ R TL LK++GV IAIDDFGTGYS ++ L++LP+D+LKIDK FV+ L TN D Sbjct 483 VQDIDATRQTLFGLKDIGVQIAIDDFGTGYSVLTYLKSLPVDSLKIDKGFVQSLDTNPGD 542 Query 548 LVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSA 607 L IVR + LA+ F LDVVAEGVET AAA LL C+RAQGFL SRP+ M +L Sbjct 543 LAIVRSTLALADAFGLDVVAEGVETVAAAETLLSLGCHRAQGFLLSRPLDSAGMEALLIK 602 Query 608 RRLP 611 +P Sbjct 603 GAIP 606 >gi|254775582|ref|ZP_05217098.1| GGDEF domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] Length=621 Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/604 (60%), Positives = 436/604 (73%), Gaps = 4/604 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L+ LVT A +LM AA +A++S+RVLA LV GV+ FLRHND RAT LVAEWPP Sbjct 5 LDHLVTAAAAELMAATAADAAQISERVLADLVSHFGVNFGFLRHNDHSIRATVLVAEWPP 64 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R N+ DPDPL +IYFADAD VFA E KEP V RPEPA DYQR IE+ G+P S AA Sbjct 65 R-NV-DPDPLGVIYFADADSVFARVETMKEPDVLRPEPANADYQRNIEDGTGIPEVSLAA 122 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPL+SG++TTG LGF+KFGDR+W ELNAL IA LFAQ+QARV AE ++ YLA+HD+L Sbjct 123 VPLLSGDVTTGTLGFVKFGDREWLSEELNALQAIAALFAQLQARVVAEEQIHYLAEHDEL 182 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGL NRRAL+ HLD+RLAPGQPGPV +FL +DR K IN LG AGD+FI FA + + Sbjct 183 TGLLNRRALIAHLDKRLAPGQPGPVPVVFLAIDRFKVINGRLGQDAGDRFIDAFAALLRE 242 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 A S+IAR GGDEF ++PA+PM +AA+ A L ++L +AI E+L+RTVSIGVA Sbjct 243 ATEIPSVIARFGGDEFGVVPAAPMDVEAAESFAHSLHERLHHPIAIDDEMLSRTVSIGVA 302 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE--S 367 +G PG + SDLLRR DQA +AK AGG++VA F +MS +RNDIEL+L I+ S Sbjct 303 AGIPGDESTSDLLRRVDQATRSAKAAGGNNVATFRPEMSTIDTIRNDIELYLEGMIDGGS 362 Query 368 DALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRR 427 AL L YLPE D+RTG+I+G EAL RWQHPT GLL P FI VAESINL +L R V+R Sbjct 363 GALVLHYLPEFDMRTGEILGIEALTRWQHPTLGLLMPDSFIQVAESINLGAKLGRLVMRS 422 Query 428 ACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVV 487 AC +F +W+S G+G +LRINVS QLVT G VD VA T+ + GLD S+VCLEITE+VV Sbjct 423 ACAQFGQWRSRGVGQGTVLRINVSPVQLVTAGIVDTVAATLDEFGLDPSTVCLEITESVV 482 Query 488 VQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSD 547 VQD+ R TL LK++GV IAIDDFGTGYS ++ L++LP+D+LKIDK FV+ L TN D Sbjct 483 VQDIDATRQTLFGLKDIGVQIAIDDFGTGYSVLTYLKSLPVDSLKIDKGFVQSLDTNPGD 542 Query 548 LVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSA 607 L IVR + LA+ F LDVVAEGVET AAA LL C+RAQGFL SRP+ M +L Sbjct 543 LAIVRSTLALADAFGLDVVAEGVETVAAAETLLSLGCHRAQGFLLSRPLDSAGMEALLIK 602 Query 608 RRLP 611 +P Sbjct 603 GAIP 606 >gi|118462879|ref|YP_880384.1| cyclic diguanylate phosphodiesterase domain-containing protein [Mycobacterium avium 104] gi|254774008|ref|ZP_05215524.1| cyclic diguanylate phosphodiesterase domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118164166|gb|ABK65063.1| cyclic diguanylate phosphodiesterase (EAL) domain protein [Mycobacterium avium 104] Length=617 Score = 669 bits (1727), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/603 (59%), Positives = 430/603 (72%), Gaps = 4/603 (0%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 L+ +VT+VA LM A+T+ VS+ VLA LVEQ VD SFL H+D VAEWP Sbjct 4 SLDLVVTSVATALMEATASTARSVSETVLAQLVEQFDVDASFLHHHDAAGPVP--VAEWP 61 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 R + P + + D + V A CE + P+V P+ A +R ++ + S A Sbjct 62 RRTDAAGP--MAALRSEDVESVLAQCERQRRPVVSSPDQADGWLRRWLQRDKAAGAPSVA 119 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 A PLVSG+ TTG+LGF+KFG R+W E+N L +A LFAQ+QAR+AAE RLRYLA+HDD Sbjct 120 AAPLVSGDATTGVLGFVKFGARRWKPEEINTLEAVAALFAQLQARIAAEERLRYLAEHDD 179 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIG 248 LTG++NRRAL+ HL +RLA G PGPVA +LDLDRLK INDYLGH AGD FI VFAQRI Sbjct 180 LTGVYNRRALVAHLTERLAAGNPGPVAVFYLDLDRLKPINDYLGHTAGDWFIRVFAQRIE 239 Query 249 DALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 + +S+IARLGGDEFV+IP PM+++AA+ A RL L D + IGG V++RTVSIG+ Sbjct 240 ECAGEQSMIARLGGDEFVVIPHQPMASEAAEAFARRLSTLLCDRLTIGGHVISRTVSIGL 299 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A GTPG +DLLRRAD+A L AK AGG+ A+ T DMS+ RNDIELHL+ IES+ Sbjct 300 AVGTPGADNCTDLLRRADEAVLTAKRAGGNQTAVSTDDMSLKRAFRNDIELHLQGDIESE 359 Query 369 ALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRA 428 L L YLPEVDL TG +VG EALVRW+HP GLL P FI VAES NL EL WV+R A Sbjct 360 GLLLHYLPEVDLWTGAVVGAEALVRWRHPIWGLLLPDSFIGVAESTNLGAELGGWVMRSA 419 Query 429 CNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVV 488 C +FS W++ G+GH A+LRINVS QL++ GFV+ VADTIG+ G+DA SVCLEITE VV Sbjct 420 CADFSRWRANGVGHGAMLRINVSPIQLISRGFVETVADTIGEFGIDAGSVCLEITERAVV 479 Query 489 QDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDL 548 D T R TL+ LKEVGV IAIDDFGTGY+ +S L++LP+D LKID FVR++GT+ DL Sbjct 480 HDTETTRKTLSELKEVGVQIAIDDFGTGYAVLSHLKSLPVDMLKIDAGFVREVGTDAGDL 539 Query 549 VIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSAR 608 IVR I+ LAE F L+VVAEGVET AAA L+ C+RAQGFL SRP+PGEAM +LSAR Sbjct 540 AIVRAIIGLAEAFGLEVVAEGVETPAAALTLMQHGCHRAQGFLLSRPIPGEAMEALLSAR 599 Query 609 RLP 611 +P Sbjct 600 WMP 602 >gi|254820324|ref|ZP_05225325.1| GGDEF domain-containing protein [Mycobacterium intracellulare ATCC 13950] Length=621 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/619 (58%), Positives = 433/619 (70%), Gaps = 8/619 (1%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L+ LVT A +LM AA SA +S+RVL LV LGVD SFLRHND RAT L+AE+PP Sbjct 5 LDHLVTAAAAELMAATAADSASISERVLGNLVRDLGVDFSFLRHNDHTIRATILIAEFPP 64 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R DPDP+ L+YFADAD +FA EH K P V RPEP DYQ IE GVP S AA Sbjct 65 R--NADPDPIGLVYFADADSIFARTEHLKVPEVVRPEPENADYQNRIEAGTGVPAVSLAA 122 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPL+SG++TTG L F K GDR+W ELNAL IA LFAQ+QARV AE ++ YLA+HD+L Sbjct 123 VPLLSGDVTTGTLAFGKLGDREWLPEELNALQAIAALFAQLQARVVAEQQIHYLAEHDEL 182 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGL NRRAL+ HLD RLA GQPGPV+ +FL +DR K IN LG AGD+FI FA + + Sbjct 183 TGLLNRRALIAHLDDRLAKGQPGPVSVVFLAIDRFKVINSRLGQDAGDRFIESFAALLRE 242 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 A S+IAR GGDEF ++P++ M +AA+ A L ++ + I GE+L+RTVSIGVA Sbjct 243 ATRVPSVIARFGGDEFGVVPSAAMDVEAAEAFAHSLHGRVHQQIPIDGEMLSRTVSIGVA 302 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIE--S 367 +G PG T SDLLRR DQA +AK +GG++VA F +MS + +RNDIELHL IE Sbjct 303 AGLPGDETTSDLLRRVDQATRSAKASGGNNVATFRPEMSTTDMIRNDIELHLEGMIEGGG 362 Query 368 DALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRR 427 AL L YLPE D+RTG+I+GTEAL+RWQHPT GLL P FI V ESINL +L R V+R Sbjct 363 GALVLHYLPEFDMRTGEILGTEALIRWQHPTLGLLMPDSFIQVVESINLGAKLGRLVMRS 422 Query 428 ACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVV 487 AC +F W+S G+G +LRINVS QLVT G VD VA T+ + GLD S+VCLEITE+VV Sbjct 423 ACAQFGLWRSHGVGKGTVLRINVSPVQLVTAGIVDTVAATLDEFGLDPSTVCLEITESVV 482 Query 488 VQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSD 547 VQD+ R TL LK+VGV IAIDDFGTGYS ++ L++LP+D+LKIDK FV+ L TN D Sbjct 483 VQDIDATRQTLFGLKDVGVQIAIDDFGTGYSVLTYLKSLPVDSLKIDKGFVQNLDTNAGD 542 Query 548 LVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSA 607 L IVR M LA+ F LDVVAEGVET AAA LL C+RAQGFL SRP+ AM +L+ Sbjct 543 LAIVRSTMALADAFGLDVVAEGVETVAAAERLLSLGCHRAQGFLLSRPIDSAAMESLLAK 602 Query 608 RRLP----PTCIPATDPAL 622 R +P T P T A+ Sbjct 603 RVIPMNFSSTRFPGTGNAV 621 >gi|41407047|ref|NP_959883.1| hypothetical protein MAP0949 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395398|gb|AAS03266.1| hypothetical protein MAP_0949 [Mycobacterium avium subsp. paratuberculosis K-10] Length=617 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/603 (58%), Positives = 428/603 (71%), Gaps = 4/603 (0%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 L+ +VT+VA LM A+T+ VS+ VLA LVEQ VD SFL H+D VAEWP Sbjct 4 SLDLVVTSVATALMEATASTARSVSETVLAQLVEQFDVDASFLHHHDAAGPVP--VAEWP 61 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 R + P + + D + V A CE + P+V P+ +R ++ + S A Sbjct 62 RRTDAAGP--MAALRSEDVESVLAQCERQRRPVVSSPDRVDGWLRRWLQRDKAAGAPSVA 119 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 A PLVSG+ TTG+LGF+KFG R+W E+N L +A LFAQ+QAR+AAE RLRYLA+HDD Sbjct 120 AAPLVSGDATTGVLGFVKFGARRWKPEEINTLEAVAALFAQLQARIAAEERLRYLAEHDD 179 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIG 248 LTG++NRRAL+ HL +RLA G PGPVA +LDLDRLK INDYLGH AGD FI VFAQRI Sbjct 180 LTGVYNRRALVAHLTERLAAGNPGPVAVFYLDLDRLKPINDYLGHTAGDWFIRVFAQRIE 239 Query 249 DALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 + +S+IARLGGDEFV+IP PM+++AA+ A RL L D + IGG V++RTVSIG+ Sbjct 240 ECAGEQSMIARLGGDEFVVIPHQPMASEAAEAFARRLSTLLCDRLTIGGHVISRTVSIGL 299 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A GTPG +DLLRRAD+A L AK AGG+ A+ T DMS+ RNDIELHL+ IES+ Sbjct 300 AVGTPGADNCTDLLRRADEAVLTAKRAGGNQTAVSTDDMSLKRAFRNDIELHLQGDIESE 359 Query 369 ALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRA 428 L L YLPEVDL TG +VG EALVRW+HP GLL P FI VAES NL EL V+R A Sbjct 360 GLLLHYLPEVDLWTGAVVGAEALVRWRHPIWGLLLPDSFIGVAESTNLGAELGGGVMRSA 419 Query 429 CNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVV 488 C +FS W++ G+GH A+LRINVS QL++ GFV+ VADTIG+ G+DA SVCLEITE VV Sbjct 420 CADFSRWRANGVGHGAMLRINVSPIQLISRGFVETVADTIGEFGIDAGSVCLEITERAVV 479 Query 489 QDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDL 548 D T R TL+ LKEVGV IAIDDFGTGY+ +S L++LP+D LKID FVR++GT+ DL Sbjct 480 HDTETTRKTLSELKEVGVQIAIDDFGTGYAVLSHLKSLPVDMLKIDAGFVREVGTDAGDL 539 Query 549 VIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSAR 608 IVR I+ LAE F L+VVAEGVET AAA L+ C+RAQGFL SRP+PGEAM +LSAR Sbjct 540 AIVRAIIGLAEAFGLEVVAEGVETPAAALTLMQHGCHRAQGFLLSRPIPGEAMEALLSAR 599 Query 609 RLP 611 +P Sbjct 600 WMP 602 >gi|342860779|ref|ZP_08717429.1| GGDEF domain-containing protein [Mycobacterium colombiense CECT 3035] gi|342131803|gb|EGT85060.1| GGDEF domain-containing protein [Mycobacterium colombiense CECT 3035] Length=622 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/605 (59%), Positives = 428/605 (71%), Gaps = 5/605 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L+ LVT A +LM AA SA VSQRVL LV +L VD SFLRHND RAT LVAEWPP Sbjct 5 LDYLVTGAAAELMAATAADSAAVSQRVLGDLVRELAVDFSFLRHNDHTIRATVLVAEWPP 64 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R DPDP+ +IYF+DAD VFA EH K P V RP PA EDYQR I+E G S AA Sbjct 65 R--NADPDPIGVIYFSDADSVFAQAEHLKVPQVVRPAPANEDYQRNIDEGTGWGTVSLAA 122 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPL+SG++TTG L F K GDR+W ELNA+ IA LFAQ+QARV AE ++ YLA+HD+L Sbjct 123 VPLLSGDVTTGTLAFGKVGDREWLPEELNAVQAIAALFAQLQARVVAEEQIHYLAEHDEL 182 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 TGL NRRAL+ +LD+RLA G+PGPV+ +F+ LDR K IND LG AGD+FI FA + + Sbjct 183 TGLLNRRALIAYLDKRLAEGRPGPVSVVFVSLDRFKVINDRLGQDAGDRFIVAFAALLRE 242 Query 250 ALVGES-LIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 A S +IAR GGDEFV++P PM DAA+ A L +QL V+I GE+L+RTVSIGV Sbjct 243 ATDAVSTVIARFGGDEFVVVPTGPMDVDAAEAFARSLHNQLHGQVSIDGEMLSRTVSIGV 302 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A+G PG + SDLLRR DQA + K +GG+ +A F+ +MS + +RNDIELHL +S Sbjct 303 AAGVPGHESTSDLLRRVDQATRSVKGSGGNKLATFSPEMSTTDMIRNDIELHLEGTTDSG 362 Query 369 ALRLV--YLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLR 426 LV YLPE D+ TG I+GTEAL+RWQHPT GLL P FI V ESINL +L R V+R Sbjct 363 IGTLVLHYLPEFDMNTGAILGTEALIRWQHPTLGLLMPDSFIQVVESINLGAKLGRLVMR 422 Query 427 RACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENV 486 AC +F WQS G+GH +LR+NVS QLVT G V VA T+ + L+ S+VCLEITE+V Sbjct 423 SACAQFGLWQSRGVGHGTVLRVNVSPVQLVTDGIVGAVAATLDEFNLNPSTVCLEITESV 482 Query 487 VVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTS 546 VVQD+ R TL LK++GV IAIDDFGTGYS ++ L++LP+D LKIDK FVR L TN Sbjct 483 VVQDIDATRKTLFGLKDIGVQIAIDDFGTGYSVLTYLKSLPVDALKIDKGFVRNLDTNAG 542 Query 547 DLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLS 606 DL IVR M LAE F L+VVAEGVET AAA+ LL C+RAQGFL SRP+ AM +L+ Sbjct 543 DLAIVRSTMALAEAFGLEVVAEGVETVAAAKTLLSLGCHRAQGFLLSRPLDNSAMESLLT 602 Query 607 ARRLP 611 R +P Sbjct 603 KRVVP 607 >gi|333990223|ref|YP_004522837.1| hypothetical protein JDM601_1583 [Mycobacterium sp. JDM601] gi|333486191|gb|AEF35583.1| conserved hypothetical protein [Mycobacterium sp. JDM601] Length=613 Score = 659 bits (1700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/598 (58%), Positives = 416/598 (70%), Gaps = 0/598 (0%) Query 13 LVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLN 72 LVT++A QLM AT+ VS+RVL LVEQL VD FLRHND + RA++LVAEWPPR + Sbjct 3 LVTSIAAQLMATTPATAPAVSERVLQTLVEQLNVDAGFLRHNDHEIRASKLVAEWPPRTD 62 Query 73 IPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPL 132 PDPDPL ++ F ADPVF C H K V RPEP+ Y R + + S A PL Sbjct 63 PPDPDPLAVVSFTTADPVFTTCAHGKRVAVIRPEPSESGYVRQLAIDHAIESLSVATAPL 122 Query 133 VSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGL 192 +SG +TTG+LG +KF KW ELN + IA+LFAQ+QARV AE RLRYLADHDDLTGL Sbjct 123 ISGPVTTGMLGLVKFRRPKWRPEELNTIEAIASLFAQLQARVVAEERLRYLADHDDLTGL 182 Query 193 HNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALV 252 HNRRAL+ HL RL G PGPV ++DLDRLK INDYLGHAAGD FI FA+R+ Sbjct 183 HNRRALVAHLSDRLVAGNPGPVGVFYIDLDRLKPINDYLGHAAGDWFIQDFARRLRAYAG 242 Query 253 GESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGT 312 ++ AR+GGDEFV+IP PMS +A+ A+RL+ L+D V I G +T TVS+GV G Sbjct 243 NRTMTARIGGDEFVVIPDWPMSMASAETFADRLQGALRDKVEIQGHTVTSTVSVGVTVGL 302 Query 313 PGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRL 372 PG+ T + LL RAD+A LAAK GG+ T DMS+ R DIELHL+ I+ ++L L Sbjct 303 PGEDTSAGLLHRADEAVLAAKRGGGNQTVSSTDDMSLKSLFRKDIELHLQGKIDDESLLL 362 Query 373 VYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEF 432 Y PEVDL +G IV EALVRW+HPTRGLL PG FI +AES NLA +L RWV+R AC EF Sbjct 363 YYQPEVDLWSGAIVAVEALVRWRHPTRGLLLPGSFISIAESANLADDLGRWVMRSACAEF 422 Query 433 SEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLH 492 S WQ+ G+ +A LR+NVS QL GFV V DT+ + GL S+CLEITE VVQ++ Sbjct 423 SSWQANGVRTNATLRVNVSPVQLAARGFVQNVVDTVEEFGLRPGSLCLEITERAVVQNIE 482 Query 493 TARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVR 552 T R TLA L+E GV IAIDDFGTGY+ +S L+ LP+DTLKID FVR+LG N DL IVR Sbjct 483 TTRRTLAELREAGVQIAIDDFGTGYAVLSHLKDLPVDTLKIDTVFVRELGVNAGDLAIVR 542 Query 553 GIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRL 610 I+ LAE F L VVAEGVET AAA L+ C+RAQGFLFSRPVPG A ML++R + Sbjct 543 AIIALAEAFGLQVVAEGVETSAAALTLMRHGCHRAQGFLFSRPVPGAAAESMLASRWM 600 >gi|226365224|ref|YP_002783007.1| hypothetical protein ROP_58150 [Rhodococcus opacus B4] gi|226243714|dbj|BAH54062.1| hypothetical protein [Rhodococcus opacus B4] Length=614 Score = 638 bits (1646), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/607 (55%), Positives = 411/607 (68%), Gaps = 0/607 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 M + T +LE LVTTVA++L VDA + V+ RVL LVE VD SFLR D + A Sbjct 1 MNTEKQTEKLETLVTTVASRLTPVDAVSFKAVATRVLQDLVEHFEVDTSFLRFTDHEIAA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 T LVAE+P R IPDPDPL ++YF DADP FA EH KE +FRPE + DY + EA Sbjct 61 TVLVAEYPLRPFIPDPDPLGVVYFKDADPTFAQIEHQKEVAIFRPEVSGPDYNERVREAS 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVP S AAVPL+SGE TTG LGFIKFGDR W EL+ L IA L AQVQAR+ E +L Sbjct 121 GVPQVSLAAVPLLSGETTTGTLGFIKFGDRDWTPPELDVLKAIAALLAQVQARIVVEEQL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RY ADHD LTGL NRRAL HLD RLA +PGPVA LFLDLDRLK +ND+ GH AGD FI Sbjct 181 RYSADHDSLTGLSNRRALYHHLDTRLASSEPGPVAILFLDLDRLKPLNDFFGHGAGDGFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 A R+ + L++RLGGDEFVL+ + + A+ A+ +RD + + V +G EV+ Sbjct 241 STIADRLRSTSDADDLVSRLGGDEFVLVLGGSVGLEEAEVRAQHIRDVVTERVRLGREVV 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 +R+VSIGVA+G PG+ T S LL +ADQA + AK GG+++++FT +M E RN IEL Sbjct 301 SRSVSIGVAAGCPGKATTSSLLSQADQAVMVAKTKGGNAISVFTDEMQEESEKRNMIELS 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 LR I ++L L Y PEVDLRTG I+G EALVRW HP GLL PG FI VAE+ N+AGEL Sbjct 361 LRAAIADESLFLEYQPEVDLRTGRIIGVEALVRWNHPLLGLLQPGSFIDVAEATNVAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 RWV+R+AC ++++W+S D L +NVS GQL F+D V D + + L ++CL Sbjct 421 GRWVIRKACRQWADWRSQAPELDLALAVNVSPGQLAGLDFLDVVRDALAEFDLRKGALCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITEN V+ DL R L L + V +AIDDFGTGYS++S L+ LP+ TLKIDK FV Sbjct 481 EITENAVLSDLTWTREALEGLHAMDVEVAIDDFGTGYSSLSHLKALPVGTLKIDKGFVMN 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 L TN D IV+ I+ LAE F L++VAEGVE +AR LLD CYRAQGFLFSRPV E Sbjct 541 LDTNPGDRAIVKSIIGLAESFGLELVAEGVENVESARQLLDMGCYRAQGFLFSRPVSAEE 600 Query 601 MRHMLSA 607 + +L+A Sbjct 601 IGKLLAA 607 >gi|111022717|ref|YP_705689.1| hypothetical protein RHA1_ro05753 [Rhodococcus jostii RHA1] gi|110822247|gb|ABG97531.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=614 Score = 623 bits (1607), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 327/607 (54%), Positives = 409/607 (68%), Gaps = 0/607 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 M + T +LE LVTTVA++L VDA + V+ RVL LVE VD SFLR D + A Sbjct 1 MNTEKQTEKLETLVTTVASRLTPVDAVSFKPVATRVLQDLVEHFEVDTSFLRFTDHEIAA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 T LVAE+P R IPDPDPL ++YF DAD FA EH KE +FRPE + DY + EA Sbjct 61 TVLVAEYPLRPFIPDPDPLGIVYFKDADSTFAQIEHQKEVAIFRPEVSGPDYNERVREAS 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVP S AAVPL+SG+ TTG LGFIKFGDR W EL+ L IA L AQVQAR+ E +L Sbjct 121 GVPQVSLAAVPLLSGDTTTGTLGFIKFGDRDWTPPELDVLKAIAALLAQVQARIVVEEQL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFI 240 RY ADHD LTGL NRRAL HLD RLA + GPVA LFLDLDRLK +ND+ GH AGD FI Sbjct 181 RYSADHDSLTGLSNRRALYHHLDTRLAESEAGPVAILFLDLDRLKPLNDFFGHGAGDGFI 240 Query 241 HVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVL 300 A R+ + L++RLGGDEFVL+ + + A+ A+ +RD + + V +G EV+ Sbjct 241 STIADRLRSTSQTDDLVSRLGGDEFVLVLGGSVGLEEAEVRAQHIRDVVTERVRLGREVV 300 Query 301 TRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELH 360 +R+VSIGVA G PG+ T S LL +ADQA + AK GG+++++FT +M E RN IEL Sbjct 301 SRSVSIGVAVGIPGKATTSSLLSQADQAVMVAKTKGGNAISVFTDEMQEESEKRNMIELS 360 Query 361 LRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 LR I ++L L Y PEVDLRTG I+G EALVRW HP GLL P FI VAE+ N+AGEL Sbjct 361 LRAAIADESLFLEYQPEVDLRTGRIIGVEALVRWNHPLLGLLQPASFIDVAEATNVAGEL 420 Query 421 DRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCL 480 RWV+R+AC ++++W+S D LR+NVS GQL F+D VA+ + + L ++CL Sbjct 421 GRWVIRKACRQWADWRSQVPELDLDLRVNVSPGQLAGLDFLDVVANALTEFDLRKGALCL 480 Query 481 EITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQ 540 EITEN V+ DL R L L + V +AIDDFGTG+S++S L+ LP+ TLKIDK FV Sbjct 481 EITENAVLSDLTWTREALEGLHAMDVEVAIDDFGTGFSSLSHLKALPVGTLKIDKGFVMN 540 Query 541 LGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEA 600 L TN D IV+ I+ LAE F L++VAEGVE +AR LLD C+RAQGFLFSRPV E Sbjct 541 LDTNPEDRAIVKSIIGLAESFGLELVAEGVENVESARQLLDMGCHRAQGFLFSRPVSAEK 600 Query 601 MRHMLSA 607 + +L+A Sbjct 601 IGKLLAA 607 >gi|258650469|ref|YP_003199625.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Nakamurella multipartita DSM 44233] gi|258553694|gb|ACV76636.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Nakamurella multipartita DSM 44233] Length=659 Score = 579 bits (1492), Expect = 6e-163, Method: Compositional matrix adjust. Identities = 309/610 (51%), Positives = 394/610 (65%), Gaps = 7/610 (1%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 LEELVT A LM V A + +Q +L LV+ GVD SFLR ND A+ LVAEWPP Sbjct 7 LEELVTQAATDLMGVTAVSLRGATQNLLRELVDYFGVDTSFLRRNDHQIHASLLVAEWPP 66 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRP------EPATEDYQRLIEEARGVP 123 R+++PDPDPL L+YF ADP FA E + RP E DYQ L+ A GV Sbjct 67 RIDVPDPDPLALVYFEGADPTFAASETLSHVTITRPGELFGAEVDDSDYQELVRRASGVQ 126 Query 124 V-TSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRY 182 + S A VP++ T G+LGF+K+GDR+W +AE+NAL +A L AQ+QARV AE RLR+ Sbjct 127 IGVSLAVVPMLGTHDTMGVLGFVKYGDREWTDAEINALRAVAGLLAQLQARVDAEERLRH 186 Query 183 LADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHV 242 A HD+LT L NRR L++ + QRL PG PV +F+D+DRLKA+N + GHAAGDQ++ + Sbjct 187 QAFHDELTDLANRRFLVEEITQRLEPGTGDPVGLIFMDVDRLKALNSFFGHAAGDQYLQI 246 Query 243 FAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTR 302 A R+ + + ++ARLGGDEFV+I P A+ LAE+LR + +GGE ++R Sbjct 247 LAGRLRERISARHMVARLGGDEFVVIMGGPTDEATARALAEKLRQVANQPILVGGEEVSR 306 Query 303 TVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLR 362 VSIGVA G PGQ + S+L+ +ADQA L AK GG+ + +F+A M + E+R DIELH+ Sbjct 307 AVSIGVALGQPGQTSASELMNQADQAMLEAKSRGGNEIGVFSAQMRRANEIRTDIELHIG 366 Query 363 RGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDR 422 I AL L Y PEVDLR G I+G EALVRW +PT GLL PG FI V E+ NLAGEL R Sbjct 367 TAIRHGALVLHYQPEVDLRDGRILGVEALVRWPNPTLGLLQPGAFIDVVEATNLAGELGR 426 Query 423 WVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEI 482 WVL +AC + EWQ + +NVS QL+T FV VA T+ H LD + LEI Sbjct 427 WVLGQACRQLREWQLHYPERRLGMSVNVSPAQLITLDFVATVAKTLADHELDGQWLTLEI 486 Query 483 TENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLG 542 TE +V+D A ATL L+ +GV IAIDDFGTGYS+ + L++LP D LKID+ FVR LG Sbjct 487 TEQALVRDTDQALATLRGLQRIGVKIAIDDFGTGYSSFAQLKSLPADVLKIDRGFVRDLG 546 Query 543 TNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMR 602 T+ DL IV+ I+ LA LD+VAEGVETE AA L+D C RAQGFLF+ P P + Sbjct 547 TDFDDLAIVQSIIGLARSLGLDLVAEGVETEIAASTLVDLGCTRAQGFLFAGPRPPAEIE 606 Query 603 HMLSARRLPP 612 M+ PP Sbjct 607 QMIQTGVCPP 616 >gi|258655343|ref|YP_003204499.1| GAF sensor-containing diguanylate cyclase/phosphodiesterase [Nakamurella multipartita DSM 44233] gi|258558568|gb|ACV81510.1| diguanylate cyclase/phosphodiesterase with GAF sensor [Nakamurella multipartita DSM 44233] Length=626 Score = 561 bits (1445), Expect = 2e-157, Method: Compositional matrix adjust. Identities = 306/600 (51%), Positives = 394/600 (66%), Gaps = 2/600 (0%) Query 10 LEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPP 69 L++LVT+VA +LM V + S+ +L LV+ VD+SFLR ND + AT LVAEWPP Sbjct 5 LDDLVTSVATELMGVTISNLEAASRDLLHRLVDYFEVDLSFLRRNDHELGATVLVAEWPP 64 Query 70 RLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAA 129 R +IPDPDPL +IYFA ADP FA E+ K + RP E YQ + + G+ S A Sbjct 65 REDIPDPDPLGVIYFAGADPTFAALENLKSVMTQRPS-NDEKYQDRVRQGSGIQEVSLAT 123 Query 130 VPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDL 189 VPL++ + TTG LGFIK+GDR+W E+NAL +A L AQ+QARVAAE RL YLA HD+L Sbjct 124 VPLMTNDTTTGTLGFIKYGDREWLHDEINALQAVAALLAQLQARVAAEERLHYLAYHDEL 183 Query 190 TGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGD 249 T L RR L HL +RL PG PGPVA +F+D+DRLKA+N +LGHAAGDQ++H A R+ + Sbjct 184 TTLATRRGLTDHLAKRLKPGAPGPVAVIFIDVDRLKALNSFLGHAAGDQYLHTLAHRLRE 243 Query 250 ALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVA 309 A+ + L+ARLGGDEFV + P + A+ AERLR V +GGE +TR VS+GVA Sbjct 244 AMPNDQLLARLGGDEFVSVILGPADEERARECAERLRIAANQPVQVGGEEITRGVSVGVA 303 Query 310 SGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDA 369 G PG S+L+ +ADQA L AK GG++V FTA+M E+R DIELHL + +D+ Sbjct 304 LGVPGAADVSELMNQADQAMLQAKGNGGNAVCFFTAEMRRQNEIRTDIELHLVTAVRNDS 363 Query 370 LRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRAC 429 L L + P+V L +G I G EALVRW HP GLL P FI V E+ NLAGEL RWV+ C Sbjct 364 LVLFFQPQVALESGTIDGVEALVRWPHPNLGLLPPSAFIDVIETTNLAGELGRWVIESGC 423 Query 430 NEFSEWQSAGLGHDAL-LRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVV 488 + W + L + +NVS +L+T FV V T+ + GLD + LEITE +V Sbjct 424 RQLKAWHDRFPKDEPLTMSVNVSPAELLTTDFVATVRRTLVETGLDGQYLTLEITEKALV 483 Query 489 QDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDL 548 +D A TL LKE+GV +AIDDFGTGYS+ + L+ LP+D LKID+TFV +LG N++DL Sbjct 484 RDTEQALLTLRGLKEIGVKVAIDDFGTGYSSFAQLRALPVDELKIDRTFVSELGHNSNDL 543 Query 549 VIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSAR 608 IVR I+ LA+ F L++VAEGVETE AA L+ C RAQGFLF P + +L R Sbjct 544 AIVRSIIGLADAFDLEIVAEGVETEVAAATLIALGCRRAQGFLFGAPRSAADLTTILDQR 603 >gi|294994911|ref|ZP_06800602.1| hypothetical protein Mtub2_10468 [Mycobacterium tuberculosis 210] Length=214 Score = 433 bits (1114), Expect = 4e-119, Method: Compositional matrix adjust. Identities = 213/214 (99%), Positives = 214/214 (100%), Gaps = 0/214 (0%) Query 410 VAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIG 469 +AESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIG Sbjct 1 MAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIG 60 Query 470 QHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPID 529 QHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPID Sbjct 61 QHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPID 120 Query 530 TLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQG 589 TLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQG Sbjct 121 TLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQG 180 Query 590 FLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS 623 FLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS Sbjct 181 FLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS 214 >gi|294994912|ref|ZP_06800603.1| hypothetical protein Mtub2_10475 [Mycobacterium tuberculosis 210] Length=236 Score = 431 bits (1109), Expect = 1e-118, Method: Compositional matrix adjust. Identities = 211/212 (99%), Positives = 211/212 (99%), Gaps = 0/212 (0%) Query 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA Sbjct 1 MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRA 60 Query 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR Sbjct 61 TRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEAR 120 Query 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL Sbjct 121 GVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARL 180 Query 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPG 212 RYLADHDDLTGLHNRRALLQHLDQRLAPGQP Sbjct 181 RYLADHDDLTGLHNRRALLQHLDQRLAPGQPA 212 >gi|336457797|gb|EGO36791.1| diguanylate cyclase (GGDEF) domain-containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=407 Score = 426 bits (1094), Expect = 9e-117, Method: Compositional matrix adjust. Identities = 227/408 (56%), Positives = 281/408 (69%), Gaps = 3/408 (0%) Query 217 LFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSAD 276 +FL +DR K IN LG AGD+FI FA I + S+IAR GGDEFV++P +PM + Sbjct 1 MFLAVDRFKVINGRLGQHAGDRFIEAFAALIRQTIDIPSVIARFGGDEFVVVPEAPMDVE 60 Query 277 AAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAG 336 AA+ A L L V I E+L+RTVSIGVA+G PG T SDLLRR DQA +AK +G Sbjct 61 AAEAFARSLHGLLHQQVEIDHEMLSRTVSIGVAAGAPGDETTSDLLRRVDQATRSAKSSG 120 Query 337 GDSVAIFTADMSVSGELRNDIELHLRRGIE--SDALRLVYLPEVDLRTGDIVGTEALVRW 394 G++VA F +MS + +RNDIELHL I+ S AL L YLPE D+RTG ++GTEAL+RW Sbjct 121 GNNVATFRPEMSTTDTIRNDIELHLEGMIDGASGALVLHYLPEFDMRTGAVLGTEALLRW 180 Query 395 QHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQ 454 QHPT GLL P FI V ESINL +L R V+ AC +F WQS G+G A+LRINVS Q Sbjct 181 QHPTLGLLMPDSFIQVVESINLGAKLGRLVMHSACAQFGLWQSRGVGKGAVLRINVSPVQ 240 Query 455 LVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFG 514 LVT G VD VA T+ + LD S++CLEITE+VVVQD+ R TL LK++GV IAIDDFG Sbjct 241 LVTAGIVDTVAATLDEFRLDPSTICLEITESVVVQDIDATRQTLFGLKDIGVQIAIDDFG 300 Query 515 TGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEA 574 TGYS ++ L++LP+D+LKIDK FV + TN DL IVR + LA+ F L VVAEGVET A Sbjct 301 TGYSVLTYLKSLPVDSLKIDKGFVHSVDTNAGDLAIVRSTLALADAFGLGVVAEGVETVA 360 Query 575 AARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPAL 622 AA+ LL C+RAQGFL SRP+ AM +L A+R+ P T PA+ Sbjct 361 AAQTLLSLGCHRAQGFLLSRPLDSAAMESLL-AQRVVPMNFSETGPAV 407 >gi|336461376|gb|EGO40247.1| diguanylate cyclase (GGDEF) domain-containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=415 Score = 423 bits (1088), Expect = 4e-116, Method: Compositional matrix adjust. Identities = 229/412 (56%), Positives = 282/412 (69%), Gaps = 4/412 (0%) Query 9 QLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWP 68 L+ +VT+VA LM A+T+ VS+ VLA LVEQ VD SFL H+D VAEWP Sbjct 4 SLDLVVTSVATALMEATASTARSVSETVLAQLVEQFDVDASFLHHHDAAGPVP--VAEWP 61 Query 69 PRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA 128 R + P + + D + V A CE + P+V P+ +R ++ + S A Sbjct 62 RRTDAAGP--MAALRSEDVESVLAQCERQRRPVVSSPDRVDGWLRRWLQRDKAAGAPSVA 119 Query 129 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDD 188 A PLVSG+ TTG+LGF+KFG R+W E+N L +A LFAQ+QAR+AAE RLRYLA+HDD Sbjct 120 AAPLVSGDATTGVLGFVKFGARRWKPEEINTLEAVAALFAQLQARIAAEERLRYLAEHDD 179 Query 189 LTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIG 248 LTG++NRRAL+ HL +RLA G PGPVA +LDLDRLK INDYLGH AGD FI VFAQRI Sbjct 180 LTGVYNRRALVAHLTERLAAGNPGPVAVFYLDLDRLKPINDYLGHTAGDWFIRVFAQRIE 239 Query 249 DALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGV 308 + +S+IARLGGDEFV+IP PM+++AA+ A RL L D + IGG V++RTVSIG+ Sbjct 240 ECAGEQSMIARLGGDEFVVIPHQPMASEAAEAFARRLSTLLCDRLTIGGHVISRTVSIGL 299 Query 309 ASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESD 368 A GTPG +DLLRRAD+A L AK AGG+ A+ T DMS+ RNDIELHL+ IES+ Sbjct 300 AVGTPGADNCTDLLRRADEAVLTAKRAGGNQTAVSTDDMSLKRAFRNDIELHLQGDIESE 359 Query 369 ALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGEL 420 L L YLPEVDL TG +VG EALVRW+HP GLL P FI VAES NL EL Sbjct 360 GLLLHYLPEVDLWTGAVVGAEALVRWRHPIWGLLLPDSFIGVAESTNLGAEL 411 >gi|41407444|ref|NP_960280.1| hypothetical protein MAP1346c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395796|gb|AAS03663.1| hypothetical protein MAP_1346c [Mycobacterium avium subsp. paratuberculosis K-10] Length=320 Score = 352 bits (902), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 185/321 (58%), Positives = 228/321 (72%), Gaps = 3/321 (0%) Query 304 VSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRR 363 +SIGVA+G PG T SDLLRR DQA +AK +GG++VA F +MS + +RNDIELHL Sbjct 1 MSIGVAAGAPGDETTSDLLRRVDQATRSAKSSGGNNVATFRPEMSTTDTIRNDIELHLEG 60 Query 364 GIE--SDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELD 421 I+ S AL L YLPE D+RTG ++GTEAL+RWQHPT GLL P FI V ESINL +L Sbjct 61 MIDGASGALVLHYLPEFDMRTGAVLGTEALLRWQHPTLGLLMPDSFIQVVESINLGAKLG 120 Query 422 RWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLE 481 R V+ AC +F WQS G+G A+LRINVS QLVT G VD VA T+ + LD S++CLE Sbjct 121 RLVMHSACAQFGLWQSRGVGKGAVLRINVSPVQLVTAGIVDTVAATLDEFRLDPSTICLE 180 Query 482 ITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQL 541 ITE+VVVQD+ R TL LK++GV IAIDDFGTGYS ++ L++LP+D+LKIDK FV + Sbjct 181 ITESVVVQDIDATRQTLFGLKDIGVQIAIDDFGTGYSVLTYLKSLPVDSLKIDKGFVHSV 240 Query 542 GTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAM 601 TN DL IVR + LA+ F L VVAEGVET AAA+ LL C+RAQGFL SRP+ AM Sbjct 241 DTNAGDLAIVRSTLALADAFGLGVVAEGVETVAAAQTLLSLGCHRAQGFLLSRPLDSAAM 300 Query 602 RHMLSARRLPPTCIPATDPAL 622 +L A+R+ P T PA+ Sbjct 301 ESLL-AQRVVPMNFSETGPAV 320 >gi|74317474|ref|YP_315214.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Thiobacillus denitrificans ATCC 25259] gi|74056969|gb|AAZ97409.1| Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) [Thiobacillus denitrificans ATCC 25259] Length=1212 Score = 337 bits (864), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 187/435 (43%), Positives = 263/435 (61%), Gaps = 3/435 (0%) Query 167 FAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPG--QPGPVAALFLDLDRL 224 F + R AEA++++LA HD LTGL NR +L LDQ LA + +A +FLDLDR Sbjct 767 FTDITERKLAEAQIKHLAYHDPLTGLSNRFSLQTQLDQTLALARREQRTLAVVFLDLDRF 826 Query 225 KAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAER 284 K+IND LGHA GDQ + A+R+ D + ++ARLGGDEFV++ A A +A++ Sbjct 827 KSINDSLGHALGDQLLVEVARRLRDNVRDSDIVARLGGDEFVVVLTEVGDAAGAARVADK 886 Query 285 LRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFT 344 L L IGG L T SIG++ L++ AD A AK G D+V FT Sbjct 887 LLGALVPRYRIGGHALHTTASIGISLYPHDGDDADALMKNADTAMYHAKSQGRDNVQFFT 946 Query 345 ADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAP 404 +M+ S R + LR +E+ L Y P+++ +G +V EALVRWQHP GL++P Sbjct 947 PEMNQSVLKRLQFDHDLRVAVEAGQFELHYQPQINSTSGRVVKVEALVRWQHPREGLVSP 1006 Query 405 GCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFV 464 FIP+AE L L WVL AC + W+ AG+ D + +N+SA QL + + V Sbjct 1007 AEFIPIAEETGLILPLGEWVLNEACRQLRLWRDAGIT-DLTVAVNLSAHQLHSPALIPMV 1065 Query 465 ADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQ 524 A T+G HGL+ + +CLEITE+V ++D + A L L+++G+H++IDDFGTGYS++S L+ Sbjct 1066 ARTLGNHGLEGADLCLEITESVAMRDTTASIAQLQALRDLGIHLSIDDFGTGYSSLSYLK 1125 Query 525 TLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRC 584 LPIDTLK+D++FV ++ N SD+ I + LA L+VVAEG+ETE R+L RC Sbjct 1126 LLPIDTLKLDQSFVCEIEFNPSDVAICAATIALAHSLGLEVVAEGIETETQRRLLASHRC 1185 Query 585 YRAQGFLFSRPVPGE 599 QG+LFS P+P E Sbjct 1186 DFMQGYLFSAPLPAE 1200 >gi|334341203|ref|YP_004546183.1| diguanylate cyclase [Desulfotomaculum ruminis DSM 2154] gi|334092557|gb|AEG60897.1| diguanylate cyclase [Desulfotomaculum ruminis DSM 2154] Length=1143 Score = 330 bits (845), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 195/517 (38%), Positives = 281/517 (55%), Gaps = 20/517 (3%) Query 124 VTSAAAVPLVSGEITTGL--LGFIKFGDRKWHEAE---LNALMTIAT-------LFAQVQ 171 + S AVPL SG+ T G+ LGF++ +R+ ++ + LN +A+ LF Q Sbjct 629 IHSTLAVPLKSGQETIGIIGLGFVQ-NNRQLNDEDVTLLNGFAQLASIALENARLFKTAQ 687 Query 172 A----RVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGP--VAALFLDLDRLK 225 R + +R+ A HD LT L NR Q L+ L+ +A FLDLD K Sbjct 688 QELSERTKVQELMRHQAHHDHLTDLPNRILFNQQLNHILSQADKNKEMLAVFFLDLDYFK 747 Query 226 AINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERL 285 +ND LGH GDQ + AQR+ L E +IAR+GGDEF +I + + + A +A+++ Sbjct 748 VVNDTLGHDMGDQLLKGIAQRLSSVLYKEDIIARIGGDEFAIIVNNISARETAAVVAQKI 807 Query 286 RDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTA 345 D LK +G T SIG+A T LL+ AD A AK G ++ + Sbjct 808 IDSLKSPWILGSHEFHITTSIGIALYPADGQTVEILLKNADMAMYQAKDLGKNNYQFYEP 867 Query 346 DMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPG 405 +M R +E +RRG+E + Y P +DL TG IVG EAL+RW HP +GL++P Sbjct 868 NMKDRISQRLALEHSIRRGLEQGEFVIYYQPLLDLSTGKIVGIEALIRWNHPRKGLISPA 927 Query 406 CFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVA 465 FIPVAE L L W+LR AC WQ G + +N+SA Q V VA Sbjct 928 EFIPVAEETGLIIPLGEWILRSACKRNKVWQDNGYP-PMRMAVNLSARQFQQQKLVKKVA 986 Query 466 DTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQT 525 + + GLD + LEITE++ ++D+ L L+++G+ IAIDDFGTGYS++S L+ Sbjct 987 RILEETGLDPRWLELEITESIAMKDVEFTSKMLFELQKMGITIAIDDFGTGYSSLSYLKR 1046 Query 526 LPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCY 585 LPID LKID++F+R + ++ D IV+ I+ LA ++ V AEGVET+ L Q C Sbjct 1047 LPIDILKIDRSFIRDIISDPDDASIVKTIIILAHNLKMKVTAEGVETQEQLNYLRQQGCD 1106 Query 586 RAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPAL 622 QG+LFS+P+PGE + +LS+ L P+++ L Sbjct 1107 EIQGYLFSKPLPGEEIEALLSSSSLYHKSFPSSNQNL 1143 >gi|254503359|ref|ZP_05115510.1| hypothetical protein SADFL11_3398 [Labrenzia alexandrii DFL-11] gi|222439430|gb|EEE46109.1| hypothetical protein SADFL11_3398 [Labrenzia alexandrii DFL-11] Length=777 Score = 323 bits (829), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 202/523 (39%), Positives = 277/523 (53%), Gaps = 16/523 (3%) Query 102 VFRPEPA-------TEDYQRLIEEARGVPVTSAAAVPLVSGE-ITTGLLGFIKFGDRKWH 153 VFR E +E + ++ R + S +VP SG G F R Sbjct 253 VFRKEAVFVEDIFDSELWAEYVDLVREFNLKSCWSVPFFSGSGKVLGTFAFYWTDVRAPS 312 Query 154 EAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRL-APGQPG 212 E E + A L + R AE R+RYLADHD LTGL NRR + L+ ++ A Q G Sbjct 313 EREEKIVREAAHLASIAVERDRAEKRIRYLADHDPLTGLPNRRKFKRKLEAKIEASRQTG 372 Query 213 -PVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRI--GDALVGESLIARLGGDEFVLIP 269 PVA +F+D+D K IND GHA GD + A RI + E++ R GGDEFVL Sbjct 373 EPVAVVFVDMDNFKFINDSYGHAVGDDVLSTVADRILGSHNITFETI--RFGGDEFVLFV 430 Query 270 ASPMSADAA-QPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQA 328 P + + + R+R ++ + + L T SIG A T ++L+ ADQA Sbjct 431 DGPTAHKSELKDYLARMRAEILKTIELDTLTLHVTCSIGTAVFPLDGDTADEVLKNADQA 490 Query 329 ALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGT 388 AK+ G D+ IF + + +G R + LRRGI+++ L L Y P++DL +G IVG Sbjct 491 MFEAKNLGRDNFFIFDRETAPAGVNRLKLVEELRRGIDNNELFLEYQPQIDLMSGRIVGA 550 Query 389 EALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRI 448 EALVRW HP RG L PG FI +AE L RWVL AC + WQ AGL H + + Sbjct 551 EALVRWTHPERGRLMPGEFIEIAEQTGAIISLGRWVLNEACRQNKAWQDAGLPH-ITIAV 609 Query 449 NVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHI 508 NVSA Q + V + GLDA + LE TE++V+Q++ A A + + +G+H+ Sbjct 610 NVSANQFRDKALLSDVFSALDTSGLDARYLELEFTESLVIQNVEQAVALMEDFRRIGIHL 669 Query 509 AIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAE 568 AIDDFGTGYS++ L+ P++ LKID++F+R L SD IVR I++L L+VVAE Sbjct 670 AIDDFGTGYSSLVALKNFPLNRLKIDQSFIRDLEYKESDRAIVRAIISLGRELGLNVVAE 729 Query 569 GVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLP 611 GVET LL RC QG+ F RP+ + +L R P Sbjct 730 GVETAKQQAFLLSCRCETTQGYHFGRPMAADKFSKLLGMTRTP 772 >gi|158338665|ref|YP_001519842.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Acaryochloris marina MBIC11017] gi|158308906|gb|ABW30523.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor, putative [Acaryochloris marina MBIC11017] Length=880 Score = 317 bits (812), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 179/466 (39%), Positives = 260/466 (56%), Gaps = 6/466 (1%) Query 158 NALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQ--RLAPGQPGPV- 214 N IA V A + A+L + A HD++T L NR ++ L R+A Q + Sbjct 414 NQAFRIAGSQTDVTAYYSTRAQLEFKAQHDEMTQLPNRVLFMERLTHAFRMAKHQQSRLF 473 Query 215 AALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMS 274 A LFLDLDR K IND LGH GDQ + ++R+ L + IAR GGDEF ++ + Sbjct 474 AVLFLDLDRFKIINDSLGHRVGDQLLIEVSKRLQQCLRKQDTIARFGGDEFAILLDTVED 533 Query 275 ADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKH 334 AD A +A+R+ LK +++ + + SIG+ +P P +LL+ +D A AK Sbjct 534 ADEAIHVAQRILQALKAKISLEEHEVYTSASIGITVSSPDYQAPEELLQDSDTAMYRAKK 593 Query 335 AGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRW 394 G + +F++ M + +E L+R I ++ L LVY P VDL T +IVG EAL+RW Sbjct 594 QGKNCFEVFSSGMRAQVNSQLQLETDLQRAISNNELHLVYQPIVDLNTENIVGFEALLRW 653 Query 395 QHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDAL-LRINVSAG 453 HP RGL+ P FIPVAE L +D WVL AC + + W + G L + +N+SA Sbjct 654 NHPERGLVPPSEFIPVAEDAGLMVSIDWWVLTEACQQMAHWLNIYPGSTELTINVNISAH 713 Query 454 QLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDF 513 Q + F + V I + G+ + LEITE V++ + L LK++G+H+AIDDF Sbjct 714 QFLQSTFCEKVNAIIQETGMKPHHLKLEITEGVILSNAPNISEQLNNLKKLGIHLAIDDF 773 Query 514 GTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETE 573 GTGYS++S L P+D LK+D +FV ++ + L IVR I+ L + + VVAEGVET+ Sbjct 774 GTGYSSLSYLYAFPLDVLKVDYSFVSRMDQDNG-LAIVRTIVNLGQNLNMKVVAEGVETK 832 Query 574 AAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPT-CIPAT 618 L + C AQG+LFSRP+ E++ +L+ + LP IP T Sbjct 833 IQQEYLQEMGCEFAQGYLFSRPLKKESVESILTNKNLPHIPAIPVT 878 >gi|206601940|gb|EDZ38422.1| Diguanylate cyclase/phosphodiesterase [Leptospirillum sp. Group II '5-way CG'] Length=702 Score = 316 bits (809), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 178/446 (40%), Positives = 253/446 (57%), Gaps = 7/446 (1%) Query 175 AAEARLRYLADHDDLTGLHNRRALLQHLDQ--RLAPGQPGPVAALFLDLDRLKAINDYLG 232 AA +L YLA HD LT L NR L +DQ R A G G + FLD+DR K IND LG Sbjct 255 AANEKLHYLALHDGLTRLPNRTLLEDRVDQAIRHARGVDGAFSVFFLDVDRFKPINDSLG 314 Query 233 HAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDH 292 H+ GD+ + A+R+ + E +AR+GGDEFV++ +A ++RD + ++ Sbjct 315 HSTGDKVLQQMARRLSGTVGPEDTVARIGGDEFVIVFPEQKDPGKVHEIARKIRDCVAEN 374 Query 293 VAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGE 352 + + G+ L+ T SIG++ T LL AD A AK G + ++ +++ S Sbjct 375 MEVDGQSLSVTTSIGISLFPHDGTTFRTLLASADSAMYYAKSKGSGQIQFYSGELNDSAA 434 Query 353 LRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAE 412 LR ++E LRRGIE + L Y P+V L TG++ EALVRW HP +G+L P FIP AE Sbjct 435 LRIEMENDLRRGIEKEEFVLYYQPKVTLATGEVESVEALVRWNHPEKGILPPHYFIPRAE 494 Query 413 SINLAGELDRWVLRRACNEFSEWQSAGLGHDALLR--INVSAGQLVTGGFVDFVADTIGQ 470 L L RW++ RAC E WQ AG LR +N+SA Q + + + D + Sbjct 495 ETGLIIPLGRWIMDRACREAVIWQQAGFSR---LRVAVNLSALQFINQDLMKEILDALES 551 Query 471 HGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDT 530 GL + LEITE+++++D A TL+ +++ GVH+AIDDFGTGYS+ S L+ P+D Sbjct 552 SGLPPECLELEITESLLMEDPEGAMRTLSGIRQKGVHVAIDDFGTGYSSFSYLKKFPLDR 611 Query 531 LKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGF 590 LKID++F+ + N +D IVR I+TL L V+AEGVE++A +L C QGF Sbjct 612 LKIDRSFITDICDNPNDAAIVRTIITLGHNLNLKVIAEGVESQAQLEMLKAMECDAYQGF 671 Query 591 LFSRPVPGEAMRHMLSARRLPPTCIP 616 SRP+P + L RL T +P Sbjct 672 FNSRPLPPGELAERLKEMRLLKTPLP 697 >gi|124516000|gb|EAY57509.1| Diguanylate cyclase/phosphodiesterase [Leptospirillum rubarum] Length=702 Score = 313 bits (803), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 180/449 (41%), Positives = 250/449 (56%), Gaps = 7/449 (1%) Query 175 AAEARLRYLADHDDLTGLHNRRALLQHLDQ--RLAPGQPGPVAALFLDLDRLKAINDYLG 232 AA +L YLA HD LT L NR L +DQ R A G + FLD+DR K IND LG Sbjct 255 AANEKLHYLALHDGLTRLPNRTLLEDRVDQAIRHARSGDGTFSVFFLDVDRFKPINDSLG 314 Query 233 HAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDH 292 H+ GD+ + A R+ + E +AR+GGDEFV++ +A R+RD + + Sbjct 315 HSTGDKVLQQMASRLSATVGPEDTVARIGGDEFVIVFPEKKDPGKVHEIARRIRDCVAES 374 Query 293 VAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGE 352 + + G+ L+ T SIG++ T LL AD A AK G + ++ +M+ S Sbjct 375 MEVDGQSLSVTTSIGISLFPHDGTTFRTLLASADSAMYYAKSKGPGQIQFYSGEMNDSAA 434 Query 353 LRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAE 412 LR ++E LRRGIE + L Y P+V L TG++ EALVRW HP +G+L P FIP AE Sbjct 435 LRIEMENDLRRGIEKEEFVLYYQPKVSLATGEVESVEALVRWNHPEKGILPPHYFIPRAE 494 Query 413 SINLAGELDRWVLRRACNEFSEWQSAGLGHDALLR--INVSAGQLVTGGFVDFVADTIGQ 470 L L RW++ RAC E W AG LR +N+SA Q + V + + + Sbjct 495 ETGLIIPLGRWIMDRACREAVIWHQAGFPR---LRVAVNLSALQFINQDLVREILTALER 551 Query 471 HGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDT 530 GL + LEITE++++QD A TL+ ++E GVH+AIDDFGTGYS+ S L+ P+D Sbjct 552 SGLSPECLELEITESLLMQDPDAAMRTLSGIREKGVHVAIDDFGTGYSSFSYLKKFPLDR 611 Query 531 LKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGF 590 LKID++F+ + N +D IVR I+TL L V+AEGVE++A +L C QGF Sbjct 612 LKIDRSFITDICDNPNDAAIVRTIITLGHNLNLKVIAEGVESQAQLEMLKTMECDAYQGF 671 Query 591 LFSRPVPGEAMRHMLSARRLPPTCIPATD 619 SRP+P + L R+ T +P D Sbjct 672 YNSRPLPPGELAERLKEMRILKTPLPDED 700 >gi|134299209|ref|YP_001112705.1| PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase [Desulfotomaculum reducens MI-1] gi|134051909|gb|ABO49880.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) [Desulfotomaculum reducens MI-1] Length=947 Score = 313 bits (803), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 179/493 (37%), Positives = 265/493 (54%), Gaps = 18/493 (3%) Query 122 VPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMT-----------IATLFAQV 170 + + A+PL S G+LG I + E+ +L+T A L+ Sbjct 439 IKIHGGIALPLKSEGKINGILGIIYIEKNQNLESNNLSLLTGFAQLASIALDNANLYQAA 498 Query 171 QARVAAEAR----LRYLADHDDLTGLHNRRALLQHLDQRL--APGQPGPVAALFLDLDRL 224 Q +A R LRYLA HD LT L NR L L A +A +FLDLD Sbjct 499 QQELAERKRIEEILRYLAYHDSLTELPNRTLFNDRLSMALNQAHRNKNKLAVMFLDLDHF 558 Query 225 KAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAER 284 K +ND LGH GDQ + AQR L IAR+GGDEF ++ + A+ A +A++ Sbjct 559 KKVNDTLGHDIGDQLLKGIAQRFSKLLRKGDTIARIGGDEFTILLHNITRAENASIVADK 618 Query 285 LRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFT 344 + D L + IG T SIG+A LL+ AD A AK G ++ +T Sbjct 619 IIDTLANPWIIGNHEFHITTSIGIALYPDDGTDAESLLKNADAAMYQAKEMGRNNYQFYT 678 Query 345 ADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAP 404 M+ R ++E +LRR ++ + Y P+V++ TG IVG EAL+RWQHP RG+++P Sbjct 679 PTMNAQTLRRFELENNLRRALDRKEFVIYYQPQVEIHTGKIVGVEALIRWQHPQRGMISP 738 Query 405 GCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFV 464 FIP+AE L + W+LRRAC + WQ G + +N+SA Q + ++ Sbjct 739 AEFIPMAEETGLIIPIGEWILRRACAQNKAWQDRGFS-PMRVTVNLSARQFLQPHLPQYI 797 Query 465 ADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQ 524 ++ + GL + LEITE++ ++D+ TL L+++G+ +AIDDFGTGYS+++ L+ Sbjct 798 SNVLEDTGLGPQWLELEITESLAMKDVAFTEKTLIELRKMGITLAIDDFGTGYSSLNYLK 857 Query 525 TLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRC 584 LPID LKID++F+ L T + D+ I+ I+TL ++ VVAEGVET+ L Q+C Sbjct 858 RLPIDILKIDRSFIHDLNTESDDVAIISAIITLGHNLKMKVVAEGVETKEQLMFLRQQQC 917 Query 585 YRAQGFLFSRPVP 597 QG+LF++P+P Sbjct 918 DLMQGYLFTKPLP 930 >gi|119486033|ref|ZP_01620095.1| Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation [Lyngbya sp. PCC 8106] gi|119456808|gb|EAW37936.1| Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation [Lyngbya sp. PCC 8106] Length=601 Score = 312 bits (800), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 201/594 (34%), Positives = 304/594 (52%), Gaps = 41/594 (6%) Query 35 RVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRL-----NIPDPDPLRLIYFADADP 89 R+L+ ++ G +V R + A V PP L +PD D + F DP Sbjct 24 RLLSTMLSDQGYEV---RQAINGKMALTAVQTCPPSLILLDIMMPDIDGYEVCSFLKNDP 80 Query 90 VFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAV--PLVSGEITTGLLGFIKF 147 + A P++F A +D ++++ + V + P EI + + Sbjct 81 -----QTADIPIIFLS--ALDD---VLDKVKAFKVGGVDYITKPFEFEEILARVKNQLAL 130 Query 148 GDRKWHEAELNALMTIATLFAQVQARV--------AAEARLRYLADHDDLTGLHNRRALL 199 D K ++TL +Q++ RV A A+L +A HD LTGL NRR L+ Sbjct 131 KDAK---------SKLSTLNSQLEKRVEQRKKQLEVANAKLLEMALHDPLTGLPNRRFLM 181 Query 200 QHLDQRLAPGQP---GPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESL 256 + L+Q L + A LFLD DR K +ND LGH GD+ + ++R+ L + + Sbjct 182 EQLEQSLNRAKQDSQSQFAVLFLDCDRFKVVNDSLGHLVGDELLIALSRRLETLLNPDDI 241 Query 257 IARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQH 316 +ARLGGDEF+++ S + +A + + L + G + SIG+A P Sbjct 242 LARLGGDEFIILLKSIHHSQQVTQIANSILEALSQPFQLEGYEVFINTSIGIALWHPNYE 301 Query 317 TPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLP 376 P LLR AD A AK G IF + M V+ ++E L + I+ L + Y P Sbjct 302 NPEHLLRDADNAVYKAKALGRGRYHIFDSTMHVAAINTLELETELHKAIKEQELVVYYQP 361 Query 377 EVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQ 436 V L TG IVG EALVRWQHPTRGL++P FIP+AE I L L +WVL ++C + W+ Sbjct 362 IVVLNTGQIVGFEALVRWQHPTRGLISPHSFIPIAEEIGLIIPLGQWVLHQSCQQLQTWK 421 Query 437 SAGLGHDALL-RINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTAR 495 L D+ +N+SA QL + V I ++ + LEITE+ ++++ A Sbjct 422 KQNLVDDSFFVSVNLSARQLTQLNLNEQVDQIIHDTQINPQCLKLEITESSLMENPQIAI 481 Query 496 ATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIM 555 L + K+ G+ + IDDFGTGYS++S L P+DTLKID++FV+Q+ N+ L +V I+ Sbjct 482 EILKKFKQRGIQLGIDDFGTGYSSLSYLHYFPLDTLKIDQSFVKQIDENSKHLGLVPIII 541 Query 556 TLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARR 609 +A+ +++V+AEG+ET R LL C QG+LFSRPV E ++S+ + Sbjct 542 NIAKILEMNVIAEGIETPTQLRQLLSLNCKLGQGYLFSRPVNAEEAIRLVSSNQ 595 >gi|296132513|ref|YP_003639760.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Thermincola sp. JR] gi|296031091|gb|ADG81859.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Thermincola potens JR] Length=706 Score = 312 bits (799), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 172/434 (40%), Positives = 247/434 (57%), Gaps = 4/434 (0%) Query 166 LFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGP--VAALFLDLDR 223 F + R AE +++ A HD LTGL NR L Q LA + +A +FLDLDR Sbjct 263 FFYDITERKMAEEAIKHQAYHDPLTGLPNRILFKDRLTQTLAQAKRSKQMLALMFLDLDR 322 Query 224 LKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAE 283 K IND LGHA GDQF+ ++R+ + +ARLGGDEF L+ + A +A+ Sbjct 323 FKNINDTLGHATGDQFLQGISKRLTGCIRSGDTVARLGGDEFTLLLPQINHVEDAIKVAQ 382 Query 284 RLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIF 343 ++ D K +GG T SIG+A L++ AD A AK G ++ ++ Sbjct 383 KIIDTFKKPWILGGHEFYITTSIGIALYPNDGEDAETLMKHADTAMYRAKERG-NNYQLY 441 Query 344 TADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLA 403 + M+ R ++E LR+ +E + + Y P+++ TG+I+G EALVRW+HP RG++ Sbjct 442 SPSMNEKAINRLEMEGALRKALEREEFTVYYQPQINTDTGEIIGMEALVRWRHPERGIIP 501 Query 404 PGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDF 463 P FI +AE L L WVLR AC + EWQ AG + +N+SA Q D Sbjct 502 PADFIALAEETGLILPLGEWVLRTACRQNKEWQMAGYP-PLRVTVNLSASQFQQQDLADR 560 Query 464 VADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLL 523 V+ + + GLD + LEITE++ ++D+ TL +L+++G+ IAIDDFGTGYS++S L Sbjct 561 VSRILKETGLDPQWLELEITESIAMKDVAFTIKTLRQLRDMGIKIAIDDFGTGYSSLSYL 620 Query 524 QTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQR 583 + +P TLKIDK+FVR + NT D I I+ +A+ +L V+AEGVETE L Q+ Sbjct 621 KQIPSHTLKIDKSFVRDIAKNTEDGSIASAIIAMAQNLKLKVIAEGVETEEQLAFLKKQK 680 Query 584 CYRAQGFLFSRPVP 597 C QGFLF +PVP Sbjct 681 CDEIQGFLFGKPVP 694 >gi|337746728|ref|YP_004640890.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Paenibacillus mucilaginosus KNP414] gi|336297917|gb|AEI41020.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Paenibacillus mucilaginosus KNP414] Length=754 Score = 311 bits (796), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 172/439 (40%), Positives = 243/439 (56%), Gaps = 10/439 (2%) Query 167 FAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQ----PGPVAALFLDLD 222 F + R AE R YLA+HDDLT L NRR L + Q P +A ++LDLD Sbjct 302 FRNITDRYEAEERYNYLANHDDLTDLPNRRYYKMKLHSMIEQAQMGLHPYQIAVIYLDLD 361 Query 223 RLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLA 282 R K +ND LGH GD + + R+ L LIAR+GGDEF+ + SA+ Sbjct 362 RFKLVNDTLGHTNGDMLLKLVVDRLKSLLGPGDLIARMGGDEFMFMLPGIQSAEEVTSRV 421 Query 283 ERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAI 342 E + + + G T SIG+A L+ AD A AK G + + Sbjct 422 ENILRLFRQPFNMNGYEFHITASIGIAMYPDDGLDIEMLMIHADTAMYKAKERGKNQYLL 481 Query 343 FTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLL 402 +++DM + +E LRR +E++ L Y P++D+R+G + G EALVRWQHP RG++ Sbjct 482 YSSDMQTRSHEKIRMETSLRRALENNEFVLYYQPQIDIRSGRVKGVEALVRWQHPERGIV 541 Query 403 APGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRI--NVSAGQLVTGGF 460 +P FIP+AE L LD+WVLR AC++ +WQ GL A LRI N+S+ Q Sbjct 542 SPFEFIPLAEETGLIIPLDQWVLRTACHQNKKWQDMGL---APLRIAVNLSSQQFAKDSL 598 Query 461 VDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAI 520 VD V + + + GLD + LEITE + + HT TL +L +GV I+IDDFGTGYS++ Sbjct 599 VDIVQEILQESGLDPQYLELEITETMTMDVEHTI-PTLEKLHALGVQISIDDFGTGYSSL 657 Query 521 SLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILL 580 + L+ ID LKID++FVR + + D IV I+ +A G L+V+AEGVE + L Sbjct 658 NYLKKFSIDRLKIDQSFVRDIMFDAHDSDIVGTIIAMAHGMGLEVIAEGVEDAGQLQFLR 717 Query 581 DQRCYRAQGFLFSRPVPGE 599 +Q C QG+ +S+P+P E Sbjct 718 NQNCNEVQGYYYSKPIPAE 736 >gi|197118094|ref|YP_002138521.1| response receiver sensor diguanylate cyclase/phosphodiesterase [Geobacter bemidjiensis Bem] gi|197087454|gb|ACH38725.1| response receiver sensor diguanylate cyclase/phosphodiesterase, GAF domain-containing protein [Geobacter bemidjiensis Bem] Length=869 Score = 309 bits (792), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 176/441 (40%), Positives = 255/441 (58%), Gaps = 3/441 (0%) Query 177 EARLRYLADHDDLTGLHNRRALLQHLDQ--RLAPGQPGPVAALFLDLDRLKAINDYLGHA 234 E R+ YLA +D +T L NR +L+ L Q LA +A +F+DLDR K IND LGH Sbjct 429 EQRVEYLAHYDMVTKLPNRFSLMARLGQALELAKRFSSRLAVIFIDLDRFKNINDSLGHH 488 Query 235 AGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVA 294 GD+ + A R+ D + ++ARLGGDEFV++ S +A +++ L Sbjct 489 IGDRLLFQVAGRLQDTIRSADIVARLGGDEFVVVLPLINSNISAAHAVRKIQQTLSQGYT 548 Query 295 IGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELR 354 + L T SIG++ T +L++ AD A AK AG +S FT +M+++ + R Sbjct 549 VESHELNITPSIGISVYPTDGETVQELMKHADLAMYHAKSAGRNSYQFFTQEMNLTVQAR 608 Query 355 NDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESI 414 +E LR +E D L L Y P++DL++GD+VG EAL+RW+HP RG +AP FIPVAE Sbjct 609 LVLESDLRTALERDELMLHYQPQIDLKSGDVVGVEALLRWRHPVRGAVAPDVFIPVAEDT 668 Query 415 NLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLD 474 L + + L+ AC + + W S GLG + +N+SA Q +AD + G+ Sbjct 669 GLILSIGEFALKSACEQLALWISQGLG-PLRMAVNLSARQFKQSNLPSLLADILAATGVA 727 Query 475 ASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKID 534 A + LEITE+ + D ++A L L+E+GV +AIDDFGTGYS++S L+ P++ LKID Sbjct 728 AHLLELEITESSAMDDPNSAILHLRTLREMGVKLAIDDFGTGYSSLSYLKLFPVNRLKID 787 Query 535 KTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSR 594 ++FVR + T++ D I +TLA +VVAEGVETEA R L Q+C QG+ FS Sbjct 788 RSFVRGIDTDSEDAEIAAATITLAHNLGKEVVAEGVETEAQCRFLKGQQCDILQGYFFSE 847 Query 595 PVPGEAMRHMLSARRLPPTCI 615 P+ + L+A R PPT + Sbjct 848 PLSAAGIASYLAANRRPPTLV 868 >gi|222053961|ref|YP_002536323.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Geobacter sp. FRC-32] gi|221563250|gb|ACM19222.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Geobacter sp. FRC-32] Length=749 Score = 308 bits (790), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 174/445 (40%), Positives = 243/445 (55%), Gaps = 3/445 (0%) Query 163 IATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGP--VAALFLD 220 A L V R E ++R LA +D+LTGL NR L+ L+Q L + V LFLD Sbjct 280 FAFLMEDVTQRKVNEEQIRRLAYYDNLTGLPNRALLMDRLEQMLTKARRDKTRVVLLFLD 339 Query 221 LDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQP 280 LDR K IND +GHA GDQ + A R+ AL +AR+GGDEFV++ P Sbjct 340 LDRFKVINDTMGHAHGDQLLVQVANRLRQALRSSDTLARIGGDEFVVLFTLEGPQLNVSP 399 Query 281 LAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSV 340 LA+ L D + I G + + SIG+A+ + LLR AD A AAK GG Sbjct 400 LAQHLIDSITSVYPISGRDVYASTSIGIATFPDDGGDCNSLLRCADMAMYAAKEGGGKGY 459 Query 341 AIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG 400 ++ +M++ R ++E +LR +E + L + P V+ R G +VG EAL+RW P +G Sbjct 460 HFYSPEMNLKAHARMEMETNLRHALEREEFFLEFQPIVNARDGRLVGAEALLRWSDPEKG 519 Query 401 LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGF 460 L+ P FI VAE L WVLR AC + +W+ AGL + +NVS Q F Sbjct 520 LIMPDMFIQVAEESGFIVPLGEWVLRTACRKMKDWREAGLP-PFRISVNVSGRQFCQANF 578 Query 461 VDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAI 520 D V I + G+D S + LE+TE ++ D+ L +LKE+ + I IDDFG GYS++ Sbjct 579 TDTVCSIIRETGMDPSFLALEMTETSLMVDVEATAKALMQLKELDISIVIDDFGAGYSSL 638 Query 521 SLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILL 580 LQ PID +KID++F+R L ++ +D IV I+ +A +L VVAEGVET L Sbjct 639 GYLQKFPIDRIKIDRSFIRDLSSHANDKAIVEAIIAMAARLKLQVVAEGVETSEQLDFLK 698 Query 581 DQRCYRAQGFLFSRPVPGEAMRHML 605 +Q C+ QGF F RP+ E + +L Sbjct 699 EQGCHEIQGFYFHRPLSEELFKTLL 723 >gi|34496829|ref|NP_901044.1| hypothetical protein CV_1374 [Chromobacterium violaceum ATCC 12472] gi|34102684|gb|AAQ59049.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472] Length=842 Score = 308 bits (790), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 181/444 (41%), Positives = 257/444 (58%), Gaps = 5/444 (1%) Query 166 LFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGP--VAALFLDLDR 223 +F+ + R AE RL +LA+HD LT L NR L+ L + G +A LF+DLDR Sbjct 393 VFSDITQRKQAEERLHFLANHDALTSLPNRTLFLEKLQGAVERAGLGGQRLALLFIDLDR 452 Query 224 LKAINDYLGHAAGDQF-IHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLA 282 K +ND LGH AGDQ IH+ Q L GE+ +ARLGGDEF L+ A Sbjct 453 FKLVNDTLGHYAGDQLLIHIARQLQSRLLPGET-VARLGGDEFTLLLEGVGGEAQVAARA 511 Query 283 ERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAI 342 + + D + + + G+ + + SIG++ LL AD A AK G + Sbjct 512 QAMLDAITELSGVAGQQMFISASIGISMFPLDGRDADTLLVHADTAMYRAKDGGKNGFQF 571 Query 343 FTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLL 402 +T DM+ R +E L R + L L Y P+V L +G ++G EAL+RW+HP GL+ Sbjct 572 YTPDMNARALERLKLEYSLHRALAQQELELWYQPKVALDSGQLIGAEALLRWRHPELGLV 631 Query 403 APGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVD 462 P FIP+AE L ++ WVL AC + W++AGL L +NVS QL G FV Sbjct 632 PPDRFIPIAEESALIAQIGAWVLETACADARRWRNAGLA-PGRLAVNVSGRQLKHGDFVA 690 Query 463 FVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISL 522 + + +HGLD+ ++ LEITE+VV++D TL RL+++G++++IDDFGTGYS++S Sbjct 691 ELEQALARHGLDSDALELEITESVVMEDAGGMVDTLFRLQKLGMYLSIDDFGTGYSSLSY 750 Query 523 LQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQ 582 L+ LP+ LKID++F+ L + D I R I+++A LDVVAEGVE EA R LL+Q Sbjct 751 LKRLPVRGLKIDRSFIDDLHCDGDDAAITRAIISIARSLGLDVVAEGVEEEAQRRFLLEQ 810 Query 583 RCYRAQGFLFSRPVPGEAMRHMLS 606 C AQG+LFS+P+P +A +LS Sbjct 811 GCNCAQGYLFSKPLPRDAYEALLS 834 >gi|56477067|ref|YP_158656.1| putative sensory box/GGDEF family protein [Aromatoleum aromaticum EbN1] gi|56313110|emb|CAI07755.1| putative sensory box/GGDEF family protein [Aromatoleum aromaticum EbN1] Length=698 Score = 307 bits (786), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 183/436 (42%), Positives = 244/436 (56%), Gaps = 1/436 (0%) Query 170 VQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAIND 229 V AR AE RL + A HD LTGL NR L + +A + A +FLDLDR K +ND Sbjct 257 VTARTHAEKRLIHQASHDALTGLPNRNLLNDRITHAIARSRGRLTAVMFLDLDRFKLVND 316 Query 230 YLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQL 289 GHA GD I A R+ L +ARLGGDEFV++ S + A LA +LRD+L Sbjct 317 SYGHAVGDALIREVANRVSACLRAGDTVARLGGDEFVVLLEDLASIEDAARLAAKLRDRL 376 Query 290 KDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSV 349 + V IG L + SIGVA P LL+ AD A AK G ++ + +M Sbjct 377 SESVRIGSLELPLSASIGVALAPRDGRDPEMLLKNADIAMYRAKERGRNNYCFYGPEMDH 436 Query 350 SGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIP 409 R +E LRR + L Y P+VDL TG + G EALVRW+HP R LL PG FI Sbjct 437 HARRRLTVESELRRALAGGELEAHYQPQVDLATGALTGAEALVRWRHPERCLLLPGEFIA 496 Query 410 VAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIG 469 VAE L L VLR AC + + W+ AG D + +N+S Q V+ V D + Sbjct 497 VAEETGLIVPLGEQVLRAACRQSTRWREAGR-PDLKVAVNLSGHQFRQHDLVEQVCDILA 555 Query 470 QHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPID 529 + G A+ + LEITE+V + D + ATLA L+ G+ +AIDDFGTGYS++S L+ PID Sbjct 556 ETGAHAAQLELEITESVAMADADGSVATLAGLRRQGIALAIDDFGTGYSSLSYLKRFPID 615 Query 530 TLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQG 589 TLKID++F++ + + D IV+ I+ +A +L ++AEGVET A L+ Q C QG Sbjct 616 TLKIDRSFIQGIPADGDDTAIVQAIIAMARSLRLSLLAEGVETPAQREFLVAQGCRSGQG 675 Query 590 FLFSRPVPGEAMRHML 605 FLF R +P E H++ Sbjct 676 FLFGRAMPAEDFHHII 691 >gi|218438075|ref|YP_002376404.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Cyanothece sp. PCC 7424] gi|218170803|gb|ACK69536.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Cyanothece sp. PCC 7424] Length=812 Score = 307 bits (786), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 171/442 (39%), Positives = 258/442 (59%), Gaps = 5/442 (1%) Query 170 VQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQ---RLAPGQPGPVAALFLDLDRLKA 226 + R AE RLR+ HD LTGL NR L+Q L+Q R A LF+DLDR K Sbjct 369 ITQRKLAEKRLRHEVLHDSLTGLPNRTLLIQRLEQVRHRAKRKANYCFALLFIDLDRFKN 428 Query 227 INDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLR 286 IND LGH GD+ + A R+ + + +ARLGGDEF+++ + ER+ Sbjct 429 INDNLGHPIGDRVLITIASRLQECVRSLDTVARLGGDEFIILLDELEEEKEIFKIIERIE 488 Query 287 DQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTAD 346 QL + I G+ L+ T SIG+A + SDLLR AD A K+ G AI+ ++ Sbjct 489 KQLTTPMVIEGQTLSLTASIGIAFNDTN-LSNSDLLRNADLAMYRVKNEGKAGYAIYQSE 547 Query 347 MSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGC 406 M + ++E HL+ IE L Y P + L+T ++G EAL+RWQHP RGL++P Sbjct 548 MYAQAQALWELENHLKLAIERQEFLLYYQPILSLKTLTVIGFEALIRWQHPQRGLISPVH 607 Query 407 FIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDAL-LRINVSAGQLVTGGFVDFVA 465 FIPVAE +L + WVL+++C + S W+ + L + +N+S QL FV + Sbjct 608 FIPVAEETDLIVAIGEWVLQQSCQQLSAWREKYPQANHLTINVNLSNRQLEKDNFVYKLD 667 Query 466 DTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQT 525 + + Q GL A+ + LEITE +++ +L A ATL++LK+ ++I+IDDFGTGYS+++ L Sbjct 668 NVLQQTGLPATQLKLEITETLLMTNLAAAIATLSQLKQRNINISIDDFGTGYSSLNYLCR 727 Query 526 LPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCY 585 LP+ +LKID++FV + ++ +L I++ I++L E ++V+AEG+ET+ L + C Sbjct 728 LPVSSLKIDRSFVANVHEDSKNLQIIQTILSLGEQLMIEVIAEGIETQKHLEQLQELGCQ 787 Query 586 RAQGFLFSRPVPGEAMRHMLSA 607 QG+LFS+PV EA ++ A Sbjct 788 YGQGYLFSKPVNCEAAEQLICA 809 >gi|78222002|ref|YP_383749.1| diguanylate cyclase/phosphodiesterase [Geobacter metallireducens GS-15] gi|78193257|gb|ABB31024.1| diguanylate cyclase/phosphodiesterase [Geobacter metallireducens GS-15] Length=736 Score = 306 bits (785), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 173/450 (39%), Positives = 253/450 (57%), Gaps = 3/450 (0%) Query 163 IATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPG--QPGPVAALFLD 220 ATLF R ++ +++ LA +D LT L NR L L+Q LA G A F+D Sbjct 281 FATLFEDTTERKKSDEQIQRLAYYDTLTALPNRTLFLDRLEQALAGAIRDNGKFALFFID 340 Query 221 LDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQP 280 LD K IND LGHA GD + + +QR+ + + + +ARLGGDEF+++ + A Sbjct 341 LDGFKVINDNLGHAQGDLLLTMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAH 400 Query 281 LAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSV 340 LA+ L +++ IG V+ + SIG++ LLR AD A AAK AG + Sbjct 401 LAQHLLERISPPYEIGSRVVYTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGY 460 Query 341 AIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRG 400 + +M+ R ++E+ LR+ +E D L + P +++ +VG EALVRWQHP +G Sbjct 461 HFHSPEMNRKAHERMELEMSLRQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQG 520 Query 401 LLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGF 460 + PG FIP+AES L L WVLR+AC + EW+ AGL L +N+S Q F Sbjct 521 RVMPGTFIPLAESSGLIIPLGEWVLRKACEKMKEWRDAGL-PPVKLSVNISGRQFEQRNF 579 Query 461 VDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAI 520 V + + + G+DA ++ E+TE +++D + L +LKE+ + I +DDFGTGYS++ Sbjct 580 TALVDEVLKETGVDARALQFELTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSL 639 Query 521 SLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILL 580 + L+ PID +KID++FV + + D IV I+ +A LDVVAEGVET +LL Sbjct 640 AYLKNFPIDHIKIDRSFVMDICDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLL 699 Query 581 DQRCYRAQGFLFSRPVPGEAMRHMLSARRL 610 D C+ QGFLF RP+P E +L RL Sbjct 700 DLGCHEMQGFLFHRPLPEEKFVELLRDVRL 729 Lambda K H 0.321 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1429258453920 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40