BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1357c
Length=307
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608497|ref|NP_215873.1| hypothetical protein Rv1357c [Mycob... 629 2e-178
gi|121637288|ref|YP_977511.1| hypothetical protein BCG_1419c [My... 628 4e-178
gi|340626373|ref|YP_004744825.1| hypothetical protein MCAN_13751... 625 3e-177
gi|308231816|ref|ZP_07413873.2| hypothetical protein TMAG_03504 ... 588 4e-166
gi|289569370|ref|ZP_06449597.1| conserved hypothetical protein [... 541 6e-152
gi|15827938|ref|NP_302201.1| hypothetical protein ML1752 [Mycoba... 386 2e-105
gi|297194219|ref|ZP_06911617.1| sensory box/GGDEF family protein... 239 4e-61
gi|145595796|ref|YP_001160093.1| diguanylate cyclase [Salinispor... 237 2e-60
gi|294812804|ref|ZP_06771447.1| Sensory box/GGDEF family protein... 236 3e-60
gi|302551644|ref|ZP_07303986.1| sensory box/GGDEF family protein... 236 5e-60
gi|328882651|emb|CCA55890.1| putative sensory box or GGDEF famil... 234 1e-59
gi|297199917|ref|ZP_06917314.1| sensory box/GGDEF family protein... 233 3e-59
gi|311896188|dbj|BAJ28596.1| putative signaling protein [Kitasat... 230 2e-58
gi|291439458|ref|ZP_06578848.1| sensory box/GGDEF family protein... 230 3e-58
gi|302560492|ref|ZP_07312834.1| sensory box/GGDEF family protein... 229 5e-58
gi|159039053|ref|YP_001538306.1| diguanylate cyclase/phosphodies... 228 9e-58
gi|297160240|gb|ADI09952.1| sensory box/GGDEF family protein [St... 228 1e-57
gi|345015412|ref|YP_004817766.1| PAS/PAC sensor-containing digua... 227 2e-57
gi|294629517|ref|ZP_06708077.1| developmental regulator MorA [St... 226 5e-57
gi|29831780|ref|NP_826414.1| sensory box/GGDEF family protein [S... 225 5e-57
gi|256380853|ref|YP_003104513.1| PAS/PAC sensor(s)-containing di... 225 7e-57
gi|302545149|ref|ZP_07297491.1| developmental regulator MorA [St... 224 2e-56
gi|330469358|ref|YP_004407101.1| diguanylate cyclase/phosphodies... 223 2e-56
gi|238060306|ref|ZP_04605015.1| diguanylate cyclase/phosphodiest... 223 3e-56
gi|329937967|ref|ZP_08287449.1| putative sensory box/GGDEF famil... 223 3e-56
gi|337765894|emb|CCB74603.1| Sensory box/GGDEF family protein [S... 222 5e-56
gi|302869003|ref|YP_003837640.1| diguanylate cyclase [Micromonos... 222 5e-56
gi|182438510|ref|YP_001826229.1| hypothetical protein SGR_4717 [... 221 1e-55
gi|326779157|ref|ZP_08238422.1| diguanylate cyclase/phosphodiest... 221 1e-55
gi|254387213|ref|ZP_05002479.1| sensory box/GGDEF protein [Strep... 220 3e-55
gi|239987963|ref|ZP_04708627.1| hypothetical protein SrosN1_1169... 218 6e-55
gi|344999882|ref|YP_004802736.1| PAS/PAC sensor-containing digua... 218 9e-55
gi|134103559|ref|YP_001109220.1| diguanylate cyclase/phosphodies... 218 1e-54
gi|331697858|ref|YP_004334097.1| PAS/PAC sensor-containing digua... 217 2e-54
gi|302534564|ref|ZP_07286906.1| sensory box/GGDEF protein [Strep... 216 4e-54
gi|21221267|ref|NP_627046.1| hypothetical protein SCO2817 [Strep... 214 1e-53
gi|320010638|gb|ADW05488.1| diguanylate cyclase/phosphodiesteras... 214 1e-53
gi|290960135|ref|YP_003491317.1| diguanylate cyclase [Streptomyc... 211 1e-52
gi|302865940|ref|YP_003834577.1| diguanylate cyclase [Micromonos... 211 1e-52
gi|315502496|ref|YP_004081383.1| diguanylate cyclase/phosphodies... 211 1e-52
gi|329938501|ref|ZP_08287926.1| sensory box/GGDEF family protein... 209 4e-52
gi|324998105|ref|ZP_08119217.1| diguanylate cyclase/phosphodiest... 209 5e-52
gi|288919235|ref|ZP_06413571.1| diguanylate cyclase/phosphodiest... 207 2e-51
gi|295835411|ref|ZP_06822344.1| sensory box/GGDEF family protein... 206 3e-51
gi|331694322|ref|YP_004330561.1| PAS/PAC sensor-containing digua... 206 4e-51
gi|302523204|ref|ZP_07275546.1| diguanylate cyclase/phosphodiest... 205 9e-51
gi|117165116|emb|CAJ88670.1| conserved hypothetical protein [Str... 203 2e-50
gi|302538187|ref|ZP_07290529.1| conserved hypothetical protein [... 203 2e-50
gi|254383498|ref|ZP_04998849.1| conserved hypothetical protein [... 203 2e-50
gi|290955706|ref|YP_003486888.1| hypothetical protein SCAB_11501... 203 3e-50
>gi|15608497|ref|NP_215873.1| hypothetical protein Rv1357c [Mycobacterium tuberculosis H37Rv]
gi|15840812|ref|NP_335849.1| hypothetical protein MT1400 [Mycobacterium tuberculosis CDC1551]
gi|31792553|ref|NP_855046.1| hypothetical protein Mb1392c [Mycobacterium bovis AF2122/97]
48 more sequence titles
Length=307
Score = 629 bits (1622), Expect = 2e-178, Method: Compositional matrix adjust.
Identities = 307/307 (100%), Positives = 307/307 (100%), Gaps = 0/307 (0%)
Query 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS
Sbjct 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
Query 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
Sbjct 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
Query 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
Sbjct 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
Query 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
Sbjct 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
Query 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
Sbjct 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
Query 301 PVDFFRE 307
PVDFFRE
Sbjct 301 PVDFFRE 307
>gi|121637288|ref|YP_977511.1| hypothetical protein BCG_1419c [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224989762|ref|YP_002644449.1| hypothetical protein JTY_1393 [Mycobacterium bovis BCG str. Tokyo
172]
gi|121492935|emb|CAL71406.1| Conserved hypothetical protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224772875|dbj|BAH25681.1| hypothetical protein JTY_1393 [Mycobacterium bovis BCG str. Tokyo
172]
gi|341601306|emb|CCC63979.1| conserved hypothetical protein [Mycobacterium bovis BCG str.
Moreau RDJ]
Length=307
Score = 628 bits (1619), Expect = 4e-178, Method: Compositional matrix adjust.
Identities = 306/307 (99%), Positives = 307/307 (100%), Gaps = 0/307 (0%)
Query 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS
Sbjct 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
Query 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
Sbjct 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
Query 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
Sbjct 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
Query 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
Sbjct 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
Query 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVE+PSQAARLRAFGCKAAQGWHFAKAL
Sbjct 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVESPSQAARLRAFGCKAAQGWHFAKAL 300
Query 301 PVDFFRE 307
PVDFFRE
Sbjct 301 PVDFFRE 307
>gi|340626373|ref|YP_004744825.1| hypothetical protein MCAN_13751 [Mycobacterium canettii CIPT
140010059]
gi|340004563|emb|CCC43707.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=307
Score = 625 bits (1611), Expect = 3e-177, Method: Compositional matrix adjust.
Identities = 306/307 (99%), Positives = 306/307 (99%), Gaps = 0/307 (0%)
Query 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRH LSTS
Sbjct 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHCLSTS 60
Query 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
Sbjct 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
Query 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
Sbjct 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
Query 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
Sbjct 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
Query 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
Sbjct 241 LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
Query 301 PVDFFRE 307
PVDFFRE
Sbjct 301 PVDFFRE 307
>gi|308231816|ref|ZP_07413873.2| hypothetical protein TMAG_03504 [Mycobacterium tuberculosis SUMu001]
gi|308369776|ref|ZP_07419022.2| hypothetical protein TMBG_01187 [Mycobacterium tuberculosis SUMu002]
gi|308370698|ref|ZP_07422408.2| hypothetical protein TMCG_00992 [Mycobacterium tuberculosis SUMu003]
22 more sequence titles
Length=288
Score = 588 bits (1516), Expect = 4e-166, Method: Compositional matrix adjust.
Identities = 287/288 (99%), Positives = 288/288 (100%), Gaps = 0/288 (0%)
Query 20 LIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIR 79
+IDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIR
Sbjct 1 MIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIR 60
Query 80 LADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHS 139
LADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHS
Sbjct 61 LADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHS 120
Query 140 TDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQ 199
TDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQ
Sbjct 121 TDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQ 180
Query 200 ELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMI 259
ELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMI
Sbjct 181 ELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMI 240
Query 260 DLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
DLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE
Sbjct 241 DLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 288
>gi|289569370|ref|ZP_06449597.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
gi|289543124|gb|EFD46772.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
Length=272
Score = 541 bits (1393), Expect = 6e-152, Method: Compositional matrix adjust.
Identities = 263/264 (99%), Positives = 263/264 (99%), Gaps = 0/264 (0%)
Query 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS
Sbjct 1 MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS 60
Query 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
Sbjct 61 MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL 120
Query 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
Sbjct 121 TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL 180
Query 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
Sbjct 181 ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC 240
Query 241 LDGDIQARLANEQITRAMIDLGDK 264
LDGDIQARLANEQITRAMIDLGD
Sbjct 241 LDGDIQARLANEQITRAMIDLGDS 264
>gi|15827938|ref|NP_302201.1| hypothetical protein ML1752 [Mycobacterium leprae TN]
gi|221230415|ref|YP_002503831.1| hypothetical protein MLBr_01752 [Mycobacterium leprae Br4923]
gi|13093491|emb|CAC30705.1| conserved hypothetical protein [Mycobacterium leprae]
gi|219933522|emb|CAR71847.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=302
Score = 386 bits (991), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 193/265 (73%), Positives = 214/265 (81%), Gaps = 0/265 (0%)
Query 43 WADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTL 102
+ DR+Q + L + ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTL
Sbjct 38 YGHHDREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTL 97
Query 103 LPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLV 162
LP RFI AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA I DP FL
Sbjct 98 LPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLS 157
Query 163 LVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAY 222
+VE VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAY
Sbjct 158 MVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAY 217
Query 223 LPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAAR 282
L LPVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL KLGI V AK VETP QAAR
Sbjct 218 LRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAAR 277
Query 283 LRAFGCKAAQGWHFAKALPVDFFRE 307
LR FGC AAQGWHFAKALP DFF E
Sbjct 278 LRDFGCDAAQGWHFAKALPADFFTE 302
>gi|297194219|ref|ZP_06911617.1| sensory box/GGDEF family protein [Streptomyces pristinaespiralis
ATCC 25486]
gi|197722525|gb|EDY66433.1| sensory box/GGDEF family protein [Streptomyces pristinaespiralis
ATCC 25486]
Length=610
Score = 239 bits (610), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 124/256 (49%), Positives = 163/256 (64%), Gaps = 1/256 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+ +R A++RGEF L YQP++ +AD G EAL+RW HP GTL P RF+ AE
Sbjct 340 TRQALSSMLRPAVERGEFTLEYQPLVGMADGVTRGVEALVRWNHPQFGTLTPNRFVAIAE 399
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ DH P FVSVNV+ + D + V +L ET
Sbjct 400 EDGSIVQLGQWVLRTACRQARQWQLDHPDVPPLFVSVNVAVRQVWDSDLVADVAEILAET 459
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GLPAH LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 460 GLPAHLLQLELTESAVMGSAGRPLQALQALSDMGVHIAIDDFGTGYSNLAYLSRLPVSVL 519
Query 232 KLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAA 291
KL G F+ + A A+E I +A+++L +LG+TVTA+ VET QA+RLR GC
Sbjct 520 KLDGTFVRGFQDEAHANPADETIVQALVELAHRLGLTVTAECVETSGQASRLRRIGCDTG 579
Query 292 QGWHFAKALPVDFFRE 307
QGW +++A+ D E
Sbjct 580 QGWLYSRAVGPDRIAE 595
>gi|145595796|ref|YP_001160093.1| diguanylate cyclase [Salinispora tropica CNB-440]
gi|145305133|gb|ABP55715.1| diguanylate cyclase/phosphodiesterase [Salinispora tropica CNB-440]
Length=585
Score = 237 bits (604), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 131/272 (49%), Positives = 170/272 (63%), Gaps = 7/272 (2%)
Query 35 AMVANPDQWA--DSDRDQVN-TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEAL 91
A A QW D++RD+ TR L+ ++ LDRGEF+L YQP+ L D R++G EAL
Sbjct 311 AKAAGGGQWMLYDAERDRRELTRQALTAAIPAGLDRGEFYLDYQPLTSLRDGRLLGVEAL 370
Query 92 LRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVS 151
+RW HP LG L PGRFI AE GL+VPL +VL +ACR SW T PFVSVN++
Sbjct 371 VRWRHPELGVLRPGRFIGLAEETGLIVPLGGWVLAEACRTAGSW--SVTGGTPFVSVNLA 428
Query 152 ASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAID 211
+ PG + V +L TGLP LQLE+ E A +S ++ V L+ L+ LGV IAID
Sbjct 429 VRQVHRPGLVQEVRTLLRHTGLPPERLQLEITESAMMSPADEPVRALRHLADLGVRIAID 488
Query 212 DFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTA 271
DFG G+S+LAYL LPV +K+ G+F+ L Q A+E+I +++ L L +TVTA
Sbjct 489 DFGTGYSNLAYLRDLPVTELKVAGEFVAGL--RTQEPQADERIVASLVSLAHALDLTVTA 546
Query 272 KLVETPSQAARLRAFGCKAAQGWHFAKALPVD 303
+ VET QA RLRA GC AAQGWHF + P D
Sbjct 547 EGVETAGQAERLRAIGCDAAQGWHFGRPEPAD 578
>gi|294812804|ref|ZP_06771447.1| Sensory box/GGDEF family protein [Streptomyces clavuligerus ATCC
27064]
gi|326441246|ref|ZP_08215980.1| hypothetical protein SclaA2_09271 [Streptomyces clavuligerus
ATCC 27064]
gi|294325403|gb|EFG07046.1| Sensory box/GGDEF family protein [Streptomyces clavuligerus ATCC
27064]
Length=601
Score = 236 bits (602), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 125/256 (49%), Positives = 159/256 (63%), Gaps = 1/256 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ LAD G EAL+RW HP GTL P RF+ AE
Sbjct 338 TRQALSSTLRPAVERGEFALEYQPLVGLADGVTRGVEALVRWNHPEFGTLTPNRFVGIAE 397
Query 113 NNGLMVPLTAFVLEQACRHVRSW-RDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W RDH P FVSVNV+ + D + V +L ET
Sbjct 398 EDGSIVQLGRWVLRTACRQARQWQRDHPHAPPLFVSVNVAVRQVWDSDLVADVAEILAET 457
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 458 GLAPRLLQLELTESAVMGSAGRPLQALQALSDMGVQIAIDDFGTGYSNLAYLSRLPVSVL 517
Query 232 KLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAA 291
KL G F+ + A+E I AM+ L +LG+TVTA+ VET QAARLR GC
Sbjct 518 KLDGSFVRGFQDEAHPNPADETIVEAMVQLAHRLGLTVTAECVETSGQAARLRRIGCDTG 577
Query 292 QGWHFAKALPVDFFRE 307
QGW +++A+P D E
Sbjct 578 QGWLYSRAVPPDRIGE 593
>gi|302551644|ref|ZP_07303986.1| sensory box/GGDEF family protein [Streptomyces viridochromogenes
DSM 40736]
gi|302469262|gb|EFL32355.1| sensory box/GGDEF family protein [Streptomyces viridochromogenes
DSM 40736]
Length=632
Score = 236 bits (601), Expect = 5e-60, Method: Compositional matrix adjust.
Identities = 126/261 (49%), Positives = 164/261 (63%), Gaps = 6/261 (2%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR L++++R A+DRGEF L YQP++ + D+R+ G EAL+RW HP G L P RFI AE
Sbjct 356 TRQALASTLRPAIDRGEFQLEYQPLVGMEDDRLHGVEALIRWNHPQFGVLTPNRFIGLAE 415
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +VPL +VL ACR R W+ DH DP FVSVNV+ + D + V L ET
Sbjct 416 EDGSIVPLGRWVLRTACRQARRWQIDHPDDPPIFVSVNVAVRQVWDSDLVADVAETLAET 475
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + L+ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 476 GLAPGLLQLELTESAVMGSAGRPLQALKALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 535
Query 232 KLGGKFIECL---DGDIQAR--LANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286
KL G F+ D D AR A+E + AMI L +LG+TVTA+ VET +QA RLR+
Sbjct 536 KLDGSFVRGFQYDDRDTAARPNPADEVVVEAMIQLAHRLGLTVTAECVETSAQATRLRSI 595
Query 287 GCKAAQGWHFAKALPVDFFRE 307
GC QGW +++ +P D E
Sbjct 596 GCDTGQGWLYSRPVPPDRISE 616
>gi|328882651|emb|CCA55890.1| putative sensory box or GGDEF family protein [Streptomyces venezuelae
ATCC 10712]
Length=622
Score = 234 bits (597), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 122/256 (48%), Positives = 161/256 (63%), Gaps = 1/256 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ LAD + G EAL+RW HP G+L P RFI AE
Sbjct 358 TRQALSSTLRPAVERGEFTLEYQPLVELADGAVRGVEALVRWNHPQFGSLAPNRFIGIAE 417
Query 113 NNGLMVPLTAFVLEQACRHVRSWRDHSTDPQP-FVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ +P FVSVNV+ + D + V G+L ET
Sbjct 418 EDGSIVELGRWVLRTACRQARQWQKDRPRERPIFVSVNVAVRQVWDSDLVADVAGILAET 477
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL H LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 478 GLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 537
Query 232 KLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAA 291
KL G F+ + A A+E I A++ L +LG+TVTA+ VET QA+RLR GC
Sbjct 538 KLDGSFVRGFQDEEHANPADELIVEALVQLAHRLGLTVTAECVETAGQASRLRRIGCDTG 597
Query 292 QGWHFAKALPVDFFRE 307
QGW +++A+ D E
Sbjct 598 QGWLYSRAVAPDRIAE 613
>gi|297199917|ref|ZP_06917314.1| sensory box/GGDEF family protein [Streptomyces sviceus ATCC 29083]
gi|197710383|gb|EDY54417.1| sensory box/GGDEF family protein [Streptomyces sviceus ATCC 29083]
Length=631
Score = 233 bits (594), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 125/270 (47%), Positives = 171/270 (64%), Gaps = 7/270 (2%)
Query 41 DQWA--DSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHP 97
D+W D +R+ TR L++++R A++RGEF L YQP++ + D R+ G EAL+RW+HP
Sbjct 352 DRWTLFDPERNAHRMTRQALASTLRPAIERGEFRLEYQPLVCMEDGRLRGVEALIRWDHP 411
Query 98 TLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTIC 156
G L P RFI AE +G +VPL ++L ACR R W+ DH +P FVSVNV+ +
Sbjct 412 QFGMLTPNRFIQLAEEDGSIVPLGRWILATACRQARQWQLDHPDEPPIFVSVNVAVRQVW 471
Query 157 DPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIG 216
D + V L ETGL H LQLEL E A + + + LQ LS +GVGIAIDDFG G
Sbjct 472 DSDLVADVAETLAETGLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVGIAIDDFGTG 531
Query 217 FSSLAYLPRLPVDVVKLGGKFIECL--DGD-IQARLANEQITRAMIDLGDKLGITVTAKL 273
+S+LAYL RLPV V+KL G F+ +G+ + A+E + AMI L +LG+TVTA+
Sbjct 532 YSNLAYLSRLPVSVLKLDGSFVRGFQYEGEGVPPNPADEVVVEAMIQLAHRLGLTVTAEC 591
Query 274 VETPSQAARLRAFGCKAAQGWHFAKALPVD 303
VET +QA+RLR GC QGW +++ + D
Sbjct 592 VETSAQASRLRRIGCDTGQGWLYSRPVSPD 621
>gi|311896188|dbj|BAJ28596.1| putative signaling protein [Kitasatospora setae KM-6054]
Length=616
Score = 230 bits (587), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 128/265 (49%), Positives = 165/265 (63%), Gaps = 8/265 (3%)
Query 42 QWADSDRDQVN---TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPT 98
+W DRD+ TRH L+T +R A++RGEF + YQP++ LAD + GAEAL+RW HP
Sbjct 335 RWTLYDRDRGADQLTRHRLATGLRPAVERGEFTVEYQPLVGLADGAVRGAEALVRWNHPR 394
Query 99 LGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDP 158
G L P RFI AE +G +VPL +VLE++CR R W D FVSVN++ I D
Sbjct 395 YGLLSPDRFIPLAEESGAIVPLGKWVLEESCRRTREWLAEFPDRPVFVSVNLAPRQIWDS 454
Query 159 GFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFS 218
+ V VL TGLPA LQLE+ E A L + + LQ L+ +GV IAIDDFG G+S
Sbjct 455 DVVADVADVLERTGLPAPLLQLEITESALLGPAGRPLEALQALADMGVRIAIDDFGTGYS 514
Query 219 SLAYLPRLPVDVVKLGGKFIECL-----DGDIQARLANEQITRAMIDLGDKLGITVTAKL 273
+LAYL RLPV +KL FIE D D + R A+EQI AM+ L LG+TVTA+
Sbjct 515 NLAYLSRLPVHSLKLDATFIEAFRESAPDADGRRRAADEQIVGAMVQLAHALGLTVTAEG 574
Query 274 VETPSQAARLRAFGCKAAQGWHFAK 298
+E +QA RLR GC AQGW++A+
Sbjct 575 IENAAQAERLRQTGCDTAQGWYYAR 599
>gi|291439458|ref|ZP_06578848.1| sensory box/GGDEF family protein [Streptomyces ghanaensis ATCC
14672]
gi|291342353|gb|EFE69309.1| sensory box/GGDEF family protein [Streptomyces ghanaensis ATCC
14672]
Length=649
Score = 230 bits (586), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 121/260 (47%), Positives = 165/260 (64%), Gaps = 5/260 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR L++++R A++RGEF L YQP++ + D+R+ G EAL+RW HP GTL P RFI AE
Sbjct 376 TRQALASALRPAIERGEFALEYQPLVGMEDDRVHGVEALVRWNHPRFGTLTPNRFIGLAE 435
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +VPL +VL ACR R W+ +H +P FVSVNV+ I D + V G+L +T
Sbjct 436 EDGSIVPLGRWVLRTACRQARRWQEEHPEEPPIFVSVNVAVRQIRDSDLVADVAGILADT 495
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + L+ELS +GV IAIDDFG G+S+LA L RLPV V+
Sbjct 496 GLAPRLLQLELTESAVMGSSGRPLQVLRELSDMGVRIAIDDFGTGYSNLANLSRLPVSVL 555
Query 232 KLGGKFIECLDGDIQA----RLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFG 287
KL G F+ + ++ A+E I AM+ L +LG+TVTA+ VET +QA RLR G
Sbjct 556 KLDGAFVRGFPYEERSAAPPNPADEVIVEAMVQLAHRLGLTVTAECVETSAQATRLRRIG 615
Query 288 CKAAQGWHFAKALPVDFFRE 307
C QGW +++ +P D E
Sbjct 616 CDTGQGWLYSRPVPPDRISE 635
>gi|302560492|ref|ZP_07312834.1| sensory box/GGDEF family protein [Streptomyces griseoflavus Tu4000]
gi|302478110|gb|EFL41203.1| sensory box/GGDEF family protein [Streptomyces griseoflavus Tu4000]
Length=630
Score = 229 bits (584), Expect = 5e-58, Method: Compositional matrix adjust.
Identities = 121/260 (47%), Positives = 161/260 (62%), Gaps = 5/260 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR L++++R A+DRGEF L YQP++ + D+R+ G EAL+RW HP GTL P RFI AE
Sbjct 357 TRQALASTLRPAIDRGEFALEYQPLVGMEDDRVHGVEALVRWHHPRFGTLTPNRFISLAE 416
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +VPL +VL ACR R W+ H +P FVSVNV+ + D + V L ET
Sbjct 417 EDGSIVPLGRWVLRTACRQARDWQVAHPDEPPIFVSVNVAVRQVWDSDLVADVAATLEET 476
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + L+ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 477 GLAPRLLQLELTESAVMGSSGRPIQALKALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 536
Query 232 KLGGKFIECLDGDIQA----RLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFG 287
KL G F+ + +A A+E I AM+ L +LG+TVTA+ VET +QA RLR G
Sbjct 537 KLDGSFVRGFQYEERAAAPPNPADEVIVEAMVQLAHRLGLTVTAECVETSAQATRLRRIG 596
Query 288 CKAAQGWHFAKALPVDFFRE 307
C QGW +++ + D E
Sbjct 597 CDTGQGWLYSRPVSPDRISE 616
>gi|159039053|ref|YP_001538306.1| diguanylate cyclase/phosphodiesterase [Salinispora arenicola
CNS-205]
gi|157917888|gb|ABV99315.1| diguanylate cyclase/phosphodiesterase [Salinispora arenicola
CNS-205]
Length=594
Score = 228 bits (581), Expect = 9e-58, Method: Compositional matrix adjust.
Identities = 127/276 (47%), Positives = 171/276 (62%), Gaps = 9/276 (3%)
Query 28 RGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIG 87
+ A R M+ +P++ DR ++ TR L+ ++ LDRGEF+L YQP+ L D R++G
Sbjct 321 KAAGGGRWMIYDPER----DRREL-TRQALTAAIPTGLDRGEFYLDYQPLTSLRDGRLLG 375
Query 88 AEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVS 147
EAL+RW HP LG L P +FI AE GL+VPL +VL +ACR SW T +PFVS
Sbjct 376 VEALVRWRHPELGVLRPDQFIGLAEETGLIVPLGGWVLAEACRVAGSW--SGTGGEPFVS 433
Query 148 VNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVG 207
VN++ + PG + V +L TGLP LQLE+ E A +S E+ V L+ L+ LGV
Sbjct 434 VNLAVRQVHRPGLVRDVRDLLRHTGLPPERLQLEITESAMMSPAEEPVRALRMLADLGVR 493
Query 208 IAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGI 267
IAIDDFG G+S+LAYL LPV +K+ G+F+ L A+E+I +++ L L +
Sbjct 494 IAIDDFGTGYSNLAYLRDLPVTELKVAGEFVAGLRASEPQ--ADERILASLVSLAHALNL 551
Query 268 TVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVD 303
TVTA+ VET QA RLRA GC A QGWHF + P D
Sbjct 552 TVTAEGVETAGQAERLRAIGCDAGQGWHFGRPEPAD 587
>gi|297160240|gb|ADI09952.1| sensory box/GGDEF family protein [Streptomyces bingchenggensis
BCW-1]
Length=624
Score = 228 bits (580), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 117/252 (47%), Positives = 158/252 (63%), Gaps = 2/252 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++R EF L YQP++ L D + G EAL+RWEHP G L P RFI AE
Sbjct 358 TRQALSSTLRPAVEREEFVLDYQPLVGLVDGVVKGVEALVRWEHPRFGRLSPNRFISLAE 417
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
NG +VPL +VL ACR R+W+ H +P VSVNV+ + D + V +L ET
Sbjct 418 ENGAIVPLGRWVLRTACRQARAWQLAHPLNPL-IVSVNVAVRQVWDSDLVAEVGSILAET 476
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GLP H LQLEL E A + + + L LS +GV IAIDDFG G+S+LAYL RLPV +
Sbjct 477 GLPPHLLQLELTESAVMGSAGRPLQALLRLSEMGVAIAIDDFGTGYSNLAYLSRLPVSTL 536
Query 232 KLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAA 291
KL G F++ + A+E I +A+++L +LG+TVTA+ VE+ QA RL GC
Sbjct 537 KLDGSFVQGFRAEEHPNPADETIVQALVELAHRLGLTVTAECVESAEQAERLARIGCDTG 596
Query 292 QGWHFAKALPVD 303
QGW +++ +P D
Sbjct 597 QGWFYSRPVPPD 608
>gi|345015412|ref|YP_004817766.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase
[Streptomyces violaceusniger Tu 4113]
gi|344041761|gb|AEM87486.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces violaceusniger Tu 4113]
Length=656
Score = 227 bits (578), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 116/251 (47%), Positives = 155/251 (62%), Gaps = 0/251 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++R EF L YQP++ L D + G EAL+RW+HP G L P RFI AE
Sbjct 394 TRQALSSTLRPAVERDEFVLDYQPLVGLGDGVVRGVEALVRWDHPQFGRLSPNRFIPLAE 453
Query 113 NNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETG 172
NG +VPL +VL ACR R W+ + VSVNV+ + D + V +L ETG
Sbjct 454 ENGAIVPLGRWVLRTACRQARVWQLANPTHPLVVSVNVAVRQVWDSDLVADVGTILAETG 513
Query 173 LPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVK 232
LP H LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV +K
Sbjct 514 LPPHLLQLELTESAVMGSTGRPLQALQRLSDMGVPIAIDDFGTGYSNLAYLSRLPVSTLK 573
Query 233 LGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQ 292
L G F++ + A+E I A++ L +LG+TVTA+ VE+ QA RLR GC Q
Sbjct 574 LDGSFVQGFRAEEHPNPADETIVEALVQLAHRLGLTVTAECVESAEQAERLRRIGCDTGQ 633
Query 293 GWHFAKALPVD 303
GW +++ +P D
Sbjct 634 GWFYSRPVPPD 644
>gi|294629517|ref|ZP_06708077.1| developmental regulator MorA [Streptomyces sp. e14]
gi|292832850|gb|EFF91199.1| developmental regulator MorA [Streptomyces sp. e14]
Length=626
Score = 226 bits (575), Expect = 5e-57, Method: Compositional matrix adjust.
Identities = 125/271 (47%), Positives = 164/271 (61%), Gaps = 8/271 (2%)
Query 45 DSDRDQVN-TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLL 103
D +R+ TR L +++R A++RGEF L YQP++ +AD R+ G EAL+RW HP G L
Sbjct 346 DPERNATRMTRQALVSTLRAAVERGEFTLEYQPLVAMADGRLRGVEALVRWRHPQFGVLT 405
Query 104 PGRFIDRAENNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLV 162
P RFI AE +G +VPL ++L ACR R W+ DH +P FVSVNV+ + D +
Sbjct 406 PNRFITLAEEDGSIVPLGRWILATACRQARRWQLDHPDEPPIFVSVNVAVRQVWDSDLVA 465
Query 163 LVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAY 222
V VL ETGL LQLEL E A + + + L+ LS +GV IAIDDFG G+S+LAY
Sbjct 466 DVAEVLAETGLAPRLLQLELTESAVMGSAGRPLEALRALSDMGVTIAIDDFGTGYSNLAY 525
Query 223 LPRLPVDVVKLGGKFIECLDGDIQ---ARL---ANEQITRAMIDLGDKLGITVTAKLVET 276
L RLPV +KL G F+ Q A L A+E I AMI L +LG+TVTA+ VET
Sbjct 526 LSRLPVSALKLDGSFVRGFQPGRQTGEAELPSPADEVIVEAMIQLAHRLGLTVTAECVET 585
Query 277 PSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
QA+RLR GC QGW +++ + D E
Sbjct 586 SDQASRLRRIGCDTGQGWLYSRPVSPDRISE 616
>gi|29831780|ref|NP_826414.1| sensory box/GGDEF family protein [Streptomyces avermitilis MA-4680]
gi|29608897|dbj|BAC72949.1| putative sensory box/GGDEF family protein [Streptomyces avermitilis
MA-4680]
Length=620
Score = 225 bits (574), Expect = 5e-57, Method: Compositional matrix adjust.
Identities = 123/265 (47%), Positives = 161/265 (61%), Gaps = 10/265 (3%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+ +R A++ GEF L YQP++ + D R+ G EAL+RW HP G L P RFI AE
Sbjct 342 TRQALSSGLRPAIEHGEFVLEYQPLVGMEDGRLRGVEALVRWNHPQFGMLTPNRFIGLAE 401
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ +H P FVSVNV+ + D + V +L ET
Sbjct 402 EDGSIVQLGRWVLATACRQARRWQLEHPDAPPLFVSVNVAVRQVWDSDLVTDVAEILAET 461
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL H LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 462 GLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVHIAIDDFGTGYSNLAYLSRLPVSVL 521
Query 232 KLGGKFI--------ECLDG-DIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAAR 282
KL G F+ E DG D + A+E + AMI L +LG+TVTA+ VET +QA+R
Sbjct 522 KLDGSFVRGFQYDTSEKHDGTDARPNPADEVVVEAMIQLAHRLGLTVTAECVETSAQASR 581
Query 283 LRAFGCKAAQGWHFAKALPVDFFRE 307
LR GC QGW +++ + D E
Sbjct 582 LRGIGCDTGQGWLYSRPVAPDRISE 606
>gi|256380853|ref|YP_003104513.1| PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase
[Actinosynnema mirum DSM 43827]
gi|255925156|gb|ACU40667.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Actinosynnema mirum DSM 43827]
Length=720
Score = 225 bits (573), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 119/262 (46%), Positives = 162/262 (62%), Gaps = 3/262 (1%)
Query 42 QWA--DSDRDQVN-TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPT 98
+WA D DR+ R LS +M AL+R EF++ YQP++RL + R++G EAL+RW+HP
Sbjct 448 RWALYDPDRNAKEIARFTLSATMPAALERDEFYVDYQPLVRLENARVVGVEALVRWQHPE 507
Query 99 LGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDP 158
G L P RFI+ AE GL+VPL +VL +AC R W D + P+VSVN++ DP
Sbjct 508 FGRLAPDRFIELAEETGLIVPLGRWVLRKACEQGRRWLDEFAELAPYVSVNLAVRQSRDP 567
Query 159 GFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFS 218
+ V+ +L ETGLP LQLEL E A + ++ + L+ LS +GV IAIDDFG G+S
Sbjct 568 ELVRDVKRILDETGLPPRHLQLELTESAIMGTADEPLEALRALSDMGVRIAIDDFGTGYS 627
Query 219 SLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPS 278
+LAYL LPV +K+ G F+E L + + QI ++ L LG+ VTA+ VETPS
Sbjct 628 NLAYLKHLPVHELKIAGSFMEGLRAADEEDPVDAQIVSTLVQLAHALGLGVTAEGVETPS 687
Query 279 QAARLRAFGCKAAQGWHFAKAL 300
QA RL GC QGW +AK +
Sbjct 688 QAKRLHRIGCDTGQGWFYAKPM 709
>gi|302545149|ref|ZP_07297491.1| developmental regulator MorA [Streptomyces hygroscopicus ATCC
53653]
gi|302462767|gb|EFL25860.1| developmental regulator MorA [Streptomyces himastatinicus ATCC
53653]
Length=547
Score = 224 bits (570), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 113/251 (46%), Positives = 155/251 (62%), Gaps = 0/251 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++R EF L YQP++ L D + G EAL+RW+HP G L P RF+ AE
Sbjct 285 TRQALSSTLRPAVEREEFVLDYQPLVGLVDGVVRGVEALVRWDHPQFGRLSPNRFVSLAE 344
Query 113 NNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETG 172
NG +VPL +VL ACR R+W+ VSVNV+ + D + V +L ETG
Sbjct 345 ENGAIVPLGRWVLRTACRQARAWQQAHPRHPLVVSVNVAVRQVWDSDLVADVGTILAETG 404
Query 173 LPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVK 232
LP LQLEL E A + + + LQ+LS +GV IAIDDFG G+S+LAYL RLPV +K
Sbjct 405 LPPRLLQLELTESAVMGSAGRPLQALQQLSDMGVAIAIDDFGTGYSNLAYLSRLPVSTLK 464
Query 233 LGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQ 292
L G F++ + A+E I RA+++L +LG+TV A+ VE+ QA RL GC Q
Sbjct 465 LDGSFVQGFRAEEHPNPADETIVRALVELAHRLGLTVVAECVESAEQAERLGRIGCDTGQ 524
Query 293 GWHFAKALPVD 303
GW +++ +P D
Sbjct 525 GWFYSRPVPPD 535
>gi|330469358|ref|YP_004407101.1| diguanylate cyclase/phosphodiesterase [Verrucosispora maris AB-18-032]
gi|328812329|gb|AEB46501.1| diguanylate cyclase/phosphodiesterase [Verrucosispora maris AB-18-032]
Length=621
Score = 223 bits (569), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 125/268 (47%), Positives = 168/268 (63%), Gaps = 9/268 (3%)
Query 43 WA--DSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTL 99
WA D++RD + R LS ++ L+RGEF+L YQP+ L D ++G EAL+RW+HP L
Sbjct 319 WALYDAERDSREQARQALSAAIPGGLERGEFYLDYQPLTSLQDGSVLGVEALVRWQHPQL 378
Query 100 GTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPG 159
G L P FI AE GL+VPL ++VL +ACR W + +P P+VSVN++ + P
Sbjct 379 GVLRPDSFIGLAEETGLIVPLGSWVLAEACREAVGWSAATGEP-PYVSVNLAVRQLRRPD 437
Query 160 FLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSS 219
+ V G+L TGLP + LQLE+ E +S E+ V L+ L+ LGV IAIDDFG G+S+
Sbjct 438 LVQEVCGLLRRTGLPPNRLQLEITESMMMSSAEEPVRALRALADLGVRIAIDDFGTGYSN 497
Query 220 LAYLPRLPVDVVKLGGKFIECLD----GDIQARLANEQITRAMIDLGDKLGITVTAKLVE 275
LAYL LPV +K+ G+F+ L D +R A+E+I AM+ L LG+TVTA+ VE
Sbjct 498 LAYLRDLPVTELKVAGEFVRGLRAPEAADPGSR-ADERILAAMVSLAHALGLTVTAEGVE 556
Query 276 TPSQAARLRAFGCKAAQGWHFAKALPVD 303
T QA RLRA GC A QGWH + P D
Sbjct 557 TAEQADRLRAIGCDAGQGWHLGRPAPAD 584
>gi|238060306|ref|ZP_04605015.1| diguanylate cyclase/phosphodiesterase [Micromonospora sp. ATCC
39149]
gi|237882117|gb|EEP70945.1| diguanylate cyclase/phosphodiesterase [Micromonospora sp. ATCC
39149]
Length=611
Score = 223 bits (568), Expect = 3e-56, Method: Compositional matrix adjust.
Identities = 125/272 (46%), Positives = 167/272 (62%), Gaps = 6/272 (2%)
Query 35 AMVANPDQWA--DSDRDQVN-TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEAL 91
A A +W D+DR++ R+ LS ++ AL+RGEF L YQP+ L D R++G EAL
Sbjct 332 AKAAGGARWTLFDADRNRRELARYALSAAIPAALERGEFQLDYQPLTSLRDGRVLGVEAL 391
Query 92 LRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVS 151
+RW HP LG L PG FI+ AE GL+VPL ++VL +ACR +W T PFVSVN++
Sbjct 392 VRWRHPELGKLYPGSFIELAEETGLIVPLGSWVLAEACREAATWSSFGT-AAPFVSVNLA 450
Query 152 ASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAID 211
+ PG + V VL TGLP LQLE+ E +S E+ V L+ L+ +G+ IAID
Sbjct 451 VRQVHRPGLVREVRDVLERTGLPPERLQLEVTESTMMSAVEEPVRALRVLADMGMRIAID 510
Query 212 DFGIGFSSLAYLPRLPVDVVKLGGKFIECL--DGDIQARLANEQITRAMIDLGDKLGITV 269
DFG G+ +LAYL LPV +K+ G+F+ L D A +E+I +++ L L +TV
Sbjct 511 DFGTGYCNLAYLRDLPVTELKVAGEFVAGLRAPADDPASRTDERILASLVSLAHALDLTV 570
Query 270 TAKLVETPSQAARLRAFGCKAAQGWHFAKALP 301
TA+ VET QA RLR GC AAQGWHF K P
Sbjct 571 TAEGVETEGQADRLRTIGCDAAQGWHFGKPAP 602
>gi|329937967|ref|ZP_08287449.1| putative sensory box/GGDEF family protein [Streptomyces griseoaurantiacus
M045]
gi|329302924|gb|EGG46813.1| putative sensory box/GGDEF family protein [Streptomyces griseoaurantiacus
M045]
Length=671
Score = 223 bits (568), Expect = 3e-56, Method: Compositional matrix adjust.
Identities = 121/267 (46%), Positives = 158/267 (60%), Gaps = 16/267 (5%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR L++++R +++GEF L YQP++ + D R+ G EAL+RW HP G L P RFI AE
Sbjct 389 TRQALASTLRPGIEQGEFALEYQPLVSMTDGRVRGVEALVRWHHPQFGALAPNRFISLAE 448
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +VPL +VL ACR R W+ DH P FVSVNV+ I D + V L ET
Sbjct 449 EDGSIVPLGRWVLTTACRQARRWQLDHPDAPPLFVSVNVAVRQIWDSDLVADVARTLAET 508
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GLP H LQLEL E A + + L+ LS +GV IAIDDFG G+S+LAYL RLPV+V+
Sbjct 509 GLPPHLLQLELTESALTGSAGRPLQALEALSDMGVRIAIDDFGTGYSNLAYLSRLPVNVL 568
Query 232 KLGGKFIECLD---------------GDIQARLANEQITRAMIDLGDKLGITVTAKLVET 276
KL G F+ A A+E I AM+ L +LG+TV A+ VET
Sbjct 569 KLDGSFVRGFQYEAPAAGGAAPEPGAEGAPASPADEVIVEAMVQLAHRLGLTVIAECVET 628
Query 277 PSQAARLRAFGCKAAQGWHFAKALPVD 303
+QAARLRA GC QGW +++ + D
Sbjct 629 SAQAARLRAIGCDTGQGWLYSRPVSPD 655
>gi|337765894|emb|CCB74603.1| Sensory box/GGDEF family protein [Streptomyces cattleya NRRL
8057]
Length=619
Score = 222 bits (566), Expect = 5e-56, Method: Compositional matrix adjust.
Identities = 119/252 (48%), Positives = 155/252 (62%), Gaps = 2/252 (0%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ L R+ G EAL+RWEHP G L P RFI AE
Sbjct 360 TRQSLSSTLRQAVERGEFTLEYQPLVALDGGRLRGVEALVRWEHPRFGRLAPNRFISLAE 419
Query 113 NNGLMVPLTAFVLEQACRHVRSW-RDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
NG +V L +VL ++CR R+W +DH P PFVSVNV+ + D + V VL ET
Sbjct 420 ENGSIVQLGRWVLAESCRWARAWHKDHPEAP-PFVSVNVAVRQVWDSDLVGDVAAVLDET 478
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GLP LQLEL E A + + + L L +GV IAIDDFG G+S+LAYL RLPV +
Sbjct 479 GLPPALLQLELTESAVMGSTGRPLQALYALHEMGVRIAIDDFGTGYSNLAYLSRLPVTAL 538
Query 232 KLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAA 291
KL G F+ A+E I A++ L +LGITVTA+ VE+ QA RLR GC
Sbjct 539 KLDGSFVRGFRSREHPNPADETIVEALVQLAHRLGITVTAECVESAEQAERLRRIGCDTG 598
Query 292 QGWHFAKALPVD 303
QGW +++ + D
Sbjct 599 QGWFYSRPVAPD 610
>gi|302869003|ref|YP_003837640.1| diguanylate cyclase [Micromonospora aurantiaca ATCC 27029]
gi|315504526|ref|YP_004083413.1| diguanylate cyclase/phosphodiesterase [Micromonospora sp. L5]
gi|302571862|gb|ADL48064.1| diguanylate cyclase [Micromonospora aurantiaca ATCC 27029]
gi|315411145|gb|ADU09262.1| diguanylate cyclase/phosphodiesterase [Micromonospora sp. L5]
Length=586
Score = 222 bits (566), Expect = 5e-56, Method: Compositional matrix adjust.
Identities = 124/270 (46%), Positives = 166/270 (62%), Gaps = 6/270 (2%)
Query 35 AMVANPDQWA--DSDRDQVN-TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEAL 91
A A +W+ D+DR++ + R+ LS ++ ALDRGEF+L YQP+ L D R++G EAL
Sbjct 304 AKAAGGARWSLFDADRNRRDLARYALSAAIPAALDRGEFYLDYQPLTSLRDGRVLGMEAL 363
Query 92 LRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVS 151
+RW HP LG L P FI AE GL+V L ++VL +ACR +W D D PFVSVN++
Sbjct 364 VRWRHPELGVLRPDSFIPLAEETGLIVRLGSWVLAEACREAGTWPDAEGD-APFVSVNLA 422
Query 152 ASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAID 211
+ + V GVLG TGLP H LQLE+ E +S + V L+ L LGV +AID
Sbjct 423 VRQLHRTDLVTEVRGVLGRTGLPPHRLQLEITESTMMSTVVEPVRALRVLGDLGVRVAID 482
Query 212 DFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTA 271
DFG G+ +LAYL LPVD +K+ G+F+ L +E+I +++ L L +TVTA
Sbjct 483 DFGTGYCNLAYLRDLPVDELKVAGEFVTGLRAPGSG--TDERILASLVSLAHALDLTVTA 540
Query 272 KLVETPSQAARLRAFGCKAAQGWHFAKALP 301
+ VET QA RLRA GC A QGWHF + P
Sbjct 541 EGVETADQADRLRAIGCDAGQGWHFGRPGP 570
>gi|182438510|ref|YP_001826229.1| hypothetical protein SGR_4717 [Streptomyces griseus subsp. griseus
NBRC 13350]
gi|178467026|dbj|BAG21546.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus
NBRC 13350]
Length=611
Score = 221 bits (563), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 118/252 (47%), Positives = 157/252 (63%), Gaps = 5/252 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ +AD + G EAL+RW HP G L P RF+ AE
Sbjct 345 TRQSLSSTLRPAVERGEFTLEYQPLVGMADGVLRGVEALVRWNHPQFGVLPPNRFVQIAE 404
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L ++L ACR R W DH +P F+SVNV+ + D + V +L ET
Sbjct 405 EDGSIVQLGRWILRTACRQARRWELDHPDEPPLFISVNVAVRQVWDSDLVADVAQILAET 464
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 465 GLAPGLLQLELTESAVMGSGGRPLRALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 524
Query 232 KLGGKFIECL---DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGC 288
KL G F++ DG A+E I AM+ L +LG+TVTA+ VET QA RLR GC
Sbjct 525 KLDGAFVKGFRYEDG-THPSPADETIVEAMVQLAHRLGLTVTAECVETAGQAERLRRIGC 583
Query 289 KAAQGWHFAKAL 300
QGW +++A+
Sbjct 584 DTGQGWLYSRAV 595
>gi|326779157|ref|ZP_08238422.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces cf. griseus XylebKG-1]
gi|326659490|gb|EGE44336.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces griseus XylebKG-1]
Length=641
Score = 221 bits (563), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 118/252 (47%), Positives = 157/252 (63%), Gaps = 5/252 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ +AD + G EAL+RW HP G L P RF+ AE
Sbjct 375 TRQSLSSTLRPAVERGEFTLEYQPLVGMADGVLRGVEALVRWNHPQFGVLPPNRFVQIAE 434
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L ++L ACR R W DH +P F+SVNV+ + D + V +L ET
Sbjct 435 EDGSIVQLGRWILRTACRQARRWELDHPDEPPLFISVNVAVRQVWDSDLVADVAQILAET 494
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 495 GLAPGLLQLELTESAVMGSGGRPLRALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 554
Query 232 KLGGKFIECL---DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGC 288
KL G F++ DG A+E I AM+ L +LG+TVTA+ VET QA RLR GC
Sbjct 555 KLDGAFVKGFRYEDG-THPSPADETIVEAMVQLAHRLGLTVTAECVETAGQAERLRRIGC 613
Query 289 KAAQGWHFAKAL 300
QGW +++A+
Sbjct 614 DTGQGWLYSRAV 625
>gi|254387213|ref|ZP_05002479.1| sensory box/GGDEF protein [Streptomyces sp. Mg1]
gi|194346024|gb|EDX26990.1| sensory box/GGDEF protein [Streptomyces sp. Mg1]
Length=635
Score = 220 bits (560), Expect = 3e-55, Method: Compositional matrix adjust.
Identities = 119/256 (47%), Positives = 156/256 (61%), Gaps = 3/256 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ L + G EAL+RW HP GTL P RFI AE
Sbjct 355 TRQALSSTLRPAVERGEFALEYQPLVDLESGAVRGVEALVRWNHPQFGTLTPNRFIGIAE 414
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ + +D FVSVNV+ + D + V +L ET
Sbjct 415 EDGSIVQLGRWVLRTACRQARRWQIEQPSDAPVFVSVNVAVRQVWDSDLVGDVAEILAET 474
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 475 GLAPQLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 534
Query 232 KLGGKFIECL--DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCK 289
KL G F+ D A+E I A++ L +LG+TVTA+ VET QAARLR GC
Sbjct 535 KLDGSFVRGFRYDDGAHPNPADETIVEALVQLAHRLGLTVTAECVETVGQAARLRRVGCD 594
Query 290 AAQGWHFAKALPVDFF 305
QGW +++A+ D
Sbjct 595 TGQGWLYSRAVAPDVI 610
>gi|239987963|ref|ZP_04708627.1| hypothetical protein SrosN1_11697 [Streptomyces roseosporus NRRL
11379]
gi|291444943|ref|ZP_06584333.1| sensory box/GGDEF family protein [Streptomyces roseosporus NRRL
15998]
gi|291347890|gb|EFE74794.1| sensory box/GGDEF family protein [Streptomyces roseosporus NRRL
15998]
Length=639
Score = 218 bits (556), Expect = 6e-55, Method: Compositional matrix adjust.
Identities = 118/252 (47%), Positives = 157/252 (63%), Gaps = 5/252 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A++RGEF L YQP++ +AD + G EAL+RW HP G L P RF+ AE
Sbjct 373 TRQSLSSTLRPAVERGEFTLEYQPLVGMADGVLRGVEALVRWNHPQFGVLPPNRFVQIAE 432
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ DH +P F+SVNV+ + D + V +L ET
Sbjct 433 EDGSIVQLGRWVLRTACRQARRWQLDHPDEPPLFISVNVAVRQVWDSDLVADVAQILAET 492
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
L LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 493 ELAPGLLQLELTESAVMGSGGRPLRALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 552
Query 232 KLGGKFIECL---DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGC 288
KL G F++ DG A+E I AM+ L +LG+TVTA+ VET QA RLR GC
Sbjct 553 KLDGAFVKGFRYEDG-THPSPADETIVEAMVQLAHRLGLTVTAECVETAGQAERLRRIGC 611
Query 289 KAAQGWHFAKAL 300
QGW +++A+
Sbjct 612 DTGQGWLYSRAV 623
>gi|344999882|ref|YP_004802736.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase
[Streptomyces sp. SirexAA-E]
gi|344315508|gb|AEN10196.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces sp. SirexAA-E]
Length=611
Score = 218 bits (555), Expect = 9e-55, Method: Compositional matrix adjust.
Identities = 119/251 (48%), Positives = 156/251 (63%), Gaps = 3/251 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS ++R A++R EF L YQP++ +AD + G EAL+RW HP G L P RF+ AE
Sbjct 345 TRQALSATLRAAVERREFTLEYQPLVGMADGVVRGVEALVRWNHPRFGMLAPHRFVPIAE 404
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ +H +P F+SVNV+ + D + V VL ET
Sbjct 405 EDGSIVQLGRWVLRTACRQARRWQLEHPAEPALFISVNVAVRQLWDSDLVADVAEVLAET 464
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + LQELS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 465 GLAPGLLQLELTESAVTGSAGRPLRVLQELSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 524
Query 232 KLGGKFIECLDGDIQARL--ANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCK 289
KL G F+ + AR A+E I AM+ L +LG+TVTA+ VET QA RLR GC
Sbjct 525 KLDGSFVRGFRQEDGARSSPADETIVEAMVQLAHRLGLTVTAECVETSGQAERLRRIGCD 584
Query 290 AAQGWHFAKAL 300
QGW +++A+
Sbjct 585 TGQGWLYSRAV 595
>gi|134103559|ref|YP_001109220.1| diguanylate cyclase/phosphodiesterase [Saccharopolyspora erythraea
NRRL 2338]
gi|291008080|ref|ZP_06566053.1| diguanylate cyclase/phosphodiesterase [Saccharopolyspora erythraea
NRRL 2338]
gi|133916182|emb|CAM06295.1| diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains)
with PAS/PAC sensor(s) [Saccharopolyspora erythraea NRRL
2338]
Length=687
Score = 218 bits (554), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 121/260 (47%), Positives = 159/260 (62%), Gaps = 3/260 (1%)
Query 42 QWA--DSDRDQVNTRHY-LSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPT 98
QWA D DR+ + LS M ALD EF++ YQP+I L D ++G EAL+RW HP
Sbjct 412 QWALFDPDRNATEVAQFRLSAKMPAALDSEEFYVEYQPLIGLRDFGVVGVEALVRWWHPE 471
Query 99 LGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDP 158
LG L P RFI AE GL+VPL +VL QACR R W+D D PFVSVN++ DP
Sbjct 472 LGRLGPDRFIGLAEETGLIVPLGRWVLRQACRQARQWQDEFGDAAPFVSVNLAVRQSRDP 531
Query 159 GFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFS 218
+ V +L ETGL LQLEL E A + ++ + L+ LS +GV IAIDDFG G+S
Sbjct 532 NLVDDVAAILRETGLEPSRLQLELTESAIMGTADEPLDALRALSRMGVRIAIDDFGTGYS 591
Query 219 SLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPS 278
+LAYL LPV +K+ G F+E L +A + +I ++DL LG+TVTA+ VET +
Sbjct 592 NLAYLRHLPVHELKIAGSFMEGLRDAERADPVDARIVGTLVDLAHALGLTVTAEGVETHA 651
Query 279 QAARLRAFGCKAAQGWHFAK 298
QA R+ GC+ QG+ FA+
Sbjct 652 QARRVADIGCETGQGYFFAR 671
>gi|331697858|ref|YP_004334097.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase
[Pseudonocardia dioxanivorans CB1190]
gi|326952547|gb|AEA26244.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Pseudonocardia dioxanivorans CB1190]
Length=714
Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 117/265 (45%), Positives = 157/265 (60%), Gaps = 6/265 (2%)
Query 42 QWADSDRDQVN---TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPT 98
+WA D ++ TR L+ ++ L+R EF + YQPI+RL D + G EAL+RW+HPT
Sbjct 440 RWAQYDPERAALDMTRFTLTATLAAGLERDEFEVEYQPIVRLDDGAVAGVEALVRWDHPT 499
Query 99 LGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDP 158
LG L P RFI+ AE G +VPL VL +ACR W + FVSVN++ DP
Sbjct 500 LGRLGPDRFIEVAEETGAIVPLGRHVLREACRRAARWNAENPGADLFVSVNLAVRQAHDP 559
Query 159 GFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFS 218
+ V +L +TGLP H LQLEL E A L + V + L+ LG+ IA+DDFG G+S
Sbjct 560 ALVSDVADILADTGLPPHLLQLELTESALLGPAGRPVDAIGALADLGIRIAVDDFGTGYS 619
Query 219 SLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPS 278
+L YLPRLP+ +KL G +E L +I +++ L LG+TVT + VETP+
Sbjct 620 NLGYLPRLPLHSLKLAGVLVEGLRSPTA---GASRIVTSLVALAHALGLTVTGEGVETPA 676
Query 279 QAARLRAFGCKAAQGWHFAKALPVD 303
QAARLR GC AQGW +A+ P D
Sbjct 677 QAARLRTAGCDTAQGWLYARPAPWD 701
>gi|302534564|ref|ZP_07286906.1| sensory box/GGDEF protein [Streptomyces sp. C]
gi|302443459|gb|EFL15275.1| sensory box/GGDEF protein [Streptomyces sp. C]
Length=623
Score = 216 bits (550), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 117/251 (47%), Positives = 154/251 (62%), Gaps = 3/251 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+S+R A++RGEF L YQP++ L + G EAL+RW HP G L P RFI AE
Sbjct 348 TRQALSSSLRPAVERGEFELEYQPLVDLESGVVRGVEALVRWNHPQFGMLTPNRFIGIAE 407
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL ACR R W+ + +D FVSVNV+ + D + V +L ET
Sbjct 408 EDGSIVQLGQWVLRTACRQARRWQVEQPSDSPVFVSVNVAVRQVWDSDLVGDVAEILAET 467
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 468 GLAPQLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 527
Query 232 KLGGKFIECL--DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCK 289
KL G F+ + A+E I A++ L +LG+TVTA+ VET QAARLR GC
Sbjct 528 KLDGSFVRGFRYEEGTHPNPADETIVEALVQLAHRLGLTVTAECVETAGQAARLRRVGCD 587
Query 290 AAQGWHFAKAL 300
QGW +++A+
Sbjct 588 TGQGWLYSRAV 598
>gi|21221267|ref|NP_627046.1| hypothetical protein SCO2817 [Streptomyces coelicolor A3(2)]
gi|289771443|ref|ZP_06530821.1| sensory box/GGDEF family protein [Streptomyces lividans TK24]
gi|14799963|emb|CAC44280.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
gi|289701642|gb|EFD69071.1| sensory box/GGDEF family protein [Streptomyces lividans TK24]
Length=634
Score = 214 bits (546), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 117/262 (45%), Positives = 155/262 (60%), Gaps = 11/262 (4%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR L+ ++R A++RGEF L YQP++ + D R+ G EAL+RW HP G L P RFI AE
Sbjct 349 TRQALAATLRPAIERGEFALEYQPLVGMEDGRVRGVEALIRWNHPQFGVLAPNRFIALAE 408
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +VPL ++L AC R W+ H +P FVSVNV+ + D + V L ET
Sbjct 409 EDGSIVPLGRWILRTACHQARRWQLAHPDEPPIFVSVNVAVRQVWDSDLVADVARTLEET 468
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + L+ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 469 GLAPELLQLELTESAVMGSAGRPLQVLKALSDMGVHIAIDDFGTGYSNLAYLSRLPVSVL 528
Query 232 KLGGKFIECLDGD----------IQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAA 281
KL G F+ D A A+E I AM+ L +LG+TVTA+ VET +QA
Sbjct 529 KLDGAFVRGFQYDAVSDAAACGAGGANPADEVIVEAMVQLAHRLGLTVTAECVETSAQAT 588
Query 282 RLRAFGCKAAQGWHFAKALPVD 303
RLR GC QGW +++ + D
Sbjct 589 RLRRIGCDTGQGWLYSRPVAPD 610
>gi|320010638|gb|ADW05488.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces flavogriseus ATCC 33331]
Length=621
Score = 214 bits (545), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 116/252 (47%), Positives = 156/252 (62%), Gaps = 5/252 (1%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++ A++RGEF L YQP++ +AD + G EAL+RW HP G L P RF+ AE
Sbjct 355 TRQALSSTLLPAVERGEFTLEYQPLVGMADGIVRGVEALVRWNHPRFGLLAPSRFVPIAE 414
Query 113 NNGLMVPLTAFVLEQACRHVRSWR-DHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L +VL AC R W+ +H DP F+SVNV+ + D + V +L ET
Sbjct 415 EDGTIVQLGRWVLRSACLQARRWQLEHPEDPALFISVNVAVRQLWDSDLVADVAEILAET 474
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL LQLEL E A + + + LQ LS +G+ IAIDDFG G+S+LAYL RLPV V+
Sbjct 475 GLEPGLLQLELTESAVMGSPGRPLRVLQALSDMGIRIAIDDFGTGYSNLAYLSRLPVSVL 534
Query 232 KLGGKFIECL---DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGC 288
KL G F+ DG + A+E I AM+ L +LG+TVTA+ VET QA RLR GC
Sbjct 535 KLDGSFVRGFRYEDG-AHSSPADETIVEAMVQLAHRLGLTVTAECVETSGQAERLRRIGC 593
Query 289 KAAQGWHFAKAL 300
QGW +++A+
Sbjct 594 DTGQGWLYSRAV 605
>gi|290960135|ref|YP_003491317.1| diguanylate cyclase [Streptomyces scabiei 87.22]
gi|260649661|emb|CBG72776.1| putative diguanylate cyclase [Streptomyces scabiei 87.22]
Length=633
Score = 211 bits (538), Expect = 1e-52, Method: Compositional matrix adjust.
Identities = 115/270 (43%), Positives = 159/270 (59%), Gaps = 22/270 (8%)
Query 53 TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAE 112
TR LS+++R A+ RGEF L YQP++ +A+ + G EAL+RW HP G L P RFI AE
Sbjct 347 TRQALSSTLRAAVGRGEFVLEYQPLVGMAEGEVRGVEALVRWHHPQFGLLTPNRFISLAE 406
Query 113 NNGLMVPLTAFVLEQACRHVRSWRDHSTDPQP-FVSVNVSASTICDPGFLVLVEGVLGET 171
+G +V L ++L ACR R W+ D P FVSVNV+ + D + V +L ET
Sbjct 407 EDGSIVQLGRWILATACRQARRWQTDHPDRAPIFVSVNVAVRQVWDSDLVADVAEILAET 466
Query 172 GLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVV 231
GL H LQLEL E A + + + L+ LS +GV IAIDDFG G+S+LAYL RLPV V+
Sbjct 467 GLAPHLLQLELTESALMGSAGRPLQALRALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVL 526
Query 232 KLGGKFI---------------------ECLDGDIQARLANEQITRAMIDLGDKLGITVT 270
KL G F+ + ++ Q A+E I A++ L +LG++VT
Sbjct 527 KLDGAFVRGFQYEGGEEGAGPGAAGPEADDVEDSGQPSPADEIIVEALVQLAHRLGLSVT 586
Query 271 AKLVETPSQAARLRAFGCKAAQGWHFAKAL 300
A+ VET +QA+RLR GC QGW +++A+
Sbjct 587 AEGVETDAQASRLRRLGCDTGQGWLYSRAV 616
>gi|302865940|ref|YP_003834577.1| diguanylate cyclase [Micromonospora aurantiaca ATCC 27029]
gi|302568799|gb|ADL45001.1| diguanylate cyclase [Micromonospora aurantiaca ATCC 27029]
Length=716
Score = 211 bits (537), Expect = 1e-52, Method: Compositional matrix adjust.
Identities = 116/244 (48%), Positives = 148/244 (61%), Gaps = 3/244 (1%)
Query 66 DRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVL 125
DRGEF L YQPI+ L D ++ EAL+RW+HP LG + P RFI AE GL+V L A+VL
Sbjct 468 DRGEFVLHYQPIVSLLDGTMVAVEALVRWQHPELGLIGPDRFIGLAEETGLIVRLGAWVL 527
Query 126 EQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAED 185
QACR SWR D P VSVN++A DP + V L TGLPA LQLEL E
Sbjct 528 RQACRDAESWRRAYPDTTPVVSVNLAARQADDPAIVETVAEALQHTGLPAELLQLELTES 587
Query 186 ARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDI 245
A + + + L +L+ LG+ +AIDDFG G+S+LAYL RLP+ VKL G F+E + GD
Sbjct 588 AVMGSAGEPLRTLHQLAGLGLRLAIDDFGTGYSNLAYLRRLPIHCVKLAGPFVEGIRGDG 647
Query 246 QARLA---NEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPV 302
+A +E+I A++ L L ++VTA+ VET QA RLRA C QG F +P
Sbjct 648 GDAVADHRDERIVDALVRLAHALELSVTAEAVETEVQAERLRALRCDTGQGRLFGAPMPA 707
Query 303 DFFR 306
D R
Sbjct 708 DGIR 711
>gi|315502496|ref|YP_004081383.1| diguanylate cyclase/phosphodiesterase with pas/pac sensor(s)
[Micromonospora sp. L5]
gi|315409115|gb|ADU07232.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Micromonospora sp. L5]
Length=716
Score = 211 bits (537), Expect = 1e-52, Method: Compositional matrix adjust.
Identities = 116/244 (48%), Positives = 148/244 (61%), Gaps = 3/244 (1%)
Query 66 DRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVL 125
DRGEF L YQPI+ L D ++ EAL+RW+HP LG + P RFI AE GL+V L A+VL
Sbjct 468 DRGEFVLHYQPIVSLLDGTMVAVEALVRWQHPELGLIGPDRFIGLAEETGLIVRLGAWVL 527
Query 126 EQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAED 185
QACR SWR D P VSVN++A DP + V L TGLPA LQLEL E
Sbjct 528 RQACRDAESWRRAYPDTTPVVSVNLAARQADDPAIVETVAEALQHTGLPAELLQLELTES 587
Query 186 ARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDI 245
A + + + L +L+ LG+ +AIDDFG G+S+LAYL RLP+ VKL G F+E + GD
Sbjct 588 AVMGSAGEPLRTLHQLAGLGLRLAIDDFGTGYSNLAYLRRLPIHCVKLAGPFVEGIRGDG 647
Query 246 QARLA---NEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPV 302
+A +E+I A++ L L ++VTA+ VET QA RLRA C QG F +P
Sbjct 648 GDAVADHRDERIVDALVRLAHALELSVTAEAVETEVQAERLRALRCDTGQGRLFGAPMPA 707
Query 303 DFFR 306
D R
Sbjct 708 DGIR 711
>gi|329938501|ref|ZP_08287926.1| sensory box/GGDEF family protein [Streptomyces griseoaurantiacus
M045]
gi|329302474|gb|EGG46365.1| sensory box/GGDEF family protein [Streptomyces griseoaurantiacus
M045]
Length=715
Score = 209 bits (533), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 118/278 (43%), Positives = 168/278 (61%), Gaps = 3/278 (1%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A++ N + AD + D + TRH L+T++ ALDRGEFF+ YQP++RL D + GAEA
Sbjct 431 RAKSAGGNRYELADPEADARAITRHGLTTALPAALDRGEFFIEYQPLVRLDDGEVHGAEA 490
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSW-RDHSTDPQPFVSVN 149
L+RW HP G L P RFI AE+ GL+VPL +VLE++ R R W R H D V+VN
Sbjct 491 LVRWLHPQHGVLGPDRFIGLAEHTGLIVPLGRWVLEESVRQARDWQRQHGEDFPLRVNVN 550
Query 150 VSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIA 209
+S + PG + +L TG+ AL LE+ E A + D+ + L+ L+ +GV IA
Sbjct 551 LSPCQLTHPGLVSDTVEILERTGVEPEALCLEVTESALIGADDDLLKPLRRLAEMGVDIA 610
Query 210 IDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITV 269
+DDFG G+S+LA L RLPV ++KL F + + A + +I ++ L L +TV
Sbjct 611 LDDFGTGYSNLANLRRLPVSILKLDRSFTQGMQ-QYPADPVDLKIVEGIVTLAHSLDLTV 669
Query 270 TAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
T + VET +QA +LR GC AQGW++A+ P D RE
Sbjct 670 TVEGVETGAQAEQLRVLGCDTAQGWYYARPGPPDRLRE 707
>gi|324998105|ref|ZP_08119217.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Pseudonocardia sp. P1]
Length=737
Score = 209 bits (532), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 122/261 (47%), Positives = 148/261 (57%), Gaps = 8/261 (3%)
Query 49 DQVNTRH-----YLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLL 103
DQ RH L+ M ALDRGEF L YQP++ +D R+ G EAL RW L
Sbjct 455 DQARHRHDVHLFELAGRMPGALDRGEFDLEYQPLVSFSDGRVAGVEALARWRTADGDRLG 514
Query 104 PGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVL 163
P FI AE GL+VPL +L +AC R+W D + +SVNV+ + P +
Sbjct 515 PDVFIPLAEQTGLIVPLGLHLLHRACSDARAWVDADPSREFVLSVNVAGRQLRQPDAVQR 574
Query 164 VEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYL 223
+ GVL TG PAHALQLEL E +S + V LQELS LGV IAIDDFG G+S+L YL
Sbjct 575 IAGVLERTGWPAHALQLELTESDLMSASGRPVAALQELSRLGVRIAIDDFGTGYSNLVYL 634
Query 224 PRLPVDVVKLGGKFIECLD---GDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQA 280
RLPVDV+KL G F+ D D + + I AMIDL LG+ V A+ VET QA
Sbjct 635 HRLPVDVLKLAGSFVSAQDPQAADATREVDSPVILSAMIDLAHSLGLRVVAESVETDGQA 694
Query 281 ARLRAFGCKAAQGWHFAKALP 301
A LR+ GC QGW A LP
Sbjct 695 AHLRSLGCDVGQGWFMAPPLP 715
>gi|288919235|ref|ZP_06413571.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Frankia sp. EUN1f]
gi|288349330|gb|EFC83571.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Frankia sp. EUN1f]
Length=703
Score = 207 bits (527), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 120/268 (45%), Positives = 157/268 (59%), Gaps = 9/268 (3%)
Query 41 DQWADSDRDQVN---TRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHP 97
+QW D D+ TR LS SM L RGEF L YQPI+ L D + GAEALLRW+HP
Sbjct 430 NQWTAFDPDRGTREATRGLLSRSMSPGLARGEFSLAYQPIVDLRDATMAGAEALLRWDHP 489
Query 98 TLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICD 157
LG PG FID AE++G +V L +VLE+AC R W H FVSVN+S + +
Sbjct 490 HLGPTRPGEFIDLAEDSGFIVELGQWVLERACEVARDWPAHM-----FVSVNLSGRQLRE 544
Query 158 PGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGF 217
PG + +VE +L TGLPA LQLEL E + + V L EL+ALGV I IDDFG G+
Sbjct 545 PGLVKVVERILARTGLPAQRLQLELTESVLMDSGGRQVGALHELNALGVRIVIDDFGTGW 604
Query 218 SSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETP 277
S+ AYL +PV +KL G F+ L + ++ + A+++ KL ++VTA+ +ET
Sbjct 605 SNFAYLSTMPVRGLKLAGLFVAKLGKGTEPS-RDDHLVEAIVEFARKLRLSVTAEGIETS 663
Query 278 SQAARLRAFGCKAAQGWHFAKALPVDFF 305
QAA LRAFG QG F + + F
Sbjct 664 EQAAALRAFGADLGQGHLFGEPVSAGEF 691
>gi|295835411|ref|ZP_06822344.1| sensory box/GGDEF family protein [Streptomyces sp. SPB74]
gi|197696504|gb|EDY43437.1| sensory box/GGDEF family protein [Streptomyces sp. SPB74]
Length=716
Score = 206 bits (525), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 117/278 (43%), Positives = 167/278 (61%), Gaps = 3/278 (1%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A+A N + AD + D + TRH L+TS+ AL+RGEFF+ YQP++ L D + GAEA
Sbjct 431 RAKAAGGNRYEVADPEADARAITRHGLTTSLPAALERGEFFIEYQPLVDLGDGTVHGAEA 490
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPF-VSVN 149
L+RW HP GT+ P RFI AE+ GL+VPL +VL+Q+ R R W++ P P V+VN
Sbjct 491 LVRWSHPQHGTIGPDRFIPLAEHTGLIVPLGRWVLDQSARQARLWQEEHGGPAPLRVNVN 550
Query 150 VSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIA 209
+S + P + +L TGLP AL LE+ E A + D+ + L+ L+ +GV IA
Sbjct 551 LSPCQLQHPRLVADTVEILERTGLPPGALCLEVTESALIGADDDLLKPLRRLAEMGVDIA 610
Query 210 IDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITV 269
+DDFG G+S+LA L RLPV V+KL F + + A + +I ++ L L + V
Sbjct 611 LDDFGTGYSNLANLRRLPVSVLKLDRAFTQGMQ-QFPADPVDLKIVEGIVALAHSLDLAV 669
Query 270 TAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
T + VET +QA +LR GC AQGW++A+ P RE
Sbjct 670 TVEGVETSAQADQLRELGCDTAQGWYYARPGPAARVRE 707
>gi|331694322|ref|YP_004330561.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase
[Pseudonocardia dioxanivorans CB1190]
gi|326949011|gb|AEA22708.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Pseudonocardia dioxanivorans CB1190]
Length=734
Score = 206 bits (524), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 128/308 (42%), Positives = 171/308 (56%), Gaps = 12/308 (3%)
Query 2 DRCCQRATAFACALRPTKLIDYEEMFRGA----MQARAMVANPDQWADSDRDQVNT-RHY 56
+R + + PT EE+ R A ARA D +RD R
Sbjct 418 ERSLTVTASIGVSEAPTATTVPEELMRAADVALSWARAQGGGRRVAYDPERDAGEAARFT 477
Query 57 LSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGL 116
L + A++RGEF L +QP++RLA R+ G EAL+RW+HP G L PGRFI+ AE +G
Sbjct 478 LLAGLPEAVERGEFRLAFQPLVRLASGRLCGTEALVRWQHPVEGLLGPGRFIELAERSGA 537
Query 117 MVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAH 176
+V L +VL +ACR +W + P+VSVNVS + PG+L V +L E+GLPA
Sbjct 538 IVALGDWVLGEACRQAAAWYAELGEQSPYVSVNVSPVQLVAPGWLAGVRKMLAESGLPAE 597
Query 177 ALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGK 236
LQLE+ E A L + A+ L L + GV +A+DDFG G+SSLA+L RLPV +K+ G
Sbjct 598 KLQLEITEQAVLGDEAVALDVLGALRSEGVRLALDDFGTGWSSLAWLRRLPVHALKIDGS 657
Query 237 FIECL---DGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQG 293
FI+ L D D +E I RA+++L LG+ VTA+ VET QA RL GC QG
Sbjct 658 FIDGLRHPDPDPM----DESIVRALVELAHALGLEVTAEWVETRVQAERLERLGCDLGQG 713
Query 294 WHFAKALP 301
F A P
Sbjct 714 RWFGDAGP 721
>gi|302523204|ref|ZP_07275546.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces sp. SPB78]
gi|318061390|ref|ZP_07980111.1| hypothetical protein SSA3_25836 [Streptomyces sp. SA3_actG]
gi|318078186|ref|ZP_07985518.1| hypothetical protein SSA3_16060 [Streptomyces sp. SA3_actF]
gi|302432099|gb|EFL03915.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)
[Streptomyces sp. SPB78]
Length=719
Score = 205 bits (521), Expect = 9e-51, Method: Compositional matrix adjust.
Identities = 116/278 (42%), Positives = 166/278 (60%), Gaps = 3/278 (1%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A+A N + AD + D + TRH L+T++ AL+RGEFF+ YQP++ L D + GAEA
Sbjct 434 RAKAAGGNRYEVADPEADARAITRHGLTTALPAALERGEFFIEYQPLVDLGDGTVHGAEA 493
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPF-VSVN 149
L+RW HP GT+ P RFI AE+ GL+VPL +VL+++ R R W++ P P V+VN
Sbjct 494 LVRWSHPQHGTISPDRFIPLAEHTGLIVPLGRWVLDESARQARLWQEERGGPAPLRVNVN 553
Query 150 VSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIA 209
+S + P + +L TGLP AL LE+ E A + DE + L+ L+ +GV IA
Sbjct 554 LSPCQLQHPRLVADTVEILERTGLPPGALCLEVTESALIGADEDLLKPLRRLAEMGVDIA 613
Query 210 IDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITV 269
+DDFG G+S+LA L RLPV V+KL F + A + +I ++ L L + V
Sbjct 614 LDDFGTGYSNLANLRRLPVSVLKLDRAFTRGMQ-QFPADPVDLKIVEGIVALAHSLDLAV 672
Query 270 TAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
T + VET +QA +LR GC AQGW++A+ P RE
Sbjct 673 TVEGVETSAQADQLRELGCDTAQGWYYARPGPAARVRE 710
>gi|117165116|emb|CAJ88670.1| conserved hypothetical protein [Streptomyces ambofaciens ATCC
23877]
Length=714
Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 117/281 (42%), Positives = 169/281 (61%), Gaps = 6/281 (2%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A++ N + AD + D +V TRH L+T++ AL+RGEFF+ YQP++ L D + GAEA
Sbjct 427 RAKSAGGNRYELADPEADARVITRHGLTTALPAALERGEFFIEYQPLVHLGDGSVHGAEA 486
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRD---HSTDPQPF-V 146
L+RW HP G L P RFI AE+ GL+VPL +VLEQ+ R R WR+ ST P +
Sbjct 487 LVRWLHPQHGVLGPDRFIPLAEHTGLIVPLGRWVLEQSVRQARVWRERYGESTAAGPLRI 546
Query 147 SVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGV 206
+VN+S + PG + +L TG+ AL LE+ E A + D+ + L+ L+ +GV
Sbjct 547 NVNLSPCQLTHPGLVQDTVDILERTGVAPDALCLEVTESALIGADDDLLKPLRRLAEMGV 606
Query 207 GIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLG 266
IA+DDFG G+S+LA L RLPV V+KL F + + A + +I ++ L L
Sbjct 607 DIALDDFGTGYSNLANLRRLPVSVLKLDRSFTQSMQ-RFPADPVDLKIVEGIVALAHSLD 665
Query 267 ITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
+TVT + VET +QA +LR GC AQGW++A+ P + E
Sbjct 666 LTVTVEGVETGAQAEQLRILGCDTAQGWYYARPGPPERLHE 706
>gi|302538187|ref|ZP_07290529.1| conserved hypothetical protein [Streptomyces sp. C]
gi|302447082|gb|EFL18898.1| conserved hypothetical protein [Streptomyces sp. C]
Length=529
Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 113/268 (43%), Positives = 166/268 (62%), Gaps = 2/268 (0%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A+A N ++AD++ D + TRH L+ ++ AL+RGEFF+ YQP++ + D + GAEA
Sbjct 244 RAKAAGGNRFEFADAEADARAITRHGLTNALPAALERGEFFIEYQPLVHMHDGSVHGAEA 303
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNV 150
L+RW HP G L P RFI AE GL+VPL +VLE++ R R+W+ V+VN+
Sbjct 304 LVRWSHPQYGVLGPDRFIPLAERTGLIVPLGRWVLEESVRQARTWQRQHGGAALRVNVNL 363
Query 151 SASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAI 210
S + + PG + VL +GL AL LE+ E A + D++ + L+ L+ALGV IA+
Sbjct 364 SPTQLHHPGLVADTVRVLEASGLAPGALCLEVTESALIGADDELLEPLRRLAALGVDIAL 423
Query 211 DDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVT 270
DDFG G+S+LA L RLPV V+KL F + + A + +I ++ L L + VT
Sbjct 424 DDFGTGYSNLANLRRLPVSVLKLDRSFTQGMQ-QQPADPVDVKIVEGIVSLAHSLELAVT 482
Query 271 AKLVETPSQAARLRAFGCKAAQGWHFAK 298
+ VET +QAA+LRA GC AQGW++A+
Sbjct 483 VEGVETGAQAAQLRALGCDTAQGWYYAR 510
>gi|254383498|ref|ZP_04998849.1| conserved hypothetical protein [Streptomyces sp. Mg1]
gi|194342394|gb|EDX23360.1| conserved hypothetical protein [Streptomyces sp. Mg1]
Length=709
Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 114/268 (43%), Positives = 165/268 (62%), Gaps = 2/268 (0%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A+A N ++AD++ D + TRH L+ ++ AL+RGEFF+ YQP++ L D + GAEA
Sbjct 424 RAKAAGGNRFEFADAEADARAITRHGLTNALPAALERGEFFIEYQPLVHLHDGSVHGAEA 483
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNV 150
L+RW HP G L P RFI AE GL+VPL +VLE+A R R+W+ V+VN+
Sbjct 484 LVRWSHPQYGVLGPDRFIPLAERTGLIVPLGRWVLEEAVRQARNWQRQHGCSALRVNVNL 543
Query 151 SASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAI 210
S + + PG + VL +GL AL LE+ E A + D++ + L+ L+ALGV IA+
Sbjct 544 SPTQLHHPGLVADTVAVLENSGLAPGALCLEVTESALIGADDELLEPLRRLAALGVDIAL 603
Query 211 DDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVT 270
DDFG G+S+LA L RLPV V+KL F + + A + +I ++ L L + VT
Sbjct 604 DDFGTGYSNLANLRRLPVSVLKLDRSFTQGMQQQ-PADPVDVKIVEGIVALAHSLELAVT 662
Query 271 AKLVETPSQAARLRAFGCKAAQGWHFAK 298
+ VET +QAA+LR GC AQGW++A+
Sbjct 663 VEGVETGAQAAQLRELGCDTAQGWYYAR 690
>gi|290955706|ref|YP_003486888.1| hypothetical protein SCAB_11501 [Streptomyces scabiei 87.22]
gi|260645232|emb|CBG68318.1| conserved hypothetical protein [Streptomyces scabiei 87.22]
Length=714
Score = 203 bits (517), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 117/281 (42%), Positives = 167/281 (60%), Gaps = 6/281 (2%)
Query 32 QARAMVANPDQWADSDRD-QVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEA 90
+A++ N + AD++ D + TRH L+T++ ALDRGEFF+ YQP++ L D + GAEA
Sbjct 427 RAKSAGGNRYEVADAEADARAITRHGLTTALPAALDRGEFFIEYQPLVHLGDGTVRGAEA 486
Query 91 LLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQ---PF-V 146
L+RW HP G L P RFI AE GL+VPL +VLEQ+ R R+W++ + P V
Sbjct 487 LVRWLHPQHGVLGPDRFIPLAERTGLIVPLGRWVLEQSVRQARAWQERGGGTRAAGPLRV 546
Query 147 SVNVSASTICDPGFLVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGV 206
+VN+S + PG + +L GLP AL LE+ E A + D+ + L+ LS +GV
Sbjct 547 NVNLSPCQLTHPGLVQDTVDILERAGLPPDALCLEVTESALIGADDDLLKPLRRLSEMGV 606
Query 207 GIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLG 266
IA+DDFG G+S+LA L RLPV V+KL F + + A + +I ++ L L
Sbjct 607 DIALDDFGTGYSNLANLRRLPVRVLKLDRSFTQSMQ-RFPADPVDLKIVEGIVSLAHSLD 665
Query 267 ITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE 307
+ VT + VET +QA +LR GC AQGW++A+ P D E
Sbjct 666 LAVTVEGVETGAQAEQLRILGCDTAQGWYYARPGPPDRLHE 706
Lambda K H
0.324 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 521296303248
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40