BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1377c
Length=212
Score E
Sequences producing significant alignments: (Bits) Value
gi|15840835|ref|NP_335872.1| hypothetical protein MT1421 [Mycoba... 435 2e-120
gi|15608517|ref|NP_215893.1| putative transferase [Mycobacterium... 434 4e-120
gi|340626391|ref|YP_004744843.1| putative transferase [Mycobacte... 432 2e-119
gi|296170757|ref|ZP_06852329.1| thiopurine S-methyltransferase f... 361 4e-98
gi|240170754|ref|ZP_04749413.1| hypothetical protein MkanA1_1568... 360 8e-98
gi|183982206|ref|YP_001850497.1| NodS-like (sam)-dependent methy... 323 1e-86
gi|118472427|ref|YP_887357.1| thiopurine S-methyltransferase (tp... 270 1e-70
gi|294994882|ref|ZP_06800573.1| hypothetical protein Mtub2_10319... 254 9e-66
gi|289569392|ref|ZP_06449619.1| transferase [Mycobacterium tuber... 210 1e-52
gi|302525631|ref|ZP_07277973.1| predicted protein [Streptomyces ... 177 7e-43
gi|300784405|ref|YP_003764696.1| transferase [Amycolatopsis medi... 174 9e-42
gi|291301387|ref|YP_003512665.1| type 11 methyltransferase [Stac... 161 5e-38
gi|268322269|emb|CBH32791.1| putative dehydrogenase [Streptomyce... 157 1e-36
gi|169627967|ref|YP_001701616.1| hypothetical protein MAB_0868c ... 154 1e-35
gi|342858454|ref|ZP_08715109.1| hypothetical protein MCOL_06251 ... 140 1e-31
gi|41408894|ref|NP_961730.1| hypothetical protein MAP2796c [Myco... 139 2e-31
gi|169627966|ref|YP_001701615.1| putative transferase [Mycobacte... 139 2e-31
gi|110611756|dbj|BAE98167.1| putative SAM-dependent methyltransf... 139 2e-31
gi|254776010|ref|ZP_05217526.1| hypothetical protein MaviaA2_152... 139 2e-31
gi|118463475|ref|YP_882748.1| thiopurine S-methyltransferase (tp... 139 3e-31
gi|219565266|dbj|BAH04163.1| putative SAM-dependent methyltransf... 139 3e-31
gi|266631104|emb|CBH32104.1| putative dehydrogenase and domain w... 139 3e-31
gi|254818552|ref|ZP_05223553.1| hypothetical protein MintA_01441... 137 9e-31
gi|296171937|ref|ZP_06852982.1| thiopurine S-methyltransferase (... 136 2e-30
gi|226362772|ref|YP_002780550.1| hypothetical protein ROP_33580 ... 136 3e-30
gi|41406223|ref|NP_959059.1| hypothetical protein MAP0125c [Myco... 130 1e-28
gi|336458089|gb|EGO37075.1| Thiopurine S-methyltransferase (TPMT... 130 1e-28
gi|312137777|ref|YP_004005113.1| SAM dependent methyltransferase... 130 2e-28
gi|254773164|ref|ZP_05214680.1| thiopurine S-methyltransferase (... 129 4e-28
gi|118465195|ref|YP_879415.1| thiopurine S-methyltransferase (tp... 129 4e-28
gi|169629918|ref|YP_001703567.1| hypothetical protein MAB_2834c ... 128 7e-28
gi|325675063|ref|ZP_08154749.1| thiopurine S-methyltransferase f... 127 7e-28
gi|118468119|ref|YP_886428.1| methyltransferase type 12 [Mycobac... 127 1e-27
gi|120402886|ref|YP_952715.1| type 11 methyltransferase [Mycobac... 127 1e-27
gi|220915318|ref|YP_002490622.1| type 11 methyltransferase [Anae... 126 2e-27
gi|197120607|ref|YP_002132558.1| type 11 methyltransferase [Anae... 126 2e-27
gi|289570849|ref|ZP_06451076.1| conserved hypothetical protein [... 125 3e-27
gi|118618639|ref|YP_906971.1| methyltransferase [Mycobacterium u... 124 7e-27
gi|183982054|ref|YP_001850345.1| methyltransferase [Mycobacteriu... 124 8e-27
gi|15609812|ref|NP_217191.1| hypothetical protein Rv2675c [Mycob... 124 1e-26
gi|169627497|ref|YP_001701146.1| methyltransferase [Mycobacteriu... 124 1e-26
gi|254365337|ref|ZP_04981382.1| conserved hypothetical protein [... 124 1e-26
gi|288916265|ref|ZP_06410644.1| Methyltransferase type 11 [Frank... 124 1e-26
gi|296168231|ref|ZP_06850204.1| thiopurine S-methyltransferase f... 123 1e-26
gi|254822596|ref|ZP_05227597.1| hypothetical protein MintA_21884... 123 2e-26
gi|240172077|ref|ZP_04750736.1| hypothetical protein MkanA1_2236... 122 3e-26
gi|340625587|ref|YP_004744039.1| putative benzoquinone methyltra... 122 5e-26
gi|111017239|ref|YP_700211.1| hypothetical protein RHA1_ro00217 ... 121 5e-26
gi|298524048|ref|ZP_07011457.1| conserved hypothetical protein [... 120 1e-25
gi|84617327|emb|CAI94687.1| hypothetical protein [Streptomyces a... 120 1e-25
>gi|15840835|ref|NP_335872.1| hypothetical protein MT1421 [Mycobacterium tuberculosis CDC1551]
gi|308231825|ref|ZP_07663943.1| transferase [Mycobacterium tuberculosis SUMu001]
gi|308369784|ref|ZP_07666806.1| transferase [Mycobacterium tuberculosis SUMu002]
19 more sequence titles
Length=226
Score = 435 bits (1119), Expect = 2e-120, Method: Compositional matrix adjust.
Identities = 212/212 (100%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA
Sbjct 15 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 74
Query 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF
Sbjct 75 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 134
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD
Sbjct 135 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 194
Query 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
IESLEPATVRRELDGTEVEMAFWNVRAQRRGS
Sbjct 195 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 226
>gi|15608517|ref|NP_215893.1| putative transferase [Mycobacterium tuberculosis H37Rv]
gi|31792571|ref|NP_855064.1| putative transferase [Mycobacterium bovis AF2122/97]
gi|121637307|ref|YP_977530.1| putative transferase [Mycobacterium bovis BCG str. Pasteur 1173P2]
52 more sequence titles
Length=212
Score = 434 bits (1116), Expect = 4e-120, Method: Compositional matrix adjust.
Identities = 212/212 (100%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA
Sbjct 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
Query 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF
Sbjct 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD
Sbjct 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
Query 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
IESLEPATVRRELDGTEVEMAFWNVRAQRRGS
Sbjct 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
>gi|340626391|ref|YP_004744843.1| putative transferase [Mycobacterium canettii CIPT 140010059]
gi|340004581|emb|CCC43725.1| putative transferase [Mycobacterium canettii CIPT 140010059]
Length=212
Score = 432 bits (1110), Expect = 2e-119, Method: Compositional matrix adjust.
Identities = 211/212 (99%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA
Sbjct 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
Query 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF
Sbjct 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
HCLDDDGKRSYAASVHRATRPGATLLLSCFS+AMPPDEEWPRSTVSEQTLRDVLGGAGWD
Sbjct 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSDAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
Query 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
IESLEPATVRRELDGTEVEMAFWNVRAQRRGS
Sbjct 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
>gi|296170757|ref|ZP_06852329.1| thiopurine S-methyltransferase family protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295894572|gb|EFG74309.1| thiopurine S-methyltransferase family protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=225
Score = 361 bits (926), Expect = 4e-98, Method: Compositional matrix adjust.
Identities = 170/207 (83%), Positives = 189/207 (92%), Gaps = 0/207 (0%)
Query 4 IDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
+DFDALYRGESPGEG+PP+ TPPWDTKAPKD+V+ WH GGWVHGDVLDIGCGLGDNAIYL
Sbjct 19 MDFDALYRGESPGEGIPPMATPPWDTKAPKDSVVAWHGGGWVHGDVLDIGCGLGDNAIYL 78
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL 123
ARNG++VTGLDIS TAL TA+RRA +AG DV FAV DATKL G+T AFDTVID GMFHCL
Sbjct 79 ARNGFRVTGLDISATALVTAQRRAHEAGADVTFAVADATKLEGFTDAFDTVIDSGMFHCL 138
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
DDDGKRSYAA+VHRATRPGATLL+SCFS+A PDE WPR +VSEQTLRDVLGGA WDIES
Sbjct 139 DDDGKRSYAAAVHRATRPGATLLISCFSDANGPDERWPRPSVSEQTLRDVLGGAAWDIES 198
Query 184 LEPATVRRELDGTEVEMAFWNVRAQRR 210
LEPAT+RRE+DG +VEMAFW+VRA+RR
Sbjct 199 LEPATMRREVDGAQVEMAFWSVRARRR 225
>gi|240170754|ref|ZP_04749413.1| hypothetical protein MkanA1_15682 [Mycobacterium kansasii ATCC
12478]
Length=239
Score = 360 bits (924), Expect = 8e-98, Method: Compositional matrix adjust.
Identities = 168/211 (80%), Positives = 189/211 (90%), Gaps = 0/211 (0%)
Query 2 PGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAI 61
P +DFDALYRGESPG G+PP+TTPPWDTKAPK+NVI W TGGWVHG+VLDIGCG GDNAI
Sbjct 28 PRMDFDALYRGESPGPGIPPMTTPPWDTKAPKENVIAWQTGGWVHGEVLDIGCGFGDNAI 87
Query 62 YLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFH 121
YLA++G++VT +DISPTAL TA+RRA+DAGVDV+FA DAT L GYT FDTVID GMFH
Sbjct 88 YLAQHGHRVTAMDISPTALITAERRAADAGVDVRFAAADATTLDGYTDRFDTVIDSGMFH 147
Query 122 CLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
CLDDDGKRSYAA+VHRATRPGATLL+SCFS+A PP+E+WPR VSEQTLRDVLGGA WD+
Sbjct 148 CLDDDGKRSYAAAVHRATRPGATLLISCFSDANPPNEQWPRPAVSEQTLRDVLGGAAWDV 207
Query 182 ESLEPATVRRELDGTEVEMAFWNVRAQRRGS 212
ESLEP TVRRE+DGTE EM+FW VRAQRR S
Sbjct 208 ESLEPVTVRREMDGTETEMSFWYVRAQRRTS 238
>gi|183982206|ref|YP_001850497.1| NodS-like (sam)-dependent methyltransferase [Mycobacterium marinum
M]
gi|183175532|gb|ACC40642.1| NodS-like (sam)-dependent methyltransferase [Mycobacterium marinum
M]
Length=211
Score = 323 bits (827), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 157/210 (75%), Positives = 178/210 (85%), Gaps = 3/210 (1%)
Query 4 IDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
+DFDALYRGESP G+ P+TTPPWDTKAPK+NVI W GGWVHGDVLDIGCGLGDNAIYL
Sbjct 1 MDFDALYRGESPRPGVAPMTTPPWDTKAPKENVIAWQAGGWVHGDVLDIGCGLGDNAIYL 60
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL 123
A +G+ VTGLDISPTAL TA RRA DAGV V FAV DATKL GYT AFDTVID GMFHCL
Sbjct 61 AAHGHPVTGLDISPTALITAARRADDAGVHVTFAVADATKLDGYTDAFDTVIDSGMFHCL 120
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
DD+GKRSYAA+VHRATRPGATLL+SCF +A PP+E+ PR V EQTLRDVLGGAGW+I +
Sbjct 121 DDEGKRSYAAAVHRATRPGATLLMSCFCDANPPNEQQPRPAVPEQTLRDVLGGAGWEIAA 180
Query 184 LEPATVRREL---DGTEVEMAFWNVRAQRR 210
L+P TV R+L DG +++AFW VRA+R+
Sbjct 181 LDPVTVNRQLGGSDGQPIKLAFWYVRARRQ 210
>gi|118472427|ref|YP_887357.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
smegmatis str. MC2 155]
gi|118173714|gb|ABK74610.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
smegmatis str. MC2 155]
Length=225
Score = 270 bits (690), Expect = 1e-70, Method: Compositional matrix adjust.
Identities = 138/217 (64%), Positives = 156/217 (72%), Gaps = 10/217 (4%)
Query 4 IDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
DFDALYRGESP EG+PPIT+ PWDTKAPK+NV+ W G VHG VLDIGCGLGDNAIYL
Sbjct 9 FDFDALYRGESPAEGVPPITSVPWDTKAPKENVVAWEQAGLVHGHVLDIGCGLGDNAIYL 68
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL 123
A+ GY+VT LDISPTAL TA+RRA+DAGVDV FAV DAT+L GY FDTV+D GMFHCL
Sbjct 69 AQQGYRVTALDISPTALITAERRAADAGVDVTFAVADATRLDGYDDVFDTVVDSGMFHCL 128
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
DD K SYAA+VHRATR GATLLL FS+A + W + VSE TLR L GWDI S
Sbjct 129 SDDAKGSYAAAVHRATRAGATLLLGAFSDANLQHDNWQAAWVSEDTLRSSLDDGGWDITS 188
Query 184 LEPATVR----------RELDGTEVEMAFWNVRAQRR 210
L T+R E E + AF+ V+AQRR
Sbjct 189 LTTETIRVPGAALAGSGDEGGADEFDAAFFLVQAQRR 225
>gi|294994882|ref|ZP_06800573.1| hypothetical protein Mtub2_10319 [Mycobacterium tuberculosis
210]
Length=123
Score = 254 bits (648), Expect = 9e-66, Method: Compositional matrix adjust.
Identities = 123/123 (100%), Positives = 123/123 (100%), Gaps = 0/123 (0%)
Query 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA
Sbjct 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
Query 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF
Sbjct 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMF 120
Query 121 HCL 123
HCL
Sbjct 121 HCL 123
>gi|289569392|ref|ZP_06449619.1| transferase [Mycobacterium tuberculosis T17]
gi|289543146|gb|EFD46794.1| transferase [Mycobacterium tuberculosis T17]
Length=114
Score = 210 bits (534), Expect = 1e-52, Method: Compositional matrix adjust.
Identities = 102/103 (99%), Positives = 103/103 (100%), Gaps = 0/103 (0%)
Query 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA
Sbjct 1 MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNA 60
Query 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATK 103
IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDAT+
Sbjct 61 IYLARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATQ 103
>gi|302525631|ref|ZP_07277973.1| predicted protein [Streptomyces sp. AA4]
gi|302434526|gb|EFL06342.1| predicted protein [Streptomyces sp. AA4]
Length=234
Score = 177 bits (450), Expect = 7e-43, Method: Compositional matrix adjust.
Identities = 88/186 (48%), Positives = 126/186 (68%), Gaps = 9/186 (4%)
Query 4 IDFDALYRGESP-GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIY 62
+DF+ +Y+G++P GE +P WD P+ V+ G HG+VLDIGCGLG+NA+Y
Sbjct 6 VDFEEMYQGKTPIGEKIP------WDIAGPQPAVVALEADGGFHGEVLDIGCGLGENAMY 59
Query 63 LARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
LA G++VTGLD +PTAL A+ A+ G+DV FA DAT+L GY G FD V+D ++HC
Sbjct 60 LASRGHRVTGLDGAPTALARARETAAKRGLDVTFAQADATRLEGYEGRFDAVLDSALYHC 119
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIE 182
LD++ + +Y A++ RAT+PGA L + CFS+A+P + P ++EQ LR+ +G GW I
Sbjct 120 LDEEERHAYVAALGRATKPGAQLNIFCFSDAVPENFPIPYR-ITEQNLRETVGN-GWTIT 177
Query 183 SLEPAT 188
+LEPA
Sbjct 178 ALEPAV 183
>gi|300784405|ref|YP_003764696.1| transferase [Amycolatopsis mediterranei U32]
gi|299793919|gb|ADJ44294.1| putative transferase [Amycolatopsis mediterranei U32]
gi|340525826|gb|AEK41031.1| transferase [Amycolatopsis mediterranei S699]
Length=231
Score = 174 bits (440), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 92/199 (47%), Positives = 126/199 (64%), Gaps = 9/199 (4%)
Query 4 IDFDALYRGESP-GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIY 62
+DF+ LY+G +P G +P WD AP+ V+ G G+VLDIGCGLGDN+ +
Sbjct 6 VDFEELYQGATPMGRKMP------WDLGAPQPAVVALADAGEFTGEVLDIGCGLGDNSAF 59
Query 63 LARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
LA G +VTGLD +P+AL A+ RA++ G+D++FAV DATKL GY G FDTV+D ++HC
Sbjct 60 LASRGLRVTGLDGAPSALEQARSRAAEKGLDIEFAVADATKLEGYEGRFDTVLDSALYHC 119
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIE 182
L +D + +Y A++ RATRPGATL L CFS +P P +SE LR+ + G W IE
Sbjct 120 LAEDERHAYLAALTRATRPGATLHLFCFSEEVPDAFPAP-YLISEANLRETV-GKDWTIE 177
Query 183 SLEPATVRRELDGTEVEMA 201
LEPA + E+ +
Sbjct 178 RLEPAVYTTSMTAEELRQS 196
>gi|291301387|ref|YP_003512665.1| type 11 methyltransferase [Stackebrandtia nassauensis DSM 44728]
gi|290570607|gb|ADD43572.1| Methyltransferase type 11 [Stackebrandtia nassauensis DSM 44728]
Length=243
Score = 161 bits (408), Expect = 5e-38, Method: Compositional matrix adjust.
Identities = 83/182 (46%), Positives = 117/182 (65%), Gaps = 3/182 (1%)
Query 4 IDFDALYRGESPGEGLPP-ITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIY 62
+DF+++YRG +GLP + PWD P+ ++ G V G VLD+GCGLG+NA++
Sbjct 13 VDFESVYRGGPLIDGLPEGAPSTPWDIGEPQPVLVAVEAAGQVRGTVLDVGCGLGENALF 72
Query 63 LARNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
LA GY+VTG+DISPTAL A++RA+D GV+V F VGDAT+L G FDTVID +FHC
Sbjct 73 LAGRGYRVTGVDISPTALEQARQRAADKGVEVDFVVGDATRLAGLDARFDTVIDSALFHC 132
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIE 182
L + + Y A++HR PG T+ + C +++ P P ++E+ LRD G GW I+
Sbjct 133 LKPELRNDYLAALHRVCVPGGTVHMFCGTDSGPAGMPVP-FPINEEVLRDAF-GTGWRID 190
Query 183 SL 184
L
Sbjct 191 EL 192
>gi|268322269|emb|CBH32791.1| putative dehydrogenase [Streptomyces sp. C23201NS3]
Length=776
Score = 157 bits (396), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 84/194 (44%), Positives = 121/194 (63%), Gaps = 7/194 (3%)
Query 5 DFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLA 64
DF ++Y+G+ + PP+ PWD P+ ++ H G + GDVLD+GCGLGDNA +LA
Sbjct 548 DFVSMYQGD---QDAPPVQ--PWDIGRPQPALVDAHKAGLITGDVLDVGCGLGDNAAFLA 602
Query 65 RNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLD 124
G++VT +D+S A+ A RAS GV+V+FAV DAT+LTG+ G FDTV+D +H L
Sbjct 603 SQGHRVTAVDVSQIAVDEASARASAKGVEVEFAVTDATRLTGFDGRFDTVVDSACYHSLA 662
Query 125 DDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESL 184
+D + Y ++HRA RPGA L + F+ +P P S ++LR+V+GG WD+ S+
Sbjct 663 EDDRVRYLEALHRAARPGARLHIFSFAEELPAPFPGPHRH-SARSLREVVGGV-WDVVSV 720
Query 185 EPATVRRELDGTEV 198
E AT L +V
Sbjct 721 EEATYASSLGAADV 734
>gi|169627967|ref|YP_001701616.1| hypothetical protein MAB_0868c [Mycobacterium abscessus ATCC
19977]
gi|169239934|emb|CAM60962.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=262
Score = 154 bits (388), Expect = 1e-35, Method: Compositional matrix adjust.
Identities = 77/179 (44%), Positives = 106/179 (60%), Gaps = 1/179 (0%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+A+Y G+ EG P P WD + + + G + G +LDIGCGLG+N+IYL +
Sbjct 16 FEAVYNGKPMFEGAPAAGVP-WDIRDAQPRIKELAAYGALRGAILDIGCGLGENSIYLTQ 74
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
G VTGLD SP+A+ AK+RA+ AGV V V DATKL G+ FDTVID ++HC D
Sbjct 75 QGLSVTGLDFSPSAIEQAKQRAAAAGVTVDLHVADATKLDGWDAQFDTVIDSAVYHCFDH 134
Query 126 DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESL 184
+G R YA+++HRATRPGA ++CF + P ++ VL A W+I+
Sbjct 135 EGHRQYASALHRATRPGARWFIACFGDGSVNGITMPFGVQDPDEIKSVLSEARWNIQYF 193
>gi|342858454|ref|ZP_08715109.1| hypothetical protein MCOL_06251 [Mycobacterium colombiense CECT
3035]
gi|342134158|gb|EGT87338.1| hypothetical protein MCOL_06251 [Mycobacterium colombiense CECT
3035]
Length=250
Score = 140 bits (352), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 80/196 (41%), Positives = 105/196 (54%), Gaps = 5/196 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEEMYRDQRTSHGLPAAT--PWDIGGPQPVVQQLVALGAIKGEVLDPGTGPGHHAIYYAS 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S TA+ A+ A AGV V F + DATKL G+ G FDTV+DC +H
Sbjct 71 KGYSATGIDGSATAIERARENAQKAGVSVNFELADATKLEGFVGRFDTVVDCAFYHTFST 130
Query 126 DG--KRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +RSY ++HRAT+PGA L + F + RS +SE RDVL GW+I
Sbjct 131 EAELRRSYVDALHRATKPGARLYMFEFGEHNVNGFKMLRS-LSENDFRDVLPEGGWEITY 189
Query 184 LEPATVRRELDGTEVE 199
L T R + +E
Sbjct 190 LGTTTYRVNISAESIE 205
>gi|41408894|ref|NP_961730.1| hypothetical protein MAP2796c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41397253|gb|AAS05113.1| hypothetical protein MAP_2796c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336458825|gb|EGO37782.1| methyltransferase family protein [Mycobacterium avium subsp.
paratuberculosis S397]
Length=250
Score = 139 bits (351), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 81/197 (42%), Positives = 108/197 (55%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G V G+VLD G G G +AIY A
Sbjct 13 FEEMYRDQRTSHGLPAAT--PWDIGGPQPVVRQLVALGAVKGEVLDPGTGPGHHAIYYAS 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL-- 123
G+ TG+D S A+ A+ A AGV V F + DATKL G+ G FDTV+DC +H
Sbjct 71 QGFSATGIDGSAAAIERARANARKAGVSVNFELADATKLDGFDGRFDTVVDCAFYHVFAT 130
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ + + SYA ++HRAT+PGA L + F + RS +SE RDVL AGW+I
Sbjct 131 EPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRS-LSENDFRDVLPAAGWEISY 189
Query 184 LEPATVRRELDGTEVEM 200
L P T + L ++M
Sbjct 190 LGPTTYQVNLSAETIQM 206
>gi|169627966|ref|YP_001701615.1| putative transferase [Mycobacterium abscessus ATCC 19977]
gi|169239933|emb|CAM60961.1| Putative transferase [Mycobacterium abscessus]
Length=235
Score = 139 bits (351), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 89/189 (48%), Positives = 118/189 (63%), Gaps = 13/189 (6%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ LYR +S EG P + PWD+K K + G + GDVLDIGCGLGDNAIYLA+
Sbjct 9 FEDLYR-DSLHEGGPIV---PWDSKDAKPRIKELALLGAIRGDVLDIGCGLGDNAIYLAQ 64
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
G+ VTGLD +P+A+ AK RA+ AGV V F V DAT L G+ FDTVID G++HC D
Sbjct 65 QGFNVTGLDFAPSAIEQAKGRAAAAGVAVDFQVADATTLDGWDARFDTVIDSGVYHCFDA 124
Query 126 DGKRSYAASVHRATRPGATLLLSCFS----NAMP-PDEEWPRSTVSEQTLRDVLGGAGWD 180
+G YA+++HRATRPGA + CF+ + +P P + R+ EQ VL +GW
Sbjct 125 EGHTEYASALHRATRPGARWYIWCFAQGAVHGVPTPFQNGQRAEEIEQ----VLTTSGWS 180
Query 181 IESLEPATV 189
+ + P T+
Sbjct 181 VLQINPTTM 189
>gi|110611756|dbj|BAE98167.1| putative SAM-dependent methyltransferase [Streptomyces lasaliensis]
Length=224
Score = 139 bits (351), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 82/204 (41%), Positives = 110/204 (54%), Gaps = 25/204 (12%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
FDA+YRGESP PPWD AP+ + G + G VLD GCG G++A++LA
Sbjct 5 FDAVYRGESPFG-----KRPPWDIGAPQPAYVALEKAGLIQGAVLDAGCGTGEDALHLAG 59
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY VTGLD+SPTA++ A+ +A G+ F V DA LTG+ FDTVID G+ H +
Sbjct 60 LGYAVTGLDLSPTAISVARDKADARGLGAVFEVADALDLTGWEERFDTVIDSGLAHTFEG 119
Query 126 DGKRSYAASVHRATRPGATLLLSCFSN-------------------AMPPDEEWPRSTVS 166
D R+YA ++HRA RPGA + S+ +P D+E P S
Sbjct 120 DRLRAYATALHRACRPGAVAHILSISDRGSAEMQARLAEAIDEIPAPLPDDDESPTLKRS 179
Query 167 EQTLRDVLGGAGWDIESLEPATVR 190
LRD GW IES++ + +R
Sbjct 180 ADHLRDGF-AEGWTIESIDESLMR 202
>gi|254776010|ref|ZP_05217526.1| hypothetical protein MaviaA2_15260 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=250
Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 80/197 (41%), Positives = 108/197 (55%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEEMYRDQRTSHGLPAAT--PWDIGGPQPVVRQLVALGAIKGEVLDPGTGPGHHAIYYAS 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL-- 123
G+ TG+D S A+ A+ A AGV V F + DATKL G+ G FDTV+DC +H
Sbjct 71 QGFSATGIDGSAAAIERARANAHKAGVSVNFELADATKLDGFDGRFDTVVDCAFYHVFAA 130
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ + + SYA ++HRAT+PGA L + F + RS +SE RDVL AGW+I
Sbjct 131 EPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRS-LSENDFRDVLPAAGWEISY 189
Query 184 LEPATVRRELDGTEVEM 200
L P T + L ++M
Sbjct 190 LGPTTYQVNLSAETIQM 206
>gi|118463475|ref|YP_882748.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
avium 104]
gi|118164762|gb|ABK65659.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
avium 104]
Length=250
Score = 139 bits (350), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 81/197 (42%), Positives = 108/197 (55%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G V G+VLD G G G +AIY A
Sbjct 13 FEEMYRDQRTSHGLPAAT--PWDIGGPQPVVRQLVALGAVKGEVLDPGTGPGHHAIYYAS 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL-- 123
G+ TG+D S A+ A+ A AGV V F + DATKL G+ G FDTV+DC +H
Sbjct 71 QGFSATGIDGSAAAIERARANARTAGVSVNFELADATKLDGFDGRFDTVVDCAFYHVFAT 130
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ + + SYA ++HRAT+PGA L + F + RS +SE RDVL AGW+I
Sbjct 131 EPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRS-LSENDFRDVLPAAGWEISY 189
Query 184 LEPATVRRELDGTEVEM 200
L P T + L ++M
Sbjct 190 LGPTTYQVNLSAETIQM 206
>gi|219565266|dbj|BAH04163.1| putative SAM-dependent methyltransferase [Streptomyces triostinicus]
Length=232
Score = 139 bits (350), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 67/140 (48%), Positives = 89/140 (64%), Gaps = 5/140 (3%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
FDA+YRGESP PPWD P+ + G + G VLD GCG G++ ++LA
Sbjct 18 FDAVYRGESPFG-----KRPPWDIGEPQPAFVALEEAGLISGAVLDAGCGTGEDILHLAG 72
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY VTGLD+S A+ A+R+A + G+D FAV +A +L GY G FDTV+DCG+ H D
Sbjct 73 KGYAVTGLDLSSEAVAIARRKAEERGLDATFAVANALELAGYEGRFDTVVDCGLAHSFDA 132
Query 126 DGKRSYAASVHRATRPGATL 145
D R+YAA++HR RPGA +
Sbjct 133 DRLRTYAAALHRVCRPGALV 152
>gi|266631104|emb|CBH32104.1| putative dehydrogenase and domain with unknown function [Streptomyces
albaduncus]
Length=761
Score = 139 bits (349), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 82/189 (44%), Positives = 115/189 (61%), Gaps = 7/189 (3%)
Query 5 DFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLA 64
DF A+Y GE P+ PWD P+ ++ H G + GDVLD+GCGLGDNA +LA
Sbjct 533 DFRAIYAGEKDAS---PVQ--PWDIGRPQPALVAAHDAGEITGDVLDVGCGLGDNAAFLA 587
Query 65 RNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLD 124
G++VT +D++ A+ A+RRA D+GVDV+FAV DAT+LTGY G FDTV+D FH L
Sbjct 588 GRGHRVTAVDVAEAAVREARRRAEDSGVDVEFAVADATRLTGYDGRFDTVVDSACFHSLS 647
Query 125 DDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESL 184
+D + Y ++ ATRPG L + CF+ P + +LR+++GG W++ S+
Sbjct 648 EDERERYLRALRTATRPGGRLHMFCFAQEFEAPFPGPHRHTA-ASLREMVGGV-WNVLSV 705
Query 185 EPATVRREL 193
E AT L
Sbjct 706 EAATFASSL 714
>gi|254818552|ref|ZP_05223553.1| hypothetical protein MintA_01441 [Mycobacterium intracellulare
ATCC 13950]
Length=250
Score = 137 bits (346), Expect = 9e-31, Method: Compositional matrix adjust.
Identities = 82/197 (42%), Positives = 106/197 (54%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEQMYRDDRTSHGLP--TATPWDIGGPQPVVQQLVALGAIKGEVLDPGTGPGHHAIYYAS 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S A+ A+ A AGV V F V DATKL G+ G FDTV+DC +H
Sbjct 71 KGYSATGIDGSAGAIERARANAEKAGVSVNFEVADATKLDGFDGHFDTVVDCAFYHTFST 130
Query 126 DG--KRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +RSYA ++ RATRPGA L + F + RS +SE RDVL AGWDI
Sbjct 131 EPQLRRSYAEALRRATRPGARLYMFEFGEHNINGFKMLRS-LSESDFRDVLPDAGWDITY 189
Query 184 LEPATVRRELDGTEVEM 200
L T + + +E+
Sbjct 190 LGTTTYQVNISAESIEL 206
>gi|296171937|ref|ZP_06852982.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295893870|gb|EFG73642.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=249
Score = 136 bits (342), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 81/197 (42%), Positives = 106/197 (54%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR E GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 12 FEEMYRDERTSNGLP--TATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA 69
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCL-- 123
GY TG+D SP AL A+ A AGV V F + DAT+L G G FDTV+DC +H
Sbjct 70 KGYSATGIDGSPGALERARENARRAGVSVNFELADATRLEGLEGRFDTVVDCAFYHTFST 129
Query 124 DDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ + +RSY ++ RAT+PGA L + F + RS +SE RDVL GW+I
Sbjct 130 EPELQRSYVQALRRATKPGARLYMFEFGAHDVNGFKMMRS-LSENDFRDVLPLGGWEISY 188
Query 184 LEPATVRRELDGTEVEM 200
L P T + ++EM
Sbjct 189 LGPTTYLVNISVEQIEM 205
>gi|226362772|ref|YP_002780550.1| hypothetical protein ROP_33580 [Rhodococcus opacus B4]
gi|226241257|dbj|BAH51605.1| hypothetical protein [Rhodococcus opacus B4]
Length=219
Score = 136 bits (342), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 68/164 (42%), Positives = 98/164 (60%), Gaps = 2/164 (1%)
Query 26 PWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTAKR 85
PWD P+ ++ + G G VLD GCG GDNA+++A G +V G+D++ TA+ A+
Sbjct 39 PWDIGRPQPAIVHLASNGRFAGAVLDAGCGTGDNALHVASLGSRVLGVDVAETAVAIARE 98
Query 86 RASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPGATL 145
+A G+D +F VGDA +L +F+TV+DCG+FH + D + Y SV TRPGATL
Sbjct 99 KAGARGIDAEFVVGDAFELDRLGRSFETVLDCGLFHTFEGDERNDYVTSVASVTRPGATL 158
Query 146 LLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESLEPATV 189
+ CFS+A P D V E LR G GW +E++EP+ +
Sbjct 159 YVLCFSDAGPEDSG--PHPVGEDELRAAFGRGGWKVEAVEPSRI 200
>gi|41406223|ref|NP_959059.1| hypothetical protein MAP0125c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41394571|gb|AAS02442.1| hypothetical protein MAP_0125c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=231
Score = 130 bits (327), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 75/189 (40%), Positives = 103/189 (55%), Gaps = 11/189 (5%)
Query 6 FDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
F+A YRGESP GEG PPW P+ + G HGDVLD GCG ++YL
Sbjct 11 FEAAYRGESPEMGEG----ARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYL 66
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
A G+ GLD SPTA+ A+ +A+ G+ F V D + TGY G F T++D +FH
Sbjct 67 AERGFTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYDGRFGTIVDSTLFHS 126
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCF-SNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + + Y S+ RA PGA+ + F NAMP E P + V+E LR+V+G W I
Sbjct 127 MPVELREGYQRSIVRAAAPGASYFVLVFDRNAMPA--EGPVNAVTEDELREVVGKY-WVI 183
Query 182 ESLEPATVR 190
+ + PA +
Sbjct 184 DEIRPARIH 192
>gi|336458089|gb|EGO37075.1| Thiopurine S-methyltransferase (TPMT) [Mycobacterium avium subsp.
paratuberculosis S397]
Length=222
Score = 130 bits (326), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 75/188 (40%), Positives = 103/188 (55%), Gaps = 11/188 (5%)
Query 6 FDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
F+A YRGESP GEG PPW P+ + G HGDVLD GCG ++YL
Sbjct 2 FEAAYRGESPEMGEG----ARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYL 57
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
A G+ GLD SPTA+ A+ +A+ G+ F V D + TGY G F T++D +FH
Sbjct 58 AERGFTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYDGRFGTIVDSTLFHS 117
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCF-SNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + + Y S+ RA PGA+ + F NAMP E P + V+E LR+V+G W I
Sbjct 118 MPVELREGYQRSIVRAAAPGASYFVLVFDRNAMPA--EGPVNAVTEDELREVVGKY-WVI 174
Query 182 ESLEPATV 189
+ + PA +
Sbjct 175 DEIRPARI 182
>gi|312137777|ref|YP_004005113.1| SAM dependent methyltransferase [Rhodococcus equi 103S]
gi|311887116|emb|CBH46425.1| putative SAM dependent methyltransferase [Rhodococcus equi 103S]
Length=255
Score = 130 bits (326), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 80/194 (42%), Positives = 109/194 (57%), Gaps = 13/194 (6%)
Query 5 DFDALYRGE--------SPGEGLPPIT--TPPWDTKAPKDNVIGWHTGGWVHGDVLDIGC 54
DFDALYRG+ P E P T PWD + V + G +VLDIGC
Sbjct 16 DFDALYRGDFAAVNADAEPTETAPGFTFDRVPWDIGEAQPAVRALESSGQFAREVLDIGC 75
Query 55 GLGDNAIYLARNGYQVTGLDISPTALTTAKRRASDAGVD--VKFAVGDATKLTGYTGAFD 112
G G+NA++LA GY+V GLD +P A+ A+ RA G++ V+F V DAT L+ Y F
Sbjct 76 GPGENALFLASRGYRVWGLDAAPAAIDIARERARQRGMERGVEFEVADATDLSDYADRFA 135
Query 113 TVIDCGMFHCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRD 172
+VID ++HC +D + YAAS+ A RP A L + CFS+ +P P ++E LRD
Sbjct 136 SVIDSALYHCFPEDQRHRYAASLFGACRPQARLHVVCFSDRVPDGFPGP-YRITEDNLRD 194
Query 173 VLGGAGWDIESLEP 186
L AGW ++ +EP
Sbjct 195 TLTAAGWTVQRIEP 208
>gi|254773164|ref|ZP_05214680.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
avium subsp. avium ATCC 25291]
Length=222
Score = 129 bits (323), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 74/189 (40%), Positives = 103/189 (55%), Gaps = 11/189 (5%)
Query 6 FDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
F+A YRGESP GEG PPW P+ + G HGDVLD GCG ++YL
Sbjct 2 FEAAYRGESPEMGEG----ARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYL 57
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
A G+ GLD SPTA+ A+ +A+ G+ F V D + TGY G F T++D +FH
Sbjct 58 AERGFTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYDGRFGTIVDSTLFHS 117
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCF-SNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + + Y S+ +A PGA+ + F NAMP E P + V+E LR+V+G W I
Sbjct 118 MPVELREGYQRSIVQAAAPGASYFVLVFDRNAMPA--EGPVNAVTEDELREVVGKY-WVI 174
Query 182 ESLEPATVR 190
+ + PA +
Sbjct 175 DEIRPARIH 183
>gi|118465195|ref|YP_879415.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
avium 104]
gi|118166482|gb|ABK67379.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium
avium 104]
Length=231
Score = 129 bits (323), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 74/189 (40%), Positives = 103/189 (55%), Gaps = 11/189 (5%)
Query 6 FDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
F+A YRGESP GEG PPW P+ + G HGDVLD GCG ++YL
Sbjct 11 FEAAYRGESPEMGEG----ARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYL 66
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
A G+ GLD SPTA+ A+ +A+ G+ F V D + TGY G F T++D +FH
Sbjct 67 AERGFTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYDGRFGTIVDSTLFHS 126
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCF-SNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + + Y S+ +A PGA+ + F NAMP E P + V+E LR+V+G W I
Sbjct 127 MPVELREGYQRSIVQAAAPGASYFVLVFDRNAMPA--EGPVNAVTEDELREVVGKY-WVI 183
Query 182 ESLEPATVR 190
+ + PA +
Sbjct 184 DEIRPARIH 192
>gi|169629918|ref|YP_001703567.1| hypothetical protein MAB_2834c [Mycobacterium abscessus ATCC
19977]
gi|169241885|emb|CAM62913.1| Conserved hypothetical protein (methyltransferase?) [Mycobacterium
abscessus]
Length=227
Score = 128 bits (321), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 81/223 (37%), Positives = 115/223 (52%), Gaps = 24/223 (10%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F++ YRGE+P E L PPW P+ ++ G VHGDVLD GCG A+YLA
Sbjct 9 FESSYRGEAP-EQL--AARPPWSIGQPQPEILKLIEQGKVHGDVLDAGCGEAATALYLAE 65
Query 66 NGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHCLD 124
G+ GLD +PTA+ AK A++ G+ +V F V D + TGY G F T+ID +FH +
Sbjct 66 RGHTAVGLDAAPTAIQLAKGYAAERGLTNVTFDVADISNFTGYDGRFGTIIDSTLFHSMP 125
Query 125 DDGKRSYAASVHRATRPGATLLLSCFSN-AMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ + Y S+ RA PGA ++ F A PPD + P VSE LR+++ W ++
Sbjct 126 VELREGYQQSIVRAAAPGANYIVLVFDKAAFPPDIDGPHP-VSEPELREIVSKY-WTVDD 183
Query 184 LEPATVRRELDGTE-----------------VEMAFWNVRAQR 209
+ PA + DG + V MA W ++A R
Sbjct 184 ISPARLYANGDGFQDGGAQRFAEFREESNGWVSMAGWLLQAHR 226
>gi|325675063|ref|ZP_08154749.1| thiopurine S-methyltransferase family protein [Rhodococcus equi
ATCC 33707]
gi|325554024|gb|EGD23700.1| thiopurine S-methyltransferase family protein [Rhodococcus equi
ATCC 33707]
Length=253
Score = 127 bits (320), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 79/197 (41%), Positives = 110/197 (56%), Gaps = 17/197 (8%)
Query 5 DFDALYRGE-----------SPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIG 53
DFDALYRG+ +PG + PWD + V + G +VLDIG
Sbjct 16 DFDALYRGDFAAVNADAEPTAPGFTFDRV---PWDIGEAQPAVRALESSGQFAREVLDIG 72
Query 54 CGLGDNAIYLARNGYQVTGLDISPTALTTAKRRASDAGVD--VKFAVGDATKLTGYTGAF 111
CG G+NA++LA GY+V GLD +P A+ A+ RA G++ V+F V DAT L+ Y F
Sbjct 73 CGPGENALFLASRGYRVWGLDAAPAAIDIARERARQRGMERGVEFEVADATDLSDYADRF 132
Query 112 DTVIDCGMFHCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLR 171
+VID ++HC +D + YAAS+ A RP A L + CFS+ +P P ++E LR
Sbjct 133 VSVIDSALYHCFPEDQRHRYAASLFGACRPQARLHVVCFSDRVPDGFPGP-YRITEDNLR 191
Query 172 DVLGGAGWDIESLEPAT 188
D L AGW ++ +EP T
Sbjct 192 DTLTAAGWTVQRIEPTT 208
>gi|118468119|ref|YP_886428.1| methyltransferase type 12 [Mycobacterium smegmatis str. MC2 155]
gi|118169406|gb|ABK70302.1| methyltransferase type 12 [Mycobacterium smegmatis str. MC2 155]
Length=211
Score = 127 bits (319), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 76/201 (38%), Positives = 106/201 (53%), Gaps = 23/201 (11%)
Query 24 TPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTA 83
T PW P+ V+ G + VLD+GCG G++ I L R GY V G+D SP A+ A
Sbjct 18 TAPWVIGEPQPAVVELERAGLIRSRVLDVGCGAGEHTILLTRLGYDVLGIDFSPQAIEMA 77
Query 84 KRRASDAGVDVKFAVGDATKLTGY-TGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPG 142
+ A GVD +FAVGDA L GA+DT++D +FH DD +++Y AS+H RPG
Sbjct 78 RENARGRGVDARFAVGDAMALGDLGDGAYDTILDSALFHIFDDADRQTYVASLHAGCRPG 137
Query 143 ATLLLSCFSNA---MPPDEEWPRSTVSEQTLRDVLGGAGWDIESLEPATVRRELD----- 194
T+ + S+A P+ VSE+ +R G GWD+E+LE T R +
Sbjct 138 GTVHILALSDAGRGFGPE-------VSEEQIRKAFGD-GWDLEALETTTYRGVVGPVHAE 189
Query 195 ------GTEVEMAFWNVRAQR 209
GT+V+ W RA+R
Sbjct 190 AIGLPVGTQVDEPAWLARARR 210
>gi|120402886|ref|YP_952715.1| type 11 methyltransferase [Mycobacterium vanbaalenii PYR-1]
gi|119955704|gb|ABM12709.1| Methyltransferase type 11 [Mycobacterium vanbaalenii PYR-1]
Length=209
Score = 127 bits (318), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 77/218 (36%), Positives = 112/218 (52%), Gaps = 33/218 (15%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
FD Y+ + TPPW P+ ++ G + G VLD+GCG G++ I LAR
Sbjct 10 FDEFYKNQ----------TPPWVIGEPQQAIVELEQAGLIGGRVLDVGCGTGEHTILLAR 59
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY V G+D +PTA+ A+R A GVD +F + DA L G +DT++D +FH DD
Sbjct 60 AGYDVLGIDGAPTAVEQARRNAEAQGVDARFELADALHL-GPDPTYDTIVDSALFHIFDD 118
Query 126 DGKRSYAASVHRATRPGATLLLSCFSNA---MPPDEEWPRSTVSEQTLRDVLGGAGWDIE 182
+ +Y S+H ATRPG+ + L S++ P+ VSE T+R GAGW++E
Sbjct 119 ADRATYVRSLHAATRPGSVVHLLALSDSGRGFGPE-------VSEHTIRAAF-GAGWEVE 170
Query 183 SLEPATVRREL-----------DGTEVEMAFWNVRAQR 209
+L T R + GT V+ W+ R +R
Sbjct 171 ALTETTYRGVVIDAHTEALNLPAGTVVDEPAWSARIRR 208
>gi|220915318|ref|YP_002490622.1| type 11 methyltransferase [Anaeromyxobacter dehalogenans 2CP-1]
gi|219953172|gb|ACL63556.1| Methyltransferase type 11 [Anaeromyxobacter dehalogenans 2CP-1]
Length=197
Score = 126 bits (317), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 65/151 (44%), Positives = 89/151 (59%), Gaps = 2/151 (1%)
Query 24 TPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTA 83
TPPWD P+ ++ G + GDVLD+GCG G+NA++LA G +V G+D SPTA+ A
Sbjct 17 TPPWDIGRPQAELVALAEAGEIVGDVLDVGCGTGENALHLAALGKRVLGVDGSPTAIARA 76
Query 84 KRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPGA 143
+A+ G+ V F V DA L F+T +DCG+FH D +R+YA S+ PG+
Sbjct 77 LEKAAARGLQVPFLVADALDLKALHRRFETAVDCGLFHVFDRADRRTYAQSLTEVLSPGS 136
Query 144 TLLLSCFSNAMPPDEEWPRSTVSEQTLRDVL 174
TL L CFS+ PP PR +SE +RD
Sbjct 137 TLHLLCFSDEEPPG-PGPRR-ISESDVRDAF 165
>gi|197120607|ref|YP_002132558.1| type 11 methyltransferase [Anaeromyxobacter sp. K]
gi|196170456|gb|ACG71429.1| Methyltransferase type 11 [Anaeromyxobacter sp. K]
Length=197
Score = 126 bits (316), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 64/151 (43%), Positives = 88/151 (59%), Gaps = 2/151 (1%)
Query 24 TPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTA 83
TPPWD P+ ++ G + GDVLD+GCG G+NA++LA G +V G+D SPTA+ A
Sbjct 17 TPPWDIGRPQAELVALAEAGEIVGDVLDVGCGTGENALHLAALGKRVMGVDGSPTAIARA 76
Query 84 KRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPGA 143
+A+ G+ V F V DA L F+T +DCG+FH D +R+YA S+ PG+
Sbjct 77 LEKAAARGLQVPFLVADALDLKALHRRFETAVDCGLFHVFDRADRRTYAQSLTEVLSPGS 136
Query 144 TLLLSCFSNAMPPDEEWPRSTVSEQTLRDVL 174
TL L CFS+ PP R +SE +RD
Sbjct 137 TLHLLCFSDEEPPGPGPHR--ISESDVRDAF 165
>gi|289570849|ref|ZP_06451076.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
gi|289544603|gb|EFD48251.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
Length=250
Score = 125 bits (315), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 78/197 (40%), Positives = 102/197 (52%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S A+ A+ A AGV V F VGDAT L G G FDTV+DC +H
Sbjct 71 KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST 130
Query 126 --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +R Y ++ RA++PGA L + FS PRS +SE R VL GW+I
Sbjct 131 APELQRCYVRALRRASKPGARLYMFEFSEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY 189
Query 184 LEPATVRRELDGTEVEM 200
L T + L +E+
Sbjct 190 LGTTTYQVNLSVEALEL 206
>gi|118618639|ref|YP_906971.1| methyltransferase [Mycobacterium ulcerans Agy99]
gi|118570749|gb|ABL05500.1| methyltransferase [Mycobacterium ulcerans Agy99]
Length=249
Score = 124 bits (312), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 77/196 (40%), Positives = 103/196 (53%), Gaps = 5/196 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G V G+VLD G G G +AIY A
Sbjct 12 FEEMYRDQRVAHGLPAAT--PWDIGGPQPVVEQLVALGAVKGEVLDPGTGPGHHAIYYAS 69
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S TA+ A+ A+ AGV V F V DAT+L G FDTV+DC +H
Sbjct 70 KGYSATGIDGSATAIERARDNAAKAGVSVNFQVADATRLEGLDNRFDTVVDCAFYHTFGT 129
Query 126 --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +RSY ++ RAT+PGA L + F RS + E+ R++L GW+I
Sbjct 130 APELQRSYVQALWRATKPGARLYMYEFGAHQVNGLTAIRS-LPEENFREMLPLGGWEITY 188
Query 184 LEPATVRRELDGTEVE 199
L P T R + +E
Sbjct 189 LGPTTYRTTVSMETLE 204
>gi|183982054|ref|YP_001850345.1| methyltransferase [Mycobacterium marinum M]
gi|183175380|gb|ACC40490.1| methyltransferase [Mycobacterium marinum M]
Length=249
Score = 124 bits (312), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 77/196 (40%), Positives = 103/196 (53%), Gaps = 5/196 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G V G+VLD G G G +AIY A
Sbjct 12 FEEMYRDQRVAHGLPAAT--PWDIGGPQPVVEQLVALGAVKGEVLDPGTGPGHHAIYYAS 69
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S TA+ A+ A+ AGV V F V DAT+L G FDTV+DC +H
Sbjct 70 KGYSATGIDGSATAIERARDNAAKAGVSVNFQVADATRLEGLDNRFDTVVDCAFYHTFGT 129
Query 126 --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +RSY ++ RAT+PGA L + F RS + E+ R++L GW+I
Sbjct 130 APELQRSYVRALWRATKPGARLYMYEFGAHQVNGLTAIRS-LPEENFREMLPLGGWEITY 188
Query 184 LEPATVRRELDGTEVE 199
L P T R + +E
Sbjct 189 LGPTTYRTTVSMETLE 204
>gi|15609812|ref|NP_217191.1| hypothetical protein Rv2675c [Mycobacterium tuberculosis H37Rv]
gi|15842213|ref|NP_337250.1| hypothetical protein MT2749 [Mycobacterium tuberculosis CDC1551]
gi|31793847|ref|NP_856340.1| hypothetical protein Mb2694c [Mycobacterium bovis AF2122/97]
72 more sequence titles
Length=250
Score = 124 bits (311), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 77/197 (40%), Positives = 101/197 (52%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S A+ A+ A AGV V F VGDAT L G G FDTV+DC +H
Sbjct 71 KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST 130
Query 126 --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +R Y ++ RA++PGA L + F PRS +SE R VL GW+I
Sbjct 131 APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY 189
Query 184 LEPATVRRELDGTEVEM 200
L T + L +E+
Sbjct 190 LGTTTYQVNLSVEALEL 206
>gi|169627497|ref|YP_001701146.1| methyltransferase [Mycobacterium abscessus ATCC 19977]
gi|169239464|emb|CAM60492.1| Possible methyltransferase [Mycobacterium abscessus]
Length=232
Score = 124 bits (310), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 74/196 (38%), Positives = 102/196 (53%), Gaps = 8/196 (4%)
Query 4 IDFDALYRGESP-GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIY 62
+ FDA YRGE+P G G PPW P+ + G V G+VLD GCG ++Y
Sbjct 12 LAFDAAYRGEAPDGRG----ARPPWSIGEPQPEIAMLIAEGKVRGEVLDAGCGEAATSLY 67
Query 63 LARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFH 121
LA G+ GLD +P A+ AK A++ G+ + FAV D + TGY G FDT+ID +FH
Sbjct 68 LAEVGHTTVGLDSAPKAIELAKGYAAERGLTNASFAVADISSFTGYDGRFDTIIDSTLFH 127
Query 122 CLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + Y S+ RA PGA + F A P E P + V+E LRD + W I
Sbjct 128 SMPVGLRAGYQRSIVRAAAPGARYYVLVFDRAAFPAES-PVNAVTENELRDAVSKY-WAI 185
Query 182 ESLEPATVRRELDGTE 197
+ + PA + +G E
Sbjct 186 DEIRPAKIYANFNGFE 201
>gi|254365337|ref|ZP_04981382.1| conserved hypothetical protein [Mycobacterium tuberculosis str.
Haarlem]
gi|134150850|gb|EBA42895.1| conserved hypothetical protein [Mycobacterium tuberculosis str.
Haarlem]
Length=250
Score = 124 bits (310), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 77/197 (40%), Positives = 101/197 (52%), Gaps = 5/197 (2%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F+ +YR + GLP T PWD P+ V G + G+VLD G G G +AIY A
Sbjct 13 FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA 70
Query 66 NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD 125
GY TG+D S A+ A+ A AGV V F VGDAT L G G FDTV+DC +H
Sbjct 71 KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST 130
Query 126 --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES 183
+ +R Y ++ RA++PGA L + F PRS +SE R VL GW+I
Sbjct 131 APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY 189
Query 184 LEPATVRRELDGTEVEM 200
L T + L +E+
Sbjct 190 LGTTTYQVNLSVEALEL 206
>gi|288916265|ref|ZP_06410644.1| Methyltransferase type 11 [Frankia sp. EUN1f]
gi|288352244|gb|EFC86442.1| Methyltransferase type 11 [Frankia sp. EUN1f]
Length=225
Score = 124 bits (310), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 67/190 (36%), Positives = 101/190 (54%), Gaps = 14/190 (7%)
Query 5 DFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLA 64
DFD Y+G TPPWD P+ G + G VLD+GCG G++A+ A
Sbjct 21 DFDIFYQG-----------TPPWDIGRPQAAFQALANAGRLRGRVLDVGCGTGEHALLAA 69
Query 65 RNGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLD 124
G V G+D S A+ AK +A++ G+ +F V +A +L FDTV+DCG+FH L
Sbjct 70 SLGLDVVGVDTSALAIERAKAKAAERGLRARFRVENALRLADLPERFDTVLDCGLFHVLT 129
Query 125 DDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESL 184
D+ + +Y ++H PG + CFS+ +P D PR +S+ +R GW ++++
Sbjct 130 DEDREAYVRALHSVLHPGGHYYMLCFSDQVPGD-IGPRR-ISQDEIRSSFAD-GWQVDAV 186
Query 185 EPATVRRELD 194
EPAT+ D
Sbjct 187 EPATLEITFD 196
>gi|296168231|ref|ZP_06850204.1| thiopurine S-methyltransferase family protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295896803|gb|EFG76434.1| thiopurine S-methyltransferase family protein [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=246
Score = 123 bits (309), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 68/161 (43%), Positives = 90/161 (56%), Gaps = 4/161 (2%)
Query 26 PWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTAKR 85
PWD P+ V G + G+VLD G G G +AI+ A GY TG+D SP+A+ AKR
Sbjct 24 PWDIGGPQPAVQQLVAYGGIRGEVLDPGTGPGYHAIHFAAQGYSATGIDDSPSAIERAKR 83
Query 86 RASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDG--KRSYAASVHRATRPGA 143
A AGV+V F V DAT+L G+ G FDTV+D +H +DG + YA ++HRATRPGA
Sbjct 84 NAERAGVEVDFQVADATRLEGFDGRFDTVVDSAFYHVFLNDGVVQTRYAQALHRATRPGA 143
Query 144 TLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESL 184
L + FS +W + + V G GW I+ L
Sbjct 144 RLYMFEFSPHNVNGLQW--TAIPADNFERVFGANGWRIDYL 182
>gi|254822596|ref|ZP_05227597.1| hypothetical protein MintA_21884 [Mycobacterium intracellulare
ATCC 13950]
Length=222
Score = 123 bits (308), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 72/189 (39%), Positives = 100/189 (53%), Gaps = 11/189 (5%)
Query 6 FDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYL 63
F+A YRGE+P GEG PPW P+ + G HGDVLD GCG ++YL
Sbjct 2 FEAAYRGEAPEMGEG----NRPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYL 57
Query 64 ARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMFHC 122
A G+ GLD SPTA+ A+ +A+ G+ F V D + TGY G F T++D +FH
Sbjct 58 AERGFTTVGLDQSPTAIELAREKAARRGLTSASFDVADISAFTGYDGRFGTIVDSTLFHS 117
Query 123 LDDDGKRSYAASVHRATRPGATLLLSCFSN-AMPPDEEWPRSTVSEQTLRDVLGGAGWDI 181
+ + + Y S+ RA PGA+ + F AMP D P + V+E LRD + W I
Sbjct 118 MPVELRDGYQQSIVRAAAPGASYFVLVFDRAAMPAD--GPVNAVTEDELRDAVSKY-WVI 174
Query 182 ESLEPATVR 190
+ + PA +
Sbjct 175 DEIRPARIH 183
>gi|240172077|ref|ZP_04750736.1| hypothetical protein MkanA1_22365 [Mycobacterium kansasii ATCC
12478]
Length=228
Score = 122 bits (306), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 75/211 (36%), Positives = 109/211 (52%), Gaps = 10/211 (4%)
Query 6 FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR 65
F++ YRGE P G P PPW P+ + G HGDVLD GCG ++ LA
Sbjct 9 FESAYRGEVPSLGSGP--KPPWSIGEPQPELAALIEQGKFHGDVLDAGCGEAAISLQLAE 66
Query 66 NGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGY----TGAFDTVIDCGMF 120
GY GLD+SPTA+ A+ A+ G+ + FAV D + TGY G F T++D +F
Sbjct 67 LGYTTVGLDLSPTAIELARAEAAKRGLSNATFAVADISDFTGYPPGSEGRFGTIVDSTLF 126
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
H L + + Y SV RA PGA+ + F A P E P + V+E LR+++G W
Sbjct 127 HSLPVEAREGYLQSVVRAAAPGASYFVLVFDRASMP--EGPANAVTEDELRELVGRY-WA 183
Query 181 IESLEPATVRRELDGTEVEMAFWNVRAQRRG 211
I+ ++PA + L + + ++R + G
Sbjct 184 IDEIKPARLHGNLPESFSALPLGDLRDEPNG 214
>gi|340625587|ref|YP_004744039.1| putative benzoquinone methyltransferase [Mycobacterium canettii
CIPT 140010059]
gi|340003777|emb|CCC42903.1| putative benzoquinone methyltransferase (methylase) [Mycobacterium
canettii CIPT 140010059]
Length=241
Score = 122 bits (305), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 69/189 (37%), Positives = 103/189 (55%), Gaps = 10/189 (5%)
Query 4 IDFDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAI 61
++F++ YRGES GEG+ PPW P+ + G GDVLD+GCG ++
Sbjct 23 LEFESAYRGESVAFGEGV----RPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAISL 78
Query 62 YLARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMF 120
LA G+ GLD+SPTA+ A+ A+ G+ + F V DA+ TGY G FDT++D +F
Sbjct 79 ALAERGHTTVGLDLSPTAVELARHEAAKRGLANASFEVADASSFTGYDGRFDTIVDSTLF 138
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
H + + + Y S+ RA PGA+ + F A P E P + V+E LR + W
Sbjct 139 HSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP--EGPINAVTEDELRAAVSKY-WI 195
Query 181 IESLEPATV 189
I+ ++PA +
Sbjct 196 IDEIKPARL 204
>gi|111017239|ref|YP_700211.1| hypothetical protein RHA1_ro00217 [Rhodococcus jostii RHA1]
gi|110816769|gb|ABG92053.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=226
Score = 121 bits (304), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 67/162 (42%), Positives = 94/162 (59%), Gaps = 4/162 (2%)
Query 26 PWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTAKR 85
PWD P+ V+ + G G VLD GCG G+NA+++A G QV G+D++ TAL A+
Sbjct 38 PWDVGRPQPAVVRVASEGGFAGAVLDAGCGTGENALHVASLGLQVLGVDVAETALAIARD 97
Query 86 RASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPGATL 145
+A D ++V+FA+ DA +L G FDTV+DCG+FH D + Y ASV T G T+
Sbjct 98 KADDRRIEVEFALADAFQLDGMGRRFDTVLDCGLFHTFDAAERPRYVASVASVTEHGGTV 157
Query 146 LLSCFSNAMPPDEEWPRSTVSEQTLRDVLG-GAGWDIESLEP 186
+ CFS+A P P VS + LR G GW + ++EP
Sbjct 158 YVLCFSDAGPDTGPHP---VSREELRAAFDPGDGWKVAAIEP 196
>gi|298524048|ref|ZP_07011457.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
gi|298493842|gb|EFI29136.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
gi|339293605|gb|AEJ45716.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CCDC5079]
gi|339297245|gb|AEJ49355.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CCDC5180]
Length=238
Score = 120 bits (301), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 68/189 (36%), Positives = 102/189 (54%), Gaps = 10/189 (5%)
Query 4 IDFDALYRGESP--GEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAI 61
++F++ YRGES GEG+ PPW P+ + G GDVLD+GCG ++
Sbjct 20 LEFESAYRGESVAFGEGV----RPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAISL 75
Query 62 YLARNGYQVTGLDISPTALTTAKRRASDAGV-DVKFAVGDATKLTGYTGAFDTVIDCGMF 120
LA G+ GLD+SP A+ A+ A+ G+ + F V DA+ TGY G FDT++D +F
Sbjct 76 ALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYDGRFDTIVDSTLF 135
Query 121 HCLDDDGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWD 180
H + + + Y S+ RA PGA+ + F A P E P + V+E LR + W
Sbjct 136 HSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP--EGPINAVTEDELRAAVSKY-WI 192
Query 181 IESLEPATV 189
I+ ++PA +
Sbjct 193 IDEIKPARL 201
>gi|84617327|emb|CAI94687.1| hypothetical protein [Streptomyces achromogenes subsp. rubradiris]
Length=331
Score = 120 bits (301), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 66/166 (40%), Positives = 92/166 (56%), Gaps = 3/166 (1%)
Query 24 TPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTA 83
TPPW+T P+ + G G VLD+GCG G+ A+ A G G+D + TA+ A
Sbjct 150 TPPWETGRPQPALRDLAEAGAFRGRVLDVGCGTGEVALMAAALGLPTVGIDPASTAIEIA 209
Query 84 KRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDDDGKRSYAASVHRATRPGA 143
+R+A + G+ +F VGDA +L FDTV+DCG+FH D + YA S+ P A
Sbjct 210 RRKAEERGLQARFLVGDALELGAMGEQFDTVLDCGLFHVFSDAERVRYADSLATVMPPDA 269
Query 144 TLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIESLEPATV 189
L L CFS+ PPD PR VS+ +R GW ++S+EPA +
Sbjct 270 RLFLLCFSDRHPPD-IGPRR-VSQDEIRATFAD-GWRVDSIEPAML 312
Lambda K H
0.317 0.137 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 252352077426
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40