BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1392 Length=403 Score E Sequences producing significant alignments: (Bits) Value gi|15840851|ref|NP_335888.1| S-adenosylmethionine synthetase [My... 812 0.0 gi|254231639|ref|ZP_04924966.1| S-adenosylmethionine synthetase ... 810 0.0 gi|15608531|ref|NP_215908.1| S-adenosylmethionine synthetase [My... 810 0.0 gi|343781313|pdb|3TDE|A Chain A, Crystal Structure Of S-Adenosyl... 810 0.0 gi|121637322|ref|YP_977545.1| S-adenosylmethionine synthetase [M... 809 0.0 gi|31792586|ref|NP_855079.1| S-adenosylmethionine synthetase [My... 808 0.0 gi|340626406|ref|YP_004744858.1| putative S-adenosylmethionine s... 808 0.0 gi|294994953|ref|ZP_06800644.1| S-adenosylmethionine synthetase ... 807 0.0 gi|240172963|ref|ZP_04751621.1| S-adenosylmethionine synthetase ... 781 0.0 gi|183982218|ref|YP_001850509.1| s-adenosylmethionine synthetase... 771 0.0 gi|333361539|pdb|3RV2|A Chain A, Crystal Structure Of S-Adenosyl... 771 0.0 gi|118617406|ref|YP_905738.1| S-adenosylmethionine synthetase [M... 769 0.0 gi|296170742|ref|ZP_06852314.1| methionine adenosyltransferase [... 759 0.0 gi|118465537|ref|YP_882564.1| S-adenosylmethionine synthetase [M... 755 0.0 gi|335892564|pdb|3S82|A Chain A, Structure Of A S-Adenosylmethio... 754 0.0 gi|41407224|ref|NP_960060.1| S-adenosylmethionine synthetase [My... 754 0.0 gi|254821097|ref|ZP_05226098.1| S-adenosylmethionine synthetase ... 753 0.0 gi|15827200|ref|NP_301463.1| S-adenosylmethionine synthetase [My... 749 0.0 gi|342858674|ref|ZP_08715329.1| S-adenosylmethionine synthetase ... 744 0.0 gi|333990942|ref|YP_004523556.1| s-adenosylmethionine synthetase... 739 0.0 gi|108799340|ref|YP_639537.1| S-adenosylmethionine synthetase [M... 718 0.0 gi|120403654|ref|YP_953483.1| S-adenosylmethionine synthetase [M... 711 0.0 gi|145224319|ref|YP_001134997.1| S-adenosylmethionine synthetase... 711 0.0 gi|118468007|ref|YP_887371.1| S-adenosylmethionine synthetase [M... 700 0.0 gi|169629904|ref|YP_001703553.1| S-adenosylmethionine synthetase... 668 0.0 gi|54025583|ref|YP_119825.1| S-adenosylmethionine synthetase [No... 650 0.0 gi|226306498|ref|YP_002766458.1| S-adenosylmethionine synthetase... 644 0.0 gi|317505994|ref|ZP_07963826.1| methionine adenosyltransferase [... 641 0.0 gi|296394690|ref|YP_003659574.1| S-adenosylmethionine synthetase... 639 0.0 gi|296140274|ref|YP_003647517.1| S-adenosylmethionine synthetase... 637 1e-180 gi|256377203|ref|YP_003100863.1| S-adenosylmethionine synthetase... 632 3e-179 gi|262202275|ref|YP_003273483.1| S-adenosylmethionine synthetase... 632 4e-179 gi|111024108|ref|YP_707080.1| S-adenosylmethionine synthetase [R... 630 1e-178 gi|312139575|ref|YP_004006911.1| s-adenosylmethionine synthetase... 630 1e-178 gi|226366348|ref|YP_002784131.1| S-adenosylmethionine synthetase... 629 3e-178 gi|325672541|ref|ZP_08152237.1| methionine adenosyltransferase [... 627 1e-177 gi|257055595|ref|YP_003133427.1| methionine adenosyltransferase ... 625 3e-177 gi|325001020|ref|ZP_08122132.1| S-adenosylmethionine synthetase ... 624 7e-177 gi|333919532|ref|YP_004493113.1| S-adenosylmethionine synthase [... 624 1e-176 gi|326382167|ref|ZP_08203859.1| S-adenosylmethionine synthetase ... 623 2e-176 gi|327309918|ref|YP_004336816.1| S-adenosylmethionine synthase [... 622 3e-176 gi|343924558|ref|ZP_08764106.1| S-adenosylmethionine synthase [G... 622 3e-176 gi|256379242|ref|YP_003102902.1| S-adenosylmethionine synthetase... 621 6e-176 gi|331697242|ref|YP_004333481.1| S-adenosylmethionine synthase [... 620 9e-176 gi|134098673|ref|YP_001104334.1| methionine adenosyltransferase ... 618 6e-175 gi|302525875|ref|ZP_07278217.1| methionine adenosyltransferase [... 616 2e-174 gi|257056683|ref|YP_003134515.1| methionine adenosyltransferase ... 615 4e-174 gi|298256329|gb|ADI71438.1| putative methionine adenosyltransfer... 608 6e-172 gi|254383678|ref|ZP_04999027.1| SAM synthetase [Streptomyces sp.... 606 2e-171 gi|258654281|ref|YP_003203437.1| S-adenosylmethionine synthetase... 605 3e-171 >gi|15840851|ref|NP_335888.1| S-adenosylmethionine synthetase [Mycobacterium tuberculosis CDC1551] gi|253799559|ref|YP_003032560.1| S-adenosylmethionine synthetase metK [Mycobacterium tuberculosis KZN 1435] gi|306780723|ref|ZP_07419060.1| S-adenosylmethionine synthetase metK [Mycobacterium tuberculosis SUMu002] 13 more sequence titles Length=406 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/403 (100%), Positives = 403/403 (100%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 4 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 63 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 64 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 123 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 124 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 183 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 184 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 243 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 244 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 303 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 304 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 363 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 364 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 406 >gi|254231639|ref|ZP_04924966.1| S-adenosylmethionine synthetase metK [Mycobacterium tuberculosis C] gi|124600698|gb|EAY59708.1| S-adenosylmethionine synthetase metK [Mycobacterium tuberculosis C] Length=406 Score = 810 bits (2093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/403 (99%), Positives = 403/403 (100%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 4 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 63 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 64 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 123 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 124 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 183 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNT+LDDLAHETLDAST Sbjct 184 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTMLDDLAHETLDAST 243 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 244 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 303 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 304 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 363 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 364 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 406 >gi|15608531|ref|NP_215908.1| S-adenosylmethionine synthetase [Mycobacterium tuberculosis H37Rv] gi|148661183|ref|YP_001282706.1| S-adenosylmethionine synthetase [Mycobacterium tuberculosis H37Ra] gi|148822612|ref|YP_001287366.1| S-adenosylmethionine synthetase [Mycobacterium tuberculosis F11] 52 more sequence titles Length=403 Score = 810 bits (2093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/403 (99%), Positives = 403/403 (100%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 >gi|343781313|pdb|3TDE|A Chain A, Crystal Structure Of S-Adenosylmethionine Synthetase Rv1392 From Mycobacterium Tuberculosis gi|343781314|pdb|3TDE|B Chain B, Crystal Structure Of S-Adenosylmethionine Synthetase Rv1392 From Mycobacterium Tuberculosis gi|343781315|pdb|3TDE|C Chain C, Crystal Structure Of S-Adenosylmethionine Synthetase Rv1392 From Mycobacterium Tuberculosis gi|343781316|pdb|3TDE|D Chain D, Crystal Structure Of S-Adenosylmethionine Synthetase Rv1392 From Mycobacterium Tuberculosis Length=408 Score = 810 bits (2093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/403 (100%), Positives = 403/403 (100%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 6 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 65 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 66 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 125 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 126 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 185 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 186 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 245 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 246 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 305 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 306 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 365 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 366 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 408 >gi|121637322|ref|YP_977545.1| S-adenosylmethionine synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989797|ref|YP_002644484.1| S-adenosylmethionine synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|158512949|sp|A1KII1.1|METK_MYCBP RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|254810921|sp|C1AN37.1|METK_MYCBT RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|121492969|emb|CAL71440.1| Probable S-adenosylmethionine synthetase metK [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772910|dbj|BAH25716.1| S-adenosylmethionine synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|341601341|emb|CCC64014.1| probable S-adenosylmethionine synthetase metK [Mycobacterium bovis BCG str. Moreau RDJ] Length=403 Score = 809 bits (2089), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/403 (99%), Positives = 403/403 (100%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPV+LDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 181 KTQVTIAYEDNVPVQLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 >gi|31792586|ref|NP_855079.1| S-adenosylmethionine synthetase [Mycobacterium bovis AF2122/97] gi|44888140|sp|Q7U051.1|METK_MYCBO RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|31618175|emb|CAD94288.1| PROBABLE S-ADENOSYLMETHIONINE SYNTHETASE METK (MAT) (AdoMet synthetase) (Methionine adenosyltransferase) [Mycobacterium bovis AF2122/97] Length=403 Score = 808 bits (2088), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/403 (99%), Positives = 402/403 (99%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEV Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVA 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 >gi|340626406|ref|YP_004744858.1| putative S-adenosylmethionine synthetase [Mycobacterium canettii CIPT 140010059] gi|340004596|emb|CCC43740.1| putative S-adenosylmethionine synthetase METK (MAT) (AdoMet synthetase) (methionine adenosyltransferase) [Mycobacterium canettii CIPT 140010059] Length=403 Score = 808 bits (2086), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/403 (99%), Positives = 402/403 (99%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 >gi|294994953|ref|ZP_06800644.1| S-adenosylmethionine synthetase [Mycobacterium tuberculosis 210] Length=403 Score = 807 bits (2085), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/403 (99%), Positives = 402/403 (99%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPL+SQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLESQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHA DIDLEKTLDPDIREKVLNTVLDDLAHETLDAST Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAGDIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 >gi|240172963|ref|ZP_04751621.1| S-adenosylmethionine synthetase [Mycobacterium kansasii ATCC 12478] Length=403 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/403 (96%), Positives = 396/403 (99%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAEDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AK AFADITNTVRARIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TTAKAAFADITNTVRARILQIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIRE VL +VLD+LAH+TLDAS Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREHVLKSVLDELAHQTLDASQ 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTET DPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETVDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYAPTAAYGHFGRTD+ELPWEQL+KVDDLKRAI Sbjct 361 IIRDLDLLRPIYAPTAAYGHFGRTDIELPWEQLNKVDDLKRAI 403 >gi|183982218|ref|YP_001850509.1| s-adenosylmethionine synthetase MetK [Mycobacterium marinum M] gi|238690946|sp|B2HP50.1|METK_MYCMM RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|183175544|gb|ACC40654.1| s-adenosylmethionine synthetase MetK [Mycobacterium marinum M] Length=403 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/403 (95%), Positives = 393/403 (98%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDA+SDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAVSDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITN VR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TTAKEAFADITNIVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYED VPVRLDTVVISTQHA DIDL KTLDPDIRE+VL TVLDDLAH+TLDAS Sbjct 181 KTQVTIAYEDRVPVRLDTVVISTQHADDIDLVKTLDPDIREQVLKTVLDDLAHDTLDASA 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFG+E DPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSEAVDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDV+LPWE+LDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVDLPWERLDKVDDLKRAI 403 >gi|333361539|pdb|3RV2|A Chain A, Crystal Structure Of S-Adenosylmethionine Synthetase From Mycobacterium Marinum gi|333361540|pdb|3RV2|B Chain B, Crystal Structure Of S-Adenosylmethionine Synthetase From Mycobacterium Marinum Length=407 Score = 771 bits (1990), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/403 (95%), Positives = 393/403 (98%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDA+SDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 5 MSEKGRLFTSESVTEGHPDKICDAVSDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 64 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITN VR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 65 TTAKEAFADITNIVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHEARV 124 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 125 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 184 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYED VPVRLDTVVISTQHA DIDL KTLDPDIRE+VL TVLDDLAH+TLDAS Sbjct 185 KTQVTIAYEDRVPVRLDTVVISTQHADDIDLVKTLDPDIREQVLKTVLDDLAHDTLDASA 244 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 245 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 304 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFG+E DPVKIEKAIGEVFDLRPGA Sbjct 305 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSEAVDPVKIEKAIGEVFDLRPGA 364 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDV+LPWE+LDKVDDLKRAI Sbjct 365 IIRDLNLLRPIYAPTAAYGHFGRTDVDLPWERLDKVDDLKRAI 407 >gi|118617406|ref|YP_905738.1| S-adenosylmethionine synthetase [Mycobacterium ulcerans Agy99] gi|158512386|sp|A0PPJ8.1|METK_MYCUA RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|118569516|gb|ABL04267.1| s-adenosylmethionine synthetase MetK [Mycobacterium ulcerans Agy99] Length=403 Score = 769 bits (1985), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/403 (95%), Positives = 392/403 (98%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDA+SDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAVSDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITN VR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TTAKEAFADITNIVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYED VPVRLDTVVISTQHA DIDL KTLDPDIRE+VL TVLDDLAH+TLDAS Sbjct 181 KTQVTIAYEDRVPVRLDTVVISTQHADDIDLVKTLDPDIREQVLKTVLDDLAHDTLDASA 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKNVVAAGLAE VEVQVAYAIGKAAPVGLFVETFG+E DPVKIEKAIGEVFDLRPGA Sbjct 301 WVAKNVVAAGLAEGVEVQVAYAIGKAAPVGLFVETFGSEAVDPVKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDLNLLRPIYAPTAAYGHFGRTDV+LPWE+LDKVDDLKRAI Sbjct 361 IIRDLNLLRPIYAPTAAYGHFGRTDVDLPWERLDKVDDLKRAI 403 >gi|296170742|ref|ZP_06852314.1| methionine adenosyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894557|gb|EFG74294.1| methionine adenosyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=403 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/403 (93%), Positives = 389/403 (97%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVRARILEIGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHE RV Sbjct 61 TTAKEAFADITNTVRARILEIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAI TPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAIADTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI YEDNVPVRLDTVVISTQHAADIDLE+TL PD+REKV+NTVLDDLAH+TLD S+ Sbjct 181 KTQVTIEYEDNVPVRLDTVVISTQHAADIDLERTLTPDLREKVVNTVLDDLAHDTLDTSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+L NPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRLLFNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLFVETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTD+ELPWEQL+KVD+LKRA+ Sbjct 361 IIRDLDLLRPIYAQTAAYGHFGRTDIELPWEQLNKVDELKRAV 403 >gi|118465537|ref|YP_882564.1| S-adenosylmethionine synthetase [Mycobacterium avium 104] gi|158512440|sp|A0QI26.1|METK_MYCA1 RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|118166824|gb|ABK67721.1| S-adenosylmethionine synthetase [Mycobacterium avium 104] Length=403 Score = 755 bits (1949), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/403 (93%), Positives = 388/403 (97%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHE RV Sbjct 61 TTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPE MPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPERMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI +ED+VPVRLDTVVISTQHAADIDLE TL PDIREKVLNTVL+DLAH+TLD S+ Sbjct 181 KTQVTIEFEDDVPVRLDTVVISTQHAADIDLENTLTPDIREKVLNTVLNDLAHDTLDTSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+LVNPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLF+ETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFIETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTDVELPWEQL+KVDDLKRAI Sbjct 361 IIRDLDLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDDLKRAI 403 >gi|335892564|pdb|3S82|A Chain A, Structure Of A S-Adenosylmethionine Synthetase From Mycobacterium Avium gi|335892565|pdb|3S82|B Chain B, Structure Of A S-Adenosylmethionine Synthetase From Mycobacterium Avium Length=407 Score = 754 bits (1948), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/403 (93%), Positives = 388/403 (97%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 5 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 64 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHE RV Sbjct 65 TTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 124 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPE MPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 125 EGAADPLDAQGAGDQGLMFGYAINDTPERMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 184 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI +ED+VPVRLDTVVISTQHAADIDLE TL PDIREKVLNTVL+DLAH+TLD S+ Sbjct 185 KTQVTIEFEDDVPVRLDTVVISTQHAADIDLENTLTPDIREKVLNTVLNDLAHDTLDTSS 244 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+LVNPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 245 TRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 304 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLF+ETFGT T DPVKIEK + EVFDLRPGA Sbjct 305 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFIETFGTATVDPVKIEKIVPEVFDLRPGA 364 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTDVELPWEQL+KVDDLKRAI Sbjct 365 IIRDLDLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDDLKRAI 407 >gi|41407224|ref|NP_960060.1| S-adenosylmethionine synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|254775828|ref|ZP_05217344.1| S-adenosylmethionine synthetase [Mycobacterium avium subsp. avium ATCC 25291] gi|60390054|sp|Q741G5.1|METK_MYCPA RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|41395575|gb|AAS03443.1| MetK [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461629|gb|EGO40494.1| S-adenosylmethionine synthetase [Mycobacterium avium subsp. paratuberculosis S397] Length=403 Score = 754 bits (1946), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/403 (92%), Positives = 388/403 (97%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHE RV Sbjct 61 TTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAI TPE+MPLPIALAHRLSRRLTEVRK+GVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAIKDTPEMMPLPIALAHRLSRRLTEVRKSGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI YED+VPVRLDTVV+STQHAADIDLE TL PDIREKVLNTVLDDLAH+TLD S+ Sbjct 181 KTQVTIEYEDDVPVRLDTVVVSTQHAADIDLENTLTPDIREKVLNTVLDDLAHDTLDTSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+LVNPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLFVETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTDVELPWEQL+KVD+LKRA+ Sbjct 361 IIRDLDLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDELKRAV 403 >gi|254821097|ref|ZP_05226098.1| S-adenosylmethionine synthetase [Mycobacterium intracellulare ATCC 13950] Length=403 Score = 753 bits (1944), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/403 (92%), Positives = 387/403 (97%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVR RIL+IGYDSSDKGFDGA+CGVNIGIGAQSPDIAQGVDTAHE RV Sbjct 61 TTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPE MPLPIALAHRLSRRLTEVRKNGVLPYLRPDG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPERMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI +ED+VPVRLDTVVISTQHAADIDLE TL DIREKVLNTVL+DLAH+TLD S+ Sbjct 181 KTQVTIEFEDDVPVRLDTVVISTQHAADIDLENTLTSDIREKVLNTVLNDLAHDTLDTSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+LVNPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLF+ETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFIETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTDVELPWEQL+KVDDLKRAI Sbjct 361 IIRDLDLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDDLKRAI 403 >gi|15827200|ref|NP_301463.1| S-adenosylmethionine synthetase [Mycobacterium leprae TN] gi|221229678|ref|YP_002503094.1| S-adenosylmethionine synthetase [Mycobacterium leprae Br4923] gi|15214074|sp|Q9CCQ4.1|METK_MYCLE RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|254810922|sp|B8ZUM2.1|METK_MYCLB RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|13092748|emb|CAC30052.1| putative S-adenosylmethionine synthase [Mycobacterium leprae] gi|219932785|emb|CAR70637.1| putative S-adenosylmethionine synthase [Mycobacterium leprae Br4923] Length=403 Score = 749 bits (1935), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/403 (92%), Positives = 386/403 (96%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDS+LDALLA DP SRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSILDALLAEDPCSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T AK AFADI+NTVR RIL+IGYDSSDKGFDGA+CGVNIGIGAQS DIAQGV+TAHE RV Sbjct 61 TLAKTAFADISNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSSDIAQGVNTAHEVRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD+QGAGDQGLMFGYAIN TPELMPLPIALAHRL+RRLTEVRKNGVLPYLR DG Sbjct 121 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLARRLTEVRKNGVLPYLRSDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTIAYEDNVPVRLDTVVISTQHAA +DL+ TL PDIREKVLNTV+DDL+H+TLD S+ Sbjct 181 KTQVTIAYEDNVPVRLDTVVISTQHAAGVDLDATLAPDIREKVLNTVIDDLSHDTLDVSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAER+EVQVAYAIGKAAPVGLFVETFGTE DP KIEKAIGEVFDLRPGA Sbjct 301 WVAKNIVAAGLAERIEVQVAYAIGKAAPVGLFVETFGTEAVDPAKIEKAIGEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTDVELPWEQL+KVDDLKRAI Sbjct 361 IIRDLHLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDDLKRAI 403 >gi|342858674|ref|ZP_08715329.1| S-adenosylmethionine synthetase [Mycobacterium colombiense CECT 3035] gi|342134378|gb|EGT87558.1| S-adenosylmethionine synthetase [Mycobacterium colombiense CECT 3035] Length=403 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/403 (91%), Positives = 383/403 (96%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+AKEAFADITNTVR RIL+IGYDSSDKGFDG+TCGVNIGIG QSPDIAQGVDTAHE RV Sbjct 61 TTAKEAFADITNTVRERILDIGYDSSDKGFDGSTCGVNIGIGKQSPDIAQGVDTAHEHRV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLD QGAGDQGLMFGYAIN TPE MPLPIALAHRLSR+LTEVRKNG LPYLRPDG Sbjct 121 EGAADPLDLQGAGDQGLMFGYAINDTPERMPLPIALAHRLSRKLTEVRKNGTLPYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI YED+VPVRLDTVV+STQHA IDLEKTLDPDIR+ VL TVLD+LAH+TLD+S Sbjct 181 KTQVTIEYEDDVPVRLDTVVVSTQHADGIDLEKTLDPDIRQHVLKTVLDELAHDTLDSSA 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 RVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLAERVEVQVAYAIGKAAPVGLF+ETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFIETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 IIRDL+LLRPIYA TAAYGHFGRTD+ELPWEQL+KVDDLKRAI Sbjct 361 IIRDLDLLRPIYAQTAAYGHFGRTDIELPWEQLNKVDDLKRAI 403 >gi|333990942|ref|YP_004523556.1| s-adenosylmethionine synthetase MetK [Mycobacterium sp. JDM601] gi|333486910|gb|AEF36302.1| s-adenosylmethionine synthetase MetK [Mycobacterium sp. JDM601] Length=403 Score = 739 bits (1908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/403 (90%), Positives = 383/403 (96%), Gaps = 0/403 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 +SEKGRLFTSESVTEGHPDKICDAISDSVLDALLA DPRSRVAVETLVTTGQVHVVGEVT Sbjct 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLADDPRSRVAVETLVTTGQVHVVGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 TSA+EAFA+ITNTVR RIL+IGYDSSDKGFDG TCGVNIGIGAQSPDIAQGVDTAHEARV Sbjct 61 TSAREAFANITNTVRERILDIGYDSSDKGFDGETCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 EGAADPLDSQGAGDQGLMFGYAI TPELMPLPIALAHRLSRRLTEVRKNG L YLRPDG Sbjct 121 EGAADPLDSQGAGDQGLMFGYAIADTPELMPLPIALAHRLSRRLTEVRKNGTLDYLRPDG 180 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI YED+VP RLDTVVISTQHA IDL KTLDPD+RE V++TVL +L HETLD+S+ Sbjct 181 KTQVTIEYEDDVPTRLDTVVISTQHADGIDLVKTLDPDLREHVISTVLAELGHETLDSSS 240 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+L+NPTGKFV+GGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 241 TRILINPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN+VAAGLA+RVEVQVAYAIGKAAPVGLF+ETFGT T DPVKIEK + EVFDLRPGA Sbjct 301 WVAKNIVAAGLAQRVEVQVAYAIGKAAPVGLFIETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 I+RDL+LLRPIYAPTAAYGHFGRTD+ELPWEQLDKVDDLKRAI Sbjct 361 IVRDLDLLRPIYAPTAAYGHFGRTDIELPWEQLDKVDDLKRAI 403 >gi|108799340|ref|YP_639537.1| S-adenosylmethionine synthetase [Mycobacterium sp. MCS] gi|119868456|ref|YP_938408.1| S-adenosylmethionine synthetase [Mycobacterium sp. KMS] gi|126434998|ref|YP_001070689.1| S-adenosylmethionine synthetase [Mycobacterium sp. JLS] 6 more sequence titles Length=402 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/400 (89%), Positives = 371/400 (93%), Gaps = 0/400 (0%) Query 4 KGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSA 63 KGRLFTSESVTEGHPDKICDAISDSVLD+LLA DPRSRVAVETLVTTGQVHVVGEVTTSA Sbjct 3 KGRLFTSESVTEGHPDKICDAISDSVLDSLLAQDPRSRVAVETLVTTGQVHVVGEVTTSA 62 Query 64 KEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGA 123 KEAFADITNTVR RILE+GYDSSDKGFDG TCGVNIGIGAQSPDIAQGVDTAHE RVEGA Sbjct 63 KEAFADITNTVRHRILEVGYDSSDKGFDGTTCGVNIGIGAQSPDIAQGVDTAHETRVEGA 122 Query 124 ADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQ 183 DPLD QGAGDQGLMFGYAI TPELMPLPIALAHRL+RRLTEVRKNGVL YLRPDGKTQ Sbjct 123 GDPLDLQGAGDQGLMFGYAIKDTPELMPLPIALAHRLARRLTEVRKNGVLDYLRPDGKTQ 182 Query 184 VTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRV 243 VT+ Y+ PVRLDTVV+STQHA IDLE TL PDIREKV+NTVL DL H+++D S R+ Sbjct 183 VTVQYDGVTPVRLDTVVLSTQHAEGIDLEGTLTPDIREKVVNTVLSDLNHDSMDTSDFRL 242 Query 244 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 303 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA Sbjct 243 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 302 Query 304 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIR 363 KNVVAAGLA+RVEVQVAYAIGKAAPVGLFVETFGTET DP KIEKAI EVFDLRPGAI+R Sbjct 303 KNVVAAGLADRVEVQVAYAIGKAAPVGLFVETFGTETVDPAKIEKAITEVFDLRPGAIVR 362 Query 364 DLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 DL+LLRPIYAPTAAYGHFGRTD++LPWE+ DK D LK A+ Sbjct 363 DLDLLRPIYAPTAAYGHFGRTDIDLPWERTDKADALKTAV 402 >gi|120403654|ref|YP_953483.1| S-adenosylmethionine synthetase [Mycobacterium vanbaalenii PYR-1] gi|158513015|sp|A1T8H7.1|METK_MYCVP RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|119956472|gb|ABM13477.1| methionine adenosyltransferase [Mycobacterium vanbaalenii PYR-1] Length=402 Score = 711 bits (1835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/398 (88%), Positives = 369/398 (93%), Gaps = 0/398 (0%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDSVLDALLA DP+SRVAVETLVTTGQVHVVGEVTT+AK Sbjct 5 RLFTSESVTEGHPDKICDAISDSVLDALLADDPKSRVAVETLVTTGQVHVVGEVTTTAKA 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 AFADITNTVR RILEIGYD SDKGFDG TCGVNIGIG QSPDIAQGVDTAHE RVEGAAD Sbjct 65 AFADITNTVRERILEIGYDHSDKGFDGLTCGVNIGIGKQSPDIAQGVDTAHETRVEGAAD 124 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 PLDSQGAGDQGLMFGYAI TPELMPLPIALAHRLSR+LTEVRKNG L YLRPDGKTQVT Sbjct 125 PLDSQGAGDQGLMFGYAIADTPELMPLPIALAHRLSRKLTEVRKNGTLDYLRPDGKTQVT 184 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 + Y+ PVRLDTVV+STQHA IDLE L P+I++ V++ VL +L H+TLD S R+LV Sbjct 185 VQYDGTTPVRLDTVVLSTQHADGIDLESQLAPEIKQHVIDAVLTELGHDTLDTSAPRILV 244 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 245 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 304 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VVAAGLA+RVEVQVAYAIGKAAPVGLFVETFG+ET DPVKI+KAIGEVFDLRPGAI+RDL Sbjct 305 VVAAGLAQRVEVQVAYAIGKAAPVGLFVETFGSETVDPVKIQKAIGEVFDLRPGAIVRDL 364 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 +LLRPIYAPTAAYGHFGRTD+ELPWEQLDKVDDLK A+ Sbjct 365 DLLRPIYAPTAAYGHFGRTDIELPWEQLDKVDDLKAAV 402 >gi|145224319|ref|YP_001134997.1| S-adenosylmethionine synthetase [Mycobacterium gilvum PYR-GCK] gi|315444651|ref|YP_004077530.1| methionine adenosyltransferase [Mycobacterium sp. Spyr1] gi|189081721|sp|A4TBZ0.1|METK_MYCGI RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|145216805|gb|ABP46209.1| methionine adenosyltransferase [Mycobacterium gilvum PYR-GCK] gi|315262954|gb|ADT99695.1| methionine adenosyltransferase [Mycobacterium sp. Spyr1] Length=402 Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/400 (87%), Positives = 371/400 (93%), Gaps = 0/400 (0%) Query 4 KGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSA 63 + RLFTSESVTEGHPDKICDAISDSVLDALLA DP+SRVAVETLVTTGQVHVVGEVTT+A Sbjct 3 EARLFTSESVTEGHPDKICDAISDSVLDALLAGDPKSRVAVETLVTTGQVHVVGEVTTNA 62 Query 64 KEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGA 123 KEAFADITNTVR RILEIGYD SDKGFDG TCGVNIGIG QSPDIAQGVDTAHE RV GA Sbjct 63 KEAFADITNTVRERILEIGYDHSDKGFDGETCGVNIGIGRQSPDIAQGVDTAHETRVGGA 122 Query 124 ADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQ 183 ADPLDSQGAGDQGLMFGYAI TPELMPLPIALAHRLSR+LTEVRKNG L YLRPDGKTQ Sbjct 123 ADPLDSQGAGDQGLMFGYAIADTPELMPLPIALAHRLSRKLTEVRKNGTLDYLRPDGKTQ 182 Query 184 VTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRV 243 VT+ Y+ PVRLDTVV+STQHA I+L+ L+P+I++ V++ VL +L H+TLD S R+ Sbjct 183 VTVQYDGTTPVRLDTVVLSTQHADGIELDSQLEPEIKQHVIDAVLTELGHQTLDTSNPRI 242 Query 244 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 303 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA Sbjct 243 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 302 Query 304 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIR 363 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFG+ET DPVKIEKAIGEVFDLRPGAI+R Sbjct 303 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSETVDPVKIEKAIGEVFDLRPGAIVR 362 Query 364 DLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 DL+LLRPIYAPTAAYGHFGRTD+ELPWEQL+KVDDLK A+ Sbjct 363 DLDLLRPIYAPTAAYGHFGRTDIELPWEQLNKVDDLKSAV 402 >gi|118468007|ref|YP_887371.1| S-adenosylmethionine synthetase [Mycobacterium smegmatis str. MC2 155] gi|48428371|sp|Q7WYN1.1|METK_MYCSM RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|158512468|sp|A0QWT3.1|METK_MYCS2 RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|32330659|gb|AAP79876.1| methionine adenosyltransferase [Mycobacterium smegmatis] gi|118169294|gb|ABK70190.1| S-adenosylmethionine synthetase [Mycobacterium smegmatis str. MC2 155] Length=399 Score = 700 bits (1806), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/400 (87%), Positives = 364/400 (91%), Gaps = 3/400 (0%) Query 4 KGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSA 63 KGRLFTSESVTEGHPDKICDAISDSVLDALL DP+SRVAVETLVTTGQVHV GEVTT+A Sbjct 3 KGRLFTSESVTEGHPDKICDAISDSVLDALLEQDPKSRVAVETLVTTGQVHVAGEVTTTA 62 Query 64 KEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGA 123 +ADI VR RIL+IGYDSS KGFDGA+CGVN+ IGAQSPDIAQGVDTAHE RVEG Sbjct 63 ---YADIPKIVRDRILDIGYDSSTKGFDGASCGVNVAIGAQSPDIAQGVDTAHETRVEGK 119 Query 124 ADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQ 183 ADPLD QGAGDQGLMFGYAI TPELMPLPIALAHRL+RRLTEVRKNGVL YLRPDGKTQ Sbjct 120 ADPLDLQGAGDQGLMFGYAIGDTPELMPLPIALAHRLARRLTEVRKNGVLDYLRPDGKTQ 179 Query 184 VTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRV 243 VTI Y+ PVRLDTVV+STQHA IDLE TL PDIREKV+NTVL DL HETLD S R+ Sbjct 180 VTIQYDGTTPVRLDTVVLSTQHADGIDLEGTLTPDIREKVVNTVLADLGHETLDTSDYRL 239 Query 244 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 303 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA Sbjct 240 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 299 Query 304 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIR 363 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFG+ET DP KIEKAIGEVFDLRP AI+R Sbjct 300 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSETVDPAKIEKAIGEVFDLRPAAIVR 359 Query 364 DLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 DL+LLRPIYAPTAAYGHFGRTD+ELPWEQ +KVDDLK AI Sbjct 360 DLDLLRPIYAPTAAYGHFGRTDIELPWEQTNKVDDLKSAI 399 >gi|169629904|ref|YP_001703553.1| S-adenosylmethionine synthetase [Mycobacterium abscessus ATCC 19977] gi|169241871|emb|CAM62899.1| Probable S-adenosylmethionine synthetase (Methionine adenosyltransferase) [Mycobacterium abscessus] Length=388 Score = 668 bits (1724), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/391 (85%), Positives = 353/391 (91%), Gaps = 3/391 (0%) Query 13 VTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITN 72 +TEGHPDKICDAISDS+LDA+LA DP+SRVAVETLVTTGQVHV GEVTTSA + DI + Sbjct 1 MTEGHPDKICDAISDSILDAMLAQDPKSRVAVETLVTTGQVHVAGEVTTSA---YVDIPH 57 Query 73 TVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGA 132 VR R+LEIGYDSS KGFDG +CGVN+ IGAQSPDIAQGVDTAHEARVEGAADPLD+QGA Sbjct 58 IVRERVLEIGYDSSSKGFDGNSCGVNVAIGAQSPDIAQGVDTAHEARVEGAADPLDAQGA 117 Query 133 GDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNV 192 GDQGLMFGYAIN TPELMPLPIALAHRLSRRLTEVRK+G+LPYLRPDGKTQVTI Y+ N Sbjct 118 GDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKDGLLPYLRPDGKTQVTIEYDGNK 177 Query 193 PVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFV 252 VRLDTVV+STQHAADIDLE L PDIREKV+ VLD+L + LD S R+LVNPTGKFV Sbjct 178 AVRLDTVVLSTQHAADIDLENLLTPDIREKVVQVVLDELNQDGLDISDYRLLVNPTGKFV 237 Query 253 LGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLA 312 LGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLA Sbjct 238 LGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLA 297 Query 313 ERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIY 372 +R EVQVAYAIGKAAPVGLFV+TFGT T D KIEKAI EVFDLRPGAIIRDL+LLRPIY Sbjct 298 DRAEVQVAYAIGKAAPVGLFVDTFGTATVDQAKIEKAINEVFDLRPGAIIRDLDLLRPIY 357 Query 373 APTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 A TAAYGHFGRTDVELPWEQ D+VD LK AI Sbjct 358 AQTAAYGHFGRTDVELPWEQTDRVDALKAAI 388 >gi|54025583|ref|YP_119825.1| S-adenosylmethionine synthetase [Nocardia farcinica IFM 10152] gi|60389915|sp|Q5YTN0.1|METK_NOCFA RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|54017091|dbj|BAD58461.1| putative S-adenosylmethionine synthetase [Nocardia farcinica IFM 10152] Length=404 Score = 650 bits (1676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/398 (83%), Positives = 350/398 (88%), Gaps = 4/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDALLA DPRSRVAVETLVTTGQVHV GEVTTSA Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDALLAEDPRSRVAVETLVTTGQVHVAGEVTTSA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +ADI VR ++LEIGYDSS KGFDG +CGVNI IGAQSPDIAQGVDT+HEARV G D Sbjct 65 -YADIPRIVREKVLEIGYDSSAKGFDGNSCGVNIAIGAQSPDIAQGVDTSHEARVGGTDD 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 + QGAGDQGLMFGYA TPELMPLPIALAHRLSR+LTEVRK GVLPYLRPDGKTQVT Sbjct 124 EIAKQGAGDQGLMFGYATTDTPELMPLPIALAHRLSRKLTEVRKTGVLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHET-LDASTVRVL 244 I Y+ + PVRLDTVVISTQHAADIDL+ L PDIREKV++ VL DL + LD S +R+L Sbjct 184 IEYDGDRPVRLDTVVISTQHAADIDLDNLLAPDIREKVVDAVLADLDLPSPLDTSDIRLL 243 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 244 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 303 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 NVVAAGL+ERVEVQVAYAIGKAAPVGLFVETFGTE DP +I AI EVFDLRPGAIIRD Sbjct 304 NVVAAGLSERVEVQVAYAIGKAAPVGLFVETFGTEKVDPARIAAAITEVFDLRPGAIIRD 363 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 L+LLRPIYAPTAAYGHFGRTD++LPWE D+ D L+ A Sbjct 364 LDLLRPIYAPTAAYGHFGRTDIDLPWEHTDRADKLRAA 401 >gi|226306498|ref|YP_002766458.1| S-adenosylmethionine synthetase [Rhodococcus erythropolis PR4] gi|229493491|ref|ZP_04387276.1| methionine adenosyltransferase [Rhodococcus erythropolis SK121] gi|259491820|sp|C0ZZD4.1|METK_RHOE4 RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|226185615|dbj|BAH33719.1| S-adenosylmethionine synthetase [Rhodococcus erythropolis PR4] gi|229319452|gb|EEN85288.1| methionine adenosyltransferase [Rhodococcus erythropolis SK121] Length=404 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/398 (81%), Positives = 350/398 (88%), Gaps = 4/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDALL DPR+RVAVETLVTTGQVHV GEVTT+A Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDALLTQDPRARVAVETLVTTGQVHVAGEVTTTA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +ADI VR +LEIGYDSS KGFDG +CGVN+ IGAQSP+IAQGVD +HEARV+G +D Sbjct 65 -YADIPKIVRDTVLEIGYDSSAKGFDGNSCGVNVAIGAQSPEIAQGVDHSHEARVDGISD 123 Query 126 -PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQV 184 +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLTEVRK+GVLPYLRPDGKTQV Sbjct 124 DEIDRQGAGDQGLMFGYATTDTPELMPLPIALAHRLSRRLTEVRKSGVLPYLRPDGKTQV 183 Query 185 TIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVL 244 TI Y+ + VRLDTVVISTQHAADIDL+ L PD+REKVL++VL D+ LD S VR+L Sbjct 184 TIEYDGDKAVRLDTVVISTQHAADIDLDNLLTPDLREKVLHSVLTDVNLTDLDTSDVRLL 243 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 244 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 303 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP +I+KAI E+FDLRPGAIIRD Sbjct 304 NAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEKTDPARIQKAITEIFDLRPGAIIRD 363 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 L+LLRPIYA TAAYGHFGRTD++LPWE D+ D L+ A Sbjct 364 LDLLRPIYAQTAAYGHFGRTDIDLPWESTDRADKLRSA 401 >gi|317505994|ref|ZP_07963826.1| methionine adenosyltransferase [Segniliparus rugosus ATCC BAA-974] gi|316255770|gb|EFV15008.1| methionine adenosyltransferase [Segniliparus rugosus ATCC BAA-974] Length=403 Score = 641 bits (1654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/403 (81%), Positives = 352/403 (88%), Gaps = 4/403 (0%) Query 1 VSEKG-RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEV 59 +S+ G RLFTSESVTEGHPDKICDAISDS+LDALLA DP SRVAVETLVTTGQVHV GEV Sbjct 1 MSQAGWRLFTSESVTEGHPDKICDAISDSILDALLAQDPASRVAVETLVTTGQVHVAGEV 60 Query 60 TTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEAR 119 TT +A+ADI + VR +IL+IGYDSS KGFDG +CGVNI IGAQSPDIAQGVDTA+E+R Sbjct 61 TT---KAYADIPHIVREKILDIGYDSSSKGFDGNSCGVNIAIGAQSPDIAQGVDTAYESR 117 Query 120 VEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPD 179 V+G D +D QGAGDQGLMFG+A TPELMPLPI+LAHRLSRRLTEVRK GVLPYLRPD Sbjct 118 VDGLLDDIDKQGAGDQGLMFGFATRDTPELMPLPISLAHRLSRRLTEVRKTGVLPYLRPD 177 Query 180 GKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAS 239 GKTQVTI Y+ + VR+DTVV+STQHAADIDL+ L PDIR+ V+ VL A + LD S Sbjct 178 GKTQVTIEYDGDKAVRVDTVVVSTQHAADIDLDNLLAPDIRKAVVEPVLQGAAADGLDVS 237 Query 240 TVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAM 299 R+LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGG+ARHGGGAFSGKDPSKVDRSAAYAM Sbjct 238 DFRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGFARHGGGAFSGKDPSKVDRSAAYAM 297 Query 300 RWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPG 359 RWVAKNVVAAGLA+RVE QVAYAIGKAAPVGLFVETFGTE DPVKI A+ EVFDLRP Sbjct 298 RWVAKNVVAAGLADRVETQVAYAIGKAAPVGLFVETFGTEHVDPVKIRAALSEVFDLRPA 357 Query 360 AIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 AIIRDL+LLRPIYAPTAAYGHFGRTDVELPWEQ D+ D LK A Sbjct 358 AIIRDLDLLRPIYAPTAAYGHFGRTDVELPWEQTDRADALKAA 400 >gi|296394690|ref|YP_003659574.1| S-adenosylmethionine synthetase [Segniliparus rotundus DSM 44985] gi|296181837|gb|ADG98743.1| S-adenosylmethionine synthetase [Segniliparus rotundus DSM 44985] Length=404 Score = 639 bits (1648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/404 (80%), Positives = 350/404 (87%), Gaps = 4/404 (0%) Query 1 VSEKG-RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEV 59 +S+ G RLFTSESVTEGHPDKICDAISDS+LDALLA DP SRVAVETLVTTGQVHV GEV Sbjct 1 MSQAGWRLFTSESVTEGHPDKICDAISDSILDALLAQDPASRVAVETLVTTGQVHVAGEV 60 Query 60 TTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEAR 119 TT +A+ADI + VR RIL+IGYDSS KGFDG +CGVNI IGAQSPDIAQGVDTA+E+R Sbjct 61 TT---KAYADIPHIVRERILDIGYDSSSKGFDGNSCGVNIAIGAQSPDIAQGVDTAYESR 117 Query 120 VEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPD 179 V+G D +D QGAGDQGLMFG+A TPELMPLPI+LAHRLSRRLTEVRK GVLPYLRPD Sbjct 118 VDGRLDDIDKQGAGDQGLMFGFATRDTPELMPLPISLAHRLSRRLTEVRKTGVLPYLRPD 177 Query 180 GKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAS 239 GKTQVTI Y+ + VR+DTVV+STQHAADIDL+ L PDIR+ V+ VL A LD S Sbjct 178 GKTQVTIEYDGDRAVRVDTVVVSTQHAADIDLDNLLAPDIRKSVVEPVLQTAAANGLDVS 237 Query 240 TVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAM 299 R+LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGG+ARHGGGAFSGKDPSKVDRSAAYAM Sbjct 238 DYRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYAM 297 Query 300 RWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPG 359 RWVAKNVVAAGLA++VE QVAYAIGKAAPVGLFVETFGTE DPVKI A+ EVFDLRP Sbjct 298 RWVAKNVVAAGLADKVETQVAYAIGKAAPVGLFVETFGTEHVDPVKIRAALSEVFDLRPA 357 Query 360 AIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 AIIRDL LLRPIYA TAAYGHFGRTDVELPWEQ D+ D LK A+ Sbjct 358 AIIRDLGLLRPIYAQTAAYGHFGRTDVELPWEQTDRADALKAAV 401 >gi|296140274|ref|YP_003647517.1| S-adenosylmethionine synthetase [Tsukamurella paurometabola DSM 20162] gi|296028408|gb|ADG79178.1| S-adenosylmethionine synthetase [Tsukamurella paurometabola DSM 20162] Length=407 Score = 637 bits (1642), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 317/395 (81%), Positives = 346/395 (88%), Gaps = 3/395 (0%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDALL DP SRVAVETLVTTGQVHV GEVTTSA Sbjct 11 RLFTSESVTEGHPDKICDAISDSILDALLTEDPTSRVAVETLVTTGQVHVAGEVTTSA-- 68 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +ADI + VR ++LEIGYDSS KGFDG +CGVNI IGAQSP+IAQGVD A+E RV+GA D Sbjct 69 -WADIPHIVRDKVLEIGYDSSAKGFDGNSCGVNIAIGAQSPEIAQGVDRAYEHRVDGADD 127 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 +D+QGAGDQGLMFGYA + TPELMPLPI+LAHRLSRRLTEVRKNG LPYLRPDGKTQVT Sbjct 128 EIDAQGAGDQGLMFGYACSDTPELMPLPISLAHRLSRRLTEVRKNGTLPYLRPDGKTQVT 187 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y PVRLDTVVIS+QHAADID++ L PD+RE VL +V+ DL +LD S VR+LV Sbjct 188 IEYAGEQPVRLDTVVISSQHAADIDIDGMLTPDLREHVLGSVIADLNLPSLDTSDVRLLV 247 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 248 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 307 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VAAGLAER+EVQVAYAIGKAAPVGLFVETFGTE DP KI++AI EVFDLRP AII DL Sbjct 308 AVAAGLAERIEVQVAYAIGKAAPVGLFVETFGTEQVDPQKIQQAITEVFDLRPRAIINDL 367 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLK 400 +LLRPIYAPTAAYGHFGRTD++LPWE + D L+ Sbjct 368 DLLRPIYAPTAAYGHFGRTDIDLPWEHTGRADALR 402 >gi|256377203|ref|YP_003100863.1| S-adenosylmethionine synthetase [Actinosynnema mirum DSM 43827] gi|255921506|gb|ACU37017.1| S-adenosylmethionine synthetase [Actinosynnema mirum DSM 43827] Length=401 Score = 632 bits (1630), Expect = 3e-179, Method: Compositional matrix adjust. Identities = 318/398 (80%), Positives = 341/398 (86%), Gaps = 6/398 (1%) Query 5 GRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAK 64 GRLFTSESVTEGHPDKICDAISDS+LDALLA DP SRVAVETLVTTGQVHV GEVTT Sbjct 7 GRLFTSESVTEGHPDKICDAISDSILDALLAKDPTSRVAVETLVTTGQVHVAGEVTT--- 63 Query 65 EAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAA 124 EA+ DI + VR +ILEIGYDSS KGFDG +CGVN+ IGAQSPDIAQGVDTA+E R A Sbjct 64 EAYVDIPSIVREKILEIGYDSSAKGFDGHSCGVNVAIGAQSPDIAQGVDTAYEQRTGDAG 123 Query 125 DPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQV 184 D +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLT VRK+G +PYLRPDGKTQV Sbjct 124 DDIDQQGAGDQGLMFGYACTDTPELMPLPIALAHRLSRRLTAVRKDGSVPYLRPDGKTQV 183 Query 185 TIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVL 244 TI Y + PVRLDTVV+STQHA IDLE+ L D+RE VL ++ L LD S VR+L Sbjct 184 TIEYAGDQPVRLDTVVVSTQHADGIDLEQLLGVDVREYVLTPEIEGLG---LDTSNVRLL 240 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTG+FVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 241 VNPTGRFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 300 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA R+EVQVAYAIGKAAPVGLFVETFGTET DP KI++AI EVFDLRP AIIRD Sbjct 301 NAVAAGLATRIEVQVAYAIGKAAPVGLFVETFGTETVDPTKIQQAIAEVFDLRPAAIIRD 360 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 LNLLRPIYAPTAAYGHFGRTDVELPWE + DDL+ A Sbjct 361 LNLLRPIYAPTAAYGHFGRTDVELPWEDTSRADDLRAA 398 >gi|262202275|ref|YP_003273483.1| S-adenosylmethionine synthetase [Gordonia bronchialis DSM 43247] gi|262085622|gb|ACY21590.1| S-adenosylmethionine synthetase [Gordonia bronchialis DSM 43247] Length=403 Score = 632 bits (1629), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 313/397 (79%), Positives = 344/397 (87%), Gaps = 3/397 (0%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDSVLDA+L DP++RVAVETLVTTGQVHV GEVTT+A Sbjct 7 RLFTSESVTEGHPDKICDAISDSVLDAILTEDPKARVAVETLVTTGQVHVAGEVTTTA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 + DI VR +ILEIGYDSS KGFDGA+CGVN+ IGAQSPDIA GV +HE+R + D Sbjct 65 -YVDIPGIVRQKILEIGYDSSTKGFDGASCGVNVAIGAQSPDIAGGVFNSHESRSGISED 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 +DSQGAGDQGLMFG+A N TPELMPLPIALAHRLSR+LTEVRK+GVLPYLRPDGKTQVT Sbjct 124 EIDSQGAGDQGLMFGFATNETPELMPLPIALAHRLSRKLTEVRKSGVLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y+ + PVRLDTVV+STQHAADIDLE L PDIR +V+ VL DL TLD S R+LV Sbjct 184 IEYDGDKPVRLDTVVLSTQHAADIDLENMLTPDIRTEVVEAVLADLEVATLDTSGYRLLV 243 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 244 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 303 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP IE+ I E FDLRP AIIRDL Sbjct 304 AVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEKVDPAVIERVISENFDLRPLAIIRDL 363 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 +LLRPIYAPTAAYGHFGRTD++LPWE+ D+ + L+ A Sbjct 364 DLLRPIYAPTAAYGHFGRTDIDLPWERTDRAEKLRAA 400 >gi|111024108|ref|YP_707080.1| S-adenosylmethionine synthetase [Rhodococcus jostii RHA1] gi|123144025|sp|Q0S0L4.1|METK_RHOSR RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|110823638|gb|ABG98922.1| methionine adenosyltransferase [Rhodococcus jostii RHA1] Length=404 Score = 630 bits (1625), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 315/404 (78%), Positives = 350/404 (87%), Gaps = 5/404 (1%) Query 1 VSEKG-RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEV 59 +S+ G RLFTSESVTEGHPDKICDAISDS+LDALL DPR+RVAVETLVTTGQVHV GEV Sbjct 1 MSQSGSRLFTSESVTEGHPDKICDAISDSILDALLTDDPRARVAVETLVTTGQVHVAGEV 60 Query 60 TTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEAR 119 TTSA +ADI VR +LEIGYDSS KGFDG +CGVN+ IGAQSP+IAQGVD +HE R Sbjct 61 TTSA---YADIPKIVRDTVLEIGYDSSAKGFDGNSCGVNVAIGAQSPEIAQGVDHSHEVR 117 Query 120 V-EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRP 178 E + D +D QGAGDQGLMFG+A TPELMPLPIALAHRLSRRLTEVRK+GVLPYLRP Sbjct 118 TGELSDDEIDRQGAGDQGLMFGFATTDTPELMPLPIALAHRLSRRLTEVRKSGVLPYLRP 177 Query 179 DGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDA 238 DGKTQVTI Y+ + VRLDTVVISTQHAADIDL+ L PD+REKVL +VL ++ LD Sbjct 178 DGKTQVTIEYDGDKAVRLDTVVISTQHAADIDLDNLLTPDLREKVLGSVLAEIDMPELDV 237 Query 239 STVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYA 298 S +R+LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYA Sbjct 238 SDIRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYA 297 Query 299 MRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRP 358 MRWVAKN VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP +I++AI E FDLRP Sbjct 298 MRWVAKNAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEKTDPARIQQAITETFDLRP 357 Query 359 GAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 GAIIRDL+LLRPIYA TAAYGHFGRTD++LPWE +D+ + L+ A Sbjct 358 GAIIRDLDLLRPIYAQTAAYGHFGRTDIDLPWESIDRAEKLRAA 401 >gi|312139575|ref|YP_004006911.1| s-adenosylmethionine synthetase [Rhodococcus equi 103S] gi|311888914|emb|CBH48227.1| S-adenosylmethionine synthetase [Rhodococcus equi 103S] Length=403 Score = 630 bits (1624), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 319/398 (81%), Positives = 345/398 (87%), Gaps = 5/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDA+L DPRSRVAVETLVTTGQVHV GEVTTSA Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDAMLEKDPRSRVAVETLVTTGQVHVAGEVTTSA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 + DI VR ++LEIGYDSS KGFDG +CGVNI IGAQSP+IAQGVD +HEARV G AD Sbjct 65 -YVDIPKIVRDKVLEIGYDSSAKGFDGNSCGVNIAIGAQSPEIAQGVDHSHEARVGGLAD 123 Query 126 -PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQV 184 +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLTEVRK GVLPYLRPDGKTQV Sbjct 124 DEIDRQGAGDQGLMFGYACTDTPELMPLPIALAHRLSRRLTEVRKTGVLPYLRPDGKTQV 183 Query 185 TIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVL 244 TI Y+ + PVRLDTVVISTQHAADIDL+ L PD+REKVL VL +L LD + VR+L Sbjct 184 TIEYDGDRPVRLDTVVISTQHAADIDLDNLLTPDLREKVLGHVLSELTIP-LDTADVRLL 242 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 243 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 302 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA+R+EVQVAYAIGKAAPVGLFVE FGTE D I++AI EVFDLRPGAIIRD Sbjct 303 NAVAAGLADRIEVQVAYAIGKAAPVGLFVEAFGTEKVDIATIQQAISEVFDLRPGAIIRD 362 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 L+LLRPIYA TAAYGHFGRTDV+LPWE+ D+ + L+ A Sbjct 363 LDLLRPIYADTAAYGHFGRTDVDLPWERTDRAEKLRAA 400 >gi|226366348|ref|YP_002784131.1| S-adenosylmethionine synthetase [Rhodococcus opacus B4] gi|254810923|sp|C1B4J7.1|METK_RHOOB RecName: Full=S-adenosylmethionine synthase; Short=AdoMet synthase; AltName: Full=MAT; AltName: Full=Methionine adenosyltransferase gi|226244838|dbj|BAH55186.1| S-adenosylmethionine synthetase [Rhodococcus opacus B4] Length=404 Score = 629 bits (1622), Expect = 3e-178, Method: Compositional matrix adjust. Identities = 314/404 (78%), Positives = 350/404 (87%), Gaps = 5/404 (1%) Query 1 VSEKG-RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEV 59 +S+ G RLFTSESVTEGHPDKICDAISDS+LDALL DPR+RVAVETLVTTGQVHV GEV Sbjct 1 MSQSGSRLFTSESVTEGHPDKICDAISDSILDALLTDDPRARVAVETLVTTGQVHVAGEV 60 Query 60 TTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEAR 119 TT+A +ADI VR +LEIGYDSS KGFDG +CGVN+ IGAQSP+IAQGVD +HE R Sbjct 61 TTTA---YADIPKIVRDTVLEIGYDSSAKGFDGNSCGVNVAIGAQSPEIAQGVDHSHEVR 117 Query 120 V-EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRP 178 E + D +D QGAGDQGLMFG+A TPELMPLPIALAHRLSRRLTEVRK+GVLPYLRP Sbjct 118 TGELSDDEIDRQGAGDQGLMFGFATTDTPELMPLPIALAHRLSRRLTEVRKSGVLPYLRP 177 Query 179 DGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDA 238 DGKTQVTI Y+ + VRLDTVVISTQHAADIDL+ L PD+REKVL +VL ++ LD Sbjct 178 DGKTQVTIEYDGDKAVRLDTVVISTQHAADIDLDNLLTPDLREKVLGSVLAEIDMPELDV 237 Query 239 STVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYA 298 S +R+LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYA Sbjct 238 SDIRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYA 297 Query 299 MRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRP 358 MRWVAKN VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP +I++AI E FDLRP Sbjct 298 MRWVAKNAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEKTDPARIQQAITETFDLRP 357 Query 359 GAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 GAIIRDL+LLRPIYA TAAYGHFGRTD++LPWE +D+ + L+ A Sbjct 358 GAIIRDLDLLRPIYAQTAAYGHFGRTDIDLPWESIDRAEKLRAA 401 >gi|325672541|ref|ZP_08152237.1| methionine adenosyltransferase [Rhodococcus equi ATCC 33707] gi|325556418|gb|EGD26084.1| methionine adenosyltransferase [Rhodococcus equi ATCC 33707] Length=403 Score = 627 bits (1616), Expect = 1e-177, Method: Compositional matrix adjust. Identities = 318/398 (80%), Positives = 344/398 (87%), Gaps = 5/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDA+L DPRSRVAVETLVTTGQVHV GEVTTSA Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDAMLEKDPRSRVAVETLVTTGQVHVAGEVTTSA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 + DI VR ++LEIGYDSS KGFDG +CGVNI IGAQSP+IAQGVD +HEARV G AD Sbjct 65 -YVDIPKIVRDKVLEIGYDSSAKGFDGNSCGVNIAIGAQSPEIAQGVDHSHEARVGGLAD 123 Query 126 -PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQV 184 +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLTEVRK GVLPYLRPDGKTQV Sbjct 124 DEIDRQGAGDQGLMFGYACTDTPELMPLPIALAHRLSRRLTEVRKTGVLPYLRPDGKTQV 183 Query 185 TIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVL 244 TI Y+ + PVRLDTVVISTQHAADIDL+ L PD+REKVL VL +L LD + VR+L Sbjct 184 TIEYDGDRPVRLDTVVISTQHAADIDLDNLLTPDLREKVLGHVLSELTIP-LDTADVRLL 242 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 243 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 302 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA+R+EVQVAYAIGKAAPVGLFVE FGTE D I++AI EVFDLRP AIIRD Sbjct 303 NAVAAGLADRIEVQVAYAIGKAAPVGLFVEAFGTEKVDIATIQQAISEVFDLRPRAIIRD 362 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 L+LLRPIYA TAAYGHFGRTDV+LPWE+ D+ + L+ A Sbjct 363 LDLLRPIYADTAAYGHFGRTDVDLPWERTDRAEKLRAA 400 >gi|257055595|ref|YP_003133427.1| methionine adenosyltransferase [Saccharomonospora viridis DSM 43017] gi|256585467|gb|ACU96600.1| methionine adenosyltransferase [Saccharomonospora viridis DSM 43017] Length=400 Score = 625 bits (1613), Expect = 3e-177, Method: Compositional matrix adjust. Identities = 313/397 (79%), Positives = 345/397 (87%), Gaps = 6/397 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICD+ISDS+LDALLAADPRSRVAVETL+TTGQVH+VGEVTT E Sbjct 7 RLFTSESVTEGHPDKICDSISDSILDALLAADPRSRVAVETLITTGQVHIVGEVTT---E 63 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 A+ADI VR R+LEIGYDSS KGFDGA+CGVN+ I +QSPDIAQGVD+A+EAR+E A D Sbjct 64 AYADIPTIVRDRVLEIGYDSSAKGFDGASCGVNVAIDSQSPDIAQGVDSAYEARLENALD 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 LD QGAGDQGLMFGYA + TPELMPLPIALAHR +RRLT VRK GVLPYLRPDGKTQVT Sbjct 124 ELDRQGAGDQGLMFGYACSDTPELMPLPIALAHRFARRLTAVRKEGVLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y+ + PVRLDTVVIS+QHA IDLE L D+ E V+ VL ++ E D R+L+ Sbjct 184 IEYDGDRPVRLDTVVISSQHAEGIDLEGMLAADLAEHVVTPVLHEMDWEQED---TRLLI 240 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 241 NPTGRFVVGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 300 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VVAAGLA RVEVQVAYAIGKAAPVGLFVETFGTE DP KI+ AI EVFDLRP AIIRDL Sbjct 301 VVAAGLAGRVEVQVAYAIGKAAPVGLFVETFGTEKVDPAKIQAAITEVFDLRPAAIIRDL 360 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 +LLRPIYAPTAAYGHFGRTD++LPWE+ D+VD L+ A Sbjct 361 DLLRPIYAPTAAYGHFGRTDLDLPWERTDRVDALRSA 397 >gi|325001020|ref|ZP_08122132.1| S-adenosylmethionine synthetase [Pseudonocardia sp. P1] Length=400 Score = 624 bits (1610), Expect = 7e-177, Method: Compositional matrix adjust. Identities = 313/398 (79%), Positives = 339/398 (86%), Gaps = 6/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISD+VLDA+LA DP SRVAVET+VTTGQVHV GEVTT+A Sbjct 7 RLFTSESVTEGHPDKICDAISDTVLDAMLAQDPSSRVAVETMVTTGQVHVAGEVTTNA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 + +I VR RILEIGYDSS KGFDGA+CGVNI IGAQSPDIAQGVDTA+E RVE A D Sbjct 65 -YVEIPQLVRDRILEIGYDSSAKGFDGASCGVNIAIGAQSPDIAQGVDTAYEKRVESAED 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 + QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLTEVRKNG LPYLR DGKTQVT Sbjct 124 EIAKQGAGDQGLMFGYACEDTPELMPLPIALAHRLSRRLTEVRKNGTLPYLRADGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I YE + P RLDTVV+S+QHAAD+DL+ L PDIR+ V+N ++ L D + ++LV Sbjct 184 IDYEGDKPARLDTVVLSSQHAADVDLDGMLAPDIRKHVVNPEVEALG---WDPAEPKLLV 240 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 241 NPTGRFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 300 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VAAGLA R+EVQVAYAIGKAAPVGLFVETFGTE DP KI+KAI EVFDLRP AIIRDL Sbjct 301 AVAAGLAGRIEVQVAYAIGKAAPVGLFVETFGTENVDPAKIQKAIEEVFDLRPAAIIRDL 360 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 LLRPIY PTAAYGHFGRTDVELPWE + D LK A+ Sbjct 361 KLLRPIYTPTAAYGHFGRTDVELPWEDTSRADALKSAV 398 >gi|333919532|ref|YP_004493113.1| S-adenosylmethionine synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333481753|gb|AEF40313.1| S-adenosylmethionine synthase [Amycolicicoccus subflavus DQS3-9A1] Length=404 Score = 624 bits (1608), Expect = 1e-176, Method: Compositional matrix adjust. Identities = 309/388 (80%), Positives = 339/388 (88%), Gaps = 4/388 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LD++L DPR+RVAVETLVTTGQVHV GEV+T+A Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDSILKEDPRARVAVETLVTTGQVHVAGEVSTTA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEG-AA 124 +ADI VR R+LEIGYDSS KGFDG +CGVN+ IGAQSP+IAQGV+ A+E+RVEG + Sbjct 65 -YADIPTIVRERVLEIGYDSSSKGFDGNSCGVNVAIGAQSPEIAQGVENAYESRVEGLSE 123 Query 125 DPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQV 184 D LD QGAGDQGLMFG+A TPELMPLPIALAHRLSRRLTE RK GVLPYLRPDGKTQV Sbjct 124 DDLDRQGAGDQGLMFGFACQDTPELMPLPIALAHRLSRRLTETRKTGVLPYLRPDGKTQV 183 Query 185 TIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVL 244 TI Y PVRLDTVV+STQHAADIDL+ L PDIR+ VL VL DL LD S V++L Sbjct 184 TIEYVGERPVRLDTVVVSTQHAADIDLDNLLAPDIRDHVLGAVLKDLDLPNLDTSEVKLL 243 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTG+FVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 244 VNPTGRFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 303 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA+R+EVQVAYAIGKAAPVGLFVE+FGTE DP+KI+ AI EVFDLRP AIIRD Sbjct 304 NAVAAGLADRLEVQVAYAIGKAAPVGLFVESFGTEKVDPLKIQSAIVEVFDLRPAAIIRD 363 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQ 392 L+LLRPIYA TAAYGHFGRTD++LPWEQ Sbjct 364 LDLLRPIYAQTAAYGHFGRTDIDLPWEQ 391 >gi|326382167|ref|ZP_08203859.1| S-adenosylmethionine synthetase [Gordonia neofelifaecis NRRL B-59395] gi|326198897|gb|EGD56079.1| S-adenosylmethionine synthetase [Gordonia neofelifaecis NRRL B-59395] Length=404 Score = 623 bits (1607), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 311/398 (79%), Positives = 337/398 (85%), Gaps = 4/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDA+LAADP ++VAVETLVTTGQVHV GEV T+A Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDAMLAADPHAKVAVETLVTTGQVHVAGEVNTTA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 + DI VR RILEIGYDSS KGFDGA+CGVN+ IGAQSP+IAQG+ +HE R D Sbjct 65 -YVDIPTIVRERILEIGYDSSTKGFDGASCGVNVAIGAQSPEIAQGLTASHEKRTGTHDD 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLTEVRKNG LPYLRPDGKTQVT Sbjct 124 EIDQQGAGDQGLMFGYATAETPELMPLPIALAHRLSRRLTEVRKNGTLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHET-LDASTVRVL 244 I Y + PVRLDTVV+STQHAADID++ L PDIR+ VL V +L LD S R+L Sbjct 184 IEYAGDTPVRLDTVVVSTQHAADIDIDGMLAPDIRKHVLEPVFAELDLPVKLDTSNPRLL 243 Query 245 VNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAK 304 VNPTG FVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAK Sbjct 244 VNPTGSFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAK 303 Query 305 NVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRD 364 N VAAGLA R+EVQVAYAIGKAAPVGLFVETFGTE DP I+KAI VFDLRPGAIIRD Sbjct 304 NAVAAGLASRIEVQVAYAIGKAAPVGLFVETFGTEKVDPGTIQKAISSVFDLRPGAIIRD 363 Query 365 LNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 L LL+PIYAPTAAYGHFGRTDV+LPWE+ D+VD L+ A Sbjct 364 LELLQPIYAPTAAYGHFGRTDVDLPWERTDRVDALREA 401 >gi|327309918|ref|YP_004336816.1| S-adenosylmethionine synthase [Pseudonocardia dioxanivorans CB1190] gi|326955253|gb|AEA28949.1| S-adenosylmethionine synthase [Pseudonocardia dioxanivorans CB1190] Length=400 Score = 622 bits (1605), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 312/401 (78%), Positives = 344/401 (86%), Gaps = 6/401 (1%) Query 2 SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTT 61 S RLFTSESVTEGHPDK+CDAISDSVLDALLA DPRSRVAVETLVTTGQVHV GEVTT Sbjct 3 SSNMRLFTSESVTEGHPDKMCDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVAGEVTT 62 Query 62 SAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVE 121 SA +ADI VR +ILEIGYDSS KGFDG +CGVN+ IGAQS DIAQGVDTA+E+RVE Sbjct 63 SA---YADIPTLVREKILEIGYDSSAKGFDGNSCGVNVAIGAQSADIAQGVDTAYESRVE 119 Query 122 GAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGK 181 + D + QGAGDQGLMFGYA TPEL+PLPIALAHRL+RRLTEVRK+GVLPYLRPDGK Sbjct 120 ASEDEIARQGAGDQGLMFGYANTDTPELLPLPIALAHRLARRLTEVRKSGVLPYLRPDGK 179 Query 182 TQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTV 241 TQVTI Y+ + VR+DTVV+S+QHAAD+DL+ L PDIRE V+ +LA LDA Sbjct 180 TQVTIEYDGDKAVRVDTVVVSSQHAADVDLDALLAPDIREHVVEP---ELARAGLDAEGA 236 Query 242 RVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRW 301 R+LVNPTG+FV+GGPMGDAGLTGRKIIVDTYGG+ARHGGGAFSGKDPSKVDRSAAYA+RW Sbjct 237 RLLVNPTGRFVVGGPMGDAGLTGRKIIVDTYGGFARHGGGAFSGKDPSKVDRSAAYALRW 296 Query 302 VAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAI 361 VAKN VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP +I+ AI EVFDLRP AI Sbjct 297 VAKNAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEHVDPTRIQSAITEVFDLRPAAI 356 Query 362 IRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 IRDL+LLRPIYA TAAYGHFGRTDVELPWE + D LK A Sbjct 357 IRDLDLLRPIYAQTAAYGHFGRTDVELPWESTSRADALKSA 397 >gi|343924558|ref|ZP_08764106.1| S-adenosylmethionine synthase [Gordonia alkanivorans NBRC 16433] gi|343765493|dbj|GAA11032.1| S-adenosylmethionine synthase [Gordonia alkanivorans NBRC 16433] Length=402 Score = 622 bits (1604), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 308/402 (77%), Positives = 344/402 (86%), Gaps = 3/402 (0%) Query 1 VSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 ++ RLFTSESVTEGHPDKICDAISDS+LDA+L DP +RVAVETLVTTGQVHV GEVT Sbjct 1 MTTSSRLFTSESVTEGHPDKICDAISDSILDAILTDDPNARVAVETLVTTGQVHVAGEVT 60 Query 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 T+A +ADI VR ++LEIGYDSS KGFDGA+CGVN+ IGAQSPDIA GV +HE+R Sbjct 61 TTA---YADIPKIVRDKVLEIGYDSSTKGFDGASCGVNVAIGAQSPDIAGGVFDSHESRS 117 Query 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 + D +D QGAGDQGLMFGYA N TPELMP+PIALAHRLSRRLTEVRKNG LPYLRPDG Sbjct 118 GISEDEIDKQGAGDQGLMFGYATNETPELMPVPIALAHRLSRRLTEVRKNGTLPYLRPDG 177 Query 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 KTQVTI Y+ + PVRLDTVV+STQHAADIDL+ L PDI++ V++ VL ++ +LD S Sbjct 178 KTQVTIEYDGDTPVRLDTVVLSTQHAADIDLDNLLAPDIKKHVVDAVLAEIGLPSLDTSD 237 Query 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 R+LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMR Sbjct 238 YRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMR 297 Query 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 WVAKN VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP IE+ I E FDLRP A Sbjct 298 WVAKNAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEHVDPAVIERVIKENFDLRPLA 357 Query 361 IIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 IIRDL+LLRPIY PTAAYGHFGRTDV+LPWE+ D+ D L+ A Sbjct 358 IIRDLDLLRPIYGPTAAYGHFGRTDVDLPWERTDRADKLRAA 399 >gi|256379242|ref|YP_003102902.1| S-adenosylmethionine synthetase [Actinosynnema mirum DSM 43827] gi|255923545|gb|ACU39056.1| S-adenosylmethionine synthetase [Actinosynnema mirum DSM 43827] Length=400 Score = 621 bits (1602), Expect = 6e-176, Method: Compositional matrix adjust. Identities = 311/390 (80%), Positives = 336/390 (87%), Gaps = 6/390 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LDALLA DP SRVAVETLVTTGQVHV GEVTT E Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDALLAKDPTSRVAVETLVTTGQVHVAGEVTT---E 63 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 A+ DI + VR +ILEIGYDSS KGFDG +CGVN+ IGAQSPDIAQGVDTA+E R A D Sbjct 64 AYVDIPSIVREKILEIGYDSSAKGFDGHSCGVNVAIGAQSPDIAQGVDTAYEQRTGDAGD 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 +D QGAGDQGLMFGYA TPELMPLPIALAHRLSRRLT VRK+G +PYLRPDGKTQVT Sbjct 124 DIDQQGAGDQGLMFGYACTDTPELMPLPIALAHRLSRRLTAVRKDGSVPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y + PVRLDTVV+STQHA IDLE+ L D+RE+V+ ++ L LD S VR+LV Sbjct 184 IEYAGDQPVRLDTVVVSTQHADGIDLEQLLGVDVRERVVAPEIEGLG---LDTSDVRLLV 240 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 241 NPTGRFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 300 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VAAGLA R+EVQVAYAIGKAAPVGLFVETFGTET DP KI++AI EVFDLRP AIIRDL Sbjct 301 AVAAGLATRIEVQVAYAIGKAAPVGLFVETFGTETVDPTKIQQAIAEVFDLRPAAIIRDL 360 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDK 395 NLLRPIYAPTAAYGHFGRTDVELPWE + Sbjct 361 NLLRPIYAPTAAYGHFGRTDVELPWEDTSR 390 >gi|331697242|ref|YP_004333481.1| S-adenosylmethionine synthase [Pseudonocardia dioxanivorans CB1190] gi|326951931|gb|AEA25628.1| S-adenosylmethionine synthase [Pseudonocardia dioxanivorans CB1190] Length=400 Score = 620 bits (1600), Expect = 9e-176, Method: Compositional matrix adjust. Identities = 310/397 (79%), Positives = 343/397 (87%), Gaps = 6/397 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDK+CDAISDSVLDALL DPRSRVAVETLVTTGQVHV GEVTTSA Sbjct 7 RLFTSESVTEGHPDKMCDAISDSVLDALLVQDPRSRVAVETLVTTGQVHVAGEVTTSA-- 64 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +ADI VR +ILEIGYDSS KGFDG +CGVN+ IGAQS DIAQGVDTA+E+RVE + D Sbjct 65 -YADIPTLVREKILEIGYDSSAKGFDGNSCGVNVAIGAQSADIAQGVDTAYESRVEASED 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 + QGAGDQGLMFGYA TPEL+PLPIALAHRL+RRLTEVRK+GVLPYLRPDGKTQVT Sbjct 124 EIARQGAGDQGLMFGYANTDTPELLPLPIALAHRLARRLTEVRKSGVLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y+ + VR+DTVV+S+QHAAD+DL+ L PDIRE V+ +LA LDA R+LV Sbjct 184 IEYDGDKAVRVDTVVVSSQHAADVDLDALLAPDIREHVVEP---ELARAGLDAEGARLLV 240 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG+ARHGGGAFSGKDPSKVDRSAAYA+RWVAKN Sbjct 241 NPTGRFVVGGPMGDAGLTGRKIIVDTYGGFARHGGGAFSGKDPSKVDRSAAYALRWVAKN 300 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VAAGLA+R+EVQVAYAIGKAAPVGLFVETFGTE DP++I+ AI EVFDLRP AIIRDL Sbjct 301 AVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEHVDPIRIQSAITEVFDLRPAAIIRDL 360 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 +LLRPIYA TAAYGHFGRTDVELPWE + D LK A Sbjct 361 DLLRPIYAQTAAYGHFGRTDVELPWESTARADALKSA 397 >gi|134098673|ref|YP_001104334.1| methionine adenosyltransferase 1 (AdoMet synthetase) [Saccharopolyspora erythraea NRRL 2338] gi|291003641|ref|ZP_06561614.1| methionine adenosyltransferase 1 (AdoMet synthetase) [Saccharopolyspora erythraea NRRL 2338] gi|133911296|emb|CAM01409.1| methionine adenosyltransferase 1 (AdoMet synthetase) [Saccharopolyspora erythraea NRRL 2338] Length=393 Score = 618 bits (1593), Expect = 6e-175, Method: Compositional matrix adjust. Identities = 309/396 (79%), Positives = 340/396 (86%), Gaps = 6/396 (1%) Query 7 LFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEA 66 +FTSESVTEGHPDKICDAISDS+LDALLA DPRSRVAVETLVTTGQVHV GEVTT EA Sbjct 1 MFTSESVTEGHPDKICDAISDSILDALLAQDPRSRVAVETLVTTGQVHVAGEVTT---EA 57 Query 67 FADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADP 126 +ADI VR +ILEIGYDSS KGFDG +CGVNI IGAQSPDIAQGVDT +E RVEG D Sbjct 58 YADIPTIVRDKILEIGYDSSAKGFDGNSCGVNIAIGAQSPDIAQGVDTGYETRVEGVIDE 117 Query 127 LDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTI 186 + QGAGDQGLMFGYA + TPE MPLPIALAHRLSRRLT+VRK+GVLPYLRPDGKTQVTI Sbjct 118 IAKQGAGDQGLMFGYACDDTPEYMPLPIALAHRLSRRLTKVRKDGVLPYLRPDGKTQVTI 177 Query 187 AYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVN 246 Y + VRLDTVV+S+QHAADIDL+K L D+RE+V+ +D L +D S VR+LVN Sbjct 178 EYAGDQAVRLDTVVVSSQHAADIDLDKMLGVDVREQVVGPEVDGL---DIDTSDVRLLVN 234 Query 247 PTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNV 306 PTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYA RWVAKN Sbjct 235 PTGRFVVGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYATRWVAKNA 294 Query 307 VAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLN 366 VAAGLA R+EVQVAYAIG AAPVGLFVETFGTE DP +I+ AI EVFDLRP AIIRDL+ Sbjct 295 VAAGLASRIEVQVAYAIGAAAPVGLFVETFGTENVDPARIQSAINEVFDLRPAAIIRDLD 354 Query 367 LLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 LLRPIYAPTAAYGHFGR D++LPWE+ D+ + LK A Sbjct 355 LLRPIYAPTAAYGHFGRPDLDLPWERTDRAEALKSA 390 >gi|302525875|ref|ZP_07278217.1| methionine adenosyltransferase [Streptomyces sp. AA4] gi|302434770|gb|EFL06586.1| methionine adenosyltransferase [Streptomyces sp. AA4] Length=400 Score = 616 bits (1588), Expect = 2e-174, Method: Compositional matrix adjust. Identities = 309/395 (79%), Positives = 335/395 (85%), Gaps = 6/395 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LD LL DPRSRVAVETL+TTGQVHV GEVTT E Sbjct 7 RLFTSESVTEGHPDKICDAISDSILDGLLTKDPRSRVAVETLITTGQVHVAGEVTT---E 63 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 A+ADI VR IL IGYDSS KGFDG +CGVN+ IG+QSPDIAQGVDTA+E+RVE D Sbjct 64 AYADIPTIVRDVILRIGYDSSAKGFDGNSCGVNVAIGSQSPDIAQGVDTAYESRVESDED 123 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 ++ QGAGDQGLMFGYA + TPELMPLPIALAHRLSRRLT VRK+GVLPYLRPDGKTQVT Sbjct 124 EINRQGAGDQGLMFGYACSDTPELMPLPIALAHRLSRRLTAVRKDGVLPYLRPDGKTQVT 183 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y PVRLDTVV+STQHA IDLE+ L D+R+ V+ L DL LD + R+LV Sbjct 184 IEYAGEQPVRLDTVVVSTQHADGIDLEQMLGVDVRKHVVEPELADLG---LDTDSTRLLV 240 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 241 NPTGRFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 300 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VVAAGLA RVEVQVAYAIGKAAPVGLFVETFGTET DP KI+ AI EVFDLRP AIIRDL Sbjct 301 VVAAGLAGRVEVQVAYAIGKAAPVGLFVETFGTETVDPSKIQSAISEVFDLRPAAIIRDL 360 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLK 400 +LLRPIYAPTAAYGHFGR D+ LPWE + D L+ Sbjct 361 DLLRPIYAPTAAYGHFGRPDLNLPWESTARADALR 395 >gi|257056683|ref|YP_003134515.1| methionine adenosyltransferase [Saccharomonospora viridis DSM 43017] gi|256586555|gb|ACU97688.1| methionine adenosyltransferase [Saccharomonospora viridis DSM 43017] Length=399 Score = 615 bits (1586), Expect = 4e-174, Method: Compositional matrix adjust. Identities = 303/390 (78%), Positives = 339/390 (87%), Gaps = 6/390 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISD++LDALLAADPRSRVAVETL+TTGQVH+ GEVTT E Sbjct 6 RLFTSESVTEGHPDKICDAISDTILDALLAADPRSRVAVETLITTGQVHIAGEVTT---E 62 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 A+ D+ VR R+LEIGYDSS KGFDGA+CGVN+ I +QSPDIAQGVD+A+EAR+E A D Sbjct 63 AYVDVPTLVRDRVLEIGYDSSAKGFDGASCGVNVAIDSQSPDIAQGVDSAYEARLENALD 122 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 LD QGAGDQGLMFGYA + TPELMPLPIALAHRLSRRLTEVRKNG +PYLRPDGKTQVT Sbjct 123 ELDRQGAGDQGLMFGYACSDTPELMPLPIALAHRLSRRLTEVRKNGTVPYLRPDGKTQVT 182 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y+ + PVRLDTVVIS+QHA IDLE L D+ + V+ ++ L LDAS + L+ Sbjct 183 IEYDGDRPVRLDTVVISSQHAEGIDLEGMLTHDLVKHVITPEIESLG---LDASEPKTLI 239 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 240 NPTGRFVVGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 299 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 +VAAGLA+R E+QVAYAIGKAAPVGLFVETFGTE DP KI+ AI EVFDLRP AIIRDL Sbjct 300 IVAAGLADRAEIQVAYAIGKAAPVGLFVETFGTEKVDPAKIQAAITEVFDLRPAAIIRDL 359 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDK 395 +LLRPIYAPTAAYGHFGR D++LPWE+ D+ Sbjct 360 DLLRPIYAPTAAYGHFGRIDIDLPWERTDR 389 >gi|298256329|gb|ADI71438.1| putative methionine adenosyltransferase [Amycolatopsis orientalis subsp. vinearia] Length=400 Score = 608 bits (1567), Expect = 6e-172, Method: Compositional matrix adjust. Identities = 301/391 (77%), Positives = 336/391 (86%), Gaps = 6/391 (1%) Query 2 SEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTT 61 + RLFTSESVTEGHPDKICDAISDS+LD LL+ DPRSRVAVETL+TTGQVHV GEVTT Sbjct 3 ASSSRLFTSESVTEGHPDKICDAISDSILDGLLSKDPRSRVAVETLITTGQVHVAGEVTT 62 Query 62 SAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVE 121 EA+ADI VR IL+IGYDSS KGFDG +CGVN+ IG+QSPDIAQGVDTA+E+RVE Sbjct 63 ---EAYADIPTIVRDVILKIGYDSSAKGFDGNSCGVNVAIGSQSPDIAQGVDTAYESRVE 119 Query 122 GAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGK 181 D ++ QGAGDQGLMFGYA + TPELMPLPIALAHRLS+RLT VRK+GVLPYLRPDGK Sbjct 120 SDEDEINRQGAGDQGLMFGYACSDTPELMPLPIALAHRLSKRLTAVRKDGVLPYLRPDGK 179 Query 182 TQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTV 241 TQVTI Y + PVRLDTVV+S+QHA IDLE+ L D++E V+ L+ L +D ++ Sbjct 180 TQVTIEYAGDQPVRLDTVVVSSQHADGIDLERMLSVDVKEHVVGPELEGLG---IDTASA 236 Query 242 RVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRW 301 R+LVNPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRW Sbjct 237 RLLVNPTGRFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRW 296 Query 302 VAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAI 361 VAKNVVAAGLA R EVQVAYAIGKAAPVGLFVETFGTET DP KI++AI EVFDLRP AI Sbjct 297 VAKNVVAAGLASRTEVQVAYAIGKAAPVGLFVETFGTETVDPSKIQQAITEVFDLRPAAI 356 Query 362 IRDLNLLRPIYAPTAAYGHFGRTDVELPWEQ 392 IRDL+LLRPIYAPTAAYGHFGR ++ LPWE Sbjct 357 IRDLDLLRPIYAPTAAYGHFGRPELGLPWES 387 >gi|254383678|ref|ZP_04999027.1| SAM synthetase [Streptomyces sp. Mg1] gi|194342572|gb|EDX23538.1| SAM synthetase [Streptomyces sp. Mg1] Length=402 Score = 606 bits (1562), Expect = 2e-171, Method: Compositional matrix adjust. Identities = 304/399 (77%), Positives = 338/399 (85%), Gaps = 5/399 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKI D ISD++LDALLA DP SRVAVETL+TTGQVH+ GEVTT+A Sbjct 4 RLFTSESVTEGHPDKIADQISDTILDALLAQDPTSRVAVETLITTGQVHIAGEVTTTA-- 61 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +A I VR +ILEIGYDSS KGFDGA+CGV+I IGAQSPDIAQGVDTA+E RVEG D Sbjct 62 -YAPIAQLVRDKILEIGYDSSAKGFDGASCGVSISIGAQSPDIAQGVDTAYETRVEGDED 120 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 LD QGAGDQGLMFGYA + TPELMPLPI LAHRLSRRL+EVRK+G +PYLRPDGKTQVT Sbjct 121 ELDKQGAGDQGLMFGYATDETPELMPLPIHLAHRLSRRLSEVRKSGAVPYLRPDGKTQVT 180 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHE--TLDASTVRV 243 IAYE + VRLDTVV+S+QHAAD+DLEK L PD+RE V+ VL +LA + LD R+ Sbjct 181 IAYEGDKAVRLDTVVVSSQHAADVDLEKLLTPDVRELVVEHVLKELAKDGIKLDTEGYRL 240 Query 244 LVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVA 303 LVNPTG+F +GGPMGDAGLTGRKII+DTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVA Sbjct 241 LVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVA 300 Query 304 KNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIR 363 KNVVAAGLA R EVQVAYAIGKA PVGLFVETFGT + KIE AIG+VFDLRP AIIR Sbjct 301 KNVVAAGLASRCEVQVAYAIGKAEPVGLFVETFGTAKVEVQKIEDAIGQVFDLRPAAIIR 360 Query 364 DLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRA 402 DL+LLRPIYA TAAYGHFGR + WE+ D+VD L++A Sbjct 361 DLDLLRPIYAQTAAYGHFGRELPDFTWERTDRVDALRQA 399 >gi|258654281|ref|YP_003203437.1| S-adenosylmethionine synthetase [Nakamurella multipartita DSM 44233] gi|258557506|gb|ACV80448.1| S-adenosylmethionine synthetase [Nakamurella multipartita DSM 44233] Length=397 Score = 605 bits (1561), Expect = 3e-171, Method: Compositional matrix adjust. Identities = 304/398 (77%), Positives = 337/398 (85%), Gaps = 6/398 (1%) Query 6 RLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKE 65 RLFTSESVTEGHPDKICDAISDS+LD LL DP SRVAVET+VTTGQVHV GEVTTSA Sbjct 4 RLFTSESVTEGHPDKICDAISDSILDELLRQDPSSRVAVETMVTTGQVHVAGEVTTSA-- 61 Query 66 AFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAAD 125 +ADI VR +L IGYDSS KGFDGA+CGVN+ IGAQSPDIAQGVDTA+E+RV+G D Sbjct 62 -YADIPAIVRDTVLGIGYDSSAKGFDGASCGVNVAIGAQSPDIAQGVDTAYESRVDGTVD 120 Query 126 PLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVT 185 L+ QGAGDQGLMFGYA TPELMPLPIALAHRLSR LT VRK+G +PYLRPDGKTQVT Sbjct 121 ELEQQGAGDQGLMFGYACTDTPELMPLPIALAHRLSRSLTGVRKSGAVPYLRPDGKTQVT 180 Query 186 IAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLV 245 I Y + VRLDTVV+STQHA +IDLE+ L D+RE+V+ +LA +D R+LV Sbjct 181 IEYVGDKAVRLDTVVVSTQHAENIDLEQLLAVDVREQVVEP---ELAALDIDTQGYRLLV 237 Query 246 NPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 305 NPTG+FV+GGPMGDAGLTGRKIIVDTYGG ARHGGGAFSGKDPSKVDRSAAYAMRWVAKN Sbjct 238 NPTGRFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKN 297 Query 306 VVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDL 365 VVAAGLA+R+EVQVAYAIGKA+PVGLFVETFGTE DP KI +AI +VFDLRP AIIRDL Sbjct 298 VVAAGLADRIEVQVAYAIGKASPVGLFVETFGTEQVDPDKIAEAIKQVFDLRPAAIIRDL 357 Query 366 NLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI 403 +L RPIYA TAAYGHFGRTDV+LPWE D+ DLK A+ Sbjct 358 DLKRPIYAQTAAYGHFGRTDVDLPWESTDRAADLKSAL 395 Lambda K H 0.316 0.136 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 797946486552 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40