BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1415 Length=425 Score E Sequences producing significant alignments: (Bits) Value gi|15608553|ref|NP_215931.1| bifunctional 3,4-dihydroxy-2-butano... 854 0.0 gi|289447011|ref|ZP_06436755.1| riboflavin biosynthesis protein ... 853 0.0 gi|340626429|ref|YP_004744881.1| putative riboflavin biosynthesi... 851 0.0 gi|308231835|ref|ZP_07413935.2| riboflavin biosynthesis protein ... 847 0.0 gi|254775811|ref|ZP_05217327.1| bifunctional 3,4-dihydroxy-2-but... 840 0.0 gi|41407238|ref|NP_960074.1| bifunctional 3,4-dihydroxy-2-butano... 840 0.0 gi|118464982|ref|YP_882547.1| bifunctional 3,4-dihydroxy-2-butan... 839 0.0 gi|296170720|ref|ZP_06852294.1| 3,4-dihydroxy-2-butanone 4-phosp... 838 0.0 gi|183982235|ref|YP_001850526.1| riboflavin biosynthesis protein... 835 0.0 gi|254822409|ref|ZP_05227410.1| bifunctional 3,4-dihydroxy-2-but... 829 0.0 gi|342858708|ref|ZP_08715363.1| bifunctional 3,4-dihydroxy-2-but... 828 0.0 gi|2183211|gb|AAB60877.1| RibA [Mycobacterium tuberculosis H37Rv] 828 0.0 gi|118617424|ref|YP_905756.1| bifunctional 3,4-dihydroxy-2-butan... 825 0.0 gi|240172788|ref|ZP_04751447.1| bifunctional 3,4-dihydroxy-2-but... 820 0.0 gi|15827210|ref|NP_301473.1| bifunctional 3,4-dihydroxy-2-butano... 810 0.0 gi|333990925|ref|YP_004523539.1| riboflavin biosynthesis protein... 791 0.0 gi|120403678|ref|YP_953507.1| bifunctional 3,4-dihydroxy-2-butan... 789 0.0 gi|145224301|ref|YP_001134979.1| bifunctional 3,4-dihydroxy-2-bu... 789 0.0 gi|118470936|ref|YP_887388.1| bifunctional 3,4-dihydroxy-2-butan... 783 0.0 gi|108799357|ref|YP_639554.1| bifunctional 3,4-dihydroxy-2-butan... 781 0.0 gi|169629880|ref|YP_001703529.1| bifunctional 3,4-dihydroxy-2-bu... 750 0.0 gi|226306509|ref|YP_002766469.1| riboflavin biosynthesis bifunct... 734 0.0 gi|111024120|ref|YP_707092.1| bifunctional 3,4-dihydroxy-2-butan... 733 0.0 gi|226366360|ref|YP_002784143.1| bifunctional 3,4-dihydroxy-2-bu... 731 0.0 gi|312139595|ref|YP_004006931.1| 3,4-dihydroxy-2-butanone 4-phos... 718 0.0 gi|325676730|ref|ZP_08156404.1| 3,4-dihydroxy-2-butanone 4-phosp... 716 0.0 gi|262202282|ref|YP_003273490.1| GTP cyclohydrolase II [Gordonia... 713 0.0 gi|343924573|ref|ZP_08764121.1| riboflavin biosynthesis protein ... 711 0.0 gi|296140260|ref|YP_003647503.1| GTP cyclohydrolase II [Tsukamur... 697 0.0 gi|326382174|ref|ZP_08203866.1| bifunctional 3,4-dihydroxy-2-but... 685 0.0 gi|333919549|ref|YP_004493130.1| GTP cyclohydrolase-2 [Amycolici... 681 0.0 gi|54025570|ref|YP_119812.1| bifunctional 3,4-dihydroxy-2-butano... 672 0.0 gi|289442860|ref|ZP_06432604.1| riboflavin biosynthesis protein ... 664 0.0 gi|317508956|ref|ZP_07966589.1| 3,4-dihydroxy-2-butanone 4-phosp... 637 1e-180 gi|296395031|ref|YP_003659915.1| GTP cyclohydrolase II [Segnilip... 632 4e-179 gi|257055603|ref|YP_003133435.1| bifunctional 3,4-dihydroxy-2-bu... 620 1e-175 gi|302525889|ref|ZP_07278231.1| 3,4-dihydroxy-2-butanone 4-phosp... 612 4e-173 gi|291003620|ref|ZP_06561593.1| bifunctional 3,4-dihydroxy-2-but... 610 2e-172 gi|134098693|ref|YP_001104354.1| bifunctional 3,4-dihydroxy-2-bu... 609 2e-172 gi|300784679|ref|YP_003764970.1| GTP cyclohydrolase II/3,4-dihyd... 598 7e-169 gi|256379225|ref|YP_003102885.1| 3,4-dihydroxy-2-butanone 4-phos... 595 4e-168 gi|331697231|ref|YP_004333470.1| 3,4-dihydroxy-2-butanone 4-phos... 593 1e-167 gi|298524920|ref|ZP_07012329.1| bifunctional 3,4-dihydroxy-2-but... 593 2e-167 gi|336179148|ref|YP_004584523.1| GTP cyclohydrolase-2 [Frankia s... 586 2e-165 gi|324999322|ref|ZP_08120434.1| bifunctional 3,4-dihydroxy-2-but... 583 1e-164 gi|158313560|ref|YP_001506068.1| bifunctional 3,4-dihydroxy-2-bu... 577 2e-162 gi|227488845|ref|ZP_03919161.1| 3,4-dihydroxy-2-butanone-4-phosp... 576 3e-162 gi|302866842|ref|YP_003835479.1| 3,4-dihydroxy-2-butanone 4-phos... 573 2e-161 gi|213965612|ref|ZP_03393806.1| riboflavin biosynthesis protein ... 573 3e-161 gi|312195563|ref|YP_004015624.1| 3,4-dihydroxy-2-butanone 4-phos... 571 9e-161 >gi|15608553|ref|NP_215931.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium tuberculosis H37Rv] gi|15840872|ref|NP_335909.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium tuberculosis CDC1551] gi|31792609|ref|NP_855102.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium bovis AF2122/97] 65 more sequence titles Length=425 Score = 854 bits (2207), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|289447011|ref|ZP_06436755.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis CPHL_A] gi|289419969|gb|EFD17170.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis CPHL_A] Length=425 Score = 853 bits (2204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/425 (99%), Positives = 424/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAE RIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAETRIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|340626429|ref|YP_004744881.1| putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium canettii CIPT 140010059] gi|340004619|emb|CCC43763.1| putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) [Mycobacterium canettii CIPT 140010059] Length=425 Score = 851 bits (2198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/425 (99%), Positives = 423/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHES HLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESAHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|308231835|ref|ZP_07413935.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu001] gi|308375456|ref|ZP_07443983.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu007] gi|308377722|ref|ZP_07480174.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu009] gi|308380069|ref|ZP_07488586.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu011] gi|308215908|gb|EFO75307.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu001] gi|308346238|gb|EFP35089.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu007] gi|308354831|gb|EFP43682.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu009] gi|308362717|gb|EFP51568.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis SUMu011] Length=422 Score = 847 bits (2189), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/422 (99%), Positives = 422/422 (100%), Gaps = 0/422 (0%) Query 4 LDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 63 +DSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG Sbjct 1 MDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 60 Query 64 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 123 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT Sbjct 61 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 120 Query 124 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 183 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV Sbjct 121 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 180 Query 184 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 243 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR Sbjct 181 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 240 Query 244 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 303 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE Sbjct 241 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 300 Query 304 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 363 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP Sbjct 301 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 360 Query 364 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGG 423 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGG Sbjct 361 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGG 420 Query 424 AL 425 AL Sbjct 421 AL 422 >gi|254775811|ref|ZP_05217327.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium avium subsp. avium ATCC 25291] gi|336461615|gb|EGO40480.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=425 Score = 840 bits (2171), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/425 (97%), Positives = 422/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNG+GTGISASDRATTMRLLADPTS+A+ Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LA+ITIADLIEWRRKHEKHIER+AEARIPTRHGEFRAIGYTSIYE+VEHVA Sbjct 181 LRVFADEHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|41407238|ref|NP_960074.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium avium subsp. paratuberculosis K-10] gi|81571405|sp|Q741F1.1|RIBBA_MYCPA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|41395589|gb|AAS03457.1| RibA2 [Mycobacterium avium subsp. paratuberculosis K-10] Length=425 Score = 840 bits (2169), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/425 (97%), Positives = 421/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNG+GTGISASDRATTMRLLADPTS+A+ Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LA+ITIADLIEWRRKHEKHIER+AEARIPTRHGEFRAIGYTSIYE+VEHVA Sbjct 181 LRVFADEHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVR NAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRTNAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|118464982|ref|YP_882547.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium avium 104] gi|166977457|sp|A0QI09.1|RIBBA_MYCA1 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|118166269|gb|ABK67166.1| riboflavin biosynthesis protein ribAB [Mycobacterium avium 104] Length=425 Score = 839 bits (2168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/425 (97%), Positives = 421/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNG+GTGISASDRATTMRLLADPTS+A+ Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LA+ITIADLIEWRRKHEKHIER+AEARIPTRHGEFRAIGYTSIYE+VEHVA Sbjct 181 LRVFADEHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLG PADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGFPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|296170720|ref|ZP_06852294.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894624|gb|EFG74359.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Mycobacterium parascrofulaceum ATCC BAA-614] Length=425 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/425 (97%), Positives = 420/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNG+GTGISASDRATTMRLL+DP SVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLSDPASVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LALITIADLIEWRRKHEKHIER+AEARIPTRHGEFRAIGY SIYEDVEHVA Sbjct 181 LRVFADEHDLALITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYASIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|183982235|ref|YP_001850526.1| riboflavin biosynthesis protein RibA2 [Mycobacterium marinum M] gi|226739258|sp|B2HP67.1|RIBBA_MYCMM RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|183175561|gb|ACC40671.1| riboflavin biosynthesis protein RibA2 [Mycobacterium marinum M] Length=425 Score = 835 bits (2157), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/425 (97%), Positives = 420/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADI AGKAVIVIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIGAGKAVIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA+CDRLGLLPMYAVNQDKHGTAYTVTVDA+NG+GTGISASDRATTMRLLADP SVA+ Sbjct 61 LDGAVCDRLGLLPMYAVNQDKHGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLLHKLQAYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLTGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|254822409|ref|ZP_05227410.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium intracellulare ATCC 13950] Length=425 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/425 (96%), Positives = 419/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDA++G+GTGISASDRATTMRLLA+P SVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDAKDGVGTGISASDRATTMRLLANPISVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LA+ITIADLIEWRRKHEKHI R+AEARIPTRHGEFRAIGY SIYE+VEHVA Sbjct 181 LRVFADEHDLAMITIADLIEWRRKHEKHIARIAEARIPTRHGEFRAIGYASIYEEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGP++DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGEIAGPDSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|342858708|ref|ZP_08715363.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium colombiense CECT 3035] gi|342134412|gb|EGT87592.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium colombiense CECT 3035] Length=425 Score = 828 bits (2140), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/425 (96%), Positives = 417/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG ICDRLGLLPMYAVNQDKHGTAYTVTVDAR G+GTGISASDRATTMRLLADPTS AD Sbjct 61 LDGEICDRLGLLPMYAVNQDKHGTAYTVTVDARRGVGTGISASDRATTMRLLADPTSAAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAGAICEIVSQKDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LA+ITIADLIEWRRKHEKHI R+AEARIPTRHGEFRAIGY SIYE+VEHVA Sbjct 181 LRVFADEHDLAMITIADLIEWRRKHEKHIARIAEARIPTRHGEFRAIGYASIYEEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG+IAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGDIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDK+GHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|2183211|gb|AAB60877.1| RibA [Mycobacterium tuberculosis H37Rv] Length=425 Score = 828 bits (2139), Expect = 0.0, Method: Compositional matrix adjust. Identities = 413/425 (98%), Positives = 416/425 (98%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFA EKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAPEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAI DRLGL PMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATT+ LLADPTSV+D Sbjct 61 LDGAISDRLGLFPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTIGLLADPTSVSD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFT PGHVVPLRAKDGGVLRRPGHTE VDL+RMAGLQPAGAICEIVSQKDEGSMAHTDE Sbjct 121 DFTPPGHVVPLRAKDGGVLRRPGHTETPVDLSRMAGLQPAGAICEIVSQKDEGSMAHTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHII RVPLPVRANAENIR LMTKRDKLGHDLAGLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIGRVPLPVRANAENIRCLMTKRDKLGHDLAGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|118617424|ref|YP_905756.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium ulcerans Agy99] gi|166977460|sp|A0PPL6.1|RIBBA_MYCUA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|118569534|gb|ABL04285.1| riboflavin biosynthesis protein RibA2 [Mycobacterium ulcerans Agy99] Length=425 Score = 825 bits (2130), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/425 (96%), Positives = 417/425 (99%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADI AGKAVIVIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIGAGKAVIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA+CDRLGLLPMYAVNQDKHGTAYTVTVDA+NG+GTGISASDRATTMRLLADP SVA+ Sbjct 61 LDGAVCDRLGLLPMYAVNQDKHGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVS+KDEGSMA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSRKDEGSMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTR GEFRAIGYTSIYE+VEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRRGEFRAIGYTSIYENVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPN+DGDDVLVRVHSECLTGDVFGSRRCDCG QLDAA+AMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGSQLDAAMAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKLQ YQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLLHKLQTYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GLDDFHESVHLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLTGLDDFHESVHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|240172788|ref|ZP_04751447.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium kansasii ATCC 12478] Length=428 Score = 820 bits (2117), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/428 (95%), Positives = 418/428 (98%), Gaps = 3/428 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKA+IVIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAIIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG+ICDRLGLLPM+AVNQDKHGTAYTVTVDAR GIGTGISASDRATTMRLLADP S AD Sbjct 61 LDGSICDRLGLLPMFAVNQDKHGTAYTVTVDARQGIGTGISASDRATTMRLLADPASNAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAGAICEIVSQKDEG+MA TDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGAMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKH+ER+AEARIPTRHGEFRAIGY+SIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHVERIAEARIPTRHGEFRAIGYSSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLD---DFHESVHL 417 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GLD +F ESV L Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLVGLDEFGNFQESVPL 420 Query 418 PGEFGGAL 425 PGEFGGAL Sbjct 421 PGEFGGAL 428 >gi|15827210|ref|NP_301473.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium leprae TN] gi|221229688|ref|YP_002503104.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium leprae Br4923] gi|13092758|emb|CAC30067.1| putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase [Mycobacterium leprae] gi|219932795|emb|CAR70652.1| putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase [Mycobacterium leprae Br4923] Length=435 Score = 810 bits (2091), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/425 (94%), Positives = 411/425 (97%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAV+VIDDEDRENEGDLIFAAEKAT EMVAFMVRYTSGYLC P Sbjct 11 MTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATLEMVAFMVRYTSGYLCAP 70 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPM+AVNQDKHGTAYTVTVDARNG+GTGISASDRATTMRLLADP SVAD Sbjct 71 LDGAICDRLGLLPMFAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPASVAD 130 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAGAICEIVSQKDEGSMA TDE Sbjct 131 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGSMAQTDE 190 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LALITIADLI WRRKHEKHIERVAEARIPTRHGEFRAIGYTSIY+DV+HVA Sbjct 191 LRVFADEHDLALITIADLIAWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYDDVKHVA 250 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAG + DGDD+LVRVHSECLTGDVFGSRRCDCG QLDAA+AMVAREGRGVVLYMR Sbjct 251 LVRGEIAGSSGDGDDILVRVHSECLTGDVFGSRRCDCGTQLDAAMAMVAREGRGVVLYMR 310 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAGADTVDAN+KLG P+DARDYGIGAQILVDLGVRSMRLLT Sbjct 311 GHEGRGIGLMHKLQAYQLQDAGADTVDANIKLGFPSDARDYGIGAQILVDLGVRSMRLLT 370 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGL IIERVPLPVRANA+NIRYLMTKRDK+GHDL GLDDFHES + PGE Sbjct 371 NNPAKRVGLDGYGLQIIERVPLPVRANADNIRYLMTKRDKMGHDLGGLDDFHESNYFPGE 430 Query 421 FGGAL 425 FGGAL Sbjct 431 FGGAL 435 >gi|333990925|ref|YP_004523539.1| riboflavin biosynthesis protein RibA2 [Mycobacterium sp. JDM601] gi|333486893|gb|AEF36285.1| riboflavin biosynthesis protein RibA2 [Mycobacterium sp. JDM601] Length=425 Score = 791 bits (2043), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/425 (93%), Positives = 415/425 (98%), Gaps = 0/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MT+LD+VERAVADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTKLDTVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYA+NQDKHGTAYTVTVDA+N +GTGISASDRATTMRLLADP + AD Sbjct 61 LDGAICDRLGLLPMYALNQDKHGTAYTVTVDAKNNVGTGISASDRATTMRLLADPAAAAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 +FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEG+MA TDE Sbjct 121 EFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGAMAKTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLA+I+IAD+IEWRRKHEKHIERVAEARIPTRHGEFRA+GYTSIYEDVEHVA Sbjct 181 LRVFADEHGLAMISIADMIEWRRKHEKHIERVAEARIPTRHGEFRAVGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGP+ DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVA EGRGVVLYMR Sbjct 241 LVRGEIAGPHNDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAHEGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLLHKLQAYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GL++F +S HLPGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLTGLEEFDDSSHLPGE 420 Query 421 FGGAL 425 FGGAL Sbjct 421 FGGAL 425 >gi|120403678|ref|YP_953507.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium vanbaalenii PYR-1] gi|166977461|sp|A1T8K1.1|RIBBA_MYCVP RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|119956496|gb|ABM13501.1| GTP cyclohydrolase II [Mycobacterium vanbaalenii PYR-1] Length=423 Score = 789 bits (2038), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/425 (92%), Positives = 409/425 (97%), Gaps = 2/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L G ICDRLGLLPMYAVNQDKHGTAYTVTVDA+ G+GTGISA DRATTMRLLADP +VAD Sbjct 61 LAGDICDRLGLLPMYAVNQDKHGTAYTVTVDAKKGVGTGISAMDRATTMRLLADPDAVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFT+PGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAGAICEIVSQKDEG+MA TDE Sbjct 121 DFTKPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGAMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LR+FADEH LALI+IADLIEWRRKHEKHI RVAEARIPTRHGEFRA+GYTSIYEDVEHVA Sbjct 181 LRIFADEHDLALISIADLIEWRRKHEKHIARVAEARIPTRHGEFRAVGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV+GEI+GP++DG DVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVKGEISGPHSDGHDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYG GAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGDDTVDANLKLGLPADARDYGTGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GL+DF E+V PGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLVGLEDFDEAV--PGE 418 Query 421 FGGAL 425 GGA+ Sbjct 419 LGGAV 423 >gi|145224301|ref|YP_001134979.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium gilvum PYR-GCK] gi|315444634|ref|YP_004077513.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium sp. Spyr1] gi|189040098|sp|A4TC13.1|RIBBA_MYCGI RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|145216787|gb|ABP46191.1| GTP cyclohydrolase II [Mycobacterium gilvum PYR-GCK] gi|315262937|gb|ADT99678.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium sp. Spyr1] Length=423 Score = 789 bits (2038), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/425 (92%), Positives = 408/425 (96%), Gaps = 2/425 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L G ICDRLGLLPMYAVNQDKHGTAYTVTVDA+ G+GTGISASDRATTMRLLADP SVAD Sbjct 61 LAGEICDRLGLLPMYAVNQDKHGTAYTVTVDAKVGVGTGISASDRATTMRLLADPDSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFT+PGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQ AG ICEIVSQKDEG+MA TDE Sbjct 121 DFTKPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQAAGTICEIVSQKDEGAMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LR+FADEH LALI+IADLIEWRRKHEKHI RVAEARIPTRHGEFRA+GYTSIYEDVEHVA Sbjct 181 LRIFADEHDLALISIADLIEWRRKHEKHIARVAEARIPTRHGEFRAVGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV+G+IAGP+ DG DVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRG+VLYMR Sbjct 241 LVKGDIAGPHGDGHDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYG GAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGDDTVDANLKLGLPADARDYGTGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGE 420 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRD++GHDL GLDDF E+V PGE Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDRMGHDLVGLDDFDEAV--PGE 418 Query 421 FGGAL 425 FGGA+ Sbjct 419 FGGAV 423 >gi|118470936|ref|YP_887388.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium smegmatis str. MC2 155] gi|118172223|gb|ABK73119.1| riboflavin biosynthesis protein ribAB [Mycobacterium smegmatis str. MC2 155] Length=439 Score = 783 bits (2021), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/417 (92%), Positives = 402/417 (97%), Gaps = 0/417 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERA+ADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAIADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG ICDRLGLLPMYAVNQDKHGTAYTVTVDA+ +GTGISASDRATTMR LA+P SVAD Sbjct 61 LDGEICDRLGLLPMYAVNQDKHGTAYTVTVDAKKDVGTGISASDRATTMRALANPGSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFT+PGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAGAICEIVSQKDEG MA TDE Sbjct 121 DFTKPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGDMARTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLIEWRRKHEKHIER+AEARIPTRHGEFRA+GY SIYEDVEHVA Sbjct 181 LRVFADDHDLALISIADLIEWRRKHEKHIERIAEARIPTRHGEFRAVGYKSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEI+GP +DGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRGVVLYMR Sbjct 241 LVRGEISGPGSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLG+RSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGIRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHL 417 NNPAKRVGLDGYGLHIIERVPLPVRAN ENIRYLMTKRD++GHDL GLDD+ E+V + Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANKENIRYLMTKRDRMGHDLVGLDDYDEAVSM 417 >gi|108799357|ref|YP_639554.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium sp. MCS] gi|119868473|ref|YP_938425.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium sp. KMS] gi|126435015|ref|YP_001070706.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium sp. JLS] gi|108769776|gb|ABG08498.1| GTP cyclohydrolase II [Mycobacterium sp. MCS] gi|119694562|gb|ABL91635.1| GTP cyclohydrolase II [Mycobacterium sp. KMS] gi|126234815|gb|ABN98215.1| GTP cyclohydrolase II [Mycobacterium sp. JLS] Length=439 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/429 (90%), Positives = 409/429 (96%), Gaps = 9/429 (2%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERA+ADIAAGKAV+VIDDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAIADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDA++G+GTGISASDRATTMRLLADPTS AD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDAKHGVGTGISASDRATTMRLLADPTSNAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 +FT+PGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGLQPAG ICEIVSQKDEG+MA TDE Sbjct 121 EFTKPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGTICEIVSQKDEGAMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LR+FADEH LALI+IADLIEWRRKHE+HIER+AEARIPTRHGEFRA+GYTSIY+DVEHVA Sbjct 181 LRIFADEHDLALISIADLIEWRRKHERHIERIAEARIPTRHGEFRAVGYTSIYDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG++AGP+ DG DVLVRVHSECLTGDVFGSRRCDCGPQLDAA+AMVAREGRG+VLYMR Sbjct 241 LVRGDVAGPHGDGHDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGL---------DDF 411 NNPAKRVGLDGYGLH+IERVPLPVRANAENIRYLMTKRD++GHDL GL DD+ Sbjct 361 NNPAKRVGLDGYGLHVIERVPLPVRANAENIRYLMTKRDRMGHDLTGLDEYDEANSMDDY 420 Query 412 HESVHLPGE 420 E V+L GE Sbjct 421 DEGVYLLGE 429 >gi|169629880|ref|YP_001703529.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Mycobacterium abscessus ATCC 19977] gi|226739257|sp|B1MCA4.1|RIBBA_MYCA9 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|169241847|emb|CAM62875.1| Putative riboflavin biosynthesis protein RibA2 [Mycobacterium abscessus] Length=417 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/414 (88%), Positives = 394/414 (96%), Gaps = 0/414 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDS+ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRLDSIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L G CDRLGLLP YAVNQDKHGTAYTVTVDA+NGIGTGISASDRA TMRLLAD S AD Sbjct 61 LAGEDCDRLGLLPQYAVNQDKHGTAYTVTVDAKNGIGTGISASDRAATMRLLADAASTAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFT+PGHVVPLRAKDGGVLRRPGHTEA+VDLA++AGL+PA ICEIVSQKDEG+MA T+E Sbjct 121 DFTKPGHVVPLRAKDGGVLRRPGHTEASVDLAKLAGLRPAAVICEIVSQKDEGAMAQTEE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LAL++IADLIEWRRKHEKH++R+AEARIPT+HGEFRA+GYTSIY+DVEHVA Sbjct 181 LRVFADEHNLALVSIADLIEWRRKHEKHVQRIAEARIPTQHGEFRAVGYTSIYDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV G+I+GP+ DG+DVLVRVHSECLTGDVFGSRRCDCGPQLDAA+ MVA+EGRG+VLYMR Sbjct 241 LVLGDISGPDGDGNDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMEMVAKEGRGIVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG DTVDANLKLGLPADARDYG+GAQILVDLGV+SMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGLGAQILVDLGVKSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHES 414 NNPAKRVGLDGYGLHIIERVPLPVRAN+ENIRYL TKRD++GHDLA LDD E+ Sbjct 361 NNPAKRVGLDGYGLHIIERVPLPVRANSENIRYLRTKRDRMGHDLADLDDHPEA 414 >gi|226306509|ref|YP_002766469.1| riboflavin biosynthesis bifunctional protein RibA [Rhodococcus erythropolis PR4] gi|229493497|ref|ZP_04387282.1| riboflavin biosynthesis protein ribBA [Rhodococcus erythropolis SK121] gi|259585625|sp|C0ZZE5.1|RIBBA_RHOE4 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|226185626|dbj|BAH33730.1| riboflavin biosynthesis bifunctional protein RibA [Rhodococcus erythropolis PR4] gi|229319458|gb|EEN85294.1| riboflavin biosynthesis protein ribBA [Rhodococcus erythropolis SK121] Length=424 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/421 (86%), Positives = 390/421 (93%), Gaps = 2/421 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR DS+ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRFDSIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG CDRLGL PMYA NQDKHGTAYTVTVDAR GIGTGISASDRA TMRLLA+P S A+ Sbjct 61 LDGDDCDRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLANPESGAN 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLARMA L+PAG ICEIVSQKDEG+MA TDE Sbjct 121 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGAMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEH LALI+IADLI WRRKHEKH+ R+AEARIPTRHGEF A+GYTSIY++VEHVA Sbjct 181 LRVFADEHNLALISIADLIAWRRKHEKHVLRIAEARIPTRHGEFTAVGYTSIYDEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG+IAGP+ DG DVLVRVHSECLTGDVFGS RCDCGPQLDAAL MVA+EGRGVVLYMR Sbjct 241 LVRGDIAGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL+LGLPADARDYGIGAQILVDLG+ SMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF--HESVHLP 418 NNPAKRVGLDGYGL I +RVP+P+RANAEN+ YL TKRD++GHDL GLD++ +++ P Sbjct 361 NNPAKRVGLDGYGLQITDRVPMPLRANAENLTYLRTKRDRMGHDLIGLDEYEANQNTAQP 420 Query 419 G 419 G Sbjct 421 G 421 >gi|111024120|ref|YP_707092.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Rhodococcus jostii RHA1] gi|123144023|sp|Q0S0K2.1|RIBBA_RHOSR RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|110823650|gb|ABG98934.1| GTP cyclohydrolase II [Rhodococcus jostii RHA1] Length=417 Score = 733 bits (1892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/411 (88%), Positives = 382/411 (93%), Gaps = 0/411 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR DS+ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRFDSIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA CDRLGL PMYA NQDKHGTAYTVTVDAR GIGTGISASDRA TMRLLADP+S A Sbjct 61 LDGADCDRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQ 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLARMA L+PAG ICEIVSQKDEG MA TDE Sbjct 121 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLI WRRKHEKH+ERVA ARIPTRHGEF A+GY SIY+DVEHVA Sbjct 181 LRVFADDHNLALISIADLIAWRRKHEKHVERVASARIPTRHGEFTAVGYRSIYDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG++ GP+ DG DVLVRVHSECLTGDVFGS RCDCGPQLDAAL MVA+EGRGVVLYMR Sbjct 241 LVRGDLPGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL+LGLPADARDYGIGAQILVDLG+ SMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF 411 NNPAKRVGLDGYGL I ERV +P+RANAEN+ YL TKRD++GHDL GLDDF Sbjct 361 NNPAKRVGLDGYGLQITERVSMPLRANAENLTYLRTKRDRMGHDLIGLDDF 411 >gi|226366360|ref|YP_002784143.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Rhodococcus opacus B4] gi|226244850|dbj|BAH55198.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Rhodococcus opacus B4] Length=417 Score = 731 bits (1886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/411 (87%), Positives = 382/411 (93%), Gaps = 0/411 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR D++ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRFDTIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA CDRLGL PMYA NQDKHGTAYTVTVDAR GIGTGISASDRA TMRLLADP+S A Sbjct 61 LDGADCDRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQ 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLARMA L+PAG ICEIVSQKDEG MA TDE Sbjct 121 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLI WRRKHEKH+ERVA ARIPTRHGEF A+GY SIY+DVEHVA Sbjct 181 LRVFADDHDLALISIADLIAWRRKHEKHVERVASARIPTRHGEFTAVGYRSIYDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG++ GP+ DG DVLVRVHSECLTGDVFGS RCDCGPQLDAAL MVA+EGRGVVLYMR Sbjct 241 LVRGDLPGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL+LGLPADARDYGIGAQILVDLG+ SMRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF 411 NNPAKRVGLDGYGL I ERV +P+RANAEN+ YL TKRD++GHDL GLDDF Sbjct 361 NNPAKRVGLDGYGLQITERVSMPLRANAENLTYLRTKRDRMGHDLIGLDDF 411 >gi|312139595|ref|YP_004006931.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii ribba [Rhodococcus equi 103S] gi|311888934|emb|CBH48247.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II RibBA [Rhodococcus equi 103S] Length=415 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/411 (86%), Positives = 381/411 (93%), Gaps = 2/411 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR DS+ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRFDSIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG CDRLGL PMYA NQDKHGTAYTVTVDAR GIGTGISASDRA TMRLLADPT+ A+ Sbjct 61 LDGEDCDRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPTTGAN 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLARMA L+PAG ICEIVSQKDEG MA DE Sbjct 121 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAKVDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLI WRRKHEKH+ RVAEARIPTRHG+F A+GY SIY++VEHVA Sbjct 181 LRVFADDHDLALISIADLIAWRRKHEKHVVRVAEARIPTRHGDFTAVGYKSIYDEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG+IA DG DVLVRVHSECLTGDVFGS RCDCGPQLDAAL M+A+EGRGVVLYMR Sbjct 241 LVRGDIA--EGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMIAQEGRGVVLYMR 298 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL+LGLPADARDYGIGAQILVDLG++SMRLLT Sbjct 299 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLQLGLPADARDYGIGAQILVDLGIKSMRLLT 358 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF 411 NNPAKRVGLDGYGL I +RVP+P+RANAEN+ YL TKRD++GHDL GLD+F Sbjct 359 NNPAKRVGLDGYGLQITDRVPMPLRANAENLTYLRTKRDRMGHDLIGLDEF 409 >gi|325676730|ref|ZP_08156404.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Rhodococcus equi ATCC 33707] gi|325552512|gb|EGD22200.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Rhodococcus equi ATCC 33707] Length=420 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/411 (86%), Positives = 381/411 (93%), Gaps = 2/411 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 +TR DS+ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 6 VTRFDSIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 65 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDG CDRLGL PMYA NQDKHGTAYTVTVDAR GIGTGISASDRA TMRLLADPT+ A+ Sbjct 66 LDGEDCDRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPTTGAN 125 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLARMA L+PAG ICEIVSQKDEG MA DE Sbjct 126 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAKVDE 185 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLI WRRKHEKH+ RVAEARIPTRHG+F A+GY SIY++VEHVA Sbjct 186 LRVFADDHDLALISIADLIAWRRKHEKHVVRVAEARIPTRHGDFTAVGYKSIYDEVEHVA 245 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG+IA DG DVLVRVHSECLTGDVFGS RCDCGPQLDAAL M+A+EGRGVVLYMR Sbjct 246 LVRGDIA--EGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMIAQEGRGVVLYMR 303 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL+LGLPADARDYGIGAQILVDLG++SMRLLT Sbjct 304 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLQLGLPADARDYGIGAQILVDLGIKSMRLLT 363 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF 411 NNPAKRVGLDGYGL I +RVP+P+RANAEN+ YL TKRD++GHDL GLD+F Sbjct 364 NNPAKRVGLDGYGLQITDRVPMPLRANAENLTYLRTKRDRMGHDLIGLDEF 414 >gi|262202282|ref|YP_003273490.1| GTP cyclohydrolase II [Gordonia bronchialis DSM 43247] gi|262085629|gb|ACY21597.1| GTP cyclohydrolase II [Gordonia bronchialis DSM 43247] Length=442 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/408 (85%), Positives = 378/408 (93%), Gaps = 2/408 (0%) Query 2 TRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPL 61 TR D++ERA+ADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLC PL Sbjct 20 TRFDTIERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCAPL 79 Query 62 DGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADD 121 DG CDRLGL PMY++NQDKHGTAYTVTVDAR GIGTGISASDRATTMRLLADP S A D Sbjct 80 DGDTCDRLGLPPMYSMNQDKHGTAYTVTVDAREGIGTGISASDRATTMRLLADPASSAAD 139 Query 122 FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDEL 181 FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLAR+AGL PAG ICEIVSQKD GSMA TDEL Sbjct 140 FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARLAGLTPAGVICEIVSQKDVGSMAQTDEL 199 Query 182 RVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVAL 241 RVFADEH LALI+IADLI WRR+HEKH+ RVA+ARIPTRHG+FRA+GY+S+Y++VEHVAL Sbjct 200 RVFADEHELALISIADLIAWRRRHEKHVVRVADARIPTRHGDFRAVGYSSVYDEVEHVAL 259 Query 242 VRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRG 301 V G+IA DG DVLVRVHSECLTGDVFGS RCDCGPQLDAA+ MVA EGRG+VLYMRG Sbjct 260 VMGDIAA--GDGHDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEMVAAEGRGIVLYMRG 317 Query 302 HEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTN 361 HEGRGIGL+HKLQAYQLQDAG+DTVDANL+LGLPAD+RDYG+GAQILVDLGV SMRLLTN Sbjct 318 HEGRGIGLLHKLQAYQLQDAGSDTVDANLQLGLPADSRDYGLGAQILVDLGVSSMRLLTN 377 Query 362 NPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLD 409 NPAKRVGLDGYGL I+ERVP+PVRAN EN+RYL TKRD++GHDL GLD Sbjct 378 NPAKRVGLDGYGLQIVERVPMPVRANEENLRYLRTKRDRMGHDLVGLD 425 >gi|343924573|ref|ZP_08764121.1| riboflavin biosynthesis protein RibBA [Gordonia alkanivorans NBRC 16433] gi|343765508|dbj|GAA11047.1| riboflavin biosynthesis protein RibBA [Gordonia alkanivorans NBRC 16433] Length=437 Score = 711 bits (1835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/409 (84%), Positives = 383/409 (94%), Gaps = 2/409 (0%) Query 2 TRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPL 61 +LDS+ERA+ADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVPL Sbjct 17 VQLDSIERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPL 76 Query 62 DGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADD 121 DG CDRLGL PMY++NQDKHGTAYTVTVDAR GIGTGISASDRATTMRLLADP + A D Sbjct 77 DGDACDRLGLPPMYSMNQDKHGTAYTVTVDAREGIGTGISASDRATTMRLLADPEATAGD 136 Query 122 FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDEL 181 FTRPGHVVPLRAK+GGVLRRPGHTEAAVDLAR+A L PAG ICEIVSQKD GSMA +DEL Sbjct 137 FTRPGHVVPLRAKEGGVLRRPGHTEAAVDLARLADLAPAGVICEIVSQKDVGSMARSDEL 196 Query 182 RVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVAL 241 RVFADEH LA+I+IADLI WRR+HEKH+ RVA+ARIPTRHG+FRA+GY+S+Y+DVEHVAL Sbjct 197 RVFADEHDLAMISIADLIAWRRRHEKHVVRVADARIPTRHGDFRAVGYSSVYDDVEHVAL 256 Query 242 VRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRG 301 V+G+++ + DG DVLVRVHSECLTGDVFGS RCDCGPQLDAA+ MVA EGRG++LYMRG Sbjct 257 VKGDVS--SDDGHDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEMVAEEGRGIILYMRG 314 Query 302 HEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTN 361 HEGRGIGL+HKLQAYQLQDAGADTVDANL+LGLPAD+RDYG+GAQILVDLGV SMRLLTN Sbjct 315 HEGRGIGLLHKLQAYQLQDAGADTVDANLELGLPADSRDYGLGAQILVDLGVSSMRLLTN 374 Query 362 NPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDD 410 NPAKRVGLDGYGLHI++RVP+PVRANAEN+RYL TKRD++GHDL GLDD Sbjct 375 NPAKRVGLDGYGLHIVDRVPMPVRANAENLRYLRTKRDRMGHDLVGLDD 423 >gi|296140260|ref|YP_003647503.1| GTP cyclohydrolase II [Tsukamurella paurometabola DSM 20162] gi|296028394|gb|ADG79164.1| GTP cyclohydrolase II [Tsukamurella paurometabola DSM 20162] Length=415 Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/413 (83%), Positives = 372/413 (91%), Gaps = 2/413 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR DS+ERA+ DIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVP Sbjct 1 MTRFDSIERAIEDIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA CD+LGL PMYA NQDKHGTAYTVTVDA+ G+GTGISA+DRATTM LADP S D Sbjct 61 LDGATCDKLGLPPMYATNQDKHGTAYTVTVDAKAGVGTGISAADRATTMLKLADPDSTVD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGVLRRPGHTEAAVDLA MAGL PAG ICEIVS+KD G MA TDE Sbjct 121 DFTRPGHVVPLRAKEGGVLRRPGHTEAAVDLATMAGLAPAGVICEIVSEKDPGGMAQTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IADLI WRRKHEKH+ +VA ARIPT HG+F+A+GYTSI++DVEHVA Sbjct 181 LRVFADDHDLALISIADLIAWRRKHEKHVVQVASARIPTAHGDFQAVGYTSIHDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV+G+I G DVLVRVHSECLTGDVFGS RCDCGPQLDAA+ MVA+EGRGVVLYMR Sbjct 241 LVKGDITADG--GADVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEMVAQEGRGVVLYMR 298 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQD GADTVDANL+LGLPADARDYG+GAQILVDLG+ SMRLLT Sbjct 299 GHEGRGIGLMHKLQAYQLQDGGADTVDANLQLGLPADARDYGLGAQILVDLGITSMRLLT 358 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 NNPAKRVGLDGYGL I ERVP+P+RANAENI YL TKRD++GHD+ LD F + Sbjct 359 NNPAKRVGLDGYGLQITERVPMPLRANAENIHYLRTKRDRMGHDMRDLDHFDQ 411 >gi|326382174|ref|ZP_08203866.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Gordonia neofelifaecis NRRL B-59395] gi|326198904|gb|EGD56086.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Gordonia neofelifaecis NRRL B-59395] Length=431 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/420 (82%), Positives = 372/420 (89%), Gaps = 8/420 (1%) Query 4 LDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 63 D+VERA+ADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFMVRYTSGYLCVPL G Sbjct 15 FDTVERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLAG 74 Query 64 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 123 CDRLGL PMY+VNQDKHGTAYTVTVDAR IGTGISA+DRATTMR LADP S A DFT Sbjct 75 DDCDRLGLPPMYSVNQDKHGTAYTVTVDAREDIGTGISAADRATTMRKLADPGSEAHDFT 134 Query 124 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 183 RPGHVVPLRAK+GGVLRRPGHTEAAVDLA AGL PAG ICEIVSQKD G MA TDELRV Sbjct 135 RPGHVVPLRAKEGGVLRRPGHTEAAVDLATAAGLAPAGVICEIVSQKDPGHMARTDELRV 194 Query 184 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 243 FADEH LALI+IADLI WRR +EKH+E+VA+ARIPT +G FRA+GY S Y+D EH+ALV Sbjct 195 FADEHELALISIADLISWRRHNEKHVEKVADARIPTEYGTFRAVGYQSPYDDAEHIALVM 254 Query 244 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 303 G++A +GDDVLVRVHSECLTGDVFGS RCDCGPQL AA+ MV REGRGVVLYMRGHE Sbjct 255 GDVA---ENGDDVLVRVHSECLTGDVFGSLRCDCGPQLQAAMEMVGREGRGVVLYMRGHE 311 Query 304 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 363 GRGIGLMHKLQAYQLQD+GADTVDANL+LGLPADARDYG+GAQILVDLGVRSMRLLTNNP Sbjct 312 GRGIGLMHKLQAYQLQDSGADTVDANLELGLPADARDYGLGAQILVDLGVRSMRLLTNNP 371 Query 364 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGG 423 AKRVGLDGYGL I++RVP+PVRANAEN+RYL TKRD++GH L GLDD LP GG Sbjct 372 AKRVGLDGYGLEIVDRVPMPVRANAENLRYLRTKRDRMGHVLDGLDDI-----LPEAAGG 426 >gi|333919549|ref|YP_004493130.1| GTP cyclohydrolase-2 [Amycolicicoccus subflavus DQS3-9A1] gi|333481770|gb|AEF40330.1| GTP cyclohydrolase-2 [Amycolicicoccus subflavus DQS3-9A1] Length=422 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/419 (79%), Positives = 374/419 (90%), Gaps = 0/419 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M R DSVERA+ADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE++AFMVRYTSGY+CVP Sbjct 1 MIRFDSVERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYVCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGA CDRLGL PM+A NQDKH TAYTVTVDA+ G+GTGISA+DR+ T +LLADP + + Sbjct 61 LDGADCDRLGLPPMFATNQDKHQTAYTVTVDAKEGVGTGISAADRSITCQLLADPAARPE 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAK+GGV+RR GHTEAAVDL+R+AGL+PAG ICEIVSQKDEG MA DE Sbjct 121 DFTRPGHVVPLRAKEGGVMRRAGHTEAAVDLSRLAGLRPAGVICEIVSQKDEGYMAKADE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LA+I+IADLI WRRK+EKH+ RVA+ARIPT +GEFRA+G+ SIY++VEHVA Sbjct 181 LRVFADDHNLAMISIADLISWRRKNEKHVVRVADARIPTPYGEFRAVGFRSIYDEVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV G+I GP+ G DVLVRVHSECLTGD+FGS RCDCGPQLDAA+ MVA EGRGVVLYMR Sbjct 241 LVLGDIPGPDGKGTDVLVRVHSECLTGDIFGSLRCDCGPQLDAAMRMVAEEGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQDAG+DTVDANL LGLPADARDYGIGAQILVDLGV +MRLLT Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGSDTVDANLALGLPADARDYGIGAQILVDLGVTTMRLLT 360 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPG 419 NNPAKR GLDGYGL I +RVP+P+RAN ENI YL TKRD++GH+L GLD+ + + G Sbjct 361 NNPAKRAGLDGYGLAISDRVPMPIRANKENIHYLRTKRDRMGHELEGLDEHFDPRGIEG 419 >gi|54025570|ref|YP_119812.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Nocardia farcinica IFM 10152] gi|81602604|sp|Q5YTP3.1|RIBBA_NOCFA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes: RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase; Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2; AltName: Full=GTP cyclohydrolase II gi|54017078|dbj|BAD58448.1| putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Nocardia farcinica IFM 10152] Length=414 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/403 (84%), Positives = 366/403 (91%), Gaps = 4/403 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTR D++ERAVADIAAGKAV+V+DDEDRENEGDLIFAAEKATPE+VAFM+RYTSGY+CVP Sbjct 1 MTRFDTIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMIRYTSGYICVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L G CDRLGL PMYA NQDKHGTAYTV+VDAR GI TGISA+DRATTMRLLAD + AD Sbjct 61 LTGEDCDRLGLPPMYATNQDKHGTAYTVSVDAREGITTGISAADRATTMRLLADADAKAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 D TRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGL+PAG ICEIVSQKDEG MA T+E Sbjct 121 DLTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLRPAGVICEIVSQKDEGHMARTEE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFAD+H LALI+IAD+I WRRKHEK + RVAEARIPT HG F A+GY SIY+DVEHVA Sbjct 181 LRVFADDHDLALISIADMIAWRRKHEKQVVRVAEARIPTAHGAFTAVGYQSIYDDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRG+I DG+DVLVRVHSECLTGDVFGS RCDCGPQLDAAL MV +EGRGVVLYMR Sbjct 241 LVRGDI----GDGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAALEMVDQEGRGVVLYMR 296 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLMHKLQAYQLQD+G DTVDANL LGLPADARDYG GAQILVDLG+RSMRLLT Sbjct 297 GHEGRGIGLMHKLQAYQLQDSGRDTVDANLDLGLPADARDYGTGAQILVDLGIRSMRLLT 356 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGH 403 NNPAKRVGLDGYGL I ERVP+P+RANAEN+RYL TKRD++GH Sbjct 357 NNPAKRVGLDGYGLTITERVPMPLRANAENLRYLRTKRDRMGH 399 >gi|289442860|ref|ZP_06432604.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis T46] gi|289415779|gb|EFD13019.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis T46] Length=397 Score = 664 bits (1714), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/332 (99%), Positives = 331/332 (99%), Gaps = 0/332 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP Sbjct 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD Sbjct 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE Sbjct 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA Sbjct 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR Sbjct 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKL 332 GHEGRGIGLMHKLQAYQLQDAGADTVDANL L Sbjct 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLSL 332 >gi|317508956|ref|ZP_07966589.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Segniliparus rugosus ATCC BAA-974] gi|316252721|gb|EFV12158.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Segniliparus rugosus ATCC BAA-974] Length=414 Score = 637 bits (1642), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 309/410 (76%), Positives = 360/410 (88%), Gaps = 4/410 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M+ DS+ERA+ DIA GKA++V+DDEDRENEGDL FAAEKATPE+VAFM+R+TSGYLCVP Sbjct 1 MSEFDSIERAIKDIAEGKAIVVVDDEDRENEGDLTFAAEKATPELVAFMIRHTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 ++ CDRL L PMYAVNQD+ GTAYTVTVDAR G+GTGISA DRA T++LLA+ + A Sbjct 61 MEEEDCDRLDLPPMYAVNQDRRGTAYTVTVDAREGVGTGISARDRAHTIQLLANAETKAS 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 D TRPGH+VPLRAK GGVLRRPGHTEAAVDLAR+AGL+PAG ICEIVS KDE MA DE Sbjct 121 DLTRPGHMVPLRAKPGGVLRRPGHTEAAVDLARLAGLRPAGVICEIVSTKDEEHMAKGDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFA+EH LA I+IADLI +RR++EKH+ R AEAR+PTRHG FRAIGY+ YED EH+A Sbjct 181 LRVFAEEHNLARISIADLIRYRRRYEKHVRREAEARLPTRHGVFRAIGYSCAYEDAEHMA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 +V G+I ++G+DVLVRVHSECLTGDVFGS RCDCGPQLDAA+ +VA EGRGVVLYMR Sbjct 241 MVFGDI----SNGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEIVAEEGRGVVLYMR 296 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+ KL+AY+LQD GADTVDANL+LGLPADARDYG+GAQIL DLG+RSMRLLT Sbjct 297 GHEGRGIGLLAKLRAYELQDGGADTVDANLQLGLPADARDYGVGAQILCDLGIRSMRLLT 356 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDD 410 NNPAKRVGLDGYGL I +RVP+P+RANAEN+RYL TKRD++GH+L GL++ Sbjct 357 NNPAKRVGLDGYGLTIHDRVPMPMRANAENLRYLQTKRDRMGHELDGLEE 406 >gi|296395031|ref|YP_003659915.1| GTP cyclohydrolase II [Segniliparus rotundus DSM 44985] gi|296182178|gb|ADG99084.1| GTP cyclohydrolase II [Segniliparus rotundus DSM 44985] Length=414 Score = 632 bits (1629), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 304/410 (75%), Positives = 360/410 (88%), Gaps = 4/410 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M+ DS+ERA+ DIA GKAV+V+DDE+RENEGDL FAAEKAT E+VAFM+R+TSGYLCVP Sbjct 1 MSGFDSIERAIKDIADGKAVVVVDDEERENEGDLTFAAEKATSELVAFMIRHTSGYLCVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 ++ CDRL L PMY VNQD+ GTAYTVTVDA++G+GTGISA DRA T+RLLADP + + Sbjct 61 MEEEDCDRLDLPPMYTVNQDRRGTAYTVTVDAKDGVGTGISAKDRAHTIRLLADPRTKSA 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 D TRPGH+VPLRAK GGV+RRPGHTEAAVDLAR+AGL+P G ICEIVS KDE MA DE Sbjct 121 DLTRPGHMVPLRAKPGGVMRRPGHTEAAVDLARLAGLRPVGVICEIVSTKDEEHMAKGDE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LRVFA+EH LA ++IADLI +RR++EKH+ R A+AR+PTRHG F++IGY+ YED EHVA Sbjct 181 LRVFAEEHNLARVSIADLIRYRRRYEKHVRREAQARLPTRHGVFQSIGYSCAYEDAEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 +V G+I DG+DVLVRVHSECLTGDVFGS RCDCGPQLDAA+ ++A EGRGVVLYMR Sbjct 241 MVFGDI----GDGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEIIAAEGRGVVLYMR 296 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKL+AY+LQD GADTVDANL+LGLPAD+RDYG+GAQILVDLG+RSMRLLT Sbjct 297 GHEGRGIGLLHKLRAYELQDGGADTVDANLQLGLPADSRDYGVGAQILVDLGIRSMRLLT 356 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDD 410 NNPAKRVGLDGYGL I +RVP+P+RANAEN+RYL TKRD++GH+L GL++ Sbjct 357 NNPAKRVGLDGYGLTIHDRVPMPMRANAENLRYLQTKRDRMGHELEGLEE 406 >gi|257055603|ref|YP_003133435.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Saccharomonospora viridis DSM 43017] gi|256585475|gb|ACU96608.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase [Saccharomonospora viridis DSM 43017] Length=438 Score = 620 bits (1599), Expect = 1e-175, Method: Compositional matrix adjust. Identities = 307/410 (75%), Positives = 346/410 (85%), Gaps = 4/410 (0%) Query 4 LDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 63 ++S+ERA+ DIA G+ V+V+DDEDRENEGDLIFAAEKATPE++AFMVRYTSGY+CV L G Sbjct 12 IESIERAIEDIANGRPVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICVALTG 71 Query 64 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 123 CDRL L PMY NQD+ GTAYTVTVDA GIGTGISA+DR T+RLLADP S A D T Sbjct 72 EDCDRLDLPPMYHSNQDRRGTAYTVTVDAAEGIGTGISATDRCHTIRLLADPNSKASDLT 131 Query 124 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 183 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGL PAG +CEIVSQK+EG MA DEL V Sbjct 132 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLAPAGVLCEIVSQKNEGDMARRDELEV 191 Query 184 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 243 FA +H L LITIADLI +R++ EK +ERVAEARIP G FRAIGY S+ + +EHVA V Sbjct 192 FAADHDLQLITIADLIAYRKRREKQVERVAEARIPLAAGTFRAIGYDSLLDGIEHVAFVY 251 Query 244 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 303 G+I DG+D+LVRVHSECLTGDVFGS RCDCGPQL AAL VA EGRGVVLY+RGHE Sbjct 252 GDI----GDGEDILVRVHSECLTGDVFGSLRCDCGPQLQAALKAVADEGRGVVLYVRGHE 307 Query 304 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 363 GRGIGL+HKLQAY+LQDAGADTVDANL LG+PADARDYG GAQIL DLGVRSMRLLTNNP Sbjct 308 GRGIGLLHKLQAYELQDAGADTVDANLALGVPADARDYGTGAQILSDLGVRSMRLLTNNP 367 Query 364 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 AKRVGL+GYGL ++ RVPLP+ N EN RYL TKRD++GH+L+ L+ F E Sbjct 368 AKRVGLEGYGLRVVGRVPLPISPNPENFRYLKTKRDRMGHELSQLEHFDE 417 >gi|302525889|ref|ZP_07278231.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Streptomyces sp. AA4] gi|302434784|gb|EFL06600.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Streptomyces sp. AA4] Length=420 Score = 612 bits (1578), Expect = 4e-173, Method: Compositional matrix adjust. Identities = 303/410 (74%), Positives = 346/410 (85%), Gaps = 4/410 (0%) Query 4 LDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 63 +D+VE A+ADIAAG+AV+V+DDEDRENEGDLIFAAEKATPE++AFMVRYTSGY+CVPL Sbjct 1 MDAVEAAIADIAAGRAVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICVPLTE 60 Query 64 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 123 A DRL L PM+ NQD GTAY+VTVDA GI TGISA DRA T+RLLADP + A DF Sbjct 61 AEADRLDLPPMFHTNQDARGTAYSVTVDAAEGISTGISAVDRAHTIRLLADPEATAKDFR 120 Query 124 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 183 RPGHVVPLRAK+GGVLRRPGHTEAA+DLAR+AGL PAG +CEIVSQKDEG MA DEL V Sbjct 121 RPGHVVPLRAKEGGVLRRPGHTEAAIDLARLAGLHPAGVLCEIVSQKDEGDMARRDELEV 180 Query 184 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 243 FA +H L +I+IA+LI +RR+ EK +ERVAEARIP G FRA+GY S+ + +EHVA V Sbjct 181 FAADHDLKIISIAELIAYRRRTEKQVERVAEARIPLAAGTFRAVGYDSLLDGIEHVAFVY 240 Query 244 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 303 GEI DG+D+LVRVHSECLTGDVFGS RCDCGPQLDAAL VA EGRGVVLY+RGHE Sbjct 241 GEI----GDGEDILVRVHSECLTGDVFGSLRCDCGPQLDAALQKVADEGRGVVLYIRGHE 296 Query 304 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 363 GRGIGL+HKLQAYQLQDAGADTVDANL LG+PADARDYG GAQIL DLGVRSMRLLTNNP Sbjct 297 GRGIGLLHKLQAYQLQDAGADTVDANLALGVPADARDYGTGAQILCDLGVRSMRLLTNNP 356 Query 364 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 AKRVGL+GYGL + RV LP+ N EN+RYL TKRD++GHDL+ L+ + + Sbjct 357 AKRVGLEGYGLRVTGRVALPISPNPENLRYLRTKRDRMGHDLSQLEHYDQ 406 >gi|291003620|ref|ZP_06561593.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Saccharopolyspora erythraea NRRL 2338] Length=438 Score = 610 bits (1572), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 305/420 (73%), Positives = 347/420 (83%), Gaps = 5/420 (1%) Query 3 RLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLD 62 + D +ERA+ADIAAG+ VIV+DDEDRENEGDLIFAAE ATPEMVAFMVRYTSGY+CV L Sbjct 21 KFDDIERALADIAAGRPVIVVDDEDRENEGDLIFAAEMATPEMVAFMVRYTSGYICVALT 80 Query 63 GAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDF 122 G CDRL L PMY NQD+ GTAYTVTVDA G+ TGISASDRA T+++LA S ADD Sbjct 81 GEDCDRLDLPPMYHWNQDRKGTAYTVTVDAAEGVSTGISASDRAHTLKVLAHADSSADDL 140 Query 123 TRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELR 182 RPGHVVPLRA+DGGVLRRPGHTEAAVDL+R+AGL+PAGA+CEIVSQK EG MA DEL Sbjct 141 NRPGHVVPLRARDGGVLRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELE 200 Query 183 VFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALV 242 VFADEH LALITIADLI +RR+ E+ + RVAEARIPT HG FR +GY S + +EH+ALV Sbjct 201 VFADEHDLALITIADLIAYRRRFEQQVVRVAEARIPTAHGTFRTVGYDSTLDGIEHLALV 260 Query 243 RGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGH 302 G+I DG+D+LVRVHSECLTGDV GS RCDCGPQL AA+ VA GRGVVLYMRGH Sbjct 261 YGDI----GDGEDILVRVHSECLTGDVLGSLRCDCGPQLAAAMEKVAEAGRGVVLYMRGH 316 Query 303 EGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNN 362 EGRGIGLMHKLQAYQLQD GADTVDAN+ LG+P D RDYG GAQIL DLG++SMRLLTNN Sbjct 317 EGRGIGLMHKLQAYQLQDDGADTVDANVALGMPVDGRDYGQGAQILCDLGIKSMRLLTNN 376 Query 363 PAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFG 422 PAKRVGL+GYGL ++ R PLP+R N EN+RYL TKRD++GH+L L+D +S L GE G Sbjct 377 PAKRVGLEGYGLRVVGREPLPIRPNPENLRYLQTKRDRMGHELYDLEDGEDS-SLGGEAG 435 >gi|134098693|ref|YP_001104354.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Saccharopolyspora erythraea NRRL 2338] gi|133911316|emb|CAM01429.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Saccharopolyspora erythraea NRRL 2338] Length=437 Score = 609 bits (1571), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 305/420 (73%), Positives = 347/420 (83%), Gaps = 5/420 (1%) Query 3 RLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLD 62 + D +ERA+ADIAAG+ VIV+DDEDRENEGDLIFAAE ATPEMVAFMVRYTSGY+CV L Sbjct 20 KFDDIERALADIAAGRPVIVVDDEDRENEGDLIFAAEMATPEMVAFMVRYTSGYICVALT 79 Query 63 GAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDF 122 G CDRL L PMY NQD+ GTAYTVTVDA G+ TGISASDRA T+++LA S ADD Sbjct 80 GEDCDRLDLPPMYHWNQDRKGTAYTVTVDAAEGVSTGISASDRAHTLKVLAHADSSADDL 139 Query 123 TRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELR 182 RPGHVVPLRA+DGGVLRRPGHTEAAVDL+R+AGL+PAGA+CEIVSQK EG MA DEL Sbjct 140 NRPGHVVPLRARDGGVLRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELE 199 Query 183 VFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALV 242 VFADEH LALITIADLI +RR+ E+ + RVAEARIPT HG FR +GY S + +EH+ALV Sbjct 200 VFADEHDLALITIADLIAYRRRFEQQVVRVAEARIPTAHGTFRTVGYDSTLDGIEHLALV 259 Query 243 RGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGH 302 G+I DG+D+LVRVHSECLTGDV GS RCDCGPQL AA+ VA GRGVVLYMRGH Sbjct 260 YGDI----GDGEDILVRVHSECLTGDVLGSLRCDCGPQLAAAMEKVAEAGRGVVLYMRGH 315 Query 303 EGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNN 362 EGRGIGLMHKLQAYQLQD GADTVDAN+ LG+P D RDYG GAQIL DLG++SMRLLTNN Sbjct 316 EGRGIGLMHKLQAYQLQDDGADTVDANVALGMPVDGRDYGQGAQILCDLGIKSMRLLTNN 375 Query 363 PAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFG 422 PAKRVGL+GYGL ++ R PLP+R N EN+RYL TKRD++GH+L L+D +S L GE G Sbjct 376 PAKRVGLEGYGLRVVGREPLPIRPNPENLRYLQTKRDRMGHELYDLEDGEDS-SLGGEAG 434 >gi|300784679|ref|YP_003764970.1| GTP cyclohydrolase II/3,4-dihydroxy 2-butanone 4-phosphate synthase [Amycolatopsis mediterranei U32] gi|299794193|gb|ADJ44568.1| GTP cyclohydrolase II/3,4-dihydroxy 2-butanone 4-phosphate synthase [Amycolatopsis mediterranei U32] gi|340526102|gb|AEK41307.1| GTP cyclohydrolase II/3,4-dihydroxy 2-butanone 4-phosphate synthase [Amycolatopsis mediterranei S699] Length=442 Score = 598 bits (1541), Expect = 7e-169, Method: Compositional matrix adjust. Identities = 302/409 (74%), Positives = 345/409 (85%), Gaps = 4/409 (0%) Query 5 DSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGA 64 D++ERA++DIAAG+ V+V+DDEDRENEGDLIFAAEKATPE++AFMVRYTSGY+CV L + Sbjct 25 DAIERAISDIAAGRPVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYVCVALTES 84 Query 65 ICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTR 124 DRL L PMY NQD GTAY+VTVDA GI TGISA+DRA T+RLLADP S A DF R Sbjct 85 EADRLDLPPMYHTNQDARGTAYSVTVDAAEGISTGISAADRAHTIRLLADPASTAKDFRR 144 Query 125 PGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVF 184 PGHVVPLRAK+GGVLRRPGHTEA+VDLARMAGL PAG +CEIVSQKDEG MA DEL VF Sbjct 145 PGHVVPLRAKEGGVLRRPGHTEASVDLARMAGLAPAGVLCEIVSQKDEGDMARRDELEVF 204 Query 185 ADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRG 244 A +H LA+ITIADLI +RR+ EK +ERVAEARIP G FRA+GY S+ + +EHVA V G Sbjct 205 AADHDLAIITIADLIAYRRRTEKQVERVAEARIPLAAGTFRAVGYDSLLDGIEHVAFVYG 264 Query 245 EIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEG 304 EI DG D+LVRVHSECLTGDVFGS RCDCGPQL+AAL VA EGRGVVLY+RGHEG Sbjct 265 EI----GDGQDILVRVHSECLTGDVFGSLRCDCGPQLEAALEAVAAEGRGVVLYIRGHEG 320 Query 305 RGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPA 364 RGIGL+HKLQAYQLQD GADTVDANL LG+PADARDYG GAQIL DLGVR+MRLL+NNPA Sbjct 321 RGIGLLHKLQAYQLQDDGADTVDANLALGVPADARDYGTGAQILCDLGVRTMRLLSNNPA 380 Query 365 KRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 KR+GL+GYGL + RVPLP+ N EN+RYL TKRD++GHDLA L+ + + Sbjct 381 KRIGLEGYGLRVTGRVPLPISPNPENLRYLRTKRDRMGHDLAQLEHYDQ 429 >gi|256379225|ref|YP_003102885.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Actinosynnema mirum DSM 43827] gi|255923528|gb|ACU39039.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Actinosynnema mirum DSM 43827] Length=417 Score = 595 bits (1535), Expect = 4e-168, Method: Compositional matrix adjust. Identities = 306/405 (76%), Positives = 341/405 (85%), Gaps = 4/405 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M R +ERAVAD+AAG+ VIV+DDEDRENEGDLIFAAEKATPE+VAFMVR+TSGY+CV Sbjct 1 MNRFADIERAVADVAAGRPVIVVDDEDRENEGDLIFAAEKATPELVAFMVRHTSGYICVS 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L A C RL L PMY NQD+ GTAY VTVDA+ G TGISA+DRA T+RLLAD T+ Sbjct 61 LTEADCVRLDLPPMYHTNQDERGTAYAVTVDAKQGGTTGISAADRARTIRLLADATATPA 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 FTRPGHVVPLRA+DGGVLRR GHTEAAVDL+R+AGL P G +CEIVSQKDEG MA +E Sbjct 121 HFTRPGHVVPLRARDGGVLRRTGHTEAAVDLSRLAGLAPVGVLCEIVSQKDEGDMAQREE 180 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 L VFA EH LALITIADL+ +RR+ E ++RVAEARIPT HG FRA GY S + +EHVA Sbjct 181 LEVFAAEHDLALITIADLVAYRRRVEVQVQRVAEARIPTAHGVFRAYGYDSKVDGIEHVA 240 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV GE+ DG++VLVRVHSECLTGDV GS RCDCGPQLDAALA VA EGRGVVLYMR Sbjct 241 LVCGEV----GDGEEVLVRVHSECLTGDVLGSLRCDCGPQLDAALAAVAAEGRGVVLYMR 296 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKLQAYQLQDAGADTVDANL LGLPADARDYG GAQILVDLGVRSMRLLT Sbjct 297 GHEGRGIGLVHKLQAYQLQDAGADTVDANLDLGLPADARDYGTGAQILVDLGVRSMRLLT 356 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDL 405 NNPAKRVGL+GYGL + +RVPLPV N EN+RYL TKRD++GH+L Sbjct 357 NNPAKRVGLEGYGLRVADRVPLPVSPNPENLRYLRTKRDRMGHEL 401 >gi|331697231|ref|YP_004333470.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Pseudonocardia dioxanivorans CB1190] gi|326951920|gb|AEA25617.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Pseudonocardia dioxanivorans CB1190] Length=437 Score = 593 bits (1530), Expect = 1e-167, Method: Compositional matrix adjust. Identities = 299/410 (73%), Positives = 346/410 (85%), Gaps = 0/410 (0%) Query 4 LDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDG 63 + +ERAVAD+A GK V+V+DDEDRENEGDLIFAAEKATPE+V+F+VRYTSGY+CV L Sbjct 19 FELIERAVADLAEGKPVVVVDDEDRENEGDLIFAAEKATPELVSFVVRYTSGYVCVALTE 78 Query 64 AICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFT 123 CDRL L PM+ N D TA+TVTVDA+ G+ TGISA+DRA T+RLLADP + D Sbjct 79 EDCDRLDLPPMHHTNTDNFRTAFTVTVDAKEGVTTGISAADRARTIRLLADPAAAPADLV 138 Query 124 RPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRV 183 RPGHV+PLRA++GGVLRRPGHTEAAVDLARMAGL PAGA+CEIVSQKD+ MA DEL+V Sbjct 139 RPGHVLPLRAREGGVLRRPGHTEAAVDLARMAGLSPAGALCEIVSQKDDTDMARGDELQV 198 Query 184 FADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVR 243 FA++H L LITIADLI +RR+ EKHI RVA+ARIPTRHG+F A GY S+ + +EH+A+V Sbjct 199 FAEDHELTLITIADLIAYRRRFEKHIVRVAQARIPTRHGDFIAYGYDSLLDGIEHIAMVV 258 Query 244 GEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHE 303 G++A P DG+DVLVRVHSECLTGDV GS RCDCGPQLDAAL VAREGRG+VLYMRGHE Sbjct 259 GDVATPEGDGEDVLVRVHSECLTGDVLGSLRCDCGPQLDAALEAVAREGRGIVLYMRGHE 318 Query 304 GRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNP 363 GRGIGL+HKLQAYQLQ+AGADTVDANL +GLPADARDYGIGAQIL DLGVRSMRLLTNNP Sbjct 319 GRGIGLLHKLQAYQLQEAGADTVDANLAMGLPADARDYGIGAQILADLGVRSMRLLTNNP 378 Query 364 AKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 KR GL+GYGL I RVP+P+R EN+RYL TKRD++GH+L GL D E Sbjct 379 DKRAGLEGYGLTINGRVPMPIRPTPENLRYLRTKRDRMGHELPGLGDAPE 428 >gi|298524920|ref|ZP_07012329.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium tuberculosis 94_M4241A] gi|298494714|gb|EFI30008.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium tuberculosis 94_M4241A] Length=295 Score = 593 bits (1529), Expect = 2e-167, Method: Compositional matrix adjust. Identities = 294/295 (99%), Positives = 295/295 (100%), Gaps = 0/295 (0%) Query 131 LRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGL 190 +RAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGL Sbjct 1 MRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGL 60 Query 191 ALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPN 250 ALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPN Sbjct 61 ALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPN 120 Query 251 ADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLM 310 ADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLM Sbjct 121 ADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLM 180 Query 311 HKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLD 370 HKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLD Sbjct 181 HKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLD 240 Query 371 GYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL 425 GYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL Sbjct 241 GYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL 295 >gi|336179148|ref|YP_004584523.1| GTP cyclohydrolase-2 [Frankia symbiont of Datisca glomerata] gi|334860128|gb|AEH10602.1| GTP cyclohydrolase-2 [Frankia symbiont of Datisca glomerata] Length=475 Score = 586 bits (1511), Expect = 2e-165, Method: Compositional matrix adjust. Identities = 291/407 (72%), Positives = 341/407 (84%), Gaps = 6/407 (1%) Query 2 TRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPL 61 TR S++ AVA IAAG+ V+V+DD DRENEGDLIFAAEKATPE++AFM+RYTSG +CVP+ Sbjct 10 TRFASIDEAVAQIAAGRPVVVVDDADRENEGDLIFAAEKATPELLAFMIRYTSGVVCVPM 69 Query 62 DGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADD 121 DGA DRL L M N ++ GTA+TV+VDAR G+ TGISA+DRA T+RLLADP + Sbjct 70 DGADLDRLELDQMVPHNTERMGTAFTVSVDARAGVTTGISAADRALTIRLLADPATTVAH 129 Query 122 FTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDEL 181 T+PGH+ PLRAK GGVLRRPGHTEAAVDLAR+AGL+PAGAICEIV+ D+GSMA EL Sbjct 130 ITKPGHIFPLRAKVGGVLRRPGHTEAAVDLARLAGLRPAGAICEIVN--DDGSMARLPEL 187 Query 182 RVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVAL 241 FA+EHGL LI+IADL+ +RR+ E H+E+VA+ RIPT +GEFRA GY + EDVEHVAL Sbjct 188 TRFAEEHGLLLISIADLVAYRRRSEHHVEQVADTRIPTGYGEFRAFGYRGVIEDVEHVAL 247 Query 242 VRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRG 301 V+G+I DG DVLVRVHSECLTGDVFGSRRCDCG QLDAAL M+A+EGRGVVLYMRG Sbjct 248 VKGDIG----DGRDVLVRVHSECLTGDVFGSRRCDCGTQLDAALRMIAQEGRGVVLYMRG 303 Query 302 HEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTN 361 HEGRG+GL+HKL+AYQ+QDAG DTVDANL LGLPADARDYG GAQILVDLG+R+MRLLTN Sbjct 304 HEGRGVGLIHKLRAYQMQDAGHDTVDANLALGLPADARDYGTGAQILVDLGIRTMRLLTN 363 Query 362 NPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGL 408 NP KR GL+GYGL ++ERV LPV EN+RYL TKRD++GHDL GL Sbjct 364 NPTKRAGLEGYGLEVVERVGLPVNFTPENLRYLTTKRDRMGHDLPGL 410 >gi|324999322|ref|ZP_08120434.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Pseudonocardia sp. P1] Length=449 Score = 583 bits (1504), Expect = 1e-164, Method: Compositional matrix adjust. Identities = 286/406 (71%), Positives = 335/406 (83%), Gaps = 0/406 (0%) Query 3 RLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLD 62 R +E+A+ADIA GK V+V+DDEDRENEGDLIFAA KATPE++AF VRYTSGY+CV + Sbjct 36 RFAQIEKAIADIAEGKPVVVMDDEDRENEGDLIFAAAKATPELLAFTVRYTSGYVCVAIT 95 Query 63 GAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDF 122 C+RL L PM+ N+D TAYTVTVDA+ G+ TGISA DR T++LLADP + + D Sbjct 96 EDTCERLDLPPMHHTNRDSFRTAYTVTVDAKEGVTTGISAQDRCRTIQLLADPATESADL 155 Query 123 TRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELR 182 RPGHV+PL+A++GGVLRRPGHTEAAVDLARMAGL PAGA+CEIVS+K+ G MA +EL Sbjct 156 VRPGHVLPLQAREGGVLRRPGHTEAAVDLARMAGLPPAGALCEIVSEKNAGDMARGEELG 215 Query 183 VFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALV 242 VFA +H L LITIADLI +RR+ EKHIER+A ARIPT HG+F A GY S+ + VEH+A+V Sbjct 216 VFAADHDLTLITIADLIAYRRRFEKHIERIATARIPTGHGDFLAYGYDSLLDGVEHIAMV 275 Query 243 RGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGH 302 G + P DG++VLVRVHSECLTGDV GS RCDCGPQLDAAL VA EGRGVVLYMRGH Sbjct 276 MGPVGTPADDGEEVLVRVHSECLTGDVLGSLRCDCGPQLDAALEAVANEGRGVVLYMRGH 335 Query 303 EGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNN 362 EGRGIGL+HKLQAYQLQ+AGADTVDANL +GLPADARDYGIGAQIL DLGVRSMRLLTNN Sbjct 336 EGRGIGLLHKLQAYQLQEAGADTVDANLAMGLPADARDYGIGAQILADLGVRSMRLLTNN 395 Query 363 PAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGL 408 P KR GL+GYGL ++ R +PVRA +N+RYL TKRD++GHDL L Sbjct 396 PDKRAGLEGYGLRVVGREAMPVRATPQNLRYLRTKRDRMGHDLPDL 441 >gi|158313560|ref|YP_001506068.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein [Frankia sp. EAN1pec] gi|158108965|gb|ABW11162.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Frankia sp. EAN1pec] Length=444 Score = 577 bits (1486), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 292/418 (70%), Positives = 343/418 (83%), Gaps = 9/418 (2%) Query 6 SVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAI 65 ++E A+A+IAAG+ V+V+DD DRENEGDLIFAAE ATPE++AFMVR+T+G +CVPLD A Sbjct 5 TIETAIAEIAAGRPVVVVDDADRENEGDLIFAAEAATPELLAFMVRHTAGVVCVPLDPAE 64 Query 66 CDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRP 125 DRL L M N D+ GTA+T++VDAR+G+ TGISA+DRA T+RLLADP + D TRP Sbjct 65 VDRLDLDQMVPQNTDRMGTAFTISVDARSGVTTGISAADRARTIRLLADPATQPGDLTRP 124 Query 126 GHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFA 185 GH+ PLRAK+GGVLRRPGHTEAAVDLAR+AGL+PAGAICEIV++ +GSMA EL FA Sbjct 125 GHIFPLRAKEGGVLRRPGHTEAAVDLARLAGLRPAGAICEIVNE--DGSMARLPELTAFA 182 Query 186 DEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGE 245 EHGLALI+IADLI +RR+ EK + RVAEARIPTR+G FRA+GY + VEH+AL+RGE Sbjct 183 REHGLALISIADLIAYRRRTEKQVVRVAEARIPTRYGSFRAVGYRGTLDGVEHIALIRGE 242 Query 246 IAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGR 305 + DG++VLVRVHSECLTGDVFGS+RCDCG QLDAAL VA EGRGVVLY+RGHEGR Sbjct 243 VG----DGENVLVRVHSECLTGDVFGSQRCDCGNQLDAALRAVAAEGRGVVLYVRGHEGR 298 Query 306 GIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAK 365 GIGLMHKLQAYQLQDAG DTVDANL LGLPADARDYG GAQILVDLGVR +RLL+NNP K Sbjct 299 GIGLMHKLQAYQLQDAGHDTVDANLALGLPADARDYGTGAQILVDLGVRGLRLLSNNPTK 358 Query 366 RVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGG 423 R GL+GYGL I+E+V LPV EN+RYL TKRD++GHDL GL + LP GG Sbjct 359 RAGLEGYGLRIVEQVGLPVTHTPENLRYLTTKRDRMGHDLPGLPGLPD---LPKVVGG 413 >gi|227488845|ref|ZP_03919161.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase [Corynebacterium glucuronolyticum ATCC 51867] gi|227542160|ref|ZP_03972209.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase [Corynebacterium glucuronolyticum ATCC 51866] gi|227091267|gb|EEI26579.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase [Corynebacterium glucuronolyticum ATCC 51867] gi|227181989|gb|EEI62961.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase [Corynebacterium glucuronolyticum ATCC 51866] Length=431 Score = 576 bits (1484), Expect = 3e-162, Method: Compositional matrix adjust. Identities = 284/415 (69%), Positives = 335/415 (81%), Gaps = 8/415 (1%) Query 3 RLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLD 62 +LD+V+ A+A+IAAGK V+V+DDEDRENEGD+IFAAEKATPE++ F+VRY+SGY+C PL Sbjct 9 KLDTVDEAIAEIAAGKPVVVVDDEDRENEGDIIFAAEKATPELMGFLVRYSSGYVCAPLT 68 Query 63 GAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDF 122 GA CDRL L PM NQD GTAYTVTVDA G TGISA R T+R LA TS DDF Sbjct 69 GADCDRLQLPPMVQNNQDVRGTAYTVTVDAATG-STGISAMSRCETVRRLASATSTPDDF 127 Query 123 TRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELR 182 TRPGHV PLRA++GGVL R GHTEAA+DLAR+AGL+PAG +CE+VS+ D MA ELR Sbjct 128 TRPGHVAPLRAREGGVLVRAGHTEAAIDLARLAGLRPAGVLCEVVSEDDPTDMARLPELR 187 Query 183 VFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALV 242 FAD HGL LI+IA LIEWRR HEK +ERVAE R+PT +G+F+A GYTS+ + VEHVALV Sbjct 188 RFADTHGLKLISIAQLIEWRRAHEKLVERVAETRLPTEYGQFKAYGYTSLVDGVEHVALV 247 Query 243 RGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGH 302 GEI DG+++LVRVHSECLTGDVFGSRRCDCG QL AAL + EGRG++LYMRGH Sbjct 248 AGEIG----DGENILVRVHSECLTGDVFGSRRCDCGQQLHAALKKIQDEGRGILLYMRGH 303 Query 303 EGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNN 362 EGRGIGL+ KL+AYQLQD GADTVDANL LG PADAR+YG GAQIL DLGV+S+RL+TNN Sbjct 304 EGRGIGLLAKLKAYQLQDEGADTVDANLALGFPADAREYGTGAQILADLGVKSLRLITNN 363 Query 363 PAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF---HES 414 P+KRVGLDGYG+ I+ RVP+ V + +N RYL TKRD++GH L LD+F HES Sbjct 364 PSKRVGLDGYGIDIVGRVPISVEVSEDNYRYLETKRDRMGHQLPELDEFAHTHES 418 >gi|302866842|ref|YP_003835479.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Micromonospora aurantiaca ATCC 27029] gi|315503257|ref|YP_004082144.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Micromonospora sp. L5] gi|302569701|gb|ADL45903.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Micromonospora aurantiaca ATCC 27029] gi|315409876|gb|ADU07993.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Micromonospora sp. L5] Length=421 Score = 573 bits (1478), Expect = 2e-161, Method: Compositional matrix adjust. Identities = 290/414 (71%), Positives = 337/414 (82%), Gaps = 6/414 (1%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M+ S+E+AVADIAAG+ V+V+DDEDRENEGDLIFAAE ATPE+VAFMVRYTSGY+CVP Sbjct 1 MSTFGSIEQAVADIAAGRPVVVVDDEDRENEGDLIFAAELATPELVAFMVRYTSGYICVP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L CDRL L PM+ NQD+ GTAYTVTVDAR G+ TGISA+DR+ T+RLLAD + Sbjct 61 LTEDECDRLDLPPMHHTNQDRRGTAYTVTVDAREGVSTGISAADRSHTIRLLADAATGPT 120 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 D RPGHVVPLRA+ GGVLRRPGHTEAAVDL RMAGL+PAG +CE+V+ D+G+M + Sbjct 121 DLARPGHVVPLRARAGGVLRRPGHTEAAVDLTRMAGLRPAGVLCELVN--DDGTMMRLPD 178 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 + F EHGL L+TIADLI RR+ EK +E AEAR+PT +G F+A+GY + ++ EHVA Sbjct 179 MEKFCAEHGLTLVTIADLIAHRRRTEKQVELAAEARMPTPYGVFKALGYRAEHDPAEHVA 238 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV G++ DG DVLVRVHSECLTGDVFGS RCDCGPQL AALA VA+EGRGVVLY+R Sbjct 239 LVMGDLG----DGRDVLVRVHSECLTGDVFGSLRCDCGPQLQAALARVAQEGRGVVLYVR 294 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGL+HKLQAYQLQD G DTVDANL LGLPADARDYG GAQIL DLGVRSMRLLT Sbjct 295 GHEGRGIGLLHKLQAYQLQDQGRDTVDANLDLGLPADARDYGTGAQILYDLGVRSMRLLT 354 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHES 414 NNPAKR GL+GYGL + R LPVR+N EN+RYL TKRD++GH L GLD+ E+ Sbjct 355 NNPAKRAGLEGYGLTVTGREGLPVRSNPENVRYLRTKRDRMGHLLDGLDEVTEA 408 >gi|213965612|ref|ZP_03393806.1| riboflavin biosynthesis protein ribBA [Corynebacterium amycolatum SK46] gi|213951771|gb|EEB63159.1| riboflavin biosynthesis protein ribBA [Corynebacterium amycolatum SK46] Length=420 Score = 573 bits (1476), Expect = 3e-161, Method: Compositional matrix adjust. Identities = 281/413 (69%), Positives = 335/413 (82%), Gaps = 3/413 (0%) Query 1 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVP 60 M + DSVERA+ADI AGKAV+V+DDEDRENEGD+IFAAEKATPE+VAFMVRY+SGY+C P Sbjct 1 MIKFDSVERAIADITAGKAVVVVDDEDRENEGDIIFAAEKATPELVAFMVRYSSGYICAP 60 Query 61 LDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVAD 120 L C+RL L PM + N+D GTAYTVTVDA G TGISA+DRA T+R LADPTS Sbjct 61 LTAEDCERLNLPPMVSENEDARGTAYTVTVDANTGT-TGISATDRANTIRTLADPTSSPH 119 Query 121 DFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDE 180 DFTRPGHVVPLRA++GGVL R GHTEAAVDLAR+AGL+PAG +CE+VS++D MA ++E Sbjct 120 DFTRPGHVVPLRAREGGVLVRAGHTEAAVDLARLAGLRPAGMLCEVVSEEDPTGMARSEE 179 Query 181 LRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVA 240 LR F D+H LALI+I LIE+RR +E IERV E ++PT +GEFRA+GY S+ + VEHVA Sbjct 180 LRRFCDKHDLALISIEQLIEYRRHNEHLIERVVETKLPTDYGEFRAVGYRSLIDGVEHVA 239 Query 241 LVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300 LV G+++ + DG DVLVRVHSECLTGD GSRRCDCG QL ++ MV GRGV+LYMR Sbjct 240 LVVGDVS--SNDGQDVLVRVHSECLTGDALGSRRCDCGQQLHNSMRMVHEAGRGVILYMR 297 Query 301 GHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLT 360 GHEGRGIGLM KLQAY LQD GADTVDANL LGLP+DAR+YG GAQIL DLGV SM LLT Sbjct 298 GHEGRGIGLMPKLQAYHLQDEGADTVDANLALGLPSDAREYGTGAQILQDLGVTSMALLT 357 Query 361 NNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHE 413 NNP KR GL GYGL + RVP+PV N +N++YL+TKR+++GH+L LD++ E Sbjct 358 NNPTKRAGLGGYGLEMSRRVPVPVEVNEDNLKYLLTKRERMGHELPWLDEYME 410 >gi|312195563|ref|YP_004015624.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Frankia sp. EuI1c] gi|311226899|gb|ADP79754.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Frankia sp. EuI1c] Length=514 Score = 571 bits (1471), Expect = 9e-161, Method: Compositional matrix adjust. Identities = 287/406 (71%), Positives = 333/406 (83%), Gaps = 6/406 (1%) Query 6 SVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAI 65 +VE AVA I AG+AV+V+DD DRENEGDLIFAAE ATPE+VAFMVR+TSG +C PL Sbjct 21 TVEDAVAAIRAGRAVVVVDDADRENEGDLIFAAEMATPELVAFMVRHTSGVICAPLTEQE 80 Query 66 CDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRP 125 DRL L M N ++ GTA+TV+VDAR G+ TGISA+DRA T+RLLA +V+ D +RP Sbjct 81 TDRLDLGQMVPTNTERMGTAFTVSVDAREGVSTGISAADRAHTLRLLAGAATVSTDLSRP 140 Query 126 GHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFA 185 GH+ PLRA++GGVLRRPGHTEAAVDLAR+AGL+PAGAICEIV+ D+G+MA +L VFA Sbjct 141 GHIFPLRAREGGVLRRPGHTEAAVDLARLAGLRPAGAICEIVN--DDGTMARLPQLVVFA 198 Query 186 DEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGE 245 EHGL LI+IADL+ +RR+ E + RVAEA +PT++G FRAIGY + VEHVAL+RGE Sbjct 199 REHGLVLISIADLVAYRRRTEMQVVRVAEASLPTKYGAFRAIGYRGTLDGVEHVALIRGE 258 Query 246 IAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGR 305 I DG +VLVRVHSECLTGDVFGS RCDCG QLDAAL MVA EGRGVVLYMRGHEGR Sbjct 259 IG----DGAEVLVRVHSECLTGDVFGSLRCDCGAQLDAALRMVAAEGRGVVLYMRGHEGR 314 Query 306 GIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAK 365 GIGLMHKL AYQLQDAG DTVDANL LGLPADARDYG+GAQ+LVDLGVR MRLLTNNPAK Sbjct 315 GIGLMHKLAAYQLQDAGHDTVDANLALGLPADARDYGVGAQVLVDLGVRGMRLLTNNPAK 374 Query 366 RVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDF 411 R GL+GYGL I+ERVPLPV EN+RYL TKRD++GHD+ GL + Sbjct 375 RAGLEGYGLSIVERVPLPVAHTPENLRYLTTKRDRMGHDIPGLPEL 420 Lambda K H 0.321 0.139 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 865206343656 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40