BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1427c Length=535 Score E Sequences producing significant alignments: (Bits) Value gi|15608565|ref|NP_215943.1| acyl-CoA synthetase [Mycobacterium ... 1083 0.0 gi|289447024|ref|ZP_06436768.1| long-chain fatty-acid-CoA ligase... 1080 0.0 gi|340626441|ref|YP_004744893.1| putative long-chain-fatty-acid-... 1079 0.0 gi|339298042|gb|AEJ50152.1| acyl-CoA synthetase [Mycobacterium t... 1065 0.0 gi|289442872|ref|ZP_06432616.1| long-chain fatty-acid-CoA ligase... 1017 0.0 gi|240171797|ref|ZP_04750456.1| acyl-CoA synthetase [Mycobacteri... 929 0.0 gi|254818395|ref|ZP_05223396.1| acyl-CoA synthetase [Mycobacteri... 903 0.0 gi|296170705|ref|ZP_06852280.1| acyl-CoA synthetase [Mycobacteri... 887 0.0 gi|183982246|ref|YP_001850537.1| long-chain-fatty-acid--CoA liga... 877 0.0 gi|342858723|ref|ZP_08715378.1| acyl-CoA synthetase [Mycobacteri... 875 0.0 gi|254775791|ref|ZP_05217307.1| acyl-CoA synthetase [Mycobacteri... 875 0.0 gi|41407257|ref|NP_960093.1| acyl-CoA synthetase [Mycobacterium ... 874 0.0 gi|118470076|ref|YP_884719.1| acyl-CoA synthetase [Mycobacterium... 829 0.0 gi|145221039|ref|YP_001131717.1| acyl-CoA synthetase [Mycobacter... 819 0.0 gi|315441989|ref|YP_004074868.1| acyl-CoA synthetase (AMP-formin... 816 0.0 gi|126436699|ref|YP_001072390.1| acyl-CoA synthetase [Mycobacter... 812 0.0 gi|120401258|ref|YP_951087.1| acyl-CoA synthetase [Mycobacterium... 810 0.0 gi|108800723|ref|YP_640920.1| acyl-CoA synthetase [Mycobacterium... 792 0.0 gi|126436346|ref|YP_001072037.1| acyl-CoA synthetase [Mycobacter... 791 0.0 gi|120405179|ref|YP_955008.1| acyl-CoA synthetase [Mycobacterium... 778 0.0 gi|315443470|ref|YP_004076349.1| acyl-CoA synthetase (AMP-formin... 776 0.0 gi|145223014|ref|YP_001133692.1| acyl-CoA synthetase [Mycobacter... 773 0.0 gi|118462880|ref|YP_882531.1| acyl-CoA synthetase [Mycobacterium... 749 0.0 gi|333988828|ref|YP_004521442.1| long-chain-fatty-acid-CoA ligas... 695 0.0 gi|289569444|ref|ZP_06449671.1| long-chain fatty-acid-CoA ligase... 636 3e-180 gi|343927858|ref|ZP_08767326.1| putative fatty-acid--CoA ligase ... 585 6e-165 gi|262203717|ref|YP_003274925.1| AMP-dependent synthetase and li... 549 5e-154 gi|284045146|ref|YP_003395486.1| AMP-dependent synthetase and li... 494 1e-137 gi|333920077|ref|YP_004493658.1| AMP-dependent synthetase and li... 457 3e-126 gi|119716227|ref|YP_923192.1| AMP-dependent synthetase and ligas... 444 2e-122 gi|326330577|ref|ZP_08196884.1| substrate--CoA ligase [Nocardioi... 440 3e-121 gi|302529170|ref|ZP_07281512.1| O-succinylbenzoate-CoA ligase [S... 438 1e-120 gi|257055386|ref|YP_003133218.1| acyl-CoA synthetase [Saccharomo... 430 2e-118 gi|134097880|ref|YP_001103541.1| acyl-CoA synthase [Saccharopoly... 426 5e-117 gi|291007402|ref|ZP_06565375.1| acyl-CoA synthase [Saccharopolys... 426 5e-117 gi|300788812|ref|YP_003769103.1| fatty-acyl-CoA synthase [Amycol... 421 2e-115 gi|300785001|ref|YP_003765292.1| fatty-acyl-CoA synthase [Amycol... 418 1e-114 gi|121636183|ref|YP_976406.1| acyl-CoA synthetase [Mycobacterium... 416 6e-114 gi|300787810|ref|YP_003768101.1| fatty-acyl-CoA synthase [Amycol... 416 7e-114 gi|15607411|ref|NP_214784.1| acyl-CoA synthetase [Mycobacterium ... 415 1e-113 gi|289441647|ref|ZP_06431391.1| fatty-acid-CoA ligase fadD2 [Myc... 414 2e-113 gi|291300476|ref|YP_003511754.1| AMP-dependent synthetase and li... 414 2e-113 gi|298523738|ref|ZP_07011147.1| acyl-CoA synthetase [Mycobacteri... 414 2e-113 gi|302526241|ref|ZP_07278583.1| O-succinylbenzoate-CoA ligase [S... 413 4e-113 gi|297559035|ref|YP_003678009.1| AMP-dependent synthetase and li... 413 5e-113 gi|269124818|ref|YP_003298188.1| AMP-dependent synthetase and li... 412 1e-112 gi|284041810|ref|YP_003392150.1| AMP-dependent synthetase and li... 409 1e-111 gi|54025764|ref|YP_120006.1| acyl-CoA synthetase [Nocardia farci... 408 1e-111 gi|118473796|ref|YP_885010.1| acyl-CoA synthetase [Mycobacterium... 407 2e-111 gi|289569445|ref|ZP_06449672.1| long-chain fatty-acid-CoA ligase... 403 5e-110 >gi|15608565|ref|NP_215943.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv] gi|15840884|ref|NP_335921.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551] gi|31792621|ref|NP_855114.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=535 Score = 1083 bits (2800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/535 (100%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID Sbjct 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN Sbjct 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA Sbjct 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP Sbjct 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI Sbjct 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD Sbjct 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY Sbjct 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV Sbjct 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS Sbjct 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 >gi|289447024|ref|ZP_06436768.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis CPHL_A] gi|289419982|gb|EFD17183.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis CPHL_A] Length=535 Score = 1080 bits (2794), Expect = 0.0, Method: Compositional matrix adjust. Identities = 534/535 (99%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID Sbjct 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCR+HRGFVDALLAVNRIGAHILLLN Sbjct 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRDHRGFVDALLAVNRIGAHILLLN 120 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA Sbjct 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP Sbjct 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI Sbjct 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD Sbjct 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY Sbjct 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV Sbjct 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS Sbjct 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 >gi|340626441|ref|YP_004744893.1| putative long-chain-fatty-acid--CoA ligase [Mycobacterium canettii CIPT 140010059] gi|340004631|emb|CCC43775.1| putative long-chain-fatty-acid--CoA ligase FADD12 (fatty-acid-CoA synthetase) (fatty-acid-COA synthase) [Mycobacterium canettii CIPT 140010059] Length=535 Score = 1079 bits (2790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/535 (99%), Positives = 533/535 (99%), Gaps = 0/535 (0%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPD PGLID Sbjct 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDHPGLID 60 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN Sbjct 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA Sbjct 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP Sbjct 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI Sbjct 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD Sbjct 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY Sbjct 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV Sbjct 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRG TGKILRTELQSRVGS Sbjct 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGTTGKILRTELQSRVGS 535 >gi|339298042|gb|AEJ50152.1| acyl-CoA synthetase [Mycobacterium tuberculosis CCDC5180] Length=527 Score = 1065 bits (2755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 526/527 (99%), Positives = 527/527 (100%), Gaps = 0/527 (0%) Query 9 LIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWR 68 +IATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWR Sbjct 1 MIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWR 60 Query 69 QLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPAL 128 QLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPAL Sbjct 61 QLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPAL 120 Query 129 AEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAHAGRRPE 188 AEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAHAGRRPE Sbjct 121 AEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAHAGRRPE 180 Query 189 HTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFS 248 HTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFS Sbjct 181 HTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFS 240 Query 249 QLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRS 308 QLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRS Sbjct 241 QLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRS 300 Query 309 LRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEG 368 LRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEG Sbjct 301 LRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEG 360 Query 369 TEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLF 428 TEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLF Sbjct 361 TEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLF 420 Query 429 VVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSA 488 VVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSA Sbjct 421 VVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSA 480 Query 489 TPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 TPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS Sbjct 481 TPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 527 >gi|289442872|ref|ZP_06432616.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T46] gi|289415791|gb|EFD13031.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T46] Length=535 Score = 1017 bits (2629), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/535 (98%), Positives = 520/535 (98%), Gaps = 0/535 (0%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID Sbjct 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN Sbjct 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA Sbjct 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP Sbjct 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI Sbjct 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 RNR +RPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD Sbjct 301 RNRTTAGRCGSPPRRVLPLRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY Sbjct 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV Sbjct 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS Sbjct 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 >gi|240171797|ref|ZP_04750456.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=544 Score = 929 bits (2400), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/538 (84%), Positives = 490/538 (92%), Gaps = 6/538 (1%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 R+ +A GLI TM RAGLIAP+RPDRYL+I AAMRREGMGFTAGFAGAA+RCPDRPGLIDE Sbjct 4 RVNEALGLITTMGRAGLIAPMRPDRYLKIAAAMRREGMGFTAGFAGAAQRCPDRPGLIDE 63 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 LGTLTWRQLDER +ALAAALQ LPAGPP+VVGIMCRNHRGFV+AL+A NRIGAH LLLNT Sbjct 64 LGTLTWRQLDERSSALAAALQDLPAGPPKVVGIMCRNHRGFVEALIATNRIGAHTLLLNT 123 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181 SFAGPALA+VV+RE VDTV+YDEEF+ATVDRA A+KP+ATRIVAWTD H+LTVEKL+AA Sbjct 124 SFAGPALADVVSRENVDTVIYDEEFTATVDRAFADKPEATRIVAWTDNQHELTVEKLIAA 183 Query 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVA 239 H+G++P G+ GK+ILLTSGTTGTPKGA HSGG G+ TLKA+LDRTPWRAEE VIVA Sbjct 184 HSGKQPRRPGTKGKLILLTSGTTGTPKGATHSGGSGGVRTLKAVLDRTPWRAEEPIVIVA 243 Query 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299 PMFHAWGFSQLVLA+SLACTI+TRR+FD EATLDL+DRH ATGL VVPVMFDRIM+LPAE Sbjct 244 PMFHAWGFSQLVLAASLACTIITRRKFDAEATLDLVDRHQATGLAVVPVMFDRIMELPAE 303 Query 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359 +R RY GRSLRFAAASGSRMRPDVVIAFM+QFGDVIYNNYNATEAGMIATATPADLR AP Sbjct 304 VRRRYSGRSLRFAAASGSRMRPDVVIAFMNQFGDVIYNNYNATEAGMIATATPADLRAAP 363 Query 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419 DTAG+PAEGTEIRILD +F E+P GEVG+IYVRN+SQFDGYTSG KDFHAGFMSSGDVG Sbjct 364 DTAGKPAEGTEIRILDPEFNELPVGEVGSIYVRNESQFDGYTSGTTKDFHAGFMSSGDVG 423 Query 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479 YLD+NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLA HP+VAEAAVIGVDD+QYGQRLAAF Sbjct 424 YLDQNGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPEVAEAAVIGVDDEQYGQRLAAF 483 Query 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 VVL P A PE LKQHVRDNLANYKVPR+I VLDELPRG TGKILR ELQS+V Sbjct 484 VVLAPDAHLDRGAAPEALKQHVRDNLANYKVPREITVLDELPRGSTGKILRAELQSKV 541 >gi|254818395|ref|ZP_05223396.1| acyl-CoA synthetase [Mycobacterium intracellulare ATCC 13950] Length=535 Score = 903 bits (2334), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/534 (82%), Positives = 481/534 (91%), Gaps = 2/534 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + + GLI TMRRAGLIAP+RPDRY+RI AAMRREGMG T+GFA AA+RCPDRPGLIDE Sbjct 1 MSETLGLIGTMRRAGLIAPMRPDRYVRIAAAMRREGMGMTSGFASAAQRCPDRPGLIDER 60 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G+LTWR+LDER NALAAALQ LP+G PRV+GIMCRNHRGFV+AL+A +RIG+ ILLLNTS Sbjct 61 GSLTWRELDERCNALAAALQGLPSGQPRVIGIMCRNHRGFVEALVAADRIGSDILLLNTS 120 Query 123 FAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAH 182 FAGPALA+VVTREGVD V+YDEEF+ TVDRALA P ATRIVAWTD +H+ TVE L+AA Sbjct 121 FAGPALADVVTREGVDAVIYDEEFTETVDRALAGTPDATRIVAWTDAEHERTVEGLIAAR 180 Query 183 AGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAP 240 AG +P+ TG GK+ILLTSGTTGTPKGA+ SGG GIGTLKAILDRTPWRAEE VIVAP Sbjct 181 AGAQPQRTGRKGKMILLTSGTTGTPKGAKQSGGNAGIGTLKAILDRTPWRAEEPIVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQL+LA+S AC ++TRR+FDPEATLDLIDRH ATGLVVVPVMFDRIMDLPAE+ Sbjct 241 MFHAWGFSQLLLAASFACPVITRRKFDPEATLDLIDRHKATGLVVVPVMFDRIMDLPAEV 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 R RY GRSLRFAAASGSRMRPDVV AFMD+FGDVIYNNYNATEAGMIATATPADLR APD Sbjct 301 RRRYSGRSLRFAAASGSRMRPDVVTAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPA GTEIRILD +F E+P GEVG+IYVRN++QFDGYTSG+ KDFHAGFMSSGDVGY Sbjct 361 TAGRPAGGTEIRILDPEFNELPAGEVGSIYVRNNTQFDGYTSGSTKDFHAGFMSSGDVGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LD GRLFVVGRDDEMIVSGGEN+YPIEVEK LA HPDVAEAAVIGVDD+QYGQRLAAFV Sbjct 421 LDSAGRLFVVGRDDEMIVSGGENVYPIEVEKALAAHPDVAEAAVIGVDDEQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVG 534 VL+PG ATP+ LKQHVRDNLANYKVPR+IAVLDELPR TGKILR EL++RVG Sbjct 481 VLEPGAGATPDALKQHVRDNLANYKVPREIAVLDELPRSSTGKILRAELRARVG 534 >gi|296170705|ref|ZP_06852280.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894694|gb|EFG74428.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=543 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/534 (81%), Positives = 474/534 (89%), Gaps = 3/534 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + A G++ T+RRAG+IAP+RPDRYL++ AAMRREGMG T GFA AA+RCPDRPGLIDEL Sbjct 8 VNDALGVVTTLRRAGMIAPMRPDRYLKMAAAMRREGMGMTVGFASAAQRCPDRPGLIDEL 67 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 GTLTWRQLDER NALAAALQ LP+G P+VVGIMCRNHRGFV+A++A NRIG+ ++LLNTS Sbjct 68 GTLTWRQLDERINALAAALQGLPSGQPKVVGIMCRNHRGFVEAVVATNRIGSDVVLLNTS 127 Query 123 FAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAW-TDEDHDLTVEKLVAA 181 FAGPALAEVV REGVD V+YDEEF+ TVDRALA+KP ATRIVAW + E TVEKL+ Sbjct 128 FAGPALAEVVNREGVDAVIYDEEFTETVDRALADKPDATRIVAWHSGERAGPTVEKLITD 187 Query 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVA 239 H G+RPE TG G++ILLTSGTTGTPKGA +GG GIGTLKAILDRTPWRAEE V+VA Sbjct 188 HPGQRPERTGRKGRMILLTSGTTGTPKGANQTGGNAGIGTLKAILDRTPWRAEETVVVVA 247 Query 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299 PMFHAWGFSQL+ A+S+ACT+VTRR+FDPEATLDLIDRH ATGL VVPVMFDRIM+LP E Sbjct 248 PMFHAWGFSQLIFAASMACTVVTRRKFDPEATLDLIDRHRATGLAVVPVMFDRIMELPPE 307 Query 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359 +R RY +SLRFAAASGSRMRPDVV AFMD+FGDVIYNNYNATEAGMIATATP DLR AP Sbjct 308 VRKRYSCKSLRFAAASGSRMRPDVVTAFMDEFGDVIYNNYNATEAGMIATATPEDLRAAP 367 Query 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419 DTAGRPA GTEIRILD FTE+PTGEVGTIYVRND+QF+GYTSG KDFHAGFMSSGDVG Sbjct 368 DTAGRPAGGTEIRILDSDFTELPTGEVGTIYVRNDTQFEGYTSGTTKDFHAGFMSSGDVG 427 Query 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479 YLDE GRLFVVGRDDEMIVSGGEN+YPIEVEKTLA HPDVAEAAVIGVDD+QYGQRLAAF Sbjct 428 YLDEAGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPDVAEAAVIGVDDEQYGQRLAAF 487 Query 480 VVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 VVL PG AT +TLKQHVR+NLA+YKVPR+I VLDELPRG TGKI R ELQSRV Sbjct 488 VVLNPGSGATVDTLKQHVRENLASYKVPREITVLDELPRGSTGKIQRNELQSRV 541 >gi|183982246|ref|YP_001850537.1| long-chain-fatty-acid--CoA ligase FadD12 [Mycobacterium marinum M] gi|183175572|gb|ACC40682.1| long-chain-fatty-acid--CoA ligase FadD12 [Mycobacterium marinum M] Length=544 Score = 877 bits (2267), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/538 (84%), Positives = 491/538 (92%), Gaps = 6/538 (1%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 RI Q GLI T+ R+GLIAP+RPDRYL+I AAMRREGMGFTAGFA AA+RCPDRPGL+DE Sbjct 4 RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMGFTAGFAAAAQRCPDRPGLVDE 63 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 LGTLTWRQLDER NALAAALQALPAG P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT Sbjct 64 LGTLTWRQLDERSNALAAALQALPAGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181 +FAGPALA+VV REGVDTV+YDEEF+ATVDRA +PQATRIVAW+D HDLTVE+LV A Sbjct 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183 Query 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVA 239 H G +PE TG G++ILLTSGTTGTPKGA+HSGG GIGTLKAILDRTPWRAE+ VIVA Sbjct 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHSGGSGGIGTLKAILDRTPWRAEQPIVIVA 243 Query 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299 PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP + Sbjct 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303 Query 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359 + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP Sbjct 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363 Query 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419 DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG KDFHAGFMSSGDVG Sbjct 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423 Query 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479 YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF Sbjct 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483 Query 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 VVL+P +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V Sbjct 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541 >gi|342858723|ref|ZP_08715378.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035] gi|342134427|gb|EGT87607.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035] Length=543 Score = 875 bits (2262), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/537 (79%), Positives = 473/537 (89%), Gaps = 6/537 (1%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + + GL+ T+ RAG+IAP+RPDRYL++ AAMRREGMG T GFA AA+RCPDRPGLIDE Sbjct 5 LSETLGLVTTLSRAGMIAPMRPDRYLKMAAAMRREGMGMTVGFASAAQRCPDRPGLIDER 64 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 GTLTWR+LDER NA AALQ LPAG P+VVGIMCRNHRGFV+A++AVNRIG+ ++LLNTS Sbjct 65 GTLTWRELDERINAFGAALQQLPAGQPKVVGIMCRNHRGFVEAVVAVNRIGSDVVLLNTS 124 Query 123 FAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAH 182 FAGPALAEVV REGVD VVYDEEF+ TV+RALA++P A RIVAWTD HDLTVE L+A H Sbjct 125 FAGPALAEVVNREGVDAVVYDEEFTPTVERALADRPDADRIVAWTDSHHDLTVEGLIAEH 184 Query 183 AGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAP 240 AG++P +G G++ILLTSGTTGTPKGA +GG GIGTLKAILDRTPWRAEE VIVAP Sbjct 185 AGQQPRRSGRKGRMILLTSGTTGTPKGANQTGGNAGIGTLKAILDRTPWRAEENIVIVAP 244 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQL+ A+S+ACT++TRR+FDPEATLDLIDRH ATGL VVPVMFDRIM+LP ++ Sbjct 245 MFHAWGFSQLIFAASMACTVITRRKFDPEATLDLIDRHRATGLAVVPVMFDRIMELPPDV 304 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 R RY RSLRFAAASGSRMRPDVVIAFMD FGDVIYNNYNATEAGMIATATP DLR APD Sbjct 305 RRRYSCRSLRFAAASGSRMRPDVVIAFMDAFGDVIYNNYNATEAGMIATATPQDLRAAPD 364 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPA GTEIRILD F E+PTGEVG+IYVRN++QFDGYTSG+ KDFHAGFMSSGD+GY Sbjct 365 TAGRPAGGTEIRILDPDFNELPTGEVGSIYVRNNTQFDGYTSGSTKDFHAGFMSSGDLGY 424 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LDE GRLFVVGRDDEMIVSGGEN+YPIEVEK LA HPDVAEA+VIGVDD+QYGQRLAAFV Sbjct 425 LDEAGRLFVVGRDDEMIVSGGENVYPIEVEKILAAHPDVAEASVIGVDDEQYGQRLAAFV 484 Query 481 VLKPGVS----ATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 VL+PG + A PE LKQHVR+NLANYK+PR+I VLDELPR TGKILR ELQ+RV Sbjct 485 VLEPGAALDAGAAPEALKQHVRENLANYKIPREITVLDELPRSSTGKILRAELQARV 541 >gi|254775791|ref|ZP_05217307.1| acyl-CoA synthetase [Mycobacterium avium subsp. avium ATCC 25291] Length=535 Score = 875 bits (2260), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/534 (81%), Positives = 482/534 (91%), Gaps = 2/534 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 +R+ GLIATMRRA L+AP+RPDRYLRI AAMRREGMG T+GFA AA+RCPDRPGL+DE Sbjct 1 MRETLGLIATMRRARLLAPMRPDRYLRIAAAMRREGMGMTSGFAAAAQRCPDRPGLVDER 60 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G+LTWRQLDER +ALAAALQALP+G P V+GIMCRNHRGFV+AL+A +RIGA I+LLNTS Sbjct 61 GSLTWRQLDERCDALAAALQALPSGAPAVIGIMCRNHRGFVEALVAADRIGADIVLLNTS 120 Query 123 FAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAH 182 FAGPALA+V+TREGVD V+YDEEF+ATVDRALA +P A RIVAWTD +H TV+KL+A+ Sbjct 121 FAGPALADVITREGVDAVIYDEEFTATVDRALAGRPDAIRIVAWTDTEHQHTVDKLIASK 180 Query 183 AGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAP 240 AG +P TG GK+ILLTSGTTGTPKGA+ SGG GIGTLKAILDRTPWRAEE VIVAP Sbjct 181 AGAQPIRTGRKGKMILLTSGTTGTPKGAKQSGGNAGIGTLKAILDRTPWRAEEPVVIVAP 240 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQL+LA+S AC ++TRR+FDPEATLDLIDRH ATGLVVVPVMFDRIMDLPA + Sbjct 241 MFHAWGFSQLLLAASFACPVITRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMDLPAGV 300 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 R RY+ RSLRFAAASGSRMRPDVV+AFMD+FGDVIYNNYNATEAGMIATATPADLR APD Sbjct 301 RRRYECRSLRFAAASGSRMRPDVVVAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPD 360 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPA GTEIRILD +F E+P GEVGTIYVRN++QFDGYTSG++KDFH GFMSSGD+GY Sbjct 361 TAGRPAGGTEIRILDPEFNELPAGEVGTIYVRNNTQFDGYTSGSSKDFHEGFMSSGDLGY 420 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LD GRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHPDVAEAAVIGVDD+QYGQRLAAFV Sbjct 421 LDSAGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPDVAEAAVIGVDDEQYGQRLAAFV 480 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVG 534 VL P ATPE LKQHVRDNLANYKVPR+I+VLDELPR TGKILR +L++RVG Sbjct 481 VLAPEARATPEALKQHVRDNLANYKVPREISVLDELPRSSTGKILRADLRARVG 534 >gi|41407257|ref|NP_960093.1| acyl-CoA synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395609|gb|AAS03476.1| FadD12_1 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457986|gb|EGO36973.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium avium subsp. paratuberculosis S397] Length=539 Score = 874 bits (2257), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/534 (81%), Positives = 481/534 (91%), Gaps = 2/534 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 +R+ GLIATMRRA L+AP+RPDRYLRI AAMRREGMG T+GFA AA+RCPDRPGL+DE Sbjct 5 VRETLGLIATMRRARLLAPMRPDRYLRIAAAMRREGMGMTSGFAAAAQRCPDRPGLVDER 64 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G+LTWRQLDER +ALAAALQAL +G P V+GIMCRNHRGFV+AL+A +RIGA I+LLNTS Sbjct 65 GSLTWRQLDERCDALAAALQALQSGAPAVIGIMCRNHRGFVEALVAADRIGADIVLLNTS 124 Query 123 FAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAH 182 FAGPALA+V+TREGV+ V+YDEEF+ATVDRALA +P A RIVAWTD +H TV+KL+A+ Sbjct 125 FAGPALADVITREGVNAVIYDEEFTATVDRALAGRPDAIRIVAWTDTEHQHTVDKLIASK 184 Query 183 AGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAP 240 AG RP TG GK+ILLTSGTTGTPKGA+ SGG GIGTLKAILDRTPWRAEE VIVAP Sbjct 185 AGARPIRTGRKGKMILLTSGTTGTPKGAKQSGGNAGIGTLKAILDRTPWRAEEPVVIVAP 244 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHAWGFSQL+LA+S AC ++TRR+FDPEATLDLIDRH ATGLVVVPVMFDRIMDLPAE+ Sbjct 245 MFHAWGFSQLLLAASFACPVITRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMDLPAEV 304 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 R RY+ RSLRFAAASGSRMRPDVV+AFMD+FGDVIYNNYNATEAGMIATATPADLR APD Sbjct 305 RRRYECRSLRFAAASGSRMRPDVVVAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPD 364 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 TAGRPA GTEIRILD +F E+P GEVGTIYVRN++QFDGYTSG++KDFH GFMSSGD+GY Sbjct 365 TAGRPAGGTEIRILDPEFNELPAGEVGTIYVRNNTQFDGYTSGSSKDFHEGFMSSGDLGY 424 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 LD GRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHPDVAEAAVIGVDD+QYGQRLAAFV Sbjct 425 LDSAGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPDVAEAAVIGVDDEQYGQRLAAFV 484 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVG 534 VL P TPE LKQHVRDNLANYKVPR+I+VLDELPR TGKILR +L++RVG Sbjct 485 VLAPEARTTPEALKQHVRDNLANYKVPREISVLDELPRSSTGKILRADLRARVG 538 >gi|118470076|ref|YP_884719.1| acyl-CoA synthetase [Mycobacterium smegmatis str. MC2 155] gi|118171363|gb|ABK72259.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155] Length=543 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/528 (78%), Positives = 453/528 (86%), Gaps = 4/528 (0%) Query 8 GLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTW 67 G++ TMRRAGLIAPLRPD+YLRIVAAM RE M T+GFA AA+RCPDRPGL+DELGTLTW Sbjct 16 GMVTTMRRAGLIAPLRPDKYLRIVAAMARENMSVTSGFASAAQRCPDRPGLVDELGTLTW 75 Query 68 RQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPA 127 R++D++ +ALAA LQAL G PRV+GIM RNHRGFV +L+A NRIGA +LLLNTSF+GPA Sbjct 76 REIDQQADALAAGLQALSGGAPRVLGIMARNHRGFVLSLIAANRIGADVLLLNTSFSGPA 135 Query 128 LAEVVTREGVDTVVYDEEFSATVDRALAEKPQA-TRIVAWTDED-HDLTVEKLVAAHAGR 185 LAEVV+RE VD V+YDEEF+ TVDRALA P+A TRIVAWTD HD+TV L AGR Sbjct 136 LAEVVSREKVDAVIYDEEFTDTVDRALAGAPEAPTRIVAWTDTAAHDVTVAALTEKFAGR 195 Query 186 RPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAW 245 +P+ G KVILLTSGTTGTPKGA+HSGGG LKAILDRTPWRAEE VIVAPMFHAW Sbjct 196 QPQRGGQKSKVILLTSGTTGTPKGAKHSGGGPEILKAILDRTPWRAEEPVVIVAPMFHAW 255 Query 246 GFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYD 305 GFSQL A+S+ACTI+TRR+FDPEATL+L+DRH ATGL VVPVMFDRIM+LP ++ NRYD Sbjct 256 GFSQLAFAASMACTIITRRKFDPEATLELVDRHRATGLCVVPVMFDRIMELPEDVLNRYD 315 Query 306 GRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRP 365 GRSLRFAAASGSRMRPDVVIAFMD+FGDVIYNNYNATEAGMIATATPADLR APDTAGRP Sbjct 316 GRSLRFAAASGSRMRPDVVIAFMDRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRP 375 Query 366 AEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENG 425 AEGTEIRILD ++PTGEVGTIYVRN +QFDGYTSG KDFH GFM SGDVG LD+ G Sbjct 376 AEGTEIRILDGDLRDLPTGEVGTIYVRNSTQFDGYTSGTTKDFHEGFMCSGDVGRLDDAG 435 Query 426 RLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPG 485 RLFVVGRDDEMIVSGGEN+YPIEVEK L THP VAEAAVIGVDD+Q+GQRLAAFVVL Sbjct 436 RLFVVGRDDEMIVSGGENVYPIEVEKVLTTHPAVAEAAVIGVDDEQFGQRLAAFVVLSG- 494 Query 486 VSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 AT + LK HVRDNLANYKVPRDI +LDELPR TGKI R ELQ +V Sbjct 495 -DATVDDLKSHVRDNLANYKVPRDITILDELPRNSTGKIARRELQEKV 541 >gi|145221039|ref|YP_001131717.1| acyl-CoA synthetase [Mycobacterium gilvum PYR-GCK] gi|145213525|gb|ABP42929.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] Length=544 Score = 819 bits (2115), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/535 (75%), Positives = 461/535 (87%), Gaps = 4/535 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + A GLI+TM RAG+IAP+RPD+Y+RIV AM+RE M T+GFA AA+RCPDR GL+DEL Sbjct 7 VTNALGLISTMMRAGVIAPMRPDKYMRIVGAMQRENMAITSGFAAAAQRCPDRAGLVDEL 66 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G LTWRQ+D+R +ALAAALQALP G P V+G+M RNHRGFVD+L+A NRIGA +LLLNTS Sbjct 67 GILTWRQIDQRADALAAALQALPEGQPEVIGLMARNHRGFVDSLIAANRIGADVLLLNTS 126 Query 123 FAGPALAEVVTREG---VDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHD-LTVEKL 178 FAGPALAEV+ REG V+YDEEF+ TVDRA+A++P+ TRI+AWTD D D LTVE L Sbjct 127 FAGPALAEVLQREGEGRAVAVIYDEEFTETVDRAVADRPETTRILAWTDSDTDALTVEGL 186 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIV 238 +A H G+ P + +VILLTSGTTGTPKGA+HSGG G LK+ILDRTPWRAE+ VIV Sbjct 187 IAEHGGQEPVRSVEKARVILLTSGTTGTPKGAKHSGGDPGVLKSILDRTPWRAEQPVVIV 246 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 APMFHAWGFSQL A+S++CTI+TRR+FDPEATL+L+D+ ATGL VVPVMFDRIM+LP Sbjct 247 APMFHAWGFSQLAFAASMSCTIITRRKFDPEATLELVDKFRATGLCVVPVMFDRIMELPE 306 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 E+ ++Y GRSLRFAAASGSRMRPD+VI FMD+FGDVIYNNYNATEAGMIATATP DLR A Sbjct 307 EVLDKYSGRSLRFAAASGSRMRPDIVIKFMDRFGDVIYNNYNATEAGMIATATPRDLRAA 366 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 PDTAGRPAEGTEI+ILD +F EVPTGE G I+VRN +QFDGYTSG+ KDFH GFMSSGDV Sbjct 367 PDTAGRPAEGTEIKILDSEFNEVPTGETGGIWVRNSTQFDGYTSGSTKDFHDGFMSSGDV 426 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 GYLDE GRLFVVGRDDEMIVSGGEN+YPIEVEKTL +HPDVAEA V+GVDD+++GQRLAA Sbjct 427 GYLDEEGRLFVVGRDDEMIVSGGENVYPIEVEKTLTSHPDVAEATVLGVDDEKFGQRLAA 486 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 FVVL PG +ATPE LKQHVRDNLANYKVPR+I VLDELPR ITGKI R +L+ R+ Sbjct 487 FVVLNPGAAATPEALKQHVRDNLANYKVPREITVLDELPRSITGKISRKDLKDRL 541 >gi|315441989|ref|YP_004074868.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|315260292|gb|ADT97033.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=544 Score = 816 bits (2107), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/535 (75%), Positives = 460/535 (86%), Gaps = 4/535 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + A GLI+TM RAG+IAP+RPD+Y+RIV AM+RE M T+GFA AA+RCPDR GL+DEL Sbjct 7 VTNALGLISTMMRAGVIAPMRPDKYMRIVGAMQRENMAITSGFAAAAQRCPDRAGLVDEL 66 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G LTWRQ+D+R +ALAAALQALP G P V+G+M RNHRGFVD+L+A NRIGA +LLLNTS Sbjct 67 GILTWRQIDQRADALAAALQALPEGQPEVIGLMARNHRGFVDSLIAANRIGADVLLLNTS 126 Query 123 FAGPALAEVVTREG---VDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHD-LTVEKL 178 FAGPALAEV+ REG V+YDEEF+ TVDRA+A++P+ TRI+AWTD D D LTVE L Sbjct 127 FAGPALAEVLQREGEGRAVAVIYDEEFTETVDRAVADRPETTRILAWTDSDTDALTVEGL 186 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIV 238 +A H G+ P + +VILLTSGTTGTPKGA+HSGG G LK+ILDRTPWRAE+ VIV Sbjct 187 IAEHGGQEPVRSVEKARVILLTSGTTGTPKGAKHSGGDPGVLKSILDRTPWRAEQPVVIV 246 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 APMFHAWGFSQL A+S++CTI+TRR+F PEATL+L+D+ ATGL VVPVMFDRIM+LP Sbjct 247 APMFHAWGFSQLAFAASMSCTIITRRKFHPEATLELVDKFRATGLCVVPVMFDRIMELPE 306 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 E+ ++Y GRSLRFAAASGSRMRPD+VI FMD+FGDVIYNNYNATEAGMIATATP DLR A Sbjct 307 EVLDKYSGRSLRFAAASGSRMRPDIVIKFMDRFGDVIYNNYNATEAGMIATATPRDLRAA 366 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 PDTAGRPAEGTEI+ILD +F EVPTGE G I+VRN +QFDGYTSG+ KDFH GFMSSGDV Sbjct 367 PDTAGRPAEGTEIKILDSEFNEVPTGETGGIWVRNSTQFDGYTSGSTKDFHDGFMSSGDV 426 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 GYLDE GRLFVVGRDDEMIVSGGEN+YPIEVEKTL +HPDVAEA V+GVDD+++GQRLAA Sbjct 427 GYLDEEGRLFVVGRDDEMIVSGGENVYPIEVEKTLTSHPDVAEATVLGVDDEKFGQRLAA 486 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 FVVL PG +ATPE LKQHVRDNLANYKVPR+I VLDELPR ITGKI R +L+ R+ Sbjct 487 FVVLNPGAAATPEALKQHVRDNLANYKVPREITVLDELPRSITGKISRKDLKDRL 541 >gi|126436699|ref|YP_001072390.1| acyl-CoA synthetase [Mycobacterium sp. JLS] gi|126236499|gb|ABN99899.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=540 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/534 (75%), Positives = 451/534 (85%), Gaps = 2/534 (0%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 R+R+ G++ TM RA +IAPLRPDRYLR+ AA+RR GM T GFA AA+RCPDRPGLIDE Sbjct 4 RLRKTAGIVGTMYRARVIAPLRPDRYLRMGAAVRRAGMSVTTGFALAAQRCPDRPGLIDE 63 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 LGTLTWR+LD +ALAAALQ LP G P VVGIM RNHRGFV+AL+A NRIGA +LLLNT Sbjct 64 LGTLTWRELDSHSDALAAALQTLPGGQPEVVGIMARNHRGFVEALVAANRIGADVLLLNT 123 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDED--HDLTVEKLV 179 SFAGPALA+VV RE VD V+YDEEF+ +V +AL ++P+A +IVAWTD+ +TV L+ Sbjct 124 SFAGPALADVVAREQVDAVIYDEEFAPSVAQALKDRPKAAKIVAWTDDPDAQAVTVAGLI 183 Query 180 AAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVA 239 H G+RP + K+ILLTSGTTG+PKGARHSGGG LK+ILDRTPWRAEEVTVIVA Sbjct 184 DGHIGQRPLPSDRTSKLILLTSGTTGSPKGARHSGGGADALKSILDRTPWRAEEVTVIVA 243 Query 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299 PMFHAWGF QLV A+ +ACTIVTRR+FDPEATL L+D H ATGL +VPVMFDRI+DLP + Sbjct 244 PMFHAWGFGQLVFAAMMACTIVTRRKFDPEATLALVDEHRATGLCLVPVMFDRIVDLPED 303 Query 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359 + +RY GR+LRFAAASGSRMRPDVVI FMD+FGDVIYNNYNATEAGMIATATP DLR AP Sbjct 304 VLSRYSGRTLRFAAASGSRMRPDVVIKFMDRFGDVIYNNYNATEAGMIATATPEDLRAAP 363 Query 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419 DTAG+ AEGT+IRILD F E P GEVGTIYVRN SQFDGYTSGA K+FH G+MSSGDVG Sbjct 364 DTAGKAAEGTDIRILDSDFHEQPRGEVGTIYVRNSSQFDGYTSGANKNFHDGYMSSGDVG 423 Query 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479 YLDE GRLFVVGRDDEMIVSGGEN+YPIEVEK LATHP+V EAAVIGVDD+QYGQRLAAF Sbjct 424 YLDEAGRLFVVGRDDEMIVSGGENVYPIEVEKALATHPEVNEAAVIGVDDEQYGQRLAAF 483 Query 480 VVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 VVL+ G SATPE LK HVR+NLANYKVPR I VL ELPRG TGKI+R EL + + Sbjct 484 VVLRDGASATPEDLKAHVRENLANYKVPRSITVLGELPRGSTGKIVRRELHALI 537 >gi|120401258|ref|YP_951087.1| acyl-CoA synthetase [Mycobacterium vanbaalenii PYR-1] gi|119954076|gb|ABM11081.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=544 Score = 810 bits (2093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/535 (75%), Positives = 450/535 (85%), Gaps = 4/535 (0%) Query 3 IRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDEL 62 + + GL++TM RAG+IAP+RPD+YLRI AM+RE M T+GFA AA+RCPDR GLIDEL Sbjct 7 VTKTLGLLSTMVRAGVIAPMRPDKYLRIAGAMQRENMAITSGFAAAAQRCPDRAGLIDEL 66 Query 63 GTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTS 122 G LTWRQ+D+R +A AAALQALP G P V+ +M RNHRGFVDAL+A NRIGA +LLLNTS Sbjct 67 GILTWRQIDQRADAFAAALQALPGGQPEVIALMARNHRGFVDALIAANRIGADVLLLNTS 126 Query 123 FAGPALAEVVTREGVD---TVVYDEEFSATVDRALAEKPQATRIVAWTDEDHD-LTVEKL 178 FAGPALAEV+ REG VVYDEEF+ TVDRALA +P TRIVAWTD D LTVE + Sbjct 127 FAGPALAEVMEREGEGRSVAVVYDEEFTDTVDRALAGRPDTTRIVAWTDTPGDRLTVEGM 186 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIV 238 +A H G+ P +VILLTSGTTGTPKGA HSGG LKAILDRTPWRAE+ VIV Sbjct 187 IAEHGGQEPVRAPEKSRVILLTSGTTGTPKGASHSGGDPSVLKAILDRTPWRAEQPVVIV 246 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 APMFHAWGFSQL A+S++CTIVTRRRFDPEATL+L+D++ ATGL VVPVMFDRIMDLP Sbjct 247 APMFHAWGFSQLAFAASMSCTIVTRRRFDPEATLELVDKYRATGLCVVPVMFDRIMDLPD 306 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 E+ ++Y GRSLRFAAASGSRMRPDVVI FMD+FGDVIYNNYNATEAGMIATATP DLR A Sbjct 307 EVLDKYSGRSLRFAAASGSRMRPDVVIKFMDRFGDVIYNNYNATEAGMIATATPRDLRAA 366 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 PDTAGRPAEGTEIRILD F EVPTGEVG IYVRN +QFDGYT+G KDFH GFMSSGDV Sbjct 367 PDTAGRPAEGTEIRILDADFNEVPTGEVGGIYVRNSTQFDGYTTGKTKDFHEGFMSSGDV 426 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 GY DE GRLFVVGRDDEMIVSGGEN+YPIEVEKTLA HPDVAEA V+GVDD+++GQRL A Sbjct 427 GYFDEAGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPDVAEATVLGVDDEKFGQRLEA 486 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 FVVL +ATPETLKQHVRDNLANYKVPR+I +LDELPRG+TGKI R +LQ R+ Sbjct 487 FVVLTADAAATPETLKQHVRDNLANYKVPREITILDELPRGVTGKISRKDLQDRL 541 >gi|108800723|ref|YP_640920.1| acyl-CoA synthetase [Mycobacterium sp. MCS] gi|119869862|ref|YP_939814.1| acyl-CoA synthetase [Mycobacterium sp. KMS] gi|108771142|gb|ABG09864.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119695951|gb|ABL93024.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] Length=548 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/537 (73%), Positives = 443/537 (83%), Gaps = 5/537 (0%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 ++ + GL+ T+ R+ LIAP+RPDRYL++ AA+RR GM T GFA AA+RCPDRPGLIDE Sbjct 11 KVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDRPGLIDE 70 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 G LT+ +LD+ +ALA ALQ LP G P V IMCRNHRGF++ALLA NRIGA+ LLLNT Sbjct 71 RGMLTFAELDDASDALAVALQGLPGGTPGTVAIMCRNHRGFIEALLAANRIGANALLLNT 130 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDE---DHDLTVEKL 178 SFAGPALAEV REG D V+YDEEFS TV+RAL+ P A RI+AWTDE + TV+ L Sbjct 131 SFAGPALAEVAEREGADVVIYDEEFSETVERALSGLPDAVRIIAWTDEPGGGAETTVDAL 190 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTV 236 + AH G RP ++ILLTSGTTGTPKGA+ S G G G LKA+LDRTPWRAEE TV Sbjct 191 IEAHRGERPRPAERSSEIILLTSGTTGTPKGAKRSAGSGGAGDLKAVLDRTPWRAEETTV 250 Query 237 IVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDL 296 IVAPMFHAWGFSQL+ A LACTIVTRRRFDPEATL L+D H ATGL+VVPVMFDRIMDL Sbjct 251 IVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEHKATGLIVVPVMFDRIMDL 310 Query 297 PAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLR 356 P E+R RY GRSLRFAAASGSRMRPDVV AFMDQFGDVIYNNYNATEAGMIATATPADLR Sbjct 311 PDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLR 370 Query 357 TAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSG 416 APDTAG PA+GTEIRI D F E+P GE G+I+VR+ + FDGYTSG+ KDFH GFM+SG Sbjct 371 AAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFDGYTSGSTKDFHDGFMASG 430 Query 417 DVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRL 476 DVGYLDENGRLFVVGRDDEMIVSGGEN+YPIEVEKTLA HP VAEA V+GVDD++YGQRL Sbjct 431 DVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPGVAEAEVLGVDDEKYGQRL 490 Query 477 AAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 AAFVV G S TP+ LK+HVRDNLANYKVPRDI +LDELPRG TGK+LR EL++ + Sbjct 491 AAFVVPAAGASLTPDELKEHVRDNLANYKVPRDIVILDELPRGGTGKVLRNELRAHL 547 >gi|126436346|ref|YP_001072037.1| acyl-CoA synthetase [Mycobacterium sp. JLS] gi|126236146|gb|ABN99546.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=548 Score = 791 bits (2043), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/537 (73%), Positives = 443/537 (83%), Gaps = 5/537 (0%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 ++ + GL+ T+ R+ LIAP+RPDRYL++ AA+RR GM T GFA AA+RCPDRPGLIDE Sbjct 11 KVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDRPGLIDE 70 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 G LT+ +LD+ +ALA ALQ LP G P V IMCRNHRGF++ALLA NRIGA+ LLLNT Sbjct 71 RGMLTFAELDDASDALAVALQGLPGGTPGTVAIMCRNHRGFIEALLAANRIGANALLLNT 130 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDE---DHDLTVEKL 178 SFAGPALAEV REG D V+YDEEFS TV+RAL+ P A RI+AWTDE + TV+ L Sbjct 131 SFAGPALAEVAEREGADVVIYDEEFSETVERALSGLPDAVRIIAWTDEPGGGAETTVDAL 190 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTV 236 + AH G RP ++ILLTSGTTGTPKGA+ S G G G LKA+LDRTPWRAEE TV Sbjct 191 IEAHRGERPRPAERSSEIILLTSGTTGTPKGAKRSAGSGGAGDLKAVLDRTPWRAEETTV 250 Query 237 IVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDL 296 IVAPMFHAWGFSQL+ A LACTIVTRRRFDPEATL L+D H ATGL+VVPVMFDRIMDL Sbjct 251 IVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEHKATGLIVVPVMFDRIMDL 310 Query 297 PAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLR 356 P E+R RY GRSLRFAAASGSRMRPDVV AFMDQFGDVIYNNYNATEAGMIATATPADLR Sbjct 311 PDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLR 370 Query 357 TAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSG 416 APDTAG PA+GTEIRI D F E+P GE G+I+VR+ + FDGYTSG+ KDFH GFM+SG Sbjct 371 AAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFDGYTSGSTKDFHDGFMASG 430 Query 417 DVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRL 476 DVGYLDENGRLFVVGRDDEMIVSGGEN+YPIEVEKTLA HP VAEA V+GVDD++YGQRL Sbjct 431 DVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPGVAEAEVLGVDDEKYGQRL 490 Query 477 AAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 AAFVV G + TP+ LK+HVRDNLANYKVPRDI +LDELPRG TGK+LR EL++ + Sbjct 491 AAFVVPAAGAALTPDELKEHVRDNLANYKVPRDIVILDELPRGGTGKVLRNELRAHL 547 >gi|120405179|ref|YP_955008.1| acyl-CoA synthetase [Mycobacterium vanbaalenii PYR-1] gi|119957997|gb|ABM15002.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=530 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/529 (74%), Positives = 436/529 (83%), Gaps = 6/529 (1%) Query 7 FGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLT 66 GL+AT+ RA LIAP+RPDRYLR+ AMRR G+ T GFA AA+RCPD PG+IDELGTLT Sbjct 5 LGLLATLWRARLIAPMRPDRYLRMGLAMRRAGLTATVGFAAAAQRCPDLPGIIDELGTLT 64 Query 67 WRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGP 126 W+QLD+R +ALAAALQ PR V +MCRNHRGFV+AL+ NRIGA +LLLNTSFAGP Sbjct 65 WKQLDDRCDALAAALQK---HTPRTVAVMCRNHRGFVEALVGANRIGADVLLLNTSFAGP 121 Query 127 ALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTD-EDHDLTVEKLVAAHAGR 185 A+AEV+ REG D V+YD+EF+ATVDRAL + P TRI+AWTD +D T+E L+ AH G+ Sbjct 122 AMAEVIEREGADIVIYDQEFTATVDRALRDVPGTTRILAWTDADDGSTTLEALIDAHLGQ 181 Query 186 RPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAPMFH 243 RPE +ILLTSGTTGTPKGA+ S G G LKA+LDRTPWRA E VI APMFH Sbjct 182 RPEPATRKSDIILLTSGTTGTPKGAKRSAGSGGASDLKAVLDRTPWRAGEPIVIAAPMFH 241 Query 244 AWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNR 303 AWGFSQL+ A+ LAC IVTRR+FDPEATL LIDRH ATGL VVPVMFDRIM+LPAE+RNR Sbjct 242 AWGFSQLLFAALLACPIVTRRKFDPEATLALIDRHRATGLAVVPVMFDRIMELPAEVRNR 301 Query 304 YDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAG 363 Y GRSLRFA ASGSRMRPDVV AFMDQFGDVIYNNYNATEAGMIATATPADLR APDTAG Sbjct 302 YSGRSLRFATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLRAAPDTAG 361 Query 364 RPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDE 423 R A+GTE+RILD + +VPTGEVG I+VR+ + FDGYTSG K FH GFM+SGD+GYLD Sbjct 362 RAADGTELRILDAEHRDVPTGEVGQIFVRSSTLFDGYTSGTTKAFHDGFMASGDMGYLDG 421 Query 424 NGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLK 483 GRLFVVGRDDEMIVSGGEN+YPIEVEKTL TH VAEAAV+GVDD+QYGQRLAAFVV Sbjct 422 AGRLFVVGRDDEMIVSGGENVYPIEVEKTLTTHAAVAEAAVLGVDDEQYGQRLAAFVVPA 481 Query 484 PGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSR 532 G S T E LKQHVR+NLANYKVPRDI ++ ELPRG TGKILR EL+ R Sbjct 482 AGASVTVEELKQHVRENLANYKVPRDITIMAELPRGSTGKILRNELRGR 530 >gi|315443470|ref|YP_004076349.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|315261773|gb|ADT98514.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=535 Score = 776 bits (2005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/529 (73%), Positives = 436/529 (83%), Gaps = 8/529 (1%) Query 7 FGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLT 66 FGL+AT+ RA LIAP+RPDRYLR+ AMRR G+ T GFA AA+RCPDRPG+IDELGTLT Sbjct 8 FGLLATLWRARLIAPMRPDRYLRMGLAMRRAGLTATVGFAAAAQRCPDRPGIIDELGTLT 67 Query 67 WRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGP 126 W+QLD+R +AL ALQ P+ V +MCRNHRGFV+AL+A NRIGA +LLLNTSFAGP Sbjct 68 WKQLDDRCDALGVALQK---EKPKTVAVMCRNHRGFVEALVAANRIGADVLLLNTSFAGP 124 Query 127 ALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL---TVEKLVAAHA 183 A+AEVV REG D V+YD+EF+ TVDRALA+ P A RIVAW D+ TVE L+ AH Sbjct 125 AMAEVVEREGADIVIYDQEFTETVDRALADTPGARRIVAWVDDPAQAGTATVEALIDAHL 184 Query 184 GRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAPM 241 G+RP+ VILLTSGTTG+PKGA+ S G G G LKA+LDRTPWRAEE VI APM Sbjct 185 GQRPQPATRKSDVILLTSGTTGSPKGAKRSAGSGGSGDLKAVLDRTPWRAEEPIVIAAPM 244 Query 242 FHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIR 301 FHAWGFSQL+ A+ LAC IVTRR+FDP ATL L+D++ ATGL VVPVMFDRIMDLP E+R Sbjct 245 FHAWGFSQLLFAALLACPIVTRRKFDPAATLALVDKYRATGLAVVPVMFDRIMDLPDEVR 304 Query 302 NRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDT 361 NRY GRSLRFA ASGSRMRPDVV AFMDQFGDVIYNNYNATEAGMIATATP DLR APDT Sbjct 305 NRYSGRSLRFATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPEDLRAAPDT 364 Query 362 AGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYL 421 AG+ A+GTE+RILD + E+PTGEVG I+VR+ + FDGYTSG+ KDFH GFM+SGD+GYL Sbjct 365 AGKAADGTELRILDAEHRELPTGEVGQIFVRSGTLFDGYTSGSTKDFHDGFMASGDLGYL 424 Query 422 DENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVV 481 D+ GRLFVVGRDDEMIVSGGEN+YPIEVEKTL +HP+VAEA V+GV+D +YGQRLAAFVV Sbjct 425 DDAGRLFVVGRDDEMIVSGGENVYPIEVEKTLMSHPEVAEATVLGVEDSEYGQRLAAFVV 484 Query 482 LKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 L G TPE LKQHVR NLANYKVPRDI +L ELPRG TGKILR EL+ Sbjct 485 LTDGSGLTPEDLKQHVRANLANYKVPRDITILPELPRGSTGKILRNELR 533 >gi|145223014|ref|YP_001133692.1| acyl-CoA synthetase [Mycobacterium gilvum PYR-GCK] gi|145215500|gb|ABP44904.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] Length=535 Score = 773 bits (1996), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/529 (73%), Positives = 435/529 (83%), Gaps = 8/529 (1%) Query 7 FGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLT 66 FGL+AT+ RA LIAP+RPDRYLR+ AMRR G+ T GFA AA+RCPDRPG+IDELGTLT Sbjct 8 FGLLATLWRARLIAPMRPDRYLRMGLAMRRAGLTATVGFAAAAQRCPDRPGIIDELGTLT 67 Query 67 WRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGP 126 W+QLD+R +AL ALQ P+ V +MCRNHRGFV+AL+A NRIGA +LLLNTSFAGP Sbjct 68 WKQLDDRCDALGVALQK---EKPKTVAVMCRNHRGFVEALVAANRIGADVLLLNTSFAGP 124 Query 127 ALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL---TVEKLVAAHA 183 A+AEVV REG D V+YD+EF+ TVDRALA+ A RIVAW D+ TVE L+ AH Sbjct 125 AMAEVVEREGADIVIYDQEFTETVDRALADTCGARRIVAWVDDPAQAGTATVEALIDAHL 184 Query 184 GRRPEHTGSHGKVILLTSGTTGTPKGARHSGG--GIGTLKAILDRTPWRAEEVTVIVAPM 241 G+RP+ VILLTSGTTG+PKGA+ S G G G LKA+LDRTPWRAEE VI APM Sbjct 185 GQRPQPATRKSDVILLTSGTTGSPKGAKRSAGSGGSGDLKAVLDRTPWRAEEPIVIAAPM 244 Query 242 FHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIR 301 FHAWGFSQL+ A+ LAC IVTRR+FDP ATL L+D++ ATGL VVPVMFDRIMDLP E+R Sbjct 245 FHAWGFSQLLFAALLACPIVTRRKFDPAATLALVDKYRATGLAVVPVMFDRIMDLPDEVR 304 Query 302 NRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDT 361 NRY GRSLRFA ASGSRMRPDVV AFMDQFGDVIYNNYNATEAGMIATATP DLR APDT Sbjct 305 NRYSGRSLRFATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPEDLRAAPDT 364 Query 362 AGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYL 421 AG+ A+GTE+RILD + E+PTGEVG I+VR+ + FDGYTSG+ KDFH GFM+SGD+GYL Sbjct 365 AGKAADGTELRILDAEHRELPTGEVGQIFVRSGTLFDGYTSGSTKDFHDGFMASGDLGYL 424 Query 422 DENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVV 481 D+ GRLFVVGRDDEMIVSGGEN+YPIEVEKTL +HP+VAEA V+GV+D +YGQRLAAFVV Sbjct 425 DDAGRLFVVGRDDEMIVSGGENVYPIEVEKTLMSHPEVAEATVLGVEDSEYGQRLAAFVV 484 Query 482 LKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 L G TPE LKQHVR NLANYKVPRDI +L ELPRG TGKILR EL+ Sbjct 485 LTDGSGLTPEDLKQHVRANLANYKVPRDITILPELPRGSTGKILRNELR 533 >gi|118462880|ref|YP_882531.1| acyl-CoA synthetase [Mycobacterium avium 104] gi|118164167|gb|ABK65064.1| acyl-CoA synthase [Mycobacterium avium 104] Length=447 Score = 749 bits (1935), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/446 (82%), Positives = 404/446 (91%), Gaps = 2/446 (0%) Query 91 VVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATV 150 ++GIMCRNHRGFV+A +A +RIGA I+LLNTSFAGPALA+V+TREGVD V+YDEEF+ATV Sbjct 1 MIGIMCRNHRGFVEAPVAADRIGADIVLLNTSFAGPALADVITREGVDAVIYDEEFTATV 60 Query 151 DRALAEKPQATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSHGKVILLTSGTTGTPKGA 210 DRALA +P A RIVAWTD +H TV+KL+A+ AG +P TG GK+ILLTSGTTGTPKGA Sbjct 61 DRALAGRPDAIRIVAWTDTEHQHTVDKLIASKAGAQPIRTGRKGKMILLTSGTTGTPKGA 120 Query 211 RHSGG--GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDP 268 + SGG GIGTLKAILDRTPWRAEE VIVAPMFHAWGFSQL+LA+S AC ++TRR+FDP Sbjct 121 KQSGGNAGIGTLKAILDRTPWRAEEPVVIVAPMFHAWGFSQLLLAASFACPVITRRKFDP 180 Query 269 EATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFM 328 EATLDLIDRH ATGLVVVPVMFDRIMDLPAE+R RY+ RSLRFAAASGSRMRPDVV+AFM Sbjct 181 EATLDLIDRHRATGLVVVPVMFDRIMDLPAEVRRRYECRSLRFAAASGSRMRPDVVVAFM 240 Query 329 DQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGT 388 D+FGDVIYNNYNATEAGMIATATPADLR APDTAGRPA GTEIRILD +F E+P GEVGT Sbjct 241 DEFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPAGGTEIRILDPEFNELPAGEVGT 300 Query 389 IYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIE 448 IYVRN++QFDGYTSG++KDFH GFMSSGD+GYLD GRLFVVGRDDEMIVSGGEN+YPIE Sbjct 301 IYVRNNTQFDGYTSGSSKDFHEGFMSSGDLGYLDSAGRLFVVGRDDEMIVSGGENVYPIE 360 Query 449 VEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPR 508 VEKTLATHPDVAEAAVIGVDD+QYGQRLAAFVVL P ATPE LKQHVRDNLANYKVPR Sbjct 361 VEKTLATHPDVAEAAVIGVDDEQYGQRLAAFVVLAPEARATPEALKQHVRDNLANYKVPR 420 Query 509 DIAVLDELPRGITGKILRTELQSRVG 534 +I+VLDELPR TGKILR +L++RVG Sbjct 421 EISVLDELPRSSTGKILRADLRARVG 446 >gi|333988828|ref|YP_004521442.1| long-chain-fatty-acid-CoA ligase [Mycobacterium sp. JDM601] gi|333484796|gb|AEF34188.1| long-chain-fatty-acid-CoA ligase FadD12 [Mycobacterium sp. JDM601] Length=545 Score = 695 bits (1793), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/538 (66%), Positives = 410/538 (77%), Gaps = 4/538 (0%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 R+ + ++ T RAGL+APLRPD+YLR+ AA REG T G A AA+RC DRP +IDE Sbjct 8 RLARIGSMLQTFARAGLLAPLRPDKYLRVAAAAAREGGTTTIGIAMAAQRCGDRPAIIDE 67 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 G+L++R+LD R +ALAA LQ LP P+ V +MCRNHRGF++AL A NRIGA +LLLNT Sbjct 68 RGSLSYRELDRRCDALAAGLQRLPGRTPQTVALMCRNHRGFIEALAAANRIGADVLLLNT 127 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDED-HDLTVEKLVA 180 SFAGPALAEVV REGVD + YDEEF+A VD A+ + + R+V+W D D LT + L+ Sbjct 128 SFAGPALAEVVAREGVDLIFYDEEFAAAVDLAVPAESRCVRVVSWADSDIPGLTADDLID 187 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGG---IGTLKAILDRTPWRAEEVTVI 237 A+ G+RP G +++LTSGTTGTPKGAR SG G + L AI D+ PW EE VI Sbjct 188 ANTGQRPAKPARTGSLVMLTSGTTGTPKGARRSGRGGGGVADLAAIFDKIPWHTEETVVI 247 Query 238 VAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLP 297 APMFHAWGFSQL LA ++ACTI TRR+FDPEATL L++ + A GL VVPVMFDRIM LP Sbjct 248 AAPMFHAWGFSQLALALTMACTIATRRKFDPEATLALVEYNDAAGLCVVPVMFDRIMALP 307 Query 298 AEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRT 357 ++R Y RSLRFA ASGSRMRPDVV AFMD FGDV+YNNYNATEAGMIA ATP DLR Sbjct 308 DDVRAEYPCRSLRFATASGSRMRPDVVTAFMDAFGDVVYNNYNATEAGMIALATPEDLRY 367 Query 358 APDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGD 417 +PDTAGRPA GTEIRILD F EV G G I+VRN SQF+GYT G +K FH GFM+SGD Sbjct 368 SPDTAGRPAPGTEIRILDPDFAEVADGITGQIFVRNSSQFEGYTGGDSKQFHDGFMASGD 427 Query 418 VGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLA 477 +GY D GRLFVVGRDDEMIVSGGEN+YPIE EK L +H VAEAAVIGVDD YGQRL Sbjct 428 LGYFDPTGRLFVVGRDDEMIVSGGENVYPIETEKALISHGAVAEAAVIGVDDADYGQRLV 487 Query 478 AFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS 535 AFVVL+PG SATP+ LKQHVRDNLA YKVPR I +L+ LPR TGK+LR ELQ+ G+ Sbjct 488 AFVVLEPGASATPDELKQHVRDNLAGYKVPRAITILEALPRNNTGKVLRRELQAMAGT 545 >gi|289569444|ref|ZP_06449671.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T17] gi|289543198|gb|EFD46846.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T17] Length=312 Score = 636 bits (1640), Expect = 3e-180, Method: Compositional matrix adjust. Identities = 311/312 (99%), Positives = 312/312 (100%), Gaps = 0/312 (0%) Query 224 LDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGL 283 +DRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGL Sbjct 1 MDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGL 60 Query 284 VVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATE 343 VVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATE Sbjct 61 VVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATE 120 Query 344 AGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSG 403 AGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSG Sbjct 121 AGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSG 180 Query 404 AAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAA 463 AAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAA Sbjct 181 AAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAA 240 Query 464 VIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGK 523 VIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGK Sbjct 241 VIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGK 300 Query 524 ILRTELQSRVGS 535 ILRTELQSRVGS Sbjct 301 ILRTELQSRVGS 312 >gi|343927858|ref|ZP_08767326.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] gi|343762499|dbj|GAA14252.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] Length=549 Score = 585 bits (1508), Expect = 6e-165, Method: Compositional matrix adjust. Identities = 298/534 (56%), Positives = 374/534 (71%), Gaps = 4/534 (0%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGF-TAGFAGAARRCPDRPGLID 60 R+ L+ T+ R+G + LR DRY+R+ +RR G +G AA R P L+D Sbjct 8 RVTTYTWLVRTLIRSGFLGSLRLDRYIRMGLNLRRHGGASPVSGIGLAAARAPKGLALVD 67 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 E G LTW +LD R +ALA L+ LP V I+CRNHRG ++AL A +R+GA +LLN Sbjct 68 EAGELTWGELDARCDALAVGLRELPGTSVNTVAILCRNHRGLIEALAATSRLGADAVLLN 127 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDED--HDLTVEKL 178 T FAGP LA+V+ REG D ++ D+EF A V A P RI AWT+ T++ L Sbjct 128 TGFAGPQLADVLEREGADVLIADDEFDAVVAPAAERLPNVRRIHAWTESGPVSADTIDSL 187 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGG-GIGTLKAILDRTPWRAEEVTVI 237 + A+ GRRP G+++LLTSGTTGTPKGAR G I +L A+LDR PWRA E TVI Sbjct 188 IDANLGRRPARPERAGRIVLLTSGTTGTPKGARRGGSTDIASLAAMLDRIPWRAGESTVI 247 Query 238 VAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLP 297 AP+FHAWGF Q+ +++++ CT++ RRRFDPEATLDL+ H ATGL VVPVM +RIMDLP Sbjct 248 AAPIFHAWGFGQVAISATMTCTMIMRRRFDPEATLDLVREHEATGLAVVPVMLERIMDLP 307 Query 298 AEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRT 357 EI + SLRFA ASGSRMR D +IAF+D+FGDV+YN+YNATEAG+I+TATP DLR Sbjct 308 DEILETHPMPSLRFATASGSRMRTDALIAFLDRFGDVVYNSYNATEAGLISTATPEDLRV 367 Query 358 APDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGD 417 APDTAGRP GT +RILD E+PTGE+G I V N+S FDGYT+ K F G M SGD Sbjct 368 APDTAGRPLTGTSVRILDDDDRELPTGEIGRIVVANNSGFDGYTTADTKAFSDGHMVSGD 427 Query 418 VGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLA 477 VG +DENGRLFVVGRDDEMIVSGGEN+YP+EVE+ + +V E VIGVDD+++GQRLA Sbjct 428 VGRIDENGRLFVVGRDDEMIVSGGENVYPLEVEQVIGALDEVHEVVVIGVDDEKFGQRLA 487 Query 478 AFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 A+VV P + ++QHVR+ LA +KVPRD+ LDELPR TGKIL+ +L S Sbjct 488 AYVVRAPQTLIGADQIRQHVREQLAGFKVPRDVHFLDELPRNATGKILKRDLLS 541 >gi|262203717|ref|YP_003274925.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] gi|262087064|gb|ACY23032.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] Length=550 Score = 549 bits (1414), Expect = 5e-154, Method: Compositional matrix adjust. Identities = 292/524 (56%), Positives = 366/524 (70%), Gaps = 3/524 (0%) Query 9 LIATMRRAGLIAPLRPDRYLRIVAAMRREGMGF-TAGFAGAARRCPDRPGLIDELGTLTW 67 LI T+ +G + LR DRY+R+ AMRR G +G AA R P L+D+ G LTW Sbjct 14 LIRTLVGSGFLGSLRLDRYVRMGLAMRRHGGASPVSGIGLAAARDPHGRALLDDAGHLTW 73 Query 68 RQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPA 127 R+LD+R +ALAAAL L V IMCRNHRG +++L A +R+G +LLNT FA P Sbjct 74 RELDDRCDALAAALADLGGHRVTTVAIMCRNHRGIIESLAATSRLGLDSVLLNTGFAAPQ 133 Query 128 LAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTD-EDHDLTVEKLVAAHAGRR 186 LA+V+ RE VD V+ D+EF + AL PQ + AW + TV+ L+ A+ GRR Sbjct 134 LADVLIREHVDLVIADDEFDGLIAHALGRNPQLRHVRAWVEGTATGDTVDGLIEANLGRR 193 Query 187 PEHTGSHGKVILLTSGTTGTPKGARHSGG-GIGTLKAILDRTPWRAEEVTVIVAPMFHAW 245 G+++LLTSGTTGTPKGAR G IG+L A+LDR PWRA E TVI AP+FHAW Sbjct 194 APVPERAGRIVLLTSGTTGTPKGARRGGSTDIGSLAAMLDRIPWRAGETTVIAAPIFHAW 253 Query 246 GFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYD 305 GF Q+ +++++ CT+V RRRFDP ATL+L+ H A GL VVPVM +RIMDLP ++ + + Sbjct 254 GFGQVAISATMTCTMVMRRRFDPVATLELVREHGAGGLAVVPVMLERIMDLPDDVLDAHQ 313 Query 306 GRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRP 365 SLRF ASGSRMR D ++ FMD+FGDV+YN+YNATEAG+I+TATPADLR APDTAGRP Sbjct 314 MPSLRFVTASGSRMRTDALLGFMDRFGDVVYNSYNATEAGLISTATPADLRLAPDTAGRP 373 Query 366 AEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENG 425 GT +R+LD EVPTGEVG I V ++S FDGYTS K F G M SGDVG +DE G Sbjct 374 LTGTSVRLLDDADREVPTGEVGRIVVASNSGFDGYTSSDTKAFADGHMVSGDVGRVDERG 433 Query 426 RLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPG 485 LFVVGRDDEMIVSGGEN+YP+EVE+ + HP V E AVIGVDD ++GQRLAA+VV P Sbjct 434 LLFVVGRDDEMIVSGGENVYPLEVEQVIGAHPAVREVAVIGVDDPKFGQRLAAYVVRAPQ 493 Query 486 VSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTEL 529 E L+ HVR+ LA +KVPRD+ +DELPR TGK+L+ +L Sbjct 494 TIVGAEALRDHVREQLAGFKVPRDVHFIDELPRNATGKVLKRQL 537 >gi|284045146|ref|YP_003395486.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] gi|283949367|gb|ADB52111.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] Length=532 Score = 494 bits (1273), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 264/529 (50%), Positives = 345/529 (66%), Gaps = 7/529 (1%) Query 5 QAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGT 64 QAF + T+ +GLI P RPDR ++ A++R G FA A R PD+P +IDELGT Sbjct 8 QAF-VAKTLVGSGLIGPTRPDRLAKVGLALKRWGTTSAGAFAVTAARKPDQPAIIDELGT 66 Query 65 LTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFA 124 L++ +L R NALA++ P + +MCRNHRGFVD +A +R+GA+I+ LNT+FA Sbjct 67 LSYGELHRRANALASSFANEGIRPGDAIAVMCRNHRGFVDVTVATSRLGANIIYLNTAFA 126 Query 125 GPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDH---DLTVEKLVAA 181 GP LAEV+ RE +VYDEEF+ V+ A + VAW D + D +E L+A Sbjct 127 GPQLAEVIERERAAAIVYDEEFANIVEPVRAGRKS---YVAWHDGESANGDRLIEDLIAE 183 Query 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPM 241 G+VI+LTSGTTG PKGAR S G+G A+L + P +A E T+I AP+ Sbjct 184 GDAAGVPPAAEPGRVIILTSGTTGAPKGARRSAAGLGAAAALLSKMPLKARETTMIAAPI 243 Query 242 FHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIR 301 FH WG + L LA TIV RRRFDPE TL I RH A+GLVVVPVM R+++LP ++ Sbjct 244 FHTWGLAHFTLGVPLASTIVLRRRFDPEGTLRAIARHRASGLVVVPVMLQRMLELPDDVF 303 Query 302 NRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDT 361 +YD SLR AASGS + + MD+FGDV+YN Y +TE ATPAD+R AP T Sbjct 304 AKYDTSSLRVIAASGSALPGPLSTRVMDRFGDVLYNTYGSTEVAWATIATPADMRAAPGT 363 Query 362 AGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYL 421 AGRP GT +R+LD+ EVP G+ G I+V N+ F+GYT G K+ G MSSGDVG+ Sbjct 364 AGRPPVGTRVRLLDEDGREVPAGQTGRIFVGNELPFEGYTGGGNKEIIDGLMSSGDVGHF 423 Query 422 DENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVV 481 D GRLFV GRDD+MI+SGGEN++P EVE LA H V E AVIG+ D+++GQRL A VV Sbjct 424 DSGGRLFVDGRDDDMIISGGENVFPSEVEDLLAGHGAVREVAVIGIADEEWGQRLKAVVV 483 Query 482 LKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 L P ++T + LK +VR NLA +KVPR++ ++ELPR TGK+L+ EL+ Sbjct 484 LNPEAASTEDELKAYVRANLAGFKVPREVVFVEELPRNATGKVLKRELR 532 >gi|333920077|ref|YP_004493658.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333482298|gb|AEF40858.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus DQS3-9A1] Length=692 Score = 457 bits (1175), Expect = 3e-126, Method: Compositional matrix adjust. Identities = 248/525 (48%), Positives = 319/525 (61%), Gaps = 12/525 (2%) Query 13 MRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDE 72 + R G++ P+RPD R+ A R G+ A A R P ++DE GT T+ ++DE Sbjct 169 LARRGIVRPMRPDTLFRLAWAARTWGLSLGTAVAAGAIRSGGAPLIVDEFGTQTYAEVDE 228 Query 73 RGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVV 132 R NA+A+ L VG++ RNHRGF++A AV ++GA +LLLNT F+GP L EV Sbjct 229 RSNAIASGLALHGVTESDTVGVLARNHRGFLEAATAVAKVGADVLLLNTEFSGPQLREVT 288 Query 133 TREGVDTVVYDEEFSATVDRALAEKP-QATRIVAWTDEDHDL-TVEKLVAAHAGRRPEHT 190 TRE V V+YD EF A + + P R+ + D D D ++ + GRRP Sbjct 289 TREAVSAVIYDTEFHAL----MGDSPMHMLRVFSDADPDGDAPSLASFAVEYHGRRPPVP 344 Query 191 GSHGKVILLTSGTTGTPKGARH---SGGGIGTLKA---ILDRTPWRAEEVTVIVAPMFHA 244 GK+ +LTSGTTGTPKGA + GG TL+A +L R P RA + AP FHA Sbjct 345 NRSGKLTILTSGTTGTPKGATRGAVAAGGTLTLEAPAALLGRIPLRAGMRIGLAAPAFHA 404 Query 245 WGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRY 304 WG + LV+A L ++V RRF E L IDR + +PVM RI+DLP ++R++Y Sbjct 405 WGLANLVMALGLGASVVMLRRFSAEEWLAEIDRSKCEAFIAIPVMLQRILDLPKDVRDKY 464 Query 305 DGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGR 364 D SL A SGS + D+ +MD FGD +YN Y +TE ATP DLRTAP TAGR Sbjct 465 DTSSLEVVAVSGSALAGDLATRWMDSFGDNLYNLYGSTEVANATIATPQDLRTAPGTAGR 524 Query 365 PAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDEN 424 P GT +R+ DQ EV GE G IYV N F+GYT G K+ G M++GD+G DE Sbjct 525 PTRGTTVRLFDQSGKEVRQGETGRIYVGNAHLFEGYTGGGDKERIGGLMATGDLGRFDEA 584 Query 425 GRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKP 484 GRLFVVGRDDEMIVSGGEN+YP EVE +A H VAEAA +GVDD ++GQRL AFVVL+ Sbjct 585 GRLFVVGRDDEMIVSGGENVYPREVEDVIARHASVAEAACVGVDDDKFGQRLRAFVVLRD 644 Query 485 GVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTEL 529 G + + + +K VR LA YKVPRDI LD LPR GKI++ +L Sbjct 645 GETLSADEVKDLVRAQLARYKVPRDIEFLDALPRNAAGKIVKRQL 689 >gi|119716227|ref|YP_923192.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614] gi|119536888|gb|ABL81505.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614] Length=541 Score = 444 bits (1142), Expect = 2e-122, Method: Compositional matrix adjust. Identities = 254/528 (49%), Positives = 321/528 (61%), Gaps = 13/528 (2%) Query 10 IATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQ 69 + + AG+I P P ++ A++ G G GF AA P R +IDELG+LT+ + Sbjct 20 LKVLGEAGVIRPRNPVALAKVAKALKDWGTGPAGGFTAAALLDPRRTAIIDELGSLTFAE 79 Query 70 LDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALA 129 L R NALA A L V +MCRNHRGFV+A +A ++GA IL LNT+FAGP L Sbjct 80 LQRRSNALARAFAELGVSEGDSVALMCRNHRGFVEASIAAAKLGADILYLNTAFAGPQLV 139 Query 130 EVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL-----TVEKLVAAHAG 184 EV+ RE VV+DEEF+ R LA+ T ++AWTD T+E L+A +G Sbjct 140 EVLEREQPALVVHDEEFT----RLLAKADVGTSVLAWTDSADSDDSADPTLESLIAGRSG 195 Query 185 RRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHA 244 E TG HG++++LTSGTTGTPKGA S GI ++L R P R T I AP+FH Sbjct 196 ADLEPTGRHGRIVILTSGTTGTPKGAPRSEAGIDAAVSLLSRMPLRYGWRTHIAAPLFHT 255 Query 245 WGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRY 304 WGF+ L LA L TIV RRRFDPEA L LVV+PVM R+M LP E RY Sbjct 256 WGFAHLALAMLLGSTIVLRRRFDPEACLRATQDERCDSLVVIPVMLQRMMALPEETLARY 315 Query 305 DGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGR 364 D ++ A+SGS + D+ +MD FGD +YN Y +TE + ATP DLR AP AG+ Sbjct 316 DLSRVQVVASSGSALPGDLATDWMDHFGDHLYNIYGSTEVAYASIATPLDLREAPSAAGK 375 Query 365 PAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDEN 424 P T ++ILD E+P GE G I+V N F+GYT G K+ G MS+GDVG D + Sbjct 376 PPYATIVKILDPDGRELPQGETGRIFVGNGLLFEGYTGGGHKEVVDGLMSTGDVGRFDTD 435 Query 425 GRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKP 484 GRL V GRDDEMIVSGGEN++P EVE L H V E A +GVDD +G+RL AFVV+ Sbjct 436 GRLHVEGRDDEMIVSGGENVFPKEVEDCLMRHDAVVEVAAVGVDDPDFGKRLRAFVVVS- 494 Query 485 GVSATPET-LKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 A PE LK V++NLA YKVPRD+ LDELPR TGK+L+ +L + Sbjct 495 --RAVPEQELKDWVKENLARYKVPRDVVFLDELPRNATGKVLKRDLDT 540 >gi|326330577|ref|ZP_08196884.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1] gi|325951652|gb|EGD43685.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1] Length=554 Score = 440 bits (1131), Expect = 3e-121, Method: Compositional matrix adjust. Identities = 243/522 (47%), Positives = 317/522 (61%), Gaps = 11/522 (2%) Query 16 AGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGN 75 +G++ P+ P R A+ R G G GF G A R P R LIDELG+LT+ +LD R N Sbjct 22 SGIVRPVNPLGLARTGLALARWGTGPAGGFIGLAHRYPRRTALIDELGSLTYAELDRRSN 81 Query 76 ALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTRE 135 A+A AL A G V IMCRNHRGFVDA LAV ++GA L LNT+FAGP L V+ R+ Sbjct 82 AIARALAARGVGEGDGVAIMCRNHRGFVDATLAVAKLGADALYLNTAFAGPQLVGVLERD 141 Query 136 GVDTVVYDEEFSATVDRALAEKPQATRIVAWTDE-DHDLTVEKLVAAHAGRRPEHTGSHG 194 +++DEEF+ L+ ATR+VAW D D T+E LV+ A R HG Sbjct 142 KPALIIHDEEFTGL----LSSATSATRLVAWVDSSDPGETLESLVSGDA-RPVAPPKRHG 196 Query 195 KVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLAS 254 ++++LTSGTTG PK A G+ A++ R P + I AP+FH WG + L+ A Sbjct 197 RIVILTSGTTGAPKSAPRQEAGVDAAIALMSRMPMKDGWRCFIAAPLFHTWGIAHLLFAE 256 Query 255 SLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRF--- 311 L T++ RRRFDPE L + A VV+PVM RI+ LP E YD + + F Sbjct 257 LLGTTMILRRRFDPEDALATLAETKADSFVVIPVMMQRILSLPEETLAAYDLQGIAFRLK 316 Query 312 -AAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTE 370 A+SGS + D+ + +MD+FGD +YN Y +TE + A P DLR AP +AG+ GT Sbjct 317 AVASSGSALPGDLALEWMDRFGDSLYNVYGSTEVSYASIADPVDLREAPTSAGKVPWGTR 376 Query 371 IRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVV 430 ++ILD VP GE G I+V N F+GYTSG K+ G M++GDVG +GRL+V Sbjct 377 MKILDGDGVPVPDGEAGRIFVGNGLLFEGYTSGGGKEVVDGLMATGDVGRFGPDGRLYVE 436 Query 431 GRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATP 490 GRDD+MIVSGGEN++P EVE L HP VA+AA +GVDD +G+RL FVVL PG Sbjct 437 GRDDDMIVSGGENVFPQEVEDCLIRHPLVADAACVGVDDADFGKRLRGFVVLAPGAEGDV 496 Query 491 E-TLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 + LK V++NLA +KVPR+I V D LPR TGK+LR EL + Sbjct 497 DAVLKDWVKENLARFKVPREIVVTDALPRNATGKVLRRELAT 538 >gi|302529170|ref|ZP_07281512.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4] gi|302438065|gb|EFL09881.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4] Length=541 Score = 438 bits (1127), Expect = 1e-120, Method: Compositional matrix adjust. Identities = 241/525 (46%), Positives = 320/525 (61%), Gaps = 8/525 (1%) Query 10 IATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQ 69 + MRRAGL+ R D LR + A+R+ G F AARR G++D+LG LT++Q Sbjct 21 VEVMRRAGLVPFPRLDEGLRSLVAIRKYGP-FAGANHIAARRDSTAVGIVDDLGPLTFKQ 79 Query 70 LDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALA 129 LD++ NALA A GP V+ +CR+HRG V + A ++GA +LL+NT FA P A Sbjct 80 LDDQSNALARAWSQRGLGPGSVIAALCRDHRGLVVTMAASGKLGARLLLMNTGFAKPQFA 139 Query 130 EVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDE--DHDLTVEKLVAAHAGRRP 187 +V REGV +VYD+EF+ +D A R +AW DE H++ V + A RP Sbjct 140 DVAKREGVTALVYDQEFTGLLD---AIDEDVDRYLAWVDEPGGHEIPVLAEIIASTDDRP 196 Query 188 -EHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWG 246 G +LLTSGTTGTPKGA LDR P RA E T + AP+FH G Sbjct 197 LPAPAKPGGFVLLTSGTTGTPKGAPRPHTSALASAQFLDRIPLRAGEATFMGAPLFHGTG 256 Query 247 FSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDG 306 SQ +L+ +L CT+V RR+FDPEATL + +H T LV+VP M RI+DLP E+R+RYD Sbjct 257 LSQFILSFALGCTVVMRRKFDPEATLKGVAQHRCTALVLVPTMLQRIVDLPKEVRDRYDT 316 Query 307 RSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPA 366 LR +GS + PD+ +QFGDV++N Y +TE + ATP D + AP T GR Sbjct 317 SCLRIIFVAGSALSPDLGNRANEQFGDVVHNLYGSTEVAVATVATPEDWKRAPGTVGRAP 376 Query 367 EGTEIRILDQQFTEVPTGEV-GTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENG 425 G + + D+ ++ V G ++V + F GYT G K+ G +SSGDVG+ DE G Sbjct 377 VGCRVALYDEHGGKITEPHVTGRVFVGSGLSFGGYTDGRNKEIIDGLLSSGDVGHFDEEG 436 Query 426 RLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPG 485 LF+ GRDDEMIVSGGEN++PIEVE L DV EAAVIGV+D +G+RL AFVV G Sbjct 437 LLFIDGRDDEMIVSGGENVFPIEVENLLVEREDVLEAAVIGVEDADFGERLKAFVVRAEG 496 Query 486 VSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 + + ++++V+ NLA YKVPRD+ LDELPR TGK+LRT+L Sbjct 497 STLDEDGVREYVKANLARYKVPRDVEFLDELPRNATGKVLRTKLS 541 >gi|257055386|ref|YP_003133218.1| acyl-CoA synthetase [Saccharomonospora viridis DSM 43017] gi|256585258|gb|ACU96391.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Saccharomonospora viridis DSM 43017] Length=539 Score = 430 bits (1106), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 242/533 (46%), Positives = 318/533 (60%), Gaps = 9/533 (1%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 R +A +A + RAGL R D +R + + RR G AARR P GL+DE Sbjct 12 RAVEAVRSLAVLYRAGLAPIPRLDEGIRSIISTRRYGP-LAGSVKIAARRDPHSVGLVDE 70 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 G+LT+ QLD R NALA A A P V ++CR+HRG V ALLA ++GA +LLLNT Sbjct 71 RGSLTYTQLDLRSNALARAWAARGVRPGTTVAVLCRDHRGLVLALLAAGKLGAPVLLLNT 130 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL---TVEKL 178 FA P L +V RE V +V+DEEF+ L + R +AWTD T++ + Sbjct 131 GFAKPQLTDVAAREKVRVLVHDEEFTDL----LGDIAGVDRYLAWTDSTPPADVPTLDDI 186 Query 179 VAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIV 238 +A G ++LLTSGTTGTPKGA LDR P R E T + Sbjct 187 IAGSDDHPLPAPPKPGGLVLLTSGTTGTPKGAPRPKVSPFDSAQFLDRIPLRVGEATFMG 246 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 AP+FHA G SQ +L+ +L CT+V RR+FDPEATL + H T LV+VP M RI+DL Sbjct 247 APLFHATGISQFILSCALGCTVVVRRKFDPEATLRGVAEHRCTALVLVPTMLQRILDLGP 306 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 E+ RYD SLR +GS + P+V + FGDVI+N Y +TE + ATP D + A Sbjct 307 EVIGRYDTSSLRIIFVAGSALAPEVGNRATELFGDVIHNLYGSTEVAVATVATPEDWKRA 366 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEV-GTIYVRNDSQFDGYTSGAAKDFHAGFMSSGD 417 P T G+P G + + D+ + V G ++V + F+GYT G K+ G +++GD Sbjct 367 PGTVGKPPVGCRVELYDEHGRRITRPYVTGRVFVGSGLAFEGYTDGRTKETINGLLATGD 426 Query 418 VGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLA 477 VG+ D +G LF+ GRDDEMIVSGGEN+YP+EVE L HPDV EAAVIGV D ++GQRL Sbjct 427 VGHFDADGLLFIDGRDDEMIVSGGENVYPVEVENVLVEHPDVREAAVIGVPDDEFGQRLK 486 Query 478 AFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 AFVV+K G + +++HVR+NLA YKVPRD+ LD+LPR TGK+LR L+ Sbjct 487 AFVVVKEGAELDADAVREHVRNNLARYKVPRDVEFLDQLPRNATGKVLRNSLE 539 >gi|134097880|ref|YP_001103541.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] gi|133910503|emb|CAM00616.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] Length=551 Score = 426 bits (1095), Expect = 5e-117, Method: Compositional matrix adjust. Identities = 229/520 (45%), Positives = 318/520 (62%), Gaps = 9/520 (1%) Query 15 RAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERG 74 R G++ P+RPD+ LRI+ A R G+ +A A R PDRP +IDE G +++ ++ R Sbjct 28 RQGVVRPMRPDKLLRILRAWLRWGITPPLAYAVGAIRHPDRPAVIDERGAISYAEVSLRT 87 Query 75 NALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTR 134 LA L+ G VGI+CRNH G ++ ++A ++G ++LLNT + LA V+ Sbjct 88 TRLANGLRERGIGESSRVGILCRNHHGAIETIVACGKLGTDVVLLNTGLSSSQLAAVLAE 147 Query 135 EGVDTVVYDEEFSATVDRALAEKPQATRIV-AWTD-EDHDLTVEKLVAAHAGRRPEHTGS 192 + VD +V D E+ DR L E P +V AWT+ TVE L+A + Sbjct 148 QRVDLLVLDAEY----DRHLPELPADLDVVLAWTEGSTRHWTVEHLIATSQAKALPRRPR 203 Query 193 HGKVILLTSGTTGTPKGARHSGG-GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLV 251 H ++I+LTSGTTGTPKGAR GIG ++ R P R+ E ++ AP+FH WG + Sbjct 204 HARMIVLTSGTTGTPKGARRPDPPGIGPAATVMSRIPLRSGERMLVCAPVFHTWGLAAFQ 263 Query 252 LASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRF 311 L + L T+V RRF+P L + R+ T + VPVM RI+DLPAE R R + SLR Sbjct 264 LGAVLGATLVLPRRFEPGHALSVAKRYQCTSMFAVPVMLQRILDLPAEERIRPE--SLRV 321 Query 312 AAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEI 371 A+SGS M D+ F FG V+YN Y +TE ++ ATP++LR AP TAGRP GT + Sbjct 322 VASSGSAMPADLATRFQRAFGPVLYNLYGSTEVSWVSIATPSELRAAPSTAGRPPRGTTV 381 Query 372 RILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVG 431 RILD+ TG G I+ ND F+GYTSG K+ G MS+GD+G +D +GRLFVVG Sbjct 382 RILDENGKPARTGATGRIFAGNDMLFEGYTSGGRKEVVDGLMSTGDLGRIDSSGRLFVVG 441 Query 432 RDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPE 491 R+D+MI+SGGEN+YP E E +A P+V E AV+GV+D ++GQRLAAFVVL+ + Sbjct 442 REDDMIISGGENVYPKETEDAIAALPEVREVAVVGVEDAEFGQRLAAFVVLQDDTRLDGD 501 Query 492 TLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 L++ VR +L+ + +PRD+ LDELPR TGK++ EL + Sbjct 502 DLRERVRGSLSRFAMPRDVVFLDELPRNATGKVVPRELHA 541 >gi|291007402|ref|ZP_06565375.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] Length=547 Score = 426 bits (1095), Expect = 5e-117, Method: Compositional matrix adjust. Identities = 229/520 (45%), Positives = 318/520 (62%), Gaps = 9/520 (1%) Query 15 RAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERG 74 R G++ P+RPD+ LRI+ A R G+ +A A R PDRP +IDE G +++ ++ R Sbjct 24 RQGVVRPMRPDKLLRILRAWLRWGITPPLAYAVGAIRHPDRPAVIDERGAISYAEVSLRT 83 Query 75 NALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTR 134 LA L+ G VGI+CRNH G ++ ++A ++G ++LLNT + LA V+ Sbjct 84 TRLANGLRERGIGESSRVGILCRNHHGAIETIVACGKLGTDVVLLNTGLSSSQLAAVLAE 143 Query 135 EGVDTVVYDEEFSATVDRALAEKPQATRIV-AWTD-EDHDLTVEKLVAAHAGRRPEHTGS 192 + VD +V D E+ DR L E P +V AWT+ TVE L+A + Sbjct 144 QRVDLLVLDAEY----DRHLPELPADLDVVLAWTEGSTRHWTVEHLIATSQAKALPRRPR 199 Query 193 HGKVILLTSGTTGTPKGARHSGG-GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLV 251 H ++I+LTSGTTGTPKGAR GIG ++ R P R+ E ++ AP+FH WG + Sbjct 200 HARMIVLTSGTTGTPKGARRPDPPGIGPAATVMSRIPLRSGERMLVCAPVFHTWGLAAFQ 259 Query 252 LASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRF 311 L + L T+V RRF+P L + R+ T + VPVM RI+DLPAE R R + SLR Sbjct 260 LGAVLGATLVLPRRFEPGHALSVAKRYQCTSMFAVPVMLQRILDLPAEERIRPE--SLRV 317 Query 312 AAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEI 371 A+SGS M D+ F FG V+YN Y +TE ++ ATP++LR AP TAGRP GT + Sbjct 318 VASSGSAMPADLATRFQRAFGPVLYNLYGSTEVSWVSIATPSELRAAPSTAGRPPRGTTV 377 Query 372 RILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVG 431 RILD+ TG G I+ ND F+GYTSG K+ G MS+GD+G +D +GRLFVVG Sbjct 378 RILDENGKPARTGATGRIFAGNDMLFEGYTSGGRKEVVDGLMSTGDLGRIDSSGRLFVVG 437 Query 432 RDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPE 491 R+D+MI+SGGEN+YP E E +A P+V E AV+GV+D ++GQRLAAFVVL+ + Sbjct 438 REDDMIISGGENVYPKETEDAIAALPEVREVAVVGVEDAEFGQRLAAFVVLQDDTRLDGD 497 Query 492 TLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 L++ VR +L+ + +PRD+ LDELPR TGK++ EL + Sbjct 498 DLRERVRGSLSRFAMPRDVVFLDELPRNATGKVVPRELHA 537 >gi|300788812|ref|YP_003769103.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|299798326|gb|ADJ48701.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|340530431|gb|AEK45636.1| acyl-CoA synthetase [Amycolatopsis mediterranei S699] Length=544 Score = 421 bits (1082), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 235/532 (45%), Positives = 319/532 (60%), Gaps = 19/532 (3%) Query 10 IATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGA----ARRCPDRPGLIDELGTL 65 + MRRAGL+ R D +R + A+R+ G FAGA ARR P G++DELG L Sbjct 21 VDVMRRAGLVPFPRLDEGVRSLVALRKFGP-----FAGANHISARRDPAAVGIVDELGPL 75 Query 66 TWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAG 125 T++QLD++ NALA A P +VV +CR+HRG V + A ++G +LL+NT FA Sbjct 76 TYKQLDDQSNALARAWSERGIRPGQVVAALCRDHRGLVLTMAASGKLGVRLLLMNTGFAK 135 Query 126 PALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLT------VEKLV 179 P LA+V REGV +VYD+EF+ +D A R +AW + DLT +++++ Sbjct 136 PQLADVAQREGVTALVYDQEFTGLLD---AIPDGVDRYLAWVEPGSDLTDRTVPVLDEII 192 Query 180 AAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVA 239 A+ R G +LLTSGTTGTPKGA LDR P R+ E T + A Sbjct 193 ASTDDRPWPAPAKPGGFVLLTSGTTGTPKGAPRPHTSALASAQFLDRIPLRSNEATYMGA 252 Query 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299 P+FH G SQ +L+ +L +V RR+F+PE L + H T LV+VP M RI+DLP E Sbjct 253 PLFHGTGLSQFILSFALGSKVVMRRKFNPEEALRGVAEHKCTALVLVPTMLQRIVDLPKE 312 Query 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359 +R +YD +LR +GS + PD+ + FG V++N Y +TE + ATP D AP Sbjct 313 VRQKYDTSALRIIFVAGSALSPDLGNRANEAFGPVVHNLYGSTEVAVATVATPEDWAKAP 372 Query 360 DTAGRPAEGTEIRILDQQFTEVPTGEV-GTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 T GR G ++ + D + ++ V G ++V + F GYT G K+ G +SSGDV Sbjct 373 GTVGRAPVGCKVALYDAKGGKITEPNVTGRVFVGSGLSFGGYTDGRHKEIIDGLLSSGDV 432 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 G+ DE+G LF+ GRDDEMIVSGGEN++PIEVE L DV EAAVIGV+D ++GQRL A Sbjct 433 GHFDEDGLLFIDGRDDEMIVSGGENVFPIEVENLLVEREDVIEAAVIGVEDPEFGQRLKA 492 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 FVV G + ++ +V+ NLA YKVPRD+ LDELPR TGK+LRT+LQ Sbjct 493 FVVRAEGAELDADEIRDYVKANLARYKVPRDVEFLDELPRNATGKVLRTKLQ 544 >gi|300785001|ref|YP_003765292.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|299794515|gb|ADJ44890.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|340526435|gb|AEK41640.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei S699] Length=671 Score = 418 bits (1075), Expect = 1e-114, Method: Compositional matrix adjust. Identities = 230/519 (45%), Positives = 310/519 (60%), Gaps = 6/519 (1%) Query 15 RAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERG 74 +AG++ P +P LR + ++ R G G+ ARR P+ L DE T+ +LD+R Sbjct 151 KAGVLTPAQPTGTLRQLRSVGRWGSTLAGGYEAVARRAPESLALCDERSERTFGELDDRT 210 Query 75 NALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTR 134 LAA L+ V +MCRNH V+A++A +++GA + L+NT A AE R Sbjct 211 TRLAAVLKRYDITEGSRVLLMCRNHNAMVEAMIACSKLGADVALMNTGLALGQAAEFALR 270 Query 135 EGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDED--HDLTVEKLVAAHAGRRPEHTGS 192 G V+ D EF+A + AE PQ + W D H T+E+L+ A R G Sbjct 271 HGSQLVLADAEFAALRGQLPAEIPQ---LWTWPPGDGWHGPTIEELIEAQPPARIAPPGK 327 Query 193 HGKVILLTSGTTGTPKGARH-SGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLV 251 G++++LTSGT+G PKGAR + + A+L P RA E ++ AP+FH WG + L Sbjct 328 PGRLVVLTSGTSGPPKGARRPTPHSVADAAAVLSEIPLRAGEPILVAAPLFHTWGLAALQ 387 Query 252 LASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRF 311 L +L +V RRFDPEATL +++R T L VP M R++DLP + R RYD SLR Sbjct 388 LGMALRAGLVLPRRFDPEATLSMVERQRCTALFAVPTMLRRLLDLPEQTRARYDLSSLRV 447 Query 312 AAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEI 371 A+SG+ + + FMD FGD++YN Y +TE A A P DLR A TAGRP GT I Sbjct 448 VASSGAGLPGRLGEEFMDAFGDILYNLYGSTEVSWAAIAGPRDLRAARGTAGRPPIGTAI 507 Query 372 RILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVG 431 R+LD+ T VP G G +YV N FDGYT G D G M +GD GY+D NG LFV G Sbjct 508 RVLDRAGTPVPPGTTGRLYVGNRLLFDGYTEGEQLDVRDGLMDTGDRGYVDANGLLFVQG 567 Query 432 RDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPE 491 R+DEMIVSGGEN+ P VE+ L T P+V EAAV+GV D +YGQRLAA++VL PG + Sbjct 568 REDEMIVSGGENVAPAPVEEVLLTLPEVREAAVVGVRDPKYGQRLAAYLVLVPGARLDAD 627 Query 492 TLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 T++ HVR+ LA + VPRD+ +DELPR TGK+++ L+ Sbjct 628 TVRSHVRERLARFAVPRDVVFVDELPRNATGKVVKRALR 666 >gi|121636183|ref|YP_976406.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988656|ref|YP_002643343.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|121491830|emb|CAL70292.1| Probable fatty-acid-CoA ligase fadD2 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771769|dbj|BAH24575.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|341600199|emb|CCC62868.1| probable fatty-acid-CoA ligase fadD2 [Mycobacterium bovis BCG str. Moreau RDJ] Length=560 Score = 416 bits (1069), Expect = 6e-114, Method: Compositional matrix adjust. Identities = 227/494 (46%), Positives = 302/494 (62%), Gaps = 16/494 (3%) Query 49 ARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLA 108 ARR P+R +IDE GTLT+ +LDE +A+A L A V I+ RNHR FV A Sbjct 71 ARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGEGVAILARNHRWFVIANYG 130 Query 109 VNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVD---------RALAEKPQ 159 R+GA I+LLN+ F+GP + EV REG ++YD+E++ V RAL P Sbjct 131 AARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD 190 Query 160 ATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSH-GKVILLTSGTTGTPKGA-RHSGGGI 217 + +DE T+ +L+A H+ P S +I+LTSGTTGTPKGA R++ + Sbjct 191 DDKPSGSSDE----TLAELIA-HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTL 245 Query 218 GTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDR 277 + IL P++A EVT++ +PMFHA G+ LA L T+V RRRF P L+ I++ Sbjct 246 APIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEK 305 Query 278 HHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYN 337 H AT +VVVPVM RI+D + + D SL+ SGS++ ++ + G VIYN Sbjct 306 HKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYN 365 Query 338 NYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQF 397 Y +TE A P DL+ P T G +G ++ILD+ EVP G VG I+V N F Sbjct 366 MYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPF 425 Query 398 DGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHP 457 +GYT G K G +SSGDVGY DE G L+V GRDDEMIVSGGEN++P EVE ++ HP Sbjct 426 EGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHP 485 Query 458 DVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELP 517 DV EAA IGVDD+++G RL AFVV KPG +T+KQ+VRD+LA YKVPR++ LDELP Sbjct 486 DVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELP 545 Query 518 RGITGKILRTELQS 531 R TGK+L+ EL+ Sbjct 546 RNPTGKVLKRELRK 559 >gi|300787810|ref|YP_003768101.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|299797324|gb|ADJ47699.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|340529382|gb|AEK44587.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei S699] Length=688 Score = 416 bits (1068), Expect = 7e-114, Method: Compositional matrix adjust. Identities = 230/523 (44%), Positives = 314/523 (61%), Gaps = 7/523 (1%) Query 11 ATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQL 70 + + RAG+++ RPD+ R + ++ + G G+ AA R PD L DE T+RQ+ Sbjct 160 SILLRAGVVSAGRPDKVARQLNSLAQWGATVAGGYQAAAARVPDELALHDERSVRTFRQV 219 Query 71 DERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAE 130 ER + LA AL L + +MCRNH +++ +A +++GA ++LLNT + ++ + Sbjct 220 QERSDRLANALSELGVVERDRIALMCRNHAAMIESFVAASKLGADVILLNTGLSAASVKD 279 Query 131 VVTREGVDTVVYDEEFSATVDRALAEKP-QATRIVAWTDEDHDL-TVEKLVAAHAGRRPE 188 V+ V+ D+EF+ T+ A P RI W D D TV++L+ A RP+ Sbjct 280 VLAEHQPSAVLADDEFAQTI----ANVPGDFARISTWPDADAGYPTVDELIHAAPADRPK 335 Query 189 HTGSHGKVILLTSGTTGTPKGARH-SGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGF 247 G++I+LTSGTTGTPKGAR + G+GT AILDR P R+ + ++ AP+FH WG Sbjct 336 PVERPGRLIVLTSGTTGTPKGARRPTPKGLGTAAAILDRIPLRSGDRLLVAAPLFHTWGL 395 Query 248 SQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGR 307 + + + +L ++ R+FD E TL I L VP+M RIMDLP IR RYD Sbjct 396 AAMQIGMALRASLALIRKFDAEETLRTIAEQKCDALFAVPIMLQRIMDLPERIRARYDLS 455 Query 308 SLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAE 367 SLR A+SGS M V +FMD FGDV+YN Y +TE + A PADLR AP TAGR Sbjct 456 SLRIVASSGSAMSGPFVTSFMDTFGDVLYNFYGSTEVSWASIADPADLRAAPTTAGRCPL 515 Query 368 GTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRL 427 GT + ILD+ VP G G I+V ND F+GYTSG A M+SGDVGYLD GRL Sbjct 516 GTRLAILDEDRKPVPPGGEGQIFVGNDMLFEGYTSGTDPARAADMMASGDVGYLDAAGRL 575 Query 428 FVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVS 487 FV GR DEMIVSGGEN++P VE+ L P V +AAV+GV D ++GQRLAA+VV + G S Sbjct 576 FVTGRADEMIVSGGENVFPRPVEEALVALPGVHDAAVVGVADAEWGQRLAAYVVPRRGAS 635 Query 488 ATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 E ++Q++ LA + VPRD+ + +LPR TGKIL+ L Sbjct 636 LHAEDIRQYIHHRLARFAVPRDVYFVPDLPRNATGKILKRLLH 678 >gi|15607411|ref|NP_214784.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv] gi|15839651|ref|NP_334688.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551] gi|31791448|ref|NP_853941.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] 64 more sequence titles Length=560 Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 227/494 (46%), Positives = 302/494 (62%), Gaps = 16/494 (3%) Query 49 ARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLA 108 ARR P+R +IDE GTLT+ +LDE +A+A L A V I+ RNHR FV A Sbjct 71 ARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYG 130 Query 109 VNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVD---------RALAEKPQ 159 R+GA I+LLN+ F+GP + EV REG ++YD+E++ V RAL P Sbjct 131 AARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD 190 Query 160 ATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSH-GKVILLTSGTTGTPKGA-RHSGGGI 217 + +DE T+ +L+A H+ P S +I+LTSGTTGTPKGA R++ + Sbjct 191 DDKPSGSSDE----TLAELIA-HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTL 245 Query 218 GTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDR 277 + IL P++A EVT++ +PMFHA G+ LA L T+V RRRF P L+ I++ Sbjct 246 APIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEK 305 Query 278 HHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYN 337 H AT +VVVPVM RI+D + + D SL+ SGS++ ++ + G VIYN Sbjct 306 HKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYN 365 Query 338 NYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQF 397 Y +TE A P DL+ P T G +G ++ILD+ EVP G VG I+V N F Sbjct 366 MYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPF 425 Query 398 DGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHP 457 +GYT G K G +SSGDVGY DE G L+V GRDDEMIVSGGEN++P EVE ++ HP Sbjct 426 EGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHP 485 Query 458 DVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELP 517 DV EAA IGVDD+++G RL AFVV KPG +T+KQ+VRD+LA YKVPR++ LDELP Sbjct 486 DVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELP 545 Query 518 RGITGKILRTELQS 531 R TGK+L+ EL+ Sbjct 546 RNPTGKVLKRELRK 559 >gi|289441647|ref|ZP_06431391.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T46] gi|289568180|ref|ZP_06448407.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T17] gi|289748751|ref|ZP_06508129.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T92] gi|289756337|ref|ZP_06515715.1| substrate-CoA ligase [Mycobacterium tuberculosis EAS054] gi|289414566|gb|EFD11806.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T46] gi|289541933|gb|EFD45582.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T17] gi|289689338|gb|EFD56767.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T92] gi|289696924|gb|EFD64353.1| substrate-CoA ligase [Mycobacterium tuberculosis EAS054] Length=560 Score = 414 bits (1065), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 227/494 (46%), Positives = 302/494 (62%), Gaps = 16/494 (3%) Query 49 ARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLA 108 ARR P+R +IDE GTLT+ +LDE +A+A L A V I+ RNHR FV A Sbjct 71 ARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYG 130 Query 109 VNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVD---------RALAEKPQ 159 R+GA I+LLN+ F+GP + EV REG ++YD+E++ V RAL P Sbjct 131 AARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD 190 Query 160 ATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSH-GKVILLTSGTTGTPKGA-RHSGGGI 217 + +DE T+ +L+A H+ P S +I+LTSGTTGTPKGA R++ + Sbjct 191 DDKPSGSSDE----TLAELIA-HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTL 245 Query 218 GTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDR 277 + IL P++A EVT++ +PMFHA G+ LA L T+V RRRF P L+ I++ Sbjct 246 APIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEK 305 Query 278 HHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYN 337 H AT +VVVPVM RI+D + + D SL+ SGS++ ++ + G VIYN Sbjct 306 HKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYN 365 Query 338 NYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQF 397 Y +TE A P DL+ P T G +G ++ILD+ EVP G VG I+V N F Sbjct 366 MYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPF 425 Query 398 DGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHP 457 +GYT G K G +SSGDVGY DE G L+V GRDDEMIVSGGEN++P EVE ++ HP Sbjct 426 EGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEGLISGHP 485 Query 458 DVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELP 517 DV EAA IGVDD+++G RL AFVV KPG +T+KQ+VRD+LA YKVPR++ LDELP Sbjct 486 DVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELP 545 Query 518 RGITGKILRTELQS 531 R TGK+L+ EL+ Sbjct 546 RNPTGKVLKRELRK 559 >gi|291300476|ref|YP_003511754.1| AMP-dependent synthetase and ligase [Stackebrandtia nassauensis DSM 44728] gi|290569696|gb|ADD42661.1| AMP-dependent synthetase and ligase [Stackebrandtia nassauensis DSM 44728] Length=534 Score = 414 bits (1065), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 226/517 (44%), Positives = 313/517 (61%), Gaps = 10/517 (1%) Query 11 ATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQL 70 +TM R GL+ P RPDR +R V+ + R G+G FA AARR P+ ++DE G +++ +L Sbjct 20 STMARRGLLTPGRPDRVVRQVSTLARWGLGLAGEFASAARRDPEWTAVVDEDGPVSFAEL 79 Query 71 DERGNALAAAL-QALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALA 129 DER + LA L + P GPPRV ++CRNH G + L+A ++GA +L NT + + Sbjct 80 DERTDRLARVLAEGRPEGPPRV-AVLCRNHTGMIATLIACGKLGADAVLFNTGLSAQQVR 138 Query 130 EVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHD-LTVEKLVAAHAGRRPE 188 + V + +V D EF L + P R++A + D L A G P Sbjct 139 QAVDDHDIAVLVADTEFLP-----LPDLPDGVRVIAAEGDGADGLRALAEAAEPGGHSPP 193 Query 189 HTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFS 248 + G+ I+LTSGTTGTPKGAR + +L A+L R P + + I AP+FH WG++ Sbjct 194 --AATGRTIVLTSGTTGTPKGARRPKPALHSLTALLSRIPLKVGDRIHIAAPIFHTWGYA 251 Query 249 QLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRS 308 L LA ++ TIV RRRFDPE +L + H T + VPVM R+++LP E+R+ D S Sbjct 252 ALQLAIAMRATIVLRRRFDPEPSLRTLSEHDCTAMFAVPVMLQRLLELPPEVRDGCDTAS 311 Query 309 LRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEG 368 LR A SGS D+ FMD FGDV+YN Y TE I+ ATP +LR PDT+GRP G Sbjct 312 LRVVATSGSSYPGDLATRFMDAFGDVLYNLYGTTEVSWISIATPEELRAHPDTSGRPPHG 371 Query 369 TEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLF 428 T + +LD+ EV G G I+V N+ F+GYT G+ + G M SGD+G+ DE+G L+ Sbjct 372 TTVLLLDEDGREVDRGVPGRIFVGNEMLFEGYTDGSRRSTFDGTMDSGDLGHRDESGLLY 431 Query 429 VVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSA 488 V GR D+MI+SGGEN++P EVE LA P V E AV+GV D+++GQRL A VV+ G Sbjct 432 VDGRADDMIISGGENVFPSEVENLLARLPQVREVAVVGVADEEFGQRLVAHVVVAEGHEL 491 Query 489 TPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKIL 525 ET++ HVR +LA + VPRD+ L++LPR TGK++ Sbjct 492 DAETVRDHVRTHLARFSVPRDVRFLEQLPRNATGKVV 528 >gi|298523738|ref|ZP_07011147.1| acyl-CoA synthetase [Mycobacterium tuberculosis 94_M4241A] gi|298493532|gb|EFI28826.1| acyl-CoA synthetase [Mycobacterium tuberculosis 94_M4241A] Length=560 Score = 414 bits (1064), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 226/494 (46%), Positives = 302/494 (62%), Gaps = 16/494 (3%) Query 49 ARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLA 108 ARR P+R ++DE GTLT+ +LDE +A+A L A V I+ RNHR FV A Sbjct 71 ARRAPNRAAVMDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYG 130 Query 109 VNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVD---------RALAEKPQ 159 R+GA I+LLN+ F+GP + EV REG ++YD+E++ V RAL P Sbjct 131 AARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD 190 Query 160 ATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSH-GKVILLTSGTTGTPKGA-RHSGGGI 217 + +DE T+ +L+A H+ P S +I+LTSGTTGTPKGA R++ + Sbjct 191 DDKPSGSSDE----TLAELIA-HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTL 245 Query 218 GTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDR 277 + IL P++A EVT++ +PMFHA G+ LA L T+V RRRF P L+ I++ Sbjct 246 APIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEK 305 Query 278 HHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYN 337 H AT +VVVPVM RI+D + + D SL+ SGS++ ++ + G VIYN Sbjct 306 HKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYN 365 Query 338 NYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQF 397 Y +TE A P DL+ P T G +G ++ILD+ EVP G VG I+V N F Sbjct 366 MYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPF 425 Query 398 DGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHP 457 +GYT G K G +SSGDVGY DE G L+V GRDDEMIVSGGEN++P EVE ++ HP Sbjct 426 EGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHP 485 Query 458 DVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELP 517 DV EAA IGVDD+++G RL AFVV KPG +T+KQ+VRD+LA YKVPR++ LDELP Sbjct 486 DVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELP 545 Query 518 RGITGKILRTELQS 531 R TGK+L+ EL+ Sbjct 546 RNPTGKVLKRELRK 559 >gi|302526241|ref|ZP_07278583.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4] gi|302435136|gb|EFL06952.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4] Length=690 Score = 413 bits (1061), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 222/521 (43%), Positives = 316/521 (61%), Gaps = 5/521 (0%) Query 12 TMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLD 71 T+ RAG++A RPD+ ++ ++++ R G G+ A R D + DE T T+ ++D Sbjct 164 TLVRAGVLAAGRPDKVVKQLSSLARWGATLAGGYLAATARGADDVAVHDERHTRTFGEID 223 Query 72 ERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEV 131 ER N LA AL AL V +MCRNH V+A + +++GA ++LLNT + A+ EV Sbjct 224 ERSNQLANALAALDVEAGSRVALMCRNHAAMVEAFVGCSKLGADVVLLNTGLSPAAVEEV 283 Query 132 VTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL-TVEKLVAAHAGRRPEHT 190 +T+ V+ D+EF+ + E P R+ W D D T+++L+ RP+ + Sbjct 284 LTQHPPAAVLADDEFAPIIASVPGEFP---RVSTWDDADQGYRTLDELLQDAPTTRPKPS 340 Query 191 GSHGKVILLTSGTTGTPKGARH-SGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQ 249 G++++LTSGTTG PKGAR + G+ T +L R P RA + + AP+FH+WG + Sbjct 341 EREGRIVVLTSGTTGAPKGARRPTPKGVSTSATVLSRIPLRARDKIAVAAPLFHSWGLAA 400 Query 250 LVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSL 309 + L +L + R+FD E TL I H L VP+M RI+DLP +R+RYD SL Sbjct 401 MQLGMALRAELSLIRKFDAEHTLRTIAEHRCDALFAVPIMLQRILDLPERVRSRYDLSSL 460 Query 310 RFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGT 369 R A+SGS M V +FMD FGD++YN Y +TE + A PADLR AP +AGR GT Sbjct 461 RIVASSGSAMPGAFVTSFMDTFGDILYNFYGSTEVSWASIADPADLRAAPTSAGRCPPGT 520 Query 370 EIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFV 429 + ILD+ VP G+ G I+V ND FDGYT+G++ M++GDVGY D +GRLFV Sbjct 521 RVAILDEDRRPVPPGDEGQIFVGNDMLFDGYTNGSSVPRAHDLMATGDVGYQDASGRLFV 580 Query 430 VGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSAT 489 GR DEMIVSGGEN++P VE+ LA P V++AAV+GV D ++GQRLAA+VVL+ G Sbjct 581 TGRADEMIVSGGENVFPRPVEEALAALPGVSDAAVVGVPDDEFGQRLAAYVVLRRGARMH 640 Query 490 PETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQ 530 E ++ ++ LA + VPRD+ + ELPR TGKI++ L Sbjct 641 AEDVRHYIHQRLARFAVPRDVYFVPELPRNATGKIVKRLLN 681 >gi|297559035|ref|YP_003678009.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296843483|gb|ADH65503.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=546 Score = 413 bits (1061), Expect = 5e-113, Method: Compositional matrix adjust. Identities = 232/534 (44%), Positives = 308/534 (58%), Gaps = 7/534 (1%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61 R R + + RAG+++P RPDR +R + A+R G G+A A R PD ++DE Sbjct 13 RTRHVLETVRVLVRAGVLSPGRPDRVVRQLRALRTWGATIAGGYAAANERVPDAVAVVDE 72 Query 62 LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121 LG T+R++D RG LA L+ G VG++CRNH GFV ++A R+GA +LLNT Sbjct 73 LGPTTFREMDLRGRELARDLRRAGVGAGARVGVLCRNHSGFVQTMVACGRLGADTVLLNT 132 Query 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAE-KPQATRIVAWTD-EDHDLTVEKLV 179 + LA V GV VV D EF AE P R+ AW + D V Sbjct 133 GLSAGQLAAAVGGNGVSVVVADAEFEGMC----AELDPGVVRVTAWGEPSDGGPGVPWRA 188 Query 180 AAHAGRRPEHTGSHGKVILLTSGTTGTPKGARH-SGGGIGTLKAILDRTPWRAEEVTVIV 238 + PE G++++LTSGTTG PKGAR + G ++L R P R+ + ++ Sbjct 189 REVSESDPEPPERPGRLVVLTSGTTGAPKGARRPTPRGPQDAASVLSRIPLRSSDRILVS 248 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 AP+FH WG + + L S+ T+V RR F+PE L + T L VPVM RIMDLP Sbjct 249 APIFHTWGLAGVQLGMSMRATLVMRRLFEPEDALRTVQEERCTALFAVPVMLRRIMDLPR 308 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 R RYD SLR A SGS M P ++ FMD FGDV+YN Y +TE ATP ++R + Sbjct 309 STRERYDTSSLRIVACSGSAMSPQLITGFMDAFGDVLYNLYGSTEVSWATIATPGEMRLS 368 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 P TAGRP GT I +LD EVP G G+I+V ND FDGYT G ++ G M +GD Sbjct 369 PTTAGRPPLGTRIAVLDPGGVEVPPGTEGSIHVGNDMLFDGYTDGRSRRVADGLMETGDR 428 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 G++D NG L V GRDD+MIVSGGEN++P VE+ + T P+V E V GV D+++GQR AA Sbjct 429 GHVDANGLLHVAGRDDDMIVSGGENVFPRPVEEAIVTLPEVREVVVTGVPDEEFGQRFAA 488 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSR 532 +VV G P ++ HVR L + VPRD+ V+DELPR TGK+++ L R Sbjct 489 YVVPHEGRGVDPNQVRTHVRRVLGRFSVPRDVVVVDELPRNATGKVVKRLLPRR 542 >gi|269124818|ref|YP_003298188.1| AMP-dependent synthetase and ligase [Thermomonospora curvata DSM 43183] gi|268309776|gb|ACY96150.1| AMP-dependent synthetase and ligase [Thermomonospora curvata DSM 43183] Length=527 Score = 412 bits (1058), Expect = 1e-112, Method: Compositional matrix adjust. Identities = 242/531 (46%), Positives = 316/531 (60%), Gaps = 11/531 (2%) Query 2 RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREG-MGFTAGFAGAARRCPDRPGLID 60 RIRQ + RRAGLI L P + A+R G +G A A R R L+D Sbjct 3 RIRQVLEGLTAARRAGLIG-LPPRAVAPSIRALRAYGPLGAAATMN--ALRFGSRTALVD 59 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 E GTLT+ L+ R NALA A +A GP VGI+CRNHRG +DA+ A +IGA +L LN Sbjct 60 EHGTLTFADLERRSNALANAWRARGLGPASRVGILCRNHRGLLDAMTAAAKIGAGVLFLN 119 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 T F GP L + V REGV +V+DEEF+ A A PQ R VAWTD +E+L+A Sbjct 120 TDFGGPQLVQTVEREGVTALVHDEEFTPVA--AGAPAPQG-RFVAWTDRPGGGDLERLIA 176 Query 181 AHAGRRPEHTGSHGKVILLTSGTTGTPKGA-RHSGGGIGTLK-AILDRTPWRAEEVTVIV 238 P G HG +++LTSGT+G PKGA R SG L I+ R P+R E + Sbjct 177 EGDPAPPPAPGRHGSLVILTSGTSGAPKGAPRSSGPSAAWLPVGIVHRIPFRPGESVFVG 236 Query 239 APMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPA 298 PMFH WG + +++ ++ RRRFD +A LDL++RH LV VPVM R++ A Sbjct 237 PPMFHGWGLTAMLVTLGTGSVLLLRRRFDADAVLDLLERHRVRALVAVPVMLSRLLAADA 296 Query 299 EIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTA 358 NR R LR A G+ + P + M +FG V+YN Y +TEA I+ ATP DLR A Sbjct 297 RRENRPRLR-LRIIATGGAALSPALAERVMARFGPVLYNFYGSTEASSISIATPEDLRAA 355 Query 359 PDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDV 418 P GRP GT ++ILD EVP G G I++ + +F GYT G K M+ GD+ Sbjct 356 PGCVGRPTLGTTVKILDASGREVPPGVTGQIHIDSPLRFAGYTGGGTKPTAGKLMAVGDL 415 Query 419 GYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAA 478 G+LD GRLF+ GR D+MIVSGGEN+YP EVE+ LA HP + EAAV+GV D+++GQRL A Sbjct 416 GHLDAAGRLFIDGRADDMIVSGGENVYPAEVEELLAGHPGIREAAVVGVPDEEFGQRLRA 475 Query 479 FVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTEL 529 +VV + E ++++V NLA YKVPRD+ ++ELPR TGK+L+ L Sbjct 476 YVVAA-DTALGEEEVRRYVSANLARYKVPRDVVFVEELPRTSTGKVLKRLL 525 >gi|284041810|ref|YP_003392150.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] gi|283946031|gb|ADB48775.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] Length=542 Score = 409 bits (1050), Expect = 1e-111, Method: Compositional matrix adjust. Identities = 245/538 (46%), Positives = 321/538 (60%), Gaps = 10/538 (1%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGF-AGAARRCPDRPGLI 59 +R R + RAG++ P P + R + + R GF A AARR DRPGLI Sbjct 9 LRARNEVTYVTACVRAGVVRPEPPRSFARNLRDVAR--YGFVGALPALAARRRGDRPGLI 66 Query 60 DELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLL 119 DE GTLT+ QLD R NALA +A V I+ RNHRGFV+A A R GA ++LL Sbjct 67 DERGTLTFSQLDRRANALANGWRAHGLRAGDGVAILARNHRGFVEATTAAARCGARVVLL 126 Query 120 NTSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDL--TVEK 177 NT FAGP + +V REGVD +V+D+E++ +D +P+ R AWTD+ T+E Sbjct 127 NTDFAGPQIRDVAAREGVDLLVHDDEYATFLD---GIEPRLGRWRAWTDDGAAAPGTLEA 183 Query 178 LVAAHAGRRPEHTGSHGKVILLTSGTTGTPKGA-RHSGGGIGTLKAILDRTPWRAEEVTV 236 L+A + P S K+++LTSGTTGTPKGA R + L A+L P+RA E TV Sbjct 184 LIARGSPAPPPRPASEAKLVVLTSGTTGTPKGAPRTVPKSLQPLGALLSVVPFRAGETTV 243 Query 237 IVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDL 296 + AP+FH+ GF Q LA +L T+V RRRFDP LD + RH A+ +VVVPVM R++ L Sbjct 244 VAAPLFHSLGFVQGQLALALGSTLVLRRRFDPAVLLDDLARHRASAVVVVPVMLRRVLAL 303 Query 297 PAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLR 356 + D +LR +GS++ ++ FG +YN Y +TE ATPADL Sbjct 304 GDDAVAGRDLSALRIVFVAGSQLGAELCERTTAAFGPRVYNLYGSTEVAYATIATPADLA 363 Query 357 TAPDTAGRPAEGTEIRILDQQFTEVP-TGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSS 415 P GRP G +R+ D V G G I+V N +F+GYT G +K+ G MSS Sbjct 364 VEPGCVGRPPPGAVVRLYDDAGAPVTGPGHSGRIFVGNGFEFEGYTGGGSKETIDGLMSS 423 Query 416 GDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQR 475 GDVG+ D GRLFV GRDDEMIVSGGEN++P EVE+ L HP V EAA+I V+D+ +GQR Sbjct 424 GDVGHFDAAGRLFVDGRDDEMIVSGGENVFPAEVEELLHRHPAVEEAALIAVEDEAWGQR 483 Query 476 LAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533 L AFVV++ G + +K VR+NLA YKVPR+ LD LPR TGK+L+ EL + V Sbjct 484 LRAFVVVRAGEQLGEDAVKAFVRENLARYKVPREAVFLDALPRNPTGKVLKRELAAIV 541 >gi|54025764|ref|YP_120006.1| acyl-CoA synthetase [Nocardia farcinica IFM 10152] gi|54017272|dbj|BAD58642.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152] Length=541 Score = 408 bits (1049), Expect = 1e-111, Method: Compositional matrix adjust. Identities = 237/510 (47%), Positives = 308/510 (61%), Gaps = 13/510 (2%) Query 21 PLRPDRYLRIVAAMRREGMGFTAGFAG-AARRCPDRPGLIDELGTLTWRQLDERGNALAA 79 P RPDR + A+ R G+ G G AA R DR ++DE G +++R+LDER ALA Sbjct 32 PERPDRLAGMGLAVVRSGL--LGGLVGVAAVRYRDRTAVLDERGRVSFRELDERTTALAN 89 Query 80 ALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTREGVDT 139 A +A V ++ RNHRGF A+ A + GA I+L+NT F L EV+ REG D Sbjct 90 AWRARGLRDGEGVAVLTRNHRGFHYAVFAAAKCGARIILVNTDFGAGQLREVLAREGADL 149 Query 140 VVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAHA---GRRPEHTGSHGKV 196 VV+DEEF+ + +P+ R AWTD T++ L+A A RRP + ++ Sbjct 150 VVHDEEFTGLLGDL---RPRRGRYRAWTDAPAVDTLDNLIAGGARTPARRPR---TPARI 203 Query 197 ILLTSGTTGTPKGA-RHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASS 255 +LLTSGTTGTPKGA R + L +L R P R EVT AP+FH GF+ VLA Sbjct 204 VLLTSGTTGTPKGAPRREPTSLSPLGGLLARVPLRVREVTECPAPLFHTLGFAHAVLALG 263 Query 256 LACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAAS 315 T+V RR+FDPEA LD + RH A+ LVVVPVM R++D R + LR + Sbjct 264 FGTTLVIRRKFDPEAVLDSLVRHRASTLVVVPVMLRRLVDADPHARAHRELSRLRVVFVA 323 Query 316 GSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILD 375 GS++ + + + FG V+YN Y +TEA ATPADL AP GRP G + ILD Sbjct 324 GSQLGAPLCLRATEAFGPVLYNVYGSTEAAYATIATPADLAEAPGCVGRPVPGAVVAILD 383 Query 376 QQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDE 435 E+P G G I+V ND QF+GYT G K G M++GD+G++D GRLFV GR+D+ Sbjct 384 AADRELPAGHTGRIFVGNDYQFEGYTGGGDKPRVRGLMATGDLGHVDAAGRLFVDGREDD 443 Query 436 MIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQ 495 MIVSGGEN++P EVE LA HP VAEA+ GVDD +YGQRL VVL+PG + T E ++ Sbjct 444 MIVSGGENVFPGEVEDLLAAHPAVAEASAFGVDDDEYGQRLRVAVVLRPGHALTAEQVRD 503 Query 496 HVRDNLANYKVPRDIAVLDELPRGITGKIL 525 HVR +LA YKVPRD+ L ELPR +GK+L Sbjct 504 HVRTHLARYKVPRDVLFLPELPRNPSGKVL 533 >gi|118473796|ref|YP_885010.1| acyl-CoA synthetase [Mycobacterium smegmatis str. MC2 155] gi|118175083|gb|ABK75979.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155] Length=548 Score = 407 bits (1046), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 234/531 (45%), Positives = 314/531 (60%), Gaps = 19/531 (3%) Query 13 MRRAGLIAPLRPDRYLRIVAAMRREG-MGFTAGFAGAARRCPDRPGLIDELGTLTWRQLD 71 M AG + P L +VA +R G +G ARR P+R +ID+ G T+ +LD Sbjct 22 MFEAGALRLEPPQHMLALVADIRTWGEIGMIPALN--ARRHPNRVAVIDDEGEFTFGELD 79 Query 72 ERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEV 131 +ALA L A VGI+ RNHR F+ +L R+GA I++LNT F+GP + EV Sbjct 80 AAAHALANELLARGVRGGDGVGILARNHRWFLVSLYGAARVGARIIMLNTEFSGPQIKEV 139 Query 132 VTREGVDTVVYDEEFSATVD---------RALAEKPQATRIVAWTDEDHDLTVEKLVAAH 182 REG ++YD+E++A V RAL P TDE T+ +++A Sbjct 140 AAREGARVIIYDDEYTAAVAQAETELGKLRALGTNPDKEEPSGSTDE----TLAEVIA-R 194 Query 183 AGRRPEHTGS-HGKVILLTSGTTGTPKGA-RHSGGGIGTLKAILDRTPWRAEEVTVIVAP 240 +G+RP S H +I+LTSGTTGTPKGA R + + + +L P++A EVT + AP Sbjct 195 SGKRPAPKASRHASIIILTSGTTGTPKGANRAAPPSLAPIGGVLSHVPFKAGEVTALPAP 254 Query 241 MFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEI 300 MFHA GF +A L T+V RRRF P L+ I++H T VVVPVM R++D ++ Sbjct 255 MFHALGFLHATIAMMLGSTLVLRRRFKPATVLEDIEKHKVTAAVVVPVMLSRMLDHLEKM 314 Query 301 RNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD 360 + D SLR SGS++ ++ + + G VIYN Y +TE A P DL P Sbjct 315 PQKPDLSSLRIMFVSGSQLGAELATRALKELGPVIYNLYGSTEIAFATIARPQDLSRNPA 374 Query 361 TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGY 420 T G +G ++ILD E+P GEVG I+VRN F GYT G K G MSSGDVGY Sbjct 375 TVGPVVKGITVKILDDNGKELPQGEVGRIFVRNTFPFKGYTGGGGKQIIDGMMSSGDVGY 434 Query 421 LDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFV 480 DE+G L++ GRDDEMIVSGGEN++P EVE ++ HP+V EA IGVDD+++G RL AFV Sbjct 435 FDEHGLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVIEATAIGVDDKEWGARLRAFV 494 Query 481 VLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQS 531 V G S T + +K +VRD+LA YKVPR++ LDELPR TGKIL+ EL++ Sbjct 495 VKAAGSSLTEDDVKAYVRDHLARYKVPREVIFLDELPRNPTGKILKRELRN 545 >gi|289569445|ref|ZP_06449672.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T17] gi|289543199|gb|EFD46847.1| long-chain fatty-acid-CoA ligase fadD12 [Mycobacterium tuberculosis T17] Length=200 Score = 403 bits (1035), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 200/200 (100%), Positives = 200/200 (100%), Gaps = 0/200 (0%) Query 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID Sbjct 1 MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLID 60 Query 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN Sbjct 61 ELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLN 120 Query 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA Sbjct 121 TSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVA 180 Query 181 AHAGRRPEHTGSHGKVILLT 200 AHAGRRPEHTGSHGKVILLT Sbjct 181 AHAGRRPEHTGSHGKVILLT 200 Lambda K H 0.321 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1174515528420 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40