BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1451
Length=308
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608589|ref|NP_215967.1| protoheme IX farnesyltransferase [M... 608 4e-172
gi|31792645|ref|NP_855138.1| protoheme IX farnesyltransferase [M... 607 9e-172
gi|289753533|ref|ZP_06512911.1| protoheme IX farnesyltransferase... 586 1e-165
gi|339298065|gb|AEJ50175.1| protoheme IX farnesyltransferase [My... 578 5e-163
gi|289757559|ref|ZP_06516937.1| protoheme IX farnesyltransferase... 535 5e-150
gi|289569474|ref|ZP_06449701.1| cytochrome C oxidase assembly fa... 530 1e-148
gi|183982268|ref|YP_001850559.1| cytochrome C oxidase assembly f... 499 2e-139
gi|254821677|ref|ZP_05226678.1| protoheme IX farnesyltransferase... 499 2e-139
gi|118471528|ref|YP_887420.1| protoheme IX farnesyltransferase [... 498 4e-139
gi|118617455|ref|YP_905787.1| protoheme IX farnesyltransferase [... 498 7e-139
gi|15827232|ref|NP_301495.1| protoheme IX farnesyltransferase [M... 496 2e-138
gi|182639251|sp|Q9CCN4.2|COXX_MYCLE RecName: Full=Protoheme IX f... 496 2e-138
gi|342858743|ref|ZP_08715398.1| protoheme IX farnesyltransferase... 494 5e-138
gi|466878|gb|AAA17123.1| cyoE [Mycobacterium leprae] 494 8e-138
gi|2398716|emb|CAB16181.1| cytochrome c oxidase assembly factor ... 491 7e-137
gi|254775771|ref|ZP_05217287.1| protoheme IX farnesyltransferase... 488 4e-136
gi|41407277|ref|NP_960113.1| protoheme IX farnesyltransferase [M... 487 9e-136
gi|240171360|ref|ZP_04750019.1| protoheme IX farnesyltransferase... 484 9e-135
gi|182639259|sp|A0QHX0.2|COXX_MYCA1 RecName: Full=Protoheme IX f... 475 4e-132
gi|108799382|ref|YP_639579.1| protoheme IX farnesyltransferase [... 474 6e-132
gi|126435039|ref|YP_001070730.1| protoheme IX farnesyltransferas... 472 4e-131
gi|296170687|ref|ZP_06852262.1| protoheme IX farnesyltransferase... 470 2e-130
gi|118462366|ref|YP_882508.1| protoheme IX farnesyltransferase [... 459 4e-127
gi|333990905|ref|YP_004523519.1| cytochrome C oxidase assembly f... 456 2e-126
gi|120403705|ref|YP_953534.1| protoheme IX farnesyltransferase [... 451 5e-125
gi|289750010|ref|ZP_06509388.1| cytochrome C oxidase assembly fa... 447 9e-124
gi|169629842|ref|YP_001703491.1| protoheme IX farnesyltransferas... 446 2e-123
gi|145224275|ref|YP_001134953.1| protoheme IX farnesyltransferas... 443 2e-122
gi|289745200|ref|ZP_06504578.1| protoheme IX farnesyltransferase... 439 3e-121
gi|54025542|ref|YP_119784.1| protoheme IX farnesyltransferase [N... 437 8e-121
gi|333919564|ref|YP_004493145.1| protoheme IX farnesyltransferas... 421 8e-116
gi|226306533|ref|YP_002766493.1| protoheme IX farnesyltransferas... 417 9e-115
gi|229493657|ref|ZP_04387442.1| protoheme IX farnesyltransferase... 416 2e-114
gi|226366377|ref|YP_002784160.1| protoheme IX farnesyltransferas... 413 2e-113
gi|312139618|ref|YP_004006954.1| protoheme ix farnesyltransferas... 411 7e-113
gi|182639245|sp|Q0S0I5.2|COXX_RHOSR RecName: Full=Protoheme IX f... 410 2e-112
gi|111024137|ref|YP_707109.1| protoheme IX farnesyltransferase [... 409 2e-112
gi|296140221|ref|YP_003647464.1| protoheme IX farnesyltransferas... 385 7e-105
gi|257055629|ref|YP_003133461.1| protoheme IX farnesyltransferas... 383 2e-104
gi|300784716|ref|YP_003765007.1| protoheme IX farnesyltransferas... 376 2e-102
gi|262202302|ref|YP_003273510.1| protoheme IX farnesyltransferas... 373 2e-101
gi|302525916|ref|ZP_07278258.1| protoheme IX farnesyltransferase... 373 2e-101
gi|134098731|ref|YP_001104392.1| protoheme IX farnesyltransferas... 372 3e-101
gi|296392902|ref|YP_003657786.1| protoheme IX farnesyltransferas... 372 6e-101
gi|317507847|ref|ZP_07965548.1| protoheme IX farnesyltransferase... 371 1e-100
gi|343924591|ref|ZP_08764139.1| protoheme IX farnesyltransferase... 370 1e-100
gi|256379192|ref|YP_003102852.1| protoheme IX farnesyltransferas... 366 2e-99
gi|289574130|ref|ZP_06454357.1| protoheme IX farnesyltransferase... 360 2e-97
gi|339294427|gb|AEJ46538.1| protoheme IX farnesyltransferase [My... 357 2e-96
gi|326382197|ref|ZP_08203889.1| protoheme IX farnesyltransferase... 353 1e-95
>gi|15608589|ref|NP_215967.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
H37Rv]
gi|15840911|ref|NP_335948.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
CDC1551]
gi|148661243|ref|YP_001282766.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
H37Ra]
50 more sequence titles
Length=308
Score = 608 bits (1567), Expect = 4e-172, Method: Compositional matrix adjust.
Identities = 307/308 (99%), Positives = 308/308 (100%), Gaps = 0/308 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
+NVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL
Sbjct 1 MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC
Sbjct 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL
Sbjct 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL
Sbjct 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS
Sbjct 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
Query 301 VIALPTLH 308
VIALPTLH
Sbjct 301 VIALPTLH 308
>gi|31792645|ref|NP_855138.1| protoheme IX farnesyltransferase [Mycobacterium bovis AF2122/97]
gi|121637381|ref|YP_977604.1| protoheme IX farnesyltransferase [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224989856|ref|YP_002644543.1| protoheme IX farnesyltransferase [Mycobacterium bovis BCG str.
Tokyo 172]
11 more sequence titles
Length=308
Score = 607 bits (1564), Expect = 9e-172, Method: Compositional matrix adjust.
Identities = 306/308 (99%), Positives = 307/308 (99%), Gaps = 0/308 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
+NVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL
Sbjct 1 MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
VGGMMAA GANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC
Sbjct 61 VGGMMAATGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL
Sbjct 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL
Sbjct 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS
Sbjct 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
Query 301 VIALPTLH 308
VIALPTLH
Sbjct 301 VIALPTLH 308
>gi|289753533|ref|ZP_06512911.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
EAS054]
gi|289694120|gb|EFD61549.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
EAS054]
Length=297
Score = 586 bits (1511), Expect = 1e-165, Method: Compositional matrix adjust.
Identities = 296/297 (99%), Positives = 297/297 (100%), Gaps = 0/297 (0%)
Query 12 VTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN 71
+TGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN
Sbjct 1 MTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN 60
Query 72 TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL 131
TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL
Sbjct 61 TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL 120
Query 132 VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP 191
VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP
Sbjct 121 VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP 180
Query 192 PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV 251
PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV
Sbjct 181 PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV 240
Query 252 ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
Sbjct 241 ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 297
>gi|339298065|gb|AEJ50175.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
CCDC5180]
Length=292
Score = 578 bits (1489), Expect = 5e-163, Method: Compositional matrix adjust.
Identities = 292/292 (100%), Positives = 292/292 (100%), Gaps = 0/292 (0%)
Query 17 MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV 76
MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV
Sbjct 1 MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV 60
Query 77 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 136
ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF
Sbjct 61 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 120
Query 137 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA 196
YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA
Sbjct 121 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA 180
Query 197 LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG 256
LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG
Sbjct 181 LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG 240
Query 257 GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
Sbjct 241 GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 292
>gi|289757559|ref|ZP_06516937.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
T85]
gi|289713123|gb|EFD77135.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
T85]
Length=297
Score = 535 bits (1377), Expect = 5e-150, Method: Compositional matrix adjust.
Identities = 276/292 (95%), Positives = 277/292 (95%), Gaps = 1/292 (0%)
Query 18 STLLAYLALTKPRVIELLLVTA-IPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV 76
STLLAYLALTKPRV + DRGAIHPLLMLNTLVGGMMAAAGANTLNCV
Sbjct 6 STLLAYLALTKPRVHRAAVGHPRYRRCCWPDRGAIHPLLMLNTLVGGMMAAAGANTLNCV 65
Query 77 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 136
ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF
Sbjct 66 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 125
Query 137 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA 196
YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA
Sbjct 126 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA 185
Query 197 LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG 256
LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG
Sbjct 186 LAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAG 245
Query 257 GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
Sbjct 246 GWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 297
>gi|289569474|ref|ZP_06449701.1| cytochrome C oxidase assembly factor ctaB [Mycobacterium tuberculosis
T17]
gi|289543228|gb|EFD46876.1| cytochrome C oxidase assembly factor ctaB [Mycobacterium tuberculosis
T17]
Length=269
Score = 530 bits (1365), Expect = 1e-148, Method: Compositional matrix adjust.
Identities = 268/269 (99%), Positives = 269/269 (100%), Gaps = 0/269 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
+NVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL
Sbjct 1 MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC
Sbjct 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL
Sbjct 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL
Sbjct 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAG 269
ALATSWLYGAVALVAGGWFLTMAHQLYAG
Sbjct 241 ALATSWLYGAVALVAGGWFLTMAHQLYAG 269
>gi|183982268|ref|YP_001850559.1| cytochrome C oxidase assembly factor CtaB [Mycobacterium marinum
M]
gi|183175594|gb|ACC40704.1| cytochrome C oxidase assembly factor CtaB [Mycobacterium marinum
M]
Length=324
Score = 499 bits (1286), Expect = 2e-139, Method: Compositional matrix adjust.
Identities = 260/322 (81%), Positives = 279/322 (87%), Gaps = 15/322 (4%)
Query 1 VNVRGRVAPRRVTG---------------RAMSTLLAYLALTKPRVIELLLVTAIPAMLL 45
++V GRVAP +V G R + T+LAYLALTKPRVIELLLVTAIPAMLL
Sbjct 1 MSVHGRVAPGQVAGTARQRSEPGTGTWRSRVLGTVLAYLALTKPRVIELLLVTAIPAMLL 60
Query 46 ADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALA 105
ADRGA+HPL++ NTL+GGMMAAAGANTLNCVADADIDKVMKRTARRPLAR AVPTR+AL
Sbjct 61 ADRGAVHPLIIANTLIGGMMAAAGANTLNCVADADIDKVMKRTARRPLARAAVPTRSALI 120
Query 106 LGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVM 165
GL LTVISFFWLW + NLL+G+LAL TVAFYVF+YTL LKRRTSQNVVWGGAAGCMPVM
Sbjct 121 FGLALTVISFFWLWLSANLLSGLLALATVAFYVFIYTLLLKRRTSQNVVWGGAAGCMPVM 180
Query 166 IGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQ 225
IGWSA+TGT+AWPALAMFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQ
Sbjct 181 IGWSAVTGTLAWPALAMFAIIFFWTPPHTWALAMRYKDDYKEAGVPMLPAVATERQVTKQ 240
Query 226 ILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQS 285
ILIYTWLTV ATL L A WLY AVA VAG WFLTMAHQLYAGVRAGE V+PLRLFLQS
Sbjct 241 ILIYTWLTVLATLALTPAAGWLYAAVAAVAGAWFLTMAHQLYAGVRAGEAVKPLRLFLQS 300
Query 286 NNYLAVVFCALAVDSVIALPTL 307
NNYLA+VFCALAVDS I LPTL
Sbjct 301 NNYLALVFCALAVDSAIGLPTL 322
>gi|254821677|ref|ZP_05226678.1| protoheme IX farnesyltransferase [Mycobacterium intracellulare
ATCC 13950]
Length=308
Score = 499 bits (1285), Expect = 2e-139, Method: Compositional matrix adjust.
Identities = 255/307 (84%), Positives = 274/307 (90%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VRGR AP R+ R T+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL
Sbjct 1 MSVRGRAAPSRLPSRVRGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AA GANTLNCVADADIDKVMKRTARRPLAR AVPTRNAL LGL LTV SFFWLW
Sbjct 61 IGGMLAAGGANTLNCVADADIDKVMKRTARRPLARAAVPTRNALVLGLVLTVGSFFWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL T+AFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+T TI WPAL
Sbjct 121 TTNLLSGLLALATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTNTIGWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQILIYTWLTV +TL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILIYTWLTVLSTLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA+VAG WFL MAHQLYAGVR GEPV+PLRLFLQSNNYLAVVFCALA+DS
Sbjct 241 ALATGWLYAAVAVVAGVWFLAMAHQLYAGVRVGEPVKPLRLFLQSNNYLAVVFCALAIDS 300
Query 301 VIALPTL 307
I LP L
Sbjct 301 AIGLPHL 307
>gi|118471528|ref|YP_887420.1| protoheme IX farnesyltransferase [Mycobacterium smegmatis str.
MC2 155]
gi|182639210|sp|A0QWY2.1|COXX_MYCS2 RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|118172815|gb|ABK73711.1| protoheme IX farnesyltransferase [Mycobacterium smegmatis str.
MC2 155]
Length=308
Score = 498 bits (1282), Expect = 4e-139, Method: Compositional matrix adjust.
Identities = 247/299 (83%), Positives = 268/299 (90%), Gaps = 4/299 (1%)
Query 9 PRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAA 68
PRR+ +T LAYLALTKPRVIELLLVT IPAMLLADRG + PLL+LNTLVGGM+AAA
Sbjct 13 PRRIR----TTFLAYLALTKPRVIELLLVTTIPAMLLADRGTVDPLLILNTLVGGMLAAA 68
Query 69 GANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGV 128
GANTLNCVADADIDKVMKRTARRPLAR VPTR+AL GL LTV SF WLW +TNLL+G+
Sbjct 69 GANTLNCVADADIDKVMKRTARRPLARATVPTRHALIFGLVLTVTSFCWLWLSTNLLSGL 128
Query 129 LALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFF 188
LA+ T+AFYVFVYT+ LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL MF IIFF
Sbjct 129 LAVATIAFYVFVYTMLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLIIFF 188
Query 189 WTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLY 248
WTPPHTWALAMRYK DY+ AGVPMLPAVATERQVT+QILIYTWLTV TLVLALAT WLY
Sbjct 189 WTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLVLALATGWLY 248
Query 249 GAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
GAVAL+AG WFL MAHQLY+GV+ GEPV+PLRLFLQSNNYLAVVFCALA+DS +ALPTL
Sbjct 249 GAVALLAGAWFLVMAHQLYSGVKRGEPVKPLRLFLQSNNYLAVVFCALAIDSALALPTL 307
>gi|118617455|ref|YP_905787.1| protoheme IX farnesyltransferase [Mycobacterium ulcerans Agy99]
gi|182639208|sp|A0PPP7.1|COXX_MYCUA RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|118569565|gb|ABL04316.1| cytochrome C oxidase assembly factor CtaB [Mycobacterium ulcerans
Agy99]
Length=324
Score = 498 bits (1281), Expect = 7e-139, Method: Compositional matrix adjust.
Identities = 259/322 (81%), Positives = 278/322 (87%), Gaps = 15/322 (4%)
Query 1 VNVRGRVAPRRVTG---------------RAMSTLLAYLALTKPRVIELLLVTAIPAMLL 45
++V GRVAP +V G R + T+LAYLALTKPRVIELLLVTAIPAMLL
Sbjct 1 MSVHGRVAPGQVAGTARQRSEPGTGTWRSRVLGTVLAYLALTKPRVIELLLVTAIPAMLL 60
Query 46 ADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALA 105
ADRGA+HPL++ NTL+GGMMAAAGANTLNCVADADIDKVM RTARRPLAR AVPTR+AL
Sbjct 61 ADRGAVHPLIIANTLIGGMMAAAGANTLNCVADADIDKVMNRTARRPLARAAVPTRSALI 120
Query 106 LGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVM 165
GL LTVISFFWLW + NLL+G+LAL TVAFYVF+YTL LKRRTSQNVVWGGAAGCMPVM
Sbjct 121 FGLALTVISFFWLWLSANLLSGLLALATVAFYVFIYTLLLKRRTSQNVVWGGAAGCMPVM 180
Query 166 IGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQ 225
IGWSA+TGT+AWPALAMFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQ
Sbjct 181 IGWSAVTGTLAWPALAMFAIIFFWTPPHTWALAMRYKDDYKEAGVPMLPAVATERQVTKQ 240
Query 226 ILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQS 285
ILIYTWLTV ATL L A WLY AVA VAG WFLTMAHQLYAGVRAGE V+PLRLFLQS
Sbjct 241 ILIYTWLTVLATLALTPAAGWLYAAVAAVAGAWFLTMAHQLYAGVRAGEAVKPLRLFLQS 300
Query 286 NNYLAVVFCALAVDSVIALPTL 307
NNYLA+VFCALAVDS I LPTL
Sbjct 301 NNYLALVFCALAVDSAIGLPTL 322
>gi|15827232|ref|NP_301495.1| protoheme IX farnesyltransferase [Mycobacterium leprae TN]
gi|221229710|ref|YP_002503126.1| protoheme IX farnesyltransferase [Mycobacterium leprae Br4923]
gi|13092781|emb|CAC30092.1| putative protoheme IX farnesyltransferase [Mycobacterium leprae]
gi|219932817|emb|CAR70677.1| putative protoheme IX farnesyltransferase [Mycobacterium leprae
Br4923]
Length=321
Score = 496 bits (1277), Expect = 2e-138, Method: Compositional matrix adjust.
Identities = 255/307 (84%), Positives = 271/307 (89%), Gaps = 8/307 (2%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
V+VR R+A RV LAYLALTKPRVIELLLVTAIPAMLLADRG+ +PLL+LNTL
Sbjct 22 VSVRARLARSRV--------LAYLALTKPRVIELLLVTAIPAMLLADRGSANPLLILNTL 73
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GG+ AAAGANT NCVADADIDK+MKRT+RRPLAR AVP RNAL LGL LT SFFWLW
Sbjct 74 LGGISAAAGANTFNCVADADIDKLMKRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWW 133
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL TVAFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSAIT TI WPAL
Sbjct 134 TTNLLSGLLALATVAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPAL 193
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYK DY+VA VPMLPAVATER VTKQILIYTWLT +TLVL
Sbjct 194 AMFAIIFFWTPPHTWALAMRYKDDYKVASVPMLPAVATERHVTKQILIYTWLTALSTLVL 253
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA+VAG WFLTMAHQLY GV AGEPV+PLRLFLQSNNYLAVVFCALAVDS
Sbjct 254 ALATGWLYMAVAVVAGAWFLTMAHQLYVGVCAGEPVKPLRLFLQSNNYLAVVFCALAVDS 313
Query 301 VIALPTL 307
V+ALPTL
Sbjct 314 VLALPTL 320
>gi|182639251|sp|Q9CCN4.2|COXX_MYCLE RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
Length=308
Score = 496 bits (1277), Expect = 2e-138, Method: Compositional matrix adjust.
Identities = 255/307 (84%), Positives = 271/307 (89%), Gaps = 8/307 (2%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
V+VR R+A RV LAYLALTKPRVIELLLVTAIPAMLLADRG+ +PLL+LNTL
Sbjct 9 VSVRARLARSRV--------LAYLALTKPRVIELLLVTAIPAMLLADRGSANPLLILNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GG+ AAAGANT NCVADADIDK+MKRT+RRPLAR AVP RNAL LGL LT SFFWLW
Sbjct 61 LGGISAAAGANTFNCVADADIDKLMKRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL TVAFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSAIT TI WPAL
Sbjct 121 TTNLLSGLLALATVAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYK DY+VA VPMLPAVATER VTKQILIYTWLT +TLVL
Sbjct 181 AMFAIIFFWTPPHTWALAMRYKDDYKVASVPMLPAVATERHVTKQILIYTWLTALSTLVL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA+VAG WFLTMAHQLY GV AGEPV+PLRLFLQSNNYLAVVFCALAVDS
Sbjct 241 ALATGWLYMAVAVVAGAWFLTMAHQLYVGVCAGEPVKPLRLFLQSNNYLAVVFCALAVDS 300
Query 301 VIALPTL 307
V+ALPTL
Sbjct 301 VLALPTL 307
>gi|342858743|ref|ZP_08715398.1| protoheme IX farnesyltransferase [Mycobacterium colombiense CECT
3035]
gi|342134447|gb|EGT87627.1| protoheme IX farnesyltransferase [Mycobacterium colombiense CECT
3035]
Length=308
Score = 494 bits (1273), Expect = 5e-138, Method: Compositional matrix adjust.
Identities = 257/307 (84%), Positives = 276/307 (90%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VRGRVAP ++ R T+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL
Sbjct 1 MSVRGRVAPSQMPSRIQGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AA GANTLNCVADADIDKVMKRTARRPLAR AVPTRNAL LGL LTV SF WLW
Sbjct 61 IGGMLAAGGANTLNCVADADIDKVMKRTARRPLARAAVPTRNALVLGLVLTVSSFVWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL T+AFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 121 TTNLLSGLLALATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQILIYTWLTV ATL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILIYTWLTVLATLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA++AG WFL MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALAVDS
Sbjct 241 ALATGWLYAAVAVLAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAVDS 300
Query 301 VIALPTL 307
I LP L
Sbjct 301 AIGLPHL 307
>gi|466878|gb|AAA17123.1| cyoE [Mycobacterium leprae]
Length=300
Score = 494 bits (1272), Expect = 8e-138, Method: Compositional matrix adjust.
Identities = 254/307 (83%), Positives = 271/307 (89%), Gaps = 8/307 (2%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VR R+A RV LAYLALTKPRVIELLLVTAIPAMLLADRG+ +PLL+LNTL
Sbjct 1 MSVRARLARSRV--------LAYLALTKPRVIELLLVTAIPAMLLADRGSANPLLILNTL 52
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GG+ AAAGANT NCVADADIDK+MKRT+RRPLAR AVP RNAL LGL LT SFFWLW
Sbjct 53 LGGISAAAGANTFNCVADADIDKLMKRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWW 112
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL TVAFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSAIT TI WPAL
Sbjct 113 TTNLLSGLLALATVAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPAL 172
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
AMFAIIFFWTPPHTWALAMRYK DY+VA VPMLPAVATER VTKQILIYTWLT +TLVL
Sbjct 173 AMFAIIFFWTPPHTWALAMRYKDDYKVASVPMLPAVATERHVTKQILIYTWLTALSTLVL 232
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA+VAG WFLTMAHQLY GV AGEPV+PLRLFLQSNNYLAVVFCALAVDS
Sbjct 233 ALATGWLYMAVAVVAGAWFLTMAHQLYVGVCAGEPVKPLRLFLQSNNYLAVVFCALAVDS 292
Query 301 VIALPTL 307
V+ALPTL
Sbjct 293 VLALPTL 299
>gi|2398716|emb|CAB16181.1| cytochrome c oxidase assembly factor [Mycobacterium leprae]
Length=289
Score = 491 bits (1264), Expect = 7e-137, Method: Compositional matrix adjust.
Identities = 248/288 (87%), Positives = 263/288 (92%), Gaps = 0/288 (0%)
Query 20 LLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADA 79
+LAYLALTKPRVIELLLVTAIPAMLLADRG+ +PLL+LNTL+GG+ AAAGANT NCVADA
Sbjct 1 MLAYLALTKPRVIELLLVTAIPAMLLADRGSANPLLILNTLLGGISAAAGANTFNCVADA 60
Query 80 DIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVF 139
DIDK+MKRT+RRPLAR AVP RNAL LGL LT SFFWLW TNLL+G+LAL TVAFYVF
Sbjct 61 DIDKLMKRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWWTTNLLSGLLALATVAFYVF 120
Query 140 VYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAM 199
VYTL LKRRTSQNVVWGGAAGCMPVMIGWSAIT TI WPALAMFAIIFFWTPPHTWALAM
Sbjct 121 VYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPALAMFAIIFFWTPPHTWALAM 180
Query 200 RYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWF 259
RYK DY+VA VPMLPAVATER VTKQILIYTWLT +TLVLALAT WLY AVA+VAG WF
Sbjct 181 RYKDDYKVASVPMLPAVATERHVTKQILIYTWLTALSTLVLALATGWLYMAVAVVAGAWF 240
Query 260 LTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
LTMAHQLY GV AGEPV+PLRLFLQSNNYLAVVFCALAVDSV+ALPTL
Sbjct 241 LTMAHQLYVGVCAGEPVKPLRLFLQSNNYLAVVFCALAVDSVLALPTL 288
>gi|254775771|ref|ZP_05217287.1| protoheme IX farnesyltransferase [Mycobacterium avium subsp.
avium ATCC 25291]
Length=308
Score = 488 bits (1257), Expect = 4e-136, Method: Compositional matrix adjust.
Identities = 254/307 (83%), Positives = 272/307 (89%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VRGRVAP + R T+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL
Sbjct 1 MSVRGRVAPSQTPSRIPGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AA GAN LNCVADADIDKVMKRTARRPLAR AVPTRNAL GL LT SF WLW
Sbjct 61 IGGMLAAGGANALNCVADADIDKVMKRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL T+AFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 121 TTNLLSGLLALATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQIL+YTWLTV ATL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILVYTWLTVLATLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVALVAG WFL MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALA+DS
Sbjct 241 ALATGWLYAAVALVAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAIDS 300
Query 301 VIALPTL 307
I LP L
Sbjct 301 AIGLPHL 307
>gi|41407277|ref|NP_960113.1| protoheme IX farnesyltransferase [Mycobacterium avium subsp.
paratuberculosis K-10]
gi|81414489|sp|Q741B3.1|COXX_MYCPA RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|41395629|gb|AAS03496.1| CtaB [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336458006|gb|EGO36993.1| protoheme IX farnesyltransferase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=308
Score = 487 bits (1254), Expect = 9e-136, Method: Compositional matrix adjust.
Identities = 252/307 (83%), Positives = 272/307 (89%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VRGRVAP + R T+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL
Sbjct 1 MSVRGRVAPSQTPSRIPGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AA GAN LNCVADADIDKVMKRTARRPLAR AVPTRNAL GL LT SF WLW
Sbjct 61 IGGMLAAGGANALNCVADADIDKVMKRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL T+AFYVF+YTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 121 TTNLLSGLLALATIAFYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQI++YTWLTV ATL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQIVVYTWLTVLATLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVALVAG WFL MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALA+DS
Sbjct 241 ALATGWLYAAVALVAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAIDS 300
Query 301 VIALPTL 307
I LP L
Sbjct 301 AIGLPHL 307
>gi|240171360|ref|ZP_04750019.1| protoheme IX farnesyltransferase [Mycobacterium kansasii ATCC
12478]
Length=288
Score = 484 bits (1245), Expect = 9e-135, Method: Compositional matrix adjust.
Identities = 246/287 (86%), Positives = 265/287 (93%), Gaps = 0/287 (0%)
Query 21 LAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADAD 80
+AYLALTKPRVIELLLVTAIPAMLLADRG++HPL++LNTL+GGMMAA GANTLNCVADAD
Sbjct 1 MAYLALTKPRVIELLLVTAIPAMLLADRGSVHPLVILNTLIGGMMAAGGANTLNCVADAD 60
Query 81 IDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFV 140
IDKVMKRTARRPLAR AVPTR+ALA GL LTV+S WLW TNLL+G+LAL TVAFYVFV
Sbjct 61 IDKVMKRTARRPLARAAVPTRSALAFGLALTVVSVLWLWWTTNLLSGLLALATVAFYVFV 120
Query 141 YTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMR 200
YTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGT+AWPALAMFAI+FFWTPPHTWALAMR
Sbjct 121 YTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTLAWPALAMFAIVFFWTPPHTWALAMR 180
Query 201 YKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFL 260
YK+DYQ AGVPMLPAVATERQVT+QILIYTWLTV ATL L AT WLY AVA+VAG WFL
Sbjct 181 YKEDYQEAGVPMLPAVATERQVTRQILIYTWLTVLATLALTPATGWLYAAVAVVAGAWFL 240
Query 261 TMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
MAHQL AGVRAGEPV+PLRLFLQSNNYLA+VFCALAVDS + LPTL
Sbjct 241 AMAHQLDAGVRAGEPVKPLRLFLQSNNYLALVFCALAVDSALGLPTL 287
>gi|182639259|sp|A0QHX0.2|COXX_MYCA1 RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
Length=308
Score = 475 bits (1222), Expect = 4e-132, Method: Compositional matrix adjust.
Identities = 252/307 (83%), Positives = 272/307 (89%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
++VRGRVAP + R T+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL
Sbjct 1 MSVRGRVAPSQTPSRIPGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AA GAN LNCVADADIDKVMKRTARRPLAR AVPTRNAL GL LT SF WLW
Sbjct 61 IGGMLAAGGANALNCVADADIDKVMKRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWW 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
TNLL+G+LAL T+AFYVF+YTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 121 TTNLLSGLLALATIAFYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVTKQIL+YTWLTV ATL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILVYTWLTVLATLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY AVA+VAG WFL MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALA+DS
Sbjct 241 ALATGWLYAAVAVVAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAIDS 300
Query 301 VIALPTL 307
I LP L
Sbjct 301 AIGLPHL 307
>gi|108799382|ref|YP_639579.1| protoheme IX farnesyltransferase [Mycobacterium sp. MCS]
gi|119868496|ref|YP_938448.1| protoheme IX farnesyltransferase [Mycobacterium sp. KMS]
gi|108769801|gb|ABG08523.1| protoheme IX farnesyltransferase [Mycobacterium sp. MCS]
gi|119694585|gb|ABL91658.1| protoheme IX farnesyltransferase [Mycobacterium sp. KMS]
Length=333
Score = 474 bits (1221), Expect = 6e-132, Method: Compositional matrix adjust.
Identities = 246/307 (81%), Positives = 271/307 (89%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
V++R R R +T+LAYLALTKPRVIELLLVTAIPAMLLADRG++ PLL+LNTL
Sbjct 24 VSIRERHLSHGAPSRIRTTVLAYLALTKPRVIELLLVTAIPAMLLADRGSVDPLLILNTL 83
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AAAGANTLNCVADADIDK MKRTARRPLAR+ VPTRNAL GL L+V SFFWLW
Sbjct 84 IGGMLAAAGANTLNCVADADIDKKMKRTARRPLARDTVPTRNALIFGLVLSVGSFFWLWG 143
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
+NLL+G+LA+ T+AFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 144 TSNLLSGLLAVATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 203
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVT+QILIYTWLTV TL L
Sbjct 204 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLAL 263
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY +VA++AG WFL MAHQLY GV+ GEPV+PLRLFLQSNNYLAVVF ALAVDS
Sbjct 264 ALATGWLYASVAVLAGTWFLVMAHQLYNGVKRGEPVKPLRLFLQSNNYLAVVFAALAVDS 323
Query 301 VIALPTL 307
V+ALPTL
Sbjct 324 VLALPTL 330
>gi|126435039|ref|YP_001070730.1| protoheme IX farnesyltransferase [Mycobacterium sp. JLS]
gi|182639211|sp|A3PZB2.1|COXX_MYCSJ RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|182639254|sp|A1UFQ0.2|COXX_MYCSK RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|182639255|sp|Q1B9B1.2|COXX_MYCSS RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|126234839|gb|ABN98239.1| protoheme IX farnesyltransferase [Mycobacterium sp. JLS]
Length=310
Score = 472 bits (1214), Expect = 4e-131, Method: Compositional matrix adjust.
Identities = 245/307 (80%), Positives = 271/307 (89%), Gaps = 0/307 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
+++R R R +T+LAYLALTKPRVIELLLVTAIPAMLLADRG++ PLL+LNTL
Sbjct 1 MSIRERHLSHGAPSRIRTTVLAYLALTKPRVIELLLVTAIPAMLLADRGSVDPLLILNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
+GGM+AAAGANTLNCVADADIDK MKRTARRPLAR+ VPTRNAL GL L+V SFFWLW
Sbjct 61 IGGMLAAAGANTLNCVADADIDKKMKRTARRPLARDTVPTRNALIFGLVLSVGSFFWLWG 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
+NLL+G+LA+ T+AFYVFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL
Sbjct 121 TSNLLSGLLAVATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL 240
MFAIIFFWTPPHTWALAMRYK DY+ AGVPMLPAVATERQVT+QILIYTWLTV TL L
Sbjct 181 VMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLAL 240
Query 241 ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS 300
ALAT WLY +VA++AG WFL MAHQLY GV+ GEPV+PLRLFLQSNNYLAVVF ALAVDS
Sbjct 241 ALATGWLYASVAVLAGTWFLVMAHQLYNGVKRGEPVKPLRLFLQSNNYLAVVFAALAVDS 300
Query 301 VIALPTL 307
V+ALPTL
Sbjct 301 VLALPTL 307
>gi|296170687|ref|ZP_06852262.1| protoheme IX farnesyltransferase [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295894676|gb|EFG74410.1| protoheme IX farnesyltransferase [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=293
Score = 470 bits (1209), Expect = 2e-130, Method: Compositional matrix adjust.
Identities = 247/290 (86%), Positives = 261/290 (90%), Gaps = 0/290 (0%)
Query 18 STLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVA 77
T+LAYLALTKPRVIELLLVT IPAMLLA RG + PLL+LNTL+GGM+AA GANTLNCVA
Sbjct 3 GTVLAYLALTKPRVIELLLVTTIPAMLLAHRGTVDPLLILNTLIGGMLAAGGANTLNCVA 62
Query 78 DADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFY 137
DADIDKVMKRTARRPLAR AVP +AL GL L+V SFFWLW TN+L+ LA T+AFY
Sbjct 63 DADIDKVMKRTARRPLARAAVPRSHALVFGLALSVASFFWLWWTTNMLSAHLAGATIAFY 122
Query 138 VFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWAL 197
VFVYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTIAWPAL MFAIIFFWTPPHTWAL
Sbjct 123 VFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIAWPALVMFAIIFFWTPPHTWAL 182
Query 198 AMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGG 257
AMRYK DY+ AGVPMLPA+ATERQVTKQILIYTWLTVAATL LALAT WLY AVALVAG
Sbjct 183 AMRYKDDYKAAGVPMLPAIATERQVTKQILIYTWLTVAATLALALATGWLYAAVALVAGV 242
Query 258 WFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
WFL MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALAVDSVIALP L
Sbjct 243 WFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAVDSVIALPHL 292
>gi|118462366|ref|YP_882508.1| protoheme IX farnesyltransferase [Mycobacterium avium 104]
gi|118163653|gb|ABK64550.1| protoheme IX farnesyltransferase [Mycobacterium avium 104]
Length=289
Score = 459 bits (1180), Expect = 4e-127, Method: Compositional matrix adjust.
Identities = 243/288 (85%), Positives = 260/288 (91%), Gaps = 0/288 (0%)
Query 20 LLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADA 79
+LAYLALTKPRVIELLLVTAIPAMLLA RG ++PLL++NTL+GGM+AA GAN LNCVADA
Sbjct 1 MLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTLIGGMLAAGGANALNCVADA 60
Query 80 DIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVF 139
DIDKVMKRTARRPLAR AVPTRNAL GL LT SF WLW TNLL+G+LAL T+AFYVF
Sbjct 61 DIDKVMKRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWWTTNLLSGLLALATIAFYVF 120
Query 140 VYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAM 199
+YTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL MFAIIFFWTPPHTWALAM
Sbjct 121 IYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAIIFFWTPPHTWALAM 180
Query 200 RYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWF 259
RYK DY+ AGVPMLPAVATERQVTKQIL+YTWLTV ATL LALAT WLY AVA+VAG WF
Sbjct 181 RYKDDYKAAGVPMLPAVATERQVTKQILVYTWLTVLATLALALATGWLYAAVAVVAGVWF 240
Query 260 LTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
L MAHQLYAGVRAGEPV+PLRLFLQSNNYLAVVFCALA+DS I LP L
Sbjct 241 LAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAIDSAIGLPHL 288
>gi|333990905|ref|YP_004523519.1| cytochrome C oxidase assembly factor CtaB [Mycobacterium sp.
JDM601]
gi|333486873|gb|AEF36265.1| cytochrome C oxidase assembly factor CtaB [Mycobacterium sp.
JDM601]
Length=293
Score = 456 bits (1174), Expect = 2e-126, Method: Compositional matrix adjust.
Identities = 222/290 (77%), Positives = 250/290 (87%), Gaps = 0/290 (0%)
Query 18 STLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVA 77
STLLAYL+LTKPR+IELLLVT IPAMLLADRG ++PLL+ NTL+GGM+AAAGA+ LNCV
Sbjct 3 STLLAYLSLTKPRIIELLLVTTIPAMLLADRGTVNPLLIFNTLIGGMLAAAGAHALNCVV 62
Query 78 DADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFY 137
DADIDKVMKRTARRPLAR+AVPTRNAL GL L +SF WLW TNL++G+LA+ T+AFY
Sbjct 63 DADIDKVMKRTARRPLARDAVPTRNALVFGLVLGAVSFVWLWRFTNLMSGLLAVATIAFY 122
Query 138 VFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWAL 197
V VY++ LKR TSQNVVWGGAAGCMPV+IGWSA+TGT+ W AL MFA+IFFWTPPHTWAL
Sbjct 123 VLVYSMLLKRHTSQNVVWGGAAGCMPVVIGWSAVTGTVGWQALVMFAVIFFWTPPHTWAL 182
Query 198 AMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGG 257
AMRYK DY AGVPMLP VA+ER VT +I++YTW TV ATL L A WLY +VA +AG
Sbjct 183 AMRYKDDYAAAGVPMLPVVASERVVTHRIVVYTWATVIATLALVPAAGWLYASVAFLAGV 242
Query 258 WFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
WFL MAHQLYAGVR GEPV+PLRLFLQSNNYLAVVFCALAVDS I LPTL
Sbjct 243 WFLAMAHQLYAGVRRGEPVKPLRLFLQSNNYLAVVFCALAVDSAIGLPTL 292
>gi|120403705|ref|YP_953534.1| protoheme IX farnesyltransferase [Mycobacterium vanbaalenii PYR-1]
gi|182639209|sp|A1T8M8.1|COXX_MYCVP RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|119956523|gb|ABM13528.1| protoheme IX farnesyltransferase [Mycobacterium vanbaalenii PYR-1]
Length=313
Score = 451 bits (1161), Expect = 5e-125, Method: Compositional matrix adjust.
Identities = 235/293 (81%), Positives = 254/293 (87%), Gaps = 0/293 (0%)
Query 15 RAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLN 74
R +L Y+ LTKPRVIELLLVT IPAMLLADRG + PLL+LNTLVGG++AAAGANTLN
Sbjct 18 RFRDRVLGYIGLTKPRVIELLLVTTIPAMLLADRGTVDPLLILNTLVGGLLAAAGANTLN 77
Query 75 CVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTV 134
CVADADIDK MKRT RR LAR VP +AL GL L+V+SFFWLW TN+L+ LA T+
Sbjct 78 CVADADIDKKMKRTERRALARATVPRSHALIFGLALSVLSFFWLWWTTNMLSAHLAGATI 137
Query 135 AFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHT 194
AFYV +YTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL MF IIFFWTPPHT
Sbjct 138 AFYVLIYTLVLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLIIFFWTPPHT 197
Query 195 WALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALV 254
WALAMRYK+DY+ AGVPMLP VATERQVTKQILIYTWLTVAATL LALAT WLY AVA+V
Sbjct 198 WALAMRYKEDYEAAGVPMLPVVATERQVTKQILIYTWLTVAATLALALATGWLYAAVAIV 257
Query 255 AGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
AG WFL MAHQLYAGVR GEPV+PLRLFLQSNNYLAVVFCALAVDS +ALPTL
Sbjct 258 AGTWFLAMAHQLYAGVRRGEPVKPLRLFLQSNNYLAVVFCALAVDSALALPTL 310
>gi|289750010|ref|ZP_06509388.1| cytochrome C oxidase assembly factor ctaB [Mycobacterium tuberculosis
T92]
gi|289690597|gb|EFD58026.1| cytochrome C oxidase assembly factor ctaB [Mycobacterium tuberculosis
T92]
Length=224
Score = 447 bits (1150), Expect = 9e-124, Method: Compositional matrix adjust.
Identities = 224/224 (100%), Positives = 224/224 (100%), Gaps = 0/224 (0%)
Query 85 MKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLW 144
MKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLW
Sbjct 1 MKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLW 60
Query 145 LKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQD 204
LKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQD
Sbjct 61 LKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQD 120
Query 205 YQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAH 264
YQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAH
Sbjct 121 YQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAH 180
Query 265 QLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
QLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
Sbjct 181 QLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 224
>gi|169629842|ref|YP_001703491.1| protoheme IX farnesyltransferase [Mycobacterium abscessus ATCC
19977]
gi|238688898|sp|B1MC66.1|COXX_MYCA9 RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|169241809|emb|CAM62837.1| Probable cytochrome c oxidase assembly factor CtaB [Mycobacterium
abscessus]
Length=313
Score = 446 bits (1148), Expect = 2e-123, Method: Compositional matrix adjust.
Identities = 228/304 (75%), Positives = 258/304 (85%), Gaps = 5/304 (1%)
Query 4 RGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGG 63
RGR AP + T+LAY+ALTKPRVIELLLVT IPAMLLADRG ++PLL+LNTL+GG
Sbjct 12 RGRNAPP-----FLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGG 66
Query 64 MMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATN 123
+MAAA ANTLNCVADADIDKVMKRTARRPLA +V TRNAL G+ L V +F WLW N
Sbjct 67 VMAAASANTLNCVADADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTAN 126
Query 124 LLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMF 183
LL+G+LA+ T+AFYVFVYTL LKRRT+QNVVWGGAAGCMPVMIGWSA+T TI WPAL MF
Sbjct 127 LLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQWPALVMF 186
Query 184 AIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALA 243
A+IFFWTPPHTWALAMRYK+DY+ AGVPMLP +ATE +VTK IL+YTWLTV +TL LALA
Sbjct 187 AVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLSTLALALA 246
Query 244 TSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIA 303
+Y VA +AG WFL MAHQLY+GVR G+P+RPLRLFLQSNNYLAVVFCALAVDSV+
Sbjct 247 AGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALAVDSVVG 306
Query 304 LPTL 307
PTL
Sbjct 307 WPTL 310
>gi|145224275|ref|YP_001134953.1| protoheme IX farnesyltransferase [Mycobacterium gilvum PYR-GCK]
gi|315444607|ref|YP_004077486.1| protoheme IX farnesyltransferase [Mycobacterium sp. Spyr1]
gi|205693456|sp|A4TC38.1|COXX_MYCGI RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|145216761|gb|ABP46165.1| protoheme IX farnesyltransferase [Mycobacterium gilvum PYR-GCK]
gi|315262910|gb|ADT99651.1| protoheme IX farnesyltransferase [Mycobacterium sp. Spyr1]
Length=313
Score = 443 bits (1139), Expect = 2e-122, Method: Compositional matrix adjust.
Identities = 226/290 (78%), Positives = 250/290 (87%), Gaps = 0/290 (0%)
Query 18 STLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVA 77
+ L+ Y+ LTKPRVIELLLVT IPAMLLADRG + PLL++NTLVGG++AAAGANTLNCVA
Sbjct 21 TRLMGYIGLTKPRVIELLLVTTIPAMLLADRGTVDPLLIINTLVGGLLAAAGANTLNCVA 80
Query 78 DADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFY 137
DADIDK MKRT RR LAR VP +AL GLTL+V SFFWLW TN+L+ LA T+AFY
Sbjct 81 DADIDKKMKRTERRALARATVPRSHALIFGLTLSVASFFWLWSTTNMLSAHLAGATIAFY 140
Query 138 VFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWAL 197
V VYTL LKRRTSQNVVWGGAAGCMPVMIGWSA+TGTI WPAL MF IIFFWTPPHTWAL
Sbjct 141 VLVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLIIFFWTPPHTWAL 200
Query 198 AMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGG 257
AMRYK+DY+ AGVPMLP VATE+QVTKQIL+YTWLTV ATL LAL T WLY +VA++AG
Sbjct 201 AMRYKEDYEAAGVPMLPVVATEQQVTKQILVYTWLTVLATLALALTTGWLYASVAILAGT 260
Query 258 WFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
WFL MAHQLYAGV+ GE V+PLRLFLQSNNYLAVVF ALAVDS +ALPTL
Sbjct 261 WFLVMAHQLYAGVKRGEAVKPLRLFLQSNNYLAVVFVALAVDSALALPTL 310
>gi|289745200|ref|ZP_06504578.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
02_1987]
gi|289685728|gb|EFD53216.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
02_1987]
Length=221
Score = 439 bits (1129), Expect = 3e-121, Method: Compositional matrix adjust.
Identities = 220/221 (99%), Positives = 221/221 (100%), Gaps = 0/221 (0%)
Query 1 VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
+NVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL
Sbjct 1 MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL 60
Query 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC
Sbjct 61 VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC 120
Query 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL
Sbjct 121 ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL 180
Query 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQ 221
AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQ
Sbjct 181 AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQ 221
>gi|54025542|ref|YP_119784.1| protoheme IX farnesyltransferase [Nocardia farcinica IFM 10152]
gi|81374339|sp|Q5YTS1.1|COXX_NOCFA RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
gi|54017050|dbj|BAD58420.1| putative protoheme IX farnesyltransferase [Nocardia farcinica
IFM 10152]
Length=311
Score = 437 bits (1125), Expect = 8e-121, Method: Compositional matrix adjust.
Identities = 219/293 (75%), Positives = 241/293 (83%), Gaps = 0/293 (0%)
Query 15 RAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLN 74
R M +LAY+ALTKPRVIELLLV IP MLLADRG I L+L TL GG M AA ANTLN
Sbjct 14 RLMRRVLAYIALTKPRVIELLLVATIPTMLLADRGHIDIRLILATLFGGWMGAASANTLN 73
Query 75 CVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTV 134
CVADADIDKVMKRTA+RPLAR+AVPTRNA G+ L + SF WLW NLL+G L + T+
Sbjct 74 CVADADIDKVMKRTAKRPLARDAVPTRNAFVFGVVLGLASFAWLWWQANLLSGALVVATI 133
Query 135 AFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHT 194
FYVFVYTL LKRRTSQNVVWGGAAGCMP ++GWSA+TGTI WPALA+F +IFFWTPPHT
Sbjct 134 LFYVFVYTLGLKRRTSQNVVWGGAAGCMPALVGWSAVTGTIGWPALALFGVIFFWTPPHT 193
Query 195 WALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALV 254
WALAMRYK+DY+ AGVPMLP VATER VTKQI+IYTWLTV TL L AT +Y AVALV
Sbjct 194 WALAMRYKEDYRAAGVPMLPVVATERTVTKQIVIYTWLTVLTTLALVPATGVIYAAVALV 253
Query 255 AGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
AG WFL MAHQLYAGVR GE V+PLRLFLQSNNYLAVVFC LAVDSV+ T+
Sbjct 254 AGAWFLLMAHQLYAGVRRGESVKPLRLFLQSNNYLAVVFCGLAVDSVLGWDTI 306
>gi|333919564|ref|YP_004493145.1| protoheme IX farnesyltransferase [Amycolicicoccus subflavus DQS3-9A1]
gi|333481785|gb|AEF40345.1| Protoheme IX farnesyltransferase [Amycolicicoccus subflavus DQS3-9A1]
Length=306
Score = 421 bits (1082), Expect = 8e-116, Method: Compositional matrix adjust.
Identities = 206/288 (72%), Positives = 240/288 (84%), Gaps = 0/288 (0%)
Query 20 LLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADA 79
++AY+ALTKPRVIELLLVT IPAMLLA RG + PLL+L TL GG MAAA AN+LNCV DA
Sbjct 13 IMAYIALTKPRVIELLLVTTIPAMLLASRGTVDPLLILATLFGGAMAAASANSLNCVVDA 72
Query 80 DIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVF 139
DIDKVMKRTARRPLAREAVPT +AL GL L V+SF W W ATNLLA LA+VT+ FY+F
Sbjct 73 DIDKVMKRTARRPLAREAVPTSHALVFGLVLGVLSFTWFWWATNLLAASLAVVTILFYIF 132
Query 140 VYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAM 199
VYTL LKRRTSQN+VWGGAAGCMPVMIGW+A TGT+ WPAL MF I+FFWTPPHTWALAM
Sbjct 133 VYTLVLKRRTSQNIVWGGAAGCMPVMIGWAATTGTLEWPALVMFLIVFFWTPPHTWALAM 192
Query 200 RYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWF 259
RYK+DY+ AGVPMLP V +E++VTK+I+IYTW+TV TL LA T +Y +AL+ G WF
Sbjct 193 RYKEDYRAAGVPMLPVVMSEQEVTKRIVIYTWVTVLTTLALAWWTGVIYALIALLVGIWF 252
Query 260 LTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
+ MA +LY+GV+AG PV+PLRLFL SNNYLA VFC LAVDS++ T+
Sbjct 253 VVMAQRLYSGVKAGVPVKPLRLFLMSNNYLAAVFCGLAVDSILGFATV 300
>gi|226306533|ref|YP_002766493.1| protoheme IX farnesyltransferase [Rhodococcus erythropolis PR4]
gi|226185650|dbj|BAH33754.1| putative protoheme IX farnesyltransferase [Rhodococcus erythropolis
PR4]
Length=301
Score = 417 bits (1073), Expect = 9e-115, Method: Compositional matrix adjust.
Identities = 201/295 (69%), Positives = 238/295 (81%), Gaps = 0/295 (0%)
Query 14 GRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTL 73
GRA +LAY+ALTKPRVIELLLV IPAMLLADRG + +L+L+TL GG M AA AN+L
Sbjct 3 GRATGKVLAYIALTKPRVIELLLVATIPAMLLADRGTVDIVLILSTLFGGWMGAASANSL 62
Query 74 NCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVT 133
NCV DADIDKVMKRTA+RPLAREAVPTRNAL GL L + SF WLW NLLAG+L ++T
Sbjct 63 NCVVDADIDKVMKRTAKRPLAREAVPTRNALVFGLLLGLASFLWLWWRANLLAGILVVIT 122
Query 134 VAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPH 193
+AFYV +YT+ LKRRT QNV+WGGAAGCMPV++GW+A+TG+++W + +F IIFFWTPPH
Sbjct 123 IAFYVLIYTMVLKRRTWQNVIWGGAAGCMPVLVGWAAVTGSLSWQPVVLFLIIFFWTPPH 182
Query 194 TWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVAL 253
TWALAMRYK+DY+ AGVPMLP +ATE VTKQIL Y+W V TLVL A+ +Y A+ +
Sbjct 183 TWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILFYSWAMVVTTLVLVPASGVIYAAITI 242
Query 254 VAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
VAG WFL MAHQLY VR G V+PLRLFLQSNNYLA+VF LAVDSV+ L T+
Sbjct 243 VAGAWFLLMAHQLYRSVRGGAQVKPLRLFLQSNNYLAIVFVGLAVDSVLGLQTIS 297
>gi|229493657|ref|ZP_04387442.1| protoheme IX farnesyltransferase [Rhodococcus erythropolis SK121]
gi|229319618|gb|EEN85454.1| protoheme IX farnesyltransferase [Rhodococcus erythropolis SK121]
Length=327
Score = 416 bits (1070), Expect = 2e-114, Method: Compositional matrix adjust.
Identities = 202/296 (69%), Positives = 239/296 (81%), Gaps = 0/296 (0%)
Query 12 VTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN 71
V GRA +LAY+ALTKPRVIELLLV IPAMLLADRG + +L+L+TL GG M AA AN
Sbjct 27 VWGRATGKVLAYIALTKPRVIELLLVATIPAMLLADRGTVDIVLILSTLFGGWMGAASAN 86
Query 72 TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL 131
+LNCV DADIDKVMKRTA+RPLAREAVPTRNAL GL L + SF WLW NLLAG+L +
Sbjct 87 SLNCVVDADIDKVMKRTAKRPLAREAVPTRNALVFGLLLGLASFLWLWWRANLLAGILVV 146
Query 132 VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP 191
+T+AFYV +YT+ LKRRT QNV+WGGAAGCMPV++GW+A+TG+++W + +F IIFFWTP
Sbjct 147 ITIAFYVLIYTMVLKRRTWQNVIWGGAAGCMPVLVGWAAVTGSLSWQPVVLFLIIFFWTP 206
Query 192 PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV 251
PHTWALAMRYK+DY+ AGVPMLP +ATE VTKQIL Y+W V TLVL A+ +Y A+
Sbjct 207 PHTWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILFYSWAMVVTTLVLVPASGVIYAAI 266
Query 252 ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
+VAG WFL MAHQLY VR G V+PLRLFLQSNNYLA+VF LAVDSV+ L T+
Sbjct 267 TIVAGAWFLLMAHQLYRSVRGGAQVKPLRLFLQSNNYLAIVFVGLAVDSVLGLQTI 322
>gi|226366377|ref|YP_002784160.1| protoheme IX farnesyltransferase [Rhodococcus opacus B4]
gi|226244867|dbj|BAH55215.1| putative protoheme IX farnesyltransferase [Rhodococcus opacus
B4]
Length=327
Score = 413 bits (1061), Expect = 2e-113, Method: Compositional matrix adjust.
Identities = 204/296 (69%), Positives = 236/296 (80%), Gaps = 0/296 (0%)
Query 12 VTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN 71
V GR +LAY+ALTKPRVIELLLV IPAMLLADRG + LL+L+TL GG M AA AN
Sbjct 27 VLGRVTGKVLAYIALTKPRVIELLLVATIPAMLLADRGNVDILLILSTLFGGWMGAASAN 86
Query 72 TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL 131
+LNCV DADIDKVMKRTARRPLAR+AVPT +A G+TL V SF WLW NLLAG L +
Sbjct 87 SLNCVVDADIDKVMKRTARRPLARDAVPTSHAFVFGMTLGVASFLWLWWRANLLAGCLVV 146
Query 132 VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP 191
+T+AFYV VYT+ LKRRT QNVVWGGAAGCMPVM+GWSA+TG+++W + +F +IFFWTP
Sbjct 147 LTIAFYVLVYTMVLKRRTWQNVVWGGAAGCMPVMVGWSAVTGSLSWQPIVLFLVIFFWTP 206
Query 192 PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV 251
PHTWALAMRYK+DY+ AGVPMLP +ATE VTKQIL+Y+W V +LVL A +Y AV
Sbjct 207 PHTWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILLYSWAMVITSLVLVPAAGVVYAAV 266
Query 252 ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
LVAG WFL MAHQLY VR G V+PLRLFLQSNNYLA+VF LAVDSV+ L T+
Sbjct 267 TLVAGAWFLLMAHQLYRSVRGGAAVKPLRLFLQSNNYLAIVFVGLAVDSVLGLQTI 322
>gi|312139618|ref|YP_004006954.1| protoheme ix farnesyltransferase cyoe [Rhodococcus equi 103S]
gi|325676706|ref|ZP_08156380.1| protoheme IX farnesyltransferase [Rhodococcus equi ATCC 33707]
gi|311888957|emb|CBH48270.1| protoheme IX farnesyltransferase CyoE [Rhodococcus equi 103S]
gi|325552488|gb|EGD22176.1| protoheme IX farnesyltransferase [Rhodococcus equi ATCC 33707]
Length=329
Score = 411 bits (1056), Expect = 7e-113, Method: Compositional matrix adjust.
Identities = 200/294 (69%), Positives = 238/294 (81%), Gaps = 0/294 (0%)
Query 14 GRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTL 73
GR +T+LAY+ALTKPRVIELLLV IPAMLLADRG I +L+L+TL GG M AA AN+L
Sbjct 32 GRVTATILAYVALTKPRVIELLLVATIPAMLLADRGHIDLVLILSTLFGGWMGAASANSL 91
Query 74 NCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVT 133
NCV DADIDKVMKRTA RPLAR+AVPT++A G+TL V SF WLW NLLAG L ++T
Sbjct 92 NCVVDADIDKVMKRTALRPLARQAVPTKHAFVFGMTLGVASFVWLWWRANLLAGFLVVLT 151
Query 134 VAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPH 193
+AFYV VYT+ LKRRT QNV+WGGAAGCMPVM+GW+A+TG+++W + +F IIFFWTPPH
Sbjct 152 IAFYVLVYTMVLKRRTWQNVIWGGAAGCMPVMVGWAAVTGSLSWEPVVLFLIIFFWTPPH 211
Query 194 TWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVAL 253
TWALAMRYK+DY+ AGVPMLP +A+E VTKQI+IYTW TV A+L L A W+Y V L
Sbjct 212 TWALAMRYKEDYKAAGVPMLPVIASETHVTKQIVIYTWATVLASLALVPAAGWIYAIVTL 271
Query 254 VAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
+AG WFL +AHQLY VR G P++PL+LFLQSNNYLAVV C LAVDSV+ T+
Sbjct 272 LAGAWFLFVAHQLYNSVRGGTPIKPLKLFLQSNNYLAVVCCGLAVDSVLGWDTI 325
>gi|182639245|sp|Q0S0I5.2|COXX_RHOSR RecName: Full=Protoheme IX farnesyltransferase; AltName: Full=Heme
B farnesyltransferase; AltName: Full=Heme O synthase
Length=301
Score = 410 bits (1053), Expect = 2e-112, Method: Compositional matrix adjust.
Identities = 202/294 (69%), Positives = 233/294 (80%), Gaps = 0/294 (0%)
Query 14 GRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTL 73
GR +LAY+ALTKPRVIELLLV IPAMLLADRG + L+L+TL GG M AA AN+L
Sbjct 3 GRVTGKVLAYIALTKPRVIELLLVATIPAMLLADRGNVDIALILSTLFGGWMGAASANSL 62
Query 74 NCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVT 133
NCV DADIDKVMKRTARRPLAR+AVPT +A G+TL V SF WLW NLLAG L ++T
Sbjct 63 NCVVDADIDKVMKRTARRPLARDAVPTSHAFVFGMTLGVASFLWLWWRANLLAGCLVVLT 122
Query 134 VAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPH 193
+AFYV VYT+ LKRRT QNVVWGGAAGCMPVM+GWSA+TG+++W + +F +IFFWTPPH
Sbjct 123 IAFYVLVYTMVLKRRTWQNVVWGGAAGCMPVMVGWSAVTGSLSWQPIVLFLVIFFWTPPH 182
Query 194 TWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVAL 253
TWALAMRYK+DY+ AGVPMLP +ATE VTKQIL+Y+W V +L L A +Y AV L
Sbjct 183 TWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILLYSWAMVITSLTLVPAAGVVYAAVTL 242
Query 254 VAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
VAG WFL MAHQLY VR G V+PLRLFLQSNNYLAVVF LAVDSV+ L T+
Sbjct 243 VAGAWFLLMAHQLYRSVRGGAAVKPLRLFLQSNNYLAVVFVGLAVDSVLGLQTV 296
>gi|111024137|ref|YP_707109.1| protoheme IX farnesyltransferase [Rhodococcus jostii RHA1]
gi|110823667|gb|ABG98951.1| probable protoheme IX farnesyltransferase [Rhodococcus jostii
RHA1]
Length=327
Score = 409 bits (1052), Expect = 2e-112, Method: Compositional matrix adjust.
Identities = 203/296 (69%), Positives = 234/296 (80%), Gaps = 0/296 (0%)
Query 12 VTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGAN 71
V GR +LAY+ALTKPRVIELLLV IPAMLLADRG + L+L+TL GG M AA AN
Sbjct 27 VLGRVTGKVLAYIALTKPRVIELLLVATIPAMLLADRGNVDIALILSTLFGGWMGAASAN 86
Query 72 TLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLAL 131
+LNCV DADIDKVMKRTARRPLAR+AVPT +A G+TL V SF WLW NLLAG L +
Sbjct 87 SLNCVVDADIDKVMKRTARRPLARDAVPTSHAFVFGMTLGVASFLWLWWRANLLAGCLVV 146
Query 132 VTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTP 191
+T+AFYV VYT+ LKRRT QNVVWGGAAGCMPVM+GWSA+TG+++W + +F +IFFWTP
Sbjct 147 LTIAFYVLVYTMVLKRRTWQNVVWGGAAGCMPVMVGWSAVTGSLSWQPIVLFLVIFFWTP 206
Query 192 PHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAV 251
PHTWALAMRYK+DY+ AGVPMLP +ATE VTKQIL+Y+W V +L L A +Y AV
Sbjct 207 PHTWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILLYSWAMVITSLTLVPAAGVVYAAV 266
Query 252 ALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
LVAG WFL MAHQLY VR G V+PLRLFLQSNNYLAVVF LAVDSV+ L T+
Sbjct 267 TLVAGAWFLLMAHQLYRSVRGGAAVKPLRLFLQSNNYLAVVFVGLAVDSVLGLQTV 322
>gi|296140221|ref|YP_003647464.1| protoheme IX farnesyltransferase [Tsukamurella paurometabola
DSM 20162]
gi|296028355|gb|ADG79125.1| protoheme IX farnesyltransferase [Tsukamurella paurometabola
DSM 20162]
Length=328
Score = 385 bits (988), Expect = 7e-105, Method: Compositional matrix adjust.
Identities = 191/299 (64%), Positives = 233/299 (78%), Gaps = 0/299 (0%)
Query 9 PRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAA 68
P+ GRA+ T+LAY+ALTKP+VIELLLV IP MLLADRG ++ L+L+TL GG + AA
Sbjct 24 PKTFAGRALQTVLAYIALTKPKVIELLLVATIPVMLLADRGHVNLGLILSTLFGGWLGAA 83
Query 69 GANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGV 128
ANTLN VADADIDK MKRT RRPLAR+AVPTR+AL G+ L SF WL TNLLA
Sbjct 84 SANTLNMVADADIDKKMKRTERRPLARQAVPTRHALIFGIALAAASFAWLSLTTNLLAAS 143
Query 129 LALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFF 188
L LVT+AFY+FVYT+ LKRRTSQNVVWGGAAGCMP ++GW+A TGTI WPA+ +F +IFF
Sbjct 144 LVLVTIAFYLFVYTMLLKRRTSQNVVWGGAAGCMPTLVGWAAATGTIQWPAIVLFLVIFF 203
Query 189 WTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLY 248
WTPPHTWALAMRY++DY+ AGVPMLP VA E V +Q++ YTW TV TLVL A +Y
Sbjct 204 WTPPHTWALAMRYREDYKAAGVPMLPVVAPETTVARQMVWYTWATVITTLVLIPAAGVVY 263
Query 249 GAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
A + G WFL H+LY +AG+ ++PL++FLQSNNYLAV+FCAL+VDS++ PT+
Sbjct 264 AVAAALCGAWFLYAVHKLYNQTKAGQEIKPLKVFLQSNNYLAVLFCALSVDSILNYPTV 322
>gi|257055629|ref|YP_003133461.1| protoheme IX farnesyltransferase [Saccharomonospora viridis DSM
43017]
gi|256585501|gb|ACU96634.1| protoheme IX farnesyltransferase [Saccharomonospora viridis DSM
43017]
Length=326
Score = 383 bits (984), Expect = 2e-104, Method: Compositional matrix adjust.
Identities = 196/303 (65%), Positives = 225/303 (75%), Gaps = 7/303 (2%)
Query 5 GRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGM 64
GR R V G AY AL KPRVIELLLVT IPAM LA R P L+L TLVGG
Sbjct 27 GRRGLREVIG-------AYAALAKPRVIELLLVTTIPAMFLAGREIPSPWLVLATLVGGT 79
Query 65 MAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNL 124
MAA AN LNCV DADIDKVM RT RRPL R++VP RNAL G+ L +ISF L+ NL
Sbjct 80 MAAGSANALNCVIDADIDKVMNRTRRRPLVRDSVPRRNALVFGIALGLISFGLLYVTVNL 139
Query 125 LAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFA 184
LA VLA+ T+ FY+FVYTL LKRRT QNVVWGGAAGCMPV+IGW+A+TGT+ WPA MF
Sbjct 140 LAAVLAVATILFYIFVYTLLLKRRTPQNVVWGGAAGCMPVVIGWAAVTGTVEWPAFVMFG 199
Query 185 IIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALAT 244
+IFFWTPPHTWALAMRY++DY+ AGVPMLP VAT + V KQI++Y+W+ VA TL+L AT
Sbjct 200 VIFFWTPPHTWALAMRYREDYERAGVPMLPVVATPKHVAKQIVVYSWVMVAWTLLLVPAT 259
Query 245 SWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIAL 304
SWLY A AL+AG WFL AH+LYA V GE +P+ LF +SN YL VVF ALAVD+ I L
Sbjct 260 SWLYAAFALLAGAWFLFYAHRLYASVARGEKTKPMALFHRSNTYLMVVFVALAVDAAIGL 319
Query 305 PTL 307
P
Sbjct 320 PVF 322
>gi|300784716|ref|YP_003765007.1| protoheme IX farnesyltransferase [Amycolatopsis mediterranei
U32]
gi|299794230|gb|ADJ44605.1| protoheme IX farnesyltransferase [Amycolatopsis mediterranei
U32]
gi|340526139|gb|AEK41344.1| protoheme IX farnesyltransferase [Amycolatopsis mediterranei
S699]
Length=326
Score = 376 bits (966), Expect = 2e-102, Method: Compositional matrix adjust.
Identities = 191/302 (64%), Positives = 223/302 (74%), Gaps = 7/302 (2%)
Query 6 RVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMM 65
R + RRV G AY AL KPRVIELLLVT IPAM LA R P L+L TLVGG M
Sbjct 28 RRSIRRVVG-------AYAALAKPRVIELLLVTTIPAMFLAGRQIPSPWLVLATLVGGTM 80
Query 66 AAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLL 125
AA AN LNCV DADIDKVM RT RRPL +++VP R AL GL + V S L+ NLL
Sbjct 81 AAGSANALNCVIDADIDKVMNRTKRRPLVKDSVPRRGALIFGLVMGVASAVVLYLTVNLL 140
Query 126 AGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAI 185
+ +LA+ T+ FY+FVYTL LKRRTSQNVVWGGAAGCMPV+IGW+A+TGT+ WPA MF +
Sbjct 141 SAILAIATILFYIFVYTLGLKRRTSQNVVWGGAAGCMPVVIGWAAVTGTVQWPAFVMFGV 200
Query 186 IFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATS 245
IFFWTPPHTWAL M+Y+ DY+ AGVPMLP VAT + V +QI+IY+W+ VA TL+L TS
Sbjct 201 IFFWTPPHTWALGMKYRDDYERAGVPMLPVVATAQHVARQIVIYSWVMVAWTLLLLPVTS 260
Query 246 WLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALP 305
WLYG A++AGGWFL AH L A VR GE +P+ LF +SN YL +VF ALAVDS I LP
Sbjct 261 WLYGTFAILAGGWFLFYAHSLQAAVRRGEETKPMALFHRSNTYLMIVFVALAVDSAIGLP 320
Query 306 TL 307
TL
Sbjct 321 TL 322
>gi|262202302|ref|YP_003273510.1| protoheme IX farnesyltransferase [Gordonia bronchialis DSM 43247]
gi|262085649|gb|ACY21617.1| protoheme IX farnesyltransferase [Gordonia bronchialis DSM 43247]
Length=335
Score = 373 bits (958), Expect = 2e-101, Method: Compositional matrix adjust.
Identities = 187/300 (63%), Positives = 229/300 (77%), Gaps = 1/300 (0%)
Query 8 APRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAA 67
AP R+ R T+LAY+ALTKPRVIELLLV IP ML ADRG + L++ TLVGG + A
Sbjct 33 APSRLR-RIQLTILAYIALTKPRVIELLLVATIPVMLQADRGHVDLLVIACTLVGGWLGA 91
Query 68 AGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAG 127
A ANTLN V DADID+ MKRTARRPLAR AV R+AL G+ L SF L A NLL+
Sbjct 92 ASANTLNMVVDADIDQKMKRTARRPLARRAVAPRSALVFGIVLWAASFAVLTVAANLLSA 151
Query 128 VLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIF 187
+L T+ FYV VYT+ LKRRT QNVVWGGAAGCMP ++GW+A+TG+++W + +F +IF
Sbjct 152 LLVSATIVFYVGVYTMILKRRTWQNVVWGGAAGCMPTLVGWAAVTGSLSWEPVVLFGVIF 211
Query 188 FWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWL 247
FWTPPHTWALAMRYK+DY+ AGVPMLP +ATE +VT+Q++IYTWLTV +L+L ATSW+
Sbjct 212 FWTPPHTWALAMRYKEDYKAAGVPMLPVIATEERVTRQMVIYTWLTVVCSLILVPATSWI 271
Query 248 YGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
Y AVA++AG WF + H LY R G V PL++FLQSN YLAV+FC LAVD+VI LPT+
Sbjct 272 YAAVAVLAGAWFASRVHILYRDTRRGAEVAPLKIFLQSNEYLAVLFCGLAVDAVIGLPTI 331
>gi|302525916|ref|ZP_07278258.1| protoheme IX farnesyltransferase [Streptomyces sp. AA4]
gi|302434811|gb|EFL06627.1| protoheme IX farnesyltransferase [Streptomyces sp. AA4]
Length=324
Score = 373 bits (957), Expect = 2e-101, Method: Compositional matrix adjust.
Identities = 185/286 (65%), Positives = 216/286 (76%), Gaps = 0/286 (0%)
Query 22 AYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADI 81
AY AL KPRVIELLLVT IPAM LA R +P L++ TL+GG MAA AN LNCV D+DI
Sbjct 35 AYAALAKPRVIELLLVTTIPAMFLAGREVPNPWLVVATLIGGTMAAGSANALNCVIDSDI 94
Query 82 DKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVY 141
DKVM RT RRPL ++AVP RNAL GL L + SF L+ NLLA VLA+ T+ FY+FVY
Sbjct 95 DKVMNRTKRRPLVKDAVPRRNALIFGLVLGLASFAVLYFTVNLLAAVLAIATILFYIFVY 154
Query 142 TLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRY 201
TL LKRRTSQNVVWGGAAGCMPV+IGW A+TGT+ WPA MF +IFFWTPPHTWAL M+Y
Sbjct 155 TLGLKRRTSQNVVWGGAAGCMPVLIGWVAVTGTVQWPAFVMFGVIFFWTPPHTWALGMKY 214
Query 202 KQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLT 261
+ DY+ AGVPMLP VAT V +QI+IY+W+ VA TL+L TSWLY A++AGGWFL
Sbjct 215 RDDYERAGVPMLPVVATAEHVARQIVIYSWVMVAWTLLLLPVTSWLYATFAILAGGWFLF 274
Query 262 MAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
AH+L A V GE +P+ LF +SN YL +VF ALAVDS I LP L
Sbjct 275 YAHRLQAAVHRGEETKPMALFHRSNTYLMIVFVALAVDSAIGLPVL 320
>gi|134098731|ref|YP_001104392.1| protoheme IX farnesyltransferase [Saccharopolyspora erythraea
NRRL 2338]
gi|291003584|ref|ZP_06561557.1| protoheme IX farnesyltransferase [Saccharopolyspora erythraea
NRRL 2338]
gi|182637465|sp|A4FBP2.1|COXX2_SACEN RecName: Full=Protoheme IX farnesyltransferase 2; AltName: Full=Heme
B farnesyltransferase 2; AltName: Full=Heme O synthase
2
gi|133911354|emb|CAM01467.1| protoheme IX farnesyltransferase [Saccharopolyspora erythraea
NRRL 2338]
Length=324
Score = 372 bits (956), Expect = 3e-101, Method: Compositional matrix adjust.
Identities = 190/301 (64%), Positives = 224/301 (75%), Gaps = 1/301 (0%)
Query 8 APR-RVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMA 66
AP+ R R L AY L KPRVIELLLVT IPAMLLA RG P L++ TLVGG MA
Sbjct 20 APQARHARRPAELLKAYAGLIKPRVIELLLVTTIPAMLLAARGIPSPWLVIATLVGGTMA 79
Query 67 AAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLA 126
A AN LNCVADADID+VMKRT RPL R V R+AL G+ L SF WLW TNLL+
Sbjct 80 AGSANALNCVADADIDQVMKRTRARPLVRHTVSNRHALVFGIALGAGSFGWLWATTNLLS 139
Query 127 GVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAII 186
VLA+ T+ FYVFVYTL LKRRT+QN+VWGGAAGCMPV+IGW+ +TG + WPAL MF II
Sbjct 140 AVLAVATILFYVFVYTLVLKRRTAQNIVWGGAAGCMPVVIGWAGVTGRVDWPALVMFGII 199
Query 187 FFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSW 246
FFWTPPHTW+LAM+Y+ DY+ AGVPMLP VA V++QI+++TWL V TL+LA AT W
Sbjct 200 FFWTPPHTWSLAMKYRDDYERAGVPMLPVVARPTYVSRQIVVFTWLMVLWTLLLAPATGW 259
Query 247 LYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPT 306
LY A A+ AG WFL +AH+L+A R GEP +PL+LF SN YL +V ALAVDS ++LP
Sbjct 260 LYTAFAIAAGAWFLVLAHRLHAQTRRGEPTKPLKLFHLSNTYLMIVCVALAVDSALSLPV 319
Query 307 L 307
L
Sbjct 320 L 320
>gi|296392902|ref|YP_003657786.1| protoheme IX farnesyltransferase [Segniliparus rotundus DSM 44985]
gi|296180049|gb|ADG96955.1| protoheme IX farnesyltransferase [Segniliparus rotundus DSM 44985]
Length=318
Score = 372 bits (954), Expect = 6e-101, Method: Compositional matrix adjust.
Identities = 188/304 (62%), Positives = 219/304 (73%), Gaps = 0/304 (0%)
Query 4 RGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGG 63
RG AP GR ++ YLALTKPRVIELLLV IP MLLA RG + L+L TL GG
Sbjct 10 RGVSAPSLGAGRVLALARDYLALTKPRVIELLLVATIPVMLLAHRGTVDLRLILETLFGG 69
Query 64 MMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATN 123
+ AA ANTLNCV DADIDKVM RT RPLAR A+ R AL GL L SF WLW + N
Sbjct 70 WLGAASANTLNCVVDADIDKVMDRTKNRPLARGAMSRRAALLFGLGLGSASFLWLWRSAN 129
Query 124 LLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMF 183
LLA L + T+AFYV VY+++LKRRTSQNVVWGGAAGCMP ++GW+A+TG++ WPAL +F
Sbjct 130 LLAASLVVATIAFYVLVYSMFLKRRTSQNVVWGGAAGCMPALVGWAAVTGSLDWPALVVF 189
Query 184 AIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALA 243
+IFFWTPPHTW+LAM+Y+ DY AGVPMLP VA ER V K+++ YTW TV T L
Sbjct 190 MVIFFWTPPHTWSLAMKYRDDYSTAGVPMLPTVADERLVAKRMVWYTWATVLTTFALIPV 249
Query 244 TSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIA 303
LY VA+ AG WFL AH+L AG+ AG PV P RLFLQSNNYLA VF LAVDS +A
Sbjct 250 VGLLYAGVAIAAGSWFLYEAHRLSAGLAAGRPVTPFRLFLQSNNYLAAVFVGLAVDSALA 309
Query 304 LPTL 307
PT+
Sbjct 310 WPTV 313
>gi|317507847|ref|ZP_07965548.1| protoheme IX farnesyltransferase [Segniliparus rugosus ATCC BAA-974]
gi|316253889|gb|EFV13258.1| protoheme IX farnesyltransferase [Segniliparus rugosus ATCC BAA-974]
Length=317
Score = 371 bits (952), Expect = 1e-100, Method: Compositional matrix adjust.
Identities = 187/305 (62%), Positives = 225/305 (74%), Gaps = 1/305 (0%)
Query 4 RGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGG 63
RG P + GR++S + YLALTKPRVIELLLV IP MLLA RG + L+L TL GG
Sbjct 10 RGAPVPS-LAGRSLSLVRDYLALTKPRVIELLLVATIPVMLLAHRGTVDLKLILATLFGG 68
Query 64 MMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATN 123
+ AA ANTLNCV DADIDKVM RT RPLAR A+ R AL GL L + SF WLW N
Sbjct 69 WLGAASANTLNCVVDADIDKVMDRTKNRPLARGAMSVRAALVFGLCLGLASFVWLWRVAN 128
Query 124 LLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMF 183
LL+ L + T+AFYV VY+++LKRRTSQNVVWGGAAGCMP ++GW+A+TG++ WPAL +F
Sbjct 129 LLSAALVVATIAFYVLVYSMYLKRRTSQNVVWGGAAGCMPALVGWAAVTGSLDWPALVVF 188
Query 184 AIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALA 243
+IFFWTPPHTW+LAM+Y++DY AGVPMLP VA ER V ++++ YTW TVA TL+L
Sbjct 189 MVIFFWTPPHTWSLAMKYREDYSAAGVPMLPTVADERLVARRMVWYTWATVATTLLLIPV 248
Query 244 TSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIA 303
LY VA +AG WFL AH+L AG+ +G PV P RLFLQSNNYLA VF LAVDS +A
Sbjct 249 AGPLYAGVATLAGAWFLYEAHRLSAGLASGRPVTPFRLFLQSNNYLAAVFVGLAVDSALA 308
Query 304 LPTLH 308
PT+
Sbjct 309 WPTVS 313
>gi|343924591|ref|ZP_08764139.1| protoheme IX farnesyltransferase [Gordonia alkanivorans NBRC
16433]
gi|343765526|dbj|GAA11065.1| protoheme IX farnesyltransferase [Gordonia alkanivorans NBRC
16433]
Length=330
Score = 370 bits (950), Expect = 1e-100, Method: Compositional matrix adjust.
Identities = 180/295 (62%), Positives = 225/295 (77%), Gaps = 0/295 (0%)
Query 14 GRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTL 73
GR +T+LAY+ALTKPRVIELLLV IP ML ADRG + ++ TL+GG + A ANTL
Sbjct 33 GRVRATVLAYVALTKPRVIELLLVATIPVMLQADRGHVDIAVIAFTLIGGWLGAGSANTL 92
Query 74 NCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVT 133
N V DADIDK MKRT RRPLAR AV TR+AL GL L SF L+ A NLL+ +L T
Sbjct 93 NMVVDADIDKKMKRTERRPLARRAVATRSALIFGLVLWAASFAVLYFAANLLSSLLVSAT 152
Query 134 VAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPH 193
+ FYV VYT+ LKRRT QNVVWGGAAGCMP ++GW+A+TG+I+W + +F +IFFWTPPH
Sbjct 153 IIFYVGVYTMILKRRTWQNVVWGGAAGCMPTLVGWAAVTGSISWQPIVLFLVIFFWTPPH 212
Query 194 TWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVAL 253
TWALAMRYK+DY+ AGVPMLP +ATE +VT+Q+LIYTWLTV ++L L ATSW+Y +AL
Sbjct 213 TWALAMRYKEDYKAAGVPMLPVIATEERVTRQMLIYTWLTVISSLALIPATSWIYTVIAL 272
Query 254 VAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH 308
+AG WFL +LY + G V+PL++FLQSN YLA+VFC LA+D+V+ + T+
Sbjct 273 LAGAWFLERVTKLYRDTKRGAEVKPLKVFLQSNEYLAIVFCGLAIDAVVGMQTIS 327
>gi|256379192|ref|YP_003102852.1| protoheme IX farnesyltransferase [Actinosynnema mirum DSM 43827]
gi|255923495|gb|ACU39006.1| protoheme IX farnesyltransferase [Actinosynnema mirum DSM 43827]
Length=307
Score = 366 bits (940), Expect = 2e-99, Method: Compositional matrix adjust.
Identities = 184/300 (62%), Positives = 226/300 (76%), Gaps = 9/300 (3%)
Query 9 PRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPL-LMLNTLVGGMMAA 67
PR+V G AY+ALTKPRVIELLL+T IPAMLLA+RG + PL L+ TL GG +AA
Sbjct 12 PRQVVG-------AYVALTKPRVIELLLITTIPAMLLAERG-LPPLWLIACTLAGGTLAA 63
Query 68 AGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAG 127
AN LNC DADID VMKRT RPLA+ ++P RNAL G+ L V+SF +LW TNL++
Sbjct 64 GSANALNCYIDADIDSVMKRTGSRPLAKNSIPPRNALIFGVVLGVVSFAFLWITTNLMSA 123
Query 128 VLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIF 187
V A+ T+ FY+FVYTL LKRRTSQN++WGG AGCMPV+IGWSA+TGT+ PALAMF +IF
Sbjct 124 VFAVATILFYIFVYTLVLKRRTSQNIIWGGLAGCMPVVIGWSAVTGTVELPALAMFGVIF 183
Query 188 FWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWL 247
FWTPPHTWALAM++K+DY AGVPMLP VAT +QVT+QI+IY+W TV +L+LA TSW+
Sbjct 184 FWTPPHTWALAMKFKEDYARAGVPMLPVVATAQQVTRQIVIYSWATVLCSLLLAPVTSWI 243
Query 248 YGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
Y VAL +G WF AH+L+ VR G ++ F SN YL +VFC LAVD+V+ LP L
Sbjct 244 YVGVALASGVWFGVFAHRLHGVVRKGGSTNTMKFFHMSNLYLTLVFCGLAVDAVVGLPVL 303
>gi|289574130|ref|ZP_06454357.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
K85]
gi|289538561|gb|EFD43139.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
K85]
Length=191
Score = 360 bits (923), Expect = 2e-97, Method: Compositional matrix adjust.
Identities = 180/182 (99%), Positives = 180/182 (99%), Gaps = 0/182 (0%)
Query 127 GVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAII 186
G ALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAII
Sbjct 10 GCCALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAII 69
Query 187 FFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSW 246
FFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSW
Sbjct 70 FFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSW 129
Query 247 LYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPT 306
LYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPT
Sbjct 130 LYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPT 189
Query 307 LH 308
LH
Sbjct 190 LH 191
>gi|339294427|gb|AEJ46538.1| protoheme IX farnesyltransferase [Mycobacterium tuberculosis
CCDC5079]
Length=292
Score = 357 bits (915), Expect = 2e-96, Method: Compositional matrix adjust.
Identities = 183/195 (94%), Positives = 185/195 (95%), Gaps = 5/195 (2%)
Query 17 MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV 76
MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV
Sbjct 1 MSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCV 60
Query 77 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 136
ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF
Sbjct 61 ADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAF 120
Query 137 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWA 196
YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTW
Sbjct 121 YVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWC 180
Query 197 LAMRYKQDYQVAGVP 211
+ D AG+P
Sbjct 181 IG-----DALQAGLP 190
>gi|326382197|ref|ZP_08203889.1| protoheme IX farnesyltransferase [Gordonia neofelifaecis NRRL
B-59395]
gi|326198927|gb|EGD56109.1| protoheme IX farnesyltransferase [Gordonia neofelifaecis NRRL
B-59395]
Length=318
Score = 353 bits (907), Expect = 1e-95, Method: Compositional matrix adjust.
Identities = 171/300 (57%), Positives = 223/300 (75%), Gaps = 7/300 (2%)
Query 15 RAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLN 74
R +T+LAY+ALTKPRVIELLLV+ IP ML A+RG++ L+L T+VGG + AA AN+LN
Sbjct 15 RVWNTVLAYIALTKPRVIELLLVSTIPVMLQAERGSVDIALILITVVGGWLGAASANSLN 74
Query 75 CVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCAT-------NLLAG 127
VADADID+ MKRT RRPLAR AVP RNAL G+ L +SF L+ T + L
Sbjct 75 MVADADIDQKMKRTERRPLARHAVPVRNALVFGIVLAALSFAVLYFGTANSAGERSFLPS 134
Query 128 VLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIF 187
+L ++T+ FYV VYTL LKRRT QNV+WGGAAGCMP ++GW+A+T +++W MF ++F
Sbjct 135 ILVMITIGFYVGVYTLILKRRTWQNVIWGGAAGCMPALVGWAAVTHSLSWQPFVMFLVVF 194
Query 188 FWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWL 247
FWTPPHTWALAMRY++DY+ AGVPM P +A++ +VT +L+YTWLTV + L ATSW+
Sbjct 195 FWTPPHTWALAMRYREDYRAAGVPMFPVIASDERVTTHMLVYTWLTVLTSFFLIPATSWI 254
Query 248 YGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTL 307
Y VA+ +G WF+ M +LY R G V+PL++FL SN YLA++FC LAVD+VI LPT+
Sbjct 255 YLVVAVGSGAWFIYMVTKLYVETRRGVEVKPLKIFLTSNEYLALLFCGLAVDAVINLPTI 314
Lambda K H
0.328 0.137 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 524399257434
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40