BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1475c

Length=943
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608613|ref|NP_215991.1|  aconitate hydratase [Mycobacterium ...  1939    0.0  
gi|289574156|ref|ZP_06454383.1|  iron-regulated aconitate hydrata...  1938    0.0  
gi|289750036|ref|ZP_06509414.1|  iron-regulated aconitate hydrata...  1937    0.0  
gi|340626490|ref|YP_004744942.1|  putative iron-regulated aconita...  1933    0.0  
gi|254550492|ref|ZP_05140939.1|  aconitate hydratase [Mycobacteri...  1930    0.0  
gi|162138271|ref|YP_905477.2|  aconitate hydratase [Mycobacterium...  1715    0.0  
gi|118569255|gb|ABL04006.1|  aconitate hydratase Acn [Mycobacteri...  1714    0.0  
gi|336458028|gb|EGO37015.1|  aconitase A [Mycobacterium avium sub...  1711    0.0  
gi|183982295|ref|YP_001850586.1|  aconitate hydratase Acn [Mycoba...  1708    0.0  
gi|240172219|ref|ZP_04750878.1|  aconitate hydratase [Mycobacteri...  1687    0.0  
gi|289757587|ref|ZP_06516965.1|  iron-regulated aconitate hydrata...  1687    0.0  
gi|41395651|gb|AAS03518.1|  Acn [Mycobacterium avium subsp. parat...  1684    0.0  
gi|161579546|ref|YP_882485.2|  aconitate hydratase [Mycobacterium...  1684    0.0  
gi|161611206|ref|NP_960135.2|  aconitate hydratase [Mycobacterium...  1683    0.0  
gi|296170664|ref|ZP_06852239.1|  aconitate hydratase [Mycobacteri...  1681    0.0  
gi|254775748|ref|ZP_05217264.1|  aconitate hydratase [Mycobacteri...  1680    0.0  
gi|118167565|gb|ABK68462.1|  aconitate hydratase 1 [Mycobacterium...  1680    0.0  
gi|342858766|ref|ZP_08715421.1|  aconitate hydratase [Mycobacteri...  1673    0.0  
gi|254819545|ref|ZP_05224546.1|  aconitate hydratase [Mycobacteri...  1672    0.0  
gi|15827972|ref|NP_302235.1|  aconitate hydratase [Mycobacterium ...  1667    0.0  
gi|315444585|ref|YP_004077464.1|  aconitase [Mycobacterium sp. Sp...  1599    0.0  
gi|126435070|ref|YP_001070761.1|  aconitate hydratase [Mycobacter...  1599    0.0  
gi|145224249|ref|YP_001134927.1|  aconitate hydratase [Mycobacter...  1596    0.0  
gi|108799416|ref|YP_639613.1|  aconitate hydratase [Mycobacterium...  1585    0.0  
gi|118471676|ref|YP_887458.1|  aconitate hydratase 1 [Mycobacteri...  1568    0.0  
gi|333990879|ref|YP_004523493.1|  aconitate hydratase Acn [Mycoba...  1568    0.0  
gi|120403729|ref|YP_953558.1|  aconitate hydratase 1 [Mycobacteri...  1540    0.0  
gi|296393883|ref|YP_003658767.1|  aconitate hydratase 1 [Segnilip...  1532    0.0  
gi|333919582|ref|YP_004493163.1|  Aconitate hydratase 1 [Amycolic...  1530    0.0  
gi|317508709|ref|ZP_07966364.1|  aconitate hydratase 1 [Segnilipa...  1529    0.0  
gi|312139641|ref|YP_004006977.1|  aconitate hydratase [Rhodococcu...  1527    0.0  
gi|3121732|sp|O08451.1|ACON_MYCAV  RecName: Full=Aconitate hydrat...  1526    0.0  
gi|169629814|ref|YP_001703463.1|  aconitate hydratase ACN [Mycoba...  1526    0.0  
gi|111024157|ref|YP_707129.1|  aconitate hydratase [Rhodococcus j...  1524    0.0  
gi|54025453|ref|YP_119695.1|  aconitate hydratase [Nocardia farci...  1519    0.0  
gi|302527156|ref|ZP_07279498.1|  aconitate hydratase 1 [Streptomy...  1517    0.0  
gi|326382232|ref|ZP_08203924.1|  aconitate hydratase [Gordonia ne...  1513    0.0  
gi|324998571|ref|ZP_08119683.1|  aconitate hydratase 1 [Pseudonoc...  1511    0.0  
gi|258652503|ref|YP_003201659.1|  aconitate hydratase 1 [Nakamure...  1511    0.0  
gi|257056245|ref|YP_003134077.1|  aconitase [Saccharomonospora vi...  1509    0.0  
gi|296139783|ref|YP_003647026.1|  aconitate hydratase 1 [Tsukamur...  1506    0.0  
gi|343927993|ref|ZP_08767459.1|  aconitase [Gordonia alkanivorans...  1504    0.0  
gi|229493658|ref|ZP_04387443.1|  aconitate hydratase 1 [Rhodococc...  1503    0.0  
gi|226306555|ref|YP_002766515.1|  aconitase [Rhodococcus erythrop...  1503    0.0  
gi|226366404|ref|YP_002784187.1|  aconitate hydratase [Rhodococcu...  1502    0.0  
gi|300786832|ref|YP_003767123.1|  aconitate hydratase 1 [Amycolat...  1489    0.0  
gi|262202328|ref|YP_003273536.1|  aconitate hydratase 1 [Gordonia...  1477    0.0  
gi|134100346|ref|YP_001106007.1|  aconitate hydratase [Saccharopo...  1476    0.0  
gi|291007683|ref|ZP_06565656.1|  aconitate hydratase [Saccharopol...  1476    0.0  
gi|331697181|ref|YP_004333420.1|  aconitate hydratase 1 [Pseudono...  1451    0.0  


>gi|15608613|ref|NP_215991.1| aconitate hydratase [Mycobacterium tuberculosis H37Rv]
 gi|15840936|ref|NP_335973.1| aconitate hydratase [Mycobacterium tuberculosis CDC1551]
 gi|31792670|ref|NP_855163.1| aconitate hydratase [Mycobacterium bovis AF2122/97]
 64 more sequence titles
 Length=943

 Score = 1939 bits (5023),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 942/943 (99%), Positives = 943/943 (100%), Gaps = 0/943 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            +TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
Sbjct  1    MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
Sbjct  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
Sbjct  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
Sbjct  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
Sbjct  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
Sbjct  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
Sbjct  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD
Sbjct  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
Sbjct  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV
Sbjct  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ
Sbjct  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
Sbjct  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943


>gi|289574156|ref|ZP_06454383.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
K85]
 gi|289538587|gb|EFD43165.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
K85]
Length=943

 Score = 1938 bits (5021),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 941/943 (99%), Positives = 943/943 (100%), Gaps = 0/943 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            +TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
Sbjct  1    MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
Sbjct  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
Sbjct  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFP+DEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
Sbjct  301  SPEFGSTAAIFPVDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
Sbjct  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
Sbjct  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
Sbjct  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD
Sbjct  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
Sbjct  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV
Sbjct  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ
Sbjct  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
Sbjct  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943


>gi|289750036|ref|ZP_06509414.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
T92]
 gi|289690623|gb|EFD58052.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
T92]
Length=943

 Score = 1937 bits (5019),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 941/943 (99%), Positives = 942/943 (99%), Gaps = 0/943 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            +TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
Sbjct  1    MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
Sbjct  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
Sbjct  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
Sbjct  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQLTFANDDVATDETVHSAA HADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
Sbjct  421  SDPGQLTFANDDVATDETVHSAATHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
Sbjct  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
Sbjct  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD
Sbjct  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
Sbjct  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV
Sbjct  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ
Sbjct  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
Sbjct  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943


>gi|340626490|ref|YP_004744942.1| putative iron-regulated aconitate hydratase [Mycobacterium canettii 
CIPT 140010059]
 gi|340004680|emb|CCC43824.1| putative iron-regulated aconitate hydratase ACN (citrate hydro-lyase) 
(aconitase) [Mycobacterium canettii CIPT 140010059]
Length=943

 Score = 1933 bits (5007),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 938/943 (99%), Positives = 941/943 (99%), Gaps = 0/943 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            +TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
Sbjct  1    MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
Sbjct  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
Sbjct  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
Sbjct  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
Sbjct  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGL +KPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
Sbjct  481  NTSNPEVMLGAALLARNAVEKGLAAKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
Sbjct  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GDDRWRNLPTPSGNTF+WDPNSTYVRKPPYFEGMTAKPEPVGNI GARVLALLGDSVTTD
Sbjct  661  GDDRWRNLPTPSGNTFDWDPNSTYVRKPPYFEGMTAKPEPVGNIRGARVLALLGDSVTTD  720

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
Sbjct  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV
Sbjct  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ
Sbjct  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
Sbjct  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943


>gi|254550492|ref|ZP_05140939.1| aconitate hydratase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297634041|ref|ZP_06951821.1| aconitate hydratase [Mycobacterium tuberculosis KZN 4207]
 gi|297731027|ref|ZP_06960145.1| aconitate hydratase [Mycobacterium tuberculosis KZN R506]
 gi|313658360|ref|ZP_07815240.1| aconitate hydratase [Mycobacterium tuberculosis KZN V2475]
 gi|339294450|gb|AEJ46561.1| aconitate hydratase [Mycobacterium tuberculosis CCDC5079]
 gi|339298090|gb|AEJ50200.1| aconitate hydratase [Mycobacterium tuberculosis CCDC5180]
Length=938

 Score = 1930 bits (4999),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 937/938 (99%), Positives = 938/938 (100%), Gaps = 0/938 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI
Sbjct  61   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG
Sbjct  241  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV
Sbjct  301  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ
Sbjct  361  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  420

Query  426  LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP  485
            LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP
Sbjct  421  LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP  480

Query  486  EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC  545
            EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC
Sbjct  481  EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC  540

Query  546  TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA  605
            TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA
Sbjct  541  TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA  600

Query  606  GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW  665
            GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW
Sbjct  601  GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW  660

Query  666  RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA  725
            RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA
Sbjct  661  RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA  720

Query  726  GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  785
            GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR
Sbjct  721  GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  780

Query  786  DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  845
            DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF
Sbjct  781  DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  840

Query  846  ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD  905
            ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD
Sbjct  841  ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD  900

Query  906  GATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            GATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
Sbjct  901  GATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  938


>gi|162138271|ref|YP_905477.2| aconitate hydratase [Mycobacterium ulcerans Agy99]
Length=939

 Score = 1715 bits (4442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 858/942 (92%), Positives = 892/942 (95%), Gaps = 5/942 (0%)

Query  2    TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHI  61
            T  SVNSFGA +TL+VG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHI
Sbjct  3    TKDSVNSFGARNTLEVGDKSYQIYRLDAVPNTKKLPYSLKVLAENLLRNEDGSNITKDHI  62

Query  62   EAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPA  121
            EAIANWDP+AEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI DLGG PDKVNPLAPA
Sbjct  63   EAIANWDPQAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGQPDKVNPLAPA  122

Query  122  DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV  181
            DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV
Sbjct  123  DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV  182

Query  182  NIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP  241
            NIEYLASVVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP
Sbjct  183  NIEYLASVVMDRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP  242

Query  242  RVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMS  301
            RVVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMS
Sbjct  243  RVVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMS  302

Query  302  PEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNL  361
            PEFGSTAAIFPIDEETIKYL  TGR+ EQVALV AYAK QGMWHDPKHEP FSEYLELNL
Sbjct  303  PEFGSTAAIFPIDEETIKYLELTGRSAEQVALVAAYAKEQGMWHDPKHEPVFSEYLELNL  362

Query  362  SDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPAS  421
            SDVVPSIAGPKRPQDRI LA+AK TFREQI HYV + S  S HD HSKLDEVVEETFPAS
Sbjct  363  SDVVPSIAGPKRPQDRIVLAEAKGTFREQITHYVSDDS--SAHDQHSKLDEVVEETFPAS  420

Query  422  DPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            DPGQLTFANDDVA    VHSAAAHADGRVS PVRV+SDELGEFVLDHGAVVIAAITSCTN
Sbjct  421  DPGQLTFANDDVAA---VHSAAAHADGRVSKPVRVRSDELGEFVLDHGAVVIAAITSCTN  477

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAV+KGLTSKPWVKTT+APGSQVVNDYYD++GLWPYLEKLGF+LV
Sbjct  478  TSNPEVMLGAALLARNAVDKGLTSKPWVKTTMAPGSQVVNDYYDKAGLWPYLEKLGFFLV  537

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKAVNDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  538  GYGCTTCIGNSGPLPEEISKAVNDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVA  597

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG DK+GK+VFLRDIWPSQQDV+DTIA+AINQEMFT+NYADVFKG
Sbjct  598  YALAGTMDFDFENQPLGTDKEGKDVFLRDIWPSQQDVADTIASAINQEMFTKNYADVFKG  657

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTF+WD +STYVRKPPYFEGM A P PV +I+GARVLALLGDSVTTDH
Sbjct  658  DERWRNLPTPSGNTFDWDQSSTYVRKPPYFEGMAAAPAPVSDITGARVLALLGDSVTTDH  717

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAGAIKPGTPAA+YLDEHGV RKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG
Sbjct  718  ISPAGAIKPGTPAAQYLDEHGVARKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  777

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ G PQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGTLLLGVR VI
Sbjct  778  GYTRDFTQDGAPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRVVI  837

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP G+SASSLGLDGTE FD+TGI+ LN GKTPKTV V+A
Sbjct  838  AESFERIHRSNLIGMGVIPLQFPTGQSASSLGLDGTETFDVTGIEELNSGKTPKTVHVKA  897

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            TK     IEFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  898  TKDGADPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  939


>gi|118569255|gb|ABL04006.1| aconitate hydratase Acn [Mycobacterium ulcerans Agy99]
Length=943

 Score = 1714 bits (4440),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 858/942 (92%), Positives = 892/942 (95%), Gaps = 5/942 (0%)

Query  2    TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHI  61
            T  SVNSFGA +TL+VG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHI
Sbjct  7    TKDSVNSFGARNTLEVGDKSYQIYRLDAVPNTKKLPYSLKVLAENLLRNEDGSNITKDHI  66

Query  62   EAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPA  121
            EAIANWDP+AEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI DLGG PDKVNPLAPA
Sbjct  67   EAIANWDPQAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGQPDKVNPLAPA  126

Query  122  DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV  181
            DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV
Sbjct  127  DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV  186

Query  182  NIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP  241
            NIEYLASVVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP
Sbjct  187  NIEYLASVVMDRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP  246

Query  242  RVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMS  301
            RVVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMS
Sbjct  247  RVVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMS  306

Query  302  PEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNL  361
            PEFGSTAAIFPIDEETIKYL  TGR+ EQVALV AYAK QGMWHDPKHEP FSEYLELNL
Sbjct  307  PEFGSTAAIFPIDEETIKYLELTGRSAEQVALVAAYAKEQGMWHDPKHEPVFSEYLELNL  366

Query  362  SDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPAS  421
            SDVVPSIAGPKRPQDRI LA+AK TFREQI HYV + S  S HD HSKLDEVVEETFPAS
Sbjct  367  SDVVPSIAGPKRPQDRIVLAEAKGTFREQITHYVSDDS--SAHDQHSKLDEVVEETFPAS  424

Query  422  DPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            DPGQLTFANDDVA    VHSAAAHADGRVS PVRV+SDELGEFVLDHGAVVIAAITSCTN
Sbjct  425  DPGQLTFANDDVAA---VHSAAAHADGRVSKPVRVRSDELGEFVLDHGAVVIAAITSCTN  481

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAV+KGLTSKPWVKTT+APGSQVVNDYYD++GLWPYLEKLGF+LV
Sbjct  482  TSNPEVMLGAALLARNAVDKGLTSKPWVKTTMAPGSQVVNDYYDKAGLWPYLEKLGFFLV  541

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKAVNDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVA  601

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG DK+GK+VFLRDIWPSQQDV+DTIA+AINQEMFT+NYADVFKG
Sbjct  602  YALAGTMDFDFENQPLGTDKEGKDVFLRDIWPSQQDVADTIASAINQEMFTKNYADVFKG  661

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTF+WD +STYVRKPPYFEGM A P PV +I+GARVLALLGDSVTTDH
Sbjct  662  DERWRNLPTPSGNTFDWDQSSTYVRKPPYFEGMAAAPAPVSDITGARVLALLGDSVTTDH  721

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAGAIKPGTPAA+YLDEHGV RKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG
Sbjct  722  ISPAGAIKPGTPAAQYLDEHGVARKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ G PQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGTLLLGVR VI
Sbjct  782  GYTRDFTQDGAPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRVVI  841

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP G+SASSLGLDGTE FD+TGI+ LN GKTPKTV V+A
Sbjct  842  AESFERIHRSNLIGMGVIPLQFPTGQSASSLGLDGTETFDVTGIEELNSGKTPKTVHVKA  901

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            TK     IEFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  902  TKDGADPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  943


>gi|336458028|gb|EGO37015.1| aconitase A [Mycobacterium avium subsp. paratuberculosis S397]
Length=937

 Score = 1711 bits (4430),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 834/942 (89%), Positives = 882/942 (94%), Gaps = 7/942 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIE
Sbjct  2    TDSVNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIE  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPAD
Sbjct  62   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVN
Sbjct  122  LVIDHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVM RDGVAYPDTCVGTDSHTTMVNGLG+LGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLARVVMERDGVAYPDTCVGTDSHTTMVNGLGMLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPIDEETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  302  EFGSTAAIFPIDEETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASD
Sbjct  362  QVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASD  418

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG  +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTN
Sbjct  419  PGAPSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTN  475

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLV
Sbjct  476  TSNPEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLV  535

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  536  GYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVA  595

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKG
Sbjct  596  YALAGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKG  655

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDH
Sbjct  656  DERWRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDH  715

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+G
Sbjct  716  ISPAGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAG  775

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  776  GYTRDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  835

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  836  AESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKA  895

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K     +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  896  SKNGSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  937


>gi|183982295|ref|YP_001850586.1| aconitate hydratase Acn [Mycobacterium marinum M]
 gi|183175621|gb|ACC40731.1| aconitate hydratase Acn [Mycobacterium marinum M]
Length=933

 Score = 1708 bits (4423),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 853/938 (91%), Positives = 890/938 (95%), Gaps = 5/938 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA +TL+VG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGARNTLEVGDKSYQIYRLDAVPNTKKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDP+AEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI DLGG PDKVNPLAPADLVI
Sbjct  61   NWDPQAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGQPDKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LASVVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LASVVMDRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            F+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG
Sbjct  241  FKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFPIDEETIKYL  TGR+ EQVALV AYAK QGMWHDPKHEP  SEYLELNLSDVV
Sbjct  301  STAAIFPIDEETIKYLELTGRSAEQVALVAAYAKEQGMWHDPKHEPVLSEYLELNLSDVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRI L++AK TFREQI HYV + S  S HD HSKLDEVVEETFPASDPGQ
Sbjct  361  PSIAGPKRPQDRIVLSEAKGTFREQITHYVSDDS--SAHDQHSKLDEVVEETFPASDPGQ  418

Query  426  LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP  485
            LTFANDDVA    VHSAAAHADGRVS PVRV+SDELGEFVLDHGAVVIAAITSCTNTSNP
Sbjct  419  LTFANDDVAA---VHSAAAHADGRVSKPVRVRSDELGEFVLDHGAVVIAAITSCTNTSNP  475

Query  486  EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC  545
            EVMLGAALLARNAV+KGLTSKPWVKTT+APGSQVVNDYYD++GLWPYLEKLGFYLVGYGC
Sbjct  476  EVMLGAALLARNAVDKGLTSKPWVKTTMAPGSQVVNDYYDKAGLWPYLEKLGFYLVGYGC  535

Query  546  TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA  605
            TTCIGNSGPLPE+ISKAVNDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLV+AYALA
Sbjct  536  TTCIGNSGPLPEDISKAVNDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALA  595

Query  606  GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW  665
            GTMDFDF+ QPLG DK+GK+VFLRDIWPSQQDV+DTIA+AINQEMFT+NYADVFKGD+RW
Sbjct  596  GTMDFDFENQPLGTDKEGKDVFLRDIWPSQQDVADTIASAINQEMFTKNYADVFKGDERW  655

Query  666  RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA  725
            RNLPTPSGNTF+WD +STYVRKPPYFEGM A P PV +I+GARVLALLGDSVTTDHISPA
Sbjct  656  RNLPTPSGNTFDWDQSSTYVRKPPYFEGMAAAPTPVSDITGARVLALLGDSVTTDHISPA  715

Query  726  GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  785
            GAIKPGTPAA+YLDEHGV RKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR
Sbjct  716  GAIKPGTPAAQYLDEHGVARKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  775

Query  786  DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  845
            DFTQ G PQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGTLLLGVR VIAESF
Sbjct  776  DFTQDGAPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRVVIAESF  835

Query  846  ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD  905
            ERIHRSNLIGMGVIPLQFP+G+SASSLGLDGTE FD+TGI+ LN GKTPKTV V+ATK  
Sbjct  836  ERIHRSNLIGMGVIPLQFPKGQSASSLGLDGTETFDVTGIEELNSGKTPKTVHVKATKDG  895

Query  906  GATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
               IEFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  896  ADPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  933


>gi|240172219|ref|ZP_04750878.1| aconitate hydratase [Mycobacterium kansasii ATCC 12478]
Length=935

 Score = 1687 bits (4369),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/940 (89%), Positives = 887/940 (95%), Gaps = 7/940 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA +TLKVG++SYQIYRLDAVPNT +LPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGARNTLKVGDRSYQIYRLDAVPNTKRLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDP+AEPS+EIQYTPARVVMQDFTGVPCIVDLATMREAIADLGG PDKVNPLAPADLVI
Sbjct  61   NWDPEAEPSVEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGKPDKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFRDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LASVVM RDGVAYPDT VGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LASVVMDRDGVAYPDTVVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            F+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYG GVAEVPLANRATLGNMSPEFG
Sbjct  241  FKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGAGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFPIDEETI YLRFTGR PEQ+ALVEAYAK QGMWHDPKHEP +SEY+EL+LSDVV
Sbjct  301  STAAIFPIDEETISYLRFTGRDPEQLALVEAYAKEQGMWHDPKHEPAYSEYIELDLSDVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRIAL+ AKSTFREQI +YVG+   D     +SKLDE+V+ETFPASDPG 
Sbjct  361  PSIAGPKRPQDRIALSDAKSTFREQIPNYVGD---DPDKKDYSKLDEMVDETFPASDPGA  417

Query  426  LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP  485
            L+  + D      V SAA HA GRVSNPV VKSDELGEFVLDHGAVVIAA+TSCTNTSNP
Sbjct  418  LSNGHAD--DHAPVESAAKHAKGRVSNPVTVKSDELGEFVLDHGAVVIAAVTSCTNTSNP  475

Query  486  EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC  545
            EVMLGAALLA+NAVEKGL +KPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLVGYGC
Sbjct  476  EVMLGAALLAKNAVEKGLAAKPWVKTTMAPGSQVVSDYYDKAGLWPYLEKLGFYLVGYGC  535

Query  546  TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA  605
            TTCIGNSGPLPEEISKA+NDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLV+AYALA
Sbjct  536  TTCIGNSGPLPEEISKAINDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALA  595

Query  606  GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW  665
            GTMDFDF++Q LG DKDG +V+L+DIWPSQ+DVSDTIA+AINQEMFT+NYADVFKGD+RW
Sbjct  596  GTMDFDFESQKLGTDKDGNDVYLKDIWPSQKDVSDTIASAINQEMFTKNYADVFKGDERW  655

Query  666  RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA  725
            RNLPTP GNTFEWD +STYVRKPPYFEGM+A+PEPV NI+GARVLALLGDSVTTDHISPA
Sbjct  656  RNLPTPGGNTFEWDQDSTYVRKPPYFEGMSAEPEPVRNITGARVLALLGDSVTTDHISPA  715

Query  726  GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  785
            G+IKPGTPAA+YLDEHGV+RKDYNSFGSRRGNHEVMIRGTFANIRLRNQLL+DVSGGYTR
Sbjct  716  GSIKPGTPAAQYLDEHGVERKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLEDVSGGYTR  775

Query  786  DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  845
            DFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGTLLLGVRAVIAESF
Sbjct  776  DFTQEGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  835

Query  846  ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD  905
            ERIHRSNLIGMGVIPLQFPEG+SASSLGLDGTEVFDITGI  LNDGKTPKTV V+A+K  
Sbjct  836  ERIHRSNLIGMGVIPLQFPEGESASSLGLDGTEVFDITGIAALNDGKTPKTVHVKASKNA  895

Query  906  G--ATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            G  A +EFDAVVRIDTPGEADYYRNGGILQ+VLRN+LKSG
Sbjct  896  GGDAAVEFDAVVRIDTPGEADYYRNGGILQFVLRNMLKSG  935


>gi|289757587|ref|ZP_06516965.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
T85]
 gi|289713151|gb|EFD77163.1| iron-regulated aconitate hydratase acn [Mycobacterium tuberculosis 
T85]
Length=839

 Score = 1687 bits (4368),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 817/820 (99%), Positives = 818/820 (99%), Gaps = 0/820 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            +TSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
Sbjct  1    MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
Sbjct  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
Sbjct  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
Sbjct  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
Sbjct  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
Sbjct  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
Sbjct  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD
Sbjct  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
Sbjct  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYG  820
            GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGK  G
Sbjct  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKSTG  820


>gi|41395651|gb|AAS03518.1| Acn [Mycobacterium avium subsp. paratuberculosis K-10]
Length=959

 Score = 1684 bits (4362),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 834/942 (89%), Positives = 881/942 (94%), Gaps = 7/942 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIE
Sbjct  24   TDSVNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIE  83

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPAD
Sbjct  84   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD  143

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG AD FERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVN
Sbjct  144  LVIDHSVIADLFGTADTFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVN  203

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  204  IEYLARVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  263

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSP
Sbjct  264  VVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  323

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPIDEETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  324  EFGSTAAIFPIDEETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLS  383

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASD
Sbjct  384  QVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASD  440

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG  +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTN
Sbjct  441  PGAPSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTN  497

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLV
Sbjct  498  TSNPEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLV  557

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  558  GYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVA  617

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKG
Sbjct  618  YALAGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKG  677

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDH
Sbjct  678  DERWRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDH  737

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+G
Sbjct  738  ISPAGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAG  797

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  798  GYTRDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  857

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  858  AESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKA  917

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K     +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  918  SKNGSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  959


>gi|161579546|ref|YP_882485.2| aconitate hydratase [Mycobacterium avium 104]
Length=937

 Score = 1684 bits (4360),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 834/942 (89%), Positives = 882/942 (94%), Gaps = 7/942 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIE
Sbjct  2    TDSVNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIE  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPAD
Sbjct  62   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVN
Sbjct  122  LVIDHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLARVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID+ETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  302  EFGSTAAIFPIDQETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASD
Sbjct  362  QVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASD  418

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG  +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTN
Sbjct  419  PGAPSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTN  475

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLV
Sbjct  476  TSNPEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLV  535

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  536  GYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVA  595

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKG
Sbjct  596  YALAGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKG  655

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDH
Sbjct  656  DERWRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDH  715

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+G
Sbjct  716  ISPAGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAG  775

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  776  GYTRDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  835

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  836  AESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKA  895

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K     +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  896  SKNGSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  937


>gi|161611206|ref|NP_960135.2| aconitate hydratase [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=937

 Score = 1683 bits (4359),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 834/942 (89%), Positives = 881/942 (94%), Gaps = 7/942 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIE
Sbjct  2    TDSVNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIE  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPAD
Sbjct  62   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG AD FERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVN
Sbjct  122  LVIDHSVIADLFGTADTFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLARVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPIDEETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  302  EFGSTAAIFPIDEETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASD
Sbjct  362  QVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASD  418

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG  +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTN
Sbjct  419  PGAPSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTN  475

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLV
Sbjct  476  TSNPEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLV  535

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  536  GYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVA  595

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKG
Sbjct  596  YALAGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKG  655

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDH
Sbjct  656  DERWRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDH  715

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+G
Sbjct  716  ISPAGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAG  775

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  776  GYTRDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  835

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  836  AESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKA  895

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K     +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  896  SKNGSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  937


>gi|296170664|ref|ZP_06852239.1| aconitate hydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295894653|gb|EFG74387.1| aconitate hydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=932

 Score = 1681 bits (4354),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 831/937 (89%), Positives = 878/937 (94%), Gaps = 5/937 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA DTL+VG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSN+TKDHIEAIA
Sbjct  1    MNSFGARDTLEVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNVTKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI DLGG  +KVNPLAPADLVI
Sbjct  61   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGKAEKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFRDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LASVVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LASVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            F+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG
Sbjct  241  FKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFP+DEETI YLRFTGR+ EQ+ALVEAYAK QGMWHDPKHEP FSEYLEL+LSDVV
Sbjct  301  STAAIFPVDEETISYLRFTGRSDEQLALVEAYAKEQGMWHDPKHEPAFSEYLELDLSDVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRI L+ AKSTFR QI  YVG+  PD     +SKLDE V+E+FPASDPG 
Sbjct  361  PSIAGPKRPQDRIPLSDAKSTFRGQIGDYVGD-DPDKKE--YSKLDEAVDESFPASDPGA  417

Query  426  LTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNP  485
            L   + D A      SAAAHA GRVS+PVRVKSDE GEF LDHGAVVIAA+TSCTNTSNP
Sbjct  418  LENGHADDAP--KFESAAAHAKGRVSSPVRVKSDERGEFELDHGAVVIAAVTSCTNTSNP  475

Query  486  EVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGC  545
            EVMLGAALLARNAVEKGL SKPWVKT++APGSQVV+DYYD++GLWPYLEKLGFYLVGYGC
Sbjct  476  EVMLGAALLARNAVEKGLASKPWVKTSMAPGSQVVSDYYDKAGLWPYLEKLGFYLVGYGC  535

Query  546  TTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALA  605
            TTCIGNSGPLP+EISKA+NDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLV+AYALA
Sbjct  536  TTCIGNSGPLPDEISKAINDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALA  595

Query  606  GTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRW  665
            GTMDFDF  QPLG DK+GK+VFL+DIWPSQ+DVSDTIA+AINQEMFT+NY+DVFKGD+RW
Sbjct  596  GTMDFDFDQQPLGTDKEGKDVFLKDIWPSQKDVSDTIASAINQEMFTKNYSDVFKGDERW  655

Query  666  RNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPA  725
            RNLPTPSGNTFEW+P+STYVRKPPYFEGM+A PEPV +I GARVLALLGDSVTTDHISPA
Sbjct  656  RNLPTPSGNTFEWNPDSTYVRKPPYFEGMSADPEPVRDIEGARVLALLGDSVTTDHISPA  715

Query  726  GAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  785
            GAIKPGTPAA+YLDEHGV+RKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR
Sbjct  716  GAIKPGTPAAQYLDEHGVERKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTR  775

Query  786  DFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  845
            DFTQ G PQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGTLLLGVRAVIAESF
Sbjct  776  DFTQDGAPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRAVIAESF  835

Query  846  ERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGD  905
            ERIHRSNLIGMGVIPLQFPEGKSA  LGLDGTEVFDITGI+ +NDGKTPKTV V+ATK  
Sbjct  836  ERIHRSNLIGMGVIPLQFPEGKSAKELGLDGTEVFDITGIEAINDGKTPKTVHVKATKES  895

Query  906  GATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            G  +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  896  GDPVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  932


>gi|254775748|ref|ZP_05217264.1| aconitate hydratase [Mycobacterium avium subsp. avium ATCC 25291]
Length=933

 Score = 1680 bits (4351),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 832/939 (89%), Positives = 880/939 (94%), Gaps = 7/939 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPADLVI
Sbjct  61   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LA VVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LARVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            F+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG
Sbjct  241  FKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFPID+ETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS VV
Sbjct  301  STAAIFPIDQETIDYLKFTGRKAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLSQVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASDPG 
Sbjct  361  PSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASDPGA  417

Query  426  LTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTNTSN
Sbjct  418  PSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTNTSN  474

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            PEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLVGYG
Sbjct  475  PEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLVGYG  534

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+AYAL
Sbjct  535  CTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVAYAL  594

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKGD+R
Sbjct  595  AGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKGDER  654

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDHISP
Sbjct  655  WRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDHISP  714

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+GGYT
Sbjct  715  AGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAGGYT  774

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVIAES
Sbjct  775  RDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAES  834

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A+K 
Sbjct  835  FERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKASKN  894

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
                +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  895  GSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  933


>gi|118167565|gb|ABK68462.1| aconitate hydratase 1 [Mycobacterium avium 104]
Length=933

 Score = 1680 bits (4350),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 832/939 (89%), Positives = 880/939 (94%), Gaps = 7/939 (0%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA +TLKVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGARNTLKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPADLVI
Sbjct  61   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  245
            LA VVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG
Sbjct  181  LARVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVG  240

Query  246  FRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  305
            F+LTGEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG
Sbjct  241  FKLTGEIQPGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFG  300

Query  306  STAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVV  365
            STAAIFPID+ETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS VV
Sbjct  301  STAAIFPIDQETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLSQVV  360

Query  366  PSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQ  425
            PSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASDPG 
Sbjct  361  PSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASDPGA  417

Query  426  LTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTNTSN
Sbjct  418  PSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTNTSN  474

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            PEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLVGYG
Sbjct  475  PEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLVGYG  534

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+AYAL
Sbjct  535  CTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVAYAL  594

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+ QPLG+DKDG +V+L+DIWPSQ+DVSDTIA+AIN EMFT+NYADVFKGD+R
Sbjct  595  AGTMDFDFEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKGDER  654

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WRNLPTPSGNTFEW P+STYVRKPPYFEGM A+PEPV +ISGARVLALLGDSVTTDHISP
Sbjct  655  WRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLALLGDSVTTDHISP  714

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG+IKPGTPAA+YLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDV+GGYT
Sbjct  715  AGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVAGGYT  774

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVIAES
Sbjct  775  RDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAES  834

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A+K 
Sbjct  835  FERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKASKN  894

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
                +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  895  GSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  933


>gi|342858766|ref|ZP_08715421.1| aconitate hydratase [Mycobacterium colombiense CECT 3035]
 gi|342134470|gb|EGT87650.1| aconitate hydratase [Mycobacterium colombiense CECT 3035]
Length=938

 Score = 1673 bits (4333),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 829/942 (89%), Positives = 881/942 (94%), Gaps = 6/942 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSF A DTLKVG++SYQIYRLDAVPNT KLPYSLKVLAENLLRNEDG+NITKDHIE
Sbjct  2    TDSVNSFEARDTLKVGDQSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGANITKDHIE  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI DLGG  +KVNPLAPAD
Sbjct  62   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGKAEKVNPLAPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG ADAFERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVN
Sbjct  122  LVIDHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFQDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLASVVM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLASVVMERDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQ GVTATDVVLTVTEMLR+HGVVGKFVEFYG+GV+EVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQAGVTATDVVLTVTEMLRKHGVVGKFVEFYGKGVSEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPIDEETI YL+FTGRT +Q+ALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  302  EFGSTAAIFPIDEETISYLKFTGRTDQQLALVETYAKEQGLWHDPDHEPAFSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+ AKSTFR+QI  YV +G  DS    +SKLDE VEETFPASD
Sbjct  362  TVVPSIAGPKRPQDRIALSAAKSTFRDQILSYV-DGDTDS-QQGYSKLDESVEETFPASD  419

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG ++  + DDV     VHSAAAHA GR SNPV VKSDE GEFVLDHGAVVIAA+TSCTN
Sbjct  420  PGAVSNGHADDVPE---VHSAAAHATGRPSNPVTVKSDERGEFVLDHGAVVIAAVTSCTN  476

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVVNDYYD++GLWPYLEKLGFYLV
Sbjct  477  TSNPEVMLGAALLARNAVEKGLASKPWVKTTMAPGSQVVNDYYDKAGLWPYLEKLGFYLV  536

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLP+EISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV+A
Sbjct  537  GYGCTTCIGNSGPLPDEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVA  596

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTMDFDF++QPLG+DKDG +VFL+DIWPSQ+DVSDTIA+AIN EMFT+NY DVFKG
Sbjct  597  YALAGTMDFDFESQPLGKDKDGNDVFLKDIWPSQKDVSDTIASAINSEMFTKNYGDVFKG  656

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            D+RWRNLPTPSGNTFEW+P+STYVRKPPYF+GM A+PEPVG+I+GARVLALLGDSVTTDH
Sbjct  657  DERWRNLPTPSGNTFEWNPDSTYVRKPPYFDGMPAEPEPVGDITGARVLALLGDSVTTDH  716

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPA +IKPGTPAA+YLDEHGV+RKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDVSG
Sbjct  717  ISPASSIKPGTPAAQYLDEHGVERKDYNSFGSRRGNHEVMIRGTFANIRLRNMLLDDVSG  776

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  777  GYTRDFTQDGGPQAFIYDAAQNYAAQDIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  836

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA+ LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  837  AESFERIHRSNLIGMGVIPLQFPDGKSATDLGLDGTEVFDITGIEELNSGKTPKTVHVKA  896

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K  G  IEFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  897  SKDSGDPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  938


>gi|254819545|ref|ZP_05224546.1| aconitate hydratase [Mycobacterium intracellulare ATCC 13950]
Length=941

 Score = 1672 bits (4331),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 828/943 (88%), Positives = 879/943 (94%), Gaps = 11/943 (1%)

Query  6    VNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  65
            +NSFGA +TL+VG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIEAIA
Sbjct  1    MNSFGARNTLEVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIEAIA  60

Query  66   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVI  125
            NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAI +LGG+P+KVNPLAPADLVI
Sbjct  61   NWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGELGGDPEKVNPLAPADLVI  120

Query  126  DHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEY  185
            DHSVIADLFG AD+FERNVEIEYQRNGERYQFLRWGQGAF DFKVVPPGTGIVHQVNIEY
Sbjct  121  DHSVIADLFGTADSFERNVEIEYQRNGERYQFLRWGQGAFQDFKVVPPGTGIVHQVNIEY  180

Query  186  LASVVMTRDG-----VAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            LA VVM+R       VAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  181  LAKVVMSRADAQGTVVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGF+LTGEIQPGVTATDVVLTVTEMLR HGVVGKFVEFYGEGVAEVPLANRATLGNM
Sbjct  241  PRVVGFKLTGEIQPGVTATDVVLTVTEMLRHHGVVGKFVEFYGEGVAEVPLANRATLGNM  300

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFP+DEETI YLRFTGR  EQ+ALVEAYAK QGMWHDPKHEPE+SEY+EL+
Sbjct  301  SPEFGSTAAIFPVDEETISYLRFTGRKDEQLALVEAYAKEQGMWHDPKHEPEYSEYIELD  360

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LSDVVPSIAGPKRPQDRIALA AKSTFREQI  YVG+  PD     +SKLDEVV+E+FPA
Sbjct  361  LSDVVPSIAGPKRPQDRIALADAKSTFREQICDYVGD-DPDKKE--YSKLDEVVDESFPA  417

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SDPGQ T  + D   D  V SAAAH+ GRVS+PV VKSDELGEFVLDHGAVVIAA+TSCT
Sbjct  418  SDPGQATNGHAD---DHKVQSAAAHSKGRVSSPVTVKSDELGEFVLDHGAVVIAAVTSCT  474

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNPEVMLGAALLARNAVEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYL
Sbjct  475  NTSNPEVMLGAALLARNAVEKGLVSKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYL  534

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPE+ISKA+NDNDLSV AVLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  535  VGYGCTTCIGNSGPLPEDISKAINDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVI  594

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDF  QPLG+DKDG +VFL+DIWPSQ+DVSDTIA+AINQEMFT+NYADVFK
Sbjct  595  AYALAGTMDFDFDEQPLGKDKDGNDVFLKDIWPSQKDVSDTIASAINQEMFTKNYADVFK  654

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            GD+RWRNLPTPSGNTFEW+P+STYVRKPPYF+GM A+PEPV +I+GARVLALLGDSVTTD
Sbjct  655  GDERWRNLPTPSGNTFEWNPDSTYVRKPPYFDGMPAEPEPVADITGARVLALLGDSVTTD  714

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPA +IKPGTPAA+YLDEHGV+RKDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDVS
Sbjct  715  HISPASSIKPGTPAAQYLDEHGVERKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVS  774

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQ   PQAFIYDAAQNYAAQ IPLVV GGKEYGSGSSRDWAAKGT LLGVRAV
Sbjct  775  GGYTRDFTQDDAPQAFIYDAAQNYAAQDIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAV  834

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            IAESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LNDGKTPKTV V+
Sbjct  835  IAESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEALNDGKTPKTVKVK  894

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            A+K     +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  895  ASKDGSDAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  937


>gi|15827972|ref|NP_302235.1| aconitate hydratase [Mycobacterium leprae TN]
 gi|221230449|ref|YP_002503865.1| aconitate hydratase [Mycobacterium leprae Br4923]
 gi|13093525|emb|CAC30767.1| aconitate hydratase [Mycobacterium leprae]
 gi|219933556|emb|CAR71909.1| aconitate hydratase [Mycobacterium leprae Br4923]
Length=944

 Score = 1667 bits (4316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 823/948 (87%), Positives = 882/948 (94%), Gaps = 12/948 (1%)

Query  1    VTSK-SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKD  59
            ++SK SVNSF A DTLK+G+ SYQIYRLDAV NT +LPYSLKVLAENLLRNEDG NITKD
Sbjct  2    ISSKDSVNSFSARDTLKIGDNSYQIYRLDAVSNTKRLPYSLKVLAENLLRNEDGKNITKD  61

Query  60   HIEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLA  119
            HIEAIANWD +AEPSIEIQYTPAR+VMQDFTGVPCIVDLATMREAI DLGGNP+KVNPLA
Sbjct  62   HIEAIANWDRQAEPSIEIQYTPARIVMQDFTGVPCIVDLATMREAIGDLGGNPEKVNPLA  121

Query  120  PADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVH  179
              DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAF+DFKVVPPGTGIVH
Sbjct  122  RVDLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFNDFKVVPPGTGIVH  181

Query  180  QVNIEYLASVVMTRDG-----VAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQ  234
            QVNIEYLASVVMT++      VAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQ
Sbjct  182  QVNIEYLASVVMTQENTQGTVVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQ  241

Query  235  PVSMLIPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANR  294
            PVSMLIP VVGF+L+GEIQPGVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANR
Sbjct  242  PVSMLIPWVVGFKLSGEIQPGVTATDVVLTVTEMLRRHGVVGKFVEFYGEGVAEVPLANR  301

Query  295  ATLGNMSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFS  354
            ATLGNMSPEFGSTAAIFPIDEETI YLRFTGRTPEQVALVE YAK QGMWHDPK+EP FS
Sbjct  302  ATLGNMSPEFGSTAAIFPIDEETINYLRFTGRTPEQVALVEGYAKEQGMWHDPKNEPTFS  361

Query  355  EYLELNLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVV  414
            EYLELNLSDVVPSI+GPKRPQDRI LAQAKSTFR QI  YV +GS  S H+ HSKLDEVV
Sbjct  362  EYLELNLSDVVPSISGPKRPQDRICLAQAKSTFRAQIPKYV-DGS--SLHNQHSKLDEVV  418

Query  415  EETFPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIA  474
            EET PASDPG+L+F N+D   +  + SAAAHA+GRVSNPVR+K+ ELGEFVLDHGAVVIA
Sbjct  419  EETCPASDPGKLSFTNND---EVVMQSAAAHANGRVSNPVRIKTQELGEFVLDHGAVVIA  475

Query  475  AITSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLE  534
            AITSCTNTSNPEVML AALLARNAVEKGL SKPWVKTT+APGSQVVNDYYDRSGLWPYLE
Sbjct  476  AITSCTNTSNPEVMLCAALLARNAVEKGLASKPWVKTTMAPGSQVVNDYYDRSGLWPYLE  535

Query  535  KLGFYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLA  594
            KLGFYLVGYGCTTCIGNSGPLPEEISKA+N N+LSVTAVLSGNRNFEGRINPDVKMNYLA
Sbjct  536  KLGFYLVGYGCTTCIGNSGPLPEEISKAINYNNLSVTAVLSGNRNFEGRINPDVKMNYLA  595

Query  595  SPPLVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRN  654
            SPPLVIAYALAGTMDFDF++QPL  DK+GK V+L+DIWPSQ+DV+DTIA+AINQEMFT+N
Sbjct  596  SPPLVIAYALAGTMDFDFESQPLDTDKNGKAVYLKDIWPSQKDVTDTIASAINQEMFTKN  655

Query  655  YADVFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLG  714
            YADVFKGD+RWRNLPTPSGNTF+W+ NSTYVRKPPYFEGM+ +P+PV NI+GARVLALL 
Sbjct  656  YADVFKGDERWRNLPTPSGNTFDWEQNSTYVRKPPYFEGMSVEPKPVRNITGARVLALLD  715

Query  715  DSVTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQ  774
            DSVTTDHISPA  IKPGTPAA+YLD HGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRN 
Sbjct  716  DSVTTDHISPASTIKPGTPAAQYLDTHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNM  775

Query  775  LLDDVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLL  834
            LL+ V+GGYTRDFT+PG PQAFIYDAAQNYAA++IPLVV  GKEYGSGSSRDWAAKGTLL
Sbjct  776  LLNGVAGGYTRDFTKPGAPQAFIYDAAQNYAAENIPLVVLSGKEYGSGSSRDWAAKGTLL  835

Query  835  LGVRAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTP  894
            LGVRAVIAESFERIHRSNLIGMGVIPLQFP+G+SASSLGLDGTEVF+I GIDV N+GKTP
Sbjct  836  LGVRAVIAESFERIHRSNLIGMGVIPLQFPQGESASSLGLDGTEVFEINGIDVFNNGKTP  895

Query  895  KTVCVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            KTV V+A+K  G T+ FDA+VRIDTPGEADYYRNGGIL YVLRNILKS
Sbjct  896  KTVHVKASKASGTTVTFDALVRIDTPGEADYYRNGGILHYVLRNILKS  943


>gi|315444585|ref|YP_004077464.1| aconitase [Mycobacterium sp. Spyr1]
 gi|315262888|gb|ADT99629.1| aconitase [Mycobacterium sp. Spyr1]
Length=941

 Score = 1599 bits (4141),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 787/945 (84%), Positives = 861/945 (92%), Gaps = 13/945 (1%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + S+NSFGA DTLKVG+ SY+IYRLDAVP T KLPYSLKVLAENLLR EDG+NITKDHIE
Sbjct  5    NSSLNSFGAKDTLKVGDNSYEIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIE  64

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA WDP A+PS+EIQ+TPARV+MQDFTGVPCIVDLATMREA+ +LGG+P +VNPLAPAD
Sbjct  65   AIAKWDPSADPSVEIQFTPARVIMQDFTGVPCIVDLATMREAVGELGGDPQQVNPLAPAD  124

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFGRADAFERNVEIEY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  125  LVIDHSVIADLFGRADAFERNVEIEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  184

Query  183  IEYLASVVMTR-----DGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVS  237
            IEYLASVVM R     + VAYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVS
Sbjct  185  IEYLASVVMARSDAEGNTVAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVS  244

Query  238  MLIPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATL  297
            MLIPRVVGF++TGE +PGVTATDVVLTVTEMLRQHGVVGKFVEFYG+GVAEVPLANRATL
Sbjct  245  MLIPRVVGFKITGERRPGVTATDVVLTVTEMLRQHGVVGKFVEFYGDGVAEVPLANRATL  304

Query  298  GNMSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYL  357
            GNMSPEFGSTAAIFPID+ TI+YLR TGR+ EQ+ALVEAYAK QGMWHDP  EP+FSEYL
Sbjct  305  GNMSPEFGSTAAIFPIDDVTIEYLRLTGRSEEQLALVEAYAKEQGMWHDPSREPKFSEYL  364

Query  358  ELNLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEET  417
            EL+L+DVVPSIAGPKRPQDRIAL  AK+ FR+ I++YV N +P     P +KLD+ +++T
Sbjct  365  ELDLADVVPSIAGPKRPQDRIALDDAKNAFRKDIHNYVENNNPA----PETKLDDTIDDT  420

Query  418  FPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAIT  477
            FPASDP  L FA+D       +HSAA  ADGR + PV VKSDE GEFVLDHGAVVIAAIT
Sbjct  421  FPASDPATLQFADDGAVN---MHSAANGADGRPTKPVTVKSDEHGEFVLDHGAVVIAAIT  477

Query  478  SCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLG  537
            SCTNTSNPEVM+GAALLA+NAV+KGL  KPWVKTT+APGSQVV DYY+++GLWPYLEKLG
Sbjct  478  SCTNTSNPEVMIGAALLAKNAVDKGLARKPWVKTTMAPGSQVVTDYYNKAGLWPYLEKLG  537

Query  538  FYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP  597
            F+LVGYGCTTCIGNSGPLPEE+SKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP
Sbjct  538  FFLVGYGCTTCIGNSGPLPEEVSKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP  597

Query  598  LVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYAD  657
            LVIAYALAG+MDFDF++  LG D DG  VFL+DIWPSQ+D+SDTIA AI+QEMFT+NYAD
Sbjct  598  LVIAYALAGSMDFDFESDSLGNDSDGNPVFLKDIWPSQKDISDTIAEAISQEMFTKNYAD  657

Query  658  VFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSV  717
            VFKGD+RWRNLPTPSGNTFEWD +STYVRKPPYFEGM A+P+PV +ISGARVLALLGDSV
Sbjct  658  VFKGDERWRNLPTPSGNTFEWDQDSTYVRKPPYFEGMPAEPQPVTDISGARVLALLGDSV  717

Query  718  TTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLD  777
            TTDHISPAGAIKPGTPAA YL+ HGV+RKDYNS+GSRRGNHEVMIRGTFANIRL+NQLLD
Sbjct  718  TTDHISPAGAIKPGTPAAEYLESHGVERKDYNSYGSRRGNHEVMIRGTFANIRLKNQLLD  777

Query  778  DVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGV  837
            DVSGGYTRDFT+  G QAFIYDAAQNYA Q+IPLVV GGKEYGSGSSRDWAAKGT LLGV
Sbjct  778  DVSGGYTRDFTKE-GEQAFIYDAAQNYAEQNIPLVVLGGKEYGSGSSRDWAAKGTSLLGV  836

Query  838  RAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTV  897
            RAVI ESFERIHRSNLIGMGVIPLQFPEG+SA+SL LDGTE FDITGI+ LN+GKTPKTV
Sbjct  837  RAVITESFERIHRSNLIGMGVIPLQFPEGESAASLKLDGTETFDITGIEELNNGKTPKTV  896

Query  898  CVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             V ATK DG  +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  897  KVTATKPDGGKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  941


>gi|126435070|ref|YP_001070761.1| aconitate hydratase [Mycobacterium sp. JLS]
 gi|126234870|gb|ABN98270.1| aconitase [Mycobacterium sp. JLS]
Length=937

 Score = 1599 bits (4140),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 788/938 (85%), Positives = 859/938 (92%), Gaps = 8/938 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSF A DTL VG+KSY+IYRLDAVP T KLPYSLKVLAENLLR EDG+NITKDHIEAI
Sbjct  7    SINSFDARDTLTVGDKSYEIYRLDAVPGTDKLPYSLKVLAENLLRTEDGANITKDHIEAI  66

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP+A+PSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+ DLGG+P KVNPLAPADLV
Sbjct  67   ANWDPEADPSIEIQFTPARVIMQDFTGVPCIVDLATMREAVGDLGGDPQKVNPLAPADLV  126

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVIADLFG A+AFERNVEIEY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  127  IDHSVIADLFGTANAFERNVEIEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  186

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLASVVM RDGVAYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  187  YLASVVMERDGVAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  246

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGE + GVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF
Sbjct  247  GFKLTGERRAGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  306

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPID+ TI YLR TGR+ EQ+ALVEAYAK QGMWHDP  EP+FSEY+EL+LSDV
Sbjct  307  GSTAAIFPIDDVTIDYLRMTGRSDEQLALVEAYAKEQGMWHDPSREPKFSEYIELDLSDV  366

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSIAGPKRPQDRIAL  AKS FR+ I++YV NG+  +    HS +DE VEETFP SDP 
Sbjct  367  VPSIAGPKRPQDRIALDDAKSAFRKDIHNYVENGNSAA----HSNVDEAVEETFPGSDPV  422

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             L+FA +D      V SAA  A+GR + PV VKSDE GEFV+DHGAVVIAAITSCTNTSN
Sbjct  423  SLSFAEEDAV---EVVSAANGAEGRPTKPVTVKSDERGEFVIDHGAVVIAAITSCTNTSN  479

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            PEVM+GAALLA+NAVEKGLTSKPWVKTT+APGSQVV DYY+++GLWPYLEKLGF+LVGYG
Sbjct  480  PEVMIGAALLAKNAVEKGLTSKPWVKTTMAPGSQVVTDYYEKAGLWPYLEKLGFFLVGYG  539

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL
Sbjct  540  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  599

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AG+MDFDF+   LG D+DG  VFL+DIWPSQQD++DTIA+AIN EMF +NYADVFKGD+R
Sbjct  600  AGSMDFDFENDCLGTDEDGNPVFLKDIWPSQQDINDTIASAINTEMFKKNYADVFKGDER  659

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WRNLPTPSG+TFEW  +STYVRKPPYF+GM A+P+PV +I+GARVLALLGDSVTTDHISP
Sbjct  660  WRNLPTPSGDTFEWADDSTYVRKPPYFDGMPAEPQPVSDITGARVLALLGDSVTTDHISP  719

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG+IKPGTPAA+YL+ HGV++KDYNS+GSRRGNHEVMIRGTFANIRL+NQLLDDVSGGYT
Sbjct  720  AGSIKPGTPAAQYLESHGVEKKDYNSYGSRRGNHEVMIRGTFANIRLKNQLLDDVSGGYT  779

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFT  GG QAFIYDAAQNYA Q IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI ES
Sbjct  780  RDFTN-GGEQAFIYDAAQNYAEQDIPLVVLGGKEYGSGSSRDWAAKGTSLLGVRAVITES  838

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFPEG+SA+SL LDGTE FDITGI+ LN+GKTPKTV V+A+K 
Sbjct  839  FERIHRSNLIGMGVIPLQFPEGESAASLKLDGTETFDITGIEALNEGKTPKTVHVKASKE  898

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             G T+EFDAVVRIDTPGEADYYRNGGILQYVLRN+LK+
Sbjct  899  GGETVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKT  936


>gi|145224249|ref|YP_001134927.1| aconitate hydratase [Mycobacterium gilvum PYR-GCK]
 gi|145216735|gb|ABP46139.1| aconitase [Mycobacterium gilvum PYR-GCK]
Length=941

 Score = 1596 bits (4132),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 786/945 (84%), Positives = 859/945 (91%), Gaps = 13/945 (1%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + S+NSFGA DTLKVG+ SY+IYRLDAVP T KLPYSLKVLAENLLR EDG+NITKDHIE
Sbjct  5    NSSLNSFGAKDTLKVGDNSYEIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIE  64

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA WDP A+PS+EIQ+TPARV+MQDFTGVPCIVDLATMREA+ +LGG+P +VNPLAPAD
Sbjct  65   AIAKWDPSADPSVEIQFTPARVIMQDFTGVPCIVDLATMREAVGELGGDPQQVNPLAPAD  124

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFGRADAFERNVEIEY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  125  LVIDHSVIADLFGRADAFERNVEIEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  184

Query  183  IEYLASVVMTR-----DGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVS  237
            IEYLASVVM R     + VAYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVS
Sbjct  185  IEYLASVVMARSDAEGNTVAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVS  244

Query  238  MLIPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATL  297
            MLIPRVVGF++TGE +PGVTATDVVLTVTEMLRQHGVVGKFVEFYG+GV EVPLANRATL
Sbjct  245  MLIPRVVGFKITGERRPGVTATDVVLTVTEMLRQHGVVGKFVEFYGDGVDEVPLANRATL  304

Query  298  GNMSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYL  357
            GNMSPEFGSTAAIFPID+ TI+YLR TGR+ EQ+ALVEAYAK QGMWHDP  EP+FSEYL
Sbjct  305  GNMSPEFGSTAAIFPIDDVTIEYLRLTGRSEEQLALVEAYAKEQGMWHDPSREPKFSEYL  364

Query  358  ELNLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEET  417
            EL+L+DVVPSIAGPKRPQDRIAL  AK+ FR+ I++YV N  P     P +KLD+ +++T
Sbjct  365  ELDLADVVPSIAGPKRPQDRIALDDAKNAFRKDIHNYVENNHPA----PETKLDDTIDDT  420

Query  418  FPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAIT  477
            FPASDP  L FA+D       +HSAA  ADGR + PV VKSDE GEFVLDHGAVVIAAIT
Sbjct  421  FPASDPATLQFADDGAVN---MHSAANGADGRPTKPVTVKSDEHGEFVLDHGAVVIAAIT  477

Query  478  SCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLG  537
            SCTNTSNPEVM+GAALLA+NAV+KGL  KPWVKTT+APGSQVV DYY+++GLWPYLEKLG
Sbjct  478  SCTNTSNPEVMIGAALLAKNAVDKGLARKPWVKTTMAPGSQVVTDYYNKAGLWPYLEKLG  537

Query  538  FYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP  597
            F+LVGYGCTTCIGNSGPLPEE+SKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP
Sbjct  538  FFLVGYGCTTCIGNSGPLPEEVSKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP  597

Query  598  LVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYAD  657
            LVIAYALAG+MDFDF++  LG D DG  VFL+DIWPSQ+D+SDTIA AI+QEMFT+NYAD
Sbjct  598  LVIAYALAGSMDFDFESDSLGNDSDGNPVFLKDIWPSQKDISDTIAEAISQEMFTKNYAD  657

Query  658  VFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSV  717
            VFKGD+RWRNLPTPSGNTFEWD +STYVRKPPYFEGM A+P+PV +ISGARVLALLGDSV
Sbjct  658  VFKGDERWRNLPTPSGNTFEWDQDSTYVRKPPYFEGMPAEPQPVTDISGARVLALLGDSV  717

Query  718  TTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLD  777
            TTDHISPAGAIKPGTPAA YL+ HGV+RKDYNS+GSRRGNHEVMIRGTFANIRL+NQLLD
Sbjct  718  TTDHISPAGAIKPGTPAAEYLESHGVERKDYNSYGSRRGNHEVMIRGTFANIRLKNQLLD  777

Query  778  DVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGV  837
            DVSGGYTRDFT+  G QAFIYDAAQNYA Q+IPLVV GGKEYGSGSSRDWAAKGT LLGV
Sbjct  778  DVSGGYTRDFTKE-GEQAFIYDAAQNYAEQNIPLVVLGGKEYGSGSSRDWAAKGTSLLGV  836

Query  838  RAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTV  897
            RAVI ESFERIHRSNLIGMGVIPLQFPEG+SA+SL LDGTE FDITGI+ LN+GKTPKTV
Sbjct  837  RAVITESFERIHRSNLIGMGVIPLQFPEGESAASLKLDGTETFDITGIEELNNGKTPKTV  896

Query  898  CVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             V ATK DG  +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  897  KVTATKPDGGKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  941


>gi|108799416|ref|YP_639613.1| aconitate hydratase [Mycobacterium sp. MCS]
 gi|119868529|ref|YP_938481.1| aconitate hydratase [Mycobacterium sp. KMS]
 gi|108769835|gb|ABG08557.1| aconitase [Mycobacterium sp. MCS]
 gi|119694618|gb|ABL91691.1| aconitase [Mycobacterium sp. KMS]
Length=942

 Score = 1585 bits (4105),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/943 (84%), Positives = 858/943 (91%), Gaps = 13/943 (1%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSF A DTL VG+KSY+IYRLDAVP T KLPYSLKVLAENLLR EDG+NITKDHIEAI
Sbjct  7    SINSFDARDTLTVGDKSYEIYRLDAVPGTDKLPYSLKVLAENLLRTEDGANITKDHIEAI  66

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP+A+PSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+ DLGG+P KVNPLAPADLV
Sbjct  67   ANWDPEADPSIEIQFTPARVIMQDFTGVPCIVDLATMREAVGDLGGDPQKVNPLAPADLV  126

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVIADLFG A+AFERNVEIEY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  127  IDHSVIADLFGTANAFERNVEIEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  186

Query  185  YLASVVMTR---DG--VAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSML  239
            YLASVVM R   DG  VAYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSML
Sbjct  187  YLASVVMARSDADGNTVAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSML  246

Query  240  IPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGN  299
            IPRVVGF+LTGE + GVTATDVVLTVTEMLR+HGVVGKFVEFYGEGVAEVPLANRATLGN
Sbjct  247  IPRVVGFKLTGERRAGVTATDVVLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGN  306

Query  300  MSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLEL  359
            MSPEFGSTAAIFPID+ TI YLR TGR+ EQ+ALVEAYAK QGMWHDP  EP+FSEY+EL
Sbjct  307  MSPEFGSTAAIFPIDDVTIDYLRMTGRSDEQLALVEAYAKEQGMWHDPSREPKFSEYIEL  366

Query  360  NLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFP  419
            +LSDVVPSIAGPKRPQDRIAL  AKS FR+ I++YV NG+  +    HS +DE VEETFP
Sbjct  367  DLSDVVPSIAGPKRPQDRIALDDAKSAFRKDIHNYVENGNSAA----HSNVDEAVEETFP  422

Query  420  ASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSC  479
             SDP  L+FA +       V SAA  A+GR + P+ VKSDE GEFV+DHGAVVIAAITSC
Sbjct  423  GSDPVSLSFAEESAVE---VVSAANGAEGRPTKPITVKSDERGEFVIDHGAVVIAAITSC  479

Query  480  TNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFY  539
            TNTSNPEVM+GAALLA+NAVEKGLTSKPWVKTT+APGSQVV +YY+++GLWPYLEKLGF+
Sbjct  480  TNTSNPEVMIGAALLAKNAVEKGLTSKPWVKTTMAPGSQVVTEYYEKAGLWPYLEKLGFF  539

Query  540  LVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV  599
            LVGYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV
Sbjct  540  LVGYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV  599

Query  600  IAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVF  659
            IAYALAG+MDFDF+   LG D+DG  VFL+DIWPSQQD++DTIA+AIN EMF +NYADVF
Sbjct  600  IAYALAGSMDFDFENDCLGTDEDGNPVFLKDIWPSQQDINDTIASAINTEMFKKNYADVF  659

Query  660  KGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTT  719
            KGD+RWRNLPTPSG+TFEW  +STYVRKPPYF+GM A+P+PV +I+GARVLALLGDSVTT
Sbjct  660  KGDERWRNLPTPSGDTFEWADDSTYVRKPPYFDGMPAEPQPVSDITGARVLALLGDSVTT  719

Query  720  DHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDV  779
            DHISPAG+IKPGTPAA+YL+ HGV++KDYNS+GSRRGNHEVMIRGTFANIRL+NQLLDDV
Sbjct  720  DHISPAGSIKPGTPAAQYLESHGVEKKDYNSYGSRRGNHEVMIRGTFANIRLKNQLLDDV  779

Query  780  SGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRA  839
            SGGYTRDFT  GG QAFIYDAAQNYA Q IPLVV GGKEYGSGSSRDWAAKGT LLGVRA
Sbjct  780  SGGYTRDFTN-GGEQAFIYDAAQNYAEQDIPLVVLGGKEYGSGSSRDWAAKGTSLLGVRA  838

Query  840  VIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCV  899
            VI ESFERIHRSNLIGMGVIPLQFPEG+SA+SL LDGTE FDITGI+ LN+GKTPKTV V
Sbjct  839  VITESFERIHRSNLIGMGVIPLQFPEGESAASLKLDGTETFDITGIEALNEGKTPKTVHV  898

Query  900  QATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            +A+K  G T+EFDAVVRIDTPGEADYYRNGGILQYVLRN+LK+
Sbjct  899  KASKEGGETVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKT  941


>gi|118471676|ref|YP_887458.1| aconitate hydratase 1 [Mycobacterium smegmatis str. MC2 155]
 gi|302595583|sp|A0QX20.1|ACON_MYCS2 RecName: Full=Aconitate hydratase
 gi|116266940|gb|ABJ96316.1| putatice aconitate hydratase [Mycobacterium smegmatis str. MC2 
155]
 gi|118172963|gb|ABK73859.1| aconitate hydratase 1 [Mycobacterium smegmatis str. MC2 155]
Length=943

 Score = 1568 bits (4061),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 767/938 (82%), Positives = 847/938 (91%), Gaps = 6/938 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSFGA DTL VG++SY+IYRL+AVP T KLPYSLKVLAENLLR EDG+NITKDHIEAI
Sbjct  10   SLNSFGARDTLTVGDQSYEIYRLNAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIEAI  69

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP AEPSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+A LGG+P+KVNPLAPA+LV
Sbjct  70   ANWDPNAEPSIEIQFTPARVIMQDFTGVPCIVDLATMREAVAALGGDPNKVNPLAPAELV  129

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FG A AFERNVE+EY+RN ERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  130  IDHSVILDVFGNASAFERNVELEYERNAERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  189

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLA  VM RDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  190  YLARTVMVRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  249

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+L+GEI+PGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSPEF
Sbjct  250  GFKLSGEIKPGVTATDVVLTVTDMLRRHGVVGKFVEFYGKGVAEVPLANRATLGNMSPEF  309

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPIDEETI YLR TGRT EQ+ALVEAYAKAQGMWHDP+ EP FSEYLEL+LS V
Sbjct  310  GSTAAIFPIDEETINYLRLTGRTDEQLALVEAYAKAQGMWHDPEREPVFSEYLELDLSTV  369

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSI+GPKRPQDRI L  AK+ FR+ I++YV    P     P +KLDE VEE+FPASDP 
Sbjct  370  VPSISGPKRPQDRIELTDAKNAFRKDIHNYVEQNHPT----PETKLDEAVEESFPASDPV  425

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             L+FA+D     +   SAA  A GR +NPV V S+E G+FVLDHGAVV+A ITSCTNTSN
Sbjct  426  SLSFADD--GAPDMRPSAANGATGRPTNPVLVHSEERGDFVLDHGAVVVAGITSCTNTSN  483

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLA+ AVEKGLT+KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL GYG
Sbjct  484  PSVMLGAALLAKKAVEKGLTTKPWVKTNMAPGSQVVTDYYNKAGLWPYLEKLGYYLGGYG  543

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGN+GPLPEEISKA+NDNDL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY +
Sbjct  544  CTTCIGNTGPLPEEISKAINDNDLAVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYGI  603

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF++ PLGQD +G +VFLRDIWPS  ++ +TIA++IN+EMFT +YADVFKGDDR
Sbjct  604  AGTMDFDFESDPLGQDSEGNDVFLRDIWPSAAEIEETIASSINREMFTESYADVFKGDDR  663

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WR+LPTP G+TFEWDP STYVRK PYF+GM A+PEPV +I GARVLALLGDSVTTDHISP
Sbjct  664  WRSLPTPEGDTFEWDPASTYVRKAPYFDGMPAEPEPVSDIKGARVLALLGDSVTTDHISP  723

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AGAIKPGTPAA+YLD +GV+RKDYNS GSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT
Sbjct  724  AGAIKPGTPAAQYLDANGVERKDYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  783

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQPGGPQAFIYDA++NY    IPLVV GGKEYGSGSSRDWAAKGT+LLGV+AVI ES
Sbjct  784  RDFTQPGGPQAFIYDASENYKKAGIPLVVLGGKEYGSGSSRDWAAKGTVLLGVKAVITES  843

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP G+SA+SL LDGTE +DI GI+ LN GKTPKTV V ATK 
Sbjct  844  FERIHRSNLIGMGVIPLQFPAGESAASLKLDGTETYDIEGIEELNSGKTPKTVHVTATKE  903

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            DG+ +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  904  DGSKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  941


>gi|333990879|ref|YP_004523493.1| aconitate hydratase Acn [Mycobacterium sp. JDM601]
 gi|333486847|gb|AEF36239.1| aconitate hydratase Acn [Mycobacterium sp. JDM601]
Length=940

 Score = 1568 bits (4059),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 773/947 (82%), Positives = 849/947 (90%), Gaps = 13/947 (1%)

Query  1    VTSK-SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKD  59
            +TSK S+NSFGA DTLKVG+  YQIYRLDAVP T KLPYSLKVLAENLLR EDG+NITKD
Sbjct  1    MTSKDSLNSFGASDTLKVGDDEYQIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKD  60

Query  60   HIEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLA  119
            HI AIANWDP AEPS+EIQ+TPARVVMQDFTGVPCIVDLATMREA+A LGG+P+KVNPLA
Sbjct  61   HINAIANWDPAAEPSVEIQFTPARVVMQDFTGVPCIVDLATMREAVAALGGDPEKVNPLA  120

Query  120  PADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVH  179
            PA+LVIDHSVI D+FGRADAFERNVE+EYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVH
Sbjct  121  PAELVIDHSVILDVFGRADAFERNVELEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVH  180

Query  180  QVNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSML  239
            QVNIEYLA  VM RDG+AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSML
Sbjct  181  QVNIEYLARTVMVRDGIAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSML  240

Query  240  IPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGN  299
            IPRVVGF+LTGEI+PGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGN
Sbjct  241  IPRVVGFKLTGEIKPGVTATDVVLTVTDMLRRHGVVGKFVEFYGKGVAEVPLANRATLGN  300

Query  300  MSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLEL  359
            MSPEFGSTAAIFPID+ETI YLR TGR+ +Q+ALVEAYAK QGMWHDP  EP +SEY+EL
Sbjct  301  MSPEFGSTAAIFPIDDETINYLRLTGRSEQQLALVEAYAKTQGMWHDPAREPAYSEYIEL  360

Query  360  NLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFP  419
            +L  VVPSIAGPKRPQDRI L+ AK+ FR+ I++YVG  S      PHS+LDE V E+FP
Sbjct  361  DLGTVVPSIAGPKRPQDRIELSDAKTAFRKDIHNYVGEDS----DAPHSQLDEAVAESFP  416

Query  420  ASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSC  479
            ASDP  L+FA+DD A    V SAA   DGR S PV+V S E G+FVLDHGAVV+A ITSC
Sbjct  417  ASDPAVLSFADDDAA----VPSAAQDCDGRPSKPVKVSSAERGDFVLDHGAVVVAGITSC  472

Query  480  TNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFY  539
            TNTSNPEVMLGAALLAR AVEKGLTSKPWVKT +APGSQVV DYY+++GLWPYLEKLGFY
Sbjct  473  TNTSNPEVMLGAALLARKAVEKGLTSKPWVKTNMAPGSQVVTDYYNKAGLWPYLEKLGFY  532

Query  540  LVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLV  599
            L GYGCTTCIGN+GPLPEEISKA+NDNDLSVTAVLSGNRNFEGRI PDVKMNYLASPPLV
Sbjct  533  LGGYGCTTCIGNTGPLPEEISKAINDNDLSVTAVLSGNRNFEGRIQPDVKMNYLASPPLV  592

Query  600  IAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVF  659
            IAYA+AGTMDFDF+TQPLG+D +G +VFL+DIWPS  ++ +TIA++I+++MFT++YADVF
Sbjct  593  IAYAIAGTMDFDFETQPLGRDSEGNDVFLKDIWPSTAEIQETIASSIDRDMFTKSYADVF  652

Query  660  KGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTT  719
             GD+RWR+LPTP GNTF WD  STYVRK PYF+GM A+P PV +I+GARVLALLGDSVTT
Sbjct  653  SGDERWRSLPTPEGNTFAWDEKSTYVRKAPYFDGMPAEPAPVADITGARVLALLGDSVTT  712

Query  720  DHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDV  779
            DHISPAGAIK GTPAA+YL+ +GV  +DYNS GSRRGNHEVMIRGTFANIRLRNQLLDDV
Sbjct  713  DHISPAGAIKKGTPAAQYLEANGVSPRDYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDV  772

Query  780  SGGYTRDFTQPG----GPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLL  835
            SGGYTRDFTQ       PQAFI+DAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LL
Sbjct  773  SGGYTRDFTQSDENGESPQAFIFDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTALL  832

Query  836  GVRAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPK  895
            GVRAVI ESFERIHRSNLIGMGVIPLQFP G+SA+SL LDGTEVFDITGI+ LN GKTPK
Sbjct  833  GVRAVITESFERIHRSNLIGMGVIPLQFPAGESAASLKLDGTEVFDITGIEELNTGKTPK  892

Query  896  TVCVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            TV V ATK DG+   FDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  893  TVKVTATKADGSRTVFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  939


>gi|120403729|ref|YP_953558.1| aconitate hydratase 1 [Mycobacterium vanbaalenii PYR-1]
 gi|119956547|gb|ABM13552.1| aconitate hydratase 1 [Mycobacterium vanbaalenii PYR-1]
Length=954

 Score = 1540 bits (3988),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 768/956 (81%), Positives = 842/956 (89%), Gaps = 22/956 (2%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + S+NS+GA DTLKVG+ SY+IYRLDAVP T KLPYSLKVLAENLLR EDG+NITKDHIE
Sbjct  5    NSSLNSYGAKDTLKVGDNSYEIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIE  64

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDP+AEPSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+A LGG+P KVNPL+PA+
Sbjct  65   AIANWDPEAEPSIEIQFTPARVLMQDFTGVPCIVDLATMREAVAALGGDPAKVNPLSPAE  124

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FGRADAFERNVE+EY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  125  MVIDHSVILDVFGRADAFERNVELEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  184

Query  183  IEYLASVVMTRD-----------GVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAM  231
            IEYLA VVM RD            VAYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAM
Sbjct  185  IEYLARVVMVRDRAGEAGEGDSISVAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAM  244

Query  232  LGQPVSMLIPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPL  291
            LGQPVSMLIPRVVGF+LTGEI+PGVTATDVVLTVT+MLR+HGVVGKFVEFYG GVAEVPL
Sbjct  245  LGQPVSMLIPRVVGFKLTGEIKPGVTATDVVLTVTDMLRKHGVVGKFVEFYGNGVAEVPL  304

Query  292  ANRATLGNMSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEP  351
            ANRATLGNMSPEFGSTAA+FPIDEETI YLR TGRT EQ+ALVEAYAK QGMWHDP  EP
Sbjct  305  ANRATLGNMSPEFGSTAAMFPIDEETINYLRLTGRTDEQLALVEAYAKEQGMWHDPAKEP  364

Query  352  EFSEYLELNLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLD  411
             FSEYLEL+LS VVPSIAGPKRPQDRI L  AK+ FR+ I++YV    P     P +KLD
Sbjct  365  VFSEYLELDLSTVVPSIAGPKRPQDRIELTDAKNAFRKDIHNYVEENHPT----PETKLD  420

Query  412  EVVEETFPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAV  471
            E VEE+FPASD   L+FA DD A D    SAA  A GR S PV VKS E GEFVLDHGAV
Sbjct  421  EAVEESFPASDSVSLSFA-DDGAVDAR-PSAANGATGRPSKPVTVKSAERGEFVLDHGAV  478

Query  472  VIAAITSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWP  531
            V+A ITSCTNTSNP VMLGAALLA+ AVEKGL++KPWVKT +APGSQVV DYY+++GLWP
Sbjct  479  VVAGITSCTNTSNPSVMLGAALLAKKAVEKGLSTKPWVKTNMAPGSQVVTDYYNKAGLWP  538

Query  532  YLEKLGFYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMN  591
            YLEKLG+YL GYGCTTCIGN+GPLP+EIS A+NDNDLSVTAVLSGNRNFEGRI+PDVKMN
Sbjct  539  YLEKLGYYLGGYGCTTCIGNTGPLPDEISAAINDNDLSVTAVLSGNRNFEGRISPDVKMN  598

Query  592  YLASPPLVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMF  651
            YLASPPLVIAY LAGTMDFDF+  PLGQD DG +VFL+DIWPS  ++ +TI ++IN+EMF
Sbjct  599  YLASPPLVIAYGLAGTMDFDFEADPLGQDGDGNDVFLKDIWPSAAEIQETITSSINREMF  658

Query  652  TRNYADVFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLA  711
              +YADVFKGD+RWR+LPTP GNTFEWD +STYVRK PYF+GM A+PEPV +I GARVLA
Sbjct  659  ADSYADVFKGDERWRSLPTPEGNTFEWDEDSTYVRKAPYFDGMPAEPEPVKDIKGARVLA  718

Query  712  LLGDSVTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRL  771
            LLGDSVTTDHISPAG+IK GTPAA+YL+EHGV+ KD+NS GSRRGNHEVMIRGTFANIRL
Sbjct  719  LLGDSVTTDHISPAGSIKKGTPAAQYLEEHGVEPKDFNSLGSRRGNHEVMIRGTFANIRL  778

Query  772  RNQLLDDVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKG  831
            RNQLLDDVSGGYTRDFTQ GGPQAFIYDAAQNYA + IPLVV GGKEYGSGSSRDWAAKG
Sbjct  779  RNQLLDDVSGGYTRDFTQDGGPQAFIYDAAQNYAKEGIPLVVLGGKEYGSGSSRDWAAKG  838

Query  832  TLLLGVRAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDG  891
            T LLGVRAVI ESFERIHRSNLIGMGVIPLQFP+G+SA+SL LDGTE FDI GI+ LN+G
Sbjct  839  TTLLGVRAVITESFERIHRSNLIGMGVIPLQFPKGESAASLKLDGTETFDIEGIEALNEG  898

Query  892  KTPKTVCVQATK--GDG---ATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            KTPKTV V A K   DG   + +EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKS
Sbjct  899  KTPKTVKVTAKKIAEDGTVSSAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS  954


>gi|296393883|ref|YP_003658767.1| aconitate hydratase 1 [Segniliparus rotundus DSM 44985]
 gi|296181030|gb|ADG97936.1| aconitate hydratase 1 [Segniliparus rotundus DSM 44985]
Length=935

 Score = 1532 bits (3967),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 743/938 (80%), Positives = 835/938 (90%), Gaps = 7/938 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSF + DTLKV ++ Y+I+RLD V   +KLPY LKVLAENLLR EDG+NIT+DHI A+
Sbjct  3    SINSFNSRDTLKVDDQEYEIFRLDRVEGLSKLPYCLKVLAENLLRTEDGANITRDHINAL  62

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP AEPS+EIQ+TPARV+MQDFTGVPC+VDLATMREA+ +LGG+PDKVNPL+PA+LV
Sbjct  63   ANWDPSAEPSVEIQFTPARVIMQDFTGVPCVVDLATMREAVTELGGDPDKVNPLSPAELV  122

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FGRADAFERNVE+EY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  123  IDHSVILDVFGRADAFERNVELEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  182

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLA  V TR G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  183  YLARTVFTRGGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  242

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTG I PGVTATDVVLT+TE+LR+HGVVGKFVEFYG GVAEVPLANRATLGNMSPEF
Sbjct  243  GFKLTGSINPGVTATDVVLTITEILRKHGVVGKFVEFYGAGVAEVPLANRATLGNMSPEF  302

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPID ETI YLR TGR   Q+ALVEAYAK QG+WHD  HEP +SEYLELNLS+V
Sbjct  303  GSTAAIFPIDGETIDYLRLTGRDEHQLALVEAYAKEQGLWHDAAHEPAYSEYLELNLSEV  362

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSIAGPKRPQDRI L+++K  FR+ I++YVG+ +P     PH++LDE +EE+FPASDP 
Sbjct  363  VPSIAGPKRPQDRILLSESKVAFRKDIHNYVGDEAPA----PHTQLDEAIEESFPASDPA  418

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
            +L+FA DD      V SAA   +GR S PVRVKS+E GEF+LDHGAV +A ITSCTNTSN
Sbjct  419  RLSFAEDDAVP---VLSAATGCEGRPSKPVRVKSEERGEFILDHGAVAVAGITSCTNTSN  475

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLA+NAVEKGLTSKPWVKT +APGSQVV DYY+++GLWPYLEKLGFYL GYG
Sbjct  476  PSVMLGAALLAKNAVEKGLTSKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGFYLGGYG  535

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGN+GPLPEEIS+AVNDNDL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAYAL
Sbjct  536  CTTCIGNTGPLPEEISQAVNDNDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYAL  595

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+ +PLG   DG+ VFL+DIWPS +D+ DTI A I++EMFT++YADVFKGD+R
Sbjct  596  AGTMDFDFEHEPLGTGTDGQPVFLKDIWPSAKDIEDTIKATIDREMFTKSYADVFKGDER  655

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WR+LPTP GNTFEW  +STYVRK PYF+GM  +P PV +I GARVLALLGDSVTTDHISP
Sbjct  656  WRSLPTPEGNTFEWSDSSTYVRKAPYFDGMPLEPAPVADIKGARVLALLGDSVTTDHISP  715

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG+IKPGTPAA+YLD HGV + DYNS GSRRGNHEVM+RGTFANIRL+NQLLD VSGGYT
Sbjct  716  AGSIKPGTPAAQYLDSHGVAQADYNSLGSRRGNHEVMVRGTFANIRLQNQLLDGVSGGYT  775

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQPGGPQ+FIYDA+ NY    IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI ES
Sbjct  776  RDFTQPGGPQSFIYDASVNYQKAGIPLVVLGGKEYGSGSSRDWAAKGTTLLGVRAVITES  835

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP+G+SA SL L+GTEVFDI+GI+ LN+G TPKTV V AT+ 
Sbjct  836  FERIHRSNLIGMGVIPLQFPKGESAQSLKLNGTEVFDISGIEKLNEGVTPKTVHVTATRE  895

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            DG+ +EFDAVVRIDTPGEADYYRNGGILQYVLRN+++S
Sbjct  896  DGSKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMIRS  933


>gi|333919582|ref|YP_004493163.1| Aconitate hydratase 1 [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481803|gb|AEF40363.1| Aconitate hydratase 1 [Amycolicicoccus subflavus DQS3-9A1]
Length=934

 Score = 1530 bits (3961),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 743/940 (80%), Positives = 838/940 (90%), Gaps = 7/940 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            S S++SFGA  TL+VG+ SY+I+RL AVP T KLPY+LKVLAENLLR EDG NIT++HI 
Sbjct  2    STSIDSFGARGTLEVGDNSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGLNITEEHIN  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AI+ WDP A+PS+EIQ+TPARV+MQDFTGVPC+VDLATMREA+  LGG+PDKVNPL+PA+
Sbjct  62   AISKWDPSAQPSVEIQFTPARVIMQDFTGVPCVVDLATMREAVTTLGGDPDKVNPLSPAE  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FGR DAFERNVE+EYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  122  MVIDHSVILDIFGRPDAFERNVELEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VM R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLARTVMVRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEI PGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIHPGVTATDVVLTVTDMLRKHGVVGKFVEFYGQGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPIDEETI YLR TGR  +Q+ALVEAYAK QGMWHD   EPE+SEYLEL+LS
Sbjct  302  EFGSTAAIFPIDEETINYLRLTGRDEDQLALVEAYAKEQGMWHDADREPEYSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+++K+ FR+ I++YV     ++   PHS LDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRIPLSESKTAFRKDIHNYV----EENHATPHSHLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA+DD      ++SAA  ++GR S P++V S+E GEFVLDHGAV +A ITSCTNT
Sbjct  418  PAALSFADDDAGD---LNSAANGSEGRPSKPIKVVSEEHGEFVLDHGAVAVAGITSCTNT  474

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VM+GAALLARNAVEKGLTSKPWVKT +APGSQVV+DYY+++GLWPYLEKLGF+L G
Sbjct  475  SNPSVMIGAALLARNAVEKGLTSKPWVKTNMAPGSQVVSDYYEKAGLWPYLEKLGFHLGG  534

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLPEEISKA+N++DL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  535  YGCTTCIGNTGPLPEEISKAINEHDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  594

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
            ALAGTMDFDF+T  LG DK+G +V+L+DIWPS Q++ DTI +AI+QEMF ++YADVFKGD
Sbjct  595  ALAGTMDFDFETDSLGNDKEGNDVYLKDIWPSPQEIDDTIKSAISQEMFKKSYADVFKGD  654

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
            +RWRNLPTP GNTFEW  +STYVRK PYF+GMT +  PV ++ GARVLALLGDSVTTDHI
Sbjct  655  ERWRNLPTPEGNTFEWGEDSTYVRKAPYFDGMTLETTPVSDVKGARVLALLGDSVTTDHI  714

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IKPGTPAA+YLD HGV+RKDYNS GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  715  SPAGPIKPGTPAAQYLDAHGVERKDYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  774

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ GGPQAFIYDA+ NY    IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  775  YTRDFTQDGGPQAFIYDASMNYQKAGIPLVVIGGKEYGSGSSRDWAAKGTRLLGVKAVIT  834

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFPEG+SA +LG+DGTEVFDI GI+ LN+G TP T+ V AT
Sbjct  835  ESFERIHRSNLIGMGVVPLQFPEGESAKTLGIDGTEVFDIEGIEKLNEGVTPSTMKVTAT  894

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            K +G  IEFDAVVRIDTPGE DYYRNGGILQYVLRN++KS
Sbjct  895  KDNGEKIEFDAVVRIDTPGERDYYRNGGILQYVLRNMVKS  934


>gi|317508709|ref|ZP_07966364.1| aconitate hydratase 1 [Segniliparus rugosus ATCC BAA-974]
 gi|316253030|gb|EFV12445.1| aconitate hydratase 1 [Segniliparus rugosus ATCC BAA-974]
Length=934

 Score = 1529 bits (3960),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 742/939 (80%), Positives = 835/939 (89%), Gaps = 7/939 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSF + DTLKV ++ Y+I+RLD V    KLPYSLK+LAENLLR EDG+NIT+DH+ A+
Sbjct  3    SINSFNSRDTLKVDDQEYEIFRLDRVEGLEKLPYSLKILAENLLRTEDGANITQDHVNAL  62

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP AEPS+EIQ+TPARVVMQDFTGVPC+VDLATMREA+ +LGG+P+KVNPL+PA+LV
Sbjct  63   ANWDPSAEPSVEIQFTPARVVMQDFTGVPCVVDLATMREAVTELGGDPNKVNPLSPAELV  122

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FGRADAFERNVE+EY+RN ERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  123  IDHSVILDVFGRADAFERNVELEYERNAERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  182

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLA  V TR+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  183  YLARTVFTRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  242

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTG I+PGVTATDVVLT+TE+LR+HGVVGKFVEFYG GVAEVPLANRATLGNMSPEF
Sbjct  243  GFKLTGSIKPGVTATDVVLTITEILRKHGVVGKFVEFYGAGVAEVPLANRATLGNMSPEF  302

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPIDEETI YLR TGR   Q+ LVEAYAK QG+WHD  HEP FSEYLEL+LS V
Sbjct  303  GSTAAIFPIDEETIDYLRLTGRDEHQLKLVEAYAKEQGLWHDAAHEPAFSEYLELDLSTV  362

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSIAGPKRPQDRI L+++K  FR+ I++YV    P     PH+KLDE VEE+FPASDP 
Sbjct  363  VPSIAGPKRPQDRILLSESKVAFRKDIHNYVEEQQPT----PHTKLDEAVEESFPASDPA  418

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
            +L+FA+DD      V SAA  ++GR S PV VKSDE GEF+LDHGAVV+A ITSCTNTSN
Sbjct  419  KLSFADDDAVP---VFSAANGSEGRPSKPVLVKSDEHGEFILDHGAVVVAGITSCTNTSN  475

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLA+NAVEKGLTSKPWVKT +APGSQVV DYY+++GLWPYLEKLGFYL GYG
Sbjct  476  PSVMLGAALLAKNAVEKGLTSKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGFYLGGYG  535

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGN+GPLP+ ISKA+NDNDL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAYAL
Sbjct  536  CTTCIGNTGPLPDAISKAINDNDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYAL  595

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+ +PLG   DG+ V+L+DIWP+ +D+ DTI + IN+EMFT++YADVFKGD+R
Sbjct  596  AGTMDFDFEHEPLGTGTDGQPVYLKDIWPAPKDIEDTIKSTINREMFTKSYADVFKGDER  655

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WR++PTP G+TFEW  +STYVRK PYF+GM  +P PV +I GARVLALLGDSVTTDHISP
Sbjct  656  WRSIPTPEGDTFEWQDSSTYVRKAPYFDGMPLEPAPVADIKGARVLALLGDSVTTDHISP  715

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG+IKPGTPAA+YLD HGVDRKDYNS GSRRGNHEVM+RGTFANIRL+NQLLD VSGGYT
Sbjct  716  AGSIKPGTPAAQYLDAHGVDRKDYNSLGSRRGNHEVMVRGTFANIRLQNQLLDGVSGGYT  775

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQPGGPQAFIYDA+ NY    IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI ES
Sbjct  776  RDFTQPGGPQAFIYDASVNYQKAGIPLVVLGGKEYGSGSSRDWAAKGTTLLGVRAVITES  835

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP+G+SA SL L+GTEVFDI+GI+ LN+G TPKTV V ATK 
Sbjct  836  FERIHRSNLIGMGVIPLQFPKGESAYSLKLNGTEVFDISGIEKLNEGVTPKTVHVTATKE  895

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            DG+ +EFDAVVRIDTPGEADYYRNGGILQYVLRN++ +G
Sbjct  896  DGSKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMIAAG  934


>gi|312139641|ref|YP_004006977.1| aconitate hydratase [Rhodococcus equi 103S]
 gi|325676681|ref|ZP_08156355.1| aconitate hydratase [Rhodococcus equi ATCC 33707]
 gi|311888980|emb|CBH48293.1| aconitate hydratase [Rhodococcus equi 103S]
 gi|325552463|gb|EGD22151.1| aconitate hydratase [Rhodococcus equi ATCC 33707]
Length=933

 Score = 1527 bits (3954),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 748/939 (80%), Positives = 832/939 (89%), Gaps = 8/939 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + S+++FGA  TL+VG+ SY+I+RL AVP T KLPY+LKVLAENLLR EDG+NIT DHI 
Sbjct  2    TTSIDTFGAKGTLEVGDNSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDP AEPS+EIQ+TPARV+MQDFTGVPC+VDLATMREA+  LGG+P+KVNPL+PAD
Sbjct  62   AIANWDPSAEPSVEIQFTPARVIMQDFTGVPCVVDLATMREAVTTLGGDPNKVNPLSPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FGRADA ERNV++EYQRNGERYQFLRWGQGAFDDFKVVPPG GIVHQVN
Sbjct  122  MVIDHSVILDVFGRADALERNVDLEYQRNGERYQFLRWGQGAFDDFKVVPPGMGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VMTR+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLAPTVMTRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVT+MLR+HGVVGKFVEFYG GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTDMLRKHGVVGKFVEFYGAGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ETI YLR TGR+ EQ+ALVEAYAK QGMWHD   EP +SEYLEL+L 
Sbjct  302  EFGSTAAIFPIDGETINYLRLTGRSDEQLALVEAYAKEQGMWHDADKEPAYSEYLELDLG  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+ +K+ FR  I  YV NG   +    H+ LDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRILLSDSKAAFRRDIVTYVTNGDEAA----HTALDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+ A+D+V     V SAA  + GR S PV VK+D  GEFVLDHGAV +A ITSCTNT
Sbjct  418  PASLSTASDEVVA---VPSAANGSTGRPSKPVTVKTDR-GEFVLDHGAVAVAGITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL +KPWVKT +APGSQVV+DYY+++GLWPYLEKLGFYL G
Sbjct  474  SNPSVMLGAALLARNAVEKGLETKPWVKTNMAPGSQVVSDYYEKAGLWPYLEKLGFYLGG  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLPEEISKA+N++DLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  YGCTTCIGNTGPLPEEISKAINEHDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
            ALAGTMDFDF+T PLGQDKDG +VFL+DIWPS Q++ DTI +AI+Q+MF ++YADVFKGD
Sbjct  594  ALAGTMDFDFETDPLGQDKDGNDVFLKDIWPSAQEIDDTIKSAISQDMFRKSYADVFKGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
            +RW+NL TP+G+TF WD NSTYVRK PYF+GMT  P PV +ISGARVLALLGDSVTTDHI
Sbjct  654  ERWQNLATPAGDTFAWDENSTYVRKAPYFDGMTMDPAPVTDISGARVLALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IKPGTPAA+YLD +GV+RKDYNS GSRRGNHEVMIRGTFANIRL+NQLLD VSGG
Sbjct  714  SPAGPIKPGTPAAQYLDANGVERKDYNSLGSRRGNHEVMIRGTFANIRLQNQLLDGVSGG  773

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ G PQAFIYDA+QNY    IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  774  YTRDFTQEGAPQAFIYDASQNYQKAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGVKAVIT  833

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA+SLGLDGTEVFDI GI  LN+G TPKTV V AT
Sbjct  834  ESFERIHRSNLIGMGVVPLQFPAGESAASLGLDGTEVFDIAGITKLNEGVTPKTVKVTAT  893

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            K DG+ +EFDAVVRIDTPGEADYYRNGGILQYVLRN+++
Sbjct  894  KADGSKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMIR  932


>gi|3121732|sp|O08451.1|ACON_MYCAV RecName: Full=Aconitate hydratase; Short=Aconitase; AltName: 
Full=Citrate hydro-lyase
 gi|2183256|gb|AAC46192.1| aconitase [Mycobacterium avium]
Length=961

 Score = 1526 bits (3952),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 778/942 (83%), Positives = 831/942 (89%), Gaps = 10/942 (1%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + SVNSFGA + +KVG+KSYQIYRLDAVPNT KLPYSLKVLAENLLRNEDGSNITKDHIE
Sbjct  29   TDSVNSFGARNRVKVGDKSYQIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIE  88

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWDPKA  SIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNP+KVNPLAPAD
Sbjct  89   AIANWDPKAGASIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD  148

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            LVIDHSVIADLFG ADAFERNVEIEYQRNGERYQFLRW QGAF DFKVVPP   IVHQVN
Sbjct  149  LVIDHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWLQGAFSDFKVVPPRR-IVHQVN  207

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVM R GVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  208  IEYLARVVMERVGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  267

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGE      ATDVVLTVTE+  +HGVVGKFVEFYGEGVAEVPLANRATLGNMSP
Sbjct  268  VVGFKLTGEDPAPGAATDVVLTVTEICAKHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  327

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID+ETI YL+FTGR  EQVALVE YAK QG+WHDP HEP FSEYLEL+LS
Sbjct  328  EFGSTAAIFPIDQETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLS  387

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRIAL+QAKS FREQI  YVG+G        +SKLDEVV+ETFPASD
Sbjct  388  QVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGDG---QQGYSKLDEVVDETFPASD  444

Query  423  PGQLTFAN-DDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTN  481
            PG  +  + DD+     V SAAAHA+GR SNPV V+SDELGEFVLDHGAVVIAA+TSCTN
Sbjct  445  PGAPSNGHADDLPA---VQSAAAHANGRPSNPVTVRSDELGEFVLDHGAVVIAAVTSCTN  501

Query  482  TSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLV  541
            TSNPEVMLGAALLAR  VEKGL SKPWVKTT+APGSQVV+DYYD++GLWPYLEKLGFYLV
Sbjct  502  TSNPEVMLGAALLARQRVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLWPYLEKLGFYLV  561

Query  542  GYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIA  601
            GYGCTTCIGNSGPLPEEISKA+NDNDLSVTAVLSGNRNFEGRINPDVKMNY ASPPLV+A
Sbjct  562  GYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKMNYPASPPLVVA  621

Query  602  YALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG  661
            YALAGTM    + QPLG+DKDG +V+L+DI  SQ+ +        N E FT+NYADVFKG
Sbjct  622  YALAGTMT-RLEKQPLGKDKDGNDVYLKDICRSQKTLGHH-PIGDNSEWFTKNYADVFKG  679

Query  662  DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDH  721
            +  WRNLPTP+ NTFEW P+STYVRKPPYFEGM A+PEPV +IS ARV+ALLGDSVTTDH
Sbjct  680  EQAWRNLPTPTRNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISSARVVALLGDSVTTDH  739

Query  722  ISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSG  781
            ISPAG+IKPGTPAA+YLD+     +    FG RRGNHEVMIRGTFANIRLRN L DDV+G
Sbjct  740  ISPAGSIKPGTPAAQYLDDARRGPQGLQLFGCRRGNHEVMIRGTFANIRLRNLLHDDVAG  799

Query  782  GYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVI  841
            GYTRDFTQ GGPQAFIYDAAQNYAAQ+IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVI
Sbjct  800  GYTRDFTQDGGPQAFIYDAAQNYAAQNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVI  859

Query  842  AESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQA  901
            AESFERIHRSNLIGMGVIPLQFP+GKSA  LGLDGTEVFDITGI+ LN GKTPKTV V+A
Sbjct  860  AESFERIHRSNLIGMGVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKA  919

Query  902  TKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG  943
            +K      EFDAVVRIDTPGEADYYRNGGILQYVLRN+LKSG
Sbjct  920  SKNGSDAAEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG  961


>gi|169629814|ref|YP_001703463.1| aconitate hydratase ACN [Mycobacterium abscessus ATCC 19977]
 gi|169241781|emb|CAM62809.1| Probable aconitate hydratase ACN [Mycobacterium abscessus]
Length=962

 Score = 1526 bits (3950),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 742/938 (80%), Positives = 833/938 (89%), Gaps = 8/938 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            ++SVNSFGA  TL+VG++SY+I+RL+AVP T KLPYSLKVLAENLLR EDG+NITKDH+ 
Sbjct  31   TESVNSFGARGTLQVGDESYEIFRLNAVPGTEKLPYSLKVLAENLLRTEDGANITKDHVL  90

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            A+ANWDP AEPS+EIQ+TPARVVMQDFTGVPC+VDLATMREA+A LGG+PDKVNPL+PA+
Sbjct  91   ALANWDPSAEPSVEIQFTPARVVMQDFTGVPCVVDLATMREAVAALGGDPDKVNPLSPAE  150

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FG ADAFERNVE+EY+RN ERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  151  MVIDHSVILDVFGTADAFERNVELEYERNAERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  210

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VM R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  211  IEYLARTVMVRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  270

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  271  VVGFKLTGEIQPGVTATDVVLTVTDMLRKHGVVGKFVEFYGKGVAEVPLANRATLGNMSP  330

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID+ETI YLR TGR   Q+ALVEAYA+ QGMWHD  HEP FSEYLEL+LS
Sbjct  331  EFGSTAAIFPIDDETINYLRLTGRDEAQLALVEAYAREQGMWHDADHEPAFSEYLELDLS  390

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSI+GPKRPQDRI L+ AK+ FR+ I++YV    P     PH+ LDE VEE+FPASD
Sbjct  391  TVVPSISGPKRPQDRIELSDAKNAFRKDIHNYVEENHPA----PHTNLDEAVEESFPASD  446

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
               L+FA DD      + SAA   +GR S PV+V S E G FVLDHGAVV+A ITSCTNT
Sbjct  447  SAVLSFAEDDA----VIPSAANGGEGRPSKPVKVTSAERGNFVLDHGAVVVAGITSCTNT  502

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLA+ AVEKGLT+KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL G
Sbjct  503  SNPSVMLGAALLAKKAVEKGLTTKPWVKTNMAPGSQVVTDYYNKAGLWPYLEKLGYYLGG  562

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLP+EISKA+NDNDLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  563  YGCTTCIGNTGPLPDEISKAINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  622

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
             +AGTMDFDF+T PLG+D DG +VFL+DIWPS  ++ +TIA++IN+EMFT +YADVFKGD
Sbjct  623  GIAGTMDFDFETDPLGKDHDGNDVFLKDIWPSASEIEETIASSINREMFTSSYADVFKGD  682

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
            +RWR LPTP GNTF W  +STYVRK PYF+GM  +P PV +I GARVLALLGDSVTTDHI
Sbjct  683  ERWRGLPTPEGNTFAWSDDSTYVRKAPYFDGMPLEPTPVTDIKGARVLALLGDSVTTDHI  742

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG+IK GTPAA+YLDEHGV+RKDYNS GSRRGNHEVM+RGTFANIRLRNQLLDDVSGG
Sbjct  743  SPAGSIKSGTPAAQYLDEHGVERKDYNSLGSRRGNHEVMVRGTFANIRLRNQLLDDVSGG  802

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ GGPQ+FIYDA+ NY    IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  803  YTRDFTQDGGPQSFIYDASVNYQKAGIPLVVLGGKEYGSGSSRDWAAKGTRLLGVKAVIT  862

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA+SL LDGTE +DI+GI+ LN+G TPKTV V AT
Sbjct  863  ESFERIHRSNLIGMGVVPLQFPAGESAASLKLDGTETYDISGIEKLNEGSTPKTVQVTAT  922

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNIL  940
            + +G T++FDAVVRIDTPGEADYYRNGGILQYVLRN+L
Sbjct  923  RENGETVQFDAVVRIDTPGEADYYRNGGILQYVLRNML  960


>gi|111024157|ref|YP_707129.1| aconitate hydratase [Rhodococcus jostii RHA1]
 gi|110823687|gb|ABG98971.1| aconitate hydratase [Rhodococcus jostii RHA1]
Length=934

 Score = 1524 bits (3946),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 743/939 (80%), Positives = 835/939 (89%), Gaps = 7/939 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            S S++SFGA  TL+VGE SY+I+RL AVP T KLPY+LKVLAENLLR EDG+NIT DHI 
Sbjct  2    STSIDSFGAKGTLEVGENSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA+WDP A+P++EIQ+TPARV+MQDFTGVPCIVDLATMREA+  LGG+P+KVNPLAPA+
Sbjct  62   AIASWDPSADPNVEIQFTPARVIMQDFTGVPCIVDLATMREAVTALGGDPNKVNPLAPAE  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+ GRADAFERNVEIEY RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN
Sbjct  122  MVIDHSVIIDVAGRADAFERNVEIEYSRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IE+LA  +M R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEHLARTIMVRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEI+PGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIKPGVTATDVVLTVTDMLRKHGVVGKFVEFYGKGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ET+ YLR TGRT EQ+ALVEAYAK QG+WHD  HEPE+SEYLEL+L 
Sbjct  302  EFGSTAAIFPIDAETVSYLRLTGRTEEQLALVEAYAKEQGLWHDADHEPEYSEYLELDLG  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
            DVVPSIAGPKRPQDRI L+ +K+ FR+ I++YV    P      HS+LDE VEE+FPASD
Sbjct  362  DVVPSIAGPKRPQDRILLSDSKNAFRKDIHNYVEEHHPTG----HSQLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA DD A D  V SAA  A+GR + PV+V S++ GEF+LDHGAVVIA+ITSCTNT
Sbjct  418  PAALSFA-DDGAVD--VQSAANGAEGRPTKPVKVLSEDKGEFILDHGAVVIASITSCTNT  474

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL++KPWVKT++APGSQVV DYY++SGLWPYLEKLGFYLVG
Sbjct  475  SNPSVMLGAALLARNAVEKGLSAKPWVKTSMAPGSQVVTDYYNKSGLWPYLEKLGFYLVG  534

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGC TCIGNSGPL E+IS+A+ DNDL+ TAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  535  YGCATCIGNSGPLDEQISQAIQDNDLTATAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  594

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
            ALAGTMDFDF+   LGQD DG +VFL+DIWPS Q++ +TI ++I+QEM+ + YADVFKGD
Sbjct  595  ALAGTMDFDFEHDALGQDADGNDVFLKDIWPSPQEIQETINSSISQEMYVKGYADVFKGD  654

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
            +RWR LPTP G TFEWD NSTYVRKPPYF+GM  +P PV +I GARVLALLGDSVTTDHI
Sbjct  655  ERWRGLPTPEGKTFEWDANSTYVRKPPYFDGMPKEPTPVSDIKGARVLALLGDSVTTDHI  714

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IK GTPA++YLD +G+DRKDYNS+GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  715  SPAGNIKAGTPASQYLDANGIDRKDYNSYGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  774

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ GGPQAFIYDA+QNY    IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  775  YTRDFTQDGGPQAFIYDASQNYQKAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGVKAVIT  834

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA+SL LDGTEVFDI G++ LN+G TPKTV V AT
Sbjct  835  ESFERIHRSNLIGMGVVPLQFPAGESAASLKLDGTEVFDIEGVEKLNEGVTPKTVKVTAT  894

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            + +G  + FDAVVRIDTPGEADYYRNGGILQYVLRN++K
Sbjct  895  RENGEKVVFDAVVRIDTPGEADYYRNGGILQYVLRNMIK  933


>gi|54025453|ref|YP_119695.1| aconitate hydratase [Nocardia farcinica IFM 10152]
 gi|54016961|dbj|BAD58331.1| putative aconitate hydratase [Nocardia farcinica IFM 10152]
Length=933

 Score = 1519 bits (3932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 740/940 (79%), Positives = 835/940 (89%), Gaps = 8/940 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            + S+++FGA  TL+VG  SY+I+RL AVP T KLPY+LKVLAENLLR EDG+NIT DHI 
Sbjct  2    TTSIDTFGAKGTLEVGSNSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIANWD  AEP+ EIQ+TPARV+MQDFTGVPCIVDLATMREA+A LGG+PDKVNPLAPA+
Sbjct  62   AIANWDASAEPNTEIQFTPARVIMQDFTGVPCIVDLATMREAVATLGGDPDKVNPLAPAE  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FGR DAF+RNV+IEYQRNGERYQFLRWGQ AFDDFKVVPP TGIVHQVN
Sbjct  122  MVIDHSVIIDVFGREDAFQRNVDIEYQRNGERYQFLRWGQTAFDDFKVVPPSTGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IE+LA VVM R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEHLARVVMVRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVT+MLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTDMLRKHGVVGKFVEFYGKGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID+ T+ YLR TGR+ EQ+ALVEAYAK QG+WH+P  EPE+SEYLEL+LS
Sbjct  302  EFGSTAAIFPIDQVTVDYLRLTGRSDEQLALVEAYAKEQGLWHNPDFEPEYSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+++K  FR+ I++Y    + D+   PHSKLDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRILLSESKIAFRKDIHNY----TSDAEGAPHSKLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA+DD      + +AA +++GR + PV+V S+E G+FVLDHGAVV+A+ITSCTNT
Sbjct  418  PAVLSFADDDA----VLPTAANNSEGRPTKPVKVHSEEYGDFVLDHGAVVVASITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL  KPWVKT++APGSQVVN YY+++GLWPYL KLGF LV 
Sbjct  474  SNPSVMLGAALLARNAVEKGLARKPWVKTSMAPGSQVVNGYYEKAGLWPYLNKLGFNLVA  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            +GC TCIGN+GPLPEEIS+A+NDNDL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  FGCATCIGNTGPLPEEISQAINDNDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
            ALAGTMDFDF+T PLG+D +G +VFLRDIWPS +++ DTI A I+++MF  +Y DVFKGD
Sbjct  594  ALAGTMDFDFETDPLGKDTEGNDVFLRDIWPSPKEIQDTIDAVISRDMFLEDYKDVFKGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
            +RWR+LPTP G TF WD NSTYVRK PYF+GM  +P PV +I+GARVLALLGDSVTTDHI
Sbjct  654  ERWRSLPTPEGKTFAWDENSTYVRKAPYFDGMPQEPTPVTDITGARVLALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IKPGTPAA+YL+ +GV+RKDYNS+GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  714  SPAGNIKPGTPAAQYLEANGVERKDYNSYGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  773

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ GGPQAFIYDAAQNY A  IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  774  YTRDFTQEGGPQAFIYDAAQNYQAAGIPLVVLGGKEYGSGSSRDWAAKGTRLLGVKAVIT  833

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGVIPLQFP G+SA SLGLDGTEVFDI GI  LN+G TPKTV V AT
Sbjct  834  ESFERIHRSNLIGMGVIPLQFPAGESAKSLGLDGTEVFDIEGITKLNEGVTPKTVKVTAT  893

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            K DG  I FDAVVRIDTPGEADYYRNGGILQYVLRN++++
Sbjct  894  KADGEKITFDAVVRIDTPGEADYYRNGGILQYVLRNMIRA  933


>gi|302527156|ref|ZP_07279498.1| aconitate hydratase 1 [Streptomyces sp. AA4]
 gi|302436051|gb|EFL07867.1| aconitate hydratase 1 [Streptomyces sp. AA4]
Length=941

 Score = 1517 bits (3927),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/942 (79%), Positives = 832/942 (89%), Gaps = 7/942 (0%)

Query  1    VTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH  60
            VT+ S +SFGA DTL+V E SY+I+RLD V  +A+LPYSLK+L ENLLR EDG+NIT DH
Sbjct  7    VTAPSKDSFGAKDTLQVEENSYEIFRLDKVEGSARLPYSLKILLENLLRTEDGANITADH  66

Query  61   IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP  120
            I A+  WDP A+PS EIQ+TPARV+MQDFTGVPC+VDLATMREA+ DLGG+PDKVNPLAP
Sbjct  67   IRALGGWDPNADPSTEIQFTPARVIMQDFTGVPCVVDLATMREAVTDLGGDPDKVNPLAP  126

Query  121  ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ  180
            A++VIDHSVI D+FGRADAFERNVEIEY+RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQ
Sbjct  127  AEMVIDHSVIIDVFGRADAFERNVEIEYERNRERYQFLRWGQGAFDEFKVVPPGTGIVHQ  186

Query  181  VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  240
            VNIE+LA  VM R+G AYPD+CVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
Sbjct  187  VNIEHLARTVMARNGQAYPDSCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI  246

Query  241  PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM  300
            PRVVGF+LTGEI  GVTATDVVLT+TEMLR+HGVVGKFVEFYGE VA+VPLANRAT+GNM
Sbjct  247  PRVVGFKLTGEIPAGVTATDVVLTITEMLRRHGVVGKFVEFYGESVAQVPLANRATIGNM  306

Query  301  SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN  360
            SPEFGSTAAIFPIDEET++YL+ TGR+ EQVALVEAYAK QG+WHDP HE ++SEYLEL+
Sbjct  307  SPEFGSTAAIFPIDEETVRYLKLTGRSAEQVALVEAYAKEQGLWHDPSHEAQYSEYLELD  366

Query  361  LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA  420
            LS VVPSIAGPKRPQDRI L+ AKS+FR+ ++ YV    P     PH+ +DE VEE+FPA
Sbjct  367  LSTVVPSIAGPKRPQDRIELSDAKSSFRKSVHDYVEGEQPT----PHTNVDEKVEESFPA  422

Query  421  SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT  480
            SD   L+F ++   T   V SAA  A GR S PV+V S + GEFVLDHGAVVIA+ITSCT
Sbjct  423  SDAPALSFQDE---TAVPVQSAANGATGRPSKPVKVSSADRGEFVLDHGAVVIASITSCT  479

Query  481  NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL  540
            NTSNP VMLGAALLARNAV+KGL+ KPWVKT++APGSQVV DYY+++GLWPYLEKLG++L
Sbjct  480  NTSNPSVMLGAALLARNAVDKGLSVKPWVKTSMAPGSQVVTDYYEKAGLWPYLEKLGYHL  539

Query  541  VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI  600
            VGYGCTTCIGNSGPLPEE+S AV +NDL+V +VLSGNRNFEGRINPDVKMNYLASPPLVI
Sbjct  540  VGYGCTTCIGNSGPLPEEVSAAVQENDLTVVSVLSGNRNFEGRINPDVKMNYLASPPLVI  599

Query  601  AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK  660
            AYALAGTMDFDF+ QPLGQD +G +VFL+DIWPS Q++ +TI +AI QEMF+++YADVF 
Sbjct  600  AYALAGTMDFDFENQPLGQDSEGNDVFLKDIWPSPQEIQETIDSAITQEMFSKDYADVFD  659

Query  661  GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD  720
            G +RW++LPTP+G TF+WD  STYVRKPPYF+GMTA+P PV +ISGARVLA LGDSVTTD
Sbjct  660  GGERWKSLPTPTGKTFDWDAESTYVRKPPYFDGMTAEPAPVRDISGARVLAKLGDSVTTD  719

Query  721  HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS  780
            HISPAGAIK  TPA RYL EHG++RKD+NS+GSRRGNHEVMIRGTFANIRLRNQLLDDV 
Sbjct  720  HISPAGAIKADTPAGRYLTEHGIERKDFNSYGSRRGNHEVMIRGTFANIRLRNQLLDDVQ  779

Query  781  GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV  840
            GGYTRDFTQ GGPQAFIYDAAQNYAA   PLVV GGKEYGSGSSRDWAAKGT LLGVRAV
Sbjct  780  GGYTRDFTQEGGPQAFIYDAAQNYAAAGTPLVVLGGKEYGSGSSRDWAAKGTSLLGVRAV  839

Query  841  IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ  900
            I ESFERIHRSNLIGMGVIPLQFPEG+SASSL LDGTE FDI GI  LN+G+TP+TV V 
Sbjct  840  ITESFERIHRSNLIGMGVIPLQFPEGESASSLKLDGTETFDIEGITKLNEGETPRTVHVT  899

Query  901  ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            ATK DG+ +EFDAVVRIDTPGEADYYRNGGILQYVLR + +S
Sbjct  900  ATKEDGSKVEFDAVVRIDTPGEADYYRNGGILQYVLRKMTQS  941


>gi|326382232|ref|ZP_08203924.1| aconitate hydratase [Gordonia neofelifaecis NRRL B-59395]
 gi|326198962|gb|EGD56144.1| aconitate hydratase [Gordonia neofelifaecis NRRL B-59395]
Length=932

 Score = 1513 bits (3918),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 739/938 (79%), Positives = 826/938 (89%), Gaps = 7/938 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSF +  TL+VGE SY+I+RL AVP T KLPY+LKVLAENLLR EDG+NIT DHI A+
Sbjct  2    SINSFDSRGTLQVGENSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGANITTDHINAL  61

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP A+PSIEIQ+TPARV+MQDFTGVPC+VDLATMREAI  LGG+P+KVNPL+PA++V
Sbjct  62   ANWDPSADPSIEIQFTPARVLMQDFTGVPCVVDLATMREAITALGGDPNKVNPLSPAEMV  121

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FGRADAFERNVE+EY+RNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE
Sbjct  122  IDHSVILDVFGRADAFERNVELEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  181

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLA  +M RDG AYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  182  YLARSIMVRDGKAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  241

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI+PGVTATDVVLTVT+MLRQHGVVGKFVEFYG+GVAEVPLANRATLGNMSPEF
Sbjct  242  GFKLTGEIKPGVTATDVVLTVTDMLRQHGVVGKFVEFYGKGVAEVPLANRATLGNMSPEF  301

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GST AIFPID ETI YLR TGR  EQ+ALVEAYAK QGMWHDP+HEP +SEYLEL+L  V
Sbjct  302  GSTCAIFPIDAETINYLRLTGRDDEQLALVEAYAKEQGMWHDPEHEPAYSEYLELDLGTV  361

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSIAGPKRPQDRI L+++K  FR+ I++YV    P +    H++LDE VEE+FPASDP 
Sbjct  362  VPSIAGPKRPQDRILLSESKVAFRKDIHNYVEEQHPAA----HTQLDEAVEESFPASDPA  417

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             L+FA+D       V SAA  + GR S PV+V   E GEF+LDHGAV +A ITSCTNTSN
Sbjct  418  VLSFADDGAVN---VQSAANGSHGRPSKPVKVVDPERGEFILDHGAVAVAGITSCTNTSN  474

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VM+GA LLARNAVEKGL SKPWVKT +APGSQVV DYY+++GLWPYLEKLGFYL GYG
Sbjct  475  PSVMIGAGLLARNAVEKGLASKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGFYLGGYG  534

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGN+GPLP+EISKAVNDNDLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAYAL
Sbjct  535  CTTCIGNTGPLPDEISKAVNDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYAL  594

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+T+ LGQD DG +VFL+DIWPS Q++ DTI  AI+Q+MF ++YADVF GDDR
Sbjct  595  AGTMDFDFETEALGQDTDGNDVFLKDIWPSAQEIDDTIKTAISQDMFRKSYADVFAGDDR  654

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            W+ L TP G+TF WD  STYVRK PYF+GMT +P+PV +I GARVLALLGDSVTTDHISP
Sbjct  655  WQGLNTPEGDTFAWDDKSTYVRKAPYFDGMTLEPQPVSDIKGARVLALLGDSVTTDHISP  714

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AG IKPGTPAA+YLD +GV RKDYNS GSRRGNHEVMIRGTFANIRL+NQLLD VSGGYT
Sbjct  715  AGPIKPGTPAAQYLDANGVARKDYNSLGSRRGNHEVMIRGTFANIRLQNQLLDGVSGGYT  774

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQ GGPQ+FIYDA+ NY A  IPLVV GGKEYGSGSSRDWAAKGT+LLGV+AVI ES
Sbjct  775  RDFTQDGGPQSFIYDASVNYKAAGIPLVVLGGKEYGSGSSRDWAAKGTVLLGVKAVITES  834

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGV+PLQFP G++A +LGLDGTEVFDI GI  LN+G TPKT+ V ATK 
Sbjct  835  FERIHRSNLIGMGVVPLQFPAGENAKTLGLDGTEVFDIEGITALNEGVTPKTLKVTATKE  894

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            +G  +EFDAVVRIDTPGEADYYRNGGILQYVLRN+++S
Sbjct  895  NGDKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMIQS  932


>gi|324998571|ref|ZP_08119683.1| aconitate hydratase 1 [Pseudonocardia sp. P1]
Length=935

 Score = 1511 bits (3911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 720/938 (77%), Positives = 817/938 (88%), Gaps = 5/938 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S +SFGA   L VG   Y+I+RL AV  + +LP+SLKVL ENLLR EDG+N+T DHI A+
Sbjct  3    STDSFGARGQLDVGGTGYEIFRLSAVEGSQRLPFSLKVLLENLLRTEDGANVTADHINAL  62

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP+AEP  EIQ+TPARV+MQDFTGVPC+VDLATMREA+ ++GG+P KVNPLAPA+LV
Sbjct  63   ANWDPQAEPDTEIQFTPARVIMQDFTGVPCVVDLATMREAVTEMGGDPAKVNPLAPAELV  122

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSV+ D FG ADAFE+N+E EY RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQVNIE
Sbjct  123  IDHSVMIDFFGTADAFEKNIEFEYGRNKERYQFLRWGQGAFDEFKVVPPGTGIVHQVNIE  182

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
             LA VVM R+G AYPDT VGTDSHTTMVNG+GVLGWGVGGIEAEAAMLGQPVSMLIP+V+
Sbjct  183  NLARVVMPRNGQAYPDTLVGTDSHTTMVNGIGVLGWGVGGIEAEAAMLGQPVSMLIPKVL  242

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI  GVTATDVVLT+TEMLR+ GVVGKFVEFYG GV  VPLANRAT+GNMSPEF
Sbjct  243  GFKLTGEIPTGVTATDVVLTITEMLRREGVVGKFVEFYGAGVGAVPLANRATIGNMSPEF  302

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPID+ET++YL+ TGR+ EQ+ALVEAYAK QG+WHDP+HEP +S+ LEL+LS V
Sbjct  303  GSTAAIFPIDDETVRYLKLTGRSAEQIALVEAYAKEQGLWHDPEHEPVYSQTLELDLSTV  362

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
             PSIAGPKRPQDRI L++AK  FR+ ++ Y  +   ++     S +DE  +E+FPASD  
Sbjct  363  KPSIAGPKRPQDRIELSEAKPAFRKSVHDYTDD---EAAEGTLSGVDESSDESFPASDAP  419

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             L+FA+DD A    VHSAA   +GR S PV V S   GEFVLDHGAVVIA+ITSCTNTSN
Sbjct  420  ALSFADDDAA--PVVHSAANGGEGRPSKPVTVTSSSRGEFVLDHGAVVIASITSCTNTSN  477

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLA+NAV+KGLT+KPWVKT++APGSQVV DYY+++GLWPYL+KLG+ LVGYG
Sbjct  478  PSVMLGAALLAKNAVDKGLTTKPWVKTSMAPGSQVVTDYYEKAGLWPYLDKLGYNLVGYG  537

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPLPEEIS+AVNDNDL+V +VLSGNRNFEGRINPDVKMNYLASPPLVIAYAL
Sbjct  538  CTTCIGNSGPLPEEISQAVNDNDLTVVSVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  597

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+ QPLGQ  DG +VFLRDIWPS +D++  + +AI+ +MFT+NY+DVF+GD+R
Sbjct  598  AGTMDFDFEAQPLGQGSDGTDVFLRDIWPSSEDITSVVDSAIDSDMFTKNYSDVFRGDER  657

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WR LPTP G TFEWD  STYVRKPPYFEGM ++P PV +I+GARVLALLGDSVTTDHISP
Sbjct  658  WRALPTPEGQTFEWDQQSTYVRKPPYFEGMASEPSPVSDIAGARVLALLGDSVTTDHISP  717

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AGAIKPGTPAA+YLDE+G+++KDYNSFGSRRGNHEVMIRGTFANIRLRN LLDDVSGGYT
Sbjct  718  AGAIKPGTPAAQYLDENGIEKKDYNSFGSRRGNHEVMIRGTFANIRLRNLLLDDVSGGYT  777

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFTQ G PQAFIYDAAQNYAAQ  PLVV GGKEYGSGSSRDWAAKGT LLGV+AVI ES
Sbjct  778  RDFTQDGAPQAFIYDAAQNYAAQDTPLVVLGGKEYGSGSSRDWAAKGTALLGVKAVIVES  837

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFPEG+SA SLGLDGTE FD+ GI  LNDGKTPK+V V ATK 
Sbjct  838  FERIHRSNLIGMGVIPLQFPEGESARSLGLDGTETFDVAGITELNDGKTPKSVHVTATKT  897

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             G T+EFDA VRIDTPGEADYYRNGGILQYVLR +LKS
Sbjct  898  SGETVEFDAKVRIDTPGEADYYRNGGILQYVLRGMLKS  935


>gi|258652503|ref|YP_003201659.1| aconitate hydratase 1 [Nakamurella multipartita DSM 44233]
 gi|258555728|gb|ACV78670.1| aconitate hydratase 1 [Nakamurella multipartita DSM 44233]
Length=947

 Score = 1511 bits (3911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 727/942 (78%), Positives = 815/942 (87%), Gaps = 11/942 (1%)

Query  5    SVNSFGAHDTLKVGEKSYQIYR---LDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHI  61
            S +SF A DTL VG++SY IYR   LD + N  KLP+SLKVL ENL+R EDG+NIT DHI
Sbjct  5    SKDSFAAKDTLTVGDRSYDIYRILGLDGLENAGKLPFSLKVLLENLIRTEDGANITADHI  64

Query  62   EAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPA  121
             ++ANWDP A+P IEIQ+TPARV+MQDFTGVPC+VDLATMREA+ADLGG+PDK+NPLAPA
Sbjct  65   RSLANWDPSADPDIEIQFTPARVIMQDFTGVPCVVDLATMREAMADLGGDPDKINPLAPA  124

Query  122  DLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQV  181
            ++VIDHSVIAD+FGRADAFERNVE+EY+RN ERYQFLRWGQ AFD+FKVVPPGTGIVHQV
Sbjct  125  EMVIDHSVIADVFGRADAFERNVELEYERNRERYQFLRWGQTAFDEFKVVPPGTGIVHQV  184

Query  182  NIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP  241
            NIE+LA VVM R G+AYPD+CVGTDSHTTMVNG+GVLGWGVGGIEAEAAMLGQPVSMLIP
Sbjct  185  NIEHLARVVMYRGGIAYPDSCVGTDSHTTMVNGIGVLGWGVGGIEAEAAMLGQPVSMLIP  244

Query  242  RVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMS  301
            RVVGF+LTGEI  GVTATDVVLT+TEMLR+HGVVGKFVEFYG+GV +VPLANRAT+GNMS
Sbjct  245  RVVGFKLTGEIPTGVTATDVVLTITEMLRKHGVVGKFVEFYGDGVGQVPLANRATIGNMS  304

Query  302  PEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNL  361
            PEFGSTAA+FPID ET  YL  TGR  EQVALVEAYAKAQG+WHDP  EP +SEYLEL+L
Sbjct  305  PEFGSTAAMFPIDSETTDYLTLTGRPAEQVALVEAYAKAQGLWHDPAQEPVYSEYLELDL  364

Query  362  SDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPAS  421
            S VVPSIAGPKRPQDRIAL+ AK +FR+ ++ YV NG       P +KLDE +EE+FPAS
Sbjct  365  SSVVPSIAGPKRPQDRIALSDAKHSFRKAVHDYVVNGD----AAPETKLDEGIEESFPAS  420

Query  422  DPGQLT--FANDDVATD--ETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAIT  477
            DP  ++   A +D  TD    +HSAA  A GR S P +V + E G+F LDHGAVVIAAIT
Sbjct  421  DPASVSAVHAEEDANTDVVAALHSAALGASGRPSKPTKVSTSEYGDFELDHGAVVIAAIT  480

Query  478  SCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLG  537
            SCTNTSNP VMLGAALLARNAV+KGLT KPWVKTT+APGSQVV DYY+++GLWPYL KLG
Sbjct  481  SCTNTSNPSVMLGAALLARNAVDKGLTVKPWVKTTMAPGSQVVTDYYEKAGLWPYLNKLG  540

Query  538  FYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPP  597
            + LVGYGCTTCIGNSGPLP+EIS AVN+ DL+V +VLSGNRNFEGRINPDVKMNYLASPP
Sbjct  541  YNLVGYGCTTCIGNSGPLPDEISAAVNEADLTVVSVLSGNRNFEGRINPDVKMNYLASPP  600

Query  598  LVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYAD  657
            LVIAYALAGTMDFDF  QPLGQ  DG +++L+DIWP+ Q++  TI AAINQ+MFT +YAD
Sbjct  601  LVIAYALAGTMDFDFDEQPLGQSPDGSDIYLKDIWPTPQEIQATIGAAINQQMFTDSYAD  660

Query  658  VFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSV  717
            VF G +RW+ LPTP G TFEWDP STYVRKPPYF+GM A PEPV +ISGARVLA LGDSV
Sbjct  661  VFDGGERWKALPTPEGKTFEWDPESTYVRKPPYFDGMPATPEPVTDISGARVLAKLGDSV  720

Query  718  TTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLD  777
            TTDHISPAGAIK  TPA +YL EHG+ RKD+NS+GSRRGNHEVMIRGTFANIRLRNQLLD
Sbjct  721  TTDHISPAGAIKADTPAGKYLTEHGIVRKDFNSYGSRRGNHEVMIRGTFANIRLRNQLLD  780

Query  778  DVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGV  837
            DV GGYTRDFTQ GGPQAFIYDAAQNYAA  +PLVV GGKEYGSGSSRDWAAKGT LLGV
Sbjct  781  DVQGGYTRDFTQDGGPQAFIYDAAQNYAAAGVPLVVLGGKEYGSGSSRDWAAKGTALLGV  840

Query  838  RAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTV  897
            RAVI ESFERIHRSNLIGMGVIPLQFPEG++  +LGLDG E FDI+GI  LN G TP+TV
Sbjct  841  RAVITESFERIHRSNLIGMGVIPLQFPEGETVKTLGLDGDETFDISGITELNSGTTPRTV  900

Query  898  CVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNI  939
             V ATK  G  +EFDAVVRIDTPGEADYYRNGGI+QYVLR++
Sbjct  901  KVTATKPSGDVVEFDAVVRIDTPGEADYYRNGGIMQYVLRSL  942


>gi|257056245|ref|YP_003134077.1| aconitase [Saccharomonospora viridis DSM 43017]
 gi|256586117|gb|ACU97250.1| aconitase [Saccharomonospora viridis DSM 43017]
Length=942

 Score = 1509 bits (3906),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/936 (79%), Positives = 823/936 (88%), Gaps = 3/936 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S NSFGA DTL+VG+ SY+++RLD +  + +LPYSLK+L ENLLR EDG+NIT +HI A+
Sbjct  6    SKNSFGARDTLRVGDASYEVFRLDKIKGSERLPYSLKILLENLLRTEDGANITAEHINAL  65

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDPKAEPSIEIQ+TPARVVMQDFTGVPC+VDLATMREA+A+LGG+PDKVNPLAPA+LV
Sbjct  66   ANWDPKAEPSIEIQFTPARVVMQDFTGVPCVVDLATMREAVAELGGDPDKVNPLAPAELV  125

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FGRADAFERNVEIEY+RN ERYQFLRWGQ AF +FKVVPPGTGIVHQVNIE
Sbjct  126  IDHSVIIDVFGRADAFERNVEIEYERNRERYQFLRWGQNAFKEFKVVPPGTGIVHQVNIE  185

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            YLA  VM R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  186  YLARTVMARNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  245

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI PG TATDVVLT+TEMLR+HGVVGKFVEFYGEGV+ VPLANRAT+GNMSPEF
Sbjct  246  GFKLTGEIPPGATATDVVLTITEMLREHGVVGKFVEFYGEGVSAVPLANRATIGNMSPEF  305

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPIDEET++YL+ TGR+ EQ+ALVE YAK QG+WHDP    E+SEYLEL+LS V
Sbjct  306  GSTAAIFPIDEETLRYLKLTGRSEEQLALVETYAKEQGLWHDPSRTAEYSEYLELDLSTV  365

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD-P  423
            VPSIAGPKRPQDRI L+ AKS FR+ +  YV N   ++  +  S +DE  E++FPASD P
Sbjct  366  VPSIAGPKRPQDRINLSDAKSAFRKALPDYVSNDETEA--ETTSLVDEASEDSFPASDSP  423

Query  424  GQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTS  483
            G L     +    E  HSAA  A+GR S PV++ S + GEFVLDHGAVVIA+ITSCTNTS
Sbjct  424  GYLADGLREDRGGEPAHSAANGANGRPSKPVKITSPDRGEFVLDHGAVVIASITSCTNTS  483

Query  484  NPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGY  543
            NP VMLGAALLARNAVEKGL++KPWVKT++APGSQVV DYYD++GLWPYLEKLGF+LVGY
Sbjct  484  NPSVMLGAALLARNAVEKGLSTKPWVKTSMAPGSQVVTDYYDKAGLWPYLEKLGFHLVGY  543

Query  544  GCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  603
            GCTTCIGNSGPLPEEIS AV ++DLSV +VLSGNRNFEGRINPDVKMNYLASPPLVIAYA
Sbjct  544  GCTTCIGNSGPLPEEISAAVQEHDLSVVSVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  603

Query  604  LAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDD  663
            LAGTMDFDF+ QPLGQD  G +V+LRDIWPS Q++  TI  AI QEMF ++YA+VF G +
Sbjct  604  LAGTMDFDFENQPLGQDPQGNDVYLRDIWPSPQEIQQTIDTAITQEMFAKDYANVFDGGE  663

Query  664  RWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHIS  723
            RW++LPTP G TF WDP STYVRKPPYFEGMT +PEPV +I GARVLA LGDSVTTDHIS
Sbjct  664  RWKSLPTPEGKTFSWDPESTYVRKPPYFEGMTKEPEPVTDIHGARVLAKLGDSVTTDHIS  723

Query  724  PAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGY  783
            PAGAIK  +PA RYL EHGVDRKD+NS+GSRRGNHEVMIRGTFANIRLRNQLLD V GGY
Sbjct  724  PAGAIKADSPAGRYLLEHGVDRKDFNSYGSRRGNHEVMIRGTFANIRLRNQLLDGVQGGY  783

Query  784  TRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAE  843
            TRDFTQPGGPQ FIYDAAQNYAA++IPLVV GGKEYGSGSSRDWAAKGT LLGVRAVIAE
Sbjct  784  TRDFTQPGGPQTFIYDAAQNYAAKNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAE  843

Query  844  SFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK  903
            SFERIHRSNLIGMGVIPLQFPEG+SA SLGLDGTE +DI+GI  LN+G+TP+TV V ATK
Sbjct  844  SFERIHRSNLIGMGVIPLQFPEGESADSLGLDGTETYDISGITKLNEGETPRTVHVTATK  903

Query  904  GDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNI  939
             DG  +EFDAVVRIDTPGEADYYRNGGILQYVLR +
Sbjct  904  DDGTKVEFDAVVRIDTPGEADYYRNGGILQYVLRKM  939


>gi|296139783|ref|YP_003647026.1| aconitate hydratase 1 [Tsukamurella paurometabola DSM 20162]
 gi|296027917|gb|ADG78687.1| aconitate hydratase 1 [Tsukamurella paurometabola DSM 20162]
Length=938

 Score = 1506 bits (3898),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 740/945 (79%), Positives = 827/945 (88%), Gaps = 13/945 (1%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            SKS++SF +  TL+VG++SY+I+RL AVP T KLPY+LKVLAENLLR EDG+NIT DHI 
Sbjct  2    SKSIDSFSSRGTLEVGDQSYEIFRLSAVPGTEKLPYALKVLAENLLRTEDGANITTDHIN  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            A+ANWDP AEPS+EIQ+TPARV+MQDFTGVPCIVDLATMREA+  LGG+P+KVNPL+PAD
Sbjct  62   ALANWDPSAEPSVEIQFTPARVIMQDFTGVPCIVDLATMREAVTALGGDPNKVNPLSPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FGRADA ERNV++EYQRNGERYQFLRWGQGAFDDFKVVPPG GIVHQVN
Sbjct  122  MVIDHSVILDVFGRADALERNVDLEYQRNGERYQFLRWGQGAFDDFKVVPPGMGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA VVMTR+G AYPDTCVGTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLAPVVMTRNGQAYPDTCVGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEIQPGVTATDVVLTVT+MLRQHGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIQPGVTATDVVLTVTDMLRQHGVVGKFVEFYGKGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ETI YLR TGRT +Q+ALVEAYAK QGMWHDP+HEP +SEYLEL+LS
Sbjct  302  EFGSTAAIFPIDGETINYLRLTGRTDQQLALVEAYAKEQGMWHDPEHEPAYSEYLELDLS  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+++K  FR+ I++YV    P +    H++LDE VEE+FPASD
Sbjct  362  SVVPSIAGPKRPQDRILLSESKVAFRKDIHNYVEEQHPAT----HTQLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA+D       V SAA  A+GR S PV V + E G FVLDHGAV +A ITSCTNT
Sbjct  418  PAALSFADDGAV---NVQSAANGAEGRPSKPVTV-TGERGTFVLDHGAVAVAGITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGLT+KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL G
Sbjct  474  SNPSVMLGAALLARNAVEKGLTTKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGYYLGG  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLP+EISKA+NDNDL+VTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  YGCTTCIGNTGPLPDEISKAINDNDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
             LAGTMDFDF+T  LG+D DG +V+L+DIWPS Q++ DTI  AINQ+MF ++Y  VF GD
Sbjct  594  GLAGTMDFDFETDSLGKDHDGNDVYLKDIWPSAQEIDDTIKNAINQDMFRKSYETVFAGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
             RW+NL TP G+TF WD NSTYVRK PYF+GMT +PEPV +ISGARV+ALLGDSVTTDHI
Sbjct  654  HRWQNLDTPEGDTFAWDENSTYVRKAPYFDGMTMEPEPVSDISGARVMALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDV---  779
            SPAG IKPGTPAA+YLD HGV RKDYNS GSRRGNHEVMIRGTFANIRL+N++LD +   
Sbjct  714  SPAGPIKPGTPAAQYLDSHGVARKDYNSLGSRRGNHEVMIRGTFANIRLQNRVLDTIGLE  773

Query  780  --SGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGV  837
               GGYTRDFTQ GGPQ+FIYDA QNY A  IPLVV GGKEYGSGSSRDWAAKGT LLGV
Sbjct  774  GTQGGYTRDFTQEGGPQSFIYDACQNYQAAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGV  833

Query  838  RAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTV  897
            +AVI ESFERIHRSNLIGMGV+PLQFP+G+S  SLGLDGTE FDI GI  LN+G TPKTV
Sbjct  834  KAVIVESFERIHRSNLIGMGVVPLQFPKGESWKSLGLDGTETFDIAGITELNNGVTPKTV  893

Query  898  CVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             V ATK DG  +EFDA VRIDTPGEADYYRNGGILQYVLRN++ S
Sbjct  894  HVTATKTDGTKVEFDADVRIDTPGEADYYRNGGILQYVLRNMVNS  938


>gi|343927993|ref|ZP_08767459.1| aconitase [Gordonia alkanivorans NBRC 16433]
 gi|343762216|dbj|GAA14385.1| aconitase [Gordonia alkanivorans NBRC 16433]
Length=937

 Score = 1504 bits (3895),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 734/937 (79%), Positives = 823/937 (88%), Gaps = 8/937 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSFGA  TL VG+ SY+IYRL+AV    KLPY+LKVL ENLLR EDG+NITK+HIEA+
Sbjct  6    SINSFGARGTLDVGDNSYEIYRLNAVKGAEKLPYALKVLTENLLRTEDGANITKEHIEAL  65

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP AEPSIEIQ+TPARV+MQDFTGVPCIVDL TMR+A+ +LGG+PDKVNPLAPA++V
Sbjct  66   ANWDPSAEPSIEIQFTPARVIMQDFTGVPCIVDLTTMRDAVKELGGDPDKVNPLAPAEMV  125

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI + FG A AFERNVEIEYQRN ERY+FLRWGQGAFDDF+VVPPGTGIVHQVNIE
Sbjct  126  IDHSVIIEAFGNAQAFERNVEIEYQRNEERYKFLRWGQGAFDDFRVVPPGTGIVHQVNIE  185

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  +M RDGVAYPDTC+GTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  186  HLARSIMVRDGVAYPDTCIGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  245

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTG  +PGVTATDVVLT+TEMLR+HGVVGKFVEFYG GVAEVPLANRAT+GNMSPEF
Sbjct  246  GFKLTGSTKPGVTATDVVLTITEMLRKHGVVGKFVEFYGNGVAEVPLANRATIGNMSPEF  305

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDP-KHEPEFSEYLELNLSD  363
            GST A+FPIDEET+KYLR TGR+ E +ALVEAYAK QGMW +    E  +SEYLEL+L++
Sbjct  306  GSTCAMFPIDEETVKYLRLTGRSEETLALVEAYAKEQGMWLEKDAEEAVYSEYLELDLAE  365

Query  364  VVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDP  423
            VVPSIAGPKRPQDRI L  AK+ FR+ I++YV NG  +SP   H+KLDE VEETFPASDP
Sbjct  366  VVPSIAGPKRPQDRIELWDAKNAFRKDIHNYVENG--NSP--AHTKLDEAVEETFPASDP  421

Query  424  GQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTS  483
              LTFA+DD    E +HSAA  A+GR +NPVRV S+E G  +LDHG V IA+ITSCTNTS
Sbjct  422  ATLTFADDDA---EPLHSAANGAEGRPTNPVRVDSEERGSMILDHGIVTIASITSCTNTS  478

Query  484  NPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGY  543
            NP VMLGAALLA+ AVEKGLTSKPWVKT++APGSQVV  YY+++GLWPYLEKLGFYLVGY
Sbjct  479  NPSVMLGAALLAKKAVEKGLTSKPWVKTSMAPGSQVVTGYYEKAGLWPYLEKLGFYLVGY  538

Query  544  GCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  603
            GCTTCIGNSGPLPEEISKA+NDNDL+ TAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA
Sbjct  539  GCTTCIGNSGPLPEEISKAINDNDLTATAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  598

Query  604  LAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDD  663
            LAGTMDFDF+  PLG+D DG +VFL+DIWP+ +++  TIA++I+ E +  +YADVFKGD+
Sbjct  599  LAGTMDFDFENDPLGKDTDGNDVFLKDIWPTNEEIEATIASSISPEQYAADYADVFKGDE  658

Query  664  RWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHIS  723
            RW+NLPTPSG TFEWD  STYVRKPPYFEGM  +P PV +I GARVLA LGDSVTTDHIS
Sbjct  659  RWQNLPTPSGKTFEWDEKSTYVRKPPYFEGMQLEPSPVSDIKGARVLAKLGDSVTTDHIS  718

Query  724  PAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGY  783
            PA  IKPGTPAA+YLD +GV RKDYNS G+RRGNHEVMIR TF NIRL+NQLLD VSGGY
Sbjct  719  PASTIKPGTPAAQYLDANGVARKDYNSLGARRGNHEVMIRSTFGNIRLQNQLLDGVSGGY  778

Query  784  TRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAE  843
            TRDFTQ G PQ+FIYDAAQNYA Q+IPLVV GGKEYG+GSSRDWAAKGT LLGV+AVI E
Sbjct  779  TRDFTQEGAPQSFIYDAAQNYAEQNIPLVVLGGKEYGTGSSRDWAAKGTSLLGVKAVITE  838

Query  844  SFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK  903
            SFERIHRSNLIGMGVIPLQFPEG+S  SLGLDGTE FDI GI+ LN+GKTPKTV V ATK
Sbjct  839  SFERIHRSNLIGMGVIPLQFPEGESHKSLGLDGTETFDIAGIEELNEGKTPKTVHVTATK  898

Query  904  GDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNIL  940
             DG+ +EFDA VRIDTPGEADYYRNGGILQYVLRN++
Sbjct  899  EDGSKVEFDAKVRIDTPGEADYYRNGGILQYVLRNMI  935


>gi|229493658|ref|ZP_04387443.1| aconitate hydratase 1 [Rhodococcus erythropolis SK121]
 gi|229319619|gb|EEN85455.1| aconitate hydratase 1 [Rhodococcus erythropolis SK121]
Length=933

 Score = 1503 bits (3892),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/939 (79%), Positives = 825/939 (88%), Gaps = 8/939 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            S S++SFGA  TL+VGE SY+I+RL AVP T KLPYSLKVLAENLLR EDG+NIT DHI 
Sbjct  2    STSIDSFGAKGTLEVGENSYEIFRLSAVPGTEKLPYSLKVLAENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA+WDP AEPSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+  LGG+P+KVNPL+PAD
Sbjct  62   AIASWDPSAEPSIEIQFTPARVIMQDFTGVPCIVDLATMREAVTTLGGDPNKVNPLSPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FG+ADA ERNV++EY+RNGERYQFLRWGQGAFDDFKVVPPG GIVHQVN
Sbjct  122  MVIDHSVILDVFGQADALERNVDLEYERNGERYQFLRWGQGAFDDFKVVPPGMGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VM+R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLAPTVMSRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+L+GEI+PGVTATDVVLT TEMLR+HGVVGKFVEFYG GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLSGEIKPGVTATDVVLTATEMLRKHGVVGKFVEFYGNGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ETI+YLR TGR+ EQ+ALVEAYAK QG+WH+P  EP FSEY+EL+L 
Sbjct  302  EFGSTAAIFPIDAETIEYLRLTGRSDEQLALVEAYAKEQGLWHNPDKEPVFSEYIELDLG  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+++K+ FR+ I++YV    P      H++LDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRILLSESKTAFRKDIHNYVEENHPTE----HTQLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA DD A D  V SAA  A+GR S PV VKSD  GEFVLDHGAVV+A ITSCTNT
Sbjct  418  PAVLSFA-DDGAVD--VLSAANGAEGRPSKPVVVKSDA-GEFVLDHGAVVVAGITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL +KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL G
Sbjct  474  SNPSVMLGAALLARNAVEKGLATKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGYYLGG  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLPE +SKA+NDNDLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  YGCTTCIGNTGPLPEAVSKAINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
             LAGTMDFDF+T  LG D DG  V+L+DIWPS Q++ +TI ++I+Q+MF ++YA +F GD
Sbjct  594  GLAGTMDFDFETDSLGNDTDGNPVYLKDIWPSTQEIEETIKSSIDQDMFRKSYATIFAGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
             RW+NL TP G+TFEWD NSTYVRKPPYF+GMT  P PV +I GARVLALLGDSVTTDHI
Sbjct  654  SRWQNLETPKGDTFEWDVNSTYVRKPPYFDGMTMDPAPVKDIKGARVLALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IK GTPAA+YLD HGV+R DYNS GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  714  SPAGPIKVGTPAAQYLDSHGVERADYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  773

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ G PQAFIYDA+QNY A  IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  774  YTRDFTQEGAPQAFIYDASQNYQAAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGVKAVIT  833

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA SL LDGTE FDI G++ LN+G TPKT+ V AT
Sbjct  834  ESFERIHRSNLIGMGVVPLQFPVGESAGSLKLDGTETFDIEGVEKLNEGVTPKTMKVTAT  893

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            + +G  + FDAVVRIDTPGEADYYRNGGILQYVLRN+++
Sbjct  894  RENGEKVVFDAVVRIDTPGEADYYRNGGILQYVLRNMIR  932


>gi|226306555|ref|YP_002766515.1| aconitase [Rhodococcus erythropolis PR4]
 gi|226185672|dbj|BAH33776.1| aconitase [Rhodococcus erythropolis PR4]
Length=933

 Score = 1503 bits (3892),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/939 (79%), Positives = 825/939 (88%), Gaps = 8/939 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            S S++SFGA  TL+VGE SY+I+RL AVP T KLPYSLKVLAENLLR EDG+NIT DHI 
Sbjct  2    STSIDSFGAKGTLEVGENSYEIFRLSAVPGTEKLPYSLKVLAENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA+WDP AEPSIEIQ+TPARV+MQDFTGVPCIVDLATMREA+  LGG+P+KVNPL+PAD
Sbjct  62   AIASWDPSAEPSIEIQFTPARVIMQDFTGVPCIVDLATMREAVTTLGGDPNKVNPLSPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FG+ADA ERNV++EY+RNGERYQFLRWGQGAFDDFKVVPPG GIVHQVN
Sbjct  122  MVIDHSVILDVFGQADALERNVDLEYERNGERYQFLRWGQGAFDDFKVVPPGMGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VM+R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLAPTVMSRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+L+GEI+PGVTATDVVLT TEMLR+HGVVGKFVEFYG GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLSGEIKPGVTATDVVLTATEMLRKHGVVGKFVEFYGNGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ETI+YLR TGR+ EQ+ALVEAYAK QG+WH+P  EP FSEY+EL+L 
Sbjct  302  EFGSTAAIFPIDAETIEYLRLTGRSDEQLALVEAYAKEQGLWHNPDKEPVFSEYIELDLG  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+++K+ FR+ I++YV    P      H++LDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRILLSESKTAFRKDIHNYVEENYPTE----HTQLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA DD A D  V SAA  A+GR S PV VKSD  GEFVLDHGAVV+A ITSCTNT
Sbjct  418  PAVLSFA-DDGAVD--VLSAANGAEGRPSKPVVVKSDA-GEFVLDHGAVVVAGITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL +KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL G
Sbjct  474  SNPSVMLGAALLARNAVEKGLATKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGYYLGG  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLPE +SKA+NDNDLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  YGCTTCIGNTGPLPEAVSKAINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
             LAGTMDFDF+T  LG D DG  V+L+DIWPS Q++ +TI ++I+Q+MF ++YA +F GD
Sbjct  594  GLAGTMDFDFETDSLGNDTDGNPVYLKDIWPSTQEIEETIKSSIDQDMFRKSYATIFAGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
             RW+NL TP G+TFEWD NSTYVRKPPYF+GMT  P PV +I GARVLALLGDSVTTDHI
Sbjct  654  SRWQNLETPKGDTFEWDVNSTYVRKPPYFDGMTMDPAPVKDIKGARVLALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IK GTPAA+YLD HGV+R DYNS GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  714  SPAGPIKVGTPAAQYLDSHGVERADYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  773

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ G PQAFIYDA+QNY A  IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  774  YTRDFTQEGAPQAFIYDASQNYQAAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGVKAVIT  833

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA SL LDGTE FDI G++ LN+G TPKT+ V AT
Sbjct  834  ESFERIHRSNLIGMGVVPLQFPVGESAGSLKLDGTETFDIEGVEKLNEGVTPKTMKVTAT  893

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            + +G  + FDAVVRIDTPGEADYYRNGGILQYVLRN+++
Sbjct  894  RENGEKVVFDAVVRIDTPGEADYYRNGGILQYVLRNMIR  932


>gi|226366404|ref|YP_002784187.1| aconitate hydratase [Rhodococcus opacus B4]
 gi|226244894|dbj|BAH55242.1| aconitase [Rhodococcus opacus B4]
Length=933

 Score = 1502 bits (3889),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/939 (79%), Positives = 823/939 (88%), Gaps = 8/939 (0%)

Query  3    SKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIE  62
            S S++SFGA  TL+VGEKSY+++RL AVP T KLPYSLKVL ENLLR EDG+NIT DHI 
Sbjct  2    STSIDSFGAKGTLEVGEKSYEVFRLSAVPGTEKLPYSLKVLTENLLRTEDGANITADHIR  61

Query  63   AIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD  122
            AIA WDP A+PSIEIQ+TPARV+MQDFTGVPC+VDLATMREA+  LGG+P+KVNPL+PAD
Sbjct  62   AIAGWDPSAQPSIEIQFTPARVIMQDFTGVPCVVDLATMREAVTTLGGDPNKVNPLSPAD  121

Query  123  LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVN  182
            +VIDHSVI D+FG+ADA ERNV++EY+RNGERYQFLRWGQGAFDDFKVVPPG GIVHQVN
Sbjct  122  MVIDHSVILDIFGQADALERNVDLEYERNGERYQFLRWGQGAFDDFKVVPPGMGIVHQVN  181

Query  183  IEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  242
            IEYLA  VM R+G AYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR
Sbjct  182  IEYLAPTVMARNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPR  241

Query  243  VVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSP  302
            VVGF+LTGEI+PGVTATDVVLT TEMLR+HGVVGKFVEFYG+GVAEVPLANRATLGNMSP
Sbjct  242  VVGFKLTGEIKPGVTATDVVLTATEMLRKHGVVGKFVEFYGKGVAEVPLANRATLGNMSP  301

Query  303  EFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLS  362
            EFGSTAAIFPID ETI YLR TGR+ EQ+ALVEAYAK QG+WHDP +EP FSEY+EL+L 
Sbjct  302  EFGSTAAIFPIDSETIDYLRLTGRSDEQLALVEAYAKDQGLWHDPDNEPVFSEYIELDLG  361

Query  363  DVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASD  422
             VVPSIAGPKRPQDRI L+ +K+ FR+ I++YV    P      H++LDE VEE+FPASD
Sbjct  362  TVVPSIAGPKRPQDRILLSDSKTAFRKDIHNYVEENHPAE----HTQLDEAVEESFPASD  417

Query  423  PGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNT  482
            P  L+FA DD A D  V SAA  A+GR S PV VKSD  GEFVLDHGAVV+A ITSCTNT
Sbjct  418  PAVLSFA-DDGAVD--VLSAANGAEGRPSKPVVVKSDA-GEFVLDHGAVVVAGITSCTNT  473

Query  483  SNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVG  542
            SNP VMLGAALLARNAVEKGL +KPWVKT +APGSQVV DYY+++GLWPYLEKLG+YL G
Sbjct  474  SNPSVMLGAALLARNAVEKGLATKPWVKTNMAPGSQVVTDYYEKAGLWPYLEKLGYYLGG  533

Query  543  YGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAY  602
            YGCTTCIGN+GPLPE +SKA+NDNDLSVTAVLSGNRNFEGRI+PDVKMNYLASPPLVIAY
Sbjct  534  YGCTTCIGNTGPLPEAVSKAINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAY  593

Query  603  ALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGD  662
             LAGTMDFDF+T  LG D DG  V+L+DIWPS Q++ +TI  AI+Q+MF ++YA +F GD
Sbjct  594  GLAGTMDFDFETDSLGDDTDGNPVYLKDIWPSTQEIEETIKTAISQDMFRKSYATIFAGD  653

Query  663  DRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHI  722
             RW+NL TP G+TFEWD NSTYVRK PYF+GM   P PV +I GARVLALLGDSVTTDHI
Sbjct  654  SRWQNLSTPEGDTFEWDDNSTYVRKAPYFDGMPKDPAPVKDIKGARVLALLGDSVTTDHI  713

Query  723  SPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  782
            SPAG IK GTPAA+YLD HGV+RKDYNS GSRRGNHEVMIRGTFANIRLRNQLLDDVSGG
Sbjct  714  SPAGPIKVGTPAAQYLDSHGVERKDYNSLGSRRGNHEVMIRGTFANIRLRNQLLDDVSGG  773

Query  783  YTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIA  842
            YTRDFTQ GGPQAFIYDA+QNY A  IPLVV GGKEYGSGSSRDWAAKGT LLGV+AVI 
Sbjct  774  YTRDFTQDGGPQAFIYDASQNYQAAGIPLVVLGGKEYGSGSSRDWAAKGTSLLGVKAVIT  833

Query  843  ESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQAT  902
            ESFERIHRSNLIGMGV+PLQFP G+SA+SL LDGTE FDI G++ LN+G TPKT+ V AT
Sbjct  834  ESFERIHRSNLIGMGVVPLQFPAGESAASLKLDGTETFDIEGVEKLNEGVTPKTMKVTAT  893

Query  903  KGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            + +G  + FDAVVRIDTPGEADYYRNGGILQYVLRN++K
Sbjct  894  RENGEKVVFDAVVRIDTPGEADYYRNGGILQYVLRNMIK  932


>gi|300786832|ref|YP_003767123.1| aconitate hydratase 1 [Amycolatopsis mediterranei U32]
 gi|299796346|gb|ADJ46721.1| aconitate hydratase 1 [Amycolatopsis mediterranei U32]
 gi|340528318|gb|AEK43523.1| aconitate hydratase 1 [Amycolatopsis mediterranei S699]
Length=937

 Score = 1489 bits (3855),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 727/937 (78%), Positives = 815/937 (87%), Gaps = 6/937 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S +SFGA DTLKVG+ SY+++RL+ V    +LPYSLK+L ENLLR EDG+NIT DHI A+
Sbjct  6    SKDSFGAKDTLKVGDASYEVFRLNKVEGAERLPYSLKILLENLLRTEDGANITADHIRAL  65

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
             +WDP A+PSIEIQ+TPARV+MQDFTGVPC+VDLATMREA+ DLGG+PDKVNPLAPA+LV
Sbjct  66   GSWDPNADPSIEIQFTPARVIMQDFTGVPCVVDLATMREAVTDLGGDPDKVNPLAPAELV  125

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FGR DAFERNVEIEY+RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQVNIE
Sbjct  126  IDHSVIIDVFGRPDAFERNVEIEYERNRERYQFLRWGQGAFDEFKVVPPGTGIVHQVNIE  185

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  VM+R+G AYPD+CVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  186  HLARTVMSRNGQAYPDSCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  245

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI  GVTATDVVLT+TEMLR+HGVVGKFVEFYGE VAEVPLANRAT+GNMSPEF
Sbjct  246  GFKLTGEIPAGVTATDVVLTITEMLRRHGVVGKFVEFYGESVAEVPLANRATIGNMSPEF  305

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPIDEET++YL+ TGR+ EQVALVEAYAK QG+WHD   E  +SEYLEL+LS V
Sbjct  306  GSTAAIFPIDEETVRYLKLTGRSAEQVALVEAYAKEQGLWHDASREAAYSEYLELDLSTV  365

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSIAGPKRPQDRI L  AKS+FR+ I+ YV +G   +PH   +K+DE  EE+FPASD  
Sbjct  366  VPSIAGPKRPQDRIELTDAKSSFRKSIHDYV-DGEDATPH---TKMDEASEESFPASDAP  421

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
             L+FA DD A      SAA  A GR + PV+V + + GEFVLDHGAVVIA+ITSCTNTSN
Sbjct  422  SLSFAEDDAA--PVTSSAANGASGRPTKPVKVSTPDRGEFVLDHGAVVIASITSCTNTSN  479

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLARNAV+KGL  KPWVKT++APGSQVV DYY ++ LWPYLEKLG++LVGYG
Sbjct  480  PSVMLGAALLARNAVDKGLAVKPWVKTSMAPGSQVVTDYYTKANLWPYLEKLGYHLVGYG  539

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPL +EIS A+ +NDL+  +VLSGNRNFEGRINPDVKMNYLASPPLVIAYAL
Sbjct  540  CTTCIGNSGPLSDEISAAIQENDLTAVSVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  599

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF  QPLGQD  G +VFL+DIWP+ +++ +TI  AI QEMFT++YADVF G +R
Sbjct  600  AGTMDFDFANQPLGQDTQGNDVFLKDIWPTAKEIQETIDHAITQEMFTKDYADVFDGGER  659

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            W++LPTP G TFEWD  STYVRKPPYFEGMT +P PV +I+GARVLA LGDSVTTDHISP
Sbjct  660  WKSLPTPEGKTFEWDLESTYVRKPPYFEGMTPEPAPVTDITGARVLAKLGDSVTTDHISP  719

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYT  784
            AGAIKPGTPAA+YL EHGV++KD+NS+GSRRGNHEVMIRGTFANIRLRNQLLDDV GGYT
Sbjct  720  AGAIKPGTPAAQYLTEHGVEKKDFNSYGSRRGNHEVMIRGTFANIRLRNQLLDDVQGGYT  779

Query  785  RDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAES  844
            RDFT  G PQAFIYDAAQNYAA   PLVV GGKEYGSGSSRDWAAKGT LLGVRAVI ES
Sbjct  780  RDFTVEGAPQAFIYDAAQNYAAAGTPLVVLGGKEYGSGSSRDWAAKGTSLLGVRAVITES  839

Query  845  FERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKG  904
            FERIHRSNLIGMGVIPLQFP G+SASSLGLDGTE FDI GI  LNDG TP+TV V ATK 
Sbjct  840  FERIHRSNLIGMGVIPLQFPAGESASSLGLDGTETFDIAGITALNDGDTPRTVHVTATKA  899

Query  905  DGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILK  941
            DG  +EF+A VRIDTPGEADYYRNGGILQYVLR + +
Sbjct  900  DGTKVEFEADVRIDTPGEADYYRNGGILQYVLRKMTQ  936


>gi|262202328|ref|YP_003273536.1| aconitate hydratase 1 [Gordonia bronchialis DSM 43247]
 gi|262085675|gb|ACY21643.1| aconitate hydratase 1 [Gordonia bronchialis DSM 43247]
Length=938

 Score = 1477 bits (3824),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 724/946 (77%), Positives = 823/946 (87%), Gaps = 17/946 (1%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S+NSFGA  TL+VG+ SY+IYRL AV  T KLPY+LKVLAENLLR EDG+NITK+HIEAI
Sbjct  2    SINSFGARGTLEVGDNSYEIYRLSAVEGTEKLPYALKVLAENLLRTEDGANITKEHIEAI  61

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            ANWDP AEPS+EIQ+TPARV+MQDFTGVPC+VDLATMR+A+ +LGG+PDKVNPLAPA++V
Sbjct  62   ANWDPNAEPSVEIQFTPARVIMQDFTGVPCVVDLATMRDAVKELGGDPDKVNPLAPAEMV  121

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI + FG A AFERNVEIEYQRN ERY+FLRWGQGAFDDF+VVPPGTGIVHQVNIE
Sbjct  122  IDHSVIIEAFGNAQAFERNVEIEYQRNEERYKFLRWGQGAFDDFRVVPPGTGIVHQVNIE  181

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  VM RDGVAYPDTC+GTDSHTTM NGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  182  HLARSVMVRDGVAYPDTCIGTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  241

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTG  +PGVTATDVVLT+T+MLR+HGVVGKFVEFYG GVAEVPLANRAT+GNMSPEF
Sbjct  242  GFKLTGAAKPGVTATDVVLTITDMLRKHGVVGKFVEFYGNGVAEVPLANRATIGNMSPEF  301

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDP-KHEPEFSEYLELNLSD  363
            GST AIFPID ETI YL  TGR+ E + LVEAYAK QGMW +    EP++SEYLEL+L+D
Sbjct  302  GSTCAIFPIDGETINYLELTGRSKETLELVEAYAKEQGMWLEKDAEEPQYSEYLELDLAD  361

Query  364  VVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDP  423
            VVPSIAGPKRPQDRI L  AK+ FR+ I++YV  G  ++P    + +DE  EE+FPASD 
Sbjct  362  VVPSIAGPKRPQDRIELWDAKNAFRKDIHNYVEEG--NTPK--LNGVDEANEESFPASDA  417

Query  424  -------GQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAI  476
                    +L+F++D     E  H+AA  ++GR SNPV+V+S E G  +LDHG V IA+I
Sbjct  418  PATSPDAAKLSFSDD-----EPAHNAAKGSEGRPSNPVKVESAERGTMILDHGIVTIASI  472

Query  477  TSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKL  536
            TSCTNTSNP VMLGA LLA+ AVEKGLTSKPWVKT++APGSQVV  YYD++GLWPYLEKL
Sbjct  473  TSCTNTSNPSVMLGAGLLAKKAVEKGLTSKPWVKTSMAPGSQVVTGYYDKAGLWPYLEKL  532

Query  537  GFYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASP  596
            GF+LVGYGCTTCIGNSGPLPEEISKA+NDNDL+ TAVLSGNRNFEGRINPDVKMNYLASP
Sbjct  533  GFFLVGYGCTTCIGNSGPLPEEISKAINDNDLTATAVLSGNRNFEGRINPDVKMNYLASP  592

Query  597  PLVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYA  656
            PLVIAYALAGTMDFDF++ PLGQD+DG +VFL+DIWP+ +++S+TIA++I+ E +  +YA
Sbjct  593  PLVIAYALAGTMDFDFESDPLGQDQDGNDVFLKDIWPTNEEISETIASSISAEQYAADYA  652

Query  657  DVFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDS  716
            DVFKGD+RW+NLPTP G TFEWD  STYVRKPPYFEGM  +P+PV +I GARVLA LGDS
Sbjct  653  DVFKGDERWQNLPTPDGKTFEWDDESTYVRKPPYFEGMKPQPDPVSDIKGARVLAKLGDS  712

Query  717  VTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLL  776
            VTTDHISPA  IKPGTPAA+YLD HGV RKDYNS G+RRGNHEVMIR TF NIRL+NQLL
Sbjct  713  VTTDHISPASTIKPGTPAAQYLDAHGVARKDYNSLGARRGNHEVMIRSTFGNIRLQNQLL  772

Query  777  DDVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLG  836
            D VSGGYTRDFTQ G PQ+FIYDAAQNYA + IPLVV GGKEYG+GSSRDWAAKGT LLG
Sbjct  773  DGVSGGYTRDFTQDGAPQSFIYDAAQNYAEKGIPLVVLGGKEYGTGSSRDWAAKGTTLLG  832

Query  837  VRAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKT  896
            V+AVI ESFERIHRSNLIGMGVIPLQFP+G+S  SLGLDGTEVFDI+GI+ LN+G+TP T
Sbjct  833  VKAVITESFERIHRSNLIGMGVIPLQFPDGESHKSLGLDGTEVFDISGIEKLNEGETPAT  892

Query  897  VCVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
            V V ATK DG+TIEFDA VRIDTPGEADYYRNGGILQYVLRN++ S
Sbjct  893  VHVTATKEDGSTIEFDAKVRIDTPGEADYYRNGGILQYVLRNMINS  938


>gi|134100346|ref|YP_001106007.1| aconitate hydratase [Saccharopolyspora erythraea NRRL 2338]
 gi|133912969|emb|CAM03082.1| aconitate hydratase [Saccharopolyspora erythraea NRRL 2338]
Length=937

 Score = 1476 bits (3822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 725/939 (78%), Positives = 813/939 (87%), Gaps = 8/939 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S +SFGA  TLKVG+ SY+++RL+AV    +LPYSLK+L ENLLR EDG+NIT +H+ A+
Sbjct  6    SKDSFGARGTLKVGDASYEVFRLNAVDGAQRLPYSLKILLENLLRTEDGANITAEHVRAL  65

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            A WD KAEPS EIQ+TPARV+MQDFTGVPC+VDLATMREA+ADLGG+  KVNPLAPA+LV
Sbjct  66   AGWDAKAEPSTEIQFTPARVIMQDFTGVPCVVDLATMREAVADLGGDTSKVNPLAPAELV  125

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FG+ DAFERNVE EY RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQVNIE
Sbjct  126  IDHSVIIDVFGKPDAFERNVEFEYGRNKERYQFLRWGQGAFDEFKVVPPGTGIVHQVNIE  185

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  VM R+G AYPD+CVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  186  HLARTVMARNGQAYPDSCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  245

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI  G TATDVVLT+TEMLR+HGVVGKFVEFYG GVA VPLANRAT+GNMSPEF
Sbjct  246  GFKLTGEIPAGATATDVVLTITEMLRKHGVVGKFVEFYGSGVASVPLANRATIGNMSPEF  305

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GST AIFPID+ETI+YL+ TGR   QV LVEAYAK QG+WHDP  EP++SEYLEL+LS V
Sbjct  306  GSTCAIFPIDDETIRYLKLTGRDQAQVDLVEAYAKEQGLWHDPSVEPDYSEYLELDLSTV  365

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVG-NGSPDSPHDPHSKLDEVVEETFPASDP  423
            VPSIAGPKRPQDRI ++ AK +FR+ +  YV   G+ D      + LDE  +E+FPASD 
Sbjct  366  VPSIAGPKRPQDRIEVSAAKPSFRKSLTDYVQVTGTADD-----AALDEAGKESFPASDA  420

Query  424  GQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTS  483
              +T   +       VHSAA  ++GR SNP+ VKS+E GEF LDHGAVVIA+ITSCTNTS
Sbjct  421  PSVTHHGE--GDKPVVHSAANGSNGRPSNPILVKSEEYGEFELDHGAVVIASITSCTNTS  478

Query  484  NPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGY  543
            NP VMLGAALLARNAV+KGLT KPWVKT++APGSQVV DYY+++GLWPYLEKLGF+LVGY
Sbjct  479  NPSVMLGAALLARNAVDKGLTRKPWVKTSMAPGSQVVTDYYEKAGLWPYLEKLGFHLVGY  538

Query  544  GCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  603
            GCTTCIGNSGPLPEEIS AV +NDLSVT+VLSGNRNFEGRINPDVKMNYLASPPLVIAYA
Sbjct  539  GCTTCIGNSGPLPEEISAAVQENDLSVTSVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  598

Query  604  LAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDD  663
            LAGTMDFDF   PLG D +G  VFLRDIWPS Q+V  TI +AI QEMFT++Y+DVFKGD+
Sbjct  599  LAGTMDFDFSNDPLGDDTEGNPVFLRDIWPSPQEVQQTIDSAITQEMFTKDYSDVFKGDE  658

Query  664  RWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHIS  723
            RWR+LPTP G TF+WD +STYVRKPPYFEGM  +P PV  I+GARVLALLGDSVTTDHIS
Sbjct  659  RWRSLPTPEGETFDWDADSTYVRKPPYFEGMGMEPAPVEEITGARVLALLGDSVTTDHIS  718

Query  724  PAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGY  783
            PAGAIKP +PA +YL EHG++RKD+NS+GSRRGNHEVMIRGTFANIRLRN LLDDV GGY
Sbjct  719  PAGAIKPDSPAGKYLSEHGIERKDFNSYGSRRGNHEVMIRGTFANIRLRNLLLDDVQGGY  778

Query  784  TRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAE  843
            TRDFTQ GGPQ+FIYDAAQNYAAQ  PLVV GGKEYGSGSSRDWAAKGT LLGVRAVIAE
Sbjct  779  TRDFTQEGGPQSFIYDAAQNYAAQGTPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAE  838

Query  844  SFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK  903
            SFERIHRSNLIGMGVIPLQFPEG SA SLGLDGTE +D +GI  LNDG+TP+TV V A K
Sbjct  839  SFERIHRSNLIGMGVIPLQFPEGSSAKSLGLDGTETYDFSGITKLNDGETPETVKVTARK  898

Query  904  GDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             DG+T+EFDA VRIDTPGEADYYRNGGILQYVLR +++S
Sbjct  899  ADGSTVEFDAKVRIDTPGEADYYRNGGILQYVLRKMIRS  937


>gi|291007683|ref|ZP_06565656.1| aconitate hydratase [Saccharopolyspora erythraea NRRL 2338]
Length=941

 Score = 1476 bits (3821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 725/939 (78%), Positives = 813/939 (87%), Gaps = 8/939 (0%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S +SFGA  TLKVG+ SY+++RL+AV    +LPYSLK+L ENLLR EDG+NIT +H+ A+
Sbjct  10   SKDSFGARGTLKVGDASYEVFRLNAVDGAQRLPYSLKILLENLLRTEDGANITAEHVRAL  69

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            A WD KAEPS EIQ+TPARV+MQDFTGVPC+VDLATMREA+ADLGG+  KVNPLAPA+LV
Sbjct  70   AGWDAKAEPSTEIQFTPARVIMQDFTGVPCVVDLATMREAVADLGGDTSKVNPLAPAELV  129

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSVI D+FG+ DAFERNVE EY RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQVNIE
Sbjct  130  IDHSVIIDVFGKPDAFERNVEFEYGRNKERYQFLRWGQGAFDEFKVVPPGTGIVHQVNIE  189

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  VM R+G AYPD+CVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV
Sbjct  190  HLARTVMARNGQAYPDSCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  249

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI  G TATDVVLT+TEMLR+HGVVGKFVEFYG GVA VPLANRAT+GNMSPEF
Sbjct  250  GFKLTGEIPAGATATDVVLTITEMLRKHGVVGKFVEFYGSGVASVPLANRATIGNMSPEF  309

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GST AIFPID+ETI+YL+ TGR   QV LVEAYAK QG+WHDP  EP++SEYLEL+LS V
Sbjct  310  GSTCAIFPIDDETIRYLKLTGRDQAQVDLVEAYAKEQGLWHDPSVEPDYSEYLELDLSTV  369

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVG-NGSPDSPHDPHSKLDEVVEETFPASDP  423
            VPSIAGPKRPQDRI ++ AK +FR+ +  YV   G+ D      + LDE  +E+FPASD 
Sbjct  370  VPSIAGPKRPQDRIEVSAAKPSFRKSLTDYVQVTGTADD-----AALDEAGKESFPASDA  424

Query  424  GQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTS  483
              +T   +       VHSAA  ++GR SNP+ VKS+E GEF LDHGAVVIA+ITSCTNTS
Sbjct  425  PSVTHHGE--GDKPVVHSAANGSNGRPSNPILVKSEEYGEFELDHGAVVIASITSCTNTS  482

Query  484  NPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGY  543
            NP VMLGAALLARNAV+KGLT KPWVKT++APGSQVV DYY+++GLWPYLEKLGF+LVGY
Sbjct  483  NPSVMLGAALLARNAVDKGLTRKPWVKTSMAPGSQVVTDYYEKAGLWPYLEKLGFHLVGY  542

Query  544  GCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  603
            GCTTCIGNSGPLPEEIS AV +NDLSVT+VLSGNRNFEGRINPDVKMNYLASPPLVIAYA
Sbjct  543  GCTTCIGNSGPLPEEISAAVQENDLSVTSVLSGNRNFEGRINPDVKMNYLASPPLVIAYA  602

Query  604  LAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDD  663
            LAGTMDFDF   PLG D +G  VFLRDIWPS Q+V  TI +AI QEMFT++Y+DVFKGD+
Sbjct  603  LAGTMDFDFSNDPLGDDTEGNPVFLRDIWPSPQEVQQTIDSAITQEMFTKDYSDVFKGDE  662

Query  664  RWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHIS  723
            RWR+LPTP G TF+WD +STYVRKPPYFEGM  +P PV  I+GARVLALLGDSVTTDHIS
Sbjct  663  RWRSLPTPEGETFDWDADSTYVRKPPYFEGMGMEPAPVEEITGARVLALLGDSVTTDHIS  722

Query  724  PAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGY  783
            PAGAIKP +PA +YL EHG++RKD+NS+GSRRGNHEVMIRGTFANIRLRN LLDDV GGY
Sbjct  723  PAGAIKPDSPAGKYLSEHGIERKDFNSYGSRRGNHEVMIRGTFANIRLRNLLLDDVQGGY  782

Query  784  TRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAE  843
            TRDFTQ GGPQ+FIYDAAQNYAAQ  PLVV GGKEYGSGSSRDWAAKGT LLGVRAVIAE
Sbjct  783  TRDFTQEGGPQSFIYDAAQNYAAQGTPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAE  842

Query  844  SFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK  903
            SFERIHRSNLIGMGVIPLQFPEG SA SLGLDGTE +D +GI  LNDG+TP+TV V A K
Sbjct  843  SFERIHRSNLIGMGVIPLQFPEGSSAKSLGLDGTETYDFSGITKLNDGETPETVKVTARK  902

Query  904  GDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKS  942
             DG+T+EFDA VRIDTPGEADYYRNGGILQYVLR +++S
Sbjct  903  ADGSTVEFDAKVRIDTPGEADYYRNGGILQYVLRKMIRS  941


>gi|331697181|ref|YP_004333420.1| aconitate hydratase 1 [Pseudonocardia dioxanivorans CB1190]
 gi|326951870|gb|AEA25567.1| aconitate hydratase 1 [Pseudonocardia dioxanivorans CB1190]
Length=939

 Score = 1451 bits (3755),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 721/941 (77%), Positives = 808/941 (86%), Gaps = 11/941 (1%)

Query  5    SVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAI  64
            S +SFGA  TL VGE  Y+I+RL AV    KLPYSLKVL ENLLR EDG+N+T DHI A+
Sbjct  3    STDSFGARGTLDVGENQYEIFRLAAVEGAEKLPYSLKVLLENLLRTEDGANVTADHIRAL  62

Query  65   ANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLV  124
            A WDP A+P  EIQ+TPARV+MQDFTGVPC+VDLATMREA+ ++GG+P KVNPLAPA+LV
Sbjct  63   AAWDPAADPDTEIQFTPARVIMQDFTGVPCVVDLATMREAVTEMGGDPAKVNPLAPAELV  122

Query  125  IDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIE  184
            IDHSV+ D FG ADAFE+N+E EY RN ERYQFLRWGQGAFD+FKVVPPGTGIVHQVNIE
Sbjct  123  IDHSVMIDFFGTADAFEKNIEFEYGRNQERYQFLRWGQGAFDEFKVVPPGTGIVHQVNIE  182

Query  185  YLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVV  244
            +LA  VM R+G AYPDT VGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIP+V+
Sbjct  183  HLARTVMARNGQAYPDTLVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPKVL  242

Query  245  GFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEF  304
            GF+LTGEI  GVTATDVVLT+TEMLR+ GVVGKFVEFYG GV+ VPLANRAT+GNMSPEF
Sbjct  243  GFKLTGEIPAGVTATDVVLTITEMLRRQGVVGKFVEFYGAGVSAVPLANRATIGNMSPEF  302

Query  305  GSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDV  364
            GSTAAIFPID+ET++YL+ TGR+ EQ+ALVEAYAK QG+WHDP  EP FSE LEL+LS V
Sbjct  303  GSTAAIFPIDDETVRYLKLTGRSAEQIALVEAYAKEQGLWHDPAAEPVFSETLELDLSTV  362

Query  365  VPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPG  424
            VPSI+GPKRPQDRI L  AK+ FR  +  Y    + D+  +P S +DE  +E+FPASD  
Sbjct  363  VPSISGPKRPQDRIELTAAKAAFRAAVQDY----TDDAVVEPLSGVDESSDESFPASDAP  418

Query  425  QLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSN  484
              +    + A    V SAA   +GR S P  V S   GEFVLDHGAVVIA+ITSCTNTSN
Sbjct  419  ATSTHGHEAA--PVVFSAADGCEGRPSKPTTVTSASRGEFVLDHGAVVIASITSCTNTSN  476

Query  485  PEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYG  544
            P VMLGAALLARNAVEKGLT KPWVKT++APGSQVV DYY+++GLWPYL+KLG+ LVGYG
Sbjct  477  PSVMLGAALLARNAVEKGLTVKPWVKTSMAPGSQVVTDYYEKAGLWPYLDKLGYNLVGYG  536

Query  545  CTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  604
            CTTCIGNSGPLPEEIS AVN+ DLSV +VLSGNRNFEGRINPDVKMNYLASPPLVIAYAL
Sbjct  537  CTTCIGNSGPLPEEISAAVNEADLSVVSVLSGNRNFEGRINPDVKMNYLASPPLVIAYAL  596

Query  605  AGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDR  664
            AGTMDFDF+TQPLG+D DGK+VFL DIWPS +DV+  + AAI++EMF ++Y+DVF+GD+R
Sbjct  597  AGTMDFDFETQPLGKDGDGKDVFLADIWPSTEDVNAVMDAAIDEEMFAKSYSDVFRGDER  656

Query  665  WRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISP  724
            WR+LPTP G TF WDP STYVRKPPYFEGMT +P PV +I+GARVLALLGDSVTTDHISP
Sbjct  657  WRSLPTPEGQTFAWDPASTYVRKPPYFEGMTTEPAPVQDITGARVLALLGDSVTTDHISP  716

Query  725  AGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLD-----DV  779
            AG+IKPGTPAA+YLDE+GVD+KDYNSFGSRRGNHEVMIRGTFANIRLRNQLLD      V
Sbjct  717  AGSIKPGTPAAQYLDENGVDKKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDAIVDGGV  776

Query  780  SGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRA  839
            SGGYTRDFTQ GGPQAFIYDAAQNYAA   PLVV GGKEYGSGSSRDWAAKGT LLGV+A
Sbjct  777  SGGYTRDFTQDGGPQAFIYDAAQNYAAAGTPLVVLGGKEYGSGSSRDWAAKGTALLGVKA  836

Query  840  VIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCV  899
            VI ESFERIHRSNLIGMGVIPLQF +G+SA+SLGLDGTE FDI GI  LNDG TP+T+ V
Sbjct  837  VIVESFERIHRSNLIGMGVIPLQFQQGESAASLGLDGTETFDIAGITALNDGTTPRTLTV  896

Query  900  QATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNIL  940
             ATK DG+TIEFDAVVRIDTPGEADYYRNGGILQYVLR +L
Sbjct  897  TATKEDGSTIEFDAVVRIDTPGEADYYRNGGILQYVLRGML  937



Lambda     K      H
   0.316    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 2342824838764


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40