BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1508A

Length=120
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|57116880|ref|YP_177649.1|  hypothetical protein Rv1508A [Mycob...   248    1e-64
gi|15840977|ref|NP_336014.1|  GDP-D-mannose dehydratase [Mycobact...  68.2    4e-10
gi|289750076|ref|ZP_06509454.1|  LOW QUALITY PROTEIN: GDP-D-manno...  67.8    5e-10
gi|289447121|ref|ZP_06436865.1|  GDP-D-mannose dehydratase gmdA [...  67.8    5e-10
gi|340626530|ref|YP_004744982.1|  GDP-D-mannose dehydratase gmdA ...  67.8    5e-10
gi|15608649|ref|NP_216027.1|  GDP-D-mannose dehydratase gmdA (GDP...  67.8    5e-10
gi|240171768|ref|ZP_04750427.1|  GDP-D-mannose dehydratase [Mycob...  66.6    1e-09
gi|326775975|ref|ZP_08235240.1|  GDP-mannose 4,6-dehydratase [Str...  65.9    2e-09
gi|26546921|gb|AAN05764.1|  GDP-D-mannose-dehydratase MdhtA [Myco...  65.9    2e-09
gi|111022410|ref|YP_705382.1|  GDP-mannose 4,6-dehydratase [Rhodo...  65.5    2e-09
gi|3550473|emb|CAA11571.1|  gsbA [Mycobacterium avium subsp. silv...  65.5    2e-09
gi|182435335|ref|YP_001823054.1|  putative GDP-D-mannose dehydrat...  65.5    2e-09
gi|117927658|ref|YP_872209.1|  GDP-mannose 4,6-dehydratase [Acido...  65.5    2e-09
gi|3550478|emb|CAA11575.1|  gsbA [Mycobacterium avium subsp. para...  65.5    2e-09
gi|41407329|ref|NP_960165.1|  GmdA [Mycobacterium avium subsp. pa...  65.5    3e-09
gi|254775706|ref|ZP_05217222.1|  GmdA [Mycobacterium avium subsp....  65.5    3e-09
gi|226334852|ref|YP_002784524.1|  GDP-mannose 4,6-dehydratase [Rh...  65.1    4e-09
gi|152965793|ref|YP_001361577.1|  GDP-mannose 4,6-dehydratase [Ki...  65.1    4e-09
gi|345002640|ref|YP_004805494.1|  GDP-mannose 4,6-dehydratase [St...  64.7    4e-09
gi|119960832|ref|YP_949780.1|  GDP-mannose 4,6-dehydratase [Arthr...  64.3    6e-09
gi|320007946|gb|ADW02796.1|  GDP-mannose 4,6-dehydratase [Strepto...  63.9    7e-09
gi|108797919|ref|YP_638116.1|  GDP-mannose 4,6-dehydratase [Mycob...  63.9    7e-09
gi|229492398|ref|ZP_04386205.1|  GDP-mannose 4,6-dehydratase [Rho...  63.9    8e-09
gi|206890367|ref|YP_002248314.1|  GDP-mannose 4,6-dehydratase [Th...  63.5    1e-08
gi|238928051|ref|ZP_04659811.1|  GDP-mannose 4,6-dehydratase [Sel...  63.5    1e-08
gi|229492317|ref|ZP_04386124.1|  GDP-mannose 4,6-dehydratase [Rho...  63.5    1e-08
gi|226304813|ref|YP_002764771.1|  GDP-mannose 4,6-dehydratase [Rh...  63.5    1e-08
gi|145225332|ref|YP_001136010.1|  GDP-mannose 4,6-dehydratase [My...  63.5    1e-08
gi|239991460|ref|ZP_04712124.1|  putative GDP-D-mannose dehydrata...  63.2    1e-08
gi|284030676|ref|YP_003380607.1|  GDP-mannose 4,6-dehydratase [Kr...  63.2    1e-08
gi|296140313|ref|YP_003647556.1|  GDP-mannose 4,6-dehydratase [Ts...  63.2    1e-08
gi|320530309|ref|ZP_08031377.1|  GDP-mannose 4,6-dehydratase [Sel...  62.8    1e-08
gi|313895297|ref|ZP_07828854.1|  GDP-mannose 4,6-dehydratase [Sel...  62.8    2e-08
gi|302537023|ref|ZP_07289365.1|  GDP-mannose 4,6-dehydratase [Str...  62.4    2e-08
gi|311746684|ref|ZP_07720469.1|  GDP-mannose 4,6-dehydratase [Alg...  62.4    2e-08
gi|15076985|gb|AAK83010.1|AF285969_2  GDP-D-mannose dehydratase G...  62.0    3e-08
gi|194428784|ref|ZP_03061320.1|  GDP-mannose 4,6-dehydratase [Esc...  62.0    3e-08
gi|83744452|gb|ABC42542.1|  putative mannose dehydratase [Strepto...  62.0    3e-08
gi|332711566|ref|ZP_08431497.1|  GDP-mannose 4,6-dehydratase [Lyn...  62.0    3e-08
gi|33239515|ref|NP_874457.1|  GDP-D-mannose dehydratase [Prochlor...  62.0    3e-08
gi|224373676|ref|YP_002608048.1|  GDP-mannose 4,6-dehydratase [Na...  61.6    3e-08
gi|193069311|ref|ZP_03050267.1|  GDP-mannose 4,6-dehydratase [Esc...  61.6    3e-08
gi|323650603|gb|ADX97399.1|  GDP-mannose 4,6-dehydratase [Yersini...  61.6    4e-08
gi|166226992|dbj|BAG06237.1|  GDP-mannose-4,6-dehydratase [Escher...  61.6    4e-08
gi|88802224|ref|ZP_01117751.1|  GDP-D-mannose dehydratase [Polari...  61.6    4e-08
gi|332184329|gb|AEE26583.1|  GDP-mannose-4,6-dehydratase [Francis...  61.6    4e-08
gi|302038311|ref|YP_003798633.1|  GDP-mannose 4,6-dehydratase [Ca...  61.6    4e-08
gi|334127343|ref|ZP_08501270.1|  GDP-mannose 4,6-dehydratase [Cen...  61.6    4e-08
gi|170781973|ref|YP_001710305.1|  GDP-mannose 4,6-dehydratase [Cl...  61.6    4e-08
gi|148272781|ref|YP_001222342.1|  putative GDP-mannose 4,6-dehydr...  61.6    4e-08


>gi|57116880|ref|YP_177649.1| hypothetical protein Rv1508A [Mycobacterium tuberculosis H37Rv]
 gi|148661304|ref|YP_001282827.1| hypothetical protein MRA_1520 [Mycobacterium tuberculosis H37Ra]
 gi|148822731|ref|YP_001287486.1| hypothetical protein TBFG_11541 [Mycobacterium tuberculosis F11]
 49 more sequence titles
 Length=120

 Score =  248 bits (634),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 119/120 (99%), Positives = 120/120 (100%), Gaps = 0/120 (0%)

Query  1    VKRALITGITGPDGSYLAKLPLKGYVAAGSPAEVYFCWATRNYRELYGLLAVNSIWFNHE  60
            +KRALITGITGPDGSYLAKLPLKGYVAAGSPAEVYFCWATRNYRELYGLLAVNSIWFNHE
Sbjct  1    MKRALITGITGPDGSYLAKLPLKGYVAAGSPAEVYFCWATRNYRELYGLLAVNSIWFNHE  60

Query  61   SPRHGETFMTRNPAPYRGRQRGADRCADADAPAHPDRYQYWGVPASVRGVIDRAMGVCVE  120
            SPRHGETFMTRNPAPYRGRQRGADRCADADAPAHPDRYQYWGVPASVRGVIDRAMGVCVE
Sbjct  61   SPRHGETFMTRNPAPYRGRQRGADRCADADAPAHPDRYQYWGVPASVRGVIDRAMGVCVE  120


>gi|15840977|ref|NP_336014.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis CDC1551]
 gi|253799433|ref|YP_003032434.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis KZN 
1435]
 gi|254231741|ref|ZP_04925068.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis C]
 gi|294996480|ref|ZP_06802171.1| GDP-mannose 4,6-dehydratase [Mycobacterium tuberculosis 210]
 gi|297731066|ref|ZP_06960184.1| GDP-mannose 4,6-dehydratase [Mycobacterium tuberculosis KZN R506]
 gi|13881184|gb|AAK45828.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis CDC1551]
 gi|124600800|gb|EAY59810.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis C]
 gi|253320936|gb|ACT25539.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis KZN 
1435]
Length=348

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 31/41 (76%), Positives = 33/41 (81%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WATRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  164  AKVYSYWATRNYREAYGLFAVNGILFNHESPRRGETFVTRK  204


 Score = 41.6 bits (96),  Expect = 0.035, Method: Compositional matrix adjust.
 Identities = 23/30 (77%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           VKRALITGITG DGSYLA+L L KGY   G
Sbjct  9   VKRALITGITGQDGSYLAELLLAKGYEVHG  38


>gi|289750076|ref|ZP_06509454.1| LOW QUALITY PROTEIN: GDP-D-mannose dehydratase gmdA [Mycobacterium 
tuberculosis T92]
 gi|289690663|gb|EFD58092.1| LOW QUALITY PROTEIN: GDP-D-mannose dehydratase gmdA [Mycobacterium 
tuberculosis T92]
Length=341

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 31/41 (76%), Positives = 33/41 (81%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WATRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWATRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.073, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLAKGYEVHG  30


>gi|289447121|ref|ZP_06436865.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis CPHL_A]
 gi|289420079|gb|EFD17280.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis CPHL_A]
Length=340

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 31/41 (76%), Positives = 33/41 (81%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WATRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWATRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.080, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLAKGYEVHG  30


>gi|340626530|ref|YP_004744982.1| GDP-D-mannose dehydratase gmdA [Mycobacterium canettii CIPT 140010059]
 gi|340004720|emb|CCC43864.1| GDP-D-mannose dehydratase gmdA (GDP-mannose 4,6 dehydratase) 
(GMD) [Mycobacterium canettii CIPT 140010059]
Length=340

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 31/41 (76%), Positives = 33/41 (81%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WATRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWATRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.076, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLAKGYEVHG  30


>gi|15608649|ref|NP_216027.1| GDP-D-mannose dehydratase gmdA (GDP-mannose 4,6 dehydratase) 
(GMD) [Mycobacterium tuberculosis H37Rv]
 gi|148661307|ref|YP_001282830.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis H37Ra]
 gi|148822736|ref|YP_001287490.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis F11]
 57 more sequence titles
 Length=340

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 31/41 (76%), Positives = 33/41 (81%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WATRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWATRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.076, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLAKGYEVHG  30


>gi|240171768|ref|ZP_04750427.1| GDP-D-mannose dehydratase [Mycobacterium kansasii ATCC 12478]
Length=344

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 30/41 (74%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWVTRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.071, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|326775975|ref|ZP_08235240.1| GDP-mannose 4,6-dehydratase [Streptomyces cf. griseus XylebKG-1]
 gi|326656308|gb|EGE41154.1| GDP-mannose 4,6-dehydratase [Streptomyces griseus XylebKG-1]
Length=353

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 30/43 (70%), Positives = 33/43 (77%), Gaps = 0/43 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            S A+VY  WAT NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  171  SVAKVYAYWATVNYREAYGMFAVNGILFNHESPRRGETFVTRK  213


 Score = 38.1 bits (87),  Expect = 0.38, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYLA+L L KGY   G
Sbjct  19  KTALITGVTGQDGSYLAELLLDKGYTVHG  47


>gi|26546921|gb|AAN05764.1| GDP-D-mannose-dehydratase MdhtA [Mycobacterium avium]
Length=340

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWVTRNYREAYGMFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.085, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|111022410|ref|YP_705382.1| GDP-mannose 4,6-dehydratase [Rhodococcus jostii RHA1]
 gi|110821940|gb|ABG97224.1| GDP-mannose 4,6-dehydratase [Rhodococcus jostii RHA1]
Length=376

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  190  AKVYSYWVTRNYREAYGMFAVNGILFNHESPRRGETFVTRK  230


 Score = 40.4 bits (93),  Expect = 0.079, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  35  LKRALITGITGQDGSYLAELLLAKGYEVHG  64


>gi|3550473|emb|CAA11571.1| gsbA [Mycobacterium avium subsp. silvaticum]
Length=343

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+V+  W TRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVFSYWTTRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.089, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|182435335|ref|YP_001823054.1| putative GDP-D-mannose dehydratase [Streptomyces griseus subsp. 
griseus NBRC 13350]
 gi|178463851|dbj|BAG18371.1| putative GDP-D-mannose dehydratase [Streptomyces griseus subsp. 
griseus NBRC 13350]
Length=337

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 30/43 (70%), Positives = 33/43 (77%), Gaps = 0/43 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            S A+VY  WAT NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  155  SVAKVYAYWATVNYREAYGMFAVNGILFNHESPRRGETFVTRK  197


 Score = 38.1 bits (87),  Expect = 0.39, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYLA+L L KGY   G
Sbjct  3   KTALITGVTGQDGSYLAELLLDKGYTVHG  31


>gi|117927658|ref|YP_872209.1| GDP-mannose 4,6-dehydratase [Acidothermus cellulolyticus 11B]
 gi|117648121|gb|ABK52223.1| GDP-mannose 4,6-dehydratase [Acidothermus cellulolyticus 11B]
Length=380

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 30/41 (74%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  WAT NYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  200  AKVYAYWATVNYREAYGLFAVNGILFNHESPRRGETFVTRK  240


 Score = 38.9 bits (89),  Expect = 0.29, Method: Compositional matrix adjust.
 Identities = 21/29 (73%), Positives = 23/29 (80%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +RALITGITG DGSYLA+L L KGY   G
Sbjct  46  RRALITGITGQDGSYLAELLLAKGYEVHG  74


>gi|3550478|emb|CAA11575.1| gsbA [Mycobacterium avium subsp. paratuberculosis]
Length=343

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+V+  W TRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVFSYWTTRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.091, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|41407329|ref|NP_960165.1| GmdA [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|41395681|gb|AAS03548.1| GmdA [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|336457965|gb|EGO36953.1| GDP-mannose 4,6-dehydratase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=343

 Score = 65.5 bits (158),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+V+  W TRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVFSYWTTRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.089, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|254775706|ref|ZP_05217222.1| GmdA [Mycobacterium avium subsp. avium ATCC 25291]
 gi|5524326|gb|AAD44219.1|AF143772_25 mdhtA [Mycobacterium avium]
 gi|4416473|gb|AAD20373.1| GDP-D-mannose-dehydratase mdhtA [Mycobacterium avium]
Length=343

 Score = 65.5 bits (158),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+V+  W TRNYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVFSYWTTRNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.092, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|226334852|ref|YP_002784524.1| GDP-mannose 4,6-dehydratase [Rhodococcus opacus B4]
 gi|226246072|dbj|BAH56172.1| GDP-mannose 4,6-dehydratase [Rhodococcus opacus B4]
Length=342

 Score = 65.1 bits (157),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T+NYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWVTKNYREAYGLFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.4 bits (93),  Expect = 0.082, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLRKGYEVHG  30


>gi|152965793|ref|YP_001361577.1| GDP-mannose 4,6-dehydratase [Kineococcus radiotolerans SRS30216]
 gi|151360310|gb|ABS03313.1| GDP-mannose 4,6-dehydratase [Kineococcus radiotolerans SRS30216]
Length=330

 Score = 65.1 bits (157),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  157  AKVYGYWMTRNYREAYGMFAVNGILFNHESPRRGETFVTRK  197


 Score = 38.5 bits (88),  Expect = 0.36, Method: Compositional matrix adjust.
 Identities = 21/29 (73%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+L L KGY   G
Sbjct  3   KTALITGITGQDGSYLAELLLEKGYEVHG  31


>gi|345002640|ref|YP_004805494.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SirexAA-E]
 gi|344318266|gb|AEN12954.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SirexAA-E]
Length=337

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 30/43 (70%), Positives = 33/43 (77%), Gaps = 0/43 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            S A+VY  WAT NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  155  SVAKVYAYWATVNYREAYGMYAVNGILFNHESPRRGETFVTRK  197


 Score = 37.0 bits (84),  Expect = 0.91, Method: Compositional matrix adjust.
 Identities = 19/29 (66%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYL++L L KGY   G
Sbjct  3   KTALITGVTGQDGSYLSELLLDKGYTVHG  31


>gi|119960832|ref|YP_949780.1| GDP-mannose 4,6-dehydratase [Arthrobacter aurescens TC1]
 gi|119947691|gb|ABM06602.1| GDP-mannose 4,6-dehydratase [Arthrobacter aurescens TC1]
Length=345

 Score = 64.3 bits (155),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  157  AKVYSYWMTKNYREAYGMFAVNGILFNHESPRRGETFVTRK  197


 Score = 39.3 bits (90),  Expect = 0.17, Method: Compositional matrix adjust.
 Identities = 21/29 (73%), Positives = 23/29 (80%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K+ALITGITG DGSYLA+L L KGY   G
Sbjct  3   KKALITGITGQDGSYLAELLLSKGYEVHG  31


>gi|320007946|gb|ADW02796.1| GDP-mannose 4,6-dehydratase [Streptomyces flavogriseus ATCC 33331]
Length=337

 Score = 63.9 bits (154),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 29/43 (68%), Positives = 32/43 (75%), Gaps = 0/43 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            S A+VY  WAT NYRE YG+ A N I FNHESPR GETF+TR 
Sbjct  155  SVAKVYSYWATVNYREAYGMFATNGILFNHESPRRGETFVTRK  197


 Score = 37.4 bits (85),  Expect = 0.74, Method: Compositional matrix adjust.
 Identities = 19/29 (66%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYL++L L KGY   G
Sbjct  3   KTALITGVTGQDGSYLSELLLEKGYTVHG  31


>gi|108797919|ref|YP_638116.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. MCS]
 gi|119867015|ref|YP_936967.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. KMS]
 gi|108768338|gb|ABG07060.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. MCS]
 gi|119693104|gb|ABL90177.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. KMS]
Length=351

 Score = 63.9 bits (154),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YGL AVN I FNHESPR GETF+TR 
Sbjct  157  AKLYSYWITKNYREAYGLFAVNGILFNHESPRRGETFVTRK  197


 Score = 40.0 bits (92),  Expect = 0.10, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
            KRALITGITG DGSYLA+L L KGY   G
Sbjct  2   TKRALITGITGQDGSYLAELLLHKGYEVHG  31


>gi|229492398|ref|ZP_04386205.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121]
 gi|229320807|gb|EEN86621.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121]
Length=343

 Score = 63.9 bits (154),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWITKNYREAYGIFAVNGILFNHESPRRGETFVTRK  196


 Score = 39.3 bits (90),  Expect = 0.18, Method: Compositional matrix adjust.
 Identities = 21/30 (70%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKKALITGITGQDGSYLAELLLGKGYEVHG  30


>gi|206890367|ref|YP_002248314.1| GDP-mannose 4,6-dehydratase [Thermodesulfovibrio yellowstonii 
DSM 11347]
 gi|206742305|gb|ACI21362.1| GDP-mannose 4,6-dehydratase [Thermodesulfovibrio yellowstonii 
DSM 11347]
Length=384

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Composition-based stats.
 Identities = 28/42 (67%), Positives = 31/42 (74%), Gaps = 0/42 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            + A+VY  W T NYRE YGL A N I FNHESPR GETF+TR
Sbjct  154  AAAKVYAYWVTVNYREAYGLFACNGILFNHESPRRGETFVTR  195


 Score = 37.7 bits (86),  Expect = 0.64, Method: Composition-based stats.
 Identities = 20/30 (67%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITGITG DGSYLA+  L KGY   G
Sbjct  1   MKKALITGITGQDGSYLAEFLLSKGYEVHG  30


>gi|238928051|ref|ZP_04659811.1| GDP-mannose 4,6-dehydratase [Selenomonas flueggei ATCC 43531]
 gi|238884011|gb|EEQ47649.1| GDP-mannose 4,6-dehydratase [Selenomonas flueggei ATCC 43531]
Length=353

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 27/41 (66%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  167  AKLYSYWITKNYRESYGMFAVNGILFNHESPRRGETFVTRK  207


 Score = 38.1 bits (87),  Expect = 0.40, Method: Compositional matrix adjust.
 Identities = 20/30 (67%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITGITG DGSYL +L L KGY   G
Sbjct  11  MKKALITGITGQDGSYLTELLLDKGYEVHG  40


>gi|229492317|ref|ZP_04386124.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121]
 gi|229320726|gb|EEN86540.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121]
Length=343

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWITKNYREAYGIFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.072, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|226304813|ref|YP_002764771.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis PR4]
 gi|226183928|dbj|BAH32032.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis PR4]
Length=343

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYSYWITKNYREAYGIFAVNGILFNHESPRRGETFVTRK  196


 Score = 40.8 bits (94),  Expect = 0.075, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA+L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLAELLLSKGYEVHG  30


>gi|145225332|ref|YP_001136010.1| GDP-mannose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
 gi|145217818|gb|ABP47222.1| GDP-mannose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
Length=350

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 27/41 (66%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  157  AKLYSYWITKNYREAYGMFAVNGILFNHESPRRGETFVTRK  197


 Score = 42.0 bits (97),  Expect = 0.033, Method: Compositional matrix adjust.
 Identities = 23/30 (77%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           VKRALITGITG DGSYLA+L L KGY   G
Sbjct  2   VKRALITGITGQDGSYLAELLLSKGYEVHG  31


>gi|239991460|ref|ZP_04712124.1| putative GDP-D-mannose dehydratase [Streptomyces roseosporus 
NRRL 11379]
 gi|291448456|ref|ZP_06587846.1| GDP-mannose 4,6-dehydratase [Streptomyces roseosporus NRRL 15998]
 gi|291351403|gb|EFE78307.1| GDP-mannose 4,6-dehydratase [Streptomyces roseosporus NRRL 15998]
Length=351

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 29/43 (68%), Positives = 32/43 (75%), Gaps = 0/43 (0%)

Query  30   SPAEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            S A+VY  WAT NYRE Y + AVN I FNHESPR GETF+TR 
Sbjct  169  SVAKVYSYWATVNYREAYDMFAVNGILFNHESPRRGETFVTRK  211


 Score = 38.1 bits (87),  Expect = 0.43, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYLA+L L KGY   G
Sbjct  17  KTALITGVTGQDGSYLAELLLDKGYTVHG  45


>gi|284030676|ref|YP_003380607.1| GDP-mannose 4,6-dehydratase [Kribbella flavida DSM 17836]
 gi|283809969|gb|ADB31808.1| GDP-mannose 4,6-dehydratase [Kribbella flavida DSM 17836]
Length=327

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 29/41 (71%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE Y L AVN I FNHESPR GETF+TR 
Sbjct  156  AKVYGYWMTRNYREAYDLFAVNGILFNHESPRRGETFVTRK  196


 Score = 37.7 bits (86),  Expect = 0.51, Method: Compositional matrix adjust.
 Identities = 19/30 (64%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+A +TGITG DGSYLA+L L KGY   G
Sbjct  1   MKKAFVTGITGQDGSYLAELLLAKGYEVHG  30


>gi|296140313|ref|YP_003647556.1| GDP-mannose 4,6-dehydratase [Tsukamurella paurometabola DSM 20162]
 gi|296028447|gb|ADG79217.1| GDP-mannose 4,6-dehydratase [Tsukamurella paurometabola DSM 20162]
Length=342

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W TRNYRE Y + AVN I FNHESPR GETF+TR 
Sbjct  157  AKVYSYWITRNYREAYDMFAVNGILFNHESPRRGETFVTRK  197


 Score = 38.5 bits (88),  Expect = 0.37, Method: Compositional matrix adjust.
 Identities = 21/30 (70%), Positives = 22/30 (74%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
            K ALITGITG DGSYLA+L L KGY   G
Sbjct  2   TKTALITGITGQDGSYLAELLLAKGYEVHG  31


>gi|320530309|ref|ZP_08031377.1| GDP-mannose 4,6-dehydratase [Selenomonas artemidis F0399]
 gi|320137452|gb|EFW29366.1| GDP-mannose 4,6-dehydratase [Selenomonas artemidis F0399]
Length=354

 Score = 62.8 bits (151),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 27/41 (66%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  168  AKLYSYWITKNYRESYGMFAVNGILFNHESPRRGETFVTRK  208


 Score = 37.7 bits (86),  Expect = 0.57, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K+ALITGITG DGSYL +L L KGY   G
Sbjct  13  KKALITGITGQDGSYLTELLLEKGYEIHG  41


>gi|313895297|ref|ZP_07828854.1| GDP-mannose 4,6-dehydratase [Selenomonas sp. oral taxon 137 str. 
F0430]
 gi|312976192|gb|EFR41650.1| GDP-mannose 4,6-dehydratase [Selenomonas sp. oral taxon 137 str. 
F0430]
Length=343

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 27/41 (66%), Positives = 32/41 (79%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  157  AKLYSYWITKNYRESYGMFAVNGILFNHESPRRGETFVTRK  197


 Score = 38.1 bits (87),  Expect = 0.39, Method: Compositional matrix adjust.
 Identities = 20/30 (67%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITGITG DGSYL +L L KGY   G
Sbjct  1   MKKALITGITGQDGSYLTELLLEKGYEIHG  30


>gi|302537023|ref|ZP_07289365.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. C]
 gi|302445918|gb|EFL17734.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. C]
Length=361

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 27/41 (66%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+V+  W T NYRE YG+ AVN I FNHESPR GETF+TR 
Sbjct  181  AKVFAYWTTVNYREAYGMFAVNGILFNHESPRRGETFVTRK  221


 Score = 38.1 bits (87),  Expect = 0.40, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITG+TG DGSYLA+L L KGY   G
Sbjct  27  KTALITGVTGQDGSYLAELLLSKGYTVHG  55


>gi|311746684|ref|ZP_07720469.1| GDP-mannose 4,6-dehydratase [Algoriphagus sp. PR1]
 gi|126578357|gb|EAZ82521.1| GDP-mannose 4,6-dehydratase [Algoriphagus sp. PR1]
Length=390

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Composition-based stats.
 Identities = 25/40 (63%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T+NYRE Y + A N I FNHESPR GETF+TR
Sbjct  164  AKIYAYWITKNYREAYNMFACNGILFNHESPRRGETFVTR  203


 Score = 39.7 bits (91),  Expect = 0.14, Method: Composition-based stats.
 Identities = 21/30 (70%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K ALITGITG DGSYLA+L L KGY+  G
Sbjct  1   MKTALITGITGQDGSYLAELLLEKGYMVHG  30


>gi|15076985|gb|AAK83010.1|AF285969_2 GDP-D-mannose dehydratase Gmd [Salmonella enterica]
Length=372

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 31/58 (54%), Positives = 37/58 (64%), Gaps = 5/58 (8%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRNPAPYRG---RQRGADRC  86
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR     RG     +G D+C
Sbjct  160  AKLYAYWITVNYRESYGMFACNGILFNHESPRRGETFVTRKIT--RGIANIAQGLDKC  215


 Score = 37.7 bits (86),  Expect = 0.62, Method: Composition-based stats.
 Identities = 21/29 (73%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+L L KGY   G
Sbjct  3   KVALITGITGQDGSYLAELLLEKGYEVHG  31


>gi|194428784|ref|ZP_03061320.1| GDP-mannose 4,6-dehydratase [Escherichia coli B171]
 gi|5678716|gb|AAD46729.1|AF078736_3 GDP-D-mannose dehydratase [Escherichia coli]
 gi|194413231|gb|EDX29517.1| GDP-mannose 4,6-dehydratase [Escherichia coli B171]
Length=372

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 31/58 (54%), Positives = 37/58 (64%), Gaps = 5/58 (8%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRNPAPYRG---RQRGADRC  86
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR     RG     +G D+C
Sbjct  160  AKLYAYWITVNYRESYGMFACNGILFNHESPRRGETFVTRKIT--RGIANIAQGLDKC  215


 Score = 37.7 bits (86),  Expect = 0.64, Method: Composition-based stats.
 Identities = 21/29 (73%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+L L KGY   G
Sbjct  3   KVALITGITGQDGSYLAELLLEKGYEVHG  31


>gi|83744452|gb|ABC42542.1| putative mannose dehydratase [Streptomyces hygroscopicus]
Length=352

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 27/39 (70%), Positives = 30/39 (77%), Gaps = 0/39 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMT  70
            A+VY  W TRNYRE YG+  VN I FNHESPR GETF+T
Sbjct  156  AKVYSYWMTRNYREAYGMFTVNGILFNHESPRRGETFVT  194


 Score = 40.4 bits (93),  Expect = 0.084, Method: Compositional matrix adjust.
 Identities = 22/30 (74%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +KRALITGITG DGSYLA L L KGY   G
Sbjct  1   MKRALITGITGQDGSYLADLLLDKGYEVHG  30


>gi|332711566|ref|ZP_08431497.1| GDP-mannose 4,6-dehydratase [Lyngbya majuscula 3L]
 gi|332349544|gb|EGJ29153.1| GDP-mannose 4,6-dehydratase [Lyngbya majuscula 3L]
Length=383

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 27/40 (68%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A+VY  W T NYRE YG+ A N I FNHESPR GETF+TR
Sbjct  188  AKVYAHWQTINYRESYGMFACNGILFNHESPRRGETFVTR  227


 Score = 39.3 bits (90),  Expect = 0.22, Method: Composition-based stats.
 Identities = 21/29 (73%), Positives = 23/29 (80%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           KRALITGITG DGSYL++L L KGY   G
Sbjct  29  KRALITGITGQDGSYLSELLLEKGYEVHG  57


>gi|33239515|ref|NP_874457.1| GDP-D-mannose dehydratase [Prochlorococcus marinus subsp. marinus 
str. CCMP1375]
 gi|33237040|gb|AAP99109.1| GDP-D-mannose dehydratase [Prochlorococcus marinus subsp. marinus 
str. CCMP1375]
Length=375

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 32/58 (56%), Positives = 36/58 (63%), Gaps = 5/58 (8%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRNPAPYRGRQR---GADRC  86
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR     RG  R   G D C
Sbjct  163  AKLYGYWITVNYREAYGMYACNGILFNHESPRRGETFVTRKIT--RGLARIDAGLDEC  218


 Score = 40.0 bits (92),  Expect = 0.10, Method: Composition-based stats.
 Identities = 22/29 (76%), Positives = 23/29 (80%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+L L KGYV  G
Sbjct  6   KTALITGITGQDGSYLAELLLEKGYVVHG  34


>gi|224373676|ref|YP_002608048.1| GDP-mannose 4,6-dehydratase [Nautilia profundicola AmH]
 gi|223589707|gb|ACM93443.1| GDP-mannose 4,6-dehydratase [Nautilia profundicola AmH]
Length=392

 Score = 61.6 bits (148),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 26/40 (65%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T NYRE Y + AVN I FNHESPR GETF+TR
Sbjct  161  AKMYAYWITVNYREAYNMFAVNGILFNHESPRRGETFVTR  200


 Score = 36.2 bits (82),  Expect = 1.5, Method: Composition-based stats.
 Identities = 20/29 (69%), Positives = 21/29 (73%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+  L KGY   G
Sbjct  4   KVALITGITGQDGSYLAEFLLEKGYEVHG  32


>gi|193069311|ref|ZP_03050267.1| GDP-mannose 4,6-dehydratase [Escherichia coli E110019]
 gi|260868760|ref|YP_003235162.1| GDP-D-mannose dehydratase [Escherichia coli O111:H- str. 11128]
 gi|192957444|gb|EDV87891.1| GDP-mannose 4,6-dehydratase [Escherichia coli E110019]
 gi|257765116|dbj|BAI36611.1| GDP-D-mannose dehydratase [Escherichia coli O111:H- str. 11128]
 gi|323177059|gb|EFZ62649.1| GDP-mannose 4,6-dehydratase [Escherichia coli 1180]
 gi|345338640|gb|EGW71067.1| GDP-mannose 4,6-dehydratase [Escherichia coli 2534-86]
 gi|345354815|gb|EGW87032.1| GDP-mannose 4,6-dehydratase [Escherichia coli 3030-1]
Length=372

 Score = 61.6 bits (148),  Expect = 3e-08, Method: Composition-based stats.
 Identities = 26/40 (65%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR
Sbjct  160  AKLYAYWITVNYRESYGMFACNGILFNHESPRRGETFVTR  199


 Score = 37.7 bits (86),  Expect = 0.64, Method: Composition-based stats.
 Identities = 21/29 (73%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K ALITGITG DGSYLA+L L KGY   G
Sbjct  3   KVALITGITGQDGSYLAELLLEKGYEVHG  31


>gi|323650603|gb|ADX97399.1| GDP-mannose 4,6-dehydratase [Yersinia pseudotuberculosis]
Length=371

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Composition-based stats.
 Identities = 26/40 (65%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR
Sbjct  159  AKLYAYWITVNYREAYGIYACNGILFNHESPRRGETFVTR  198


 Score = 38.1 bits (87),  Expect = 0.47, Method: Composition-based stats.
 Identities = 19/30 (64%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITG+TG DGSYLA+  L KGY   G
Sbjct  1   MKKALITGVTGQDGSYLAEFLLEKGYQVHG  30


>gi|166226992|dbj|BAG06237.1| GDP-mannose-4,6-dehydratase [Escherichia hermannii]
Length=382

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Composition-based stats.
 Identities = 26/40 (65%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR
Sbjct  170  AKMYAYWITVNYREAYGMYACNGILFNHESPRRGETFVTR  209


>gi|88802224|ref|ZP_01117751.1| GDP-D-mannose dehydratase [Polaribacter irgensii 23-P]
 gi|88781082|gb|EAR12260.1| GDP-D-mannose dehydratase [Polaribacter irgensii 23-P]
Length=375

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Composition-based stats.
 Identities = 25/40 (63%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T+NYRE Y + A N I FNHESPR GETF+TR
Sbjct  164  AKIYGFWITKNYREAYNMFACNGILFNHESPRRGETFVTR  203


 Score = 38.9 bits (89),  Expect = 0.25, Method: Composition-based stats.
 Identities = 21/30 (70%), Positives = 24/30 (80%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K ALITGITG DGSYLA+L L KGY+  G
Sbjct  1   MKVALITGITGQDGSYLAELLLGKGYMVHG  30


>gi|332184329|gb|AEE26583.1| GDP-mannose-4,6-dehydratase [Francisella cf. novicida 3523]
Length=372

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Composition-based stats.
 Identities = 26/40 (65%), Positives = 30/40 (75%), Gaps = 0/40 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTR  71
            A++Y  W T NYRE YG+ A N I FNHESPR GETF+TR
Sbjct  159  AKLYAYWITVNYREAYGIYACNGILFNHESPRRGETFVTR  198


 Score = 38.5 bits (88),  Expect = 0.35, Method: Composition-based stats.
 Identities = 20/30 (67%), Positives = 23/30 (77%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ALITGITG DGSYLA+  L KGY   G
Sbjct  1   MKKALITGITGQDGSYLAEFLLEKGYEVHG  30


>gi|302038311|ref|YP_003798633.1| GDP-mannose 4,6-dehydratase [Candidatus Nitrospira defluvii]
 gi|300606375|emb|CBK42708.1| GDP-mannose 4,6-dehydratase [Candidatus Nitrospira defluvii]
Length=335

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 28/41 (69%), Positives = 30/41 (74%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A+VY  W T NYRE YGL A N I FNHESPR GETF+TR 
Sbjct  156  AKVYAHWITVNYREAYGLFACNGILFNHESPRRGETFVTRK  196


 Score = 34.3 bits (77),  Expect = 5.8, Method: Compositional matrix adjust.
 Identities = 19/27 (71%), Positives = 20/27 (75%), Gaps = 1/27 (3%)

Query  4   ALITGITGPDGSYLAKLPL-KGYVAAG  29
           ALITGITG DGSYLA+  L KGY   G
Sbjct  3   ALITGITGQDGSYLAEFLLAKGYDVYG  29


>gi|334127343|ref|ZP_08501270.1| GDP-mannose 4,6-dehydratase [Centipeda periodontii DSM 2778]
 gi|333389696|gb|EGK60855.1| GDP-mannose 4,6-dehydratase [Centipeda periodontii DSM 2778]
Length=343

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 26/41 (64%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE YG+ A N I FNHESPR GETF+TR 
Sbjct  157  AKLYSFWITKNYRESYGMFACNGILFNHESPRRGETFVTRK  197


 Score = 37.4 bits (85),  Expect = 0.71, Method: Compositional matrix adjust.
 Identities = 19/30 (64%), Positives = 22/30 (74%), Gaps = 1/30 (3%)

Query  1   VKRALITGITGPDGSYLAKLPL-KGYVAAG  29
           +K+ LITGITG DGSYL +L L KGY   G
Sbjct  1   MKKVLITGITGQDGSYLTELLLEKGYEVHG  30


>gi|170781973|ref|YP_001710305.1| GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. 
sepedonicus]
 gi|169156541|emb|CAQ01692.1| GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. 
sepedonicus]
Length=350

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 26/41 (64%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE Y + AVN I FNHESPR GETF+TR 
Sbjct  157  AKLYSFWITKNYREAYDMFAVNGILFNHESPRRGETFVTRK  197


 Score = 38.1 bits (87),  Expect = 0.49, Method: Compositional matrix adjust.
 Identities = 20/29 (69%), Positives = 22/29 (76%), Gaps = 1/29 (3%)

Query  2   KRALITGITGPDGSYLAKLPL-KGYVAAG  29
           K+A ITGITG DGSYLA+L L KGY   G
Sbjct  3   KKAFITGITGQDGSYLAELLLAKGYEVHG  31


>gi|148272781|ref|YP_001222342.1| putative GDP-mannose 4,6-dehydratase [Clavibacter michiganensis 
subsp. michiganensis NCPPB 382]
 gi|147830711|emb|CAN01651.1| putative GDP-mannose 4,6-dehydratase [Clavibacter michiganensis 
subsp. michiganensis NCPPB 382]
Length=350

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 26/41 (64%), Positives = 31/41 (76%), Gaps = 0/41 (0%)

Query  32   AEVYFCWATRNYRELYGLLAVNSIWFNHESPRHGETFMTRN  72
            A++Y  W T+NYRE Y + AVN I FNHESPR GETF+TR 
Sbjct  157  AKLYSFWITKNYREAYDMFAVNGILFNHESPRRGETFVTRK  197



Lambda     K      H
   0.322    0.138    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 128530997826


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40