BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1511 Length=340 Score E Sequences producing significant alignments: (Bits) Value gi|15840977|ref|NP_336014.1| GDP-D-mannose dehydratase [Mycobact... 704 0.0 gi|15608649|ref|NP_216027.1| GDP-D-mannose dehydratase gmdA (GDP... 704 0.0 gi|340626530|ref|YP_004744982.1| GDP-D-mannose dehydratase gmdA ... 701 0.0 gi|289447121|ref|ZP_06436865.1| GDP-D-mannose dehydratase gmdA [... 700 0.0 gi|289750076|ref|ZP_06509454.1| LOW QUALITY PROTEIN: GDP-D-manno... 695 0.0 gi|254775706|ref|ZP_05217222.1| GmdA [Mycobacterium avium subsp.... 639 0.0 gi|3550473|emb|CAA11571.1| gsbA [Mycobacterium avium subsp. silv... 637 0.0 gi|41407329|ref|NP_960165.1| GmdA [Mycobacterium avium subsp. pa... 637 0.0 gi|3550478|emb|CAA11575.1| gsbA [Mycobacterium avium subsp. para... 635 4e-180 gi|240171768|ref|ZP_04750427.1| GDP-D-mannose dehydratase [Mycob... 630 6e-179 gi|26546921|gb|AAN05764.1| GDP-D-mannose-dehydratase MdhtA [Myco... 630 1e-178 gi|296140313|ref|YP_003647556.1| GDP-mannose 4,6-dehydratase [Ts... 589 2e-166 gi|226334852|ref|YP_002784524.1| GDP-mannose 4,6-dehydratase [Rh... 589 3e-166 gi|229492398|ref|ZP_04386205.1| GDP-mannose 4,6-dehydratase [Rho... 588 5e-166 gi|111022410|ref|YP_705382.1| GDP-mannose 4,6-dehydratase [Rhodo... 585 4e-165 gi|226304813|ref|YP_002764771.1| GDP-mannose 4,6-dehydratase [Rh... 577 1e-162 gi|229492317|ref|ZP_04386124.1| GDP-mannose 4,6-dehydratase [Rho... 575 4e-162 gi|184201692|ref|YP_001855899.1| GDP-mannose 4,6-dehydratase [Ko... 568 3e-160 gi|148272781|ref|YP_001222342.1| putative GDP-mannose 4,6-dehydr... 565 4e-159 gi|170781973|ref|YP_001710305.1| GDP-mannose 4,6-dehydratase [Cl... 563 1e-158 gi|145225332|ref|YP_001136010.1| GDP-mannose 4,6-dehydratase [My... 560 1e-157 gi|108797919|ref|YP_638116.1| GDP-mannose 4,6-dehydratase [Mycob... 555 4e-156 gi|323358712|ref|YP_004225108.1| GDP-D-mannose dehydratase [Micr... 551 6e-155 gi|119960832|ref|YP_949780.1| GDP-mannose 4,6-dehydratase [Arthr... 541 4e-152 gi|284030676|ref|YP_003380607.1| GDP-mannose 4,6-dehydratase [Kr... 525 3e-147 gi|117927658|ref|YP_872209.1| GDP-mannose 4,6-dehydratase [Acido... 516 2e-144 gi|239991460|ref|ZP_04712124.1| putative GDP-D-mannose dehydrata... 499 3e-139 gi|302523155|ref|ZP_07275497.1| GDP-mannose 4,6-dehydratase [Str... 499 3e-139 gi|318057299|ref|ZP_07976022.1| putative GDP-D-mannose dehydrata... 499 4e-139 gi|326775975|ref|ZP_08235240.1| GDP-mannose 4,6-dehydratase [Str... 495 4e-138 gi|182435335|ref|YP_001823054.1| putative GDP-D-mannose dehydrat... 494 7e-138 gi|320007946|gb|ADW02796.1| GDP-mannose 4,6-dehydratase [Strepto... 494 8e-138 gi|254382404|ref|ZP_04997764.1| GDP-mannose 4,6-dehydratase [Str... 493 2e-137 gi|345002640|ref|YP_004805494.1| GDP-mannose 4,6-dehydratase [St... 488 6e-136 gi|119718422|ref|YP_925387.1| GDP-mannose 4,6-dehydratase [Nocar... 488 8e-136 gi|302537023|ref|ZP_07289365.1| GDP-mannose 4,6-dehydratase [Str... 487 1e-135 gi|83744452|gb|ABC42542.1| putative mannose dehydratase [Strepto... 487 1e-135 gi|152965793|ref|YP_001361577.1| GDP-mannose 4,6-dehydratase [Ki... 475 4e-132 gi|196230860|ref|ZP_03129721.1| GDP-mannose 4,6-dehydratase [Cht... 469 4e-130 gi|312194091|ref|YP_004014152.1| GDP-mannose 4,6-dehydratase [Fr... 468 5e-130 gi|4097914|gb|AAD10232.1| putative GDP-D-mannose dehydratase [An... 467 1e-129 gi|320160406|ref|YP_004173630.1| GDP-mannose 4,6-dehydratase [An... 466 2e-129 gi|218440329|ref|YP_002378658.1| GDP-mannose 4,6-dehydratase [Cy... 465 4e-129 gi|159027653|emb|CAO89517.1| unnamed protein product [Microcysti... 461 5e-128 gi|334117521|ref|ZP_08491612.1| GDP-mannose 4,6-dehydratase [Mic... 461 5e-128 gi|225165868|ref|ZP_03727642.1| GDP-mannose 4,6-dehydratase [Opi... 460 1e-127 gi|300865719|ref|ZP_07110483.1| GDP-mannose 4,6-dehydratase [Osc... 459 4e-127 gi|206890367|ref|YP_002248314.1| GDP-mannose 4,6-dehydratase [Th... 458 4e-127 gi|345303818|ref|YP_004825720.1| GDP-mannose 4,6-dehydratase [Rh... 458 5e-127 gi|254424664|ref|ZP_05038382.1| GDP-mannose 4,6-dehydratase [Syn... 458 7e-127 >gi|15840977|ref|NP_336014.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis CDC1551] gi|253799433|ref|YP_003032434.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis KZN 1435] gi|254231741|ref|ZP_04925068.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis C] gi|294996480|ref|ZP_06802171.1| GDP-mannose 4,6-dehydratase [Mycobacterium tuberculosis 210] gi|297731066|ref|ZP_06960184.1| GDP-mannose 4,6-dehydratase [Mycobacterium tuberculosis KZN R506] gi|13881184|gb|AAK45828.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis CDC1551] gi|124600800|gb|EAY59810.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis C] gi|253320936|gb|ACT25539.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis KZN 1435] Length=348 Score = 704 bits (1818), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/340 (100%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 9 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 68 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR Sbjct 69 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 128 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL Sbjct 129 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 188 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD Sbjct 189 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 248 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL Sbjct 249 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 308 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT Sbjct 309 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 348 >gi|15608649|ref|NP_216027.1| GDP-D-mannose dehydratase gmdA (GDP-mannose 4,6 dehydratase) (GMD) [Mycobacterium tuberculosis H37Rv] gi|148661307|ref|YP_001282830.1| GDP-D-mannose dehydratase [Mycobacterium tuberculosis H37Ra] gi|148822736|ref|YP_001287490.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis F11] 57 more sequence titles Length=340 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/340 (99%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR Sbjct 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL Sbjct 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL Sbjct 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT Sbjct 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 >gi|340626530|ref|YP_004744982.1| GDP-D-mannose dehydratase gmdA [Mycobacterium canettii CIPT 140010059] gi|340004720|emb|CCC43864.1| GDP-D-mannose dehydratase gmdA (GDP-mannose 4,6 dehydratase) (GMD) [Mycobacterium canettii CIPT 140010059] Length=340 Score = 701 bits (1810), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/340 (99%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR Sbjct 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL Sbjct 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYV+GMWRMLQTD Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVDGMWRMLQTD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL Sbjct 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT Sbjct 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 >gi|289447121|ref|ZP_06436865.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis CPHL_A] gi|289420079|gb|EFD17280.1| GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis CPHL_A] Length=340 Score = 700 bits (1806), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/340 (99%), Positives = 339/340 (99%), Gaps = 0/340 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR Sbjct 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL Sbjct 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRML TD Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLPTD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL Sbjct 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT Sbjct 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 >gi|289750076|ref|ZP_06509454.1| LOW QUALITY PROTEIN: GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis T92] gi|289690663|gb|EFD58092.1| LOW QUALITY PROTEIN: GDP-D-mannose dehydratase gmdA [Mycobacterium tuberculosis T92] Length=341 Score = 695 bits (1794), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/336 (99%), Positives = 336/336 (100%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR Sbjct 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL Sbjct 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL Sbjct 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI Sbjct 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 >gi|254775706|ref|ZP_05217222.1| GmdA [Mycobacterium avium subsp. avium ATCC 25291] gi|5524326|gb|AAD44219.1|AF143772_25 mdhtA [Mycobacterium avium] gi|4416473|gb|AAD20373.1| GDP-D-mannose-dehydratase mdhtA [Mycobacterium avium] Length=343 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 301/338 (90%), Positives = 323/338 (96%), Gaps = 0/338 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGL+RRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLVRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Y DL DGTRLVTLLS+I+PDEVYNLAAQSHVRVSFDEPVHTGDTTGMGS+RLLEAVRLSR Sbjct 61 YADLTDGTRLVTLLSSIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQNE TPFYPRSPYGAAKV+SYW TRNYREAYGLFAVNGIL Sbjct 121 VDCRFYQASSSEMFGASPPPQNESTPFYPRSPYGAAKVFSYWTTRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARI+AG+QSEVYMGNLDA+RDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIRAGVQSEVYMGNLDAIRDWGYAPEYVEGMWRMLQAP 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDD+VLATGRG+TVREFA+AAF+H GLDWQ++VKFD RYLRPTEVDSL+GDA KAA+ L Sbjct 241 EPDDYVLATGRGYTVREFAQAAFDHVGLDWQKHVKFDDRYLRPTEVDSLVGDADKAAQSL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAG 338 GW+ASVHT ELARIMVDAD+AALEC+G PWID PM+ G Sbjct 301 GWKASVHTGELARIMVDADIAALECDGTPWIDTPMLPG 338 >gi|3550473|emb|CAA11571.1| gsbA [Mycobacterium avium subsp. silvaticum] Length=343 Score = 637 bits (1643), Expect = 0.0, Method: Compositional matrix adjust. Identities = 301/338 (90%), Positives = 322/338 (96%), Gaps = 0/338 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGL+RRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLVRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Y DL DGTRLVTLLS+I+PDEVYNLAAQSHVRVSFDEPVHTGDTTGMGS+RLLEAVRLSR Sbjct 61 YADLTDGTRLVTLLSSIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQNE TPFYPRSPYGAAKV+SYW TRNYREAYGLFAVNGIL Sbjct 121 VDCRFYQASSSEMFGASPPPQNESTPFYPRSPYGAAKVFSYWTTRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARI+AG+QSEVYMGNLDA+RDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIRAGVQSEVYMGNLDAIRDWGYAPEYVEGMWRMLQAP 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDD+VLATGRG+TVREFA+AAF+H GLDWQ+ VKFD RYLRPTEVDSL+GDA KAA+ L Sbjct 241 EPDDYVLATGRGYTVREFAQAAFDHVGLDWQKRVKFDDRYLRPTEVDSLVGDADKAAQSL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAG 338 GW+ASVHT ELARIMVDAD+AALEC+G PWID PM+ G Sbjct 301 GWKASVHTGELARIMVDADIAALECDGTPWIDTPMLPG 338 >gi|41407329|ref|NP_960165.1| GmdA [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395681|gb|AAS03548.1| GmdA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457965|gb|EGO36953.1| GDP-mannose 4,6-dehydratase [Mycobacterium avium subsp. paratuberculosis S397] Length=343 Score = 637 bits (1643), Expect = 0.0, Method: Compositional matrix adjust. Identities = 300/338 (89%), Positives = 323/338 (96%), Gaps = 0/338 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGL+RRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLVRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Y DL DGTRLVTLLS+I+PDEVYNLAAQSHVRVSFDEPVHTGDTTGMGS+RLLEAVRLSR Sbjct 61 YADLTDGTRLVTLLSSIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQNE TPFYPRSPYGAAKV+SYW TRNYREAYGLFAVNGIL Sbjct 121 VDCRFYQASSSEMFGASPPPQNESTPFYPRSPYGAAKVFSYWTTRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARI+AG+QSEVYMGNLDA+RDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIRAGVQSEVYMGNLDAIRDWGYAPEYVEGMWRMLQAP 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDD+VLATGRG+TVREFA+AAF+H GLDWQ++VKFD RYLRPTEVDSL+GDA +AA+ L Sbjct 241 EPDDYVLATGRGYTVREFAQAAFDHVGLDWQKHVKFDDRYLRPTEVDSLVGDADRAAQSL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAG 338 GW+ASVHT ELARIMVDAD+AALEC+G PWID PM+ G Sbjct 301 GWKASVHTGELARIMVDADIAALECDGTPWIDTPMLPG 338 >gi|3550478|emb|CAA11575.1| gsbA [Mycobacterium avium subsp. paratuberculosis] Length=343 Score = 635 bits (1637), Expect = 4e-180, Method: Compositional matrix adjust. Identities = 299/338 (89%), Positives = 322/338 (96%), Gaps = 0/338 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGL+RRASTFNTSRIDHLYVDPHQPGARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLVRRASTFNTSRIDHLYVDPHQPGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 Y DL DGTRLVTLLS+I+PDEVYNLAAQSHVRVSFDEPVHTGDTTGMGS+RLLEAVRLSR Sbjct 61 YADLTDGTRLVTLLSSIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQNE TPFYPRSPYGAAKV+SYW TRNYREAYGLFAVNGIL Sbjct 121 VDCRFYQASSSEMFGASPPPQNESTPFYPRSPYGAAKVFSYWTTRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARI+AG+QSEVYMGNLDA+RDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIRAGVQSEVYMGNLDAIRDWGYAPEYVEGMWRMLQAP 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDD+VLATGRG+TVREFA+AAF+H GLDWQ++VKFD RYLRPTEVDSL+GDA +AA+ L Sbjct 241 EPDDYVLATGRGYTVREFAQAAFDHVGLDWQKHVKFDDRYLRPTEVDSLVGDADRAAQSL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAG 338 GW+ASVHT ELARIMVDAD+AA EC+G PWID PM+ G Sbjct 301 GWKASVHTGELARIMVDADIAASECDGTPWIDTPMLPG 338 >gi|240171768|ref|ZP_04750427.1| GDP-D-mannose dehydratase [Mycobacterium kansasii ATCC 12478] Length=344 Score = 630 bits (1626), Expect = 6e-179, Method: Compositional matrix adjust. Identities = 298/339 (88%), Positives = 324/339 (96%), Gaps = 0/339 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGLIRRASTFNT+RIDHLYVD H P ARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLIRRASTFNTARIDHLYVDRHDPHARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DGTRLVTLLSTI+PDEVYNLAAQSHVRVSFDEPVHTGDTTGMGS+RLLEA+RLSR Sbjct 61 YGDLTDGTRLVTLLSTIDPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSIRLLEAIRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQ+E TPFYPRSPYGAAKVYSYW TRNYREAYGLFAVNGIL Sbjct 121 VECRFYQASSSEMFGASPPPQSEQTPFYPRSPYGAAKVYSYWVTRNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKI+RAVARIKAG++S VY+GNLDAVRDWGYAPEYV+GMW MLQT Sbjct 181 FNHESPRRGETFVTRKISRAVARIKAGLESHVYLGNLDAVRDWGYAPEYVDGMWGMLQTS 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EP+DFVLATGRG+TVREFA+ AF+HAGLDW+++V+FD+RYLRPTEVDSLIGDATKAA+ L Sbjct 241 EPEDFVLATGRGYTVREFAQTAFDHAGLDWEKHVRFDERYLRPTEVDSLIGDATKAAQSL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGR 339 GW+AS+HT ELARIMVDAD+AALECEGKPWIDKP +A R Sbjct 301 GWKASIHTAELARIMVDADIAALECEGKPWIDKPTLADR 339 >gi|26546921|gb|AAN05764.1| GDP-D-mannose-dehydratase MdhtA [Mycobacterium avium] Length=340 Score = 630 bits (1625), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 299/336 (89%), Positives = 322/336 (96%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGLIRRASTFNT+RIDHLYVDPHQ GARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLIRRASTFNTTRIDHLYVDPHQQGARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DGTRLVTLLSTI+PDEVYNLAAQSHVRVSFDEPV+T DTTGMGS+RLLEAVRLSR Sbjct 61 YGDLTDGTRLVTLLSTIDPDEVYNLAAQSHVRVSFDEPVYTADTTGMGSIRLLEAVRLSR 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYW TRNYREAYG+FAVNGIL Sbjct 121 VECRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWVTRNYREAYGMFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG+QS+VY+GNLDAVRDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGVQSDVYLGNLDAVRDWGYAPEYVEGMWRMLQAP 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATGRG+TVREFA+ AFE AGLDW+++VKFD RYLRPTEVDSLIGDA+KAA L Sbjct 241 EPDDFVLATGRGYTVREFAQTAFERAGLDWERHVKFDDRYLRPTEVDSLIGDASKAARDL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GW+A+VHT ELARIMVDAD+AALEC+G+PWID+P + Sbjct 301 GWKAAVHTGELARIMVDADIAALECDGRPWIDRPNL 336 >gi|296140313|ref|YP_003647556.1| GDP-mannose 4,6-dehydratase [Tsukamurella paurometabola DSM 20162] gi|296028447|gb|ADG79217.1| GDP-mannose 4,6-dehydratase [Tsukamurella paurometabola DSM 20162] Length=342 Score = 589 bits (1519), Expect = 2e-166, Method: Compositional matrix adjust. Identities = 277/338 (82%), Positives = 306/338 (91%), Gaps = 0/338 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 K ALITGITGQDGSYLAELLLAKGYEVHG+IRRASTFNTSRIDHLY D H+ ARLFLH Sbjct 2 TKTALITGITGQDGSYLAELLLAKGYEVHGIIRRASTFNTSRIDHLYQDSHEDDARLFLH 61 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLLS ++PDEVYNLAAQSHVRVSFDEP HTGDTTG+GS RLLEAVR+S+ Sbjct 62 YGDLSDGARLVTLLSEVQPDEVYNLAAQSHVRVSFDEPEHTGDTTGIGSTRLLEAVRMSK 121 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V CRFYQAS+SEMFGA+PPPQNE T FYPRSPYGAAKVYSYW TRNYREAY +FAVNGIL Sbjct 122 VACRFYQASTSEMFGATPPPQNEDTVFYPRSPYGAAKVYSYWITRNYREAYDMFAVNGIL 181 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG+Q +YMGNLDAVRDWGYAPEYVEGMWRMLQ D Sbjct 182 FNHESPRRGETFVTRKITRAVARIKAGVQEHLYMGNLDAVRDWGYAPEYVEGMWRMLQVD 241 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EP+DFVLATG TVREF AF HAGLDW+++V+FD+RYLRPTEVD+LIGDA++AA+LL Sbjct 242 EPNDFVLATGVECTVREFLETAFSHAGLDWERHVRFDERYLRPTEVDALIGDASRAADLL 301 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAG 338 GW+A VH +LARIMVDAD+AA EC G+PWID+P ++G Sbjct 302 GWKAQVHAQQLARIMVDADIAAQECAGRPWIDRPELSG 339 >gi|226334852|ref|YP_002784524.1| GDP-mannose 4,6-dehydratase [Rhodococcus opacus B4] gi|226246072|dbj|BAH56172.1| GDP-mannose 4,6-dehydratase [Rhodococcus opacus B4] Length=342 Score = 589 bits (1518), Expect = 3e-166, Method: Compositional matrix adjust. Identities = 277/334 (83%), Positives = 309/334 (93%), Gaps = 0/334 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL KGYEVHGLIRRAS+FNT+RIDHLYVDPH P ARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLRKGYEVHGLIRRASSFNTARIDHLYVDPHDPEARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL+ I PDEVYNLAAQSHVRVSFDEP HTG+TTG+GS+RLLEAVRL+ Sbjct 61 YGDLSDGARLVTLLAGIRPDEVYNLAAQSHVRVSFDEPEHTGNTTGIGSVRLLEAVRLTG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 ++CR+YQASSSEMFGA+PPPQNE TPFYPRSPYGAAKVYSYW T+NYREAYGLFAVNGIL Sbjct 121 LNCRYYQASSSEMFGATPPPQNEETPFYPRSPYGAAKVYSYWVTKNYREAYGLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG++ +YMGNLDA+RDWGYAPEYVEGMW+MLQ D Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGVEEHLYMGNLDAIRDWGYAPEYVEGMWKMLQAD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATG ++VR+F AFEHAGLDW+++V+FD+RYLRPTEVD+LIGDA+KA E L Sbjct 241 EPDDFVLATGGKYSVRDFLTVAFEHAGLDWEKHVRFDERYLRPTEVDALIGDASKAEEKL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKP 334 GW+A+VHT ELARIMVDAD+ ALE EG+PWID P Sbjct 301 GWKAAVHTPELARIMVDADIRALEHEGRPWIDSP 334 >gi|229492398|ref|ZP_04386205.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121] gi|229320807|gb|EEN86621.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121] Length=343 Score = 588 bits (1515), Expect = 5e-166, Method: Compositional matrix adjust. Identities = 271/336 (81%), Positives = 311/336 (93%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+ALITGITGQDGSYLAELLL KGYEVHGLIRR+STFNT+RIDH+YVDPH P A+LFLH Sbjct 1 MKKALITGITGQDGSYLAELLLGKGYEVHGLIRRSSTFNTARIDHMYVDPHTPDAKLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL+ I PDEVYNLAAQSHVRVSFDEP HTGDTTG+GS+RLLEAVR++ Sbjct 61 YGDLSDGARLVTLLAQIRPDEVYNLAAQSHVRVSFDEPEHTGDTTGIGSIRLLEAVRMAG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + CRFYQASSSEMFGA+PPPQ+E TPFYPRSPYGAAKVYSYW T+NYREAYG+FAVNGIL Sbjct 121 LECRFYQASSSEMFGATPPPQDEQTPFYPRSPYGAAKVYSYWITKNYREAYGIFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG+++++YMGNLDA+RDWGYAPEYVEGMWRMLQ D Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGLENDLYMGNLDAIRDWGYAPEYVEGMWRMLQAD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDD+VLATG ++V++F AFEHAGL+W+ +V+FD+RYLRPTEVD+LIGDA KA + L Sbjct 241 EPDDYVLATGGNYSVKDFLTVAFEHAGLNWEDHVRFDERYLRPTEVDALIGDAGKAEQKL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GW+A+VHT ELARIMVDAD+ AL+CEGKPWID+P + Sbjct 301 GWKATVHTPELARIMVDADIEALKCEGKPWIDRPNL 336 >gi|111022410|ref|YP_705382.1| GDP-mannose 4,6-dehydratase [Rhodococcus jostii RHA1] gi|110821940|gb|ABG97224.1| GDP-mannose 4,6-dehydratase [Rhodococcus jostii RHA1] Length=376 Score = 585 bits (1508), Expect = 4e-165, Method: Compositional matrix adjust. Identities = 275/334 (83%), Positives = 306/334 (92%), Gaps = 0/334 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLLAKGYEVHGLIRR+STFNTSRI+HLYVDPH P A+LFLH Sbjct 35 LKRALITGITGQDGSYLAELLLAKGYEVHGLIRRSSTFNTSRIEHLYVDPHDPAAKLFLH 94 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLLS I+PDEVYNLAAQSHVRVSFDEP HTG+TTG+GS+RLLEAVRL+ Sbjct 95 YGDLSDGARLVTLLSQIQPDEVYNLAAQSHVRVSFDEPEHTGNTTGIGSVRLLEAVRLAG 154 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 ++CR+YQASSSEMFGA+PPPQNE TPFYPRSPYGAAKVYSYW TRNYREAYG+FAVNGIL Sbjct 155 LNCRYYQASSSEMFGATPPPQNEDTPFYPRSPYGAAKVYSYWVTRNYREAYGMFAVNGIL 214 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG++ VYMGNLDA+RDWGYAPEYVEGMWRMLQ D Sbjct 215 FNHESPRRGETFVTRKITRAVARIKAGVEDHVYMGNLDAIRDWGYAPEYVEGMWRMLQAD 274 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 +PDD+ LATG ++VR+F AFEHAGLDW+++V+FD RYLRPTEVD+LIGDA+KA L Sbjct 275 QPDDYCLATGGRYSVRDFLTVAFEHAGLDWEKHVRFDDRYLRPTEVDALIGDASKAEVKL 334 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKP 334 GW+A VHT ELARIMVDAD+ AL EG+PWID P Sbjct 335 GWKARVHTPELARIMVDADIQALAHEGRPWIDSP 368 >gi|226304813|ref|YP_002764771.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis PR4] gi|226183928|dbj|BAH32032.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis PR4] Length=343 Score = 577 bits (1486), Expect = 1e-162, Method: Compositional matrix adjust. Identities = 270/336 (81%), Positives = 305/336 (91%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGLIRR+STFNTSRI+H+YVDPH ARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLIRRSSTFNTSRINHIYVDPHHADARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL+ I+PDEVYNLAAQSHVRVSFDEP HTG+TTG+GS+RLLEAVR++ Sbjct 61 YGDLSDGARLVTLLAQIKPDEVYNLAAQSHVRVSFDEPEHTGNTTGVGSIRLLEAVRMAG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + CRFYQASSSEMFGA+PPPQNE TPFYPRSPYGAAKVYSYW T+NYREAYG+FAVNGIL Sbjct 121 LDCRFYQASSSEMFGATPPPQNEETPFYPRSPYGAAKVYSYWITKNYREAYGIFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAGI+ +YMGNLDA+RDWGYAPEYVEGMWRMLQ D Sbjct 181 FNHESPRRGETFVTRKITRAVARIKAGIEDHLYMGNLDAIRDWGYAPEYVEGMWRMLQVD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EP+DFVLATG ++VR+F AFEHAGL+W+ +V+FD+RYLRPTEVD+LIGD + A L Sbjct 241 EPEDFVLATGGNYSVRDFLTVAFEHAGLNWENHVRFDERYLRPTEVDALIGDPSHAERKL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GW+A VHT ELARIMV+AD+ ALE EG+PWID P + Sbjct 301 GWKAGVHTPELARIMVEADIEALEHEGRPWIDTPAL 336 >gi|229492317|ref|ZP_04386124.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121] gi|229320726|gb|EEN86540.1| GDP-mannose 4,6-dehydratase [Rhodococcus erythropolis SK121] Length=343 Score = 575 bits (1481), Expect = 4e-162, Method: Compositional matrix adjust. Identities = 269/336 (81%), Positives = 304/336 (91%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLAELLL+KGYEVHGLIRR+STFNTSRI+H+YVDPH ARLFLH Sbjct 1 MKRALITGITGQDGSYLAELLLSKGYEVHGLIRRSSTFNTSRINHIYVDPHDADARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL+ I PDEVYNLAAQSHVRVSFDEP HTG+TTG+GS+RLLEAVR++ Sbjct 61 YGDLSDGARLVTLLAQINPDEVYNLAAQSHVRVSFDEPEHTGNTTGVGSIRLLEAVRMAG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + CRFYQASSSEMFGA+PPPQNE TPFYPRSPYGAAKVYSYW T+NYREAYG+FAVNGIL Sbjct 121 LDCRFYQASSSEMFGATPPPQNEETPFYPRSPYGAAKVYSYWITKNYREAYGIFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARI+AGI+ +YMGNLDA+RDWGYAPEYVEGMWRMLQ D Sbjct 181 FNHESPRRGETFVTRKITRAVARIQAGIEDHLYMGNLDAIRDWGYAPEYVEGMWRMLQVD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EP+DFVLATG ++VR+F AFEHAGL+W+ +V+FD+RYLRPTEVD+LIGD + A L Sbjct 241 EPEDFVLATGGNYSVRDFLTVAFEHAGLNWENHVRFDERYLRPTEVDALIGDPSHAERKL 300 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GW+A VHT ELARIMV+AD+ ALE EG+PWID P + Sbjct 301 GWKAGVHTPELARIMVEADIEALEHEGRPWIDTPAL 336 >gi|184201692|ref|YP_001855899.1| GDP-mannose 4,6-dehydratase [Kocuria rhizophila DC2201] gi|183581922|dbj|BAG30393.1| GDP-mannose 4,6-dehydratase [Kocuria rhizophila DC2201] Length=347 Score = 568 bits (1465), Expect = 3e-160, Method: Compositional matrix adjust. Identities = 267/331 (81%), Positives = 296/331 (90%), Gaps = 0/331 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K+ALITGITGQDGSYLAELLL+KGYEVHGLIRRASTFNTSRIDHLY DPH P A+LFLHY Sbjct 4 KKALITGITGQDGSYLAELLLSKGYEVHGLIRRASTFNTSRIDHLYQDPHNPDAQLFLHY 63 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL D RLVTL++ I+PDEVYNLAAQSHVRVSFDEP HTGDTTG+G++RLLEAVR + V Sbjct 64 GDLSDAARLVTLMAEIDPDEVYNLAAQSHVRVSFDEPEHTGDTTGLGTVRLLEAVRRAGV 123 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 CRFYQAS+SE+FGA+PPPQNE TPFYPRSPYGAAK+YSYW T+NYREAY +FAVNGILF Sbjct 124 KCRFYQASTSELFGATPPPQNEDTPFYPRSPYGAAKIYSYWITKNYREAYDMFAVNGILF 183 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVA I AG Q +YMGNLDA+RDWGYA EYVEGMWRMLQ DE Sbjct 184 NHESPRRGETFVTRKITRAVAAIAAGKQEHLYMGNLDAIRDWGYAAEYVEGMWRMLQVDE 243 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P+DFVLATGR TVREF +FEHAGL+W+ +V+FD+RYLRPTEVD+LIGD +KA E LG Sbjct 244 PEDFVLATGRPSTVREFLETSFEHAGLNWEDHVRFDERYLRPTEVDALIGDPSKAEEKLG 303 Query 302 WRASVHTDELARIMVDADMAALECEGKPWID 332 W+A+VH ELARIMVDAD AALEC G PWID Sbjct 304 WKATVHAPELARIMVDADRAALECAGTPWID 334 >gi|148272781|ref|YP_001222342.1| putative GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147830711|emb|CAN01651.1| putative GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=350 Score = 565 bits (1456), Expect = 4e-159, Method: Compositional matrix adjust. Identities = 265/336 (79%), Positives = 297/336 (89%), Gaps = 0/336 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K+A ITGITGQDGSYLAELLLAKGYEVHGLIRR+STFNTSRIDHLY DPH+ GA+LFLHY Sbjct 3 KKAFITGITGQDGSYLAELLLAKGYEVHGLIRRSSTFNTSRIDHLYQDPHEDGAKLFLHY 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL DG+RL TL+ I+PDEVYNLAAQSHVRVSFDEP HT DTTG G++RLLEAVRLS + Sbjct 63 GDLSDGSRLTTLMMQIQPDEVYNLAAQSHVRVSFDEPEHTADTTGTGTIRLLEAVRLSGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 RFYQASSSE++GA+PPPQ+E TPFYPRSPYGAAK+YS+W T+NYREAY +FAVNGILF Sbjct 123 ETRFYQASSSELYGATPPPQSETTPFYPRSPYGAAKLYSFWITKNYREAYDMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVA IKAG Q VY+GNLD++RDWGYA EYVEGMWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVAAIKAGTQDHVYLGNLDSIRDWGYAAEYVEGMWRMLQADE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDDFVLATG FTVR+F AF HAGLDW ++V+FD RYLRPTEVD+L+GDATKA E LG Sbjct 243 PDDFVLATGGNFTVRDFLETAFSHAGLDWSEHVRFDPRYLRPTEVDALVGDATKAHEKLG 302 Query 302 WRASVHTDELARIMVDADMAALECEGKPWIDKPMIA 337 W+A+V T LARIMVDAD+AALE EG+PWID +A Sbjct 303 WKATVDTTMLARIMVDADIAALEAEGRPWIDSVKLA 338 >gi|170781973|ref|YP_001710305.1| GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. sepedonicus] gi|169156541|emb|CAQ01692.1| GDP-mannose 4,6-dehydratase [Clavibacter michiganensis subsp. sepedonicus] Length=350 Score = 563 bits (1452), Expect = 1e-158, Method: Compositional matrix adjust. Identities = 265/336 (79%), Positives = 296/336 (89%), Gaps = 0/336 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K+A ITGITGQDGSYLAELLLAKGYEVHGLIRR+STFNTSRIDHLY DPH+ GA+LFLHY Sbjct 3 KKAFITGITGQDGSYLAELLLAKGYEVHGLIRRSSTFNTSRIDHLYQDPHEDGAKLFLHY 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL DG+RL TL+ I+PDEVYNLAAQSHVRVSFDEP HT DTTG G++RLLEAVRLS + Sbjct 63 GDLSDGSRLTTLMMQIQPDEVYNLAAQSHVRVSFDEPEHTADTTGTGTIRLLEAVRLSGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 RFYQASSSE++GA+PPPQ+E TPFYPRSPYGAAK+YS+W T+NYREAY +FAVNGILF Sbjct 123 ETRFYQASSSELYGATPPPQSETTPFYPRSPYGAAKLYSFWITKNYREAYDMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVA IKAG Q VY+GNLD++RDWGYA EYVEGMWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVAAIKAGKQDHVYLGNLDSIRDWGYAAEYVEGMWRMLQADE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDDFVLATG FTVR+F AF HAGLDW +V+FD RYLRPTEVD+L+GDATKA E LG Sbjct 243 PDDFVLATGGNFTVRDFLETAFSHAGLDWSDHVRFDPRYLRPTEVDALVGDATKAHEKLG 302 Query 302 WRASVHTDELARIMVDADMAALECEGKPWIDKPMIA 337 W+A+V T LARIMVDAD+AALE EG+PWID +A Sbjct 303 WKATVDTTMLARIMVDADIAALEAEGRPWIDTVRLA 338 >gi|145225332|ref|YP_001136010.1| GDP-mannose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK] gi|145217818|gb|ABP47222.1| GDP-mannose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK] Length=350 Score = 560 bits (1443), Expect = 1e-157, Method: Compositional matrix adjust. Identities = 265/333 (80%), Positives = 295/333 (89%), Gaps = 0/333 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 VKRALITGITGQDGSYLAELLL+KGYEVHGLIRRASTFNTSRIDHLYVDPH P A++FLH Sbjct 2 VKRALITGITGQDGSYLAELLLSKGYEVHGLIRRASTFNTSRIDHLYVDPHSPEAKMFLH 61 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL+ I+PDEVYNLAAQSHVRVSFDEP HT DTTG G++RLLEAVRLS Sbjct 62 YGDLSDGARLVTLLADIDPDEVYNLAAQSHVRVSFDEPEHTADTTGTGTIRLLEAVRLSG 121 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 V RFYQASSSE++GA+PPPQNE TPFYPRSPY AK+YSYW T+NYREAYG+FAVNGIL Sbjct 122 VKTRFYQASSSELYGATPPPQNEDTPFYPRSPYAVAKLYSYWITKNYREAYGMFAVNGIL 181 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVA IKAG Q+ +YMGNLDA+RDWGYAPEYVEGMWRMLQ D Sbjct 182 FNHESPRRGETFVTRKITRAVAAIKAGAQNYLYMGNLDAIRDWGYAPEYVEGMWRMLQVD 241 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EPDDFVLATG G TVREF AFEHAGLDW+++V+FD+RYLRPTEVD+LIGD ++AA+ L Sbjct 242 EPDDFVLATGVGITVREFLEVAFEHAGLDWEEHVRFDERYLRPTEVDALIGDPSRAAKKL 301 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDK 333 W +V + +LAR+MVDAD+ A G WIDK Sbjct 302 DWIPTVKSRDLARLMVDADIEAFSHAGTAWIDK 334 >gi|108797919|ref|YP_638116.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. MCS] gi|119867015|ref|YP_936967.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. KMS] gi|108768338|gb|ABG07060.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. MCS] gi|119693104|gb|ABL90177.1| GDP-mannose 4,6-dehydratase [Mycobacterium sp. KMS] Length=351 Score = 555 bits (1430), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 262/336 (78%), Positives = 293/336 (88%), Gaps = 0/336 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 KRALITGITGQDGSYLAELLL KGYEVHGLIRRASTFNT+RIDHLYVDPH P A+LFLH Sbjct 2 TKRALITGITGQDGSYLAELLLHKGYEVHGLIRRASTFNTARIDHLYVDPHSPNAKLFLH 61 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTLL++I PDEVYNLAAQSHVRVSFDEP HT DTTG G++R+LEAVRLS Sbjct 62 YGDLSDGARLVTLLASIRPDEVYNLAAQSHVRVSFDEPEHTADTTGAGTIRMLEAVRLSG 121 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + RFYQASSSE++GA+PPPQNE TPFYPRSPY AAK+YSYW T+NYREAYGLFAVNGIL Sbjct 122 IETRFYQASSSELYGATPPPQNEETPFYPRSPYAAAKLYSYWITKNYREAYGLFAVNGIL 181 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRA A IK+G Q +YMGNLDAVRDWGYAPEYVEGMWRMLQ D Sbjct 182 FNHESPRRGETFVTRKITRAAAAIKSGSQDYLYMGNLDAVRDWGYAPEYVEGMWRMLQVD 241 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 EP+D+VLATG G TVR+F AF H GL W+ +V+FD+RYLRPTEVD+LIGD+T+A E L Sbjct 242 EPNDYVLATGVGITVRDFLEIAFAHVGLRWEDHVRFDERYLRPTEVDALIGDSTRAREKL 301 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWIDKPMI 336 GW +VH LAR+MVDAD+ AL+ EG PW DK ++ Sbjct 302 GWVPTVHGQTLARLMVDADIEALQHEGSPWFDKVLL 337 >gi|323358712|ref|YP_004225108.1| GDP-D-mannose dehydratase [Microbacterium testaceum StLB037] gi|323275083|dbj|BAJ75228.1| GDP-D-mannose dehydratase [Microbacterium testaceum StLB037] Length=350 Score = 551 bits (1420), Expect = 6e-155, Method: Compositional matrix adjust. Identities = 259/332 (79%), Positives = 294/332 (89%), Gaps = 1/332 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 KRALITGITGQDGSYLAELLL+KGYEVHG++RRASTFNT RIDHLY+D H P A+LFLH Sbjct 3 TKRALITGITGQDGSYLAELLLSKGYEVHGIVRRASTFNTHRIDHLYIDSHDPDAKLFLH 62 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG RLVTL+S I PDEVYNLAAQSHVRVSFDEP HT DTTG G++RLLEAVRLS Sbjct 63 YGDLSDGARLVTLMSEINPDEVYNLAAQSHVRVSFDEPEHTADTTGTGTIRLLEAVRLSG 122 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + ++YQAS+SE++GA+PPPQNE TPFYPRSPY AAK+YSYW T+NYREAY +FAVNGIL Sbjct 123 IDTKYYQASTSELYGATPPPQNEETPFYPRSPYAAAKLYSYWITKNYREAYDMFAVNGIL 182 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIKAG+Q+E+Y+GNLD++RDWGYA EYVEGMWRMLQ D Sbjct 183 FNHESPRRGETFVTRKITRAVARIKAGLQNELYLGNLDSIRDWGYAAEYVEGMWRMLQAD 242 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 P+DFVLATG G+T+REF +F HAGLDW+++V+FDQRYLRPTEVD+LIGD TKAAE L Sbjct 243 NPEDFVLATGVGYTIREFLETSFGHAGLDWEEFVRFDQRYLRPTEVDALIGDPTKAAEKL 302 Query 301 GWRASVHTDELARIMVDADMAALECEGKPWID 332 GW SV DELAR+MVDADM AL+ G WID Sbjct 303 GWVPSVRGDELARLMVDADMTALD-RGPEWID 333 >gi|119960832|ref|YP_949780.1| GDP-mannose 4,6-dehydratase [Arthrobacter aurescens TC1] gi|119947691|gb|ABM06602.1| GDP-mannose 4,6-dehydratase [Arthrobacter aurescens TC1] Length=345 Score = 541 bits (1395), Expect = 4e-152, Method: Compositional matrix adjust. Identities = 263/331 (80%), Positives = 293/331 (89%), Gaps = 0/331 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K+ALITGITGQDGSYLAELLL+KGYEVHGLIRR+STFNTSRIDHLYVDPH ARLFLHY Sbjct 3 KKALITGITGQDGSYLAELLLSKGYEVHGLIRRSSTFNTSRIDHLYVDPHNSEARLFLHY 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL DGTRLVTLL+ I PDEVYNL AQSHVRVSFDEP HTG+TTG+G+ RLLEAVR++ + Sbjct 63 GDLSDGTRLVTLLAEIRPDEVYNLGAQSHVRVSFDEPEHTGNTTGIGTTRLLEAVRMAGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 RFYQASSSEMFGA+PPPQ+E TPFYPRSPYGAAKVYSYW T+NYREAYG+FAVNGILF Sbjct 123 ETRFYQASSSEMFGATPPPQDEATPFYPRSPYGAAKVYSYWMTKNYREAYGMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVA IKAG QSE+YMGNL AVRDWGYA EYVEGMWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVAAIKAGKQSELYMGNLQAVRDWGYAAEYVEGMWRMLQVDE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+VLAT G+TV++F AFEH GL+W+ YV+FD+RYLRPTEV++LIGD +KA E L Sbjct 243 PDDYVLATNEGYTVKDFLENAFEHVGLNWENYVRFDERYLRPTEVEALIGDYSKAKEKLD 302 Query 302 WRASVHTDELARIMVDADMAALECEGKPWID 332 W +V T ELAR+MVDAD+ AL+ G PWID Sbjct 303 WEPTVKTPELARLMVDADIKALQHGGNPWID 333 >gi|284030676|ref|YP_003380607.1| GDP-mannose 4,6-dehydratase [Kribbella flavida DSM 17836] gi|283809969|gb|ADB31808.1| GDP-mannose 4,6-dehydratase [Kribbella flavida DSM 17836] Length=327 Score = 525 bits (1353), Expect = 3e-147, Method: Compositional matrix adjust. Identities = 256/326 (79%), Positives = 290/326 (89%), Gaps = 0/326 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+A +TGITGQDGSYLAELLLAKGYEVHGLIRRASTFNT RIDHLY DPH+P RLFLH Sbjct 1 MKKAFVTGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTRRIDHLYTDPHEPDKRLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL DG+RLVTLL+ I+P+EVY+LAAQSHVRVSFDEP +TGDTTGMG+ RLLEA+R+ Sbjct 61 YGDLTDGSRLVTLLAAIQPEEVYHLAAQSHVRVSFDEPEYTGDTTGMGTTRLLEAIRMIG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 ++CRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVY YW TRNYREAY LFAVNGIL Sbjct 121 LNCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYGYWMTRNYREAYDLFAVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRAVARIK G++ VY+GNLDA RDWGYAPEYVEGMWRMLQ Sbjct 181 FNHESPRRGETFVTRKITRAVARIKLGLEKRVYLGNLDARRDWGYAPEYVEGMWRMLQHH 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 +PDD+V+ATG ++VR+F AF+HAGLDW+++V +DQRY RPTEVDSL+GDA+KA L Sbjct 241 QPDDYVVATGTSYSVRDFVSLAFQHAGLDWEEHVDYDQRYERPTEVDSLVGDASKAQVEL 300 Query 301 GWRASVHTDELARIMVDADMAALECE 326 GW+A VH +L RIMVDAD+AAL E Sbjct 301 GWKAEVHVPDLVRIMVDADLAALTEE 326 >gi|117927658|ref|YP_872209.1| GDP-mannose 4,6-dehydratase [Acidothermus cellulolyticus 11B] gi|117648121|gb|ABK52223.1| GDP-mannose 4,6-dehydratase [Acidothermus cellulolyticus 11B] Length=380 Score = 516 bits (1330), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 250/339 (74%), Positives = 283/339 (84%), Gaps = 9/339 (2%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 +RALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNT RIDH+Y DPH P RL LHY Sbjct 46 RRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTERIDHIYQDPHDPDVRLRLHY 105 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL DGT LVTLL TIEPDEVY+L AQSHV+VSF P +TGD TG+G++RLLEA+R S + Sbjct 106 GDLHDGTGLVTLLHTIEPDEVYHLGAQSHVKVSFAMPEYTGDVTGLGTIRLLEAIRASGI 165 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 CRFYQASSSEMFG++PPPQNE TPF+PRSPYG AKVY+YWAT NYREAYGLFAVNGILF Sbjct 166 SCRFYQASSSEMFGSAPPPQNEKTPFHPRSPYGVAKVYAYWATVNYREAYGLFAVNGILF 225 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRK++RAVARI+AG+Q ++Y+GNLDA RDWGYAPEYVE MW MLQ DE Sbjct 226 NHESPRRGETFVTRKVSRAVARIQAGLQDKLYLGNLDARRDWGYAPEYVEAMWLMLQADE 285 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P D+V+ATG + VR+F AF+HAGLDW++YV+ D+RY RP EVD L GDA+KA LG Sbjct 286 PADYVIATGTSYAVRDFVAMAFDHAGLDWEKYVEIDERYRRPAEVDHLCGDASKAKAELG 345 Query 302 WRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT 340 W A V T ELARIMVDAD+A L E +AGRT Sbjct 346 WEARVKTPELARIMVDADIARLGDE---------LAGRT 375 >gi|239991460|ref|ZP_04712124.1| putative GDP-D-mannose dehydratase [Streptomyces roseosporus NRRL 11379] gi|291448456|ref|ZP_06587846.1| GDP-mannose 4,6-dehydratase [Streptomyces roseosporus NRRL 15998] gi|291351403|gb|EFE78307.1| GDP-mannose 4,6-dehydratase [Streptomyces roseosporus NRRL 15998] Length=351 Score = 499 bits (1285), Expect = 3e-139, Method: Compositional matrix adjust. Identities = 235/322 (73%), Positives = 270/322 (84%), Gaps = 0/322 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYLAELLL KGY VHGLIRR+S+FNT RIDH+Y P +P LH+ Sbjct 17 KTALITGVTGQDGSYLAELLLDKGYTVHGLIRRSSSFNTERIDHIYQGPEEPERSFVLHH 76 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I+PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEAVR S + Sbjct 77 ADLSDGVALVNLLRDIQPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGTIRLLEAVRASGI 136 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGASPPPQNE TPF+PRSPY AKVYSYWAT NYREAY +FAVNGILF Sbjct 137 QTRIYQASSSEMFGASPPPQNEKTPFHPRSPYSVAKVYSYWATVNYREAYDMFAVNGILF 196 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITR VARIKAG+Q +++GNLDAVRDWGYAPEYV+ MWRMLQ D Sbjct 197 NHESPRRGETFVTRKITRGVARIKAGLQDRLHLGNLDAVRDWGYAPEYVDAMWRMLQCDT 256 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDDFV+ATG G +VR+F AFEHAGLDW+++V++D +Y RP+EVD+LIGDA+KA ELLG Sbjct 257 PDDFVIATGEGVSVRDFLEYAFEHAGLDWREHVRYDPKYERPSEVDALIGDASKAEELLG 316 Query 302 WRASVHTDELARIMVDADMAAL 323 W+ V + ELARIMVDAD+ L Sbjct 317 WKPEVKSRELARIMVDADIRRL 338 >gi|302523155|ref|ZP_07275497.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SPB78] gi|302432050|gb|EFL03866.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SPB78] Length=337 Score = 499 bits (1284), Expect = 3e-139, Method: Compositional matrix adjust. Identities = 238/323 (74%), Positives = 273/323 (85%), Gaps = 0/323 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITGITGQDGSYLAELLLAKGYEVHGL+RR+S+FNT RIDH+Y P + RL LH+ Sbjct 3 KTALITGITGQDGSYLAELLLAKGYEVHGLLRRSSSFNTERIDHIYQGPQENDRRLVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEA+R S V Sbjct 63 ADLGDGVALVNLLREIGPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGALRLLEAIRASGV 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFG++PPPQNE TPF+PRSPYGAAKV++YWAT NYREAY +FAVNGILF Sbjct 123 DTRIYQASSSEMFGSTPPPQNEGTPFHPRSPYGAAKVFAYWATVNYREAYDMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVARIKAG+Q +Y+GNLDAVRDWGYAPEYVE MWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVARIKAGLQEHLYLGNLDAVRDWGYAPEYVEAMWRMLQHDE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P D+V+ATG TVR+F AF HAGLDW +V++D +Y RP+EVD+LIGDA+KA ELLG Sbjct 243 PTDYVVATGVPATVRQFTETAFAHAGLDWNAHVRYDAKYERPSEVDALIGDASKARELLG 302 Query 302 WRASVHTDELARIMVDADMAALE 324 W+ SV +ELARIMVDAD+ +E Sbjct 303 WKPSVLVEELARIMVDADVRQVE 325 >gi|318057299|ref|ZP_07976022.1| putative GDP-D-mannose dehydratase [Streptomyces sp. SA3_actG] gi|318076223|ref|ZP_07983555.1| putative GDP-D-mannose dehydratase [Streptomyces sp. SA3_actF] Length=337 Score = 499 bits (1284), Expect = 4e-139, Method: Compositional matrix adjust. Identities = 238/323 (74%), Positives = 273/323 (85%), Gaps = 0/323 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITGITGQDGSYLAELLLAKGYEVHGL+RR+S+FNT RIDH+Y P + RL LH+ Sbjct 3 KTALITGITGQDGSYLAELLLAKGYEVHGLLRRSSSFNTERIDHIYQGPQEDDRRLVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEA+R S V Sbjct 63 ADLGDGVALVNLLREIGPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGALRLLEAIRASGV 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFG++PPPQNE TPF+PRSPYGAAKV++YWAT NYREAY +FAVNGILF Sbjct 123 DTRIYQASSSEMFGSTPPPQNEGTPFHPRSPYGAAKVFAYWATVNYREAYDMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVARIKAG+Q +Y+GNLDAVRDWGYAPEYVE MWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVARIKAGLQEHLYLGNLDAVRDWGYAPEYVEAMWRMLQHDE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P D+V+ATG TVR+F AF HAGLDW +V++D +Y RP+EVD+LIGDA+KA ELLG Sbjct 243 PTDYVVATGVPATVRQFTETAFAHAGLDWNAHVRYDAKYERPSEVDALIGDASKARELLG 302 Query 302 WRASVHTDELARIMVDADMAALE 324 W+ SV +ELARIMVDAD+ +E Sbjct 303 WKPSVLVEELARIMVDADVRQVE 325 >gi|326775975|ref|ZP_08235240.1| GDP-mannose 4,6-dehydratase [Streptomyces cf. griseus XylebKG-1] gi|326656308|gb|EGE41154.1| GDP-mannose 4,6-dehydratase [Streptomyces griseus XylebKG-1] Length=353 Score = 495 bits (1274), Expect = 4e-138, Method: Compositional matrix adjust. Identities = 232/323 (72%), Positives = 271/323 (84%), Gaps = 0/323 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYLAELLL KGY VHGLIRR+S+FNT RIDH+Y P +P LH+ Sbjct 19 KTALITGVTGQDGSYLAELLLDKGYTVHGLIRRSSSFNTERIDHIYQGPEEPERSFVLHH 78 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I+PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEAVR S + Sbjct 79 ADLSDGVALVNLLRDIQPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGTIRLLEAVRASGI 138 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGASPPPQNE T F+PRSPY AKVY+YWAT NYREAYG+FAVNGILF Sbjct 139 ETRIYQASSSEMFGASPPPQNEDTSFHPRSPYSVAKVYAYWATVNYREAYGMFAVNGILF 198 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITR VARIKAG+Q +++GNLDAVRDWGYAPEYV+ MWRMLQ D Sbjct 199 NHESPRRGETFVTRKITRGVARIKAGLQDRLHLGNLDAVRDWGYAPEYVDAMWRMLQCDT 258 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+V+ATG G +VR+F AFEHAGLDW+++V++D +Y RP+EVD+LIGDA+KA +LLG Sbjct 259 PDDYVVATGEGVSVRQFVEFAFEHAGLDWREHVRYDPKYERPSEVDALIGDASKAEQLLG 318 Query 302 WRASVHTDELARIMVDADMAALE 324 W+ V + ELARIMVDAD+ L+ Sbjct 319 WKPEVRSRELARIMVDADIRRLD 341 >gi|182435335|ref|YP_001823054.1| putative GDP-D-mannose dehydratase [Streptomyces griseus subsp. griseus NBRC 13350] gi|178463851|dbj|BAG18371.1| putative GDP-D-mannose dehydratase [Streptomyces griseus subsp. griseus NBRC 13350] Length=337 Score = 494 bits (1273), Expect = 7e-138, Method: Compositional matrix adjust. Identities = 232/323 (72%), Positives = 271/323 (84%), Gaps = 0/323 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYLAELLL KGY VHGLIRR+S+FNT RIDH+Y P +P LH+ Sbjct 3 KTALITGVTGQDGSYLAELLLDKGYTVHGLIRRSSSFNTERIDHIYQGPEEPERSFVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I+PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEAVR S + Sbjct 63 ADLSDGVALVNLLRDIQPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGTIRLLEAVRASGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGASPPPQNE T F+PRSPY AKVY+YWAT NYREAYG+FAVNGILF Sbjct 123 ETRIYQASSSEMFGASPPPQNEDTSFHPRSPYSVAKVYAYWATVNYREAYGMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITR VARIKAG+Q +++GNLDAVRDWGYAPEYV+ MWRMLQ D Sbjct 183 NHESPRRGETFVTRKITRGVARIKAGLQDRLHLGNLDAVRDWGYAPEYVDAMWRMLQCDT 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+V+ATG G +VR+F AFEHAGLDW+++V++D +Y RP+EVD+LIGDA+KA +LLG Sbjct 243 PDDYVVATGEGVSVRQFVEFAFEHAGLDWREHVRYDPKYERPSEVDALIGDASKAEQLLG 302 Query 302 WRASVHTDELARIMVDADMAALE 324 W+ V + ELARIMVDAD+ L+ Sbjct 303 WKPEVRSRELARIMVDADIRRLD 325 >gi|320007946|gb|ADW02796.1| GDP-mannose 4,6-dehydratase [Streptomyces flavogriseus ATCC 33331] Length=337 Score = 494 bits (1272), Expect = 8e-138, Method: Compositional matrix adjust. Identities = 232/322 (73%), Positives = 268/322 (84%), Gaps = 0/322 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYL+ELLL KGY VHGLIRR+S+FNT RIDH+Y P + LH+ Sbjct 3 KTALITGVTGQDGSYLSELLLEKGYTVHGLIRRSSSFNTERIDHIYQGPEEANRSFVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I+PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEAVR S + Sbjct 63 ADLSDGVALVNLLRDIQPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGTVRLLEAVRASGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGASPPPQNE TPF+PRSPY AKVYSYWAT NYREAYG+FA NGILF Sbjct 123 ETRVYQASSSEMFGASPPPQNEKTPFHPRSPYSVAKVYSYWATVNYREAYGMFATNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITR VARIKAG+Q +++GNLDAVRDWGYAPEYVE MWRMLQ + Sbjct 183 NHESPRRGETFVTRKITRGVARIKAGLQDRLHLGNLDAVRDWGYAPEYVEAMWRMLQCET 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+V+ATG G +VR+F AFEHAGLDW ++V++D +Y RP+EVD+LIGDA+KA ELLG Sbjct 243 PDDYVVATGEGVSVRQFLEYAFEHAGLDWAEHVRYDPKYERPSEVDALIGDASKAEELLG 302 Query 302 WRASVHTDELARIMVDADMAAL 323 W+ V + ELARIMVDAD+ L Sbjct 303 WKPEVKSRELARIMVDADIRLL 324 >gi|254382404|ref|ZP_04997764.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. Mg1] gi|194341309|gb|EDX22275.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. Mg1] Length=337 Score = 493 bits (1268), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 230/325 (71%), Positives = 271/325 (84%), Gaps = 0/325 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYLAELLL+KGY VHGL+RR+S+FNT RIDH+Y DP LH+ Sbjct 3 KTALITGVTGQDGSYLAELLLSKGYTVHGLVRRSSSFNTERIDHIYQDPQTANRSFVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEA+R S V Sbjct 63 ADLADGVALVNLLREIRPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGALRLLEAIRASGV 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGA+PPPQNE TPF+PRSPYGAAKV++YW T NYREAY +FAVNGILF Sbjct 123 DTRIYQASSSEMFGATPPPQNEGTPFHPRSPYGAAKVFAYWTTVNYREAYDMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVARIKAG+Q +Y+GNLDAVRDWGYAPEYV+ MWRMLQ DE Sbjct 183 NHESPRRGETFVTRKITRAVARIKAGLQDHLYLGNLDAVRDWGYAPEYVDAMWRMLQQDE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P D+V+ATG TVREF A+F HAGLDW ++V++D +Y RP+EVD+LIGDA+KA ++LG Sbjct 243 PTDYVVATGVAATVREFVEASFGHAGLDWNEHVRYDPKYERPSEVDALIGDASKAQDILG 302 Query 302 WRASVHTDELARIMVDADMAALECE 326 W+ +V ELA+IMVDAD+ +E + Sbjct 303 WKPTVLVSELAQIMVDADVRQVEDQ 327 >gi|345002640|ref|YP_004805494.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SirexAA-E] gi|344318266|gb|AEN12954.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. SirexAA-E] Length=337 Score = 488 bits (1256), Expect = 6e-136, Method: Compositional matrix adjust. Identities = 228/322 (71%), Positives = 267/322 (83%), Gaps = 0/322 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYL+ELLL KGY VHGLIRR+S+FNT RIDH+Y P + LH+ Sbjct 3 KTALITGVTGQDGSYLSELLLDKGYTVHGLIRRSSSFNTERIDHIYQGPEEANRSFVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEAVR S V Sbjct 63 ADLSDGVALVNLLRDIRPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGTIRLLEAVRASGV 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFGASPPPQ+E TPF+PRSPY AKVY+YWAT NYREAYG++AVNGILF Sbjct 123 ETRIYQASSSEMFGASPPPQDERTPFHPRSPYSVAKVYAYWATVNYREAYGMYAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRK+TR +ARIKAG+Q +++GNLDAVRDWGYAPEYV+ MWRMLQ D Sbjct 183 NHESPRRGETFVTRKVTRGIARIKAGLQDRLHLGNLDAVRDWGYAPEYVDAMWRMLQCDA 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+V+ATG G +VR+F AF HAGLDW ++V++D +Y RP+EVD+L+GDA+KA ELLG Sbjct 243 PDDYVVATGEGVSVRQFVEYAFAHAGLDWAEHVRYDPKYERPSEVDALVGDASKAGELLG 302 Query 302 WRASVHTDELARIMVDADMAAL 323 W+ V T ELARIMVDAD+ L Sbjct 303 WKPEVKTRELARIMVDADIRLL 324 >gi|119718422|ref|YP_925387.1| GDP-mannose 4,6-dehydratase [Nocardioides sp. JS614] gi|119539083|gb|ABL83700.1| GDP-mannose 4,6-dehydratase [Nocardioides sp. JS614] Length=340 Score = 488 bits (1255), Expect = 8e-136, Method: Compositional matrix adjust. Identities = 228/333 (69%), Positives = 272/333 (82%), Gaps = 0/333 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITGITGQDGSYLAELLLAKGY VHGL RR+STFN+SRI+HLY DPH P RLFLHY Sbjct 3 KTALITGITGQDGSYLAELLLAKGYVVHGLRRRSSTFNSSRIEHLYQDPHDPDTRLFLHY 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL D L+ LL I+PDEVYNLA QSHV SFDEP HT TTG+G + LLEA+R + Sbjct 63 ADLTDAANLIRLLHRIQPDEVYNLAGQSHVGASFDEPEHTAITTGVGPLTLLEAIRTVGI 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 CRFYQASSS M+GA+ Q+E +PF P SPYGAAK+++YW+T YRE YG+FAV+GILF Sbjct 123 DCRFYQASSSAMYGAATGAQDECSPFRPLSPYGAAKLHAYWSTVTYREGYGMFAVSGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETF+TRK+TRAVARI+AG+ +Y+GNL+ RDWGYAPEYVEGMWRMLQ DE Sbjct 183 NHESPRRGETFLTRKVTRAVARIQAGLDDFLYLGNLEPTRDWGYAPEYVEGMWRMLQADE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+VLATG ++VR+F AAFEHAGLDW+++V+ D+RY+RP E SL+GDA+KA LG Sbjct 243 PDDYVLATGTSYSVRDFVVAAFEHAGLDWEKHVRRDERYVRPNENPSLVGDASKAEARLG 302 Query 302 WRASVHTDELARIMVDADMAALECEGKPWIDKP 334 W+A V+ DEL R+MVDAD+ A+ EG+PWID P Sbjct 303 WKAHVNADELVRLMVDADVQAVASEGRPWIDTP 335 >gi|302537023|ref|ZP_07289365.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. C] gi|302445918|gb|EFL17734.1| GDP-mannose 4,6-dehydratase [Streptomyces sp. C] Length=361 Score = 487 bits (1254), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 227/325 (70%), Positives = 269/325 (83%), Gaps = 0/325 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITG+TGQDGSYLAELLL+KGY VHGL+RR+S+FNT RIDH+Y DP LH+ Sbjct 27 KTALITGVTGQDGSYLAELLLSKGYTVHGLVRRSSSFNTERIDHIYQDPQTANRSFVLHH 86 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV LL I PDEVYNL AQSHVRVSFD P++TGD TG+G++RLLEA+R S V Sbjct 87 ADLSDGVALVNLLRDIRPDEVYNLGAQSHVRVSFDAPLYTGDVTGLGALRLLEAIRASGV 146 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEM+G++PPPQNE TPF+PRSPYG AKV++YW T NYREAYG+FAVNGILF Sbjct 147 DTRIYQASSSEMYGSTPPPQNEDTPFHPRSPYGGAKVFAYWTTVNYREAYGMFAVNGILF 206 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVARIKAG+Q +Y+GNLDAVRDWGYAPEYV+ MWRMLQ DE Sbjct 207 NHESPRRGETFVTRKITRAVARIKAGLQDHLYLGNLDAVRDWGYAPEYVDAMWRMLQQDE 266 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 P D+V+ATG TVR+F ++F HAGLDW +V++D +Y RP+EVD+LIGDA+KA E+LG Sbjct 267 PSDYVVATGVAATVRDFVESSFAHAGLDWTDHVRYDPKYERPSEVDALIGDASKAREILG 326 Query 302 WRASVHTDELARIMVDADMAALECE 326 W+ V ELA+IMVDAD+ +E + Sbjct 327 WKPMVLAPELAQIMVDADVRQVEDQ 351 >gi|83744452|gb|ABC42542.1| putative mannose dehydratase [Streptomyces hygroscopicus] Length=352 Score = 487 bits (1254), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 241/341 (71%), Positives = 281/341 (83%), Gaps = 1/341 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +KRALITGITGQDGSYLA+LLL KGYEVHG++RR+STFNT R+DH+Y DPH G RL LH Sbjct 1 MKRALITGITGQDGSYLADLLLDKGYEVHGIVRRSSTFNTRRLDHIYRDPHDAGRRLILH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGD+ D +RLVTLL+ + PDEVY+LAAQSHVRVSFDEP +TGD TGMG+ RLLEA+R+S Sbjct 61 YGDVSDASRLVTLLARVRPDEVYHLAAQSHVRVSFDEPENTGDITGMGTTRLLEAIRMSA 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + R+YQASSSEMFGA+PPPQNE T F+PRSPYGAAKVYSYW TRNYREAYG+F VNGIL Sbjct 121 MDIRYYQASSSEMFGAAPPPQNERTTFHPRSPYGAAKVYSYWMTRNYREAYGMFTVNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKI RA ARIKAG + V++GNLDAVRDWGYAPEYVEGMWRM+Q D Sbjct 181 FNHESPRRGETFVTRKIARAAARIKAGFEKHVFLGNLDAVRDWGYAPEYVEGMWRMMQLD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL 300 +PDD+VLATG G TVREFA F H GLDW+++V++D YLRP EVD+L+GDA KA E Sbjct 241 QPDDYVLATGIGSTVREFAEHCFSHVGLDWREHVRYDDVYLRPAEVDTLVGDAGKAREAF 300 Query 301 GWRASVHTDELARIMVDADMAALECEGK-PWIDKPMIAGRT 340 GW A LA+IMVDA++A L + + W P + RT Sbjct 301 GWTARTSVYRLAQIMVDAELARLGSDSRETWSANPFTSART 341 >gi|152965793|ref|YP_001361577.1| GDP-mannose 4,6-dehydratase [Kineococcus radiotolerans SRS30216] gi|151360310|gb|ABS03313.1| GDP-mannose 4,6-dehydratase [Kineococcus radiotolerans SRS30216] Length=330 Score = 475 bits (1223), Expect = 4e-132, Method: Compositional matrix adjust. Identities = 241/322 (75%), Positives = 271/322 (85%), Gaps = 0/322 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K ALITGITGQDGSYLAELLL KGYEVHGLIRR+S+FNT+RIDHLY DPH P AR FLHY Sbjct 3 KTALITGITGQDGSYLAELLLEKGYEVHGLIRRSSSFNTTRIDHLYQDPHDPHARFFLHY 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 GDL DG+R+VTLL I PDEVY+LAAQSHVRVSFDEP TGDTTG+G+ R+LEA+R+ + Sbjct 63 GDLTDGSRMVTLLDDIRPDEVYHLAAQSHVRVSFDEPEFTGDTTGLGTTRILEAIRMIGL 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 CRFYQASSSEMFGA+PPPQ+E TPF+PRSPYGAAKVY YW TRNYREAYG+FAVNGILF Sbjct 123 QCRFYQASSSEMFGATPPPQSETTPFHPRSPYGAAKVYGYWMTRNYREAYGMFAVNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKI A ARI AG Q +Y+GNLDAVRDWGYA EYVEGMWRMLQ DE Sbjct 183 NHESPRRGETFVTRKIAAAAARIAAGKQETLYLGNLDAVRDWGYAKEYVEGMWRMLQQDE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 D+VLATG G TVREF + FE GLDW+ +V D+RY+RP EVD+LIGDA+KA LG Sbjct 243 ASDYVLATGVGTTVREFTQDCFESVGLDWRDHVAHDERYVRPAEVDALIGDASKARRELG 302 Query 302 WRASVHTDELARIMVDADMAAL 323 W A+V ELAR+M +A+ AL Sbjct 303 WTATVQASELARLMTEAERRAL 324 >gi|196230860|ref|ZP_03129721.1| GDP-mannose 4,6-dehydratase [Chthoniobacter flavus Ellin428] gi|196225201|gb|EDY19710.1| GDP-mannose 4,6-dehydratase [Chthoniobacter flavus Ellin428] Length=325 Score = 469 bits (1206), Expect = 4e-130, Method: Compositional matrix adjust. Identities = 224/325 (69%), Positives = 258/325 (80%), Gaps = 1/325 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+ALITGITGQDGSYLA+LLL KGYEVHG+IRRASTFNTSRIDHLY DPH G RLFLH Sbjct 1 MKKALITGITGQDGSYLADLLLEKGYEVHGIIRRASTFNTSRIDHLYADPHVHGVRLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL D L L+ + P+E+Y+L AQSHVRVSFD P +TGD T +G++R+LEA+R S+ Sbjct 61 YGDLSDALNLTRLIDRVGPEEIYHLGAQSHVRVSFDIPENTGDVTALGTIRILEAIRESK 120 Query 121 VHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGI 179 V RFYQASSSEMFG PQ E TPF+PRSPY AKVY+YWAT NYRE+YG+ A NGI Sbjct 121 VQARFYQASSSEMFGKVQAVPQTETTPFWPRSPYAVAKVYAYWATVNYRESYGMHASNGI 180 Query 180 LFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQT 239 LFNHESPRRGETFVTRKITRAVA IK G Q E+Y+GNLDA RDWG+APEYVEGMWRMLQ Sbjct 181 LFNHESPRRGETFVTRKITRAVAAIKKGKQKELYLGNLDAKRDWGFAPEYVEGMWRMLQQ 240 Query 240 DEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAEL 299 E DD+VLAT +V+EF AF H GLDW++YVK+D RY RP EV+ LIGD KA Sbjct 241 PEGDDYVLATNETHSVKEFVVEAFGHVGLDWEKYVKYDARYERPAEVELLIGDPAKAKTK 300 Query 300 LGWRASVHTDELARIMVDADMAALE 324 LGW H +L +IMVDAD+AAL+ Sbjct 301 LGWEPKTHFKDLVKIMVDADLAALD 325 >gi|312194091|ref|YP_004014152.1| GDP-mannose 4,6-dehydratase [Frankia sp. EuI1c] gi|311225427|gb|ADP78282.1| GDP-mannose 4,6-dehydratase [Frankia sp. EuI1c] Length=337 Score = 468 bits (1205), Expect = 5e-130, Method: Compositional matrix adjust. Identities = 214/325 (66%), Positives = 263/325 (81%), Gaps = 0/325 (0%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 K AL+TG+TGQDGSYL ELLL KGYEVHGL+RR+S+FNT+RIDHLY DPH+ G +L LH+ Sbjct 3 KVALVTGVTGQDGSYLCELLLQKGYEVHGLVRRSSSFNTARIDHLYQDPHEDGRKLVLHH 62 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSRV 121 DL DG LV +L P EVYNL AQSHVRVS+D P++T + TG+G++R+LEAVR S + Sbjct 63 ADLDDGLSLVNILRETGPSEVYNLGAQSHVRVSYDTPLYTANVTGVGALRILEAVRASNL 122 Query 122 HCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGILF 181 R YQASSSEMFG++PPPQNE TPF+PRSPY AKVY+YW+ N+RE+YG++ NGILF Sbjct 123 DIRVYQASSSEMFGSTPPPQNEETPFHPRSPYACAKVYAYWSAVNHRESYGMYVSNGILF 182 Query 182 NHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTDE 241 NHESPRRGETFVTRKITRAVARI+AG+Q E+Y+GNLDA RDWGYAPEYV MW MLQ E Sbjct 183 NHESPRRGETFVTRKITRAVARIQAGLQKELYLGNLDATRDWGYAPEYVNAMWMMLQAPE 242 Query 242 PDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELLG 301 PDD+V+ATG ++VREF + AF H GL+W+ YV+FD +Y RP EVD+L+GDA+K LG Sbjct 243 PDDYVVATGTTYSVREFCQVAFGHVGLNWEDYVRFDPKYTRPAEVDALMGDASKIRTNLG 302 Query 302 WRASVHTDELARIMVDADMAALECE 326 W+ V+ +EL +IMVD D+ LE E Sbjct 303 WKPEVNFEELVQIMVDGDIQLLEDE 327 >gi|4097914|gb|AAD10232.1| putative GDP-D-mannose dehydratase [Anabaena sp. CA] Length=359 Score = 467 bits (1201), Expect = 1e-129, Method: Compositional matrix adjust. Identities = 223/327 (69%), Positives = 257/327 (79%), Gaps = 5/327 (1%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYL+E LL +GYEVHG+IRR STFNT RIDH+Y DPH+ G RLFLHY Sbjct 5 KRALITGITGQDGSYLSEFLLGQGYEVHGIIRRTSTFNTDRIDHIYEDPHKEGVRLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR---- 117 GDL DGT L +L ++P E+YNL AQSHVRVSFD P +T D+ GMG++RLLEA+R Sbjct 65 GDLTDGTTLRRILEEVQPTEIYNLGAQSHVRVSFDSPEYTVDSVGMGTLRLLEAIRDYQH 124 Query 118 LSRVHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 + + RFYQA SSEM+G PQ+E TPFYPRSPY AKVY++W T NYRE+YGLFA Sbjct 125 RTGIQVRFYQAGSSEMYGLVQAVPQSETTPFYPRSPYACAKVYAHWQTVNYRESYGLFAC 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRAVARI AG Q +YMGNLDA RDWGYA +YV MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRAVARIVAGKQKTLYMGNLDAKRDWGYAKDYVRAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ D+PDD+V+ATG +VREF AF H LDWQ YV+FD+RYLRP EVD LIGD+TKA Sbjct 245 LQQDQPDDYVIATGETHSVREFLELAFSHVNLDWQDYVEFDERYLRPAEVDLLIGDSTKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAAL 323 + LGWR SV EL +MVDAD+ A+ Sbjct 305 QQKLGWRPSVTFKELVALMVDADLQAI 331 >gi|320160406|ref|YP_004173630.1| GDP-mannose 4,6-dehydratase [Anaerolinea thermophila UNI-1] gi|319994259|dbj|BAJ63030.1| GDP-mannose 4,6-dehydratase [Anaerolinea thermophila UNI-1] Length=377 Score = 466 bits (1199), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 226/332 (69%), Positives = 259/332 (79%), Gaps = 4/332 (1%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPG--ARLF 58 +K+ALITGITGQDGSYLAELLL+KGYEVHG+IRRASTFNT RIDH+Y DPH G L+ Sbjct 21 LKKALITGITGQDGSYLAELLLSKGYEVHGMIRRASTFNTRRIDHIYRDPHANGDPVHLY 80 Query 59 LHYGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRL 118 LHYGDL L+ ++ I PDE+Y+L AQSHVRVSFD P TGD TG+G+ R+LEA+R Sbjct 81 LHYGDLTASDTLLDIIYNIRPDEIYHLGAQSHVRVSFDMPEFTGDVTGLGTARILEAIRK 140 Query 119 SRVHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNG 178 S V RFYQASSSEMFG++ PPQNE TPF PRSPY AK+YSYW TRNYREAY +FAVNG Sbjct 141 SGVKARFYQASSSEMFGSAKPPQNEQTPFEPRSPYAVAKLYSYWLTRNYREAYNIFAVNG 200 Query 179 ILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQ 238 ILFNHESPRRGETFVTRKITRA+A I+AG Q +Y+GNLD+ RDWGYAPEYVE MW ML Sbjct 201 ILFNHESPRRGETFVTRKITRALASIRAGKQKVLYLGNLDSKRDWGYAPEYVEAMWMMLN 260 Query 239 TDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAE 298 DEPDDFV+ TG TVREF AF + +DW +YVK D RY RPTEVD L+ DA+KA Sbjct 261 RDEPDDFVIGTGEAHTVREFLDEAFGYLDMDWHEYVKIDPRYFRPTEVDYLLADASKARR 320 Query 299 LLGWRASVHTDELARIMVDAD--MAALECEGK 328 +LGW V EL RIMVDAD + LEC G+ Sbjct 321 VLGWEPKVRFRELVRIMVDADLELMGLECPGE 352 >gi|218440329|ref|YP_002378658.1| GDP-mannose 4,6-dehydratase [Cyanothece sp. PCC 7424] gi|218173057|gb|ACK71790.1| GDP-mannose 4,6-dehydratase [Cyanothece sp. PCC 7424] Length=360 Score = 465 bits (1197), Expect = 4e-129, Method: Compositional matrix adjust. Identities = 225/336 (67%), Positives = 262/336 (78%), Gaps = 8/336 (2%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYL+ELLL KGYEVHG+IRR STFNT RIDHLYVDPH ARLFLHY Sbjct 5 KRALITGITGQDGSYLSELLLEKGYEVHGIIRRTSTFNTDRIDHLYVDPHNTEARLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR---- 117 GDL DGT L +L ++P E+YNL AQSHVRVSFD P +T D+ GMG++R+LEA+R Sbjct 65 GDLTDGTTLRRILEQVQPIEIYNLGAQSHVRVSFDSPEYTVDSVGMGTLRILEAIRDYQH 124 Query 118 LSRVHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 + + RFYQA SSEMFG PQ E TPFYPRSPY AKVY+YW T NYRE+Y +FA Sbjct 125 RTGIKVRFYQAGSSEMFGKVQEIPQKETTPFYPRSPYACAKVYAYWQTLNYRESYEIFAC 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRA+ARI A Q ++Y+GNLDA RDWGYA +YV+ MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRAIARIVAEQQKKLYLGNLDAQRDWGYAKDYVQAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ DEPDD+V+ATG +V+EF AF+ LDWQ+YV+FDQRYLRP EVD LIGD TKA Sbjct 245 LQQDEPDDYVVATGETHSVKEFLEIAFKVVNLDWQKYVEFDQRYLRPAEVDLLIGDPTKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAAL---ECEGKP 329 + LGW+ SV ++L +MV+AD+AAL GKP Sbjct 305 KKKLGWQPSVTFEQLVHLMVEADLAALGISMSNGKP 340 >gi|159027653|emb|CAO89517.1| unnamed protein product [Microcystis aeruginosa PCC 7806] Length=360 Score = 461 bits (1187), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 220/327 (68%), Positives = 259/327 (80%), Gaps = 5/327 (1%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYL+ELLL KGYEVHG+IRR STFNT RIDH+Y+DPHQP A+LFLHY Sbjct 5 KRALITGITGQDGSYLSELLLEKGYEVHGIIRRTSTFNTDRIDHIYIDPHQPDAKLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR---- 117 GDL DGT L +L ++P EVYNL AQSHVRVSFD P +T D G+G +RLLEA+R Sbjct 65 GDLTDGTTLRRILEQVQPVEVYNLGAQSHVRVSFDAPEYTVDAVGVGVLRLLEAIRDYQK 124 Query 118 LSRVHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 + + RFYQA SSEMFG PQ E TPFYPRSPY AKVY +W T NYRE+Y LFA Sbjct 125 RTGIEVRFYQAGSSEMFGKVMEVPQKETTPFYPRSPYACAKVYGHWQTINYRESYDLFAC 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRA+ARI AG Q ++Y+GNLD+ RDWGYA +YV MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRALARIIAGQQKKLYLGNLDSKRDWGYAKDYVRAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ +EPDD+V+AT +++REF +F++ L+WQ YV+FDQRYLRP EVD LIGD+TKA Sbjct 245 LQQEEPDDYVVATNETYSIREFLDISFQYVNLNWQDYVEFDQRYLRPAEVDLLIGDSTKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAAL 323 E LGW+ SV + L ++MVDAD+AAL Sbjct 305 REKLGWQPSVTFEGLVKLMVDADLAAL 331 >gi|334117521|ref|ZP_08491612.1| GDP-mannose 4,6-dehydratase [Microcoleus vaginatus FGP-2] gi|333460630|gb|EGK89238.1| GDP-mannose 4,6-dehydratase [Microcoleus vaginatus FGP-2] Length=343 Score = 461 bits (1187), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 218/332 (66%), Positives = 260/332 (79%), Gaps = 5/332 (1%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYL+ELLL KGYEVHG+IRR+S+FNT RIDH+YVDPH GARLFLHY Sbjct 5 KRALITGITGQDGSYLSELLLEKGYEVHGIIRRSSSFNTDRIDHIYVDPHSEGARLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR---- 117 GDL DGT L +L ++P E+YNL AQSHVRVSFD P +T D GMG +RLLEA+R Sbjct 65 GDLTDGTTLRRILEEVQPVEIYNLGAQSHVRVSFDSPEYTVDAVGMGVLRLLEAIRDYQR 124 Query 118 LSRVHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 + + RFYQA SSEMFG PQ E TPFYPRSPY AKVY +W T NYRE+YGLFA Sbjct 125 RTGIEVRFYQAGSSEMFGLVQEVPQKETTPFYPRSPYACAKVYGHWQTVNYRESYGLFAC 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRA+ARI AG Q ++++GNLD+ RDWGYA +YV+ MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRAIARILAGKQKKIFLGNLDSKRDWGYAKDYVQAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ ++PDD+V+AT +++EF AF + LDWQ+YV+FD+RYLRP EV+ LIGD+TKA Sbjct 245 LQQEKPDDYVIATNETHSIKEFLDLAFTYVNLDWQKYVEFDERYLRPAEVELLIGDSTKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAALECEGK 328 + L W SV EL +MVDADM AL+ +G+ Sbjct 305 RQQLNWEPSVTFQELVHLMVDADMKALDAQGR 336 >gi|225165868|ref|ZP_03727642.1| GDP-mannose 4,6-dehydratase [Opitutaceae bacterium TAV2] gi|224799887|gb|EEG18342.1| GDP-mannose 4,6-dehydratase [Opitutaceae bacterium TAV2] Length=338 Score = 460 bits (1184), Expect = 1e-127, Method: Compositional matrix adjust. Identities = 221/331 (67%), Positives = 259/331 (79%), Gaps = 3/331 (0%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+ALITGITGQDGSYLAELLLAKGYEVHG+IRRASTFNTSRIDHLY DPH G R+FLH Sbjct 1 MKKALITGITGQDGSYLAELLLAKGYEVHGIIRRASTFNTSRIDHLYKDPHVNGVRMFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL D ++V LL ++PDE+YNLAAQSHVRVSFD P +TGD G+G+ R+LEA+R + Sbjct 61 YGDLTDSVQMVKLLYDLKPDEIYNLAAQSHVRVSFDVPEYTGDVDGLGAQRILEAIRETG 120 Query 121 V--HCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVN 177 + R+YQASSSEMFG PQ E TPF+PRSPYG AKVY+YW T NYRE+Y L A N Sbjct 121 LVKKVRYYQASSSEMFGKVQQVPQTETTPFWPRSPYGCAKVYAYWLTVNYRESYNLHASN 180 Query 178 GILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRML 237 GILFNHESPRRGETFVTRKITRA RIK G+Q +YMGNLDA RDWGYA EYVE MW ML Sbjct 181 GILFNHESPRRGETFVTRKITRAATRIKMGLQDALYMGNLDAQRDWGYAKEYVEMMWLML 240 Query 238 QTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAA 297 Q D+PDD+V+AT +V+EF + F+H GLDW++YVK+D RY RP EV+ LIGD KA Sbjct 241 QQDKPDDYVVATNETHSVKEFIQETFDHLGLDWKKYVKYDARYERPAEVELLIGDPAKAR 300 Query 298 ELLGWRASVHTDELARIMVDADMAALECEGK 328 + LGW V EL +IMVDAD+ + E + Sbjct 301 KQLGWEPKVRFKELVKIMVDADLDLAKREAQ 331 >gi|300865719|ref|ZP_07110483.1| GDP-mannose 4,6-dehydratase [Oscillatoria sp. PCC 6506] gi|300336275|emb|CBN55633.1| GDP-mannose 4,6-dehydratase [Oscillatoria sp. PCC 6506] Length=343 Score = 459 bits (1180), Expect = 4e-127, Method: Compositional matrix adjust. Identities = 218/328 (67%), Positives = 259/328 (79%), Gaps = 5/328 (1%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYL+ELLL KGYEVHG+IRR+STFNT RIDH+YVDPH ARLFLHY Sbjct 5 KRALITGITGQDGSYLSELLLEKGYEVHGIIRRSSTFNTDRIDHIYVDPHSENARLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR- 120 GDL DGT L +L ++P E+YNL AQSHVRVSFD P +T D G+G++RLLEA+R R Sbjct 65 GDLTDGTTLRRILEEVKPAEIYNLGAQSHVRVSFDAPEYTVDAVGLGTLRLLEAIRDYRH 124 Query 121 ---VHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 + RFYQA SSEM+G PQ E TPFYPRSPY AKVY++W T NYRE+YG+FA Sbjct 125 RTGIEVRFYQAGSSEMYGLVQEVPQKETTPFYPRSPYACAKVYAHWQTVNYRESYGMFAS 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRAVARI AG Q ++Y+GNLD+ RDWGYA +YV+ MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRAVARIVAGKQKKLYLGNLDSKRDWGYAKDYVKAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ DEPDD+V+AT ++REF AF LDW +YV+FD+RYLRP EV+ LIGD+TKA Sbjct 245 LQHDEPDDYVVATNETHSIREFLDKAFNCVNLDWHEYVEFDERYLRPAEVELLIGDSTKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAALE 324 + LGW SV +EL ++MVD+D+ +LE Sbjct 305 RQKLGWEPSVTFEELVKLMVDSDIKSLE 332 >gi|206890367|ref|YP_002248314.1| GDP-mannose 4,6-dehydratase [Thermodesulfovibrio yellowstonii DSM 11347] gi|206742305|gb|ACI21362.1| GDP-mannose 4,6-dehydratase [Thermodesulfovibrio yellowstonii DSM 11347] Length=384 Score = 458 bits (1179), Expect = 4e-127, Method: Compositional matrix adjust. Identities = 227/350 (65%), Positives = 259/350 (74%), Gaps = 30/350 (8%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+ALITGITGQDGSYLAE LL+KGYEVHGLIRRASTFNT RIDH+Y+DPH P ARLFLH Sbjct 1 MKKALITGITGQDGSYLAEFLLSKGYEVHGLIRRASTFNTQRIDHIYIDPHMPEARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR 120 YGDL D +LV ++ I+PDE+Y+L AQSHVRVSFD P +TGD T +G+ RLLEAVR S Sbjct 61 YGDLSDSGQLVHIIYNIQPDEIYHLGAQSHVRVSFDMPEYTGDITALGTTRLLEAVRRSG 120 Query 121 VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL 180 + RFYQASSSEMFGASPPPQNE T FYPRSPY AAKVY+YW T NYREAYGLFA NGIL Sbjct 121 IKTRFYQASSSEMFGASPPPQNEKTLFYPRSPYAAAKVYAYWVTVNYREAYGLFACNGIL 180 Query 181 FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD 240 FNHESPRRGETFVTRKITRA+A I AG Q ++Y+GNL+A RDWG+APEYVE MW MLQ D Sbjct 181 FNHESPRRGETFVTRKITRALAHILAGKQKKLYLGNLNAKRDWGFAPEYVEMMWLMLQAD 240 Query 241 EPDDFVLATGRGFTVREFARAAFEHAG----------------------LDWQQ------ 272 EPDD+V+ TG +VREF AF +AG LD +Q Sbjct 241 EPDDYVVGTGESHSVREFVEKAFSYAGIEIEWKGSGTDEKGIVSSLKENLDIEQRILNTG 300 Query 273 --YVKFDQRYLRPTEVDSLIGDATKAAELLGWRASVHTDELARIMVDADM 320 ++ D RY RPTEV+ L D TKA LGW+ DEL +IMVD DM Sbjct 301 DVVIEIDPRYFRPTEVEHLEADITKAKNKLGWQPRTTFDELVKIMVDYDM 350 >gi|345303818|ref|YP_004825720.1| GDP-mannose 4,6-dehydratase [Rhodothermus marinus SG0.5JP17-172] gi|345113051|gb|AEN73883.1| GDP-mannose 4,6-dehydratase [Rhodothermus marinus SG0.5JP17-172] Length=348 Score = 458 bits (1179), Expect = 5e-127, Method: Compositional matrix adjust. Identities = 220/324 (68%), Positives = 255/324 (79%), Gaps = 4/324 (1%) Query 1 VKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH 60 +K+ALITGITGQDG+YL E LL +GYEVHG+IRRASTFNT RIDHLY DPH P ARLFLH Sbjct 1 MKKALITGITGQDGAYLTEFLLERGYEVHGIIRRASTFNTDRIDHLYRDPHDPQARLFLH 60 Query 61 YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR--- 117 YGDL DGT L +L ++PDE+YNL AQSHV+VSF++P +T D G++RLLEAVR Sbjct 61 YGDLSDGTGLRHILERVQPDEIYNLGAQSHVKVSFEQPEYTVDIVATGTLRLLEAVRDFV 120 Query 118 -LSRVHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 S RFYQA SSEMFGA+PPPQNE TPFYPRSPY AAKV +YW NYREAYGLF Sbjct 121 RHSGKQVRFYQAGSSEMFGAAPPPQNEKTPFYPRSPYAAAKVAAYWYAVNYREAYGLFIC 180 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRA RIK G+Q ++Y+GNL+A RDWG+A +YVE MW M Sbjct 181 NGILFNHESPRRGETFVTRKITRAAGRIKMGLQDKLYLGNLEARRDWGFAGDYVEAMWLM 240 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ DEPDD+V+ATG +VREF AF LDW++YVK D RY RPTEVD L+GDA+KA Sbjct 241 LQQDEPDDYVIATGESHSVREFLELAFGMLDLDWRKYVKIDPRYFRPTEVDHLLGDASKA 300 Query 297 AELLGWRASVHTDELARIMVDADM 320 E LGWR V +EL R+MV+ D+ Sbjct 301 REKLGWRPRVSFEELVRMMVEHDL 324 >gi|254424664|ref|ZP_05038382.1| GDP-mannose 4,6-dehydratase [Synechococcus sp. PCC 7335] gi|196192153|gb|EDX87117.1| GDP-mannose 4,6-dehydratase [Synechococcus sp. PCC 7335] Length=356 Score = 458 bits (1178), Expect = 7e-127, Method: Compositional matrix adjust. Identities = 215/327 (66%), Positives = 258/327 (79%), Gaps = 5/327 (1%) Query 2 KRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLHY 61 KRALITGITGQDGSYLAELLL+KGYEVHG+IRR STFNT RIDH+Y DPH+ A+LFLHY Sbjct 5 KRALITGITGQDGSYLAELLLSKGYEVHGIIRRTSTFNTDRIDHIYEDPHKEDAKLFLHY 64 Query 62 GDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVR---- 117 GDL DGT L +L ++P+EVYNL AQSHVRVSFD P +T DT MG++RLLEA+R Sbjct 65 GDLNDGTMLRRILEQVQPNEVYNLGAQSHVRVSFDSPEYTVDTVAMGALRLLEAIRDYQQ 124 Query 118 LSRVHCRFYQASSSEMFG-ASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAV 176 +R RFYQA SSEM+G PQ+E TPFYPRSPY AKVY++W T NYRE+Y +FA Sbjct 125 RTRSEVRFYQAGSSEMYGKVQHVPQSEETPFYPRSPYSCAKVYAHWQTINYRESYDMFAT 184 Query 177 NGILFNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRM 236 NGILFNHESPRRGETFVTRKITRA+ARI G Q ++Y+GNLDA RDWGYA +YV+ MW M Sbjct 185 NGILFNHESPRRGETFVTRKITRAIARIVTGQQKKLYLGNLDAKRDWGYAKDYVKAMWLM 244 Query 237 LQTDEPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKA 296 LQ D+PDDFV+ATG +++R+F AF+H LDW +V FD+RYLRP EVD LIGD +KA Sbjct 245 LQHDQPDDFVIATGETYSIRQFLDIAFQHVNLDWTDFVAFDERYLRPAEVDLLIGDPSKA 304 Query 297 AELLGWRASVHTDELARIMVDADMAAL 323 +LGW+ V +EL ++MVDAD+ + Sbjct 305 KRILGWQPEVSFEELVKLMVDADLEVV 331 Lambda K H 0.321 0.136 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 617544973600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40