BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1538c Length=326 Score E Sequences producing significant alignments: (Bits) Value gi|15608676|ref|NP_216054.1| L-aparaginase ansA [Mycobacterium t... 632 3e-179 gi|289757654|ref|ZP_06517032.1| L-asparaginase [Mycobacterium tu... 630 1e-178 gi|254364410|ref|ZP_04980456.1| L-aparaginase ansA [Mycobacteriu... 628 4e-178 gi|308370754|ref|ZP_07667011.1| L-asparaginase ansA [Mycobacteri... 619 2e-175 gi|339294513|gb|AEJ46624.1| L-asparaginase ansA [Mycobacterium t... 617 8e-175 gi|308375609|ref|ZP_07668070.1| L-asparaginase ansA [Mycobacteri... 607 6e-172 gi|308377759|ref|ZP_07668587.1| L-asparaginase ansA [Mycobacteri... 517 8e-145 gi|289750105|ref|ZP_06509483.1| LOW QUALITY PROTEIN: L-asparagin... 451 8e-125 gi|118617187|ref|YP_905519.1| L-aparaginase AnsA [Mycobacterium ... 424 1e-116 gi|183982373|ref|YP_001850664.1| L-aparaginase AnsA [Mycobacteri... 418 5e-115 gi|240167930|ref|ZP_04746589.1| L-aparaginase AnsA [Mycobacteriu... 397 2e-108 gi|342860880|ref|ZP_08717530.1| putative L-asparaginase [Mycobac... 367 1e-99 gi|15827609|ref|NP_301872.1| L-asparaginase/L-glutaminase [Mycob... 366 3e-99 gi|118464462|ref|YP_882414.1| L-asparaginase [Mycobacterium aviu... 351 8e-95 gi|254775681|ref|ZP_05217197.1| L-asparaginase [Mycobacterium av... 349 3e-94 gi|315444559|ref|YP_004077438.1| asparaginase [Mycobacterium sp.... 345 8e-93 gi|145224225|ref|YP_001134903.1| asparaginase/glutaminase [Mycob... 342 4e-92 gi|333990826|ref|YP_004523440.1| L-asparaginase AnsA [Mycobacter... 341 9e-92 gi|41407347|ref|NP_960183.1| AnsA [Mycobacterium avium subsp. pa... 340 2e-91 gi|120403756|ref|YP_953585.1| asparaginase/glutaminase [Mycobact... 328 5e-88 gi|126435693|ref|YP_001071384.1| asparaginase [Mycobacterium sp.... 315 6e-84 gi|108800060|ref|YP_640257.1| asparaginase/glutaminase [Mycobact... 308 1e-81 gi|118472191|ref|YP_887488.1| L-asparaginase [Mycobacterium smeg... 300 3e-79 gi|296164414|ref|ZP_06846988.1| asparaginase [Mycobacterium para... 273 4e-71 gi|169629786|ref|YP_001703435.1| L-asparaginase [Mycobacterium a... 251 9e-65 gi|222082256|ref|YP_002541621.1| L-asparaginase [Agrobacterium r... 192 8e-47 gi|226309127|ref|YP_002769087.1| L-asparaginase [Rhodococcus ery... 189 7e-46 gi|226363778|ref|YP_002781560.1| L-asparaginase [Rhodococcus opa... 187 3e-45 gi|111021423|ref|YP_704395.1| asparaginase [Rhodococcus jostii R... 187 3e-45 gi|302546176|ref|ZP_07298518.1| L-asparaginase [Streptomyces hyg... 182 9e-44 gi|153010720|ref|YP_001371934.1| asparaginase/glutaminase [Ochro... 181 1e-43 gi|239833704|ref|ZP_04682032.1| Probable L-asparaginase [Ochroba... 180 2e-43 gi|317508617|ref|ZP_07966275.1| asparaginase [Segniliparus rugos... 180 3e-43 gi|332716529|ref|YP_004443995.1| L-asparaginase [Agrobacterium s... 179 4e-43 gi|319950010|ref|ZP_08023990.1| L-asparaginase [Dietzia cinnamea... 176 5e-42 gi|335035712|ref|ZP_08529046.1| L-asparaginase [Agrobacterium sp... 167 2e-39 gi|338821341|gb|EGP55310.1| L-asparaginase [Agrobacterium tumefa... 163 3e-38 gi|108805636|ref|YP_645573.1| asparaginase [Rubrobacter xylanoph... 161 2e-37 gi|152964029|ref|YP_001359813.1| asparaginase/glutaminase [Kineo... 161 2e-37 gi|15891159|ref|NP_356831.1| L-asparaginase [Agrobacterium tumef... 161 2e-37 gi|227503299|ref|ZP_03933348.1| possible asparaginase [Corynebac... 160 2e-37 gi|227504707|ref|ZP_03934756.1| L-asparaginase [Corynebacterium ... 160 4e-37 gi|340029682|ref|ZP_08665745.1| asparaginase/glutaminase [Paraco... 159 8e-37 gi|227833476|ref|YP_002835183.1| L-asparaginase [Corynebacterium... 157 2e-36 gi|119386949|ref|YP_918004.1| asparaginase/glutaminase [Paracocc... 157 2e-36 gi|237785356|ref|YP_002906061.1| L-asparaginase [Corynebacterium... 156 5e-36 gi|296393821|ref|YP_003658705.1| asparaginase/glutaminase [Segni... 154 2e-35 gi|62290811|ref|YP_222604.1| L-asparaginase type II [Brucella ab... 153 3e-35 gi|337290034|ref|YP_004629055.1| L-asparaginase [Corynebacterium... 153 3e-35 gi|261221012|ref|ZP_05935293.1| asparaginase/glutaminase [Brucel... 153 4e-35 >gi|15608676|ref|NP_216054.1| L-aparaginase ansA [Mycobacterium tuberculosis H37Rv] gi|15841005|ref|NP_336042.1| L-asparaginase [Mycobacterium tuberculosis CDC1551] gi|31792724|ref|NP_855217.1| L-aparaginase ansA [Mycobacterium bovis AF2122/97] 53 more sequence titles Length=326 Score = 632 bits (1629), Expect = 3e-179, Method: Compositional matrix adjust. Identities = 326/326 (100%), Positives = 326/326 (100%), Gaps = 0/326 (0%) Query 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA Sbjct 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 Query 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA Sbjct 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 Query 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE Sbjct 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 Query 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA Sbjct 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 Query 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP 300 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP Sbjct 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP 300 Query 301 PSQARVLLMAALAANSPVADVIDRWG 326 PSQARVLLMAALAANSPVADVIDRWG Sbjct 301 PSQARVLLMAALAANSPVADVIDRWG 326 >gi|289757654|ref|ZP_06517032.1| L-asparaginase [Mycobacterium tuberculosis T85] gi|294996505|ref|ZP_06802196.1| probable L-asparaginase [Mycobacterium tuberculosis 210] gi|289713218|gb|EFD77230.1| L-asparaginase [Mycobacterium tuberculosis T85] gi|326903168|gb|EGE50101.1| L-asparaginase ansA [Mycobacterium tuberculosis W-148] Length=326 Score = 630 bits (1625), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 325/326 (99%), Positives = 325/326 (99%), Gaps = 0/326 (0%) Query 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA Sbjct 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 Query 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA Sbjct 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 Query 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE Sbjct 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 Query 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA Sbjct 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 Query 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP 300 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGA YGPGHDLVEAGAVMVPRLP Sbjct 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGASYGPGHDLVEAGAVMVPRLP 300 Query 301 PSQARVLLMAALAANSPVADVIDRWG 326 PSQARVLLMAALAANSPVADVIDRWG Sbjct 301 PSQARVLLMAALAANSPVADVIDRWG 326 >gi|254364410|ref|ZP_04980456.1| L-aparaginase ansA [Mycobacterium tuberculosis str. Haarlem] gi|134149924|gb|EBA41969.1| L-aparaginase ansA [Mycobacterium tuberculosis str. Haarlem] Length=326 Score = 628 bits (1620), Expect = 4e-178, Method: Compositional matrix adjust. Identities = 325/326 (99%), Positives = 325/326 (99%), Gaps = 0/326 (0%) Query 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA Sbjct 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 Query 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA Sbjct 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 Query 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE Sbjct 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 Query 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 SLGFTSGGV LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA Sbjct 181 SLGFTSGGVPLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 Query 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP 300 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP Sbjct 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLP 300 Query 301 PSQARVLLMAALAANSPVADVIDRWG 326 PSQARVLLMAALAANSPVADVIDRWG Sbjct 301 PSQARVLLMAALAANSPVADVIDRWG 326 >gi|308370754|ref|ZP_07667011.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu003] gi|308371991|ref|ZP_07667280.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu004] gi|308374337|ref|ZP_07667763.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu006] 6 more sequence titles Length=321 Score = 619 bits (1596), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 320/321 (99%), Positives = 321/321 (100%), Gaps = 0/321 (0%) Query 6 VRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 65 +RNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK Sbjct 1 MRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 60 Query 66 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD Sbjct 61 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 120 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT Sbjct 121 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 180 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN Sbjct 181 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 240 Query 246 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR 305 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR Sbjct 241 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR 300 Query 306 VLLMAALAANSPVADVIDRWG 326 VLLMAALAANSPVADVIDRWG Sbjct 301 VLLMAALAANSPVADVIDRWG 321 >gi|339294513|gb|AEJ46624.1| L-asparaginase ansA [Mycobacterium tuberculosis CCDC5079] gi|339298149|gb|AEJ50259.1| L-asparaginase ansA [Mycobacterium tuberculosis CCDC5180] Length=321 Score = 617 bits (1591), Expect = 8e-175, Method: Compositional matrix adjust. Identities = 319/321 (99%), Positives = 320/321 (99%), Gaps = 0/321 (0%) Query 6 VRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 65 +RNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK Sbjct 1 MRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 60 Query 66 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD Sbjct 61 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 120 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT Sbjct 121 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 180 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN Sbjct 181 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 240 Query 246 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR 305 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGA YGPGHDLVEAGAVMVPRLPPSQAR Sbjct 241 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGASYGPGHDLVEAGAVMVPRLPPSQAR 300 Query 306 VLLMAALAANSPVADVIDRWG 326 VLLMAALAANSPVADVIDRWG Sbjct 301 VLLMAALAANSPVADVIDRWG 321 >gi|308375609|ref|ZP_07668070.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu007] gi|308380106|ref|ZP_07669119.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu011] gi|308400683|ref|ZP_07669397.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu012] gi|54036771|sp|P63628.1|ASPG_MYCBO RecName: Full=Probable L-asparaginase; Short=L-ASNase; AltName: Full=L-asparagine amidohydrolase gi|54040839|sp|P63627.1|ASPG_MYCTU RecName: Full=Probable L-asparaginase; Short=L-ASNase; AltName: Full=L-asparagine amidohydrolase gi|308345755|gb|EFP34606.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu007] gi|308362574|gb|EFP51425.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu011] gi|308366238|gb|EFP55089.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu012] Length=315 Score = 607 bits (1566), Expect = 6e-172, Method: Compositional matrix adjust. Identities = 315/315 (100%), Positives = 315/315 (100%), Gaps = 0/315 (0%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW Sbjct 1 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 60 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG Sbjct 61 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 120 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL Sbjct 121 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 180 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI Sbjct 181 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 240 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA Sbjct 241 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 300 Query 312 LAANSPVADVIDRWG 326 LAANSPVADVIDRWG Sbjct 301 LAANSPVADVIDRWG 315 >gi|308377759|ref|ZP_07668587.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu009] gi|308354708|gb|EFP43559.1| L-asparaginase ansA [Mycobacterium tuberculosis SUMu009] Length=268 Score = 517 bits (1332), Expect = 8e-145, Method: Compositional matrix adjust. Identities = 268/268 (100%), Positives = 268/268 (100%), Gaps = 0/268 (0%) Query 59 MALDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLT 118 MALDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLT Sbjct 1 MALDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLT 60 Query 119 GAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFA 178 GAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFA Sbjct 61 GAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFA 120 Query 179 GESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVL 238 GESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVL Sbjct 121 GESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVL 180 Query 239 EALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPR 298 EALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPR Sbjct 181 EALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPR 240 Query 299 LPPSQARVLLMAALAANSPVADVIDRWG 326 LPPSQARVLLMAALAANSPVADVIDRWG Sbjct 241 LPPSQARVLLMAALAANSPVADVIDRWG 268 >gi|289750105|ref|ZP_06509483.1| LOW QUALITY PROTEIN: L-asparaginase ansA [Mycobacterium tuberculosis T92] gi|289690692|gb|EFD58121.1| LOW QUALITY PROTEIN: L-asparaginase ansA [Mycobacterium tuberculosis T92] Length=267 Score = 451 bits (1160), Expect = 8e-125, Method: Compositional matrix adjust. Identities = 257/267 (97%), Positives = 258/267 (97%), Gaps = 4/267 (1%) Query 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA Sbjct 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 Query 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA Sbjct 61 LDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGA 120 Query 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE Sbjct 121 MLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGE 180 Query 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA Sbjct 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 Query 241 LGSGNAGAAVIEG----VRRHCRDGSD 263 LGSGNAGAAVIEG + R R G D Sbjct 241 LGSGNAGAAVIEGSPSPLSRRERSGGD 267 >gi|118617187|ref|YP_905519.1| L-aparaginase AnsA [Mycobacterium ulcerans Agy99] gi|118569297|gb|ABL04048.1| L-aparaginase AnsA [Mycobacterium ulcerans Agy99] Length=329 Score = 424 bits (1090), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 248/332 (75%), Positives = 268/332 (81%), Gaps = 9/332 (2%) Query 1 MGANHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMA 60 M VR+DP MARLTVITTGGTIST+ G DGV RP+ GA L A + D D+E+VDLMA Sbjct 1 MPMTWVRDDPTMARLTVITTGGTISTSTGTDGVRRPSRNGAQLTAAVSGDLDVEIVDLMA 60 Query 61 LDSSKLTPADWDRIGAAVQEAF-RG-----GADGVVITHGTDTLEETALWLDLTYAGSRP 114 LDSS+L PADWDRI AA+ RG G DGVVITHGTDTLEETALWLDLTY+GS P Sbjct 61 LDSSQLVPADWDRIRAALHAITGRGADRPNGPDGVVITHGTDTLEETALWLDLTYSGSTP 120 Query 115 VVLTGAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDL 174 VVLTGAM S+DA ADGPANLRDAL VA DPA RD GVLV F RVL+PLGL K A DL Sbjct 121 VVLTGAMRSSDAADADGPANLRDALIVAGDPAVRDCGVLVCFARRVLEPLGLRKAATDDL 180 Query 175 CGFAGESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGAR 234 GFAGE LG + V L R K+RPYLGD+ AA APRVDIVAVYPGSDAVA+DACVAAGAR Sbjct 181 SGFAGELLGTVTDEVTLRRAKSRPYLGDVLAADAPRVDIVAVYPGSDAVALDACVAAGAR 240 Query 235 AVVLEALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAV 294 A+VLEALGSGNAGAAVI+GVRRHC +G VVIAVSTRVAGARVGAGYGPGHDLV AGAV Sbjct 241 AIVLEALGSGNAGAAVIDGVRRHCGNG---VVIAVSTRVAGARVGAGYGPGHDLVAAGAV 297 Query 295 MVPRLPPSQARVLLMAALAANSPVADVIDRWG 326 MVPRLPPSQARVLLMAAL A P+ +VIDRWG Sbjct 298 MVPRLPPSQARVLLMAALTAELPIVEVIDRWG 329 >gi|183982373|ref|YP_001850664.1| L-aparaginase AnsA [Mycobacterium marinum M] gi|183175699|gb|ACC40809.1| L-aparaginase AnsA [Mycobacterium marinum M] Length=318 Score = 418 bits (1075), Expect = 5e-115, Method: Compositional matrix adjust. Identities = 244/321 (77%), Positives = 263/321 (82%), Gaps = 9/321 (2%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 MARLTVITTGGTIST+ G DGV RP+ GA L A + D D+E+VDLMALDSS+L PADW Sbjct 1 MARLTVITTGGTISTSTGTDGVRRPSRNGAQLTAAVSGDLDVEIVDLMALDSSQLVPADW 60 Query 72 DRIGAAVQEAF-RG-----GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 DRI AA+ RG G DGVVITHGTDTLEETALWLDLTY+GS PVVLTGAM S+D Sbjct 61 DRIRAALHAITGRGADRPNGPDGVVITHGTDTLEETALWLDLTYSGSTPVVLTGAMRSSD 120 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 A ADGPANLRDAL VA DPA RD GVLV F GRVL+PLGL K A DL GFAGE LG Sbjct 121 AADADGPANLRDALIVAGDPAVRDCGVLVCFAGRVLEPLGLRKAATDDLSGFAGELLGTV 180 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 + V L R K+RPYLGD+ AA APRVDIVAVYPGSDAVA+DACVAAGARA+VLEALGSGN Sbjct 181 TDEVTLRRAKSRPYLGDVLAADAPRVDIVAVYPGSDAVALDACVAAGARAIVLEALGSGN 240 Query 246 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR 305 AGAAVI+GVRRHC +G VVIAVSTRVAGARVGAGYGPGHDLV AGAVMVPRLPPSQAR Sbjct 241 AGAAVIDGVRRHCGNG---VVIAVSTRVAGARVGAGYGPGHDLVAAGAVMVPRLPPSQAR 297 Query 306 VLLMAALAANSPVADVIDRWG 326 VLLMAAL A P+ +VIDRWG Sbjct 298 VLLMAALTAELPIVEVIDRWG 318 >gi|240167930|ref|ZP_04746589.1| L-aparaginase AnsA [Mycobacterium kansasii ATCC 12478] Length=312 Score = 397 bits (1019), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 234/315 (75%), Positives = 254/315 (81%), Gaps = 3/315 (0%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M RL+VITTGGTI+T+ G DGV RP+ GA L A D DI+VVDLMALDSS LTP DW Sbjct 1 MGRLSVITTGGTIATSTGADGVRRPSRSGAELTAAAGADLDIDVVDLMALDSSLLTPVDW 60 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DRI AAVQ A GGA GVVITHGTDTLEETALWLDLTY+G PVV+TGAM S+DA ADG Sbjct 61 DRIRAAVQAAVDGGAVGVVITHGTDTLEETALWLDLTYSGDTPVVITGAMHSSDAADADG 120 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 P NLRDAL +AAD ARD GVLV GRVLQPLGL K DL GFAG+ LG + V + Sbjct 121 PVNLRDALTLAADATARDHGVLVCLAGRVLQPLGLRKAVTDDLSGFAGKLLGTVTETVTM 180 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T K RPYLG+L AA APRVDIVAVYPG DAVA+DA VAAGARA+VLEALGSGNAG+AVI Sbjct 181 TSPKQRPYLGELCAAEAPRVDIVAVYPGCDAVALDAYVAAGARAIVLEALGSGNAGSAVI 240 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 + RRH DG VV+AVSTRVAGARVGAGYGPGHDLV+AGAVMVPRLPPSQARVLLMAA Sbjct 241 DAARRHSGDG---VVVAVSTRVAGARVGAGYGPGHDLVDAGAVMVPRLPPSQARVLLMAA 297 Query 312 LAANSPVADVIDRWG 326 LAA PVADV+DRWG Sbjct 298 LAAGLPVADVVDRWG 312 >gi|342860880|ref|ZP_08717530.1| putative L-asparaginase [Mycobacterium colombiense CECT 3035] gi|342131904|gb|EGT85161.1| putative L-asparaginase [Mycobacterium colombiense CECT 3035] Length=318 Score = 367 bits (943), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 227/321 (71%), Positives = 254/321 (80%), Gaps = 3/321 (0%) Query 6 VRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 65 +RND MARLTVI TGGTIST G DGV RP++ G+ L A D++VVDL+A+DSS+ Sbjct 1 MRNDASMARLTVIATGGTISTGTGADGVHRPSYTGSDLTAPFREGHDVDVVDLLAVDSSE 60 Query 66 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 LT ADWDRI AV A GGADGVV+ HGTDT+EE+ALWL+LTYAG PVVLTGAM SAD Sbjct 61 LTLADWDRIRDAVTAAVDGGADGVVVLHGTDTMEESALWLELTYAGRAPVVLTGAMRSAD 120 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 AP ADGPAN+RDALAVAA PAARDLGVL+ F GRVLQPLG+ KVA DL GF G LG Sbjct 121 APDADGPANVRDALAVAASPAARDLGVLLCFAGRVLQPLGMSKVATEDLSGFTGRPLGSV 180 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 +G V LT KTRP++G+L A APRVDIVA Y GSDAVA+DACVAAGAR VVLEALGSGN Sbjct 181 AGDVSLTGPKTRPFVGELRATGAPRVDIVAAYLGSDAVALDACVAAGARGVVLEALGSGN 240 Query 246 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQAR 305 AG AV++ VRRHC DG VV+AVSTRV G VGA YGPGHD+ AGAVMVPRL P QAR Sbjct 241 AGPAVVDAVRRHCGDG---VVVAVSTRVPGGSVGASYGPGHDMAAAGAVMVPRLRPPQAR 297 Query 306 VLLMAALAANSPVADVIDRWG 326 VLL+AALAA PVADV+ RWG Sbjct 298 VLLIAALAAGLPVADVVARWG 318 >gi|15827609|ref|NP_301872.1| L-asparaginase/L-glutaminase [Mycobacterium leprae TN] gi|221230086|ref|YP_002503502.1| L-asparaginase/L-glutaminase [Mycobacterium leprae Br4923] gi|6685257|sp|Q9X7E6.1|ASPG_MYCLE RecName: Full=Probable L-asparaginase; Short=L-ASNase; AltName: Full=L-asparagine amidohydrolase gi|4539132|emb|CAB39578.1| putative L-asparaginase or L-glutaminase [Mycobacterium leprae] gi|13093160|emb|CAC31579.1| L-asparaginase/L-glutaminase [Mycobacterium leprae] gi|219933193|emb|CAR71293.1| L-asparaginase/L-glutaminase [Mycobacterium leprae Br4923] Length=310 Score = 366 bits (939), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 227/315 (73%), Positives = 252/315 (80%), Gaps = 5/315 (1%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M+RLTVI TGGTIST+ DGV RP + G L A + D++VVDLM +DSS+L P DW Sbjct 1 MSRLTVIATGGTISTSTDHDGVRRPAYSGTELTA--HVAVDVDVVDLMTVDSSQLIPTDW 58 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DRI AAV A R GA GVV+THGTDT+EETALWLDLTYAG+ PVVLTGAM SADAP ADG Sbjct 59 DRIRAAVHTATRNGARGVVVTHGTDTMEETALWLDLTYAGNVPVVLTGAMRSADAPNADG 118 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 P NLR+ALAVAA PAAR +GVLVSF GRVLQPLGL K A DL GFAGE LG +S G L Sbjct 119 PTNLREALAVAASPAARGVGVLVSFAGRVLQPLGLRKAATQDLSGFAGELLGTSSSGFAL 178 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T KTRPYLGDL AA APRVDIVA Y GSD+VA+DA V+ GAR +VLEALGSGNAGAAV+ Sbjct 179 TAAKTRPYLGDLCAADAPRVDIVAAYLGSDSVALDAYVSTGARGIVLEALGSGNAGAAVV 238 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 +GVRRHC +G +VIAVSTRV V AGYGPGHDLVEAGAV+VP L PSQ RVLLMAA Sbjct 239 DGVRRHCHNG---IVIAVSTRVPEGHVSAGYGPGHDLVEAGAVLVPWLRPSQVRVLLMAA 295 Query 312 LAANSPVADVIDRWG 326 LAAN P+ADVI+RWG Sbjct 296 LAANLPIADVIERWG 310 >gi|118464462|ref|YP_882414.1| L-asparaginase [Mycobacterium avium 104] gi|118165749|gb|ABK66646.1| probable L-asparaginase [Mycobacterium avium 104] Length=312 Score = 351 bits (901), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 230/315 (74%), Positives = 248/315 (79%), Gaps = 3/315 (0%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 MARLTVI TGGTIST G DGV RP + GA L A D D+EVVDL+A+DSS+LT ADW Sbjct 1 MARLTVIATGGTISTGTGADGVHRPCYRGADLTAPFRADHDVEVVDLLAVDSSELTLADW 60 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DR+ AV A GGADGVVI HGTDT+EETALWLDLTY G PVVLTGAM SADAP ADG Sbjct 61 DRMRGAVTAALDGGADGVVILHGTDTMEETALWLDLTYDGPAPVVLTGAMRSADAPDADG 120 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 P N+RDALAVAA PAAR LGVL+ F GRVLQPLGL KVA DL GFAG +G +G V L Sbjct 121 PGNVRDALAVAAHPAARGLGVLLCFAGRVLQPLGLSKVATEDLSGFAGRLVGTVAGDVAL 180 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T KTRPYLGDLGAA APRVDIVA Y GSDAVA+DACVAAGARAVVLEALGSGNAG AV+ Sbjct 181 TGPKTRPYLGDLGAAAAPRVDIVAAYLGSDAVALDACVAAGARAVVLEALGSGNAGPAVV 240 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 + VRRHC G VVIAVSTRV G RVGA YGPGH++ AGAV VP L P QARVLL+AA Sbjct 241 DAVRRHCGTG---VVIAVSTRVPGGRVGASYGPGHEMAAAGAVPVPTLRPPQARVLLIAA 297 Query 312 LAANSPVADVIDRWG 326 LAA P ADV+ RWG Sbjct 298 LAAGLPAADVLGRWG 312 >gi|254775681|ref|ZP_05217197.1| L-asparaginase [Mycobacterium avium subsp. avium ATCC 25291] Length=312 Score = 349 bits (896), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 229/315 (73%), Positives = 247/315 (79%), Gaps = 3/315 (0%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 MARLTVI TGGTIST G DGV RP + GA L A D D+EVVDL+A+DSS+LT ADW Sbjct 1 MARLTVIATGGTISTGTGADGVHRPCYSGADLTAPFRADHDVEVVDLLAVDSSELTLADW 60 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DR+ AV A GGADGVVI HGTDT+EETALWLDLTY G PVVLTGAM SADAP ADG Sbjct 61 DRMREAVTAALDGGADGVVILHGTDTMEETALWLDLTYDGPAPVVLTGAMRSADAPDADG 120 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 P N+RDALAVAA PAAR LGVL+ F GRVLQPLGL KVA DL GFAG +G +G V L Sbjct 121 PGNVRDALAVAAHPAARGLGVLLCFAGRVLQPLGLSKVATEDLSGFAGRLVGTVAGDVAL 180 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T KTRPYLGDLGAA APRVDIVA Y GSDAVA+DACVAAGARAVVLEALGSGNAG AV+ Sbjct 181 TGPKTRPYLGDLGAAAAPRVDIVAAYLGSDAVALDACVAAGARAVVLEALGSGNAGPAVV 240 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 + VRRHC G VVIAVSTRV G RVGA YGPGH++ AGAV V L P QARVLL+AA Sbjct 241 DAVRRHCGTG---VVIAVSTRVPGGRVGASYGPGHEMAAAGAVPVSTLRPPQARVLLIAA 297 Query 312 LAANSPVADVIDRWG 326 LAA P ADV+ RWG Sbjct 298 LAAGLPAADVLGRWG 312 >gi|315444559|ref|YP_004077438.1| asparaginase [Mycobacterium sp. Spyr1] gi|315262862|gb|ADT99603.1| asparaginase [Mycobacterium sp. Spyr1] Length=303 Score = 345 bits (884), Expect = 8e-93, Method: Compositional matrix adjust. Identities = 194/318 (62%), Positives = 227/318 (72%), Gaps = 17/318 (5%) Query 10 PIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPA 69 P M RL VI TGGTIST++ DGV RPT GA L AGLD +EVVD +++DSS LTP+ Sbjct 2 PAMGRLVVIATGGTISTSSDADGVKRPTRSGADLTAGLD----VEVVDALSVDSSALTPS 57 Query 70 DWDRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 DWD I AAV++A DG+V+ HGTDT+EETALWL+LTY G+ PVVLTGA SAD P Sbjct 58 DWDLISAAVRQAASAETTDGIVVLHGTDTMEETALWLELTYDGAPPVVLTGAQRSADDPD 117 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG 188 DGPANLRDAL +AA P R GV+VSF G V + LG+HKVA D FAG Sbjct 118 GDGPANLRDALTLAALPELRGAGVVVSFAGAVFEALGVHKVATTDPQSFAGR-------- 169 Query 189 VRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGA 248 RLT +TRPYLG + AA APRVDIVA YPG++ A+DACVAAGAR +VL+A+GSGNAG Sbjct 170 -RLTGHRTRPYLGRVDAASAPRVDIVAAYPGANTAALDACVAAGARGIVLQAMGSGNAGR 228 Query 249 AVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLL 308 +I+GVRRHCR G V + VSTRV G V GYGPG DLV+AGAV+ P L P QARVLL Sbjct 229 ELIDGVRRHCRAG---VAVVVSTRVPGGPVRPGYGPGRDLVDAGAVVAPSLRPPQARVLL 285 Query 309 MAALAANSPVADVIDRWG 326 MAALA +P+ D RWG Sbjct 286 MAALATGAPIGDTFTRWG 303 >gi|145224225|ref|YP_001134903.1| asparaginase/glutaminase [Mycobacterium gilvum PYR-GCK] gi|145216711|gb|ABP46115.1| Asparaginase/glutaminase [Mycobacterium gilvum PYR-GCK] Length=300 Score = 342 bits (878), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 193/316 (62%), Positives = 226/316 (72%), Gaps = 17/316 (5%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M RL VI TGGTIST++ DGV RPT GA L AGLD +EVVD +++DSS LTP+DW Sbjct 1 MGRLVVIATGGTISTSSDADGVKRPTRSGADLTAGLD----VEVVDALSVDSSALTPSDW 56 Query 72 DRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 D I AAV++A DG+V+ HGTDT+EETALWL+LTY G+ PVVLTGA SAD P D Sbjct 57 DLISAAVRQAASAETTDGIVVLHGTDTMEETALWLELTYDGAPPVVLTGAQRSADDPDGD 116 Query 131 GPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVR 190 GPANLRDAL +AA P R GV+VSF G V + LG+HKVA D FAG R Sbjct 117 GPANLRDALTLAALPELRGAGVVVSFAGAVFEALGVHKVATTDPQSFAGR---------R 167 Query 191 LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAV 250 LT +TRPYLG + AA APRVDIVA YPG++ A+DACVAAGAR +VL+A+GSGNAG + Sbjct 168 LTGHRTRPYLGRVDAASAPRVDIVAAYPGANTAALDACVAAGARGIVLQAMGSGNAGREL 227 Query 251 IEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMA 310 I+GVRRHCR G V + VSTRV G V GYGPG DLV+AGAV+ P L P QARVLLMA Sbjct 228 IDGVRRHCRAG---VAVVVSTRVPGGPVRPGYGPGRDLVDAGAVVAPSLRPPQARVLLMA 284 Query 311 ALAANSPVADVIDRWG 326 ALA +P+ D RWG Sbjct 285 ALATGAPIGDTFTRWG 300 >gi|333990826|ref|YP_004523440.1| L-asparaginase AnsA [Mycobacterium sp. JDM601] gi|333486794|gb|AEF36186.1| L-asparaginase AnsA [Mycobacterium sp. JDM601] Length=313 Score = 341 bits (875), Expect = 9e-92, Method: Compositional matrix adjust. Identities = 211/318 (67%), Positives = 238/318 (75%), Gaps = 8/318 (2%) Query 11 IMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDS-DIEVVDLMALDSSKLTPA 69 + RLTVITTGGTI+ + DGV RPT GA L++G+ S ++ VVDLMA DSS+LTP Sbjct 2 VSKRLTVITTGGTIAASTDDDGVRRPTVHGADLVSGVGAGSAEVTVVDLMARDSSELTPV 61 Query 70 DWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGA 129 DW R+ AAV+ GGADGVV+THGTDT EETALWL+L Y G PVVLTGA SADAP A Sbjct 62 DWGRMLAAVRAGVDGGADGVVVTHGTDTCEETALWLELGYTGDAPVVLTGAQRSADAPDA 121 Query 130 DGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG- 188 DGP NLRDAL +AADPAAR LGVLV F G+VL PLGLHK DL GF+G +G +G Sbjct 122 DGPGNLRDALRLAADPAARGLGVLVCFAGQVLAPLGLHKTTTSDLTGFSGARVGTVAGDR 181 Query 189 VRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGA 248 V L K RP L PRVDIVA+Y G+DA A+DACVAAGAR +VLEALGSGNAG Sbjct 182 VSLDGEKVRPQ---LPVTAPPRVDIVALYAGADAAALDACVAAGARGIVLEALGSGNAGT 238 Query 249 AVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLL 308 AVI+GVRRHCRDG V +AVS+RV GARVGA YGPG LV+AGAVMVPRL P QARVLL Sbjct 239 AVIDGVRRHCRDG---VAVAVSSRVPGARVGAAYGPGRALVDAGAVMVPRLRPPQARVLL 295 Query 309 MAALAANSPVADVIDRWG 326 MAAL A PVAD +DRWG Sbjct 296 MAALCAGPPVADAVDRWG 313 >gi|41407347|ref|NP_960183.1| AnsA [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395699|gb|AAS03566.1| AnsA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457943|gb|EGO36933.1| L-asparaginase/GlutRNAGln amidotransferase subunit D [Mycobacterium avium subsp. paratuberculosis S397] Length=319 Score = 340 bits (871), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 231/322 (72%), Positives = 251/322 (78%), Gaps = 4/322 (1%) Query 6 VRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 65 +R+D MARLTVI TGGTIST G DGV RP + GA L A D D+EVVDL+A+DSS+ Sbjct 1 MRDDSPMARLTVIATGGTISTGTGADGVHRPCYSGADLTAPFRADHDVEVVDLLAVDSSE 60 Query 66 LTPADWDRI-GAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSA 124 LT ADWDR+ GA GGADGVVI HGTDT+EETALWLDLTY G PVVLTGAM SA Sbjct 61 LTLADWDRMRGAVTGALDGGGADGVVILHGTDTMEETALWLDLTYDGPAPVVLTGAMRSA 120 Query 125 DAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGF 184 DAP ADGP N+RDALAVAA PAAR LGVL+ F GRVLQPLGL KVA DL GFAG +G Sbjct 121 DAPDADGPGNVRDALAVAAHPAARGLGVLLCFAGRVLQPLGLSKVATEDLSGFAGRLVGT 180 Query 185 TSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSG 244 +G V LT KTRPYLGDLGAA APRVDIVA Y GSDAVA+DACVAAGARAVVLEALGSG Sbjct 181 VAGDVALTGPKTRPYLGDLGAAAAPRVDIVAAYLGSDAVALDACVAAGARAVVLEALGSG 240 Query 245 NAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQA 304 NAG AV++ VRRHC G VVIAVSTRV G RVGA YGPGH++ AGAV VP L P QA Sbjct 241 NAGPAVVDAVRRHCGTG---VVIAVSTRVPGGRVGASYGPGHEMAAAGAVPVPTLRPPQA 297 Query 305 RVLLMAALAANSPVADVIDRWG 326 RVLL+AALAA P ADV+ RWG Sbjct 298 RVLLIAALAAGLPAADVLGRWG 319 >gi|120403756|ref|YP_953585.1| asparaginase/glutaminase [Mycobacterium vanbaalenii PYR-1] gi|119956574|gb|ABM13579.1| asparaginase [Mycobacterium vanbaalenii PYR-1] Length=299 Score = 328 bits (842), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 206/315 (66%), Positives = 228/315 (73%), Gaps = 16/315 (5%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M RL VI TGGTI+T+ G DGV RP G L GLD +EVVD +A+DSS LTP DW Sbjct 1 MDRLVVIATGGTIATSTGTDGVKRPARSGTELTEGLD----VEVVDALAVDSSMLTPPDW 56 Query 72 DRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 DRIGAAV A GA G+V+THGTDT+EETALWL+LTY G PVVLTGA SADA ADG Sbjct 57 DRIGAAVLAAATSGASGIVVTHGTDTMEETALWLELTYDGEVPVVLTGAQRSADADDADG 116 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 PANLRDALAVAA P +R LGV+VSF G V + LGL+KVA DL F G GG R Sbjct 117 PANLRDALAVAARPESRGLGVVVSFAGAVFEALGLNKVATSDLQSFTGR---VVDGGRR- 172 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 RPYLG L AA APRVDIVA YPG+D A+DACVAAGAR +VLE LGSGNAGAA+I Sbjct 173 -----RPYLGALRAADAPRVDIVAAYPGADTAALDACVAAGARGIVLEGLGSGNAGAALI 227 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 GVRRHCRDG V +AVSTRVAG RV AGYGPG +LV+ A +VPRL P QARVLLMAA Sbjct 228 AGVRRHCRDG---VAVAVSTRVAGGRVSAGYGPGRELVDGDAFVVPRLRPPQARVLLMAA 284 Query 312 LAANSPVADVIDRWG 326 LAA + V RWG Sbjct 285 LAAGAAPGQVFARWG 299 >gi|126435693|ref|YP_001071384.1| asparaginase [Mycobacterium sp. JLS] gi|126235493|gb|ABN98893.1| asparaginase [Mycobacterium sp. JLS] Length=309 Score = 315 bits (807), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 205/315 (66%), Positives = 231/315 (74%), Gaps = 11/315 (3%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRI 74 L VITTGGTI+T+ DGV RPT GA L AGLD + VVD++ DSS+LTPADWDRI Sbjct 3 LVVITTGGTIATSTDADGVRRPTRRGADLTAGLD----VTVVDVLNKDSSQLTPADWDRI 58 Query 75 GAAVQEAF-RGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPA 133 AV G ADGVV+THGTDT+EETALWL+LTY G+ PVVLTGA ADAP ADGPA Sbjct 59 RDAVLAGTADGAADGVVVTHGTDTMEETALWLELTYDGTTPVVLTGAQRGADAPDADGPA 118 Query 134 NLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLTR 193 NLRDA+ VA DP AR LGVLVSF G V +PLGL KVA DL GF G +G + G R T Sbjct 119 NLRDAVTVAGDPEARGLGVLVSFAGTVRRPLGLRKVATEDLDGFDGPVVGRVADG-RFTV 177 Query 194 T--KTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T K RPYLGD+ A APRVDIV YPG DA A+ AC AAGARAVVLEALG+GNA VI Sbjct 178 TGPKVRPYLGDVSAERAPRVDIVTTYPGGDAAALSACAAAGARAVVLEALGAGNAPQPVI 237 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 +GVRR C DG V++AVSTRV G RV YGPG DL +AGA+MVP L P+QARVLLMAA Sbjct 238 DGVRRLCADG---VLVAVSTRVPGGRVRPAYGPGRDLADAGALMVPTLRPAQARVLLMAA 294 Query 312 LAANSPVADVIDRWG 326 LAA+ P A+V+ WG Sbjct 295 LAADVPAAEVLAEWG 309 >gi|108800060|ref|YP_640257.1| asparaginase/glutaminase [Mycobacterium sp. MCS] gi|119869186|ref|YP_939138.1| asparaginase/glutaminase [Mycobacterium sp. KMS] gi|108770479|gb|ABG09201.1| Asparaginase/glutaminase [Mycobacterium sp. MCS] gi|119695275|gb|ABL92348.1| Asparaginase/glutaminase [Mycobacterium sp. KMS] Length=309 Score = 308 bits (788), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 205/315 (66%), Positives = 231/315 (74%), Gaps = 11/315 (3%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRI 74 L VITTGGTI+T+ DGV RPT GA L AGLD + VVD++ DSS+LTPADWDRI Sbjct 3 LVVITTGGTIATSTDADGVRRPTRRGADLTAGLD----VTVVDVLNKDSSQLTPADWDRI 58 Query 75 GAAV-QEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPA 133 AV G ADGVV+THGTDT+EETALWL+LTY G+ PVVLTGA ADAP ADGPA Sbjct 59 RDAVLAGTAGGAADGVVVTHGTDTMEETALWLELTYDGTTPVVLTGAQRGADAPDADGPA 118 Query 134 NLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLTR 193 NLRDA+ VA DP AR LGVLVSF G V +PLGL KVA DL GF G +G + G R T Sbjct 119 NLRDAVTVAGDPEARGLGVLVSFAGTVRRPLGLRKVATEDLDGFDGPVVGRVADG-RFTV 177 Query 194 T--KTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 T K RPYLGD+ A APRVDIV YPG DA A+ AC AAGARAVVLEALG+GNA VI Sbjct 178 TGPKVRPYLGDVSAERAPRVDIVTTYPGGDAAALSACAAAGARAVVLEALGAGNAAQPVI 237 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAA 311 +GVRR C DG V++AVSTRV G RV YGPG DL +AGA+MVP L P+QARVLLMAA Sbjct 238 DGVRRLCADG---VLVAVSTRVPGGRVRPAYGPGRDLADAGALMVPTLRPAQARVLLMAA 294 Query 312 LAANSPVADVIDRWG 326 LAA+ P A+V+ WG Sbjct 295 LAADVPAAEVLAEWG 309 >gi|118472191|ref|YP_887488.1| L-asparaginase [Mycobacterium smegmatis str. MC2 155] gi|118173478|gb|ABK74374.1| L-asparaginase [Mycobacterium smegmatis str. MC2 155] Length=320 Score = 300 bits (767), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 188/300 (63%), Positives = 210/300 (70%), Gaps = 8/300 (2%) Query 32 GVLRPTHCGATLIAGLDMDS--DIEVVDLMALDSSKLTPADWDRIGAAVQEAFRG--GAD 87 GV RPT GA L A L + + VVDLM DSS LTP+DWD I AV +A G G D Sbjct 24 GVRRPTRRGAQLTAALTAPTAPTVSVVDLMTTDSSHLTPSDWDAIREAVAKATDGPGGPD 83 Query 88 GVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPANLRDALAVAADPAA 147 GVVITHGTD+LEETALWL+LT+ G PVV+TGA S+DAP ADGP NL DA+AVAA P A Sbjct 84 GVVITHGTDSLEETALWLELTHTGDTPVVITGAQRSSDAPEADGPRNLADAIAVAASPDA 143 Query 148 RDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTS-GGVRLTRTKTRPYLGDLGAA 206 R LGVLV F G V PLGLHK +L F+G +LG + G V LT KTRP LG L AA Sbjct 144 RGLGVLVCFAGTVRAPLGLHKRHTQELDAFSGTALGTVADGTVELTEDKTRPVLGALSAA 203 Query 207 VAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIEGVRRHCRDGSDPVV 266 APRVDIVA YPG+DA A+DACVAAGAR VVLEA+GSGN GAA+ EGV RH R G V Sbjct 204 AAPRVDIVAGYPGADAAALDACVAAGARGVVLEAMGSGNLGAALTEGVERHLRAG---VE 260 Query 267 IAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAALAANSPVADVIDRWG 326 I VSTRV G + YGPG L +AGAV+ PRL P QARVLLMAALAA PV +V WG Sbjct 261 IVVSTRVPGGVIAPDYGPGRRLADAGAVVAPRLRPPQARVLLMAALAAQRPVREVFSSWG 320 >gi|296164414|ref|ZP_06846988.1| asparaginase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900196|gb|EFG79628.1| asparaginase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=227 Score = 273 bits (697), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 162/228 (72%), Positives = 179/228 (79%), Gaps = 4/228 (1%) Query 6 VRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSK 65 VR+D M RLTVI TGGTIST G DGV RP + A L AGLD+D VVD++ALDSS+ Sbjct 4 VRDDLPMGRLTVIATGGTISTGTGADGVHRPAYGAAELAAGLDVD----VVDVLALDSSR 59 Query 66 LTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 L PADWDRI AV+ A GGADGVV+THGTDT+EE+ALWL+LT+AG PVVLTGAM AD Sbjct 60 LVPADWDRIRGAVRAAVDGGADGVVVTHGTDTMEESALWLELTHAGDVPVVLTGAMRGAD 119 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 AP ADGPANLR ALAVA PAAR LGVLV F GRVLQPLGL+KVA DL GFAGE +G Sbjct 120 APDADGPANLRAALAVAGSPAARGLGVLVCFAGRVLQPLGLNKVATDDLSGFAGELIGTV 179 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGA 233 +GGV L +KTRP LGDL AA APRVDIVA Y GSD VA+DACVAAGA Sbjct 180 NGGVTLAGSKTRPQLGDLSAARAPRVDIVAAYLGSDGVALDACVAAGA 227 >gi|169629786|ref|YP_001703435.1| L-asparaginase [Mycobacterium abscessus ATCC 19977] gi|169241753|emb|CAM62781.1| Probable L-asparaginase [Mycobacterium abscessus] Length=325 Score = 251 bits (642), Expect = 9e-65, Method: Compositional matrix adjust. Identities = 154/314 (50%), Positives = 195/314 (63%), Gaps = 8/314 (2%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRI 74 L ++TTGGTI+T G DG+ R G L+A ++ V DLM +DS+++TP W +I Sbjct 18 LVLLTTGGTIATEVGADGIARHASSGGDLLAA-SGQGNVLVEDLMTIDSAEMTPQRWQQI 76 Query 75 GAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPAN 134 A+V+ GA G+VI HGTDTLEETALWL LT A PVVLTGA S D P +DGP N Sbjct 77 AASVRGHVAAGATGIVIAHGTDTLEETALWLALTCAVPVPVVLTGAQRSGDHPESDGPGN 136 Query 135 LRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESL--GFTSGGVRLT 192 LRDAL VAA A LGV+V F G+V G+ KV GFAG G T Sbjct 137 LRDALTVAASGEA--LGVVVCFAGQVFPAAGIRKVDLTATAGFAGAPPVGQIRDGAFVRT 194 Query 193 RTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIE 252 + +LG + PRVD+V++YPG+DAVA+DA AGA+ +VLE++G+GNA AV E Sbjct 195 AQASSSFLGTVTRPALPRVDVVSLYPGADAVALDAFARAGAQGLVLESMGAGNANDAVTE 254 Query 253 GVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAAL 312 V RH +G + + V+TRV G + GY PG L++AGAV+ PRL QARVLLMAAL Sbjct 255 AVSRHIENG---IHVVVTTRVPGGLLSPGYAPGQKLIDAGAVVAPRLRAGQARVLLMAAL 311 Query 313 AANSPVADVIDRWG 326 A S + VIDR G Sbjct 312 ATGSDLVAVIDRLG 325 >gi|222082256|ref|YP_002541621.1| L-asparaginase [Agrobacterium radiobacter K84] gi|221726935|gb|ACM30024.1| L-asparaginase [Agrobacterium radiobacter K84] Length=315 Score = 192 bits (487), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 142/329 (44%), Positives = 184/329 (56%), Gaps = 24/329 (7%) Query 4 NHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALD 62 N + P++A +I TGGTI++ G DG P+ G L+ + + + + +DLM+ D Sbjct 2 NAQKIHPLVA---IIATGGTIASKRGADGASTPSLTGEDLLVLVPQVSARLRPIDLMSKD 58 Query 63 SSKLTPADWDRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAM 121 S+ LT AD RI AV + A GVV+ HGTD +EETAL + L +A S+PVV TGA Sbjct 59 SASLTLADMQRISDAVMQQLDDPAISGVVVLHGTDAMEETALLVHLQHATSKPVVFTGAQ 118 Query 122 LSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGF-AGE 180 +AD P ADGPANL A+ A D GVLVSFGGR+L G++K + F + Sbjct 119 FTADHPHADGPANLALAIETAMDQGNAGRGVLVSFGGRILPAWGVYKRSTDKPDAFRSAR 178 Query 181 SLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEA 240 +G P L A V RVDIVA+YPG DA + A + AGA +VL A Sbjct 179 PIGHVES----------PRLSTPVAGV--RVDIVAIYPGCDATHIQASLDAGANGIVLAA 226 Query 241 LGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVP 297 LGSGNA +I+ VRR C D PV+ VS+RV + A Y G GHDL AGAV Sbjct 227 LGSGNANPDIIDTVRR-CTDSGIPVI--VSSRVPDGLLVASYGGGGGGHDLAVAGAVHSH 283 Query 298 RLPPSQARVLLMAALAANSPVADVIDRWG 326 L PSQAR+LL A +AA SP + +G Sbjct 284 TLRPSQARILLAALIAARSPAGQISRAFG 312 >gi|226309127|ref|YP_002769087.1| L-asparaginase [Rhodococcus erythropolis PR4] gi|226188244|dbj|BAH36348.1| putative L-asparaginase [Rhodococcus erythropolis PR4] Length=320 Score = 189 bits (479), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 134/306 (44%), Positives = 173/306 (57%), Gaps = 15/306 (4%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M ++ V+TTGGTI++T G+ RP GA L+ D D+ VVD+M+ DSS +T AD Sbjct 1 MPKVAVVTTGGTIASTRDAHGISRPAITGADLLGNEQTDIDLRVVDVMSKDSSSMTFADM 60 Query 72 DRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 DR+ AV + + G D VV+ HGTDT+EETA LDL + RPVV TGA + D P +D Sbjct 61 DRVRDAVADELKDPGLDAVVVLHGTDTMEETAFLLDLHHDDRRPVVFTGAQRTFDHPESD 120 Query 131 GPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVR 190 +NL A+A D ++R GVL++FGG V G K L F SL Sbjct 121 ARSNLAAAIAAGLDISSRGRGVLIAFGGSVHPAAGTRKADTTALDAF--RSLPIDPA--L 176 Query 191 LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAV 250 L + P+ RVDI+AVYPG+D V +DACV+AGA +VL+ LGSGNA + Sbjct 177 LHTPEPLPW----HPISNTRVDIIAVYPGADRVQIDACVSAGANGLVLDGLGSGNANPTI 232 Query 251 IEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARVL 307 +E V R C PVV V+TRV + Y G GHDL+ AGAV L QARVL Sbjct 233 VEAV-RDCVGAHIPVV--VTTRVPSGPISPVYGGGGGGHDLIAAGAVFSTDLRAGQARVL 289 Query 308 LMAALA 313 L A L+ Sbjct 290 LAALLS 295 >gi|226363778|ref|YP_002781560.1| L-asparaginase [Rhodococcus opacus B4] gi|226242267|dbj|BAH52615.1| putative L-asparaginase [Rhodococcus opacus B4] Length=320 Score = 187 bits (474), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 129/299 (44%), Positives = 168/299 (57%), Gaps = 14/299 (4%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M ++ V+TTGGTI++ GV RP G+ L+ ++I VVD+M+ DSS +T AD Sbjct 1 MPKVAVVTTGGTIASRRDGQGVSRPVVAGSDLLGSARTGTEIRVVDVMSKDSSSMTFADL 60 Query 72 DRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 DR+ AV A D VV+ HGTDT+EETA +DL +A RPVV TGA + D P +D Sbjct 61 DRVRDAVTSELHDPALDAVVVLHGTDTMEETAFLVDLHHADPRPVVFTGAQRTFDHPESD 120 Query 131 GPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVR 190 NL DA+A DPA R GVL++FGG + + G K L F +G + Sbjct 121 ALTNLSDAIAAGTDPALRGAGVLIAFGGALHRASGTRKTDTTCLDAFRSV---HPTGDLP 177 Query 191 LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAV 250 R P+ G RVDIVA YPG+D V +DAC+AAGAR +VL+ LGSGNA A+ Sbjct 178 PQRPDPLPWHPISGT----RVDIVAAYPGADRVQIDACLAAGARGLVLDGLGSGNANPAI 233 Query 251 IEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARV 306 +E VR G + + V+TRV A Y G GHDLV AGA+ L QAR+ Sbjct 234 VEAVRDSTAAG---IPVVVTTRVPHGPTSATYGGGGGGHDLVSAGALFSTDLRAGQARI 289 >gi|111021423|ref|YP_704395.1| asparaginase [Rhodococcus jostii RHA1] gi|110820953|gb|ABG96237.1| asparaginase [Rhodococcus jostii RHA1] Length=320 Score = 187 bits (474), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 130/299 (44%), Positives = 166/299 (56%), Gaps = 14/299 (4%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M ++ ++TTGGTI++ GV RP G L+ +++ VVD+M+ DSS +T AD Sbjct 1 MPKVAIVTTGGTIASMRDGQGVSRPVVAGPDLLGNAWTGTELRVVDVMSKDSSSITFADM 60 Query 72 DRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 DR+ AV R D VV+ HGTDT+EETA +DL +A RPVV TGA + D P +D Sbjct 61 DRVRDAVTAELRDPDLDAVVVLHGTDTMEETAFLVDLHHADPRPVVFTGAQRTFDHPESD 120 Query 131 GPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVR 190 NL DA+A +DPA R GVL++FGG + G KV L F + R Sbjct 121 AQTNLADAVAAGSDPALRGAGVLIAFGGALHPASGTRKVDTTSLDAFRSVHPAGVTPRRR 180 Query 191 LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAV 250 L P G RVDIVA YPG+D V +DAC AAGA+ +VL+ LGSGNA A+ Sbjct 181 LDPLPWHPISGT-------RVDIVAAYPGADRVQIDACRAAGAQGLVLDGLGSGNANPAI 233 Query 251 IEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARV 306 +E V R C PVV V+TRV A Y G GHDLV AGA+ L QAR+ Sbjct 234 VEAV-RDCASAGIPVV--VTTRVPNGPTSATYGGGGGGHDLVSAGALFSTDLRAGQARI 289 >gi|302546176|ref|ZP_07298518.1| L-asparaginase [Streptomyces hygroscopicus ATCC 53653] gi|302463794|gb|EFL26887.1| L-asparaginase [Streptomyces himastatinicus ATCC 53653] Length=347 Score = 182 bits (461), Expect = 9e-44, Method: Compositional matrix adjust. Identities = 151/315 (48%), Positives = 171/315 (55%), Gaps = 17/315 (5%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDS--DIEVVDLMALDSSKLTPA 69 M R+ V++TGGTI+T G L+ L +E D+ L S LTPA Sbjct 1 MRRIVVLSTGGTIATRQDAHGTRLAADPADALLERLPRPPGVPVETRDVFCLGSYLLTPA 60 Query 70 DWDRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 D + A EA + GVV+THGTD+LEETA LDL +A RPVV TGAM ADAP Sbjct 61 DMREVAVAAHEALADESVRGVVVTHGTDSLEETAYLLDLFHADPRPVVFTGAMRPADAPD 120 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFA---GESLG-F 184 DGP NL DALAVA ARDLGVL+SF GR+ G K FA G LG Sbjct 121 GDGPRNLADALAVANAARARDLGVLISFDGRIYPARGTRKTHTVAPAAFAAPDGGPLGRV 180 Query 185 TSGGVRLTRTKTRPYLGDLGA--AVAP---RVDIVAVYPGSDAVAMDACVAAGARAVVLE 239 G V +T RP DL A AP R DIVAVYPG D A+ A AGARAVVLE Sbjct 181 ADGDVEITAAPLRPKPLDLAAFRPEAPERIRTDIVAVYPGCDIRALRAVADAGARAVVLE 240 Query 240 ALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGP--GHDLVEAGAVMVP 297 A G+GNA V V R G VV+A+STRV V A YG G DLV AGA+ Sbjct 241 ATGAGNANPQVAAEVARLVASG---VVVALSTRVHAGPVAAVYGNGGGADLVRAGAIPTG 297 Query 298 RLPPSQARVLLMAAL 312 L PSQARVLL A L Sbjct 298 TLRPSQARVLLTALL 312 >gi|153010720|ref|YP_001371934.1| asparaginase/glutaminase [Ochrobactrum anthropi ATCC 49188] gi|151562608|gb|ABS16105.1| Asparaginase/glutaminase [Ochrobactrum anthropi ATCC 49188] Length=312 Score = 181 bits (460), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 128/308 (42%), Positives = 178/308 (58%), Gaps = 22/308 (7%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLD-MDSDIEVVDLMALDSSKLTPADWDR 73 + VI TGGTI++ G DG P G L+ + +++++ VDLMA DS+ LT +D R Sbjct 8 IAVIATGGTIASKRGEDGASTPVLSGEDLLEFVPGLEAELRPVDLMAKDSASLTLSDMQR 67 Query 74 IGAAVQEAFRGG-ADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGP 132 I AV + G DG+V+ HGTD +EETAL + L S+PV+ TGA +AD P ADGP Sbjct 68 ISDAVGSCLKDGDFDGIVVLHGTDAMEETALLVHLQRRISKPVIFTGAQFTADHPQADGP 127 Query 133 ANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLT 192 NL A+ +A DPA D GVL++FGGR++ G +K N D + F S + Sbjct 128 ENLATAIRLACDPANADKGVLIAFGGRIVPAWGAYKF-NSD------SADAFRSARMIQI 180 Query 193 RTKTRPY-LGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 ++ P +GD R+D +A+YPG DA+ ++A +AAGA +VL ALGSGN V+ Sbjct 181 QSPVLPAPVGDR------RIDTIAIYPGCDALHIEASIAAGASGIVLAALGSGNTTPCVV 234 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARV---GAGYGPGHDLVEAGAVMVPRLPPSQARVLL 308 E VR R + +AVS+RV + G G G+DL EAGA+ L P QAR+LL Sbjct 235 EAVRECSRRN---IPVAVSSRVPEGLLTPGYGGGGGGYDLGEAGAIHAHTLRPGQARILL 291 Query 309 MAALAANS 316 A +A+ S Sbjct 292 AALIASGS 299 >gi|239833704|ref|ZP_04682032.1| Probable L-asparaginase [Ochrobactrum intermedium LMG 3301] gi|239821767|gb|EEQ93336.1| Probable L-asparaginase [Ochrobactrum intermedium LMG 3301] Length=312 Score = 180 bits (457), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 128/312 (42%), Positives = 182/312 (59%), Gaps = 30/312 (9%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGL--DMDSDIEVVDLMALDSSKLTPADWD 72 + +ITTGGTI++ G +G P G L+ GL ++ + V+LMA DS+ LT +D Sbjct 8 IALITTGGTIASKRGENGASTPVLSGGDLM-GLVPGPEAKLRAVNLMAKDSASLTLSDMQ 66 Query 73 RIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADG 131 RI +AV+ GA DG+++ HGTD +EETAL + L +PV+ TGA +AD P ADG Sbjct 67 RISSAVEAELEDGAVDGIIVLHGTDAMEETALLVQLQCRIGKPVIFTGAQFTADHPDADG 126 Query 132 PANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 P N+ A+ +A+DP+ + GV ++FGGR++ G +K F+SG Sbjct 127 PENIAAAIRLASDPSNAEKGVQIAFGGRIIPAWGAYK---------------FSSGNGDA 171 Query 192 TRTKTRPYLGDLGAAVAP----RVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAG 247 R+ RP L AP RVD++A+YPG DA+ ++A +AAGA +VL ALGSGNA Sbjct 172 FRS-ARPLLVQSPVFPAPVGDRRVDLIAIYPGCDALHIEASIAAGASGIVLAALGSGNAT 230 Query 248 AAVIEGVRRHCRDGSDPVVIAVSTRVAGARV---GAGYGPGHDLVEAGAVMVPRLPPSQA 304 ++E V R C + PVV VS+RV ++ G G G+DL EAGA+ L P QA Sbjct 231 PCIVEAV-RECTRRNIPVV--VSSRVPEGQLVPGYGGGGGGYDLGEAGAIHASTLRPGQA 287 Query 305 RVLLMAALAANS 316 R+LL A +A+ S Sbjct 288 RILLAALIASGS 299 >gi|317508617|ref|ZP_07966275.1| asparaginase [Segniliparus rugosus ATCC BAA-974] gi|316253084|gb|EFV12496.1| asparaginase [Segniliparus rugosus ATCC BAA-974] Length=323 Score = 180 bits (457), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 133/313 (43%), Positives = 168/313 (54%), Gaps = 26/313 (8%) Query 10 PIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPA 69 P+ +T+ITTGGTI++ + GV RP L+ ++ V +++ DSS L A Sbjct 20 PMKRIVTLITTGGTIASVSDEAGVRRPVLGARDLLGSAGHRGEVRVREVVCKDSSLLDFA 79 Query 70 DWDRIGAAV-QEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 D D+I V +EA GV + HGTDT+EETA+ LDL AG +PV +TGA L A P Sbjct 80 DLDQIRRTVSEEAADPATVGVAVAHGTDTMEETAMLLDLMAAGDKPVAITGAALPASDPE 139 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG 188 ADGP NLRDALA AD AR V+V F G L G HK +GG Sbjct 140 ADGPRNLRDALAFVADGEARGGEVVVCFAGERLAARGAHK---------------RHTGG 184 Query 189 VRLTRTKTRPYLGDLGAAVAP-------RVDIVAVYPGSDAVAMDACVAAGARAVVLEAL 241 + + + RP G A P RVDIV +YPG+D A+DA VAAGAR +VLE + Sbjct 185 LDVFGGRPRPDRGAPAAVKLPGRDIAGTRVDIVVMYPGADRTALDAYVAAGARGLVLETM 244 Query 242 GSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPP 301 G+G V+E V H R G V + +RV GA V Y G LVEAGAV+ L Sbjct 245 GNGGVPDLVVEAVAEHARAG---VAVVACSRVPGAPVTGAYSGGARLVEAGAVLAQELRA 301 Query 302 SQARVLLMAALAA 314 QARV L A LA+ Sbjct 302 PQARVQLAALLAS 314 >gi|332716529|ref|YP_004443995.1| L-asparaginase [Agrobacterium sp. H13-3] gi|325063214|gb|ADY66904.1| L-asparaginase [Agrobacterium sp. H13-3] Length=317 Score = 179 bits (455), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 130/313 (42%), Positives = 173/313 (56%), Gaps = 13/313 (4%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALDSSKLTPADWDR 73 + VI TGGTI++ G DG P+ G L+A + +++ ++ VDLMA DSS LT AD R Sbjct 10 VAVIATGGTIASRRGADGASTPSLSGEDLLALVPQINARLKPVDLMAKDSSSLTLADMQR 69 Query 74 IGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGP 132 I AV A GVV+ HGTD +EE++L + L +A ++PVV TGA +AD P ADGP Sbjct 70 ISDAVGVELNDPAVTGVVVLHGTDAMEESSLLVHLQHAITKPVVFTGAQFTADHPNADGP 129 Query 133 ANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLT 192 +NL A+ A D + GVL+SFGGR L GL+K++ F + + L Sbjct 130 SNLAAAIETALDQTNAERGVLLSFGGRCLPAWGLYKLSADAADAFRSARPAAHTAALELA 189 Query 193 RTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIE 252 L DL RVDIVA+YPG DA ++A + AGA +VL ALGSGNA + Sbjct 190 VP-----LADL------RVDIVAIYPGCDAAHIEASLQAGADGIVLAALGSGNANPGIAV 238 Query 253 GVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAAL 312 V+R G VV + G G GHDLV AGA+ L P QAR+LL A + Sbjct 239 AVKRCAERGVPVVVSSRVPEGLLVASYGGGGGGHDLVAAGAIHSSTLRPGQARILLAALI 298 Query 313 AANSPVADVIDRW 325 AANSP ++ + Sbjct 299 AANSPAEKIVSAF 311 >gi|319950010|ref|ZP_08023990.1| L-asparaginase [Dietzia cinnamea P4] gi|319436327|gb|EFV91467.1| L-asparaginase [Dietzia cinnamea P4] Length=370 Score = 176 bits (445), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 135/311 (44%), Positives = 166/311 (54%), Gaps = 14/311 (4%) Query 14 RLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLD-----MDSDIEVVDLMALD--SSKL 66 + + TTGGTI+ + P+G + A LD + ++I V LD SS Sbjct 15 HIVICTTGGTITASTTPEGAVVAGDSDPATAAMLDELRAVLPAEIRVSARAVLDADSSTF 74 Query 67 TPADWDRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSAD 125 PA+WD I + + GVV+THGTDTLEETA+ LDL +A RPV LTGA +AD Sbjct 75 GPAEWDLIVDTLADVLADPEVSGVVVTHGTDTLEETAIALDLHHADPRPVALTGAQRAAD 134 Query 126 APGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFT 185 P ADGPANL DA+ +AADP +RDLGVLV G +LQ G+ K D FA S Sbjct 135 HPEADGPANLLDAVLLAADPVSRDLGVLVVLGRAILQARGVRKWHTTDPVAFARNSPEHP 194 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 L RP L RVD+VA PGSDA A++ACVAAGAR +VLE GSGN Sbjct 195 VED--LPPELERPTLTGRARFTETRVDVVACPPGSDATALNACVAAGARGLVLEGSGSGN 252 Query 246 AGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPS 302 V + V R D D VV+A S+RV A Y G G +L G + L Sbjct 253 LPPLVADAVARLAEDRPDIVVVA-SSRVPRGEATATYGGRGGGAELAARGVLSAGYLRSG 311 Query 303 QARVLLMAALA 313 QARVLL A L+ Sbjct 312 QARVLLAALLS 322 >gi|335035712|ref|ZP_08529046.1| L-asparaginase [Agrobacterium sp. ATCC 31749] gi|333792893|gb|EGL64256.1| L-asparaginase [Agrobacterium sp. ATCC 31749] Length=308 Score = 167 bits (423), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 136/318 (43%), Positives = 180/318 (57%), Gaps = 21/318 (6%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALDSSKLTPADWDR 73 + VI TGGTI++ G DG P+ G L+A + +++ ++ VDLMA DSS LT AD Sbjct 1 MAVIATGGTIASRRGADGASTPSLSGEDLLALVPQVNARLKPVDLMAKDSSSLTLADMQS 60 Query 74 IGAAVQ-EAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGP 132 I AV E G+V+ HGTD +EE++L + L +A +PVV TGA +AD ADGP Sbjct 61 ISDAVGIELSDPAVAGIVVLHGTDAMEESSLLVHLQHALPKPVVFTGAQFTADHRQADGP 120 Query 133 ANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLT 192 ANL A+ A D + GVL+SFGGR L GL+K++ F R Sbjct 121 ANLARAIETALDQRNAEKGVLLSFGGRCLPAWGLYKLSADAADAF------------RSA 168 Query 193 RTKTRPYLGDLGAAVAP-RVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 R + + L A V RVDIVA++PG DA +DA +AAGA+ +VL ALGSGNA + Sbjct 169 RPQVQTATPKLAAPVTDIRVDIVAIHPGCDATHIDASLAAGAKGIVLAALGSGNANPLIA 228 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARVLL 308 E V+R C + V + VS+RV + A Y G GHDLV AGAV L P QAR+LL Sbjct 229 EAVKR-CAERR--VPVVVSSRVPEGLLVASYGGGGGGHDLVAAGAVHSSTLRPGQARILL 285 Query 309 MAALAANSPVADVIDRWG 326 A LA NS ++ +G Sbjct 286 AALLAGNSSAETIVSAFG 303 >gi|338821341|gb|EGP55310.1| L-asparaginase [Agrobacterium tumefaciens F2] Length=317 Score = 163 bits (413), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 131/313 (42%), Positives = 171/313 (55%), Gaps = 15/313 (4%) Query 17 VITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALDSSKLTPADWDRIG 75 VI TGGTI++ G DGV P+ G L+A + + + ++ VDLMA DSS LT AD RI Sbjct 12 VIATGGTIASRRGIDGVSTPSLSGEDLLALVPQISARLKPVDLMAKDSSSLTLADMQRIS 71 Query 76 AAV-QEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPAN 134 AV E GVV+ HGTD +EE++L + L +A ++PVV TGA +AD P ADGP+N Sbjct 72 DAVGVELSDPTVAGVVVLHGTDAMEESSLLVHLQHAITKPVVFTGAQFTADYPDADGPSN 131 Query 135 LRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLTRT 194 L A+ A D + GVL+SFGGR L GL+K++ F + + Sbjct 132 LARAIETALDQTNAERGVLLSFGGRCLPVWGLYKLSADAADAFRSARPAAPAATL----- 186 Query 195 KTRPYLGDLGAAVA-PRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIEG 253 +L A VA RVDIVA+YPG DA ++A + AGA +VL ALGSGNA + Sbjct 187 -------NLAAPVAGLRVDIVAIYPGCDAAHIEASLQAGADGIVLAALGSGNANPGIAVA 239 Query 254 VRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAALA 313 V+R VV + G G GHDLV AGAV L P QAR+LL A LA Sbjct 240 VKRCAERRVPVVVSSRVPEGLLVASYGGGGGGHDLVAAGAVHSSTLRPGQARILLAALLA 299 Query 314 ANSPVADVIDRWG 326 SP ++ +G Sbjct 300 NKSPAETIVSAFG 312 >gi|108805636|ref|YP_645573.1| asparaginase [Rubrobacter xylanophilus DSM 9941] gi|108766879|gb|ABG05761.1| asparaginase [Rubrobacter xylanophilus DSM 9941] Length=330 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 121/314 (39%), Positives = 162/314 (52%), Gaps = 13/314 (4%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDI---EVVDLMALDSSKLTP 68 + + +ITTGGTI+ P G + G L+A + +++ +V+L +DSS +TP Sbjct 3 LPEIALITTGGTIAARPLPSGEVVVADSGEELLASVPELAEVARVRLVELFRIDSSLMTP 62 Query 69 ADWDRIGAAVQEAFRGGA-DGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAP 127 D I V+ R + G V+ HGTDT+EE+A +DL YAG RPVV TGA +AD P Sbjct 63 QDMLEIARRVRALDRDESLAGFVVAHGTDTMEESAYLVDLLYAGERPVVFTGAQRNADDP 122 Query 128 GADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLG---- 183 DGP NL DA +AA P AR LG +V+ GR+ KV L F+ G Sbjct 123 APDGPGNLLDAARIAASPEARGLGAVVAMAGRIDAARDATKVHTTSLEAFSSLDRGKLGE 182 Query 184 FTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGS 243 G VR+ R++ RP AV PRV +V + G D + A G +VLEALG Sbjct 183 VADGAVRIFRSRPRPLNLSATDAVEPRVALVKLAAGMDGALLRAAREGGTAGIVLEALGL 242 Query 244 GNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGP--GHDLVEAGAVMVPRLPP 301 GNA V+ V C + PV++ +RV V YG G DL AGA+ L Sbjct 243 GNANPGVVREV-ELCTEAGLPVLVV--SRVPSGSVAPVYGDGGGSDLARAGALFGGSLIG 299 Query 302 SQARVLLMAALAAN 315 +AR+LLM ALAA Sbjct 300 QKARILLMVALAAR 313 >gi|152964029|ref|YP_001359813.1| asparaginase/glutaminase [Kineococcus radiotolerans SRS30216] gi|151358546|gb|ABS01549.1| Asparaginase/glutaminase [Kineococcus radiotolerans SRS30216] Length=320 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 110/240 (46%), Positives = 139/240 (58%), Gaps = 13/240 (5%) Query 10 PIMARLTVITTGGTISTTAGPDGVLRPTHCGATLI--AGLDMDSDIEVVDLMALDSSKLT 67 P+ + V+TTGGTI++T DGV RPT G L+ AG + + VV+ + +DSS LT Sbjct 6 PLAPLVVVVTTGGTIASTVDEDGVSRPTLGGDALLGTAGDEAGVRVRVVEALRVDSSTLT 65 Query 68 PADWDRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADA 126 A D + A V EA G GVV+ HGTD+LEETA LDL + RPVVLTG+ +AD Sbjct 66 LAQADLVRARVAEALADPGVAGVVVLHGTDSLEETAYLLDLHHDDPRPVVLTGSQRTADH 125 Query 127 PGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGF-T 185 P D PAN+R+AL VAAD AR GVLV+FGGRV G K DL FA Sbjct 126 PAPDAPANVREALRVAADGLARGQGVLVAFGGRVHAAAGTTKRHTTDLDAFAAPDRALPR 185 Query 186 SGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGN 245 +G + + P+ PRVD+VA +PG+D +DA GAR VVL+ LGSGN Sbjct 186 AGALTAVGSPDAPW---------PRVDVVAAHPGTDGALLDAARELGARGVVLQGLGSGN 236 >gi|15891159|ref|NP_356831.1| L-asparaginase [Agrobacterium tumefaciens str. C58] gi|15159510|gb|AAK89616.1| L-asparaginase [Agrobacterium tumefaciens str. C58] Length=317 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 127/298 (43%), Positives = 169/298 (57%), Gaps = 21/298 (7%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALDSSKLTPADWDR 73 + VI TGGTI++ G DG P+ G L+A + +++ ++ VDLMA DSS LT A+ R Sbjct 10 VAVIATGGTIASRRGADGASTPSLSGEDLLALVPQVNARLKPVDLMAKDSSSLTLANMQR 69 Query 74 IGAAV-QEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGP 132 I AV E G+V+ HGTD +EE++L + L +A +PVV TGA +AD ADGP Sbjct 70 ISDAVGIELSDPAVAGIVVLHGTDAMEESSLLVHLQHALPKPVVFTGAQFTADHRQADGP 129 Query 133 ANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLT 192 ANL A+ A D + GVL+SFGGR L GL+K++ F R Sbjct 130 ANLARAIETALDQRNAEKGVLLSFGGRCLPAWGLYKLSADAADAF------------RSA 177 Query 193 RTKTRPYLGDLGAAVAP-RVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 R + + L A V RVDIVA++PG DA +DA +AAGA+ +VL ALGSGNA + Sbjct 178 RPQVQAAAPKLAAPVTDIRVDIVAIHPGCDATHIDASLAAGAKGIVLAALGSGNANPLIA 237 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARV 306 E V+R C + V + VS+RV + A Y G GHDLV GAV L P QAR+ Sbjct 238 EAVKR-CAERR--VPVVVSSRVPEGLLVASYGGGGGGHDLVAVGAVHSSTLRPGQARI 292 >gi|227503299|ref|ZP_03933348.1| possible asparaginase [Corynebacterium accolens ATCC 49725] gi|227075802|gb|EEI13765.1| possible asparaginase [Corynebacterium accolens ATCC 49725] Length=304 Score = 160 bits (406), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 130/315 (42%), Positives = 163/315 (52%), Gaps = 27/315 (8%) Query 12 MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADW 71 M L +I TGGTI+ T DG L PT GA L A D D EVV+ LDSS +T AD Sbjct 1 MTNLALIATGGTIACTTVRDGSLVPTVTGAQLAA----DIDAEVVEFRQLDSSSITLADL 56 Query 72 DRIGAAVQEAF-RGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 D + A V E R DGV+ITHGTD++EETA+ L++ AG P+VLTGA S D P D Sbjct 57 DELIAVVNEQTARADIDGVIITHGTDSMEETAMALEIFCAGDTPIVLTGAQRSYDHPHPD 116 Query 131 GPANLRDA--LAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG 188 GP NLRDA LA++ P GV + FGG + G K DL F ESL Sbjct 117 GPRNLRDARELALSGQP-----GVFIRFGGMTIPARGARKQHTSDLRAF--ESLRIPDAT 169 Query 189 VRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGA 248 RL P+ V+I+ YPG+ V +DA + A +V+EA+G+GN Sbjct 170 PRLHPQPLAPH----------PVEIIPAYPGAGRVLVDAARTSAA-GLVIEAMGAGNMSG 218 Query 249 AVIEGVRRHCRDGSDPVVIAVSTRV-AGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVL 307 + + RDG PVVI+ T A A G G G L GA+ PSQAR+L Sbjct 219 DMGRALADALRDGL-PVVISTRTPYGATALSYGGDGGGASLHSLGAINAGAFRPSQARIL 277 Query 308 LMAALAANSPVADVI 322 L A LA + A+V Sbjct 278 LAAVLATGTDPAEVF 292 >gi|227504707|ref|ZP_03934756.1| L-asparaginase [Corynebacterium striatum ATCC 6940] gi|227198717|gb|EEI78765.1| L-asparaginase [Corynebacterium striatum ATCC 6940] Length=305 Score = 160 bits (404), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 129/315 (41%), Positives = 169/315 (54%), Gaps = 28/315 (8%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRI 74 + +I TGGTI+ T DG L PT G L LD +DIEV++ LDSS +T D D + Sbjct 3 IALIATGGTIACTTQEDGSLVPTVSGQQLADSLD--ADIEVIEFRQLDSSSITLEDLDEL 60 Query 75 GAAVQEAF-RGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPA 133 A V E R +G++ITHGTD++EETA+ L + G++PVVLTGA S D P DGP Sbjct 61 LATVHELLHRAEVEGILITHGTDSMEETAMALSIFDPGTKPVVLTGAQRSFDHPNGDGPR 120 Query 134 NLRDALAV--AADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRL 191 NL+DA+A+ A P GV + FGG + G K L GF ES+ G + Sbjct 121 NLQDAVALIKQAQP-----GVFIQFGGMTIPARGARKNHTFHLNGF--ESMPVGEGSI-- 171 Query 192 TRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVI 251 + L A V I+A YPG++AV +DA + A +V+E LGSGN GA + Sbjct 172 -------FPLPLAALAQHPVAILAAYPGAEAVLVDAASSHFA-GLVIEGLGSGNMGAGMG 223 Query 252 EGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARVLL 308 EGV R G + + VSTRV + Y G G L + GAV P QAR+LL Sbjct 224 EGVARALDAG---ISVVVSTRVPYGKTSLAYGGAGGGATLADKGAVNAGEFRPGQARILL 280 Query 309 MAALAANSPVADVID 323 AALA +PV V + Sbjct 281 AAALATGTPVVKVFE 295 >gi|340029682|ref|ZP_08665745.1| asparaginase/glutaminase [Paracoccus sp. TRP] Length=331 Score = 159 bits (401), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 120/306 (40%), Positives = 170/306 (56%), Gaps = 24/306 (7%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLD-MDSDIEVVDLMALDSSKLTPADWDR 73 L V+TTGGTI+++ DG RP A L++ L M D+ +++A DS+ LT AD R Sbjct 18 LVVLTTGGTIASSLDSDGAARPNLGAAELLSLLPPMAVDLRAQEVLAKDSASLTLADMQR 77 Query 74 IGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGP 132 I AV A GV+ HGTD +EETAL + L + +PV+ TGA ++D P +DG Sbjct 78 ISDAVGAALADPQVTGVIALHGTDAMEETALLVQLQHGPQKPVIFTGAQFASDHPRSDGA 137 Query 133 ANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVAN--PDLCGFAGESLGFTSGGVR 190 N DA+ A P A D GV ++FGG+V+ GL+K + PD + G Sbjct 138 RNFTDAVRAALQPQA-DPGVALAFGGQVMPVWGLYKFSTDAPDAFRRVADE------GAT 190 Query 191 LTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAV 250 ++ P + DL RVDI+A +PGSD + ++A +AAGAR +V+ ALGSGNA + Sbjct 191 ISHPLPAP-VSDL------RVDIIAAHPGSDGLLLEASLAAGARGIVIAALGSGNATPEL 243 Query 251 IEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQARVL 307 + + R +G+ V+ VS+RV + Y G GHD+ AGA+ L P QAR+L Sbjct 244 VAAIARARNEGA---VVVVSSRVPEGLLSPIYGGGGGGHDMRRAGAIHARVLRPGQARIL 300 Query 308 LMAALA 313 L A LA Sbjct 301 LAAMLA 306 >gi|227833476|ref|YP_002835183.1| L-asparaginase [Corynebacterium aurimucosum ATCC 700975] gi|262184464|ref|ZP_06043885.1| L-asparaginase [Corynebacterium aurimucosum ATCC 700975] gi|227454492|gb|ACP33245.1| L-asparaginase [Corynebacterium aurimucosum ATCC 700975] Length=311 Score = 157 bits (398), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 133/317 (42%), Positives = 166/317 (53%), Gaps = 25/317 (7%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMD---SDIEVVDLMALDSSKLTPADW 71 +I TGGTI+ T DG L PT G L A L D DIEVV+ ALDSS +T AD Sbjct 3 FALIATGGTIACTTVRDGSLVPTVSGQQLAASLGADDGTHDIEVVEFRALDSSSITLADL 62 Query 72 DRIGAAVQEAF-RGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGAD 130 D + V+E R DGV+ITHGTD+LEETAL L L G P+VLTGA + D P D Sbjct 63 DELLLCVREQLARPDIDGVLITHGTDSLEETALALSLFDLGDGPIVLTGAQRAFDHPAGD 122 Query 131 GPANLRDALAV--AADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG 188 GP NLRDA + + P GV V FGG+ + G K L GF E L Sbjct 123 GPRNLRDAYELLRSGKP-----GVWVQFGGKTIPGRGARKWHTSQLNGF--EELPVGDSA 175 Query 189 VRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGA 248 V L P G+ V+I+A YPG+ A +DA + R +V+EA+GSGN GA Sbjct 176 VPL--LPLAPMAGN-------PVEIIAAYPGAGATLVDASLPH-TRGLVIEAMGSGNMGA 225 Query 249 AVIEGVRRHCRDGSDPVVIAVSTRVAGARVG-AGYGPGHDLVEAGAVMVPRLPPSQARVL 307 + GV R + PVVI+ T ++ G G G L E GAV QAR++ Sbjct 226 EMGAGVARALQ-ADIPVVISTRTPYGNTKLAYGGAGGGATLGEMGAVAAGGFRAGQARIM 284 Query 308 LMAALAANSPVADVIDR 324 L AALA +PVA++ R Sbjct 285 LAAALATGTPVAEMFSR 301 >gi|119386949|ref|YP_918004.1| asparaginase/glutaminase [Paracoccus denitrificans PD1222] gi|119377544|gb|ABL72308.1| asparaginase [Paracoccus denitrificans PD1222] Length=327 Score = 157 bits (398), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 126/317 (40%), Positives = 172/317 (55%), Gaps = 30/317 (9%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGL-DMDSDIEVVDLMALDSSKLTPADWDR 73 L V+ TGGTI+++ G DG P+ L+A L M D+ +++A DS+ LT AD R Sbjct 18 LAVLATGGTIASSRGADGAASPSLRAEDLLALLPSMAVDLRPQEVLAKDSASLTLADMQR 77 Query 74 IGAAVQEAFRGGAD----GVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGA 129 I AV AD G+V HGTD +EETAL + L +A +PVV TGA ++D P + Sbjct 78 ISDAVATEL---ADPRIAGIVALHGTDAMEETALLVQLQHAPRKPVVFTGAQFASDHPRS 134 Query 130 DGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVAN--PDLCGFAGESLGFTSG 187 DG NL DA+ A P R GV ++FGGRVL GL+K + PD + Sbjct 135 DGARNLTDAVRTALQP-PRPGGVTLAFGGRVLPVWGLYKFTSDAPDAFRRVADE------ 187 Query 188 GVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAG 247 G +TR P G RVDIVA +PGSD + ++A +AAGA+ +V+ ALGSGNA Sbjct 188 GATVTRPLPAPVDGL-------RVDIVATHPGSDGLHLEASLAAGAQGIVVSALGSGNAT 240 Query 248 AAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQA 304 ++ + R G V++ VS+RV + Y G GHD+ AGA+ L P QA Sbjct 241 PELVAAISRARAQG---VMVVVSSRVPEGLLSPIYGGGGGGHDMRRAGAIHARLLRPGQA 297 Query 305 RVLLMAALAANSPVADV 321 R+LL A LA A++ Sbjct 298 RILLAAMLANGCSEAEI 314 >gi|237785356|ref|YP_002906061.1| L-asparaginase [Corynebacterium kroppenstedtii DSM 44385] gi|237758268|gb|ACR17518.1| L-asparaginase [Corynebacterium kroppenstedtii DSM 44385] Length=333 Score = 156 bits (394), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 111/310 (36%), Positives = 162/310 (53%), Gaps = 21/310 (6%) Query 14 RLTVITTGGTISTTAGPDGVLRPTHCGATLI----AGLDMDSDIEVVDLMALDSSKLTPA 69 R+ V+ TGGTIS T G L PT L+ + + +E D+ LDSS +T Sbjct 28 RIVVLGTGGTISCTHDSSGALVPTLSTQQLVDPVVQRFEGNVIVEARDISQLDSSSITFD 87 Query 70 DWDRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 D+D I AA++E GVV+THGTD++EE+A+ D+ + SRPV+ TGA AD P Sbjct 88 DYDTINAAIKEVLSDPEVTGVVVTHGTDSMEESAIAADIVHNDSRPVIFTGAQRPADHPE 147 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGG 188 ADGP NL +++ +A D +ARD+GVL+ FG V+ G K D FA T+ Sbjct 148 ADGPGNLFESIVIATDNSARDIGVLIVFGHAVIPARGAVKWHTSDPLAFA------TNAP 201 Query 189 VRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGA 248 R + P + G RVDI+ YPG+DA ++A + AG +V+E +G+GN G Sbjct 202 DEPPRPRPLPKVTFAGH----RVDIIPAYPGADATLLNAAIDAGTEGLVIEGMGAGNVGD 257 Query 249 AVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGY---GPGHDLVEAGAVMVPRLPPSQAR 305 A+ + + G + I +++RV V Y G G L G + + QAR Sbjct 258 ALATAITSALKQG---IPIVMASRVPRGNVNPLYGGDGGGLTLSRQGVIGAGCVHAGQAR 314 Query 306 VLLMAALAAN 315 ++L AA+ A Sbjct 315 IILAAAIDAE 324 >gi|296393821|ref|YP_003658705.1| asparaginase/glutaminase [Segniliparus rotundus DSM 44985] gi|296180968|gb|ADG97874.1| Asparaginase/glutaminase [Segniliparus rotundus DSM 44985] Length=301 Score = 154 bits (390), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 123/303 (41%), Positives = 159/303 (53%), Gaps = 14/303 (4%) Query 15 LTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRI 74 +T+ITTGGTI++ A P GV RP L+A ++V + + DSS L AD D+I Sbjct 5 VTLITTGGTIASVADPSGVRRPVLGAHDLLAATGYQGRVKVREAVRKDSSLLDFADVDQI 64 Query 75 GAAV-QEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPA 133 V QE GVV+ HGTDT+EETA+ LDL G +PVVLTGA A P DGPA Sbjct 65 RRIVAQELDNPSVSGVVVAHGTDTMEETAILLDLLTGGDKPVVLTGAARPASDPATDGPA 124 Query 134 NLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLTR 193 NLR ALA AA P AR G ++ F G L G HK F G + + V+ Sbjct 125 NLRHALAFAASPGARGAGAVICFAGATLAARGAHKRHTGGDDVFGGRAHAKGAPAVKAPA 184 Query 194 TKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIEG 253 A RVD+VA+ G+D +DA VAAGAR +VL +G+G +V + Sbjct 185 CDI----------AATRVDLVALCQGADRTGVDASVAAGARGLVLATMGNGGVPDSVTQA 234 Query 254 VRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAALA 313 V H R G + + +RV GA V Y G L+ AGA++ L QAR+ L A LA Sbjct 235 VAEHARAG---IAVVACSRVLGAPVTPEYSGGARLIAAGALLAAELSAPQARMQLAAVLA 291 Query 314 ANS 316 + S Sbjct 292 SGS 294 >gi|62290811|ref|YP_222604.1| L-asparaginase type II [Brucella abortus bv. 1 str. 9-941] gi|82700721|ref|YP_415295.1| asparaginase/glutaminase [Brucella melitensis biovar Abortus 2308] gi|148559011|ref|YP_001259779.1| putative L-asparaginase type II [Brucella ovis ATCC 25840] 43 more sequence titles Length=332 Score = 153 bits (387), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 111/310 (36%), Positives = 161/310 (52%), Gaps = 15/310 (4%) Query 14 RLTVITTGGTISTTAGPD-GVLRPTHCGATLIAGLDMDS---DIEVVDLMALDSSKLTPA 69 R+ +++TGGTI++ P L G L++ L + D+ + + L S+++ Sbjct 10 RILIVSTGGTIASRYDPQTDSLLSVSTGKELLSSLGALAPAVDVVLDEFCNLGSNRIDLD 69 Query 70 DWDRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 R+ + E R DG V+THGTDTLEE+A LT + +PVV TGA SAD P Sbjct 70 TSFRLAHHIDERLRDRTVDGCVVTHGTDTLEESAFLAQLTISSRKPVVFTGAQRSADEPD 129 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLG----F 184 ADGP NL DA++VAA P ARDLG LV F G+VL + K+ L + G Sbjct 130 ADGPRNLADAISVAASPEARDLGTLVVFAGKVLSSIDATKIHTSKLEAYDAPGYGPLGVV 189 Query 185 TSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSG 244 G V +TR K Y ++ RVD++ + G+D ++A + +G +LE G G Sbjct 190 DHGAVFITR-KPLGYPMIAAHSIETRVDLITLAMGADGRLIEAAINSGTHGFILETFGRG 248 Query 245 NAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGP--GHDLVEAGAVMVPRLPPS 302 NA AV++ V R G +V +++R RV YG G DL +AGA+ RL Sbjct 249 NATPAVVDAVARATERG---IVTIITSRCPDGRVLPVYGDGGGSDLEKAGAIFAGRLNGP 305 Query 303 QARVLLMAAL 312 +AR+LL +L Sbjct 306 KARILLCLSL 315 >gi|337290034|ref|YP_004629055.1| L-asparaginase [Corynebacterium ulcerans BR-AD22] gi|334698340|gb|AEG83136.1| L-asparaginase [Corynebacterium ulcerans BR-AD22] Length=360 Score = 153 bits (387), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 116/322 (37%), Positives = 165/322 (52%), Gaps = 29/322 (9%) Query 4 NHVRNDPIMARLTVITTGGTISTTAGPDGVLRPTHCGATLIA----GLDMDS-DIEVVDL 58 HV I L V++TGGTI++T DG L PT G L+A D IEV + Sbjct 44 KHVDYSAISGHLVVLSTGGTIAST-NVDGALVPTVSGEELVAPVYKKFSKDKLTIEVRQV 102 Query 59 MALDSSKLTPADWDRIGAAVQEAFR-GGADGVVITHGTDTLEETALWLDLTYAGSRPVVL 117 LDSS +T D D I V + + GV++THGTD++EE+A+ +D +G +PVV Sbjct 103 SQLDSSAMTLKDTDNIIREVLKTVKEDNVTGVIVTHGTDSMEESAIAVDTFLSGDKPVVF 162 Query 118 TGAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGF 177 TG+ML D P DGP NL A+ A DP + G ++FGG +++ G +K + GF Sbjct 163 TGSMLPFDDPHTDGPDNLTLAVTAATDPKNQGKGTFIAFGGTLIRARGAYKSHTSEKDGF 222 Query 178 ---AGESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGAR 234 AGE L RP D + RVDI+A YPG+ +DA ++ GA+ Sbjct 223 RTNAGEDL-------------VRPKPLDFKPLESYRVDIIAAYPGAPRALVDAAISTGAQ 269 Query 235 AVVLEALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARV---GAGYGPGHDLVEA 291 A+V+E +G+GN G + EG+ + I ++TRV V G G G L + Sbjct 270 ALVIEGMGAGNVGGDIAEGIVAAAEKN---IPIVMTTRVDAGLVEGTYGGAGGGATLAQK 326 Query 292 GAVMVPRLPPSQARVLLMAALA 313 G + L Q+R++L AALA Sbjct 327 GVIGSNYLRAGQSRIVLAAALA 348 >gi|261221012|ref|ZP_05935293.1| asparaginase/glutaminase [Brucella ceti B1/94] gi|265996972|ref|ZP_06109529.1| asparaginase/glutaminase [Brucella ceti M490/95/1] gi|260919596|gb|EEX86249.1| asparaginase/glutaminase [Brucella ceti B1/94] gi|262551440|gb|EEZ07430.1| asparaginase/glutaminase [Brucella ceti M490/95/1] Length=332 Score = 153 bits (386), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 111/310 (36%), Positives = 161/310 (52%), Gaps = 15/310 (4%) Query 14 RLTVITTGGTISTTAGPD-GVLRPTHCGATLIAGLDMDS---DIEVVDLMALDSSKLTPA 69 R+ +++TGGTI++ P L G L++ L + D+ + + L S+++ Sbjct 10 RILIVSTGGTIASRYDPQTDSLLSVSTGKELLSSLGALAPAVDVVLDEFCNLGSNRIDLD 69 Query 70 DWDRIGAAVQEAFRG-GADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPG 128 R+ + E R DG V+THGTDTLEE+A LT + +PVV TGA SAD P Sbjct 70 TSFRLAHHIDERLRDRTVDGCVVTHGTDTLEESAFLAQLTISSRKPVVFTGAQRSADEPD 129 Query 129 ADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLG----F 184 ADGP NL DA++VAA P ARDLG LV F G+VL + K+ L + G Sbjct 130 ADGPRNLADAISVAASPEARDLGTLVVFAGKVLSSIDATKIHTSKLEAYDAPGYGPLGVV 189 Query 185 TSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSG 244 G V +TR K Y ++ RVD++ + G+D ++A + +G +LE G G Sbjct 190 DHGAVFITR-KPLGYPMIAAHSIETRVDLITLAMGADGRLIEAAINSGTHGFILETFGRG 248 Query 245 NAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGP--GHDLVEAGAVMVPRLPPS 302 NA AV++ V R G +V +++R RV YG G DL +AGA+ RL Sbjct 249 NATPAVVDAVARATERG---IVTIITSRCPDGRVLPVYGDGGGSDLEKAGAIFAGRLNGP 305 Query 303 QARVLLMAAL 312 +AR+LL +L Sbjct 306 KARILLCLSL 315 Lambda K H 0.319 0.136 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 580252432782 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40