BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1540 Length=308 Score E Sequences producing significant alignments: (Bits) Value gi|15608678|ref|NP_216056.1| hypothetical protein Rv1540 [Mycoba... 619 3e-175 gi|298525052|ref|ZP_07012461.1| conserved hypothetical protein [... 617 9e-175 gi|167968095|ref|ZP_02550372.1| pseudouridylate synthase [Mycoba... 609 2e-172 gi|254550560|ref|ZP_05141007.1| hypothetical protein Mtube_08877... 590 8e-167 gi|342860878|ref|ZP_08717528.1| hypothetical protein MCOL_18443 ... 565 3e-159 gi|296164416|ref|ZP_06846990.1| RluA family RNA pseudouridine sy... 565 4e-159 gi|240167932|ref|ZP_04746591.1| RluA family pseudouridine syntha... 559 2e-157 gi|254821467|ref|ZP_05226468.1| hypothetical protein MintA_16155... 556 2e-156 gi|15827611|ref|NP_301874.1| pseudouridine synthase [Mycobacteri... 555 4e-156 gi|118617189|ref|YP_905521.1| RluA family pseudouridine synthase... 555 4e-156 gi|183982375|ref|YP_001850666.1| RluA family pseudouridine synth... 553 2e-155 gi|41407349|ref|NP_960185.1| hypothetical protein MAP1251 [Mycob... 552 2e-155 gi|254775679|ref|ZP_05217195.1| hypothetical protein MaviaA2_135... 545 2e-153 gi|118471435|ref|YP_887490.1| ribosomal large subunit pseudourid... 529 2e-148 gi|108800058|ref|YP_640255.1| ribosomal large subunit pseudourid... 529 2e-148 gi|118463205|ref|YP_882412.1| ribosomal large subunit pseudourid... 529 3e-148 gi|126435691|ref|YP_001071382.1| ribosomal large subunit pseudou... 528 3e-148 gi|333990824|ref|YP_004523438.1| RluA family pseudouridine synth... 523 1e-146 gi|145224223|ref|YP_001134901.1| RluA family pseudouridine synth... 522 3e-146 gi|120403758|ref|YP_953587.1| RluA family pseudouridine synthase... 519 2e-145 gi|312140126|ref|YP_004007462.1| tRNA-pseudouridine synthase i [... 492 4e-137 gi|325674393|ref|ZP_08154081.1| RluA family RNA pseudouridine sy... 488 4e-136 gi|226360214|ref|YP_002777992.1| pseudouridine synthase RluD [Rh... 488 7e-136 gi|229490347|ref|ZP_04384188.1| pseudouridine synthase, RluA fam... 485 4e-135 gi|111018085|ref|YP_701057.1| pseudouridylate synthase [Rhodococ... 484 5e-135 gi|226307021|ref|YP_002766981.1| pseudouridine synthase RluD [Rh... 483 1e-134 gi|169629784|ref|YP_001703433.1| pseudouridine synthase RluD [My... 476 2e-132 gi|54023755|ref|YP_117997.1| putative RNA pseudouridine synthase... 475 3e-132 gi|296140324|ref|YP_003647567.1| pseudouridine synthase [Tsukamu... 474 1e-131 gi|333919042|ref|YP_004492623.1| Pseudouridine synthase [Amycoli... 466 2e-129 gi|326382577|ref|ZP_08204268.1| pseudouridine synthase, RluA fam... 459 3e-127 gi|262202888|ref|YP_003274096.1| pseudouridine synthase [Gordoni... 452 2e-125 gi|343924230|ref|ZP_08763793.1| pseudouridine synthase RluD [Gor... 442 3e-122 gi|19553337|ref|NP_601339.1| 23S RNA-specific pseudouridylate sy... 433 2e-119 gi|324999316|ref|ZP_08120428.1| ribosomal large subunit pseudour... 429 2e-118 gi|134102271|ref|YP_001107932.1| ribosomal large subunit pseudou... 426 2e-117 gi|331696640|ref|YP_004332879.1| RluA family pseudouridine synth... 426 2e-117 gi|225021946|ref|ZP_03711138.1| hypothetical protein CORMATOL_01... 426 2e-117 gi|256379746|ref|YP_003103406.1| RluA family pseudouridine synth... 425 4e-117 gi|213965290|ref|ZP_03393487.1| ribosomal large subunit pseudour... 422 3e-116 gi|25028588|ref|NP_738642.1| putative ribosomal large subunit ps... 422 4e-116 gi|302206504|gb|ADL10846.1| Ribosomal large subunit pseudouridin... 419 2e-115 gi|300858799|ref|YP_003783782.1| hypothetical protein cpfrc_0138... 419 3e-115 gi|300784875|ref|YP_003765166.1| ribosomal large subunit pseudou... 418 6e-115 gi|257056703|ref|YP_003134535.1| ribosomal large subunit pseudou... 417 1e-114 gi|38234158|ref|NP_939925.1| putative pseudouridine synthase [Co... 417 1e-114 gi|337291104|ref|YP_004630125.1| hypothetical protein CULC22_014... 416 2e-114 gi|319949599|ref|ZP_08023642.1| pseudouridine synthase, RluA fam... 415 5e-114 gi|334564624|ref|ZP_08517615.1| pseudouridylate synthase [Coryne... 415 6e-114 gi|317508658|ref|ZP_07966314.1| RluA family pseudouridine syntha... 415 6e-114 >gi|15608678|ref|NP_216056.1| hypothetical protein Rv1540 [Mycobacterium tuberculosis H37Rv] gi|15841007|ref|NP_336044.1| pseudouridine synthase, RluD-related protein [Mycobacterium tuberculosis CDC1551] gi|31792726|ref|NP_855219.1| hypothetical protein Mb1567 [Mycobacterium bovis AF2122/97] 59 more sequence titles Length=308 Score = 619 bits (1595), Expect = 3e-175, Method: Compositional matrix adjust. Identities = 308/308 (100%), Positives = 308/308 (100%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL Sbjct 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD Sbjct 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA Sbjct 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 Query 301 LKILRGEG 308 LKILRGEG Sbjct 301 LKILRGEG 308 >gi|298525052|ref|ZP_07012461.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298494846|gb|EFI30140.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=308 Score = 617 bits (1590), Expect = 9e-175, Method: Compositional matrix adjust. Identities = 307/308 (99%), Positives = 307/308 (99%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL Sbjct 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPEAPAPLQNTPIDIEGM ILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 QVRLPEAPAPLQNTPIDIEGMKILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD Sbjct 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA Sbjct 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 Query 301 LKILRGEG 308 LKILRGEG Sbjct 301 LKILRGEG 308 >gi|167968095|ref|ZP_02550372.1| pseudouridylate synthase [Mycobacterium tuberculosis H37Ra] gi|294996507|ref|ZP_06802198.1| hypothetical protein Mtub2_18881 [Mycobacterium tuberculosis 210] gi|297731096|ref|ZP_06960214.1| hypothetical protein MtubKR_08397 [Mycobacterium tuberculosis KZN R506] 12 more sequence titles Length=303 Score = 609 bits (1570), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%), Gaps = 0/303 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP Sbjct 1 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT Sbjct 61 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT Sbjct 121 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH Sbjct 181 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR Sbjct 241 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 300 Query 306 GEG 308 GEG Sbjct 301 GEG 303 >gi|254550560|ref|ZP_05141007.1| hypothetical protein Mtube_08877 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|297634109|ref|ZP_06951889.1| hypothetical protein MtubK4_08307 [Mycobacterium tuberculosis KZN 4207] gi|339294515|gb|AEJ46626.1| pseudouridylate synthase [Mycobacterium tuberculosis CCDC5079] gi|339298151|gb|AEJ50261.1| pseudouridylate synthase [Mycobacterium tuberculosis CCDC5180] Length=294 Score = 590 bits (1521), Expect = 8e-167, Method: Compositional matrix adjust. Identities = 294/294 (100%), Positives = 294/294 (100%), Gaps = 0/294 (0%) Query 15 MRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLPEAPAPLQNT 74 MRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLPEAPAPLQNT Sbjct 1 MRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLPEAPAPLQNT 60 Query 75 PIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGVHERQGI 134 PIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGVHERQGI Sbjct 61 PIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGVHERQGI 120 Query 135 VHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGTIDAPIGRHR 194 VHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGTIDAPIGRHR Sbjct 121 VHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGTIDAPIGRHR 180 Query 195 GHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALHHPCCGDLVY 254 GHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALHHPCCGDLVY Sbjct 181 GHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALHHPCCGDLVY 240 Query 255 GADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILRGEG 308 GADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILRGEG Sbjct 241 GADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILRGEG 294 >gi|342860878|ref|ZP_08717528.1| hypothetical protein MCOL_18443 [Mycobacterium colombiense CECT 3035] gi|342131902|gb|EGT85159.1| hypothetical protein MCOL_18443 [Mycobacterium colombiense CECT 3035] Length=308 Score = 565 bits (1456), Expect = 3e-159, Method: Compositional matrix adjust. Identities = 277/308 (90%), Positives = 295/308 (96%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M+DRSMPVP+GLAGMRVD GLARLLGLSR+AAAA+AE+G VEL+GV AGKSDRL GA L Sbjct 1 MSDRSMPVPEGLAGMRVDAGLARLLGLSRSAAAAIAEDGGVELDGVQAGKSDRLTGGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPEAPAP QNTP+DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 QVRLPEAPAPPQNTPVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGV ERQGIVHRLDVGTSGVMVVA+SERAYT+LKRAFK RTVDKRYHALVQGHPD Sbjct 121 YRITTSGVPERQGIVHRLDVGTSGVMVVALSERAYTLLKRAFKQRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRG EWKFA+TK+GRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGGEWKFAVTKDGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+ALHHPCCGDLVYGADPKLAK+LGL+RQWLHARSL+FAHPADGRR+EIVSPYP DLQHA Sbjct 241 FSALHHPCCGDLVYGADPKLAKKLGLERQWLHARSLSFAHPADGRRIEIVSPYPPDLQHA 300 Query 301 LKILRGEG 308 L +LR EG Sbjct 301 LDVLRDEG 308 >gi|296164416|ref|ZP_06846990.1| RluA family RNA pseudouridine synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900198|gb|EFG79630.1| RluA family RNA pseudouridine synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=308 Score = 565 bits (1455), Expect = 4e-159, Method: Compositional matrix adjust. Identities = 276/308 (90%), Positives = 293/308 (96%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M DRSMPVP+GLAGMRVD GLARLLGLSR+AAAA+AE+G VEL+GV AGKSDRL GA L Sbjct 1 MTDRSMPVPEGLAGMRVDAGLARLLGLSRSAAAAIAEDGGVELDGVQAGKSDRLTGGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPEAP P++NTP+DIEGMTILYSD+DIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 QVRLPEAPPPVENTPVDIEGMTILYSDEDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGV ERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTVDKRYHALVQGHPD Sbjct 121 YRITTSGVPERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRG EWKFA+T NGRHSLTHYDT+EAF AASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGGEWKFAVTTNGRHSLTHYDTIEAFTAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+ALHHPCCGDLVYGADPKLAKRLGL+RQWLHARSL+FAHPADGRR+EIVSPYPADLQHA Sbjct 241 FSALHHPCCGDLVYGADPKLAKRLGLERQWLHARSLSFAHPADGRRMEIVSPYPADLQHA 300 Query 301 LKILRGEG 308 L +LR EG Sbjct 301 LDVLRAEG 308 >gi|240167932|ref|ZP_04746591.1| RluA family pseudouridine synthase [Mycobacterium kansasii ATCC 12478] Length=308 Score = 559 bits (1441), Expect = 2e-157, Method: Compositional matrix adjust. Identities = 273/308 (89%), Positives = 292/308 (95%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M DRSMPVP+GLAG+RVD GLARLLGLSR+A AA+AE G V+L+GVPAGKSDRL SGA L Sbjct 1 MPDRSMPVPEGLAGLRVDAGLARLLGLSRSAVAAIAEGGGVQLDGVPAGKSDRLTSGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPEAP PL+NTP+DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 QVRLPEAPPPLENTPVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGVHERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK+RTV+KRYHALVQGHPD Sbjct 121 YRITTSGVHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKHRTVEKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRH G EWKFA+T NGRHS+THYDT+EAFVAASLLD+ LETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHPGPEWKFAVTTNGRHSVTHYDTIEAFVAASLLDIELETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FAAL HPCCGDLVYGADPKLAK+LGL+RQWLHARSLAFAHPADGRR+EIVSPYP DLQHA Sbjct 241 FAALRHPCCGDLVYGADPKLAKKLGLERQWLHARSLAFAHPADGRRIEIVSPYPPDLQHA 300 Query 301 LKILRGEG 308 L +LR EG Sbjct 301 LDVLRAEG 308 >gi|254821467|ref|ZP_05226468.1| hypothetical protein MintA_16155 [Mycobacterium intracellulare ATCC 13950] Length=308 Score = 556 bits (1432), Expect = 2e-156, Method: Compositional matrix adjust. Identities = 279/308 (91%), Positives = 295/308 (96%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M+DRSMPVP+GLAGMRVD GLARLLGLSR+AAAALAE+G VEL+GV AGKSDRL GA L Sbjct 1 MSDRSMPVPEGLAGMRVDAGLARLLGLSRSAAAALAEDGGVELDGVQAGKSDRLTGGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRLPE PAPLQNTP+DIEGMTILYSDDDIVAVDKPAAVAAHASVGW+GPTVLGGLAAAG Sbjct 61 QVRLPEPPAPLQNTPVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWSGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGV ERQGIVHRLDVGTSGVMVVA+SERAYT+LKRAFK RTVDKRYHALVQGHPD Sbjct 121 YRITTSGVPERQGIVHRLDVGTSGVMVVALSERAYTLLKRAFKQRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRG EWKFAITK+GRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGGEWKFAITKDGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+ALHHPCCGDLVYGADPKLAKRLGL+RQWLHARSL+FAHPADGRR+EIVSPYP DLQHA Sbjct 241 FSALHHPCCGDLVYGADPKLAKRLGLERQWLHARSLSFAHPADGRRMEIVSPYPPDLQHA 300 Query 301 LKILRGEG 308 L +LR EG Sbjct 301 LDVLRDEG 308 >gi|15827611|ref|NP_301874.1| pseudouridine synthase [Mycobacterium leprae TN] gi|221230088|ref|YP_002503504.1| putative pseudouridine synthase [Mycobacterium leprae Br4923] gi|4539134|emb|CAB39580.1| putative pseudouridine synthase [Mycobacterium leprae] gi|13093162|emb|CAC31581.1| putative pseudouridine synthase [Mycobacterium leprae] gi|219933195|emb|CAR71295.1| putative pseudouridine synthase [Mycobacterium leprae Br4923] Length=308 Score = 555 bits (1430), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 274/307 (90%), Positives = 287/307 (94%), Gaps = 0/307 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M DRSMP+P+GLAGMRVD GLARLLGLSRTA AALAE+G VEL+GV AGKSDRL SGA L Sbjct 1 MTDRSMPIPEGLAGMRVDAGLARLLGLSRTAVAALAEDGGVELDGVQAGKSDRLTSGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 QVRL EAPAPL+NTP+DIE MTILYSDDDIVAVDKPAAVAAHASVGW GPTVLGGLAAAG Sbjct 61 QVRLCEAPAPLENTPVDIEDMTILYSDDDIVAVDKPAAVAAHASVGWAGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGV ERQGIVHRLDVGTSGVM+VAISERAYTVLKRAFK RTVDKRYHALVQGHPD Sbjct 121 YRITTSGVPERQGIVHRLDVGTSGVMLVAISERAYTVLKRAFKCRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGH WKFA+TK+GRHS+THYDTLEAFVAASLLDVHLETGRTHQIR H Sbjct 181 PSSGTIDAPIGRHRGHTWKFAVTKDGRHSITHYDTLEAFVAASLLDVHLETGRTHQIRAH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FA LH PCCGDLVYGADPKLAKRLGL+RQWLHARSL+FAHPADGRRVEIVS YP DLQHA Sbjct 241 FAELHRPCCGDLVYGADPKLAKRLGLERQWLHARSLSFAHPADGRRVEIVSSYPPDLQHA 300 Query 301 LKILRGE 307 L +LR E Sbjct 301 LDVLRAE 307 >gi|118617189|ref|YP_905521.1| RluA family pseudouridine synthase [Mycobacterium ulcerans Agy99] gi|118569299|gb|ABL04050.1| pseudouridine synthase, RluA-family [Mycobacterium ulcerans Agy99] Length=345 Score = 555 bits (1430), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 273/306 (90%), Positives = 287/306 (94%), Gaps = 0/306 (0%) Query 3 DRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQV 62 DRSMPVP+GLAGMRVD GLARLLGLSR+A A +AE G VEL+GVPAGKSDRL +GA L V Sbjct 4 DRSMPVPEGLAGMRVDAGLARLLGLSRSAVAVIAENGGVELDGVPAGKSDRLTAGAWLHV 63 Query 63 RLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYR 122 +LPEAP P +NTP++IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYR Sbjct 64 QLPEAPPPPENTPVEIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYR 123 Query 123 ITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPS 182 I+TSGVHERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTVDKRYHALVQGHPDPS Sbjct 124 ISTSGVHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVDKRYHALVQGHPDPS 183 Query 183 SGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFA 242 SGTIDAPIGRH G EWKFA+TKNGRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVHFA Sbjct 184 SGTIDAPIGRHPGGEWKFAVTKNGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVHFA 243 Query 243 ALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALK 302 ALHHPCCGDLVYGADPKLAKRLGL RQWLHARSLAFAHPADGRRVEIVSPYP DLQHAL Sbjct 244 ALHHPCCGDLVYGADPKLAKRLGLQRQWLHARSLAFAHPADGRRVEIVSPYPPDLQHALD 303 Query 303 ILRGEG 308 +L G Sbjct 304 VLPRRG 309 >gi|183982375|ref|YP_001850666.1| RluA family pseudouridine synthase [Mycobacterium marinum M] gi|183175701|gb|ACC40811.1| pseudouridine synthase, RluA-family [Mycobacterium marinum M] Length=303 Score = 553 bits (1424), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 272/303 (90%), Positives = 286/303 (95%), Gaps = 0/303 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVP+GLAGMRVD GLARLLGLSR+A A +AE G VEL+GVPAGKSDRL +GA L V+LP Sbjct 1 MPVPEGLAGMRVDAGLARLLGLSRSAVAVIAENGGVELDGVPAGKSDRLTAGAWLHVQLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAP P +NTP++IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI+T Sbjct 61 EAPPPPENTPVEIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRIST 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SGVHERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTVDKRYHALVQGHPDPSSGT Sbjct 121 SGVHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVDKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRH G EWKFA+TKNGRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVHFAALH Sbjct 181 IDAPIGRHPGGEWKFAVTKNGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVHFAALH 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDLVYGADPKLAKRLGL RQWLHARSLAFAHPADGRRVEIVSPYP DLQHAL +LR Sbjct 241 HPCCGDLVYGADPKLAKRLGLQRQWLHARSLAFAHPADGRRVEIVSPYPPDLQHALDVLR 300 Query 306 GEG 308 EG Sbjct 301 DEG 303 >gi|41407349|ref|NP_960185.1| hypothetical protein MAP1251 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395701|gb|AAS03568.1| hypothetical protein MAP_1251 [Mycobacterium avium subsp. paratuberculosis K-10] Length=308 Score = 552 bits (1423), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 277/308 (90%), Positives = 293/308 (96%), Gaps = 0/308 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M +RSMPVP+GLAGMRVD GLARLLGLSR+AAAALAE+G VEL+GVPAGKSDRL GA L Sbjct 1 MTERSMPVPEGLAGMRVDAGLARLLGLSRSAAAALAEDGGVELDGVPAGKSDRLTGGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 VRLPEAPAP QNTP+DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG Sbjct 61 HVRLPEAPAPPQNTPVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 YRITTSGV ERQGIVHRLDVGTSGVMVVA+SERAYT+LKRAFK RTVDKRYHALVQGHPD Sbjct 121 YRITTSGVPERQGIVHRLDVGTSGVMVVALSERAYTLLKRAFKQRTVDKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRG EWKFA+TK+GRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGGEWKFAVTKDGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+ALHHPCCGDLVYGADPKLAK+LGL RQWLHARSL+FAHPADGRR+EIVSPYP DLQHA Sbjct 241 FSALHHPCCGDLVYGADPKLAKKLGLQRQWLHARSLSFAHPADGRRMEIVSPYPPDLQHA 300 Query 301 LKILRGEG 308 L +LR EG Sbjct 301 LDVLRDEG 308 >gi|254775679|ref|ZP_05217195.1| hypothetical protein MaviaA2_13575 [Mycobacterium avium subsp. avium ATCC 25291] gi|336457945|gb|EGO36935.1| pseudouridine synthase, RluA family [Mycobacterium avium subsp. paratuberculosis S397] Length=303 Score = 545 bits (1405), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 274/303 (91%), Positives = 289/303 (96%), Gaps = 0/303 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVP+GLAGMRVD GLARLLGLSR+AAAALAE+G VEL+GVPAGKSDRL GA L VRLP Sbjct 1 MPVPEGLAGMRVDAGLARLLGLSRSAAAALAEDGGVELDGVPAGKSDRLTGGAWLHVRLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAPAP QNTP+DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT Sbjct 61 EAPAPPQNTPVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SGV ERQGIVHRLDVGTSGVMVVA+SERAYT+LKRAFK RTVDKRYHALVQGHPDPSSGT Sbjct 121 SGVPERQGIVHRLDVGTSGVMVVALSERAYTLLKRAFKQRTVDKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHRG EWKFA+TK+GRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVHF+ALH Sbjct 181 IDAPIGRHRGGEWKFAVTKDGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVHFSALH 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDLVYGADPKLAK+LGL RQWLHARSL+FAHPADGRR+EIVSPYP DLQHAL +LR Sbjct 241 HPCCGDLVYGADPKLAKKLGLQRQWLHARSLSFAHPADGRRMEIVSPYPPDLQHALDVLR 300 Query 306 GEG 308 EG Sbjct 301 DEG 303 >gi|118471435|ref|YP_887490.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium smegmatis str. MC2 155] gi|118172722|gb|ABK73618.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium smegmatis str. MC2 155] Length=309 Score = 529 bits (1363), Expect = 2e-148, Method: Compositional matrix adjust. Identities = 255/305 (84%), Positives = 279/305 (92%), Gaps = 0/305 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M RSMPVP+GLAGMRVD GL+RLLGLSRT A LAEEGAVEL+G PA KSD+LV+GA L Sbjct 1 MDTRSMPVPEGLAGMRVDAGLSRLLGLSRTVVATLAEEGAVELDGAPAAKSDKLVAGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 +VRLPEAP P++NTP+DIEGM ILYSD DIVAVDKP VAAHA+VGW GPTVLGGLAAAG Sbjct 61 EVRLPEAPKPVENTPVDIEGMNILYSDADIVAVDKPPGVAAHATVGWHGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 +RI+TSG+HERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTV+KRYHALVQGHPD Sbjct 121 FRISTSGIHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVEKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGH+WKFA+ + GRHS+THYDTLE F AASLLD+ LETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHDWKFAVVEGGRHSVTHYDTLEMFQAASLLDIELETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+ALHHPCCGDL YGADP LAKRLGL+RQWLHARSLAFAHPADGRRVEI SPYP DLQ+A Sbjct 241 FSALHHPCCGDLTYGADPTLAKRLGLERQWLHARSLAFAHPADGRRVEITSPYPDDLQNA 300 Query 301 LKILR 305 L +LR Sbjct 301 LDLLR 305 >gi|108800058|ref|YP_640255.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. MCS] gi|119869184|ref|YP_939136.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. KMS] gi|108770477|gb|ABG09199.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. MCS] gi|119695273|gb|ABL92346.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. KMS] Length=304 Score = 529 bits (1363), Expect = 2e-148, Method: Compositional matrix adjust. Identities = 252/300 (84%), Positives = 281/300 (94%), Gaps = 0/300 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVP+GL GMRVD GL+RLLGLSRTAAAA+AE+G V+++G PAGKSDRL +GA L+VRLP Sbjct 1 MPVPEGLGGMRVDAGLSRLLGLSRTAAAAIAEDGGVDIDGAPAGKSDRLTAGAWLEVRLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAP P++NTP++IEGM +LYSDDDIVAVDKP VAAHA+VGW GPTVLGGLAAAG+RI+T Sbjct 61 EAPPPVENTPVEIEGMAVLYSDDDIVAVDKPPGVAAHATVGWHGPTVLGGLAAAGFRIST 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SG+HERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTV+KRYHALVQGHPDPSSGT Sbjct 121 SGIHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVEKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHRGH+WKFA+T+ GRHS+THYDTLEAF AASLLD+ LETGRTHQIRVHFAALH Sbjct 181 IDAPIGRHRGHDWKFAVTEGGRHSVTHYDTLEAFQAASLLDIELETGRTHQIRVHFAALH 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDL YGADP LA+RLGL+RQWLHARSLAFAHPADGRR+EI SPYPADLQHAL +LR Sbjct 241 HPCCGDLTYGADPTLARRLGLERQWLHARSLAFAHPADGRRIEITSPYPADLQHALDVLR 300 >gi|118463205|ref|YP_882412.1| ribosomal large subunit pseudouridine synthase d [Mycobacterium avium 104] gi|118164492|gb|ABK65389.1| ribosomal large subunit pseudouridine synthase d [Mycobacterium avium 104] Length=294 Score = 529 bits (1362), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 266/294 (91%), Positives = 280/294 (96%), Gaps = 0/294 (0%) Query 15 MRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLPEAPAPLQNT 74 MRVD GLARLLGLSR+AAAALAE+G VEL+GVPAGKSDRL GA L VRLPEAPAP QNT Sbjct 1 MRVDAGLARLLGLSRSAAAALAEDGGVELDGVPAGKSDRLTGGAWLHVRLPEAPAPPQNT 60 Query 75 PIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGVHERQGI 134 P+DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGV ERQGI Sbjct 61 PVDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITTSGVPERQGI 120 Query 135 VHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGTIDAPIGRHR 194 VHRLDVGTSGVMVVA+SERAYT+LKRAFK RTVDKRYHALVQGHPDPSSGTIDAPIGRHR Sbjct 121 VHRLDVGTSGVMVVALSERAYTLLKRAFKQRTVDKRYHALVQGHPDPSSGTIDAPIGRHR 180 Query 195 GHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALHHPCCGDLVY 254 G EWKFA+TK+GRHSLTHYDT+EAFVAASLLDVHLETGRTHQIRVHF+ALHHPCCGDLVY Sbjct 181 GGEWKFAVTKDGRHSLTHYDTVEAFVAASLLDVHLETGRTHQIRVHFSALHHPCCGDLVY 240 Query 255 GADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILRGEG 308 GADPKLAK+LGL RQWLHARSL+FAHPADGRR+EIVSPYP DLQHAL +LR EG Sbjct 241 GADPKLAKKLGLQRQWLHARSLSFAHPADGRRMEIVSPYPPDLQHALDVLRDEG 294 >gi|126435691|ref|YP_001071382.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. JLS] gi|126235491|gb|ABN98891.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. JLS] Length=304 Score = 528 bits (1361), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 252/300 (84%), Positives = 281/300 (94%), Gaps = 0/300 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVP+GL GMRVD GL+RLLGLSRTAAAA+AE+G V+++G PAGKSDRL +GA L+VRLP Sbjct 1 MPVPEGLGGMRVDAGLSRLLGLSRTAAAAIAEDGRVDIDGAPAGKSDRLTAGAWLEVRLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAP P++NTP++IEGM +LYSDDDIVAVDKP VAAHA+VGW GPTVLGGLAAAG+RI+T Sbjct 61 EAPPPVENTPVEIEGMAVLYSDDDIVAVDKPPGVAAHATVGWHGPTVLGGLAAAGFRIST 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SG+HERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTV+KRYHALVQGHPDPSSGT Sbjct 121 SGIHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVEKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHRGH+WKFA+T+ GRHS+THYDTLEAF AASLLD+ LETGRTHQIRVHFAALH Sbjct 181 IDAPIGRHRGHDWKFAVTEGGRHSVTHYDTLEAFQAASLLDIELETGRTHQIRVHFAALH 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDL YGADP LA+RLGL+RQWLHARSLAFAHPADGRR+EI SPYPADLQHAL +LR Sbjct 241 HPCCGDLTYGADPTLARRLGLERQWLHARSLAFAHPADGRRIEITSPYPADLQHALDVLR 300 >gi|333990824|ref|YP_004523438.1| RluA family pseudouridine synthase [Mycobacterium sp. JDM601] gi|333486792|gb|AEF36184.1| RluA family pseudouridine synthase [Mycobacterium sp. JDM601] Length=301 Score = 523 bits (1347), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 257/300 (86%), Positives = 273/300 (91%), Gaps = 0/300 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVP+GLAGMRVD GLARLLGLSRT AA LAE G VEL+G PAGKSDRL +GA LQVRLP Sbjct 1 MPVPEGLAGMRVDAGLARLLGLSRTVAATLAENGDVELDGTPAGKSDRLAAGAWLQVRLP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 EAPAPL+NTP ++EGM ILYSD DIVAVDKPA VAAHASVGWTGPTVLGGLAAAGYRITT Sbjct 61 EAPAPLENTPAEVEGMAILYSDADIVAVDKPAGVAAHASVGWTGPTVLGGLAAAGYRITT 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SGV ERQGIVHRLDVGTSGVMVVAISERAYT LKRAFK RTV+KRYHALVQGHPDPSSGT Sbjct 121 SGVPERQGIVHRLDVGTSGVMVVAISERAYTALKRAFKARTVEKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRH G +WKF +T +GRHS+THYDTLEAFVAASLLDVHLETGRTHQIRVHFAAL Sbjct 181 IDAPIGRHHGRDWKFTVTADGRHSITHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALR 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDL YGADP LAK+LGL+RQWLHA SLAFAHP DGRR+EI S YPADL+HAL +LR Sbjct 241 HPCCGDLTYGADPTLAKKLGLERQWLHAHSLAFAHPGDGRRIEITSEYPADLRHALDVLR 300 >gi|145224223|ref|YP_001134901.1| RluA family pseudouridine synthase [Mycobacterium gilvum PYR-GCK] gi|315444557|ref|YP_004077436.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. Spyr1] gi|145216709|gb|ABP46113.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium gilvum PYR-GCK] gi|315262860|gb|ADT99601.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium sp. Spyr1] Length=309 Score = 522 bits (1345), Expect = 3e-146, Method: Compositional matrix adjust. Identities = 257/305 (85%), Positives = 282/305 (93%), Gaps = 0/305 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M RSMPVPDGLAGMRVD GLARLLGLSRTAAAA+AEEG V+++G PA KSD+LV+GA L Sbjct 1 MTTRSMPVPDGLAGMRVDAGLARLLGLSRTAAAAIAEEGGVDIDGAPAAKSDKLVAGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 +VRLP PAP++NTP+DIEGM ILYSDDDIVAVDKP VAAHA+VGW GPTVLGGLAAAG Sbjct 61 EVRLPPPPAPVENTPVDIEGMGILYSDDDIVAVDKPPGVAAHATVGWHGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 +RI+TSG+HERQGIVHRLDVGTSGVMVVA+SERAYTVLKRAFK RTV+KRYHALVQGHPD Sbjct 121 FRISTSGIHERQGIVHRLDVGTSGVMVVALSERAYTVLKRAFKQRTVEKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGH+WKFA+ ++GRHS+THYDTLEA AASLLD+ LETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHDWKFAVVEDGRHSITHYDTLEAHQAASLLDIELETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FAALHHPCCGDL YGADP LAK+LGL+RQWLHARSLAFAHPADGRRVE SPYPADLQHA Sbjct 241 FAALHHPCCGDLTYGADPTLAKKLGLERQWLHARSLAFAHPADGRRVEFTSPYPADLQHA 300 Query 301 LKILR 305 L +LR Sbjct 301 LDVLR 305 >gi|120403758|ref|YP_953587.1| RluA family pseudouridine synthase [Mycobacterium vanbaalenii PYR-1] gi|119956576|gb|ABM13581.1| ribosomal large subunit pseudouridine synthase D [Mycobacterium vanbaalenii PYR-1] Length=309 Score = 519 bits (1337), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 255/305 (84%), Positives = 280/305 (92%), Gaps = 0/305 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M RSMPVP+GLAGMRVD GLARLLGLSRTAAAA+AEEG VEL+G A KSD+L +GA L Sbjct 1 MTTRSMPVPEGLAGMRVDAGLARLLGLSRTAAAAIAEEGGVELDGARAAKSDKLTAGAWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 +VRLPEAPAP++NTP+DIEGM ILYSD+DIVAVDKP VAAHA+VGW GPTVLGGLAAAG Sbjct 61 EVRLPEAPAPVENTPVDIEGMGILYSDEDIVAVDKPPGVAAHATVGWHGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 +RI+TSG+HERQGIVHRLDVGTSGVMVVA+SERAYT LKRAFK RTV+KRYHALVQGHPD Sbjct 121 FRISTSGIHERQGIVHRLDVGTSGVMVVALSERAYTALKRAFKQRTVEKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGH+WKFA+ + GRHS+THYDTLEA AASLLD+ LETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHDWKFAVVEGGRHSVTHYDTLEAHQAASLLDIELETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 FAALHHPCCGDL YGADP LAK+LGL+RQWLHARSLAF HPADGRR+EI SPYPADLQHA Sbjct 241 FAALHHPCCGDLTYGADPTLAKKLGLERQWLHARSLAFVHPADGRRIEITSPYPADLQHA 300 Query 301 LKILR 305 L +LR Sbjct 301 LDVLR 305 >gi|312140126|ref|YP_004007462.1| tRNA-pseudouridine synthase i [Rhodococcus equi 103S] gi|311889465|emb|CBH48782.1| tRNA-pseudouridine synthase I [Rhodococcus equi 103S] Length=308 Score = 492 bits (1266), Expect = 4e-137, Method: Compositional matrix adjust. Identities = 241/303 (80%), Positives = 264/303 (88%), Gaps = 0/303 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL GMRVD GLARLLGLSRTA A L EEGAV ++G AGKSDRL +G L+V Sbjct 5 RSMPVPDGLDGMRVDAGLARLLGLSRTAVATLTEEGAVLVDGAAAGKSDRLSAGTWLEVE 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE P PL +EGM ILY+DDDIVAVDKP VAAHASVGWTGPTV+GGLAAAG+RI Sbjct 65 LPEPPRPLTIEAEPVEGMEILYADDDIVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA SERAYTVLKRAFK RT+DKRYHALVQGHPDPSS Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVATSERAYTVLKRAFKQRTIDKRYHALVQGHPDPSS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRHR ++WKFA+T +G+ S+THYDT+EAF AASLLD+HLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHRSNDWKFAVTADGKPSVTHYDTVEAFQAASLLDIHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPCCGDL YGADP+LA+RLGL+RQWLHARSL FAHPADG VEI S YP DLQHAL + Sbjct 245 LRHPCCGDLTYGADPRLAERLGLERQWLHARSLGFAHPADGHWVEITSDYPKDLQHALGV 304 Query 304 LRG 306 LRG Sbjct 305 LRG 307 >gi|325674393|ref|ZP_08154081.1| RluA family RNA pseudouridine synthase [Rhodococcus equi ATCC 33707] gi|325554653|gb|EGD24327.1| RluA family RNA pseudouridine synthase [Rhodococcus equi ATCC 33707] Length=302 Score = 488 bits (1257), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 239/301 (80%), Positives = 262/301 (88%), Gaps = 0/301 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVPDGL GMRVD GLARLLGLSRTA A L EEGAV ++G AGKSDRL +G L+V LP Sbjct 1 MPVPDGLDGMRVDAGLARLLGLSRTAVATLTEEGAVLVDGAAAGKSDRLSAGTWLEVELP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 E P PL +EGM ILY+DDDIVAVDKP VAAHASVGWTGPTV+GGLAAAG+RI+T Sbjct 61 EPPRPLTIEAEPVEGMEILYADDDIVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRIST 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SG HERQGIVHRLDVGTSGVMVVA SERAYTVLKRAFK RT+DKRYHALVQGHPDPSSGT Sbjct 121 SGAHERQGIVHRLDVGTSGVMVVATSERAYTVLKRAFKQRTIDKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHR ++WKFA+T +G+ S+THYDT+EAF AASLLD+HLETGRTHQIRVHF+AL Sbjct 181 IDAPIGRHRSNDWKFAVTADGKPSVTHYDTVEAFQAASLLDIHLETGRTHQIRVHFSALR 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDL YGADP+LA+RLGL+RQWLHARSL FAHPADG VEI S YP DLQHAL +LR Sbjct 241 HPCCGDLTYGADPRLAERLGLERQWLHARSLGFAHPADGHWVEITSDYPKDLQHALGVLR 300 Query 306 G 306 G Sbjct 301 G 301 >gi|226360214|ref|YP_002777992.1| pseudouridine synthase RluD [Rhodococcus opacus B4] gi|226238699|dbj|BAH49047.1| pseudouridine synthase RluD [Rhodococcus opacus B4] Length=308 Score = 488 bits (1255), Expect = 7e-136, Method: Compositional matrix adjust. Identities = 236/302 (79%), Positives = 262/302 (87%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL MRVD GLARLLGLSRTA A L EEG+V ++G P GKSDRL +G L+V Sbjct 5 RSMPVPDGLEAMRVDAGLARLLGLSRTAVAQLTEEGSVLVDGAPVGKSDRLSAGTWLEVE 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE P PL +EGM ILY+DDD+VAVDKP VAAHASVGWTGPTV+GGLAAAG+RI Sbjct 65 LPEPPRPLTIEAEPVEGMEILYADDDVVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA SERAYT+LKRAFK RT+DKRYHALVQGHPDPSS Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVATSERAYTLLKRAFKQRTIDKRYHALVQGHPDPSS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRHR ++WKFA+T +G+ S+THYDT+EAF AASLLD+HLETGRTHQIRVHFAA Sbjct 185 GTIDAPIGRHRSNDWKFAVTADGKPSITHYDTVEAFQAASLLDIHLETGRTHQIRVHFAA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPCCGDL YGADP+LA+RLGL+RQWLHARSL FAHPADGR VEI S YP DL+ AL + Sbjct 245 LRHPCCGDLTYGADPRLAERLGLERQWLHARSLGFAHPADGRWVEITSKYPKDLEDALGV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|229490347|ref|ZP_04384188.1| pseudouridine synthase, RluA family [Rhodococcus erythropolis SK121] gi|229322637|gb|EEN88417.1| pseudouridine synthase, RluA family [Rhodococcus erythropolis SK121] Length=308 Score = 485 bits (1248), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 235/302 (78%), Positives = 264/302 (88%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL MRVD GLARLLGLSRT AALAEEG+V ++GV GKSDRL +G+ L+V Sbjct 5 RSMPVPDGLDAMRVDAGLARLLGLSRTVVAALAEEGSVLVDGVAVGKSDRLTAGSWLEVV 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE P PL +EGM ILY+DDD+VAVDKP VAAHASVGWTGPTV+GGLAAAG+RI Sbjct 65 LPEPPRPLTIEATPVEGMEILYADDDVVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA SERAYT+LKRAFK RT+DKRYHALVQGHPDPSS Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVATSERAYTLLKRAFKQRTIDKRYHALVQGHPDPSS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH G++W+F +T +G+ S+THYDT+EAF AASLLDVHLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHHGNDWRFTVTADGKPSVTHYDTIEAFQAASLLDVHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPCCGDL YGADP+LA+RLGL+RQWLHA SL FAHPADGR VEI S YP DL+HAL++ Sbjct 245 LRHPCCGDLTYGADPRLAERLGLERQWLHAVSLGFAHPADGRWVEIKSKYPKDLEHALEV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|111018085|ref|YP_701057.1| pseudouridylate synthase [Rhodococcus jostii RHA1] gi|110817615|gb|ABG92899.1| pseudouridylate synthase [Rhodococcus jostii RHA1] Length=302 Score = 484 bits (1247), Expect = 5e-135, Method: Compositional matrix adjust. Identities = 235/300 (79%), Positives = 261/300 (87%), Gaps = 0/300 (0%) Query 6 MPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVRLP 65 MPVPDGL MRVD GLARLLGLSRTA A L EEG+V ++G P GKSDRL +GA L+V LP Sbjct 1 MPVPDGLEAMRVDAGLARLLGLSRTAVAQLTEEGSVLVDGAPVGKSDRLSAGAWLEVELP 60 Query 66 EAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRITT 125 E P PL +EGM ILY+DDD+VAVDKP VAAHASVGWTGPTV+GGLAAAG+RI+T Sbjct 61 EPPRPLTIEAEPVEGMEILYADDDVVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRIST 120 Query 126 SGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSSGT 185 SG HERQGIVHRLDVGTSGVMVVA SERAYT+LKRAFK RT+DKRYHALVQGHPDPSSGT Sbjct 121 SGAHERQGIVHRLDVGTSGVMVVATSERAYTLLKRAFKQRTIDKRYHALVQGHPDPSSGT 180 Query 186 IDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAALH 245 IDAPIGRHR ++WKFA+T +G+ S+THYDT+EAF AASLLD+HLETGRTHQIRVHFAAL Sbjct 181 IDAPIGRHRSNDWKFAVTADGKPSITHYDTVEAFQAASLLDIHLETGRTHQIRVHFAALR 240 Query 246 HPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKILR 305 HPCCGDL YGADP+LA+RLGL+RQWLHARSL FAHPADGR VEI S YP DL+ AL +LR Sbjct 241 HPCCGDLTYGADPRLAERLGLERQWLHARSLGFAHPADGRWVEITSKYPKDLEDALGVLR 300 >gi|226307021|ref|YP_002766981.1| pseudouridine synthase RluD [Rhodococcus erythropolis PR4] gi|226186138|dbj|BAH34242.1| putative pseudouridine synthase RluD [Rhodococcus erythropolis PR4] Length=308 Score = 483 bits (1244), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 234/302 (78%), Positives = 263/302 (88%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL MRVD GLARLLGLSRT A LAEEG+V ++GV GKSDRL +G+ L+V Sbjct 5 RSMPVPDGLDAMRVDAGLARLLGLSRTVVATLAEEGSVLVDGVAVGKSDRLTAGSWLEVV 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE P PL +EGM ILY+DDD+VAVDKP VAAHASVGWTGPTV+GGLAAAG+RI Sbjct 65 LPEPPRPLTIEATPVEGMEILYADDDVVAVDKPVGVAAHASVGWTGPTVIGGLAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA SERAYT+LKRAFK RT+DKRYHALVQGHPDPSS Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVATSERAYTLLKRAFKQRTIDKRYHALVQGHPDPSS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH G++W+F +T +G+ S+THYDT+EAF AASLLDVHLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHHGNDWRFTVTADGKPSVTHYDTIEAFQAASLLDVHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPCCGDL YGADP+LA+RLGL+RQWLHA SL FAHPADGR VEI S YP DL+HAL++ Sbjct 245 LRHPCCGDLTYGADPRLAERLGLERQWLHAVSLGFAHPADGRWVEIKSKYPKDLEHALEV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|169629784|ref|YP_001703433.1| pseudouridine synthase RluD [Mycobacterium abscessus ATCC 19977] gi|169241751|emb|CAM62779.1| Probable pseudouridine synthase RluD [Mycobacterium abscessus] Length=305 Score = 476 bits (1225), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 241/305 (80%), Positives = 270/305 (89%), Gaps = 0/305 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M RS+PVPDGL+GMRVD GLARLLGLSRTAAAALAEEGAV L+GV KS++L +G L Sbjct 1 MTSRSLPVPDGLSGMRVDAGLARLLGLSRTAAAALAEEGAVLLDGVAVTKSEKLTAGTWL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 +V LPE AP +N IEGM ILY+DDD+VAVDKPA VAAHASVGWTGPTVLGGLAAAG Sbjct 61 EVTLPEPKAPPENRVEVIEGMKILYADDDLVAVDKPAGVAAHASVGWTGPTVLGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 +R+TTSGV ER+GIVHRLDVGTSGVMVVA+SE+AYT LKRAFKYR V+KRYHALVQGHPD Sbjct 121 FRMTTSGVPERKGIVHRLDVGTSGVMVVALSEKAYTELKRAFKYRRVEKRYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PSSGTIDAPIGRHRGH+WKFA+ ++GRHS+THYDTLEAFVAASLLD+HLETGRTHQIRVH Sbjct 181 PSSGTIDAPIGRHRGHDWKFAVVEDGRHSITHYDTLEAFVAASLLDIHLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+A+ HPCCGDL YGADP LA +LGL+RQWLHA+SLAFAHP DGR +EI S YP DL HA Sbjct 241 FSAIKHPCCGDLTYGADPTLAAKLGLERQWLHAKSLAFAHPGDGRWIEITSEYPEDLAHA 300 Query 301 LKILR 305 L +LR Sbjct 301 LDVLR 305 >gi|54023755|ref|YP_117997.1| putative RNA pseudouridine synthase [Nocardia farcinica IFM 10152] gi|54015263|dbj|BAD56633.1| putative RNA pseudouridine synthase [Nocardia farcinica IFM 10152] Length=308 Score = 475 bits (1223), Expect = 3e-132, Method: Compositional matrix adjust. Identities = 232/302 (77%), Positives = 259/302 (86%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R+MPVPDGL GMRVD GL+RLLGLSRTA AAL EG+V+L+GVPAGKSDRL +GA L+V Sbjct 5 RAMPVPDGLDGMRVDAGLSRLLGLSRTAVAALTAEGSVQLDGVPAGKSDRLTAGAWLEVE 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 PE L +EGM ILY+DDDIVAVDKP VAAH VGW+GPTV+GGLAAAGYRI Sbjct 65 FPEPKRELTVEAAPVEGMKILYADDDIVAVDKPVGVAAHTGVGWSGPTVVGGLAAAGYRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA SE AYTVLKRAFK RTV KRYHALVQGHPDPSS Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVAQSEHAYTVLKRAFKQRTVSKRYHALVQGHPDPSS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGR RG++WKFA+T +GR S+THYDT+EAF AASLLD+HLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRARGNDWKFAVTADGRPSVTHYDTIEAFQAASLLDIHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 + HPCCGDL YGADP+LA+RLGL RQWLHAR+L F HPADGR +EI S YP DL+HAL + Sbjct 245 IRHPCCGDLTYGADPRLAERLGLQRQWLHARTLGFHHPADGRWLEITSEYPDDLRHALDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|296140324|ref|YP_003647567.1| pseudouridine synthase [Tsukamurella paurometabola DSM 20162] gi|296028458|gb|ADG79228.1| pseudouridine synthase, RluA family [Tsukamurella paurometabola DSM 20162] Length=308 Score = 474 bits (1219), Expect = 1e-131, Method: Compositional matrix adjust. Identities = 229/302 (76%), Positives = 255/302 (85%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R+MPVPDGL G+RVD G+ARLLGLSRT + LA EG+V L+G P GKSD+L +GALL V Sbjct 5 RTMPVPDGLDGLRVDAGVARLLGLSRTVVSELAAEGSVTLDGAPVGKSDKLRAGALLDVT 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PL+ + GM ILYSDDDIV VDKP VAAHASVGWTGPTV+GGLAAAG+RI Sbjct 65 LPEPARPLEIVAEPVPGMNILYSDDDIVVVDKPVGVAAHASVGWTGPTVIGGLAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ERQGIVHRLDVGTSGVM VA+SERAYTVLKRAFK RTVDKRYHALVQGHPDP S Sbjct 125 STSGAPERQGIVHRLDVGTSGVMAVAVSERAYTVLKRAFKQRTVDKRYHALVQGHPDPMS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRHR +WKFA+TK+G+ S+THYDT+EAF AA+LLDVHLETGRTHQIRVHFAA Sbjct 185 GTIDAPIGRHRSSDWKFAVTKDGKPSITHYDTIEAFQAATLLDVHLETGRTHQIRVHFAA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD YG+DP LAK+LGL+RQWLHAR+L F HP G VE SPYP DLQHAL + Sbjct 245 LHHPCCGDQTYGSDPVLAKKLGLERQWLHARTLGFTHPTKGEYVEFTSPYPDDLQHALDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|333919042|ref|YP_004492623.1| Pseudouridine synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333481263|gb|AEF39823.1| Pseudouridine synthase [Amycolicicoccus subflavus DQS3-9A1] Length=313 Score = 466 bits (1198), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 227/302 (76%), Positives = 258/302 (86%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL GMRVD GLARLLGLSRTA A L + G+V ++G AGKSDRL +GA L+V Sbjct 10 RSMPVPDGLEGMRVDAGLARLLGLSRTAVATLTDNGSVLVDGAVAGKSDRLHAGAWLEVE 69 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE +N P +EGMTIL++D DIVAVDKPA VAAHASVGWTGPTVLGGLAAAGYRI Sbjct 70 LPEPKREPENRPEPVEGMTILFADSDIVAVDKPAGVAAHASVGWTGPTVLGGLAAAGYRI 129 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ERQGIVHRLDVGTSGVM+VA+SERAY+++KRAFKYR V K+YH LVQGHPDPSS Sbjct 130 STSGPPERQGIVHRLDVGTSGVMLVAVSERAYSIMKRAFKYRNVKKQYHTLVQGHPDPSS 189 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTI+API RH ++WKFA+ +G+HS+THYDT+EAF AASLL V LETGRTHQIRVHF+A Sbjct 190 GTIEAPIARHGSNDWKFAVRADGKHSVTHYDTIEAFQAASLLSVDLETGRTHQIRVHFSA 249 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPCCGDL YGADP+LA+RLGL+RQWLHA SL FAHPADGR VEI S YPADL+HAL + Sbjct 250 LKHPCCGDLTYGADPRLAERLGLERQWLHACSLGFAHPADGRWVEITSEYPADLRHALDV 309 Query 304 LR 305 L Sbjct 310 LN 311 >gi|326382577|ref|ZP_08204268.1| pseudouridine synthase, RluA family protein [Gordonia neofelifaecis NRRL B-59395] gi|326198696|gb|EGD55879.1| pseudouridine synthase, RluA family protein [Gordonia neofelifaecis NRRL B-59395] Length=308 Score = 459 bits (1180), Expect = 3e-127, Method: Compositional matrix adjust. Identities = 221/302 (74%), Positives = 251/302 (84%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R+MPVPDGL GMRVD G+AR+LGLSRT A LA+ G + ++GV GKS +L +G+ L V Sbjct 5 RAMPVPDGLHGMRVDAGVARVLGLSRTVVATLADAGDITVDGVSVGKSHKLAAGSWLDVL 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PL P +E + ++Y D DI+ VDKPA VAAH S+GW+GPTV+G LAAAG+RI Sbjct 65 LPEPEQPLTVEPTPVEDLEVIYHDSDIIVVDKPAGVAAHPSLGWSGPTVIGALAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLD GTSGVMVVA SERAYT+LKRAFK RTVDKRYHALVQGH DP S Sbjct 125 STSGAHERQGIVHRLDAGTSGVMVVAASERAYTLLKRAFKQRTVDKRYHALVQGHLDPPS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH G +W+FA+T NGR S+THYDTLE F AASLLDVHLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHPGSDWRFAVTANGRESVTHYDTLEMFAAASLLDVHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 +HHPCCGD YGADPKLA RLGLDRQWLHAR+L FAHPADGRRVE + YPADLQHAL + Sbjct 245 MHHPCCGDPTYGADPKLAARLGLDRQWLHARTLGFAHPADGRRVEFTAEYPADLQHALDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|262202888|ref|YP_003274096.1| pseudouridine synthase [Gordonia bronchialis DSM 43247] gi|262086235|gb|ACY22203.1| pseudouridine synthase, RluA family [Gordonia bronchialis DSM 43247] Length=308 Score = 452 bits (1164), Expect = 2e-125, Method: Compositional matrix adjust. Identities = 221/302 (74%), Positives = 248/302 (83%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R +PVPDGL GMR+D LAR+LGLSRT A LA++G V ++GV GKS RL +GALL V Sbjct 5 RMLPVPDGLDGMRLDAALARMLGLSRTVVAGLADDGDVTVDGVAVGKSHRLAAGALLHVT 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PLQ P +E + ++Y D DI+ VDKP VAAH S+GW+GPTVLG L AAGYRI Sbjct 65 LPEPERPLQVEPTPVEDLDVIYHDSDIIVVDKPVGVAAHPSLGWSGPTVLGALDAAGYRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ERQGIV RLDVGTSGVMVVA+SERAY+VLKRAFK RTVDK YHALVQGH DP + Sbjct 125 STSGAPERQGIVSRLDVGTSGVMVVAVSERAYSVLKRAFKQRTVDKGYHALVQGHLDPPT 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH G +W+FA+T NG+ S+THY+TLE F AASLLD+HLETGRTHQIRVHFAA Sbjct 185 GTIDAPIGRHPGSDWRFAVTANGKPSITHYETLEMFAAASLLDIHLETGRTHQIRVHFAA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD YG DP LAKRLGLDRQWLHARSL FAHPADGRRVE SPYP DLQHAL + Sbjct 245 LHHPCCGDPTYGGDPVLAKRLGLDRQWLHARSLGFAHPADGRRVEFTSPYPHDLQHALDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|343924230|ref|ZP_08763793.1| pseudouridine synthase RluD [Gordonia alkanivorans NBRC 16433] gi|343766035|dbj|GAA10719.1| pseudouridine synthase RluD [Gordonia alkanivorans NBRC 16433] Length=308 Score = 442 bits (1137), Expect = 3e-122, Method: Compositional matrix adjust. Identities = 220/302 (73%), Positives = 251/302 (84%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R +PVPDGL GMRVD G++R+LGLSRT A LAEEG V ++GV GKS +L +G LL V Sbjct 5 RVVPVPDGLDGMRVDAGVSRMLGLSRTVVATLAEEGDVMVDGVVVGKSHKLAAGTLLHVT 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PL+ P +E + ++Y D DIV VDKP VAAH S+GW+GPTV+G LAAAG+RI Sbjct 65 LPEPDEPLRIEPTPVEDLEVIYHDSDIVVVDKPVGVAAHPSLGWSGPTVIGALAAAGFRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG HERQGIVHRLDVGTSGVMVVA+SERAYT+LKRAFK RTV K YHALVQGH DP S Sbjct 125 STSGAHERQGIVHRLDVGTSGVMVVAVSERAYTLLKRAFKQRTVHKGYHALVQGHLDPPS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRHRG++WKFA+T NG+ S+THYDTLE F AASL+DVHLETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHRGNDWKFAVTANGKPSITHYDTLEMFAAASLIDVHLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD YGADP LAK+LGL+RQWLHAR+L FAHPADGR VE S YP DLQHAL + Sbjct 245 LHHPCCGDPTYGADPVLAKKLGLERQWLHARTLRFAHPADGRTVEFSSEYPEDLQHALDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|19553337|ref|NP_601339.1| 23S RNA-specific pseudouridylate synthase [Corynebacterium glutamicum ATCC 13032] gi|62390974|ref|YP_226376.1| ribosomal large subunit pseudouridine synthase D [Corynebacterium glutamicum ATCC 13032] gi|145296099|ref|YP_001138920.1| hypothetical protein cgR_2020 [Corynebacterium glutamicum R] gi|21324908|dbj|BAB99531.1| Pseudouridylate synthases, 23S RNA-specific [Corynebacterium glutamicum ATCC 13032] gi|41326313|emb|CAF20475.1| RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE D [Corynebacterium glutamicum ATCC 13032] gi|140846019|dbj|BAF55018.1| hypothetical protein [Corynebacterium glutamicum R] gi|344044807|gb|EGV40482.1| hypothetical protein CgS9114_07861 [Corynebacterium glutamicum S9114] Length=310 Score = 433 bits (1113), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 208/304 (69%), Positives = 250/304 (83%), Gaps = 0/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R++PVP+GLAGMRVD L++LLG+SRT AA LA G V ++G GKS+RLV+ ++L V Sbjct 7 RTLPVPEGLAGMRVDAALSKLLGISRTVAAELATAGDVSVDGAVVGKSERLVADSMLDVL 66 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE APL + G+ ILYSDDD++AV+KP VAAH +VGW GPTV+GGLAAAG+RI Sbjct 67 LPEPAAPLMPKEEIVPGLDILYSDDDVIAVNKPVGVAAHPTVGWEGPTVVGGLAAAGFRI 126 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ER+GIV RLDVGTSGVMVVA SER YTVLKRAF+ RTVDK YHALVQGHPDP + Sbjct 127 STSGPPERKGIVQRLDVGTSGVMVVAASERGYTVLKRAFRDRTVDKTYHALVQGHPDPLT 186 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTI+APIGRH W+FA+T G+H++THY+TLEAF A+LL +HLETGRTHQIRVHF+A Sbjct 187 GTIEAPIGRHPSAGWRFAVTTEGKHAVTHYETLEAFQEATLLKIHLETGRTHQIRVHFSA 246 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD +YG+DP L++RLGL+RQWLHA SL F HPADGR +EIVSPYP DLQHAL + Sbjct 247 LHHPCCGDPMYGSDPALSERLGLNRQWLHAVSLGFNHPADGRWMEIVSPYPTDLQHALDV 306 Query 304 LRGE 307 LR + Sbjct 307 LREQ 310 >gi|324999316|ref|ZP_08120428.1| ribosomal large subunit pseudouridine synthase [Pseudonocardia sp. P1] Length=310 Score = 429 bits (1104), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 213/304 (71%), Positives = 247/304 (82%), Gaps = 2/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RSMPVPDGL GMR+D GL+RLLGLSRT A LAEEG ++++G AGKSDRL G+ L+V Sbjct 5 RSMPVPDGLDGMRIDAGLSRLLGLSRTVVAGLAEEGRIQVDGRDAGKSDRLPGGSWLEVE 64 Query 64 LPEAPAP--LQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 LP+A AP ++ + G+++L+ D+DIV VDKP VAAH S GWTGPTV GGLAA GY Sbjct 65 LPDAAAPAVIEGPAEVVAGLSVLHDDEDIVVVDKPVGVAAHPSPGWTGPTVTGGLAALGY 124 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 R++TSG ERQGIVHRLDVGT+GVMVVA SE AYT LKRAFK RTV+KRYHA+VQGHPDP Sbjct 125 RLSTSGAAERQGIVHRLDVGTTGVMVVATSEHAYTALKRAFKERTVEKRYHAVVQGHPDP 184 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 SSGTIDAPI RH H+++FA+ + G+ S+THYDT+EAF +ASLLDVHLETGRTHQIRVHF Sbjct 185 SSGTIDAPIDRHPRHDYRFAVLQGGKPSITHYDTIEAFRSASLLDVHLETGRTHQIRVHF 244 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +AL HPC GDL YGADP LAKR+GL RQWLHAR+L F HPADGR VE SPYP DL AL Sbjct 245 SALRHPCVGDLTYGADPTLAKRVGLSRQWLHARTLGFEHPADGRYVEFTSPYPDDLASAL 304 Query 302 KILR 305 LR Sbjct 305 AALR 308 >gi|134102271|ref|YP_001107932.1| ribosomal large subunit pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] gi|291003766|ref|ZP_06561739.1| ribosomal large subunit pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] gi|133914894|emb|CAM05007.1| ribosomal large subunit pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] Length=310 Score = 426 bits (1096), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 212/302 (71%), Positives = 242/302 (81%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R++PVPDGL GMRVD GL++LLGLSRT A LAE G V L+G PAGKSDRLV+GA L+V Sbjct 5 RTLPVPDGLDGMRVDAGLSKLLGLSRTIVAGLAESGDVVLDGTPAGKSDRLVAGAWLEVT 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LP A PL+ + +EG+ IL+ DDDIV VDKP VA H S GW GPTV+GGLAAAG RI Sbjct 65 LPPAEQPLEVVAVPVEGLRILHQDDDIVVVDKPIGVAVHPSPGWEGPTVVGGLAAAGVRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 TSG ERQG+VHRLD GT+GVMVVA SE AY+ LKRAFK RTVDKRYHALVQGHPDPS Sbjct 125 ATSGASERQGVVHRLDAGTTGVMVVAKSEHAYSTLKRAFKERTVDKRYHALVQGHPDPSR 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPI RH H++KFA+ G+ S+THY+T+EAF AASL+DV LETGRTHQIRVHFAA Sbjct 185 GTIDAPIDRHPRHDYKFAVVAGGKPSITHYETVEAFRAASLVDVKLETGRTHQIRVHFAA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 + HPC GDL YGADP LA+R+GL RQWLHARSL F HP+DGR V S YPADL HA+ + Sbjct 245 VRHPCVGDLTYGADPVLARRVGLSRQWLHARSLGFEHPSDGRWVSFDSDYPADLAHAVDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|331696640|ref|YP_004332879.1| RluA family pseudouridine synthase [Pseudonocardia dioxanivorans CB1190] gi|326951329|gb|AEA25026.1| pseudouridine synthase, RluA family [Pseudonocardia dioxanivorans CB1190] Length=312 Score = 426 bits (1096), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 215/305 (71%), Positives = 244/305 (80%), Gaps = 3/305 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVPDGL GMRVD GL+RLLGLSRT A LAEEG V ++G AGKSDRL +G L++ Sbjct 7 RSLPVPDGLDGMRVDAGLSRLLGLSRTVVATLAEEGRVAVDGRAAGKSDRLAAGGWLEIE 66 Query 64 LP--EAPAPLQNTPIDI-EGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 LP E + P+++ G+TIL+ DDDIV VDKP VAAH S GWTGPTV+GGLAA G Sbjct 67 LPDPERESDGITGPVEVVAGLTILHEDDDIVVVDKPVGVAAHPSPGWTGPTVVGGLAALG 126 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 R+ TSG ERQGIVHRLD GT+GVMVVA SE AY+ LKRAFK RTVDKRYHA+VQGHPD Sbjct 127 VRVATSGAAERQGIVHRLDAGTTGVMVVAKSESAYSELKRAFKERTVDKRYHAVVQGHPD 186 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 PS GTIDAPI RH H+W+FA+ + GR S+THYDT+EAF AASLLD+ LETGRTHQIRVH Sbjct 187 PSRGTIDAPIDRHPRHDWRFAVVEGGRPSVTHYDTIEAFRAASLLDIRLETGRTHQIRVH 246 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+A+ HPC GDL YGADP LAKRL LDRQWLHAR L FAHPADGRRVE SPYPADL A Sbjct 247 FSAMRHPCVGDLTYGADPTLAKRLHLDRQWLHARELGFAHPADGRRVEFTSPYPADLARA 306 Query 301 LKILR 305 L +L+ Sbjct 307 LDLLQ 311 >gi|225021946|ref|ZP_03711138.1| hypothetical protein CORMATOL_01978 [Corynebacterium matruchotii ATCC 33806] gi|305681500|ref|ZP_07404307.1| pseudouridine synthase, RluA family [Corynebacterium matruchotii ATCC 14266] gi|224945232|gb|EEG26441.1| hypothetical protein CORMATOL_01978 [Corynebacterium matruchotii ATCC 33806] gi|305659705|gb|EFM49205.1| pseudouridine synthase, RluA family [Corynebacterium matruchotii ATCC 14266] Length=310 Score = 426 bits (1096), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 208/304 (69%), Positives = 248/304 (82%), Gaps = 0/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLA MRVD L++L GLSRT +A LA +G V ++G PA KSD++ GA L+V Sbjct 6 RSLPVPEGLADMRVDVALSKLFGLSRTVSADLATKGDVLIDGKPATKSDKITDGAWLEVL 65 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PL T ++G+ ILY+D+D++AVDKP VAAH +VGW GPTV+GGLAAAGYRI Sbjct 66 LPEPQKPLVPTEELVDGLEILYADEDLIAVDKPVGVAAHPTVGWDGPTVVGGLAAAGYRI 125 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ER GIV RLDVGTSGVMVVA SER Y+VLKRAFK RTV K YHALVQGH DP + Sbjct 126 STSGPPERNGIVQRLDVGTSGVMVVAASERGYSVLKRAFKERTVSKTYHALVQGHMDPLA 185 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTI+A IGRH WKFA+T +G+H++THY+TLEAFVAASLL+VHLETGRTHQIRVH +A Sbjct 186 GTIEANIGRHPSSGWKFAVTSDGKHAVTHYETLEAFVAASLLEVHLETGRTHQIRVHMSA 245 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD +YGADP+L+ RLGL+RQWLHA L F HPADGR +EI SPYP DL+HAL++ Sbjct 246 LHHPCCGDPMYGADPQLSARLGLNRQWLHAVKLGFYHPADGRWLEIESPYPPDLRHALEV 305 Query 304 LRGE 307 LR E Sbjct 306 LRAE 309 >gi|256379746|ref|YP_003103406.1| RluA family pseudouridine synthase [Actinosynnema mirum DSM 43827] gi|255924049|gb|ACU39560.1| pseudouridine synthase, RluA family [Actinosynnema mirum DSM 43827] Length=310 Score = 425 bits (1093), Expect = 4e-117, Method: Compositional matrix adjust. Identities = 210/304 (70%), Positives = 243/304 (80%), Gaps = 0/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R++PVPDGL GMRVD GLA+LLGLSRT A+LAE G V L+G AGKSDRLV+G+ L++ Sbjct 6 RTLPVPDGLDGMRVDAGLAKLLGLSRTVIASLAESGDVVLDGRVAGKSDRLVAGSWLELT 65 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE P+Q + +EGM +L+ DDD++ VDKP VA H S GWTGPTV+GGLAAAG R+ Sbjct 66 LPEPERPVQVQAVPVEGMIVLHEDDDVIVVDKPVGVAVHPSPGWTGPTVVGGLAAAGVRV 125 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ERQG+VHRLDVGT+GVMVVA SE AY+VLK+AFK RTVDK YHALVQGHPDP Sbjct 126 STSGAAERQGVVHRLDVGTTGVMVVAKSEHAYSVLKQAFKDRTVDKLYHALVQGHPDPIK 185 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPI RH H++KFA+ G+ S+THY+ +EAF AASLLDVHLETGRTHQIRVHF+A Sbjct 186 GTIDAPIDRHPKHDYKFAVMAGGKPSITHYEVVEAFRAASLLDVHLETGRTHQIRVHFSA 245 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L HPC GDL Y ADP LAKRLG+ RQWLHAR L F HPADG VE S YP DL HALK+ Sbjct 246 LKHPCVGDLTYTADPVLAKRLGMSRQWLHARRLGFHHPADGEWVEFTSEYPDDLDHALKL 305 Query 304 LRGE 307 LR E Sbjct 306 LRSE 309 >gi|213965290|ref|ZP_03393487.1| ribosomal large subunit pseudouridine synthase D [Corynebacterium amycolatum SK46] gi|213952142|gb|EEB63527.1| ribosomal large subunit pseudouridine synthase D [Corynebacterium amycolatum SK46] Length=327 Score = 422 bits (1086), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 209/302 (70%), Positives = 240/302 (80%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R MPVP GLAGMRVD G+A+LLGLSRTA A LA G + ++GV GKSDRL A L V Sbjct 23 RQMPVPPGLAGMRVDAGVAKLLGLSRTAVADLAAAGDITVDGVSVGKSDRLEENAFLSVL 82 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LP PL +EGM +LY D D+VAV KP VAAH SVGW GPTV+GGLAAAG+RI Sbjct 83 LPPVEKPLVPKEELVEGMDVLYHDSDLVAVHKPVGVAAHPSVGWEGPTVIGGLAAAGFRI 142 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ER+GIVHRLDVGTSGVMVVA SER Y+VLKRAFK R V K YHALVQGHPDP S Sbjct 143 STSGPPERKGIVHRLDVGTSGVMVVACSERGYSVLKRAFKNREVSKTYHALVQGHPDPLS 202 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH W+FA+ ++G+H++THY+TLEAF A+LL V+LETGRTHQIRVHF+A Sbjct 203 GTIDAPIGRHPSAGWRFAVRQDGKHAVTHYETLEAFAPATLLKVNLETGRTHQIRVHFSA 262 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 L+HPCCGD +YG+DP LAKRLGL+RQWLHA SL F HPADGR +EI PYP DL HAL++ Sbjct 263 LNHPCCGDPMYGSDPALAKRLGLNRQWLHAVSLGFHHPADGRWMEIECPYPDDLNHALEV 322 Query 304 LR 305 LR Sbjct 323 LR 324 >gi|25028588|ref|NP_738642.1| putative ribosomal large subunit pseudouridine synthase [Corynebacterium efficiens YS-314] gi|259507644|ref|ZP_05750544.1| RluA family RNA pseudouridine synthase [Corynebacterium efficiens YS-314] gi|23493873|dbj|BAC18842.1| putative ribosomal large subunit pseudouridine synthase [Corynebacterium efficiens YS-314] gi|259164823|gb|EEW49377.1| RluA family RNA pseudouridine synthase [Corynebacterium efficiens YS-314] Length=309 Score = 422 bits (1085), Expect = 4e-116, Method: Compositional matrix adjust. Identities = 204/304 (68%), Positives = 247/304 (82%), Gaps = 0/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R++PVP+GLAGMRVD L++LLG+SRT AA LAE G V ++G KSDRLV+ ++L V Sbjct 6 RTLPVPEGLAGMRVDAALSKLLGISRTTAAELAEAGDVSVDGSAVRKSDRLVADSMLDVL 65 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 LPE PL + G+ ILY+DDD++AV+KP VAAH +VGW GPTV+GGLAAAG+RI Sbjct 66 LPEPAQPLVPREEIVPGLDILYADDDLIAVNKPVGVAAHPTVGWEGPTVVGGLAAAGFRI 125 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ER+GIV RLDVGTSGVMVVA SER YTVLKRAF+ RTV K YHALVQGHPDP+ Sbjct 126 STSGPPERKGIVQRLDVGTSGVMVVAASERGYTVLKRAFRDRTVQKTYHALVQGHPDPTE 185 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTI+APIGRH W+FA+T +G+H++THY+T+EAF A+L+ VHLETGRTHQIRVHF+A Sbjct 186 GTIEAPIGRHPSSGWRFAVTTDGKHAVTHYETIEAFQEATLVKVHLETGRTHQIRVHFSA 245 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPCCGD +YG+DP L++RLGL RQWLHA SL F HPADGR +EI SPYP DLQHAL + Sbjct 246 LHHPCCGDPMYGSDPALSERLGLIRQWLHAVSLGFHHPADGRWMEITSPYPDDLQHALDV 305 Query 304 LRGE 307 LR + Sbjct 306 LRDQ 309 >gi|302206504|gb|ADL10846.1| Ribosomal large subunit pseudouridine synthase D [Corynebacterium pseudotuberculosis C231] gi|308276746|gb|ADO26645.1| Ribosomal large subunit pseudouridine synthase D [Corynebacterium pseudotuberculosis I19] gi|341825186|gb|AEK92707.1| Ribosomal large subunit pseudouridine synthase D [Corynebacterium pseudotuberculosis PAT10] Length=307 Score = 419 bits (1078), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 207/304 (69%), Positives = 244/304 (81%), Gaps = 5/304 (1%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLAGMRVD L++LLG+SRT AA LA G V ++ +P GKSDR+ G L V Sbjct 5 RSLPVPEGLAGMRVDAALSKLLGISRTVAADLATAGDVLVDALPVGKSDRIAEGQWLDVT 64 Query 64 LPEAPAPLQNTPID--IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 LPE TP + +EGM ILYSDDD++AV+KP VAAH ++GW GPTV+GGLAAAG+ Sbjct 65 LPETK---DLTPREELVEGMDILYSDDDLIAVNKPVGVAAHPTLGWEGPTVIGGLAAAGF 121 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 RI+TSG ER+GIV RLDVGTSGVMV+A SER Y+VLKRAFK RTV K YHALVQGH DP Sbjct 122 RISTSGPPERKGIVQRLDVGTSGVMVIAASERGYSVLKRAFKERTVSKTYHALVQGHTDP 181 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 +GTIDAPIGRH W+FA+T +G+H++THY+TLEAF ASLL +HLETGRTHQIRVH Sbjct 182 FTGTIDAPIGRHPSAGWRFAVTSDGKHAVTHYETLEAFAEASLLKIHLETGRTHQIRVHM 241 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +ALHHPCCGD +YG+DPKL++RLGL RQWLHA SL F HPADGR +EI SPY DLQHAL Sbjct 242 SALHHPCCGDPMYGSDPKLSERLGLTRQWLHAVSLGFNHPADGRWMEITSPYSDDLQHAL 301 Query 302 KILR 305 ILR Sbjct 302 DILR 305 >gi|300858799|ref|YP_003783782.1| hypothetical protein cpfrc_01382 [Corynebacterium pseudotuberculosis FRC41] gi|300686253|gb|ADK29175.1| hypothetical protein cpfrc_01382 [Corynebacterium pseudotuberculosis FRC41] gi|302331059|gb|ADL21253.1| Ribosomal large subunit pseudouridine synthase D [Corynebacterium pseudotuberculosis 1002] Length=307 Score = 419 bits (1077), Expect = 3e-115, Method: Compositional matrix adjust. Identities = 207/304 (69%), Positives = 244/304 (81%), Gaps = 5/304 (1%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLAGMRVD L++LLG+SRT AA LA G V ++ +P GKSDR+ G L V Sbjct 5 RSLPVPEGLAGMRVDAALSKLLGISRTVAADLATAGDVLVDALPVGKSDRIAEGQWLDVT 64 Query 64 LPEAPAPLQNTPID--IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 LPE TP + +EGM ILYSDDD++AV+KP VAAH ++GW GPTV+GGLAAAG+ Sbjct 65 LPETK---DLTPREELVEGMDILYSDDDLIAVNKPVGVAAHPTLGWEGPTVIGGLAAAGF 121 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 RI+TSG ER+GIV RLDVGTSGVMV+A SER Y+VLKRAFK RTV K YHALVQGH DP Sbjct 122 RISTSGPPERKGIVQRLDVGTSGVMVIAASERGYSVLKRAFKERTVSKTYHALVQGHMDP 181 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 +GTIDAPIGRH W+FA+T +G+H++THY+TLEAF ASLL +HLETGRTHQIRVH Sbjct 182 FTGTIDAPIGRHPSAGWRFAVTSDGKHAVTHYETLEAFAEASLLKIHLETGRTHQIRVHM 241 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +ALHHPCCGD +YG+DPKL++RLGL RQWLHA SL F HPADGR +EI SPY DLQHAL Sbjct 242 SALHHPCCGDPMYGSDPKLSERLGLTRQWLHAVSLGFNHPADGRWMEITSPYSDDLQHAL 301 Query 302 KILR 305 ILR Sbjct 302 DILR 305 >gi|300784875|ref|YP_003765166.1| ribosomal large subunit pseudouridine synthase D [Amycolatopsis mediterranei U32] gi|299794389|gb|ADJ44764.1| ribosomal large subunit pseudouridine synthase D [Amycolatopsis mediterranei U32] gi|340526304|gb|AEK41509.1| ribosomal large subunit pseudouridine synthase D [Amycolatopsis mediterranei S699] Length=309 Score = 418 bits (1074), Expect = 6e-115, Method: Compositional matrix adjust. Identities = 210/307 (69%), Positives = 239/307 (78%), Gaps = 0/307 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M+ R +PVPDGL GMRVD GLA+LLGLSRT A LAE G V L+G PAGKSDRL G LL Sbjct 1 MSSRMLPVPDGLDGMRVDAGLAKLLGLSRTVVAELAESGDVLLDGRPAGKSDRLSGGGLL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 ++ LPE P++ ++GM IL+ DDDIV + KP VA H S GWTGPTV+GGLAAAG Sbjct 61 EITLPEPANPVEVVAQPVDGMQILHDDDDIVVISKPVGVAVHPSPGWTGPTVVGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 RI TSG ERQG+VHRLD GT+GVMVVA SE AYTVLKRAFK RTVDK YHA+VQGHPD Sbjct 121 LRIATSGAAERQGVVHRLDAGTTGVMVVAKSEHAYTVLKRAFKERTVDKGYHAIVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 P GTIDAPI RH H++KFA+ + GR S+THY+ +EAF AASL + LETGRTHQIRVH Sbjct 181 PMRGTIDAPIDRHPRHDYKFAVVQGGRPSVTHYEVVEAFRAASLTHIKLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+AL HPC GDL YGADP LA+ LGL RQWLHA++LAFAHPADGR VE S YP DL A Sbjct 241 FSALRHPCVGDLTYGADPVLARHLGLSRQWLHAKTLAFAHPADGRWVEFESEYPDDLAKA 300 Query 301 LKILRGE 307 L+ILR E Sbjct 301 LEILRDE 307 >gi|257056703|ref|YP_003134535.1| ribosomal large subunit pseudouridine synthase D [Saccharomonospora viridis DSM 43017] gi|256586575|gb|ACU97708.1| ribosomal large subunit pseudouridine synthase D [Saccharomonospora viridis DSM 43017] Length=308 Score = 417 bits (1071), Expect = 1e-114, Method: Compositional matrix adjust. Identities = 209/307 (69%), Positives = 240/307 (79%), Gaps = 0/307 (0%) Query 1 MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL 60 M+ R +PVPDGL GMRVD GLA+LLGLSRT A LA G V ++G A KSDRL +G LL Sbjct 1 MSSRMLPVPDGLDGMRVDVGLAKLLGLSRTVVAELAASGDVLIDGKVASKSDRLTAGDLL 60 Query 61 QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG 120 +V LPE P + + +EG+ IL+ DDDIV VDKP VA H S GWTGPTV+GGLAAAG Sbjct 61 EVTLPEPDTPAEVSAEPVEGLRILHEDDDIVVVDKPVGVAVHPSPGWTGPTVVGGLAAAG 120 Query 121 YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD 180 RI+TSG ERQG+VHRLD GT+GVMVVA SE AY+VLKRAFK RTV K YHALVQGHPD Sbjct 121 LRISTSGAAERQGVVHRLDAGTTGVMVVAKSEHAYSVLKRAFKERTVSKGYHALVQGHPD 180 Query 181 PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH 240 P+ GTIDAPI RH +++KFA+ G+ S+THY+ +EAF AASL+DV LETGRTHQIRVH Sbjct 181 PTRGTIDAPIDRHPRYDYKFAVVTGGKPSITHYEVIEAFRAASLVDVQLETGRTHQIRVH 240 Query 241 FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA 300 F+A+ HPC GDL YGADP LA+RLGL RQWLHAR+L FAHPADGR VE S YPADL A Sbjct 241 FSAMRHPCVGDLTYGADPVLARRLGLTRQWLHARTLGFAHPADGRWVEFTSEYPADLAAA 300 Query 301 LKILRGE 307 L ILR E Sbjct 301 LDILRAE 307 >gi|38234158|ref|NP_939925.1| putative pseudouridine synthase [Corynebacterium diphtheriae NCTC 13129] gi|38200420|emb|CAE50108.1| Putative pseudouridine synthase [Corynebacterium diphtheriae] Length=308 Score = 417 bits (1071), Expect = 1e-114, Method: Compositional matrix adjust. Identities = 211/306 (69%), Positives = 244/306 (80%), Gaps = 5/306 (1%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLAGMRVD L++LLG+SRTAAA LA G V ++G GKSDRL G L V Sbjct 6 RSLPVPEGLAGMRVDAALSKLLGISRTAAADLAIAGDVVVDGHCVGKSDRLSEGQWLDVT 65 Query 64 LPEAPAPLQNTPID--IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 LPE TP + IEGM ILYSDDD++AV+KP VAAH ++GW GPTV+GGLAAAG+ Sbjct 66 LPEV---RDLTPREELIEGMDILYSDDDVIAVNKPVGVAAHPTLGWEGPTVIGGLAAAGF 122 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 RI+TSG ER+GIV RLDVGTSGVMVVA SER Y+VLKRAFK RTV K YH+LVQGH DP Sbjct 123 RISTSGPPERKGIVQRLDVGTSGVMVVAASERGYSVLKRAFKERTVTKTYHSLVQGHMDP 182 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 SGTIDAPIGRH W+FA+T +G+H++THY+T+EAF ASLL +HLETGRTHQIRVH Sbjct 183 LSGTIDAPIGRHPSAGWRFAVTTDGKHAVTHYETIEAFAEASLLRIHLETGRTHQIRVHM 242 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +ALHHPCCGD +YG+DP L+ RLGLDRQWLHA SL F HPADGR VEI SPY DLQHAL Sbjct 243 SALHHPCCGDPMYGSDPALSARLGLDRQWLHAVSLGFHHPADGRWVEIESPYSKDLQHAL 302 Query 302 KILRGE 307 +LR E Sbjct 303 DVLRSE 308 >gi|337291104|ref|YP_004630125.1| hypothetical protein CULC22_01496 [Corynebacterium ulcerans BR-AD22] gi|334697216|gb|AEG82013.1| hypothetical protein CULC809_01481 [Corynebacterium ulcerans 809] gi|334699410|gb|AEG84206.1| hypothetical protein CULC22_01496 [Corynebacterium ulcerans BR-AD22] Length=307 Score = 416 bits (1070), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 205/304 (68%), Positives = 243/304 (80%), Gaps = 5/304 (1%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLAGMR+D L++LLG+SRT AA LA G V ++ P GKSDR+ G L V Sbjct 5 RSLPVPEGLAGMRIDAALSKLLGISRTVAADLATAGDVLVDATPVGKSDRIAEGQWLDVT 64 Query 64 LPEAPAPLQNTPID--IEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 LPE TP + +EGM ILYSDDD++AV+KP VAAH ++GW GPTV+GGLAAAG+ Sbjct 65 LPETK---DLTPREELVEGMDILYSDDDLIAVNKPVGVAAHPTLGWEGPTVIGGLAAAGF 121 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 RI+TSG ER+GIV RLDVGTSGVMV+A SER Y+VLKRAFK RTV K YHALVQGH DP Sbjct 122 RISTSGPPERKGIVQRLDVGTSGVMVIAASERGYSVLKRAFKERTVSKTYHALVQGHMDP 181 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 +GTIDAPIGRH W+FA+T +G+H++THY+TLEAF ASLL +HLETGRTHQIRVH Sbjct 182 FTGTIDAPIGRHPSAGWRFAVTSDGKHAVTHYETLEAFAEASLLKIHLETGRTHQIRVHM 241 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +ALHHPCCGD +YG+DPKL++RLGL RQWLHA SL F HPADGR +EI SPY DLQHAL Sbjct 242 SALHHPCCGDPMYGSDPKLSERLGLVRQWLHAVSLGFHHPADGRWMEITSPYSDDLQHAL 301 Query 302 KILR 305 +LR Sbjct 302 DVLR 305 >gi|319949599|ref|ZP_08023642.1| pseudouridine synthase, RluA family protein [Dietzia cinnamea P4] gi|319436736|gb|EFV91813.1| pseudouridine synthase, RluA family protein [Dietzia cinnamea P4] Length=308 Score = 415 bits (1066), Expect = 5e-114, Method: Compositional matrix adjust. Identities = 206/302 (69%), Positives = 241/302 (80%), Gaps = 0/302 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R+ PVPDGL GMRVD G++RLLG+SRTA A LA EG V L+G GKSD+L + ++V Sbjct 5 RTFPVPDGLDGMRVDAGVSRLLGISRTAVADLAGEGKVLLDGRTVGKSDKLTGMSWIEVE 64 Query 64 LPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYRI 123 +PE A + GM ++YSD DIV VDKP VAAHASVGWTGPTV+GGLAAAGYRI Sbjct 65 MPEPRAEPAVVAEPVAGMAVVYSDADIVVVDKPVGVAAHASVGWTGPTVIGGLAAAGYRI 124 Query 124 TTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPSS 183 +TSG ER+GIVHRLDVGTSG+MVVA SERAYT+LKRAF+ RTVDK YHALVQGHPDP S Sbjct 125 STSGPPERKGIVHRLDVGTSGLMVVAASERAYTLLKRAFRDRTVDKTYHALVQGHPDPLS 184 Query 184 GTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFAA 243 GTIDAPIGRH ++W+FA+ +G+ S+THYDTLEA AA+L++V LETGRTHQIRVHF+A Sbjct 185 GTIDAPIGRHTSNDWRFAVISDGKPSITHYDTLEAHQAATLVEVKLETGRTHQIRVHFSA 244 Query 244 LHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALKI 303 LHHPC GDL YGADP LA+RLGL+RQWLHA L F HP G RV+ S YP DLQHA+ + Sbjct 245 LHHPCAGDLTYGADPVLARRLGLERQWLHAVGLGFEHPGTGARVDFESRYPDDLQHAIDV 304 Query 304 LR 305 LR Sbjct 305 LR 306 >gi|334564624|ref|ZP_08517615.1| pseudouridylate synthase [Corynebacterium bovis DSM 20582] Length=310 Score = 415 bits (1066), Expect = 6e-114, Method: Compositional matrix adjust. Identities = 207/303 (69%), Positives = 244/303 (81%), Gaps = 2/303 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 R+MPVP GLAGMRVD G+ARLLGLSRT A LA+ G + +GV AG+SDRL GA L V Sbjct 6 RAMPVPAGLAGMRVDAGVARLLGLSRTVVAGLADAGDITQDGVTAGRSDRLTDGAWLDVL 65 Query 64 LPEAPAPLQNTPI-DIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGYR 122 LPE P L P ++EG+ ILY+DDD++AVDKP VAAH ++GW GPTV GLAAAG+R Sbjct 66 LPEPPRDLAAEPAREVEGLDILYADDDVIAVDKPVGVAAHPTIGWEGPTVTSGLAAAGFR 125 Query 123 ITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDPS 182 I+TSG ER+GIV RLDVGTSGVMVVA SERAYTVLKRAF+ RTV+K YHALVQGHPDP+ Sbjct 126 ISTSGPPERKGIVQRLDVGTSGVMVVAASERAYTVLKRAFRDRTVEKTYHALVQGHPDPT 185 Query 183 SGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHFA 242 SGT+DAPIGRH G W+FA+ +G+ ++THY T+EAF ASLL VHLETGRTHQIRVHF+ Sbjct 186 SGTVDAPIGRHPGAGWRFAVRDDGKRAVTHYGTIEAFREASLLRVHLETGRTHQIRVHFS 245 Query 243 ALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALK 302 ALHHPCCGD +YG+DP L++RLGL+RQWLHA L F HP DGR +++ SPYPADL AL Sbjct 246 ALHHPCCGDPMYGSDPALSRRLGLNRQWLHAVHLGFTHP-DGRWMDVESPYPADLATALD 304 Query 303 ILR 305 LR Sbjct 305 RLR 307 >gi|317508658|ref|ZP_07966314.1| RluA family pseudouridine synthase [Segniliparus rugosus ATCC BAA-974] gi|316253061|gb|EFV12475.1| RluA family pseudouridine synthase [Segniliparus rugosus ATCC BAA-974] Length=315 Score = 415 bits (1066), Expect = 6e-114, Method: Compositional matrix adjust. Identities = 205/304 (68%), Positives = 247/304 (82%), Gaps = 2/304 (0%) Query 4 RSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALLQVR 63 RS+PVP+GLAG+R+D GLARLLG+SRT AA LA+ G ++G AG+SDRLV+GA L+V Sbjct 9 RSLPVPEGLAGLRLDAGLARLLGVSRTKAAELADAGHALIDGKEAGRSDRLVAGAWLEVS 68 Query 64 LPEAP-APLQ-NTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAGY 121 +P AP AP++ + P I G+ +LYSD+ +V V+KP +A H SVGW+GPTV+GGL A G+ Sbjct 69 VPSAPSAPVEEDAPEIIPGLNVLYSDEHVVVVEKPPEIAVHPSVGWSGPTVVGGLKALGF 128 Query 122 RITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPDP 181 I T+GV ERQG+V RLDVGTSGVMV+A SE AYTVLKRAFK+R V+K Y ALVQGHPDP Sbjct 129 HIATTGVAERQGVVQRLDVGTSGVMVLAASEHAYTVLKRAFKHREVEKWYEALVQGHPDP 188 Query 182 SSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVHF 241 SSGTIDAPIG+ G W+FA+T GRHS+THYDT+EAF AASL+ V LETGRTHQIRVHF Sbjct 189 SSGTIDAPIGKRPGPGWRFAVTTEGRHSVTHYDTIEAFGAASLVSVKLETGRTHQIRVHF 248 Query 242 AALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHAL 301 +AL HPCCGD++YGADPKLA RLGL RQWLHAR L+FAHPADG+ + S P DLQHAL Sbjct 249 SALRHPCCGDMLYGADPKLAARLGLRRQWLHARRLSFAHPADGKIMRFESELPQDLQHAL 308 Query 302 KILR 305 +LR Sbjct 309 GVLR 312 Lambda K H 0.320 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 524399257434 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40