BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1556
Length=202
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608694|ref|NP_216072.1| regulatory protein [Mycobacterium t... 405 2e-111
gi|289745311|ref|ZP_06504689.1| transcriptional regulator [Mycob... 402 2e-110
gi|308377765|ref|ZP_07480326.2| putative transcriptional regulat... 364 5e-99
gi|339294531|gb|AEJ46642.1| regulatory protein [Mycobacterium tu... 350 7e-95
gi|118617528|ref|YP_905860.1| regulatory protein [Mycobacterium ... 324 4e-87
gi|41409150|ref|NP_961986.1| hypothetical protein MAP3052c [Myco... 322 2e-86
gi|240171019|ref|ZP_04749678.1| putative regulatory protein [Myc... 320 1e-85
gi|183981709|ref|YP_001850000.1| regulatory protein [Mycobacteri... 320 1e-85
gi|118462921|ref|YP_883029.1| TetR family transcriptional regula... 313 8e-84
gi|342858161|ref|ZP_08714816.1| hypothetical protein MCOL_04786 ... 310 1e-82
gi|254820446|ref|ZP_05225447.1| hypothetical protein MintA_10986... 308 4e-82
gi|254550576|ref|ZP_05141023.1| regulatory protein [Mycobacteriu... 307 6e-82
gi|333989518|ref|YP_004522132.1| regulatory protein [Mycobacteri... 294 5e-78
gi|169628086|ref|YP_001701735.1| putative HTH-type transcription... 247 6e-64
gi|145223608|ref|YP_001134286.1| TetR family transcriptional reg... 231 6e-59
gi|296171260|ref|ZP_06852664.1| TetR family transcriptional regu... 228 5e-58
gi|294629843|ref|ZP_06708403.1| TetR-family transcriptional regu... 116 2e-24
gi|21221604|ref|NP_627383.1| TetR family transcriptional regulat... 115 5e-24
gi|29830162|ref|NP_824796.1| TetR family transcriptional regulat... 113 2e-23
gi|326331593|ref|ZP_08197883.1| transcriptional regulator, TetR ... 112 2e-23
gi|118462932|ref|YP_882972.1| HTH-type transcriptional regulator... 107 9e-22
gi|119717663|ref|YP_924628.1| TetR family transcriptional regula... 106 2e-21
gi|256396574|ref|YP_003118138.1| TetR family transcriptional reg... 105 3e-21
gi|158317650|ref|YP_001510158.1| TetR family transcriptional reg... 105 5e-21
gi|302552026|ref|ZP_07304368.1| TetR family transcriptional regu... 103 1e-20
gi|290959724|ref|YP_003490906.1| TetR family transcriptional reg... 103 1e-20
gi|329941226|ref|ZP_08290505.1| TetR family transcriptional regu... 103 1e-20
gi|291439115|ref|ZP_06578505.1| tetR-family transcriptional regu... 102 3e-20
gi|297560577|ref|YP_003679551.1| TetR family transcriptional reg... 102 3e-20
gi|152966002|ref|YP_001361786.1| TetR family transcriptional reg... 100 1e-19
gi|297200299|ref|ZP_06917696.1| TetR-family transcriptional regu... 99.4 3e-19
gi|299138004|ref|ZP_07031184.1| transcriptional regulator, TetR ... 99.0 3e-19
gi|333026382|ref|ZP_08454446.1| putative TetR family transcripti... 98.6 5e-19
gi|295838290|ref|ZP_06825223.1| TetR-family transcriptional regu... 97.8 8e-19
gi|288916466|ref|ZP_06410843.1| transcriptional regulator, TetR ... 97.8 9e-19
gi|302519804|ref|ZP_07272146.1| TetR-family transcriptional regu... 97.4 1e-18
gi|336179625|ref|YP_004585000.1| regulatory protein TetR [Franki... 94.7 7e-18
gi|297202854|ref|ZP_06920251.1| transcriptional regulator [Strep... 94.0 1e-17
gi|86739419|ref|YP_479819.1| TetR family transcriptional regulat... 94.0 1e-17
gi|328883048|emb|CCA56287.1| Transcriptional regulator, TetR fam... 92.8 3e-17
gi|284034193|ref|YP_003384124.1| TetR family transcriptional reg... 92.0 4e-17
gi|297193892|ref|ZP_06911290.1| TetR-family transcriptional regu... 92.0 5e-17
gi|291453534|ref|ZP_06592924.1| TetR-family transcriptional regu... 91.7 6e-17
gi|256392361|ref|YP_003113925.1| TetR family transcriptional reg... 91.3 7e-17
gi|302560179|ref|ZP_07312521.1| TetR-family transcriptional regu... 91.3 7e-17
gi|254388839|ref|ZP_05004071.1| TetR-family transcriptional regu... 90.9 9e-17
gi|295835609|ref|ZP_06822542.1| TetR family transcriptional regu... 90.9 1e-16
gi|291436843|ref|ZP_06576233.1| transcriptional regulator [Strep... 89.7 2e-16
gi|182438110|ref|YP_001825829.1| TetR family transcriptional reg... 89.7 2e-16
gi|297157805|gb|ADI07517.1| TetR family transcriptional regulato... 89.4 3e-16
>gi|15608694|ref|NP_216072.1| regulatory protein [Mycobacterium tuberculosis H37Rv]
gi|15841023|ref|NP_336060.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31792740|ref|NP_855233.1| regulatory protein [Mycobacterium bovis AF2122/97]
75 more sequence titles
Length=202
Score = 405 bits (1042), Expect = 2e-111, Method: Compositional matrix adjust.
Identities = 202/202 (100%), Positives = 202/202 (100%), Gaps = 0/202 (0%)
Query 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR
Sbjct 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
Query 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN
Sbjct 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
Query 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP
Sbjct 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
Query 181 TQDTVQALVDDVILPSLTRSTG 202
TQDTVQALVDDVILPSLTRSTG
Sbjct 181 TQDTVQALVDDVILPSLTRSTG 202
>gi|289745311|ref|ZP_06504689.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
gi|289685839|gb|EFD53327.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
Length=202
Score = 402 bits (1033), Expect = 2e-110, Method: Compositional matrix adjust.
Identities = 201/202 (99%), Positives = 201/202 (99%), Gaps = 0/202 (0%)
Query 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASA ASKATVYRR
Sbjct 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASAPASKATVYRR 60
Query 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN
Sbjct 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
Query 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP
Sbjct 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
Query 181 TQDTVQALVDDVILPSLTRSTG 202
TQDTVQALVDDVILPSLTRSTG
Sbjct 181 TQDTVQALVDDVILPSLTRSTG 202
>gi|308377765|ref|ZP_07480326.2| putative transcriptional regulator, TetR family [Mycobacterium
tuberculosis SUMu009]
gi|308354722|gb|EFP43573.1| putative transcriptional regulator, TetR family [Mycobacterium
tuberculosis SUMu009]
Length=180
Score = 364 bits (934), Expect = 5e-99, Method: Compositional matrix adjust.
Identities = 180/180 (100%), Positives = 180/180 (100%), Gaps = 0/180 (0%)
Query 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR
Sbjct 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
Query 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN
Sbjct 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
Query 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP
Sbjct 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
>gi|339294531|gb|AEJ46642.1| regulatory protein [Mycobacterium tuberculosis CCDC5079]
gi|339298167|gb|AEJ50277.1| regulatory protein [Mycobacterium tuberculosis CCDC5180]
Length=175
Score = 350 bits (898), Expect = 7e-95, Method: Compositional matrix adjust.
Identities = 174/175 (99%), Positives = 175/175 (100%), Gaps = 0/175 (0%)
Query 28 VTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN 87
+TLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN
Sbjct 1 MTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN 60
Query 88 LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 147
LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV
Sbjct 61 LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 120
Query 148 DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG 202
DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG
Sbjct 121 DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG 175
>gi|118617528|ref|YP_905860.1| regulatory protein [Mycobacterium ulcerans Agy99]
gi|118569638|gb|ABL04389.1| regulatory protein [Mycobacterium ulcerans Agy99]
Length=201
Score = 324 bits (831), Expect = 4e-87, Method: Compositional matrix adjust.
Identities = 159/201 (80%), Positives = 178/201 (89%), Gaps = 0/201 (0%)
Query 2 VGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRW 61
+GA+TQ ADR SPWSPRE ELLAVTL+LLQEHGYDRLT+DAVA +ARASKATVYRRW
Sbjct 1 MGAMTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVANTARASKATVYRRW 60
Query 62 PSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNP 121
PSKAELVLAAFIEG+RQVAV PNTG+LRDDL+++GE IC + Q ASTIRAVLVEVSR+P
Sbjct 61 PSKAELVLAAFIEGVRQVAVAPNTGSLRDDLVKIGEGICGQAHQQASTIRAVLVEVSRHP 120
Query 122 ALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPT 181
AL+D LQ QFVD RKALIQ +LQQAVDRGEI+ AAI+DELWDLLPGYLIFRSIIPNRPPT
Sbjct 121 ALSDALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPT 180
Query 182 QDTVQALVDDVILPSLTRSTG 202
TVQ LVDD I+P LT++TG
Sbjct 181 PHTVQLLVDDFIMPGLTQATG 201
>gi|41409150|ref|NP_961986.1| hypothetical protein MAP3052c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|254776287|ref|ZP_05217803.1| hypothetical protein MaviaA2_16677 [Mycobacterium avium subsp.
avium ATCC 25291]
gi|41397970|gb|AAS05600.1| hypothetical protein MAP_3052c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336459171|gb|EGO38118.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=200
Score = 322 bits (825), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 154/198 (78%), Positives = 174/198 (88%), Gaps = 0/198 (0%)
Query 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
MVGA+TQ ADR SPWSPRE E+LAVTLRLLQEHGYD+LTVDAVA +A ASKATVYRR
Sbjct 1 MVGAMTQTADRCEQASPWSPREAEILAVTLRLLQEHGYDQLTVDAVAGAAHASKATVYRR 60
Query 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
WPSKAELVLAAFIEG+RQVAVPPNTG LR DLL LGE +C +VG HASTIRAV+ EVSR+
Sbjct 61 WPSKAELVLAAFIEGVRQVAVPPNTGTLRGDLLALGETVCEQVGHHASTIRAVMFEVSRH 120
Query 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
PALND LQHQF+D R+ALI+++L QAVDRGEIS+ AISDELWDLLPGYLIFRSI+P RPP
Sbjct 121 PALNDALQHQFLDQRRALIEHVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPP 180
Query 181 TQDTVQALVDDVILPSLT 198
++ TVQALVD ++P LT
Sbjct 181 SRRTVQALVDGFLIPGLT 198
>gi|240171019|ref|ZP_04749678.1| putative regulatory protein [Mycobacterium kansasii ATCC 12478]
Length=201
Score = 320 bits (819), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 159/200 (80%), Positives = 181/200 (91%), Gaps = 0/200 (0%)
Query 2 VGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRW 61
+GAVTQIADR + S WSPRE ELLAVTL+LLQ+HGYDRLTVDAVAA+ARASKATVYRRW
Sbjct 1 MGAVTQIADRSSQSSSWSPREAELLAVTLQLLQQHGYDRLTVDAVAATARASKATVYRRW 60
Query 62 PSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNP 121
PSKAELVLAAF+EGIRQV VPP+TG LR DLL+LGEL+C + QH STIRAVLVEV+RNP
Sbjct 61 PSKAELVLAAFVEGIRQVVVPPDTGTLRGDLLQLGELVCEQARQHTSTIRAVLVEVARNP 120
Query 122 ALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPT 181
ALNDV+QHQFVD RKAL+ +I+QQAVDRGEI AAI DELWD+LPGYL+FR I+P+RPPT
Sbjct 121 ALNDVMQHQFVDQRKALMHHIVQQAVDRGEIDGAAIDDELWDVLPGYLMFRFIVPSRPPT 180
Query 182 QDTVQALVDDVILPSLTRST 201
+ TVQALVD++ILPSLTRST
Sbjct 181 RRTVQALVDNIILPSLTRST 200
>gi|183981709|ref|YP_001850000.1| regulatory protein [Mycobacterium marinum M]
gi|183175035|gb|ACC40145.1| regulatory protein [Mycobacterium marinum M]
Length=198
Score = 320 bits (819), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 157/198 (80%), Positives = 175/198 (89%), Gaps = 0/198 (0%)
Query 5 VTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSK 64
+TQ ADR SPWSPRE ELLAVTL+LLQEHGYDRLT+DAVA +ARASKATVYRRWPSK
Sbjct 1 MTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVANTARASKATVYRRWPSK 60
Query 65 AELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALN 124
AELVLAAFIEG+RQVAV PNTG+LRDDL+++GE IC + Q ASTIRAVLVEVSR+PAL+
Sbjct 61 AELVLAAFIEGVRQVAVAPNTGSLRDDLVKIGEGICGQAHQQASTIRAVLVEVSRHPALS 120
Query 125 DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDT 184
D LQ QFVD RKALIQ +LQQAVDRGEI+ AAI+DELWDLLPGYLIFRSIIPNRPPT T
Sbjct 121 DALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPHT 180
Query 185 VQALVDDVILPSLTRSTG 202
VQ LVDD I+P LT++TG
Sbjct 181 VQLLVDDFIMPGLTQATG 198
>gi|118462921|ref|YP_883029.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118164208|gb|ABK65105.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=196
Score = 313 bits (802), Expect = 8e-84, Method: Compositional matrix adjust.
Identities = 150/194 (78%), Positives = 170/194 (88%), Gaps = 0/194 (0%)
Query 5 VTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSK 64
+TQ ADR SPWSPRE E+LAVTLRLLQEHGYD+LTVDAVA +A ASKATVYRRWPSK
Sbjct 1 MTQTADRCEQASPWSPREAEILAVTLRLLQEHGYDQLTVDAVAGAAHASKATVYRRWPSK 60
Query 65 AELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALN 124
AELVLAAFIEG+RQVAVPPNTG LR DLL LGE +C +VG HASTIRAV+ EVSR+PALN
Sbjct 61 AELVLAAFIEGVRQVAVPPNTGTLRGDLLALGETVCEQVGHHASTIRAVMFEVSRHPALN 120
Query 125 DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDT 184
D LQHQF+D R+ALI+++L QAVDRGEIS+ AISDELWDLLPGYLIFRSI+P RPP++ T
Sbjct 121 DALQHQFLDQRRALIEHVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSRRT 180
Query 185 VQALVDDVILPSLT 198
VQALVD ++P LT
Sbjct 181 VQALVDGFLIPGLT 194
>gi|342858161|ref|ZP_08714816.1| hypothetical protein MCOL_04786 [Mycobacterium colombiense CECT
3035]
gi|342133865|gb|EGT87045.1| hypothetical protein MCOL_04786 [Mycobacterium colombiense CECT
3035]
Length=198
Score = 310 bits (793), Expect = 1e-82, Method: Compositional matrix adjust.
Identities = 149/198 (76%), Positives = 168/198 (85%), Gaps = 0/198 (0%)
Query 5 VTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSK 64
+TQ ADR SPWSPRE E+LAVTL LLQEHGYD+LTVDAVA +ARASKATVYRRWPSK
Sbjct 1 MTQTADRCEHASPWSPREAEILAVTLALLQEHGYDQLTVDAVANAARASKATVYRRWPSK 60
Query 65 AELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALN 124
AELVLAAFIEG+RQVAVPPNTG LR DLL LGE I +E GQHA TIRAV+VEVSR+PALN
Sbjct 61 AELVLAAFIEGVRQVAVPPNTGTLRGDLLSLGETISQECGQHAGTIRAVMVEVSRHPALN 120
Query 125 DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDT 184
+ +QHQF+D RKA IQ++L QA DRGEIS I+DELWDLLPGYLIFRSI+P RPPT+ T
Sbjct 121 EAMQHQFLDQRKATIQHVLHQAADRGEISEDVITDELWDLLPGYLIFRSILPGRPPTRRT 180
Query 185 VQALVDDVILPSLTRSTG 202
V+A VD ++P LTRS G
Sbjct 181 VEAFVDGFLIPGLTRSAG 198
>gi|254820446|ref|ZP_05225447.1| hypothetical protein MintA_10986 [Mycobacterium intracellulare
ATCC 13950]
Length=199
Score = 308 bits (788), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 149/198 (76%), Positives = 167/198 (85%), Gaps = 0/198 (0%)
Query 5 VTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSK 64
+TQ A+ SPWSPRE E+LAVTLRLLQEHGYD+L VDAVA +ARASKATVYRRWPSK
Sbjct 1 MTQTAEECAQASPWSPREAEILAVTLRLLQEHGYDQLAVDAVANAARASKATVYRRWPSK 60
Query 65 AELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALN 124
AELVLAAFIEG+RQVAVPPNTG LR DLL LGE I E GQHASTIRAV+VEVSR+PALN
Sbjct 61 AELVLAAFIEGVRQVAVPPNTGTLRGDLLSLGETIAVECGQHASTIRAVMVEVSRHPALN 120
Query 125 DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDT 184
+ LQHQF+D RKA+IQ++L QAVDRGEI+ I+DELWDLLPGYLIFRSIIP RPPT+ T
Sbjct 121 EALQHQFLDQRKAMIQHVLHQAVDRGEITEDVITDELWDLLPGYLIFRSIIPGRPPTRRT 180
Query 185 VQALVDDVILPSLTRSTG 202
VQA VD ++P LT G
Sbjct 181 VQAFVDGFLIPGLTAGPG 198
>gi|254550576|ref|ZP_05141023.1| regulatory protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
Length=164
Score = 307 bits (786), Expect = 6e-82, Method: Compositional matrix adjust.
Identities = 152/158 (97%), Positives = 154/158 (98%), Gaps = 0/158 (0%)
Query 28 VTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN 87
+TLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN
Sbjct 1 MTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGN 60
Query 88 LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 147
LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV
Sbjct 61 LRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAV 120
Query 148 DRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTV 185
DRGEISSAAISDELWDLLPGYLIFRSIIPNR T D+
Sbjct 121 DRGEISSAAISDELWDLLPGYLIFRSIIPNRRSTPDSC 158
>gi|333989518|ref|YP_004522132.1| regulatory protein [Mycobacterium sp. JDM601]
gi|333485486|gb|AEF34878.1| regulatory protein [Mycobacterium sp. JDM601]
Length=201
Score = 294 bits (752), Expect = 5e-78, Method: Compositional matrix adjust.
Identities = 148/201 (74%), Positives = 167/201 (84%), Gaps = 1/201 (0%)
Query 1 MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRR 60
MV AV+Q D S WSPRE ELL VTL+LLQE+GYDRLTVDAVAA+ARASKATVYRR
Sbjct 1 MVDAVSQNLD-VAGTSTWSPREVELLEVTLQLLQENGYDRLTVDAVAATARASKATVYRR 59
Query 61 WPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRN 120
WPSKAELVLAAF EGIRQVAVPP+TG+LR DLLRLGEL+C + QHA TIRAVLVEVSRN
Sbjct 60 WPSKAELVLAAFTEGIRQVAVPPDTGSLRGDLLRLGELVCEQTTQHAGTIRAVLVEVSRN 119
Query 121 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPP 180
PALND +Q QF+D RKAL+ +IL QAVDRGEI +AAI+D+LWD+LPGYLIFRS++ R
Sbjct 120 PALNDAMQRQFIDQRKALMLHILGQAVDRGEIDAAAINDDLWDVLPGYLIFRSLVSGRAA 179
Query 181 TQDTVQALVDDVILPSLTRST 201
T TV LVD V+LP LTR T
Sbjct 180 TARTVANLVDQVVLPGLTRGT 200
>gi|169628086|ref|YP_001701735.1| putative HTH-type transcriptional regulator TetR [Mycobacterium
abscessus ATCC 19977]
gi|169240053|emb|CAM61081.1| Putative HTH-type transcriptional regulator TetR [Mycobacterium
abscessus]
Length=204
Score = 247 bits (631), Expect = 6e-64, Method: Compositional matrix adjust.
Identities = 121/191 (64%), Positives = 149/191 (79%), Gaps = 0/191 (0%)
Query 9 ADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELV 68
A R S W+PRE ELL VTLRLLQEHGYDRL+VD VAA ++ASKAT+YRRWPSKAELV
Sbjct 12 AARGRQVSQWTPREVELLKVTLRLLQEHGYDRLSVDEVAAESKASKATIYRRWPSKAELV 71
Query 69 LAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQ 128
LAAFIEG+R V PNTG+LR+DLLR+G +V ++ +R +L+E+ RNPAL +
Sbjct 72 LAAFIEGMRAQLVRPNTGSLREDLLRIGTNALADVRRNTPVMRGLLIEIERNPALTKAFR 131
Query 129 HQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQAL 188
+FVD RKALI +L AV RGEI + A+++ELWDLLPGYL+FRS++P R PT DTV+ L
Sbjct 132 TKFVDERKALIDDVLFAAVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTADTVRTL 191
Query 189 VDDVILPSLTR 199
VDDVI+PSLTR
Sbjct 192 VDDVIMPSLTR 202
>gi|145223608|ref|YP_001134286.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|145216094|gb|ABP45498.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
Length=210
Score = 231 bits (588), Expect = 6e-59, Method: Compositional matrix adjust.
Identities = 112/191 (59%), Positives = 148/191 (78%), Gaps = 2/191 (1%)
Query 9 ADRPTDP--SPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAE 66
+D P+ P S + RE +LL +TL+ LQ+HGYDRLTV+AVA A+ASKAT+YRRWPSK++
Sbjct 9 SDPPSAPLKSRRTAREAQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSD 68
Query 67 LVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDV 126
LVLAAF+EG R AVPP TG+LRDDLLR+G +C++ +HAST+RAVL E+S NP L
Sbjct 69 LVLAAFVEGTRLAAVPPRTGSLRDDLLRVGASVCQQACEHASTMRAVLNEMSHNPDLRKA 128
Query 127 LQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQ 186
+Q +FV K +I +L +AV RGEI + AISDE++DLLPGYL+FR+++ RPPT +V+
Sbjct 129 MQDEFVHQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLKSVR 188
Query 187 ALVDDVILPSL 197
LVD V+LPSL
Sbjct 189 TLVDKVLLPSL 199
>gi|296171260|ref|ZP_06852664.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295894228|gb|EFG73985.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=158
Score = 228 bits (580), Expect = 5e-58, Method: Compositional matrix adjust.
Identities = 110/154 (72%), Positives = 127/154 (83%), Gaps = 0/154 (0%)
Query 6 TQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKA 65
TQ T SPWSPRE E+LAVTLRLL EHGYD+LTV+AVA +A ASKATVYRRWPSKA
Sbjct 5 TQTVQECTQASPWSPREAEILAVTLRLLHEHGYDQLTVEAVAGAAHASKATVYRRWPSKA 64
Query 66 ELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALND 125
ELVLAAFIEG+RQVA+PPNTG LR DLL +GE + +HASTIRAV+VEVSR+PALND
Sbjct 65 ELVLAAFIEGVRQVALPPNTGTLRGDLLSMGETCGQHGAEHASTIRAVMVEVSRHPALND 124
Query 126 VLQHQFVDHRKALIQYILQQAVDRGEISSAAISD 159
LQ QF+ RKALIQ++L+QAVDRGEIS ++D
Sbjct 125 ALQEQFLKQRKALIQHVLRQAVDRGEISEDVVTD 158
>gi|294629843|ref|ZP_06708403.1| TetR-family transcriptional regulator [Streptomyces sp. e14]
gi|292833176|gb|EFF91525.1| TetR-family transcriptional regulator [Streptomyces sp. e14]
Length=199
Score = 116 bits (291), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 68/182 (38%), Positives = 110/182 (61%), Gaps = 8/182 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL A L LL+E GYD LT+DAVAA R+SKAT+YR+W KAELV+ A
Sbjct 16 REAELYAAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGGKAELVVRAVRHDKPSSF 75
Query 81 VPPNTGNLRDDLLRLGELICRE----VGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
+TG+LR D L L+ RE + Q+++ +R + + + NP L + Q ++
Sbjct 76 DGTDTGSLRGD---LHALVAREDDCTMEQNSALMRGLAMAMHNNPDLRQAFREQLIEPET 132
Query 137 ALIQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
A ++++AVDRGE+ + + D + ++ G + R+++ ++PPTQD +++ +D V+LP
Sbjct 133 AAFNRLVRRAVDRGEVRADCPALDFVVHMMAGGFVVRALMEDQPPTQDFLRSYIDAVVLP 192
Query 196 SL 197
+L
Sbjct 193 AL 194
>gi|21221604|ref|NP_627383.1| TetR family transcriptional regulator [Streptomyces coelicolor
A3(2)]
gi|289771104|ref|ZP_06530482.1| TetR family transcriptional regulator [Streptomyces lividans
TK24]
gi|6138852|emb|CAB59663.1| putative tetR-family transcriptional regulator [Streptomyces
coelicolor A3(2)]
gi|289701303|gb|EFD68732.1| TetR family transcriptional regulator [Streptomyces lividans
TK24]
Length=199
Score = 115 bits (287), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 73/186 (40%), Positives = 110/186 (60%), Gaps = 8/186 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GYD LT+DAVAA R+SKAT+YR+W K ELV+ A
Sbjct 16 REAELYEAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGGKPELVVKAIRHNKPGEI 75
Query 81 VPPNTGNLRDDLLRLGELICRE----VGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
+TG+LR D L L+ RE + Q+++ +R V + + +NP L + Q ++
Sbjct 76 GDVDTGSLRGD---LHALMVREDDCTMEQNSALMRGVAMALHQNPDLRQAFREQLIEPEM 132
Query 137 ALIQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
A Q +LQ+AVDRGEI + + D L ++ G R+++ ++PPT++ + + +D VILP
Sbjct 133 AEFQRVLQRAVDRGEIRADCPALDFLVHMMVGGFATRTLLDDQPPTREFLASYIDAVILP 192
Query 196 SLTRST 201
+L ST
Sbjct 193 ALGVST 198
>gi|29830162|ref|NP_824796.1| TetR family transcriptional regulator [Streptomyces avermitilis
MA-4680]
gi|29607272|dbj|BAC71331.1| putative TetR-family transcriptional regulator [Streptomyces
avermitilis MA-4680]
Length=196
Score = 113 bits (283), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 73/180 (41%), Positives = 105/180 (59%), Gaps = 4/180 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL + L LL+E GYD LT+DAVA+ R+SKAT+YR+W KAELV+ A
Sbjct 16 REAELYSAVLDLLREVGYDALTMDAVASRTRSSKATLYRQWGGKAELVVKALRHQKHSHF 75
Query 81 VPPNTGNLRDDLLRL--GELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKAL 138
+TG+LR D L E C E+ Q+++ +R + V V NP L D + +D
Sbjct 76 GEVDTGSLRGDFHALVTRENNC-EMEQNSALMRGLAVAVHANPDLLDAFRDLIIDPETNE 134
Query 139 IQYILQQAVDRGEI-SSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+Q +LQ+AVDRGEI + + + +L G R++I PPTQ+ + + VD V+LP+L
Sbjct 135 MQRLLQRAVDRGEIRADNPATQYVLHMLIGAFAARTLIDELPPTQEFLTSYVDAVVLPAL 194
>gi|326331593|ref|ZP_08197883.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
gi|325950849|gb|EGD42899.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
Length=202
Score = 112 bits (281), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 65/190 (35%), Positives = 105/190 (56%), Gaps = 8/190 (4%)
Query 15 PSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIE 74
P RE E+ T+ +L E GYDRLT+DAVA A+ASKAT+YRRW KA+LV+ A +
Sbjct 17 PRVEGEREQEIFDATIDILAELGYDRLTMDAVAGRAKASKATLYRRWNGKAQLVIEA-LT 75
Query 75 GIRQVAVPPNTGNLRDDLLRLGELICREVG----QHASTIRAVLVEVSRNPALNDVLQHQ 130
++ P+TG+LR+DLL C G + + +V+ +SR+ + +
Sbjct 76 STKEPMTAPDTGDLREDLL---GAFCGMGGLTDQRQIAIFGSVVTAISRDAEFAEAFRRG 132
Query 131 FVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD 190
V +KA+ + ++A +RGE+ D + LPG ++ + + PPT + + +VD
Sbjct 133 VVGPKKAIATEMFRRAQERGELRDDLDLDLISSALPGIVLHHTFLLGEPPTTELIAKVVD 192
Query 191 DVILPSLTRS 200
+ILP++ R
Sbjct 193 QLILPAVIRG 202
>gi|118462932|ref|YP_882972.1| HTH-type transcriptional regulator [Mycobacterium avium 104]
gi|118164219|gb|ABK65116.1| putative HTH-type transcriptional regulator [Mycobacterium avium
104]
Length=90
Score = 107 bits (268), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 48/89 (54%), Positives = 69/89 (78%), Gaps = 0/89 (0%)
Query 113 VLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFR 172
+LVE+SR+ ALN+V+Q +F+ ++ L++ +LQQA+ RGEI ++ I++EL DLLPGYLIFR
Sbjct 1 MLVEISRDRALNNVMQDRFLHEQRTLVRQVLQQAISRGEIGASTINEELCDLLPGYLIFR 60
Query 173 SIIPNRPPTQDTVQALVDDVILPSLTRST 201
I NRPPT T++ LVD+ ILP L +T
Sbjct 61 CIFSNRPPTHLTIETLVDNAILPKLISAT 89
>gi|119717663|ref|YP_924628.1| TetR family transcriptional regulator [Nocardioides sp. JS614]
gi|119538324|gb|ABL82941.1| transcriptional regulator, TetR family [Nocardioides sp. JS614]
Length=215
Score = 106 bits (264), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 67/182 (37%), Positives = 103/182 (57%), Gaps = 8/182 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE E+L TL +L + GYDRLT+DAVAA A+ASKAT+YRRW +K LV+ A + + A
Sbjct 13 REQEILDATLEVLADVGYDRLTMDAVAARAKASKATLYRRWNNKVSLVIEA-LHSAKGPA 71
Query 81 VPPNTGNLRDDLLRLGELICREVG----QHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
P+TG LR DL + C G Q +T +VL ++R+ + + + V +
Sbjct 72 ELPDTGTLRGDLQG---VFCGMGGLVDPQSVATFASVLTAIARDADFAEAFRREVVGPKI 128
Query 137 ALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPS 196
A+ Q I ++A +RGE+ + A L L G ++ R + P +D + ++D +ILP+
Sbjct 129 AVSQEIWRRARERGEVCAEADLSLLEPALAGIVLHRVFVMGEQPDEDLITRVIDQIILPA 188
Query 197 LT 198
T
Sbjct 189 AT 190
>gi|256396574|ref|YP_003118138.1| TetR family transcriptional regulator [Catenulispora acidiphila
DSM 44928]
gi|256362800|gb|ACU76297.1| transcriptional regulator, TetR family [Catenulispora acidiphila
DSM 44928]
Length=228
Score = 105 bits (262), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 72/183 (40%), Positives = 101/183 (56%), Gaps = 12/183 (6%)
Query 19 SPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQ 78
+ R+ L L +L + GYDRLT+DAVAA A A KAT YRRW KAELV+ A R
Sbjct 20 ASRDDALCQAALEVLADVGYDRLTIDAVAARAGAGKATCYRRWAGKAELVVDAV---GRM 76
Query 79 VAVP--PNTGNLRDDLLRLGELICR-EVGQHA--STIRAVLVE-VSRNPALNDVLQHQFV 132
A P P+TG LR DL+ EL C G A + ++A LV + R+ L +V F+
Sbjct 77 KAQPELPDTGTLRGDLV---ELTCHFHEGDDAFRTDVQAGLVSGLVRDAKLREVFAEHFI 133
Query 133 DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDV 192
RK + + + +AV RGEI+ A D L D++P + + ++ R P V ++D +
Sbjct 134 APRKEVFRVVFDRAVARGEIAPVADYDLLSDVVPSMVFHQMMLTGRAPGPAFVHKVLDQI 193
Query 193 ILP 195
ILP
Sbjct 194 ILP 196
>gi|158317650|ref|YP_001510158.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158113055|gb|ABW15252.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=200
Score = 105 bits (261), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 65/191 (35%), Positives = 101/191 (53%), Gaps = 5/191 (2%)
Query 11 RPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLA 70
RP D S R+ + TL LL EHGYD +T+D VA A+A KAT+YRRWPSK LV+
Sbjct 14 RPRDES----RDGAIRQATLELLAEHGYDGVTMDRVATRAKAGKATIYRRWPSKVALVMD 69
Query 71 AFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLV-EVSRNPALNDVLQH 129
+ + Q P++G+LR +++ VG I A +V E+ RNP L ++
Sbjct 70 SITQFTEQTLQIPDSGSLRTEMILFLTAFHELVGSEQGRIMAEMVSEMPRNPELRAAVRE 129
Query 130 QFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALV 189
+ RK + + I+ + + RGEI+ A L ++ ++ R +I P ++ +V
Sbjct 130 RMWSQRKMMSEVIITRGIARGEITPEADPAILMEIGTALILQRLLITGDPVDSAFIEHVV 189
Query 190 DDVILPSLTRS 200
DDVI+ +R
Sbjct 190 DDVIIAYASRG 200
>gi|302552026|ref|ZP_07304368.1| TetR family transcriptional regulator [Streptomyces viridochromogenes
DSM 40736]
gi|302469644|gb|EFL32737.1| TetR family transcriptional regulator [Streptomyces viridochromogenes
DSM 40736]
Length=199
Score = 103 bits (258), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 68/182 (38%), Positives = 103/182 (57%), Gaps = 8/182 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL A L LL+E GYD LT+DAVAA R+SKAT+YR+W K ELV A
Sbjct 16 REAELYAAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGGKPELVAKAIRHNKPGNI 75
Query 81 VPPNTGNLRDDLLRLGELICRE----VGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
+TG+LR D L + RE + Q+A+ +R + + V NP L + ++
Sbjct 76 SDVDTGSLRGD---LHAITSREDDCTMQQNAALMRGLFMAVHSNPDLLQAFKELLIEPEM 132
Query 137 ALIQYILQQAVDRGEISSAAISDE-LWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
I+++AVDRGE+ + + E + +L G R++I ++PPTQ+ + + +D V+LP
Sbjct 133 EEFHRIVRRAVDRGEVRADCPALEYIVHMLVGAFATRTLIDDQPPTQEFLISYIDAVVLP 192
Query 196 SL 197
+L
Sbjct 193 AL 194
>gi|290959724|ref|YP_003490906.1| TetR family transcriptional regulator [Streptomyces scabiei 87.22]
gi|260649250|emb|CBG72364.1| putative TetR-family regulator [Streptomyces scabiei 87.22]
Length=200
Score = 103 bits (258), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 69/181 (39%), Positives = 102/181 (57%), Gaps = 5/181 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAF-IEGIRQV 79
RE EL A L LL+E GYD LT+DAVAA R+SKAT+YR+W KAELV A R
Sbjct 16 REAELYAAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGGKAELVAKAMRANKPRPD 75
Query 80 AVPPNTGNLRDDL--LRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKA 137
+TG+LR D+ L + + C + Q+++ +R + + + NP L + ++
Sbjct 76 FGSVDTGSLRGDMHALIMSQDDC-TIEQNSALMRGLAMAIHGNPDLLKAFRELIIEPELL 134
Query 138 LIQYILQQAVDRGEI-SSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPS 196
I+ +LQ+AVDRGEI D + + G + R +I PPTQ + + +D V+LP+
Sbjct 135 EIRGMLQRAVDRGEIREDNPAVDYVLHMFVGAFVARGMIDELPPTQAFIASYIDAVVLPA 194
Query 197 L 197
L
Sbjct 195 L 195
>gi|329941226|ref|ZP_08290505.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus
M045]
gi|329299757|gb|EGG43656.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus
M045]
Length=197
Score = 103 bits (257), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 67/182 (37%), Positives = 103/182 (57%), Gaps = 8/182 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GYD LT+DAVA +SKAT+YR+W KA+LV A +
Sbjct 17 REAELYTAVLDLLREVGYDALTMDAVAGRTHSSKATLYRQWGGKAQLVAKALRANKPGGS 76
Query 81 VPPNTGNLRDDLLRLGELICRE----VGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
+TG+LR D L L+ RE + Q+ + +R V + V NP L+ L+ V+
Sbjct 77 AAADTGSLRGD---LHALVVREDDCTMEQNHALMRGVAMAVHTNPDLHRALRELVVEPEL 133
Query 137 ALIQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
Q IL +A+DRGE+ + + + ++ G + R++I + PPTQ+ + + +D V+LP
Sbjct 134 VDFQRILDRAIDRGEVRADNPALRYMVHMVLGAFVTRALIDDLPPTQEFLHSYIDAVVLP 193
Query 196 SL 197
+L
Sbjct 194 AL 195
>gi|291439115|ref|ZP_06578505.1| tetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
gi|291342010|gb|EFE68966.1| tetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
Length=202
Score = 102 bits (255), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 70/187 (38%), Positives = 104/187 (56%), Gaps = 8/187 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GYD LT+DAVAA R+SKAT+YR+W KAELV+ A
Sbjct 19 REAELYRAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGGKAELVVKALRSQKPGSI 78
Query 81 VPPNTGNLRDDLLRLGELICRE----VGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
++G+LR D L +I RE + Q+ + +RA+ + V N L + V+
Sbjct 79 ADIDSGSLRGD---LHAIIAREDDCAMEQNVALMRALSMAVHMNDDLRQAFKELLVEPEI 135
Query 137 ALIQYILQQAVDRGEISSAAISDE-LWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
+ I++QA+DRGE+ + E + + G R++I + PPTQ + + +D V+LP
Sbjct 136 EEFRRIIRQAIDRGEVRPDNPALEYVTHMFVGAFATRTLIDDLPPTQRFLASYIDAVVLP 195
Query 196 SLTRSTG 202
+L STG
Sbjct 196 ALGVSTG 202
>gi|297560577|ref|YP_003679551.1| TetR family transcriptional regulator [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296845025|gb|ADH67045.1| transcriptional regulator, TetR family [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=224
Score = 102 bits (255), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 69/183 (38%), Positives = 103/183 (57%), Gaps = 4/183 (2%)
Query 19 SPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIR- 77
S R+ +L TL +L E G+ RLT+DAVAA A A KAT+YRRWPSK ELV+ A R
Sbjct 26 SSRDGAILDATLEVLAEAGFARLTMDAVAARAGAGKATLYRRWPSKTELVVDAVARMKRD 85
Query 78 --QVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEV-SRNPALNDVLQHQFVDH 134
P+TG+LR+DLL L G+ I A L + ++ A D + V
Sbjct 86 QVDTGSLPDTGDLREDLLGLFRPQSAREGERRLRIMAGLASMLVQDEASADAVSAAIVQP 145
Query 135 RKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVIL 194
+ ++++AV+RGE S+AA D L ++ +R+++ RP +D + +LVD V++
Sbjct 146 WAEAHRLLMRRAVERGEASAAADVDTLSQVVASMAAYRALVQRRPFDRDFLVSLVDGVLM 205
Query 195 PSL 197
P+L
Sbjct 206 PAL 208
>gi|152966002|ref|YP_001361786.1| TetR family transcriptional regulator [Kineococcus radiotolerans
SRS30216]
gi|151360519|gb|ABS03522.1| transcriptional regulator, TetR family [Kineococcus radiotolerans
SRS30216]
Length=234
Score = 100 bits (248), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 67/197 (35%), Positives = 105/197 (54%), Gaps = 11/197 (5%)
Query 11 RPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLA 70
RP DPS R+ +L +L E GY+ +T+ AVAA A A KAT++RRWP+K LVLA
Sbjct 41 RPRDPS----RDAAILGAAYDVLAETGYEDMTLSAVAARAGAGKATLHRRWPTKEALVLA 96
Query 71 --AFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVS---RNPALND 125
A + + P+TG+LR DLL L + +G AS +R + S +P L
Sbjct 97 VIAHVGPPPEARTLPDTGDLRSDLLAL--VDSAWLGGAASRLRGLKGLTSAALHSPRLAQ 154
Query 126 VLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTV 185
LQH+ V+ + +L++ RG+++ A L +++P R + + PP +
Sbjct 155 ALQHEVVEPYTEAYRGVLRRGAQRGQVAPDADVGTLAEIVPALATHRLLFADAPPERGYF 214
Query 186 QALVDDVILPSLTRSTG 202
+ ++DDV+LP+ R G
Sbjct 215 ETVIDDVLLPACARIPG 231
>gi|297200299|ref|ZP_06917696.1| TetR-family transcriptional regulator [Streptomyces sviceus ATCC
29083]
gi|197709413|gb|EDY53447.1| TetR-family transcriptional regulator [Streptomyces sviceus ATCC
29083]
Length=201
Score = 99.4 bits (246), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 67/187 (36%), Positives = 107/187 (58%), Gaps = 16/187 (8%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIE------ 74
RE EL L LL+E GYD +T+DAVAA R+SKAT+YR+W KAELV A
Sbjct 16 REAELYEAVLELLREVGYDAVTMDAVAARTRSSKATLYRQWGGKAELVARAVRHSKPGGM 75
Query 75 GIRQVAVPPNTGNLRDDL--LRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFV 132
G+ ++ +TG+LR DL L + C + Q+++ +R + + + NP L + +
Sbjct 76 GLDEI----DTGSLRGDLHALTMRSDDC-TMEQNSALMRGLAMAIHGNPDLLKAFREHLI 130
Query 133 DHRKALIQYILQQAVDRGEI--SSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVD 190
+ A + ++Q+A+DRGE+ + AI D + ++ G R++I PPTQ + + +D
Sbjct 131 EPETAEFRRLVQRAIDRGEVREDNPAI-DFMIHMMIGGFAARTMIDELPPTQAFLLSYID 189
Query 191 DVILPSL 197
V+LP+L
Sbjct 190 AVVLPAL 196
>gi|299138004|ref|ZP_07031184.1| transcriptional regulator, TetR family [Acidobacterium sp. MP5ACTX8]
gi|298599934|gb|EFI56092.1| transcriptional regulator, TetR family [Acidobacterium sp. MP5ACTX8]
Length=212
Score = 99.0 bits (245), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 59/169 (35%), Positives = 92/169 (55%), Gaps = 1/169 (0%)
Query 22 ETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAV 81
+ +LA T LL+E L+++A+A A K T+YR WPSKA + L A + +R+ V
Sbjct 24 QAAVLAATTELLKETSLRDLSIEAIARKAGVGKLTIYRWWPSKAYVALDAVMYSMRKNVV 83
Query 82 PPNTGNL-RDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ 140
PP+TG+ RD L L +I G T R +L E +P +V +F+ R+ +I+
Sbjct 84 PPDTGSAERDFALHLRSVIRFYTGPVGRTFRQLLAEGQNDPEFGEVFLQRFLMPRREVIE 143
Query 141 YILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALV 189
I ++ VDRG+I S D + DL+ G +IFR + + P + AL+
Sbjct 144 SIWKRGVDRGDIKSDLAMDTVLDLISGPMIFRLLTGHAPLSDAQADALI 192
>gi|333026382|ref|ZP_08454446.1| putative TetR family transcriptional regulator [Streptomyces
sp. Tu6071]
gi|332746234|gb|EGJ76675.1| putative TetR family transcriptional regulator [Streptomyces
sp. Tu6071]
Length=198
Score = 98.6 bits (244), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 70/202 (35%), Positives = 111/202 (55%), Gaps = 11/202 (5%)
Query 1 MVGAVTQIADRPTDPSPWSP-RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYR 59
M GAV R S +P RE EL L LL+E GY+ LT+DAVA+ R+SKAT+YR
Sbjct 1 MAGAVGATTRR----SRLTPEREAELYGAVLDLLREVGYEALTMDAVASRTRSSKATLYR 56
Query 60 RWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRL--GELICREVGQHASTIRAVLVEV 117
+W SK ELV+ A +TG+LR D + + CR + + A+ +R + +E+
Sbjct 57 QWGSKPELVVKALRHHKPHSIADIDTGSLRGDFHAMVGSQDDCR-MAEDAALMRGIAMEM 115
Query 118 SRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISS--AAISDELWDLLPGYLIFRSII 175
NP L+ + ++ + +L++AV+RGE+ + AI D + ++ G + R +I
Sbjct 116 KSNPDLHRAFRELLIEPEITGLAQVLRRAVERGEVDADRPAI-DFVVHMMVGAFVARQMI 174
Query 176 PNRPPTQDTVQALVDDVILPSL 197
RP +D + +D V+LP+L
Sbjct 175 DARPLDRDFLTRYIDAVVLPAL 196
>gi|295838290|ref|ZP_06825223.1| TetR-family transcriptional regulator [Streptomyces sp. SPB74]
gi|295826952|gb|EDY46575.2| TetR-family transcriptional regulator [Streptomyces sp. SPB74]
Length=194
Score = 97.8 bits (242), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 61/180 (34%), Positives = 102/180 (57%), Gaps = 4/180 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GY+ LT+DAVA+ R+SKAT+YR+W SK ELV+ A
Sbjct 14 REAELYGAVLDLLREVGYEALTMDAVASRTRSSKATLYRQWGSKPELVVKALRHHKPHSI 73
Query 81 VPPNTGNLRDDLLRL--GELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKAL 138
+TG+LR D + + CR + + A+ +R + +E+ NP L+ + ++
Sbjct 74 ADIDTGSLRGDFHAMVGSQDDCR-MAEDAALMRGIAMEMKSNPDLHRAFRELLIEPEITG 132
Query 139 IQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+ +L++AV+RGE+ + + D + ++ G + R +I RP +D + +D V+LP+L
Sbjct 133 LGQVLRRAVERGEVDADRPAIDYVVHMMVGAFVARQMIDARPLDRDFLTRYIDAVVLPAL 192
>gi|288916466|ref|ZP_06410843.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288352066|gb|EFC86266.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=200
Score = 97.8 bits (242), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 63/186 (34%), Positives = 96/186 (52%), Gaps = 5/186 (2%)
Query 11 RPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLA 70
RP D S R+ + L LL EHGYD +T+D VA A+A KAT+YRRWPSK LV+
Sbjct 14 RPRDES----RDHTIRQAALELLAEHGYDGVTMDRVATRAKAGKATIYRRWPSKIALVMD 69
Query 71 AFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRA-VLVEVSRNPALNDVLQH 129
A + Q ++R +L+ VG I A V+ E+ RNP L ++
Sbjct 70 ALTQFTEQTLQVAEADSMRKELVAFLSAFADLVGHAQGRIMAEVVSEMPRNPELRAAVRE 129
Query 130 QFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALV 189
+ + R + I+ + + RGE+ ++A + L ++ ++ R +I P V+ +V
Sbjct 130 RMWNQRMTTSEGIVNRGIARGEVGASADPNILVEVGTAMILQRLLITGDPVDGAFVEHIV 189
Query 190 DDVILP 195
DDVILP
Sbjct 190 DDVILP 195
>gi|302519804|ref|ZP_07272146.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78]
gi|318060925|ref|ZP_07979646.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actG]
gi|318078993|ref|ZP_07986325.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actF]
gi|302428699|gb|EFL00515.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78]
Length=194
Score = 97.4 bits (241), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 61/180 (34%), Positives = 102/180 (57%), Gaps = 4/180 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GY+ LT+DAVA+ R+SKAT+YR+W SK ELV+ A
Sbjct 14 REAELYGAVLDLLREVGYEALTMDAVASRTRSSKATLYRQWGSKPELVVKALRHHKPHSI 73
Query 81 VPPNTGNLRDDLLRL--GELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKAL 138
+TG+LR D + + CR + + A+ +R + +E+ NP L+ + ++
Sbjct 74 ADIDTGSLRGDFHAMVGSQDDCR-MAEDAALMRGIAMEMKSNPDLHRAFRELLIEPEITG 132
Query 139 IQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+ +L++AV+RGE+ + + D + ++ G + R +I RP +D + +D V+LP+L
Sbjct 133 LGQVLRRAVERGEVDADRPAIDFVVHMMVGAFVARQMIDARPLDRDFLTRYIDAVVLPAL 192
>gi|336179625|ref|YP_004585000.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
gi|334860605|gb|AEH11079.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
Length=201
Score = 94.7 bits (234), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 72/193 (38%), Positives = 106/193 (55%), Gaps = 13/193 (6%)
Query 11 RPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLA 70
RP D + RE +L L LL E GY+R+++ AVAA ARASKAT+YRRW K ELV
Sbjct 14 RPRDDA----REQAILHAALELLTEVGYERMSMVAVAARARASKATIYRRWAGKDELV-- 67
Query 71 AFIEGIRQVAVP----PNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNP-ALND 125
+E IR+ AV +TG+LR D++ + R + + + A +V R+ AL
Sbjct 68 --VEAIRRQAVDDIIIADTGSLRGDMIDIIRQKVRRLADGGAALMAGVVLAMRDSVALAS 125
Query 126 VLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTV 185
L+ Q ++ + L I+Q+AVDRGE S + +L+P + FR +I +
Sbjct 126 ALRAQMIEDGRGLAALIVQRAVDRGEPCSPTAACVFNELVPAAVFFRLLITGEALDDVFI 185
Query 186 QALVDDVILPSLT 198
LVDD++LP +T
Sbjct 186 HHLVDDILLPLMT 198
>gi|297202854|ref|ZP_06920251.1| transcriptional regulator [Streptomyces sviceus ATCC 29083]
gi|197717339|gb|EDY61373.1| transcriptional regulator [Streptomyces sviceus ATCC 29083]
Length=207
Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 61/188 (33%), Positives = 101/188 (54%), Gaps = 12/188 (6%)
Query 22 ETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAV 81
E +L L L G++ LT++ VAA A+ KA VYRRWPSK +LV A G+ +
Sbjct 24 ERAILDAALEQLSTVGWNGLTMEGVAAGAQTGKAAVYRRWPSKEDLVADALRAGLPRFEE 83
Query 82 PPNTGNLRDDLLRLGELICRE-----VGQHASTIRAVLVEVSRNPA--LNDVLQHQFVDH 134
P+ G +R+DLL L CR+ + S +R+V+ E + A + V+ + V+
Sbjct 84 APDLGGVREDLLEL----CRQAREAMFSRPGSALRSVIHECDQTQAERFHAVIFNGVVEP 139
Query 135 RKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVIL 194
L++ I+ + V RGE+ A +D ++D +P +++RS + V+ ++D +L
Sbjct 140 SVKLLRQIITRGVGRGEVRPDAANDYVFDAIPAMMMYRSKMRGSEWDDQDVEEMIDRFML 199
Query 195 PSLTRSTG 202
P L RS+G
Sbjct 200 P-LLRSSG 206
>gi|86739419|ref|YP_479819.1| TetR family transcriptional regulator [Frankia sp. CcI3]
gi|86566281|gb|ABD10090.1| transcriptional regulator, TetR family [Frankia sp. CcI3]
Length=383
Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/192 (33%), Positives = 97/192 (51%), Gaps = 5/192 (2%)
Query 4 AVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPS 63
A + RP D S R+ + TL LL E GYD +T+D VA ARA KAT+YRRWPS
Sbjct 192 ASSHPGGRPRDES----RDQAIRTATLDLLAEVGYDGVTMDRVATRARAGKATIYRRWPS 247
Query 64 KAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREV-GQHASTIRAVLVEVSRNPA 122
K LV+ A Q P+ G+LR D+L + G + ++ E+ RNP
Sbjct 248 KLALVMDAVNAFTEQRMPAPDNGSLRLDILEFLTSFHDAIRGDRGRILAELISEMPRNPG 307
Query 123 LNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQ 182
L D L+ R+A + I+++ + RGE+ L +L ++ R ++ P Q
Sbjct 308 LRDALRRGLWMQRQASSEAIIERGIARGEVRPDVDRTVLIELGTAVILQRVLLTGDPVDQ 367
Query 183 DTVQALVDDVIL 194
++ +VDD+++
Sbjct 368 TFLEMIVDDIVI 379
>gi|328883048|emb|CCA56287.1| Transcriptional regulator, TetR family [Streptomyces venezuelae
ATCC 10712]
Length=190
Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 67/182 (37%), Positives = 101/182 (56%), Gaps = 8/182 (4%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RETEL A L LL+E GYD LT+DAVAA +SKAT+YR+W SK ELV A
Sbjct 10 RETELYAAVLDLLREVGYDALTMDAVAARTHSSKATLYRQWGSKPELVARALRHNKPADL 69
Query 81 VPPNTGNLRDDLLRLGELICR----EVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRK 136
+TG+LR D EL+ R ++ + ++ +R + V NP L+ L+ ++
Sbjct 70 SQIDTGSLRGD---FRELLDRTDDCQMEKDSALMRGLAHAVHTNPELHRALRELLIEPEM 126
Query 137 ALIQYILQQAVDRGEISSAAISDELW-DLLPGYLIFRSIIPNRPPTQDTVQALVDDVILP 195
+ +L++AV RGE+ + + +L +L G + R +I ++P + A VD V+LP
Sbjct 127 NGLDEVLRRAVRRGEVDAGNPALKLVPHMLIGAFVARPLIEDQPVDHAFLVAYVDAVVLP 186
Query 196 SL 197
SL
Sbjct 187 SL 188
>gi|284034193|ref|YP_003384124.1| TetR family transcriptional regulator [Kribbella flavida DSM
17836]
gi|283813486|gb|ADB35325.1| transcriptional regulator, TetR family [Kribbella flavida DSM
17836]
Length=203
Score = 92.0 bits (227), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 71/188 (38%), Positives = 106/188 (57%), Gaps = 10/188 (5%)
Query 15 PSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIE 74
P RE E+L + ++ E GYDRLT+DAVA +A+ASKAT+YRRW +KAELV+ A I
Sbjct 13 PRIEGGREEEILDACVDIVAELGYDRLTMDAVATAAKASKATLYRRWSTKAELVVDA-IS 71
Query 75 GIRQVAVPP--NTGNLRDDLLRLGELICREVG----QHASTIRAVLVEVSRNPALNDVLQ 128
+ VP +TG+LR DL+ L C E G S +L + R+ L Q
Sbjct 72 RAKGCPVPDGVDTGSLRGDLIALA---CDEGGFTDEMPMSVTAGLLTALHRDDDLQRAFQ 128
Query 129 HQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQAL 188
+F+ R A++ + ++AV+RGEI + + L LP +I + + PT+D + +
Sbjct 129 ERFLKPRLAVVSQVYERAVERGEIGADVDVELLASTLPAVIIHHAFVLGVEPTEDLILRV 188
Query 189 VDDVILPS 196
+D VILP+
Sbjct 189 IDHVILPA 196
>gi|297193892|ref|ZP_06911290.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis
ATCC 25486]
gi|197720254|gb|EDY64162.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis
ATCC 25486]
Length=190
Score = 92.0 bits (227), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 62/179 (35%), Positives = 99/179 (56%), Gaps = 2/179 (1%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE +L L LL+E GYD LT+DAVAA R+SKAT+YR+W SK ELV A
Sbjct 10 REAQLYEAVLDLLREVGYDGLTMDAVAARTRSSKATLYRQWKSKPELVATALKHSKPVHV 69
Query 81 VPPNTGNLRDDL-LRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALI 139
+TG LR D +G ++ + ++ +R + + +P L++ L+ V+ +
Sbjct 70 GDIDTGTLRGDFHAMIGRTDDCQMEKDSALMRGLAQAIHAHPDLHEALRELLVEPEITGL 129
Query 140 QYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+L++AVDRGE+S+ + + +L G + R +I +R P Q + +D V+LP+L
Sbjct 130 DALLRRAVDRGEVSADNPALGYVPHMLVGAFVVRHLIEDRTPDQAFLTDYLDAVVLPAL 188
>gi|291453534|ref|ZP_06592924.1| TetR-family transcriptional regulator [Streptomyces albus J1074]
gi|291356483|gb|EFE83385.1| TetR-family transcriptional regulator [Streptomyces albus J1074]
Length=190
Score = 91.7 bits (226), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 66/186 (36%), Positives = 105/186 (57%), Gaps = 16/186 (8%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAA-------FI 73
RE EL L LL+E GYD LT+DAVAA A SKAT+YR+W SKAELV+ A F+
Sbjct 10 REGELYTAVLGLLREVGYDALTMDAVAARAHTSKATLYRQWGSKAELVVRALRCEKPVFL 69
Query 74 EGIRQVAVPPNTGNLRDDLLRLGELICRE-VGQHASTIRAVLVEVSRNPALNDVLQHQFV 132
+ + +TG+LR DL + E+ + + Q + +R ++ S + L+D L Q +
Sbjct 70 DEV-------DTGSLRGDLDAVLEMTDDDRLEQDTALMRGLMQAASASTELHDALISQLI 122
Query 133 DHRKALIQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDD 191
+ + +L++AVDRGE+++ + + ++ G L R +I NRP + ++ V
Sbjct 123 NPETDGVDTLLRRAVDRGEVAADNPALGYVPHMMIGALAARLLIENRPVDRAFLRHYVHS 182
Query 192 VILPSL 197
V+ P+L
Sbjct 183 VVFPAL 188
>gi|256392361|ref|YP_003113925.1| TetR family transcriptional regulator [Catenulispora acidiphila
DSM 44928]
gi|256358587|gb|ACU72084.1| transcriptional regulator, TetR family [Catenulispora acidiphila
DSM 44928]
Length=193
Score = 91.3 bits (225), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 59/186 (32%), Positives = 103/186 (56%), Gaps = 10/186 (5%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE +L TL LL EHGY+ L +DAVA+ A+ASKAT+YR WP KAELV+ A + Q
Sbjct 11 REQAILGATLDLLAEHGYEALRLDAVASRAKASKATLYRHWPGKAELVVDA-VRCYEQAD 69
Query 81 VPP--NTGNLRDDLL----RLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDH 134
+ +TG+LR D+L + +L+ E+GQ + ++ V ++P L V++ ++
Sbjct 70 LTDEVDTGSLRGDVLATLTAMRDLMSGELGQ---LMAGLVAAVQKDPELARVVRASMLED 126
Query 135 RKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVIL 194
++ + + +L +A+ RGE+ + ++ P + R + + + L DD+++
Sbjct 127 KQEVTRRMLDRAIARGELPADTDPTVFPEVAPAVMFMRIFLNAEHIDEAFLVHLTDDILI 186
Query 195 PSLTRS 200
P + R
Sbjct 187 PLMVRG 192
>gi|302560179|ref|ZP_07312521.1| TetR-family transcriptional regulator [Streptomyces griseoflavus
Tu4000]
gi|302477797|gb|EFL40890.1| TetR-family transcriptional regulator [Streptomyces griseoflavus
Tu4000]
Length=199
Score = 91.3 bits (225), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 68/180 (38%), Positives = 102/180 (57%), Gaps = 4/180 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GYD +T+DAVAA R+SKAT+YR+W KAELV+ A
Sbjct 16 REAELYRAVLDLLREVGYDAVTMDAVAARTRSSKATLYRQWGGKAELVVRAMRSQKPGGI 75
Query 81 VPPNTGNLRDDLLRLG--ELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKAL 138
+TG LR DL + E C + Q+A+ +RA+ + V +N L + V+
Sbjct 76 ADIDTGTLRGDLHAIAGREDDC-VMAQNAALMRALAMAVHQNDDLRQAFKDLLVEPEMEE 134
Query 139 IQYILQQAVDRGEISSAAIS-DELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+ ++++AVDRGEI + D + +L G R++I + PPTQ + + +D V+LP+L
Sbjct 135 FRRMIRRAVDRGEIRPDNPALDFMVHMLVGAFATRTLIDDLPPTQAFLTSYIDAVVLPAL 194
>gi|254388839|ref|ZP_05004071.1| TetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|294813133|ref|ZP_06771776.1| TetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|326441568|ref|ZP_08216302.1| TetR family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|197702558|gb|EDY48370.1| TetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|294325732|gb|EFG07375.1| TetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
Length=192
Score = 90.9 bits (224), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 63/179 (36%), Positives = 96/179 (54%), Gaps = 2/179 (1%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GY LT+DAVAA R+SKAT+YR+W SK +LV A
Sbjct 12 REVELFDAVLALLREVGYSALTMDAVAARTRSSKATLYRQWGSKPQLVATALQRCPPHGD 71
Query 81 VPPNTGNLRDDL-LRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALI 139
+ +TG+LR D L ++ Q + IR + V + L + LQ +F+ + +
Sbjct 72 IDIDTGSLRGDFHALLSHSDDAQMKQDSELIRGLFQAVHEDRDLYEALQERFIGPEISRL 131
Query 140 QYILQQAVDRGEISSAAISDEL-WDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
++ +AV RGE+ S + EL +L G R II ++ P ++ + +D V+LP+L
Sbjct 132 TEVVDRAVARGEVRSDNPARELAAHMLLGAFFTREIIDDQFPDREFLTRYIDSVVLPAL 190
>gi|295835609|ref|ZP_06822542.1| TetR family transcriptional regulator [Streptomyces sp. SPB74]
gi|197699314|gb|EDY46247.1| TetR family transcriptional regulator [Streptomyces sp. SPB74]
Length=205
Score = 90.9 bits (224), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 68/181 (38%), Positives = 97/181 (54%), Gaps = 3/181 (1%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE E L L +++E GY+ LT++ VAA A+ KAT+YR + SK LV AA
Sbjct 27 REDEFLDAALAVVRETGYEALTMEGVAARAQCGKATLYRLYGSKQRLVAAAVSRTRPAHR 86
Query 81 VPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQ 140
VP +TG+LR DLL E + + AV + AL+D L+ F+D A +
Sbjct 87 VPLDTGSLRGDLLAAARRAAAEFEDSTTLVWAVAHASIEDRALHDALRLAFIDPEAADLD 146
Query 141 YILQQAVDRGEISS-AAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTR 199
+ +A+ RGE+S A + L LL G + RS+ P+ ++ALVDDVILP+L
Sbjct 147 ATVDRALARGELSHRPAAARHLDGLLFGAALVRSLDGETAPSG--LEALVDDVILPALLH 204
Query 200 S 200
S
Sbjct 205 S 205
>gi|291436843|ref|ZP_06576233.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672]
gi|291339738|gb|EFE66694.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672]
Length=207
Score = 89.7 bits (221), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 59/189 (32%), Positives = 97/189 (52%), Gaps = 12/189 (6%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE +L L L G+ LTV+ VAA AR KA VYRRWPSK +LV A G +
Sbjct 23 RERAILDAALEQLSAVGWSGLTVEGVAAGARTGKAAVYRRWPSKEDLVADALRAGPPRFE 82
Query 81 VPPNTGNLRDDLLRLGELICRE-----VGQHASTIRAVLVEVSRNPA--LNDVLQHQFVD 133
P+ G++ +DLL ++CR Q +RAV+ E A + V+ VD
Sbjct 83 AAPDRGSVHEDLL----VLCRRARDAMFSQSGLAVRAVVHECDATQAERFHGVIFEGVVD 138
Query 134 HRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVI 193
+++ +++ +RGE+ A + ++D +P +++RS + T ++ ++D ++
Sbjct 139 PTLTMLREVIELGAERGEVRPDAANGYVFDAIPAMMMYRSKMCGSEWTDADLEEMIDRLM 198
Query 194 LPSLTRSTG 202
+P L RS G
Sbjct 199 VP-LLRSGG 206
>gi|182438110|ref|YP_001825829.1| TetR family transcriptional regulator [Streptomyces griseus subsp.
griseus NBRC 13350]
gi|326778755|ref|ZP_08238020.1| regulatory protein TetR [Streptomyces cf. griseus XylebKG-1]
gi|178466626|dbj|BAG21146.1| putative TetR-family transcriptional regulator [Streptomyces
griseus subsp. griseus NBRC 13350]
gi|326659088|gb|EGE43934.1| regulatory protein TetR [Streptomyces griseus XylebKG-1]
Length=190
Score = 89.7 bits (221), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 66/180 (37%), Positives = 96/180 (54%), Gaps = 4/180 (2%)
Query 21 RETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA 80
RE EL L LL+E GYD LT+DAVAA R+SKAT+YR+W SK ELV A
Sbjct 10 REAELYEAVLDLLREVGYDALTMDAVAARTRSSKATLYRQWGSKPELVAKALRHNKPGNL 69
Query 81 VPPNTGNLRDDL-LRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALI 139
+TG+LR D L ++ + A+ +R + V P L L+ ++
Sbjct 70 ADIDTGSLRGDFHTALSRTDDCQMEKDAALMRGLSHAVHEYPELLQALRELLIEPEMTGF 129
Query 140 QYILQQAVDRGEI--SSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSL 197
+LQ+A+DRGE+ + A+ + +L G L R +I +RP Q+ + VD V+LP+L
Sbjct 130 DQMLQRAMDRGELRPDNPALK-YIPHMLVGALAARQLIEDRPVDQEFLIDYVDSVVLPAL 188
>gi|297157805|gb|ADI07517.1| TetR family transcriptional regulator [Streptomyces bingchenggensis
BCW-1]
Length=207
Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 65/196 (34%), Positives = 102/196 (53%), Gaps = 3/196 (1%)
Query 3 GAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWP 62
GA+ + R + SP RE+EL + LL E GYD LT+DAVAA +SKAT+YR+W
Sbjct 6 GAMQALDRRRSRLSP--ERESELYGAVMGLLTEVGYDALTMDAVAARTHSSKATLYRQWK 63
Query 63 SKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPA 122
SK +LV A + +TG+LR DL + + + A+ +R + + +NP
Sbjct 64 SKPQLVATALRQTKPVSLENIDTGSLRGDLREMVRCGDQARERDAALMRGLALAAHQNPD 123
Query 123 LNDVLQHQFVDHRKALIQYILQQAVDRGEIS-SAAISDELWDLLPGYLIFRSIIPNRPPT 181
L + L+ V H + + +L +AVDRGE++ + +L G R ++ + P
Sbjct 124 LLEALRELMVKHELSAFETVLGRAVDRGEVAPDRPALRYIVHMLVGAFTTRLLVEAQEPD 183
Query 182 QDTVQALVDDVILPSL 197
+ +D VILP+L
Sbjct 184 AAYLFDYIDAVILPAL 199
Lambda K H
0.320 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 220408776486
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40