BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1557 Length=397 Score E Sequences producing significant alignments: (Bits) Value gi|15608695|ref|NP_216073.1| transmembrane transport protein Mmp... 787 0.0 gi|344219392|gb|AEN00023.1| transmembrane transport protein MmpL... 786 0.0 gi|289745312|ref|ZP_06504690.1| transmembrane transporter mmpL6 ... 785 0.0 gi|253799389|ref|YP_003032390.1| transmembrane transporter mmpL6... 783 0.0 gi|254364427|ref|ZP_04980473.1| transmembrane transport protein ... 778 0.0 gi|289750124|ref|ZP_06509502.1| transmembrane transporter mmpL6 ... 738 0.0 gi|31792742|ref|NP_855235.1| transmembrane transport protein Mmp... 738 0.0 gi|289443011|ref|ZP_06432755.1| MmpL6 protein [Mycobacterium tub... 738 0.0 gi|289447168|ref|ZP_06436912.1| MmpL6 protein [Mycobacterium tub... 738 0.0 gi|340626577|ref|YP_004745029.1| mmpl6 protein [Mycobacterium ca... 735 0.0 gi|254550577|ref|ZP_05141024.1| transmembrane transport protein ... 720 0.0 gi|289569594|ref|ZP_06449821.1| MmpL6 protein [Mycobacterium tub... 719 0.0 gi|240171021|ref|ZP_04749680.1| putative transmembrane transport... 624 1e-176 gi|342858163|ref|ZP_08714818.1| MmpL4 protein [Mycobacterium col... 595 5e-168 gi|296171262|ref|ZP_06852666.1| MmpL family membrane protein [My... 586 3e-165 gi|41409147|ref|NP_961983.1| MmpL2 [Mycobacterium avium subsp. p... 568 5e-160 gi|254776284|ref|ZP_05217800.1| MmpL4 protein [Mycobacterium avi... 568 8e-160 gi|296168054|ref|ZP_06850120.1| MmpL family membrane protein [My... 548 5e-154 gi|342859044|ref|ZP_08715698.1| MmpL4_7 [Mycobacterium colombien... 548 7e-154 gi|240169836|ref|ZP_04748495.1| MmpL family transport protein [M... 545 3e-153 gi|254819780|ref|ZP_05224781.1| MmpL4_7 [Mycobacterium intracell... 545 5e-153 gi|118462678|ref|YP_883823.1| MmpL4 protein [Mycobacterium avium... 543 3e-152 gi|41410045|ref|NP_962881.1| MmpL4_7 [Mycobacterium avium subsp.... 542 5e-152 gi|254777133|ref|ZP_05218649.1| MmpL4_7 [Mycobacterium avium sub... 541 5e-152 gi|336460142|gb|EGO39047.1| Transport protein [Mycobacterium avi... 532 4e-149 gi|41409849|ref|NP_962685.1| MmpL4_5 [Mycobacterium avium subsp.... 532 5e-149 gi|118470823|ref|YP_884795.1| transporter [Mycobacterium smegmat... 529 3e-148 gi|23345076|gb|AAN28686.1| putative membrane protein [Mycobacter... 529 4e-148 gi|333989520|ref|YP_004522134.1| transporter [Mycobacterium sp. ... 528 5e-148 gi|183980799|ref|YP_001849090.1| MmpL family transport protein [... 523 2e-146 gi|183980865|ref|YP_001849156.1| transmembrane transport protein... 523 2e-146 gi|169628084|ref|YP_001701733.1| membrane protein MmpL [Mycobact... 521 1e-145 gi|240171915|ref|ZP_04750574.1| transmembrane transport protein,... 520 2e-145 gi|296164371|ref|ZP_06846948.1| MmpL family membrane protein [My... 515 6e-144 gi|15839900|ref|NP_334937.1| MmpL family membrane protein [Mycob... 510 1e-142 gi|289749002|ref|ZP_06508380.1| transmembrane transporter mmpL2 ... 509 3e-142 gi|15607648|ref|NP_215021.1| transmembrane transport protein Mmp... 509 3e-142 gi|340625535|ref|YP_004743987.1| putative transmembrane transpor... 509 3e-142 gi|148821709|ref|YP_001286463.1| transmembrane transport protein... 509 4e-142 gi|31791689|ref|NP_854182.1| transmembrane transport protein Mmp... 508 1e-141 gi|121636425|ref|YP_976648.1| putative transmembrane transport p... 507 1e-141 gi|339630580|ref|YP_004722222.1| transporter [Mycobacterium afri... 507 1e-141 gi|118471014|ref|YP_884794.1| Mmp14a protein [Mycobacterium smeg... 506 2e-141 gi|296164398|ref|ZP_06846973.1| MmpL family membrane protein [My... 504 7e-141 gi|254819605|ref|ZP_05224606.1| MmpL4_2 [Mycobacterium intracell... 500 1e-139 gi|118467934|ref|YP_887800.1| MmpL4 protein [Mycobacterium smegm... 498 6e-139 gi|169631193|ref|YP_001704842.1| putative membrane protein MmpL ... 496 2e-138 gi|146760119|emb|CAJ77681.1| Mmpl4b protein [Mycobacterium chelo... 493 3e-137 gi|342858821|ref|ZP_08715476.1| Mmp14A protein [Mycobacterium co... 491 1e-136 gi|5524337|gb|AAD44230.1|AF143772_36 TmtpC [Mycobacterium avium] 489 3e-136 >gi|15608695|ref|NP_216073.1| transmembrane transport protein MmpL6 [Mycobacterium tuberculosis H37Rv] gi|15841024|ref|NP_336061.1| MmpL family membrane protein [Mycobacterium tuberculosis CDC1551] gi|148661353|ref|YP_001282876.1| transmembrane transport protein MmpL6 [Mycobacterium tuberculosis H37Ra] 42 more sequence titles Length=397 Score = 787 bits (2032), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/397 (99%), Positives = 397/397 (100%), Gaps = 0/397 (0%) Query 1 VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 +QGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS Sbjct 1 MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 Query 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG Sbjct 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 Query 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT Sbjct 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 Query 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ Sbjct 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 Query 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA Sbjct 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR Sbjct 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 Query 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 >gi|344219392|gb|AEN00023.1| transmembrane transport protein MmpL6 [Mycobacterium tuberculosis CTRI-2] Length=397 Score = 786 bits (2029), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/397 (99%), Positives = 396/397 (99%), Gaps = 0/397 (0%) Query 1 VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 +QGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS Sbjct 1 MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 Query 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG Sbjct 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 Query 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT Sbjct 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 Query 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ Sbjct 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 Query 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAM GTGGVVTAA Sbjct 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMVGTGGVVTAA 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR Sbjct 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 Query 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 >gi|289745312|ref|ZP_06504690.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis 02_1987] gi|289685840|gb|EFD53328.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis 02_1987] Length=397 Score = 785 bits (2028), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/397 (99%), Positives = 396/397 (99%), Gaps = 0/397 (0%) Query 1 VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 +QGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS Sbjct 1 MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 Query 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG Sbjct 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 Query 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQA HEAVKGTPMAGAGIYLAGTAAT Sbjct 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAGHEAVKGTPMAGAGIYLAGTAAT 180 Query 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ Sbjct 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 Query 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA Sbjct 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR Sbjct 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 Query 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 >gi|253799389|ref|YP_003032390.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN 1435] gi|289554652|ref|ZP_06443862.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN 605] gi|297634126|ref|ZP_06951906.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN 4207] gi|297731113|ref|ZP_06960231.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN R506] gi|313658445|ref|ZP_07815325.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN V2475] gi|253320892|gb|ACT25495.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN 1435] gi|289439284|gb|EFD21777.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis KZN 605] gi|328459139|gb|AEB04562.1| transmembrane transporter MmpL6 [Mycobacterium tuberculosis KZN 4207] Length=397 Score = 783 bits (2022), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/397 (99%), Positives = 395/397 (99%), Gaps = 0/397 (0%) Query 1 VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 +QGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS Sbjct 1 MQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIAS 60 Query 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG Sbjct 61 QQINRELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRG 120 Query 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAAT 180 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGA IYLAGTAAT Sbjct 121 LKLFLSADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGARIYLAGTAAT 180 Query 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ Sbjct 181 FKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQ 240 Query 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAA 300 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAM GTGGVVTAA Sbjct 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMVGTGGVVTAA 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR Sbjct 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 Query 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 361 PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 >gi|254364427|ref|ZP_04980473.1| transmembrane transport protein mmpL6 [Mycobacterium tuberculosis str. Haarlem] gi|134149941|gb|EBA41986.1| transmembrane transport protein mmpL6 [Mycobacterium tuberculosis str. Haarlem] Length=392 Score = 778 bits (2009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/392 (99%), Positives = 392/392 (100%), Gaps = 0/392 (0%) Query 6 VTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR 65 +TGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR Sbjct 1 MTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR 60 Query 66 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL 125 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL Sbjct 61 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL 120 Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ Sbjct 121 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 180 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI Sbjct 181 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 240 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA 305 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA Sbjct 241 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA 300 Query 306 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPAS 365 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPAS Sbjct 301 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPAS 360 Query 366 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 361 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR 392 >gi|289750124|ref|ZP_06509502.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis T92] gi|289690711|gb|EFD58140.1| transmembrane transporter mmpL6 [Mycobacterium tuberculosis T92] Length=967 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/388 (99%), Positives = 384/388 (99%), Gaps = 0/388 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL Sbjct 580 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 639 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 640 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 699 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 700 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 759 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 760 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 819 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS Sbjct 820 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 879 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 880 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 939 Query 370 PYGPRPVVRELLLREGNDDPRTQVATHR 397 PYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 940 PYGPRPVVRELLLREGNDDPRTQVATHR 967 Score = 60.5 bits (145), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 61/232 (27%), Positives = 108/232 (47%), Gaps = 13/232 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRW 352 GL A + F+ L +G +G++ L + PS+ +L R+ Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRF 351 >gi|31792742|ref|NP_855235.1| transmembrane transport protein MmpL6 [Mycobacterium bovis AF2122/97] gi|121637478|ref|YP_977701.1| putative transmembrane transport protein mmpL6 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989953|ref|YP_002644640.1| putative transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|31618332|emb|CAD96250.1| PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6 [Mycobacterium bovis AF2122/97] gi|121493125|emb|CAL71596.1| Probable conserved transmembrane transport protein mmpL6 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773066|dbj|BAH25872.1| putative transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341601496|emb|CCC64169.1| probable conserved transmembrane transport protein mmpL6 [Mycobacterium bovis BCG str. Moreau RDJ] Length=967 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/388 (99%), Positives = 384/388 (99%), Gaps = 0/388 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL Sbjct 580 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 639 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 640 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 699 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 700 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 759 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 760 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 819 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS Sbjct 820 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 879 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 880 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 939 Query 370 PYGPRPVVRELLLREGNDDPRTQVATHR 397 PYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 940 PYGPRPVVRELLLREGNDDPRTQVATHR 967 Score = 60.5 bits (145), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 61/232 (27%), Positives = 108/232 (47%), Gaps = 13/232 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRW 352 GL A + F+ L +G +G++ L + PS+ +L R+ Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRF 351 >gi|289443011|ref|ZP_06432755.1| MmpL6 protein [Mycobacterium tuberculosis T46] gi|289574241|ref|ZP_06454468.1| MmpL6 protein [Mycobacterium tuberculosis K85] gi|289753644|ref|ZP_06513022.1| MmpL6 protein [Mycobacterium tuberculosis EAS054] 6 more sequence titles Length=967 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/388 (99%), Positives = 384/388 (99%), Gaps = 0/388 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL Sbjct 580 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 639 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 640 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 699 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 700 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 759 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 760 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 819 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS Sbjct 820 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 879 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 880 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 939 Query 370 PYGPRPVVRELLLREGNDDPRTQVATHR 397 PYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 940 PYGPRPVVRELLLREGNDDPRTQVATHR 967 Score = 60.5 bits (145), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 61/232 (27%), Positives = 108/232 (47%), Gaps = 13/232 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRW 352 GL A + F+ L +G +G++ L + PS+ +L R+ Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRF 351 >gi|289447168|ref|ZP_06436912.1| MmpL6 protein [Mycobacterium tuberculosis CPHL_A] gi|289420126|gb|EFD17327.1| MmpL6 protein [Mycobacterium tuberculosis CPHL_A] Length=966 Score = 738 bits (1905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/388 (99%), Positives = 384/388 (99%), Gaps = 0/388 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL Sbjct 579 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 638 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 639 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 698 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 699 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 758 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 759 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 818 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS Sbjct 819 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 878 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 879 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 938 Query 370 PYGPRPVVRELLLREGNDDPRTQVATHR 397 PYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 939 PYGPRPVVRELLLREGNDDPRTQVATHR 966 Score = 62.0 bits (149), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 63/242 (27%), Positives = 112/242 (47%), Gaps = 13/242 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVR 360 GL A + F+ L +G +G++ L + PS+ +L R+ + + R Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRFGCFEPKRR 359 Query 361 PR 362 R Sbjct 360 MR 361 >gi|340626577|ref|YP_004745029.1| mmpl6 protein [Mycobacterium canettii CIPT 140010059] gi|340004767|emb|CCC43911.1| mmpl6 protein [Mycobacterium canettii CIPT 140010059] Length=967 Score = 735 bits (1897), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/388 (98%), Positives = 383/388 (99%), Gaps = 0/388 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPD+IASQQINRELAL Sbjct 580 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDQIASQQINRELAL 639 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 640 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 699 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 700 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 759 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 760 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 819 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAAT S Sbjct 820 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATTS 879 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 880 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 939 Query 370 PYGPRPVVRELLLREGNDDPRTQVATHR 397 PYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 940 PYGPRPVVRELLLREGNDDPRTQVATHR 967 Score = 60.5 bits (145), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 61/232 (27%), Positives = 108/232 (47%), Gaps = 13/232 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRW 352 GL A + F+ L +G +G++ L + PS+ +L R+ Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRF 351 >gi|254550577|ref|ZP_05141024.1| transmembrane transport protein mmpL6 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=391 Score = 720 bits (1859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/392 (97%), Positives = 382/392 (98%), Gaps = 1/392 (0%) Query 6 VTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR 65 +TGLVKR VFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR Sbjct 1 MTGLVKRAG-CEIVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINR 59 Query 66 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL 125 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL Sbjct 60 ELALANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFL 119 Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ Sbjct 120 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 179 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI Sbjct 180 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 239 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA 305 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA Sbjct 240 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFA 299 Query 306 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPAS 365 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV + FWWPQRVRPRPAS Sbjct 300 ATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVRIPPRFWWPQRVRPRPAS 359 Query 366 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR 397 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR Sbjct 360 RMLRPYGPRPVVRELLLREGNDDPRTQVATHR 391 >gi|289569594|ref|ZP_06449821.1| MmpL6 protein [Mycobacterium tuberculosis T17] gi|289543348|gb|EFD46996.1| MmpL6 protein [Mycobacterium tuberculosis T17] Length=967 Score = 719 bits (1857), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/387 (97%), Positives = 376/387 (98%), Gaps = 0/387 (0%) Query 10 VKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 69 + W +RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL Sbjct 580 IPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELAL 639 Query 70 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 129 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG Sbjct 640 ANYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG 699 Query 130 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 189 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT Sbjct 700 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGAT 759 Query 190 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 249 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW Sbjct 760 YDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYW 819 Query 250 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 309 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS Sbjct 820 IVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMS 879 Query 310 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 369 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR Sbjct 880 SFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLR 939 Query 370 PYGPRPVVRELLLREGNDDPRTQVATH 396 YGPRP + EL LREG DDPRTQ TH Sbjct 940 QYGPRPKISELFLREGKDDPRTQETTH 966 Score = 60.1 bits (144), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 61/232 (27%), Positives = 108/232 (47%), Gaps = 13/232 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQ-AAHEAVKGTPMAGAGIYLAGTAATFKD- 183 S DGKAA + + G+ I +DA++ AH P AG Y+ G A D Sbjct 128 STDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP----PPAGVKAYVTGAAPLMADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-L 242 Q G+ + GI L +I ++++ + RS+V ++++ TV + L A+ G+ + + Sbjct 184 FQVGSKGTAKVTGIT-LVVIAVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 +G+ Y L +L++A G+DY + ++ R+ E A + T GT VV + Sbjct 243 IGLSTY--STNLLTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRW 352 GL A + F+ L +G +G++ L + PS+ +L R+ Sbjct 301 GLTVAGAVYCLSFTRLPYFQSLGIPASIGVMI-ALAAALSLAPSVLILGSRF 351 >gi|240171021|ref|ZP_04749680.1| putative transmembrane transport protein [Mycobacterium kansasii ATCC 12478] Length=959 Score = 624 bits (1608), Expect = 1e-176, Method: Compositional matrix adjust. Identities = 303/360 (85%), Positives = 331/360 (92%), Gaps = 0/360 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W RS FD IDGID+L +QL SV TLDKL AIQPQL+AL+PD+IASQQ N +L L+NY+ Sbjct 584 WAARSAFDAIDGIDRLSDQLESVRKTLDKLDAIQPQLLALIPDQIASQQANHDLTLSNYS 643 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+SGIY QTAA+ EN+ AMGQAFDAAKNDD FYLPPEAF+NPDF+RGL++FLS DGKAAR Sbjct 644 TISGIYDQTAAMTENSTAMGQAFDAAKNDDFFYLPPEAFNNPDFKRGLQMFLSPDGKAAR 703 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 MIISHEGDPATPEGISH+D IK+AA EAVKGTP+ + IYLAGTA T+KDIQDGA YDL+ Sbjct 704 MIISHEGDPATPEGISHVDPIKKAAREAVKGTPLQASKIYLAGTAPTYKDIQDGAKYDLM 763 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAALSLILLIMMI+TRSLVAA+VIVGTVALSLGASFGLSVLVWQH+ GIQLYWIVLA Sbjct 764 IAGIAALSLILLIMMIVTRSLVAAIVIVGTVALSLGASFGLSVLVWQHIFGIQLYWIVLA 823 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 LAVI+LL VGSDYNLLLISR KEEIGAGLNTGIIRAM G+GGVVTAAGLVFAATMSSFVF Sbjct 824 LAVIVLLGVGSDYNLLLISRLKEEIGAGLNTGIIRAMGGSGGVVTAAGLVFAATMSSFVF 883 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLRVLGQIGTTIGLGLLFDTL+VR+FMTPSIA LLGRWFWWPQRVRPRPASRMLRPYGP Sbjct 884 SDLRVLGQIGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPQRVRPRPASRMLRPYGP 943 Score = 47.8 bits (112), Expect = 0.003, Method: Compositional matrix adjust. Identities = 60/260 (24%), Positives = 111/260 (43%), Gaps = 30/260 (11%) Query 125 LSADGKAARMIISHEGDPATPEGISHID---AIKQAAHEAVKGTPMAGAGI--------- 172 LS D K + GDP T G+ D A Q +G +A + Sbjct 103 LSQDTKHVEHVQDFWGDPLTAAGVQSTDGKAAYVQVYLAGNQGEALANESVAAVRDIVAH 162 Query 173 ---------YLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGT 223 Y+ G A D + + + L +I +++ + RS+V +++ T Sbjct 163 TPPPNRMKAYVTGAAPLLADQFGVGSKGTVKVTLITLLVIAVMLFFVYRSVVTMFLVLLT 222 Query 224 VALSLGASFGL-SVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGL 282 V + L A+ G+ ++L ++G+ +Y L +L++A G+DY + + R++E G G Sbjct 223 VLVQLLAARGIIALLADSGIIGLSVY--ATNLLTLLVIAAGTDYAIFFVGRYQEARGTGE 280 Query 283 NTGII--RAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAF 340 + G GT +V +GL A + F+ L +G + +G+L L Sbjct 281 DQGTAFHTMFHGTAHIVLGSGLTIAGAVYCLSFTRLPYFQSLGVPVAIGILV-ALTAALT 339 Query 341 MTPSIAVLLGRWF--WWPQR 358 +TP++ + +G F + P+R Sbjct 340 LTPAV-LTIGSHFGLFEPKR 358 >gi|342858163|ref|ZP_08714818.1| MmpL4 protein [Mycobacterium colombiense CECT 3035] gi|342133867|gb|EGT87047.1| MmpL4 protein [Mycobacterium colombiense CECT 3035] Length=966 Score = 595 bits (1533), Expect = 5e-168, Method: Compositional matrix adjust. Identities = 298/373 (80%), Positives = 339/373 (91%), Gaps = 1/373 (0%) Query 17 RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMS 76 RS+FD +DGIDQL E+ ++T +LD+L A+QP+L AL+P +I SQQ NR+L LANYAT+S Sbjct 587 RSLFDALDGIDQLTEKFENLTASLDQLDALQPKLTALIPPQIQSQQTNRDLTLANYATLS 646 Query 77 GIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMII 136 GIYAQTAA I+NA A+G+AFDAAKNDD+FYLPPE F+NPDF+RGLKLFLS DGKAARMI+ Sbjct 647 GIYAQTAAAIDNATALGRAFDAAKNDDTFYLPPEVFNNPDFKRGLKLFLSPDGKAARMIV 706 Query 137 SHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAG 196 +HEGDPATPEGISHID I +AAHEA+KGTPMAGAGIY+ GTAAT+KDIQDGA YDL+I Sbjct 707 THEGDPATPEGISHIDPITKAAHEALKGTPMAGAGIYVGGTAATYKDIQDGAKYDLMIVA 766 Query 197 IAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAV 256 AALSLILLIMMIITRSL+AALVIVGTVALSLGASFGLSVLVWQ++ GIQLYW+VLALAV Sbjct 767 FAALSLILLIMMIITRSLIAALVIVGTVALSLGASFGLSVLVWQYIFGIQLYWVVLALAV 826 Query 257 ILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDL 316 ILLLAVGSDYNLLLISRFKEEI AGLNTGIIRAMAG+G VVT+AG+VFA TM +FVFS Sbjct 827 ILLLAVGSDYNLLLISRFKEEIHAGLNTGIIRAMAGSGSVVTSAGIVFAVTMCAFVFSGF 886 Query 317 RVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPV 376 +VLGQIGTTIGLGLLFDTL+VR+FMTPS+A LLGRWFWWPQRVRPRPAS MLRPYGPRP Sbjct 887 QVLGQIGTTIGLGLLFDTLIVRSFMTPSVARLLGRWFWWPQRVRPRPASTMLRPYGPRPA 946 Query 377 VRELLLREGNDDP 389 VR+LLL + +DDP Sbjct 947 VRQLLLWD-DDDP 958 Score = 60.5 bits (145), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 51/212 (25%), Positives = 96/212 (46%), Gaps = 14/212 (6%) Query 126 SADGKAARMIIS---HEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFK 182 S+DGKAA + ++ ++G EG+ + I + + P G Y+ G A Sbjct 128 SSDGKAAYVQVNLAGNQGSALANEGVGALRDIIE------RMKPPPGVKTYVTGAAPLIS 181 Query 183 DIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH- 241 D D + + +I L++ + RS++ L+++ TV + + A+ GL + Sbjct 182 DQFDVGSKGTAKVTAITVGVIALMLFFVYRSVLTTLLVLATVLIEMSAARGLVAFLGNAG 241 Query 242 LLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTA 299 ++G+ Y L +L++A G+DY + + R++E G G + GT +V Sbjct 242 VIGLSTY--ATNLLTLLVIAAGTDYAIFFVGRYQEARGTGEDREKAFYTMYHGTTHIVLG 299 Query 300 AGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 +GL A ++ F+ L +G LG+L Sbjct 300 SGLTVAGAVACLSFTRLPYFQSLGIPAALGIL 331 >gi|296171262|ref|ZP_06852666.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894230|gb|EFG73987.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=524 Score = 586 bits (1510), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 293/371 (79%), Positives = 335/371 (91%), Gaps = 0/371 (0%) Query 17 RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMS 76 RS+FD +DGIDQL E+ +T +LDKL A+QP+LVAL+P +I SQQ NR+L LANYAT+S Sbjct 146 RSLFDALDGIDQLTEKFEGLTASLDKLDALQPKLVALIPPQIDSQQTNRDLTLANYATLS 205 Query 77 GIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMII 136 GIYAQTAA I+NA A+G+AFDAAKNDD+FYLPP+ F+NPDF+RGLKLFLS DGKAARMI+ Sbjct 206 GIYAQTAAAIDNATALGRAFDAAKNDDTFYLPPDVFNNPDFKRGLKLFLSPDGKAARMIV 265 Query 137 SHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAG 196 +HEGDPATPEGISHID + +AA EA+KGTPMAGAGIYL GTA+T+KDIQDGA YDL+I Sbjct 266 THEGDPATPEGISHIDPMAKAAREALKGTPMAGAGIYLGGTASTYKDIQDGAKYDLMIVA 325 Query 197 IAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAV 256 AALSLILLIMMIITRSL+AALVIVGTVA+SLGASFGLSVLVWQ+L GIQLYW+VLALAV Sbjct 326 FAALSLILLIMMIITRSLIAALVIVGTVAMSLGASFGLSVLVWQYLFGIQLYWVVLALAV 385 Query 257 ILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDL 316 ILLLAVGSDYNLLLISRFKEEI AGLNT IIRAMAG+G VVT+AG+VFA TM +FVFS Sbjct 386 ILLLAVGSDYNLLLISRFKEEIHAGLNTCIIRAMAGSGSVVTSAGIVFAVTMCAFVFSGF 445 Query 317 RVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPV 376 +VLGQIGTTIGLGLLFDTL+VR+FMTPS+A +LGRWFWWPQRVRPRPAS MLRPYGPRP Sbjct 446 QVLGQIGTTIGLGLLFDTLIVRSFMTPSVAKILGRWFWWPQRVRPRPASTMLRPYGPRPA 505 Query 377 VRELLLREGND 387 VR+LLL + +D Sbjct 506 VRQLLLWDDDD 516 >gi|41409147|ref|NP_961983.1| MmpL2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118464293|ref|YP_883026.1| MmpL4 protein [Mycobacterium avium 104] gi|41397967|gb|AAS05597.1| MmpL2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118165580|gb|ABK66477.1| MmpL4 protein [Mycobacterium avium 104] gi|336459174|gb|EGO38121.1| Transport protein [Mycobacterium avium subsp. paratuberculosis S397] Length=972 Score = 568 bits (1464), Expect = 5e-160, Method: Compositional matrix adjust. Identities = 283/371 (77%), Positives = 320/371 (87%), Gaps = 0/371 (0%) Query 17 RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMS 76 RSVFD +DGID+L Q +T +LDKL A Q +LV LLP +IA Q+ N L L+NYAT Sbjct 586 RSVFDALDGIDELSAQFEKLTASLDKLDAGQQKLVTLLPPQIADQEKNLALTLSNYATNL 645 Query 77 GIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMII 136 GI AQT A + A A+GQA+DAAKNDDSFYLPPEAF NP+F+RGLKLFLS DGKAARMII Sbjct 646 GINAQTRANTDTATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMII 705 Query 137 SHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAG 196 SHEGDPATPEGISHI+ I+ AA +AVK TP+ + IYLAGTAAT+KDI +GA YDLLIAG Sbjct 706 SHEGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAG 765 Query 197 IAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAV 256 IAALSLILLIM++ITRSLVAA+VIVGTVALSLGASFGLSVLVWQ +LGI+LYWI LAL+V Sbjct 766 IAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKLYWICLALSV 825 Query 257 ILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDL 316 I+LLAVGSDYNLLLISRF+EEI AGLNTGIIR+MAG+G VVT+AGLVFA TM+SFV + L Sbjct 826 IILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGAVVTSAGLVFAFTMASFVSASL 885 Query 317 RVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPV 376 VLGQIGTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQRVRPRPAS MLRPYGPRP Sbjct 886 LVLGQIGTTIALGLLFDTLIVRSFMTPSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPA 945 Query 377 VRELLLREGND 387 VR+LLL E D Sbjct 946 VRQLLLWEDGD 956 >gi|254776284|ref|ZP_05217800.1| MmpL4 protein [Mycobacterium avium subsp. avium ATCC 25291] Length=948 Score = 568 bits (1463), Expect = 8e-160, Method: Compositional matrix adjust. Identities = 283/371 (77%), Positives = 320/371 (87%), Gaps = 0/371 (0%) Query 17 RSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMS 76 RSVFD +DGID+L Q +T +LDKL A Q +LV LLP +IA Q+ N L L+NYAT Sbjct 562 RSVFDALDGIDELSAQFEKLTASLDKLDAGQQKLVTLLPPQIADQEKNLALTLSNYATNL 621 Query 77 GIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMII 136 GI AQT A + A A+GQA+DAAKNDDSFYLPPEAF NP+F+RGLKLFLS DGKAARMII Sbjct 622 GINAQTRANTDTATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMII 681 Query 137 SHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAG 196 SHEGDPATPEGISHI+ I+ AA +AVK TP+ + IYLAGTAAT+KDI +GA YDLLIAG Sbjct 682 SHEGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAG 741 Query 197 IAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAV 256 IAALSLILLIM++ITRSLVAA+VIVGTVALSLGASFGLSVLVWQ +LGI+LYWI LAL+V Sbjct 742 IAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKLYWICLALSV 801 Query 257 ILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDL 316 I+LLAVGSDYNLLLISRF+EEI AGLNTGIIR+MAG+G VVT+AGLVFA TM+SFV + L Sbjct 802 IILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGAVVTSAGLVFAFTMASFVSASL 861 Query 317 RVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPV 376 VLGQIGTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQRVRPRPAS MLRPYGPRP Sbjct 862 LVLGQIGTTIALGLLFDTLIVRSFMTPSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPA 921 Query 377 VRELLLREGND 387 VR+LLL E D Sbjct 922 VRQLLLWEDGD 932 >gi|296168054|ref|ZP_06850120.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896861|gb|EFG76489.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=976 Score = 548 bits (1412), Expect = 5e-154, Method: Compositional matrix adjust. Identities = 260/376 (70%), Positives = 312/376 (83%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DGID + + + ++ LDKL IQP+LV L+P +I SQQ N + ++NYA Sbjct 593 WALRSLFDALDGIDAVSDNIEKLSANLDKLDQIQPRLVELIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S DG A R Sbjct 653 TTRGLNDQAKAQSDNATAEGDAFDRAKNDDTFYLPPEAFKSPDFARGLKQFISPDGHAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPATPEG++HID IKQA HEA+KGTP GA +YL GTAAT+KD++DG+ DL+ Sbjct 713 LIISHEGDPATPEGVNHIDPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMRDGSNMDLM 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRSLVAA VIVGTV LSLGASFGLSVL+WQ++LGI L+W+VLA Sbjct 773 IAGIAATTLIFVIMLVITRSLVAAFVIVGTVLLSLGASFGLSVLLWQYILGINLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +A+ILLLAVGSDYNLLLISRFKEEI AGL TGIIRA+AG+G VVT+AGLVFAATM++F F Sbjct 833 MAIILLLAVGSDYNLLLISRFKEEIHAGLRTGIIRAVAGSGSVVTSAGLVFAATMATFAF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S LRV+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLRVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 RP VRELLL+ + P Sbjct 953 RPAVRELLLKNVEEHP 968 Score = 51.2 bits (121), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 45/209 (22%), Positives = 90/209 (44%), Gaps = 8/209 (3%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S D KAA + + G +A+++ ++V P G Y+ G D Sbjct 137 SHDQKAAYVQVYLSGRMGGSLATESTEAVRKIV-DSVPAPP--GIKAYVTGAGPLIADQS 193 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQH-LLG 244 + I + + +I+++++I+ RS+ ++++ V + L A+ G+ + + ++G Sbjct 194 HAGEKGIAIVTMVTILVIIVMLLIVYRSVSTVMIMLAMVFIELAAARGVVATLGNYGIMG 253 Query 245 IQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAG--LNTGIIRAMAGTGGVVTAAGL 302 + + + V+L +A +DY + ++ R+ E G G GT VV +GL Sbjct 254 LSTF--ANNMLVLLAIAASTDYAIFIVGRYHEARGLGETREKAFYTMFHGTAHVVLGSGL 311 Query 303 VFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 A M F L +G +G+L Sbjct 312 TIAGAMYCLSFCRLPYFQTMGVPCAVGML 340 >gi|342859044|ref|ZP_08715698.1| MmpL4_7 [Mycobacterium colombiense CECT 3035] gi|342133285|gb|EGT86488.1| MmpL4_7 [Mycobacterium colombiense CECT 3035] Length=976 Score = 548 bits (1411), Expect = 7e-154, Method: Compositional matrix adjust. Identities = 259/376 (69%), Positives = 314/376 (84%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVF+ +DGIDQ+ E + +++ LDKL IQP+LVAL+P +I SQQ N + ++NYA Sbjct 593 WALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S DG+A R Sbjct 653 ITQGLNEQARAQSDNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKQFISPDGRAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPA+PEGI HI+ IKQA HEA+KGTP GA +YL GTAAT+KD+ DG+ DLL Sbjct 713 LIISHEGDPASPEGIKHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLL 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRS+VAA VIVGTV LSLGASFGLSVL+WQ++LG++L+W+VLA Sbjct 773 IAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYILGLKLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +AVILLLAVGSDYNLLLISRFKEEI AGL TG IRAMAG+G VVT+AGLVFAATM++F+F Sbjct 833 MAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S L V+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 RP VREL+L + ++ P Sbjct 953 RPAVRELILNDVDEHP 968 Score = 51.6 bits (122), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/184 (22%), Positives = 81/184 (45%), Gaps = 6/184 (3%) Query 156 QAAHEAVKGTPMA-GAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSL 214 +A + V P G Y+ G F D + + ++I+L+++ + RS+ Sbjct 163 EAVRKIVNSVPAPPGIKAYVTGAGPLFADQSHAGEKGVAKVTLVTFAVIILMLLFVYRSV 222 Query 215 VAALVIVGTVALSLGASFGLSVLVWQH-LLGIQLYWIVLALAVILLLAVGSDYNLLLISR 273 + L+++ V + L A+ G+ ++ + ++G+ + + V++ +A G+DY + ++ R Sbjct 223 ITMLIMLVMVFVELAAARGVVAVLGNYGVIGLSTF--ANNMLVLMAIAAGTDYAIFVVGR 280 Query 274 FKEEIGAGLN--TGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 + E G G + T VV +GL A M F L +G +G+L Sbjct 281 YHEARGLGESREKAFYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFESLGVPCAVGML 340 Query 332 FDTL 335 L Sbjct 341 VAVL 344 >gi|240169836|ref|ZP_04748495.1| MmpL family transport protein [Mycobacterium kansasii ATCC 12478] Length=992 Score = 545 bits (1405), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 258/386 (67%), Positives = 324/386 (84%), Gaps = 2/386 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG+DQ+ E+LA ++ LD+L + PQ++A LP +IA+ + + + L ++ Sbjct 599 WSLRSIFDALDGLDQIDEKLAELSGNLDQLDVLMPQMLAQLPPQIATMKTMKTMMLTMHS 658 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 +MS +Y Q + +N+ AMGQAFDA++NDDSFY+PPE FDNPDF+RGLK+FLS DG A R Sbjct 659 SMSSLYDQMDEMSKNSTAMGQAFDASRNDDSFYIPPEVFDNPDFKRGLKMFLSPDGHAVR 718 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISHEGDPATPEGISH++ I +AA EA+KGTP+ GA IYL GTAA FKD++DG+ +DL+ Sbjct 719 FIISHEGDPATPEGISHVEPILKAAKEAIKGTPLEGAKIYLGGTAAVFKDMRDGSKWDLM 778 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA SLI +IM++ITRS+VAA IVGTV LSLGASFGLSVLVWQ +LG +L+W+VLA Sbjct 779 IAGIAAASLIFIIMLVITRSVVAAFTIVGTVLLSLGASFGLSVLVWQDILGFELHWMVLA 838 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLL+SRFKEEIGAG+ TGIIR+MAGTG VVT+AGLVFAATM+SFVF Sbjct 839 MSVILLLAVGSDYNLLLVSRFKEEIGAGIKTGIIRSMAGTGAVVTSAGLVFAATMASFVF 898 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDL+V+GQ+GTTI LGLLFDTL+VR+FM PS+A L+GRWFWWPQRVR RPAS++LRPYGP Sbjct 899 SDLKVIGQVGTTIALGLLFDTLIVRSFMMPSVAALMGRWFWWPQRVRTRPASQLLRPYGP 958 Query 374 RPVVRELLL-REGND-DPRTQVATHR 397 RP+VR LLL R+G +P T R Sbjct 959 RPLVRALLLPRDGKSANPSGTADTDR 984 Score = 52.0 bits (123), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 59/231 (26%), Positives = 107/231 (47%), Gaps = 10/231 (4%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S DGKAA + ++ G+ ++A+++ ++V P G Y+ G AA D Sbjct 143 SPDGKAAYVQLNLAGNQGESLANESVEAVRKIV-DSVPAPP--GVKAYVTGAAALTADQS 199 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 + + +I+++++ + RS+V L+++ V + L A+ + V H I Sbjct 200 TSGDKGVKKVTMITFLVIIVMLLFVYRSIVQVLLVLVMVGIELMAARQV-VAFLGHYNII 258 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAGLV 303 L + L V++ +A G+DY + ++ R++E G G + GT VV +GL Sbjct 259 GLSTFAVNLLVLMAIAAGTDYAIFVLGRYQEARGLGEDREKAFYTMFHGTAHVVLGSGLT 318 Query 304 FAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVL-LGRWF 353 A M F+ L +G +G+L + V A +T AVL +G +F Sbjct 319 IAGAMYCLSFTRLPYFQTLGAPCAIGML---VAVLAALTLGPAVLVVGSYF 366 >gi|254819780|ref|ZP_05224781.1| MmpL4_7 [Mycobacterium intracellulare ATCC 13950] Length=976 Score = 545 bits (1404), Expect = 5e-153, Method: Compositional matrix adjust. Identities = 258/376 (69%), Positives = 314/376 (84%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVF+ +DGIDQ+ E + +++ LDKL IQP+LVAL+P +I SQQ N + ++NYA Sbjct 593 WALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S +G A R Sbjct 653 ITQGLNEQAKAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKQFISPNGHAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPATPEGI+HI+ IKQA HEA+KGTP GA +YL GTAAT+KD+ DG+ DL+ Sbjct 713 LIISHEGDPATPEGINHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSDIDLI 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRS+VAA+VIVGTV LSLGASFGLSVL+WQ++LG++L+W+VLA Sbjct 773 IAGIAAATLIFVIMLVITRSVVAAVVIVGTVLLSLGASFGLSVLLWQYILGLKLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +AVILLLAVGSDYNLLLISRFKEEI AGL TG IRAMAG+G VVT+AGLVFAATM++F+F Sbjct 833 MAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S L V+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 RP VREL+L + + P Sbjct 953 RPAVRELILNDVEEHP 968 Score = 48.9 bits (115), Expect = 0.002, Method: Compositional matrix adjust. Identities = 37/170 (22%), Positives = 74/170 (44%), Gaps = 5/170 (2%) Query 169 GAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSL 228 G Y+ G F D + + +I+L+++ + RS + L+++ V + L Sbjct 177 GIKAYVTGAGPLFADQSHAGEKGVAKVTLVTFLVIILMLLFVYRSAITMLIMLVMVFIEL 236 Query 229 GASFGLSVLVWQH-LLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TG 285 A+ G+ ++ + ++G+ + + V++ +A G+DY + ++ R+ E G G + Sbjct 237 AAARGVVAVLGNYGIIGLSTF--ANNMLVLMAIAAGTDYAIFVVGRYHEARGLGESREKA 294 Query 286 IIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTL 335 T VV +GL A M F L +G +G+L L Sbjct 295 FYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFQTLGVPCAVGMLVAVL 344 >gi|118462678|ref|YP_883823.1| MmpL4 protein [Mycobacterium avium 104] gi|118163965|gb|ABK64862.1| MmpL4 protein [Mycobacterium avium 104] Length=976 Score = 543 bits (1398), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 259/376 (69%), Positives = 313/376 (84%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVF+ +DGIDQ+ E + +++ LDKL IQP+LVAL+P +I SQQ N + ++NYA Sbjct 593 WALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S DG+A R Sbjct 653 ITQGLNDQAKAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPA+PEGI HI+ IKQA HEA+KGTP GA +YL GTAAT+KD+ DG+ DLL Sbjct 713 LIISHEGDPASPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLL 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRS+VAA VIVGTV LSLGASFGLSVL+WQ+LLG++L+W+VLA Sbjct 773 IAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYLLGLKLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +AVILLLAVGSDYNLLLISRFKEEI AGL TG IRAMAG+G VVT+AGLVFAATM++F+F Sbjct 833 MAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S L V+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 R VREL+L + ++ P Sbjct 953 RRAVRELILADVDEHP 968 Score = 43.9 bits (102), Expect = 0.043, Method: Compositional matrix adjust. Identities = 36/166 (22%), Positives = 74/166 (45%), Gaps = 5/166 (3%) Query 169 GAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSL 228 G Y+ G F D + + + +I+++++++ RS++ V++G V + L Sbjct 177 GIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSIITVAVMLGMVFIEL 236 Query 229 GASFGLSVLVWQH-LLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAG--LNTG 285 A+ G+ + + ++G+ + + V++ +A G+DY + ++ R+ E G G Sbjct 237 AAARGVVATLGNYGVMGLSTF--ANNMLVLMAIAAGTDYAIFVVGRYHEARGLGETREQA 294 Query 286 IIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 T VV +GL A M F L +G +G+L Sbjct 295 FYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFQSLGVPCAVGML 340 >gi|41410045|ref|NP_962881.1| MmpL4_7 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398878|gb|AAS06497.1| MmpL4_7 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460311|gb|EGO39211.1| Transport protein [Mycobacterium avium subsp. paratuberculosis S397] Length=976 Score = 542 bits (1396), Expect = 5e-152, Method: Compositional matrix adjust. Identities = 258/376 (69%), Positives = 313/376 (84%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVF+ +DGIDQ+ E + +++ LDKL IQP+LVAL+P +I SQQ N + ++NYA Sbjct 593 WALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S DG+A R Sbjct 653 ITQGLNDQAKAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPA+PEGI HI+ IKQA HEA+KGTP GA +YL GTAAT+KD+ DG+ DLL Sbjct 713 LIISHEGDPASPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLL 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRS+VAA VIVGTV LSLGASFGLSVL+WQ++LG++L+W+VLA Sbjct 773 IAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYILGLKLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +AVILLLAVGSDYNLLLISRFKEEI AGL TG IRAMAG+G VVT+AGLVFAATM++F+F Sbjct 833 MAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S L V+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 R VREL+L + ++ P Sbjct 953 RRAVRELILADVDEHP 968 Score = 43.9 bits (102), Expect = 0.043, Method: Compositional matrix adjust. Identities = 36/166 (22%), Positives = 74/166 (45%), Gaps = 5/166 (3%) Query 169 GAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSL 228 G Y+ G F D + + + +I+++++++ RS++ V++G V + L Sbjct 177 GIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSIITVAVMLGMVFIEL 236 Query 229 GASFGLSVLVWQH-LLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAG--LNTG 285 A+ G+ + + ++G+ + + V++ +A G+DY + ++ R+ E G G Sbjct 237 AAARGVVATLGNYGVMGLSTF--ANNMLVLMAIAAGTDYAIFVVGRYHEARGLGETREQA 294 Query 286 IIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 T VV +GL A M F L +G +G+L Sbjct 295 FYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFQSLGVPCAVGML 340 >gi|254777133|ref|ZP_05218649.1| MmpL4_7 [Mycobacterium avium subsp. avium ATCC 25291] Length=976 Score = 541 bits (1395), Expect = 5e-152, Method: Compositional matrix adjust. Identities = 258/376 (69%), Positives = 313/376 (84%), Gaps = 0/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVF+ +DGIDQ+ E + +++ LDKL IQP+LVAL+P +I SQQ N + ++NYA Sbjct 593 WALRSVFNALDGIDQVAENIVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYA 652 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 G+ Q A +NA A G AFD AKNDD+FYLPPEAF +PDF RGLK F+S DG+A R Sbjct 653 ITQGLNDQAKAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAVR 712 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +IISHEGDPA+PEGI HI+ IKQA HEA+KGTP GA +YL GTAAT+KD+ DG+ DLL Sbjct 713 LIISHEGDPASPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYKDMHDGSNIDLL 772 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA +LI +IM++ITRS+VAA VIVGTV LSLGASFGLSVL+WQ++LG++L+W+VLA Sbjct 773 IAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASFGLSVLLWQYILGLKLHWMVLA 832 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +AVILLLAVGSDYNLLLISRFKEEI AGL TG IRAMAG+G VVT+AGLVFAATM++F+F Sbjct 833 MAVILLLAVGSDYNLLLISRFKEEIHAGLKTGTIRAMAGSGSVVTSAGLVFAATMATFMF 892 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 S L V+ Q+GTTI LGLLFDTL+VR+FMTPS+A LLGRWFWWPQ VRPRPAS MLRPYGP Sbjct 893 SPLLVMAQVGTTIALGLLFDTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGP 952 Query 374 RPVVRELLLREGNDDP 389 R VREL+L + ++ P Sbjct 953 RRAVRELILADVDEHP 968 Score = 43.9 bits (102), Expect = 0.042, Method: Compositional matrix adjust. Identities = 36/166 (22%), Positives = 74/166 (45%), Gaps = 5/166 (3%) Query 169 GAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSL 228 G Y+ G F D + + + +I+++++++ RS++ V++G V + L Sbjct 177 GIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVIIVMLLVVYRSIITVAVMLGMVFIEL 236 Query 229 GASFGLSVLVWQH-LLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAG--LNTG 285 A+ G+ + + ++G+ + + V++ +A G+DY + ++ R+ E G G Sbjct 237 AAARGVVATLGNYGVMGLSTF--ANNMLVLMAIAAGTDYAIFVVGRYHEARGLGETREQA 294 Query 286 IIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 T VV +GL A M F L +G +G+L Sbjct 295 FYTMFHSTAHVVLGSGLTIAGAMYCLSFCRLPYFQSLGVPCAVGML 340 >gi|336460142|gb|EGO39047.1| Transport protein [Mycobacterium avium subsp. paratuberculosis S397] Length=979 Score = 532 bits (1371), Expect = 4e-149, Method: Compositional matrix adjust. Identities = 261/374 (70%), Positives = 319/374 (86%), Gaps = 0/374 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVFDT+DGID L ++L ++ LDKL + PQ++A +P IA+ + + L ++ Sbjct 588 WSLRSVFDTLDGIDLLSDKLTELSRDLDKLDVLMPQMLAQMPPMIATMTTMKTMMLTMHS 647 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 +MS +Y Q + +N+ AMGQAFDA+KNDDSFY+PPE FDNPDF+RGLK+FLS DG AAR Sbjct 648 SMSSLYDQMDVMSQNSTAMGQAFDASKNDDSFYIPPEVFDNPDFKRGLKMFLSPDGHAAR 707 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISHEGDPATPEGISH+D IK AA EA+KGTP+ GA I+LAGTAA +KD++D A YDL+ Sbjct 708 FIISHEGDPATPEGISHVDPIKNAAKEAIKGTPLEGAKIWLAGTAAVYKDMRDEAKYDLM 767 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGI+A SLIL+IM+IITRSLVAA+VIVGTV LSLGASFGLSVLVWQ ++G +L+W+VLA Sbjct 768 IAGISAASLILIIMLIITRSLVAAIVIVGTVLLSLGASFGLSVLVWQDIIGFKLHWMVLA 827 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VIL+LAVGSDYNLLL+SRFKEEI AG+ TGIIR+MAGTG VVT+AGLVFAATM+SFVF Sbjct 828 MSVILMLAVGSDYNLLLVSRFKEEIAAGIKTGIIRSMAGTGAVVTSAGLVFAATMASFVF 887 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDL+V+GQ+GTTIGLGLLFDTL+VR+FM PS+A L+GRWFWWPQ+VR RPAS+MLRPYGP Sbjct 888 SDLKVIGQVGTTIGLGLLFDTLIVRSFMMPSVAALMGRWFWWPQQVRTRPASQMLRPYGP 947 Query 374 RPVVRELLLREGND 387 RP VR LLL E D Sbjct 948 RPAVRTLLLPENRD 961 Score = 63.9 bits (154), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 53/210 (26%), Positives = 100/210 (48%), Gaps = 10/210 (4%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKDI 184 S+DGKAA + + G+ +G S + A + V P G Y+ G AA D Sbjct 132 SSDGKAAYVQVYLAGN----QGESLANESVAAVRKTVGSVPAPPGIKAYVTGPAALLADQ 187 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQHLL 243 + + +I+++++ + RS+V L+ + V + L A+ G+ ++L +++++ Sbjct 188 SSAGERGVQKVTMITFGVIIVMLLWVYRSIVTVLITLMMVGVELTAARGIIALLSYKNII 247 Query 244 GIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAG 301 G+ + + L V+L +A G+DY + ++ R++E G G + GT VV +G Sbjct 248 GLSTF--AVNLLVLLAIAAGTDYAIFILGRYQEARGVGEDREKAYYTMFHGTAHVVLGSG 305 Query 302 LVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 L A M F+ L +G +G+L Sbjct 306 LTIAGAMYCLSFTRLPYFQTLGVPCAVGML 335 >gi|41409849|ref|NP_962685.1| MmpL4_5 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398681|gb|AAS06301.1| MmpL4_5 [Mycobacterium avium subsp. paratuberculosis K-10] Length=979 Score = 532 bits (1370), Expect = 5e-149, Method: Compositional matrix adjust. Identities = 261/374 (70%), Positives = 318/374 (86%), Gaps = 0/374 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RSVFDT+DGID L ++L ++ LDKL + PQ++A +P IA + + L ++ Sbjct 588 WSLRSVFDTLDGIDLLSDKLTELSRDLDKLDVLMPQMLAQMPPMIAPMTTMKTMMLTMHS 647 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 +MS +Y Q + +N+ AMGQAFDA+KNDDSFY+PPE FDNPDF+RGLK+FLS DG AAR Sbjct 648 SMSSLYDQMDVMSQNSTAMGQAFDASKNDDSFYIPPEVFDNPDFKRGLKMFLSPDGHAAR 707 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISHEGDPATPEGISH+D IK AA EA+KGTP+ GA I+LAGTAA +KD++D A YDL+ Sbjct 708 FIISHEGDPATPEGISHVDPIKNAAKEAIKGTPLEGAKIWLAGTAAVYKDMRDEAKYDLM 767 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGI+A SLIL+IM+IITRSLVAA+VIVGTV LSLGASFGLSVLVWQ ++G +L+W+VLA Sbjct 768 IAGISAASLILIIMLIITRSLVAAIVIVGTVLLSLGASFGLSVLVWQDIIGFKLHWMVLA 827 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VIL+LAVGSDYNLLL+SRFKEEI AG+ TGIIR+MAGTG VVT+AGLVFAATM+SFVF Sbjct 828 MSVILMLAVGSDYNLLLVSRFKEEIAAGIKTGIIRSMAGTGAVVTSAGLVFAATMASFVF 887 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDL+V+GQ+GTTIGLGLLFDTL+VR+FM PS+A L+GRWFWWPQ+VR RPAS+MLRPYGP Sbjct 888 SDLKVIGQVGTTIGLGLLFDTLIVRSFMMPSVAALMGRWFWWPQQVRTRPASQMLRPYGP 947 Query 374 RPVVRELLLREGND 387 RP VR LLL E D Sbjct 948 RPAVRTLLLPENRD 961 Score = 63.9 bits (154), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 53/210 (26%), Positives = 100/210 (48%), Gaps = 10/210 (4%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKDI 184 S+DGKAA + + G+ +G S + A + V P G Y+ G AA D Sbjct 132 SSDGKAAYVQVYLAGN----QGESLANESVAAVRKTVGSVPAPPGIKAYVTGPAALLADQ 187 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQHLL 243 + + +I+++++ + RS+V L+ + V + L A+ G+ ++L +++++ Sbjct 188 SSAGERGVQKVTMITFGVIIVMLLWVYRSIVTVLITLMMVGVELTAARGIIALLSYKNII 247 Query 244 GIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAG 301 G+ + + L V+L +A G+DY + ++ R++E G G + GT VV +G Sbjct 248 GLSTF--AVNLLVLLAIAAGTDYAIFILGRYQEARGVGEDREKAYYTMFHGTAHVVLGSG 305 Query 302 LVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 L A M F+ L +G +G+L Sbjct 306 LTIAGAMYCLSFTRLPYFQTLGVPCAVGML 335 >gi|118470823|ref|YP_884795.1| transporter [Mycobacterium smegmatis str. MC2 155] gi|9664815|gb|AAF97217.1|AF271635_1 putative transport membrane protein C [Mycobacterium smegmatis] gi|82393551|gb|ABB72062.1| Mmpl4b [Mycobacterium smegmatis str. MC2 155] gi|118172110|gb|ABK73006.1| putative transport protein [Mycobacterium smegmatis str. MC2 155] Length=994 Score = 529 bits (1363), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 250/368 (68%), Positives = 308/368 (84%), Gaps = 0/368 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG+D+L ++L + +D+L A+ P+LVA P+ IAS + REL L +Y+ Sbjct 598 WSLRSIFDAMDGVDRLNDELQVLVDNMDRLDALVPELVAQFPEYIASMETFRELTLTSYS 657 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T SG+ Q E+ AMGQAFDAAKNDD+F+LPPE FDNPDF+R + FLS DGKAAR Sbjct 658 TFSGLLQQMDEQTEDVTAMGQAFDAAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAAR 717 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDPATPEGIS +D ++ AA EA+KGTP+ A +YLAGTA T KD +DG+TYDLL Sbjct 718 FIISHNGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGSTYDLL 777 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA+ LI +IM+I+TRS +AALVIVGTV LSLGASFGLSVL+WQ++LGI L+W+VLA Sbjct 778 IAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLLWQYILGIHLHWMVLA 837 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEE+GAG+NTGI+RAM GTG VVT+AGLVFA TM++ V Sbjct 838 MSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVRAMGGTGKVVTSAGLVFAGTMAAMVV 897 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDT++VR+FMTPSIA LLGRWFWWPQ+VRPRPAS +L PYGP Sbjct 898 SDLRIIGQIGTTIGLGLLFDTMIVRSFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGP 957 Query 374 RPVVRELL 381 RP+VR LL Sbjct 958 RPLVRALL 965 Score = 66.6 bits (161), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 51/208 (25%), Positives = 97/208 (47%), Gaps = 8/208 (3%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPM-AGAGIYLAGTAATFKDI 184 SADGKAA + ++ G+ TP G + A++ + V TP G +Y+ G A D+ Sbjct 142 SADGKAAYVQLNLAGNQGTPLGDESVAAVR----DLVARTPAPEGVSVYVTGAAPLVSDM 197 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLG 244 Q +L + +I +++++ RS++ ++++ V + A+ G+ + + + Sbjct 198 QHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILLLIMVGFEVAAARGIVAFLGANEVF 257 Query 245 IQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAGL 302 + L + + V L +A G+DY + R++E AG + T G VV A+GL Sbjct 258 V-LSTFAVNMLVFLAIAAGTDYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGL 316 Query 303 VFAATMSSFVFSDLRVLGQIGTTIGLGL 330 A + F+ L +G +G+ Sbjct 317 TIAGAIFCLTFTRLPYFHTMGVPCAIGM 344 >gi|23345076|gb|AAN28686.1| putative membrane protein [Mycobacterium smegmatis] Length=902 Score = 529 bits (1362), Expect = 4e-148, Method: Compositional matrix adjust. Identities = 250/368 (68%), Positives = 308/368 (84%), Gaps = 0/368 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG+D+L ++L + +D+L A+ P+LVA P+ IAS + REL L +Y+ Sbjct 506 WSLRSIFDAMDGVDRLNDELQVLVDNMDRLDALVPELVAQFPEYIASMETFRELTLTSYS 565 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T SG+ Q E+ AMGQAFDAAKNDD+F+LPPE FDNPDF+R + FLS DGKAAR Sbjct 566 TFSGLLQQMDEQTEDVTAMGQAFDAAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAAR 625 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDPATPEGIS +D ++ AA EA+KGTP+ A +YLAGTA T KD +DG+TYDLL Sbjct 626 FIISHNGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGSTYDLL 685 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA+ LI +IM+I+TRS +AALVIVGTV LSLGASFGLSVL+WQ++LGI L+W+VLA Sbjct 686 IAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLLWQYILGIHLHWMVLA 745 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEE+GAG+NTGI+RAM GTG VVT+AGLVFA TM++ V Sbjct 746 MSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVRAMGGTGKVVTSAGLVFAGTMAAMVV 805 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDT++VR+FMTPSIA LLGRWFWWPQ+VRPRPAS +L PYGP Sbjct 806 SDLRIIGQIGTTIGLGLLFDTMIVRSFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGP 865 Query 374 RPVVRELL 381 RP+VR LL Sbjct 866 RPLVRALL 873 Score = 66.6 bits (161), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 60/237 (26%), Positives = 110/237 (47%), Gaps = 10/237 (4%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPM-AGAGIYLAGTAATFKDI 184 SADGKAA + ++ G+ TP G + A++ + V TP G +Y+ G A D+ Sbjct 50 SADGKAAYVQLNLAGNQGTPLGDESVAAVR----DLVARTPAPEGVSVYVTGAAPLVSDM 105 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLG 244 Q +L + +I +++++ RS++ ++++ V + A+ G+ + + + Sbjct 106 QHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILLLIMVGFEVAAARGIVAFLGANEVF 165 Query 245 IQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAGL 302 + L + + V L +A G+DY + R++E AG + T G VV A+GL Sbjct 166 V-LSTFAVNMLVFLAIAAGTDYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGL 224 Query 303 VFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWW-PQR 358 A + F+ L +G +G+L + V + P+ L GR W P+R Sbjct 225 TIAGAIFCLTFTRLPYFHTMGVPCAIGMLA-AVAVAVTLVPAGVALAGRIGWLEPKR 280 >gi|333989520|ref|YP_004522134.1| transporter [Mycobacterium sp. JDM601] gi|333485488|gb|AEF34880.1| transmembrane transport protein MmpL5_2 [Mycobacterium sp. JDM601] Length=956 Score = 528 bits (1361), Expect = 5e-148, Method: Compositional matrix adjust. Identities = 274/342 (81%), Positives = 306/342 (90%), Gaps = 0/342 (0%) Query 16 VRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATM 75 +RSVFD DGID+L E+L +T LD+L A+QPQLV L+P +I SQQ+NR+LAL NYAT Sbjct 586 LRSVFDLQDGIDKLAEKLQQLTSALDQLDALQPQLVELIPSQIESQQVNRDLALNNYATN 645 Query 76 SGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMI 135 SGI Q+AA ++ AAMG+AFD AKNDDSFYLPPEAF NP+F+RG+KLFLS DGKAA++I Sbjct 646 SGISDQSAAANDDPAAMGRAFDDAKNDDSFYLPPEAFTNPEFKRGMKLFLSPDGKAAQLI 705 Query 136 ISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIA 195 I+HEGDPATPEGISHID I+ AA EAVKGTP+ G+ IYLAGTA+T+KDI D A YDLLIA Sbjct 706 ITHEGDPATPEGISHIDKIRDAAKEAVKGTPLQGSHIYLAGTASTYKDIADAAKYDLLIA 765 Query 196 GIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALA 255 GIAALSLILLIMMIITRSLVAA+VIVGTVALSLGASFGLSVLVWQ+L GI LYWIVLALA Sbjct 766 GIAALSLILLIMMIITRSLVAAIVIVGTVALSLGASFGLSVLVWQYLFGIHLYWIVLALA 825 Query 256 VILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSD 315 VILLLAVGSDYNLLLISRFKEEI AGLNTGIIRAM GTG VVTAAGLVFAATM+SF+FSD Sbjct 826 VILLLAVGSDYNLLLISRFKEEIDAGLNTGIIRAMGGTGSVVTAAGLVFAATMASFIFSD 885 Query 316 LRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQ 357 LR+LGQIGTTI LGLLFDTL+VR+FMTPSIA LLGRWFWWPQ Sbjct 886 LRILGQIGTTIALGLLFDTLIVRSFMTPSIAALLGRWFWWPQ 927 Score = 51.2 bits (121), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 53/211 (26%), Positives = 94/211 (45%), Gaps = 12/211 (5%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKD- 183 S DGKAA + G +G + + A + V+G P G Y+ G A D Sbjct 128 SNDGKAALTQVFLAGS----QGETLANQSVAAVRDIVEGVPAPPGVRAYVTGAAPLVADQ 183 Query 184 IQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQHL 242 G+ + I L +I +++ + RS+ ++ + TVA+ + A+ G + L + + Sbjct 184 FSVGSEGTNKVTAITFL-VIAIMLFAVYRSVATTVLALLTVAIEMAAARGFVAFLGYHEV 242 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVTAA 300 +G+ Y L +L +A G+DY + +ISR++E +G T GT VV + Sbjct 243 IGLSTY--STNLLTLLAIAAGTDYAIFIISRYQEARAVGEDPETAFYTMYRGTAHVVIGS 300 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 GL + + F+ L +G +G+ Sbjct 301 GLTISGAVYCLSFTRLPYFHTLGLPAAIGIF 331 >gi|183980799|ref|YP_001849090.1| MmpL family transport protein [Mycobacterium marinum M] gi|183174125|gb|ACC39235.1| conserved transmembrane transport protein - MmpL family [Mycobacterium marinum M] Length=1008 Score = 523 bits (1348), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 253/374 (68%), Positives = 319/374 (86%), Gaps = 0/374 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG+D++ E+LA+++ +D+L + PQ+ A +P +IAS + + + L ++ Sbjct 615 WSLRSIFDALDGVDKITEKLAALSRDMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHS 674 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 +MS +Y Q + +N+ AMG+AFDAA+NDDSFY+PPE FDN DF+RGLK+FLS DG A R Sbjct 675 SMSSLYDQMDEMSKNSTAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVR 734 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISHEGDPA+ EGISH+ I A +A+KGTP+ GA IYLAGTA+ +KD++DG+ +DLL Sbjct 735 FIISHEGDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLL 794 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IM+IITRSLVAA+VIVGTV LSLGASFGLSVLVWQ + G++L+W+VLA Sbjct 795 IAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGVELHWMVLA 854 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLL+SR KEEIGAGL TGIIRAMAGTGGVVT AGLVFAATM+SF+F Sbjct 855 MSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGGVVTTAGLVFAATMASFIF 914 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLRV+GQ+GTTIGLGLLFDTL+VR+FMTPSIA L+GRWFWWPQ+VR RPAS++LRPYGP Sbjct 915 SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGP 974 Query 374 RPVVRELLLREGND 387 RP+VR LLL D Sbjct 975 RPLVRALLLPRNGD 988 Score = 61.6 bits (148), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 52/210 (25%), Positives = 95/210 (46%), Gaps = 10/210 (4%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKDI 184 S DGKAA + G+ + +DA++ E V TP G Y+ G AA D Sbjct 159 SPDGKAAYVQAYLVGNQGEAKANESVDAVR----ELVNDTPAPPGVKAYVTGPAALIADQ 214 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQHLL 243 + + +I ++++ + RSL+ + ++ V + L A+ G+ + L +++ Sbjct 215 STAGDASIQRVTFITIGVIFVMLLSVYRSLITVISVLVMVGIELMAARGVVAFLADNNVI 274 Query 244 GIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAG--LNTGIIRAMAGTGGVVTAAG 301 G+ + + L V++ +A G+DY + ++ R++E G G GT VV +G Sbjct 275 GLSTF--AVNLLVLMAIAAGTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSG 332 Query 302 LVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 L A M F+ L +G +G+L Sbjct 333 LTIAGAMYCLSFTRLPYFQTLGAPCAVGML 362 >gi|183980865|ref|YP_001849156.1| transmembrane transport protein, MmpL2 [Mycobacterium marinum M] gi|183174191|gb|ACC39301.1| conserved transmembrane transport protein, MmpL2 [Mycobacterium marinum M] Length=997 Score = 523 bits (1347), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 256/377 (68%), Positives = 306/377 (82%), Gaps = 0/377 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +R +FD D +DQL E+L + +D L + P++ A +P I + I R++ L + Sbjct 587 WSIRQIFDMFDSVDQLSEKLEYLVKDMDMLITLLPKMRAQIPPMINTMTIMRDMLLVWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q + ++ AMG+ FDAA+ DDSFYLP AF NPDFQRGLK+FLS DGKAAR Sbjct 647 TLQSFYEQQDSGSKDPGAMGRVFDAAQIDDSFYLPESAFKNPDFQRGLKMFLSKDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 II+ +GDPAT GIS + +IKQ A EA+KGTP+ GA IYL GTAATFKDI +GAT+DLL Sbjct 707 FIIALDGDPATSAGISRVASIKQEAREAIKGTPLQGAAIYLGGTAATFKDISEGATFDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLI++IMM+ITRS+VAA VIVGTV LS+G+SFGLSVLVW+ +LGI+LYW+VLA Sbjct 767 IAGVAAISLIVIIMMLITRSVVAAAVIVGTVLLSMGSSFGLSVLVWEDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTL+VR+FMTPSIA LLGRWFWWPQRVRPRPAS+MLRP GP Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPQRVRPRPASQMLRPSGP 946 Query 374 RPVVRELLLREGNDDPR 390 R +VR LLL N P Sbjct 947 RSLVRALLLSPENKSPE 963 Score = 58.9 bits (141), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 57/211 (28%), Positives = 96/211 (46%), Gaps = 13/211 (6%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKDI 184 SAD KAA +++ G T E + + A++ V TP G Y+ G +A D Sbjct 132 SADDKAAYVVVYIVGKNET-EAYASVHAVRHI----VDNTPAPPGLKAYVTGPSALNADQ 186 Query 185 QDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHL 242 + D IA + A++ +I ++++ I RS+V A +++ V + LGA G + H Sbjct 187 AEAG--DKSIAKVTAITSVVIAVMLLFIYRSVVTAFLVLIMVGIDLGAIRGTIAFLANHN 244 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 + L L V+L +A +DY + ++ R+ E AG + T GT V+ + Sbjct 245 I-FNLSTFATNLLVLLAIAASTDYAIFMLGRYHEARYAGEDRETAFYTMFHGTAHVILGS 303 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 GL A M F+ L + +G+L Sbjct 304 GLTIAGAMYCLSFARLPYFQTLAAPCAIGML 334 >gi|169628084|ref|YP_001701733.1| membrane protein MmpL [Mycobacterium abscessus ATCC 19977] gi|169240051|emb|CAM61079.1| Probable membrane protein, MmpL [Mycobacterium abscessus] Length=956 Score = 521 bits (1341), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 254/360 (71%), Positives = 302/360 (84%), Gaps = 3/360 (0%) Query 16 VRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATM 75 +RSVFD +DGID+L + L SVT +L KL A+QP+LV L+P +IA Q+ NR+L L+NYA Sbjct 586 LRSVFDALDGIDELVDALQSVTGSLTKLDALQPKLVDLIPPQIAIQEKNRDLTLSNYAIN 645 Query 76 SGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMI 135 +G Q A +G+AFD AKNDDSFYLPPEAFDNP F+RG+KLF+S DGKAARMI Sbjct 646 NGTNTQNEESTRTATELGKAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMI 705 Query 136 ISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIA 195 I+H+GDP T EGI+HIDAIK+AA +AVK TP+A A IY+AGTA+ +KDI DG YDLL+A Sbjct 706 ITHQGDPQTSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQKYDLLMA 765 Query 196 GIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALA 255 +A+L LILLIMM +TRSLVAALVIVGTVALSL ASFG+SV+VWQ++ GI LYW++ LA Sbjct 766 ALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVVWQYIFGIPLYWVIFPLA 825 Query 256 VILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSD 315 VI+LLAVG+DYNLLLISRFKEE GAGL TGIIRA+AGTGGVVTAAGLVFA TMSSFVFSD Sbjct 826 VIILLAVGADYNLLLISRFKEETGAGLKTGIIRAIAGTGGVVTAAGLVFAVTMSSFVFSD 885 Query 316 LRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRP 375 LRVLGQIGTTIGLGLLFDTLVVR+F+TP+IA +LGRWFWWP +R RPA +P+GP+P Sbjct 886 LRVLGQIGTTIGLGLLFDTLVVRSFLTPAIATMLGRWFWWPINIRTRPAP---KPFGPKP 942 Score = 54.3 bits (129), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/207 (25%), Positives = 90/207 (44%), Gaps = 8/207 (3%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMA-GAGIYLAGTAATFKDI 184 S DGKAA + + G+ +DA+++ E TP G Y++G A T D Sbjct 128 SKDGKAAYVQVYVAGNQGEALSNESVDAVRRIIAE----TPAPDGIKAYVSGEAPTITDQ 183 Query 185 QDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLG 244 + I ++I ++++++ RSL+ +++ V + L A+ G+ V H Sbjct 184 FEVGNAGAAQVTIITFAVIAVMLLVVYRSLITTALVLAMVMVELSAARGI-VAALGHTGV 242 Query 245 IQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAGL 302 I L L +L +A G+DY + + R++E AG + + T V+ +GL Sbjct 243 IGLSTYATNLLTMLAIAAGTDYAIFFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGL 302 Query 303 VFAATMSSFVFSDLRVLGQIGTTIGLG 329 A + F+ L +G LG Sbjct 303 TVAGALFCLSFTRLPYFQTLGVPAALG 329 >gi|240171915|ref|ZP_04750574.1| transmembrane transport protein, MmpL2 [Mycobacterium kansasii ATCC 12478] Length=1015 Score = 520 bits (1338), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 254/369 (69%), Positives = 304/369 (83%), Gaps = 0/369 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD ID +DQ+ E+L + +D L + PQ+ A +P I + I R++ + + Sbjct 587 WSIRSIFDMIDNVDQMSEKLEYLVTDMDILVKLLPQMRAQIPPMINTMTIMRDMLVVWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q+ ++ AMG+ FDAA+ DDSFYLP AF NPDFQRGLK+FLS DGKAAR Sbjct 647 TLQSFYDQSDTGSKDPGAMGRVFDAAQIDDSFYLPQSAFKNPDFQRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 II+ EGDPAT GI+ ++ IK A EA+KGTP+ GA IYL GTAATF DIQ+ ATYDLL Sbjct 707 FIIALEGDPATSAGIARVEQIKDEAREAIKGTPLQGAAIYLGGTAATFHDIQEAATYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLI++IMM+ITRS+VAA VIVGTV +S+G+SFGLSVLVW+ +LGI+LYW+VLA Sbjct 767 IAGVAAISLIVIIMMLITRSVVAAAVIVGTVLVSMGSSFGLSVLVWEDILGIELYWLVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTL+VR+FMTPSIA LLGRWFWWPQRVRPRPASRMLR YGP Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPQRVRPRPASRMLRAYGP 946 Query 374 RPVVRELLL 382 R +VR LLL Sbjct 947 RRLVRALLL 955 Score = 65.1 bits (157), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 67/234 (29%), Positives = 115/234 (50%), Gaps = 17/234 (7%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 SAD KAA +++ GD T E + + A++ H +P G Y+ G +A D Sbjct 132 SADDKAAYVVVYLVGDNET-EAYASVHAVR---HIVDTTSPPRGVKAYVTGPSALNADQA 187 Query 186 DGATYDLLIAGIAAL-SLILLIMMI-ITRSLVAALVIVGTVALSLGASFG-LSVLVWQHL 242 + D IA + A+ SL++ +M++ I RS+V A +++ V + LGA G ++ L +++ Sbjct 188 EAG--DKSIAKVTAITSLVIAVMLLFIYRSVVTAFLVLIMVGIDLGAIRGTIAFLADRNV 245 Query 243 LGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAA 300 + + L V+L +A +DY + ++ R+ E AG + T GT V+ + Sbjct 246 FSLSTF--ATNLLVLLAIAATTDYAIFMLGRYHEARNAGEDRETAFYTMFHGTAHVILGS 303 Query 301 GLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVL-LGRWF 353 GL A M F+ L +G +G+L + V A +T AVL +G +F Sbjct 304 GLTIAGAMYCLSFARLPYFNTLGPPCAIGML---VAVFAALTLGPAVLAIGSFF 354 >gi|296164371|ref|ZP_06846948.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900274|gb|EFG79703.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=977 Score = 515 bits (1326), Expect = 6e-144, Method: Compositional matrix adjust. Identities = 254/378 (68%), Positives = 319/378 (85%), Gaps = 1/378 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG+DQ+ E+ + + +L A+ PQ++A +P IA+ +++ L ++ Sbjct 588 WSLRSLFDALDGLDQITEKFTYLAGDISQLDALMPQMLAQMPPMIATMTTMKQMMLTMHS 647 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 +MS +Y Q + +N+ AMGQAFDAAKNDDSFY+PPE FDNPDF+RGLK+FLS DG AAR Sbjct 648 SMSSLYDQMDVMSQNSTAMGQAFDAAKNDDSFYIPPEVFDNPDFKRGLKMFLSPDGHAAR 707 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISHEGDPATPEGISH++ IK AA EA+KGTP+ GA IYLAGTAA +KD++DG+ YDL+ Sbjct 708 FIISHEGDPATPEGISHVEPIKNAAKEAIKGTPLEGAKIYLAGTAAVYKDMRDGSKYDLM 767 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IA IAA SLIL+IM+IITRSLVAA+ IVGTV +SLGASFGLSVLVWQ ++G +L+W+VLA Sbjct 768 IAAIAAASLILIIMLIITRSLVAAVTIVGTVLISLGASFGLSVLVWQDIIGFKLHWMVLA 827 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 +++IL+LAVGSDYNLLL+SRFKEEIGAGL TGIIR+MAGTG VVT+AGLVFAATM+SF+F Sbjct 828 MSIILMLAVGSDYNLLLVSRFKEEIGAGLKTGIIRSMAGTGAVVTSAGLVFAATMASFIF 887 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDL+V+GQ+GTTIGLGLLFDTL+VR+FM PS+A LLGRWFWWPQ+VR RPAS++LRPYGP Sbjct 888 SDLKVVGQVGTTIGLGLLFDTLIVRSFMMPSVAALLGRWFWWPQQVRTRPASQLLRPYGP 947 Query 374 RPVVRELLLREGNDDPRT 391 R VR LL DDP++ Sbjct 948 RSAVRAYLLPR-QDDPQS 964 Score = 58.5 bits (140), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 57/236 (25%), Positives = 109/236 (47%), Gaps = 20/236 (8%) Query 126 SADGKAARM---IISHEGDPATPEGISHIDAIKQAAHEAVKGTPM-AGAGIYLAGTAATF 181 S+DGKAA + + ++G+ E ++ A + V P +G Y+ G A Sbjct 132 SSDGKAAYVQAYLAGNQGESLASESVA-------AVRKIVDSVPAPSGVKAYVTGAGALI 184 Query 182 KDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQ 240 D L I +I+++++ + RS++ + V + + A+ G+ + L + Sbjct 185 ADQHSAGQKSLQKVTIITFVVIIVMLLWVYRSIITVFSTLFMVVIEVMAARGVVAFLAYN 244 Query 241 HLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVT 298 +++G+ + + + V+L +A G+DY + ++ R++E G G + GT VV Sbjct 245 NIMGLSTF--AVNILVLLAIAAGTDYAIFILGRYQEARGLGEDREKAFYTMFHGTAHVVL 302 Query 299 AAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVL-LGRWF 353 +GL A M F+ L +G +G+L + V A +T AVL +G +F Sbjct 303 GSGLTIAGAMYCLSFTRLPYFQTMGIPCAVGML---VAVAAALTLGPAVLTVGSFF 355 >gi|15839900|ref|NP_334937.1| MmpL family membrane protein [Mycobacterium tuberculosis CDC1551] gi|254230854|ref|ZP_04924181.1| transmembrane transport protein mmpL2 [Mycobacterium tuberculosis C] gi|13880037|gb|AAK44751.1| membrane protein, MmpL family [Mycobacterium tuberculosis CDC1551] gi|124599913|gb|EAY58923.1| transmembrane transport protein mmpL2 [Mycobacterium tuberculosis C] gi|323721184|gb|EGB30246.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis CDC1551A] Length=968 Score = 510 bits (1314), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 260/373 (70%), Positives = 309/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q A ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQARNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGIS ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.2 bits (160), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|289749002|ref|ZP_06508380.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis T92] gi|289689589|gb|EFD57018.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis T92] Length=797 Score = 509 bits (1311), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 259/373 (70%), Positives = 308/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 416 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 475 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 476 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 535 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGIS ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 536 FVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 595 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 596 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 655 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 656 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 715 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 716 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 775 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 776 RRLVRALLLPSGQ 788 Score = 55.1 bits (131), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 45/163 (28%), Positives = 79/163 (49%), Gaps = 7/163 (4%) Query 173 YLAGTAATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGA 230 Y+ G AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA Sbjct 4 YVTGPAALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGA 61 Query 231 SFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIR 288 G L+ H + L L V++ +A +DY + ++ R+ E AG + T Sbjct 62 IRGFIALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYT 120 Query 289 AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 GT V+ +GL A M F+ L +G I +G+L Sbjct 121 MFHGTAHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 163 >gi|15607648|ref|NP_215021.1| transmembrane transport protein MmpL2 [Mycobacterium tuberculosis H37Rv] gi|148660276|ref|YP_001281799.1| transmembrane transport protein MmpL2 [Mycobacterium tuberculosis H37Ra] gi|167970667|ref|ZP_02552944.1| transmembrane transport protein MmpL2 [Mycobacterium tuberculosis H37Ra] 11 more sequence titles Length=968 Score = 509 bits (1311), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 259/373 (70%), Positives = 308/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGIS ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.6 bits (161), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|340625535|ref|YP_004743987.1| putative transmembrane transport protein MMPL2 [Mycobacterium canettii CIPT 140010059] gi|340003725|emb|CCC42850.1| putative conserved transmembrane transport protein MMPL2 [Mycobacterium canettii CIPT 140010059] Length=968 Score = 509 bits (1311), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 259/373 (70%), Positives = 308/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGIS ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 65.9 bits (159), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLLIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|148821709|ref|YP_001286463.1| transmembrane transport protein mmpL2 [Mycobacterium tuberculosis F11] gi|253797439|ref|YP_003030440.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis KZN 1435] gi|254363469|ref|ZP_04979515.1| transmembrane transport protein mmpL2 [Mycobacterium tuberculosis str. Haarlem] 45 more sequence titles Length=968 Score = 509 bits (1310), Expect = 4e-142, Method: Compositional matrix adjust. Identities = 259/373 (70%), Positives = 308/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGIS ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.6 bits (161), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|31791689|ref|NP_854182.1| transmembrane transport protein MmpL2 [Mycobacterium bovis AF2122/97] gi|31617275|emb|CAD93382.1| PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL2 [Mycobacterium bovis AF2122/97] Length=968 Score = 508 bits (1307), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 258/373 (70%), Positives = 307/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGI ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGICRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.2 bits (160), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQH 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|121636425|ref|YP_976648.1| putative transmembrane transport protein mmpL2 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988897|ref|YP_002643584.1| putative transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|289573097|ref|ZP_06453324.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis K85] gi|121492072|emb|CAL70535.1| Probable conserved transmembrane transport protein mmpL2 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772010|dbj|BAH24816.1| putative transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|289537528|gb|EFD42106.1| transmembrane transporter mmpL2 [Mycobacterium tuberculosis K85] gi|341600441|emb|CCC63111.1| probable conserved transmembrane transport protein mmpL2 [Mycobacterium bovis BCG str. Moreau RDJ] Length=968 Score = 507 bits (1306), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 258/373 (70%), Positives = 307/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGI ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGICRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.2 bits (160), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/278 (26%), Positives = 113/278 (41%), Gaps = 32/278 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLL 331 V+ +GL A M F+ L +G I +G+L Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML 334 >gi|339630580|ref|YP_004722222.1| transporter [Mycobacterium africanum GM041182] gi|339329936|emb|CCC25586.1| putative conserved transmembrane transport protein MMPL2 [Mycobacterium africanum GM041182] Length=968 Score = 507 bits (1306), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 258/373 (70%), Positives = 307/373 (83%), Gaps = 0/373 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD D +DQL E+L + +D L + PQ+ A +P I++ R++ L + Sbjct 587 WSIRSIFDMFDSVDQLSEKLEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHG 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 T+ Y Q ++ AMG+ FDAA+ DDSFYLP AF+NPDF+RGLK+FLS DGKAAR Sbjct 647 TLGAFYKQQERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 +I+ EGDPATPEGI ++ IK+ A EA+KGTP+ GA IYL GTAATFKDI++GA YDLL Sbjct 707 FVIALEGDPATPEGICRVEPIKREAREAIKGTPLQGAAIYLGGTAATFKDIREGARYDLL 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AA+SLIL+IMMIITRS+VAA+VIVGTV LS+GASFGLSVLVWQ +LGI+LYW+VLA Sbjct 767 IAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASFGLSVLVWQDILGIELYWMVLA 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VILLLAVGSDYNLLLISR KEEIGAGLNTGIIRAMAGTGGVVTAAG+VFA TMS FVF Sbjct 827 MSVILLLAVGSDYNLLLISRLKEEIGAGLNTGIIRAMAGTGGVVTAAGMVFAVTMSLFVF 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQIGTTIGLGLLFDTLVVR+FMTPSIA LLGRWFWWP RVRPRPAS+MLRP+ P Sbjct 887 SDLRIIGQIGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAP 946 Query 374 RPVVRELLLREGN 386 R +VR LLL G Sbjct 947 RRLVRALLLPSGQ 959 Score = 66.2 bits (160), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 78/301 (26%), Positives = 125/301 (42%), Gaps = 36/301 (11%) Query 83 AALIENAAAMGQAFDAAKNDDSFYL-----PPEAFDNPDFQRGLKLFLSADGKAARMIIS 137 AA I+ +GQ F +D++ + P D F L LSAD + I Sbjct 60 AASIQAIKRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAHIQD 119 Query 138 HEGDPATPEG--------------------ISHIDAIKQAAHEAVKGTPMAGAGIYLAGT 177 GDP T G D++ H P G Y+ G Sbjct 120 FWGDPLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHAVRHMVDTTPPPHGVKAYVTGP 179 Query 178 AATFKDIQDGATYDLLIAGIAALS--LILLIMMIITRSLVAALVIVGTVALSLGASFGLS 235 AA D + D IA + A++ +I ++++I RS++ A++++ V + LGA G Sbjct 180 AALNADQAEAG--DKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFI 237 Query 236 VLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGT 293 L+ H + L L V++ +A +DY + ++ R+ E AG + T GT Sbjct 238 ALLADHNI-FSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGT 296 Query 294 GGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLL-GRW 352 V+ +GL A M F+ L +G I +G+L + V A +T AVL+ G + Sbjct 297 AHVILGSGLTIAGAMYCLSFARLPYFETLGAPIAIGML---VAVLAALTLGPAVLIVGSF 353 Query 353 F 353 F Sbjct 354 F 354 >gi|118471014|ref|YP_884794.1| Mmp14a protein [Mycobacterium smegmatis str. MC2 155] gi|23345075|gb|AAN28685.1| putative membrane protein [Mycobacterium smegmatis] gi|82393550|gb|ABB72061.1| Mmpl4a [Mycobacterium smegmatis str. MC2 155] gi|118172301|gb|ABK73197.1| Mmp14a protein [Mycobacterium smegmatis str. MC2 155] Length=960 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 246/371 (67%), Positives = 305/371 (83%), Gaps = 0/371 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DGI+++ +++ + LD L + PQ++ P IA + +R + L ++ Sbjct 590 WSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLENSRSMILTMHS 649 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TMSGI++Q +NA AMG+AFDAA+NDDSFYLPP+ +N DF+R +K+F+S DGKAAR Sbjct 650 TMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILENEDFKRVMKIFMSPDGKAAR 709 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 M+I+ GDPATPEGI+ ++ I+ AA EA+KGTP+ A ++LAGTAA KD+ DG+ DLL Sbjct 710 MLITQRGDPATPEGIALVEPIRVAAEEALKGTPLESAELHLAGTAAGVKDLVDGSKIDLL 769 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+AAL LI +IM+I+TRS +AALVIVGTVA+SLGASFGLSVLVWQHLLGIQ+ W+VLA Sbjct 770 IAGVAALCLIFIIMLIMTRSFIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLA 829 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEEIGAGLNTGIIRAM GTG VVTAAGLVFAATM+S + Sbjct 830 MSVIVLLAVGSDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV 889 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDL +GQ+GTTIGLGLLFDTLVVRAFMTPSIA LLGRWFWWPQRVR RPAS MLR GP Sbjct 890 SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRPASAMLRSVGP 949 Query 374 RPVVRELLLRE 384 RP+VR LLLR+ Sbjct 950 RPLVRSLLLRD 960 >gi|296164398|ref|ZP_06846973.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900238|gb|EFG79669.1| MmpL family membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=970 Score = 504 bits (1299), Expect = 7e-141, Method: Compositional matrix adjust. Identities = 241/376 (65%), Positives = 303/376 (81%), Gaps = 1/376 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +R++F+T+DG+D L ++L + V LDK+ A+ PQL+ + P IA + R++ L +Y+ Sbjct 584 WSLRNIFETLDGVDTLSDKLDELIVDLDKMDALLPQLLEIFPPSIAIAEEARDMLLTSYS 643 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TM+G Q ENA AMG FDAA++DDSFYLPP+ F N DF++ + FLS DGKAAR Sbjct 644 TMNGTLGQMENQKENATAMGATFDAARDDDSFYLPPDIFQNEDFKKAMSQFLSPDGKAAR 703 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH+GDPA+P G++ ID I+ AA EA+K TP+ + IY+AGTA+TFKD +DG+TYDL Sbjct 704 FIISHKGDPASPAGLARIDKIRTAAEEALKTTPLESSKIYIAGTASTFKDFRDGSTYDLF 763 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+ AL LI +IM+IITR VA+LVIVGTVALSLG+SFGLSVL+WQ++LGI LYW+VL Sbjct 764 IAGVGALCLIFIIMLIITRGFVASLVIVGTVALSLGSSFGLSVLIWQYILGINLYWMVLP 823 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR +EE+ G+NTGI+RAM GTG VVT AGLVFA TM++ V Sbjct 824 MSVIVLLAVGSDYNLLLVSRMREELAGGINTGIVRAMGGTGKVVTNAGLVFAFTMAAMVA 883 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQ+GTTIGLGLLFDTL+VR+FMTPSIA LLGRWFWWPQ VRPRPAS+MLR GP Sbjct 884 SDLRIIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPQIVRPRPASQMLRSEGP 943 Query 374 RPVVRELLL-REGNDD 388 RPVVR LLL RE DD Sbjct 944 RPVVRSLLLHRELEDD 959 Score = 66.2 bits (160), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 53/236 (23%), Positives = 104/236 (45%), Gaps = 6/236 (2%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S DGKA + ++ G+ T G I +++ + P G +Y+ G +A D+Q Sbjct 128 SDDGKAVYVQLNLAGNQGTTLGQDSIASVRDII---ARNPPPPGLKVYVTGPSALLSDMQ 184 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 +L +I ++++ + RS++ ++++ TV + + A+ G+ + H L + Sbjct 185 QAGDRSILKMTAVGALIIFVVLLFVYRSILTVILLLVTVGIEVLAARGIVAFLGDHSL-V 243 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVTAAGLV 303 L + L V L +A G+DY + R++E + G T VV +GL Sbjct 244 ALSTFAVNLLVALAMAAGTDYAIFFFGRYQEARQAGEDRETAFYTTYRAVAPVVLGSGLT 303 Query 304 FAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRV 359 A M F+ + + +G +G+L L+ + + + G + P+RV Sbjct 304 IAGAMLCLGFTRMPIFQTMGMPCAVGMLAAVLIALTLVPAVLTIGSGFGLFDPKRV 359 >gi|254819605|ref|ZP_05224606.1| MmpL4_2 [Mycobacterium intracellulare ATCC 13950] Length=971 Score = 500 bits (1288), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 242/374 (65%), Positives = 299/374 (80%), Gaps = 1/374 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FDT+DGID L ++L + LD + + PQL+ P IA + R++ L N++ Sbjct 584 WSLRSIFDTLDGIDTLSDKLTDLLKDLDNMDKLMPQLLEQYPPMIAMSEDMRQMMLTNHS 643 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TMSGI Q + ++A AMG+AFDA+KNDDSFYLPP+ F+N DF++ + FLS DGKAAR Sbjct 644 TMSGIIGQMDSNNKDAVAMGEAFDASKNDDSFYLPPDIFENADFKKAMSQFLSPDGKAAR 703 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDPAT E ++ ID I+QAA EA+K TP+ A I +AGTA+TFKD +DG+TYDLL Sbjct 704 FIISHRGDPATSESVARIDKIRQAAEEALKNTPLENAKINIAGTASTFKDFRDGSTYDLL 763 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+ AL LI +IM+IITRS +AALVIVGTV LSLGASFGLSVL+WQ++ GI+LYW+VL Sbjct 764 IAGVGALCLIFIIMLIITRSFIAALVIVGTVTLSLGASFGLSVLIWQYIFGIELYWMVLP 823 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEEI AG+NTGIIRAM GTG VVT AGLVFA TM+S V Sbjct 824 MSVIVLLAVGSDYNLLLVSRMKEEIAAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVV 883 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQ+GTTIGLGL+FDTL+VR+FMTP+IA LLGRWFWWP VRPRPAS +LR G Sbjct 884 SDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPLLVRPRPASLLLRSVGT 943 Query 374 RPVVRELLLREGND 387 RP VR LLRE +D Sbjct 944 RPSVRT-LLREDDD 956 Score = 72.8 bits (177), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/242 (25%), Positives = 105/242 (44%), Gaps = 19/242 (7%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S DGKA + ++ G+ T +G + AI+ + P G Y+ G AA F D+Q Sbjct 128 SPDGKAVYVQLNLAGNQGTTQGQESVAAIRDII---ARTPPPPGIQAYVTGPAALFSDMQ 184 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 +L + +I ++++ + RS++ ++++ TV + + A+ G+ + H I Sbjct 185 LAGDRSILKMTMIGALIIFIVLLFVYRSVITVILLLLTVGIEVFAARGVIAFIADHNF-I 243 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVTAAGLV 303 L + L V L +A G+DY + R++E + G T VV +GL Sbjct 244 ALSTFAVNLLVALAMAAGTDYAIFFFGRYQEARQAGEDRETAFFTTYRSVSPVVLGSGLT 303 Query 304 FAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLV----VRAFMT---------PSIAVLLG 350 A M F+ + + +G LG+L L+ V A +T P + G Sbjct 304 IAGAMLCLSFTRMPIFQTMGLPCSLGMLISVLIALTLVPAVLTVGGGVGLFDPKRTIGFG 363 Query 351 RW 352 RW Sbjct 364 RW 365 >gi|118467934|ref|YP_887800.1| MmpL4 protein [Mycobacterium smegmatis str. MC2 155] gi|118169221|gb|ABK70117.1| MmpL4 protein [Mycobacterium smegmatis str. MC2 155] Length=969 Score = 498 bits (1283), Expect = 6e-139, Method: Compositional matrix adjust. Identities = 236/364 (65%), Positives = 297/364 (82%), Gaps = 4/364 (1%) Query 16 VRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATM 75 +RS+FDT+DGID + + + + +D+L + PQ++ ++P I S + + + L ATM Sbjct 602 IRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATM 661 Query 76 SGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMI 135 G+ Q A +EN AMGQAFDA+KNDDSFYLPPE F+NPDF+RG+K+FLS DG A R I Sbjct 662 GGLQDQMEAAMENQTAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFI 721 Query 136 ISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIA 195 ISHEGDP +PEGI HIDAIKQAA EA+KGTP+ G+ IYL GTAATFKD+Q+GA YDL+IA Sbjct 722 ISHEGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIA 781 Query 196 GIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALA 255 GIAAL LI +IM+IITR++VA+ VIVGTV +SLGASFGLSVL+WQH++G++L+W+VLA+A Sbjct 782 GIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAMA 841 Query 256 VILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSD 315 VI+LLAVG+DYNLLL+SR KEEI AGLNTGIIR+M GTG VVT+AGLVFA TM S S+ Sbjct 842 VIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFTMMSMAVSE 901 Query 316 LRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRP 375 L V+ Q+GTTIGLGLLFDTLV+R+FMTPSIA L+G+WFWWPQRVR RP + P+ P+P Sbjct 902 LAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFWWPQRVRQRP---LPAPW-PQP 957 Query 376 VVRE 379 V R+ Sbjct 958 VQRD 961 Score = 54.7 bits (130), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/245 (23%), Positives = 110/245 (45%), Gaps = 16/245 (6%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S DG A+ + + G+ ++A++ E+V P G Y+ G AA D Sbjct 143 SPDGLASYVQVYTRGNQGEALANESVEAVQDIV-ESVPAPP--GVKAYVTGPAALSADQH 199 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGL-SVLVWQHLLG 244 + + + ++I+ +++++ RS+V ++ + V LSL A+ G+ + L + ++G Sbjct 200 VASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIG 259 Query 245 IQLYWIVLALAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVTAAGL 302 + ++ L L +A +DY + LI R++E +G T VV +G+ Sbjct 260 LSVF--ATNLLTTLAIAAATDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGM 317 Query 303 VFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTP-----SIAVLLGRWFWWPQ 357 A F+ + +G + +G+ ++VV A +T S+A G+ F + Sbjct 318 TIAGATLCLHFTRMPYFQSLGIPLAIGM---SVVVLASLTMGAAIISVASRFGKTFEPKR 374 Query 358 RVRPR 362 +R R Sbjct 375 AMRTR 379 >gi|169631193|ref|YP_001704842.1| putative membrane protein MmpL [Mycobacterium abscessus ATCC 19977] gi|146760156|emb|CAJ77701.1| Mmpl4b protein [Mycobacterium abscessus] gi|169243160|emb|CAM64188.1| Putative membrane protein, MmpL [Mycobacterium abscessus] Length=987 Score = 496 bits (1277), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 237/359 (67%), Positives = 287/359 (80%), Gaps = 0/359 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +RS+FD +DG D L + L + +DKL AI PQL+ P I Q R L YA Sbjct 602 WSIRSIFDALDGADALDDGLVELVKNMDKLDAIMPQLLVQFPQMIEVMQSMRTSVLTMYA 661 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TMSG +AQ ++ AMG+AFDA+KNDDSF+LPPE F NPDFQR + FLS DGK R Sbjct 662 TMSGQFAQMDETTDDVMAMGEAFDASKNDDSFFLPPEVFKNPDFQRAMSSFLSPDGKTVR 721 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDP +PEGI+ I+ ++ AA EA+KGTP+ G +Y+AG A+T KD +DG+TYDLL Sbjct 722 FIISHNGDPMSPEGIARIEQVRNAAEEALKGTPLVGGKVYIAGAASTAKDWKDGSTYDLL 781 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGIAA+ L+ +IM+I TRS +AALVIVGTVALSLGASFGLSVL+WQ++LG+ L+W+VLA Sbjct 782 IAGIAAICLVFIIMLITTRSFIAALVIVGTVALSLGASFGLSVLLWQYILGVNLHWMVLA 841 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEE+GAGLNTGIIRAM GTG VVT+AGLVFAATM+S V Sbjct 842 MSVIILLAVGSDYNLLLVSRMKEELGAGLNTGIIRAMGGTGKVVTSAGLVFAATMASMVV 901 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYG 372 SDL+++GQIGTTIGLGLLFDTL+VR+FMTPSIA LLGRWFWWPQRVRPRP S +L P G Sbjct 902 SDLQIIGQIGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPQRVRPRPPSALLTPVG 960 Score = 59.3 bits (142), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 47/207 (23%), Positives = 91/207 (44%), Gaps = 4/207 (1%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S D KAA + ++ G+ T +G + A++ P Y+AG A D+Q Sbjct 144 SPDEKAAYVQLNLVGNQGTAQGDQSVAAVRDIVKRTSPSAP-KDVETYVAGAAPLASDMQ 202 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 +L + +I +++I+ RS++ ++++ V + L A+ G+ + H + + Sbjct 203 HAGNKSILKITAVTVVIIFTLLLILYRSVITVILLLIMVGVELAAARGIVAFLGHHDVFV 262 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLN--TGIIRAMAGTGGVVTAAGLV 303 L + + V L +A G+DY + R++E AG + T VV A+G+ Sbjct 263 -LSTFAVNMLVFLSIAAGTDYGIFFFGRYQEARQAGQDRETAYYTTYRSVAPVVLASGVT 321 Query 304 FAATMSSFVFSDLRVLGQIGTTIGLGL 330 A + F+ L +G +G+ Sbjct 322 IAGAILCLHFTRLPYFQTMGIPCAIGM 348 >gi|146760119|emb|CAJ77681.1| Mmpl4b protein [Mycobacterium chelonae] Length=977 Score = 493 bits (1268), Expect = 3e-137, Method: Compositional matrix adjust. Identities = 242/378 (65%), Positives = 295/378 (79%), Gaps = 1/378 (0%) Query 16 VRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATM 75 +RS+FD +D +D L + L + +D+L AI PQL+ P I+ Q R L YATM Sbjct 596 LRSIFDALDAVDALDDGLMVLVRDMDQLDAIMPQLLVQFPQMISVMQSMRTSVLTMYATM 655 Query 76 SGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMI 135 SG +A + AMGQAFDA+KNDDSF+LPPE F NPDFQR + FLS DGK R I Sbjct 656 SGQFASMDESTNDVMAMGQAFDASKNDDSFFLPPEVFKNPDFQRAMSSFLSPDGKTVRFI 715 Query 136 ISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIA 195 ISH GDP +PEGI+ I+ I+ AA EA+KGTP+ G IYLAG A+T KD +DG+TYDLLIA Sbjct 716 ISHNGDPMSPEGITRIEQIRNAAEEALKGTPLVGGKIYLAGAASTAKDWKDGSTYDLLIA 775 Query 196 GIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALA 255 GIAA+ L+ +IM+I TRS +AALVIVGTVALSLGASFG+SVL+WQ++LGI L+W+VLA++ Sbjct 776 GIAAICLVFIIMLITTRSFIAALVIVGTVALSLGASFGMSVLLWQYILGINLHWMVLAMS 835 Query 256 VILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSD 315 VI+LLAVGSDYNLLL+SR KEE+GAGLNTGIIRAM GTG VVT+AGLVFAATM+S V SD Sbjct 836 VIILLAVGSDYNLLLVSRMKEELGAGLNTGIIRAMGGTGKVVTSAGLVFAATMASMVVSD 895 Query 316 LRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRP 375 L+++GQIGTTIGLGLLFDTL+VR+FMTP+IA LLGRWFWWPQRVRPRP S +L P G RP Sbjct 896 LQIIGQIGTTIGLGLLFDTLIVRSFMTPAIAALLGRWFWWPQRVRPRPPSALLAPVGARP 955 Query 376 VVRELLLREGNDDPRTQV 393 R +D+P T++ Sbjct 956 AA-PAPGRLDDDEPTTEL 972 Score = 64.7 bits (156), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 54/224 (25%), Positives = 99/224 (45%), Gaps = 4/224 (1%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S D KAA + ++ G+ T G + AI++ + + P +Y+AG A D+Q Sbjct 136 SPDEKAAYVQLNLVGNQGTAMGDESVAAIREIVNRTLPSAP-TDVKVYVAGAAPLASDMQ 194 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 +L + +I +++I+ RS+V ++++ V + L A+ G+ + H + + Sbjct 195 HAGNKSILKITAVTVVIIFTLLLILYRSVVTVILLLIMVGVELAAARGIVAFLGYHDVFV 254 Query 246 QLYWIVLALAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVTAAGLV 303 L + + V L +A G+DY + R++E + G T VV A+GL Sbjct 255 -LSTFAVNMLVFLSIAAGTDYGIFFFGRYQEARQAGEDRETAYYTTYRSVAPVVLASGLT 313 Query 304 FAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV 347 A + F+ L +G +G+L V + IAV Sbjct 314 IAGAILCLHFTRLPYFQTMGIPCAIGMLTAVAVAVTLVPAGIAV 357 >gi|342858821|ref|ZP_08715476.1| Mmp14A protein [Mycobacterium colombiense CECT 3035] gi|342134525|gb|EGT87705.1| Mmp14A protein [Mycobacterium colombiense CECT 3035] Length=953 Score = 491 bits (1263), Expect = 1e-136, Method: Compositional matrix adjust. Identities = 231/374 (62%), Positives = 294/374 (79%), Gaps = 0/374 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +R +F+ +DG+D L +++ ++ LD + + PQL+ P IA + R + L N++ Sbjct 565 WSLRQIFEILDGVDTLSDKMVTLLQDLDHMDKLMPQLLEQYPPMIAMSEDMRNMMLTNHS 624 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TMSGI Q ++ ++A MGQAFD +KNDDSFYLPPE F+NPDF++ + FLS DGKAAR Sbjct 625 TMSGIIGQMSSNNKDATIMGQAFDDSKNDDSFYLPPEIFENPDFKKAMTQFLSPDGKAAR 684 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDPAT E ++ ID I+QAA E++K TP+ + IY+AGTA+TFKD +DG+TYDL Sbjct 685 FIISHRGDPATSESVNRIDKIRQAAEESLKNTPLENSKIYIAGTASTFKDFRDGSTYDLF 744 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAGI AL LI +IM+I+TRS +AALVIVGTV LSLGASFG+SVL+WQ++ GI+LYW+VL Sbjct 745 IAGIGALCLIFIIMLILTRSFIAALVIVGTVTLSLGASFGISVLIWQYIFGIKLYWMVLP 804 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEE+ G+NTGIIRAM GTG VVT AGLVFA TM+S V Sbjct 805 MSVIVLLAVGSDYNLLLVSRMKEELAGGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVV 864 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQ+GTTIGLGL+FDTL+VR+FMTP+IA LLGRWFWWPQ VRPRPAS +LR G Sbjct 865 SDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLVRPRPASLLLRSVGT 924 Query 374 RPVVRELLLREGND 387 R VR LL + D Sbjct 925 RQSVRTLLHHDEVD 938 Score = 64.3 bits (155), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 56/247 (23%), Positives = 107/247 (44%), Gaps = 29/247 (11%) Query 126 SADGKAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQ 185 S DGKA + ++ G+ T G + +++ + P G Y+ G +A F D+Q Sbjct 109 SPDGKAVYVQLNLAGNQGTTLGQESVASVRDVI---ARTPPPPGVKAYVTGPSALFSDMQ 165 Query 186 DGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI 245 +L + +I ++++++ RS+ ++++ TV + + A+ G+ + + Sbjct 166 LAGDRSILKMTMIGALIIFVVLLMVYRSVTTVILLLLTVGIEVFAARGVIAFIANN---- 221 Query 246 QLYWIVLA-----LAVILLLAVGSDYNLLLISRFKE--EIGAGLNTGIIRAMAGTGGVVT 298 W+ L+ L V L +A G+DY + R++E + G T VV Sbjct 222 --NWMALSTFAVNLLVALAMAAGTDYAIFFFGRYQEARQAGEDRQTAYFTTYRSVAPVVL 279 Query 299 AAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLV----VRAFMT---------PSI 345 +GL A M F+ + + +G +G+L L+ V A +T P+ Sbjct 280 GSGLTIAGAMLCLSFTRMPIFQTMGMPCSVGMLISVLIALTLVPAVLTVGSGFGLFDPTR 339 Query 346 AVLLGRW 352 A+ GRW Sbjct 340 AIGFGRW 346 >gi|5524337|gb|AAD44230.1|AF143772_36 TmtpC [Mycobacterium avium] Length=974 Score = 489 bits (1260), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 235/375 (63%), Positives = 295/375 (79%), Gaps = 2/375 (0%) Query 14 WMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYA 73 W +R++FDT+DG+D L +++ + LD + + P L+ P+ IA + R + L N++ Sbjct 587 WSLRNIFDTLDGVDTLSDKMIDLVRDLDHMDRLMPLLLEQYPEMIAMSEDMRNMLLTNHS 646 Query 74 TMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAAR 133 TMSGI Q + ++A AMG+AFDA+KNDDSFYLPP+ F+N DF++ + FLS DGKAAR Sbjct 647 TMSGIIGQMDSNSKDATAMGEAFDASKNDDSFYLPPDIFENADFKKAMSQFLSPDGKAAR 706 Query 134 MIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLL 193 IISH GDPAT E ++ ID I+ AA EA+K TP+ A IYLAGTA+TFKD +DG+TYDL Sbjct 707 FIISHRGDPATSEALNRIDKIRSAAEEALKNTPLENAKIYLAGTASTFKDFRDGSTYDLF 766 Query 194 IAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLA 253 IAG+ AL LI +IM+I+TRS +AAL+IVGTV LSLGASFGLSVL+WQ++ GIQLYW+VL Sbjct 767 IAGVGALCLIFIIMLILTRSFIAALIIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLP 826 Query 254 LAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVF 313 ++VI+LLAVGSDYNLLL+SR KEEI AG+NTGIIRAM GTG VVT AGLVFA TM+S V Sbjct 827 MSVIVLLAVGSDYNLLLVSRMKEEIAAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVV 886 Query 314 SDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGP 373 SDLR++GQ+GTTIGLGL+FDTL+VR+FMTP+IA L GRWFWWPQ VR RPAS++LR G Sbjct 887 SDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALFGRWFWWPQLVRRRPASQLLRSEGT 946 Query 374 RPVVRELLLREGNDD 388 R VR LL NDD Sbjct 947 RRSVRVLL--HQNDD 959 Lambda K H 0.323 0.138 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 779602889160 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40