BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1570
Length=226
Score E
Sequences producing significant alignments: (Bits) Value
gi|242556450|pdb|3FGN|A Chain A, Crystal Structure Of Dethiobiot... 430 7e-119
gi|15608708|ref|NP_216086.1| dithiobiotin synthetase [Mycobacter... 429 2e-118
gi|242556456|pdb|3FMF|A Chain A, Crystal Structure Of Mycobacter... 426 1e-117
gi|15841037|ref|NP_336074.1| dithiobiotin synthetase [Mycobacter... 426 1e-117
gi|340626591|ref|YP_004745043.1| putative dethiobiotin synthetas... 426 2e-117
gi|121637492|ref|YP_977715.1| dithiobiotin synthetase [Mycobacte... 425 3e-117
gi|289750140|ref|ZP_06509518.1| LOW QUALITY PROTEIN: dethiobioti... 425 3e-117
gi|339298179|gb|AEJ50289.1| dethiobiotin synthetase [Mycobacteri... 422 1e-116
gi|289761733|ref|ZP_06521111.1| LOW QUALITY PROTEIN: dethiobioti... 400 7e-110
gi|289569609|ref|ZP_06449836.1| dethiobiotin synthetase bioD [My... 392 2e-107
gi|289745325|ref|ZP_06504703.1| dithiobiotin synthetase [Mycobac... 371 3e-101
gi|298525081|ref|ZP_07012490.1| dethiobiotin synthetase [Mycobac... 328 3e-88
gi|118617211|ref|YP_905543.1| dithiobiotin synthetase [Mycobacte... 322 3e-86
gi|183982398|ref|YP_001850689.1| dethiobiotin synthetase BioD [M... 320 8e-86
gi|466781|gb|AAA17057.1| bioD [Mycobacterium leprae] 292 2e-77
gi|342860847|ref|ZP_08717497.1| dithiobiotin synthetase [Mycobac... 291 4e-77
gi|240167957|ref|ZP_04746616.1| dithiobiotin synthetase [Mycobac... 286 2e-75
gi|15827619|ref|NP_301882.1| dithiobiotin synthetase [Mycobacter... 276 2e-72
gi|333990801|ref|YP_004523415.1| dethiobiotin synthetase BioD [M... 268 6e-70
gi|120403774|ref|YP_953603.1| dithiobiotin synthetase [Mycobacte... 250 1e-64
gi|145224211|ref|YP_001134889.1| dithiobiotin synthetase [Mycoba... 238 3e-61
gi|126435672|ref|YP_001071363.1| dithiobiotin synthetase [Mycoba... 238 3e-61
gi|118469522|ref|YP_887504.1| dithiobiotin synthetase [Mycobacte... 235 3e-60
gi|108800042|ref|YP_640239.1| dithiobiotin synthetase [Mycobacte... 233 2e-59
gi|118462415|ref|YP_882386.1| dithiobiotin synthetase [Mycobacte... 233 2e-59
gi|41407374|ref|NP_960210.1| dithiobiotin synthetase [Mycobacter... 230 9e-59
gi|254775652|ref|ZP_05217168.1| dithiobiotin synthetase [Mycobac... 228 7e-58
gi|169629771|ref|YP_001703420.1| dithiobiotin synthetase [Mycoba... 218 5e-55
gi|254822063|ref|ZP_05227064.1| dithiobiotin synthetase [Mycobac... 217 1e-54
gi|226306990|ref|YP_002766950.1| dethiobiotin synthetase [Rhodoc... 174 1e-41
gi|229490354|ref|ZP_04384195.1| dethiobiotin synthase [Rhodococc... 172 4e-41
gi|296164452|ref|ZP_06847025.1| dethiobiotin synthetase [Mycobac... 170 2e-40
gi|333919058|ref|YP_004492639.1| Dethiobiotin synthetase [Amycol... 169 2e-40
gi|111018066|ref|YP_701038.1| dithiobiotin synthetase [Rhodococc... 165 5e-39
gi|343927136|ref|ZP_08766617.1| dethiobiotin synthetase [Gordoni... 160 1e-37
gi|54023788|ref|YP_118030.1| dithiobiotin synthetase [Nocardia f... 158 6e-37
gi|269127900|ref|YP_003301270.1| dethiobiotin synthase [Thermomo... 156 2e-36
gi|325674434|ref|ZP_08154122.1| dethiobiotin synthetase [Rhodoco... 155 3e-36
gi|312140089|ref|YP_004007425.1| dethiobiotin synthetase biod [R... 155 3e-36
gi|256396824|ref|YP_003118388.1| dithiobiotin synthetase [Catenu... 155 3e-36
gi|320012146|gb|ADW06996.1| dethiobiotin synthase [Streptomyces ... 147 1e-33
gi|134097574|ref|YP_001103235.1| dithiobiotin synthetase [Saccha... 147 1e-33
gi|294811367|ref|ZP_06770010.1| Dethiobiotin synthetase [Strepto... 145 4e-33
gi|291298002|ref|YP_003509280.1| dethiobiotin synthase [Stackebr... 143 2e-32
gi|256379739|ref|YP_003103399.1| dethiobiotin synthase [Actinosy... 140 2e-31
gi|271969505|ref|YP_003343701.1| dethiobiotin synthase [Streptos... 139 3e-31
gi|326333991|ref|ZP_08200221.1| dethiobiotin synthase [Nocardioi... 139 3e-31
gi|255324300|ref|ZP_05365421.1| dethiobiotin synthase [Corynebac... 139 3e-31
gi|25027976|ref|NP_738030.1| dithiobiotin synthetase [Corynebact... 138 5e-31
gi|213965966|ref|ZP_03394156.1| dethiobiotin synthase [Corynebac... 138 5e-31
>gi|242556450|pdb|3FGN|A Chain A, Crystal Structure Of Dethiobiotin Synthetase In Mycobacterium
Tuberculosis
gi|242556451|pdb|3FGN|B Chain B, Crystal Structure Of Dethiobiotin Synthetase In Mycobacterium
Tuberculosis
gi|242556452|pdb|3FGN|C Chain C, Crystal Structure Of Dethiobiotin Synthetase In Mycobacterium
Tuberculosis
gi|242556453|pdb|3FGN|D Chain D, Crystal Structure Of Dethiobiotin Synthetase In Mycobacterium
Tuberculosis
Length=251
Score = 430 bits (1106), Expect = 7e-119, Method: Compositional matrix adjust.
Identities = 225/226 (99%), Positives = 226/226 (100%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 26 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 85
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 86 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 145
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 146 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 205
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 206 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 251
>gi|15608708|ref|NP_216086.1| dithiobiotin synthetase [Mycobacterium tuberculosis H37Rv]
gi|148661366|ref|YP_001282889.1| dithiobiotin synthetase [Mycobacterium tuberculosis H37Ra]
gi|167967378|ref|ZP_02549655.1| dithiobiotin synthetase [Mycobacterium tuberculosis H37Ra]
gi|5915791|sp|O06620.1|BIOD_MYCTU RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|158513369|sp|A5U2S7.1|BIOD_MYCTA RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|2117267|emb|CAB09067.1| Probable dethiobiotin synthetase bioD [Mycobacterium tuberculosis
H37Rv]
gi|148505518|gb|ABQ73327.1| dithiobiotin synthetase [Mycobacterium tuberculosis H37Ra]
Length=226
Score = 429 bits (1102), Expect = 2e-118, Method: Compositional matrix adjust.
Identities = 225/226 (99%), Positives = 226/226 (100%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|242556456|pdb|3FMF|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7,8 Diaminopelargonic Acid
Carbamate
gi|242556457|pdb|3FMF|B Chain B, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7,8 Diaminopelargonic Acid
Carbamate
gi|242556458|pdb|3FMF|C Chain C, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7,8 Diaminopelargonic Acid
Carbamate
9 more sequence titles
gi|242556459|pdb|3FMF|D Chain D, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7,8 Diaminopelargonic Acid
Carbamate
gi|242556461|pdb|3FMI|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7-Keto 8-Aminopelargonic
Acid
gi|242556462|pdb|3FMI|B Chain B, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7-Keto 8-Aminopelargonic
Acid
gi|242556463|pdb|3FMI|C Chain C, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7-Keto 8-Aminopelargonic
Acid
gi|242556464|pdb|3FMI|D Chain D, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With 7-Keto 8-Aminopelargonic
Acid
gi|242556467|pdb|3FPA|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With Dethiobiotin And Phosphate
gi|242556468|pdb|3FPA|B Chain B, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With Dethiobiotin And Phosphate
gi|242556469|pdb|3FPA|C Chain C, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With Dethiobiotin And Phosphate
gi|242556470|pdb|3FPA|D Chain D, Crystal Structure Of Mycobacterium Tuberculosis Dethiobiotin
Synthetase Complexed With Dethiobiotin And Phosphate
Length=251
Score = 426 bits (1095), Expect = 1e-117, Method: Compositional matrix adjust.
Identities = 224/226 (99%), Positives = 225/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 26 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 85
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 86 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 145
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVS AGLVIGSWPDPPGLVAA
Sbjct 146 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSXAGLVIGSWPDPPGLVAA 205
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 206 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 251
>gi|15841037|ref|NP_336074.1| dithiobiotin synthetase [Mycobacterium tuberculosis CDC1551]
gi|31792756|ref|NP_855249.1| dithiobiotin synthetase [Mycobacterium bovis AF2122/97]
gi|148822793|ref|YP_001287547.1| dithiobiotin synthetase [Mycobacterium tuberculosis F11]
54 more sequence titles
Length=226
Score = 426 bits (1095), Expect = 1e-117, Method: Compositional matrix adjust.
Identities = 224/226 (99%), Positives = 225/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|340626591|ref|YP_004745043.1| putative dethiobiotin synthetase bioD [Mycobacterium canettii
CIPT 140010059]
gi|340004781|emb|CCC43925.1| putative dethiobiotin synthetase bioD [Mycobacterium canettii
CIPT 140010059]
Length=226
Score = 426 bits (1094), Expect = 2e-117, Method: Compositional matrix adjust.
Identities = 223/226 (99%), Positives = 225/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCA+LASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCASLASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|121637492|ref|YP_977715.1| dithiobiotin synthetase [Mycobacterium bovis BCG str. Pasteur
1173P2]
gi|224989967|ref|YP_002644654.1| dethiobiotin synthetase [Mycobacterium bovis BCG str. Tokyo 172]
gi|158512950|sp|A1KJ01.1|BIOD_MYCBP RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|254813135|sp|C1ANK7.1|BIOD_MYCBT RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|2791847|gb|AAB96958.1| putative dethiobiotin synthetase [Mycobacterium bovis BCG]
gi|121493139|emb|CAL71610.1| Probable dethiobiotin synthetase bioD [Mycobacterium bovis BCG
str. Pasteur 1173P2]
gi|224773080|dbj|BAH25886.1| dethiobiotin synthetase [Mycobacterium bovis BCG str. Tokyo 172]
gi|341601510|emb|CCC64183.1| probable dethiobiotin synthetase bioD [Mycobacterium bovis BCG
str. Moreau RDJ]
Length=226
Score = 425 bits (1092), Expect = 3e-117, Method: Compositional matrix adjust.
Identities = 223/226 (99%), Positives = 224/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAA ALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAVALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|289750140|ref|ZP_06509518.1| LOW QUALITY PROTEIN: dethiobiotin synthetase bioD [Mycobacterium
tuberculosis T92]
gi|289690727|gb|EFD58156.1| LOW QUALITY PROTEIN: dethiobiotin synthetase bioD [Mycobacterium
tuberculosis T92]
Length=227
Score = 425 bits (1092), Expect = 3e-117, Method: Compositional matrix adjust.
Identities = 223/226 (99%), Positives = 225/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD+LAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDELAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|339298179|gb|AEJ50289.1| dethiobiotin synthetase [Mycobacterium tuberculosis CCDC5180]
Length=226
Score = 422 bits (1086), Expect = 1e-116, Method: Compositional matrix adjust.
Identities = 223/226 (99%), Positives = 224/226 (99%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDR GRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRRGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
>gi|289761733|ref|ZP_06521111.1| LOW QUALITY PROTEIN: dethiobiotin synthetase bioD [Mycobacterium
tuberculosis GM 1503]
gi|289709239|gb|EFD73255.1| LOW QUALITY PROTEIN: dethiobiotin synthetase bioD [Mycobacterium
tuberculosis GM 1503]
Length=227
Score = 400 bits (1028), Expect = 7e-110, Method: Compositional matrix adjust.
Identities = 213/215 (99%), Positives = 214/215 (99%), Gaps = 0/215 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAA 215
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAA
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAA 215
>gi|289569609|ref|ZP_06449836.1| dethiobiotin synthetase bioD [Mycobacterium tuberculosis T17]
gi|289543363|gb|EFD47011.1| dethiobiotin synthetase bioD [Mycobacterium tuberculosis T17]
Length=210
Score = 392 bits (1008), Expect = 2e-107, Method: Compositional matrix adjust.
Identities = 207/209 (99%), Positives = 208/209 (99%), Gaps = 0/209 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFA 209
SNRSALARIA VRAALPAGAASLDAGDFA
Sbjct 181 SNRSALARIATVRAALPAGAASLDAGDFA 209
>gi|289745325|ref|ZP_06504703.1| dithiobiotin synthetase [Mycobacterium tuberculosis 02_1987]
gi|289685853|gb|EFD53341.1| dithiobiotin synthetase [Mycobacterium tuberculosis 02_1987]
Length=197
Score = 371 bits (953), Expect = 3e-101, Method: Compositional matrix adjust.
Identities = 195/197 (99%), Positives = 196/197 (99%), Gaps = 0/197 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT
Sbjct 1 MTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
Query 181 SNRSALARIAMVRAALP 197
SNRSALARIA VRAALP
Sbjct 181 SNRSALARIATVRAALP 197
>gi|298525081|ref|ZP_07012490.1| dethiobiotin synthetase [Mycobacterium tuberculosis 94_M4241A]
gi|298494875|gb|EFI30169.1| dethiobiotin synthetase [Mycobacterium tuberculosis 94_M4241A]
Length=232
Score = 328 bits (842), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 205/226 (91%), Positives = 207/226 (92%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
V+T GTG K V C L AA QAGIDVAVC P+QTG ARG DDLAEVGRLAGVT
Sbjct 7 FHFCVLTDPGTGSRKFVFCTVLVFAAGQAGIDVAVCNPIQTGPARGADDLAEVGRLAGVT 66
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP
Sbjct 67 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 126
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA
Sbjct 127 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 186
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNRSALARIA VRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG
Sbjct 187 SNRSALARIATVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 232
>gi|118617211|ref|YP_905543.1| dithiobiotin synthetase [Mycobacterium ulcerans Agy99]
gi|158512384|sp|A0PP03.1|BIOD_MYCUA RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|118569321|gb|ABL04072.1| dethiobiotin synthetase BioD [Mycobacterium ulcerans Agy99]
Length=226
Score = 322 bits (824), Expect = 3e-86, Method: Compositional matrix adjust.
Identities = 171/226 (76%), Positives = 187/226 (83%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+L VTGT TGVGKTVV AALAS A QAGIDV VCKPVQTGT GDDDLAE+GRL+GVT
Sbjct 1 MTVLCVTGTCTGVGKTVVTAALASQANQAGIDVVVCKPVQTGTGNGDDDLAEIGRLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+L GLARYP PMAP AAAE AG LP+RDQ+V+ I LDRPGRLTLVEGAGGLLVELA+
Sbjct 61 ELVGLARYPLPMAPVAAAEQAGQPLPSRDQLVQHIRGLDRPGRLTLVEGAGGLLVELADS 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
G TLRD+AVD+ AA LVVV A LGTLNHT LTLEALAAQ+VSCAGLV+GSWP PGLV +
Sbjct 121 GGTLRDLAVDLGAAMLVVVAAGLGTLNHTALTLEALAAQKVSCAGLVLGSWPAHPGLVES 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNR ALAR+A +RA L AGAA L DFA MSA AFDR WVA LVG
Sbjct 181 SNRDALARLAPMRAVLSAGAAQLSVADFAVMSAGAFDREWVATLVG 226
>gi|183982398|ref|YP_001850689.1| dethiobiotin synthetase BioD [Mycobacterium marinum M]
gi|226698975|sp|B2HQ91.1|BIOD_MYCMM RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|183175724|gb|ACC40834.1| dethiobiotin synthetase BioD [Mycobacterium marinum M]
Length=226
Score = 320 bits (821), Expect = 8e-86, Method: Compositional matrix adjust.
Identities = 171/226 (76%), Positives = 187/226 (83%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+L VTGT TGVGKTVV AALAS A QAGIDV VCKPVQTGT GDDDLAE+GRL+GVT
Sbjct 1 MTVLCVTGTCTGVGKTVVTAALASQANQAGIDVVVCKPVQTGTGIGDDDLAEIGRLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+L GLARYP PMAP AAAE AG LP+RDQ+V+ I LDRPGRLTLVEGAGGLLVELA+
Sbjct 61 ELVGLARYPLPMAPVAAAEQAGQPLPSRDQLVQHIRGLDRPGRLTLVEGAGGLLVELADS 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
G TLRD+AVD+ AA LVVV A LGTLNHT LTLEALAAQ+VSCAGLV+GSWP PGLV +
Sbjct 121 GGTLRDLAVDLGAAMLVVVAAGLGTLNHTALTLEALAAQKVSCAGLVLGSWPAHPGLVES 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNR ALAR+A +RA L AGAA L DFA MSA AFDR WVA LVG
Sbjct 181 SNRDALARLAPMRAVLSAGAAQLSVADFAVMSAGAFDREWVATLVG 226
>gi|466781|gb|AAA17057.1| bioD [Mycobacterium leprae]
Length=223
Score = 292 bits (748), Expect = 2e-77, Method: Compositional matrix adjust.
Identities = 166/222 (75%), Positives = 186/222 (84%), Gaps = 0/222 (0%)
Query 4 LVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLA 63
+VVTGT TGVGKTV CAALA ARQAGI+VAVCKPVQTGT GDDDLAEV RL+GVT+L
Sbjct 1 MVVTGTDTGVGKTVACAALACHARQAGIEVAVCKPVQTGTQIGDDDLAEVARLSGVTELT 60
Query 64 GLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVT 123
GL RYPQP+APAAAAEHAGMALP R+Q++ LIA LDRPGRL LVEGAGGLLVELA+ T
Sbjct 61 GLVRYPQPLAPAAAAEHAGMALPTREQLLELIAGLDRPGRLILVEGAGGLLVELADASAT 120
Query 124 LRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNR 183
LRD+AV++ A ALV V+ +LGTLNHT LTLEAL + V+CAGLVIGSW PG V SNR
Sbjct 121 LRDLAVELGALALVTVSVELGTLNHTALTLEALTTRGVACAGLVIGSWTGRPGAVQISNR 180
Query 184 SALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
SALAR+A +RA LPAGA S+DA DFAAMSAAAFDR+WV LV
Sbjct 181 SALARLAPMRATLPAGAGSMDATDFAAMSAAAFDRDWVTTLV 222
>gi|342860847|ref|ZP_08717497.1| dithiobiotin synthetase [Mycobacterium colombiense CECT 3035]
gi|342131871|gb|EGT85128.1| dithiobiotin synthetase [Mycobacterium colombiense CECT 3035]
Length=226
Score = 291 bits (746), Expect = 4e-77, Method: Compositional matrix adjust.
Identities = 160/226 (71%), Positives = 183/226 (81%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+LVVTGT TGVGKTV AALA ARQAG+DVAVCKPVQTGT GDDDLAEV RL+GVT
Sbjct 1 MTVLVVTGTDTGVGKTVATAALACHARQAGLDVAVCKPVQTGTDAGDDDLAEVARLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAG RYPQP+AP AAAE AGM LP R+Q++ L+ +LDRPGRLTLVEGAGGLLVEL E
Sbjct 61 ELAGFGRYPQPLAPVAAAEAAGMPLPTREQLLALVGELDRPGRLTLVEGAGGLLVELGEN 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVT RD+AV + AA LVVV LGTLNHT LTLE++AAQ +SCAGLVIGSWP PG+V
Sbjct 121 GVTARDLAVALGAAVLVVVGPSLGTLNHTALTLESIAAQGLSCAGLVIGSWPRRPGVVET 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
+NR AL R+A VRA LP GAASL +FAA+ + AFDR+WV LVG
Sbjct 181 TNRQALDRLAAVRAVLPEGAASLGPTEFAALCSRAFDRDWVTSLVG 226
>gi|240167957|ref|ZP_04746616.1| dithiobiotin synthetase [Mycobacterium kansasii ATCC 12478]
Length=224
Score = 286 bits (731), Expect = 2e-75, Method: Compositional matrix adjust.
Identities = 172/225 (77%), Positives = 189/225 (84%), Gaps = 2/225 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+L+VTGT TGVGKT+ AALAS ARQAGIDVAVCKPVQTGT GDDDLAEVGR++GVT
Sbjct 1 MTVLLVTGTDTGVGKTIASAALASHARQAGIDVAVCKPVQTGTGAGDDDLAEVGRMSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAGLARYP PMAPAAAA+ AGMALPARDQ+++LI LDRPGRLTLVEGAGGLLV+LA+
Sbjct 61 ELAGLARYPLPMAPAAAAQQAGMALPARDQVLQLIRSLDRPGRLTLVEGAGGLLVDLADG 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRD+ V + AA LVVV A LGTLNHT LTLEALAAQ VSCAGLVIGSWP P LV
Sbjct 121 GVTLRDLGVALPAAVLVVVGAGLGTLNHTALTLEALAAQGVSCAGLVIGSWPAHPSLVET 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
SNR ALAR+A VRA LPAGA A DFAA+SAAAFD WV LV
Sbjct 181 SNREALARMAPVRAVLPAGAGV--AEDFAAISAAAFDPEWVRTLV 223
>gi|15827619|ref|NP_301882.1| dithiobiotin synthetase [Mycobacterium leprae TN]
gi|221230096|ref|YP_002503512.1| dithiobiotin synthetase [Mycobacterium leprae Br4923]
gi|13432113|sp|P45486.2|BIOD_MYCLE RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|254813136|sp|B8ZR85.1|BIOD_MYCLB RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|13093170|emb|CAC31599.1| dethiobiotin synthase [Mycobacterium leprae]
gi|219933203|emb|CAR71313.1| dethiobiotin synthase [Mycobacterium leprae Br4923]
Length=226
Score = 276 bits (705), Expect = 2e-72, Method: Compositional matrix adjust.
Identities = 157/211 (75%), Positives = 176/211 (84%), Gaps = 0/211 (0%)
Query 15 KTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAP 74
KTV CAALA ARQAGI+VAVCKPVQTGT GDDDLAEV RL+GVT+L GL RYPQP+AP
Sbjct 15 KTVACAALACHARQAGIEVAVCKPVQTGTQIGDDDLAEVARLSGVTELTGLVRYPQPLAP 74
Query 75 AAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAA 134
AAAAEHAGMALP R+Q++ LIA LDRPGRL LVEGAGGLLVELA+ TLRD+AV++ A
Sbjct 75 AAAAEHAGMALPTREQLLELIAGLDRPGRLILVEGAGGLLVELADASATLRDLAVELGAL 134
Query 135 ALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRA 194
ALV V+ +LGTLNHT LTLEAL + V+CAGLVIGSW PG V SNRSALAR+A +RA
Sbjct 135 ALVTVSVELGTLNHTALTLEALTTRGVACAGLVIGSWTGRPGAVQISNRSALARLAPMRA 194
Query 195 ALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
LPAGA S+DA DFAAMSAAAFDR+WV LV
Sbjct 195 TLPAGAGSMDATDFAAMSAAAFDRDWVTTLV 225
>gi|333990801|ref|YP_004523415.1| dethiobiotin synthetase BioD [Mycobacterium sp. JDM601]
gi|333486769|gb|AEF36161.1| dethiobiotin synthetase BioD [Mycobacterium sp. JDM601]
Length=222
Score = 268 bits (684), Expect = 6e-70, Method: Compositional matrix adjust.
Identities = 145/210 (70%), Positives = 162/210 (78%), Gaps = 0/210 (0%)
Query 17 VVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAA 76
+ AALA ARQAG++VAV KPVQTGTA GDDDLAEVGRL+GVT L G ARYP+P+AP A
Sbjct 13 IATAALAGCARQAGLEVAVVKPVQTGTADGDDDLAEVGRLSGVTDLFGTARYPEPLAPVA 72
Query 77 AAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAAL 136
AAE AGMALP +++ I DRPGRLTLVEGAGGLLVELA GVTLRD+AVD+ AA L
Sbjct 73 AAEQAGMALPTGAELLAAIRAADRPGRLTLVEGAGGLLVELAADGVTLRDLAVDLGAAVL 132
Query 137 VVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAAL 196
VVV A+LGTLNHT LTLE+LA Q +SCAGLVIGSWP PG AA NR+AL R+A VRA L
Sbjct 133 VVVNAELGTLNHTALTLESLAGQGLSCAGLVIGSWPGQPGPAAAGNRAALGRLAPVRAVL 192
Query 197 PAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
P G LDA F+ MS AFD WV LVG
Sbjct 193 PEGCGRLDASQFSGMSRTAFDTGWVRSLVG 222
>gi|120403774|ref|YP_953603.1| dithiobiotin synthetase [Mycobacterium vanbaalenii PYR-1]
gi|158513016|sp|A1T8U7.1|BIOD_MYCVP RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|119956592|gb|ABM13597.1| dethiobiotin synthase [Mycobacterium vanbaalenii PYR-1]
Length=226
Score = 250 bits (638), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 137/205 (67%), Positives = 153/205 (75%), Gaps = 0/205 (0%)
Query 20 AALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAE 79
AALA AR GIDVAVCKPVQTGT GDDDLAEV RLAGVT+L LAR+P+P+AP AAA
Sbjct 20 AALACHARLHGIDVAVCKPVQTGTRDGDDDLAEVARLAGVTELHSLARFPEPLAPLAAAR 79
Query 80 HAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVV 139
+G LP R QI+ LI DRPGRLTLVEGAGGLLVE+A G TLRDVA D+ A L VV
Sbjct 80 RSGAELPTRAQILDLITAADRPGRLTLVEGAGGLLVEIASDGSTLRDVAADLGAPVLTVV 139
Query 140 TADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAG 199
LGTLNHT LTLEALA +Q+S AGLVIG+WP PG+ NR AL+R+A VRAALPAG
Sbjct 140 APGLGTLNHTVLTLEALAHRQISSAGLVIGAWPAQPGVAEIDNRDALSRLAPVRAALPAG 199
Query 200 AASLDAGDFAAMSAAAFDRNWVAGL 224
A SL DF +S AFD +WV GL
Sbjct 200 AGSLGRADFERLSVDAFDPSWVEGL 224
>gi|145224211|ref|YP_001134889.1| dithiobiotin synthetase [Mycobacterium gilvum PYR-GCK]
gi|315444545|ref|YP_004077424.1| dethiobiotin synthase [Mycobacterium sp. Spyr1]
gi|189081440|sp|A4T9L2.1|BIOD_MYCGI RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|145216697|gb|ABP46101.1| dethiobiotin synthase [Mycobacterium gilvum PYR-GCK]
gi|315262848|gb|ADT99589.1| dethiobiotin synthase [Mycobacterium sp. Spyr1]
Length=226
Score = 238 bits (608), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 133/209 (64%), Positives = 150/209 (72%), Gaps = 0/209 (0%)
Query 18 VCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAA 77
V AALA AR AG+DVAVCKP+QTGT GDDDLA V RLAGV L LA++P+P+AP AA
Sbjct 18 VTAALACHARLAGLDVAVCKPIQTGTRDGDDDLAVVARLAGVEDLHSLAKFPEPLAPLAA 77
Query 78 AEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALV 137
A AG LP+R + LIA +DRPGRLTLVEGAGGLLVE+ GVTLRD+A D+ A L
Sbjct 78 AHRAGADLPSRAALDDLIAAVDRPGRLTLVEGAGGLLVEIGRGGVTLRDLAEDLRAPVLT 137
Query 138 VVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALP 197
VV LGTLNHT LTLEALA + V GLVIGSWP PG+ NR ALAR+ VRAALP
Sbjct 138 VVAPGLGTLNHTVLTLEALAHRDVRSEGLVIGSWPAQPGVAEIDNRDALARLGPVRAALP 197
Query 198 AGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
AGA +L DF +S AFD WV GLVG
Sbjct 198 AGAGTLSGTDFERLSVQAFDEAWVRGLVG 226
>gi|126435672|ref|YP_001071363.1| dithiobiotin synthetase [Mycobacterium sp. JLS]
gi|158513455|sp|A3Q145.1|BIOD_MYCSJ RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|126235472|gb|ABN98872.1| dethiobiotin synthase [Mycobacterium sp. JLS]
Length=229
Score = 238 bits (608), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 151/229 (66%), Positives = 171/229 (75%), Gaps = 4/229 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARG----DDDLAEVGRL 56
+++LV+TGT TGVGKTV AALA AAR AGIDVAVCKPVQTGT DDDL E+GRL
Sbjct 1 MSVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPAGGTGDDDLVEIGRL 60
Query 57 AGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVE 116
AGV L RYP P+AP AAAE AG ALP RD+++ +I D PGRLTLVEGAGGLLVE
Sbjct 61 AGVDALHPGWRYPDPLAPVAAAERAGAALPTRDELIGMIRAADAPGRLTLVEGAGGLLVE 120
Query 117 LAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPG 176
L + VTLRDVA ++AA LVVV LGTLNHT LTLE+LAAQQV CAGLVIG+WP PG
Sbjct 121 LGQDAVTLRDVATELAAPVLVVVAPGLGTLNHTALTLESLAAQQVPCAGLVIGAWPAQPG 180
Query 177 LVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
NR ALAR+A VRAALPAG S+ DF +SA AFD NW+AGL+
Sbjct 181 AAEIDNRDALARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL 229
>gi|118469522|ref|YP_887504.1| dithiobiotin synthetase [Mycobacterium smegmatis str. MC2 155]
gi|158512469|sp|A0QX66.1|BIOD_MYCS2 RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|118170809|gb|ABK71705.1| dethiobiotin synthase [Mycobacterium smegmatis str. MC2 155]
Length=225
Score = 235 bits (600), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 139/224 (63%), Positives = 162/224 (73%), Gaps = 0/224 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+L VTGT TGVGKTV AALA AAR A DVAVCKPVQTGT GDDDL EV RL+GVT
Sbjct 1 MTVLAVTGTDTGVGKTVTTAALACAARLARRDVAVCKPVQTGTIDGDDDLGEVRRLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
L G RYP+P+AP AAA AG LP R ++V + +D GRLT+VEGAGGLLV L
Sbjct 61 ALHGGWRYPEPLAPVAAAGRAGAPLPTRTELVGSVRAVDAAGRLTIVEGAGGLLVALGAD 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVTLRD+A D+ A L+VV+ LGTLNHT LTLEALAA +SCAGLVIG+WP PG+
Sbjct 121 GVTLRDLAHDLGAQVLIVVSPGLGTLNHTALTLEALAAHGLSCAGLVIGAWPAEPGVAEL 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGL 224
NR+AL +A VRA LPAGA + F A+SAAAFD +W+ L
Sbjct 181 DNRTALEALAPVRAVLPAGAGAASPERFEALSAAAFDADWITSL 224
>gi|108800042|ref|YP_640239.1| dithiobiotin synthetase [Mycobacterium sp. MCS]
gi|119869168|ref|YP_939120.1| dithiobiotin synthetase [Mycobacterium sp. KMS]
gi|123178596|sp|Q1B7F1.1|BIOD_MYCSS RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|158513064|sp|A1UHM2.1|BIOD_MYCSK RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|108770461|gb|ABG09183.1| dethiobiotin synthase [Mycobacterium sp. MCS]
gi|119695257|gb|ABL92330.1| dethiobiotin synthase [Mycobacterium sp. KMS]
Length=229
Score = 233 bits (593), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 147/229 (65%), Positives = 168/229 (74%), Gaps = 4/229 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARG----DDDLAEVGRL 56
+++LV+TGT TGVGKTV AALA AAR AGIDVAVCKPVQTGT DDDL E+GRL
Sbjct 1 MSVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRL 60
Query 57 AGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVE 116
AGV L RYP P+AP AAAE AG ALP RD+++ ++ D PGRLTLVEGAGGLLVE
Sbjct 61 AGVDALHPGWRYPDPLAPVAAAERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVE 120
Query 117 LAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPG 176
L + VTLRDVA ++ A LVVV LGTLNHT LTLE+LAAQ V CAGLVIG+WP PG
Sbjct 121 LGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESLAAQHVPCAGLVIGAWPAQPG 180
Query 177 LVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
NR LAR+A VRAALPAG S+ DF +SA AFD NW+AGL+
Sbjct 181 AAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL 229
>gi|118462415|ref|YP_882386.1| dithiobiotin synthetase [Mycobacterium avium 104]
gi|158512439|sp|A0QHJ8.1|BIOD_MYCA1 RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|118163702|gb|ABK64599.1| dethiobiotin synthase [Mycobacterium avium 104]
Length=226
Score = 233 bits (593), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 164/226 (73%), Positives = 186/226 (83%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+LVVTGT TGVGKTV AALA AR+AGIDVAVCKPVQTGT GDDDLAEV RL+GVT
Sbjct 1 MTVLVVTGTDTGVGKTVATAALACHARRAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAGLARYP+P+AP AAA AGMALP+R+Q++R I +LDRPGRLTLVEGAGGLLVEL E
Sbjct 61 ELAGLARYPRPLAPVAAAAAAGMALPSREQLLRFIGELDRPGRLTLVEGAGGLLVELGEN 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVT RD+AV + AA LVVV LGTLNHT LTLEALAAQ +SCAGLVIG+WP+ PG V
Sbjct 121 GVTARDLAVALGAAVLVVVRPALGTLNHTALTLEALAAQGLSCAGLVIGAWPEHPGPVET 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNR AL +A VRA LPAGAA+L A +F A+SA AFDR+WV L G
Sbjct 181 SNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG 226
>gi|41407374|ref|NP_960210.1| dithiobiotin synthetase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41395726|gb|AAS03593.1| BioD [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336457927|gb|EGO36918.1| dethiobiotin synthase [Mycobacterium avium subsp. paratuberculosis
S397]
Length=235
Score = 230 bits (587), Expect = 9e-59, Method: Compositional matrix adjust.
Identities = 164/226 (73%), Positives = 185/226 (82%), Gaps = 0/226 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+LVVTGT TGVGKTV AALA ARQAGIDVAVCKPVQTGT GDDDLAEV RL+GVT
Sbjct 10 VTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVT 69
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAGLARYP+P+AP AAA AGMALP+R+Q++ I +LDRPGRLTLVEGAGGLLVEL E
Sbjct 70 ELAGLARYPRPLAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAGGLLVELGEN 129
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVT RD+AV + AA LVVV LGTLNHT LTLEALAAQ +SCAGLVIG+WP+ PG V
Sbjct 130 GVTARDLAVALGAAVLVVVRPALGTLNHTALTLEALAAQGLSCAGLVIGAWPEHPGPVET 189
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 226
SNR AL +A VRA LPAGAA+L A +F A+SA AFDR+WV L G
Sbjct 190 SNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG 235
>gi|254775652|ref|ZP_05217168.1| dithiobiotin synthetase [Mycobacterium avium subsp. avium ATCC
25291]
Length=226
Score = 228 bits (580), Expect = 7e-58, Method: Compositional matrix adjust.
Identities = 162/224 (73%), Positives = 184/224 (83%), Gaps = 0/224 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+LVVTGT TGVGKTV AALA AR+AGIDVAVCKPVQTGT GDDDLAEV RL+GVT
Sbjct 1 MTVLVVTGTDTGVGKTVATAALACHARRAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAGLARYP+P+AP AAA AGMALP+R+Q++ I +LDRPGRLTLVEGAGGLLVEL E
Sbjct 61 ELAGLARYPRPLAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAGGLLVELGEN 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
GVT RD+AV + AA LVVV LGTLNHT LTLEALAAQ +SCAGLVIG+WP+ PG V
Sbjct 121 GVTARDLAVALGAAVLVVVRPALGTLNHTALTLEALAAQGLSCAGLVIGAWPEHPGPVET 180
Query 181 SNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGL 224
SNR AL +A VRA LPAGAA+L A +F A+SA AFDR+WV L
Sbjct 181 SNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTAL 224
>gi|169629771|ref|YP_001703420.1| dithiobiotin synthetase [Mycobacterium abscessus ATCC 19977]
gi|226698974|sp|B1MBZ5.1|BIOD_MYCA9 RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|169241738|emb|CAM62766.1| Dethiobiotin synthetase (BioD) [Mycobacterium abscessus]
Length=225
Score = 218 bits (555), Expect = 5e-55, Method: Compositional matrix adjust.
Identities = 136/227 (60%), Positives = 156/227 (69%), Gaps = 5/227 (2%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+TIL+VTGT TGVGKTV AALA+AA + GIDV VCKPVQTG D D EV RL+GVT
Sbjct 1 MTILLVTGTSTGVGKTVATAALAAAAVRQGIDVTVCKPVQTG---DDHDAGEVARLSGVT 57
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
++ L RYP+P+AP A+A AG+ L Q+ I LDRPG LTLVEGAGGLLVELA
Sbjct 58 RVQTLVRYPEPLAPVASASRAGLELLDHTQMATAIVALDRPGALTLVEGAGGLLVELAAD 117
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
G TLRD+A+ + A LVV TADLGTLNHT LTLEALA Q V CAGLV+GS+P P L
Sbjct 118 GKTLRDLAMVLDAPVLVVTTADLGTLNHTALTLEALAVQSVPCAGLVVGSFPAEPDLAQR 177
Query 181 SNRSALARI--AMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
NR LA VRA +P GAA L FA +S F+ WVAGLV
Sbjct 178 LNRENLANQFGTPVRAVIPEGAARLMPPVFAELSIELFEPQWVAGLV 224
>gi|254822063|ref|ZP_05227064.1| dithiobiotin synthetase [Mycobacterium intracellulare ATCC 13950]
Length=162
Score = 217 bits (552), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 123/162 (76%), Positives = 138/162 (86%), Gaps = 0/162 (0%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
+T+LVVTGT TGVGKTVV AALA AR+AG+DVAVCKPVQTGT GDDDLAEVGRL+GVT
Sbjct 1 MTVLVVTGTDTGVGKTVVTAALACHARRAGLDVAVCKPVQTGTDDGDDDLAEVGRLSGVT 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+LAG ARYPQP+AP AAAE AGM LP R+Q++ LI +LDRPGRLTLVEGAGGLLVEL E
Sbjct 61 ELAGFARYPQPLAPVAAAEQAGMPLPTREQLLALIGELDRPGRLTLVEGAGGLLVELGEN 120
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVS 162
GVT RD+AV + A ALVVV+ LGTLNHT LTLE+LAA VS
Sbjct 121 GVTARDLAVALGAPALVVVSPSLGTLNHTALTLESLAAHNVS 162
>gi|226306990|ref|YP_002766950.1| dethiobiotin synthetase [Rhodococcus erythropolis PR4]
gi|259585555|sp|C1A0S6.1|BIOD_RHOE4 RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|226186107|dbj|BAH34211.1| dethiobiotin synthetase [Rhodococcus erythropolis PR4]
Length=227
Score = 174 bits (440), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 116/224 (52%), Positives = 142/224 (64%), Gaps = 6/224 (2%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGT-ARGDDDLAEVGRLAG- 58
++I +VTGT T VGKTVV AALAS A Q+G VAV KP QTG G DLAE+ RL G
Sbjct 1 MSIFLVTGTSTDVGKTVVTAALASVALQSGKSVAVLKPAQTGVDVDGAGDLAEIERLTGG 60
Query 59 -VTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVEL 117
VT L LARYP+P+AP AA +G+ L A D +VR+ DLD LTL+EGAGGLLV L
Sbjct 61 GVT-LVELARYPEPLAPDTAARRSGLPLLALDDVVRVARDLDTTHDLTLIEGAGGLLVRL 119
Query 118 AEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGL 177
G T RD+A +AA ++VV + LGTLNHT LT+EAL A V CAGLVIGSWP P L
Sbjct 120 GVDGFTARDLAAALAAPVVLVVASGLGTLNHTALTVEALGASGVECAGLVIGSWPQEPDL 179
Query 178 VAASNRSALARIAMV--RAALPAGAASLDAGDFAAMSAAAFDRN 219
NR L ++ V +PAG+ S +FA + A ++
Sbjct 180 AERCNREDLVSVSGVPLLGLMPAGSGSESVQEFAQTAWGALGKS 223
>gi|229490354|ref|ZP_04384195.1| dethiobiotin synthase [Rhodococcus erythropolis SK121]
gi|229322644|gb|EEN88424.1| dethiobiotin synthase [Rhodococcus erythropolis SK121]
Length=227
Score = 172 bits (435), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 113/213 (54%), Positives = 137/213 (65%), Gaps = 4/213 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGT-ARGDDDLAEVGRLAGV 59
++IL+VTGT T VGKTVV AALAS A Q+G VAV KP QTG G DLAE+ RL G
Sbjct 1 MSILLVTGTSTDVGKTVVTAALASLALQSGKSVAVLKPAQTGVDVDGAGDLAEIERLTGG 60
Query 60 -TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELA 118
L LARYP+P+AP AA +G+ L A D +VR+ +DLD LTL+EGAGGLLV L
Sbjct 61 GATLVELARYPEPLAPDTAARRSGLPLLALDDVVRVASDLDTTHDLTLIEGAGGLLVRLG 120
Query 119 EPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLV 178
G T RD+A +AA ++VV + LGTLNHT LT+EAL A V CAGLVIGSWP P L
Sbjct 121 VDGFTARDLAAALAAPVVLVVASGLGTLNHTALTVEALRASGVDCAGLVIGSWPQEPDLA 180
Query 179 AASNRSALARIAMV--RAALPAGAASLDAGDFA 209
NR L ++ V +PAG+ +FA
Sbjct 181 ERCNREDLVSVSGVPLLGVMPAGSGGASVREFA 213
>gi|296164452|ref|ZP_06847025.1| dethiobiotin synthetase [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295900186|gb|EFG79619.1| dethiobiotin synthetase [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=160
Score = 170 bits (430), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 119/159 (75%), Positives = 130/159 (82%), Gaps = 0/159 (0%)
Query 67 RYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRD 126
RYPQP+APAAAAE AG LP +Q++RLIA LDRPGRLTLVEGAGGLLVELA GVTLRD
Sbjct 1 RYPQPLAPAAAAELAGAPLPTGEQVLRLIAGLDRPGRLTLVEGAGGLLVELAAAGVTLRD 60
Query 127 VAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSAL 186
+A ++ AAALV VTA+LGTLNHT LTLEALAA VSCAGLVIGSWP+ PGL SNR AL
Sbjct 61 LAAELGAAALVAVTAELGTLNHTALTLEALAAHNVSCAGLVIGSWPERPGLAETSNRVAL 120
Query 187 ARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
R+ VRAALPAGA S+ A FAAMSAAAFDR WV LV
Sbjct 121 DRLRPVRAALPAGAGSMGAARFAAMSAAAFDRGWVTALV 159
>gi|333919058|ref|YP_004492639.1| Dethiobiotin synthetase [Amycolicicoccus subflavus DQS3-9A1]
gi|333481279|gb|AEF39839.1| Dethiobiotin synthetase [Amycolicicoccus subflavus DQS3-9A1]
Length=243
Score = 169 bits (429), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 107/223 (48%), Positives = 132/223 (60%), Gaps = 3/223 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARG-DDDLAEVGRLAGV 59
+++LVVTGT TGVGKTVV A LA AR G+ VAVCKP QTG G DLAEV RLAG
Sbjct 1 MSVLVVTGTSTGVGKTVVTAGLAVLARSRGLSVAVCKPAQTGIEDGAPGDLAEVTRLAGD 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
++ LARYP+P+AP AA +G + +IV IA L+ L LVEGAGG+LVEL +
Sbjct 61 VPVSELARYPEPLAPFTAARRSGRPMLKVGEIVTEIARLEAAHDLVLVEGAGGVLVELGQ 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TLRDVA A ++V LGTLNHT LT+EAL V C G+V+G+ P+ P L
Sbjct 121 GGFTLRDVARAANADVVLVAAPGLGTLNHTALTVEALERSDVRCTGIVVGALPEEPDLAM 180
Query 180 ASNRSALARIA--MVRAALPAGAASLDAGDFAAMSAAAFDRNW 220
N L RI + LP G + +FA A F +
Sbjct 181 RCNLDDLPRITGIPIVGVLPDGCGEWTSAEFARGVGAWFTSEF 223
>gi|111018066|ref|YP_701038.1| dithiobiotin synthetase [Rhodococcus jostii RHA1]
gi|122956068|sp|Q0SHV6.1|BIOD_RHOSR RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|110817596|gb|ABG92880.1| dethiobiotin synthetase [Rhodococcus jostii RHA1]
Length=231
Score = 165 bits (417), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 117/224 (53%), Positives = 147/224 (66%), Gaps = 3/224 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
++ILVVTGT T VGKTVV AALA+AAR+AG+ VAVCKP QTG A G DLAEV RL+GV
Sbjct 1 MSILVVTGTSTDVGKTVVTAALAAAAREAGLSVAVCKPAQTGVAPGGPGDLAEVTRLSGV 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
T + LARYP+P+AP AA +G+ + +V + LD L LVEGAGGLLV L
Sbjct 61 TAVVELARYPEPLAPDTAARRSGLPMLRCADVVETVRALDDGHDLVLVEGAGGLLVRLGA 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TL D+A + A A+VV A LGTLNHT+LT+ AL+A ++CAG VIGSWPD PGL
Sbjct 121 EGFTLVDLARALDAPAVVVAAAGLGTLNHTELTIRALSAAGLACAGTVIGSWPDEPGLAE 180
Query 180 ASNRSALARIAMVR--AALPAGAASLDAGDFAAMSAAAFDRNWV 221
N L + V ++PAG+ L + F A ++ FD W+
Sbjct 181 RCNLDDLPAVTGVDVVGSVPAGSGRLASASFGAAASTWFDSTWL 224
>gi|343927136|ref|ZP_08766617.1| dethiobiotin synthetase [Gordonia alkanivorans NBRC 16433]
gi|343762948|dbj|GAA13543.1| dethiobiotin synthetase [Gordonia alkanivorans NBRC 16433]
Length=250
Score = 160 bits (406), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 114/229 (50%), Positives = 136/229 (60%), Gaps = 11/229 (4%)
Query 3 ILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGVTQ 61
+L VTGT T VGKTVV AALA+A R VA+CKPVQTG A + DLAEV RLAG
Sbjct 12 VLAVTGTSTDVGKTVVTAALAAAGRMD--TVAICKPVQTGVAPTEPGDLAEVVRLAGDVS 69
Query 62 LAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPG 121
RYP+P+AP AA AGM L IVR + DL LTLVEGAGG+LV L E
Sbjct 70 AVESYRYPEPLAPDTAARRAGMPLADPSVIVRAVDDLAATHDLTLVEGAGGVLVRLGE-S 128
Query 122 VTLRDVAV-----DVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPG 176
T+ D+A D ++VV LG LNH +LT+ A+ A+ + AGLVIG WP+ P
Sbjct 129 ATILDIAAETLVPDTGDGVVIVVAPGLGALNHAELTVNAVRARGLRPAGLVIGWWPEEPD 188
Query 177 LVAASNRSALARIA--MVRAALPAGAASLDAGDFAAMSAAAFDRNWVAG 223
L NRS L RI V LPAGAASLD +F + FD +W+AG
Sbjct 189 LAMRCNRSDLPRITGVPVVGVLPAGAASLDPAEFRRTAPTWFDPDWLAG 237
>gi|54023788|ref|YP_118030.1| dithiobiotin synthetase [Nocardia farcinica IFM 10152]
gi|81602871|sp|Q5YYS5.1|BIOD_NOCFA RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|54015296|dbj|BAD56666.1| putative dethiobiotin synthetase [Nocardia farcinica IFM 10152]
Length=243
Score = 158 bits (399), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 110/223 (50%), Positives = 132/223 (60%), Gaps = 7/223 (3%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
+ L+VTGT T VGKTVV AAL + AR + VAVCKP QTG A G+ DLAEV RLAG
Sbjct 1 MNTLLVTGTSTDVGKTVVTAALTALARAEALPVAVCKPAQTGVAPGEPGDLAEVRRLAGP 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
LARYP+P+AP AA G L D+ + LD LT+VEGAGGLLV + E
Sbjct 61 VPTLELARYPEPLAPDTAARRCGAPLLTLDETATAVRGLD--AELTVVEGAGGLLVRIGE 118
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
TL D+A ++ A LVV A LGTLNHT+LT+ AL A V CAG+VIG+WP P L +
Sbjct 119 --FTLLDLARELDAPVLVVAAAGLGTLNHTELTIRALDAAGVRCAGVVIGAWPAEPDLAS 176
Query 180 ASNRSALARIAMVR--AALPAGAASLDAGDFAAMSAAAFDRNW 220
NR L R+ V A+PAG + D F A F W
Sbjct 177 VCNREDLPRLTGVPIVGAVPAGVGAWDHDRFTAAVPGWFAPGW 219
>gi|269127900|ref|YP_003301270.1| dethiobiotin synthase [Thermomonospora curvata DSM 43183]
gi|268312858|gb|ACY99232.1| dethiobiotin synthase [Thermomonospora curvata DSM 43183]
Length=240
Score = 156 bits (395), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 102/207 (50%), Positives = 123/207 (60%), Gaps = 3/207 (1%)
Query 5 VVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGVTQLA 63
+VTGT TGVGKT+V AALA+ AR G VAV KP QTG + DL V RLAGV L
Sbjct 1 MVTGTCTGVGKTIVTAALATVARARGASVAVVKPGQTGVGPDEPGDLDVVRRLAGVEDLH 60
Query 64 GLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVT 123
AR+P P++PAAAA AG+ + I +L RL LVEGAGGLLV + G T
Sbjct 61 EFARFPDPLSPAAAARRAGVPPLRLSDVAERIGELAETRRLVLVEGAGGLLVRYDDDGTT 120
Query 124 LRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNR 183
D+A + AA +VV DLGTLNHT LTLEA+A + V AG+VIG WP P L SN
Sbjct 121 FADLARWLHAAMVVVTRPDLGTLNHTALTLEAMAHRGVQLAGVVIGQWPREPDLAMRSNI 180
Query 184 SALARIAM--VRAALPAGAASLDAGDF 208
+ L I+ + LP A LD +F
Sbjct 181 TDLETISARPLAGVLPEAAGRLDPAEF 207
>gi|325674434|ref|ZP_08154122.1| dethiobiotin synthetase [Rhodococcus equi ATCC 33707]
gi|325554694|gb|EGD24368.1| dethiobiotin synthetase [Rhodococcus equi ATCC 33707]
Length=231
Score = 155 bits (393), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 114/228 (50%), Positives = 143/228 (63%), Gaps = 3/228 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTG-TARGDDDLAEVGRLAGV 59
+++LV++GT T VGKTVV AALA+A R AG VAVCKP QTG T DLAEV RL+GV
Sbjct 1 MSVLVISGTSTDVGKTVVTAALAAALRAAGQSVAVCKPAQTGVTVDEPGDLAEVTRLSGV 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
T LARYP+P+AP AA A + + + ++V DLD +TLVEGAGGLLV L
Sbjct 61 TATVELARYPEPLAPDTAARRAALPMLTQTEVVAATRDLDARHDVTLVEGAGGLLVRLGV 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G T+RDVA ++ A +VV A LGTLNH LT EALAA V C+G V+GSWP P L A
Sbjct 121 DGFTVRDVAAELGAPVVVVAAAGLGTLNHCALTAEALAAAGVKCSGFVVGSWPRRPDLAA 180
Query 180 ASNRSALARI--AMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
N L + + V +P G A DA FAA + F+ +W+ L+
Sbjct 181 RCNLHDLPAVTGSAVVGRVPEGVAGSDAAGFAATAPTWFEPDWLDSLL 228
>gi|312140089|ref|YP_004007425.1| dethiobiotin synthetase biod [Rhodococcus equi 103S]
gi|311889428|emb|CBH48745.1| dethiobiotin synthetase BioD [Rhodococcus equi 103S]
Length=231
Score = 155 bits (393), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 114/228 (50%), Positives = 143/228 (63%), Gaps = 3/228 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTG-TARGDDDLAEVGRLAGV 59
+++LV++GT T VGKTVV AALA+A R AG VAVCKP QTG T DLAEV RL+GV
Sbjct 1 MSVLVISGTSTDVGKTVVTAALAAALRAAGQSVAVCKPAQTGVTVDEPGDLAEVTRLSGV 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
T LARYP+P+AP AA A + + + ++V DLD +TLVEGAGGLLV L
Sbjct 61 TATVELARYPEPLAPDTAARRAALPMLTQPEVVAATRDLDARHDVTLVEGAGGLLVRLGA 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G T+RDVA ++ A +VV A LGTLNH LT EALAA V C+G V+GSWP P L A
Sbjct 121 DGFTVRDVAAELGAPVVVVAAAGLGTLNHCALTAEALAAAGVKCSGFVVGSWPRRPDLAA 180
Query 180 ASNRSALARI--AMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 225
N L + + V +P G A DA FAA + F+ +W+ L+
Sbjct 181 RCNLHDLPAVTGSAVVGRVPEGVAGSDAAGFAATAPTWFEPDWLDSLL 228
>gi|256396824|ref|YP_003118388.1| dithiobiotin synthetase [Catenulispora acidiphila DSM 44928]
gi|256363050|gb|ACU76547.1| dethiobiotin synthase [Catenulispora acidiphila DSM 44928]
Length=242
Score = 155 bits (393), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 111/211 (53%), Positives = 133/211 (64%), Gaps = 3/211 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
++I+VVTGT T VGKTVV AA+A+ A G VAV KP QTG A + DLA V +LAGV
Sbjct 1 MSIVVVTGTNTDVGKTVVTAAVATLAATRGTSVAVVKPAQTGVAPEEPGDLATVRQLAGV 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
T L ARYP P++PAAAA +G+A D VR IADL RL LVEGAGGLLV E
Sbjct 61 TDLHEYARYPDPLSPAAAARRSGIAPLDFDDTVRRIADLAEHRRLVLVEGAGGLLVRNDE 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TL D+A + A L+V +LGTLN LTLEA+AA+ + AG+V+GSWP P L
Sbjct 121 DGSTLADLAHALKAPVLLVAHPNLGTLNIAALTLEAMAARGLDLAGIVLGSWPADPDLAM 180
Query 180 ASNRSALARIAM--VRAALPAGAASLDAGDF 208
SN L I + ALPAGA +D DF
Sbjct 181 RSNIRDLETIGARPLAGALPAGAGRMDPADF 211
>gi|320012146|gb|ADW06996.1| dethiobiotin synthase [Streptomyces flavogriseus ATCC 33331]
Length=229
Score = 147 bits (371), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 110/227 (49%), Positives = 135/227 (60%), Gaps = 13/227 (5%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAG- 58
+TILVVTGTGT +GKT+V AA+ASA R + VAV KP QTG A G+ D AEV RLAG
Sbjct 1 MTILVVTGTGTEIGKTIVTAAVASAYRD--LRVAVLKPAQTGLAPGEPGDAAEVARLAGP 58
Query 59 -VTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVEL 117
VT + L R+P+P+AP AA AG+A +I L L LVEGAGGLLV
Sbjct 59 HVTAVE-LVRFPEPLAPGTAARRAGLAPVRPYEIAEAAQKLRTEHDLVLVEGAGGLLVRF 117
Query 118 AEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGL 177
E G TL D A + A LVV A LGTLN T LT EAL + +SC G+V+GS P P L
Sbjct 118 DEEGATLADAARLMEAPVLVVAPAGLGTLNATALTTEALRTRGLSCPGVVVGSMPADPDL 177
Query 178 VAASNRSAL--ARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVA 222
+ N L + A + +PAGA SL+ DF A + R+W+A
Sbjct 178 ASRCNIDDLPVSAGAPLLGVVPAGAGSLEPADFRARA-----RSWLA 219
>gi|134097574|ref|YP_001103235.1| dithiobiotin synthetase [Saccharopolyspora erythraea NRRL 2338]
gi|291009163|ref|ZP_06567136.1| dithiobiotin synthetase [Saccharopolyspora erythraea NRRL 2338]
gi|158513547|sp|A4F8D5.1|BIOD_SACEN RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|133910197|emb|CAM00310.1| dethiobiotin synthetase [Saccharopolyspora erythraea NRRL 2338]
Length=224
Score = 147 bits (371), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 111/215 (52%), Positives = 132/215 (62%), Gaps = 11/215 (5%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
+++LV+TGTGT VGKTVV AA+A+ A VAV K QTG A G+D D+AEV RLAG
Sbjct 1 MSVLVITGTGTEVGKTVVTAAIAALAPG---RVAVLKAAQTGVAAGEDGDVAEVARLAGP 57
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARD-QIVRLIADLDRPGRLTLVEGAGGLLVELA 118
LARYP+P+APA AA AG A P R Q+ +LDR L LVEGAGGLLV
Sbjct 58 VTAVELARYPEPLAPATAARRAG-APPVRPAQVAEAARELDREHDLVLVEGAGGLLVRYD 116
Query 119 EPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLV 178
+ G TL DVAV ++A LVV LGTLN LT EAL A+ V CAG+V+GSWP P L
Sbjct 117 DGG-TLADVAVALSAPVLVVAHGGLGTLNAAALTAEALRARGVECAGVVVGSWPSAPDLA 175
Query 179 AASNRSALARI--AMVRAALPAGAASLDA--GDFA 209
N L + A + LP GAA+ A GD A
Sbjct 176 CRCNLDDLPEVTGAPLLGVLPEGAAADPAAFGDIA 210
>gi|294811367|ref|ZP_06770010.1| Dethiobiotin synthetase [Streptomyces clavuligerus ATCC 27064]
gi|326439902|ref|ZP_08214636.1| dithiobiotin synthetase [Streptomyces clavuligerus ATCC 27064]
gi|294323966|gb|EFG05609.1| Dethiobiotin synthetase [Streptomyces clavuligerus ATCC 27064]
Length=250
Score = 145 bits (366), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 104/219 (48%), Positives = 129/219 (59%), Gaps = 5/219 (2%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
++++VV+GTGT +GKTVV A L + A+ G VAV KP QTG A G+ DLAEV RL G
Sbjct 1 MSVIVVSGTGTDIGKTVVTAGLVALAQ--GRRVAVVKPAQTGVAEGEPGDLAEVVRLGGP 58
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
L R+P+P+APA AA AG+ P +++ IA L L LVEGAGGLLV
Sbjct 59 AHTLELVRFPEPLAPATAARRAGVPGPGAEEVADRIAALSGAYDLVLVEGAGGLLVRFDA 118
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TL D A +AA LVV +A LGTLN LT EAL A+ V+ G+V+GSWP PGL
Sbjct 119 GGSTLADTARLLAAPVLVVASAGLGTLNSVALTGEALRARGVAQLGVVVGSWPAVPGLAD 178
Query 180 ASNRSALARI--AMVRAALPAGAASLDAGDFAAMSAAAF 216
N L A + A+P GA L DF A +A F
Sbjct 179 RCNLLDLPEAAGAPLLGAVPEGAGRLSPADFRARAADWF 217
>gi|291298002|ref|YP_003509280.1| dethiobiotin synthase [Stackebrandtia nassauensis DSM 44728]
gi|290567222|gb|ADD40187.1| dethiobiotin synthase [Stackebrandtia nassauensis DSM 44728]
Length=219
Score = 143 bits (360), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 97/208 (47%), Positives = 132/208 (64%), Gaps = 7/208 (3%)
Query 4 LVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLA 63
++VTGT TGVGKT+ AALA AR AG VAV KPVQTG DDD A + RLA Q+A
Sbjct 9 VIVTGTDTGVGKTIATAALAVVARAAGKTVAVVKPVQTGD---DDDAATIERLAEPDQVA 65
Query 64 GLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVT 123
LAR+P PM+P AAA H G+ ++V +A LD+ L L+EGAGGLLV + T
Sbjct 66 TLARFPDPMSPYAAARHRGLPQLPLAEVVEFVAALDK--DLILIEGAGGLLVPMGTYSWT 123
Query 124 LRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNR 183
+ ++ + A A+VVV A LG++NHT LTLEAL ++ + + ++IGSWP PG V +N+
Sbjct 124 MAELCQQLNAPAVVVVRAGLGSINHTALTLEALRSRGI-LSSVIIGSWPRVPGPVEQANQ 182
Query 184 SALARIAM-VRAALPAGAASLDAGDFAA 210
L+ ++ + +P GA SL +F A
Sbjct 183 IDLSDMSYGLAGIIPEGAGSLSPEEFRA 210
>gi|256379739|ref|YP_003103399.1| dethiobiotin synthase [Actinosynnema mirum DSM 43827]
gi|255924042|gb|ACU39553.1| dethiobiotin synthase [Actinosynnema mirum DSM 43827]
Length=242
Score = 140 bits (352), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 104/226 (47%), Positives = 131/226 (58%), Gaps = 4/226 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
+++LV+TGTGT VGKTVV AALA+ A G VAV KPVQTG G+ DLAEV R+AG
Sbjct 5 VSVLVITGTGTDVGKTVVVAALAAIAAAEGRRVAVLKPVQTGVLPGEPGDLAEVQRMAGP 64
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
L RYP P++PAAAA +G+ +I +LD L L+EGAGGLLV L +
Sbjct 65 VTTRELRRYPDPLSPAAAARRSGLPTAHPAEIAGAATELDDTHDLVLLEGAGGLLVPLDD 124
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TL D A + A LVV A LGTLN T LT E L + + G+VIG WP+ P L A
Sbjct 125 RGATLADAAWALHAPVLVVAHAALGTLNTTALTAEVLVRRGLESIGVVIGRWPEHPDLAA 184
Query 180 ASNRSALARI--AMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAG 223
SN + L + A + LP GA +L +F ++ A W G
Sbjct 185 RSNLTDLPEVAGAPLLGVLPDGAGALSGSEFLEVARAGLS-PWFGG 229
>gi|271969505|ref|YP_003343701.1| dethiobiotin synthase [Streptosporangium roseum DSM 43021]
gi|270512680|gb|ACZ90958.1| Dethiobiotin synthase [Streptosporangium roseum DSM 43021]
Length=240
Score = 139 bits (351), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 108/212 (51%), Positives = 130/212 (62%), Gaps = 3/212 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTG-TARGDDDLAEVGRLAGV 59
++ILVVTGT TGVGKTVV AA+AS AR+ G VAV KP QTG T DL EV RL+G
Sbjct 1 MSILVVTGTDTGVGKTVVTAAVASLARERGTSVAVVKPAQTGVTGTEPGDLDEVIRLSGA 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
T AR+P P+APAAAA AG+ + Q I +L RL +VEGAGGLLV E
Sbjct 61 TSTFEFARFPDPLAPAAAARAAGLPPVSLAQAAARIGELADSHRLVIVEGAGGLLVRFDE 120
Query 120 PGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVA 179
G TL D+A ++A L+V A LGTLNHT LTLEA+A + + G+VIGSWP PGL
Sbjct 121 EGATLADLARALSAPVLLVTRAALGTLNHTALTLEAMAHRGLEPVGVVIGSWPAEPGLAE 180
Query 180 ASNRSALARIAM--VRAALPAGAASLDAGDFA 209
N + L +A + LP GA L FA
Sbjct 181 RCNVADLEMLAARPLAGVLPEGAGVLGREAFA 212
>gi|326333991|ref|ZP_08200221.1| dethiobiotin synthase [Nocardioidaceae bacterium Broad-1]
gi|325948270|gb|EGD40380.1| dethiobiotin synthase [Nocardioidaceae bacterium Broad-1]
Length=218
Score = 139 bits (351), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 95/195 (49%), Positives = 114/195 (59%), Gaps = 6/195 (3%)
Query 3 ILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQL 62
+++VTGT TGVGKTV A LAS AR G V V KPVQTGT GD D AE+ RL G+ ++
Sbjct 8 VVIVTGTSTGVGKTVATATLASRARTNGEKVTVVKPVQTGTDDGDCDAAEIQRLTGI-EV 66
Query 63 AGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGV 122
L R +P+AP AA AG+ +P I+ L R L LVEGAGGLLV L G
Sbjct 67 HELTRLGEPLAPDTAARRAGVEIPPVAAYAPTISALTRDNDLVLVEGAGGLLVRLDTDGG 126
Query 123 T----LRDVAVDVAAAALVVVT-ADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGL 177
T + V + VVVT A LGTLNHT+LT+ AL A+ GL+IGSWP PGL
Sbjct 127 TLLDLADALLVGGTPTSFVVVTAAGLGTLNHTELTVAALRARGHEPDGLIIGSWPGDPGL 186
Query 178 VAASNRSALARIAMV 192
NR L R+ V
Sbjct 187 AERCNRIDLPRVTGV 201
>gi|255324300|ref|ZP_05365421.1| dethiobiotin synthase [Corynebacterium tuberculostearicum SK141]
gi|311741225|ref|ZP_07715049.1| dethiobiotin synthetase [Corynebacterium pseudogenitalium ATCC
33035]
gi|255298630|gb|EET77926.1| dethiobiotin synthase [Corynebacterium tuberculostearicum SK141]
gi|311303395|gb|EFQ79474.1| dethiobiotin synthetase [Corynebacterium pseudogenitalium ATCC
33035]
Length=219
Score = 139 bits (351), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 90/216 (42%), Positives = 123/216 (57%), Gaps = 8/216 (3%)
Query 3 ILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQL 62
I+ VTGT T VGKTV AALASA +Q G +V KP+QTG G D VG+LAGV ++
Sbjct 2 IIYVTGTNTDVGKTVATAALASAFKQRGREVVYAKPLQTGEPEGKGDAVTVGKLAGV-EV 60
Query 63 AGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGV 122
+ R+P+P+AP +A AGM P ++ IA LD PGR+ LVEGAGGLLV LA+
Sbjct 61 TEMVRFPEPLAPNLSARRAGMDQPGLQELKEWIAALDAPGRVVLVEGAGGLLVRLAD-AY 119
Query 123 TLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASN 182
TL DVA L+V + LG+LN +LT+ + GL+ GS P P L N
Sbjct 120 TL----ADVADRLLIVTSLSLGSLNAAELTVREAQRHGIEVLGLIGGSLPADPDLATRLN 175
Query 183 RSALARIA--MVRAALPAGAASLDAGDFAAMSAAAF 216
+ ++ + +LP G A + +FA ++A +
Sbjct 176 LEEMPQVTGCPLWGSLPEGMARMTPAEFARVAAEVY 211
>gi|25027976|ref|NP_738030.1| dithiobiotin synthetase [Corynebacterium efficiens YS-314]
gi|259506369|ref|ZP_05749271.1| dethiobiotin synthetase (dethiobiotin synthase) [Corynebacterium
efficiens YS-314]
gi|81749466|sp|Q8FPS0.1|BIOD_COREF RecName: Full=ATP-dependent dethiobiotin synthetase BioD; AltName:
Full=DTB synthetase; Short=DTBS; AltName: Full=Dethiobiotin
synthase
gi|23493259|dbj|BAC18230.1| dethiobiotin synthase [Corynebacterium efficiens YS-314]
gi|259166047|gb|EEW50601.1| dethiobiotin synthetase (dethiobiotin synthase) [Corynebacterium
efficiens YS-314]
Length=220
Score = 138 bits (348), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 93/218 (43%), Positives = 123/218 (57%), Gaps = 4/218 (1%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVT 60
++IL ++GTGT VGKT+ AALASA G V KPVQTG G D+ V +L+G+
Sbjct 1 MSILFISGTGTDVGKTIATAALASAFHHRGDRVIPVKPVQTGEPDGRGDIHTVEKLSGIR 60
Query 61 QLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEP 120
+ RYP P+AP AA AG+ + R I DLD P R+ LVEGAGG+LV LA+
Sbjct 61 GVE-FTRYPDPLAPNLAARRAGLPQVTLPDLAREIRDLDAPDRIVLVEGAGGVLVRLAD- 118
Query 121 GVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAA 180
+TL DVA ++ A ++V + LG+LN +L+++A V GL+ GS PGL
Sbjct 119 DLTLLDVAAELDAPLVLVTSLGLGSLNAAELSVQAARTAGVEVLGLIGGSASPDPGLAEQ 178
Query 181 SNRSALARIAMVR--AALPAGAASLDAGDFAAMSAAAF 216
N L RI V LPAGA L DF AM+ +
Sbjct 179 LNHGELTRICRVPLLGVLPAGAGDLLPDDFQAMAQSCL 216
>gi|213965966|ref|ZP_03394156.1| dethiobiotin synthase [Corynebacterium amycolatum SK46]
gi|213951380|gb|EEB62772.1| dethiobiotin synthase [Corynebacterium amycolatum SK46]
Length=229
Score = 138 bits (348), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 98/233 (43%), Positives = 133/233 (58%), Gaps = 13/233 (5%)
Query 1 LTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD-DLAEVGRLAGV 59
++I++VTGTGT +GKT+ AALA+ R+ G +V V KP+QTG D DL V L G+
Sbjct 1 MSIVLVTGTGTDIGKTIGTAALAATLREEGKEVHVVKPIQTGFPGPDGGDLDTVAELTGI 60
Query 60 TQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAE 119
L G RYP+PMAP AAA+ AGM LP+ +I I +D P R+ LVEGAGGLLV L E
Sbjct 61 DNLHGFERYPEPMAPVAAAQRAGMRLPSATEIAEKIKLIDGPNRVVLVEGAGGLLVRLGE 120
Query 120 PGVTLRDVAVDVAAAALVVVTA-DLGTLNHTKLTLEALAAQQVSCAGLVIGSWP---DPP 175
L ++A + + +VVVT LG LN +LT+E + + LV GS P DP
Sbjct 121 -DWALPELAGLLPGSQMVVVTRLGLGCLNEAELTVEVARGRGANVTALVGGSLPADVDP- 178
Query 176 GLVAASNRSALARIAMVR--AALPAGAASLDAGDFAAMSAAAFD--RNWVAGL 224
+ +N L R+ V ++ AGA +L +F A ++ R W AGL
Sbjct 179 --IIETNLEELPRVTGVPLLGSVQAGAGALGRQEFVAKASQWLPGVREWAAGL 229
Lambda K H
0.319 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 287912302678
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40