BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1599 Length=438 Score E Sequences producing significant alignments: (Bits) Value gi|289554627|ref|ZP_06443837.1| histidinol dehydrogenase hisD [M... 858 0.0 gi|254231801|ref|ZP_04925128.1| histidinol dehydrogenase hisD [M... 858 0.0 gi|15841052|ref|NP_336089.1| histidinol dehydrogenase [Mycobacte... 858 0.0 gi|15608737|ref|NP_216115.1| histidinol dehydrogenase [Mycobacte... 857 0.0 gi|148822806|ref|YP_001287560.1| histidinol dehydrogenase [Mycob... 857 0.0 gi|344219419|gb|AEN00050.1| histidinol dehydrogenase [Mycobacter... 856 0.0 gi|340626605|ref|YP_004745057.1| putative histidinol dehydrogena... 855 0.0 gi|298525093|ref|ZP_07012502.1| histidinol dehydrogenase hisD [M... 855 0.0 gi|240167971|ref|ZP_04746630.1| histidinol dehydrogenase [Mycoba... 768 0.0 gi|296164465|ref|ZP_06847037.1| histidinol dehydrogenase [Mycoba... 749 0.0 gi|183982409|ref|YP_001850700.1| histidinol dehydrogenase HisD [... 744 0.0 gi|254820949|ref|ZP_05225950.1| histidinol dehydrogenase [Mycoba... 743 0.0 gi|118617222|ref|YP_905554.1| histidinol dehydrogenase [Mycobact... 739 0.0 gi|342860831|ref|ZP_08717481.1| bifunctional histidinal dehydrog... 736 0.0 gi|254775634|ref|ZP_05217150.1| histidinol dehydrogenase [Mycoba... 721 0.0 gi|118471811|ref|YP_887519.1| histidinol dehydrogenase [Mycobact... 709 0.0 gi|118465943|ref|YP_882370.1| histidinol dehydrogenase [Mycobact... 707 0.0 gi|41407391|ref|NP_960227.1| histidinol dehydrogenase [Mycobacte... 706 0.0 gi|336457879|gb|EGO36872.1| histidinol dehydrogenase [Mycobacter... 705 0.0 gi|15827643|ref|NP_301906.1| histidinol dehydrogenase [Mycobacte... 703 0.0 gi|4883452|emb|CAB43166.1| putative histidinol dehydrogenase [My... 688 0.0 gi|333990787|ref|YP_004523401.1| histidinol dehydrogenase [Mycob... 684 0.0 gi|315444531|ref|YP_004077410.1| histidinol dehydrogenase [Mycob... 684 0.0 gi|145224197|ref|YP_001134875.1| histidinol dehydrogenase [Mycob... 682 0.0 gi|108800029|ref|YP_640226.1| histidinol dehydrogenase [Mycobact... 681 0.0 gi|126435658|ref|YP_001071349.1| histidinol dehydrogenase [Mycob... 680 0.0 gi|169629755|ref|YP_001703404.1| histidinol dehydrogenase [Mycob... 678 0.0 gi|312140049|ref|YP_004007385.1| histidinol dehydrogenase hisd [... 670 0.0 gi|120403788|ref|YP_953617.1| histidinol dehydrogenase [Mycobact... 669 0.0 gi|289750144|ref|ZP_06509522.1| histidinol dehydrogenase [Mycoba... 667 0.0 gi|226360171|ref|YP_002777949.1| histidinol dehydrogenase [Rhodo... 665 0.0 gi|229491063|ref|ZP_04384894.1| histidinol dehydrogenase [Rhodoc... 664 0.0 gi|226306939|ref|YP_002766899.1| histidinol dehydrogenase [Rhodo... 663 0.0 gi|111018044|ref|YP_701016.1| histidinol dehydrogenase [Rhodococ... 660 0.0 gi|333919109|ref|YP_004492690.1| Histidinol dehydrogenase [Amyco... 630 1e-178 gi|54023813|ref|YP_118055.1| histidinol dehydrogenase [Nocardia ... 621 9e-176 gi|296139731|ref|YP_003646974.1| histidinol dehydrogenase [Tsuka... 602 3e-170 gi|343926603|ref|ZP_08766102.1| histidinol dehydrogenase [Gordon... 588 7e-166 gi|319950574|ref|ZP_08024483.1| bifunctional histidinal dehydrog... 587 1e-165 gi|302525409|ref|ZP_07277751.1| histidinol dehydrogenase [Strept... 584 8e-165 gi|257055138|ref|YP_003132970.1| histidinol dehydrogenase [Sacch... 582 4e-164 gi|300784161|ref|YP_003764452.1| histidinol dehydrogenase [Amyco... 578 5e-163 gi|262202853|ref|YP_003274061.1| histidinol dehydrogenase [Gordo... 577 2e-162 gi|134102227|ref|YP_001107888.1| histidinol dehydrogenase [Sacch... 568 7e-160 gi|326382622|ref|ZP_08204313.1| bifunctional histidinal dehydrog... 561 9e-158 gi|256379723|ref|YP_003103383.1| histidinol dehydrogenase [Actin... 549 4e-154 gi|38234141|ref|NP_939908.1| histidinol dehydrogenase [Corynebac... 548 9e-154 gi|269127110|ref|YP_003300480.1| histidinol dehydrogenase [Therm... 546 3e-153 gi|213965263|ref|ZP_03393460.1| histidinol dehydrogenase [Coryne... 545 4e-153 gi|72161554|ref|YP_289211.1| histidinol dehydrogenase [Thermobif... 543 2e-152 >gi|289554627|ref|ZP_06443837.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis KZN 605] gi|289745964|ref|ZP_06505342.1| histidinol dehydrogenase [Mycobacterium tuberculosis 02_1987] gi|289439259|gb|EFD21752.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis KZN 605] gi|289686492|gb|EFD53980.1| histidinol dehydrogenase [Mycobacterium tuberculosis 02_1987] gi|328459113|gb|AEB04536.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis KZN 4207] gi|339294555|gb|AEJ46666.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis CCDC5079] gi|339298191|gb|AEJ50301.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis CCDC5180] Length=444 Score = 858 bits (2217), Expect = 0.0, Method: Compositional matrix adjust. Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 7 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 66 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 67 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 126 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 127 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 186 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 187 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 246 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 247 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 306 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 307 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 366 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 367 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 426 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 427 TAEDLPAHGEAVRRRFER 444 >gi|254231801|ref|ZP_04925128.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis C] gi|124600860|gb|EAY59870.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis C] Length=477 Score = 858 bits (2217), Expect = 0.0, Method: Compositional matrix adjust. Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 40 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 99 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 100 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 159 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 160 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 219 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 220 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 279 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 280 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 339 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 340 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 399 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 400 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 459 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 460 TAEDLPAHGEAVRRRFER 477 >gi|15841052|ref|NP_336089.1| histidinol dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|167970638|ref|ZP_02552915.1| histidinol dehydrogenase [Mycobacterium tuberculosis H37Ra] gi|253799363|ref|YP_003032364.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis KZN 1435] 9 more sequence titles Length=447 Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 10 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 69 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 70 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 129 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 130 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 189 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 190 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 249 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 250 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 309 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 310 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 369 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 370 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 429 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 430 TAEDLPAHGEAVRRRFER 447 >gi|15608737|ref|NP_216115.1| histidinol dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|31792785|ref|NP_855278.1| histidinol dehydrogenase [Mycobacterium bovis AF2122/97] gi|121637506|ref|YP_977729.1| histidinol dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] 52 more sequence titles Length=438 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/438 (99%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 1 MLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 421 TAEDLPAHGEAVRRRFER 438 >gi|148822806|ref|YP_001287560.1| histidinol dehydrogenase [Mycobacterium tuberculosis F11] gi|148721333|gb|ABR05958.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis F11] Length=444 Score = 857 bits (2213), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 7 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 66 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDA LAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 67 RPHAIRVPDAALDAVLAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 126 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 127 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 186 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 187 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 246 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 247 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 306 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 307 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 366 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 367 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 426 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 427 TAEDLPAHGEAVRRRFER 444 >gi|344219419|gb|AEN00050.1| histidinol dehydrogenase [Mycobacterium tuberculosis CTRI-2] Length=438 Score = 856 bits (2211), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 1 MLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADH ADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 241 AGPTEIAILADHIADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 421 TAEDLPAHGEAVRRRFER 438 >gi|340626605|ref|YP_004745057.1| putative histidinol dehydrogenase HisD (HDH) [Mycobacterium canettii CIPT 140010059] gi|340004795|emb|CCC43939.1| putative histidinol dehydrogenase HisD (HDH) [Mycobacterium canettii CIPT 140010059] Length=438 Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 1 MLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDG+PHPTILAAARL Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGLPHPTILAAARL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 421 TAEDLPAHGEAVRRRFER 438 >gi|298525093|ref|ZP_07012502.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis 94_M4241A] gi|298494887|gb|EFI30181.1| histidinol dehydrogenase hisD [Mycobacterium tuberculosis 94_M4241A] Length=438 Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV Sbjct 1 MLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW Sbjct 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPA+AAGVDSLVVASPPQAQWDGMPHPTILAAARL Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPARAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV Sbjct 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA Sbjct 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFER 438 TAEDLPAHGEAVRRRFER Sbjct 421 TAEDLPAHGEAVRRRFER 438 >gi|240167971|ref|ZP_04746630.1| histidinol dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=447 Score = 768 bits (1984), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/437 (89%), Positives = 409/437 (94%), Gaps = 0/437 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 L RIDLRGAELTAA LRAALPRGGAD+EAVLP VRPIV AVAERGAEAALDFG SFDGVR Sbjct 11 LARIDLRGAELTAARLRAALPRGGADIEAVLPKVRPIVQAVAERGAEAALDFGESFDGVR 70 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P A+RVPD+ALD+AL L +V EALQVM+ERTRAVH+ QRR+DVTTTLGPGATVTERWV Sbjct 71 PAAVRVPDSALDSALTELASEVREALQVMIERTRAVHADQRRSDVTTTLGPGATVTERWV 130 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PV+RVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLVVASPPQ + G+PHPTILAAARLL Sbjct 131 PVQRVGLYVPGGNAVYPSSVVMNVVPAQVAGVDSLVVASPPQTSFGGLPHPTILAAARLL 190 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GVDEVWAVGGAQAVALLAYGGTDTDGA L PVDMITGPGNIYVTAAKRLCRS VGIDAEA Sbjct 191 GVDEVWAVGGAQAVALLAYGGTDTDGAELVPVDMITGPGNIYVTAAKRLCRSHVGIDAEA 250 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILADHTADP HVAADLISQAEHDE+AASVLVTPS DLADAT+AE+A QLQTT+H Sbjct 251 GPTEIAILADHTADPAHVAADLISQAEHDEMAASVLVTPSPDLADATEAEVAAQLQTTLH 310 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 R RVTAAL+G QSAI+LVDDV+A + VVNAYAAEHLEIQTADAPQVA RIRSAGAIFVGP Sbjct 311 RGRVTAALSGSQSAIILVDDVEAGIKVVNAYAAEHLEIQTADAPQVAGRIRSAGAIFVGP 370 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 W+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+YTEAALKDVSGHVITLA Sbjct 371 WAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYTEAALKDVSGHVITLAK 430 Query 422 AEDLPAHGEAVRRRFER 438 AEDLPAHGEAVRRRFER Sbjct 431 AEDLPAHGEAVRRRFER 447 >gi|296164465|ref|ZP_06847037.1| histidinol dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900163|gb|EFG79597.1| histidinol dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=448 Score = 749 bits (1934), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/438 (87%), Positives = 404/438 (93%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 V+ RIDLRG ELTAA LR ALPRGGADVE+VLP VRPIV AVAERGAEAAL+FG SFDGV Sbjct 11 VMARIDLRGVELTAARLRTALPRGGADVESVLPKVRPIVQAVAERGAEAALEFGESFDGV 70 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP A+RVP+AALD ALA LD D+ EAL+VM+ER RAVH+ QRRTDVTTTLGPGATVTERW Sbjct 71 RPAAVRVPEAALDKALADLDPDIVEALRVMIERARAVHADQRRTDVTTTLGPGATVTERW 130 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVVASPPQA++DG+PHPTILAAARL Sbjct 131 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQARFDGLPHPTILAAARL 190 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTDTDG L VDMITGPGNIYVTAAKRLCRSRVGIDAE Sbjct 191 LGVDEVWAVGGAQAVALLAYGGTDTDGQDLVSVDMITGPGNIYVTAAKRLCRSRVGIDAE 250 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADH+ADP HVAADLISQAEHDE+A SVLVTPS +LA ATD E+A QL+TTV Sbjct 251 AGPTEIAILADHSADPAHVAADLISQAEHDEMAGSVLVTPSAELAAATDTEVAAQLRTTV 310 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HR+RV AAL GRQSAI+LVDD+DA V VVNAYAAEHLEIQT DAP+VA RIRSAGAIFVG Sbjct 311 HRDRVAAALGGRQSAIILVDDLDAGVKVVNAYAAEHLEIQTVDAPEVAGRIRSAGAIFVG 370 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P++PVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YTEAALKDVSGHV+TLA Sbjct 371 PYAPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVVDYTEAALKDVSGHVVTLA 430 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHGEA+RRRFER Sbjct 431 KAEDLPAHGEAIRRRFER 448 >gi|183982409|ref|YP_001850700.1| histidinol dehydrogenase HisD [Mycobacterium marinum M] gi|183175735|gb|ACC40845.1| histidinol dehydrogenase HisD [Mycobacterium marinum M] Length=447 Score = 744 bits (1920), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/438 (89%), Positives = 405/438 (93%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R+DLRGAELTAA LRAALPRGGADVEAVLP VRPIVAAVAERGA+AAL+F SFDGV Sbjct 10 LLARVDLRGAELTAAGLRAALPRGGADVEAVLPKVRPIVAAVAERGAQAALEFCESFDGV 69 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP A+RVP AAL AAL L DV +ALQVM+ERTRAVH+ QRRTDV TTLGPGATVTERW Sbjct 70 RPAAVRVPQAALAAALDELSPDVRDALQVMIERTRAVHADQRRTDVVTTLGPGATVTERW 129 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA G+PHPTILAAARL Sbjct 130 IPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQASHGGLPHPTILAAARL 189 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGGTD DG L PVDMITGPGNIYVTAAKRLCRS+VGIDAE Sbjct 190 LGVDEVWAVGGAQAVALLAYGGTDVDGHELAPVDMITGPGNIYVTAAKRLCRSQVGIDAE 249 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADP HVAADLISQAEHDE+AASVLVTPSE LADATDAELA QL TTV Sbjct 250 AGPTEIAILADHTADPAHVAADLISQAEHDEMAASVLVTPSEHLADATDAELAAQLATTV 309 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERVT AL GRQSAI+LVDD+DA V VVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 310 HHERVTTALGGRQSAIILVDDLDAGVKVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 369 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YTEAALKDVSGHV+TLA Sbjct 370 PWAPVSLGDYCAGSNHVLPTAGFARHSSGLSVQTFLRGIHVVDYTEAALKDVSGHVLTLA 429 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHGEAVRRRFER Sbjct 430 KAEDLPAHGEAVRRRFER 447 >gi|254820949|ref|ZP_05225950.1| histidinol dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=467 Score = 743 bits (1917), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/456 (85%), Positives = 405/456 (89%), Gaps = 19/456 (4%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRGAELTAA LRAALPRGGADVEAVLP VRPIV AVAERGAEAAL+FG SFDGVR Sbjct 12 MARIDLRGAELTAARLRAALPRGGADVEAVLPKVRPIVQAVAERGAEAALEFGESFDGVR 71 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P A+RVP AL+ ALA LD V EAL+VM+ERTRAVH+ QRRTDVTTTLGPGATVTERWV Sbjct 72 PPAVRVPAEALEKALAELDAAVAEALRVMIERTRAVHADQRRTDVTTTLGPGATVTERWV 131 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+ G+PHPTILAAARLL Sbjct 132 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFGGLPHPTILAAARLL 191 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDG-------------------AALTPVDMITGPGNI 222 GVDEVWA+GGAQAVALLAYGGTDT A L PVDMITGPGNI Sbjct 192 GVDEVWAIGGAQAVALLAYGGTDTGAEWPGFSSDRARSASSPGADAELAPVDMITGPGNI 251 Query 223 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSE 282 YVTAAKRLCRSRVGIDAEAGPTEIAILAD+TADP HVAAD+ISQAEHDE+A SVLVTPSE Sbjct 252 YVTAAKRLCRSRVGIDAEAGPTEIAILADNTADPAHVAADMISQAEHDEMAGSVLVTPSE 311 Query 283 DLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTA 342 DLA ATD ELA QL+TTVHRERVTAAL GRQSAI+LVDDVDA V VVNAYAAEHLEIQTA Sbjct 312 DLAAATDKELAAQLRTTVHRERVTAALGGRQSAIILVDDVDAGVKVVNAYAAEHLEIQTA 371 Query 343 DAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV 402 DA VA RIR+AGAIFVGP++PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV Sbjct 372 DAASVAGRIRAAGAIFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV 431 Query 403 EYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 +YTEAALKDVSGHVITLA AEDLPAHGEAVRRRFER Sbjct 432 DYTEAALKDVSGHVITLAEAEDLPAHGEAVRRRFER 467 >gi|118617222|ref|YP_905554.1| histidinol dehydrogenase [Mycobacterium ulcerans Agy99] gi|118569332|gb|ABL04083.1| histidinol dehydrogenase HisD [Mycobacterium ulcerans Agy99] Length=447 Score = 739 bits (1907), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/438 (89%), Positives = 401/438 (92%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R+DLRGAELTAA LRAALPRGGADVEAVLP VRPIVAAVAERGA AAL+F SFDGV Sbjct 10 LLARVDLRGAELTAAGLRAALPRGGADVEAVLPKVRPIVAAVAERGARAALEFCESFDGV 69 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP A+RVP AAL AAL L DV +ALQVM+ERTRAVH QRRTDV TTLGPGATVTERW Sbjct 70 RPAAVRVPQAALAAALDELSPDVRDALQVMIERTRAVHGDQRRTDVVTTLGPGATVTERW 129 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA G+PHPTILAAARL Sbjct 130 IPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQASHGGLPHPTILAAARL 189 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQ VALLAYGGTD DG L PVDMITGPGNIYVTAAKRLCRS+VGIDAE Sbjct 190 LGVDEVWAVGGAQVVALLAYGGTDVDGHELAPVDMITGPGNIYVTAAKRLCRSQVGIDAE 249 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADP HVAADLISQAEHDE+AASVLVTPSE LADATDAELA QL TTV Sbjct 250 AGPTEIAILADHTADPAHVAADLISQAEHDEMAASVLVTPSEHLADATDAELAAQLATTV 309 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERVT AL GRQSAI+LVDD+DA V VVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG Sbjct 310 HHERVTTALGGRQSAIILVDDLDAGVKVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 369 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YTE ALKDVSGHV+TLA Sbjct 370 PWAPVSLGDYCAGSNHVLPTAGFARHSSGLSVQTFLRGIHVVDYTEVALKDVSGHVLTLA 429 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHGEAVRRRFER Sbjct 430 KAEDLPAHGEAVRRRFER 447 >gi|342860831|ref|ZP_08717481.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342131855|gb|EGT85112.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Mycobacterium colombiense CECT 3035] Length=448 Score = 736 bits (1900), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/437 (89%), Positives = 406/437 (93%), Gaps = 0/437 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRGAELTAA LRAALPRGGADVEAVLP VRPIVAAVAERGAEAAL+FGA+FDGVR Sbjct 12 MARIDLRGAELTAARLRAALPRGGADVEAVLPKVRPIVAAVAERGAEAALEFGATFDGVR 71 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P A+RVP AAL+ ALA LD V +AL+VM++RTRAVH+ QRRTDVTTTLGPGATVTERWV Sbjct 72 PPAVRVPHAALEKALADLDARVADALRVMIDRTRAVHADQRRTDVTTTLGPGATVTERWV 131 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PV+RVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+DG+PHPTILAAARLL Sbjct 132 PVDRVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFDGLPHPTILAAARLL 191 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GVDEVWAVGGAQAVALLAYGGTD DGA L PVDMITGPGNIYVTAAKRLCRS VGIDAEA Sbjct 192 GVDEVWAVGGAQAVALLAYGGTDLDGAELAPVDMITGPGNIYVTAAKRLCRSHVGIDAEA 251 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILADHTADP HVAADLISQAEHDE+A SVLVTPS DLA AT+AELA QLQTTVH Sbjct 252 GPTEIAILADHTADPAHVAADLISQAEHDEMAGSVLVTPSADLAAATEAELAAQLQTTVH 311 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 RERVTAAL GRQSAI+LVDD+DA V VVNAYAAEHLEIQT DA VA RIRSAGAIFVGP Sbjct 312 RERVTAALGGRQSAIILVDDLDAGVDVVNAYAAEHLEIQTVDAAAVAGRIRSAGAIFVGP 371 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 ++PVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YTEAALKDVSGHVI LA Sbjct 372 YAPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVVDYTEAALKDVSGHVIALAE 431 Query 422 AEDLPAHGEAVRRRFER 438 AEDLP+HGEAVRRRFER Sbjct 432 AEDLPSHGEAVRRRFER 448 >gi|254775634|ref|ZP_05217150.1| histidinol dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length=456 Score = 721 bits (1860), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/456 (84%), Positives = 405/456 (89%), Gaps = 19/456 (4%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRGAELTAA LR+ALPRGGADVE VLP VRPIV AVAERGA+AAL+FGASFDGVR Sbjct 1 MARIDLRGAELTAARLRSALPRGGADVETVLPKVRPIVQAVAERGADAALEFGASFDGVR 60 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P A+RVP+AALD ALA LD V +AL+VM++R RAVH+ QRRTDVTTTLGPGATVTERWV Sbjct 61 PAAVRVPEAALDKALADLDAAVADALRVMIDRARAVHADQRRTDVTTTLGPGATVTERWV 120 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+DG+PHPTILAAARLL Sbjct 121 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFDGLPHPTILAAARLL 180 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDG-------------------AALTPVDMITGPGNI 222 GVDEVWAVGGAQAVALLAYGGTDT A L PVDMITGPGNI Sbjct 181 GVDEVWAVGGAQAVALLAYGGTDTGAEWPGFSSDRARSASSPGADAELVPVDMITGPGNI 240 Query 223 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSE 282 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADP HVAADLISQAEHDE+A SVLVTPSE Sbjct 241 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPAHVAADLISQAEHDEMAGSVLVTPSE 300 Query 283 DLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTA 342 +LA ATDAELA QL TTVHRERVTAAL G QSAI+LVDD+DA + VVNAYAAEHLEIQTA Sbjct 301 ELATATDAELAAQLPTTVHRERVTAALGGHQSAIILVDDLDAGIAVVNAYAAEHLEIQTA 360 Query 343 DAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV 402 DA VA RIR+AGA+FVGP+SPVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV Sbjct 361 DAAAVAGRIRAAGAVFVGPYSPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVV 420 Query 403 EYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 +YTEAALKDVSGHVITLA AEDLPAHGEA+RRRFER Sbjct 421 DYTEAALKDVSGHVITLAQAEDLPAHGEAIRRRFER 456 >gi|118471811|ref|YP_887519.1| histidinol dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|123180|sp|P28736.1|HISX_MYCSM RecName: Full=Histidinol dehydrogenase; Short=HDH gi|44516|emb|CAA46509.1| histidinol dehydrogenase [Mycobacterium smegmatis] gi|118173098|gb|ABK73994.1| histidinol dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=445 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/437 (84%), Positives = 390/437 (90%), Gaps = 0/437 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 ++RIDLR L+AA+LR+ALPRGG DV+AV+P VRPIV AVA+RGA+AAL++G SFDG+R Sbjct 9 MSRIDLRNRVLSAAQLRSALPRGGVDVDAVVPKVRPIVDAVAQRGAQAALEYGESFDGIR 68 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P +RVP L AL LD DV ALQV ++R RAVH+ QRRTD TTTL PGATVTERWV Sbjct 69 PETVRVPRELLSQALENLDADVRAALQVSIDRARAVHADQRRTDTTTTLAPGATVTERWV 128 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDS+V+ASPPQ Q+ G PHPTILAAA LL Sbjct 129 PVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSMVIASPPQGQFGGRPHPTILAAAALL 188 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GVDEVWAVGGAQAVALLAYGGTDTDGA L PVDMITGPGNIYVTAAKR+CRS+VGIDAEA Sbjct 189 GVDEVWAVGGAQAVALLAYGGTDTDGAELAPVDMITGPGNIYVTAAKRICRSQVGIDAEA 248 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILADHTADPVHVAADLISQAEHDE+AASVLVT SE LA+ATD ELA QL TT H Sbjct 249 GPTEIAILADHTADPVHVAADLISQAEHDEMAASVLVTDSETLAEATDRELANQLATTKH 308 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 ERVTAAL+G+QSAIVLVDD+DA V VNAYAAEHLEIQT DAP VA RIRSAGAIFVG Sbjct 309 VERVTAALSGKQSAIVLVDDIDAGVRTVNAYAAEHLEIQTVDAPGVAGRIRSAGAIFVGA 368 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEY EAALKDVSGHVITL+ Sbjct 369 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYDEAALKDVSGHVITLSK 428 Query 422 AEDLPAHGEAVRRRFER 438 AEDLPAHGEAVRRRFER Sbjct 429 AEDLPAHGEAVRRRFER 445 >gi|118465943|ref|YP_882370.1| histidinol dehydrogenase [Mycobacterium avium 104] gi|118167230|gb|ABK68127.1| histidinol dehydrogenase [Mycobacterium avium 104] Length=467 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/456 (84%), Positives = 406/456 (90%), Gaps = 19/456 (4%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRGAELTAA LR+ALPRGGADVE VLP VRPIV AVAERGA+AAL+FGASFDGVR Sbjct 12 MARIDLRGAELTAARLRSALPRGGADVETVLPKVRPIVQAVAERGADAALEFGASFDGVR 71 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P A+RVP+AALD ALA LD V +AL+VM++R RAVH+ QRRTDVTTTLGPGATVTERWV Sbjct 72 PAAVRVPEAALDKALADLDAAVADALRVMIDRARAVHADQRRTDVTTTLGPGATVTERWV 131 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+DG+PHPTILAAARLL Sbjct 132 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFDGLPHPTILAAARLL 191 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDG-------------------AALTPVDMITGPGNI 222 GVDEVWAVGGAQAVALLAYGGTDT A L PVDMITGPGNI Sbjct 192 GVDEVWAVGGAQAVALLAYGGTDTGAEWPGFSSDRARSASSPGADAELVPVDMITGPGNI 251 Query 223 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSE 282 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADP HVAADLISQAEHDE+A SVLVTPSE Sbjct 252 YVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPAHVAADLISQAEHDEMAGSVLVTPSE 311 Query 283 DLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTA 342 +LA ATDAELA QL TTVHRERVTAAL GRQSAI+LVDD+DA + VVNAYAAEHLEIQTA Sbjct 312 ELAAATDAELAAQLPTTVHRERVTAALGGRQSAIILVDDLDAGITVVNAYAAEHLEIQTA 371 Query 343 DAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV 402 DA VA RIR+AGA+FVGP+SPVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV Sbjct 372 DAAAVAGRIRAAGAVFVGPYSPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVV 431 Query 403 EYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 +YTEAALKDVSGHVITLA AEDLPAHGEA+RRRFER Sbjct 432 DYTEAALKDVSGHVITLAQAEDLPAHGEAIRRRFER 467 >gi|41407391|ref|NP_960227.1| histidinol dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|46395653|sp|P60860.1|HISX_MYCPA RecName: Full=Histidinol dehydrogenase; Short=HDH gi|41395743|gb|AAS03610.1| HisD [Mycobacterium avium subsp. paratuberculosis K-10] Length=480 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/453 (85%), Positives = 404/453 (90%), Gaps = 19/453 (4%) Query 5 IDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHA 64 IDLRGAELTAA LR+ALPRGGADVE VLP VRPIV AVAERGA+AAL+FGASFDGVRP A Sbjct 28 IDLRGAELTAARLRSALPRGGADVETVLPKVRPIVQAVAERGADAALEFGASFDGVRPAA 87 Query 65 IRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVE 124 +RVP+AALD ALA LD V +AL+VM++R RAVH+ QRRTDVTTTLGPGATVTERWVPVE Sbjct 88 VRVPEAALDKALADLDAAVADALRVMIDRARAVHADQRRTDVTTTLGPGATVTERWVPVE 147 Query 125 RVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLLGVD 184 RVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+DG+PHPTILAAARLLGVD Sbjct 148 RVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFDGLPHPTILAAARLLGVD 207 Query 185 EVWAVGGAQAVALLAYGGTDTDG-------------------AALTPVDMITGPGNIYVT 225 EVWAVGGAQAVALLAYGGTDT A L PVDMITGPGNIYVT Sbjct 208 EVWAVGGAQAVALLAYGGTDTGAEWPGFSSDRARSASSPGADAELVPVDMITGPGNIYVT 267 Query 226 AAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLA 285 AAKRLCRSRVGIDAEAGPTEIAILADHTADP HVAADLISQAEHDE+A SVLVTPSEDLA Sbjct 268 AAKRLCRSRVGIDAEAGPTEIAILADHTADPAHVAADLISQAEHDEMAGSVLVTPSEDLA 327 Query 286 DATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAP 345 ATDAELA QL TTVHRERVTAAL GRQSAI+LVDD+DA + VVNAYAAEHLEIQTADA Sbjct 328 AATDAELAAQLPTTVHRERVTAALGGRQSAIILVDDLDAGITVVNAYAAEHLEIQTADAA 387 Query 346 QVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYT 405 VA RIR+AGA+FVGP+SPVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YT Sbjct 388 AVAGRIRAAGAVFVGPYSPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVVDYT 447 Query 406 EAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 EAALKDVSGHVITLA AEDLPAHGEA+RRRFER Sbjct 448 EAALKDVSGHVITLAQAEDLPAHGEAIRRRFER 480 >gi|336457879|gb|EGO36872.1| histidinol dehydrogenase [Mycobacterium avium subsp. paratuberculosis S397] Length=467 Score = 705 bits (1820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/453 (85%), Positives = 404/453 (90%), Gaps = 19/453 (4%) Query 5 IDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHA 64 IDLRGAELTAA LR+ALPRGGADVE VLP VRPIV AVAERGA+AAL+FGASFDGVRP A Sbjct 15 IDLRGAELTAARLRSALPRGGADVETVLPKVRPIVQAVAERGADAALEFGASFDGVRPAA 74 Query 65 IRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVE 124 +RVP+AALD ALA LD V +AL+VM++R RAVH+ QRRTDVTTTLGPGATVTERWVPVE Sbjct 75 VRVPEAALDKALADLDAAVADALRVMIDRARAVHADQRRTDVTTTLGPGATVTERWVPVE 134 Query 125 RVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLLGVD 184 RVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQAQ+DG+PHPTILAAARLLGVD Sbjct 135 RVGLYVPGGNAVYPSSVVMNVVPAQAAGVASLVVASPPQAQFDGLPHPTILAAARLLGVD 194 Query 185 EVWAVGGAQAVALLAYGGTDTDG-------------------AALTPVDMITGPGNIYVT 225 EVWAVGGAQAVALLAYGGTDT A L PVDMITGPGNIYVT Sbjct 195 EVWAVGGAQAVALLAYGGTDTGAEWPGFSSDRARSASSPGADAELVPVDMITGPGNIYVT 254 Query 226 AAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLA 285 AAKRLCRSRVGIDAEAGPTEIAILADHTADP HVAADLISQAEHDE+A SVLVTPSEDLA Sbjct 255 AAKRLCRSRVGIDAEAGPTEIAILADHTADPAHVAADLISQAEHDEMAGSVLVTPSEDLA 314 Query 286 DATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAP 345 ATDAELA QL TTVHRERVTAAL GRQSAI+LVDD+DA + VVNAYAAEHLEIQTADA Sbjct 315 AATDAELAAQLPTTVHRERVTAALGGRQSAIILVDDLDAGITVVNAYAAEHLEIQTADAA 374 Query 346 QVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYT 405 VA RIR+AGA+FVGP+SPVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRGIHVV+YT Sbjct 375 AVAGRIRAAGAVFVGPYSPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGIHVVDYT 434 Query 406 EAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 EAALKDVSGHVITLA AEDLPAHGEA+RRRFER Sbjct 435 EAALKDVSGHVITLAQAEDLPAHGEAIRRRFER 467 >gi|15827643|ref|NP_301906.1| histidinol dehydrogenase [Mycobacterium leprae TN] gi|221230120|ref|YP_002503536.1| histidinol dehydrogenase [Mycobacterium leprae Br4923] gi|15214042|sp|Q9CC57.1|HISX_MYCLE RecName: Full=Histidinol dehydrogenase; Short=HDH gi|13093194|emb|CAC31638.1| histidinol dehydrogenase [Mycobacterium leprae] gi|219933227|emb|CAR71352.1| histidinol dehydrogenase [Mycobacterium leprae Br4923] Length=449 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/442 (85%), Positives = 399/442 (91%), Gaps = 4/442 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L IDLRGAELTA +LRA LPRGGADVEAVLPTV PIV AVAE GA+AAL+FGA FDGV Sbjct 8 LLACIDLRGAELTATQLRATLPRGGADVEAVLPTVWPIVQAVAECGADAALEFGALFDGV 67 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVPDAALDAALAGLD DV +ALQVM+ERTR VH+ QRRTDVTT LGPGATVTERW Sbjct 68 RPPTVRVPDAALDAALAGLDPDVRDALQVMIERTRVVHADQRRTDVTTALGPGATVTERW 127 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQ----AQWDGMPHPTILA 176 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLVVASPPQ ++ G+PHPTILA Sbjct 128 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVVASPPQFTSGGRFHGLPHPTILA 187 Query 177 AARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVG 236 AARLLGVDEVWAVGGAQAVALLAYGGTD+D L PVDMITGPGNIYVTAAKRLCRSRVG Sbjct 188 AARLLGVDEVWAVGGAQAVALLAYGGTDSDDCELAPVDMITGPGNIYVTAAKRLCRSRVG 247 Query 237 IDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQL 296 ID EAGPTEIAILADHTADP HVAAD+ISQAEHDE+AASVLVTPS DLADATDAELA QL Sbjct 248 IDGEAGPTEIAILADHTADPAHVAADMISQAEHDEMAASVLVTPSTDLADATDAELAAQL 307 Query 297 QTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGA 356 +TTVHR+RV AAL GRQSAI+LVDD++A V VVN YAAEHLEIQTA+A +VASRIR AGA Sbjct 308 RTTVHRKRVVAALGGRQSAIILVDDLEAGVKVVNLYAAEHLEIQTAEASRVASRIRCAGA 367 Query 357 IFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHV 416 IFVGPW+PVSLGDYCAGSNHVLPTAG ARHS GLSVQTFLRGIHVV YT+ ALKD+SGHV Sbjct 368 IFVGPWAPVSLGDYCAGSNHVLPTAGFARHSGGLSVQTFLRGIHVVNYTKTALKDISGHV 427 Query 417 ITLATAEDLPAHGEAVRRRFER 438 ITLA AEDLPAHGEAVRRRF R Sbjct 428 ITLAKAEDLPAHGEAVRRRFAR 449 >gi|4883452|emb|CAB43166.1| putative histidinol dehydrogenase [Mycobacterium leprae] Length=431 Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/431 (85%), Positives = 390/431 (91%), Gaps = 4/431 (0%) Query 12 LTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVRPHAIRVPDAA 71 +TA +LRA LPRGGADVEAVLPTV PIV AVAE GA+AAL+FGA FDGVRP +RVPDAA Sbjct 1 MTATQLRATLPRGGADVEAVLPTVWPIVQAVAECGADAALEFGALFDGVRPPTVRVPDAA 60 Query 72 LDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWVPVERVGLYVP 131 LDAALAGLD DV +ALQVM+ERTR VH+ QRRTDVTT LGPGATVTERWVPVERVGLYVP Sbjct 61 LDAALAGLDPDVRDALQVMIERTRVVHADQRRTDVTTALGPGATVTERWVPVERVGLYVP 120 Query 132 GGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQ----AQWDGMPHPTILAAARLLGVDEVW 187 GGNAVYPSSVVMNVVPAQ AGVDSLVVASPPQ ++ G+PHPTILAAARLLGVDEVW Sbjct 121 GGNAVYPSSVVMNVVPAQTAGVDSLVVASPPQFTSGGRFHGLPHPTILAAARLLGVDEVW 180 Query 188 AVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIA 247 AVGGAQAVALLAYGGTD+D L PVDMITGPGNIYVTAAKRLCRSRVGID EAGPTEIA Sbjct 181 AVGGAQAVALLAYGGTDSDDCELAPVDMITGPGNIYVTAAKRLCRSRVGIDGEAGPTEIA 240 Query 248 ILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVHRERVTA 307 ILADHTADP HVAAD+ISQAEHDE+AASVLVTPS DLADATDAELA QL+TTVHR+RV A Sbjct 241 ILADHTADPAHVAADMISQAEHDEMAASVLVTPSTDLADATDAELAAQLRTTVHRKRVVA 300 Query 308 ALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSL 367 AL GRQSAI+LVDD++A V VVN YAAEHLEIQTA+A +VASRIR AGAIFVGPW+PVSL Sbjct 301 ALGGRQSAIILVDDLEAGVKVVNLYAAEHLEIQTAEASRVASRIRCAGAIFVGPWAPVSL 360 Query 368 GDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPA 427 GDYCAGSNHVLPTAG ARHS GLSVQTFLRGIHVV YT+ ALKD+SGHVITLA AEDLPA Sbjct 361 GDYCAGSNHVLPTAGFARHSGGLSVQTFLRGIHVVNYTKTALKDISGHVITLAKAEDLPA 420 Query 428 HGEAVRRRFER 438 HGEAVRRRF R Sbjct 421 HGEAVRRRFAR 431 >gi|333990787|ref|YP_004523401.1| histidinol dehydrogenase [Mycobacterium sp. JDM601] gi|333486755|gb|AEF36147.1| histidinol dehydrogenase HisD [Mycobacterium sp. JDM601] Length=449 Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/442 (82%), Positives = 395/442 (90%), Gaps = 4/442 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +++RIDLRGA L+AA LRAALPRGG DVEAVLP VRPIV AVAERG+ AAL+FG SFDG+ Sbjct 8 LMSRIDLRGANLSAASLRAALPRGGVDVEAVLPQVRPIVEAVAERGSAAALEFGESFDGI 67 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP A+RVP+AAL+AALA LD V AL+V + R RAVH+ QRRTD TT L PGATV+ERW Sbjct 68 RPAAVRVPEAALEAALAELDPAVRAALEVAISRARAVHADQRRTDTTTMLAPGATVSERW 127 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA----QWDGMPHPTILA 176 +PVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQA Q+ G+PHPTILA Sbjct 128 IPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQADLQGQFQGLPHPTILA 187 Query 177 AARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVG 236 AARLLGV EVWAVGGAQAVALLAYGGTDTD A L PVDMITGPGNIYVTAAKRLCRS+VG Sbjct 188 AARLLGVAEVWAVGGAQAVALLAYGGTDTDQAELVPVDMITGPGNIYVTAAKRLCRSQVG 247 Query 237 IDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQL 296 IDAEAGPTEIAILADHTA+P H+AADLISQAEHDELAASVLVT S ADATD E+ QL Sbjct 248 IDAEAGPTEIAILADHTANPAHLAADLISQAEHDELAASVLVTTSPQQADATDREVTAQL 307 Query 297 QTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGA 356 +TTVHR+RV ALTGRQSAIVLVDD+DA + VVNAYAAEHLEIQTADA VA+RIRSAGA Sbjct 308 ETTVHRQRVVTALTGRQSAIVLVDDLDAGIRVVNAYAAEHLEIQTADAAAVAARIRSAGA 367 Query 357 IFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHV 416 IFVGP++PVSLGDYCAGSNHVLPTAG ARHSSGLSVQTFLRG+HVV+YTEAALKDVSGHV Sbjct 368 IFVGPYAPVSLGDYCAGSNHVLPTAGSARHSSGLSVQTFLRGVHVVDYTEAALKDVSGHV 427 Query 417 ITLATAEDLPAHGEAVRRRFER 438 I LA AEDLP+HGEAVRRRFE+ Sbjct 428 IALADAEDLPSHGEAVRRRFEQ 449 >gi|315444531|ref|YP_004077410.1| histidinol dehydrogenase [Mycobacterium sp. Spyr1] gi|315262834|gb|ADT99575.1| histidinol dehydrogenase [Mycobacterium sp. Spyr1] Length=452 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/442 (84%), Positives = 393/442 (89%), Gaps = 5/442 (1%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L RIDLR L+AA LR ALPRGG DV+AV+P VRPIV AVA RGA+AAL++GASFDGV Sbjct 10 LLRRIDLRDTALSAARLRTALPRGGVDVDAVVPKVRPIVDAVAARGADAALEYGASFDGV 69 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP L AL LD DV AL+V +ERTR VH+ QRRTD TTTL PGATVTERW Sbjct 70 RPDRVRVPSNKLTEALDTLDDDVRTALEVAIERTRIVHADQRRTDTTTTLAPGATVTERW 129 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA----QWDGMPHPTILA 176 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQ ++ G+PHPTILA Sbjct 130 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQKTNPDRFAGLPHPTILA 189 Query 177 AARLLGVDEVWAVGGAQAVALLAYGGTDTDGAA-LTPVDMITGPGNIYVTAAKRLCRSRV 235 AA LLGVDEVWAVGGAQAVALLAYGGTDTDG L PVDMITGPGNIYVTAAKR+CRS+V Sbjct 190 AAALLGVDEVWAVGGAQAVALLAYGGTDTDGETELAPVDMITGPGNIYVTAAKRICRSQV 249 Query 236 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQ 295 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDE+AASVLVT S DLADATD ELA Q Sbjct 250 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDEMAASVLVTDSTDLADATDRELALQ 309 Query 296 LQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAG 355 L+TTVHRERVTAAL GRQSAIVLVDDVDA V VNAYAAEHLEIQTADA QVA+RIRSAG Sbjct 310 LETTVHRERVTAALRGRQSAIVLVDDVDAGVRTVNAYAAEHLEIQTADAAQVANRIRSAG 369 Query 356 AIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGH 415 AIFVGP+SPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+YTEAALKDVSG+ Sbjct 370 AIFVGPYSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYTEAALKDVSGY 429 Query 416 VITLATAEDLPAHGEAVRRRFE 437 VITLA AE+LP+HGEAVRRRFE Sbjct 430 VITLANAENLPSHGEAVRRRFE 451 >gi|145224197|ref|YP_001134875.1| histidinol dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|145216683|gb|ABP46087.1| histidinol dehydrogenase [Mycobacterium gilvum PYR-GCK] Length=449 Score = 682 bits (1759), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/442 (84%), Positives = 393/442 (89%), Gaps = 5/442 (1%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L RIDLR L+AA LR ALPRGG DV+AV+P VRPIV AVA RGA+AAL++GASFDGV Sbjct 7 LLRRIDLRDTALSAARLRTALPRGGVDVDAVVPKVRPIVDAVAARGADAALEYGASFDGV 66 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP L AL LD DV AL+V +ERTR VH+ QRRTD TTTL PGATVTERW Sbjct 67 RPDRVRVPSNKLTEALDTLDDDVRTALEVAIERTRIVHADQRRTDTTTTLAPGATVTERW 126 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA----QWDGMPHPTILA 176 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQ ++ G+PHPTILA Sbjct 127 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQKTNPDRFAGLPHPTILA 186 Query 177 AARLLGVDEVWAVGGAQAVALLAYGGTDTDGAA-LTPVDMITGPGNIYVTAAKRLCRSRV 235 AA LLGVDEVWAVGGAQAVALLAYGGTDTDG L PVDMITGPGNIYVTAAKR+CRS+V Sbjct 187 AAALLGVDEVWAVGGAQAVALLAYGGTDTDGETELAPVDMITGPGNIYVTAAKRICRSQV 246 Query 236 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQ 295 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDE+AASVLVT S +LADATD ELA Q Sbjct 247 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDEMAASVLVTDSTELADATDRELALQ 306 Query 296 LQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAG 355 L+TTVHRERVTAAL GRQSAIVLVDDVDA V VNAYAAEHLEIQTADA QVA+RIRSAG Sbjct 307 LETTVHRERVTAALRGRQSAIVLVDDVDAGVRTVNAYAAEHLEIQTADAAQVANRIRSAG 366 Query 356 AIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGH 415 AIFVGP+SPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+YTEAALKDVSG+ Sbjct 367 AIFVGPYSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYTEAALKDVSGY 426 Query 416 VITLATAEDLPAHGEAVRRRFE 437 VITLA AE+LP+HGEAVRRRFE Sbjct 427 VITLANAENLPSHGEAVRRRFE 448 >gi|108800029|ref|YP_640226.1| histidinol dehydrogenase [Mycobacterium sp. MCS] gi|119869154|ref|YP_939106.1| histidinol dehydrogenase [Mycobacterium sp. KMS] gi|108770448|gb|ABG09170.1| histidinol dehydrogenase [Mycobacterium sp. MCS] gi|119695243|gb|ABL92316.1| histidinol dehydrogenase [Mycobacterium sp. KMS] Length=474 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/466 (78%), Positives = 391/466 (84%), Gaps = 30/466 (6%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRG L+ A+LR+ALPRGG DV+AV+P VRPIV AVAERGAEAAL++G +FDGVR Sbjct 8 MARIDLRGRTLSTAQLRSALPRGGVDVDAVVPKVRPIVEAVAERGAEAALEYGEAFDGVR 67 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P ++RVP L +ALA LD DV ALQV ++R RAVH+ QRRTD TTTL PGATVTERWV Sbjct 68 PASVRVPAERLASALAELDPDVRAALQVAIDRARAVHADQRRTDTTTTLAPGATVTERWV 127 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 P+ERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQA G+PHPTILAAA LL Sbjct 128 PLERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQADHGGLPHPTILAAAALL 187 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAA------------------------------LT 211 GVDEVWAVGGAQAVALLAYGGTD DG L Sbjct 188 GVDEVWAVGGAQAVALLAYGGTDIDGTGASGAPGDGTGASGAPGDGTGASGAPGDGTELA 247 Query 212 PVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDE 271 PVDMITGPGNIYVTAAKR+CRS+VGIDAEAGPTEIA+LADHTADPVHVAADLISQAEHDE Sbjct 248 PVDMITGPGNIYVTAAKRICRSQVGIDAEAGPTEIAVLADHTADPVHVAADLISQAEHDE 307 Query 272 LAASVLVTPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNA 331 +AASVLVT S DLADA D EL QL+TTVHRERV+ ALTG QSAIVLVDD+DA V VVNA Sbjct 308 MAASVLVTTSPDLADAIDRELRRQLETTVHRERVSTALTGEQSAIVLVDDLDAGVRVVNA 367 Query 332 YAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLS 391 YAAEHLEIQT DA +VA RIRSAGAIFVGP++PVSLGDYCAGSNHVLPTAGCARHSSGLS Sbjct 368 YAAEHLEIQTVDAAEVAGRIRSAGAIFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLS 427 Query 392 VQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFE 437 VQTFLRGIHVV+YTEAALKDVSG+VITLA AE+LPAHGEAVRRRFE Sbjct 428 VQTFLRGIHVVDYTEAALKDVSGYVITLAQAENLPAHGEAVRRRFE 473 >gi|126435658|ref|YP_001071349.1| histidinol dehydrogenase [Mycobacterium sp. JLS] gi|126235458|gb|ABN98858.1| histidinol dehydrogenase [Mycobacterium sp. JLS] Length=474 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/466 (78%), Positives = 391/466 (84%), Gaps = 30/466 (6%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 + RIDLRG L+ A+LR+ALPRGG DV+AV+P VRPIV AVAERGAEAAL++G +FDGVR Sbjct 8 MARIDLRGRTLSTAQLRSALPRGGVDVDAVVPKVRPIVEAVAERGAEAALEYGEAFDGVR 67 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P ++RVP L +ALA LD DV ALQV ++R RAVH+ QRRTD TTTL PGATVTERWV Sbjct 68 PASVRVPAERLASALAELDPDVRAALQVAIDRARAVHADQRRTDTTTTLAPGATVTERWV 127 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 P+ERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQA G+PHPTILAAA LL Sbjct 128 PLERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQADHGGLPHPTILAAAALL 187 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAA------------------------------LT 211 GVDEVWAVGGAQAVALLAYGGTD DG L Sbjct 188 GVDEVWAVGGAQAVALLAYGGTDIDGTGASGAPGDGTGASGAPGDGTGASGAPGDVTELA 247 Query 212 PVDMITGPGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDE 271 PVDMITGPGNIYVTAAKR+CRS+VGIDAEAGPTEIA+LADHTADPVHVAADLISQAEHDE Sbjct 248 PVDMITGPGNIYVTAAKRICRSQVGIDAEAGPTEIAVLADHTADPVHVAADLISQAEHDE 307 Query 272 LAASVLVTPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNA 331 +AASVLVT S DLADA D EL QL+TTVHRERV+ ALTG QSAIVLVDD+DA V VVNA Sbjct 308 MAASVLVTTSPDLADAIDRELRRQLETTVHRERVSTALTGEQSAIVLVDDLDAGVRVVNA 367 Query 332 YAAEHLEIQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLS 391 YAAEHLEIQT DA +VA RIRSAGAIFVGP++PVSLGDYCAGSNHVLPTAGCARHSSGLS Sbjct 368 YAAEHLEIQTVDAAEVAGRIRSAGAIFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLS 427 Query 392 VQTFLRGIHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFE 437 VQTFLRGIHVV+YTEAALKDVSG+VITLA AE+LPAHGEAVRRRFE Sbjct 428 VQTFLRGIHVVDYTEAALKDVSGYVITLAQAENLPAHGEAVRRRFE 473 >gi|169629755|ref|YP_001703404.1| histidinol dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169241722|emb|CAM62750.1| Histidinol dehydrogenase (HisD) [Mycobacterium abscessus] Length=446 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/438 (80%), Positives = 380/438 (87%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L RID+RGA L+ + LRAALPRGG DV+AVLP VRP+V AV +RGAEAALDF A FDGV Sbjct 8 LLRRIDMRGASLSPSHLRAALPRGGTDVDAVLPRVRPVVEAVRDRGAEAALDFCAEFDGV 67 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP A LD ALA LD V +AL+V + R RAVH+ QRR D TT+ GATVTERW Sbjct 68 RPGTVRVPAAELDRALADLDPAVRDALEVAILRARAVHADQRRQDTVTTVADGATVTERW 127 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLV+ASPPQAQ+ G+PHPTILAAA+L Sbjct 128 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVIASPPQAQFGGLPHPTILAAAQL 187 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGV EVWAVGGAQ VALLA+GGTDTDGA L PVDMITGPGNIYVTAAKRLCRS VGIDAE Sbjct 188 LGVQEVWAVGGAQGVALLAHGGTDTDGAELAPVDMITGPGNIYVTAAKRLCRSLVGIDAE 247 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD TADPVHVAADLISQAEHD LAASVLVT S LADA E + QL TTV Sbjct 248 AGPTEIAILADETADPVHVAADLISQAEHDVLAASVLVTDSAALADAVVKETSAQLATTV 307 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERVTAALTG QS IVLVDD+DA + VVNAYAAEHLEI T + VA+R+R+AGAIF+G Sbjct 308 HAERVTAALTGTQSGIVLVDDIDAGIKVVNAYAAEHLEIHTVEPVPVAARVRNAGAIFLG 367 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIH+V+YTEAALK+V+GHVITLA Sbjct 368 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHIVDYTEAALKEVAGHVITLA 427 Query 421 TAEDLPAHGEAVRRRFER 438 AE+LPAHGEAVRRRFER Sbjct 428 NAENLPAHGEAVRRRFER 445 >gi|312140049|ref|YP_004007385.1| histidinol dehydrogenase hisd [Rhodococcus equi 103S] gi|325674474|ref|ZP_08154162.1| histidinol dehydrogenase [Rhodococcus equi ATCC 33707] gi|311889388|emb|CBH48704.1| histidinol dehydrogenase HisD [Rhodococcus equi 103S] gi|325554734|gb|EGD24408.1| histidinol dehydrogenase [Rhodococcus equi ATCC 33707] Length=440 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/437 (79%), Positives = 373/437 (86%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + AELR ALPRGG DV+AVL VRP+V + +RGAEAAL++G FDGV Sbjct 1 MLARTDLRGRTPSTAELRGALPRGGVDVDAVLHQVRPVVEDIRDRGAEAALEYGEKFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP A LD ALA LD DV AL+V +ERTR VH+ QRRTD T + PG TVTERW Sbjct 61 RPGTVRVPQAELDRALAELDADVRAALEVAIERTRKVHADQRRTDTVTEVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGV+SLVVASPPQA + G+PHPTILAAA L Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVESLVVASPPQAAFGGLPHPTILAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALL YGGTDTD A L PVD+ITGPGNI+VTAAKRLCR VGIDAE Sbjct 181 LGVDEVWAVGGAQAVALLTYGGTDTDSAELAPVDLITGPGNIFVTAAKRLCRGLVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAAD+ISQAEHD +AASVLVT S DLADA D LA QL+ T Sbjct 241 AGPTEIAILADHTADPVHVAADMISQAEHDVMAASVLVTTSTDLADAVDTALAAQLEITK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERV AL G QS VLVDD+ A + VVNAYAAEHLEIQT +A VA+++RSAGAIFVG Sbjct 301 HRERVETALRGSQSGTVLVDDIAAGLKVVNAYAAEHLEIQTENASAVAAQVRSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+Y+EAALKDV+GHVITLA Sbjct 361 PWAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYSEAALKDVAGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAVR RFE Sbjct 421 NAEDLPAHGEAVRLRFE 437 >gi|120403788|ref|YP_953617.1| histidinol dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119956606|gb|ABM13611.1| histidinol dehydrogenase [Mycobacterium vanbaalenii PYR-1] Length=451 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/442 (83%), Positives = 391/442 (89%), Gaps = 4/442 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L RIDLRG L+AA LR+ALPRGG DV+ V+P VRPIV AVAERGA AAL++GA+FDG+ Sbjct 10 LLRRIDLRGTTLSAARLRSALPRGGVDVDTVVPKVRPIVDAVAERGAAAALEYGAAFDGI 69 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP L AALA LD DV AL+V +ER RAVH+ QRRTD TTTL PGATVTERW Sbjct 70 RPDQVRVPAERLKAALAELDPDVRTALEVAIERARAVHADQRRTDTTTTLAPGATVTERW 129 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQA----QWDGMPHPTILA 176 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGVDSLV+ASPPQA + G+PHPTILA Sbjct 130 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQAGNAEPFKGLPHPTILA 189 Query 177 AARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVG 236 AA LLGVDEVWAVGGAQAVALLAYGG DTDGA L PVDMITGPGNIYVTAAKR+CRS VG Sbjct 190 AAALLGVDEVWAVGGAQAVALLAYGGVDTDGAELAPVDMITGPGNIYVTAAKRICRSAVG 249 Query 237 IDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQL 296 IDAEAGPTEIAILADHTADP HV ADLISQAEHDE+AASVLVT S +LADATD ELA QL Sbjct 250 IDAEAGPTEIAILADHTADPAHVVADLISQAEHDEMAASVLVTDSAELADATDRELAVQL 309 Query 297 QTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGA 356 +TTVHRERVTAAL G+QSAIVLVDD++A + VNAYAAEHLEIQT DA VA RIRSAGA Sbjct 310 ETTVHRERVTAALGGQQSAIVLVDDIEAGIRTVNAYAAEHLEIQTVDAAAVAGRIRSAGA 369 Query 357 IFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHV 416 IFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+YTEAALKDVSG+V Sbjct 370 IFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYTEAALKDVSGYV 429 Query 417 ITLATAEDLPAHGEAVRRRFER 438 ITLA AE+LP+HGEAVRRRFER Sbjct 430 ITLAKAENLPSHGEAVRRRFER 451 >gi|289750144|ref|ZP_06509522.1| histidinol dehydrogenase [Mycobacterium tuberculosis T92] gi|289690731|gb|EFD58160.1| histidinol dehydrogenase [Mycobacterium tuberculosis T92] Length=358 Score = 667 bits (1721), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/340 (99%), Positives = 337/340 (99%), Gaps = 0/340 (0%) Query 99 SGQRRTDVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVV 158 S RR DVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVV Sbjct 19 SAHRRVDVTTTLGPGATVTERWVPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVV 78 Query 159 ASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITG 218 ASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITG Sbjct 79 ASPPQAQWDGMPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITG 138 Query 219 PGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLV 278 PGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLV Sbjct 139 PGNIYVTAAKRLCRSRVGIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLV 198 Query 279 TPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLE 338 TPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLE Sbjct 199 TPSEDLADATDAELAGQLQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLE 258 Query 339 IQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRG 398 IQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRG Sbjct 259 IQTADAPQVASRIRSAGAIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRG 318 Query 399 IHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER 438 IHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER Sbjct 319 IHVVEYTEAALKDVSGHVITLATAEDLPAHGEAVRRRFER 358 >gi|226360171|ref|YP_002777949.1| histidinol dehydrogenase [Rhodococcus opacus B4] gi|226238656|dbj|BAH49004.1| histidinol dehydrogenase [Rhodococcus opacus B4] Length=440 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/437 (79%), Positives = 373/437 (86%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + AELRAALPRGG DV+AVL VRP+V AV ERGA+AAL+F FDGV Sbjct 1 MLARTDLRGRTPSTAELRAALPRGGVDVDAVLHQVRPVVEAVRERGADAALEFSEKFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP + LD AL LD V AL+V +ERTR VH+ QRRTD TT + PG TVTERW Sbjct 61 RPAQVRVPQSELDRALHELDPAVRAALEVAIERTRKVHADQRRTDTTTEVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV+RVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQ+ + G+PHPTILAAA L Sbjct 121 VPVDRVGLYVPGGNAVYPSSVVMNVVPAQAAGVRSLVVASPPQSGFGGLPHPTILAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGG QAVALL YGGTDTDGA L PVD+ITGPGNIYVTAAKRLCR VGIDAE Sbjct 181 LGVDEVWAVGGGQAVALLTYGGTDTDGAELAPVDLITGPGNIYVTAAKRLCRGLVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAAD+ISQAEHD +AASVLVT S +LADA D LA QLQ T Sbjct 241 AGPTEIAILADHTADPVHVAADMISQAEHDVMAASVLVTSSVELADAVDTALAAQLQITK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVTAAL+G QS VLV DV+A + VVNAYAAEHLEIQT +A VA ++ SAGA+FVG Sbjct 301 HRERVTAALSGTQSGTVLVSDVEAGLRVVNAYAAEHLEIQTENATAVAGKVTSAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+Y+E+ALK+VSGHVITLA Sbjct 361 PWAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYSESALKEVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAVR RFE Sbjct 421 NAEDLPAHGEAVRLRFE 437 >gi|229491063|ref|ZP_04384894.1| histidinol dehydrogenase [Rhodococcus erythropolis SK121] gi|229322044|gb|EEN87834.1| histidinol dehydrogenase [Rhodococcus erythropolis SK121] Length=456 Score = 664 bits (1713), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/437 (78%), Positives = 370/437 (85%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + AELRAALPRGG DV+AVL VRP+V AV +RGAEAAL+FG FDGV Sbjct 17 MLARTDLRGRTPSTAELRAALPRGGVDVDAVLHQVRPMVEAVRDRGAEAALEFGEKFDGV 76 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP A L+ AL LD V EAL+V +ERTR VH+ QRR D T + PG TVTERW Sbjct 77 RPASVRVPAAELERALRELDPAVKEALEVAIERTRTVHADQRRKDTVTEVVPGGTVTERW 136 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVVASPPQA + G+PHPTILAAA + Sbjct 137 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQADFGGLPHPTILAAAAM 196 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGG Q VALL YGGTDTDG L PVD+ITGPGNIYVTAAKRLCR VGIDAE Sbjct 197 LGVDEVWAVGGGQGVALLTYGGTDTDGTELVPVDLITGPGNIYVTAAKRLCRGLVGIDAE 256 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHD +AASVLVT S DLADA D LA QL+ T Sbjct 257 AGPTEIAILADHTADPVHVAADLISQAEHDVMAASVLVTTSVDLADAVDKALAAQLEITK 316 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVT ALTG QS VLV DV A + VVNAYAAEHLEIQT DA VA+++ SAGA+FVG Sbjct 317 HRERVTTALTGSQSGTVLVSDVSAGLRVVNAYAAEHLEIQTEDATGVAAQVTSAGAVFVG 376 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHV++Y+E+ALKDV+GHVITLA Sbjct 377 PWAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVIDYSESALKDVAGHVITLA 436 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAVR RFE Sbjct 437 NAEDLPAHGEAVRLRFE 453 >gi|226306939|ref|YP_002766899.1| histidinol dehydrogenase [Rhodococcus erythropolis PR4] gi|226186056|dbj|BAH34160.1| histidinol dehydrogenase [Rhodococcus erythropolis PR4] Length=440 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/437 (78%), Positives = 370/437 (85%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + AELRAALPRGG DV+AVL VRP+V AV +RGAEAAL+FG FDGV Sbjct 1 MLARTDLRGRTPSTAELRAALPRGGVDVDAVLHQVRPMVEAVRDRGAEAALEFGEKFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP A L+ AL LD V EAL+V +ERTR VH+ QRR D T + PG TVTERW Sbjct 61 RPASVRVPAAELERALRELDPAVKEALEVAIERTRKVHADQRRKDTVTEVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVVASPPQA + G+PHPTILAAA + Sbjct 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQADFGGLPHPTILAAAAM 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGG Q VALL YGGTDTDG L PVD+ITGPGNIYVTAAKRLCR VGIDAE Sbjct 181 LGVDEVWAVGGGQGVALLTYGGTDTDGTELVPVDLITGPGNIYVTAAKRLCRGLVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAADLISQAEHD +AASVLVT S +LADA D LA QL+ T Sbjct 241 AGPTEIAILADHTADPVHVAADLISQAEHDVMAASVLVTTSVELADAVDKALAAQLEITK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVT ALTG QS VLV DV A + VVNAYAAEHLEIQT DA VA+++ SAGA+FVG Sbjct 301 HRERVTTALTGSQSGTVLVSDVSAGLRVVNAYAAEHLEIQTEDATGVAAQVTSAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHV++Y+E+ALKDV+GHVITLA Sbjct 361 PWAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVIDYSESALKDVAGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAVR RFE Sbjct 421 NAEDLPAHGEAVRLRFE 437 >gi|111018044|ref|YP_701016.1| histidinol dehydrogenase [Rhodococcus jostii RHA1] gi|110817574|gb|ABG92858.1| histidinol dehydrogenase [Rhodococcus jostii RHA1] Length=440 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/437 (78%), Positives = 372/437 (86%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + AELRAALPRGG DV+AVL VRP+V AV ERGA+AAL+F FDGV Sbjct 1 MLARTDLRGRTPSTAELRAALPRGGVDVDAVLHQVRPVVEAVRERGADAALEFSEKFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 P +RVP + LD AL LD V AL+V +ERTR VH+ QRRTD TT + PG TVTERW Sbjct 61 SPAQVRVPQSELDRALGELDPAVRAALEVAIERTRKVHADQRRTDTTTEVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV+RVGLYVPGGNAVYPSSVVMNVVPAQAAGV SLVVASPPQ+ + G+PHPTILAAA L Sbjct 121 VPVDRVGLYVPGGNAVYPSSVVMNVVPAQAAGVRSLVVASPPQSDFGGLPHPTILAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGG QAVALL YGGTDT+GA L PVD+ITGPGNIYVTAAKRLCR VGIDAE Sbjct 181 LGVDEVWAVGGGQAVALLTYGGTDTNGAELAPVDLITGPGNIYVTAAKRLCRGLVGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILADHTADPVHVAAD+ISQAEHD +AASVLVT S +LADA D LA QL T Sbjct 241 AGPTEIAILADHTADPVHVAADMISQAEHDVMAASVLVTSSVELADAVDTALAAQLAITK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H+ERVTAAL+G QS VLV DV+A + VVNAYAAEHLEIQT +A VA+++ SAGA+FVG Sbjct 301 HKERVTAALSGTQSGTVLVSDVEAGLRVVNAYAAEHLEIQTENATAVAAKVTSAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 PW+PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVV+Y+E+ALK+VSGHVITLA Sbjct 361 PWAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYSESALKEVSGHVITLA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAVR RFE Sbjct 421 NAEDLPAHGEAVRLRFE 437 >gi|333919109|ref|YP_004492690.1| Histidinol dehydrogenase [Amycolicicoccus subflavus DQS3-9A1] gi|333481330|gb|AEF39890.1| Histidinol dehydrogenase [Amycolicicoccus subflavus DQS3-9A1] Length=446 Score = 630 bits (1625), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 325/435 (75%), Positives = 361/435 (83%), Gaps = 0/435 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 L R+DLR T AELRA+LPRGG DV++VL VRP+V AV +RGA+AAL+FG FD VR Sbjct 7 LGRLDLRDRTPTTAELRASLPRGGVDVDSVLHHVRPVVEAVRDRGADAALEFGEKFDRVR 66 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P IRVP LD +L GLD V +AL+V ++R R VH QRRTD T + PG TVTERW+ Sbjct 67 PDRIRVPAEELDKSLTGLDPRVRDALEVAIDRARTVHRDQRRTDTATEVVPGGTVTERWI 126 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 V+RVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVV SPPQA++ G+PHPTILAAA LL Sbjct 127 AVDRVGLYVPGGNAVYPSSVVMNVVPAQEAGVGSLVVTSPPQAEFGGLPHPTILAAAALL 186 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GVDEVWAVGGAQAVALL YGGTD DGA L PVDMITGPGNIYVTAAKRLCRS VGIDAEA Sbjct 187 GVDEVWAVGGAQAVALLTYGGTDCDGAELEPVDMITGPGNIYVTAAKRLCRSLVGIDAEA 246 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILAD TADP HVAADLISQAEHD LAASVLVT SE+LADA D +A QL TT H Sbjct 247 GPTEIAILADDTADPRHVAADLISQAEHDVLAASVLVTTSEELADAVDRAVAEQLHTTKH 306 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 +ERV AL+G+QS IVLV +D + VNAYAAEHLEIQT DA +A +IR+AGAIFVGP Sbjct 307 QERVATALSGKQSGIVLVSTIDDGIRAVNAYAAEHLEIQTRDAAAIAGKIRAAGAIFVGP 366 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 SPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFL+G+HV+EY+E AL+DV+ HVI LA Sbjct 367 HSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLKGVHVIEYSEDALRDVARHVIALAH 426 Query 422 AEDLPAHGEAVRRRF 436 AEDLPAHG+AVR RF Sbjct 427 AEDLPAHGDAVRARF 441 >gi|54023813|ref|YP_118055.1| histidinol dehydrogenase [Nocardia farcinica IFM 10152] gi|81823167|sp|Q5YYQ0.1|HISX_NOCFA RecName: Full=Histidinol dehydrogenase; Short=HDH gi|54015321|dbj|BAD56691.1| putative histidinol dehydrogenase [Nocardia farcinica IFM 10152] Length=445 Score = 621 bits (1601), Expect = 9e-176, Method: Compositional matrix adjust. Identities = 333/436 (77%), Positives = 361/436 (83%), Gaps = 0/436 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 L R+DLRG + AELRAALPRGG DV++VL VRP+V AV ERGA AAL+FG FDGV Sbjct 7 LARVDLRGRTPSTAELRAALPRGGVDVDSVLHHVRPVVEAVRERGAAAALEFGEKFDGVV 66 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P +RVP A L AL LD V AL+ + R R VH+ QRRTD TT + PG TVTERWV Sbjct 67 PATVRVPAAELARALDELDPAVRAALEESIARARRVHADQRRTDTTTEVVPGGTVTERWV 126 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PV RVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVVASPPQA + G+PHPTILAAA LL Sbjct 127 PVARVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQANFGGLPHPTILAAAALL 186 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GV+EVWAVGGAQAVALL+YGGTDTDGA L PVD+ITGPGNIYVTAAKRLCR VGIDAEA Sbjct 187 GVEEVWAVGGAQAVALLSYGGTDTDGAPLDPVDLITGPGNIYVTAAKRLCRGLVGIDAEA 246 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILAD TADP HVAADLISQAEHD LAASVLVT S LADA DA L QL H Sbjct 247 GPTEIAILADATADPAHVAADLISQAEHDVLAASVLVTDSVALADAVDAALTAQLAVVKH 306 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 ERV ALTG+QS VLVDD+ + VV+AYAAEHLEIQTADA VA+R+RSAGA+FVGP Sbjct 307 AERVRTALTGKQSGTVLVDDITQGLRVVDAYAAEHLEIQTADASAVAARVRSAGAVFVGP 366 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 ++PVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDV+GHV+ LA Sbjct 367 YAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVAGHVVALAD 426 Query 422 AEDLPAHGEAVRRRFE 437 AEDLPAHG+AV RFE Sbjct 427 AEDLPAHGQAVTVRFE 442 >gi|296139731|ref|YP_003646974.1| histidinol dehydrogenase [Tsukamurella paurometabola DSM 20162] gi|296027865|gb|ADG78635.1| histidinol dehydrogenase [Tsukamurella paurometabola DSM 20162] Length=448 Score = 602 bits (1553), Expect = 3e-170, Method: Compositional matrix adjust. Identities = 328/436 (76%), Positives = 362/436 (84%), Gaps = 0/436 (0%) Query 2 LTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGVR 61 L R+DLRG + ELRAALPRGG DV+AV+P VRPIV AVA+RGAEAAL++GA FDGVR Sbjct 6 LNRLDLRGRRPSLTELRAALPRGGVDVDAVVPQVRPIVDAVADRGAEAALEWGARFDGVR 65 Query 62 PHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERWV 121 P +RVP AA+ ALA LD + EAL+ + R R VH+ QRRTD T + PG TVTERW+ Sbjct 66 PDTVRVPAAAIAGALAALDPAIREALETAIARVRTVHADQRRTDTVTEVVPGGTVTERWI 125 Query 122 PVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARLL 181 PV+RVGLYVPGGNAVYPSSVVMNVVPAQ AGV SLVV SP Q +DG+PHPTILAA LL Sbjct 126 PVDRVGLYVPGGNAVYPSSVVMNVVPAQIAGVGSLVVLSPAQKDFDGLPHPTILAACALL 185 Query 182 GVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAEA 241 GVDEVWA GGAQ VAL A+GGTD DGA L PVD+ITGPGNIYVTAAKRLCR VGIDAEA Sbjct 186 GVDEVWATGGAQGVALAAHGGTDIDGAELAPVDLITGPGNIYVTAAKRLCRGLVGIDAEA 245 Query 242 GPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTVH 301 GPTEIAILAD TADPVHVAADLISQAEHD +AASVLVT S +LAD D L+ QL+ T H Sbjct 246 GPTEIAILADTTADPVHVAADLISQAEHDVMAASVLVTDSVELADRVDEALSAQLERTRH 305 Query 302 RERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVGP 361 RERV AL G QS VLVDDV + VVNAYAAEHLEIQTA+A +VA+R+R+AGAIFVGP Sbjct 306 RERVDTALRGAQSGTVLVDDVTEGLAVVNAYAAEHLEIQTANAREVAARVRAAGAIFVGP 365 Query 362 WSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLAT 421 SPVSLGDY AGSNHVLPTAGCARHSSGLSVQTFLRG+HVVEY EAALKD++G VITLA Sbjct 366 HSPVSLGDYAAGSNHVLPTAGCARHSSGLSVQTFLRGVHVVEYDEAALKDIAGIVITLAN 425 Query 422 AEDLPAHGEAVRRRFE 437 +EDLPAHGEAVR RFE Sbjct 426 SEDLPAHGEAVRLRFE 441 >gi|343926603|ref|ZP_08766102.1| histidinol dehydrogenase [Gordonia alkanivorans NBRC 16433] gi|343763473|dbj|GAA13028.1| histidinol dehydrogenase [Gordonia alkanivorans NBRC 16433] Length=458 Score = 588 bits (1515), Expect = 7e-166, Method: Compositional matrix adjust. Identities = 307/441 (70%), Positives = 351/441 (80%), Gaps = 5/441 (1%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG+ T AELR ALPRGG DV AVL TV P+V AVAE G AAL+FG FDGV Sbjct 12 MLARTDLRGSTPTLAELRRALPRGGTDVNAVLDTVTPVVHAVAETGTPAALEFGEKFDGV 71 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP + ALAGLD V +AL+ + R R VHS QRR T + G V+E+W Sbjct 72 RPTSVRVPAQVIADALAGLDAQVADALRESITRARKVHSDQRRETTRTQVVDGGVVSEKW 131 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PV RVGLYVPGGNAVYPSSV+MNVVPAQ AGV SLVVASPPQ + G PHPTILAA L Sbjct 132 IPVRRVGLYVPGGNAVYPSSVIMNVVPAQEAGVGSLVVASPPQKDFGGWPHPTILAACAL 191 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTD-----GAALTPVDMITGPGNIYVTAAKRLCRSRV 235 LGVDEVWAVGGAQ VALLAYGGTDTD GA L PVD+ITGPGNIYVTAAKRLCRS V Sbjct 192 LGVDEVWAVGGAQGVALLAYGGTDTDAADEPGAVLDPVDLITGPGNIYVTAAKRLCRSVV 251 Query 236 GIDAEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQ 295 GID+EAGPTEIAILAD +AD +A+DLISQAEHD LAASVLVT S +LADA D L Q Sbjct 252 GIDSEAGPTEIAILADDSADAGIIASDLISQAEHDVLAASVLVTASAELADAVDVALEQQ 311 Query 296 LQTTVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAG 355 + T HRERVT AL+G QS IVLVDDV+A + VV+AYAAEHLEIQT DA VA R+ +AG Sbjct 312 VAATKHRERVTTALSGEQSGIVLVDDVEAGLAVVDAYAAEHLEIQTRDAAAVADRVHNAG 371 Query 356 AIFVGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGH 415 AIFVGP++PVSLGDYCAGSNHVLPT+G AR +SGLSVQTFL+G+HV++Y EAAL++V+ Sbjct 372 AIFVGPYAPVSLGDYCAGSNHVLPTSGSARFASGLSVQTFLKGVHVIDYDEAALREVADK 431 Query 416 VITLATAEDLPAHGEAVRRRF 436 V+TLA AEDLP HG+AV++RF Sbjct 432 VVTLADAEDLPGHGDAVKQRF 452 >gi|319950574|ref|ZP_08024483.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Dietzia cinnamea P4] gi|319435768|gb|EFV90979.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Dietzia cinnamea P4] Length=446 Score = 587 bits (1513), Expect = 1e-165, Method: Compositional matrix adjust. Identities = 306/437 (71%), Positives = 348/437 (80%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L+RIDLRG L AELR LPRG ADV++V+ TVRP+V AV E GA AALD G FD V Sbjct 1 MLSRIDLRGRSLGTAELRRTLPRGAADVDSVVDTVRPVVEAVREHGAGAALDHGEKFDSV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP + A LD D+ AL + R R VHS QRR+D T + PG VTE+W Sbjct 61 RPASVRVPADVIARAAEELDPDIRAALAEAIRRARIVHSAQRRSDSVTEVAPGGFVTEKW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLYVPGG AVYPSSV+MNVVPAQ AGV SLVV+SPPQA + G PHPTILAA L Sbjct 121 VPVERVGLYVPGGKAVYPSSVIMNVVPAQVAGVGSLVVSSPPQADFGGWPHPTILAACSL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYGG DTDG AL PVDM+TGPGN+YVTAAKRLCRS VGID+E Sbjct 181 LGVDEVWAVGGAQAVALLAYGGEDTDGEALEPVDMVTGPGNVYVTAAKRLCRSVVGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIA+LAD TADPVHVA DLISQAEHD AASVLVT SE LADA D E+ + T+ Sbjct 241 AGPTEIAVLADETADPVHVAYDLISQAEHDPNAASVLVTDSELLADAVDREIEARYDVTL 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 + ERV AL G QS IVLVDD+DA + VV+AYAAEHLE+QT D+ A+R+R+AGA+FVG Sbjct 301 NSERVREALEGPQSGIVLVDDIDAGLKVVDAYAAEHLEVQTRDSAADAARVRNAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 +SPV LGDY AGSNHVLPT+G ARHSSGLSVQTFLRGIHVV+Y +AALK+++ V+ LA Sbjct 361 AYSPVPLGDYAAGSNHVLPTSGTARHSSGLSVQTFLRGIHVVDYDQAALKEIAPTVVALA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AE LPAHGEAVR RFE Sbjct 421 DAERLPAHGEAVRARFE 437 >gi|302525409|ref|ZP_07277751.1| histidinol dehydrogenase [Streptomyces sp. AA4] gi|302434304|gb|EFL06120.1| histidinol dehydrogenase [Streptomyces sp. AA4] Length=441 Score = 584 bits (1506), Expect = 8e-165, Method: Compositional matrix adjust. Identities = 303/437 (70%), Positives = 351/437 (81%), Gaps = 0/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG +AAELRAALPR DV+A L VRP+V AV +RG A L+F FD V Sbjct 1 MLNRTDLRGQVPSAAELRAALPRAEYDVDAALHQVRPVVEAVRDRGVGAVLEFTERFDKV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP L AL+ LD V AL+ ++R R VH+ QRR DVTT + PG TVTERW Sbjct 61 RPETVRVPAEELAKALSELDPQVRAALEESIKRARKVHADQRRQDVTTQVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLY PGG AVYPS+VVMNVVPAQ AGV SLVV SPPQA + G PHPTILAAA L Sbjct 121 VPVERVGLYAPGGLAVYPSTVVMNVVPAQLAGVRSLVVCSPPQAAFGGRPHPTILAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVAL+AYGG DTDGA L PVD++TGPGNI++TAAKRL R +GID+E Sbjct 181 LGVDEVWAVGGAQAVALVAYGGVDTDGAELAPVDIVTGPGNIFLTAAKRLVRGVIGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD TADP HVAADLISQAEHD LAASVLVT SE+LADA +AELA ++ T Sbjct 241 AGPTEIAILADETADPAHVAADLISQAEHDPLAASVLVTTSEELADAVEAELAERVAATK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERV AL G+QS ++LV VD + VV+AYAAEHLEIQTA+A +VA+R+R+AGA+FVG Sbjct 301 HSERVGQALGGKQSGVILVSTVDDGLRVVDAYAAEHLEIQTANAREVAARVRNAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 ++PVSLGDYCAGSNHVLPT G ARHSSGLSVQ+FL+GIHVV+Y+E AL++++ V+ LA Sbjct 361 AYAPVSLGDYCAGSNHVLPTGGFARHSSGLSVQSFLKGIHVVDYSEDALREIAPRVVALA 420 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHGEAV RFE Sbjct 421 NAEDLPAHGEAVTARFE 437 >gi|257055138|ref|YP_003132970.1| histidinol dehydrogenase [Saccharomonospora viridis DSM 43017] gi|256585010|gb|ACU96143.1| histidinol dehydrogenase [Saccharomonospora viridis DSM 43017] Length=444 Score = 582 bits (1500), Expect = 4e-164, Method: Compositional matrix adjust. Identities = 308/438 (71%), Positives = 347/438 (80%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG + A+LRA LPR DV+AVL VRP+V AV ERG +A LD+ FD V Sbjct 1 MLKRTDLRGRVPSPAQLRALLPRAEVDVDAVLHQVRPVVDAVRERGVDAVLDYTERFDAV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP +++ALA LD V EAL+ + R RAVH+ QRR DVTT + G TVTERW Sbjct 61 RPDRVRVPAREMESALASLDPVVREALEESIARARAVHADQRREDVTTRVVDGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV RVGLY PGG AVYPSSVVMNVVPAQ AGV SLV+ SPPQA++ G+PHPTILAAA L Sbjct 121 VPVSRVGLYAPGGLAVYPSSVVMNVVPAQTAGVGSLVLCSPPQAEFGGLPHPTILAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVD+VWAVGGAQAVALLAYGGTDTDG L PVDM+TGPGNIY+TAAKRL R +GID+E Sbjct 181 LGVDDVWAVGGAQAVALLAYGGTDTDGTELEPVDMVTGPGNIYLTAAKRLLRGLIGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD TADP HVAADLISQAEHD LAASVLVT SE LADA D EL ++ T Sbjct 241 AGPTEIAILADDTADPAHVAADLISQAEHDTLAASVLVTTSEALADAVDEELRRRVAATK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERV AL G QS VLV VD + VV+AYAAEHL IQTA+A +VA+R+R+AGAIFVG Sbjct 301 HTERVEQALRGAQSGTVLVSTVDDGLRVVDAYAAEHLAIQTANAREVAARVRNAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P+SPVSLGDYCAGSNHVLPT G ARHSSGLSVQ+FLRGIHVV+Y E AL+DV+ V+ LA Sbjct 361 PYSPVSLGDYCAGSNHVLPTGGFARHSSGLSVQSFLRGIHVVDYNEQALRDVADKVVALA 420 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHGEAV R R Sbjct 421 NAEDLPAHGEAVMARTGR 438 >gi|300784161|ref|YP_003764452.1| histidinol dehydrogenase [Amycolatopsis mediterranei U32] gi|299793675|gb|ADJ44050.1| histidinol dehydrogenase [Amycolatopsis mediterranei U32] gi|340525578|gb|AEK40783.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Amycolatopsis mediterranei S699] Length=441 Score = 578 bits (1491), Expect = 5e-163, Method: Compositional matrix adjust. Identities = 313/436 (72%), Positives = 352/436 (81%), Gaps = 0/436 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG TAAELRA LPR DV+A L VRP+V AV +RG EA L++ FD V Sbjct 1 MLNRTDLRGQVPTAAELRATLPRAEYDVDAALHHVRPVVEAVRDRGVEAVLEYTEKFDKV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP AAL AL LD V AL+ + R R VH+ QRRTDVTTT+ G TVTE+W Sbjct 61 RPASVRVPRAALTRALEELDPAVRAALEESIARARKVHAEQRRTDVTTTVVEGGTVTEKW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPVERVGLY PGG AVYPS+VVMNVVPAQ AGV SLVV SPPQA +DG+PHPTILAAA L Sbjct 121 VPVERVGLYAPGGLAVYPSTVVMNVVPAQIAGVGSLVVCSPPQAAFDGLPHPTILAAAEL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWA GGAQAVALLAYGGTDTDGA L PVD++TGPGNIY+TAAKRL R +GIDAE Sbjct 181 LGVDEVWAAGGAQAVALLAYGGTDTDGAELAPVDIVTGPGNIYLTAAKRLLRGLIGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD TADPVHVAADLISQAEHD LAASVLVT S +LADA D EL ++ T Sbjct 241 AGPTEIAILADETADPVHVAADLISQAEHDPLAASVLVTTSVELADAVDKELVNRVAATK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERV AL G+QS I+LV VD + VV+AYAAEHLEIQTADA VA+R+R+AGAIFVG Sbjct 301 HTERVAEALAGKQSGIILVSTVDDGLRVVDAYAAEHLEIQTADARAVAARVRNAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 ++PVSLGDYCAGSNHVLPT G ARHSSGLSVQ+FL+GIHVV+YTE AL++V+G V+ LA Sbjct 361 AYAPVSLGDYCAGSNHVLPTGGFARHSSGLSVQSFLKGIHVVDYTEDALREVAGRVVALA 420 Query 421 TAEDLPAHGEAVRRRF 436 AEDLPAHGEAV RF Sbjct 421 DAEDLPAHGEAVTARF 436 >gi|262202853|ref|YP_003274061.1| histidinol dehydrogenase [Gordonia bronchialis DSM 43247] gi|262086200|gb|ACY22168.1| histidinol dehydrogenase [Gordonia bronchialis DSM 43247] Length=441 Score = 577 bits (1486), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 297/436 (69%), Positives = 346/436 (80%), Gaps = 0/436 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R DLRG+ T A+LR ALPRGG DV AVL TV P+V AVAE G EAAL +G FDGV Sbjct 1 MLARTDLRGSTPTLAQLRRALPRGGTDVNAVLDTVEPVVHAVAEHGVEAALSYGERFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP A+ AL LD + +AL+ + R R VH+ QRR T + G V+E+W Sbjct 61 RPASVRVPADAISEALERLDPAIADALRESITRARKVHADQRRETTRTQVVDGGVVSEKW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PV RVGLYVPGGNAVYPSSV+MNVVPAQ AGV SLVVASPPQ + G PHPTILAA L Sbjct 121 IPVRRVGLYVPGGNAVYPSSVIMNVVPAQEAGVGSLVVASPPQKDFGGWPHPTILAACAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQ +ALL YGG +TDG+ L PVD+ITGPGNIYVTAAKRLCR VGID+E Sbjct 181 LGVDEVWAVGGAQGIALLTYGGEETDGSVLDPVDLITGPGNIYVTAAKRLCRGVVGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD +AD +A+DLISQAEHD LAASVLVT S +LADA DA L Q+ T Sbjct 241 AGPTEIAILADDSADAGILASDLISQAEHDVLAASVLVTDSAELADAVDAALEQQVAATK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRERVT AL+G QS IVLVDD++A + VV+AYAAEHLEIQT DA VA R+ +AGAIFVG Sbjct 301 HRERVTTALSGEQSGIVLVDDLEAGLAVVDAYAAEHLEIQTRDAATVADRVHNAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P++PVSLGDYCAGSNHVLPT+G AR +SGLSVQTFL+G+HV++Y EAAL+ V+ V+TLA Sbjct 361 PYAPVSLGDYCAGSNHVLPTSGSARFASGLSVQTFLKGVHVIDYDEAALRSVADKVVTLA 420 Query 421 TAEDLPAHGEAVRRRF 436 AEDLP HG+AV +RF Sbjct 421 DAEDLPGHGDAVTQRF 436 >gi|134102227|ref|YP_001107888.1| histidinol dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|291003811|ref|ZP_06561784.1| histidinol dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|133914850|emb|CAM04963.1| histidinol dehydrogenase [Saccharopolyspora erythraea NRRL 2338] Length=438 Score = 568 bits (1464), Expect = 7e-160, Method: Compositional matrix adjust. Identities = 307/436 (71%), Positives = 344/436 (79%), Gaps = 0/436 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTR DLRG + AELRA LPR DVE VL VRP++ +V + G A LD FD V Sbjct 1 MLTRTDLRGRVPSNAELRATLPRAEMDVEHVLHQVRPVIESVRDDGVRAVLDHTEKFDRV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RV L AL LD V AL+ + R R VH+ QRRTD TT + PG TVTERW Sbjct 61 RPERVRVGADELRRALDELDPAVRSALEESIARARKVHADQRRTDTTTRVAPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV RVGLY PGG AVYPSSVVMNVVPAQAAGV+SLVV SPPQA++ G+PHPTILAAA L Sbjct 121 VPVARVGLYAPGGLAVYPSSVVMNVVPAQAAGVESLVVCSPPQAEFGGLPHPTILAAAEL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQAVALLAYG DTDGAAL P DM+TGPGN+YVTAAKR RS +GID+E Sbjct 181 LGVDEVWAVGGAQAVALLAYGAEDTDGAALEPADMVTGPGNVYVTAAKRHLRSLIGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIA+LAD TADPVHVAADLISQAEHD LAASVLVT SE LADA DAELA Q+ T Sbjct 241 AGPTEIAVLADDTADPVHVAADLISQAEHDTLAASVLVTTSERLADAVDAELARQVPLTK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ER+ ALT QS +LV + + VV+AYAAEHLEIQTADA VA+R+R+AGAIFVG Sbjct 301 HTERIRTALTSVQSGCILVAGIADGIRVVDAYAAEHLEIQTADADAVAARVRNAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P++PVSLGDYCAGSNHVLPT GCARHSSGLSVQ+FLRGIHV+ YTE AL+DV+G V+ LA Sbjct 361 PYAPVSLGDYCAGSNHVLPTGGCARHSSGLSVQSFLRGIHVISYTEQALRDVAGQVVALA 420 Query 421 TAEDLPAHGEAVRRRF 436 AEDLPAHG+AV RF Sbjct 421 DAEDLPAHGQAVTARF 436 >gi|326382622|ref|ZP_08204313.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326198741|gb|EGD55924.1| bifunctional histidinal dehydrogenase/ histidinol dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=441 Score = 561 bits (1446), Expect = 9e-158, Method: Compositional matrix adjust. Identities = 296/436 (68%), Positives = 336/436 (78%), Gaps = 0/436 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +LTR DLRG+ T ++LR ALPRGG DV AVLPTV P+V A+AE GA AALD+ FD V Sbjct 1 MLTRTDLRGSTPTLSQLRRALPRGGTDVNAVLPTVTPVVEAIAEHGASAALDYTEKFDKV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP + A A LD V +AL+ + R R VH+ QRR T + PG TV E+W Sbjct 61 RPGSVRVPADVIAKARADLDPAVTDALEESIRRARLVHADQRRQTSVTEVVPGGTVAEKW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PV RVGLYVPGGNAVYPSSV+MNVVPAQ AGV SLVVASP QA + G PHPTILAA L Sbjct 121 IPVRRVGLYVPGGNAVYPSSVIMNVVPAQEAGVGSLVVASPAQADFGGWPHPTILAACSL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEVWAVGGAQ VALLAYGG DTDG L PVD+ITGPGNIYVTAAKRL R VGID+E Sbjct 181 LGVDEVWAVGGAQGVALLAYGGEDTDGGVLDPVDLITGPGNIYVTAAKRLVRGVVGIDSE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEI ILAD +AD VA+DLISQAEHD LAASVLVT S LADA D + T Sbjct 241 AGPTEITILADDSADAAVVASDLISQAEHDVLAASVLVTDSVALADAVDEAVERAASATK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERV AL G QS IVLVDDVDA + VV+AYAAEHLEIQT DA VA R+ SAGAIFVG Sbjct 301 HSERVKTALAGPQSGIVLVDDVDAGLAVVDAYAAEHLEIQTRDAQAVADRVTSAGAIFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 +SPVSLGDY AGSNHVLPT+G A+++SGLSVQTFLRG+HV++Y AL +++ V+TLA Sbjct 361 TYSPVSLGDYSAGSNHVLPTSGSAKYASGLSVQTFLRGVHVIDYDRDALAEIADRVVTLA 420 Query 421 TAEDLPAHGEAVRRRF 436 AEDLPAHGEAV+ RF Sbjct 421 NAEDLPAHGEAVQARF 436 >gi|256379723|ref|YP_003103383.1| histidinol dehydrogenase [Actinosynnema mirum DSM 43827] gi|255924026|gb|ACU39537.1| histidinol dehydrogenase [Actinosynnema mirum DSM 43827] Length=438 Score = 549 bits (1414), Expect = 4e-154, Method: Compositional matrix adjust. Identities = 311/438 (72%), Positives = 351/438 (81%), Gaps = 0/438 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L R+DLRG +AAELRAALPR DV+AVL VRP+V V +RG EA L+ FDGV Sbjct 1 MLNRVDLRGRVPSAAELRAALPRAEVDVDAVLHQVRPLVQDVRDRGVEAVLEHTERFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +RVP LDAALAGLD +V AL+ + R RAVH+ QRRTD TT + PG TVTERW Sbjct 61 RPERVRVPQVELDAALAGLDPEVRAALEESIARARAVHADQRRTDTTTRVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV RVGLY PGG AVYPSSVVMNVVPAQ AGV+SLVV SPPQA + G+PHPT+LAAA L Sbjct 121 VPVRRVGLYAPGGLAVYPSSVVMNVVPAQTAGVESLVVCSPPQADFGGLPHPTVLAAAAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGV EVWAVGGA AVALLA+GG DT G L VD++TGPGNIY+TAAKRL R +GIDAE Sbjct 181 LGVTEVWAVGGALAVALLAHGGVDTTGDELEAVDLVTGPGNIYLTAAKRLLRGLIGIDAE 240 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIA+LAD TADPVHVAADLISQAEHD LAA+VLVT SE LADA DA LA + T Sbjct 241 AGPTEIAVLADETADPVHVAADLISQAEHDPLAAAVLVTTSEPLADAVDAALARLVPETK 300 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ERV ALTG QS +VLV VD + VV+AYAAEHLE+QTADA VA+R+R+AGA+FVG Sbjct 301 HHERVRTALTGGQSGVVLVSTVDDGLRVVDAYAAEHLEVQTADAAAVAARVRAAGAVFVG 360 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P SPVSLGDYCAGSNHVLPT GCARHSSGLSVQTFLRGIHVV+Y+E AL++V+ V+ LA Sbjct 361 PHSPVSLGDYCAGSNHVLPTGGCARHSSGLSVQTFLRGIHVVDYSEDALREVAAKVVALA 420 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHG+AV RF R Sbjct 421 EAEDLPAHGQAVTARFAR 438 >gi|38234141|ref|NP_939908.1| histidinol dehydrogenase [Corynebacterium diphtheriae NCTC 13129] gi|46395651|sp|P60858.1|HISX_CORDI RecName: Full=Histidinol dehydrogenase; Short=HDH gi|38200403|emb|CAE50091.1| histidinol dehydrogenase [Corynebacterium diphtheriae] Length=449 Score = 548 bits (1411), Expect = 9e-154, Method: Compositional matrix adjust. Identities = 285/440 (65%), Positives = 338/440 (77%), Gaps = 2/440 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L IDLRG T +ELR LPRGG D+ +VLP V P+V V RGA AALD+G FD V Sbjct 7 MLNVIDLRGHVPTTSELRRTLPRGGTDINSVLPIVEPVVTDVKNRGAAAALDYGEKFDHV 66 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP +IRVP +D AL LD +V EAL+ + R RAVHS Q TT+ G GAT+TE++ Sbjct 67 RPTSIRVPQDVIDQALDSLDPNVIEALKESIARVRAVHSEQLPAQHTTSFGEGATITEKF 126 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PV RVGLY PGGNAVYPSSV+MNVVPAQ AGV+SLVVASPPQ G PHPTILAAA+L Sbjct 127 IPVSRVGLYAPGGNAVYPSSVIMNVVPAQEAGVESLVVASPPQKDHGGWPHPTILAAAKL 186 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAA--LTPVDMITGPGNIYVTAAKRLCRSRVGID 238 LGV EVWA+GGAQAVALLAYG +A L PVDMITGPGNI+VTAAKRL R VGID Sbjct 187 LGVTEVWAMGGAQAVALLAYGDDTQQNSAEVLEPVDMITGPGNIFVTAAKRLVRGVVGID 246 Query 239 AEAGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQT 298 +EAGPTEIAI+AD A+PV +A DLISQAEHD LAASVL+T SE+LA + E+A + Sbjct 247 SEAGPTEIAIVADAQANPVWIAYDLISQAEHDVLAASVLITDSEELAQRVNEEVAARYSV 306 Query 299 TVHRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIF 358 T + +RV+ AL G+QS IVLVDD+ AV+V +AYAAEHLEI TA++ +VA +IR+AGAIF Sbjct 307 TRNADRVSEALKGQQSGIVLVDDLPTAVIVADAYAAEHLEIHTAESHKVAEQIRNAGAIF 366 Query 359 VGPWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVIT 418 VG +SPV LGDY AGSNHVLPT+G AR+SSGLS TFL+ ++V+ Y E ALK++S VIT Sbjct 367 VGGYSPVPLGDYSAGSNHVLPTSGSARYSSGLSTHTFLKPVNVIYYDEVALKEISDTVIT 426 Query 419 LATAEDLPAHGEAVRRRFER 438 LA AEDLPAHGEA+R RFE Sbjct 427 LADAEDLPAHGEAIRTRFEN 446 >gi|269127110|ref|YP_003300480.1| histidinol dehydrogenase [Thermomonospora curvata DSM 43183] gi|268312068|gb|ACY98442.1| histidinol dehydrogenase [Thermomonospora curvata DSM 43183] Length=435 Score = 546 bits (1407), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 289/437 (67%), Positives = 339/437 (78%), Gaps = 7/437 (1%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +++RIDLRG+ +LR+ LPR DVEA L VRPI V RGA A ++ FDGV Sbjct 1 MISRIDLRGS--LPGDLRSVLPRAELDVEAALERVRPICEDVRHRGAAAVREYTKKFDGV 58 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 ++RVP AAL+ ALAGLD V +AL+ + R R VH QRRTDVTT + PG TVTERW Sbjct 59 ELESLRVPAAALERALAGLDPAVRDALEESIRRARLVHRDQRRTDVTTQVVPGGTVTERW 118 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PVERVGLYVPGG AVYPSSVVMNVVPAQ AGV SL V SPPQ ++ G+PHP ILAA L Sbjct 119 IPVERVGLYVPGGRAVYPSSVVMNVVPAQEAGVGSLAVTSPPQQEFGGLPHPAILAACAL 178 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGV+EV+A GGAQ++A+LAYG TD PV+++TGPGNI+V AAKR R VGID+E Sbjct 179 LGVEEVYAAGGAQSIAMLAYG-TDE----CRPVNLVTGPGNIWVAAAKRHLRGVVGIDSE 233 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD +ADPVHVAADLISQAEHD LAA+VLVT SE+LA+ + ELA Q+ T Sbjct 234 AGPTEIAILADASADPVHVAADLISQAEHDTLAAAVLVTDSEELAERVERELAEQVARTK 293 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 H ER+T AL GRQS IVLVDD++A + VVNAYAAEHLEIQTA+A QVA R+R+AGAIF+G Sbjct 294 HTERITQALAGRQSGIVLVDDIEAGLAVVNAYAAEHLEIQTANARQVAERVRNAGAIFIG 353 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 P SPVSLGDY AGSNHVLPT GCA HSSGLSVQ+FLRG+HVVEY AAL + + V+ LA Sbjct 354 PHSPVSLGDYLAGSNHVLPTGGCACHSSGLSVQSFLRGVHVVEYDRAALAEATARVVALA 413 Query 421 TAEDLPAHGEAVRRRFE 437 AEDLPAHG A++ RF Sbjct 414 EAEDLPAHGAAMKARFN 430 >gi|213965263|ref|ZP_03393460.1| histidinol dehydrogenase [Corynebacterium amycolatum SK46] gi|213952115|gb|EEB63500.1| histidinol dehydrogenase [Corynebacterium amycolatum SK46] Length=449 Score = 545 bits (1405), Expect = 4e-153, Method: Compositional matrix adjust. Identities = 278/437 (64%), Positives = 335/437 (77%), Gaps = 3/437 (0%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 +L+ IDLRG T A LR LPRG ADV++++PTV+P+V VA RG EAA+++ FD + Sbjct 1 MLSTIDLRGQTPTTATLRRVLPRGAADVDSMIPTVKPVVDDVAARGVEAAMEYSEKFDRI 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP ++RVP +DAA A L+ DV ALQ + R RA H+ Q+ D T L PG V E+W Sbjct 61 RPVSMRVPAEVIDAAEAALEDDVRSALQESIGRVRAFHAAQKPNDKTVELLPGGIVREKW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 +PV RVGLYVPGGNAVYPSSV+MNV+PAQ AGV+SLVVASPPQA DG PHPTILAA +L Sbjct 121 IPVSRVGLYVPGGNAVYPSSVLMNVIPAQEAGVESLVVASPPQADNDGWPHPTILAACKL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGV EVWAVGGAQAVALLAYG + +L PVDM+TGPGNI+VTAAKRLCRS VGIDAE Sbjct 181 LGVTEVWAVGGAQAVALLAYG---DENESLEPVDMVTGPGNIFVTAAKRLCRSVVGIDAE 237 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD+TADPV VA DLISQAEHD +AASVL+T D A D E+ + + T+ Sbjct 238 AGPTEIAILADNTADPVSVAYDLISQAEHDVMAASVLITDDADFAATVDREVENRYEVTM 297 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 + +RV ALTG QS IVLVDD++ + V +AYAAEHLEI T +A A RI +AGAIF+G Sbjct 298 NADRVREALTGDQSGIVLVDDMNIGIQVADAYAAEHLEIHTENAQADAERITNAGAIFIG 357 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 +SPV LGDY AGSNHVLPT+G ARH+SGLS TFL+ +H+++Y EAALK+V+ V+ LA Sbjct 358 RFSPVPLGDYSAGSNHVLPTSGTARHASGLSTHTFLKSVHMIDYNEAALKEVADSVVVLA 417 Query 421 TAEDLPAHGEAVRRRFE 437 E LPAHGEA+R RFE Sbjct 418 NEERLPAHGEAIRARFE 434 >gi|72161554|ref|YP_289211.1| histidinol dehydrogenase [Thermobifida fusca YX] gi|85542046|sp|Q47QS9.1|HISX_THEFY RecName: Full=Histidinol dehydrogenase; Short=HDH gi|71915286|gb|AAZ55188.1| histidinol dehydrogenase [Thermobifida fusca YX] Length=438 Score = 543 bits (1400), Expect = 2e-152, Method: Compositional matrix adjust. Identities = 292/438 (67%), Positives = 334/438 (77%), Gaps = 8/438 (1%) Query 1 VLTRIDLRGAELTAAELRAALPRGGADVEAVLPTVRPIVAAVAERGAEAALDFGASFDGV 60 V++RIDLRG A+ RA+LPR DV + + VRPI V RG EA ++ G FDGV Sbjct 4 VISRIDLRG---NPADPRASLPRAEIDVASAVEKVRPICEDVRHRGVEALIELGERFDGV 60 Query 61 RPHAIRVPDAALDAALAGLDCDVCEALQVMVERTRAVHSGQRRTDVTTTLGPGATVTERW 120 RP IRVP AL+ ALAGLD V AL+ + R R VH QRRTD TT + PG TVTERW Sbjct 61 RPAHIRVPADALETALAGLDRTVRAALEEAIRRARIVHRDQRRTDTTTRVVPGGTVTERW 120 Query 121 VPVERVGLYVPGGNAVYPSSVVMNVVPAQAAGVDSLVVASPPQAQWDGMPHPTILAAARL 180 VPV+RVGLYVPGG AVYPSSVVMNVVPAQ AGV SL VASPPQA++ G+PHPTILAA L Sbjct 121 VPVDRVGLYVPGGRAVYPSSVVMNVVPAQEAGVPSLAVASPPQAEFGGLPHPTILAACAL 180 Query 181 LGVDEVWAVGGAQAVALLAYGGTDTDGAALTPVDMITGPGNIYVTAAKRLCRSRVGIDAE 240 LGVDEV+AVGGAQA+A+ AYG + PV M+TGPGNI+V AAKRL + +GID+E Sbjct 181 LGVDEVYAVGGAQAIAMFAYGAGEC-----APVSMVTGPGNIWVAAAKRLLKGIIGIDSE 235 Query 241 AGPTEIAILADHTADPVHVAADLISQAEHDELAASVLVTPSEDLADATDAELAGQLQTTV 300 AGPTEIAILAD TA+P +VAADLISQAEHD +AASVLVTPS LAD +AELA Q+ Sbjct 236 AGPTEIAILADDTANPAYVAADLISQAEHDVVAASVLVTPSTALADRVEAELARQVPAAK 295 Query 301 HRERVTAALTGRQSAIVLVDDVDAAVLVVNAYAAEHLEIQTADAPQVASRIRSAGAIFVG 360 HRER+T AL G QS IVLVDD+D + VVNAYA EHLE+ TADA VA+R+R+AGAIF+G Sbjct 296 HRERITQALGGPQSGIVLVDDIDHGLDVVNAYAPEHLEVMTADAQSVAARVRNAGAIFIG 355 Query 361 PWSPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVSGHVITLA 420 SPVSLGDYCAGSNHVLPT G A HSSGLSVQ+FLRGIHVVEY AAL +V+ HV+ LA Sbjct 356 DHSPVSLGDYCAGSNHVLPTGGVAVHSSGLSVQSFLRGIHVVEYDRAALAEVAHHVVALA 415 Query 421 TAEDLPAHGEAVRRRFER 438 AEDLPAHG AV R R Sbjct 416 EAEDLPAHGAAVTARIPR 433 Lambda K H 0.318 0.132 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 897400889630 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40