BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1601

Length=210
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608739|ref|NP_216117.1|  imidazoleglycerol-phosphate dehydra...   422    1e-116
gi|340626607|ref|YP_004745059.1|  putative imidazole glycerol-pho...   421    3e-116
gi|342860829|ref|ZP_08717479.1|  imidazoleglycerol-phosphate dehy...   390    8e-107
gi|296164467|ref|ZP_06847039.1|  histidine biosynthesis bifunctio...   384    3e-105
gi|254820951|ref|ZP_05225952.1|  imidazoleglycerol-phosphate dehy...   375    2e-102
gi|118617224|ref|YP_905556.1|  imidazoleglycerol-phosphate dehydr...   372    2e-101
gi|254775632|ref|ZP_05217148.1|  imidazoleglycerol-phosphate dehy...   370    9e-101
gi|15827645|ref|NP_301908.1|  imidazoleglycerol-phosphate dehydra...   369    1e-100
gi|41407393|ref|NP_960229.1|  imidazoleglycerol-phosphate dehydra...   369    2e-100
gi|169629753|ref|YP_001703402.1|  imidazoleglycerol-phosphate deh...   361    4e-98 
gi|240167973|ref|ZP_04746632.1|  imidazoleglycerol-phosphate dehy...   359    1e-97 
gi|333990785|ref|YP_004523399.1|  imidazole glycerol-phosphate de...   358    3e-97 
gi|120403790|ref|YP_953619.1|  imidazoleglycerol-phosphate dehydr...   357    5e-97 
gi|108800027|ref|YP_640224.1|  imidazoleglycerol-phosphate dehydr...   350    6e-95 
gi|145224195|ref|YP_001134873.1|  imidazoleglycerol-phosphate deh...   349    2e-94 
gi|118473296|ref|YP_887521.1|  imidazoleglycerol-phosphate dehydr...   343    9e-93 
gi|325674476|ref|ZP_08154164.1|  histidine biosynthesis bifunctio...   342    2e-92 
gi|312140047|ref|YP_004007383.1|  imidazole glycerol-phosphate de...   342    3e-92 
gi|226306937|ref|YP_002766897.1|  imidazoleglycerol-phosphate deh...   336    1e-90 
gi|111018042|ref|YP_701014.1|  imidazoleglycerol-phosphate dehydr...   335    2e-90 
gi|226360169|ref|YP_002777947.1|  imidazoleglycerol-phosphate deh...   334    5e-90 
gi|171850953|emb|CAQ00039.1|  imidazoleglycerol-phosphate dehydra...   334    6e-90 
gi|343926605|ref|ZP_08766104.1|  imidazoleglycerol-phosphate dehy...   312    2e-83 
gi|54023815|ref|YP_118057.1|  imidazoleglycerol-phosphate dehydra...   309    2e-82 
gi|296139733|ref|YP_003646976.1|  imidazoleglycerol-phosphate deh...   307    6e-82 
gi|296394238|ref|YP_003659122.1|  imidazoleglycerol-phosphate deh...   306    1e-81 
gi|258653327|ref|YP_003202483.1|  imidazoleglycerol-phosphate deh...   305    3e-81 
gi|333919111|ref|YP_004492692.1|  Imidazoleglycerol-phosphate deh...   305    3e-81 
gi|319950576|ref|ZP_08024485.1|  imidazoleglycerol-phosphate dehy...   304    6e-81 
gi|262202851|ref|YP_003274059.1|  imidazoleglycerol-phosphate deh...   304    7e-81 
gi|326382624|ref|ZP_08204315.1|  imidazoleglycerol-phosphate dehy...   300    8e-80 
gi|256379721|ref|YP_003103381.1|  imidazoleglycerol-phosphate deh...   297    6e-79 
gi|317508559|ref|ZP_07966221.1|  imidazoleglycerol-phosphate dehy...   296    1e-78 
gi|302525411|ref|ZP_07277753.1|  imidazoleglycerol-phosphate dehy...   295    4e-78 
gi|134102225|ref|YP_001107886.1|  imidazoleglycerol-phosphate deh...   293    1e-77 
gi|257055140|ref|YP_003132972.1|  imidazoleglycerol-phosphate deh...   292    2e-77 
gi|300784163|ref|YP_003764454.1|  imidazoleglycerol-phosphate deh...   290    7e-77 
gi|340794168|ref|YP_004759631.1|  Imidazoleglycerol-phosphate deh...   290    1e-76 
gi|336325385|ref|YP_004605351.1|  Imidazoleglycerol-phosphate deh...   285    3e-75 
gi|334563076|ref|ZP_08516067.1|  imidazoleglycerol-phosphate dehy...   283    9e-75 
gi|237785383|ref|YP_002906088.1|  Imidazoleglycerol-phosphate deh...   283    2e-74 
gi|300780880|ref|ZP_07090734.1|  histidine biosynthesis bifunctio...   276    2e-72 
gi|68535863|ref|YP_250568.1|  imidazoleglycerol-phosphate dehydra...   275    2e-72 
gi|172040854|ref|YP_001800568.1|  imidazoleglycerol-phosphate deh...   275    2e-72 
gi|260578045|ref|ZP_05845967.1|  imidazoleglycerol-phosphate dehy...   275    4e-72 
gi|152967119|ref|YP_001362903.1|  imidazoleglycerol-phosphate deh...   273    1e-71 
gi|300858780|ref|YP_003783763.1|  imidazoleglycerol-phosphate deh...   271    6e-71 
gi|213965232|ref|ZP_03393429.1|  imidazoleglycerol-phosphate dehy...   270    8e-71 
gi|227548953|ref|ZP_03979002.1|  imidazoleglycerol-phosphate dehy...   269    2e-70 
gi|325000028|ref|ZP_08121140.1|  imidazoleglycerol-phosphate dehy...   269    2e-70 


>gi|15608739|ref|NP_216117.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium tuberculosis 
H37Rv]
 gi|15841054|ref|NP_336091.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium tuberculosis 
CDC1551]
 gi|31792787|ref|NP_855280.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium bovis 
AF2122/97]
 85 more sequence titles
 Length=210

 Score =  422 bits (1085),  Expect = 1e-116, Method: Compositional matrix adjust.
 Identities = 210/210 (100%), Positives = 210/210 (100%), Gaps = 0/210 (0%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL
Sbjct  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG
Sbjct  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE
Sbjct  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180

Query  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            AQYKAVARALRQAVEPDPRVSGVPSTKGAL
Sbjct  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210


>gi|340626607|ref|YP_004745059.1| putative imidazole glycerol-phosphate dehydratase hisB [Mycobacterium 
canettii CIPT 140010059]
 gi|340004797|emb|CCC43941.1| putative imidazole glycerol-phosphate dehydratase hisB [Mycobacterium 
canettii CIPT 140010059]
Length=210

 Score =  421 bits (1083),  Expect = 3e-116, Method: Compositional matrix adjust.
 Identities = 209/210 (99%), Positives = 210/210 (100%), Gaps = 0/210 (0%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL
Sbjct  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG
Sbjct  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            RPYCVHTGEPDHLQH+TIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE
Sbjct  121  RPYCVHTGEPDHLQHSTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180

Query  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            AQYKAVARALRQAVEPDPRVSGVPSTKGAL
Sbjct  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210


>gi|342860829|ref|ZP_08717479.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium colombiense 
CECT 3035]
 gi|342131853|gb|EGT85110.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium colombiense 
CECT 3035]
Length=206

 Score =  390 bits (1001),  Expect = 8e-107, Method: Compositional matrix adjust.
 Identities = 192/205 (94%), Positives = 196/205 (96%), Gaps = 0/205 (0%)

Query  6    TAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRAT  65
            TA A+RRARIERRT+ESDIVIELDLDGTGQV +DTGVPFYDHMLTALGSHASFDLTVR  
Sbjct  2    TATATRRARIERRTKESDIVIELDLDGTGQVDIDTGVPFYDHMLTALGSHASFDLTVRTK  61

Query  66   GDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCV  125
            GDVEIE HHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVD+SGRPYCV
Sbjct  62   GDVEIEGHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDVSGRPYCV  121

Query  126  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  185
            HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITEAQYKA
Sbjct  122  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKA  181

Query  186  VARALRQAVEPDPRVSGVPSTKGAL  210
            VARALRQAVE DPRVS VPSTKG L
Sbjct  182  VARALRQAVESDPRVSDVPSTKGVL  206


>gi|296164467|ref|ZP_06847039.1| histidine biosynthesis bifunctional protein HisB [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295900165|gb|EFG79599.1| histidine biosynthesis bifunctional protein HisB [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=206

 Score =  384 bits (987),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 189/205 (93%), Positives = 195/205 (96%), Gaps = 0/205 (0%)

Query  6    TAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRAT  65
            T  A+RRARIERRT+ESDIV+ELDLDGTG+V VDTGVPFYDHMLTALG+HASFDLTVR  
Sbjct  2    TTLATRRARIERRTKESDIVVELDLDGTGRVQVDTGVPFYDHMLTALGTHASFDLTVRTQ  61

Query  66   GDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCV  125
            GDVEIE HHTIEDTAIALG AL QALGDKRGIRRFGDAFIPMDETLAHAAVD+SGRPYCV
Sbjct  62   GDVEIEGHHTIEDTAIALGQALDQALGDKRGIRRFGDAFIPMDETLAHAAVDVSGRPYCV  121

Query  126  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  185
            HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA
Sbjct  122  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  181

Query  186  VARALRQAVEPDPRVSGVPSTKGAL  210
            VARALRQAVEPDPRVS VPSTKG L
Sbjct  182  VARALRQAVEPDPRVSDVPSTKGVL  206


>gi|254820951|ref|ZP_05225952.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium intracellulare 
ATCC 13950]
Length=210

 Score =  375 bits (963),  Expect = 2e-102, Method: Compositional matrix adjust.
 Identities = 192/210 (92%), Positives = 199/210 (95%), Gaps = 0/210 (0%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MT   T KA+RRAR+ERRT+ESDIVIELDLDGTGQV VDTGVPFYDHMLTALGSHASFDL
Sbjct  1    MTAVNTEKAARRARVERRTKESDIVIELDLDGTGQVDVDTGVPFYDHMLTALGSHASFDL  60

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TVR  GDVEIE HHTIEDTAIALG ALGQALGDKRGIRRFGDAFIPMDETLAHAAVD+SG
Sbjct  61   TVRTKGDVEIEGHHTIEDTAIALGQALGQALGDKRGIRRFGDAFIPMDETLAHAAVDVSG  120

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            RPYCVH+GEPDHLQHTTIAG+SVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITE
Sbjct  121  RPYCVHSGEPDHLQHTTIAGNSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITE  180

Query  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            A+YKAVARALRQAVEPDPRVSGVPSTKG L
Sbjct  181  AEYKAVARALRQAVEPDPRVSGVPSTKGVL  210


>gi|118617224|ref|YP_905556.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium ulcerans 
Agy99]
 gi|183982411|ref|YP_001850702.1| imidazole glycerol-phosphate dehydratase HisB [Mycobacterium 
marinum M]
 gi|166219786|sp|A0PP16.1|HIS7_MYCUA RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|238690950|sp|B2HQA4.1|HIS7_MYCMM RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|118569334|gb|ABL04085.1| imidazole glycerol-phosphate dehydratase HisB [Mycobacterium 
ulcerans Agy99]
 gi|183175737|gb|ACC40847.1| imidazole glycerol-phosphate dehydratase HisB [Mycobacterium 
marinum M]
Length=210

 Score =  372 bits (955),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 193/210 (92%), Positives = 200/210 (96%), Gaps = 0/210 (0%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MT T+T  A RRARIERRTRESDIVI+LDLDGTGQV VDTGVPF+DHMLTALGSHASFDL
Sbjct  1    MTATETGTAVRRARIERRTRESDIVIDLDLDGTGQVDVDTGVPFFDHMLTALGSHASFDL  60

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TVR  GDVEIEAHHT+EDTAIALG ALGQALGDK+GIRRFGDAFIPMDETLAHAAVD+SG
Sbjct  61   TVRTKGDVEIEAHHTVEDTAIALGQALGQALGDKKGIRRFGDAFIPMDETLAHAAVDVSG  120

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            RPYCVHTGEPDHLQHTTIAG+SVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITE
Sbjct  121  RPYCVHTGEPDHLQHTTIAGNSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITE  180

Query  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            AQYKAVARALRQAVEPDPRVSGVPSTKG L
Sbjct  181  AQYKAVARALRQAVEPDPRVSGVPSTKGVL  210


>gi|254775632|ref|ZP_05217148.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=207

 Score =  370 bits (949),  Expect = 9e-101, Method: Compositional matrix adjust.
 Identities = 181/192 (95%), Positives = 186/192 (97%), Gaps = 0/192 (0%)

Query  19   TRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIED  78
            T+ESDIVIELDLDGTG+V V+TGVPFYDHMLTALGSHASFDLTVR TGDVEIEAHHTIED
Sbjct  16   TKESDIVIELDLDGTGRVDVETGVPFYDHMLTALGSHASFDLTVRTTGDVEIEAHHTIED  75

Query  79   TAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTI  138
            TAIALG ALGQALGDKRGIRRFGDAFIPMDETLAHAAVD+SGRPYCVH+GEPDHLQHTTI
Sbjct  76   TAIALGAALGQALGDKRGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHSGEPDHLQHTTI  135

Query  139  AGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP  198
            AGSSVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP
Sbjct  136  AGSSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP  195

Query  199  RVSGVPSTKGAL  210
            RVS VPSTKG L
Sbjct  196  RVSDVPSTKGVL  207


>gi|15827645|ref|NP_301908.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium leprae 
TN]
 gi|221230122|ref|YP_002503538.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium leprae 
Br4923]
 gi|7387768|sp|Q9X7B9.1|HIS7_MYCLE RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|254801928|sp|B8ZRB1.1|HIS7_MYCLB RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|4883454|emb|CAB43168.1| putative imidazole glycerol-phosphate dehydratase [Mycobacterium 
leprae]
 gi|13093196|emb|CAC31640.1| imidazole glycerol-phosphate dehydratase [Mycobacterium leprae]
 gi|219933229|emb|CAR71354.1| imidazole glycerol-phosphate dehydratase [Mycobacterium leprae 
Br4923]
Length=210

 Score =  369 bits (948),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 179/210 (86%), Positives = 189/210 (90%), Gaps = 0/210 (0%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MT T+  K +RRARIERRT ESDIV+ELDLDGTGQV +DTGV FYDHMLTALGSHASFDL
Sbjct  1    MTNTEVGKTTRRARIERRTSESDIVVELDLDGTGQVHIDTGVSFYDHMLTALGSHASFDL  60

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TV   GDVEIEAHHTIEDTAIALG A GQALG+K+GIRRFGDAFIPMDETL HA VD+SG
Sbjct  61   TVCTKGDVEIEAHHTIEDTAIALGQAFGQALGNKKGIRRFGDAFIPMDETLVHAVVDVSG  120

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            RPYCVHTGEPDHLQH  I+GSSVPY TVINRHVFESLAANARIALHVRVLYGRDPHHITE
Sbjct  121  RPYCVHTGEPDHLQHNIISGSSVPYSTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180

Query  181  AQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            AQYKAVARAL +AV+ DPR SGVPSTKG L
Sbjct  181  AQYKAVARALSEAVKFDPRFSGVPSTKGVL  210


>gi|41407393|ref|NP_960229.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium avium 
subsp. paratuberculosis K-10]
 gi|118464037|ref|YP_882368.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium avium 
104]
 gi|46395663|sp|P60886.1|HIS7_MYCPA RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|166219781|sp|A0QHI0.1|HIS7_MYCA1 RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|41395745|gb|AAS03612.1| HisB [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118165324|gb|ABK66221.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium avium 
104]
 gi|336457881|gb|EGO36874.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=207

 Score =  369 bits (947),  Expect = 2e-100, Method: Compositional matrix adjust.
 Identities = 180/192 (94%), Positives = 186/192 (97%), Gaps = 0/192 (0%)

Query  19   TRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIED  78
            T+ESDIVIELDLDGTG+V V+TGVPFYDHMLTALGSHASFDLTVR TGDVEIEAHHTIED
Sbjct  16   TKESDIVIELDLDGTGRVDVETGVPFYDHMLTALGSHASFDLTVRTTGDVEIEAHHTIED  75

Query  79   TAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTI  138
            TAIALG ALGQALGDKRGIRRFGDAFIPMDETLAHAAVD+SGRPYCVH+GEPDHLQH+TI
Sbjct  76   TAIALGAALGQALGDKRGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHSGEPDHLQHSTI  135

Query  139  AGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP  198
            AGSSVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP
Sbjct  136  AGSSVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDP  195

Query  199  RVSGVPSTKGAL  210
            RVS VPSTKG L
Sbjct  196  RVSDVPSTKGVL  207


>gi|169629753|ref|YP_001703402.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium abscessus 
ATCC 19977]
 gi|169241720|emb|CAM62748.1| Imidazole glycerol-phosphate dehydratase [Mycobacterium abscessus]
Length=207

 Score =  361 bits (926),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 172/201 (86%), Positives = 186/201 (93%), Gaps = 0/201 (0%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            +R AR+ R TRESDIV+EL+LDG+GQV +DTGVPFYDHMLTALG+HASFDLT+ A GD E
Sbjct  7    ARTARVARATRESDIVVELNLDGSGQVQIDTGVPFYDHMLTALGTHASFDLTITAKGDTE  66

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            IEAHHT+EDTAI LG AL +ALGDK+GIRRFGDAFIPMDETLAHA VD+SGRPYCVHTGE
Sbjct  67   IEAHHTVEDTAITLGQALAEALGDKKGIRRFGDAFIPMDETLAHAVVDVSGRPYCVHTGE  126

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            PDHL HTTIAGSSVPYHTVIN HVFESLA NARIALHVR LYGRDPHHITEAQYKAVARA
Sbjct  127  PDHLLHTTIAGSSVPYHTVINAHVFESLALNARIALHVRTLYGRDPHHITEAQYKAVARA  186

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LRQAVEPDPRV+GVPSTKG+L
Sbjct  187  LRQAVEPDPRVTGVPSTKGSL  207


>gi|240167973|ref|ZP_04746632.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium kansasii 
ATCC 12478]
Length=210

 Score =  359 bits (922),  Expect = 1e-97, Method: Compositional matrix adjust.
 Identities = 175/189 (93%), Positives = 180/189 (96%), Gaps = 0/189 (0%)

Query  22   SDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAI  81
            SDIV+ELDLDGTGQV VDTGVPFYDHMLTALGSHASFDLTVR TGDV IEAHH++EDTAI
Sbjct  22   SDIVVELDLDGTGQVDVDTGVPFYDHMLTALGSHASFDLTVRTTGDVHIEAHHSVEDTAI  81

Query  82   ALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGS  141
            ALG ALGQALGDK+GIRRFGDAFIPMDE LAHAAVD+SGRPYCVHTGEPDHLQHTTIAGS
Sbjct  82   ALGQALGQALGDKKGIRRFGDAFIPMDEALAHAAVDVSGRPYCVHTGEPDHLQHTTIAGS  141

Query  142  SVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVS  201
            SVPYHTVINRHVFESLA NARIALHVRVLYGRDPHHITEAQYKAVARALRQAV PDPR S
Sbjct  142  SVPYHTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVAPDPRTS  201

Query  202  GVPSTKGAL  210
            GVPSTKG L
Sbjct  202  GVPSTKGVL  210


>gi|333990785|ref|YP_004523399.1| imidazole glycerol-phosphate dehydratase [Mycobacterium sp. JDM601]
 gi|333486753|gb|AEF36145.1| imidazole glycerol-phosphate dehydratase HisB [Mycobacterium 
sp. JDM601]
Length=204

 Score =  358 bits (919),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 172/190 (91%), Positives = 182/190 (96%), Gaps = 0/190 (0%)

Query  21   ESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTA  80
            ESDIV+ELDLDGTG V +DTGVPFYDHMLTALGSHASFDLTVRA GD+EIEAHHT+EDTA
Sbjct  15   ESDIVVELDLDGTGVVDIDTGVPFYDHMLTALGSHASFDLTVRAKGDIEIEAHHTVEDTA  74

Query  81   IALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAG  140
            I LG ALGQALGDK+GIRRFGDAFIPMDETLAHAAVD+SGRPYCVHTGEPDHL HTTIAG
Sbjct  75   IVLGQALGQALGDKKGIRRFGDAFIPMDETLAHAAVDVSGRPYCVHTGEPDHLVHTTIAG  134

Query  141  SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRV  200
            +  PYHTVINRHVFE+LA+NARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRV
Sbjct  135  TQAPYHTVINRHVFETLASNARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRV  194

Query  201  SGVPSTKGAL  210
            +GVPSTKGAL
Sbjct  195  TGVPSTKGAL  204


>gi|120403790|ref|YP_953619.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium vanbaalenii 
PYR-1]
 gi|166219787|sp|A1T8W3.1|HIS7_MYCVP RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|119956608|gb|ABM13613.1| Imidazoleglycerol-phosphate dehydratase [Mycobacterium vanbaalenii 
PYR-1]
Length=208

 Score =  357 bits (917),  Expect = 5e-97, Method: Compositional matrix adjust.
 Identities = 169/203 (84%), Positives = 189/203 (94%), Gaps = 0/203 (0%)

Query  8    KASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGD  67
            + +RRA++ER+T+ESDIV+ELDLDGTGQV+VDTGVPF+DHMLT+LGSHASFDLT++A GD
Sbjct  6    RPARRAKVERKTKESDIVVELDLDGTGQVSVDTGVPFFDHMLTSLGSHASFDLTIKAVGD  65

Query  68   VEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHT  127
            +EIE HHTIEDTAI LG ALGQALGDK+GIRRFGDAFIPMDETLAHAAVD+SGRPY VHT
Sbjct  66   IEIEGHHTIEDTAIVLGQALGQALGDKKGIRRFGDAFIPMDETLAHAAVDVSGRPYFVHT  125

Query  128  GEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            GEPD++   TIAGS+ PYHTV+NRHVFESLA NARIALHVR LYGRDPHHITEA+YKAVA
Sbjct  126  GEPDYMVEFTIAGSAAPYHTVVNRHVFESLAFNARIALHVRTLYGRDPHHITEAEYKAVA  185

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALRQAVE DPRVSGVPSTKG L
Sbjct  186  RALRQAVEYDPRVSGVPSTKGTL  208


>gi|108800027|ref|YP_640224.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium sp. MCS]
 gi|119869152|ref|YP_939104.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium sp. KMS]
 gi|126435656|ref|YP_001071347.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium sp. JLS]
 6 more sequence titles
 Length=208

 Score =  350 bits (899),  Expect = 6e-95, Method: Compositional matrix adjust.
 Identities = 169/207 (82%), Positives = 187/207 (91%), Gaps = 0/207 (0%)

Query  4    TQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVR  63
            T     +RRAR+ER+T+ESDIV++LDLDGTG V + TGVPF+DHMLT+LGSHASFDLTV 
Sbjct  2    TDMLTGTRRARVERKTKESDIVVDLDLDGTGIVDIRTGVPFFDHMLTSLGSHASFDLTVH  61

Query  64   ATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPY  123
            ATGD+EIE HHT+EDTAI LG ALGQALGDK+GIRRFGDAFIPMDETLAHAAVD+SGRPY
Sbjct  62   ATGDIEIEGHHTVEDTAIVLGQALGQALGDKKGIRRFGDAFIPMDETLAHAAVDVSGRPY  121

Query  124  CVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQY  183
             VHTGEPD++   TIAGSS PYHTVINRHVFESLA NARIALHVR +YGRDPHHITEAQY
Sbjct  122  FVHTGEPDYMVEFTIAGSSAPYHTVINRHVFESLAFNARIALHVRTIYGRDPHHITEAQY  181

Query  184  KAVARALRQAVEPDPRVSGVPSTKGAL  210
            KAVARALRQAVE DPRV+GVPSTKG+L
Sbjct  182  KAVARALRQAVELDPRVTGVPSTKGSL  208


>gi|145224195|ref|YP_001134873.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium gilvum 
PYR-GCK]
 gi|315444529|ref|YP_004077408.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium sp. Spyr1]
 gi|189043486|sp|A4T9M6.1|HIS7_MYCGI RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|145216681|gb|ABP46085.1| Imidazoleglycerol-phosphate dehydratase [Mycobacterium gilvum 
PYR-GCK]
 gi|315262832|gb|ADT99573.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium sp. Spyr1]
Length=202

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 164/201 (82%), Positives = 185/201 (93%), Gaps = 0/201 (0%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SR A++ER+T+ESDIV+ELDLDGTGQV++DTGVPF+DHMLT+LG+HASFDLTV+A GD+E
Sbjct  2    SRFAKVERKTKESDIVVELDLDGTGQVSIDTGVPFFDHMLTSLGTHASFDLTVKAVGDIE  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            IE HHTIEDT+I LG AL QALGDK+GIRRFGDAFIPMDE LAHAAVD+SGRPY VHTGE
Sbjct  62   IEGHHTIEDTSIVLGQALAQALGDKKGIRRFGDAFIPMDECLAHAAVDVSGRPYFVHTGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            PD++   TIAGS+ PYHTV+NRHVFESLA NARIALHVR LYGRDPHHITEA+YKAVARA
Sbjct  122  PDYMVQFTIAGSAAPYHTVVNRHVFESLAYNARIALHVRTLYGRDPHHITEAEYKAVARA  181

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LRQAVE DPRV+GVPSTKG L
Sbjct  182  LRQAVEYDPRVTGVPSTKGTL  202


>gi|118473296|ref|YP_887521.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium smegmatis 
str. MC2 155]
 gi|189043487|sp|A0QX83.1|HIS7_MYCS2 RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|118174583|gb|ABK75479.1| imidazoleglycerol-phosphate dehydratase [Mycobacterium smegmatis 
str. MC2 155]
Length=206

 Score =  343 bits (880),  Expect = 9e-93, Method: Compositional matrix adjust.
 Identities = 165/206 (81%), Positives = 185/206 (90%), Gaps = 0/206 (0%)

Query  5    QTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRA  64
             +A A+RRAR+ER+T+ES+IV++LDLDGTG V +DTGVPF+DHMLT+LGSHASFDLTV A
Sbjct  1    MSALANRRARVERKTKESEIVVDLDLDGTGVVDIDTGVPFFDHMLTSLGSHASFDLTVHA  60

Query  65   TGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYC  124
             GD+EIE HHT+EDTAI LG ALGQALGDK+GIRRFGDAFIPMDE+LAHAAVD+SGRPY 
Sbjct  61   KGDIEIEGHHTVEDTAIVLGQALGQALGDKKGIRRFGDAFIPMDESLAHAAVDVSGRPYF  120

Query  125  VHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYK  184
            VHTGEP+ +   TIAG+  PYHTVINRHVFESLA NARIALHVR LYGRDPHHITEAQYK
Sbjct  121  VHTGEPESMVSFTIAGTGAPYHTVINRHVFESLAFNARIALHVRTLYGRDPHHITEAQYK  180

Query  185  AVARALRQAVEPDPRVSGVPSTKGAL  210
            AVARALRQAVE D RV+GVPSTKG L
Sbjct  181  AVARALRQAVEYDARVTGVPSTKGTL  206


>gi|325674476|ref|ZP_08154164.1| histidine biosynthesis bifunctional protein HisB (histidinol-phosphatase/imidazoleglycerol-phosphate 
dehydratase) [Rhodococcus 
equi ATCC 33707]
 gi|325554736|gb|EGD24410.1| histidine biosynthesis bifunctional protein HisB (histidinol-phosphatase/imidazoleglycerol-phosphate 
dehydratase) [Rhodococcus 
equi ATCC 33707]
Length=204

 Score =  342 bits (877),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 164/203 (81%), Positives = 184/203 (91%), Gaps = 1/203 (0%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            + R AR+ER T+ES IV+EL+LDGTG V+V TG+PF+DHMLTALG+HASFDLTV A GDV
Sbjct  2    SERIARVERTTKESSIVVELNLDGTGNVSVSTGIPFFDHMLTALGAHASFDLTVEAKGDV  61

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
            EI+AHHT+EDTAI LG ALGQALGDKRGIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTG
Sbjct  62   EIDAHHTVEDTAIVLGQALGQALGDKRGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTG  121

Query  129  EPDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            EP+H+ H+ I G   VPY TVINRHVFES+A NARIALHVRVLYGRD HHITEA++KAVA
Sbjct  122  EPEHMLHSVIGGYPGVPYSTVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVA  181

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALR+AVEPDPRVSGVPSTKGAL
Sbjct  182  RALREAVEPDPRVSGVPSTKGAL  204


>gi|312140047|ref|YP_004007383.1| imidazole glycerol-phosphate dehydratase hisb [Rhodococcus equi 
103S]
 gi|311889386|emb|CBH48702.1| imidazole glycerol-phosphate dehydratase HisB [Rhodococcus equi 
103S]
Length=204

 Score =  342 bits (876),  Expect = 3e-92, Method: Compositional matrix adjust.
 Identities = 164/203 (81%), Positives = 184/203 (91%), Gaps = 1/203 (0%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            + R AR+ER T+ES IV+EL+LDGTG V+V TG+PF+DHMLTALG+HASFDLTV A GDV
Sbjct  2    SDRIARVERTTKESSIVVELNLDGTGNVSVSTGIPFFDHMLTALGAHASFDLTVEAKGDV  61

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
            EI+AHHT+EDTAI LG ALGQALGDKRGIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTG
Sbjct  62   EIDAHHTVEDTAIVLGQALGQALGDKRGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTG  121

Query  129  EPDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            EP+H+ H+ I G   VPY TVINRHVFES+A NARIALHVRVLYGRD HHITEA++KAVA
Sbjct  122  EPEHMLHSVIGGYPGVPYSTVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVA  181

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALR+AVEPDPRVSGVPSTKGAL
Sbjct  182  RALREAVEPDPRVSGVPSTKGAL  204


>gi|226306937|ref|YP_002766897.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus erythropolis 
PR4]
 gi|229491047|ref|ZP_04384878.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus erythropolis 
SK121]
 gi|259709896|sp|C1A0M3.1|HIS7_RHOE4 RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|226186054|dbj|BAH34158.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus erythropolis 
PR4]
 gi|229322028|gb|EEN87818.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus erythropolis 
SK121]
Length=204

 Score =  336 bits (861),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 163/203 (81%), Positives = 180/203 (89%), Gaps = 1/203 (0%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            + R ARIER TRES IV+EL+LDGTG V V TGVPF+DHML ALG+HASFDL V+A GDV
Sbjct  2    SDRIARIERTTRESSIVVELNLDGTGIVDVSTGVPFFDHMLNALGTHASFDLDVKAKGDV  61

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
            EI+AHHT+EDTAI  G ALGQALGDK+GIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTG
Sbjct  62   EIDAHHTVEDTAIVFGQALGQALGDKKGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTG  121

Query  129  EPDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            EPD++ H+ I G   VPYH VINRHVFES+A NARIALHVRVLYGRD HHITEA+YKAVA
Sbjct  122  EPDYMVHSVIGGYPGVPYHAVINRHVFESIALNARIALHVRVLYGRDQHHITEAEYKAVA  181

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALR+AVEPDPRVSGVPSTKG L
Sbjct  182  RALREAVEPDPRVSGVPSTKGTL  204


>gi|111018042|ref|YP_701014.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus jostii RHA1]
 gi|123046638|sp|Q0SHY0.1|HIS7_RHOSR RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|110817572|gb|ABG92856.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus jostii RHA1]
Length=204

 Score =  335 bits (859),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 162/201 (81%), Positives = 181/201 (91%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R AR+ER T+ES I +EL+LDGTG V V TGVPF+DHMLTALGSHASFDLTV A GD+EI
Sbjct  4    RIARVERTTKESSITVELNLDGTGIVDVSTGVPFFDHMLTALGSHASFDLTVHAKGDIEI  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            EAHHT+EDT+I LG ALGQALGDK+GIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTGEP
Sbjct  64   EAHHTVEDTSIVLGQALGQALGDKKGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTGEP  123

Query  131  DHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            +HL H+ I G   VPY TVINRHVFES+A NARIALHVRVLYGRD HHITEA++KAVARA
Sbjct  124  EHLLHSVIGGYPGVPYATVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVARA  183

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR+AVEPDPRV+GVPSTKG+L
Sbjct  184  LREAVEPDPRVTGVPSTKGSL  204


>gi|226360169|ref|YP_002777947.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus opacus B4]
 gi|254801932|sp|C1ATZ4.1|HIS7_RHOOB RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|226238654|dbj|BAH49002.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus opacus B4]
Length=204

 Score =  334 bits (857),  Expect = 5e-90, Method: Compositional matrix adjust.
 Identities = 162/201 (81%), Positives = 180/201 (90%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R AR+ER T+ES I +EL+LDGTG V V TGVPF+DHMLTALGSHASFDLTV A GD+EI
Sbjct  4    RIARVERTTKESSITVELNLDGTGIVDVSTGVPFFDHMLTALGSHASFDLTVHAKGDIEI  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            EAHHT+EDT+I LG ALGQALGDK+GIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTGEP
Sbjct  64   EAHHTVEDTSIVLGQALGQALGDKKGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTGEP  123

Query  131  DHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            +HL H  I G   VPY TVINRHVFES+A NARIALHVRVLYGRD HHITEA++KAVARA
Sbjct  124  EHLLHAVIGGYPGVPYATVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVARA  183

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR+AVEPDPRV+GVPSTKG+L
Sbjct  184  LREAVEPDPRVTGVPSTKGSL  204


>gi|171850953|emb|CAQ00039.1| imidazoleglycerol-phosphate dehydratase [Rhodococcus erythropolis]
Length=204

 Score =  334 bits (856),  Expect = 6e-90, Method: Compositional matrix adjust.
 Identities = 162/203 (80%), Positives = 179/203 (89%), Gaps = 1/203 (0%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            + R ARIER TRES IV+EL+LDGTG V V TGVPF+DHML ALG+HASFDL V+A GDV
Sbjct  2    SDRIARIERTTRESSIVVELNLDGTGIVDVSTGVPFFDHMLNALGTHASFDLDVKAKGDV  61

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
            EI+AHHT+EDTAI  G ALGQAL DK+GIRRFGDAFIPMDETLAHA+VD+SGRPYCVHTG
Sbjct  62   EIDAHHTVEDTAIVFGQALGQALSDKKGIRRFGDAFIPMDETLAHASVDVSGRPYCVHTG  121

Query  129  EPDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            EPD++ H+ I G   VPYH VINRHVFES+A NARIALHVRVLYGRD HHITEA+YKAVA
Sbjct  122  EPDYMVHSVIGGYPGVPYHAVINRHVFESIALNARIALHVRVLYGRDQHHITEAEYKAVA  181

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALR+AVEPDPRVSGVPSTKG L
Sbjct  182  RALREAVEPDPRVSGVPSTKGTL  204


>gi|343926605|ref|ZP_08766104.1| imidazoleglycerol-phosphate dehydratase [Gordonia alkanivorans 
NBRC 16433]
 gi|343763475|dbj|GAA13030.1| imidazoleglycerol-phosphate dehydratase [Gordonia alkanivorans 
NBRC 16433]
Length=207

 Score =  312 bits (799),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 152/203 (75%), Positives = 169/203 (84%), Gaps = 1/203 (0%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            A R A++ER T+ES I +EL+LDGTG   + TG+ FYDHMLTA G H SFDLTV+A GD+
Sbjct  5    APRIAKVERTTKESSISVELNLDGTGITDISTGIAFYDHMLTAFGQHGSFDLTVKAEGDI  64

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
            E+E HHTIEDTAI LG ALGQALGDKRGIRRFGDA+IPMDETLA A VD+SGRPYCVHTG
Sbjct  65   EVEGHHTIEDTAIVLGQALGQALGDKRGIRRFGDAWIPMDETLAQAVVDVSGRPYCVHTG  124

Query  129  EPDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            EP+HL    I G   VPY T+INRHVFES+A NARIALHVRVLYGRD HHITEA++KAVA
Sbjct  125  EPEHLLTAVIGGYPGVPYSTIINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVA  184

Query  188  RALRQAVEPDPRVSGVPSTKGAL  210
            RALR A E D RVSGVPSTKGAL
Sbjct  185  RALRTATEYDARVSGVPSTKGAL  207


>gi|54023815|ref|YP_118057.1| imidazoleglycerol-phosphate dehydratase [Nocardia farcinica IFM 
10152]
 gi|59797668|sp|Q5YYP8.1|HIS7_NOCFA RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|54015323|dbj|BAD56693.1| putative imidazoleglycerol-phosphate dehydratase [Nocardia farcinica 
IFM 10152]
Length=216

 Score =  309 bits (792),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 162/215 (76%), Positives = 180/215 (84%), Gaps = 8/215 (3%)

Query  4    TQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVR  63
            T T    R AR+ER T+ES IV+ELDLDGTG+  + TGVPFYDHMLTALG+HASFDL+VR
Sbjct  2    TDTTLRHRTARVERVTKESSIVVELDLDGTGRTDISTGVPFYDHMLTALGAHASFDLSVR  61

Query  64   ATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPY  123
            A GD++IEAHHT+EDTAI  G ALG+ALGDK GIRRFGDAFIPMDETLAHAAVD+SGRPY
Sbjct  62   AEGDIQIEAHHTVEDTAIVFGQALGKALGDKAGIRRFGDAFIPMDETLAHAAVDVSGRPY  121

Query  124  CVHTGEPDHLQHTTIAGSSV--------PYHTVINRHVFESLAANARIALHVRVLYGRDP  175
            CVHTGEP+HL H  I GS V        PY TV+NRHVFES+A NARIALHVRVLYGRD 
Sbjct  122  CVHTGEPEHLLHAVIPGSPVRGTGEPGAPYSTVLNRHVFESIALNARIALHVRVLYGRDQ  181

Query  176  HHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
            HH+TEA++KAVARALR AVE DPRVSGVPSTKG L
Sbjct  182  HHVTEAEFKAVARALRAAVEFDPRVSGVPSTKGTL  216


>gi|296139733|ref|YP_003646976.1| imidazoleglycerol-phosphate dehydratase [Tsukamurella paurometabola 
DSM 20162]
 gi|296027867|gb|ADG78637.1| Imidazoleglycerol-phosphate dehydratase [Tsukamurella paurometabola 
DSM 20162]
Length=204

 Score =  307 bits (787),  Expect = 6e-82, Method: Compositional matrix adjust.
 Identities = 158/201 (79%), Positives = 175/201 (88%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R ARIER TRES IV+EL+LDG G   + TGVPF+DHMLTA G H SFDL V+A GDVEI
Sbjct  4    RIARIERTTRESAIVVELNLDGNGTTEIATGVPFFDHMLTAFGQHGSFDLAVQAKGDVEI  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            +AHHT+EDTAI LG A+G+ALGDK+GIRRFGD FIPMDETLAHA+VD+SGRPY VHTGEP
Sbjct  64   DAHHTVEDTAIVLGQAIGEALGDKKGIRRFGDCFIPMDETLAHASVDVSGRPYAVHTGEP  123

Query  131  DHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            ++L H+ I G   VPY TVINRHVFESLA NARIALHVRVLYGRDPHHITEA+YKAVARA
Sbjct  124  EYLVHSVIGGYPGVPYSTVINRHVFESLAMNARIALHVRVLYGRDPHHITEAEYKAVARA  183

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR AVEPDPRVSGVPSTKG+L
Sbjct  184  LRAAVEPDPRVSGVPSTKGSL  204


>gi|296394238|ref|YP_003659122.1| imidazoleglycerol-phosphate dehydratase [Segniliparus rotundus 
DSM 44985]
 gi|296181385|gb|ADG98291.1| Imidazoleglycerol-phosphate dehydratase [Segniliparus rotundus 
DSM 44985]
Length=205

 Score =  306 bits (783),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 150/204 (74%), Positives = 172/204 (85%), Gaps = 1/204 (0%)

Query  8    KASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGD  67
             A+R+ARIER T+E+ +++E+ LDG+G   V TGVPFYDHMLTA G+H  FDLTV A GD
Sbjct  2    SATRQARIERATKETKVLVEIGLDGSGATDVATGVPFYDHMLTAFGAHGGFDLTVHAEGD  61

Query  68   VEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHT  127
            VEIEAHHT+EDTAI LG A+ QALGDK GI RFGDA++PMDE+LAHAAVD+SGRPY VH 
Sbjct  62   VEIEAHHTVEDTAICLGQAIRQALGDKAGITRFGDAWVPMDESLAHAAVDVSGRPYFVHA  121

Query  128  GEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVA  187
            GEP  L+  TIAGSSVPYHTV+NRHVFESL+ NA+IALHVRV++GRDPHHITEAQYKAVA
Sbjct  122  GEPQGLETFTIAGSSVPYHTVMNRHVFESLSCNAQIALHVRVVHGRDPHHITEAQYKAVA  181

Query  188  RALRQAVEPDPRVSG-VPSTKGAL  210
            RALR AV  DPR  G VPSTKG L
Sbjct  182  RALRHAVALDPRTQGRVPSTKGVL  205


>gi|258653327|ref|YP_003202483.1| imidazoleglycerol-phosphate dehydratase [Nakamurella multipartita 
DSM 44233]
 gi|258556552|gb|ACV79494.1| Imidazoleglycerol-phosphate dehydratase [Nakamurella multipartita 
DSM 44233]
Length=199

 Score =  305 bits (781),  Expect = 3e-81, Method: Compositional matrix adjust.
 Identities = 147/201 (74%), Positives = 172/201 (86%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SRRARIER T ES ++++LDLDGTGQV + TGV FYDHML + G H SFDLTVR+ GDV+
Sbjct  2    SRRARIERTTSESSVLVDLDLDGTGQVEISTGVRFYDHMLISFGVHGSFDLTVRSVGDVD  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+AHHT+EDTAI LG A+GQA+GDK+GIRRFGDAF+PMDETLAHAAVDLSGRPY VH GE
Sbjct  62   IDAHHTVEDTAIVLGQAIGQAVGDKKGIRRFGDAFVPMDETLAHAAVDLSGRPYSVHLGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P+++    + G++ P   V+N HVF+SLA +AR+ LHVRVLYGRDPHHI EAQYKA+ARA
Sbjct  122  PENI-FGAVVGNNYP--VVLNTHVFDSLAFHARMNLHVRVLYGRDPHHICEAQYKAIARA  178

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LRQAVEPDPRVSGVPSTKG L
Sbjct  179  LRQAVEPDPRVSGVPSTKGVL  199


>gi|333919111|ref|YP_004492692.1| Imidazoleglycerol-phosphate dehydratase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333481332|gb|AEF39892.1| Imidazoleglycerol-phosphate dehydratase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=204

 Score =  305 bits (780),  Expect = 3e-81, Method: Compositional matrix adjust.
 Identities = 157/201 (79%), Positives = 172/201 (86%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R AR+ER TRES I +E++LDGTGQV V TGVPF+DHMLTALG H SFDLTV+A GD+EI
Sbjct  4    RIARVERTTRESSITVEINLDGTGQVEVATGVPFFDHMLTALGVHGSFDLTVQAQGDIEI  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            EAHHT+EDTAI LG A GQALGDK+GIRRF DA IPMDETLA A VD+SGRPYCVHTGEP
Sbjct  64   EAHHTVEDTAIVLGQAFGQALGDKKGIRRFADACIPMDETLAQAIVDVSGRPYCVHTGEP  123

Query  131  DHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            +H+  T I G    PY TVINRHVFES A NARIALHVRVLYGRDPHHITEA++KAVARA
Sbjct  124  EHMLTTIIGGYPGTPYATVINRHVFESFALNARIALHVRVLYGRDPHHITEAEFKAVARA  183

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR AVEPDPRV G+PSTKGAL
Sbjct  184  LRAAVEPDPRVGGIPSTKGAL  204


>gi|319950576|ref|ZP_08024485.1| imidazoleglycerol-phosphate dehydratase [Dietzia cinnamea P4]
 gi|319435770|gb|EFV90981.1| imidazoleglycerol-phosphate dehydratase [Dietzia cinnamea P4]
Length=207

 Score =  304 bits (778),  Expect = 6e-81, Method: Compositional matrix adjust.
 Identities = 155/202 (77%), Positives = 173/202 (86%), Gaps = 1/202 (0%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            +RRAR+ER T+ES IV+E+DLDGTGQ  + TGVPF+DHMLTA G H +FDLTVRATGD+E
Sbjct  6    ARRARVERTTKESSIVVEIDLDGTGQTDISTGVPFFDHMLTAFGQHGAFDLTVRATGDIE  65

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            IEAHHT+EDTAI LG A GQALGDKRGIRRFG   IPMDETLA A VD+SGRPYCVHTGE
Sbjct  66   IEAHHTVEDTAIVLGQAFGQALGDKRGIRRFGQCSIPMDETLAEAVVDVSGRPYCVHTGE  125

Query  130  PDHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVAR  188
            PD +    I G  S PY TV+NRHVFE+LA NARIALHVRV YGRDPHHITEA+YKAVAR
Sbjct  126  PDMMLGYLIVGHDSAPYGTVLNRHVFETLAYNARIALHVRVHYGRDPHHITEAEYKAVAR  185

Query  189  ALRQAVEPDPRVSGVPSTKGAL  210
            ALR AVEPDPR++G+PSTKGAL
Sbjct  186  ALRAAVEPDPRITGIPSTKGAL  207


>gi|262202851|ref|YP_003274059.1| imidazoleglycerol-phosphate dehydratase [Gordonia bronchialis 
DSM 43247]
 gi|262086198|gb|ACY22166.1| Imidazoleglycerol-phosphate dehydratase [Gordonia bronchialis 
DSM 43247]
Length=204

 Score =  304 bits (778),  Expect = 7e-81, Method: Compositional matrix adjust.
 Identities = 147/201 (74%), Positives = 165/201 (83%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R A++ER T+ES I +EL+LDGTG   + TG+ F+DHML A G H SFDL V A GDVE+
Sbjct  4    RIAKVERTTKESSISVELNLDGTGVTDISTGIAFFDHMLGAFGQHGSFDLRVHAKGDVEV  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            E HHTIEDTAI LG ALGQALGDK+GIRRFGDA+IPMDETLA A VD+SGRPYCVH+GEP
Sbjct  64   EGHHTIEDTAIVLGQALGQALGDKKGIRRFGDAWIPMDETLAQAVVDVSGRPYCVHSGEP  123

Query  131  DHLQHTTIAG-SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            DH+    I G   VPY TVINRHVFES+A NARIALHVRVLYGRD HHITEA++KAVARA
Sbjct  124  DHMLSAVIGGYPGVPYSTVINRHVFESIALNARIALHVRVLYGRDQHHITEAEFKAVARA  183

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR A E D RVSGVPSTKG+L
Sbjct  184  LRAATESDARVSGVPSTKGSL  204


>gi|326382624|ref|ZP_08204315.1| imidazoleglycerol-phosphate dehydratase [Gordonia neofelifaecis 
NRRL B-59395]
 gi|326198743|gb|EGD55926.1| imidazoleglycerol-phosphate dehydratase [Gordonia neofelifaecis 
NRRL B-59395]
Length=212

 Score =  300 bits (768),  Expect = 8e-80, Method: Compositional matrix adjust.
 Identities = 157/216 (73%), Positives = 176/216 (82%), Gaps = 10/216 (4%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MTT Q     R ARIER TRES IV+E+DLDGTG+  +DT VPF+DHMLTA G+H SFDL
Sbjct  1    MTTAQ----HRTARIERTTRESSIVVEIDLDGTGKTDIDTSVPFFDHMLTAFGAHGSFDL  56

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
            TV A GD+EIEAHHT+EDT I LG A+G+ALGDK+GIRRFGDA+IPMDETLA A VD+SG
Sbjct  57   TVHAKGDIEIEAHHTVEDTCIVLGQAIGEALGDKKGIRRFGDAWIPMDETLAQAIVDVSG  116

Query  121  RPYCVHTGEPDHLQHTTIAGSS------VPYHTVINRHVFESLAANARIALHVRVLYGRD  174
            RPYCVHTGEPDH+    I G S      V Y TV+NRH FES+A NARIALHVRVLYGRD
Sbjct  117  RPYCVHTGEPDHMLTAVIGGYSGGAKPVVSYATVLNRHAFESIALNARIALHVRVLYGRD  176

Query  175  PHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL  210
             HHITEA++KAVARALR AVEPDPR SG+PSTKGAL
Sbjct  177  QHHITEAEFKAVARALRAAVEPDPRTSGIPSTKGAL  212


>gi|256379721|ref|YP_003103381.1| imidazoleglycerol-phosphate dehydratase [Actinosynnema mirum 
DSM 43827]
 gi|255924024|gb|ACU39535.1| Imidazoleglycerol-phosphate dehydratase [Actinosynnema mirum 
DSM 43827]
Length=200

 Score =  297 bits (761),  Expect = 6e-79, Method: Compositional matrix adjust.
 Identities = 146/202 (73%), Positives = 167/202 (83%), Gaps = 4/202 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SR  R+ER TRES +++E+DLDGTGQV +DT VPFY+HML ALG+H S DL V+ATGD +
Sbjct  2    SRVGRVERATRESSVLVEVDLDGTGQVEIDTSVPFYNHMLNALGTHGSLDLVVKATGDTD  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+AHHT+EDTAI LG AL QALGDK+GIRRFGD +IPMDETLAHAAVD+SGRPYCVHTGE
Sbjct  62   IDAHHTVEDTAIVLGQALRQALGDKKGIRRFGDCWIPMDETLAHAAVDVSGRPYCVHTGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P      TI G+   Y  V+NRHVF+SLA +A IALHVRV YGRDPHHI EAQYKA+ RA
Sbjct  122  PAEFNAFTIGGN---YPFVLNRHVFDSLAFHAGIALHVRVEYGRDPHHIAEAQYKAIGRA  178

Query  190  LRQAVEPDPRVSG-VPSTKGAL  210
            LR AVEPDPRV+G VPSTKG L
Sbjct  179  LRAAVEPDPRVAGVVPSTKGVL  200


>gi|317508559|ref|ZP_07966221.1| imidazoleglycerol-phosphate dehydratase [Segniliparus rugosus 
ATCC BAA-974]
 gi|316253142|gb|EFV12550.1| imidazoleglycerol-phosphate dehydratase [Segniliparus rugosus 
ATCC BAA-974]
Length=204

 Score =  296 bits (758),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 146/201 (73%), Positives = 168/201 (84%), Gaps = 1/201 (0%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            RRARIER T+E+ +++E+ LDG+G   + TGVPFYDHMLTA G+H  FDLTV A GDVEI
Sbjct  4    RRARIERATKETKVLVEIALDGSGATDIATGVPFYDHMLTAFGAHGGFDLTVHAEGDVEI  63

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            EAHHT+ED AI LG A+ QALGDK GI RFGDA++PMDE LAHAAVD+SGRPY V  GEP
Sbjct  64   EAHHTVEDVAICLGQAIRQALGDKAGITRFGDAWVPMDEALAHAAVDVSGRPYFVQVGEP  123

Query  131  DHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARAL  190
            + +   TIAGSSVPYHTVINRHVFESL+ +A+IALHVRV++GRDPHHITEA+YKAVARAL
Sbjct  124  EGMATFTIAGSSVPYHTVINRHVFESLSFHAQIALHVRVVHGRDPHHITEAEYKAVARAL  183

Query  191  RQAVEPDPRVSG-VPSTKGAL  210
            RQAV  DPR  G VPSTKG L
Sbjct  184  RQAVALDPRALGKVPSTKGVL  204


>gi|302525411|ref|ZP_07277753.1| imidazoleglycerol-phosphate dehydratase [Streptomyces sp. AA4]
 gi|302434306|gb|EFL06122.1| imidazoleglycerol-phosphate dehydratase [Streptomyces sp. AA4]
Length=199

 Score =  295 bits (754),  Expect = 4e-78, Method: Compositional matrix adjust.
 Identities = 143/201 (72%), Positives = 167/201 (84%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SR  ++ER T+ES I+++LDLDGTGQV + TGVPFYDHMLTA G H S DL V ATGDV 
Sbjct  2    SRVGKVERTTKESSILVQLDLDGTGQVEIATGVPFYDHMLTAFGVHGSLDLKVEATGDVH  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+AHHT+EDTAI LG AL QALGDK GIRRFGDA+IPMDETLAHAA+D+SGRPYCVH GE
Sbjct  62   IDAHHTVEDTAIVLGQALRQALGDKSGIRRFGDAWIPMDETLAHAAIDVSGRPYCVHVGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P+     TI G++ P+  V+ RHVF+SLA +A+IALHVRV++GRDPHHI EA+YKAVARA
Sbjct  122  PEQFNTFTI-GNNYPF--VLTRHVFDSLAFHAQIALHVRVIHGRDPHHIAEAEYKAVARA  178

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR A EPDPRV G+PSTKG L
Sbjct  179  LRAATEPDPRVGGIPSTKGVL  199


>gi|134102225|ref|YP_001107886.1| imidazoleglycerol-phosphate dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|291003813|ref|ZP_06561786.1| imidazoleglycerol-phosphate dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|166219805|sp|A4FLN6.1|HIS7_SACEN RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|133914848|emb|CAM04961.1| imidazoleglycerol-phosphate dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
Length=206

 Score =  293 bits (750),  Expect = 1e-77, Method: Compositional matrix adjust.
 Identities = 147/211 (70%), Positives = 172/211 (82%), Gaps = 6/211 (2%)

Query  1    MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDL  60
            MT  Q    +R  R+ER TRES +++ELDLDGTGQV +DT VPFYDHMLTALG+HA+FDL
Sbjct  1    MTAMQ--PGTRVGRVERTTRESSVLVELDLDGTGQVDIDTTVPFYDHMLTALGTHAAFDL  58

Query  61   TVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSG  120
             V+++GDV I+AHHT+EDTAI  G AL QALG K GIRRFGDA+IPMDETLAHAAVD+SG
Sbjct  59   KVKSSGDVHIDAHHTVEDTAIVFGQALRQALGGKLGIRRFGDAWIPMDETLAHAAVDVSG  118

Query  121  RPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE  180
            R YCV TGEP+     TI G+   Y  V+NRHVFES+A +++I LHVRV++GRDPHHI E
Sbjct  119  RSYCVMTGEPEQYNSFTIGGN---YPFVLNRHVFESIAFHSQINLHVRVIHGRDPHHIAE  175

Query  181  AQYKAVARALRQAVEPDPRVSG-VPSTKGAL  210
            AQYKA+ARALR AVEPDPR SG VPSTKGAL
Sbjct  176  AQYKAIARALRAAVEPDPRFSGVVPSTKGAL  206


>gi|257055140|ref|YP_003132972.1| imidazoleglycerol-phosphate dehydratase [Saccharomonospora viridis 
DSM 43017]
 gi|256585012|gb|ACU96145.1| imidazoleglycerol-phosphate dehydratase [Saccharomonospora viridis 
DSM 43017]
Length=199

 Score =  292 bits (747),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 141/201 (71%), Positives = 163/201 (82%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SR  ++ER T+ES I +ELDLDG+GQV V TGVPFYDHML + G H S DL + A GDV 
Sbjct  2    SRVGKVERTTKESSIRVELDLDGSGQVEVSTGVPFYDHMLHSFGVHGSLDLRIEAQGDVH  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+AHHT+EDTAI LG AL QALGDK+GIRRFGDA+IPMDETLAHAA+D+SGRPYCVH GE
Sbjct  62   IDAHHTVEDTAIVLGQALRQALGDKKGIRRFGDAWIPMDETLAHAAIDVSGRPYCVHVGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P+     TI G+   Y  V+ RHVFESL+ +A+IALHVRVL+GRDPHHI EAQYKAVARA
Sbjct  122  PEQFNTFTIGGN---YPFVLTRHVFESLSFHAQIALHVRVLHGRDPHHIAEAQYKAVARA  178

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR+A EPDPR  G+PSTKG L
Sbjct  179  LREATEPDPRAGGIPSTKGVL  199


>gi|300784163|ref|YP_003764454.1| imidazoleglycerol-phosphate dehydratase [Amycolatopsis mediterranei 
U32]
 gi|299793677|gb|ADJ44052.1| imidazoleglycerol-phosphate dehydratase [Amycolatopsis mediterranei 
U32]
 gi|340525580|gb|AEK40785.1| imidazoleglycerol-phosphate dehydratase [Amycolatopsis mediterranei 
S699]
Length=199

 Score =  290 bits (743),  Expect = 7e-77, Method: Compositional matrix adjust.
 Identities = 140/201 (70%), Positives = 163/201 (82%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            +R  ++ER T+ES I ++LDLDGTG+V + TGVPFYDHMLTA G H S DL V ATGDV 
Sbjct  2    TRIGKVERTTKESSIFVQLDLDGTGEVDISTGVPFYDHMLTAFGVHGSLDLKVEATGDVH  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+AHHT+EDTAI LG A+ QALGDK GIRRFGDA+IPMDETLAHAAVD+SGRPYCVH GE
Sbjct  62   IDAHHTVEDTAIVLGQAIRQALGDKSGIRRFGDAWIPMDETLAHAAVDVSGRPYCVHVGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P+     TI G+   Y  V+ RHVF+SLA +A+IALHVRV++GRDPHHI EA+YKAVARA
Sbjct  122  PEQFNSFTIGGN---YPFVLTRHVFDSLAFHAQIALHVRVIHGRDPHHIAEAEYKAVARA  178

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR A EPDPR  G+PSTKG L
Sbjct  179  LRAATEPDPRAGGIPSTKGVL  199


>gi|340794168|ref|YP_004759631.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium variabile 
DSM 44702]
 gi|340534078|gb|AEK36558.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium variabile 
DSM 44702]
Length=204

 Score =  290 bits (741),  Expect = 1e-76, Method: Compositional matrix adjust.
 Identities = 141/205 (69%), Positives = 165/205 (81%), Gaps = 3/205 (1%)

Query  6    TAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRAT  65
            T +A R ARIER T+ES I +E++LDGTG   +DT +PF+DHMLTA G+H SFDLTV A 
Sbjct  3    TPRADRIARIERTTKESAITVEINLDGTGTTDIDTKLPFFDHMLTAFGAHGSFDLTVHAD  62

Query  66   GDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCV  125
            GD+E++AHHT+EDTAI LG A  QALGDK+GIRRF D++IPMDETLA A VD+SGRPY V
Sbjct  63   GDIEVDAHHTVEDTAIVLGQAFAQALGDKKGIRRFADSYIPMDETLAQAVVDVSGRPYYV  122

Query  126  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  185
             TGEP+ +  T I G    Y TVIN+H FE+LA NARIALHVR LYGRDPHHITEA++KA
Sbjct  123  GTGEPETMLTTVIGGH---YATVINQHFFETLAFNARIALHVRCLYGRDPHHITEAEFKA  179

Query  186  VARALRQAVEPDPRVSGVPSTKGAL  210
            VARALR A E DPRV+GVPSTKG L
Sbjct  180  VARALRAATESDPRVTGVPSTKGTL  204


>gi|336325385|ref|YP_004605351.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium resistens 
DSM 45100]
 gi|336101367|gb|AEI09187.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium resistens 
DSM 45100]
Length=200

 Score =  285 bits (729),  Expect = 3e-75, Method: Compositional matrix adjust.
 Identities = 139/194 (72%), Positives = 159/194 (82%), Gaps = 3/194 (1%)

Query  17   RRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTI  76
            R T ESDI +E +LDG+G+  + TG+PF+DHMLTALG+H SFDL V A GDVEI+AHHT+
Sbjct  10   RTTSESDITVEWNLDGSGKTDIQTGLPFFDHMLTALGAHGSFDLKVYAKGDVEIDAHHTV  69

Query  77   EDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHT  136
            EDTAI +G AL +ALG+K GIRRFGDAFIPMDE LAHAAVD+SGRPY V TGEP+ +   
Sbjct  70   EDTAIVMGQALNEALGNKAGIRRFGDAFIPMDECLAHAAVDVSGRPYYVGTGEPETMVTA  129

Query  137  TIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEP  196
             I G    Y TVIN+H FESLA NARIALHVR LYGRDPHHITEA++KAVARALR AVE 
Sbjct  130  VIGGH---YATVINQHFFESLAFNARIALHVRCLYGRDPHHITEAEFKAVARALRLAVEA  186

Query  197  DPRVSGVPSTKGAL  210
            DPR SG+PSTKGAL
Sbjct  187  DPRTSGIPSTKGAL  200


>gi|334563076|ref|ZP_08516067.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium bovis 
DSM 20582]
Length=206

 Score =  283 bits (725),  Expect = 9e-75, Method: Compositional matrix adjust.
 Identities = 141/190 (75%), Positives = 156/190 (83%), Gaps = 3/190 (1%)

Query  21   ESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTA  80
            ESDI + +DLDGTG   +DTGVPF+DHMLTA G+H +FDLTV ATGD  I+AHHT+EDTA
Sbjct  20   ESDISVTIDLDGTGVTDIDTGVPFFDHMLTAFGAHGAFDLTVHATGDTHIDAHHTVEDTA  79

Query  81   IALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAG  140
            I LG A G+ALGDK GIRRFGDAF+PMDE LAHAAVD+SGRPY V TGEPD L  T I G
Sbjct  80   IVLGGAFGEALGDKAGIRRFGDAFVPMDEALAHAAVDVSGRPYHVSTGEPDTLLTTVIGG  139

Query  141  SSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRV  200
                Y TVINRH FE+LA NARIALHVR LYGRDPHHITEA++KA ARALR AVEPD RV
Sbjct  140  H---YATVINRHFFETLALNARIALHVRCLYGRDPHHITEAEFKATARALRAAVEPDGRV  196

Query  201  SGVPSTKGAL  210
            +GVPSTKG L
Sbjct  197  TGVPSTKGTL  206


>gi|237785383|ref|YP_002906088.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium kroppenstedtii 
DSM 44385]
 gi|237758295|gb|ACR17545.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium kroppenstedtii 
DSM 44385]
Length=218

 Score =  283 bits (723),  Expect = 2e-74, Method: Compositional matrix adjust.
 Identities = 136/201 (68%), Positives = 163/201 (82%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            +RR   ER T+ES I ++++LDG+G   + TG+PF+DHML A+G+H SFDLTVRA GD++
Sbjct  21   ARRGHCERETKESRITVDINLDGSGITDISTGLPFFDHMLNAVGTHGSFDLTVRAEGDID  80

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            ++AHHT+EDTAI +G AL +ALGDK GIRRFG +FIPMDETLA A VD+SGRPYCV  GE
Sbjct  81   VDAHHTVEDTAIVMGEALHEALGDKAGIRRFGSSFIPMDETLAQAVVDVSGRPYCVTRGE  140

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P  + +T I      Y TVIN+H FESLA +ARIALHVRVLYGRDPHHITEA+YKAVARA
Sbjct  141  PQEMMNTVIGNH---YATVINQHFFESLAFHARIALHVRVLYGRDPHHITEAEYKAVARA  197

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR+AVE D RV GVPSTKGAL
Sbjct  198  LREAVERDSRVHGVPSTKGAL  218


>gi|300780880|ref|ZP_07090734.1| histidine biosynthesis bifunctional protein HisB (histidinol-phosphatase/imidazoleglycerol-phosphate 
dehydratase) [Corynebacterium 
genitalium ATCC 33030]
 gi|300532587|gb|EFK53648.1| histidine biosynthesis bifunctional protein HisB (histidinol-phosphatase/imidazoleglycerol-phosphate 
dehydratase) [Corynebacterium 
genitalium ATCC 33030]
Length=200

 Score =  276 bits (705),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 135/194 (70%), Positives = 154/194 (80%), Gaps = 3/194 (1%)

Query  17   RRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTI  76
            R T ESDI +E++LDGTG V VDTG+PF+DHMLTA G+H SFDLT++A GD+EI+AHHTI
Sbjct  10   RTTSESDISVEINLDGTGNVDVDTGLPFFDHMLTAFGTHGSFDLTIKARGDIEIDAHHTI  69

Query  77   EDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHT  136
            EDTAI LG AL  A+GDK+GIRRFG   +PMDETL  A VD+S RPY V  GEP+ ++  
Sbjct  70   EDTAITLGWALIDAVGDKKGIRRFGSMALPMDETLVSAVVDISNRPYFVMNGEPESMEWQ  129

Query  137  TIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEP  196
             I G    Y TVINRH FE+LA NARI LHV V YGRDPHHITEA+YKAVARALR A E 
Sbjct  130  IIGGH---YATVINRHFFETLAYNARITLHVNVEYGRDPHHITEAEYKAVARALRAAYEI  186

Query  197  DPRVSGVPSTKGAL  210
            DPRVSGVPSTKGAL
Sbjct  187  DPRVSGVPSTKGAL  200


>gi|68535863|ref|YP_250568.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium jeikeium 
K411]
 gi|123651185|sp|Q4JW57.1|HIS7_CORJK RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|68263462|emb|CAI36950.1| hisB [Corynebacterium jeikeium K411]
Length=204

 Score =  275 bits (704),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 144/205 (71%), Positives = 165/205 (81%), Gaps = 3/205 (1%)

Query  6    TAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRAT  65
            T    R  + +R T+ESDI +E +LDGTG+  +DTGVPF+DHMLTALG+H SFDL V A 
Sbjct  3    TNPTPRIGKAQRATKESDIQVEWNLDGTGKTDIDTGVPFFDHMLTALGAHGSFDLKVHAR  62

Query  66   GDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCV  125
            GDVEI+AHHT+EDTAI +G AL QALGDK GIRRFGDAFIPMDETLAHAAVD+SGRPY V
Sbjct  63   GDVEIDAHHTVEDTAIVMGQALAQALGDKAGIRRFGDAFIPMDETLAHAAVDVSGRPYYV  122

Query  126  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  185
              GEP+ +  + I G    Y TVIN+H FE+LA N+RIALHVR LYGRDPHHITEA++KA
Sbjct  123  GVGEPEQMLSSVIGGH---YATVINQHFFETLALNSRIALHVRCLYGRDPHHITEAEFKA  179

Query  186  VARALRQAVEPDPRVSGVPSTKGAL  210
            VARALR AVE DPRV GVPSTKG L
Sbjct  180  VARALRAAVEDDPRVGGVPSTKGTL  204


>gi|172040854|ref|YP_001800568.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium urealyticum 
DSM 7109]
 gi|238065370|sp|B1VH93.1|HIS7_CORU7 RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|171852158|emb|CAQ05134.1| unnamed protein product [Corynebacterium urealyticum DSM 7109]
Length=204

 Score =  275 bits (704),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 143/200 (72%), Positives = 165/200 (83%), Gaps = 3/200 (1%)

Query  11   RRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEI  70
            R  R +R+T ESDI + ++LDG+G+  + TG+PF+DHMLTALG+H SFDL V+A GDVEI
Sbjct  8    RIGRAQRKTSESDISVSINLDGSGKTDISTGLPFFDHMLTALGAHGSFDLEVKAVGDVEI  67

Query  71   EAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEP  130
            +AHHT+EDT I LG ALG+ALG K GIRRFGDAFIPMDE LAHAAVD+SGRPY V TGEP
Sbjct  68   DAHHTVEDTGIVLGQALGEALGTKAGIRRFGDAFIPMDECLAHAAVDVSGRPYYVGTGEP  127

Query  131  DHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARAL  190
            D + HT I G    Y TVIN+H FE+LA NARIALHVR LYGRDPHHITEA+YKAVARAL
Sbjct  128  DAMVHTVIGGH---YATVINQHFFETLALNARIALHVRCLYGRDPHHITEAEYKAVARAL  184

Query  191  RQAVEPDPRVSGVPSTKGAL  210
            R AVE D RV+G+PSTKGAL
Sbjct  185  RAAVERDERVTGIPSTKGAL  204


>gi|260578045|ref|ZP_05845967.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium jeikeium 
ATCC 43734]
 gi|258603785|gb|EEW17040.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium jeikeium 
ATCC 43734]
Length=204

 Score =  275 bits (702),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 144/205 (71%), Positives = 164/205 (80%), Gaps = 3/205 (1%)

Query  6    TAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRAT  65
            T    R  + +R T+ESDI +E +LDGTG+  +DTGVPF+DHMLTALG+H SFDL V A 
Sbjct  3    TNPTPRIGKAQRATKESDIQVEWNLDGTGKTDIDTGVPFFDHMLTALGAHGSFDLKVHAR  62

Query  66   GDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCV  125
            GDVEI+AHHT+EDTAI +G AL QALGDK GIRRFGDAFIPMDETLAHAAVD+SGRPY V
Sbjct  63   GDVEIDAHHTVEDTAIVMGQALAQALGDKAGIRRFGDAFIPMDETLAHAAVDVSGRPYYV  122

Query  126  HTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKA  185
              GEP+ +    I G    Y TVIN+H FE+LA N+RIALHVR LYGRDPHHITEA++KA
Sbjct  123  GVGEPEQMLSAVIGGH---YATVINQHFFETLALNSRIALHVRCLYGRDPHHITEAEFKA  179

Query  186  VARALRQAVEPDPRVSGVPSTKGAL  210
            VARALR AVE DPRV GVPSTKG L
Sbjct  180  VARALRAAVEDDPRVGGVPSTKGTL  204


>gi|152967119|ref|YP_001362903.1| imidazoleglycerol-phosphate dehydratase [Kineococcus radiotolerans 
SRS30216]
 gi|189043478|sp|A6WCV0.1|HIS7_KINRD RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD
 gi|151361636|gb|ABS04639.1| Imidazoleglycerol-phosphate dehydratase [Kineococcus radiotolerans 
SRS30216]
Length=199

 Score =  273 bits (698),  Expect = 1e-71, Method: Compositional matrix adjust.
 Identities = 134/201 (67%), Positives = 157/201 (79%), Gaps = 3/201 (1%)

Query  10   SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE  69
            SR ARIER T ES +++ELDLDGTG+ ++DT VPFYDHMLTALG H+  DLTV A GD  
Sbjct  2    SRTARIERSTSESSVLVELDLDGTGRTSIDTTVPFYDHMLTALGKHSLMDLTVVAKGDTH  61

Query  70   IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGE  129
            I+ HHT+EDTAI LG A  QALGDK GIRRF DA +P+DE LAH  VD+SGRPYCVHTGE
Sbjct  62   IDVHHTVEDTAIVLGQAFRQALGDKAGIRRFADATVPLDEALAHVVVDVSGRPYCVHTGE  121

Query  130  PDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARA  189
            P+  ++  I G    +   + RH+ ES A +ARIALHVRVL GRDPHH+ EAQ+KA+ARA
Sbjct  122  PEGQEYHLIGGH---FTGSLTRHLLESFAFHARIALHVRVLAGRDPHHVVEAQFKALARA  178

Query  190  LRQAVEPDPRVSGVPSTKGAL  210
            LR AVEPDPRV G+PSTKGAL
Sbjct  179  LRYAVEPDPRVQGIPSTKGAL  199


>gi|300858780|ref|YP_003783763.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium pseudotuberculosis 
FRC41]
 gi|300686234|gb|ADK29156.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium pseudotuberculosis 
FRC41]
 gi|302206485|gb|ADL10827.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium pseudotuberculosis 
C231]
 gi|302331040|gb|ADL21234.1| Imidazoleglycerol-phosphate dehydratase [Corynebacterium pseudotuberculosis 
1002]
Length=202

 Score =  271 bits (692),  Expect = 6e-71, Method: Compositional matrix adjust.
 Identities = 134/204 (66%), Positives = 153/204 (75%), Gaps = 3/204 (1%)

Query  7    AKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATG  66
            A ASR   + R T ES+I + +DLDG+G V V+TGVPF DHMLTA G H +FDLTV ATG
Sbjct  2    AAASRIGTVTRTTSESNITVTIDLDGSGHVDVNTGVPFLDHMLTAFGVHGAFDLTVSATG  61

Query  67   DVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVH  126
            D  I+AHHT+EDTAI LG AL  A+GDKRGIRRFG   +PMDETL  A VD SGRPY V 
Sbjct  62   DTHIDAHHTVEDTAIVLGQALRAAVGDKRGIRRFGSFQLPMDETLCEAVVDFSGRPYFVM  121

Query  127  TGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAV  186
             GEPD++ H  + G    Y TVINRH FESLA NA I LHV   YGRDPHHITEA++KAV
Sbjct  122  NGEPDYMAHFVVGGH---YPTVINRHFFESLALNAAITLHVNCRYGRDPHHITEAEFKAV  178

Query  187  ARALRQAVEPDPRVSGVPSTKGAL  210
            ARA+R A EPDPR+ G+PSTKGAL
Sbjct  179  ARAIRHATEPDPRLQGIPSTKGAL  202


>gi|213965232|ref|ZP_03393429.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium amycolatum 
SK46]
 gi|213952084|gb|EEB63469.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium amycolatum 
SK46]
Length=212

 Score =  270 bits (691),  Expect = 8e-71, Method: Compositional matrix adjust.
 Identities = 140/206 (68%), Positives = 158/206 (77%), Gaps = 3/206 (1%)

Query  5    QTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRA  64
            +  +  R  R+ER TRES IV  ++LDGTG+  + TG+PF+DHMLTA GSH SFDLTV A
Sbjct  10   EAERTERVGRVERATRESSIVCSVNLDGTGKTDISTGLPFFDHMLTAFGSHGSFDLTVHA  69

Query  65   TGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYC  124
             GD E++AHHT+EDT I +G A  QALGDK GIRRFGD +IPMDETLAHA VD+SGRPY 
Sbjct  70   NGDTEVDAHHTVEDTGIVMGQAFAQALGDKSGIRRFGDCYIPMDETLAHAVVDVSGRPYF  129

Query  125  VHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYK  184
            V TGEP+ +    I G    Y TVIN H FES A NARIALHVR LYGRDPHHITEA+YK
Sbjct  130  VGTGEPEQMLTAVIGGH---YATVINEHFFESFALNARIALHVRCLYGRDPHHITEAEYK  186

Query  185  AVARALRQAVEPDPRVSGVPSTKGAL  210
            AVARALR AVE DPRV GVPSTKG L
Sbjct  187  AVARALRAAVEDDPRVHGVPSTKGTL  212


>gi|227548953|ref|ZP_03979002.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium lipophiloflavum 
DSM 44291]
 gi|227078978|gb|EEI16941.1| imidazoleglycerol-phosphate dehydratase [Corynebacterium lipophiloflavum 
DSM 44291]
Length=200

 Score =  269 bits (688),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 130/202 (65%), Positives = 152/202 (76%), Gaps = 3/202 (1%)

Query  9    ASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDV  68
            + R     R T ESDI +E++LDGTG+  + TG+PF+DHMLTA G+H +FDL + A GD 
Sbjct  2    SQRLGSASRTTSESDITVEINLDGTGKTDIFTGLPFFDHMLTAFGTHGAFDLAINAKGDT  61

Query  69   EIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTG  128
             I+AHHT+EDTAI LG AL  A+GDK GIRRFG A +PMDETL  + VD SGRPY V  G
Sbjct  62   HIDAHHTVEDTAITLGWALADAVGDKAGIRRFGSALLPMDETLVESVVDFSGRPYFVMDG  121

Query  129  EPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVAR  188
            EPDHLQ   I G    Y TVINRH FE+LAANAR+ LH+ V YGRDPHHITEA+YKAVA 
Sbjct  122  EPDHLQWQIIGGH---YATVINRHFFETLAANARVTLHINVRYGRDPHHITEAEYKAVAH  178

Query  189  ALRQAVEPDPRVSGVPSTKGAL  210
            ALRQA E D R++GVPSTKGAL
Sbjct  179  ALRQATELDGRITGVPSTKGAL  200


>gi|325000028|ref|ZP_08121140.1| imidazoleglycerol-phosphate dehydratase [Pseudonocardia sp. P1]
Length=196

 Score =  269 bits (687),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 132/198 (67%), Positives = 157/198 (80%), Gaps = 3/198 (1%)

Query  13   ARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEA  72
             R+ER T+E+ I +E+DLDGTG+  +DT VPFYDHML A G H SFDL+V A GD EI+A
Sbjct  2    GRVERVTKETRITVEIDLDGTGRTEIDTKVPFYDHMLDAFGKHGSFDLSVHADGDTEIDA  61

Query  73   HHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDH  132
            HHT+ED AI LG A+ QALGDK GIRRFGDA+IPMDE LA A VD+SGRPY V TGEP+ 
Sbjct  62   HHTVEDVAIVLGQAIRQALGDKTGIRRFGDAWIPMDEALAQAVVDVSGRPYTVCTGEPEM  121

Query  133  LQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQ  192
            ++   + G    Y TV+N+HVFESLA +  +ALHVRV+ GRDPHHITEA++KAVARALR 
Sbjct  122  MRGFVVGGH---YPTVLNKHVFESLAFHGHLALHVRVIDGRDPHHITEAEFKAVARALRA  178

Query  193  AVEPDPRVSGVPSTKGAL  210
            A E DPRV+GVPSTKGAL
Sbjct  179  ATEADPRVTGVPSTKGAL  196



Lambda     K      H
   0.319    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 245963417238


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40