BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1607 Length=360 Score E Sequences producing significant alignments: (Bits) Value gi|15608745|ref|NP_216123.1| ionic transporter integral membrane... 677 0.0 gi|340626613|ref|YP_004745065.1| putative ionic transporter inte... 676 0.0 gi|342860822|ref|ZP_08717472.1| calcium/proton exchanger [Mycoba... 510 1e-142 gi|183982423|ref|YP_001850714.1| ionic transporter integral memb... 493 2e-137 gi|240167980|ref|ZP_04746639.1| ionic transporter integral membr... 477 1e-132 gi|15827650|ref|NP_301913.1| antiporter [Mycobacterium leprae TN... 471 8e-131 gi|254820957|ref|ZP_05225958.1| calcium/proton exchanger [Mycoba... 468 5e-130 gi|41407399|ref|NP_960235.1| ChaA [Mycobacterium avium subsp. pa... 468 8e-130 gi|336457887|gb|EGO36880.1| Ca2+/H+ antiporter [Mycobacterium av... 467 1e-129 gi|296164474|ref|ZP_06847046.1| calcium/proton antiporter membra... 461 6e-128 gi|84497995|ref|ZP_00996792.1| Probable ionic transporter integr... 445 6e-123 gi|256377804|ref|YP_003101464.1| sodium/calcium exchanger membra... 426 2e-117 gi|21220447|ref|NP_626226.1| ionic transporter [Streptomyces coe... 417 2e-114 gi|300786409|ref|YP_003766700.1| Ca2+/H+ antiporter [Amycolatops... 412 6e-113 gi|294628744|ref|ZP_06707304.1| cation/proton antiporter [Strept... 409 3e-112 gi|226359807|ref|YP_002777585.1| Ca(2+)/H(+) antiporter [Rhodoco... 407 2e-111 gi|297196373|ref|ZP_06913771.1| ionic transporter integral membr... 405 4e-111 gi|311894269|dbj|BAJ26677.1| putative calcium/proton antiporter ... 404 9e-111 gi|297198913|ref|ZP_06916310.1| ionic transporter integral membr... 403 3e-110 gi|290961298|ref|YP_003492480.1| ion exchange transporter [Strep... 401 8e-110 gi|294811001|ref|ZP_06769644.1| ionic transporter [Streptomyces ... 400 3e-109 gi|302526422|ref|ZP_07278764.1| ionic transporter integral membr... 399 4e-109 gi|50955406|ref|YP_062694.1| calcium/proton antiporter [Leifsoni... 395 5e-108 gi|302550662|ref|ZP_07303004.1| ionic transporter integral membr... 395 7e-108 gi|302532824|ref|ZP_07285166.1| ionic transporter integral membr... 394 8e-108 gi|291440306|ref|ZP_06579696.1| ionic transporter [Streptomyces ... 389 3e-106 gi|326331324|ref|ZP_08197616.1| cation/proton antiporter [Nocard... 385 5e-105 gi|297626041|ref|YP_003687804.1| ionic transporter integral memb... 384 2e-104 gi|88856655|ref|ZP_01131311.1| Probable ionic transporter integr... 383 3e-104 gi|309811248|ref|ZP_07705039.1| putative calcium/proton exchange... 382 4e-104 gi|111017285|ref|YP_700257.1| sodium calcium/ proton antiporter ... 378 7e-103 gi|330468539|ref|YP_004406282.1| sodium/calcium exchanger membra... 378 7e-103 gi|238064521|ref|ZP_04609230.1| ionic transporter integral membr... 377 1e-102 gi|329940830|ref|ZP_08290110.1| ionic transporter [Streptomyces ... 377 1e-102 gi|29832819|ref|NP_827453.1| ionic transporter integral membrane... 377 1e-102 gi|344997893|ref|YP_004800747.1| sodium/calcium exchanger membra... 376 3e-102 gi|302561247|ref|ZP_07313589.1| cation/proton antiporter [Strept... 372 6e-101 gi|302870373|ref|YP_003839010.1| sodium/calcium exchanger membra... 370 2e-100 gi|328880344|emb|CCA53583.1| Calcium or proton antiporter [Strep... 364 1e-98 gi|54023079|ref|YP_117321.1| putative transporter [Nocardia farc... 355 9e-96 gi|284034771|ref|YP_003384702.1| sodium/calcium exchanger membra... 353 2e-95 gi|315498735|ref|YP_004087539.1| sodium/calcium exchanger membra... 338 1e-90 gi|256395890|ref|YP_003117454.1| sodium/calcium exchanger membra... 327 2e-87 gi|167584319|ref|ZP_02376707.1| sodium/calcium exchanger membran... 325 6e-87 gi|170702752|ref|ZP_02893610.1| sodium/calcium exchanger membran... 321 1e-85 gi|53717047|ref|YP_105842.1| calcium/proton exchanger [Burkholde... 314 1e-83 gi|167906382|ref|ZP_02493587.1| calcium/proton exchanger [Burkho... 314 2e-83 gi|126443857|ref|YP_001062487.1| calcium/proton exchanger [Burkh... 314 2e-83 gi|167819605|ref|ZP_02451285.1| calcium/proton exchanger [Burkho... 313 2e-83 gi|167742439|ref|ZP_02415213.1| calcium/proton exchanger [Burkho... 313 2e-83 >gi|15608745|ref|NP_216123.1| ionic transporter integral membrane protein chaA [Mycobacterium tuberculosis H37Rv] gi|15841060|ref|NP_336097.1| cation/proton antiporter [Mycobacterium tuberculosis CDC1551] gi|31792793|ref|NP_855286.1| ionic transporter integral membrane protein chaA [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=360 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/360 (100%), Positives = 360/360 (100%), Gaps = 0/360 (0%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP Sbjct 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY Sbjct 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF Sbjct 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 Query 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE Sbjct 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA Sbjct 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP Sbjct 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 >gi|340626613|ref|YP_004745065.1| putative ionic transporter integral membrane protein chaA [Mycobacterium canettii CIPT 140010059] gi|340004803|emb|CCC43947.1| putative ionic transporter integral membrane protein chaA [Mycobacterium canettii CIPT 140010059] Length=360 Score = 676 bits (1745), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/360 (99%), Positives = 359/360 (99%), Gaps = 0/360 (0%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP Sbjct 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY Sbjct 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF Sbjct 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 Query 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVAL AVVGLAKVESPVIEE Sbjct 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALAAVVGLAKVESPVIEE 240 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA Sbjct 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP Sbjct 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 >gi|342860822|ref|ZP_08717472.1| calcium/proton exchanger [Mycobacterium colombiense CECT 3035] gi|342131846|gb|EGT85103.1| calcium/proton exchanger [Mycobacterium colombiense CECT 3035] Length=363 Score = 510 bits (1313), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 281/363 (78%), Positives = 311/363 (86%), Gaps = 3/363 (0%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 M K + W VV+P L+ V L L WG+ +GPV+ LAA+ L GAV+AAV+HAEVVA RVGEP Sbjct 1 MSKWLSWNVVVPVLSVVVLALIWGETLGPVLVGLAALFLIGAVVAAVHHAEVVAHRVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLA AVT IEVALIV LM SGG++ ATLARDT FAA+MITTNGIAGLSLLLGS RY Sbjct 61 FGSLVLAAAVTVIEVALIVELMASGGNETATLARDTAFAALMITTNGIAGLSLLLGSRRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFN GSGAALATVTTLATLSLVLP FTT+ G E SPGQLIFA ASL LY++F+F Sbjct 121 GVTLFNAEGSGAALATVTTLATLSLVLPAFTTTAVGKEFSPGQLIFAAVASLLLYLVFVF 180 Query 181 TQTVRHRDFFLPVAQKGAVE---DDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPV 237 TQTVRHRDFFLPVAQKG D+SHADPP+TRAAL SLGL+L ALVAVVGLA+ ESP Sbjct 181 TQTVRHRDFFLPVAQKGQKSLFADESHADPPTTRAALTSLGLMLGALVAVVGLAEEESPA 240 Query 238 IEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIP 297 +E+ V+A GFPQSFVGV+IA LVLLPET+AA RAARQGR+Q SLNLAYGSAMASIGLTIP Sbjct 241 VEKAVTAVGFPQSFVGVIIAALVLLPETVAAVRAARQGRIQISLNLAYGSAMASIGLTIP 300 Query 298 TIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLA 357 IALAS+WL GPL LGLGAIQLVLL LTVV+SVLTVVPGRATRLQGEVHLVLLAAY+FLA Sbjct 301 AIALASIWLKGPLVLGLGAIQLVLLALTVVISVLTVVPGRATRLQGEVHLVLLAAYVFLA 360 Query 358 VVP 360 + P Sbjct 361 ISP 363 >gi|183982423|ref|YP_001850714.1| ionic transporter integral membrane protein ChaA [Mycobacterium marinum M] gi|183175749|gb|ACC40859.1| ionic transporter integral membrane protein ChaA [Mycobacterium marinum M] Length=360 Score = 493 bits (1270), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 310/360 (87%), Positives = 328/360 (92%), Gaps = 0/360 (0%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 M KR+ WTVV P LA VALVL+WG+ IGPVVGLL AVLLAGAVLAAV+HAEVVA RVGEP Sbjct 1 MWKRLSWTVVAPLLALVALVLSWGQHIGPVVGLLEAVLLAGAVLAAVHHAEVVAHRVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLAVAVT IEVALIV LM SGG AATLARDTVFAAVMITTNGIAGLSLLLGS RY Sbjct 61 FGSLVLAVAVTVIEVALIVTLMASGGHQAATLARDTVFAAVMITTNGIAGLSLLLGSQRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFN HGSG ALATVTTLATLSLVLPTFTTSQ GPE SPGQL FA ASL LY+LF+F Sbjct 121 GVTLFNAHGSGTALATVTTLATLSLVLPTFTTSQPGPEFSPGQLGFAAVASLALYLLFVF 180 Query 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 TQTVRHRDFFLPVAQKGAV+DD HADPPSTRAA+ SL LLLVALVAVVGLAK+ESP+IE Sbjct 181 TQTVRHRDFFLPVAQKGAVDDDRHADPPSTRAAMTSLALLLVALVAVVGLAKMESPIIER 240 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 +V AAGFPQSFVGV+IATLVLLPETLAA RAARQGRLQ SLNLAYGSAMASIGLTIPTIA Sbjct 241 MVVAAGFPQSFVGVIIATLVLLPETLAAGRAARQGRLQISLNLAYGSAMASIGLTIPTIA 300 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LAS+WLSGPL LGLGA+QLVLLVLTVVVS LTV+PGRATRLQGE+HLV+LAAY+FLAV P Sbjct 301 LASIWLSGPLLLGLGALQLVLLVLTVVVSALTVLPGRATRLQGELHLVVLAAYIFLAVSP 360 >gi|240167980|ref|ZP_04746639.1| ionic transporter integral membrane protein ChaA [Mycobacterium kansasii ATCC 12478] Length=360 Score = 477 bits (1227), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 303/360 (85%), Positives = 326/360 (91%), Gaps = 0/360 (0%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 M+KRVPW+VV P LAFVAL LTWG++IGP++GLL AVLLAGAVLAAV+HAEVVA RVGEP Sbjct 1 MVKRVPWSVVAPVLAFVALTLTWGQKIGPLLGLLEAVLLAGAVLAAVHHAEVVAHRVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLA+AVT IEVALIV LM SGG ATLARDTVFAAVMITTNGIAGL+LLLGS RY Sbjct 61 FGSLVLAIAVTVIEVALIVTLMASGGHQTATLARDTVFAAVMITTNGIAGLALLLGSRRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFN GSG+ALA VTTLATLSLVLPTFTTS+ GP+ SP QL FA ASLGLY+LF+F Sbjct 121 GVTLFNDQGSGSALAMVTTLATLSLVLPTFTTSKPGPQFSPSQLAFAAVASLGLYLLFVF 180 Query 181 TQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 TQTVRHRDFFLPVAQKGAV+DD HADPPSTR AL SLGLLL+ALVAVVGLAKVESP+IE Sbjct 181 TQTVRHRDFFLPVAQKGAVDDDRHADPPSTRVALRSLGLLLLALVAVVGLAKVESPIIER 240 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 ++AAGFP SF GVVIA LVLLPETLAAARAARQGRLQ SLNLAYGSAMASIGLTIPTIA Sbjct 241 AIAAAGFPPSFAGVVIAMLVLLPETLAAARAARQGRLQISLNLAYGSAMASIGLTIPTIA 300 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LASLWLSGPL LGLG QLVLLVLTV VS+LTVVPGRATRL+GEVHLVLLAAYLFL++VP Sbjct 301 LASLWLSGPLLLGLGPTQLVLLVLTVAVSMLTVVPGRATRLEGEVHLVLLAAYLFLSIVP 360 >gi|15827650|ref|NP_301913.1| antiporter [Mycobacterium leprae TN] gi|221230127|ref|YP_002503543.1| putative antiporter [Mycobacterium leprae Br4923] gi|4883459|emb|CAB43175.1| putative antiporter [Mycobacterium leprae] gi|13093201|emb|CAC31648.1| putative antiporter [Mycobacterium leprae] gi|219933234|emb|CAR71362.1| putative antiporter [Mycobacterium leprae Br4923] Length=364 Score = 471 bits (1212), Expect = 8e-131, Method: Compositional matrix adjust. Identities = 283/364 (78%), Positives = 315/364 (87%), Gaps = 4/364 (1%) Query 1 MLKRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 MLKR+ WT ++P A L LTWG++IGPVV L A LL GAVLAAV+HAEVVA RVGEP Sbjct 1 MLKRIAWTALVPLFALAVLALTWGREIGPVVTALQAALLTGAVLAAVHHAEVVAHRVGEP 60 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSLVLA AVT IEVALIV LM SG +++ TLARDT FAA+MITTNGIAG SLLLGS RY Sbjct 61 FGSLVLAAAVTVIEVALIVTLMASGENESWTLARDTAFAALMITTNGIAGFSLLLGSRRY 120 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GVTLFN HGSGAALAT+TTLATLSLVLPTFTTS G E SPGQL FA ASLGLY+LF+F Sbjct 121 GVTLFNAHGSGAALATLTTLATLSLVLPTFTTSHRGNEFSPGQLAFAAVASLGLYLLFVF 180 Query 181 TQTVRHRDFFLPVAQKGAV----EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESP 236 TQT+RHRDFFLPVAQKG ED+SHADPPS R+AL+SL LLLVAL+AVVGLA+++S Sbjct 181 TQTIRHRDFFLPVAQKGQKGLFEEDESHADPPSARSALISLALLLVALIAVVGLAELQSS 240 Query 237 VIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTI 296 IE +V+A GFPQ FVGVVIATLVLLPETLAA RAAR+GR+QTSLNLAYGSAMASIGLTI Sbjct 241 AIEHLVTAVGFPQPFVGVVIATLVLLPETLAAVRAARRGRIQTSLNLAYGSAMASIGLTI 300 Query 297 PTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFL 356 P IALAS+WL+GPL LGLGA QLVLL LTVV+SVLTVVPGRATRLQGEVHLVLLAA++FL Sbjct 301 PAIALASIWLTGPLILGLGATQLVLLALTVVISVLTVVPGRATRLQGEVHLVLLAAFVFL 360 Query 357 AVVP 360 A++P Sbjct 361 AIIP 364 >gi|254820957|ref|ZP_05225958.1| calcium/proton exchanger [Mycobacterium intracellulare ATCC 13950] Length=368 Score = 468 bits (1205), Expect = 5e-130, Method: Compositional matrix adjust. Identities = 259/341 (76%), Positives = 292/341 (86%), Gaps = 3/341 (0%) Query 23 WGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALM 82 WG+++GPV+ +AA+ L GAV+AAV+HAEVVA RVGEPFGSL+LA AVT IEVALIVALM Sbjct 28 WGEKLGPVLVAVAALFLVGAVVAAVHHAEVVAHRVGEPFGSLILAAAVTIIEVALIVALM 87 Query 83 VSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLAT 142 SGG++AATLARDT FAA+MITTNGIAGLSLLLGS RYGVTLFN G+GAALATVTT+AT Sbjct 88 TSGGNEAATLARDTAFAALMITTNGIAGLSLLLGSRRYGVTLFNAEGAGAALATVTTVAT 147 Query 143 LSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGA---V 199 LSLVLP FTT G E + QL FA A+L +Y+LF+FTQTVRHRDFFLP+AQ+G Sbjct 148 LSLVLPAFTTGHPGKEFTSSQLAFAAIATLLVYLLFVFTQTVRHRDFFLPIAQRGQKRVF 207 Query 200 EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATL 259 ED+SHADPPS R AL SL LLL ALVAVVGLA+ ESP +E V AG PQSFVGV+IA L Sbjct 208 EDESHADPPSRRQALSSLVLLLCALVAVVGLAEEESPAVEHAVMVAGLPQSFVGVIIAAL 267 Query 260 VLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQL 319 VLLPETLAAAR+AR+GR+Q SLNLAYGSAMASIGLTIPTIAL S+WL GPL LGLG IQL Sbjct 268 VLLPETLAAARSARKGRIQISLNLAYGSAMASIGLTIPTIALTSIWLKGPLVLGLGPIQL 327 Query 320 VLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 VLL LTVV+S+LTVVPGRATRLQGEVHLVLLAAY+FLA+ P Sbjct 328 VLLALTVVISMLTVVPGRATRLQGEVHLVLLAAYVFLAISP 368 >gi|41407399|ref|NP_960235.1| ChaA [Mycobacterium avium subsp. paratuberculosis K-10] gi|118464942|ref|YP_882362.1| calcium/proton exchanger [Mycobacterium avium 104] gi|254775626|ref|ZP_05217142.1| calcium/proton exchanger [Mycobacterium avium subsp. avium ATCC 25291] gi|41395751|gb|AAS03618.1| ChaA [Mycobacterium avium subsp. paratuberculosis K-10] gi|118166229|gb|ABK67126.1| calcium/proton exchanger [Mycobacterium avium 104] Length=368 Score = 468 bits (1203), Expect = 8e-130, Method: Compositional matrix adjust. Identities = 280/357 (79%), Positives = 309/357 (87%), Gaps = 3/357 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WTVV+P LA V L L WG+++GPV+ LAA+ L GAV+AAV+HAEVVA R+GEPFGSLVL Sbjct 12 WTVVVPVLAVVVLALIWGERLGPVLVALAALFLIGAVVAAVHHAEVVAHRIGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 A AVT IEVALIV LM SGG++ ATLARDT FAA+MITTNGIAGLSLLLGS RYGVTLFN Sbjct 72 AAAVTIIEVALIVELMASGGNETATLARDTAFAALMITTNGIAGLSLLLGSRRYGVTLFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 GSGAALAT+TTLATLSLVLP FTT+Q G E SPGQL FA ASL +Y+LF+FTQTVRH Sbjct 132 AEGSGAALATLTTLATLSLVLPAFTTTQVGKEFSPGQLTFAAVASLLVYLLFVFTQTVRH 191 Query 187 RDFFLPVAQKGA---VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 RDFFLP+AQKG ED+SHADPPSTR AL+SL LLL ALVAVVGLA+ ESP +E V+ Sbjct 192 RDFFLPIAQKGQKSLFEDESHADPPSTREALVSLVLLLCALVAVVGLAEEESPAVERAVT 251 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 A GFPQ+FVGV+IA LVLLPETLAA RAARQGR+Q SLNLAYGSAMASIGLTIP IALAS Sbjct 252 AVGFPQTFVGVIIAALVLLPETLAAVRAARQGRIQISLNLAYGSAMASIGLTIPAIALAS 311 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +WL GPL LGLGAIQLVLL LTVV+SVLTVVPGRATRLQGEVHLVLLAAY+FLAV P Sbjct 312 IWLKGPLVLGLGAIQLVLLALTVVISVLTVVPGRATRLQGEVHLVLLAAYVFLAVSP 368 >gi|336457887|gb|EGO36880.1| Ca2+/H+ antiporter [Mycobacterium avium subsp. paratuberculosis S397] Length=368 Score = 467 bits (1201), Expect = 1e-129, Method: Compositional matrix adjust. Identities = 270/341 (80%), Positives = 298/341 (88%), Gaps = 3/341 (0%) Query 23 WGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALM 82 WG+++GPV+ LAA+ L GAV+AAV+HAEVVA R+GEPFGSLVLA AVT IEVALIV LM Sbjct 28 WGERLGPVLVALAALFLIGAVVAAVHHAEVVAHRIGEPFGSLVLAAAVTIIEVALIVELM 87 Query 83 VSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLAT 142 SGG++ ATLARDT FAA+MITTNGIAGLSLLLGS RYGVTLFN GSGAALAT+TTLAT Sbjct 88 ASGGNETATLARDTAFAALMITTNGIAGLSLLLGSRRYGVTLFNAEGSGAALATLTTLAT 147 Query 143 LSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGA---V 199 LSLVLP FTT+Q G E SPGQL FA ASL +Y+LF+FTQTVRHRDFFLP+AQKG Sbjct 148 LSLVLPAFTTTQVGKEFSPGQLTFAAVASLLVYLLFVFTQTVRHRDFFLPIAQKGQKSLF 207 Query 200 EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATL 259 ED+SHADPPSTR AL+SL LLL ALVAVVGLA+ ESP +E V+A GFPQ+FVGV+IA L Sbjct 208 EDESHADPPSTREALVSLVLLLCALVAVVGLAEEESPAVERAVTAVGFPQTFVGVIIAAL 267 Query 260 VLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQL 319 VLLPETLAA RAARQGR+Q SLNLAYGSAMASIGLTIP IALAS+WL GPL LGLGAIQL Sbjct 268 VLLPETLAAVRAARQGRIQISLNLAYGSAMASIGLTIPAIALASIWLKGPLVLGLGAIQL 327 Query 320 VLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 VLL LTVV+SVLTVVPGRATRLQGEVHLVLLAAY+FLAV P Sbjct 328 VLLALTVVISVLTVVPGRATRLQGEVHLVLLAAYVFLAVSP 368 >gi|296164474|ref|ZP_06847046.1| calcium/proton antiporter membrane protein ChaA [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900172|gb|EFG79606.1| calcium/proton antiporter membrane protein ChaA [Mycobacterium parascrofulaceum ATCC BAA-614] Length=359 Score = 461 bits (1187), Expect = 6e-128, Method: Compositional matrix adjust. Identities = 281/357 (79%), Positives = 308/357 (87%), Gaps = 3/357 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT +P LA L WG+++GP + LAA L GAVLAAV+HAEVVAARVGEPFGSLVL Sbjct 3 WTAAVPLLAVGMLAAVWGEKLGPALVALAAAFLIGAVLAAVHHAEVVAARVGEPFGSLVL 62 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 A AVT IEVALIV LM SGG++AATLARDTVFAAVMITTNGIAGLSLLLGS RYGVTLFN Sbjct 63 AAAVTVIEVALIVELMASGGNEAATLARDTVFAAVMITTNGIAGLSLLLGSRRYGVTLFN 122 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 GSGAALAT+TTL TLSLVLP FTTS SG E SPGQL FA ASL LY++F+FTQTVRH Sbjct 123 AEGSGAALATLTTLGTLSLVLPAFTTSGSGKEFSPGQLTFAAVASLLLYLVFVFTQTVRH 182 Query 187 RDFFLPVAQKGA---VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 RDFFLPVAQKG ED+SHA+PPS AAL SLGLLLVALVAVVGLA+ ESP +E V+ Sbjct 183 RDFFLPVAQKGQKRLFEDESHAEPPSRSAALGSLGLLLVALVAVVGLAEEESPALESAVT 242 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 A GFPQSFVGVVIA+LVLLPETL+A RAARQGR+QTSLNLAYGSAMASIGLTIPTIALAS Sbjct 243 AVGFPQSFVGVVIASLVLLPETLSAVRAARQGRIQTSLNLAYGSAMASIGLTIPTIALAS 302 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +WL GPL LGLGAIQLVLL LTVV+S+LTV+PGRATRLQGEVHLVLLAAY+FL++ P Sbjct 303 IWLKGPLVLGLGAIQLVLLALTVVISMLTVIPGRATRLQGEVHLVLLAAYVFLSISP 359 >gi|84497995|ref|ZP_00996792.1| Probable ionic transporter integral membrane protein chaA [Janibacter sp. HTCC2649] gi|84381495|gb|EAP97378.1| Probable ionic transporter integral membrane protein chaA [Janibacter sp. HTCC2649] Length=375 Score = 445 bits (1144), Expect = 6e-123, Method: Compositional matrix adjust. Identities = 241/355 (68%), Positives = 275/355 (78%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT + P LA +AL LTWG+ I +V + A+LL GAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 21 WTTISPVLALIALALTWGRDINGIVVGVIALLLGGAVLAAVHHAEVVAHRVGEPFGSLVL 80 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEV+LIV LM+SGG +TLARDTVFAAVMIT NGI GLSLL+GS R+G+ FN Sbjct 81 AVAVTVIEVSLIVTLMLSGGAGTSTLARDTVFAAVMITVNGILGLSLLVGSRRFGMIRFN 140 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+G ALATV TLAT+ LVLPT TT + GP + QL+FA ASL LY F+ TQTVRH Sbjct 141 AEGTGGALATVATLATVCLVLPTVTTGEVGPVFTSSQLVFAAVASLSLYAAFVLTQTVRH 200 Query 187 RDFFLPVAQKGA-VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RDFFLPV KG + +D HA PPS A SLG L ++LVAVVGLAKVES IEE VSAA Sbjct 201 RDFFLPVGSKGKPLPEDEHATPPSNNQAWSSLGFLFLSLVAVVGLAKVESKSIEEAVSAA 260 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G P SFVGVVIA LVLLPETLAA AAR+ R+QTS+NLA GSAMASIGLTIP +A+A++W Sbjct 261 GLPHSFVGVVIALLVLLPETLAAVNAARRERIQTSINLALGSAMASIGLTIPVLAIATIW 320 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 + PL LGL A Q+ LL +T+V VLTVVPGRATRLQ VHL L AAYLFLA VP Sbjct 321 IDTPLHLGLDATQITLLAITIVTGVLTVVPGRATRLQASVHLTLCAAYLFLAAVP 375 >gi|256377804|ref|YP_003101464.1| sodium/calcium exchanger membrane protein [Actinosynnema mirum DSM 43827] gi|255922107|gb|ACU37618.1| sodium/calcium exchanger membrane region [Actinosynnema mirum DSM 43827] Length=371 Score = 426 bits (1096), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 246/351 (71%), Positives = 284/351 (81%), Gaps = 7/351 (1%) Query 3 KRVP----WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVG 58 R+P WT V+P L+ +AL+ TWG++ GP++ + A++LAG+VLAAV+HAEVVA RVG Sbjct 7 SRIPPMLSWTNVVPVLSLLALLFTWGRETGPILVTVVALMLAGSVLAAVHHAEVVAHRVG 66 Query 59 EPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSL 118 EPFGSLVLAVAVT IEVALIV LM+SGG +AATLARDTVFAAVMITTNGI GLSLL G+L Sbjct 67 EPFGSLVLAVAVTIIEVALIVTLMISGGPEAATLARDTVFAAVMITTNGIIGLSLLRGAL 126 Query 119 RYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLF 178 +Y V FN GSGAALATVTTLA LS+V+PTFTT +GPE + QL+FA ASL LY +F Sbjct 127 KYQVVPFNAEGSGAALATVTTLAVLSMVVPTFTTGAAGPEFTTPQLVFAALASLALYGMF 186 Query 179 LFTQTVRHRDFFLPVAQKGAV---EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVES 235 +F QTV+HRDFFLPV + +D HA PPS R A SLGLLLVALVAVVGLAKVES Sbjct 187 VFAQTVKHRDFFLPVDMEDEAPVDSNDEHAPPPSNREAWTSLGLLLVALVAVVGLAKVES 246 Query 236 PVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLT 295 P IE V++ G PQSFVGVVIA LVLLPETLAA RAA +GR+Q SLNL YGSAMASIGLT Sbjct 247 PAIEAGVASLGLPQSFVGVVIALLVLLPETLAAVRAAGRGRVQISLNLGYGSAMASIGLT 306 Query 296 IPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVH 346 +P IALA++WL GPL LGL A Q+VLL +TVVVS+LTVVPGRATRLQG VH Sbjct 307 VPVIALATIWLDGPLMLGLEATQMVLLAMTVVVSMLTVVPGRATRLQGGVH 357 >gi|21220447|ref|NP_626226.1| ionic transporter [Streptomyces coelicolor A3(2)] gi|289772317|ref|ZP_06531695.1| ionic transporter [Streptomyces lividans TK24] gi|4468698|emb|CAB38152.1| ionic transporter [Streptomyces coelicolor A3(2)] gi|289702516|gb|EFD69945.1| ionic transporter [Streptomyces lividans TK24] Length=366 Score = 417 bits (1071), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 247/356 (70%), Positives = 285/356 (81%), Gaps = 3/356 (0%) Query 7 WTVVLPSLAFVALVLTWGKQI-GPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WT V P +A V L LTWG+ + G VV LL ++LA +VLAAV+HAEVVA RVGEPFGSLV Sbjct 12 WTTVTPVIAVVLLALTWGRSLPGAVVALLT-IVLAASVLAAVHHAEVVAHRVGEPFGSLV 70 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LA+AVT IEVALIV LMV GGD +ATLARDTVFAAVMIT NG+ GLSLL+ SLR+G +F Sbjct 71 LAIAVTVIEVALIVTLMVDGGDKSATLARDTVFAAVMITCNGVVGLSLLVASLRHGTAVF 130 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 NP G+GAALATV TLATLSLVLPTFTTS GPE S QL FA +SL LY LF+ T TVR Sbjct 131 NPEGTGAALATVATLATLSLVLPTFTTSAPGPEFSTVQLTFAALSSLVLYGLFIATLTVR 190 Query 186 HRDFFLPVAQKGAV-EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSA 244 HRD+FLP+ ++G V + HA PS+R AL SLG+L +ALV VVGLAK SP IE+ V+A Sbjct 191 HRDYFLPITRQGEVITFEEHAHAPSSRTALTSLGMLGLALVGVVGLAKGVSPTIEDGVAA 250 Query 245 AGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASL 304 AG + VGV+IA LVLLPET+AA R+AR+ R+QTSLNLA GSAMASIGLTIP +ALAS+ Sbjct 251 AGLHHAVVGVIIALLVLLPETIAAVRSARRDRVQTSLNLALGSAMASIGLTIPAVALASV 310 Query 305 WLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 WL+GPL LGLG+I +VLL LTVVV+ LTVVPGRAT LQG VHLVL AAYL LAV P Sbjct 311 WLTGPLVLGLGSIHMVLLALTVVVASLTVVPGRATPLQGGVHLVLFAAYLELAVNP 366 >gi|300786409|ref|YP_003766700.1| Ca2+/H+ antiporter [Amycolatopsis mediterranei U32] gi|299795923|gb|ADJ46298.1| Ca2+/H+ antiporter [Amycolatopsis mediterranei U32] gi|340527886|gb|AEK43091.1| Ca2+/H+ antiporter [Amycolatopsis mediterranei S699] Length=365 Score = 412 bits (1058), Expect = 6e-113, Method: Compositional matrix adjust. Identities = 267/354 (76%), Positives = 290/354 (82%), Gaps = 0/354 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT V P L + L L WG+ +GPV + AV L VLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTSVTPVLGVLVLALAWGRDLGPVFVAVVAVALGATVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV +MVSGG +A +LARDTVFAAVMITTNGI G+SLL+G+ RYG TLFN Sbjct 72 AVAVTVIEVALIVTMMVSGGPEAGSLARDTVFAAVMITTNGIVGISLLVGARRYGSTLFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 GSGAALATVTTLATLSLVLP FTTS GP SP QL FA ASL LY F+ TQTVRH Sbjct 132 SEGSGAALATVTTLATLSLVLPAFTTSTPGPAFSPTQLTFAALASLVLYGTFVLTQTVRH 191 Query 187 RDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAG 246 RDFFLPVA GAV++D HADPPS RAAL SL LLLVALVAVVGLAKVESP IE V AAG Sbjct 192 RDFFLPVAADGAVKEDDHADPPSNRAALGSLALLLVALVAVVGLAKVESPAIEAGVRAAG 251 Query 247 FPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWL 306 FPQSFVGVVIA LVLLPETLAA RAA++ R+Q SLNLAYGSA+ASIGLTIP IALAS+WL Sbjct 252 FPQSFVGVVIALLVLLPETLAATRAAQRDRMQISLNLAYGSAIASIGLTIPAIALASVWL 311 Query 307 SGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 G L LGLG+ Q+VLL LTVVVSVLTVVPGRATRLQG VHLVLLA +L LA+ P Sbjct 312 PGRLLLGLGSTQIVLLALTVVVSVLTVVPGRATRLQGGVHLVLLAGFLVLAINP 365 >gi|294628744|ref|ZP_06707304.1| cation/proton antiporter [Streptomyces sp. e14] gi|292832077|gb|EFF90426.1| cation/proton antiporter [Streptomyces sp. e14] Length=366 Score = 409 bits (1052), Expect = 3e-112, Method: Compositional matrix adjust. Identities = 237/355 (67%), Positives = 274/355 (78%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT +P LA V L LTWG+ + V +L +LAG+VLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTTAVPVLAVVLLALTWGRSLPVAVVVLVTAVLAGSVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM GGD +ATLARDTVFAAVMIT NG+ GL LL+ S+R+G +FN Sbjct 72 AVAVTVIEVALIVTLMADGGDKSATLARDTVFAAVMITCNGVIGLCLLVASMRHGTAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+ AAL TV TLATLSLVLPTFTTS+ GPE S QL FA +SL LY LF+ T TVRH Sbjct 132 AEGTIAALGTVATLATLSLVLPTFTTSKPGPEFSGVQLTFAALSSLILYGLFVATLTVRH 191 Query 187 RDFFLPVAQKGAV-EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RD+FLP+ ++G V D HA PS R A SLGLL +ALV VVGLAK SP IE V+AA Sbjct 192 RDYFLPITRQGDVITSDHHAASPSARTAWTSLGLLGIALVGVVGLAKSVSPTIESGVAAA 251 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G + VGV+IA LVLLPET+AA R+AR+ R+QTSLNLA GSAMASIGLTIP +ALAS+W Sbjct 252 GLHHAVVGVIIALLVLLPETIAALRSARRDRMQTSLNLALGSAMASIGLTIPAVALASVW 311 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 L GPL LGLG+ ++LL+LTVVV LTVVPGRAT LQG VHLV+ AAYL LA+ P Sbjct 312 LPGPLVLGLGSTHMLLLLLTVVVGSLTVVPGRATPLQGGVHLVIFAAYLELAINP 366 >gi|226359807|ref|YP_002777585.1| Ca(2+)/H(+) antiporter [Rhodococcus opacus B4] gi|226238292|dbj|BAH48640.1| putative Ca(2+)/H(+) antiporter [Rhodococcus opacus B4] Length=365 Score = 407 bits (1045), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 248/354 (71%), Positives = 281/354 (80%), Gaps = 0/354 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 W +V+P +A L +TWG+ IG VV L AV+L GAVLAAV+HAEVVA +VGEPFGSL+L Sbjct 12 WPLVIPPVAVAVLGVTWGRHIGTVVVLAVAVVLVGAVLAAVHHAEVVAHKVGEPFGSLIL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEV LIV LM+SGG A+LARDTVFAAVMIT NGIAGLSL +GS RYGV LFN Sbjct 72 AVAVTVIEVGLIVTLMISGGPATASLARDTVFAAVMITVNGIAGLSLFVGSRRYGVALFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+GAALATV +LATLSLVLPTFTTS+ GPE S QLIFA ASL LY +F+ TQT H Sbjct 132 AEGTGAALATVASLATLSLVLPTFTTSRPGPEFSSAQLIFAAVASLVLYGMFVLTQTGPH 191 Query 187 RDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAG 246 R FFLPV D + PP+ R A +SL LL+VAL AVVGLAKVESP IE+ V AG Sbjct 192 RHFFLPVIADEPETGDRSSAPPTGRMAGVSLALLVVALCAVVGLAKVESPAIEDAVEDAG 251 Query 247 FPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWL 306 PQS VGVVIA LVLLPETLAA RAA++ R+Q SLNLA+GSAMASIGLTIP IA+AS+WL Sbjct 252 LPQSIVGVVIALLVLLPETLAAVRAAQRNRIQISLNLAFGSAMASIGLTIPAIAVASIWL 311 Query 307 SGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 GPL LGLG Q+VLL +TVVV +LTVVPGRATRLQG VHLVLLAAY+FL+V P Sbjct 312 DGPLLLGLGPTQVVLLAITVVVGMLTVVPGRATRLQGGVHLVLLAAYVFLSVNP 365 >gi|297196373|ref|ZP_06913771.1| ionic transporter integral membrane protein [Streptomyces pristinaespiralis ATCC 25486] gi|197720848|gb|EDY64756.1| ionic transporter integral membrane protein [Streptomyces pristinaespiralis ATCC 25486] Length=374 Score = 405 bits (1042), Expect = 4e-111, Method: Compositional matrix adjust. Identities = 252/366 (69%), Positives = 287/366 (79%), Gaps = 13/366 (3%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLA-AVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WTV +P +A VALVL+WG+ + P++ ++A A+ LAGAVLAAV+HAEVVA RVGEPFGSLV Sbjct 10 WTVWVPLVALVALVLSWGRDL-PLLAVVAVALCLAGAVLAAVHHAEVVAHRVGEPFGSLV 68 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LAVAVT IEVALIV LMV GGD +A+LARDTVFAAVMIT NGI GLSLL+G+LR + +F Sbjct 69 LAVAVTVIEVALIVTLMVDGGDKSASLARDTVFAAVMITCNGIVGLSLLVGALRRRIAVF 128 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 N GSGAALATV TLATLSLVLPTFTTS+ GPE S QL FA ASLGLY LF+ QTVR Sbjct 129 NAEGSGAALATVATLATLSLVLPTFTTSKPGPEFSAAQLTFAAVASLGLYGLFVAMQTVR 188 Query 186 HRDFFLPVAQKGAV-----------EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVE 234 HRD FL VA++GAV +DD H+ PS AL SL +LL+AL+AVVG AK Sbjct 189 HRDHFLSVAREGAVKDGALSDDVGFDDDEHSGVPSRSIALFSLVMLLIALIAVVGDAKAV 248 Query 235 SPVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGL 294 SP IE V +AG P S VGVVIA LVL+PETLAA RAAR+ ++Q SLNLA GSAMASIGL Sbjct 249 SPTIESGVDSAGLPHSVVGVVIALLVLMPETLAAVRAARRDQVQRSLNLALGSAMASIGL 308 Query 295 TIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYL 354 TIP IALAS+WL GPL LGLGA +VLL LTVVV LTVVPGRAT LQG VHL +LAAY+ Sbjct 309 TIPVIALASIWLEGPLLLGLGATHMVLLALTVVVGALTVVPGRATLLQGGVHLAILAAYV 368 Query 355 FLAVVP 360 FLAV P Sbjct 369 FLAVSP 374 >gi|311894269|dbj|BAJ26677.1| putative calcium/proton antiporter [Kitasatospora setae KM-6054] Length=367 Score = 404 bits (1039), Expect = 9e-111, Method: Compositional matrix adjust. Identities = 226/357 (64%), Positives = 272/357 (77%), Gaps = 4/357 (1%) Query 7 WTVVLPSLAFVALVLTWGKQI-GPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WT V P LAF+ L+ TW + + PVV L+A LA +V+AAV+HAE++A RVGEP+GSLV Sbjct 12 WTTVAPVLAFLLLLATWHRDLPWPVVALVAC-FLAVSVVAAVHHAELIAHRVGEPYGSLV 70 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LAVAVT IEVALIV LM GGD +A LARDTVFAAVMIT NGI GLS+L+G+L+Y V +F Sbjct 71 LAVAVTIIEVALIVTLMADGGDKSAGLARDTVFAAVMITCNGILGLSILVGALKYRVAVF 130 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 N G+GAA + TLATLSLVLPTFTTSQ GP+ S QL+FA AS+ +Y LF+ T TVR Sbjct 131 NAEGTGAAFGAIATLATLSLVLPTFTTSQPGPQFSTTQLVFAATASIVIYGLFVSTLTVR 190 Query 186 HRDFFLPVAQKGAVED--DSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 HRD+FLPV G + D D H++PP+ R + S+ LL VALV+VVGLAK SP IE V+ Sbjct 191 HRDYFLPVTPAGEIVDPMDDHSEPPTLRQTMTSVALLSVALVSVVGLAKGVSPTIERGVA 250 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 AA P + VGVVIA LVLLPE++AA RAA + R+Q SLNLA GSA+ASIGLTIP +A+AS Sbjct 251 AADLPNAVVGVVIALLVLLPESIAAVRAAVRNRVQISLNLALGSALASIGLTIPAVAVAS 310 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 WLSGPL+LGLGA ++LL LTV V LTV+P RAT LQG VHL +L AYL LAV P Sbjct 311 TWLSGPLELGLGANHMILLALTVAVGTLTVIPKRATPLQGGVHLAILGAYLVLAVSP 367 >gi|297198913|ref|ZP_06916310.1| ionic transporter integral membrane protein [Streptomyces sviceus ATCC 29083] gi|197711166|gb|EDY55200.1| ionic transporter integral membrane protein [Streptomyces sviceus ATCC 29083] Length=366 Score = 403 bits (1035), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 244/355 (69%), Positives = 282/355 (80%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT +P LA V LV TWG+ + V L ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTSFVPVLAAVLLVFTWGRDLPAAVVALVTLVLAGAVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM GGD ++TLARDTVFAAVMIT NGI G+SLL+ SLR+G +FN Sbjct 72 AVAVTIIEVALIVTLMADGGDKSSTLARDTVFAAVMITCNGIVGISLLVASLRHGTAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P G+GAALATV TLATLSLVLPTFTTS+ GPE S QL FA +SL LY LF+ TQTVRH Sbjct 132 PEGTGAALATVATLATLSLVLPTFTTSKPGPEFSTTQLTFAALSSLILYGLFVATQTVRH 191 Query 187 RDFFLPVAQKGAVED-DSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RD+FLP+ ++G V D HA P+ RAAL+SLGLL +AL+ VVGLAK SP IE V+ A Sbjct 192 RDYFLPITRQGEVITVDDHAHAPTARAALISLGLLGLALIGVVGLAKGVSPTIESGVARA 251 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G P + VGV+IA LVLLPET+AA R+AR+ R+QTSLNLA GSAMASIGLTIP +ALA++W Sbjct 252 GLPHAVVGVIIALLVLLPETIAALRSARRDRVQTSLNLALGSAMASIGLTIPAVALATVW 311 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LSGPL LGLG+ +VLL LTV VS LTVVPGRAT LQG VHLV+ AAYL LA+ P Sbjct 312 LSGPLVLGLGSTHMVLLALTVAVSSLTVVPGRATPLQGGVHLVVFAAYLELAINP 366 >gi|290961298|ref|YP_003492480.1| ion exchange transporter [Streptomyces scabiei 87.22] gi|260650824|emb|CBG73941.1| putative ion exchange transporter [Streptomyces scabiei 87.22] Length=366 Score = 401 bits (1031), Expect = 8e-110, Method: Compositional matrix adjust. Identities = 249/355 (71%), Positives = 283/355 (80%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT V+P A V L LTWG+ + P L ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTDVVPVAAVVLLALTWGRDLPPGAVALVTLVLAGAVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+ GGD +ATLARDTVFAAVMIT NGI G+ LL+ SLR+G+ +FN Sbjct 72 AVAVTIIEVALIVTLMIDGGDKSATLARDTVFAAVMITCNGIVGICLLVASLRHGLAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P G+GAALATV TLATLSLVLPTFTTS+ GPE S QL FA +SL LY LF+ TQTVRH Sbjct 132 PEGTGAALATVATLATLSLVLPTFTTSKPGPEFSTAQLTFAALSSLALYGLFVATQTVRH 191 Query 187 RDFFLPVAQKGAV-EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RD+FLP+ + G V +D HA+ PS R A +SLG+L +ALV VVGLAK SP IE V AA Sbjct 192 RDYFLPITRMGEVIAEDDHAEAPSARTAKISLGMLGLALVGVVGLAKGVSPTIESGVDAA 251 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G P + VGVVIA LVLLPET+AA RAAR+ R+QTSLNLA GSAMASIGLTIP +ALAS+W Sbjct 252 GMPHAVVGVVIALLVLLPETIAALRAARRDRVQTSLNLALGSAMASIGLTIPAVALASVW 311 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LSGPL LGLG+ +VLL LTVVV+ LTVVPGRAT LQG VHLVL AAYL LAV P Sbjct 312 LSGPLVLGLGSTHMVLLALTVVVASLTVVPGRATPLQGGVHLVLFAAYLELAVNP 366 >gi|294811001|ref|ZP_06769644.1| ionic transporter [Streptomyces clavuligerus ATCC 27064] gi|326439657|ref|ZP_08214391.1| ionic transporter [Streptomyces clavuligerus ATCC 27064] gi|294323600|gb|EFG05243.1| ionic transporter [Streptomyces clavuligerus ATCC 27064] Length=371 Score = 400 bits (1027), Expect = 3e-109, Method: Compositional matrix adjust. Identities = 235/356 (67%), Positives = 270/356 (76%), Gaps = 2/356 (0%) Query 7 WTVV-LPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WT +P +A VAL L WG+++ L + L GAVLAAV+HAEV+A RVGEPFGSLV Sbjct 16 WTTSWVPLVAIVALALGWGRELPGFALALIGLCLIGAVLAAVHHAEVIAHRVGEPFGSLV 75 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LAVAVT IEV LIV LM GGD A+T ARDTVFAAVMIT NGI G+SLL+G+LR V +F Sbjct 76 LAVAVTVIEVGLIVTLMAEGGDKASTYARDTVFAAVMITCNGIVGISLLVGTLRNRVAVF 135 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 N GSG ALATV TLAT++LVLPTFTTS G E + GQL FA +SL LY LF+ QTVR Sbjct 136 NAEGSGGALATVCTLATMTLVLPTFTTSHPGLEFTGGQLAFAAVSSLCLYALFVGVQTVR 195 Query 186 HRDFFLPVAQ-KGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSA 244 HRD+FLPV G D HA PP R L S+ LL+VAL+AVVG AK+ SP IE V + Sbjct 196 HRDYFLPVRTGAGECGPDDHAPPPGGRETLSSVVLLVVALIAVVGNAKLVSPAIEGAVDS 255 Query 245 AGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASL 304 AG P++ VGV IA LVLLPETLAAARAAR+ RLQTSLNLAYGSA+ASIGLTIP+IALAS+ Sbjct 256 AGLPKAVVGVAIALLVLLPETLAAARAARRNRLQTSLNLAYGSAIASIGLTIPSIALASI 315 Query 305 WLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 WLSGPL LG A+ +VLL LT VVS LTVVPGRAT LQG VHL L AA++FL+ P Sbjct 316 WLSGPLVLGEDAVHMVLLALTAVVSALTVVPGRATLLQGGVHLALFAAFVFLSFSP 371 >gi|302526422|ref|ZP_07278764.1| ionic transporter integral membrane protein ChaA [Streptomyces sp. AA4] gi|302435317|gb|EFL07133.1| ionic transporter integral membrane protein ChaA [Streptomyces sp. AA4] Length=357 Score = 399 bits (1024), Expect = 4e-109, Method: Compositional matrix adjust. Identities = 256/354 (73%), Positives = 283/354 (80%), Gaps = 0/354 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT +LP +A V L LTWG+ +GPV L A+ LAG VLAAV+HAEVVA RVGEP+GSLVL Sbjct 4 WTTLLPLVALVLLALTWGRTLGPVPVALVAIALAGTVLAAVHHAEVVAHRVGEPYGSLVL 63 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV +M SGG+ A TLARDTVFAAVMITTNGI GLSLL+G+ RYG T F+ Sbjct 64 AVAVTVIEVALIVTMMASGGEKADTLARDTVFAAVMITTNGIVGLSLLVGARRYGETRFH 123 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P GSGAALATV TLATLSLVLPTFT S GP S QL FA ASL LY F+ TQTVRH Sbjct 124 PEGSGAALATVGTLATLSLVLPTFTASTPGPAFSAPQLAFAAGASLILYATFVMTQTVRH 183 Query 187 RDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAG 246 RDFFLPV G ++ HA+PPS + L+SL LLL+ALV VVGLAKVESP IE V AAG Sbjct 184 RDFFLPVGADGETREEEHAEPPSAQKTLVSLVLLLIALVTVVGLAKVESPAIEAGVRAAG 243 Query 247 FPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWL 306 PQSFVGVVIA L+L PETLAA RAAR+ R+Q SLNLAYGSA+ASIGLTIP IALAS+WL Sbjct 244 LPQSFVGVVIALLILAPETLAAVRAARRDRMQISLNLAYGSAIASIGLTIPVIALASVWL 303 Query 307 SGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 GPL LGLG +VLL LTVVVSVLTVVPGRATRLQG VHLVLLA +L LA+ P Sbjct 304 KGPLLLGLGPTHIVLLALTVVVSVLTVVPGRATRLQGGVHLVLLAGFLVLAMNP 357 >gi|50955406|ref|YP_062694.1| calcium/proton antiporter [Leifsonia xyli subsp. xyli str. CTCB07] gi|50951888|gb|AAT89589.1| calcium/proton antiporter [Leifsonia xyli subsp. xyli str. CTCB07] Length=376 Score = 395 bits (1016), Expect = 5e-108, Method: Compositional matrix adjust. Identities = 228/355 (65%), Positives = 274/355 (78%), Gaps = 3/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 W + +P + + LV W +G L V LAG VLAAV HA+VVA RVGEPFGSLVL Sbjct 24 WAICVPVIGVILLVGFWTVPLGAFSITLIGVFLAGTVLAAVQHADVVAHRVGEPFGSLVL 83 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM +G D+ TLARDTVF+AVMIT NGI GLSLLL + R T FN Sbjct 84 AVAVTVIEVALIVTLMTTG-KDSETLARDTVFSAVMITMNGIVGLSLLLAASRRETTSFN 142 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 GSG+AL TVT LA L++V+P FT + GP+ SP QL FA AS+ LY +F+FTQTV H Sbjct 143 AQGSGSALGTVTALAALTMVVPAFTET-PGPQFSPSQLWFAAIASVLLYAMFVFTQTVAH 201 Query 187 RDFFLPVAQKGA-VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RDFFLPV+ K + +DSHAD S R AL+SLG+LL+ALVAVVGLAK+ES IE V+AA Sbjct 202 RDFFLPVSTKERPIAEDSHADATSNRTALISLGMLLIALVAVVGLAKLESTPIERAVTAA 261 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G PQSFVGVVIA LVLLPE +AAA+AAR+ R+QTSLNLA GSA+ASIGLTIP+IA+AS+W Sbjct 262 GLPQSFVGVVIALLVLLPEGIAAAKAARRNRMQTSLNLALGSAIASIGLTIPSIAIASIW 321 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 L G L LGLGA Q+VLL LTV VS+LT+V GRA R+QG +HL++ AA++FL++VP Sbjct 322 LPGALHLGLGASQIVLLALTVAVSILTIVQGRAARMQGTIHLIIFAAFIFLSIVP 376 >gi|302550662|ref|ZP_07303004.1| ionic transporter integral membrane protein [Streptomyces viridochromogenes DSM 40736] gi|302468280|gb|EFL31373.1| ionic transporter integral membrane protein [Streptomyces viridochromogenes DSM 40736] Length=366 Score = 395 bits (1014), Expect = 7e-108, Method: Compositional matrix adjust. Identities = 250/363 (69%), Positives = 287/363 (80%), Gaps = 5/363 (1%) Query 3 KRVP----WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVG 58 +R P WT ++P LA V LVLTWG+ + V+ L ++LAGAVLAAV+HAEVVA RVG Sbjct 4 RRRPLTAQWTTLVPLLAAVLLVLTWGRDLPGVIVALMTLVLAGAVLAAVHHAEVVAHRVG 63 Query 59 EPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSL 118 EPFGSLVLA+AVT IEVALIV LMV GGD +TLARDTVFAAVMIT NGI GL LL+ SL Sbjct 64 EPFGSLVLAIAVTIIEVALIVTLMVDGGDKTSTLARDTVFAAVMITCNGIVGLCLLVASL 123 Query 119 RYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLF 178 R+G +FNP G+GAALATV TLATLSLVLPTFTTS+ GPE S QL FA +SL LY LF Sbjct 124 RHGTAVFNPEGTGAALATVATLATLSLVLPTFTTSKPGPEFSTVQLTFAALSSLVLYGLF 183 Query 179 LFTQTVRHRDFFLPVAQKGAV-EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPV 237 + TQTVRHRD+FLP+ + G V + HA+ P+ R AL+SLGLL +AL+ VVGLAK SP Sbjct 184 VATQTVRHRDYFLPITRHGEVITSEEHAEAPTARTALISLGLLGLALIGVVGLAKGVSPT 243 Query 238 IEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIP 297 IE V AAG Q+ VGV+IA LVLLPET+AA R+AR+ R+QTSLNLA GSAMASIGLTIP Sbjct 244 IESGVEAAGLHQAVVGVIIALLVLLPETIAALRSARRDRVQTSLNLALGSAMASIGLTIP 303 Query 298 TIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLA 357 +ALAS+WLSGPL LGLGA +VLL LTVVV+ LTVVPGRAT LQG VHLVL AAYL LA Sbjct 304 AVALASVWLSGPLVLGLGATHMVLLALTVVVASLTVVPGRATPLQGGVHLVLFAAYLELA 363 Query 358 VVP 360 V P Sbjct 364 VNP 366 >gi|302532824|ref|ZP_07285166.1| ionic transporter integral membrane protein [Streptomyces sp. C] gi|302441719|gb|EFL13535.1| ionic transporter integral membrane protein [Streptomyces sp. C] Length=373 Score = 394 bits (1013), Expect = 8e-108, Method: Compositional matrix adjust. Identities = 252/368 (69%), Positives = 283/368 (77%), Gaps = 10/368 (2%) Query 3 KRVP---WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGE 59 +R P WT+++P +A VALV +WG+ + L A+ LAGAVLAAV+HAEVVA RVGE Sbjct 6 RRSPLTDWTLLVPVVALVALVFSWGRDLPGFAVALVALCLAGAVLAAVHHAEVVAHRVGE 65 Query 60 PFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLR 119 PFGSLVLAVAVT IEVALIV LM GGD A+LARDTVFAAVMIT NGI GLSLL+G+LR Sbjct 66 PFGSLVLAVAVTVIEVALIVTLMADGGDKTASLARDTVFAAVMITCNGIVGLSLLVGALR 125 Query 120 YGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFL 179 V +FN GSGAALATV TLA LSLVLPTFTTS+ GPE S QL FA ASL LY LF+ Sbjct 126 NRVAVFNAEGSGAALATVATLAVLSLVLPTFTTSKPGPEFSSAQLTFAAVASLALYGLFI 185 Query 180 FTQTVRHRDFFLPVAQKG-------AVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAK 232 QTVRHRD+FLPV D HA+PP+ RAAL+SLGLL VALVAVVG AK Sbjct 186 AVQTVRHRDYFLPVDTGNTGQGPGSGDGDGDHAEPPTARAALISLGLLFVALVAVVGNAK 245 Query 233 VESPVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASI 292 SP IE+ VS AG P + VGV+IA LVL PETLAA RAAR+ R+QTSLNLAYGSA+ASI Sbjct 246 AVSPTIEKGVSDAGLPHAVVGVIIALLVLAPETLAAVRAARRDRVQTSLNLAYGSAIASI 305 Query 293 GLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAA 352 GLTIP IALAS+WL+GPL LGL + +VLL LTVVV LT+VPGRAT LQG VHLVLLAA Sbjct 306 GLTIPAIALASVWLTGPLVLGLAPLHMVLLALTVVVGALTIVPGRATLLQGGVHLVLLAA 365 Query 353 YLFLAVVP 360 YLFLAV P Sbjct 366 YLFLAVSP 373 >gi|291440306|ref|ZP_06579696.1| ionic transporter [Streptomyces ghanaensis ATCC 14672] gi|291343201|gb|EFE70157.1| ionic transporter [Streptomyces ghanaensis ATCC 14672] Length=366 Score = 389 bits (1000), Expect = 3e-106, Method: Compositional matrix adjust. Identities = 245/361 (68%), Positives = 286/361 (80%), Gaps = 9/361 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT ++P LA + LV TWG+++ + +A ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 8 WTTLVPPLAVILLVFTWGRELPGGIVAVATLVLAGAVLAAVHHAEVVAHRVGEPFGSLVL 67 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+ GGD +ATLARDTVFAAVMIT NGI GLSLL+GSLR+G +FN Sbjct 68 AVAVTVIEVALIVTLMMDGGDKSATLARDTVFAAVMITCNGILGLSLLVGSLRHGTAVFN 127 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 GSG+ALATV TLATLSLVLPTFTTS+ GPE S QL FA SL LY LF+ TQTVRH Sbjct 128 SEGSGSALATVATLATLSLVLPTFTTSKPGPEFSSVQLTFAAVISLVLYGLFVATQTVRH 187 Query 187 RDFFLPVAQK-------GAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIE 239 RD+FLPV ++ G VE+ HA+ PS R AL+SLGLL +AL+ VVGLAK SP IE Sbjct 188 RDYFLPVPRQEKGDTSAGPVEE--HAEAPSARTALISLGLLGLALIGVVGLAKGVSPAIE 245 Query 240 EVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTI 299 V AG P + VGV+IA LVLLPET+AA RAAR+ ++Q S+NLA GSAMASIGLTIP + Sbjct 246 SAVDTAGLPHAIVGVIIALLVLLPETIAAVRAARRDQVQISMNLALGSAMASIGLTIPAV 305 Query 300 ALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVV 359 ALASLWL+GPL LGL + +VLL+LTV+VS LTVVPGRAT LQG VHLVLLAAYL LA+ Sbjct 306 ALASLWLTGPLILGLSSTHMVLLLLTVLVSALTVVPGRATPLQGGVHLVLLAAYLELAIN 365 Query 360 P 360 P Sbjct 366 P 366 >gi|326331324|ref|ZP_08197616.1| cation/proton antiporter [Nocardioidaceae bacterium Broad-1] gi|325950957|gb|EGD43005.1| cation/proton antiporter [Nocardioidaceae bacterium Broad-1] Length=360 Score = 385 bits (990), Expect = 5e-105, Method: Compositional matrix adjust. Identities = 229/360 (64%), Positives = 273/360 (76%), Gaps = 8/360 (2%) Query 9 VVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAV 68 +V+P LA V LVL W + + + A +L GAVL+AV+HAEVVA +VGEPFGSL+LA+ Sbjct 1 MVVPILALVVLVLAWLRHDHWTILAVVAAVLIGAVLSAVHHAEVVAHKVGEPFGSLILAI 60 Query 69 AVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPH 128 AVT IEV LIV LM SGGD+ +T ARDTVFAAVMIT NGI GLSL++G+L++G+ FN Sbjct 61 AVTVIEVGLIVMLMTSGGDNTSTYARDTVFAAVMITLNGIVGLSLMVGALKHGLVSFNAA 120 Query 129 GSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRD 188 G+G+A+ATV LA L+LVLP FTTS GP+ SP QL FA ASL LYV FLFTQTVRHRD Sbjct 121 GTGSAVATVIALAGLTLVLPRFTTSAQGPQYSPSQLAFAAIASLALYVAFLFTQTVRHRD 180 Query 189 FFLPVAQKGA--------VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 FFLPV +++DSHADPPS A LSL LLLV+LV+VVGLAKV SP IE Sbjct 181 FFLPVTSDEHGRMTGIVDLDEDSHADPPSAGEAGLSLALLLVSLVSVVGLAKVLSPTIES 240 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 V GFP + VGVVIA LVL PE++AA R A + R+QTSLNLAYGSAMASIGLTIPTIA Sbjct 241 TVKNLGFPYAVVGVVIALLVLAPESIAAVRNASRDRVQTSLNLAYGSAMASIGLTIPTIA 300 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +A +WLSGPL LGL Q+VLLV+TV V+ LTVV GR LQG VHLVL+A++LFL++ P Sbjct 301 VAMIWLSGPLVLGLEPTQIVLLVITVFVTGLTVVQGRVYALQGFVHLVLMASFLFLSIQP 360 >gi|297626041|ref|YP_003687804.1| ionic transporter integral membrane protein [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] gi|296921806|emb|CBL56366.1| ionic transporter integral membrane protein [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] Length=366 Score = 384 bits (985), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 219/362 (61%), Positives = 268/362 (75%), Gaps = 7/362 (1%) Query 3 KRVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVL---LAGAVLAAVNHAEVVAARVGE 59 K + WT VLP LAF AL+++W P L+ AVL L G+++A+V+HAEV+A +VGE Sbjct 8 KWLHWTRVLPILAFAALIVSWIYH--PTAALVLAVLTILLIGSIIASVHHAEVIAQKVGE 65 Query 60 PFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLR 119 PFGSLVLAVAVT IEV LI+ LM SG +ATLARDTVFAAVMIT NGI GLSL + + R Sbjct 66 PFGSLVLAVAVTVIEVGLILTLMASG-KGSATLARDTVFAAVMITINGIMGLSLTVSAAR 124 Query 120 YGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFL 179 + + F+ GSG ALATVT LA + LVLP FT S P +P QL FAG ASL LY LF+ Sbjct 125 HSTSRFSALGSGGALATVTALAGICLVLPRFTVSDPSPSYTPSQLAFAGVASLVLYGLFI 184 Query 180 FTQTVRHRDFFLPVAQKGA-VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVI 238 QT RHR FLP+ + G ++ D + P+T A L SLG LL+ALVAVVGLAK+ SP I Sbjct 185 AAQTGRHRSSFLPIDEDGMPIDTDDDSWTPTTAATLRSLGFLLIALVAVVGLAKILSPTI 244 Query 239 EEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPT 298 E V+AAG P FVGV+IA +VL PE+LAA RAARQ R+Q SLNLA GSAMASIGLTIPT Sbjct 245 EAGVAAAGLPPGFVGVIIALVVLAPESLAAVRAARQNRVQVSLNLALGSAMASIGLTIPT 304 Query 299 IALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +A+A +W G LGLG+ Q+VLLV++V++++LT+ PGRATRLQG VHLV+LAAY+FLA Sbjct 305 LAVAMIWFPGEFYLGLGSTQIVLLVMSVLLAMLTIAPGRATRLQGGVHLVILAAYIFLAA 364 Query 359 VP 360 P Sbjct 365 NP 366 >gi|88856655|ref|ZP_01131311.1| Probable ionic transporter integral membrane protein chaA [marine actinobacterium PHSC20C1] gi|88814116|gb|EAR23982.1| Probable ionic transporter integral membrane protein chaA [marine actinobacterium PHSC20C1] Length=363 Score = 383 bits (983), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 229/361 (64%), Positives = 285/361 (79%), Gaps = 4/361 (1%) Query 2 LKR-VPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEP 60 LKR VP+ V P L + L L+WG ++ P+ + AV+LA VL+AV+HAEV+A +VGEP Sbjct 5 LKRAVPFAV--PILGALTLALSWGLELNPLGAGVIAVVLAATVLSAVHHAEVIAHKVGEP 62 Query 61 FGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRY 120 FGSL+LAVAVT IEVALI+ L++SG D +ATLARDTVFAAVMIT NGI G+SL +G +++ Sbjct 63 FGSLILAVAVTVIEVALIITLVLSGDDGSATLARDTVFAAVMITMNGILGISLAVGGIKH 122 Query 121 GVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLF 180 GV FN G+GA LA +T+LA L LVLP+FTT + SPGQL FA ASL +Y +F+ Sbjct 123 GVIRFNSEGAGALLAVITSLAVLGLVLPSFTTGAPEGQYSPGQLAFAAIASLAIYGMFVG 182 Query 181 TQTVRHRDFFLPVAQKGA-VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIE 239 TQTVRHRDFFLPVA G +E D HAD P+ + A SLGLL++ALV VVGLAKVESP IE Sbjct 183 TQTVRHRDFFLPVAPNGKNLEPDDHADAPTAKQAWASLGLLVLALVTVVGLAKVESPSIE 242 Query 240 EVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTI 299 V++ A P SFVGVVIA LVLLPE++AA AAR R+QTS+NLA+GSA+ASIGLTIP I Sbjct 243 AVIAFAQLPPSFVGVVIALLVLLPESIAAVNAARANRIQTSINLAFGSAVASIGLTIPAI 302 Query 300 ALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVV 359 A+AS+W+ GPL LGLGA Q+VLL+LTV+VS+L+VVPGRATRLQG VHLV+ AA++FL++ Sbjct 303 AIASIWIPGPLNLGLGATQIVLLMLTVIVSILSVVPGRATRLQGGVHLVIFAAFIFLSMF 362 Query 360 P 360 P Sbjct 363 P 363 >gi|309811248|ref|ZP_07705039.1| putative calcium/proton exchanger [Dermacoccus sp. Ellin185] gi|308434788|gb|EFP58629.1| putative calcium/proton exchanger [Dermacoccus sp. Ellin185] Length=369 Score = 382 bits (982), Expect = 4e-104, Method: Compositional matrix adjust. Identities = 235/356 (67%), Positives = 278/356 (79%), Gaps = 2/356 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT P L V L TWG+ + VV +L L GAVLAAV+HAEV+AA+VGEP GS+VL Sbjct 14 WTTWAPILGAVVLAATWGRSLPGVVAVLVTAALFGAVLAAVHHAEVIAAKVGEPLGSIVL 73 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEV LIV LM SG D TLARDTVFAA+MIT NGIAGL + LG+ R G+ FN Sbjct 74 AVAVTVIEVGLIVTLMASGKDGVETLARDTVFAALMITINGIAGLCIFLGAGRRGLARFN 133 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P GS AALA V T+A L LVLPTFT+++SGPE SP QL FA +S+G+Y +F+ TQTVRH Sbjct 134 PEGSAAALAGVVTVAGLCLVLPTFTSARSGPEFSPSQLAFAAISSIGVYAMFVLTQTVRH 193 Query 187 RDFFLPVAQKGA--VEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSA 244 RDFF+PV + G ++D+H PSTRAAL+SLGLL+VALVAVVGLAKV SP IE+ V A Sbjct 194 RDFFVPVDRAGKPLDDEDAHGPAPSTRAALVSLGLLVVALVAVVGLAKVLSPSIEQAVDA 253 Query 245 AGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASL 304 AGFPQSFVGVVIA +VLLPETLAAA+ AR GR+Q SLNLAYGSAMASIGLTIPT+A S Sbjct 254 AGFPQSFVGVVIALVVLLPETLAAAKYARAGRVQNSLNLAYGSAMASIGLTIPTLAALSP 313 Query 305 WLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +LS PL+LGLG++ +VLLVL++VV +LT+V GRATR G + LVLL AY+FLA P Sbjct 314 FLSSPLELGLGSMHIVLLVLSLVVGILTIVQGRATRFSGWILLVLLFAYVFLAANP 369 >gi|111017285|ref|YP_700257.1| sodium calcium/ proton antiporter [Rhodococcus jostii RHA1] gi|110816815|gb|ABG92099.1| sodium calcium/ proton antiporter, CacA family protein [Rhodococcus jostii RHA1] Length=319 Score = 378 bits (971), Expect = 7e-103, Method: Compositional matrix adjust. Identities = 228/319 (72%), Positives = 258/319 (81%), Gaps = 1/319 (0%) Query 43 VLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVM 102 +LAAV+HAEVVA +VGEPFGSL+LAVAVT IEV LIV LM+SGG A+LARDTVFAAVM Sbjct 1 MLAAVHHAEVVAHKVGEPFGSLILAVAVTVIEVGLIVTLMISGGPATASLARDTVFAAVM 60 Query 103 ITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPG 162 +T NGI GLSL +G+ RYGV LFN G+GAALATV +LATLSLVLPTFTTS+ GPE S Sbjct 61 LTVNGIMGLSLFVGARRYGVALFNAEGTGAALATVASLATLSLVLPTFTTSRPGPEFSSA 120 Query 163 QLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGAVE-DDSHADPPSTRAALLSLGLLL 221 QLIFA ASL LY +F+ TQT HR FFLPV V +D +A PPS R A +SL LL+ Sbjct 121 QLIFAAVASLVLYGMFVLTQTGPHRHFFLPVIPDEPVAVEDRNAAPPSGRVAGMSLALLV 180 Query 222 VALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSL 281 +AL AVVGLAKVESP IE+ V AG PQS VGVVIA LVLLPETLAA RAA++ R+Q SL Sbjct 181 LALCAVVGLAKVESPTIEDAVEDAGLPQSIVGVVIALLVLLPETLAAVRAAQRNRIQISL 240 Query 282 NLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRL 341 NLA GSAMASIGLTIP IA+AS+WL GPL LGLG Q+VLL +TVVV +LTVVPGRATRL Sbjct 241 NLALGSAMASIGLTIPAIAVASIWLDGPLLLGLGPTQVVLLAITVVVGMLTVVPGRATRL 300 Query 342 QGEVHLVLLAAYLFLAVVP 360 QG VHLVLLAAY+FL+V P Sbjct 301 QGGVHLVLLAAYVFLSVNP 319 >gi|330468539|ref|YP_004406282.1| sodium/calcium exchanger membrane region [Verrucosispora maris AB-18-032] gi|328811510|gb|AEB45682.1| sodium/calcium exchanger membrane region [Verrucosispora maris AB-18-032] Length=365 Score = 378 bits (971), Expect = 7e-103, Method: Compositional matrix adjust. Identities = 237/355 (67%), Positives = 280/355 (79%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WTV +P A V L LTW +++ ++ ++ + LAGAVLAAV+HAEVVA +VGEP+GSLVL Sbjct 11 WTVSVPIAALVVLALTWNQKLDGIMVVIVGLFLAGAVLAAVHHAEVVAHKVGEPYGSLVL 70 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+SGG+ +LARDTVFAAVMIT NGI GLSLL+G+LR + +FN Sbjct 71 AVAVTVIEVALIVTLMISGGEKTQSLARDTVFAAVMITCNGILGLSLLIGALRRRLAVFN 130 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P G+G ALATV TLATLSLV+PTFT ++GP+ SP QL FA SL LY LF+ QT RH Sbjct 131 PEGTGGALATVATLATLSLVVPTFTIGRAGPQFSPAQLTFAAVVSLALYALFVMVQTGRH 190 Query 187 RDFFLPVAQKG-AVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RD+FLPV +G + ++ HADPPSTR AL+SLGLLLVALVAVVG AK SP IE V+A Sbjct 191 RDYFLPVGSEGETLPEEVHADPPSTRQALISLGLLLVALVAVVGDAKSVSPAIEAGVAAV 250 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 P +FVGV+IA LVLLPETLAAARAAR+ R+Q SLNL+ GSAMASIGLTIP IA+AS+W Sbjct 251 NLPPAFVGVIIALLVLLPETLAAARAARRDRVQISLNLSLGSAMASIGLTIPAIAIASIW 310 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 L GPL LGLG Q+ LL LTV+ VLTVVPGRAT LQG VHLVL AA++FLA P Sbjct 311 LEGPLLLGLGGTQVTLLALTVITGVLTVVPGRATLLQGGVHLVLFAAFVFLAASP 365 >gi|238064521|ref|ZP_04609230.1| ionic transporter integral membrane protein [Micromonospora sp. ATCC 39149] gi|237886332|gb|EEP75160.1| ionic transporter integral membrane protein [Micromonospora sp. ATCC 39149] Length=368 Score = 377 bits (969), Expect = 1e-102, Method: Compositional matrix adjust. Identities = 257/357 (72%), Positives = 284/357 (80%), Gaps = 3/357 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT+ +P LA V L LTWG+++ P+V + A LAGAVLAAV+HAEVVA +VGEPFGSLVL Sbjct 12 WTLTVPVLAVVILALTWGRELPPLVVGVVATFLAGAVLAAVHHAEVVAHKVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+SGGD LARDTVFAAVMIT NGI GLSLLLG+LR V +FN Sbjct 72 AVAVTVIEVALIVTLMISGGDKTQALARDTVFAAVMITCNGILGLSLLLGALRRRVAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P G+G ALATV TLATLSLV+PTFTTS+ GPE SP QL FA ASL LY LF+ QT RH Sbjct 132 PEGTGGALATVATLATLSLVVPTFTTSRPGPEFSPPQLAFAAVASLALYGLFVLVQTGRH 191 Query 187 RDFFLPVAQKGAV---EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 RD+FLPV G V + D HADPPS AAL SL +LLVAL+AVVGLAK+ SP IE VS Sbjct 192 RDYFLPVTADGTVADADADGHADPPSAGAALASLVMLLVALIAVVGLAKMVSPAIEAGVS 251 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 AA PQSFVGVVIA LVLLPETLAAARAAR+ R+Q SLNLA GSAMASIGLTIP IA+AS Sbjct 252 AANLPQSFVGVVIALLVLLPETLAAARAARRDRVQISLNLALGSAMASIGLTIPAIAIAS 311 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +WL GPL LGLG QL LL LTVV VLTVVPGRAT LQG VHLVLLAA++FLA P Sbjct 312 IWLDGPLLLGLGGTQLALLALTVVAGVLTVVPGRATLLQGGVHLVLLAAFVFLAASP 368 >gi|329940830|ref|ZP_08290110.1| ionic transporter [Streptomyces griseoaurantiacus M045] gi|329300124|gb|EGG44022.1| ionic transporter [Streptomyces griseoaurantiacus M045] Length=366 Score = 377 bits (969), Expect = 1e-102, Method: Compositional matrix adjust. Identities = 243/355 (69%), Positives = 283/355 (80%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT V+P LA V LVLTW +++ V + ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTTVVPLLAVVLLVLTWKRELPGPVVAVVTLVLAGAVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM GGD +ATLARDTVFAAVMIT NG+ GLSLL+GSLR+G +FN Sbjct 72 AVAVTVIEVALIVTLMADGGDKSATLARDTVFAAVMITCNGVVGLSLLVGSLRHGTAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 P G+GAALATV TLATLSLVLPTFTTS+ GPE S QL+FA +SL LY LF+ TQTVRH Sbjct 132 PEGTGAALATVATLATLSLVLPTFTTSKRGPEFSTPQLVFAAVSSLILYALFVTTQTVRH 191 Query 187 RDFFLPVAQKGAV-EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 R++FLP+ ++G V + HA PS R + +SL LL ALV VVGLAK SP +E V+AA Sbjct 192 REYFLPITRQGEVIRAEDHASRPSVRESWISLTLLGAALVGVVGLAKGVSPTLESGVAAA 251 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G PQ+ VGV IA LVLLPET+AA R AR+ R+QTSLNLA GSAMASIGLTIP +A AS+W Sbjct 252 GLPQAVVGVAIALLVLLPETIAALRQARRDRVQTSLNLALGSAMASIGLTIPAVAAASVW 311 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 L+GPL+LGL + +VLL+LTVVVS LTVVPGRAT LQG VHLVL AAYL LA+ P Sbjct 312 LAGPLELGLAPLHMVLLLLTVVVSSLTVVPGRATPLQGGVHLVLFAAYLELAINP 366 >gi|29832819|ref|NP_827453.1| ionic transporter integral membrane protein [Streptomyces avermitilis MA-4680] gi|29609940|dbj|BAC73988.1| putative ionic transporter integral membrane protein [Streptomyces avermitilis MA-4680] Length=366 Score = 377 bits (968), Expect = 1e-102, Method: Compositional matrix adjust. Identities = 248/355 (70%), Positives = 282/355 (80%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT V+P A V L LTWG+ + V L ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 12 WTAVVPVAAIVLLALTWGRDLPGAVVALVTLVLAGAVLAAVHHAEVVAHRVGEPFGSLVL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM GG +ATLARDTVFAAVMIT NGI G+ LL+ SLR+G+ +FN Sbjct 72 AVAVTIIEVALIVTLMADGGGKSATLARDTVFAAVMITCNGIVGICLLVASLRHGLAVFN 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+GAALATV TLATLSLV PTFTTS+ GPE S QL FA ASL LY LF+ TQTVRH Sbjct 132 AEGTGAALATVATLATLSLVFPTFTTSKPGPEFSTTQLTFAALASLILYGLFVTTQTVRH 191 Query 187 RDFFLPVAQKGAVED-DSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 RD+FLP+ + G V D ++HAD P+ R A +SLGLL +ALV VVGLAK SP IE V AA Sbjct 192 RDYFLPITRHGEVIDAETHADAPTARTAGISLGLLGLALVGVVGLAKGVSPTIESGVEAA 251 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G PQS VGV+IA LVLLPET+AA R+AR+ R+QTSLNLA GSAMASIGLTIP +ALAS+W Sbjct 252 GMPQSVVGVIIALLVLLPETIAALRSARRDRVQTSLNLALGSAMASIGLTIPAVALASVW 311 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LSGPL LGLG+ +VLL+LTVVVS LTVVPGRAT LQG VHLV+ AAYL LAV P Sbjct 312 LSGPLVLGLGSTHMVLLLLTVVVSSLTVVPGRATPLQGGVHLVVFAAYLELAVNP 366 >gi|344997893|ref|YP_004800747.1| sodium/calcium exchanger membrane region [Streptomyces sp. SirexAA-E] gi|344313519|gb|AEN08207.1| sodium/calcium exchanger membrane region [Streptomyces sp. SirexAA-E] Length=407 Score = 376 bits (966), Expect = 3e-102, Method: Compositional matrix adjust. Identities = 238/355 (68%), Positives = 277/355 (79%), Gaps = 1/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WTV +P +A + L L+WG+ +GPV L A+ LAG+VLAAV+HAEVVA RVG+P+GSL+L Sbjct 53 WTVAVPVIAALVLALSWGRDLGPVAVALIALCLAGSVLAAVHHAEVVAHRVGDPYGSLIL 112 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+ GG A++LARDTVFAAVMIT NGI G+ LL+G++R V +FN Sbjct 113 AVAVTVIEVALIVTLMIDGGPKASSLARDTVFAAVMITCNGIVGICLLVGAVRSRVAVFN 172 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+GAALATV TLATLSLVLPTFT + GPE SP QL FA ASL LY LF+ QTVRH Sbjct 173 AEGTGAALATVATLATLSLVLPTFTIGKRGPEFSPAQLGFAAVASLLLYGLFVAVQTVRH 232 Query 187 RDFFLPVAQKGAVE-DDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 R++FLP+ Q G + DD + P R LSL +LLVALVAVVG AK SP +E V A Sbjct 233 REYFLPLTQDGRLRPDDDPSALPGRRETTLSLIMLLVALVAVVGNAKSVSPAVESGVDAV 292 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G PQ+ VGVVIA LVLLPETLAA RAAR+ R+QTSLNLA GSAMASIGLTIPTIALAS+W Sbjct 293 GMPQAVVGVVIALLVLLPETLAAVRAARRERVQTSLNLALGSAMASIGLTIPTIALASIW 352 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 L GPL LGLGA +VLLVLTVVV LTVVPGRAT LQG VHL + AA++FLA+ P Sbjct 353 LDGPLHLGLGATHMVLLVLTVVVGALTVVPGRATLLQGGVHLAIFAAFVFLAISP 407 >gi|302561247|ref|ZP_07313589.1| cation/proton antiporter [Streptomyces griseoflavus Tu4000] gi|302478865|gb|EFL41958.1| cation/proton antiporter [Streptomyces griseoflavus Tu4000] Length=366 Score = 372 bits (955), Expect = 6e-101, Method: Compositional matrix adjust. Identities = 235/342 (69%), Positives = 273/342 (80%), Gaps = 2/342 (0%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 WT ++P A V LVLTWG+++ + + ++LAGAVLAAV+HAEVVA RVGEPFGSLVL Sbjct 11 WTTLVPVFAVVLLVLTWGRELPGWIVAVVTLILAGAVLAAVHHAEVVAHRVGEPFGSLVL 70 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 AVAVT IEVALIV LM+ GGD +ATLARDTVFAAVMIT NGI GLSLL+GSLR+G +FN Sbjct 71 AVAVTVIEVALIVTLMIDGGDKSATLARDTVFAAVMITVNGILGLSLLVGSLRHGTAVFN 130 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 G+GAALATV TLATLSLVLPTFTTS+ GPE S QL FA +SL LY LF+ TQTVRH Sbjct 131 SEGTGAALATVATLATLSLVLPTFTTSKPGPEFSTVQLTFAAVSSLILYALFVATQTVRH 190 Query 187 RDFFLPVAQKG--AVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSA 244 RD+FLP+ ++ A + HA+ P+TR AL+SLGLL +AL+ VVGLAK SP IE V A Sbjct 191 RDYFLPIVKQSEKASPVEEHAEAPTTRVALISLGLLGLALIGVVGLAKGVSPTIESGVDA 250 Query 245 AGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASL 304 AG P S VGVVIA LVLLPET+AA RAAR+ ++QTS+NLA GSAMASIGLTIP +ALASL Sbjct 251 AGLPHSVVGVVIALLVLLPETIAAVRAARRNQVQTSMNLALGSAMASIGLTIPAVALASL 310 Query 305 WLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVH 346 WL+GPL LGLG +VLL LT+VV LTVVPGRAT LQG VH Sbjct 311 WLTGPLVLGLGNTHMVLLALTMVVGALTVVPGRATPLQGGVH 352 >gi|302870373|ref|YP_003839010.1| sodium/calcium exchanger membrane subunit [Micromonospora aurantiaca ATCC 27029] gi|315503350|ref|YP_004082237.1| sodium/calcium exchanger membrane subunit [Micromonospora sp. L5] gi|302573232|gb|ADL49434.1| sodium/calcium exchanger membrane region [Micromonospora aurantiaca ATCC 27029] gi|315409969|gb|ADU08086.1| sodium/calcium exchanger membrane region [Micromonospora sp. L5] Length=367 Score = 370 bits (951), Expect = 2e-100, Method: Compositional matrix adjust. Identities = 252/360 (70%), Positives = 287/360 (80%), Gaps = 7/360 (1%) Query 7 WTVVLPSLAFVALVLTWGKQI-GPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WT V P +A + LV+TWG+++ GP++ + A LLA AVLAAV+HAEVVA +VGEPFGSLV Sbjct 9 WTTVAPLVAVLVLVMTWGRELPGPLI-FVVAALLAAAVLAAVHHAEVVAHKVGEPFGSLV 67 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LAVAVT IEV LIV LM+SGGD LARDTVFAA+MIT NGI GLSLLLG+LR V +F Sbjct 68 LAVAVTVIEVGLIVTLMISGGDKTQALARDTVFAAIMITCNGILGLSLLLGALRRQVAVF 127 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 NP G+G ALATV TLATLSLV+PTFTTS+ GPE SP QL FA ASL LY+LF+ QT R Sbjct 128 NPEGTGGALATVATLATLSLVVPTFTTSRPGPEFSPAQLAFAAVASLALYLLFVMVQTGR 187 Query 186 HRDFFLPVAQKGAV--ED---DSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEE 240 HRD+FLPV Q+G++ ED D HA+PPSTR AL SL LL+VALVAVVG AK SP IE Sbjct 188 HRDYFLPVTQEGSILAEDKNGDGHAEPPSTRTALASLALLVVALVAVVGDAKTISPAIET 247 Query 241 VVSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIA 300 V AA PQ+FVGVVIA LVLLPETLAAARAAR+ R+Q SLNLA GSAMASIGLTIP IA Sbjct 248 AVGAANLPQAFVGVVIALLVLLPETLAAARAARRDRVQISLNLALGSAMASIGLTIPAIA 307 Query 301 LASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 +AS+WL GPL LGLG Q+ LL LT V +VLTVVPGRAT LQG VHLVLLAA++FLA P Sbjct 308 IASIWLDGPLVLGLGGTQMTLLALTAVAAVLTVVPGRATVLQGGVHLVLLAAFVFLAASP 367 >gi|328880344|emb|CCA53583.1| Calcium or proton antiporter [Streptomyces venezuelae ATCC 10712] Length=365 Score = 364 bits (934), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 238/355 (68%), Positives = 277/355 (79%), Gaps = 2/355 (0%) Query 7 WTVVLPSLAFVALVLTWGKQI-GPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLV 65 WT P +A +ALV WG+ + G VGL+A L+A AVLAAV+HAEV+A RVGEP+GSLV Sbjct 12 WTTWGPVVAALALVAAWGRDLPGFAVGLIALCLIA-AVLAAVHHAEVIAHRVGEPYGSLV 70 Query 66 LAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLF 125 LAVAVT IEV LIV+LM GG+ +T ARDTVFAAVMIT NGI GLSL + +LR V +F Sbjct 71 LAVAVTVIEVGLIVSLMAGGGEKTSTYARDTVFAAVMITCNGIVGLSLTVAALRNRVAVF 130 Query 126 NPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVR 185 N GSG ALATV TLAT++LVLPTFTTS GPE S QL FA ASL LY +F+ QTVR Sbjct 131 NAEGSGGALATVCTLATMTLVLPTFTTSHPGPEFSSAQLAFAAVASLCLYAVFVGVQTVR 190 Query 186 HRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAA 245 HRD+FLPV + G D HADPP+ R A SLGLL+VALVAVVG AK+ SP IE+ V +A Sbjct 191 HRDYFLPVPRPGQDSADDHADPPTRRDAWTSLGLLVVALVAVVGNAKLISPTIEDGVQSA 250 Query 246 GFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLW 305 G P++ VGVVIA +VLLPETLAA RAAR+ R+QTSLNLAYGSA+ASIGLTIP IALAS+W Sbjct 251 GLPKAVVGVVIALMVLLPETLAAVRAARRDRVQTSLNLAYGSAIASIGLTIPAIALASIW 310 Query 306 LSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 LSGPL LGLG + +VLLVLT VVS LTVVPGRAT LQG VHL + AA++FL+ P Sbjct 311 LSGPLVLGLGPLHMVLLVLTGVVSALTVVPGRATLLQGGVHLAMFAAFVFLSFSP 365 >gi|54023079|ref|YP_117321.1| putative transporter [Nocardia farcinica IFM 10152] gi|54014587|dbj|BAD55957.1| putative transporter [Nocardia farcinica IFM 10152] Length=364 Score = 355 bits (910), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 247/359 (69%), Positives = 276/359 (77%), Gaps = 2/359 (0%) Query 4 RVPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGS 63 R WTV +P LA V L TWG+ + V ++ A L GAVL+AV HAEVVA RVGEPFG+ Sbjct 6 RDRWTVFVPLLAAVVLAATWGRSLPSVGVVVVAAFLIGAVLSAVYHAEVVAERVGEPFGA 65 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLAVAVT IEVALIV LM+SGG+ +ATLARDTVFAAVMIT NGI GL+LL+ +LR V Sbjct 66 LVLAVAVTVIEVALIVTLMISGGEKSATLARDTVFAAVMITCNGIFGLALLVAALRRRVA 125 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 FN G+GAALATV TLATLSLVLPTFT+S GPE S QL FA ASL LY LF+ QT Sbjct 126 EFNAEGTGAALATVATLATLSLVLPTFTSSVPGPEFSTPQLAFAAIASLSLYGLFVMVQT 185 Query 184 VRHRDFFLPVAQKGAV--EDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEV 241 VRHRD FLP Q V +DD H + PSTRAALLSL LLL+AL VVGLAKV SP IE Sbjct 186 VRHRDDFLPPVQADGVVTDDDLHDERPSTRAALLSLALLLLALTGVVGLAKVVSPSIESA 245 Query 242 VSAAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIAL 301 V+ AG P + VGVVIA LVLLPETLAA RAAR+ RLQ SLNLA GSAMASIGLTIP IA+ Sbjct 246 VATAGMPHAAVGVVIALLVLLPETLAAVRAARRDRLQISLNLALGSAMASIGLTIPVIAV 305 Query 302 ASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 A++WL GPL LGLGA Q+VLL LTVVV VLTVVPGRAT LQG VHL L +A++FLA P Sbjct 306 ATIWLPGPLILGLGATQMVLLALTVVVGVLTVVPGRATLLQGGVHLALFSAFVFLAASP 364 >gi|284034771|ref|YP_003384702.1| sodium/calcium exchanger membrane region [Kribbella flavida DSM 17836] gi|283814064|gb|ADB35903.1| sodium/calcium exchanger membrane region [Kribbella flavida DSM 17836] Length=407 Score = 353 bits (907), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 225/396 (57%), Positives = 272/396 (69%), Gaps = 42/396 (10%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVGEPFGSLVL 66 W++ +P LA V LVL+WG+ +G + +L L AV+AAV+HAEVVA RVGEPFG+L+L Sbjct 12 WSLAVPPLALVVLVLSWGRDLGAFLVILVCAGLGAAVIAAVHHAEVVAHRVGEPFGTLIL 71 Query 67 AVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVTLFN 126 A+AVT IEVALIV LM SGGD AA+LARDTVFAAVMIT NGI GLSL++GSLR+ F Sbjct 72 ALAVTVIEVALIVTLMASGGDKAASLARDTVFAAVMITCNGILGLSLVVGSLRHRTQQFR 131 Query 127 PHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRH 186 H SG+ALA +T L TLSLVLPTFTTS G S QL FAG SL +Y +F+F QT+RH Sbjct 132 VHASGSALAVMTALVTLSLVLPTFTTSTPGATFSGAQLAFAGVVSLVMYGVFVFVQTIRH 191 Query 187 RDFFLP--------------------------VAQKGAVEDD----------------SH 204 RD+FLP VA V DD +H Sbjct 192 RDYFLPVEPAQQPAAESAAAHKAAAERSADAAVAHDEMVADDEVVKAGDELEEDEDHETH 251 Query 205 ADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATLVLLPE 264 A PST+ AL SL LL + L+AVVGLAK SP +E V +AG P + VGV+IA LVLLPE Sbjct 252 AAAPSTKVALSSLVLLFLCLLAVVGLAKTVSPKLESAVESAGAPLAVVGVIIALLVLLPE 311 Query 265 TLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVL 324 T+AA RAA + RLQTSLNLA GSA+ASIGLTIP IA+AS+WL+GPL LGLG ++VL L Sbjct 312 TVAAVRAALRNRLQTSLNLALGSALASIGLTIPAIAVASIWLTGPLVLGLGGKEMVLFAL 371 Query 325 TVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAVVP 360 TVVVS+LT+ GRAT LQG VHL++ +++LFLAV P Sbjct 372 TVVVSMLTLATGRATLLQGAVHLMIFSSFLFLAVSP 407 >gi|315498735|ref|YP_004087539.1| sodium/calcium exchanger membrane protein [Asticcacaulis excentricus CB 48] gi|315416747|gb|ADU13388.1| sodium/calcium exchanger membrane region [Asticcacaulis excentricus CB 48] Length=369 Score = 338 bits (866), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 186/326 (58%), Positives = 240/326 (74%), Gaps = 1/326 (0%) Query 35 AAVLLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLAR 94 AAV++ G VLAAV+HAEVVA RVGEPFG+LVLA+AVT IEV+LIV+LM+SG D ATLAR Sbjct 45 AAVIMMGCVLAAVHHAEVVAHRVGEPFGTLVLAIAVTIIEVSLIVSLMLSGSGDTATLAR 104 Query 95 DTVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQ 154 DTVFAA+MI NGI G+ LL+G +R+ F G +AL + +A+LSLVLP FT+S Sbjct 105 DTVFAAIMIIMNGIVGICLLVGGVRHHEQRFVLKGVSSALCVLAAMASLSLVLPNFTSSV 164 Query 155 SGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQKGAVEDDSHADPPSTRAAL 214 GP SP QLIF SL LY F+ QTVRHRD+FLP + +G ++ D+HA+PP+ + L Sbjct 165 PGPFFSPSQLIFVAVVSLILYGAFVLVQTVRHRDYFLP-SGEGDLKPDAHAEPPTLKETL 223 Query 215 LSLGLLLVALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQ 274 ++ G+L+VAL VV LAK SP +E+ V AG P + VGV+IA LVL PE+L+A +AAR+ Sbjct 224 IAFGVLIVALAGVVLLAKSLSPHVEKAVVGAGLPLAVVGVLIAALVLAPESLSAIKAARR 283 Query 275 GRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVV 334 RLQTSLNLA GSA+A+IGLTIP +A+ S+ + PL LGL +VLL+L+ VVS+ ++ Sbjct 284 NRLQTSLNLALGSALATIGLTIPAVAVLSVIMGWPLSLGLDTKSMVLLLLSFVVSIFSLG 343 Query 335 PGRATRLQGEVHLVLLAAYLFLAVVP 360 GR T LQG HLV+ A YLF+ VVP Sbjct 344 TGRTTVLQGVTHLVIFATYLFVTVVP 369 >gi|256395890|ref|YP_003117454.1| sodium/calcium exchanger membrane region [Catenulispora acidiphila DSM 44928] gi|256362116|gb|ACU75613.1| sodium/calcium exchanger membrane region [Catenulispora acidiphila DSM 44928] Length=392 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 220/386 (57%), Positives = 259/386 (68%), Gaps = 28/386 (7%) Query 3 KRVP----WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLAAVNHAEVVAARVG 58 +R+P W+ +P LA V L TWG+ + P V + A LL GAVLAAV+HAEVVA RVG Sbjct 7 QRLPAWAVWSNAVPVLAGVLLAFTWGRDMPPWVVAVIAALLFGAVLAAVHHAEVVAHRVG 66 Query 59 EPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSL 118 EPFGSLVLAVAVT IEVALI+ +M + G A LARDTVFAAVMIT NGIAGL LLLG+L Sbjct 67 EPFGSLVLAVAVTVIEVALIITMMSAKGAKGAGLARDTVFAAVMITCNGIAGLCLLLGAL 126 Query 119 RYGVTLFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLF 178 + G+ LFN G+ + TLA L+LVLPTFTTSQ GPE + QL FA AS+ +Y LF Sbjct 127 KRGLALFNADGTSTVFGAIITLAGLTLVLPTFTTSQPGPEFNDTQLTFAALASIAVYGLF 186 Query 179 LFTQTVRHRDFFLPVAQ------------------------KGAVEDDSHADPPSTRAAL 214 + TVRHR +LPV + G ED + P+ R AL Sbjct 187 ISALTVRHRPDYLPVGRDGGGAGSGSDSDAGFESDTGFENDTGFDEDGYEGERPTARQAL 246 Query 215 LSLGLLLVALVAVVGLAKVESPVIEEVVSAAGFPQSFVGVVIATLVLLPETLAAARAARQ 274 +SLGLL++ALVAVVGL K SP IE V AG P S VGVVIA +VLLPE +AA RAA++ Sbjct 247 ISLGLLVLALVAVVGLGKGVSPTIERGVDRAGLPASVVGVVIALMVLLPEAIAAVRAAQR 306 Query 275 GRLQTSLNLAYGSAMASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVSVLTVV 334 +QTSLNLA GSAMASIGLTIP IA+A++WLS PL LGL A +VLL +TV V LT V Sbjct 307 DEVQTSLNLALGSAMASIGLTIPAIAVATVWLSTPLLLGLDASHMVLLAMTVAVGTLTFV 366 Query 335 PGRATRLQGEVHLVLLAAYLFLAVVP 360 GRAT +QG HLVL A YL LAV P Sbjct 367 RGRATLVQGGAHLVLCAGYLVLAVSP 392 >gi|167584319|ref|ZP_02376707.1| sodium/calcium exchanger membrane region [Burkholderia ubonensis Bu] Length=362 Score = 325 bits (834), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 200/355 (57%), Positives = 253/355 (72%), Gaps = 8/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVL---LAGAVLAAVNHAEVVAARVGEPFGS 63 WT+ P A++ L L+ ++ P GL+ A+ LAG+V AAV+HAEVVA RVGEPFG+ Sbjct 11 WTLWAPLAAWLVLALS---RVVPAEGLVIALFAAALAGSVFAAVHHAEVVAHRVGEPFGT 67 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLAVAVT IEVALIV++M+ G + + LARDTVFAAVMI NGI GL LL+G+ R+G Sbjct 68 LVLAVAVTVIEVALIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVGAWRHGEQ 127 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP S QL FAG +SL LY +F+F QT Sbjct 128 DFQGRGASKALAVLASLSVLSLVMPNYLSAAPGPLFSRSQLAFAGVSSLVLYGVFVFVQT 187 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL A + + HA PPS+R AL+SL L V+LVAVV LAK+ SP +E V Sbjct 188 VRHRDYFL--ADHDSANESVHAAPPSSRTALVSLLFLFVSLVAVVLLAKLLSPAVEHAVL 245 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 246 QLGLPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPTVAAVF 305 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W+ PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL+V Sbjct 306 IWVGQPLTLGIGAMETVLLSLTLLVSTLTLSAGRTTVLHGVVHLSLFAAYLFLSV 360 >gi|170702752|ref|ZP_02893610.1| sodium/calcium exchanger membrane region [Burkholderia ambifaria IOP40-10] gi|170132345|gb|EDT00815.1| sodium/calcium exchanger membrane region [Burkholderia ambifaria IOP40-10] Length=362 Score = 321 bits (823), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 198/355 (56%), Positives = 250/355 (71%), Gaps = 8/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVL---LAGAVLAAVNHAEVVAARVGEPFGS 63 WT+ P A++ L L+ ++ P GL+ AVL LAGAV AAV+HAEVVA RVGEPFG+ Sbjct 11 WTLWAPLAAWLVLALS---RVVPAEGLVIAVLATALAGAVFAAVHHAEVVAHRVGEPFGT 67 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLAVAVT IEVALIV++M+ G + + LARDTVFAAVMI NGI GL LL+G+ ++G Sbjct 68 LVLAVAVTVIEVALIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVGAWKHGEQ 127 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + + GP S QL FAG +SL LY F+F QT Sbjct 128 DFQGRGASKALAVLASLSVLSLVMPNYLNAAPGPFFSKSQLAFAGVSSLVLYGAFVFVQT 187 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL + + HA PP+ R A++SL LL +LVAVV LAK+ SP +E V Sbjct 188 VRHRDYFL--TAHDSANESVHAAPPTGRTAVISLVLLFASLVAVVLLAKLLSPAVEHAVM 245 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 246 KLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPTVAAVF 305 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W+ PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 306 IWVGQPLTLGIGAMETVLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSI 360 >gi|53717047|ref|YP_105842.1| calcium/proton exchanger [Burkholderia mallei ATCC 23344] gi|67640317|ref|ZP_00439128.1| calcium/cation antiporter (CaCA) family [Burkholderia mallei GB8 horse 4] gi|124382423|ref|YP_001024255.1| calcium/cation antiporter [Burkholderia mallei NCTC 10229] 13 more sequence titles Length=361 Score = 314 bits (805), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 196/355 (56%), Positives = 247/355 (70%), Gaps = 9/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVL---AAVNHAEVVAARVGEPFGS 63 WT+V P A++ L L+ ++ P G A + A +AV+HAEVVA RVGEPFG+ Sbjct 11 WTLVAPLAAWLVLALS---RVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGT 67 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLA+AVT IEVALIV++M+S G + A LARDTVFAAVMI NGI GL LL+G R+G Sbjct 68 LVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQ 127 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP LS QL FAG +SL LY +F+F QT Sbjct 128 DFQGRGAAKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQT 187 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL G+ ++ HA PPS R AL S+ L V+LVAVV LAK+ SP +E V Sbjct 188 VRHRDYFL---IDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVL 244 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 245 RLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVF 304 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 305 IWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSI 359 >gi|167906382|ref|ZP_02493587.1| calcium/proton exchanger [Burkholderia pseudomallei NCTC 13177] Length=361 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 196/355 (56%), Positives = 247/355 (70%), Gaps = 9/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVL---AAVNHAEVVAARVGEPFGS 63 WT+V P A++ L L+ ++ P G A + A +AV+HAEVVA RVGEPFG+ Sbjct 11 WTLVAPLAAWLVLALS---RVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGT 67 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLA+AVT IEVALIV++M+S G + A LARDTVFAAVMI NGI GL LL+G R+G Sbjct 68 LVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQ 127 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP LS QL FAG +SL LY +F+F QT Sbjct 128 DFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGMSSLVLYGVFVFVQT 187 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL G+ ++ HA PPS R AL S+ L V+LVAVV LAK+ SP +E V Sbjct 188 VRHRDYFL---IDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVL 244 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 245 RLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVF 304 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 305 IWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSI 359 >gi|126443857|ref|YP_001062487.1| calcium/proton exchanger [Burkholderia pseudomallei 668] gi|126455634|ref|YP_001075439.1| calcium/cation antiporter [Burkholderia pseudomallei 1106a] gi|134283484|ref|ZP_01770184.1| calcium/cation antiporter (CaCA) family [Burkholderia pseudomallei 305] 26 more sequence titles Length=361 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 196/355 (56%), Positives = 247/355 (70%), Gaps = 9/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVL---AAVNHAEVVAARVGEPFGS 63 WT+V P A++ L L+ ++ P G A + A +AV+HAEVVA RVGEPFG+ Sbjct 11 WTLVAPLAAWLVLALS---RVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGT 67 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLA+AVT IEVALIV++M+S G + A LARDTVFAAVMI NGI GL LL+G R+G Sbjct 68 LVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQ 127 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP LS QL FAG +SL LY +F+F QT Sbjct 128 DFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQT 187 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL G+ ++ HA PPS R AL S+ L V+LVAVV LAK+ SP +E V Sbjct 188 VRHRDYFL---IDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVL 244 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 245 RLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVF 304 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 305 IWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSI 359 >gi|167819605|ref|ZP_02451285.1| calcium/proton exchanger [Burkholderia pseudomallei 91] Length=396 Score = 313 bits (803), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 196/355 (56%), Positives = 247/355 (70%), Gaps = 9/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVL---AAVNHAEVVAARVGEPFGS 63 WT+V P A++ L L+ ++ P G A + A +AV+HAEVVA RVGEPFG+ Sbjct 46 WTLVAPLAAWLVLALS---RVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGT 102 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLA+AVT IEVALIV++M+S G + A LARDTVFAAVMI NGI GL LL+G R+G Sbjct 103 LVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQ 162 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP LS QL FAG +SL LY +F+F QT Sbjct 163 DFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQT 222 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL G+ ++ HA PPS R AL S+ L V+LVAVV LAK+ SP +E V Sbjct 223 VRHRDYFL---IDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVL 279 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 280 RLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVF 339 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 340 IWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSI 394 >gi|167742439|ref|ZP_02415213.1| calcium/proton exchanger [Burkholderia pseudomallei 14] Length=398 Score = 313 bits (803), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 196/355 (56%), Positives = 247/355 (70%), Gaps = 9/355 (2%) Query 7 WTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVL---AAVNHAEVVAARVGEPFGS 63 WT+V P A++ L L+ ++ P G A + A +AV+HAEVVA RVGEPFG+ Sbjct 48 WTLVAPLAAWLVLALS---RVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGT 104 Query 64 LVLAVAVTTIEVALIVALMVSGGDDAATLARDTVFAAVMITTNGIAGLSLLLGSLRYGVT 123 LVLA+AVT IEVALIV++M+S G + A LARDTVFAAVMI NGI GL LL+G R+G Sbjct 105 LVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQ 164 Query 124 LFNPHGSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQT 183 F G+ ALA + +L+ LSLV+P + ++ GP LS QL FAG +SL LY +F+F QT Sbjct 165 DFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQT 224 Query 184 VRHRDFFLPVAQKGAVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEVVS 243 VRHRD+FL G+ ++ HA PPS R AL S+ L V+LVAVV LAK+ SP +E V Sbjct 225 VRHRDYFL---IDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVL 281 Query 244 AAGFPQSFVGVVIATLVLLPETLAAARAARQGRLQTSLNLAYGSAMASIGLTIPTIALAS 303 G P++ VG+VIA LVLLPE LAA AAR RLQTS+NLA GSA+ASIGLTIPT+A Sbjct 282 RLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVF 341 Query 304 LWLSGPLQLGLGAIQLVLLVLTVVVSVLTVVPGRATRLQGEVHLVLLAAYLFLAV 358 +W PL LG+GA++ VLL LT++VS LT+ GR T L G VHL L AAYLFL++ Sbjct 342 IWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSI 396 Lambda K H 0.323 0.137 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 672876525450 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40