BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1647 Length=316 Score E Sequences producing significant alignments: (Bits) Value gi|15608785|ref|NP_216163.1| hypothetical protein Rv1647 [Mycoba... 629 2e-178 gi|15841103|ref|NP_336140.1| hypothetical protein MT1685 [Mycoba... 627 8e-178 gi|31792834|ref|NP_855327.1| hypothetical protein Mb1674 [Mycoba... 625 2e-177 gi|306797464|ref|ZP_07435766.1| hypothetical protein TMFG_00730 ... 625 3e-177 gi|289447257|ref|ZP_06437001.1| conserved hypothetical protein [... 624 8e-177 gi|340626653|ref|YP_004745105.1| hypothetical protein MCAN_16561... 622 2e-176 gi|289443101|ref|ZP_06432845.1| conserved hypothetical protein [... 610 1e-172 gi|308372019|ref|ZP_07427069.2| hypothetical protein TMDG_02279 ... 601 5e-170 gi|339294602|gb|AEJ46713.1| hypothetical protein CCDC5079_1523 [... 565 5e-159 gi|183982468|ref|YP_001850759.1| hypothetical protein MMAR_2454 ... 482 4e-134 gi|118617272|ref|YP_905604.1| hypothetical protein MUL_1633 [Myc... 461 5e-128 gi|15827733|ref|NP_301996.1| hypothetical protein ML1399 [Mycoba... 437 1e-120 gi|240168032|ref|ZP_04746691.1| hypothetical protein MkanA1_0186... 428 6e-118 gi|118462244|ref|YP_882306.1| adenylate and guanylate cyclase ca... 426 2e-117 gi|342860768|ref|ZP_08717418.1| adenylate and guanylate cyclase ... 425 5e-117 gi|296164545|ref|ZP_06847116.1| adenylate and guanylate cyclase ... 424 1e-116 gi|254821226|ref|ZP_05226227.1| adenylate and guanylate cyclase ... 421 1e-115 gi|41407455|ref|NP_960291.1| hypothetical protein MAP1357 [Mycob... 367 1e-99 gi|120404295|ref|YP_954124.1| putative adenylate/guanylate cycla... 354 8e-96 gi|108799941|ref|YP_640138.1| adenylate/guanylate cyclase [Mycob... 354 9e-96 gi|126435569|ref|YP_001071260.1| putative adenylate/guanylate cy... 351 1e-94 gi|118467453|ref|YP_888073.1| adenylate and guanylate cyclase ca... 349 4e-94 gi|54145497|gb|AAV30110.1| Cya1647 [Mycobacterium smegmatis str.... 340 2e-91 gi|333990465|ref|YP_004523079.1| hypothetical protein JDM601_182... 338 5e-91 gi|315444455|ref|YP_004077334.1| family 3 adenylate cyclase [Myc... 334 1e-89 gi|145224119|ref|YP_001134797.1| putative adenylate/guanylate cy... 334 1e-89 gi|169629416|ref|YP_001703065.1| putative purine cyclase-like pr... 333 3e-89 gi|226361313|ref|YP_002779091.1| adenylate cyclase [Rhodococcus ... 288 7e-76 gi|111019177|ref|YP_702149.1| adenylate cyclase [Rhodococcus jos... 286 4e-75 gi|226304975|ref|YP_002764933.1| adenylate cyclase [Rhodococcus ... 281 1e-73 gi|229493721|ref|ZP_04387505.1| adenylate and Guanylate cyclase ... 278 7e-73 gi|54027308|ref|YP_121550.1| hypothetical protein nfa53340 [Noca... 255 7e-66 gi|312141224|ref|YP_004008560.1| adenylate/guanylate cyclase [Rh... 237 2e-60 gi|325673946|ref|ZP_08153636.1| adenylate cyclase [Rhodococcus e... 237 2e-60 gi|319950304|ref|ZP_08024223.1| adenylate cyclase [Dietzia cinna... 216 5e-54 gi|333918220|ref|YP_004491801.1| putative adenylate cyclase [Amy... 211 2e-52 gi|134100519|ref|YP_001106180.1| adenylate cyclase [Saccharopoly... 169 5e-40 gi|326382309|ref|ZP_08204001.1| adenylyl cyclase class-3/4/guany... 144 1e-32 gi|262202416|ref|YP_003273624.1| adenylyl cyclase class-3/4/guan... 139 7e-31 gi|296140428|ref|YP_003647671.1| adenylate/guanylate cyclase [Ts... 127 3e-27 gi|220920130|ref|YP_002495431.1| adenylate/guanylate cyclase [Me... 75.1 1e-11 gi|333922094|ref|YP_004495675.1| adenylate and guanylate cyclase... 74.7 2e-11 gi|240173219|ref|ZP_04751877.1| hydrolase [Mycobacterium kansasi... 73.9 3e-11 gi|85858076|ref|YP_460278.1| HD domain-containing protein [Syntr... 73.2 5e-11 gi|218674331|ref|ZP_03524000.1| adenylate/guanylate cyclase [Rhi... 73.2 6e-11 gi|339504305|ref|YP_004691725.1| adenylate cyclase [Roseobacter ... 72.4 9e-11 gi|222082394|ref|YP_002541759.1| adenylate/guanylate cyclase pro... 72.0 1e-10 gi|218662623|ref|ZP_03518553.1| adenylate/guanylate cyclase prot... 71.2 2e-10 gi|257059165|ref|YP_003137053.1| adenylate/guanylate cyclase wit... 71.2 2e-10 gi|332527901|ref|ZP_08403938.1| adenylate cyclase [Rubrivivax be... 70.5 3e-10 >gi|15608785|ref|NP_216163.1| hypothetical protein Rv1647 [Mycobacterium tuberculosis H37Rv] gi|148661443|ref|YP_001282966.1| hypothetical protein MRA_1658 [Mycobacterium tuberculosis H37Ra] gi|167968399|ref|ZP_02550676.1| hypothetical protein MtubH3_10331 [Mycobacterium tuberculosis H37Ra] gi|307084228|ref|ZP_07493341.1| hypothetical protein TMLG_00626 [Mycobacterium tuberculosis SUMu012] gi|1838999|emb|CAB06641.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv] gi|148505595|gb|ABQ73404.1| conserved hypothetical protein [Mycobacterium tuberculosis H37Ra] gi|308366149|gb|EFP55000.1| hypothetical protein TMLG_00626 [Mycobacterium tuberculosis SUMu012] Length=316 Score = 629 bits (1621), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 315/316 (99%), Positives = 316/316 (100%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 +AGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH Sbjct 1 MAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS Sbjct 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 Query 301 ESTAADNFDEMSPDAQ 316 ESTAADNFDEMSPDAQ Sbjct 301 ESTAADNFDEMSPDAQ 316 >gi|15841103|ref|NP_336140.1| hypothetical protein MT1685 [Mycobacterium tuberculosis CDC1551] gi|254231847|ref|ZP_04925174.1| conserved hypothetical protein [Mycobacterium tuberculosis C] gi|13881318|gb|AAK45954.1| purine cyclase-related protein [Mycobacterium tuberculosis CDC1551] gi|124600906|gb|EAY59916.1| conserved hypothetical protein [Mycobacterium tuberculosis C] Length=327 Score = 627 bits (1617), Expect = 8e-178, Method: Compositional matrix adjust. Identities = 315/316 (99%), Positives = 315/316 (99%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 L GSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH Sbjct 12 LPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 71 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 72 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 131 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 132 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 191 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 192 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 251 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS Sbjct 252 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 311 Query 301 ESTAADNFDEMSPDAQ 316 ESTAADNFDEMSPDAQ Sbjct 312 ESTAADNFDEMSPDAQ 327 >gi|31792834|ref|NP_855327.1| hypothetical protein Mb1674 [Mycobacterium bovis AF2122/97] gi|121637555|ref|YP_977778.1| hypothetical protein BCG_1686 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148822855|ref|YP_001287609.1| hypothetical protein TBFG_11664 [Mycobacterium tuberculosis F11] 57 more sequence titles Length=316 Score = 625 bits (1613), Expect = 2e-177, Method: Compositional matrix adjust. Identities = 314/316 (99%), Positives = 315/316 (99%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 + GSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH Sbjct 1 MPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS Sbjct 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 Query 301 ESTAADNFDEMSPDAQ 316 ESTAADNFDEMSPDAQ Sbjct 301 ESTAADNFDEMSPDAQ 316 >gi|306797464|ref|ZP_07435766.1| hypothetical protein TMFG_00730 [Mycobacterium tuberculosis SUMu006] gi|308342207|gb|EFP31058.1| hypothetical protein TMFG_00730 [Mycobacterium tuberculosis SUMu006] Length=316 Score = 625 bits (1612), Expect = 3e-177, Method: Compositional matrix adjust. Identities = 313/316 (99%), Positives = 315/316 (99%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 + GSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH Sbjct 1 MPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLA+YRIKTVS Sbjct 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAVYRIKTVS 300 Query 301 ESTAADNFDEMSPDAQ 316 ESTAADNFDEMSPDAQ Sbjct 301 ESTAADNFDEMSPDAQ 316 >gi|289447257|ref|ZP_06437001.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A] gi|289420215|gb|EFD17416.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A] Length=316 Score = 624 bits (1608), Expect = 8e-177, Method: Compositional matrix adjust. Identities = 313/316 (99%), Positives = 314/316 (99%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 + GSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH Sbjct 1 MPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS Sbjct 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 Query 301 ESTAADNFDEMSPDAQ 316 EST ADNFDEMSPDAQ Sbjct 301 ESTVADNFDEMSPDAQ 316 >gi|340626653|ref|YP_004745105.1| hypothetical protein MCAN_16561 [Mycobacterium canettii CIPT 140010059] gi|340004843|emb|CCC43988.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=316 Score = 622 bits (1605), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 313/316 (99%), Positives = 314/316 (99%), Gaps = 0/316 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 + GSARTTYPCHVEVGPQDSESGAPDETATAMASPV RQRSALRWLRTVNRSPGLVSFIH Sbjct 1 MPGSARTTYPCHVEVGPQDSESGAPDETATAMASPVHRQRSALRWLRTVNRSPGLVSFIH 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG Sbjct 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS Sbjct 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 Query 301 ESTAADNFDEMSPDAQ 316 ESTAADNFDEMSPDAQ Sbjct 301 ESTAADNFDEMSPDAQ 316 >gi|289443101|ref|ZP_06432845.1| conserved hypothetical protein [Mycobacterium tuberculosis T46] gi|289416020|gb|EFD13260.1| conserved hypothetical protein [Mycobacterium tuberculosis T46] Length=326 Score = 610 bits (1573), Expect = 1e-172, Method: Compositional matrix adjust. Identities = 307/307 (100%), Positives = 307/307 (100%), Gaps = 0/307 (0%) Query 10 PCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGD 69 PCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGD Sbjct 20 PCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGD 79 Query 70 PEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEV 129 PEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEV Sbjct 80 PEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEV 139 Query 130 TLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPT 189 TLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPT Sbjct 140 TLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPT 199 Query 190 VALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGG 249 VALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGG Sbjct 200 VALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGG 259 Query 250 IMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFD 309 IMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFD Sbjct 260 IMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFD 319 Query 310 EMSPDAQ 316 EMSPDAQ Sbjct 320 EMSPDAQ 326 >gi|308372019|ref|ZP_07427069.2| hypothetical protein TMDG_02279 [Mycobacterium tuberculosis SUMu004] gi|308334696|gb|EFP23547.1| hypothetical protein TMDG_02279 [Mycobacterium tuberculosis SUMu004] Length=304 Score = 601 bits (1549), Expect = 5e-170, Method: Compositional matrix adjust. Identities = 303/304 (99%), Positives = 304/304 (100%), Gaps = 0/304 (0%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF 72 +EVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF Sbjct 1 MEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF 60 Query 73 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV 132 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV Sbjct 61 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV 120 Query 133 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL 192 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL Sbjct 121 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL 180 Query 193 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI 252 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI Sbjct 181 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI 240 Query 253 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMS 312 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMS Sbjct 241 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMS 300 Query 313 PDAQ 316 PDAQ Sbjct 301 PDAQ 304 >gi|339294602|gb|AEJ46713.1| hypothetical protein CCDC5079_1523 [Mycobacterium tuberculosis CCDC5079] gi|339298238|gb|AEJ50348.1| hypothetical protein CCDC5180_1511 [Mycobacterium tuberculosis CCDC5180] Length=285 Score = 565 bits (1455), Expect = 5e-159, Method: Compositional matrix adjust. Identities = 285/285 (100%), Positives = 285/285 (100%), Gaps = 0/285 (0%) Query 32 MASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAA 91 MASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAA Sbjct 1 MASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAA 60 Query 92 DRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDAT 151 DRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDAT Sbjct 61 DRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDAT 120 Query 152 LTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYT 211 LTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYT Sbjct 121 LTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYT 180 Query 212 PRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVV 271 PRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVV Sbjct 181 PRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVV 240 Query 272 ARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMSPDAQ 316 ARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMSPDAQ Sbjct 241 ARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMSPDAQ 285 >gi|183982468|ref|YP_001850759.1| hypothetical protein MMAR_2454 [Mycobacterium marinum M] gi|183175794|gb|ACC40904.1| conserved hypothetical protein [Mycobacterium marinum M] Length=315 Score = 482 bits (1240), Expect = 4e-134, Method: Compositional matrix adjust. Identities = 247/310 (80%), Positives = 273/310 (89%), Gaps = 1/310 (0%) Query 1 LAGSARTTYPCHVEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIH 60 + GSA TTYPC VEVG + + G PDETA +A+ PR+RS + WLR+ N SPG+V+F+ Sbjct 1 MPGSATTTYPCEVEVGADNGDPGVPDETAITLAATAPRRRSPVEWLRSTNHSPGVVAFVR 60 Query 61 RARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAV 120 RARRLLPGDPEFGDPLSTAG+GGPRAAARAADRLL DRDAASREV LSVLQVWQA TEAV Sbjct 61 RARRLLPGDPEFGDPLSTAGDGGPRAAARAADRLLGDRDAASREVSLSVLQVWQAFTEAV 120 Query 121 SRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDG 180 SRRPAN EVTLVFTDLVGFSTWSL AGDDA L LLRQVARAVE PLLDAGGHIVKRLGDG Sbjct 121 SRRPANAEVTLVFTDLVGFSTWSLQAGDDAALKLLRQVARAVEPPLLDAGGHIVKRLGDG 180 Query 181 IMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAAR 240 IMAVFRNPTVA+RAVL+AQDAVK++EV+GYTPRMR+GIHTGRPQRLAADWLGVDVNIAAR Sbjct 181 IMAVFRNPTVAVRAVLIAQDAVKAVEVEGYTPRMRVGIHTGRPQRLAADWLGVDVNIAAR 240 Query 241 VMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVS 300 VMERATKGG+MIS PTLDLIPQSELDA+ VVA+R R+P+FASK TGIPPDLAIYR+ T Sbjct 241 VMERATKGGVMISSPTLDLIPQSELDAMRVVAKRARRPMFASKLTGIPPDLAIYRLTTRK 300 Query 301 E-STAADNFD 309 + +T D D Sbjct 301 DLATIGDTAD 310 >gi|118617272|ref|YP_905604.1| hypothetical protein MUL_1633 [Mycobacterium ulcerans Agy99] gi|118569382|gb|ABL04133.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99] Length=303 Score = 461 bits (1187), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 238/298 (80%), Positives = 264/298 (89%), Gaps = 1/298 (0%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF 72 +EVG + + G PDETA +A+ PR+RS + WLR+ N SPG+V+F+ RARRLLPGDPEF Sbjct 1 MEVGADNGDPGVPDETAITLAATAPRRRSPVEWLRSTNHSPGVVAFVRRARRLLPGDPEF 60 Query 73 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV 132 GDPLSTAG+GGPRAAARAADRLL DRDAASREV LSVLQVWQA TEAVSRRPAN EVTLV Sbjct 61 GDPLSTAGDGGPRAAARAADRLLGDRDAASREVSLSVLQVWQAFTEAVSRRPANAEVTLV 120 Query 133 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL 192 FTDLVGFSTWSL AGDDA L LLRQVARAVE PLLDAGGHIVKRLGDGIMAVFRNPTVA+ Sbjct 121 FTDLVGFSTWSLQAGDDAALKLLRQVARAVEPPLLDAGGHIVKRLGDGIMAVFRNPTVAV 180 Query 193 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI 252 RAVL+AQDAVK++EV+GYTPRMR+GIHTGRPQRLAADWLGVDVNIAARVMERATKGG+MI Sbjct 181 RAVLIAQDAVKAVEVEGYTPRMRVGIHTGRPQRLAADWLGVDVNIAARVMERATKGGVMI 240 Query 253 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSE-STAADNFD 309 S PTLDLIPQSELDA+ VVA+R R+P+FASK TGIPPDLAIYR+ T + +T D D Sbjct 241 SSPTLDLIPQSELDAMRVVAKRARRPMFASKLTGIPPDLAIYRLTTRKDLATIGDTAD 298 >gi|15827733|ref|NP_301996.1| hypothetical protein ML1399 [Mycobacterium leprae TN] gi|221230210|ref|YP_002503626.1| hypothetical protein MLBr_01399 [Mycobacterium leprae Br4923] gi|13093284|emb|CAC31780.1| conserved hypothetical protein [Mycobacterium leprae] gi|219933317|emb|CAR71494.1| conserved hypothetical protein [Mycobacterium leprae Br4923] Length=324 Score = 437 bits (1123), Expect = 1e-120, Method: Compositional matrix adjust. Identities = 230/313 (74%), Positives = 260/313 (84%), Gaps = 9/313 (2%) Query 4 SARTTYPCHVEVGPQDSESGAP---DETATAMASPVPRQRSAL------RWLRTVNRSPG 54 SA++TYP VE P D AP DE + +P +RS++ +WL T NRSP Sbjct 4 SAKSTYPGQVEGAPHDGTPSAPQEPDEDTVTVPAPALIRRSSVSMPNAAQWLHTTNRSPR 63 Query 55 LVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQ 114 LV+ + RARRLLPGDP+FGDPLSTAGEGGPRAAARAADRLL DR AASREV LSVLQVWQ Sbjct 64 LVAMVRRARRLLPGDPDFGDPLSTAGEGGPRAAARAADRLLGDRGAASREVSLSVLQVWQ 123 Query 115 ALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIV 174 ALTEA++RRP NPEVTLVFTDLVGFS WSL AGD+ATL LLRQVARAVESPLLDAGGHIV Sbjct 124 ALTEAIARRPVNPEVTLVFTDLVGFSGWSLQAGDEATLALLRQVARAVESPLLDAGGHIV 183 Query 175 KRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVD 234 KR+GDGIMAVFR+P+VA++AVL A +A+KS+EV GYTPR+R+GIHTGRPQRLAADWLGVD Sbjct 184 KRMGDGIMAVFRDPSVAVQAVLAATEAMKSVEVGGYTPRIRVGIHTGRPQRLAADWLGVD 243 Query 235 VNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIY 294 VNIAARVMERATKGGIMIS PTLDLIPQS+L LG++ RRVRKP+F SK TGIPPD+ IY Sbjct 244 VNIAARVMERATKGGIMISGPTLDLIPQSDLKELGIITRRVRKPMFTSKFTGIPPDMVIY 303 Query 295 RIKTVSESTAADN 307 RIK E TA+D Sbjct 304 RIKARRELTASDE 316 >gi|240168032|ref|ZP_04746691.1| hypothetical protein MkanA1_01860 [Mycobacterium kansasii ATCC 12478] Length=292 Score = 428 bits (1100), Expect = 6e-118, Method: Compositional matrix adjust. Identities = 228/277 (83%), Positives = 251/277 (91%), Gaps = 0/277 (0%) Query 25 PDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGP 84 PDETATA+A R+RS +WLR+ N SPG+V+FI RARRLLPGDPEFGDPLSTAG+GGP Sbjct 2 PDETATAVAPSASRRRSPGQWLRSTNHSPGVVAFIRRARRLLPGDPEFGDPLSTAGDGGP 61 Query 85 RAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSL 144 RAAARAADRLL DRDAASREV L VLQ+WQALTEAVSRRP NPEVTLVFTDLVGFSTWSL Sbjct 62 RAAARAADRLLGDRDAASREVSLGVLQLWQALTEAVSRRPVNPEVTLVFTDLVGFSTWSL 121 Query 145 HAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKS 204 AGDDATL LLR+VARAVE PLLDAGGHIVKR+GDGIMAVFRNP VA+RAVL A++A+ + Sbjct 122 QAGDDATLALLRRVARAVEPPLLDAGGHIVKRMGDGIMAVFRNPAVAVRAVLAAREALSA 181 Query 205 LEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSE 264 +EV GYTPRMR+GIHTGRPQRLAADWLG+DVNIAARVMERATKGGIMIS PTLDLIPQSE Sbjct 182 VEVAGYTPRMRVGIHTGRPQRLAADWLGIDVNIAARVMERATKGGIMISSPTLDLIPQSE 241 Query 265 LDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSE 301 LDALGVVA+R R+P+F+SK TGIPPDLAIYR+K E Sbjct 242 LDALGVVAKRARRPMFSSKLTGIPPDLAIYRLKPRKE 278 >gi|118462244|ref|YP_882306.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium avium 104] gi|254775572|ref|ZP_05217088.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118163531|gb|ABK64428.1| adenylate and Guanylate cyclase catalytic domain protein [Mycobacterium avium 104] gi|336457809|gb|EGO36803.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis S397] Length=306 Score = 426 bits (1095), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 222/307 (73%), Positives = 257/307 (84%), Gaps = 9/307 (2%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQRSAL------RWLRTVNRSPGLVSFIHRARRLL 66 +E+ +D + G P+E+A A ++ +R+AL +WL N SPG V+ + RARRLL Sbjct 1 MELARRDLDPGEPEESAAAQSA---SRRTALSVHNATQWLHNRNHSPGAVALVRRARRLL 57 Query 67 PGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPAN 126 PGDP+FGDPLSTAG+GGPRAAARAADRLL DRDA SREV L VLQVWQALTE +SRRPAN Sbjct 58 PGDPDFGDPLSTAGDGGPRAAARAADRLLGDRDAVSREVSLGVLQVWQALTEGISRRPAN 117 Query 127 PEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFR 186 PEVTLVFTDLVGFSTWSL AGDDA L LLRQVARAVE PLLDAGGHIVKR+GDG+MAVF Sbjct 118 PEVTLVFTDLVGFSTWSLQAGDDAALALLRQVARAVEPPLLDAGGHIVKRMGDGLMAVFG 177 Query 187 NPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERAT 246 +PTVA+RAVL A++A++S+EV GYTPRMR+GIHTGRPQRLA+DWLGVDVNIAARVMERAT Sbjct 178 DPTVAVRAVLAAKEALRSVEVAGYTPRMRVGIHTGRPQRLASDWLGVDVNIAARVMERAT 237 Query 247 KGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAAD 306 KGGIM+S TLD IPQSELDALGV A+R RKPVF KP G+P DLAIYR+KT+ E +A+D Sbjct 238 KGGIMVSSSTLDHIPQSELDALGVEAKRTRKPVFGPKPAGMPADLAIYRLKTLKELSASD 297 Query 307 NFDEMSP 313 + DE P Sbjct 298 DTDETKP 304 >gi|342860768|ref|ZP_08717418.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium colombiense CECT 3035] gi|342131792|gb|EGT85049.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium colombiense CECT 3035] Length=303 Score = 425 bits (1092), Expect = 5e-117, Method: Compositional matrix adjust. Identities = 220/301 (74%), Positives = 250/301 (84%), Gaps = 0/301 (0%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF 72 +E+ +D + G P+ET + SA +WL + NRSPG V+ I RAR+LLPGDPEF Sbjct 1 MELARRDLDPGKPEETEAQSVTQRSPLHSATQWLHSRNRSPGAVALIRRARKLLPGDPEF 60 Query 73 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV 132 GDPLSTAG+GGPRAAARAADRLL DRDA SREV L VLQVWQALTE VSRRPAN EVTLV Sbjct 61 GDPLSTAGDGGPRAAARAADRLLGDRDAVSREVSLGVLQVWQALTEGVSRRPANAEVTLV 120 Query 133 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL 192 FTDLVGFSTWSL AGDDA L LLRQVARA+E PLLDAGGHIVKR+GDG+MAVF +PTVA+ Sbjct 121 FTDLVGFSTWSLQAGDDAALALLRQVARAIEPPLLDAGGHIVKRMGDGLMAVFGDPTVAV 180 Query 193 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI 252 RAVL A++++KS+EV G+TPRMR+GIHTGRPQRLAADWLGVDVNIAARVMER TKGGIM+ Sbjct 181 RAVLAAKESLKSVEVAGHTPRMRVGIHTGRPQRLAADWLGVDVNIAARVMERGTKGGIMV 240 Query 253 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMS 312 S TLDLIPQSELDALGV A+R RKPVF KP GIP DLAIYR+KT+ E + +D+ E Sbjct 241 SSSTLDLIPQSELDALGVEAKRTRKPVFGPKPAGIPDDLAIYRLKTLKELSGSDDTAETK 300 Query 313 P 313 P Sbjct 301 P 301 >gi|296164545|ref|ZP_06847116.1| adenylate and guanylate cyclase catalytic domain protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900145|gb|EFG79580.1| adenylate and guanylate cyclase catalytic domain protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=307 Score = 424 bits (1090), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 220/305 (73%), Positives = 258/305 (85%), Gaps = 6/305 (1%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQ-----RSALRWLRTVNRSPGLVSFIHRARRLLP 67 +E+ DS+SG P++ + P PR+ + A +WL + N SPG V+FI RARR+LP Sbjct 1 MELARHDSDSGEPEQPTVTPSDP-PRRSPVSVQGASQWLHSRNHSPGAVAFIRRARRMLP 59 Query 68 GDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANP 127 GDPEFGDPLSTAG+GGPRAAARAADRLL DRDA SREV L +LQVWQALTE+VSRRPANP Sbjct 60 GDPEFGDPLSTAGDGGPRAAARAADRLLGDRDAVSREVSLGLLQVWQALTESVSRRPANP 119 Query 128 EVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRN 187 EVTLVFTDLVGFS+WSL AGD+A L+LLRQVARAVE PLLDAGGHIVKR+GDG+MAVF + Sbjct 120 EVTLVFTDLVGFSSWSLQAGDEAALSLLRQVARAVEPPLLDAGGHIVKRMGDGLMAVFSD 179 Query 188 PTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATK 247 PTVA+R+VLVA++A+KS+EV GYTPRMR+GIHTGRP RLAADWLGVDVN+AARVMERATK Sbjct 180 PTVAVRSVLVAKEALKSVEVAGYTPRMRVGIHTGRPHRLAADWLGVDVNVAARVMERATK 239 Query 248 GGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADN 307 GGIM+S TLDLI QSELDA+GVVA+R RK VFA K TG+P DLAIYR++T E TA+D+ Sbjct 240 GGIMVSSSTLDLIAQSELDAMGVVAKRARKSVFAGKTTGVPADLAIYRLRTQRELTASDH 299 Query 308 FDEMS 312 E + Sbjct 300 SSETN 304 >gi|254821226|ref|ZP_05226227.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium intracellulare ATCC 13950] Length=306 Score = 421 bits (1081), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 222/305 (73%), Positives = 253/305 (83%), Gaps = 5/305 (1%) Query 13 VEVGPQDSESGAPDETATAMA----SPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPG 68 +E+ +D + G PDE+ A + +P+ +A +WL N SPG V+ + RARRLLPG Sbjct 1 MELARRDLKPGEPDESRAAHSASRRTPLSVH-NATQWLHGRNHSPGAVALVRRARRLLPG 59 Query 69 DPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPE 128 DPEFGDPLSTAG+GGPRAAARAADRLL DRDA SREV L VLQVWQALTE VSRRPANPE Sbjct 60 DPEFGDPLSTAGDGGPRAAARAADRLLGDRDAVSREVSLGVLQVWQALTEGVSRRPANPE 119 Query 129 VTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNP 188 VTLVFTDLVGFSTWSL AGDDA L LLRQVARA+E PLLDAGGHIVKR+GDG+MAVF +P Sbjct 120 VTLVFTDLVGFSTWSLRAGDDAALALLRQVARALEPPLLDAGGHIVKRMGDGLMAVFGDP 179 Query 189 TVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKG 248 TVA+RAVL A++AV S+EV+GYTPRMR+GIHTGRPQRLA+DWLGVDVNIAARVMERATKG Sbjct 180 TVAVRAVLAAKEAVGSVEVEGYTPRMRVGIHTGRPQRLASDWLGVDVNIAARVMERATKG 239 Query 249 GIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNF 308 GIM+S TLDLIPQSELDALGV A+R RKPVF KP G+P DLAIYR+KT E + +D+ Sbjct 240 GIMVSSSTLDLIPQSELDALGVEAKRTRKPVFGPKPAGMPADLAIYRLKTFRELSGSDDT 299 Query 309 DEMSP 313 E P Sbjct 300 AETKP 304 >gi|41407455|ref|NP_960291.1| hypothetical protein MAP1357 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395807|gb|AAS03674.1| hypothetical protein MAP_1357 [Mycobacterium avium subsp. paratuberculosis K-10] Length=322 Score = 367 bits (942), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 182/230 (80%), Positives = 202/230 (88%), Gaps = 0/230 (0%) Query 84 PRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWS 143 P AARAADRLL DRDA SREV L VLQVWQALTE +SRRPANPEVTLVFTDLVGFSTWS Sbjct 91 PAMAARAADRLLGDRDAVSREVSLGVLQVWQALTEGISRRPANPEVTLVFTDLVGFSTWS 150 Query 144 LHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVK 203 L AGDDA L LLRQVARAVE PLLDAGGHIVKR+GDG+MAVF +PTVA+RAVL A++A++ Sbjct 151 LQAGDDAALALLRQVARAVEPPLLDAGGHIVKRMGDGLMAVFGDPTVAVRAVLAAKEALR 210 Query 204 SLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQS 263 S+EV GYTPRMR+GIHTGRPQRLA+DWLGVDVNIAARVMERATKGGIM+S TLD IPQS Sbjct 211 SVEVAGYTPRMRVGIHTGRPQRLASDWLGVDVNIAARVMERATKGGIMVSSSTLDHIPQS 270 Query 264 ELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMSP 313 ELDALGV A+R RKPVF KP G+P DLAIYR+KT+ E +A+D+ DE P Sbjct 271 ELDALGVEAKRTRKPVFGPKPAGMPADLAIYRLKTLKELSASDDTDETKP 320 >gi|120404295|ref|YP_954124.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] gi|119957113|gb|ABM14118.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] Length=270 Score = 354 bits (909), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 175/263 (67%), Positives = 213/263 (81%), Gaps = 1/263 (0%) Query 45 WLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASRE 104 WL VN G+V+F+ RARR LPGDP+FGDPLS +G GGP AAARAADR L +R+A +RE Sbjct 3 WLMGVNHHDGVVAFLRRARRALPGDPDFGDPLSVSGVGGPSAAARAADRYL-ERNAVTRE 61 Query 105 VGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVES 164 V L LQVWQALTE VS RPAN EVTLVFTDLVGFSTWSL AGDDATL LLR+VA+ VE Sbjct 62 VSLGALQVWQALTERVSGRPANAEVTLVFTDLVGFSTWSLGAGDDATLRLLRRVAQVVEP 121 Query 165 PLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQ 224 PLL+AGGHIVKR+GDG+MAVF + T A+RA + A+DAVKSL+V GYTPRMR+GIHTGRPQ Sbjct 122 PLLEAGGHIVKRMGDGLMAVFTDATTAVRAAIEARDAVKSLDVDGYTPRMRVGIHTGRPQ 181 Query 225 RLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKP 284 R+ +DWLG+DVN+AARVMERAT+G +++S TL+ IP E LGV A+++R+PVFA K Sbjct 182 RIGSDWLGIDVNLAARVMERATRGELVVSGATLERIPDDEFQTLGVTAKKLRRPVFAGKQ 241 Query 285 TGIPPDLAIYRIKTVSESTAADN 307 G+P D A+YR++T +S A+ Sbjct 242 DGVPGDFAMYRLRTHRQSPGAEE 264 >gi|108799941|ref|YP_640138.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119869051|ref|YP_939003.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] gi|108770360|gb|ABG09082.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119695140|gb|ABL92213.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] Length=333 Score = 354 bits (909), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 183/300 (61%), Positives = 226/300 (76%), Gaps = 5/300 (1%) Query 13 VEVGPQDSESGAPDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEF 72 VEV P D SG ++ A PV L W + N SP +V F+ RARR LPGDP+F Sbjct 39 VEVKPFDERSGGTEDEERA---PVRGSAGPLGWFYSANHSPSVVEFLRRARRALPGDPDF 95 Query 73 GDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLV 132 GDPLS G GGPRAAAR ADRLL DR+A SREV L LQ+WQA+TE VS +PANPEVTLV Sbjct 96 GDPLSADGVGGPRAAARVADRLL-DREAVSREVSLGALQLWQAVTERVSGKPANPEVTLV 154 Query 133 FTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVAL 192 F+DLVGFS+W+L AGDDATL LLR+VA+A E PLL+AGG IVKR+GDG MAVF +P A+ Sbjct 155 FSDLVGFSSWALTAGDDATLRLLRRVAQAYEPPLLEAGGRIVKRMGDGSMAVFTDPGTAV 214 Query 193 RAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMI 252 RAVL A AV+S+E+ GY+PRMR+G+HTGRPQR+ +DWLGVDVN AARVMERAT+GG+++ Sbjct 215 RAVLNAMAAVRSVEIDGYSPRMRVGVHTGRPQRIGSDWLGVDVNTAARVMERATRGGLIV 274 Query 253 SQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAADNFDEMS 312 SQ TLD IP EL AL V +R R+ VF+ KP G+PP+L +YR++ + + D+ D+ S Sbjct 275 SQATLDRIPAEELAALNVTVKRQRRQVFSLKPDGVPPELGMYRVRR-NRPSGEDSTDDDS 333 >gi|126435569|ref|YP_001071260.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] gi|126235369|gb|ABN98769.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] Length=275 Score = 351 bits (900), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 172/255 (68%), Positives = 209/255 (82%), Gaps = 1/255 (0%) Query 43 LRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAAS 102 L W + N SP +V F+ RARR LPGDP+FGDPLS G GGPRAAAR ADRLL DR+A S Sbjct 8 LGWFYSANHSPSVVEFLRRARRALPGDPDFGDPLSADGVGGPRAAARVADRLL-DREAVS 66 Query 103 REVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAV 162 REV L LQ+WQA+TE VS +PANPEVTLVF+DLVGFS+W+L AGDDATL LLR+VA+A Sbjct 67 REVSLGALQLWQAVTERVSGKPANPEVTLVFSDLVGFSSWALTAGDDATLRLLRRVAQAY 126 Query 163 ESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGR 222 E PLL+AGG IVKR+GDG MAVF +P A+RAVL A AV+S+E+ GY+PRMR+G+HTGR Sbjct 127 EPPLLEAGGRIVKRMGDGSMAVFTDPGTAVRAVLNAMAAVRSVEIDGYSPRMRVGVHTGR 186 Query 223 PQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFAS 282 PQR+ +DWLGVDVNIAARVMERAT+GG+++SQ TLD IP EL AL V +R R+ VF+ Sbjct 187 PQRIGSDWLGVDVNIAARVMERATRGGLIVSQATLDRIPAEELAALNVTVKRQRRQVFSL 246 Query 283 KPTGIPPDLAIYRIK 297 KP G+PP+LA+YR++ Sbjct 247 KPDGVPPELAMYRVR 261 >gi|118467453|ref|YP_888073.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium smegmatis str. MC2 155] gi|118168740|gb|ABK69636.1| adenylate and Guanylate cyclase catalytic domain protein [Mycobacterium smegmatis str. MC2 155] Length=260 Score = 349 bits (895), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 178/261 (69%), Positives = 209/261 (81%), Gaps = 1/261 (0%) Query 55 LVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQ 114 +V+ + R RR LPGDPEFGDPLS AG+GGPRAAAR ADRLL +RDAASREV L LQVWQ Sbjct 1 MVAAVRRFRRALPGDPEFGDPLSVAGDGGPRAAARVADRLL-ERDAASREVSLGALQVWQ 59 Query 115 ALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIV 174 ALTE VS RPAN EVTLVFTDLVGFS+WSL AGDDATL LLR+VA+ E PLL+AGGHIV Sbjct 60 ALTERVSGRPANREVTLVFTDLVGFSSWSLRAGDDATLRLLRRVAQVAEPPLLEAGGHIV 119 Query 175 KRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVD 234 KR+GDG+MAVF +P A+RAVLVA DAVK +EV GYTPRMR+GIHTGRPQR+ +DWLGVD Sbjct 120 KRMGDGMMAVFGDPATAVRAVLVALDAVKGIEVDGYTPRMRVGIHTGRPQRIGSDWLGVD 179 Query 235 VNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIY 294 VNI ARVMERA KGG+M+S TL I EL LGV +R R+ +F+++P G+P DL +Y Sbjct 180 VNITARVMERAAKGGLMVSHATLAGIADGELAELGVTVKRERRQLFSARPDGVPEDLVMY 239 Query 295 RIKTVSESTAADNFDEMSPDA 315 R++T S AA ++ PDA Sbjct 240 RVRTPSRLPAARPREQEPPDA 260 >gi|54145497|gb|AAV30110.1| Cya1647 [Mycobacterium smegmatis str. MC2 155] Length=249 Score = 340 bits (872), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 173/250 (70%), Positives = 202/250 (81%), Gaps = 1/250 (0%) Query 66 LPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPA 125 +PGDPEFGDPLS AG+GGPRAAAR ADRLL +RDAASREV L LQVWQALTE VS RPA Sbjct 1 MPGDPEFGDPLSVAGDGGPRAAARVADRLL-ERDAASREVSLGALQVWQALTERVSGRPA 59 Query 126 NPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVF 185 N EVTLVFTDLVGFS+WSL AGDDATL LLR+VA+ E PLL+AGGHIVKR+GDG+MAVF Sbjct 60 NREVTLVFTDLVGFSSWSLRAGDDATLRLLRRVAQVAEPPLLEAGGHIVKRMGDGMMAVF 119 Query 186 RNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERA 245 +P A+RAVLVA DAVK +EV GYTPRMR+GIHTGRPQR+ +DWLGVDVNI ARVMERA Sbjct 120 GDPATAVRAVLVALDAVKGIEVDGYTPRMRVGIHTGRPQRIGSDWLGVDVNITARVMERA 179 Query 246 TKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSESTAA 305 KGG+M+S TL I EL LGV +R R+ +F+++P G+P DL +YR++T S AA Sbjct 180 AKGGLMVSHATLAGIADGELAELGVTVKRERRQLFSARPDGVPEDLVMYRVRTPSRLPAA 239 Query 306 DNFDEMSPDA 315 ++ PDA Sbjct 240 RPREQEPPDA 249 >gi|333990465|ref|YP_004523079.1| hypothetical protein JDM601_1825 [Mycobacterium sp. JDM601] gi|333486433|gb|AEF35825.1| conserved hypothetical protein [Mycobacterium sp. JDM601] Length=301 Score = 338 bits (868), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 178/271 (66%), Positives = 211/271 (78%), Gaps = 5/271 (1%) Query 34 SPVPRQRS-----ALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAA 88 +P R+RS A WL +V + R RR LPGDPEFGDPLSTAG+GGP+AAA Sbjct 23 APSSRRRSFSLDDAAAWLNRTTNDVRVVDLVRRVRRALPGDPEFGDPLSTAGDGGPQAAA 82 Query 89 RAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGD 148 RAA RL+ DR AASREV L LQ+WQALTE +SR P N E TLVFTDLVGFSTWSL +GD Sbjct 83 RAAGRLMGDRSAASREVSLGALQIWQALTERISRAPTNAEATLVFTDLVGFSTWSLRSGD 142 Query 149 DATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQ 208 DATLTLLR+V++AVE PLLDAGG IVKR+GDGIMAVFR P +A+ AVL AQDA+ ++EV Sbjct 143 DATLTLLRRVSQAVEPPLLDAGGRIVKRMGDGIMAVFREPLIAVGAVLEAQDAIATVEVN 202 Query 209 GYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDAL 268 G+TPRMR GIHTGRPQRLA DWLGVDVNIAARVMERA KGGI++S TL+ I +L+ L Sbjct 203 GFTPRMRAGIHTGRPQRLADDWLGVDVNIAARVMERAVKGGIVVSGATLERIEPGDLEEL 262 Query 269 GVVARRVRKPVFASKPTGIPPDLAIYRIKTV 299 GV A+R R+ V ++K +G+P DL +YR+K V Sbjct 263 GVTAKRARRQVLSAKTSGVPADLMMYRLKAV 293 >gi|315444455|ref|YP_004077334.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] gi|315262758|gb|ADT99499.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] Length=290 Score = 334 bits (856), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 166/254 (66%), Positives = 210/254 (83%), Gaps = 1/254 (0%) Query 45 WLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASRE 104 W R +N G+++F+ R RR LPGDP+FGDPLS +G GGPRAAARAADRLL +RDAA+RE Sbjct 20 WFRDINHHDGVIAFLRRTRRALPGDPDFGDPLSVSGVGGPRAAARAADRLL-ERDAATRE 78 Query 105 VGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVES 164 V L LQVWQALTE VS RPANPEVTLVFTDLVGFS WSL +GDDATL LLR+VA+ VE Sbjct 79 VSLGALQVWQALTERVSGRPANPEVTLVFTDLVGFSAWSLRSGDDATLRLLRRVAQVVEP 138 Query 165 PLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQ 224 PLL +GGHIVKR+GDG+MAVF +PT A+R+ + A++AVK+++V GYTPRMR+GIHTGRPQ Sbjct 139 PLLQSGGHIVKRMGDGLMAVFADPTTAVRSAIAAREAVKTVDVDGYTPRMRVGIHTGRPQ 198 Query 225 RLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKP 284 R+ +DWLG+DVN+AARVMERAT+G ++IS+ TL IP + D L V A+++R+ VFA++ Sbjct 199 RIGSDWLGIDVNLAARVMERATRGELVISEATLQRIPDEDFDVLPVTAKKLRRQVFAARA 258 Query 285 TGIPPDLAIYRIKT 298 G+P D +YR++T Sbjct 259 DGVPDDFTMYRLRT 272 >gi|145224119|ref|YP_001134797.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|145216605|gb|ABP46009.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] Length=301 Score = 334 bits (856), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 166/254 (66%), Positives = 210/254 (83%), Gaps = 1/254 (0%) Query 45 WLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASRE 104 W R +N G+++F+ R RR LPGDP+FGDPLS +G GGPRAAARAADRLL +RDAA+RE Sbjct 31 WFRDINHHDGVIAFLRRTRRALPGDPDFGDPLSVSGVGGPRAAARAADRLL-ERDAATRE 89 Query 105 VGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVES 164 V L LQVWQALTE VS RPANPEVTLVFTDLVGFS WSL +GDDATL LLR+VA+ VE Sbjct 90 VSLGALQVWQALTERVSGRPANPEVTLVFTDLVGFSAWSLRSGDDATLRLLRRVAQVVEP 149 Query 165 PLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQ 224 PLL +GGHIVKR+GDG+MAVF +PT A+R+ + A++AVK+++V GYTPRMR+GIHTGRPQ Sbjct 150 PLLQSGGHIVKRMGDGLMAVFADPTTAVRSAIAAREAVKTVDVDGYTPRMRVGIHTGRPQ 209 Query 225 RLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKP 284 R+ +DWLG+DVN+AARVMERAT+G ++IS+ TL IP + D L V A+++R+ VFA++ Sbjct 210 RIGSDWLGIDVNLAARVMERATRGELVISEATLQRIPDEDFDVLPVTAKKLRRQVFAARA 269 Query 285 TGIPPDLAIYRIKT 298 G+P D +YR++T Sbjct 270 DGVPDDFTMYRLRT 283 >gi|169629416|ref|YP_001703065.1| putative purine cyclase-like protein [Mycobacterium abscessus ATCC 19977] gi|169241383|emb|CAM62411.1| Hypothetical purine cyclase-related protein [Mycobacterium abscessus] Length=336 Score = 333 bits (853), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 160/259 (62%), Positives = 201/259 (78%), Gaps = 0/259 (0%) Query 40 RSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRD 99 R+A W R ++R P +V+ + RARR LPGDP FGDPLST+G GG A ARAADRL+ DRD Sbjct 65 RTAGSWFRKMDRDPAVVAALRRARRSLPGDPYFGDPLSTSGFGGASAVARAADRLVTDRD 124 Query 100 AASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVA 159 A RE G LQ+WQA TE VS++PAN EVTLVFTDLVGFS W+L AGD+ATL LLR+VA Sbjct 125 TAVREFGFGALQIWQAFTEKVSKQPANREVTLVFTDLVGFSGWALEAGDEATLKLLRRVA 184 Query 160 RAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIH 219 E PLL AGG +VKR+GDGIMAVF +P ALRA++ A+DA+K++E+QGYTP MRIGIH Sbjct 185 SVSEPPLLSAGGQVVKRMGDGIMAVFDDPVTALRAIIPARDALKNVEIQGYTPVMRIGIH 244 Query 220 TGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPV 279 G PQR+ +DWLGVDVNIAARVME A KGG+ ISQP L +P + LD +G+ VR+P+ Sbjct 245 AGTPQRIGSDWLGVDVNIAARVMESAAKGGLAISQPALAKVPLAFLDHMGLTPTPVRRPL 304 Query 280 FASKPTGIPPDLAIYRIKT 298 F+S+P G+P ++ +Y ++T Sbjct 305 FSSRPAGVPENMKMYLLET 323 >gi|226361313|ref|YP_002779091.1| adenylate cyclase [Rhodococcus opacus B4] gi|226239798|dbj|BAH50146.1| adenylate cyclase [Rhodococcus opacus B4] Length=260 Score = 288 bits (737), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 147/255 (58%), Positives = 180/255 (71%), Gaps = 0/255 (0%) Query 43 LRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAAS 102 L W+ +VNR P L+ + R RR LPGDP FGDPLSTAG G RA AR ADR L + AS Sbjct 2 LGWVGSVNRQPQLIEGLRRVRRALPGDPAFGDPLSTAGPGSARAIARVADRFLDHQPGAS 61 Query 103 REVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAV 162 RE+ L LQVWQAL E R EVT+VFTDLVGFS+WSL AGD ATL LLR VARAV Sbjct 62 REMSLGALQVWQALLERAGRGRGTQEVTIVFTDLVGFSSWSLPAGDGATLALLRDVARAV 121 Query 163 ESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGR 222 E+P++D GGH+VKRLGDG+MAVF +P A+ AV AQ+A+ +EV GY PRMR+GIHTG Sbjct 122 ETPIVDRGGHVVKRLGDGVMAVFSSPDRAIDAVFAAQEALAGVEVDGYRPRMRVGIHTGV 181 Query 223 PQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFAS 282 P+++ +DWLGVDV IAAR+ME G +M S TL + LD LGV + R+ FA Sbjct 182 PRQIGSDWLGVDVTIAARMMELGGDGNVMASSATLSSLQPGTLDELGVGVKPWRRAFFAP 241 Query 283 KPTGIPPDLAIYRIK 297 P+G+P DL I+R++ Sbjct 242 APSGVPSDLGIWRLR 256 >gi|111019177|ref|YP_702149.1| adenylate cyclase [Rhodococcus jostii RHA1] gi|110818707|gb|ABG93991.1| probable adenylate cyclase [Rhodococcus jostii RHA1] Length=284 Score = 286 bits (731), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 151/279 (55%), Positives = 189/279 (68%), Gaps = 1/279 (0%) Query 20 SESGAPDETATAMASPVP-RQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLST 78 S+ A + +A A+ P R L W+ ++NR P L+ + R RR LPGDP FGDPLST Sbjct 2 SDDPAEENSAELDAAQTPKRGDKVLGWVGSINRQPQLIEGLRRFRRALPGDPAFGDPLST 61 Query 79 AGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVG 138 AG G RA AR ADR L + ASRE+ L LQVWQAL E R EVT+VFTDLVG Sbjct 62 AGPGSARAIARVADRFLDHQPGASREMSLGALQVWQALLERTGRGRGTQEVTIVFTDLVG 121 Query 139 FSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVA 198 FS+WSL AGD ATL LLR VARAVE+P++D GGH+VKRLGDG+MAVF +P A+ AV A Sbjct 122 FSSWSLPAGDSATLALLRDVARAVETPIVDRGGHVVKRLGDGVMAVFPSPDRAIDAVFAA 181 Query 199 QDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLD 258 Q+A+ +EV GY PRMR+GIHTG P+++ +DWLGVDV IAAR+M G +M S TL Sbjct 182 QEALAEVEVDGYRPRMRVGIHTGVPRQIGSDWLGVDVTIAARMMGLGGDGNVMASSATLS 241 Query 259 LIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIK 297 + LD LGV + R+ FA P+G+P DL I+R++ Sbjct 242 SLQPGTLDELGVGVKPWRRAFFAPAPSGVPSDLGIWRLR 280 >gi|226304975|ref|YP_002764933.1| adenylate cyclase [Rhodococcus erythropolis PR4] gi|226184090|dbj|BAH32194.1| probable adenylate cyclase [Rhodococcus erythropolis PR4] Length=283 Score = 281 bits (719), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 140/249 (57%), Positives = 178/249 (72%), Gaps = 0/249 (0%) Query 49 VNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLS 108 +NR L+ + R RR LPGDP FGDPLS AG GG RA AR ADRLL + AA+REV L Sbjct 33 LNRRQQLIDALRRLRRALPGDPGFGDPLSLAGPGGARAVARVADRLLDQKPAATREVSLG 92 Query 109 VLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLD 168 LQVWQA E + R + E+T+VFTDLVGFSTWSL AGD ATLTLLR VA+AVE+P+ D Sbjct 93 ALQVWQAALEKMGRGRGDQELTIVFTDLVGFSTWSLEAGDGATLTLLRAVAQAVETPITD 152 Query 169 AGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAA 228 GGH+VKR+GDG+MAVF P AL+AV AQDA+ +++ GYTPRMR+G+HTG P+++ Sbjct 153 NGGHVVKRMGDGLMAVFIRPDAALKAVFTAQDALAEVDLDGYTPRMRVGLHTGTPRQIGD 212 Query 229 DWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIP 288 DWLGVDV IAAR+M G +M+S TL+ + L+ L + R R+ FA+ P G+P Sbjct 213 DWLGVDVTIAARMMGLGGDGNVMMSATTLEELEAGTLEDLDLTIRPWRRGFFATTPNGVP 272 Query 289 PDLAIYRIK 297 DL I+R++ Sbjct 273 VDLGIWRVR 281 >gi|229493721|ref|ZP_04387505.1| adenylate and Guanylate cyclase catalytic domain protein [Rhodococcus erythropolis SK121] gi|229319390|gb|EEN85227.1| adenylate and Guanylate cyclase catalytic domain protein [Rhodococcus erythropolis SK121] Length=283 Score = 278 bits (712), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 139/249 (56%), Positives = 178/249 (72%), Gaps = 0/249 (0%) Query 49 VNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLS 108 +NR L+ + R RR LPGDP FGDPLS AG GG RA AR ADRLL + AA+REV L Sbjct 33 LNRRQQLIDALRRLRRALPGDPGFGDPLSLAGPGGARAVARVADRLLDQKPAATREVSLG 92 Query 109 VLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLD 168 LQVWQA E + R + E+T+VFTDLVGFSTWSL AGD ATLTLLR VA+AVE+P+ D Sbjct 93 ALQVWQAALEKMGRGRGDQELTIVFTDLVGFSTWSLAAGDGATLTLLRAVAQAVETPITD 152 Query 169 AGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAA 228 GGH+VKR+GDG+MAVF P AL+AV AQDA+ +++ GYTPRMR+G+HTG P+++ Sbjct 153 NGGHVVKRMGDGLMAVFIRPDAALKAVFTAQDALAEVDLDGYTPRMRVGLHTGTPRQIGD 212 Query 229 DWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIP 288 DWLGVDV IAAR+M G +++S TL+ + L+ L + R R+ FA+ P G+P Sbjct 213 DWLGVDVTIAARMMGLGGDGNVVMSATTLEELEAGTLEDLDLTIRPWRRGFFATTPNGVP 272 Query 289 PDLAIYRIK 297 DL I+R++ Sbjct 273 VDLGIWRVR 281 >gi|54027308|ref|YP_121550.1| hypothetical protein nfa53340 [Nocardia farcinica IFM 10152] gi|54018816|dbj|BAD60186.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=298 Score = 255 bits (651), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 129/251 (52%), Positives = 170/251 (68%), Gaps = 0/251 (0%) Query 50 NRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSV 109 NR P L+ + RR LPGDP FGDPLS +G GG RA AR A++L+ D A+RE+GL Sbjct 45 NRRPELIDALRSVRRKLPGDPSFGDPLSVSGPGGARAVARVAEKLVGDSPTAARELGLGA 104 Query 110 LQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDA 169 LQVWQA+ E V R + EVT++FTDLV FS+WSL AGD+ TL LLR VA A+E P+ + Sbjct 105 LQVWQAVLERVGRGRGDTEVTVMFTDLVAFSSWSLTAGDEVTLRLLRAVATAIEPPVAEH 164 Query 170 GGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAAD 229 G +VKR+GDG+MAVF A+RA + A+D ++ +E++GY PRMR+G+HTG P+ + D Sbjct 165 RGSVVKRMGDGMMAVFATADDAVRAAVTAKDNLRGVEIEGYQPRMRVGLHTGMPREIGGD 224 Query 230 WLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPP 289 WLGVDVN+AARVM G M+S TL + L ALG + R+ +FA+ G+P Sbjct 225 WLGVDVNVAARVMAAGGNGHTMLSDATLRALHPDTLTALGRTTKPYRRSLFAAPLNGVPD 284 Query 290 DLAIYRIKTVS 300 DL IYR+ VS Sbjct 285 DLRIYRLTRVS 295 >gi|312141224|ref|YP_004008560.1| adenylate/guanylate cyclase [Rhodococcus equi 103S] gi|311890563|emb|CBH49881.1| putative adenylate/guanylate cyclase [Rhodococcus equi 103S] Length=314 Score = 237 bits (605), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 134/257 (53%), Positives = 175/257 (69%), Gaps = 4/257 (1%) Query 41 SALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDA 100 S +W+R +R P LV + R RR LPGDP FGDPLSTAG ARAA R+L Sbjct 56 SVAKWVRDADRQPQLVDAVRRIRRSLPGDPSFGDPLSTAGP----GGARAAARMLDTGAG 111 Query 101 ASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVAR 160 ASREV ++ LQV QA+ E PAN EVT+VFTDLVGFS+WSL GD ATL+LLR+VA Sbjct 112 ASREVSMAALQVLQAVLEKTWGSPANGEVTIVFTDLVGFSSWSLQVGDGATLSLLREVAA 171 Query 161 AVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHT 220 +E P+++ GG +VKRLGDG+M VF +P A+ AV A+ A+ +L+ GY PRMR+G+HT Sbjct 172 TIEPPMIERGGQVVKRLGDGLMVVFDHPDRAVEAVFAARAALATLDHAGYRPRMRVGLHT 231 Query 221 GRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVF 280 G PQ + ADW GVDVN+AAR+ME G +++S T D I + L LG+VARR R+ + Sbjct 232 GAPQPIGADWFGVDVNVAARMMELGGNGNVVVSGNTHDAIGEERLAELGLVARRYRRGLL 291 Query 281 ASKPTGIPPDLAIYRIK 297 A+ G+P DL +Y ++ Sbjct 292 AAPQRGVPEDLRVYVLR 308 >gi|325673946|ref|ZP_08153636.1| adenylate cyclase [Rhodococcus equi ATCC 33707] gi|325555211|gb|EGD24883.1| adenylate cyclase [Rhodococcus equi ATCC 33707] Length=288 Score = 237 bits (605), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 134/257 (53%), Positives = 175/257 (69%), Gaps = 4/257 (1%) Query 41 SALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDA 100 S +W+R +R P LV + R RR LPGDP FGDPLSTAG ARAA R+L Sbjct 30 SVAKWVRDADRQPQLVDAVRRIRRSLPGDPSFGDPLSTAGP----GGARAAARMLDTGAG 85 Query 101 ASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVAR 160 ASREV ++ LQV QA+ E PAN EVT+VFTDLVGFS+WSL GD ATL+LLR+VA Sbjct 86 ASREVSMAALQVLQAVLEKTWGSPANGEVTIVFTDLVGFSSWSLQVGDGATLSLLREVAA 145 Query 161 AVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHT 220 +E P+++ GG +VKRLGDG+M VF +P A+ AV A+ A+ +L+ GY PRMR+G+HT Sbjct 146 TIEPPMIERGGQVVKRLGDGLMVVFDHPDRAVEAVFAARAALATLDHAGYRPRMRVGLHT 205 Query 221 GRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVF 280 G PQ + ADW GVDVN+AAR+ME G +++S T D I + L LG+VARR R+ + Sbjct 206 GAPQPIGADWFGVDVNVAARMMELGGNGNVVVSGNTHDAIGEERLAELGLVARRYRRGLL 265 Query 281 ASKPTGIPPDLAIYRIK 297 A+ G+P DL +Y ++ Sbjct 266 AAPQRGVPEDLRVYVLR 282 >gi|319950304|ref|ZP_08024223.1| adenylate cyclase [Dietzia cinnamea P4] gi|319435996|gb|EFV91197.1| adenylate cyclase [Dietzia cinnamea P4] Length=267 Score = 216 bits (549), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 120/246 (49%), Positives = 156/246 (64%), Gaps = 6/246 (2%) Query 49 VNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLS 108 VN P V ++ RARR LPGD FGDPLS AG G AR A RL DR ASRE+ L Sbjct 23 VNSDPASVEWMRRARRALPGDSGFGDPLSAAGRDGAGTIARLAGRLFDDRTTASREMTLG 82 Query 109 VLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLD 168 LQVWQ L E R EVT+VFTD+VGFS W++ AGD+ L LLR VARA E + Sbjct 83 ALQVWQVLRERTGRAGVGAEVTIVFTDIVGFSDWAMRAGDEDALRLLRDVARATEPEVTR 142 Query 169 AGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAA 228 G +VKRLGDG+MA F +P +AL AV D V +EV G+ PR+R+G+HTGRP+R+ Sbjct 143 HRGVVVKRLGDGLMAAFPSPQLALDAVAACLDGVAGVEVAGWRPRLRVGVHTGRPRRIGG 202 Query 229 DWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIP 288 D+LG+DVNIAAR+ E+A G I++S+ T ++ LD VA R ++ G+P Sbjct 203 DYLGMDVNIAARLAEKAGAGEILVSEVT-----RAGLDP-ARVATRPKRGFRWGGVKGVP 256 Query 289 PDLAIY 294 ++A++ Sbjct 257 EEIAVH 262 >gi|333918220|ref|YP_004491801.1| putative adenylate cyclase [Amycolicicoccus subflavus DQS3-9A1] gi|333480441|gb|AEF39001.1| putative adenylate cyclase [Amycolicicoccus subflavus DQS3-9A1] Length=214 Score = 211 bits (536), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 105/206 (51%), Positives = 144/206 (70%), Gaps = 1/206 (0%) Query 92 DRLLRDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDAT 151 +R+L +REV L LQVWQA+ E R EVT+VFTDLVGFSTW+L AGDDA Sbjct 3 ERVLDPAPGTAREVSLGALQVWQAVLERCGRGRGTSEVTIVFTDLVGFSTWALEAGDDAA 62 Query 152 LTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYT 211 L LLR+VAR VE+ + D G +VKR+GDG+MA+F P++A+ A++ A+ A+K++E GY Sbjct 63 LRLLRKVARCVETEINDHRGQVVKRMGDGLMAIFPAPSLAIEAIVKARRALKAVEESGYK 122 Query 212 PRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVV 271 P+MR+GIHTG P+ + DWLGVDVN+AAR+ME GG++IS TLD + EL+ALG+V Sbjct 123 PKMRVGIHTGSPRAIGDDWLGVDVNVAARIMESGGNGGLVISGQTLDALGDEELEALGLV 182 Query 272 ARRVRKPVFASKPTGIPPDLAIYRIK 297 A+ R+ K G+P + +Y +K Sbjct 183 AKPHRR-FLKVKLAGVPEGVRLYTVK 207 >gi|134100519|ref|YP_001106180.1| adenylate cyclase [Saccharopolyspora erythraea NRRL 2338] gi|291005002|ref|ZP_06562975.1| adenylate cyclase [Saccharopolyspora erythraea NRRL 2338] gi|133913142|emb|CAM03255.1| probable adenylate cyclase [Saccharopolyspora erythraea NRRL 2338] Length=247 Score = 169 bits (428), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 108/252 (43%), Positives = 145/252 (58%), Gaps = 10/252 (3%) Query 47 RTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVG 106 R V+ P L++ R LPGD +GDPLS G R L + + RE+G Sbjct 3 RRVDGDPWLLALAEWLRTRLPGDARYGDPLSIGGSAVSGVLGRRLAVLAARQPSVLRELG 62 Query 107 LSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPL 166 LQVWQ+ E E+ ++FTDL GFSTW+L GDD + +LR+V A+E PL Sbjct 63 FGALQVWQSQAEGEPADEGEQELAVLFTDLAGFSTWTLEVGDDFAVEMLREVGAAIE-PL 121 Query 167 LDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRL 226 + G +VKRLGDG+MAVF + A+ A L A+DAV+ L V+G+ R+R G+H GRP+ L Sbjct 122 VQRRGRLVKRLGDGLMAVFPHAHDAVEAGLAARDAVERLAVRGHRLRLRAGVHVGRPREL 181 Query 227 AADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTG 286 D+ G DVNIAARV A G ++IS TL+ LD G V R RK F +K G Sbjct 182 GQDYFGRDVNIAARVAGAAGAGEVLISSSTLE-----RLDNTGFVLR--RKDFFHAK--G 232 Query 287 IPPDLAIYRIKT 298 +PP + +YR+ T Sbjct 233 VPPGVGVYRVDT 244 >gi|326382309|ref|ZP_08204001.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia neofelifaecis NRRL B-59395] gi|326199039|gb|EGD56221.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia neofelifaecis NRRL B-59395] Length=277 Score = 144 bits (364), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 89/216 (42%), Positives = 126/216 (59%), Gaps = 18/216 (8%) Query 89 RAADRLLR-------DRDAASREVGLSVLQVWQALTEAVSRRPANP-EVTLVFTDLVGFS 140 R +DR+ R DR +A RE+GL+ + VWQ+L E P+ P T++FTDLVGFS Sbjct 68 RTSDRVARLLNDVRPDRPSAIRELGLASVAVWQSLVERRRPDPSGPIPATILFTDLVGFS 127 Query 141 TWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQD 200 +W+L AGDD L LLR+V A + + GG +VK LGDG MAVF A+ A A Sbjct 128 SWALRAGDDQVLELLREVNAACDEVIRAHGGQVVKTLGDGTMAVFLEAGEAITAAHEAVG 187 Query 201 AVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLI 260 AV ++ V + P +R G+HTG P+ + +D+LGVDVNIAARV + A G + +S L Sbjct 188 AVSAIVVGDFRPALRAGLHTGAPRAVGSDFLGVDVNIAARVCDAAGGGEVYVSDSAL--- 244 Query 261 PQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRI 296 Q ++D + RR K G+P +L ++R+ Sbjct 245 AQVDVDDYVIKRRRF-------KAKGVPRELQVFRV 273 >gi|262202416|ref|YP_003273624.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia bronchialis DSM 43247] gi|262085763|gb|ACY21731.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia bronchialis DSM 43247] Length=277 Score = 139 bits (350), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 111/277 (41%), Positives = 151/277 (55%), Gaps = 26/277 (9%) Query 24 APDETATAMASPVPRQRSALRWLRTVNRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGG 83 +P++ A A +P R A +L N S G V ARRLLP P TAG+ Sbjct 17 SPEDRAGADVTPA---RRASEFLARTNASDGAVKAARAARRLLPEAPP-----PTAGD-- 66 Query 84 PRAAARAADRLL----RDRDAASREVGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGF 139 RA+AR A RL+ +R +A RE+GL+ +QVWQ+L R T++FTDLV F Sbjct 67 -RASARLA-RLIGEAGSERPSAVRELGLATVQVWQSLVRRGPRTDRPVPATILFTDLVNF 124 Query 140 STWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQ 199 TW+L GD+ L LL +V + ++ GG IVK LGDG MAVF + T A+ A Sbjct 125 FTWALRVGDEQVLRLLAEVNDVTRTVVVRRGGTIVKHLGDGAMAVFTDGTEAIEAGYETI 184 Query 200 DAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQPTLDL 259 AV +L + GY P++R G+HTG P+ + D+LGVDVNIAARV A G ++ S TLD+ Sbjct 185 CAVSALTIDGYRPQLRAGVHTGTPRAVGDDYLGVDVNIAARVAAAAGPGELLASADTLDV 244 Query 260 IPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRI 296 +E D R + K G+P DL +Y + Sbjct 245 ---AEAD-------RYVRRRRRFKAKGVPADLEVYSV 271 >gi|296140428|ref|YP_003647671.1| adenylate/guanylate cyclase [Tsukamurella paurometabola DSM 20162] gi|296028562|gb|ADG79332.1| adenylate/guanylate cyclase [Tsukamurella paurometabola DSM 20162] Length=275 Score = 127 bits (318), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 93/254 (37%), Positives = 130/254 (52%), Gaps = 23/254 (9%) Query 50 NRSPGLVSFIHRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSV 109 N S + + AR LPG P+ D E R + DR++ D +RE+G Sbjct 36 NHSKTVAGIVRVARENLPGGPK-KDLFHPDAESTERLS-NLIDRIVGDEPTVTRELGNLA 93 Query 110 LQVWQALTEAVSRR-----PANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVES 164 WQAL +SRR P P VT++FTDLV FSTW+LH DD + LL V + + Sbjct 94 TATWQAL---ISRRDRDYLPPRP-VTIMFTDLVSFSTWALHRDDDDIVRLLHAVNKTTKD 149 Query 165 PLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEV-QGYTPRMRIGIHTGRP 223 + GG IVK +GDG +A F T A+ A +AV ++V GY P +R G+HTG P Sbjct 150 LVERHGGVIVKTMGDGALAAFDGDT-AIEAAYEVIEAVGMIDVADGYRPTLRAGLHTGTP 208 Query 224 QRLAADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASK 283 +++ D +GVDVNIAARV E A G ++ S+ + +E D V RR K Sbjct 209 RQVKGDLIGVDVNIAARVAEAANGGEVLASETVFTV---AERDRYQVRPRRF-------K 258 Query 284 PTGIPPDLAIYRIK 297 G P L ++ ++ Sbjct 259 AKGAPQKLQVFSVR 272 >gi|220920130|ref|YP_002495431.1| adenylate/guanylate cyclase [Methylobacterium nodulans ORS 2060] gi|219944736|gb|ACL55128.1| adenylate/guanylate cyclase [Methylobacterium nodulans ORS 2060] Length=471 Score = 75.1 bits (183), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 98/200 (49%), Gaps = 17/200 (8%) Query 64 RLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASREVGLSVLQVWQALTEAVSRR 123 R+LPG G+ L+T G R A RLL ++ A R++ ++ V +R Sbjct 247 RVLPGIFIAGEALNTLI--GGRRPFLTAKRLLSNQ--AFRDI-------YRTDALDVDQR 295 Query 124 PANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMA 183 +T VFTDL G + GD L+R + + + + GG +VK +GD +MA Sbjct 296 LKILSLTFVFTDLTGSTDLYERVGDLVAYDLVRSHFQILTAVVASHGGAVVKTIGDAVMA 355 Query 184 VFRNPTVALRAVLVAQDAVKSLEVQGYTPR--MRIGIHTGRPQRLA----ADWLGVDVNI 237 F P+ A+ A L ++A++ L T ++IG+H G + D+ G VNI Sbjct 356 TFPMPSQAVAAALEMREAMRRLNTGRETDELILKIGLHEGPCLAVLLNDRQDYFGQTVNI 415 Query 238 AARVMERATKGGIMISQPTL 257 AARV E AT G I +S+P + Sbjct 416 AARVQELATSGAIFVSEPVV 435 >gi|333922094|ref|YP_004495675.1| adenylate and guanylate cyclase catalytic domain-containing protein [Amycolicicoccus subflavus DQS3-9A1] gi|333484315|gb|AEF42875.1| adenylate and guanylate cyclase catalytic domain-containing protein [Amycolicicoccus subflavus DQS3-9A1] Length=271 Score = 74.7 bits (182), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 43/135 (32%), Positives = 73/135 (55%), Gaps = 1/135 (0%) Query 120 VSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGD 179 ++R N V + F+D+ G + + GD A + LL + + + + GGH++K GD Sbjct 91 LARLTKNGSVVIFFSDIQGSTALNEELGDRAWVKLLERHEKLIRQCVDAHGGHVIKSQGD 150 Query 180 GIMAVFRNPTVALRAVLVAQDAVKSLE-VQGYTPRMRIGIHTGRPQRLAADWLGVDVNIA 238 G M F P A+ + Q+A+ +L + + R+RIGIH G+ R D G +V +A Sbjct 151 GFMVAFSRPDQAVLCSMEIQNALDTLSWSRRHAIRVRIGIHMGKSVRRGDDLFGRNVALA 210 Query 239 ARVMERATKGGIMIS 253 ARV ++A+ G ++S Sbjct 211 ARVADQASGGETLVS 225 >gi|240173219|ref|ZP_04751877.1| hydrolase [Mycobacterium kansasii ATCC 12478] Length=443 Score = 73.9 bits (180), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/187 (35%), Positives = 91/187 (49%), Gaps = 17/187 (9%) Query 114 QALTEAVSRRPANPEVTLV-FTDLVGFSTWSLHAGDDATL-TLLRQVARAVESPLLDAGG 171 + + E S RP + V FTD+VG ST L A DA L RAV+ L GG Sbjct 272 EFVCEKPSERPDERILKAVMFTDIVG-STEQLSATGDAHWRHQLDAHDRAVDWLLAKYGG 330 Query 172 HIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWL 231 H K GDGI A+F PT A+R L D V +L +G ++R G+H G +R +W Sbjct 331 HRAKHTGDGIFALFDGPTKAVRCAL---DLVPTLATRGI--QIRAGVHVGECERRGEEWS 385 Query 232 GVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDL 291 G+ V+ ARV A G ++ S+ DL S L + +R++ G+P + Sbjct 386 GMAVHTGARVGALAGAGEVVASRTVRDLSAGSGLSFESLGPQRLK---------GLPEAV 436 Query 292 AIYRIKT 298 +YR+ T Sbjct 437 EVYRVTT 443 >gi|85858076|ref|YP_460278.1| HD domain-containing protein [Syntrophus aciditrophicus SB] gi|85721167|gb|ABC76110.1| HD domain protein [Syntrophus aciditrophicus SB] Length=660 Score = 73.2 bits (178), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 61/204 (30%), Positives = 97/204 (48%), Gaps = 27/204 (13%) Query 123 RPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIM 182 R ++++F+DL F+T+S + + +T L ++ +E+ LL+ HI K +GDGIM Sbjct 196 RTEKRNISVLFSDLKSFTTFSEASQPEIVVTQLNRLFAEMETILLEYKAHIDKYMGDGIM 255 Query 183 AVFRNPT----VALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGR-------PQRLAADWL 231 A F PT AL AV+ A + + +MRIGI TG +R + L Sbjct 256 AEFGAPTHYDRHALMAVMAAMKMQNWVRSSDFPLKMRIGIATGEAIVGLIGQKRQSYTAL 315 Query 232 GVDVNIAARVMERATKGGIMISQPTLDLIPQSELDALGVVARRV-RKPVFASKPTGIPPD 290 G VN+A+R+ +R T+G + I + T + V R V KP+ A + P Sbjct 316 GDVVNLASRIEQRCTEGLVTIDETTYE-----------AVNRYVAAKPLIAQQADTSDPG 364 Query 291 LAIYRIKTVSESTAADNFDEMSPD 314 L+ K + E N +E P+ Sbjct 365 LS----KQIEECAIRLNTNENDPE 384 >gi|218674331|ref|ZP_03524000.1| adenylate/guanylate cyclase [Rhizobium etli GR56] Length=583 Score = 73.2 bits (178), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 54/137 (40%), Positives = 77/137 (57%), Gaps = 6/137 (4%) Query 135 DLVGFSTWSLHAGDDATLTLLRQVARAVESP-LLDAGGHIVKRLGDGIMAVFRNPTVALR 193 DLVG+S + A ++ T++ LR V P +++ GG IVK +GDG++ F +P +A+R Sbjct 4 DLVGYSRL-MAADEEGTISRLRDARTNVIDPAIMEGGGRIVKTMGDGLLVEFPSPVLAVR 62 Query 194 AVLVAQDAVKSLEV---QGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERATKGGI 250 A L+ Q + S E + R RIGIH G D LG VNI AR+ A GGI Sbjct 63 AALLMQRNLISRESPQREDQRLRFRIGIHLGDVVIDGDDILGDCVNITARLETIAPAGGI 122 Query 251 MISQPTLDLIPQSELDA 267 IS+ D + QS++DA Sbjct 123 CISRAIYDHV-QSKIDA 138 >gi|339504305|ref|YP_004691725.1| adenylate cyclase [Roseobacter litoralis Och 149] gi|338758298|gb|AEI94762.1| putative adenylate cyclase [Roseobacter litoralis Och 149] Length=562 Score = 72.4 bits (176), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 67/196 (35%), Positives = 92/196 (47%), Gaps = 21/196 (10%) Query 128 EVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGG-HIVKRLGDGIMAVFR 186 + ++ D+VG+S + ATL LR V + P + AGG I+KRLGDG +A F Sbjct 7 KTVILAADIVGYSR-MMEVDHGATLEALRNVRDTIVEPCIAAGGGTIIKRLGDGWLAAFD 65 Query 187 NPTVALRAVLVAQDAVKSLEVQGYTPRMRIGIHTGRPQRLAADWLGVDVNIAARVMERAT 246 + A + + QD L P +RIGIH G + D G VNIA+R+ A Sbjct 66 GCSDACASAIKIQD----LLADDGAPELRIGIHEGPASFVDEDVFGTGVNIASRLEALAK 121 Query 247 KGGIMISQP-----TLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRIKTVSE 301 GGI IS ++DL E +A V + + +PV GIPP SE Sbjct 122 PGGIAISDAVFVNLSIDLRVSFE-NAGARVLKNIAEPVKVWAFGGIPP------TAMTSE 174 Query 302 --STAADNF-DEMSPD 314 S +NF +E SPD Sbjct 175 PISILLENFVEEASPD 190 >gi|222082394|ref|YP_002541759.1| adenylate/guanylate cyclase protein [Agrobacterium radiobacter K84] gi|221727073|gb|ACM30162.1| adenylate/guanylate cyclase protein [Agrobacterium radiobacter K84] Length=1008 Score = 72.0 bits (175), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/206 (30%), Positives = 96/206 (47%), Gaps = 29/206 (14%) Query 103 REVGLSVL----QVWQALTEAVSRRPANPE-----VTLVFTDLVGFSTWSLHAGDDATLT 153 +E+G+ L ++ L+E VS PANP +T++F DLVG + W+ G +A Sbjct 49 KEIGVYSLGHRRKILTHLSERVSHNPANPRAELRYITVLFCDLVGSTQWAELLGAEAFWD 108 Query 154 LLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNPTV----ALRAVLVAQDAVKSLEVQG 209 LL AV ++ GG++ + GDG++ F P ALR VL A AV+ ++ Sbjct 109 LLASYYAAVREAVIPLGGYVAQYHGDGVLVYFGYPNTLEDAALRGVLGASHAVEQVDKLP 168 Query 210 YTPRMRI--------------GIHTGRPQRLAADWLGVDVNIAARVMERATKGGIMISQP 255 T +R+ G+ Q G VN+AAR+ A G +++S+ Sbjct 169 NTAGIRLAARAGVTSGPVLMDGLSEAGHQGEIGQAFGATVNMAARLQSVAQPGKVVVSES 228 Query 256 TLDLIPQS-ELDALGVVARR-VRKPV 279 T L+ +L LG+ + + V KP Sbjct 229 TAALVKHHVQLHPLGIHSLKGVEKPC 254 >gi|218662623|ref|ZP_03518553.1| adenylate/guanylate cyclase protein [Rhizobium etli IE4771] Length=468 Score = 71.2 bits (173), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 67/227 (30%), Positives = 104/227 (46%), Gaps = 20/227 (8%) Query 48 TVNRSPGLVSFI---HRARRLLPGDPEFGDPLSTAGEGGPRAAARAADRLLRDRDAASRE 104 TV PGL+ H RR++P GD L G R A A RLL ++ Sbjct 225 TVTLRPGLLRLTLENHTDRRVVPNVCIAGDDLHDLL--GRRRAFLTAKRLLTNQ------ 276 Query 105 VGLSVLQVWQALTEAVSRRPANPEVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVES 164 S +++ T V +R +T +FTDL G + GD A L+R R + Sbjct 277 ---SFRDIYRTDTLDVDQRLKITSLTFLFTDLRGSTALYERVGDLAAFDLVRAHFRVLHE 333 Query 165 PLLDAGGHIVKRLGDGIMAVFRNPTVALRAVLVAQDAVKSLEVQGYTPR--MRIGIHTGR 222 + G +VK +GD +MA F +P A+ A L ++A++ L + + ++IGIH G Sbjct 334 IVATEAGAVVKTIGDAVMATFPSPDRAVAAALRMREAMRRLNAEHGSEDLLLKIGIHEGP 393 Query 223 PQRLA----ADWLGVDVNIAARVMERATKGGIMISQPTLDLIPQSEL 265 + D+ G VNIA+RV A IM ++ ++ + SE+ Sbjct 394 CLAVNLNDRQDYFGQTVNIASRVQGLADPNVIMTTEAIVEDVNVSEI 440 >gi|257059165|ref|YP_003137053.1| adenylate/guanylate cyclase with GAF sensor(s) [Cyanothece sp. PCC 8802] gi|256589331|gb|ACV00218.1| adenylate/guanylate cyclase with GAF sensor(s) [Cyanothece sp. PCC 8802] Length=584 Score = 71.2 bits (173), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 70/232 (31%), Positives = 100/232 (44%), Gaps = 55/232 (23%) Query 109 VLQVWQALTEAVSRR--PAN---------------PE---VTLVFTDLVGFSTWSLHAGD 148 V Q+ Q LTE+V +R PA+ PE VT++FTDLVGF+ + G Sbjct 361 VKQLNQYLTESVLKRFLPASIVNRVAAGELILDLRPEPRLVTILFTDLVGFTPLASQLGT 420 Query 149 DATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRNP------TVALRAVLVAQDAV 202 TLL + + S + D GG + K +GDG+MA+F P RA+ A+ Sbjct 421 QGIATLLNEYLEGMTSAVFDYGGTVDKFMGDGVMALFGAPEDLEPAEQVYRAIASARGMH 480 Query 203 KSL-------EVQGYTP---RMRIGIHTGRP--------QRLAADWLGVDVNIAARVMER 244 + L + QG R R GIH G QR +G VNIA R+ E Sbjct 481 RQLDSLNQQWQAQGLIEEPIRFRCGIHQGNAVVGMFGGGQRSDYTAIGPAVNIADRLQEV 540 Query 245 ATKGGIMISQPTLDLIPQSELDALGVVARRVRKPVFASKPTGIPPDLAIYRI 296 A I++SQ + SE+ +PV + K GI + I+ + Sbjct 541 AQADTILVSQTVAQFLKPSEI-----------QPVQSLKLKGIEESILIFSV 581 >gi|332527901|ref|ZP_08403938.1| adenylate cyclase [Rubrivivax benzoatilyticus JA2] gi|332112478|gb|EGJ12271.1| adenylate cyclase [Rubrivivax benzoatilyticus JA2] Length=318 Score = 70.5 bits (171), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 40/144 (28%), Positives = 75/144 (53%), Gaps = 9/144 (6%) Query 128 EVTLVFTDLVGFSTWSLHAGDDATLTLLRQVARAVESPLLDAGGHIVKRLGDGIMAVFRN 187 ++T++F DL G + G+ +++ ++ P+ D GGH+VK LGDG+MAVF Sbjct 6 DLTVLFADLRGSTALYETLGNAEATSVVTHCVGSLTRPVADFGGHVVKTLGDGLMAVFPR 65 Query 188 PTVALRAVLVAQDAVKSLEVQGYTP---------RMRIGIHTGRPQRLAADWLGVDVNIA 238 PT AL+A + + + + +G+ +++I + G +A D G VN+A Sbjct 66 PTSALQAAALIHEVLDGITSRGHQHGASTGLRDLKLQIAMARGEVVEMAGDCYGDAVNVA 125 Query 239 ARVMERATKGGIMISQPTLDLIPQ 262 AR+++ A +++ L +P+ Sbjct 126 ARLLDHAGDNETLVTAEVLQGLPE 149 Lambda K H 0.318 0.133 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 549222890922 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40