BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1663 Length=502 Score E Sequences producing significant alignments: (Bits) Value gi|15608801|ref|NP_216179.1| polyketide synthase pks17 [Mycobact... 1006 0.0 gi|167969220|ref|ZP_02551497.1| putative polyketide synthase Pks... 1005 0.0 gi|289443121|ref|ZP_06432865.1| polyketide synthase pks17 [Mycob... 1004 0.0 gi|148822872|ref|YP_001287626.1| polyketide synthase pks17 [Myco... 1002 0.0 gi|340626668|ref|YP_004745120.1| polyketide synthase PKS8 [Mycob... 999 0.0 gi|289753754|ref|ZP_06513132.1| polyketide synthase pks17 [Mycob... 946 0.0 gi|118463404|ref|YP_882293.1| RifB protein [Mycobacterium avium ... 600 1e-169 gi|8927425|gb|AAF82076.1|AF232752_1 polyketide synthase 7 [Mycob... 599 3e-169 gi|254775560|ref|ZP_05217076.1| RifB protein [Mycobacterium aviu... 597 1e-168 gi|336457822|gb|EGO36816.1| polyketide synthase family protein [... 597 2e-168 gi|41407468|ref|NP_960304.1| Pks7 [Mycobacterium avium subsp. pa... 596 3e-168 gi|342860755|ref|ZP_08717405.1| RifB protein [Mycobacterium colo... 590 2e-166 gi|240173376|ref|ZP_04752034.1| polyketide synthase Pks7 [Mycoba... 587 1e-165 gi|254820900|ref|ZP_05225901.1| erythronolide synthase, modules ... 583 2e-164 gi|342860754|ref|ZP_08717404.1| erythronolide synthase, modules ... 578 5e-163 gi|183982486|ref|YP_001850777.1| polyketide synthase, Pks8 [Myco... 577 2e-162 gi|296164560|ref|ZP_06847130.1| polyketide synthase [Mycobacteri... 575 4e-162 gi|296164561|ref|ZP_06847131.1| erythronolide synthase, modules ... 575 6e-162 gi|254820901|ref|ZP_05225902.1| Pks7 [Mycobacterium intracellula... 570 2e-160 gi|183982485|ref|YP_001850776.1| polyketide synthase Pks7 [Mycob... 561 9e-158 gi|240170122|ref|ZP_04748781.1| polyketide synthase, Pks8 [Mycob... 560 2e-157 gi|289753751|ref|ZP_06513129.1| polyketide synthase [Mycobacteri... 560 3e-157 gi|118462561|ref|YP_882292.1| erythronolide synthase, modules 3 ... 558 7e-157 gi|289757768|ref|ZP_06517146.1| polyketide synthase pks7 [Mycoba... 558 7e-157 gi|308376784|ref|ZP_07668350.1| putative phosphopantetheine atta... 557 1e-156 gi|289447274|ref|ZP_06437018.1| polyketide synthase pks7 [Mycoba... 553 2e-155 gi|308401191|ref|ZP_07493357.2| putative acyl transferase domain... 553 3e-155 gi|306788762|ref|ZP_07427084.1| polyketide synthase pks7 [Mycoba... 553 3e-155 gi|340626667|ref|YP_004745119.1| putative polyketide synthase PK... 553 4e-155 gi|289745901|ref|ZP_06505279.1| polyketide synthase pks7 [Mycoba... 553 4e-155 gi|15608799|ref|NP_216177.1| polyketide synthase pks7 [Mycobacte... 553 4e-155 gi|298525160|ref|ZP_07012569.1| polyketide synthase pks7 [Mycoba... 552 4e-155 gi|289574330|ref|ZP_06454557.1| polyketide synthase pks7 [Mycoba... 552 4e-155 gi|31792848|ref|NP_855341.1| polyketide synthase pks7 [Mycobacte... 552 4e-155 gi|254231859|ref|ZP_04925186.1| polyketide synthase pks7 [Mycoba... 550 3e-154 gi|254550672|ref|ZP_05141119.1| polyketide synthase pks17 [Mycob... 524 2e-146 gi|254550671|ref|ZP_05141118.1| polyketide synthase pks17 [Mycob... 493 5e-137 gi|183980137|ref|YP_001848428.1| polyketide synthase PKS [Mycoba... 480 2e-133 gi|240171787|ref|ZP_04750446.1| putative polyketide synthase [My... 465 1e-128 gi|254552020|ref|ZP_05142467.1| polyketide synthase pks1 [Mycoba... 464 2e-128 gi|289444505|ref|ZP_06434249.1| probable polyketide synthase pks... 464 2e-128 gi|289448613|ref|ZP_06438357.1| polyketide synthase PKS1 [Mycoba... 463 3e-128 gi|340627935|ref|YP_004746387.1| putative polyketide synthase PK... 463 3e-128 gi|294993968|ref|ZP_06799659.1| putative polyketide synthase [My... 462 4e-128 gi|240170497|ref|ZP_04749156.1| polyketide synthase, Pks12 [Myco... 462 5e-128 gi|289575652|ref|ZP_06455879.1| polyketide synthase pks1 [Mycoba... 462 5e-128 gi|289746746|ref|ZP_06506124.1| polyketide synthase PKS1 [Mycoba... 462 5e-128 gi|339295785|gb|AEJ47896.1| polyketide synthase PKS1 [Mycobacter... 462 5e-128 gi|167970038|ref|ZP_02552315.1| putative polyketide synthase pks... 462 6e-128 gi|289755061|ref|ZP_06514439.1| polyketide synthase pks1 [Mycoba... 462 6e-128 >gi|15608801|ref|NP_216179.1| polyketide synthase pks17 [Mycobacterium tuberculosis H37Rv] gi|15841119|ref|NP_336156.1| polyketide synthase, putative [Mycobacterium tuberculosis CDC1551] gi|31792850|ref|NP_855343.1| polyketide synthase pks17 [Mycobacterium bovis AF2122/97] 46 more sequence titles Length=502 Score = 1006 bits (2600), Expect = 0.0, Method: Compositional matrix adjust. Identities = 502/502 (100%), Positives = 502/502 (100%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP Sbjct 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV Sbjct 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 481 DEDITTATESQLFAILDDELGP 502 >gi|167969220|ref|ZP_02551497.1| putative polyketide synthase Pks17 [Mycobacterium tuberculosis H37Ra] gi|253799297|ref|YP_003032298.1| polyketide synthase pks17 [Mycobacterium tuberculosis KZN 1435] gi|298525163|ref|ZP_07012572.1| polyketide synthase 7 [Mycobacterium tuberculosis 94_M4241A] 12 more sequence titles Length=510 Score = 1005 bits (2598), Expect = 0.0, Method: Compositional matrix adjust. Identities = 502/502 (100%), Positives = 502/502 (100%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 9 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 68 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 69 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 128 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 129 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 188 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 189 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 248 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP Sbjct 249 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 308 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 309 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 368 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV Sbjct 369 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 428 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 429 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 488 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 489 DEDITTATESQLFAILDDELGP 510 >gi|289443121|ref|ZP_06432865.1| polyketide synthase pks17 [Mycobacterium tuberculosis T46] gi|289750218|ref|ZP_06509596.1| polyketide synthase pks17 [Mycobacterium tuberculosis T92] gi|289416040|gb|EFD13280.1| polyketide synthase pks17 [Mycobacterium tuberculosis T46] gi|289690805|gb|EFD58234.1| polyketide synthase pks17 [Mycobacterium tuberculosis T92] Length=502 Score = 1004 bits (2596), Expect = 0.0, Method: Compositional matrix adjust. Identities = 501/502 (99%), Positives = 502/502 (100%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMS+VGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP Sbjct 241 ASAMTEHLGERDRVRMSQVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV Sbjct 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 481 DEDITTATESQLFAILDDELGP 502 >gi|148822872|ref|YP_001287626.1| polyketide synthase pks17 [Mycobacterium tuberculosis F11] gi|148721399|gb|ABR06024.1| polyketide synthase pks17 [Mycobacterium tuberculosis F11] Length=502 Score = 1002 bits (2591), Expect = 0.0, Method: Compositional matrix adjust. Identities = 501/502 (99%), Positives = 501/502 (99%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAEL Sbjct 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELR 300 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV Sbjct 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 481 DEDITTATESQLFAILDDELGP 502 >gi|340626668|ref|YP_004745120.1| polyketide synthase PKS8 [Mycobacterium canettii CIPT 140010059] gi|340004858|emb|CCC44003.1| polyketide synthase PKS8 [Mycobacterium canettii CIPT 140010059] Length=2105 Score = 999 bits (2584), Expect = 0.0, Method: Compositional matrix adjust. Identities = 500/502 (99%), Positives = 501/502 (99%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 1604 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 1663 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 1664 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 1723 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTP+RVDKVLRAKVDGAWNLH Sbjct 1724 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPDRVDKVLRAKVDGAWNLH 1783 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 1784 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 1843 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP Sbjct 1844 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 1903 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 1904 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 1963 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV Sbjct 1964 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 2023 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 TVDQPNPSTRFNEVT ELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 2024 TVDQPNPSTRFNEVTGELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 2083 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 2084 DEDITTATESQLFAILDDELGP 2105 >gi|289753754|ref|ZP_06513132.1| polyketide synthase pks17 [Mycobacterium tuberculosis EAS054] gi|289694341|gb|EFD61770.1| polyketide synthase pks17 [Mycobacterium tuberculosis EAS054] Length=502 Score = 946 bits (2446), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/502 (98%), Positives = 488/502 (98%), Gaps = 0/502 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ Sbjct 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 Query 241 ASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 ASAMTEHLGERDRVRMS+VGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP Sbjct 241 ASAMTEHLGERDRVRMSQVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELP 300 Query 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE Sbjct 301 ALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTE 360 Query 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAV 420 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAE P Sbjct 361 IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAETPRHPAGERPCR 420 Query 421 TVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 QPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD Sbjct 421 HDSQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHD 480 Query 481 DEDITTATESQLFAILDDELGP 502 DEDITTATESQLFAILDDELGP Sbjct 481 DEDITTATESQLFAILDDELGP 502 >gi|118463404|ref|YP_882293.1| RifB protein [Mycobacterium avium 104] gi|48928158|gb|AAT47757.1| possible polyketide synthase [Mycobacterium avium] gi|118164691|gb|ABK65588.1| RifB protein [Mycobacterium avium 104] Length=2124 Score = 600 bits (1548), Expect = 1e-169, Method: Compositional matrix adjust. Identities = 328/519 (64%), Positives = 383/519 (74%), Gaps = 23/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKVVLT+P Sbjct 1610 MEAGPDRTAAMLAEIVGLLRAGVLTPLPLKTFDVRCASTAYRYVSQARHIGKVVLTVPSG 1669 Query 61 -----------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A TVLITGGTGMAGSA+ARHLV RY V VVL SR G A LV Sbjct 1670 PGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGAAELV 1729 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVD 166 DEL AGA V++CDV DRDAVA ++A P L + HAAG+LDD +++ LTP+RVD Sbjct 1730 DELQRAGASASVLACDVGDRDAVATMLAGLPSGYPLRGIVHAAGILDDGLLSSLTPDRVD 1789 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELT+ LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ Sbjct 1790 AVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAD 1849 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + PV+VA Sbjct 1850 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVA 1909 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 ARLDRAAL+ A LP L +L AGP RR+ID AD S SGLA+RLHGL+PE R REL Sbjct 1910 ARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSPEARRRELV 1969 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG +I+A +AFQDLGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 1970 DLVCGNAAMVLGVPDPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 2029 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LAEHLD +LA + DQP+ RFN++TRELQALL P+WN DDK L R+ + Sbjct 2030 PVVLAEHLDSRLAGSGG--DDQPDLMGRFNDITRELQALLGAPHWNSDDKAVLRARIHGL 2087 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A PA GP + DED+ ATESQLFAILD+ELG Sbjct 2088 L---GALPAGDGPDSAPLDEDLEAATESQLFAILDEELG 2123 >gi|8927425|gb|AAF82076.1|AF232752_1 polyketide synthase 7 [Mycobacterium avium subsp. paratuberculosis] Length=678 Score = 599 bits (1545), Expect = 3e-169, Method: Compositional matrix adjust. Identities = 327/519 (64%), Positives = 383/519 (74%), Gaps = 23/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKVVLT+P Sbjct 164 MEAGPDRTAAMLAEIVGLLQEGVLTPLPLKTFDVRCASAAYRYVSQARHIGKVVLTVPSG 223 Query 61 W-----------AAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A TVLITGGTGMAGSA+ARHLV RY V VVL SR G A LV Sbjct 224 LGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGAAELV 283 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVD 166 DEL AGA V++CDVADRDAVA ++A P L + HAAG+LDD +++ L P+RVD Sbjct 284 DELQRAGASASVLACDVADRDAVATMLAGLPAGYPLRGIVHAAGILDDGLLSSLIPDRVD 343 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELT+ LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ Sbjct 344 AVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAD 403 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + PV+VA Sbjct 404 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVA 463 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 ARLDRAAL+ A LP L +L AGP RR+ID AD S SGLA+RLHGL+PE R REL Sbjct 464 ARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSPEARRRELV 523 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG + +I+A +AFQDLGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 524 DLVCGNAAMVLGVPNPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 583 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LAEHLD +LA + DQP+ RFN++TRELQALL +WN DDK L R+ + Sbjct 584 PVVLAEHLDSRLAGSGG--DDQPDLMGRFNDITRELQALLGAAHWNSDDKAVLRTRIHGL 641 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A PA GP + DED+ ATESQLFAILD+ELG Sbjct 642 L---GALPAGDGPDSAPLDEDLEAATESQLFAILDEELG 677 >gi|254775560|ref|ZP_05217076.1| RifB protein [Mycobacterium avium subsp. avium ATCC 25291] Length=2124 Score = 597 bits (1540), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 327/519 (64%), Positives = 383/519 (74%), Gaps = 23/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEA P R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKVVLT+P Sbjct 1610 MEACPDRTAAMLAEIVGLLRAGVLTPLPLKTFDVRCASAAYRYVSQARHIGKVVLTVPSG 1669 Query 61 -----------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A TVLITGGTGMAGSA+ARHLV RY V V L SR G A LV Sbjct 1670 PGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVALVSRTGAQAAGAAELV 1729 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVD 166 DEL AGA V++CDVADRDAVA ++A P L + HAAG+LDD +++ LTP+RVD Sbjct 1730 DELKRAGASASVLACDVADRDAVATMLAGLPAGYPLRGIVHAAGILDDGLLSSLTPDRVD 1789 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELT+ LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ Sbjct 1790 AVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAD 1849 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + PV+VA Sbjct 1850 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVA 1909 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 ARLDRAAL+ A LP L +L AGP RR+ID AD S SGLA+RLHGL+PE R REL Sbjct 1910 ARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSPEARRRELV 1969 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG + +I+A +AFQDLGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 1970 DLVCGNAAMVLGVPNPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 2029 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LAEHLD +LA + DQP+ RFN++TRELQALL P+WN DDK L R+ + Sbjct 2030 PVVLAEHLDSRLAGSGG--DDQPDLMGRFNDITRELQALLGAPHWNSDDKAVLRARIHGL 2087 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A PA GP + DED+ ATESQLFAILD+ELG Sbjct 2088 L---GALPAGDGPDSAPLDEDLEAATESQLFAILDEELG 2123 >gi|336457822|gb|EGO36816.1| polyketide synthase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=1941 Score = 597 bits (1538), Expect = 2e-168, Method: Compositional matrix adjust. Identities = 327/519 (64%), Positives = 383/519 (74%), Gaps = 23/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKVVLT+P Sbjct 1427 MEAGPDRTAAMLAEIVGLLQEGVLTPLPLKTFDVRCASAAYRYVSQARHIGKVVLTVPSG 1486 Query 61 W-----------AAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A TVLITGGTGMAGSA+ARHLV RY V VVL SR G A LV Sbjct 1487 LGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGAAELV 1546 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVD 166 DEL AGA V++CDVADRDAVA ++A P L + HAAG+LDD +++ L P+RVD Sbjct 1547 DELQRAGASASVLACDVADRDAVATMLAGLPAGYPLRGIVHAAGILDDGLLSSLIPDRVD 1606 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELT+ LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ Sbjct 1607 AVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAD 1666 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + PV+VA Sbjct 1667 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVA 1726 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 ARLDRAAL+ A LP L +L AGP RR+ID AD S SGLA+RLHGL+PE R REL Sbjct 1727 ARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSPEARRRELV 1786 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG + +I+A +AFQDLGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 1787 DLVCGNAAMVLGVPNPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 1846 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LAEHLD +LA + DQP+ RFN++TRELQALL +WN DDK L R+ + Sbjct 1847 PVVLAEHLDSRLAGSGG--DDQPDLMGRFNDITRELQALLGAAHWNSDDKAVLRTRIHGL 1904 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A PA GP + DED+ ATESQLFAILD+ELG Sbjct 1905 L---GALPAGDGPDSAPLDEDLEAATESQLFAILDEELG 1940 >gi|41407468|ref|NP_960304.1| Pks7 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395820|gb|AAS03687.1| Pks7 [Mycobacterium avium subsp. paratuberculosis K-10] Length=2018 Score = 596 bits (1537), Expect = 3e-168, Method: Compositional matrix adjust. Identities = 327/519 (64%), Positives = 383/519 (74%), Gaps = 23/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKVVLT+P Sbjct 1504 MEAGPDRTAAMLAEIVGLLQEGVLTPLPLKTFDVRCASAAYRYVSQARHIGKVVLTVPSG 1563 Query 61 W-----------AAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A TVLITGGTGMAGSA+ARHLV RY V VVL SR G A LV Sbjct 1564 LGEVLSGCGGGLAQSTVLITGGTGMAGSALARHLVDRYRVGHVVLVSRTGAQAAGAAELV 1623 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVD 166 DEL AGA V++CDVADRDAVA ++A P L + HAAG+LDD +++ L P+RVD Sbjct 1624 DELQRAGASASVLACDVADRDAVATMLAGLPAGYPLRGIVHAAGILDDGLLSSLIPDRVD 1683 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELT+ LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ Sbjct 1684 AVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAD 1743 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + PV+VA Sbjct 1744 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVA 1803 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 ARLDRAAL+ A LP L +L AGP RR+ID AD S SGLA+RLHGL+PE R REL Sbjct 1804 ARLDRAALSENIAALPPLLRELAAGPTRRVIDDADVTASMSGLAARLHGLSPEARRRELV 1863 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG + +I+A +AFQDLGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 1864 DLVCGNAAMVLGVPNPADINAGRAFQDLGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 1923 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LAEHLD +LA + DQP+ RFN++TRELQALL +WN DDK L R+ + Sbjct 1924 PVVLAEHLDSRLAGSGG--DDQPDLMGRFNDITRELQALLGAAHWNSDDKAVLRTRIHGL 1981 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A PA GP + DED+ ATESQLFAILD+ELG Sbjct 1982 L---GALPAGDGPDSAPLDEDLEAATESQLFAILDEELG 2017 >gi|342860755|ref|ZP_08717405.1| RifB protein [Mycobacterium colombiense CECT 3035] gi|342131779|gb|EGT85036.1| RifB protein [Mycobacterium colombiense CECT 3035] Length=2129 Score = 590 bits (1521), Expect = 2e-166, Method: Compositional matrix adjust. Identities = 322/519 (63%), Positives = 380/519 (74%), Gaps = 22/519 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP R A MLAE+V L + L LP+K++DVR A AYR++SQARH+GKV LT+ Sbjct 1614 MEAGPDRTAAMLAEIVGLLTADVLKPLPLKTFDVRCASAAYRYVSQARHIGKVALTVGSG 1673 Query 61 -----------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A +V+ITGGTGMAGSA+ARHLV RY V VVL SR G V LV Sbjct 1674 PGEVLSGCGGGLADASVVITGGTGMAGSALARHLVDRYRVAHVVLVSRTGARAAGVDELV 1733 Query 110 DELGSAGARVQVVSCDVADRDAVAGL---VASQPDLTAVFHAAGVLDDAVITGLTPERVD 166 L +AGA+V VV+CDVAD +A + + + +Q L + HAAG+LDD +I+ LTP+RVD Sbjct 1734 AGLQNAGAQVSVVACDVADPEAASAMLTQIPAQYPLRGIVHAAGILDDGLISSLTPDRVD 1793 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLHELTRHLD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGLAAYRR+ Sbjct 1794 AVLRAKVDGAWNLHELTRHLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLAAYRRAH 1853 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPL T QA+ DAA+L + P++VA Sbjct 1854 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLSTEQALAAFDAAMLVETPMLVA 1913 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIIDGAD-EVSGSGLASRLHGLTPEQRHRELT 343 AR+DRAAL+ A LP L +LVAGP RR+ID D S +GLA+RLHGLTPE R REL Sbjct 1914 ARVDRAALSDNIAALPPLLRELVAGPTRRVIDDTDVSASSTGLAARLHGLTPEARQRELV 1973 Query 344 ELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 +LVC NAA+VLG + +IDA +AFQ+LGFDSLTAVELRNRLK ATGLTL PTLIFDYPT Sbjct 1974 DLVCGNAAMVLGVPNPADIDAGRAFQELGFDSLTAVELRNRLKNATGLTLSPTLIFDYPT 2033 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 LA HLD QLA A DQPN RFN++TRELQALL P WN DDK+ L R+ + Sbjct 2034 PTVLAAHLDTQLAGT-AGAGDQPNLMGRFNDITRELQALLGAPTWNADDKSVLRARIHNL 2092 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L A P H D+D+ ATESQLFAILD+ELG Sbjct 2093 L---AALPPGDDSDAEHLDDDLDAATESQLFAILDEELG 2128 >gi|240173376|ref|ZP_04752034.1| polyketide synthase Pks7 [Mycobacterium kansasii ATCC 12478] Length=1641 Score = 587 bits (1514), Expect = 1e-165, Method: Compositional matrix adjust. Identities = 324/511 (64%), Positives = 380/511 (75%), Gaps = 26/511 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP-- 58 +EAGP RIAQML EL+ +F AL LP K++DVR AR+AYRF+SQARH+GKVVLT+ Sbjct 1146 IEAGPDRIAQMLTELMTMFAAGALQPLPAKTFDVRRARQAYRFVSQARHIGKVVLTLSES 1205 Query 59 DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGAR 118 D A GTV+ITGGTGMAG+ ARH+VSR+ V+L SR+G ++ L D+L AGA Sbjct 1206 DGLAGGTVVITGGTGMAGAVTARHVVSRHRAAHVMLVSRSGGRAHGISELADQLRDAGAG 1265 Query 119 VQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDG 175 V VV+CDVADRDAVA L+A P L VFHAAGVLDD +I LTP+R+D VLRAKVDG Sbjct 1266 VSVVACDVADRDAVAALLAQVPPQYPLRGVFHAAGVLDDGLIASLTPDRMDAVLRAKVDG 1325 Query 176 AWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAW 235 AWNLH LTR+ DVSAFVLFSSMAGI+G PGQ NYAAAN+FLDGLAAYR + GL LSVAW Sbjct 1326 AWNLHVLTRYQDVSAFVLFSSMAGIMGTPGQGNYAAANSFLDGLAAYRHAHGLPGLSVAW 1385 Query 236 GLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAAL- 294 GLWEQASAMT HLG+RD+ RMSR GLA L T QA+ LD A++ADR VVVA RLD AL Sbjct 1386 GLWEQASAMTRHLGDRDKARMSRAGLATLSTAQALELLDTAMVADRAVVVATRLDSRALG 1445 Query 295 --AGAELPALFSQLVAGPIRRIIDGADEV-SGSGLASRLHGLTPEQRHRELTELVCSNAA 351 + A LP LF +L A P RR++D AD S +GLA+RL L PE+RHREL +VCSNAA Sbjct 1446 TDSTAPLP-LFGELAARPARRVVDDADTAGSTTGLAARLRSLRPERRHRELAGVVCSNAA 1504 Query 352 IVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHL 410 VLG S T ++DA ++FQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LAEHL Sbjct 1505 TVLGRSSTADVDADRSFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPAALAEHL 1564 Query 411 DIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPP 470 D +LA A T D+ + TR N+V EL L++Q +W P+DK RL RL AIL +A Sbjct 1565 DSRLA---AGTSDEADLITRCNDVAGELDRLINQGDWAPEDKARLADRLHAILAQLSA-- 1619 Query 471 ASSGPSTTHDDEDITTATESQLFAILDDELG 501 D+DITTA+ESQLFAILD+ELG Sbjct 1620 ----------DDDITTASESQLFAILDEELG 1640 >gi|254820900|ref|ZP_05225901.1| erythronolide synthase, modules 3 and 4 [Mycobacterium intracellulare ATCC 13950] Length=2131 Score = 583 bits (1503), Expect = 2e-164, Method: Compositional matrix adjust. Identities = 322/513 (63%), Positives = 379/513 (74%), Gaps = 11/513 (2%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP RIA+MLAEL+ LF AL LPVK++D R A +AYRF+SQARH+GKVVLTMPD Sbjct 1619 MEAGPDRIAEMLAELMTLFAGGALAPLPVKAFDARSAADAYRFVSQARHIGKVVLTMPDG 1678 Query 61 ---WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 A GT LITGGTGMAGSAVARHLV R+ V V+L SR GE +A L EL GA Sbjct 1679 PAGLAGGTALITGGTGMAGSAVARHLVERHRVPHVMLVSRGGEQAAGIAELAGELRDLGA 1738 Query 118 RVQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVDKVLRAKVD 174 V VV+CDV DRDAVA L+A P L +VFHAAGV+DDA++ LTP R+D VLRAKVD Sbjct 1739 SVSVVACDVGDRDAVAALLARVPSHYPLRSVFHAAGVIDDAMVASLTPARIDAVLRAKVD 1798 Query 175 GAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVA 234 GAW+LHELT+ L ++AFV FSSMAGIVGAPGQ NYAAAN+FLD LAA+R +RGL LSVA Sbjct 1799 GAWHLHELTKELGLAAFVAFSSMAGIVGAPGQGNYAAANSFLDALAAHRHARGLPGLSVA 1858 Query 235 WGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAAL 294 WG+WE+ SAMT HLGE DR RMSR GL+ L T QA+ LDAALL DRP+VV RLDR AL Sbjct 1859 WGMWEEPSAMTHHLGEADRARMSRAGLSALSTRQALDLLDAALLGDRPMVVGTRLDRGAL 1918 Query 295 A--GAELPALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAI 352 A A LP L SQL P RR+++ D VS +GL +RL GL+PEQR EL ELVC NAA Sbjct 1919 AHHSATLPPLLSQLATRPARRVLEHTDMVSLTGLRARLDGLSPEQRQAELVELVCGNAAT 1978 Query 353 VLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDI 412 VLGH+ +++A AF DLGFDSLTAVELRNRLK ATGLTL PTLIFD+PT A LAEHL Sbjct 1979 VLGHTTADVNADDAFGDLGFDSLTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLGT 2038 Query 413 QLANAP-AVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPA 471 +LA A +P+ RF+++TRELQALL +P +P D+ +L+ RL+ +L T P Sbjct 2039 ELATGSVAAPATEPDRIARFDDITRELQALLGRPGLSPADRAQLVARLEGLLATATGPTP 2098 Query 472 SSGPSTTHD--DEDITTATESQLFAILDDELGP 502 S+ P D D+D+ TATESQLFAILDDE+GP Sbjct 2099 SALPDQPEDAFDDDLATATESQLFAILDDEVGP 2131 >gi|342860754|ref|ZP_08717404.1| erythronolide synthase, modules 3 and 4 [Mycobacterium colombiense CECT 3035] gi|342131778|gb|EGT85035.1| erythronolide synthase, modules 3 and 4 [Mycobacterium colombiense CECT 3035] Length=2121 Score = 578 bits (1491), Expect = 5e-163, Method: Compositional matrix adjust. Identities = 328/518 (64%), Positives = 378/518 (73%), Gaps = 17/518 (3%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP RIA+MLAEL++LF L LPVK +D R A +AYRF+SQARHVGKVVLTMPD Sbjct 1605 MEAGPDRIAEMLAELMDLFARGVLMPLPVKEFDARSAADAYRFVSQARHVGKVVLTMPDG 1664 Query 61 ---WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 A GT LITGGTGMAGSAVARHLV R+ V V+L SR+GE +A L EL GA Sbjct 1665 PAGLAGGTALITGGTGMAGSAVARHLVERHRVPHVLLVSRSGERAGGMADLAAELRELGA 1724 Query 118 RVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVD 174 V V +CDV DRDAVA L+A P L +VFHAAGVLDDAV+ LTP R+D VLRAKVD Sbjct 1725 SVSVAACDVGDRDAVAELLAQVPARYPLRSVFHAAGVLDDAVLASLTPARIDTVLRAKVD 1784 Query 175 GAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVA 234 GAWNLHELT L++SAFV FSSMAGIVGAPGQ NYAAAN+FLD LAA+RR+RGL LSVA Sbjct 1785 GAWNLHELTGGLNLSAFVAFSSMAGIVGAPGQGNYAAANSFLDALAAHRRTRGLPGLSVA 1844 Query 235 WGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAAL 294 WG+WE+ S MT+HLGERD+ RMSR GL+ L T QA+ LDAALL ++P+VVA RLDRAAL Sbjct 1845 WGMWEETSTMTQHLGERDKARMSRAGLSALSTRQALELLDAALLTEQPMVVATRLDRAAL 1904 Query 295 A--GAELPALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAI 352 A G LP L SQL P RR+++ D VS +GL +RL G+TP+QRH EL ELVCSNAA Sbjct 1905 AHHGDTLPPLLSQLATRPARRVLEHTDMVSLTGLRARLEGMTPDQRHSELVELVCSNAAT 1964 Query 353 VLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDI 412 VLGHS +++A AF DLGFDSLTAVELRNRLK ATGLTL PTLIFD PT LAEHL Sbjct 1965 VLGHSFADVNADDAFGDLGFDSLTAVELRNRLKIATGLTLSPTLIFDQPTPGALAEHLGA 2024 Query 413 QLANA-----PAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 QLA + P+ RFN++ RELQALL QP+ +P DK +LI RL+ +L T Sbjct 2025 QLAGSAPGAPAIGAAAAPDRMARFNDIARELQALLGQPDLSPGDKAQLITRLEGLLAAAT 2084 Query 468 A---PPASSGPSTTHDDEDITTATESQLFAILDDELGP 502 P P+ DD DI TATESQLFAILD+E GP Sbjct 2085 GRAQAPLLEHPADAFDD-DIATATESQLFAILDEEAGP 2121 >gi|183982486|ref|YP_001850777.1| polyketide synthase, Pks8 [Mycobacterium marinum M] gi|183175812|gb|ACC40922.1| polyketide synthase, Pks8 [Mycobacterium marinum M] Length=2114 Score = 577 bits (1486), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 312/514 (61%), Positives = 388/514 (76%), Gaps = 14/514 (2%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP IA+ML+E+V L + L P+K +DVR A++AYR++SQARH+GKVVLT+P Sbjct 1603 MEAGPDAIARMLSEVVGLLQEGILKAPPLKLFDVRSAQQAYRYVSQARHIGKVVLTLPQG 1662 Query 61 WAA------GTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 AA GTVLITGGTGMAG+AVARHLV RYGV VVL SRAG +A LV EL Sbjct 1663 PAAQSVLSGGTVLITGGTGMAGAAVARHLVQRYGVGHVVLVSRAGTQAPGIADLVAELQQ 1722 Query 115 AGARVQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V V +CDVADRDAVA L+A PD L +FHAAGVLDDAV+ LTP+RV+ VLRA Sbjct 1723 GGAQVSVTACDVADRDAVAALLAQLPDRYPLKGIFHAAGVLDDAVLASLTPDRVEPVLRA 1782 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 K GAWNLHELT +D++AFV+FSS+AGI GAPGQ NYAAANAFLDGLAAYRR + L A+ Sbjct 1783 KAAGAWNLHELTHGMDLAAFVMFSSLAGIAGAPGQGNYAAANAFLDGLAAYRRGQDLPAV 1842 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDR 291 S+AWGLWEQ S MT+HLG+RD RM +VGL PL T A+ LDAALL +RP VVAA+L+ Sbjct 1843 SIAWGLWEQPSTMTQHLGDRDLARMRQVGLDPLSTEHALHLLDAALLGERPGVVAAQLNV 1902 Query 292 AAL-AGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCSN 349 AAL A E+P ++ LV +RR++D D S + L SRLH L+PEQR REL +++C+N Sbjct 1903 AALSANPEVPPIWRDLVTRSVRRVVDANDNSASMTALISRLHTLSPEQRSRELVDMICTN 1962 Query 350 AAIVLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEH 409 AA VLG++ +IDA+K FQDLGFDSLTAVELRNRLK++TGLTL PTLIFDYPT A LAEH Sbjct 1963 AATVLGNASVDIDANKPFQDLGFDSLTAVELRNRLKSSTGLTLSPTLIFDYPTPAALAEH 2022 Query 410 LDIQLAN-APAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTA 468 L QL++ +PA +QPN RF+ V REL +++++P+W +D+ R+ RL +L D T+ Sbjct 2023 LSTQLSSLSPAAADEQPNRLARFDAVARELDSMINEPDWTAEDRERVSNRLHGLLADLTS 2082 Query 469 PPASSGPSTTHDDEDITTATESQLFAILDDELGP 502 P S G +HDD DI++A+ES+LFAILD+ELGP Sbjct 2083 -PQSRGEDHSHDD-DISSASESELFAILDEELGP 2114 >gi|296164560|ref|ZP_06847130.1| polyketide synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900084|gb|EFG79520.1| polyketide synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=769 Score = 575 bits (1483), Expect = 4e-162, Method: Compositional matrix adjust. Identities = 325/518 (63%), Positives = 382/518 (74%), Gaps = 23/518 (4%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAG R A MLAE+ L + A+ LP+K +DVR A AYRF+SQARH+GKVVLT+P Sbjct 257 LEAGADRTAAMLAEIQGLLRNCAVRPLPLKVFDVRCAPAAYRFVSQARHIGKVVLTLPGG 316 Query 61 ----------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVD 110 A G+V+ITGGTGMAGSA+ARHLV RYGV VVLASRAG VA LVD Sbjct 317 PGGVLSGCGGLAGGSVVITGGTGMAGSALARHLVERYGVAYVVLASRAGAAAAGVAELVD 376 Query 111 ELGSAGARVQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVDK 167 L AGARV VVSCDVADRDAVA ++ PD L V HAAGVLDD ++ LTP+RVD Sbjct 377 RLQEAGARVSVVSCDVADRDAVAAMLGGIPDEYPLRGVVHAAGVLDDGLVLSLTPDRVDA 436 Query 168 VLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRG 227 VLRAKVDGAW+LHELTRHLD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGL A+RR+ G Sbjct 437 VLRAKVDGAWHLHELTRHLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLVAHRRAHG 496 Query 228 LAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAA 287 LA LS+AWGLWEQASAMT HLGERD+ RMSR+G+APL T QA+ D+A+L D PV++AA Sbjct 497 LAGLSLAWGLWEQASAMTAHLGERDKARMSRLGIAPLSTEQALESFDSAMLVDAPVLMAA 556 Query 288 RLDRAALA--GAELPALFSQLVAGPIRRIIDGADEVS-GSGLASRLHGLTPEQRHRELTE 344 RLDR AL+ A LP L S+L A RR++D A + +GL +RLHGLTPE R REL + Sbjct 557 RLDRVALSDNAAALPPLLSELAARTTRRVVDDAATAALTTGLTARLHGLTPEARRRELVD 616 Query 345 LVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTA 403 LV NAA VLG + +IDA +AFQ+LGFDSLTAVELRNRLKTATGLTL PTLIFDYP+ Sbjct 617 LVRGNAATVLGLPNPADIDAGRAFQELGFDSLTAVELRNRLKTATGLTLSPTLIFDYPSP 676 Query 404 AELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAIL 463 A LAEHLD QL+ PA +P+ RF +++RELQALL +P W+ DK+ L RL +L Sbjct 677 AALAEHLDGQLSAGPA---GEPDLMARFTDISRELQALLARPGWDAGDKSALRARLHGLL 733 Query 464 TDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 T PA P D D+ TATESQLFAILD+ELG Sbjct 734 --ATLGPADH-PDPEGLDADLDTATESQLFAILDEELG 768 >gi|296164561|ref|ZP_06847131.1| erythronolide synthase, modules 3 and 4 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900085|gb|EFG79521.1| erythronolide synthase, modules 3 and 4 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=2122 Score = 575 bits (1482), Expect = 6e-162, Method: Compositional matrix adjust. Identities = 329/512 (65%), Positives = 379/512 (75%), Gaps = 12/512 (2%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP RIA+MLAEL+ LF L LPV+++D+R A +AYRF+SQARH+GKVVLTMP Sbjct 1613 MEAGPDRIAEMLAELMRLFAAGVLKPLPVRAFDIRCAADAYRFVSQARHIGKVVLTMPGG 1672 Query 61 WAAG---TVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 A T L+TGGTGMAGSAVARHLV RY V V+L SR GE V LVD L + GA Sbjct 1673 PAGLAGGTALVTGGTGMAGSAVARHLVERYRVPHVMLVSRGGERAAGVPGLVDGLRATGA 1732 Query 118 RVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVD 174 V VV+CDV D +AVAGL+A P L VFHAAGVLDDAVI LTP+RVD VLR+K D Sbjct 1733 EVTVVACDVGDPEAVAGLLARVPARFPLRGVFHAAGVLDDAVIASLTPQRVDTVLRSKAD 1792 Query 175 GAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVA 234 GAW+LHELTR LD+SAFV+FSSMAGIVGAPGQ NYAAAN+FLDGLAA+RR+ GL LSVA Sbjct 1793 GAWHLHELTRGLDLSAFVMFSSMAGIVGAPGQGNYAAANSFLDGLAAHRRAHGLPGLSVA 1852 Query 235 WGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLD--RA 292 WG+W + SAMT HLGERD+ RMSR GLA L T QA+ LDAALLA+ PVVVA RLD Sbjct 1853 WGMWAEESAMTGHLGERDKARMSRAGLAALSTGQALDLLDAALLAEPPVVVATRLDATAL 1912 Query 293 ALAGAELPALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAI 352 A AGA LP L SQL A P RR++D D VS +GL +RL GL PEQR REL ELVC NAA Sbjct 1913 AHAGAALPPLLSQLAARPARRVLDPTDMVSLTGLRARLDGLAPEQRRRELVELVCGNAAT 1972 Query 353 VLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDI 412 VLGHS ++DA +AF DLGFDSLTAVELRNRLK ATGLTL PTLIFD+PT A LAEHLD Sbjct 1973 VLGHSTADVDAEQAFADLGFDSLTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLDG 2032 Query 413 QLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPP-- 470 QLA + P+ RFN+V RELQALL +P+W+P DK +L+ RL+ +L+ P Sbjct 2033 QLAA--GTSAQPPDRMARFNDVARELQALLGRPDWSPGDKAQLVARLEGLLSTLAGPAQP 2090 Query 471 ASSGPSTTHDDEDITTATESQLFAILDDELGP 502 D+DI TATESQLFAILD+E+GP Sbjct 2091 PHPEDPDDPFDDDIATATESQLFAILDEEIGP 2122 >gi|254820901|ref|ZP_05225902.1| Pks7 [Mycobacterium intracellulare ATCC 13950] Length=1593 Score = 570 bits (1470), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 323/521 (62%), Positives = 381/521 (74%), Gaps = 27/521 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP R A MLAE+V L L LP +++DVR A AYR++SQARHVGKV LT+P Sbjct 1079 LEAGPDRTAAMLAEIVGLLTRGVLTPLPQRTFDVRCAAAAYRYVSQARHVGKVALTVPSG 1138 Query 61 -----------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALV 109 A G+V+ITGGTGMAGSA+ARHLV RYGV VVL SRAG VA LV Sbjct 1139 PGEVLSGCGGGLAGGSVVITGGTGMAGSALARHLVDRYGVAHVVLVSRAGAEAPGVAELV 1198 Query 110 DELGSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVD 166 D L AGA V V +CDVAD DAV +++ P L V HAAG+LDD +I+ LTP+RVD Sbjct 1199 DGLRRAGADVSVEACDVADPDAVGAMLSRIPAHYPLRGVVHAAGILDDGLISSLTPDRVD 1258 Query 167 KVLRAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSR 226 VLRAKVDGAWNLH+LTR LD+SAFV+FSSMAGIVG PGQANYAAAN+FLDGLAAYRR+ Sbjct 1259 AVLRAKVDGAWNLHQLTRDLDLSAFVVFSSMAGIVGTPGQANYAAANSFLDGLAAYRRAH 1318 Query 227 GLAALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVA 286 GLA LS+AWGLWEQASAMT HLG+RD+ RMSR+GLAPLPT QA+ DAA+L DRPV+VA Sbjct 1319 GLAGLSLAWGLWEQASAMTAHLGDRDKARMSRIGLAPLPTGQALAAFDAAMLVDRPVLVA 1378 Query 287 ARLDRAALAG--AELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHREL 342 A +DRAAL+ A LP L +L AGP RR++D GA S +GL++RL+GL+PE R REL Sbjct 1379 AAVDRAALSDNVAALPPLLRELAAGPARRVVDDTGA-AASSTGLSARLNGLSPEARQREL 1437 Query 343 TELVCSNAAIVLG-HSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYP 401 +LV NAA+VLG + +I+ +AFQ+LGFDSLTAVELRNRLK ATGLTL PTLIFDYP Sbjct 1438 IDLVRGNAAMVLGVPNPADINVGRAFQELGFDSLTAVELRNRLKNATGLTLSPTLIFDYP 1497 Query 402 TAAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQA 461 T LA HLD QLA A T QPN R N++TRELQALL P+WN DD++ L R+ Sbjct 1498 TPTVLAGHLDTQLAGAG--TDVQPNLMARVNDITRELQALLGAPDWNADDRSVLRARIHT 1555 Query 462 ILTDCT-APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 +L A PA S H D+D+ ATESQLFAILD+ELG Sbjct 1556 LLGAIAPADPADS----EHLDDDLDAATESQLFAILDEELG 1592 >gi|183982485|ref|YP_001850776.1| polyketide synthase Pks7 [Mycobacterium marinum M] gi|183175811|gb|ACC40921.1| polyketide synthase Pks7 [Mycobacterium marinum M] Length=2120 Score = 561 bits (1446), Expect = 9e-158, Method: Compositional matrix adjust. Identities = 318/519 (62%), Positives = 382/519 (74%), Gaps = 34/519 (6%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPD- 59 +EAGP IA+MLAEL L E L LP+K++DVR AR+AYRF+SQARH+GKVVLT+PD Sbjct 1617 IEAGPDLIARMLAELSRLLCAETLTPLPIKTFDVRLARQAYRFVSQARHIGKVVLTLPDE 1676 Query 60 -------AWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDEL 112 A A GTV+ITGGTGMAG+A+ARH+VSR+ V V+L SR+G E + L+ +L Sbjct 1677 TGAVPAGALAGGTVIITGGTGMAGTALARHVVSRHRVANVILVSRSGAQAEGTSELLGQL 1736 Query 113 GSAGARVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVDKVL 169 AGA VV+CDV+DRDAVA L+A P L V HAAGVLDD +I LTP+RVD VL Sbjct 1737 QDAGAEAAVVACDVSDRDAVAELLAQVPARYPLRGVIHAAGVLDDGLIASLTPQRVDTVL 1796 Query 170 RAKVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLA 229 RAK+DGAWNLHELTR L++SAFVLFSSMAGI+G GQ NYAAAN+FLDGLA +RR+ GL Sbjct 1797 RAKIDGAWNLHELTRGLNLSAFVLFSSMAGIIGTAGQGNYAAANSFLDGLAVHRRALGLP 1856 Query 230 ALSVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARL 289 +SVAWGLWEQASAMT HLGERD+ RMSRVGLA L T A+ DAA++ADR VVVA RL Sbjct 1857 GVSVAWGLWEQASAMTRHLGERDKARMSRVGLATLSTEHALELFDAAVVADRAVVVATRL 1916 Query 290 DRAALA--GAELPALFSQLVAGPIRRIIDGADE----VSGSGLASRLHGLTPEQRHRELT 343 D AL A LP L +L A P RR+I AD + +GL +RLHGL+ EQR REL Sbjct 1917 DANALKSNSAALPPLLGELAARPKRRVISDADAGDNIAAATGLVARLHGLSAEQRQRELV 1976 Query 344 ELVCSNAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPT 402 ++VCSNAA VLG S T +I+AH+AFQ+LGFDSLTAVELRNRLKTATGLTL PTLIFDYP+ Sbjct 1977 DVVCSNAATVLGRSSTADINAHRAFQELGFDSLTAVELRNRLKTATGLTLSPTLIFDYPS 2036 Query 403 AAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAI 462 A LAEHL I+LA A A QP+ RF+++ REL L+++P+W +DK +L RL I Sbjct 2037 PAALAEHLGIRLATATA----QPDLMRRFDDLARELDKLINRPDWTHEDKGKLSGRLHDI 2092 Query 463 LTDCTAPPASSGPSTTHDDEDITTATESQLFAILDDELG 501 L D +A D+DITTA+ESQLFAILD+ELG Sbjct 2093 LADLSA------------DDDITTASESQLFAILDEELG 2119 >gi|240170122|ref|ZP_04748781.1| polyketide synthase, Pks8 [Mycobacterium kansasii ATCC 12478] Length=1628 Score = 560 bits (1443), Expect = 2e-157, Method: Compositional matrix adjust. Identities = 309/515 (60%), Positives = 377/515 (74%), Gaps = 17/515 (3%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP IAQML+EL+EL L LPV+++DVR A++AYR++SQARHVGKVVLT+P Sbjct 1118 MEAGPDLIAQMLSELLELLSNRTLKPLPVRAFDVRCAQQAYRYVSQARHVGKVVLTIPQG 1177 Query 61 WAA------GTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 AA G+V+ITGGTGMAG+AVARHLV RYGV VVL SR GE VA LV +L Sbjct 1178 PAARSVLHGGSVVITGGTGMAGAAVARHLVDRYGVGHVVLVSRTGEQAPGVADLVAQLQQ 1237 Query 115 AGARVQVVSCDVADRDAVAGLVASQPD---LTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V V +CDVADRDA+ ++ PD L VFHAAGVLDDAVI LTP RV+ VL+A Sbjct 1238 GGAQVSVAACDVADRDALEAVLTELPDRFPLKGVFHAAGVLDDAVIASLTPSRVEAVLKA 1297 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLH+LT+ +D++AFV+FSSMAGI G PGQ +YAAANAFLDGLAAYRR RGL L Sbjct 1298 KVDGAWNLHQLTQDVDLTAFVMFSSMAGIAGDPGQGSYAAANAFLDGLAAYRRERGLPGL 1357 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDR 291 SVAWGLWEQ S MT HLGERD RM + GL L T A+ LD AL++DRPVVVAA+L+ Sbjct 1358 SVAWGLWEQPSTMTRHLGERDFARMKQAGLDRLTTEHALQLLDTALISDRPVVVAAQLNT 1417 Query 292 AAL-AGAELPALFSQLVAGPIRRIIDG-ADEVSGSGLASRLHGLTPEQRHRELTELVCSN 349 A + A AE+ L+ +LV P RR+ID S L SRL L+PEQRHREL +++ +N Sbjct 1418 AVMTANAEVLPLWRELVTRPSRRVIDSTGTAASMPDLISRLQSLSPEQRHRELVDVIITN 1477 Query 350 AAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAE 408 AA VLGH S +IDAHK FQDLGFDSLTAVELRNR+K ATG+TL PTLIFDYPT A LAE Sbjct 1478 AATVLGHSSAVDIDAHKPFQDLGFDSLTAVELRNRIKAATGMTLSPTLIFDYPTPAALAE 1537 Query 409 HLDIQL-ANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 HL QL + P + +QP+ RF++V REL L+++ +W ++K ++ +RL+A+L Sbjct 1538 HLAQQLDSTVPVLADEQPDRLARFDDVARELDTLVNRTDWTSEEKDQVSERLRAMLAGLA 1597 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELGP 502 P A + D DITTA+ES+LFAILD+ELGP Sbjct 1598 TPSA----AIVSQDADITTASESELFAILDEELGP 1628 >gi|289753751|ref|ZP_06513129.1| polyketide synthase [Mycobacterium tuberculosis EAS054] gi|289694338|gb|EFD61767.1| polyketide synthase [Mycobacterium tuberculosis EAS054] Length=635 Score = 560 bits (1442), Expect = 3e-157, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 134 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 193 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 194 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 253 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 254 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 313 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 314 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 373 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 374 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 433 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 434 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 493 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 494 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 553 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 554 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 608 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 609 --------SLTTEDDDIAAATESQLFAILDEELG 634 >gi|118462561|ref|YP_882292.1| erythronolide synthase, modules 3 and 4 [Mycobacterium avium 104] gi|118163848|gb|ABK64745.1| erythronolide synthase, modules 3 and 4 [Mycobacterium avium 104] Length=2128 Score = 558 bits (1439), Expect = 7e-157, Method: Compositional matrix adjust. Identities = 320/518 (62%), Positives = 377/518 (73%), Gaps = 18/518 (3%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGP RIA MLAE++ELF AL LPVK++D R A +AYRF+S ARH+GKVVLTMPD Sbjct 1613 MEAGPDRIAAMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARHIGKVVLTMPDG 1672 Query 61 WAA---GTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 A GT LITG TGMAG+A+ARHLV+R+ V ++L R GE +A L EL AGA Sbjct 1673 PAGLSGGTALITGATGMAGAALARHLVARHRVPHLMLVGRRGEAAPGMAELAAELRGAGA 1732 Query 118 RVQVVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVD 174 V V+SCDV DRDAVA ++A P L +VFHAAGVLDDAVI LTP R+D VLRAKVD Sbjct 1733 SVSVLSCDVGDRDAVAAMLAQVPARYPLRSVFHAAGVLDDAVIASLTPARIDTVLRAKVD 1792 Query 175 GAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVA 234 GAWNLHELT+ LD+SAFV+FSSMAGIVGAPGQ NYAAAN+FLD LA +R + GL ALSVA Sbjct 1793 GAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVA 1852 Query 235 WGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAAL 294 WG+WE+ SAMT HL ERD+ RMSR GL+ L T QA+ LD ALL ++P+VV RLDRAAL Sbjct 1853 WGMWEEPSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLDRAAL 1912 Query 295 AG--AELPALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAI 352 A A LP L S+L P RR+++ D VS +GL +RL G+ PEQR EL ELVC NAA Sbjct 1913 AQHRAALPPLLSELAGRPARRMLEHTDMVSLTGLRARLAGMNPEQRQAELVELVCGNAAA 1972 Query 353 VLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDI 412 VLGHS ++D AF DLGFDSLTAVELRNRLK ATGLTL PT+IFD+PT A LAEHL Sbjct 1973 VLGHSTADVDPGDAFSDLGFDSLTAVELRNRLKIATGLTLSPTVIFDHPTPAALAEHLGG 2032 Query 413 QLANA------PAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDC 466 QL +A PA T P+ S+R +EV ELQ LL QP +P D+ +L+ RLQ++L+ Sbjct 2033 QLTSAGPTPAAPAETAAPPDRSSRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLS-- 2090 Query 467 TAPPASSGPSTTHD--DEDITTATESQLFAILDDELGP 502 T P S P D D+DI TAT+SQLFAILDDE GP Sbjct 2091 TPPQPSGHPEFPEDAFDDDIATATDSQLFAILDDEAGP 2128 >gi|289757768|ref|ZP_06517146.1| polyketide synthase pks7 [Mycobacterium tuberculosis T85] gi|289713332|gb|EFD77344.1| polyketide synthase pks7 [Mycobacterium tuberculosis T85] Length=846 Score = 558 bits (1439), Expect = 7e-157, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 345 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 404 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 405 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 464 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 465 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 524 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 525 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 584 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 585 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 644 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 645 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 704 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 705 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 764 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 765 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 819 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 820 --------SLTTEDDDIAAATESQLFAILDEELG 845 >gi|308376784|ref|ZP_07668350.1| putative phosphopantetheine attachment site [Mycobacterium tuberculosis SUMu008] gi|308349972|gb|EFP38823.1| putative phosphopantetheine attachment site [Mycobacterium tuberculosis SUMu008] Length=952 Score = 557 bits (1436), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 451 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 510 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 511 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 570 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 571 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 630 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 631 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 690 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 691 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 750 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 751 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 810 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 811 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 870 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 871 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 925 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 926 --------SLTTEDDDIAAATESQLFAILDEELG 951 >gi|289447274|ref|ZP_06437018.1| polyketide synthase pks7 [Mycobacterium tuberculosis CPHL_A] gi|289420232|gb|EFD17433.1| polyketide synthase pks7 [Mycobacterium tuberculosis CPHL_A] Length=1814 Score = 553 bits (1425), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1313 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1372 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1373 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1432 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1433 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1492 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1493 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1552 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1553 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1612 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1613 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1672 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1673 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 1732 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 1733 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 1787 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 1788 --------SLTTEDDDIAAATESQLFAILDEELG 1813 >gi|308401191|ref|ZP_07493357.2| putative acyl transferase domain protein [Mycobacterium tuberculosis SUMu012] gi|308366102|gb|EFP54953.1| putative acyl transferase domain protein [Mycobacterium tuberculosis SUMu012] Length=1846 Score = 553 bits (1424), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1345 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1404 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1405 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1464 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1465 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1524 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1525 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1584 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1585 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1644 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1645 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1704 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1705 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 1764 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 1765 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 1819 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 1820 --------SLTTEDDDIAAATESQLFAILDEELG 1845 >gi|306788762|ref|ZP_07427084.1| polyketide synthase pks7 [Mycobacterium tuberculosis SUMu004] gi|306793096|ref|ZP_07431398.1| polyketide synthase pks7 [Mycobacterium tuberculosis SUMu005] gi|308334681|gb|EFP23532.1| polyketide synthase pks7 [Mycobacterium tuberculosis SUMu004] gi|308338474|gb|EFP27325.1| polyketide synthase pks7 [Mycobacterium tuberculosis SUMu005] Length=2126 Score = 553 bits (1424), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|340626667|ref|YP_004745119.1| putative polyketide synthase PKS7 [Mycobacterium canettii CIPT 140010059] gi|340004857|emb|CCC44002.1| putative polyketide synthase PKS7 [Mycobacterium canettii CIPT 140010059] Length=2126 Score = 553 bits (1424), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|289745901|ref|ZP_06505279.1| polyketide synthase pks7 [Mycobacterium tuberculosis 02_1987] gi|294996612|ref|ZP_06802303.1| polyketide synthase pks7 [Mycobacterium tuberculosis 210] gi|289686429|gb|EFD53917.1| polyketide synthase pks7 [Mycobacterium tuberculosis 02_1987] gi|326903275|gb|EGE50208.1| polyketide synthase pks7 [Mycobacterium tuberculosis W-148] gi|339294619|gb|AEJ46730.1| polyketide synthase pks7 [Mycobacterium tuberculosis CCDC5079] gi|339298252|gb|AEJ50362.1| polyketide synthase pks7 [Mycobacterium tuberculosis CCDC5180] Length=2126 Score = 553 bits (1424), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|15608799|ref|NP_216177.1| polyketide synthase pks7 [Mycobacterium tuberculosis H37Rv] gi|15841117|ref|NP_336154.1| polyketide synthase [Mycobacterium tuberculosis CDC1551] gi|148661457|ref|YP_001282980.1| putative polyketide synthase Pks7 [Mycobacterium tuberculosis H37Ra] 27 more sequence titles Length=2126 Score = 553 bits (1424), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|298525160|ref|ZP_07012569.1| polyketide synthase pks7 [Mycobacterium tuberculosis 94_M4241A] gi|298494954|gb|EFI30248.1| polyketide synthase pks7 [Mycobacterium tuberculosis 94_M4241A] Length=2126 Score = 552 bits (1423), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|289574330|ref|ZP_06454557.1| polyketide synthase pks7 [Mycobacterium tuberculosis K85] gi|289538761|gb|EFD43339.1| polyketide synthase pks7 [Mycobacterium tuberculosis K85] Length=2126 Score = 552 bits (1423), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|31792848|ref|NP_855341.1| polyketide synthase pks7 [Mycobacterium bovis AF2122/97] gi|121637569|ref|YP_977792.1| putative polyketide synthase pks7 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990044|ref|YP_002644731.1| putative polyketide synthase [Mycobacterium bovis BCG str. Tokyo 172] gi|31618438|emb|CAD96356.1| Probable polyketide synthase pks7 [Mycobacterium bovis AF2122/97] gi|121493216|emb|CAL71687.1| Probable polyketide synthase pks7 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773157|dbj|BAH25963.1| putative polyketide synthase [Mycobacterium bovis BCG str. Tokyo 172] gi|341601587|emb|CCC64260.1| probable polyketide synthase pks7 [Mycobacterium bovis BCG str. Moreau RDJ] Length=2126 Score = 552 bits (1423), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 384/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+SQARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSQARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|254231859|ref|ZP_04925186.1| polyketide synthase pks7 [Mycobacterium tuberculosis C] gi|124600918|gb|EAY59928.1| polyketide synthase pks7 [Mycobacterium tuberculosis C] Length=2126 Score = 550 bits (1416), Expect = 3e-154, Method: Compositional matrix adjust. Identities = 340/514 (67%), Positives = 383/514 (75%), Gaps = 26/514 (5%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 +EAGP RIA ML+E+V L L RLPVK++D R A AYRF+S ARH+GKVVLT+PD Sbjct 1625 VEAGPDRIAAMLSEVVGLLAAGVLARLPVKTFDARCAPAAYRFVSLARHIGKVVLTIPDG 1684 Query 61 ------WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGS 114 A GTV++TGGTGMAGSAVA HLV R+GV +VL SR+GE + A + L Sbjct 1685 PGGQSGLAGGTVVVTGGTGMAGSAVATHLVRRHGVANLVLVSRSGEQADRAAEVAALLRE 1744 Query 115 AGARVQVVSCDVADRDAVAGLVAS---QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRA 171 GA+V VVSCDVADRDA+A L+A + L VFHAAGVLDDAVITGLTP+RVD VLRA Sbjct 1745 GGAQVAVVSCDVADRDALAALLAGLDPRYPLKGVFHAAGVLDDAVITGLTPDRVDTVLRA 1804 Query 172 KVDGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAL 231 KVDGAWNLHELT +D+SAFV+FSSMAGIVG P Q NYAAANAFLDGL AYRRSRGLA L Sbjct 1805 KVDGAWNLHELTEDMDLSAFVVFSSMAGIVGTPAQGNYAAANAFLDGLVAYRRSRGLAGL 1864 Query 232 SVAWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVV--AARL 289 SVAWGLWEQASAMT HLGERDR RM++ GLAPL T QA+GFLD AL ADR VVV Sbjct 1865 SVAWGLWEQASAMTRHLGERDRARMTQAGLAPLTTEQALGFLDTALQADRAVVVAARLDR 1924 Query 290 DRAALAGAELPALFSQLVAGPIRRIIDGADE-VSGSGLASRLHGLTPEQRHRELTELVCS 348 A AGA LPALFSQL AGP RR ID AD VS SGL SRLH LTPE+R RELT+LV S Sbjct 1925 AALAGAGAALPALFSQLAAGPTRRRIDAADTAVSMSGLVSRLHALTPERRQRELTDLVIS 1984 Query 349 NAAIVLGHSGT-EIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELA 407 NAA VLG S + +I+AHKAFQDLGFDSLTAVELRNRLKTATGLTL PTLIFDYPT A LA Sbjct 1985 NAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPATLA 2044 Query 408 EHLDIQLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCT 467 EHLD +L A DQ + S R +++TREL LLDQP+ + + K L RLQ +LT Sbjct 2045 EHLDSRLVTASG--SDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLT--- 2099 Query 468 APPASSGPSTTHDDEDITTATESQLFAILDDELG 501 S T +D+DI ATESQLFAILD+ELG Sbjct 2100 --------SLTTEDDDIAAATESQLFAILDEELG 2125 >gi|254550672|ref|ZP_05141119.1| polyketide synthase pks17 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=259 Score = 524 bits (1349), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 259/259 (100%), Positives = 259/259 (100%), Gaps = 0/259 (0%) Query 244 MTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELPALF 303 MTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELPALF Sbjct 1 MTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALAGAELPALF 60 Query 304 SQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTEIDA 363 SQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTEIDA Sbjct 61 SQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSNAAIVLGHSGTEIDA 120 Query 364 HKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAVTVD 423 HKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAVTVD Sbjct 121 HKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAVTVD 180 Query 424 QPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHDDED 483 QPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHDDED Sbjct 181 QPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHDDED 240 Query 484 ITTATESQLFAILDDELGP 502 ITTATESQLFAILDDELGP Sbjct 241 ITTATESQLFAILDDELGP 259 >gi|254550671|ref|ZP_05141118.1| polyketide synthase pks17 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=295 Score = 493 bits (1268), Expect = 5e-137, Method: Compositional matrix adjust. Identities = 250/256 (98%), Positives = 250/256 (98%), Gaps = 0/256 (0%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA Sbjct 9 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 68 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ Sbjct 69 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 128 Query 121 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 180 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH Sbjct 129 VVSCDVADRDAVAGLVASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAWNLH 188 Query 181 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGLWEQ 240 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAA WGL EQ Sbjct 189 ELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAAFLEEWGLCEQ 248 Query 241 ASAMTEHLGERDRVRM 256 ASAMTEHL ERDRVRM Sbjct 249 ASAMTEHLSERDRVRM 264 >gi|183980137|ref|YP_001848428.1| polyketide synthase PKS [Mycobacterium marinum M] gi|183173463|gb|ACC38573.1| polyketide synthase PKS [Mycobacterium marinum M] Length=2197 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 257/427 (61%), Positives = 308/427 (73%), Gaps = 13/427 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 E PQR+ QMLAEL+ LF LHRLPVK+WDVR A +AY+F+SQARH+GKVVL+ P Sbjct 1670 EVAPQRLGQMLAELMTLFAAGKLHRLPVKTWDVRCAPQAYQFVSQARHIGKVVLSAPTEL 1729 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 DA AAGTVLITGGTG+ GS +ARHLVS YGVR +VL SR GE VA LVDEL AGA Sbjct 1730 RDALAAGTVLITGGTGLVGSVLARHLVSAYGVRNLVLVSRMGEQGAGVAELVDELSDAGA 1789 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 RV V +CDVAD+ AV L+A P LT V HAAGVLDDAVIT +TP++VD VLRAKV Sbjct 1790 RVLVAACDVADQSAVEKLIAGWGREYPALTGVIHAAGVLDDAVITSMTPDQVDSVLRAKV 1849 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 DGAWNLH TR L +S FVL SS+AG+VGAPGQ NYAAANAFLD L RR+ GLA +S+ Sbjct 1850 DGAWNLHHATRGLGLSMFVLCSSIAGVVGAPGQGNYAAANAFLDALVTDRRAHGLAGVSL 1909 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 WGLWEQAS MT+HL D R+SR G A + QA+ DAAL+ D+P V+AARLDR A Sbjct 1910 GWGLWEQASGMTKHLRGSDVSRLSRGGFAAISAQQALDLFDAALIVDQPTVLAARLDRRA 1969 Query 294 LA----GAELPALFSQLVAGPIRRIIDGADEVSGSGLASRLHGLTPEQRHRELTELVCSN 349 L A+LP LFS L+ P+RR +D + L +RL+ + P+++H LTE+VC+ Sbjct 1970 LENPALNADLPTLFSDLITRPMRRNVDNDGTPTELALVNRLNMMNPDEQHDLLTEVVCTQ 2029 Query 350 AAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAE 408 A +VLG + +ID + F DLGFDSLTA+ELRNRLKT TGLTLPPTLIFD+ + LA+ Sbjct 2030 AVMVLGRLNAADIDPNATFSDLGFDSLTAIELRNRLKTVTGLTLPPTLIFDHRAPSALAQ 2089 Query 409 HLDIQLA 415 HL QL Sbjct 2090 HLGQQLC 2096 >gi|240171787|ref|ZP_04750446.1| putative polyketide synthase [Mycobacterium kansasii ATCC 12478] Length=2118 Score = 465 bits (1196), Expect = 1e-128, Method: Compositional matrix adjust. Identities = 266/429 (63%), Positives = 306/429 (72%), Gaps = 17/429 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ ML E+ ELF T+ LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1665 EAGPVRMQAMLREVKELFDTQVLHRLPVSTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1724 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTVLITG TGM G+ +ARHLVS Y VR VVLASR G+ A L EL AGA Sbjct 1725 ADGLADGTVLITGATGMVGAVLARHLVSAYRVRHVVLASRRGDRAAGAAELAAELADAGA 1784 Query 118 RVQVVSCDVADRDAVAGLV----ASQPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 RVQVV+CDVADRDAVAGL A P + V HAAGV+DDAVI+ LTP+R+D VLRAKV Sbjct 1785 RVQVVACDVADRDAVAGLFTQLAAEWPPVRGVIHAAGVVDDAVISSLTPDRIDTVLRAKV 1844 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLHE TR LD+S FVL SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA S+ Sbjct 1845 DAAWNLHEATRGLDLSMFVLCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGTSL 1904 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ SA+T HL ERD RMSR GL + QA+ DAAL D PV+VA RLDRAA Sbjct 1905 AWGLWEQTSAITAHLSERDLARMSRSGLVAMSPEQALELFDAALTIDHPVMVATRLDRAA 1964 Query 294 L-----AGAELPALFSQLVAGPIRRIIDGADEV--SGSGLASRLHGLTPEQRHRELTELV 346 L AG LPALFS L P RR ID + S S LA RLHGL PE++H L +V Sbjct 1965 LNARAQAGG-LPALFSGLARRPRRRQIDDTADATQSKSALAQRLHGLAPEEQHGLLVGIV 2023 Query 347 CSNAAIVLGHSGTE-IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 + AA VLG E ID FQDLGFDSLTAVELRNRLK ATGLTLPPT+I D+PT Sbjct 2024 RAQAAAVLGRPAPEDIDPDSGFQDLGFDSLTAVELRNRLKNATGLTLPPTVILDHPTPTA 2083 Query 406 LAEHLDIQL 414 +A+++ Q+ Sbjct 2084 VADYIARQI 2092 >gi|254552020|ref|ZP_05142467.1| polyketide synthase pks1 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=909 Score = 464 bits (1193), Expect = 2e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 455 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 514 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 515 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 574 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 575 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 634 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 635 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 694 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 695 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 754 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 755 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 813 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 814 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 873 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 874 VAEYVAQQMSGS 885 >gi|289444505|ref|ZP_06434249.1| probable polyketide synthase pks1 [Mycobacterium tuberculosis T46] gi|289759070|ref|ZP_06518448.1| polyketide synthase 7 [Mycobacterium tuberculosis T85] gi|289417424|gb|EFD14664.1| probable polyketide synthase pks1 [Mycobacterium tuberculosis T46] gi|289714634|gb|EFD78646.1| polyketide synthase 7 [Mycobacterium tuberculosis T85] Length=612 Score = 464 bits (1193), Expect = 2e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 158 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 217 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 218 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 277 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 278 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 337 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 338 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 397 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 398 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 457 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 458 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 516 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 517 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 576 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 577 VAEYVAQQMSGS 588 >gi|289448613|ref|ZP_06438357.1| polyketide synthase PKS1 [Mycobacterium tuberculosis CPHL_A] gi|289421571|gb|EFD18772.1| polyketide synthase PKS1 [Mycobacterium tuberculosis CPHL_A] Length=736 Score = 463 bits (1192), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 282 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 341 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 342 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 401 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 402 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 461 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 462 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 521 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 522 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 581 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 582 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 640 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 641 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 700 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 701 VAEYVAQQMSGS 712 >gi|340627935|ref|YP_004746387.1| putative polyketide synthase PKS1 [Mycobacterium canettii CIPT 140010059] gi|340006125|emb|CCC45297.1| putative polyketide synthase PKS1 [Mycobacterium canettii CIPT 140010059] Length=1616 Score = 463 bits (1191), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 305/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T+ LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1162 EAGPARMQEMLAEVRELFDTQELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1221 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1222 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1281 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1282 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1341 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1342 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1401 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1402 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1461 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1462 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 1520 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 1521 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 1580 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 1581 VAEYVAQQMSGS 1592 >gi|294993968|ref|ZP_06799659.1| putative polyketide synthase [Mycobacterium tuberculosis 210] gi|326904561|gb|EGE51494.1| polyketide synthase pks1 [Mycobacterium tuberculosis W-148] Length=2107 Score = 462 bits (1190), Expect = 4e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1653 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1712 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1713 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1772 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1773 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1832 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1833 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1892 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1893 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1952 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1953 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 2011 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 2012 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 2071 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 2072 VAEYVAQQMSGS 2083 >gi|240170497|ref|ZP_04749156.1| polyketide synthase, Pks12 [Mycobacterium kansasii ATCC 12478] Length=1565 Score = 462 bits (1190), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 252/427 (60%), Positives = 309/427 (73%), Gaps = 10/427 (2%) Query 1 MEAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMPDA 60 EAGP RIAQ+LAEL LF E L LPV ++DVR A A R+LSQARHVGKVV++MPDA Sbjct 1061 FEAGPDRIAQILAELAALFDDEVLRPLPVTTFDVRRAPAALRYLSQARHVGKVVMSMPDA 1120 Query 61 WAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGARVQ 120 WAAGTVLITGGTGMAGSA+ARH+V+R+GVRQ+VL SR G LV EL +AGA+V Sbjct 1121 WAAGTVLITGGTGMAGSALARHVVTRHGVRQLVLVSRRGPDAPGAEELVAELDAAGAQVH 1180 Query 121 VVSCDVADRDAVAGLVASQP---DLTAVFHAAGVLDDAVITGLTPERVDKVLRAKVDGAW 177 VV+CD ADR A+A ++A P L+AV H AG LDDAV+T LTPER++ VLRAKVD AW Sbjct 1181 VVACDAADRAALAKVIADIPVQQPLSAVIHTAGALDDAVVTSLTPERMETVLRAKVDAAW 1240 Query 178 NLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSVAWGL 237 NLHELT LDVSAFV+FSSMAG+VG+ GQANYAAAN+FLDGLA +RR+RGL A+S+ WGL Sbjct 1241 NLHELTCDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDGLAVHRRARGLPAISLGWGL 1300 Query 238 WEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAALA-- 295 W QASAMT L D R +R G+ + + +A+G LD A++ D P ++ A +D AAL Sbjct 1301 WNQASAMTGGLASVDFKRFARDGVVAMSSEEALGLLDTAMIVDEPFMLPAHIDFAALRVK 1360 Query 296 --GAELPALFSQLVAGPIRRIIDG--ADEVSGSGLASRLHGLTPEQRHRELTELVCSNAA 351 LP +F L+ P RR +D A S S L RL GL +++H L +LV SN A Sbjct 1361 FDNGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLDGLPDDEQHAILLDLVRSNIA 1420 Query 352 IVLGHSGTE-IDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHL 410 VLG++ E ID +AFQ+LGFDSLTAVE+RNRLK+ATGL L PTLIFDYP +A LA ++ Sbjct 1421 TVLGNTSPEAIDPDRAFQELGFDSLTAVEMRNRLKSATGLALSPTLIFDYPNSAALAGYM 1480 Query 411 DIQLANA 417 +L A Sbjct 1481 HRELLGA 1487 >gi|289575652|ref|ZP_06455879.1| polyketide synthase pks1 [Mycobacterium tuberculosis K85] gi|339632954|ref|YP_004724596.1| polyketide synthase [Mycobacterium africanum GM041182] gi|289540083|gb|EFD44661.1| polyketide synthase pks1 [Mycobacterium tuberculosis K85] gi|339332310|emb|CCC28022.1| putative polyketide synthase [Mycobacterium africanum GM041182] Length=2112 Score = 462 bits (1190), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1658 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1717 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1718 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1777 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1778 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1837 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1838 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1897 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1898 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1957 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1958 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 2016 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 2017 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 2076 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 2077 VAEYVAQQMSGS 2088 >gi|289746746|ref|ZP_06506124.1| polyketide synthase PKS1 [Mycobacterium tuberculosis 02_1987] gi|298526415|ref|ZP_07013824.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|289687274|gb|EFD54762.1| polyketide synthase PKS1 [Mycobacterium tuberculosis 02_1987] gi|298496209|gb|EFI31503.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=2114 Score = 462 bits (1190), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1660 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1719 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1720 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1779 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1780 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1839 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1840 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1899 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1900 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1959 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1960 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 2018 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 2019 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 2078 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 2079 VAEYVAQQMSGS 2090 >gi|339295785|gb|AEJ47896.1| polyketide synthase PKS1 [Mycobacterium tuberculosis CCDC5079] Length=1982 Score = 462 bits (1189), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1528 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1587 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1588 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1647 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1648 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1707 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1708 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1767 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1768 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1827 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1828 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 1886 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 1887 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 1946 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 1947 VAEYVAQQMSGS 1958 >gi|167970038|ref|ZP_02552315.1| putative polyketide synthase pks1 [Mycobacterium tuberculosis H37Ra] gi|313659897|ref|ZP_07816777.1| polyketide synthase pks1 [Mycobacterium tuberculosis KZN V2475] Length=1619 Score = 462 bits (1189), Expect = 6e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1165 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1224 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1225 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1284 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1285 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1344 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1345 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1404 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1405 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1464 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1465 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 1523 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 1524 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 1583 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 1584 VAEYVAQQMSGS 1595 >gi|289755061|ref|ZP_06514439.1| polyketide synthase pks1 [Mycobacterium tuberculosis EAS054] gi|289695648|gb|EFD63077.1| polyketide synthase pks1 [Mycobacterium tuberculosis EAS054] Length=1482 Score = 462 bits (1189), Expect = 6e-128, Method: Compositional matrix adjust. Identities = 260/432 (61%), Positives = 304/432 (71%), Gaps = 17/432 (3%) Query 2 EAGPQRIAQMLAELVELFKTEALHRLPVKSWDVRHAREAYRFLSQARHVGKVVLTMP--- 58 EAGP R+ +MLAE+ ELF T LHRLPV +WDVR A A+RF+SQARH+GKVVLTMP Sbjct 1028 EAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSAL 1087 Query 59 -DAWAAGTVLITGGTGMAGSAVARHLVSRYGVRQVVLASRAGEHTESVAALVDELGSAGA 117 D A GTV+ITG TG G +ARHLV YGVR +VLASR G+ E A L +L AGA Sbjct 1088 ADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGA 1147 Query 118 RVQVVSCDVADRDAVAGLVAS----QPDLTAVFHAAGVLDDAVITGLTPERVDKVLRAKV 173 +VQVV+CDVADR AVAGL A P + V HAAGVLDDAVIT LTP+R+D VLRAKV Sbjct 1148 KVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKV 1207 Query 174 DGAWNLHELTRHLDVSAFVLFSSMAGIVGAPGQANYAAANAFLDGLAAYRRSRGLAALSV 233 D AWNLH+ T LD+S F L SS+A VG+PGQ NY+AANAFLDGLAA+R++ GLA +S+ Sbjct 1208 DAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISL 1267 Query 234 AWGLWEQASAMTEHLGERDRVRMSRVGLAPLPTNQAMGFLDAALLADRPVVVAARLDRAA 293 AWGLWEQ MT HL RD RMSR GLAP+ +A+ DAAL D P+ VA LDRAA Sbjct 1268 AWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAA 1327 Query 294 L-----AGAELPALFSQLVAGPIRRIID--GADEVSGSGLASRLHGLTPEQRHRELTELV 346 L AGA LPALFS L P RR ID G S S LA RLHGL +++ L LV Sbjct 1328 LDARAQAGA-LPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLV 1386 Query 347 CSNAAIVLGH-SGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAE 405 C AA VLG S ++D F DLGFDSLTAVELRNRLKTATGLTLPPT+IFD+PT Sbjct 1387 CLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTA 1446 Query 406 LAEHLDIQLANA 417 +AE++ Q++ + Sbjct 1447 VAEYVAQQMSGS 1458 Lambda K H 0.318 0.132 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1083597119368 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40