BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1666c Length=430 Score E Sequences producing significant alignments: (Bits) Value gi|15841122|ref|NP_336159.1| P450 heme-thiolate protein [Mycobac... 868 0.0 gi|15608804|ref|NP_216182.1| cytochrome P450 139 CYP139 [Mycobac... 866 0.0 gi|289443124|ref|ZP_06432868.1| probable cytochrome P450 139 CYP... 785 0.0 gi|289745896|ref|ZP_06505274.1| cytochrome P450 139 cyp139 [Myco... 707 0.0 gi|183982489|ref|YP_001850780.1| cytochrome P450 139A3 Cyp139A3 ... 680 0.0 gi|240170125|ref|ZP_04748784.1| cytochrome P450 139A3 Cyp139A3 [... 647 0.0 gi|118464338|ref|YP_882289.1| P450 heme-thiolate protein [Mycoba... 630 2e-178 gi|254775551|ref|ZP_05217067.1| P450 heme-thiolate protein [Myco... 627 1e-177 gi|41407471|ref|NP_960307.1| hypothetical protein MAP1373c [Myco... 624 1e-176 gi|254550675|ref|ZP_05141122.1| cytochrome P450 139 cyp139 [Myco... 542 3e-152 gi|333989273|ref|YP_004521887.1| cytochrome P450 [Mycobacterium ... 514 9e-144 gi|257055961|ref|YP_003133793.1| cytochrome P450 [Saccharomonosp... 476 3e-132 gi|336457825|gb|EGO36819.1| cytochrome P450 [Mycobacterium avium... 450 2e-124 gi|254550676|ref|ZP_05141123.1| P450 heme-thiolate protein [Myco... 251 2e-64 gi|284042314|ref|YP_003392654.1| cytochrome P450 [Conexibacter w... 200 4e-49 gi|229119397|ref|ZP_04248697.1| Cytochrome P450 hydroxylase [Bac... 190 4e-46 gi|254409384|ref|ZP_05023165.1| Cytochrome P450 superfamily [Mic... 179 1e-42 gi|315647692|ref|ZP_07900793.1| cytochrome P450 [Paenibacillus v... 178 2e-42 gi|298242977|ref|ZP_06966784.1| cytochrome P450 [Ktedonobacter r... 177 2e-42 gi|119485435|ref|ZP_01619763.1| cytochrome P450 [Lyngbya sp. PCC... 176 6e-42 gi|190333631|gb|ACE73823.1| putative cytochrome P450 [Streptomyc... 174 2e-41 gi|297625126|ref|YP_003706560.1| cytochrome P450 [Truepera radio... 174 4e-41 gi|159901767|ref|YP_001548012.1| cytochrome P450 [Herpetosiphon ... 173 5e-41 gi|288963095|ref|YP_003453374.1| cytochrome P450 [Azospirillum s... 172 1e-40 gi|339010031|ref|ZP_08642602.1| cytochrome P450 [Brevibacillus l... 172 1e-40 gi|345013216|ref|YP_004815570.1| cytochrome P450 [Streptomyces v... 171 2e-40 gi|298250768|ref|ZP_06974572.1| cytochrome P450 [Ktedonobacter r... 171 2e-40 gi|260653871|dbj|BAI44339.1| P450 [Streptomyces melanosporofaciens] 171 3e-40 gi|325517539|gb|ADZ25011.1| cytochrome P450 hydroxylase [Sorangi... 171 3e-40 gi|225874539|ref|YP_002755998.1| cytochrome P450 family protein ... 170 4e-40 gi|294628911|ref|ZP_06707471.1| cytochrome P450 family protein [... 170 5e-40 gi|190333627|gb|ACE73821.1| putative cytochrome P450 [Streptomyc... 170 5e-40 gi|239991999|ref|ZP_04712663.1| putative cytochrome P450 [Strept... 169 6e-40 gi|297156019|gb|ADI05731.1| cytochrome P450 family protein [Stre... 169 1e-39 gi|313116936|ref|YP_004038060.1| cytochrome P450 [Halogeometricu... 169 1e-39 gi|218245968|ref|YP_002371339.1| cytochrome P450 [Cyanothece sp.... 168 2e-39 gi|158341212|ref|YP_001522424.1| cytochrome P450 family protein ... 167 3e-39 gi|298250363|ref|ZP_06974167.1| cytochrome P450 [Ktedonobacter r... 167 4e-39 gi|257059251|ref|YP_003137139.1| cytochrome P450 [Cyanothece sp.... 167 4e-39 gi|288554506|ref|YP_003426441.1| cytochrome P450, hydroxylase or... 166 7e-39 gi|291566629|dbj|BAI88901.1| cytochrome P450 [Arthrospira platen... 165 1e-38 gi|284051209|ref|ZP_06381419.1| cytochrome P450 [Arthrospira pla... 165 1e-38 gi|254416793|ref|ZP_05030542.1| Cytochrome P450 superfamily [Mic... 164 2e-38 gi|337749462|ref|YP_004643624.1| cytochrome P450 hydroxylase [Pa... 164 2e-38 gi|162453161|ref|YP_001615528.1| cytochrome P450 CYP263A1 [Soran... 164 3e-38 gi|338739348|ref|YP_004676310.1| Cytochrome P450 family protein ... 164 4e-38 gi|294628910|ref|ZP_06707470.1| cytochrome P450 family protein [... 163 4e-38 gi|113477166|ref|YP_723227.1| cytochrome P450 [Trichodesmium ery... 163 5e-38 gi|322371142|ref|ZP_08045694.1| cytochrome P450 [Haladaptatus pa... 162 7e-38 gi|298250792|ref|ZP_06974596.1| cytochrome P450 [Ktedonobacter r... 162 9e-38 >gi|15841122|ref|NP_336159.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|254231862|ref|ZP_04925189.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis C] gi|254364510|ref|ZP_04980556.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis str. Haarlem] 26 more sequence titles Length=436 Score = 868 bits (2242), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/430 (100%), Positives = 430/430 (100%), Gaps = 0/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV Sbjct 7 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 66 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL Sbjct 67 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 126 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR Sbjct 127 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 186 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS Sbjct 187 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 246 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI Sbjct 247 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 306 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH Sbjct 307 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 366 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT Sbjct 367 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 426 Query 421 VEIRKSAPAQ 430 VEIRKSAPAQ Sbjct 427 VEIRKSAPAQ 436 >gi|15608804|ref|NP_216182.1| cytochrome P450 139 CYP139 [Mycobacterium tuberculosis H37Rv] gi|31792853|ref|NP_855346.1| cytochrome P450 139 CYP139 [Mycobacterium bovis AF2122/97] gi|121637574|ref|YP_977797.1| putative cytochrome P450 139 CYP139 [Mycobacterium bovis BCG str. Pasteur 1173P2] 49 more sequence titles Length=430 Score = 866 bits (2238), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/430 (99%), Positives = 430/430 (100%), Gaps = 0/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV Sbjct 1 MRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL Sbjct 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR Sbjct 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS Sbjct 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI Sbjct 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH Sbjct 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT Sbjct 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 Query 421 VEIRKSAPAQ 430 VEIRKSAPAQ Sbjct 421 VEIRKSAPAQ 430 >gi|289443124|ref|ZP_06432868.1| probable cytochrome P450 139 CYP139 [Mycobacterium tuberculosis T46] gi|294996617|ref|ZP_06802308.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis 210] gi|289416043|gb|EFD13283.1| probable cytochrome P450 139 CYP139 [Mycobacterium tuberculosis T46] Length=390 Score = 785 bits (2027), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/390 (99%), Positives = 390/390 (100%), Gaps = 0/390 (0%) Query 41 VFANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSN 100 +FANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSN Sbjct 1 MFANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSN 60 Query 101 IDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQ 160 IDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQ Sbjct 61 IDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQ 120 Query 161 VMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLS 220 VMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLS Sbjct 121 VMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLS 180 Query 221 DNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSA 280 DNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSA Sbjct 181 DNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSA 240 Query 281 LTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPT 340 LTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPT Sbjct 241 LTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPT 300 Query 341 EFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQ 400 EFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQ Sbjct 301 EFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQ 360 Query 401 RTHRIRAANFAALRPWPGLTVEIRKSAPAQ 430 RTHRIRAANFAALRPWPGLTVEIRKSAPAQ Sbjct 361 RTHRIRAANFAALRPWPGLTVEIRKSAPAQ 390 >gi|289745896|ref|ZP_06505274.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis 02_1987] gi|289686424|gb|EFD53912.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis 02_1987] Length=351 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/351 (99%), Positives = 351/351 (100%), Gaps = 0/351 (0%) Query 80 VVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAV 139 +VAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAV Sbjct 1 MVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAV 60 Query 140 HSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPR 199 HSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPR Sbjct 61 HSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPR 120 Query 200 PDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWES 259 PDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWES Sbjct 121 PDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWES 180 Query 260 AASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAG 319 AASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAG Sbjct 181 AASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAG 240 Query 320 RLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMAT 379 RLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMAT Sbjct 241 RLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMAT 300 Query 380 TEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIRKSAPAQ 430 TEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIRKSAPAQ Sbjct 301 TEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIRKSAPAQ 351 >gi|183982489|ref|YP_001850780.1| cytochrome P450 139A3 Cyp139A3 [Mycobacterium marinum M] gi|183175815|gb|ACC40925.1| cytochrome P450 139A3 Cyp139A3 [Mycobacterium marinum M] Length=433 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/430 (80%), Positives = 368/430 (86%), Gaps = 3/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 V Y GEALLALYR RG I+AGVG HG+ YLLG EANRFVFANADAFSW +TFESLVPV Sbjct 7 VPYRPGEALLALYRRRGAFIDAGVGRHGFVYLLGPEANRFVFANADAFSWRETFESLVPV 66 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRS+VAPGLRH VQ YVATMVS ID VID W+PGQ LDIYQE Sbjct 67 DGPTALIVSDGEDHRRRRSIVAPGLRHRSVQDYVATMVSTIDNVIDSWRPGQPLDIYQEF 126 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 R AVRRST ESLFG RLA HSD+LG QLQPL+DLT R PQVM+LQQR+NSPGWRRAMAAR Sbjct 127 RCAVRRSTTESLFGPRLASHSDYLGRQLQPLIDLTHRLPQVMQLQQRLNSPGWRRAMAAR 186 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 RID+LIDA+IA+AR P PDD MLT LI+G SEEG LSDNEIRDSIVSLI AGYETTS Sbjct 187 TRIDELIDAEIANARAEPSPDDRMLTALINGRSEEGCALSDNEIRDSIVSLIAAGYETTS 246 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWA Y+LLT+PG WE+AA EVARVLGG P+A+ L ALTYLNGVVHETLRLYSPGV+ Sbjct 247 GALAWATYSLLTLPGAWETAAREVARVLGGTAPSAETLGALTYLNGVVHETLRLYSPGVV 306 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARR++RDLWFDGHRI +GRLLIFSAYVTHR+PE+WP PT+F P RWDP A DYRKPAPH Sbjct 307 SARRLIRDLWFDGHRINSGRLLIFSAYVTHRIPEVWPNPTQFLPQRWDPAAPDYRKPAPH 366 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFSGGLHRCIGAVMATTE+ V+LARLVAR L+LPAQ RIRAANFAAL P PGL Sbjct 367 EFIPFSGGLHRCIGAVMATTELVVLLARLVARTRLRLPAQ---RIRAANFAALAPKPGLR 423 Query 421 VEIRKSAPAQ 430 VE S PAQ Sbjct 424 VEFVDSVPAQ 433 >gi|240170125|ref|ZP_04748784.1| cytochrome P450 139A3 Cyp139A3 [Mycobacterium kansasii ATCC 12478] Length=426 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/430 (79%), Positives = 366/430 (86%), Gaps = 10/430 (2%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 V Y GEALLALYR RG +I+AGVG HG+ YLLGAEAN+FVFANADAFSW +TFESLVPV Sbjct 7 VPYLPGEALLALYRHRGAVIDAGVGRHGFVYLLGAEANKFVFANADAFSWRETFESLVPV 66 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRSVVAPGL H VQ YV TMVS ID VID W+PGQRLD+YQE Sbjct 67 DGPTALIVSDGEDHRRRRSVVAPGLHHRRVQDYVQTMVSTIDAVIDAWRPGQRLDLYQEF 126 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 RSAVRRSTAESLFG RLA HSDFLGEQLQPLLDLT RPPQ+MRLQ+R+NSPGWR AMAAR Sbjct 127 RSAVRRSTAESLFGPRLAAHSDFLGEQLQPLLDLTHRPPQLMRLQRRLNSPGWRSAMAAR 186 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 RIDDL++ I+DAR P PDDHMLT LI TLSDNE+RD+IVSLITAGYETTS Sbjct 187 HRIDDLVNTVISDARARPMPDDHMLTALID-------TLSDNEVRDAIVSLITAGYETTS 239 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWA +ALLT+PG WE+ A EV RVLGG PAAD++ +LT+LNG+V ETLRLYSPGVI Sbjct 240 GALAWAAHALLTLPGAWETVAREVDRVLGGNAPAADNIDSLTFLNGLVQETLRLYSPGVI 299 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRV+RDL FDGHRIR+GRLLIFSAYVTHRLPEIWP P EFRP RWDP++ DYR+PAPH Sbjct 300 SARRVMRDLVFDGHRIRSGRLLIFSAYVTHRLPEIWPAPREFRPQRWDPDSPDYRRPAPH 359 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFSGGLHRCIGAVMATTEM V+LARLVAR L+LPAQ RIRAANFAAL P PGL Sbjct 360 EFIPFSGGLHRCIGAVMATTEMMVMLARLVARTTLRLPAQ---RIRAANFAALSPKPGLI 416 Query 421 VEIRKSAPAQ 430 VE S PAQ Sbjct 417 VEFAGSVPAQ 426 >gi|118464338|ref|YP_882289.1| P450 heme-thiolate protein [Mycobacterium avium 104] gi|118165625|gb|ABK66522.1| P450 heme-thiolate protein [Mycobacterium avium 104] Length=427 Score = 630 bits (1624), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 323/430 (76%), Positives = 364/430 (85%), Gaps = 3/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RY GEALLALYR RGP+I+AG G GYT LLGAEAN+FVFANADAFSW TFE+L V Sbjct 1 MRYRPGEALLALYRRRGPVIDAGAGRRGYTLLLGAEANKFVFANADAFSWRATFENLALV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRSVVAPGLRH +Q YV TMVS ID VIDGW+PGQRLD+YQ Sbjct 61 DGPTALIVSDGDDHRRRRSVVAPGLRHRQIQDYVTTMVSCIDRVIDGWRPGQRLDVYQHC 120 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 R+AVRRSTAESLFG+RLAVHSD LGE LQPLLDLT +PPQ++ LQ+R+N+P WRRAMAAR Sbjct 121 RAAVRRSTAESLFGRRLAVHSDALGEYLQPLLDLTHQPPQLVGLQRRINAPAWRRAMAAR 180 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 +RI++L+D IA+AR AP PDDHMLT LI G +EG L+DNEIRD+IVSL+TAGYETTS Sbjct 181 QRINNLVDTLIAEARAAPNPDDHMLTMLIDGRGDEGYALNDNEIRDAIVSLVTAGYETTS 240 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWA+Y LL+ PG W +AA EV RVL GR+PAA DLS LTYLNGVVHETLRLY PGVI Sbjct 241 GALAWAVYLLLSQPGAWATAAGEVRRVLAGRLPAAADLSGLTYLNGVVHETLRLYPPGVI 300 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRV+RDL F+G RIR+GRLLIFS YVTHRLPEIWPEP F P RW+P+A YR+PAPH Sbjct 301 SARRVMRDLRFEGRRIRSGRLLIFSPYVTHRLPEIWPEPMRFAPERWNPDAPGYRRPAPH 360 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFS GLHRC+GA MATTEMTV+LARL+AR L+LPAQ R+RAAN AALRP PGLT Sbjct 361 EFIPFSAGLHRCVGAAMATTEMTVMLARLLARTRLRLPAQ---RLRAANVAALRPTPGLT 417 Query 421 VEIRKSAPAQ 430 VE+ S PAQ Sbjct 418 VEVIDSVPAQ 427 >gi|254775551|ref|ZP_05217067.1| P450 heme-thiolate protein [Mycobacterium avium subsp. avium ATCC 25291] Length=427 Score = 627 bits (1617), Expect = 1e-177, Method: Compositional matrix adjust. Identities = 323/430 (76%), Positives = 363/430 (85%), Gaps = 3/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RY GEALLALYR RGP+I+AG G GYT LLGAEAN+FVFANADAFSW TFE+L V Sbjct 1 MRYRPGEALLALYRRRGPVIDAGAGRRGYTLLLGAEANKFVFANADAFSWRATFENLALV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRSVVAPGLRH +Q YV TMVS ID VIDGW+PGQRLD+YQ Sbjct 61 DGPTALIVSDGDDHRRRRSVVAPGLRHRQIQDYVTTMVSCIDRVIDGWRPGQRLDVYQHC 120 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 R+AVRRSTAESLFG+RLAVHSD LGE LQPLLDLT +PPQ++ LQ+R+N+P WRRAMAAR Sbjct 121 RAAVRRSTAESLFGRRLAVHSDALGEYLQPLLDLTHQPPQLVGLQRRINAPAWRRAMAAR 180 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 +RI++L+D IA+AR AP PD HMLT L+ G +EG TLSDNEIRD+IVSL+TAGYETTS Sbjct 181 QRINNLVDTLIAEARAAPNPDGHMLTMLVDGRGDEGYTLSDNEIRDAIVSLVTAGYETTS 240 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWA+Y LL+ PG W +AA +V RVL GR PAA DLS LTYLNGVVHETLRLY PGVI Sbjct 241 GALAWAVYLLLSQPGAWAAAAGDVRRVLAGRPPAAADLSGLTYLNGVVHETLRLYPPGVI 300 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRV+RDL F+G RIR+GRLLIFS YVTHRLPEIWPEP F P RWDP+A YR+PAPH Sbjct 301 SARRVMRDLRFEGRRIRSGRLLIFSPYVTHRLPEIWPEPRRFAPERWDPDAPGYRRPAPH 360 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFS GLHRC+GA MATTEMTV+LARL+AR L+LPAQ R+RAAN AALRP PGLT Sbjct 361 EFIPFSAGLHRCVGAAMATTEMTVMLARLLARTRLRLPAQ---RLRAANVAALRPTPGLT 417 Query 421 VEIRKSAPAQ 430 VE+ S PAQ Sbjct 418 VEVIDSVPAQ 427 >gi|41407471|ref|NP_960307.1| hypothetical protein MAP1373c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395823|gb|AAS03690.1| hypothetical protein MAP_1373c [Mycobacterium avium subsp. paratuberculosis K-10] Length=427 Score = 624 bits (1608), Expect = 1e-176, Method: Compositional matrix adjust. Identities = 323/430 (76%), Positives = 360/430 (84%), Gaps = 3/430 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RY GEALLALYR RGP+I+AG G HGYT LLGAEAN+FVFANADAFSW TFE+L V Sbjct 1 MRYRPGEALLALYRRRGPVIDAGAGRHGYTLLLGAEANKFVFANADAFSWRATFENLALV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRSVVAPGLRH +Q YV TMVS ID VIDGW+PGQRLD+YQ Sbjct 61 DGPTALIVSDGDDHRRRRSVVAPGLRHRQIQDYVTTMVSCIDRVIDGWRPGQRLDVYQHC 120 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 R+AVRRSTAESLFG RLAVHSD LGE LQPLLDLT +PPQ++ LQ+R+N+P WRRAMAAR Sbjct 121 RAAVRRSTAESLFGPRLAVHSDALGEHLQPLLDLTHQPPQLVGLQRRINAPAWRRAMAAR 180 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 +RI++L+D IADAR AP P+DHMLT LI G +EG TLSDNEIRD+IVSL+TAGYETTS Sbjct 181 QRINNLVDTLIADARAAPNPNDHMLTMLIDGRGDEGYTLSDNEIRDAIVSLVTAGYETTS 240 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 GALAWA+Y LL+ PG W +AA EV RVL G PAA DLS LTYLNGVVHETLRLY PGVI Sbjct 241 GALAWAVYLLLSQPGAWATAAGEVRRVLAGLPPAAADLSGLTYLNGVVHETLRLYPPGVI 300 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SARRV+RDL F G RIR+GRLLIFS YVTHRL EIWPEP F P RW+P+A YR+ APH Sbjct 301 SARRVMRDLRFKGRRIRSGRLLIFSPYVTHRLHEIWPEPRRFAPERWNPDAPGYRRAAPH 360 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EFIPFS GLHRC+GA MATTEMTV+LARL+AR L+LPAQ R+RAAN AALRP PGLT Sbjct 361 EFIPFSAGLHRCVGAAMATTEMTVMLARLLARTRLRLPAQ---RLRAANVAALRPTPGLT 417 Query 421 VEIRKSAPAQ 430 VE+ S PAQ Sbjct 418 VEVIDSVPAQ 427 >gi|254550675|ref|ZP_05141122.1| cytochrome P450 139 cyp139 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=269 Score = 542 bits (1397), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 269/269 (100%), Positives = 269/269 (100%), Gaps = 0/269 (0%) Query 162 MRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSD 221 MRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSD Sbjct 1 MRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSD 60 Query 222 NEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSAL 281 NEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSAL Sbjct 61 NEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSAL 120 Query 282 TYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTE 341 TYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTE Sbjct 121 TYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTE 180 Query 342 FRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQR 401 FRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQR Sbjct 181 FRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQR 240 Query 402 THRIRAANFAALRPWPGLTVEIRKSAPAQ 430 THRIRAANFAALRPWPGLTVEIRKSAPAQ Sbjct 241 THRIRAANFAALRPWPGLTVEIRKSAPAQ 269 >gi|333989273|ref|YP_004521887.1| cytochrome P450 [Mycobacterium sp. JDM601] gi|333485241|gb|AEF34633.1| cytochrome P450 139A3 Cyp139A3 [Mycobacterium sp. JDM601] Length=424 Score = 514 bits (1325), Expect = 9e-144, Method: Compositional matrix adjust. Identities = 261/423 (62%), Positives = 323/423 (77%), Gaps = 3/423 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RY G+AL L+R RGP+++AGVG +GY YL GAEAN+FVFAN+DAF+W F+ LVPV Sbjct 1 MRYRPGDALATLHRRRGPMVDAGVGRYGYVYLFGAEANKFVFANSDAFNWWDAFQVLVPV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDGADHRRRRS+V P H H+ Y+ M +N D VID W+PG +DI +L Sbjct 61 DGPTALIVSDGADHRRRRSLVQPAFHHRHLGNYLQVMAANADAVIDTWRPGDTIDIVAQL 120 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 RSA+RRS E+LFGQ +A H+DFLGEQLQPL+DLT+R PQV++ + R+ +P WRRAMAAR Sbjct 121 RSAIRRSAIEALFGQSMAGHADFLGEQLQPLMDLTQRLPQVLKAEARLKTPAWRRAMAAR 180 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 R+D+LI A+IA ART P DD++L TLI G +E G +L D+EIRD IVSLI AGYETTS Sbjct 181 ARVDELIYAEIARARTHPSADDNVLATLIGGRTEVGESLRDDEIRDQIVSLIAAGYETTS 240 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 A+ WA+YALL+ PG W++AA+EV V GR PA+ DL LTYLNGVVHETLRLY P VI Sbjct 241 AAMGWAVYALLSTPGVWQTAAAEVGDVTDGRTPASADLKNLTYLNGVVHETLRLYPPAVI 300 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 SAR+V R+L F G RI AGR L+FS YVTHRLPE+W +P F P RWDP+ YR+ AP+ Sbjct 301 SARKVTRELSFHGRRIHAGRTLVFSPYVTHRLPELWVDPLRFEPRRWDPSFPAYRRAAPY 360 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLT 420 EF+PF GG HRCIG+ AT E+TV+ AR++AR L LP Q RIRA +AAL+P GL Sbjct 361 EFLPFGGGTHRCIGSSFATAELTVMAARILARTSLSLPDQ---RIRAGGYAALQPRGGLM 417 Query 421 VEI 423 V++ Sbjct 418 VQV 420 >gi|257055961|ref|YP_003133793.1| cytochrome P450 [Saccharomonospora viridis DSM 43017] gi|256585833|gb|ACU96966.1| cytochrome P450 [Saccharomonospora viridis DSM 43017] Length=441 Score = 476 bits (1226), Expect = 3e-132, Method: Compositional matrix adjust. Identities = 250/424 (59%), Positives = 304/424 (72%), Gaps = 8/424 (1%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 VRY GE LLA YR RGP+ G Y YLLG EANRFVFAN++ F W + FE L+PV Sbjct 22 VRYLPGEFLLACYRRRGPVTGIG----RYVYLLGPEANRFVFANSELFRWREAFEGLIPV 77 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPT+LIVSDG DHRRRR +V P L H ++ Y+A M N D VID W+PG R+DIYQ+ Sbjct 78 DGPTSLIVSDGPDHRRRRRLVQPALHHRQIENYLAIMAENADAVIDRWRPGHRVDIYQQF 137 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 RSA+RRST +SLFG+RLA S+F G QLQ LLDL PQ + +QR+ +P WRRAMAAR Sbjct 138 RSAIRRSTIQSLFGKRLASESEFFGTQLQTLLDLIDHLPQTVAWKQRLATPQWRRAMAAR 197 Query 181 KRIDDLIDAQIADAR-TAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETT 239 RID+ I +IA AR + DDH+L +L+ G + G TLSD EIRD +V+LI AGYETT Sbjct 198 TRIDERIADEIARARLESTDADDHVLASLVHGKDDAGDTLSDQEIRDQVVTLIAAGYETT 257 Query 240 SGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGV 299 S A AWA+YA+L+ PG W+ AA EV VLG R P DLS L YLNGVV ETLRLYSP V Sbjct 258 SAAAAWAVYAMLSTPGVWDRAAEEVRGVLGDRPPGRGDLSKLDYLNGVVRETLRLYSPVV 317 Query 300 ISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAP 359 +SAR+V F G +++AG +L++S YVTHRLPE+WP+P FRP RW P +YRKPAP Sbjct 318 MSARKVATGFDFAGRKVKAGDMLLYSPYVTHRLPELWPDPLRFRPQRWIPTEPEYRKPAP 377 Query 360 HEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGL 419 HE++PFS G HRCIGA A TE+TV+LARL+AR L LP Q RIR +FAA+RP GL Sbjct 378 HEYLPFSAGPHRCIGATFALTELTVMLARLLARTSLLLPEQ---RIRPTSFAAMRPARGL 434 Query 420 TVEI 423 V++ Sbjct 435 LVDV 438 >gi|336457825|gb|EGO36819.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=428 Score = 450 bits (1158), Expect = 2e-124, Method: Compositional matrix adjust. Identities = 266/448 (60%), Positives = 298/448 (67%), Gaps = 41/448 (9%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 VRY GEALLALYR RGP+I+AG G HGYT LLGAEAN+FVFANADAFSW TFE+L V Sbjct 4 VRYRPGEALLALYRRRGPVIDAGAGRHGYTLLLGAEANKFVFANADAFSWRATFENLALV 63 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDG DHRRRRSVVAPGLRH +Q YV TMVS ID VIDGW+PGQRLD+YQ Sbjct 64 DGPTALIVSDGDDHRRRRSVVAPGLRHRQIQDYVTTMVSCIDRVIDGWRPGQRLDVYQHC 123 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAAR 180 R+AVRRSTAESLFG RLAVHSD LGE LQPLLDLT +PPQ++ LQ+R+N+P WRRAMAAR Sbjct 124 RAAVRRSTAESLFGPRLAVHSDALGEHLQPLLDLTHQPPQLVGLQRRINAPAWRRAMAAR 183 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 +RI++L+D IADAR AP P+DHMLT LI G +EG TLSDNEIRD+IVSL+TAGYETTS Sbjct 184 QRINNLVDTLIADARAAPNPNDHMLTMLIDGRGDEGYTLSDNEIRDAIVSLVTAGYETTS 243 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETL-----RLY 295 GALAWA+Y LL+ PG W +AA EV RVL G PAA DLS LTYLNGVVHE L Sbjct 244 GALAWAVYLLLSQPGAWATAAGEVRRVLAGLPPAAADLSGLTYLNGVVHEAAVPARGDLR 303 Query 296 SPGVISARRVLR------DLWFDGHRIR---AGRLLIFSAYVTHRLPEIWPEPTEFRPLR 346 +PG AR L+ D +R A R + + + R E R R Sbjct 304 APG--DARSALQGQADPIGAAVDLQPVRHPPASRNMARAKAIRTRT-------VEPRCSR 354 Query 347 WDPNAADYRKPAPHEFIPFSGGL---HRCIGAVMATTEMTVILARLVARAMLQLPAQRTH 403 P A P P GG HR G A A PA T Sbjct 355 VSPGGAARVHPVQCGAAPLRGGRDGHHRDDGDARA--------------AAGPHPAAVTR 400 Query 404 RIRA-ANFAALRPWPGLTVEIRKSAPAQ 430 A AN AALRP PGLTVE+ S PAQ Sbjct 401 SAPARANVAALRPTPGLTVEVIDSVPAQ 428 >gi|254550676|ref|ZP_05141123.1| P450 heme-thiolate protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=122 Score = 251 bits (641), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 121/122 (99%), Positives = 122/122 (100%), Gaps = 0/122 (0%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 +RYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV Sbjct 1 MRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPV 60 Query 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL Sbjct 61 DGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQEL 120 Query 121 RS 122 RS Sbjct 121 RS 122 >gi|284042314|ref|YP_003392654.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283946535|gb|ADB49279.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=479 Score = 200 bits (508), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 142/417 (35%), Positives = 210/417 (51%), Gaps = 21/417 (5%) Query 1 VRYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFV-FANADAFSWSQ-TFESLV 58 VR PL LLA YR GP+ + V ++LG EAN ++ ++A F W + +F LV Sbjct 47 VRDPL-PILLAAYREYGPIFSLRVFHGRVVFMLGPEANHYITVSHASNFHWREGSFGDLV 105 Query 59 PVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQ 118 P+ G L+ DGA HRR R ++ P + TMV +D WQPGQ +D+Y Sbjct 106 PLLG-DGLLTIDGAYHRRARRIMLPAFHRERIAAAGDTMVEETLRSLDRWQPGQLVDVYH 164 Query 119 ELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRR-----PPQVMRLQQRVNSPGW 173 R R ++LFG + D G + +D R +R + +P W Sbjct 165 WARELALRVAMKALFG----LDPDEEGAGRRAAVDFERALSFYGTDFAVRTMRGPLTP-W 219 Query 174 RRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEE--GTTLSDNEIRDSIVSL 231 RR AAR+ +D +I A+I R P P+ + +L+ +E G L+D E+RD +++L Sbjct 220 RRMQAARRTLDTIIYAEIERRRRHPDPERPDVMSLLLEARDEDGGEPLTDTEVRDQVMTL 279 Query 232 ITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDL-SALTYLNGVVHE 290 + AG++TT+ +++ +Y L P +E VL GR P +L S L L V+ E Sbjct 280 LFAGHDTTTSTVSFMLYELARHPAALAKVLAEQDTVLAGRTPTVAELTSGLPELEMVLDE 339 Query 291 TLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPN 350 TLRLY + RR + FDG + AG + +S++ +HRLP++WPEP F P R+ P Sbjct 340 TLRLYPAAWVGPRRSVETFEFDGRTVPAGAYVNYSSWASHRLPDVWPEPEAFVPERFAPA 399 Query 351 AADYRKPAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIR 406 A R P +IPF GG CIG E+ I+ L+ R L+L RT +R Sbjct 400 A---RAALPKGAYIPFGGGSRTCIGMRFGQLEIKTIVTLLLQRHRLELFPGRTMTVR 453 >gi|229119397|ref|ZP_04248697.1| Cytochrome P450 hydroxylase [Bacillus cereus Rock1-3] gi|228664075|gb|EEL19616.1| Cytochrome P450 hydroxylase [Bacillus cereus Rock1-3] Length=470 Score = 190 bits (483), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 129/426 (31%), Positives = 202/426 (48%), Gaps = 31/426 (7%) Query 12 LYRWRGPLINAGVGGH-GYTYLLGAEANRFVFANADAFSWSQTF-----ESLVPVDGPTA 65 L+ G ++ G G Y + G E N + N D F S + +SL+ Sbjct 44 LHNTYGKVVALGQGEKPSYVFAFGPELNERILTNPDLFKVSSSLVKIPKDSLLGRMFFNN 103 Query 66 LIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVR 125 LI+ G H++ R ++ P ++ Y MV + + WQ +++ E+++ + Sbjct 104 LIMMSGEKHKQHRRLMQPAFHREQIKTYCTDMVQLTQRLSNSWQENSVIELNHEMKTLTQ 163 Query 126 RSTAESLFGQRLAVHSDFLG----EQLQPLLDLTRRPPQVMRLQQRVNSPG--WRRAMAA 179 R ++LFG D +G + + LL +T P +N PG + RA+ + Sbjct 164 RIAVKTLFGLYDEAELDQMGRLIYQMTKSLLFVTLAP---------INLPGTPYNRALRS 214 Query 180 RKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETT 239 +++++ + A IA+ R D +L +LI E+GT L+D+E+ +L AG+ETT Sbjct 215 AEQLNNHVRAMIAEKRLETNATD-VLASLIQARDEDGTQLNDDELVGHTFTLYVAGHETT 273 Query 240 SGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGV 299 + AL WAI+ L P E+ LGG P + L +L+ L+GV+ ETLRL P Sbjct 274 ANALTWAIFLLSQHPDILYRLLEELDGTLGGCDPTIEKLGSLSLLDGVIKETLRLLPPAG 333 Query 300 ISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAP 359 I R I + F+ +THRLPE++ EP F+P RW D K +P Sbjct 334 IGVRITSDSCKLGDFTIPKDTNVFFNQMITHRLPELYDEPDCFKPERW-----DIIKRSP 388 Query 360 HEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGL 419 +E++PFS G H CIG A EM VILA L+ R Q A H + + +RP G+ Sbjct 389 YEYLPFSAGQHMCIGWNFALQEMKVILAVLLQR--FQFSA--VHNAKISPNMMMRPKYGM 444 Query 420 TVEIRK 425 + I K Sbjct 445 PMYILK 450 >gi|254409384|ref|ZP_05023165.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] gi|196183381|gb|EDX78364.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] Length=458 Score = 179 bits (453), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 120/396 (31%), Positives = 203/396 (52%), Gaps = 30/396 (7%) Query 43 ANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNID 102 ++D F + + P+ G T+LI+ DG H+ R ++ P L + Y + ++ +I Sbjct 64 TSSDQFELGKVTDVFRPLTGSTSLIMLDGQQHQVMRGLLMPPLHGKQLPTY-SRLIRDIT 122 Query 103 T-VIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQV 161 T I WQPG L I + + +FG + D L + ++P L+ P Sbjct 123 TDAIADWQPGSSLPIRDYMSDISLQVILRVVFGLNVGDRYDRLKQLIEPFLNNITSPLNS 182 Query 162 MR-----LQQRVN--SPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSE 214 + LQQ + SP W + + R++IDDLI QIA RT P DD +L+ L+S + Sbjct 183 IHFFWTPLQQDLGGWSP-WGKFVRQRQQIDDLIYEQIAHRRTEPEGDD-ILSLLMSARDQ 240 Query 215 EGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPA 274 G +L+D ++RD +++L+ G+ETT+ ALAWA Y L P E E+ + G P Sbjct 241 MGQSLTDVQLRDQLITLLLLGHETTASALAWAFYWLHRQPLCLEKLTQELDSL--GENPD 298 Query 275 ADDLSALTYLNGVVHETLRLYSPGVISA-RRVLRDLWFDGHRIRAGRLLIFSAYVTHRLP 333 D ++ L YL V E LR+Y +I+ R+V + G+ + G + + Y+THR Sbjct 299 PDAIAQLPYLTAVCKEALRVYPIALIAQPRQVKASVQIQGYELEPGAIAVPCIYLTHRRQ 358 Query 334 EIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARA 393 +++PEP +F+P R+ +++ +P+E+ PF GG CIG ++ EM ++LA +++R Sbjct 359 DVYPEPDQFKPERF-----VHQQFSPYEYFPFGGGSRSCIGMALSLFEMKLVLATVLSRY 413 Query 394 MLQLPAQRTHRIRAANFAALRPW-PGLTVEIRKSAP 428 L + +++PW G+T+ K+ P Sbjct 414 QLAIDPN----------TSVQPWRRGITIVPSKACP 439 >gi|315647692|ref|ZP_07900793.1| cytochrome P450 [Paenibacillus vortex V453] gi|315276338|gb|EFU39681.1| cytochrome P450 [Paenibacillus vortex V453] Length=467 Score = 178 bits (451), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 118/382 (31%), Positives = 185/382 (49%), Gaps = 33/382 (8%) Query 31 YLLGAEANRFVFANADAFSWSQTFESLVPVDGPTA--------LIVSDGAD-HRRRRSVV 81 + G E NR + +N + F S +LV + T L V D + H+ R ++ Sbjct 51 FAFGPELNRQILSNPNFFEMST---ALVKIPKDTVMGDLFYHNLRVDDAVEKHKEHRRLI 107 Query 82 APGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHS 141 P H ++RY M + + D W+ +DI E++ +R ++LFG + + Sbjct 108 QPAFLHSQIERYGQDMTLITEQLADEWRGRTLIDINTEMKKLTQRIALKTLFGVQNSEMM 167 Query 142 DFLGEQL----QPLLDLTRRPPQVMRLQQRVNSPG--WRRAMAARKRIDDLIDAQIADAR 195 D +G + + L T P +N P +RR++ ++++ I + I + R Sbjct 168 DTMGMLINRFTKSFLLATLAP---------LNIPFTPYRRSLRNAQQLNTQIRSMIHEKR 218 Query 196 TAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPG 255 D +L LI G EEG+ LSD E+ S+ TAG+ETT+ AL WA + L+ P Sbjct 219 QESDATD-VLAALIRGYDEEGSALSDEELVGHAFSIYTAGHETTANALTWAFFLLVQHPN 277 Query 256 TWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHR 315 + + E+ V+GG + LS L+ L+ VV E+LRL P I R DG+ Sbjct 278 IYANLMEELNAVMGGSHLTHEKLSRLSLLDYVVKESLRLLPPASIGTRITNAPCELDGYA 337 Query 316 IRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGA 375 + G + FS ++THRLPE++ +P F+P RW KP+ EF+PFS G H CIG Sbjct 338 LPEGTNVFFSQFITHRLPELYEDPNYFKPYRWQT-----IKPSAFEFLPFSAGPHMCIGW 392 Query 376 VMATTEMTVILARLVARAMLQL 397 A E+ ++LA L+ R L Sbjct 393 HFAMQELKIVLAVLLQRFNFSL 414 >gi|298242977|ref|ZP_06966784.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] gi|297556031|gb|EFH89895.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] Length=450 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 101/337 (30%), Positives = 167/337 (50%), Gaps = 12/337 (3%) Query 68 VSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRS 127 S+G HR++R +V P + +Y TMV+ + GW G+ +++ +++ R Sbjct 91 TSEGDFHRQQRRLVQPSFHRQRIDQYADTMVNYTQDTLCGWHAGEEVEMASQMQRLTLRI 150 Query 128 TAESLFGQRLAVHSDFLGEQLQPLLDLT-------RRPPQVMRLQQRVNSPGWRRAMAAR 180 +++F D LG +++ R P + L R + R Sbjct 151 ILKTMFNVDDMKQIDTLGAAFNTVINQAPHRFFWLRGP--LANLVGRTTKDQDEQFTNGR 208 Query 181 KRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTS 240 +D + I R+ + +L+ L++ S+EG +LSD +IRD +++L+ AG+ET Sbjct 209 TTLDTFVSTLIQQRRSNKQDQGDILSMLLAA-SDEGESLSDQQIRDQVMTLMAAGHETAQ 267 Query 241 GALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVI 300 +L W Y L P +E +E+ VL GR P DL+ L YL V++E+ R+Y P Sbjct 268 NSLCWTFYLLAQHPRVYEKLLAELRTVLQGRAPTMKDLAQLPYLEWVMNESWRIYPPAWR 327 Query 301 SARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 RR + D+ DG+R AG + + +VTH +PE+W +P FRP RWDP A +K Sbjct 328 IGRRAIEDIELDGYRFPAGTIFLLHQWVTHHMPELWGDPENFRPERWDP--AHQQKLPQG 385 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQL 397 + PF GG CIG A E+ ++LA ++ + Q+ Sbjct 386 VYFPFGGGPRICIGMPFAQMEVRLLLATILQQYYPQI 422 >gi|119485435|ref|ZP_01619763.1| cytochrome P450 [Lyngbya sp. PCC 8106] gi|119457191|gb|EAW38317.1| cytochrome P450 [Lyngbya sp. PCC 8106] Length=457 Score = 176 bits (446), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 111/392 (29%), Positives = 190/392 (49%), Gaps = 18/392 (4%) Query 23 GVGGHGYTYLLGAEANRFVFA-NADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVV 81 G + +EA +F + D F + P+ G +LI+ DG H+R R ++ Sbjct 43 GFNSPPIVFFSNSEAIEAIFTTDTDKFELGKITHVFQPLTGSQSLIMQDGKRHQRLRQLL 102 Query 82 APGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHS 141 P L + Y T+ + W PG + I + + G + Sbjct 103 MPSLHSKQLPAYGQTICNLTLKATQNWSPGDFISIRDYTSEIALEVILQVVLGLKENRRY 162 Query 142 DFLGEQLQPLLDLTRRPPQVMR-----LQQRVNSPG-WRRAMAARKRIDDLIDAQIADAR 195 L ++P L+ +P ++ LQQ + W + + RK+IDDLI A+IA+ R Sbjct 163 FQLKHLIEPYLESVNKPLNSIQFFLPPLQQNLGQKSPWGKFLKQRKKIDDLIYAEIAERR 222 Query 196 TAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPG 255 T P +D +L+ LIS E G L+D E+RD +++L+ G++TT+ ALAWA Y + P Sbjct 223 TKPLGED-VLSLLISAKDEAGQPLTDQELRDQLITLLLLGHDTTASALAWAFYWIHRYPK 281 Query 256 TWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRD-LWFDGH 314 E+ + G P D+ L YLN V ETLR++ +IS RV+++ + + + Sbjct 282 IVNQLVEELNSL--GENPDPMDIVQLPYLNAVCQETLRIHPIALISQPRVVKESIKIENY 339 Query 315 RIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIG 374 + + G +L+ ++ H +I+P +F +PN +K +P+E++PF GG CIG Sbjct 340 QFKPGTILVPCIHLAHHREQIYPNSKQF-----NPNRFLEQKFSPYEYLPFGGGNRSCIG 394 Query 375 AVMATTEMTVILARLVARAMLQLPAQRTHRIR 406 ++ EM +ILA ++ QL ++H ++ Sbjct 395 MALSLFEMKLILATILLNY--QLAFNQSHVVK 424 >gi|190333631|gb|ACE73823.1| putative cytochrome P450 [Streptomyces peucetius ATCC 27952] Length=436 Score = 174 bits (442), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 112/340 (33%), Positives = 176/340 (52%), Gaps = 10/340 (2%) Query 66 LIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGW----QPGQRLDIYQELR 121 L+ ++G R +R VAP R ++R+ MV + ++ W + GQ LD E++ Sbjct 9 LVTTEGEVWRAQRRTVAPTFRREPLERFAGVMVDSTQRMLGRWDRIARYGQTLDARTEMQ 68 Query 122 SAVRRSTAESLFGQRLAVHSDFLGEQLQPLLD-LTRRPPQVMRLQQRVNSPGWRRAMAAR 180 S A LF + + LG + L+ + + V + ++V +P RR AAR Sbjct 69 SLTLEILARCLFRADWSRDALALGSAVATQLEHINSKLIAVADIPEKVPTPRNRRFRAAR 128 Query 181 KRIDDLIDAQIADARTAPRPDD--HMLTTLI-SGCSEEGTTLSDNEIRDSIVSLITAGYE 237 K +DD + IA+ R P D +L+ L+ + E G ++D ++RD +++L AG+E Sbjct 129 KLLDDTVYRLIAERRAEPADGDAQDLLSMLMHTPDPETGRLMTDEQLRDQVMTLFIAGHE 188 Query 238 TTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSP 297 T + L+W + L T P + A +EV +VLGGR P +DL L YL + E LRLY P Sbjct 189 TVAATLSWICHLLSTRPAETDRARAEVQKVLGGRTPTMEDLPQLKYLKLFIQEALRLYPP 248 Query 298 GVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKP 357 AR L+D G+ I AG L+ S Y+THR PE W P F P R+ A R Sbjct 249 LWQVARMPLKDDVLSGYHIPAGSFLLLSTYITHRNPEFWDNPEGFDPERFTRERAAAR-- 306 Query 358 APHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQL 397 + + ++P++GG C+G A E+T+++A L+ R L + Sbjct 307 SRYAYVPYAGGPRNCVGMAFANMELTIVVACLLQRFHLDM 346 >gi|297625126|ref|YP_003706560.1| cytochrome P450 [Truepera radiovictrix DSM 17093] gi|297166306|gb|ADI16017.1| cytochrome P450 [Truepera radiovictrix DSM 17093] Length=436 Score = 174 bits (440), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 119/359 (34%), Positives = 176/359 (50%), Gaps = 7/359 (1%) Query 44 NADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDT 103 +A F S ++ L P G L+ SDG RR+R + P H V Y MV Sbjct 60 DAAKFRKSPAYKVLEPTLG-QGLLTSDGDFWRRQRRLAQPAFHHARVASYADIMVRYAQE 118 Query 104 VIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDL-TRRPPQVM 162 W+PGQ L I E+ + R A++LF + + + E L+ LL + T + Sbjct 119 RRASWRPGQLLAINHEMMALTLRVVAKALFDTDITAQAGRVKEALETLLHVATETITTPI 178 Query 163 RLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDN 222 L + +P RR+ A + +D+++ I R + +L+ L++ +EG +SD Sbjct 179 PLPAWLPTPRNRRSQRATRALDEIVYEMIDARRRSGDDTGDLLSMLLAAVDDEGQGMSDK 238 Query 223 EIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALT 282 +RD V+LI AG+ETT+ AL WA Y L P + EVARVLGGR P DLSAL Sbjct 239 AVRDEAVTLILAGHETTANALTWAFYLLAQHPEVEAALREEVARVLGGRAPTFADLSALR 298 Query 283 YLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEF 342 Y + +V ET+RL+ P R ++ + AG +++ +V HR P + EP F Sbjct 299 YTDLIVKETMRLFPPAPEIGRLATEEVALGDTVVPAGSIVVIPIHVVHRDPRWFREPEAF 358 Query 343 RPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLV-ARAMLQLPAQ 400 RP R+ AA + ++PF GG CIG A E T++LA L+ R + P Q Sbjct 359 RPERFADTAALPK----FAYLPFGGGPRICIGNAFAQMEATLLLATLIQGRRLCLAPGQ 413 >gi|159901767|ref|YP_001548012.1| cytochrome P450 [Herpetosiphon aurantiacus DSM 785] gi|159894806|gb|ABX07884.1| cytochrome P450 [Herpetosiphon aurantiacus DSM 785] Length=446 Score = 173 bits (438), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 109/342 (32%), Positives = 169/342 (50%), Gaps = 7/342 (2%) Query 64 TALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSA 123 L+ S+ + HRR+R +VAP +H H+ Y T+ + D W GQR+DI QE+ Sbjct 86 NGLLTSENSFHRRQRKLVAPAFQHRHIANYANTISAYTDETQARWHQGQRIDIAQEMMRL 145 Query 124 VRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQ-VMRLQQRVNSPGWRRAMAARKR 182 R +++LF + +D LG L +L+ + ++ + P +R AA + Sbjct 146 TLRVMSQTLFSTDINTEADALGRALTTVLNYSNSVANTLIHIPYHWPIPQHKRVHAAIAQ 205 Query 183 IDDLIDAQIADARTAPRPDDHMLTTLISGCSEE-GTTLSDNEIRDSIVSLITAGYETTSG 241 +D I I + RT P + +L+ L+ ++ G+ ++D ++RD +++L AG+ETT+ Sbjct 206 LDTTIQRLIHERRTQPTSTNDLLSVLLQAHDDDDGSFMTDTQVRDELMTLFLAGHETTAN 265 Query 242 ALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVIS 301 AL W Y L P EV +G R+P DDLS L Y V E+LRLY P + Sbjct 266 ALTWTWYLLAHHPHIATKIKDEVDSTVGTRLPTMDDLSKLPYTLQVFKESLRLYPPVYMI 325 Query 302 ARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWD-PNAADYRKPAPH 360 AR+ + + + G + S Y HR + + P +F P R+D + A K A Sbjct 326 ARKASQAFELGSYHVPEGMAFVVSPYTIHRRADYFDHPEDFNPDRFDTSHEASIPKNA-- 383 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQL-PAQR 401 +IPFS G CIG A E ++LA + R L L P QR Sbjct 384 -YIPFSLGPRNCIGNHFAMMEGHLMLAIIAQRMRLLLAPNQR 424 >gi|288963095|ref|YP_003453374.1| cytochrome P450 [Azospirillum sp. B510] gi|288915347|dbj|BAI76830.1| cytochrome P450 [Azospirillum sp. B510] Length=478 Score = 172 bits (435), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 117/422 (28%), Positives = 194/422 (46%), Gaps = 21/422 (4%) Query 12 LYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPVDGP-----TAL 66 + R G + + + + G NR + ++ + F E +PV +L Sbjct 39 MQRRYGEICSWAKNDQKFINIYGPRYNRLLLSDPETFVIDAFREHHLPVGSSFERLTLSL 98 Query 67 IVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRR 126 + +G H+R R ++ P R + ++RY +V D + GWQPG+ + ++ V Sbjct 99 MRLNGNAHQRHRKMIQPAFRTYQLERYRQIIVDETDRFLAGWQPGESRQLDEDFLKLVTL 158 Query 127 STAESLFGQRLAVHSDFLGEQLQPLL-DLTRRPPQVMRLQQRVNSPG--WRRAMAARKRI 183 + ++FG + +D GE+L L+ L R+ + L N PG +R + +I Sbjct 159 ISMRTMFG--MEAETD--GERLVALIKQLIRQFSSPLILLLPFNVPGLPFRAILDTTDKI 214 Query 184 DDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGAL 243 + + I R D +L ++ E G+ ++ E+ +++ E + AL Sbjct 215 ERFVMDAIERKRADLDRYDDVLAEMMKARDETGSGFTNEELVAHAYTILCQ--EAAASAL 272 Query 244 AWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISAR 303 W + L P + A+E+ L G P +DL LTYL+ V+ E LRL+ R Sbjct 273 LWTFFLLDCHPDVYRRVAAEIDEKLHGAPPGMNDLKELTYLDRVLKEALRLFPSSPFGLR 332 Query 304 RVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFI 363 +RD H ++ G + FS+YVTHR+PEI+ P F P RW A +P E++ Sbjct 333 YAVRDCTLGDHDLKKGTGIFFSSYVTHRMPEIFENPLAFDPDRWTSAAC-----SPFEYL 387 Query 364 PFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEI 423 PF G H CIG +A E+ VILA ++ R M++L Q RI +L P GL + Sbjct 388 PFGAGAHHCIGQGLALVELKVILAMILQRFMVRL--QPKTRIDLTVKISLVPKQGLAAVL 445 Query 424 RK 425 R+ Sbjct 446 RR 447 >gi|339010031|ref|ZP_08642602.1| cytochrome P450 [Brevibacillus laterosporus LMG 15441] gi|338773301|gb|EGP32833.1| cytochrome P450 [Brevibacillus laterosporus LMG 15441] Length=437 Score = 172 bits (435), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 111/345 (33%), Positives = 165/345 (48%), Gaps = 9/345 (2%) Query 65 ALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAV 124 L ++G R R ++AP ++ Y T++ + I+ WQ G+ +I ++ + Sbjct 85 GLFTANGEHWLRNRRMMAPEFHQKRIESYGKTIIEVTNRYIENWQEGETREIKIDMLNLA 144 Query 125 RRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAARKRID 184 +SLFG + L + LQ +L + + + PG+ K +D Sbjct 145 LDVVMKSLFGHNNTIDEGKLIQALQTILRYYAKA-----VMFPIPLPGYSNYKRCAKEMD 199 Query 185 DLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALA 244 D+I I+ R++ D +L L+S E G L D +IRD +++LI AG+ETTS ALA Sbjct 200 DMILQLISSRRSSGIYGDDLLGMLLSMRDENGEGLDDRQIRDEVMTLIVAGHETTSAALA 259 Query 245 WAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARR 304 +A Y L P E A+E++ VL G +P DL L Y VV+ETLRL SP I R+ Sbjct 260 FAFYLLSENPDVTEKMAAEISEVLDGHLPHIQDLPNLQYTTMVVNETLRLRSPAYILLRQ 319 Query 305 VLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAP-HEFI 363 D+ + I +++ S YV HR P + +P FRP RW A K P + Sbjct 320 AAEDIQIGEYMIPKDSIVLVSQYVMHRDPRYFEDPLVFRPERW---ADGLEKKLPTFVYF 376 Query 364 PFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAA 408 PF GG CIG A E +ILA +V R L Q + A+ Sbjct 377 PFGGGPRMCIGQRFAMAEAVLILATIVQRYKLTAVNQDKLEVNAS 421 >gi|345013216|ref|YP_004815570.1| cytochrome P450 [Streptomyces violaceusniger Tu 4113] gi|344039565|gb|AEM85290.1| cytochrome P450 [Streptomyces violaceusniger Tu 4113] Length=453 Score = 171 bits (434), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 126/427 (30%), Positives = 197/427 (47%), Gaps = 24/427 (5%) Query 2 RYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPVD 61 R PL LA G L+ +G E R V N F F+ + Sbjct 34 RRPL--QFLASLPAHGDLVEVRLGPSRAYLACHPELVRQVLLNPRVFDKGGVFDKARQLL 91 Query 62 GPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELR 121 G +L VS G DHR +R ++ P + Y A + + I W+PG+ LD+ + Sbjct 92 G-NSLSVSRGEDHRTQRRMIQPAFHTPKIADYTAAVADDTRAAIGSWEPGRTLDLSDTMH 150 Query 122 SAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLT----RRPPQVMRLQQRVNSPGWRRAM 177 + + R A +LF + + E L ++ +R + + +++ +PG RR Sbjct 151 ALLMRVAARTLFST--GIDEATIDEARHCLRIVSHGIYKRTMAPLGIMEKLPTPGNRRYD 208 Query 178 AARKRIDDLIDAQIADARTAPRPDDHMLTTLI-SGCSEEGTTLSDNEIRDSIVSLITAGY 236 A R+ ++D I D R + +L+TL+ + E G L D E+ D +V+ + AG Sbjct 209 RANARLRQIVDEMIRDRRRSGADHGDLLSTLLRAEHPETGEGLDDGEVLDQVVTFLVAGS 268 Query 237 ETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYS 296 ETT+ LA+ + L P + +E+ L GR P +DL +L Y GV+ E+LRLY Sbjct 269 ETTASTLAFVFHLLGAHPEVEKRVHAEIDEALKGRSPTFEDLPSLEYTRGVITESLRLYP 328 Query 297 PGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRK 356 P ++ R + G I AG ++++SA H P ++P+P F P RW P+ A K Sbjct 329 PSWMAMRVTAAETDLGGRTIPAGTMILYSAQALHHNPGLFPDPERFDPERWFPDRA---K 385 Query 357 PAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRP 415 P +PF G H+CIG V+A TE +I+A + +R R+R LRP Sbjct 386 DVPRGALLPFGAGSHKCIGDVLALTETALIVATIASR----------WRLRPVPGTTLRP 435 Query 416 WPGLTVE 422 P T+E Sbjct 436 EPKATLE 442 >gi|298250768|ref|ZP_06974572.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] gi|297548772|gb|EFH82639.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] Length=457 Score = 171 bits (434), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 115/421 (28%), Positives = 196/421 (47%), Gaps = 8/421 (1%) Query 9 LLALYRWRGPLINAGVGGHGYTYLLGAE-ANRFVFANADAFSWSQTFESLV-PVDGPTAL 66 L+ ++R +GP+ +G AE + +A F ++ +++ PV G + Sbjct 39 LMRMWREQGPVSGFHMGPFALPAFFSAEHVQSILVEHAYDFDKGESIHNVLRPVIG-NGI 97 Query 67 IVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRR 126 S+G HRR+R ++AP + H+ Y MV + V WQ G R++I +E+ + Sbjct 98 FTSEGDFHRRQRKIMAPSFQPRHIASYADNMVYYGEQVQQRWQDGARINIDEEMTTITMS 157 Query 127 STAESLFGQRLAVHSDFLGEQLQPLLDLT-RRPPQVMRLQQRVNSPGWRRAMAARKRIDD 185 + LF + +D LG + L+ R +++ +P +RA A + Sbjct 158 IIGKVLFNVDVFTETDELGAAMATTLNFVGHRLARLLPTPYNWPTPQNKRAHQAIALLRS 217 Query 186 LIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAW 245 I I + R + + L+ L+ +EG + + ++ D ++L AG+ETT+ AL W Sbjct 218 RIQQMIEERRASAEEGNDFLSILLRARDDEGKPMDNEQLIDECLTLFGAGHETTAVALTW 277 Query 246 AIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRV 305 A Y L P + E VLGGRV DL+ L V ETLR+Y P R Sbjct 278 AWYLLAQHPEQYRKLQEEARSVLGGRVATYADLTKLPCSQQVFKETLRMYPPAYTMGRAA 337 Query 306 LRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAP-HEFIP 364 L+D+ DG+++ G +++ + YV H P+ +P P EF P R+ P + K P + ++P Sbjct 338 LKDIVIDGYQVHKGDVVLIAPYVMHNRPDYFPRPFEFDPERFTP---EREKQLPRYAYLP 394 Query 365 FSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIR 424 F G CIG A E ++L+ L R +L + + + LRP + + +R Sbjct 395 FGAGPRICIGNYFAMMEGQLLLSTLAQRVTFELVPGQEIKPDPSKSLTLRPDQHVQMVVR 454 Query 425 K 425 + Sbjct 455 R 455 >gi|260653871|dbj|BAI44339.1| P450 [Streptomyces melanosporofaciens] Length=459 Score = 171 bits (433), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 122/418 (30%), Positives = 197/418 (48%), Gaps = 18/418 (4%) Query 9 LLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPVDGPTALIV 68 LA G L+ +G E R V N F F+ + G +L V Sbjct 45 FLASLPAHGDLVEVRLGPSRAYLACHPELVRQVLLNPRVFDKGGVFDKARQLLG-NSLSV 103 Query 69 SDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRST 128 S G DHR +R ++ P + Y A + + I W+PG+ LDI + + + R Sbjct 104 SRGEDHRYQRRMIQPAFHTPKIAAYTAAVADDTRAAIGSWEPGRTLDISDTMHALLMRVA 163 Query 129 AESLFGQRLAVHS-DFLGEQLQPLLD-LTRRPPQVMRLQQRVNSPGWRRAMAARKRIDDL 186 A +LF + + D L+ + D + +R + + +++ +PG RR A R+ + Sbjct 164 ARTLFSTGIDEATIDEARHCLRIVSDGIYKRTMAPLGIMEKLPTPGNRRYDRANARLRQI 223 Query 187 IDAQIADARTAPRPDDHMLTTLI-SGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAW 245 +D I + R + +L+TL+ + E G L D E+ D +V+ + AG ETT+ LA+ Sbjct 224 VDEMIRERRRSGADHGDLLSTLLRAEHPETGKGLDDGEVLDQVVTFLVAGSETTASTLAF 283 Query 246 AIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRV 305 + L P + +E+ +L GR P +DL +L Y GV+ E+LRLY P ++ R Sbjct 284 VFHLLGAHPEVEKRVHAEIDEILEGRSPTFEDLPSLEYTRGVITESLRLYPPSWMAMRVT 343 Query 306 LRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRW-DPNAADYRKPAPHEFIP 364 + G + AG ++++SA H PE++P+P F P RW A + + A +P Sbjct 344 AAETELGGRTVPAGTMILYSAQALHHNPELFPDPERFDPERWLGDRAKEVERGA---LLP 400 Query 365 FSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVE 422 F G H+CIG V+A TE +I+A + +R R+R LRP P T+E Sbjct 401 FGAGSHKCIGDVLALTETALIVATIASR----------WRLRPVPGTTLRPEPKATLE 448 >gi|325517539|gb|ADZ25011.1| cytochrome P450 hydroxylase [Sorangium cellulosum] Length=482 Score = 171 bits (432), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 117/373 (32%), Positives = 188/373 (51%), Gaps = 40/373 (10%) Query 55 ESLVPVD---GPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPG 111 E+ P+D G +LI DGA H R R ++ P + Y M + +DGW+ G Sbjct 72 EAAAPIDFLLGSNSLIRLDGARHTRDRKLLMPSFHGERMVAYAEMMRVIAERAVDGWELG 131 Query 112 QRLDIYQELRSAVRRSTAESLFG-------QRL-AVHSDFLGEQLQPLLDL--TRRPPQV 161 + + ++ E +FG RL A+ FL E +P++ L P ++ Sbjct 132 KPFSFLKAAQNITLSIMLECIFGVGPGELHDRLRALLPKFLHESSKPMISLLWATVPGKL 191 Query 162 MR------LQQRVNSPG----------WRRAMAARKRIDDLIDAQIAD--ARTAPRPDDH 203 +R L ++ G W R++ + ID+ + + IA AR +P D Sbjct 192 LRDVLVRGLAPAAHALGPAGSVVPAGTWARSL---REIDEFLYSHIAAQRARRSPEASD- 247 Query 204 MLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASE 263 +++ LI E+G SD E+RD +++++ AGYETT+ L WA+ +L P + E Sbjct 248 IISMLIEVRDEQGNAFSDAELRDEMMTMLVAGYETTAITLTWAMAKILEYPHVLAAIREE 307 Query 264 VARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLI 323 + RV+G R P+ + L YL+ + E LRLY P +AR++ F G+ + AG +L Sbjct 308 LDRVIGDRPPSGAAIGELRYLDATIKEVLRLYPPSPGTARKLHVPGRFGGYDLPAGVVLY 367 Query 324 FSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMT 383 S Y+ HR P+IWP+ PLR+DP+ +KP P +IPF GGL C+G A E+ Sbjct 368 PSIYLLHRRPDIWPD-----PLRFDPSRFLDKKPNPAAYIPFGGGLRTCLGMSFALFELK 422 Query 384 VILARLVARAMLQ 396 ++LA +++RA L+ Sbjct 423 LVLATILSRASLR 435 >gi|225874539|ref|YP_002755998.1| cytochrome P450 family protein [Acidobacterium capsulatum ATCC 51196] gi|225792929|gb|ACO33019.1| cytochrome P450 family protein [Acidobacterium capsulatum ATCC 51196] Length=464 Score = 170 bits (431), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 115/383 (31%), Positives = 181/383 (48%), Gaps = 15/383 (3%) Query 44 NADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDT 103 AD F +T + + + G LI SDG H+R+R + AP +Q Y A M Sbjct 83 QADKFIKERTQKRMKILLG-NGLITSDGEFHKRQRRIAAPAFHRQRIQAYGAVMTDRALA 141 Query 104 VIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMR 163 + + WQPG+ + E+ + A +L + + +++ ++DL + R Sbjct 142 MREEWQPGKEIGALAEMMRVTLQIVARTLLNTDVTAEVQQINDEVNAIMDLYNFLVALPR 201 Query 164 LQQRVN--SPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEG--TTL 219 + ++ PG R ARKR+D ++ IA+ R +L+ L+ +E + + Sbjct 202 AEAYLHWPIPGLMRFRRARKRLDAVVYRIIAEHRQEKTDGGDLLSMLLRSRDDEADHSGM 261 Query 220 SDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLS 279 +D ++RD I+++ AGYET + AL W Y L P E+ VL GR P +DL Sbjct 262 TDEQVRDEILTIFLAGYETVATALTWTWYLLAQNPEAEARMHEEIDTVLQGRTPTLEDLP 321 Query 280 ALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEP 339 L Y+ V E++RLY P R+ D+ +R+ AG + FS Y+ R PE WP+P Sbjct 322 QLKYVEMVFAESMRLYPPAWAMGRQATADVELGPYRLPAGSYVFFSQYIIQRNPEYWPDP 381 Query 340 TEFRPLRW--DPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQL 397 EFRP R+ D AA R + PF G +CIG A E ++LA + + L+L Sbjct 382 LEFRPERFSVDQKAARSR----FIYFPFGAGSRQCIGESFAWMEGVLVLATIAQKWRLRL 437 Query 398 -PAQRTHRIRAANFAALRPWPGL 419 P Q ++ LRP P + Sbjct 438 IPGQ---QVELQPKITLRPKPEI 457 >gi|294628911|ref|ZP_06707471.1| cytochrome P450 family protein [Streptomyces sp. e14] gi|292832244|gb|EFF90593.1| cytochrome P450 family protein [Streptomyces sp. e14] Length=450 Score = 170 bits (430), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 112/332 (34%), Positives = 167/332 (51%), Gaps = 7/332 (2%) Query 64 TALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSA 123 LI SD ADHRR+R +V P + Y M +GW+ GQ +++ +E+++ Sbjct 92 NGLITSDWADHRRQRRMVQPAFHPTRIAGYAEVMREECARHAEGWRAGQPVNVSEEMQAL 151 Query 124 VRRSTAESLFGQRLAVHSDFLGEQLQPLL--DLTRRPPQVMRLQQRVNSPGWRRAMAARK 181 R TA +LF +A HS ++ P++ RR L R+ R AA Sbjct 152 TARVTARALFSTEMAPHSVAEIQRSLPVMVHGAYRRAVDPTGLLARLPLAANREFDAALG 211 Query 182 RIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSG 241 R+ LI+ + D R + + +L+ L++ ++G +SD E+ D I++L+ AG ETT+ Sbjct 212 RLHSLIEGIVGDYRNSRQDRGDLLSALLAVRDDDGA-MSDQEVHDQIITLLLAGVETTAS 270 Query 242 ALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVIS 301 AL WA + L T P SEV VLGGR P D+ L + + ETLRLY P + Sbjct 271 ALTWAWHLLATHPEAEARLHSEVDSVLGGRAPTYADVPKLVHTQRIFTETLRLYPPAWMF 330 Query 302 ARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPN-AADYRKPAPH 360 R G R+ AG ++ S YV HR+P ++ P F P RW P A D + + Sbjct 331 TRTTTEPTELAGVRLPAGADILISPYVIHRVPGLFARPERFDPDRWLPERAKDVTRGS-- 388 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVAR 392 ++PF GG +CIG V T E T+ LA + +R Sbjct 389 -YLPFGGGSRKCIGDVFGTVEATLALAAIASR 419 >gi|190333627|gb|ACE73821.1| putative cytochrome P450 [Streptomyces peucetius ATCC 27952] Length=499 Score = 170 bits (430), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 110/366 (31%), Positives = 177/366 (49%), Gaps = 24/366 (6%) Query 65 ALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQ----PGQRLDIYQEL 120 LI S+G +R+R + P V + M ++D W+ Q +D+ ++ Sbjct 94 GLICSEGDFWKRQRRLCQPAFHRRLVNSFGENMTEVTGELLDRWEAASRSNQEVDVTLDM 153 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLL-DLTRRPPQVMRLQQRVNSPGWRRAMAA 179 +LFG S+ + ++ + + ++ + + L + V +P R A Sbjct 154 TRLALGVLGGALFGANWRQDSEVMAHAVEVAIGEAYKKFGKFVSLPESVPTPANLRFAKA 213 Query 180 RKRIDDLIDAQIADART--APRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYE 237 R+ +DD+I I RT PDD +L L++ ++G+ ++ ++R+ +++ + G+E Sbjct 214 RRSLDDVIYRVINARRTDRGEHPDD-LLEALMTATEDDGSGMTVEQVRNEVMTFMFGGHE 272 Query 238 TTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSP 297 T + L WA+Y L P + EV VLG RVP DDL L Y++ VV E+LRLY P Sbjct 273 TVASGLTWALYLLSRHPEVYGRMEQEVDEVLGSRVPTVDDLPQLPYIDRVVRESLRLYPP 332 Query 298 GVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKP 357 + +R D G+ I G +++ SA+VTHR PE WP P F P RW + + Sbjct 333 VSLISRTPQEDDTVMGYDIPKGSMVLLSAFVTHRHPEFWPNPEGFDPDRW----IELGEQ 388 Query 358 APHEFI--PFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRP 415 PH F PFSGG +CIG V EM ++LA + R R+R A+ P Sbjct 389 GPHRFAWWPFSGGPRKCIGDVFGLQEMKLVLAMMAQRV----------RVRLVPGHAVVP 438 Query 416 WPGLTV 421 PG+T+ Sbjct 439 KPGITL 444 >gi|239991999|ref|ZP_04712663.1| putative cytochrome P450 [Streptomyces roseosporus NRRL 11379] gi|291448986|ref|ZP_06588376.1| cytochrome P450 family protein [Streptomyces roseosporus NRRL 15998] gi|291351933|gb|EFE78837.1| cytochrome P450 family protein [Streptomyces roseosporus NRRL 15998] Length=455 Score = 169 bits (429), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 116/337 (35%), Positives = 168/337 (50%), Gaps = 6/337 (1%) Query 64 TALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSA 123 +IV+ G D RR+RS+V P +R V Y ATM ++ + D W GQR+D+ +E+ + Sbjct 96 NGMIVARGRDWRRKRSLVQPSVRPKQVTSYAATMAASAVELADRWSDGQRVDVKREMSAL 155 Query 124 VRRSTAESLFGQRLAVHSDFLGEQLQ-PLLDLTRRPPQV-MRLQQRVNSPGWRRAMAARK 181 ++ ++FG S+ +G + +++ + + L V +PG R A Sbjct 156 TQQIAVRTIFGVDTPADSEAMGRAMDVAQMEIGKEFAGIGALLPDWVPTPGRARIKKAAA 215 Query 182 RIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSG 241 ID + +A R +L+ L++ E GT L+D+EIRD V+L G+ETTS Sbjct 216 VIDAEVGRVVARHRDGEEERPDLLSRLLTAVDESGTHLTDDEIRDETVTLYIGGHETTST 275 Query 242 ALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVIS 301 L WA Y L P ++ A E+ RVLG R P +D + LTY VV ETLRLY P V Sbjct 276 TLVWAWYLLARNPRVRDALAEELDRVLGDREPGFEDYAQLTYTQAVVKETLRLY-PAVWL 334 Query 302 ARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPH 360 V ++ G I G + S + T R +PEP EFRP RWD D + A + Sbjct 335 ITGVAKEGATIGGLPIEEGTRVWSSQWATQRDARWFPEPEEFRPERWDAEHGD--EIAEY 392 Query 361 EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQL 397 + PF GG CIG A E ++LA L R L + Sbjct 393 AWFPFGGGPRVCIGTRFAMVEAVLLLAVLARRFTLDV 429 >gi|297156019|gb|ADI05731.1| cytochrome P450 family protein [Streptomyces bingchenggensis BCW-1] Length=486 Score = 169 bits (427), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 108/366 (30%), Positives = 180/366 (50%), Gaps = 24/366 (6%) Query 65 ALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQR----LDIYQEL 120 LI S+G +R+R + P + + M ++D W+ R +D+ ++ Sbjct 87 GLICSEGELWKRQRRLCQPAFHRRLITSFATGMTEVTAELLDRWEAAARAHREVDVTLDM 146 Query 121 RSAVRRSTAESLFGQRLAVHSDFLGEQLQPLL-DLTRRPPQVMRLQQRVNSPGWRRAMAA 179 +LFG S+ + ++ + + ++ + + L + V +P R A Sbjct 147 TRLALSVLGGALFGANWRQDSEVMAHAVEVAIGEAYKKFGKFVSLPEGVPTPANLRFARA 206 Query 180 RKRIDDLIDAQIADART--APRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYE 237 RK++D +I I D R P PDD +L L++ ++G+ ++ ++R+ +++ + G+E Sbjct 207 RKQLDRIIYRVIEDRRADRGPHPDD-LLEALMTATEDDGSGMTVEQVRNEVMTFMFGGHE 265 Query 238 TTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSP 297 T + L WA+Y L P +EV VLGGR+P +DL L Y++ VV E+LRLY P Sbjct 266 TVASGLTWALYLLSRHPEVAARLEAEVDEVLGGRLPGVEDLPRLPYVDRVVRESLRLYPP 325 Query 298 GVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKP 357 + +R L D G+ I G +++ S++VTHR P+ WP P F P RW P + Sbjct 326 VSLISRTPLEDDTVQGYDIPKGSMVLLSSFVTHRHPDFWPNPEGFDPDRWIPLG----EQ 381 Query 358 APHEFI--PFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRP 415 PH + PFSGG +CIG V EM ++LA + R R+R A + P Sbjct 382 GPHRYAWWPFSGGPRKCIGDVFGLQEMKLVLAMMAQRV----------RVRLAPGHPVIP 431 Query 416 WPGLTV 421 PG+T+ Sbjct 432 RPGITL 437 >gi|313116936|ref|YP_004038060.1| cytochrome P450 [Halogeometricum borinquense DSM 11551] gi|312294888|gb|ADQ68924.1| cytochrome P450 [Halogeometricum borinquense DSM 11551] Length=449 Score = 169 bits (427), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 104/361 (29%), Positives = 181/361 (51%), Gaps = 12/361 (3%) Query 38 NRFVFANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATM 97 N + DAF +L P+ G + ++ S+GA RR R ++ P + ++ Y M Sbjct 73 NNQNYVKGDAFQ-----STLGPITG-SGILNSEGAIWRRNRHLIQPAFHPNRIEEYSEMM 126 Query 98 VSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRR 157 + +++ W G+ +I++++ + + + +LFG + H + +GE L+ ++ + Sbjct 127 TGYTEEMLETWSDGETREIHEDMMTVTLKIVSRALFGVDIDDHVEDIGEALESFMEASES 186 Query 158 PPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGT 217 + L + + +P ++ AR+++DD++ I D R P D +++ L+ ++G Sbjct 187 LSHYV-LPEEIPTPSRKQIQGAREQLDDVVYELIEDRRANPGEQD-VISMLLDVTDDDGN 244 Query 218 TLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADD 277 TLS +IRD +V+L+ AG+ETT+ +L++ YAL P E+ VL GR P D Sbjct 245 TLSTEQIRDEVVTLLLAGHETTALSLSFTAYALARHPEAEAKLVEELDEVLDGRTPTMSD 304 Query 278 LSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWP 337 LS LTY VV E++RLY P R ++ G+ I AG + +V HR + Sbjct 305 LSELTYTEQVVKESMRLYPPVPGIVREPVKPDIIGGYEIPAGATVRMHQWVVHRDERWYD 364 Query 338 EPTEFRPLRWDPNAADYRKPAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQ 396 +P F P RW D + P + PF+ G RCIG A E ++LA + + L+ Sbjct 365 DPLAFEPERW---TDDLEQSIPKLAYFPFAAGPRRCIGDRFAMLEARLLLATIYQKYHLE 421 Query 397 L 397 L Sbjct 422 L 422 >gi|218245968|ref|YP_002371339.1| cytochrome P450 [Cyanothece sp. PCC 8801] gi|257059016|ref|YP_003136904.1| cytochrome P450 [Cyanothece sp. PCC 8802] gi|218166446|gb|ACK65183.1| cytochrome P450 [Cyanothece sp. PCC 8801] gi|256589182|gb|ACV00069.1| cytochrome P450 [Cyanothece sp. PCC 8802] Length=473 Score = 168 bits (425), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 114/371 (31%), Positives = 189/371 (51%), Gaps = 15/371 (4%) Query 49 SWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGW 108 S SQ + L P+ G + I+ DG HR+RR +V P ++ Y V V++ Sbjct 69 SPSQYNQLLQPLVGDNSTIMIDGDRHRKRRQLVMPSFHGERLKTYGELTVRITKEVLNQL 128 Query 109 QPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVM-----R 163 GQ ++S + E++FG + L L L DL P Sbjct 129 PTGQPFLGRPTMQSISLKVIMEAVFGITQGERYEKLQRLLGQLTDLFESPVTSALLFFPS 188 Query 164 LQQRVNS-PGWRRAMAARKRIDDLIDAQIADARTAPRPD-DHMLTTLISGCSEEGTTLSD 221 LQ+ S W + + R++ID+LI A+I+D R+ P+ +L+ LI E G LSD Sbjct 189 LQKDWGSWSPWGKFLRQRQQIDELIYAEISDRRSHQDPNRTDILSLLIEARDEAGEPLSD 248 Query 222 NEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSAL 281 E+RD +++L+ AG+ETT+ A+ W +Y L P E E+ + G P A ++ L Sbjct 249 QELRDELMTLLIAGHETTATAMTWGLYWLHRTPEVKEKLYQELTSL--GESPDAMEIFRL 306 Query 282 TYLNGVVHETLRLYSPGVISARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPT 340 YL V +ETLR+ +++ RV + + G++I G L++ Y+T + +++P P Sbjct 307 PYLTAVCNETLRISPVTMLTFPRVAEEPIELLGYKIEPGTLIMGCMYLTMQREDLYPNPR 366 Query 341 EFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQ 400 EFRP R+ R+ +P+EF+PF GG+ RC+G +A EM ++LA ++A L+L + Sbjct 367 EFRPERFLE-----RQYSPYEFLPFGGGVRRCLGEALAQFEMKLVLATIIANYQLKLAEK 421 Query 401 RTHRIRAANFA 411 + +++ F Sbjct 422 QPEKLQRRGFT 432 >gi|158341212|ref|YP_001522424.1| cytochrome P450 family protein [Acaryochloris marina MBIC11017] gi|158311453|gb|ABW33064.1| cytochrome P450 family protein [Acaryochloris marina MBIC11017] Length=447 Score = 167 bits (423), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 110/377 (30%), Positives = 183/377 (49%), Gaps = 10/377 (2%) Query 47 AFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVID 106 +F ++ SL V G L++SDG RR R ++ P + Y + +V ++ Sbjct 76 SFIKDVSYRSLSKVLG-NGLVLSDGELWRRHRQLMTPAFSQERISAYASIVVEETSHLLK 134 Query 107 GWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPL-LDLTRRPPQVMRLQ 165 W+ G LDIYQE+R + A++LFG + + +G+ L+ + L + R L Sbjct 135 HWKKGGILDIYQEMRQLTVKVIAKALFGIDVTQTALEIGDALEAISLQIYHRAQTNFLLP 194 Query 166 QRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIR 225 + + RA A + ++ ++ + I +P+ D +L+TL+S E+G LS E+R Sbjct 195 DWMPTKSNLRANRAIQYLNKIVISIIEQRYQSPK--DDLLSTLLSVKDEDGNQLSFEELR 252 Query 226 DSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLN 285 D +++L+ AG++TT+ AL W I L P E L G++P L L Y Sbjct 253 DEVMTLLLAGHDTTANALTWTIMLLAQHPTVANQLRKETQTELDGKIPNITFLPRLAYSQ 312 Query 286 GVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPL 345 V+ E++RLYSP I R ++D +R++ G ++ S +V HR P + EP +F P Sbjct 313 KVIRESMRLYSPAWILTREAIQDCQIGPYRLKKGAGVVVSQWVVHRDPRFFEEPEKFLPE 372 Query 346 RWDPNAADYRKPAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHR 404 RW N + + P + PF G CIG + E T+ILA + + +L ++ Sbjct 373 RWQDN---FEQKLPRCTYFPFGAGPRVCIGKAFSMMEATLILAMIANQFHFKLVPDQS-- 427 Query 405 IRAANFAALRPWPGLTV 421 I LRP G+ + Sbjct 428 IELLPSITLRPKQGIKM 444 >gi|298250363|ref|ZP_06974167.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] gi|297548367|gb|EFH82234.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] Length=470 Score = 167 bits (422), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 125/424 (30%), Positives = 201/424 (48%), Gaps = 30/424 (7%) Query 12 LYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPVDGPTA------ 65 L+ G ++ G Y G + N V +N F S+ TA Sbjct 40 LHATYGDVVTLAQGTSTYVCAFGPDLNFQVLSNPQLFQAGGDV-SVTKFRQDTAFGKLMS 98 Query 66 --LIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSA 123 L+ DG HR+ R ++ P + Y M+S +++ W+ ++++++E++ Sbjct 99 QNLMQMDGEKHRQHRRLMQPAFHRQQIAAYHQDMMSLTQQLLESWREQTQINVHREMQDL 158 Query 124 VRRSTAESLFGQRLAVHSDFLGEQLQP----LLDLTRRPPQVMRLQQRVNSPGWRRAMAA 179 R ++LFG V+ + E+LQ L D+TR M L + + R + Sbjct 159 TLRIAVKTLFG----VYDE---EELQHVGTLLRDMTRSMLLTMALPYDIPGTPYHRVLRL 211 Query 180 RKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETT 239 + + + A IA R D +L+ LI EEG TLSD+E+ +L AG+ETT Sbjct 212 SEELTAFMRATIARKRAHNEEAD-VLSALIHAHDEEGATLSDDELIGHAFALFVAGHETT 270 Query 240 SGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGV 299 + AL+W + L P E+ L G VP + LS L+ L+GV+ E+LRL+ P Sbjct 271 ANALSWILLLLSQHPQVCAELLEELDGALQGSVPTLEQLSQLSLLDGVIKESLRLFPPAA 330 Query 300 ISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAP 359 I R G+ + G +++S ++THRLPE++ P F P RW A+ R +P Sbjct 331 IGIRIASEACDLGGYALPKGTNVVYSEFLTHRLPELYTNPDHFLPKRW---ASLTR--SP 385 Query 360 HEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGL 419 +E++PFS G H CIG AT EM V+LA L+ R L+ P + + ++RP PG+ Sbjct 386 YEYLPFSAGRHMCIGLSFATQEMKVVLAMLLQRYRLE-PVPNA---KISTQLSMRPVPGI 441 Query 420 TVEI 423 + + Sbjct 442 PMHV 445 >gi|257059251|ref|YP_003137139.1| cytochrome P450 [Cyanothece sp. PCC 8802] gi|256589417|gb|ACV00304.1| cytochrome P450 [Cyanothece sp. PCC 8802] Length=457 Score = 167 bits (422), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 106/366 (29%), Positives = 181/366 (50%), Gaps = 15/366 (4%) Query 43 ANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNID 102 AN D F + +L P+ G +++ DG H++RR ++ P +Q Y ++ D Sbjct 75 ANTDLFDSGASNAALKPLLGDMSILQLDGNPHQQRRKLLMPSFHGQRLQSYGKIIIEITD 134 Query 103 TVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVM 162 VI W+ Q + + + +++FG + D L ++ LDL P Sbjct 135 KVIKQWKINQPFLMRNVTQEITLKVILKAVFGVNEGEYYDQLRQKFSHYLDLFNSPIYTT 194 Query 163 RL-----QQRVNS-PGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEG 216 L Q+ + S W ++ I +L+ +I R +D +L+ L+S E+G Sbjct 195 TLFLNYLQKDLGSWSPWGHFQRQKQAIYELLSQEIETHRQQDGGED-ILSLLLSTTDEDG 253 Query 217 TTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAAD 276 LS EI D +V+L+ AG++TT+ ALAWA Y + + P + + +E+ + P Sbjct 254 NPLSKAEIMDELVTLLFAGHDTTASALAWAFYWIHSQPDVYHNLMNELGTIDAETDPT-- 311 Query 277 DLSALTYLNGVVHETLRLYSPGVISARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLPEI 335 +++ L YLN VV ETLR+Y + + R+L+ L F G+ G + Y+ H PE+ Sbjct 312 NIAKLPYLNAVVSETLRIYPIALFAFGRMLKSPLDFMGYSFDKGTIFSPCIYLVHHHPEV 371 Query 336 WPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAML 395 +P F+P R+ R+ +P+EFIPF G RC+G +A EM ++LA ++ + L Sbjct 372 YPNSKTFKPERFLE-----RQFSPYEFIPFGGSNRRCLGYALALYEMKLVLATVLQKTTL 426 Query 396 QLPAQR 401 +L + R Sbjct 427 KLASSR 432 >gi|288554506|ref|YP_003426441.1| cytochrome P450, hydroxylase or monooxygenase [Bacillus pseudofirmus OF4] gi|288545666|gb|ADC49549.1| cytochrome P450, hydroxylase or monooxygenase [Bacillus pseudofirmus OF4] Length=452 Score = 166 bits (420), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 100/386 (26%), Positives = 181/386 (47%), Gaps = 16/386 (4%) Query 47 AFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVID 106 AF S+ + L V G L+ ++ H ++R ++ P + H+ +Y M+ + I Sbjct 74 AFIKSRDIQMLKAVVG-EGLLTNEKESHLKQRRLIQPAFKKTHIHQYAQDMIETTNAFIK 132 Query 107 GWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQ 166 GW+ + +I ++ + +++FG + +D + + ++ ++ L + R++ Sbjct 133 GWKGEEERNIAADMMNIALGIITKTMFGMEMGQGADVIEQPMEAVMKLG-----IKRMRS 187 Query 167 RVNSPGW------RRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEE-GTTL 219 P W R+ A K +DD++ + I+ R + +L L+ EE G + Sbjct 188 LSPLPLWVPTQANRQLKKAVKELDDVLFSIISKRRLEDNQSEDLLGMLMKARDEENGAVM 247 Query 220 SDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLS 279 SD ++RD ++++ AG+ETT+ LAW +Y L P E +E+ V G + + Sbjct 248 SDQQLRDELMTIFLAGHETTANLLAWTLYLLSEHPSADERLYAEIKEVTNGEALLPEHYT 307 Query 280 ALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEP 339 LTY V+ E++RLY P + R+V D+ + G +++ S YV HR + EP Sbjct 308 KLTYTQNVISESMRLYPPAYVIGRQVEEDIEIGPYLFNKGAMVLISQYVMHRNASFYHEP 367 Query 340 TEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPA 399 F+P R+D N + P + PF GG CIG A E T+ LA + L + Sbjct 368 NIFKPERFDHNF--LKTLPPFAYFPFGGGPRVCIGNHFAMMEATLALAAIAQNYKFTLTS 425 Query 400 QRTHRIRAANFAALRPWPGLTVEIRK 425 + ++ LRP GL +++ K Sbjct 426 SQ-QKVTPQPLITLRPKGGLMMKVEK 450 >gi|291566629|dbj|BAI88901.1| cytochrome P450 [Arthrospira platensis NIES-39] Length=459 Score = 165 bits (418), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 109/364 (30%), Positives = 181/364 (50%), Gaps = 23/364 (6%) Query 45 ADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTV 104 AD + P+ GP +LI DG++H+R R ++ P L + RY + + D+V Sbjct 71 ADQLELGRITHVFEPLTGPQSLIAKDGSEHQRLRQLLMPPLHGKQLPRYGEAIANIADSV 130 Query 105 IDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDL----TRRPPQ 160 + W G + I R R + +++ L + +L QLQ L+ P Sbjct 131 TENWSVGDCISI----RKYTARMSLQTILQVVLGLGPGYLMNQLQQTLETYLEWVNSPLN 186 Query 161 VMR-----LQQRVNSPG-WRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSE 214 ++ LQ+ + + W + + R++IDDLI I D R +D +L+ LIS E Sbjct 187 SLQFFWPALQKDLGAASPWGKFLRQRQQIDDLIYTAIGDRRREATGED-VLSLLISARDE 245 Query 215 EGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPA 274 G +SD E+RD I++L+ GY+TT+ A AW Y + P + +E+ + PA Sbjct 246 NGEGMSDQELRDQIITLLLLGYDTTASATAWVFYWIHKFPHIRDQLVAELQTLGSDSDPA 305 Query 275 ADDLSALTYLNGVVHETLRLYSPGVISARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLP 333 + L YL V E LRL+ +IS RV+R+ + G R + G +L+ ++ HR Sbjct 306 --EAVQLPYLTAVCREALRLHPIALISQPRVVRESVTIGGDRFQPGTVLVPCIHLAHRRS 363 Query 334 EIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARA 393 + +PEP +FRP R+ R+ +P+E+ PF GG CIG ++ E+ +I+A +++R Sbjct 364 QTYPEPEKFRPERFLE-----RRFSPYEYFPFGGGSRSCIGMALSLFEIKIIVATVLSRC 418 Query 394 MLQL 397 L Sbjct 419 QFSL 422 >gi|284051209|ref|ZP_06381419.1| cytochrome P450 [Arthrospira platensis str. Paraca] Length=450 Score = 165 bits (418), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 109/364 (30%), Positives = 181/364 (50%), Gaps = 23/364 (6%) Query 45 ADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTV 104 AD + P+ GP +LI DG++H+R R ++ P L + RY + + D+V Sbjct 62 ADQLELGRITHVFEPLTGPQSLIAKDGSEHQRLRQLLMPPLHGKQLPRYGEAIANIADSV 121 Query 105 IDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDL----TRRPPQ 160 + W G + I R R + +++ L + +L QLQ L+ P Sbjct 122 TENWSVGDCISI----RKYTARMSLQTILQVVLGLGPGYLMNQLQQTLETYLEWVNSPLN 177 Query 161 VMR-----LQQRVNSPG-WRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSE 214 ++ LQ+ + + W + + R++IDDLI I D R +D +L+ LIS E Sbjct 178 SLQFFWPALQKDLGAASPWGKFLRQRQQIDDLIYTAIGDRRREATGED-VLSLLISARDE 236 Query 215 EGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPA 274 G +SD E+RD I++L+ GY+TT+ A AW Y + P + +E+ + PA Sbjct 237 NGEGMSDQELRDQIITLLLLGYDTTASATAWVFYWIHKFPHIRDQLVAELQTLGSDSDPA 296 Query 275 ADDLSALTYLNGVVHETLRLYSPGVISARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLP 333 + L YL V E LRL+ +IS RV+R+ + G R + G +L+ ++ HR Sbjct 297 --EAVQLPYLTAVCREALRLHPIALISQPRVVRESVTIGGDRFQPGTVLVPCIHLAHRRS 354 Query 334 EIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARA 393 + +PEP +FRP R+ R+ +P+E+ PF GG CIG ++ E+ +I+A +++R Sbjct 355 QTYPEPEKFRPERFLE-----RRFSPYEYFPFGGGSRSCIGMALSLFEIKIIVATVLSRC 409 Query 394 MLQL 397 L Sbjct 410 QFSL 413 >gi|254416793|ref|ZP_05030542.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] gi|196176339|gb|EDX71354.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] Length=458 Score = 164 bits (416), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 115/403 (29%), Positives = 197/403 (49%), Gaps = 35/403 (8%) Query 26 GHGYTYLLGAEANRFVF------------ANADAFSWSQTFESLV-PVDGPTALIVSDGA 72 G +T LG + VF ++ F S + L P+ G ++I G Sbjct 34 GDIFTVPLGKKFTPLVFVSNPQALQQILSSDTKEFDASGEYNELFEPMLGNQSVITLSGK 93 Query 73 DHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESL 132 HRR+R ++ P ++ Y + + V+ W+ G+ + ++ R +++ Sbjct 94 SHRRQRQLMMPPFHGERMKAYGELIAEITEQVLHQWEVGKSFSVRSFMQQISLRVILQAV 153 Query 133 FGQRLAVHSDFLGEQLQPLLDLTRRPPQV-------MRLQQRVNSPGWRRAMAARKRIDD 185 FG L + L +LD + P +V +R SP W R + R++ID Sbjct 154 FGLYEGERYHKLEQLLSMMLDQSSTPGRVSALYFPILRQDLGAWSP-WGRFLRQRQQIDQ 212 Query 186 LIDAQIADARTAPRPDDH---MLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGA 242 LI +I + R +PDD +L+ L+S E G ++D E+RD +++L+ AG+ETT+ A Sbjct 213 LIYDEINERRD--QPDDSRTDILSMLMSARDEAGQPMTDTELRDELMTLLVAGHETTATA 270 Query 243 LAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISA 302 LAWA+Y + +P + E+ + P L L YLN V ETLR+Y G+++ Sbjct 271 LAWALYWIHKLPEVRQKLLEELDSLDN---PDPSTLFRLPYLNAVCSETLRIYPVGMLTF 327 Query 303 RRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHE 361 RV+R + G+++ +L+ Y+TH+ +++PEP +F+P R+ + P+E Sbjct 328 PRVVRSPVELMGYQLEPDTVLVGCIYLTHQRQDLYPEPKQFKPERFLEHHF-----YPYE 382 Query 362 FIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHR 404 ++PF GG RCIG A EM ++LA++++ L L R R Sbjct 383 YLPFGGGARRCIGMAFAQFEMKIVLAKILSSCELALANNRPVR 425 >gi|337749462|ref|YP_004643624.1| cytochrome P450 hydroxylase [Paenibacillus mucilaginosus KNP414] gi|336300651|gb|AEI43754.1| cytochrome P450 hydroxylase [Paenibacillus mucilaginosus KNP414] Length=464 Score = 164 bits (416), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 113/379 (30%), Positives = 187/379 (50%), Gaps = 18/379 (4%) Query 64 TALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSA 123 L+ S+G+ R+R + P HH ++ Y M + ++ W+ + DI+ ++ Sbjct 88 NGLVTSEGSFWLRQRRLSQPAFHHHRIRSYADIMTAYAQRMLAAWEHEESRDIHADMMQC 147 Query 124 VRRSTAESLFGQRLAVH---SDFLGEQLQPLL-DLTRRPPQVMR-----LQQRVNSPGWR 174 A++LF L S+ +GE L + + ++ VMR L V PG + Sbjct 148 TMEIVAKTLFDVDLHAEDGRSNPVGEALDAVFHEYVKQYTSVMRRLLDLLPVSVPVPGDK 207 Query 175 RAMAARKRIDDLIDAQIADARTAPRPDDH--MLTTLISGCSEEGTTLSDNEIRDSIVSLI 232 + + ++++ +I I D R A +D +L+ L+ E+GT ++ ++RD I++L Sbjct 208 KLQESVEQLNRII-LDIIDRRQAEGTEDRGDLLSMLLLARDEDGTGMTREQLRDEIMTLF 266 Query 233 TAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETL 292 AG+ETT+ L+W +Y L P E+ RVLGG+ PA + + LTY VV E++ Sbjct 267 LAGHETTANVLSWTLYLLAREPEAEGKLLKELDRVLGGQPPAFEHIPLLTYTQSVVKESM 326 Query 293 RLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAA 352 RLY P + +R + D+ G+ + AG + +V HRLPE + EP F+P RW P Sbjct 327 RLYPPVWLISREPIEDVEIGGYTLPAGCEISVCQWVMHRLPEYFEEPERFQPERWTP--- 383 Query 353 DYRKPAPHE-FIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFA 411 ++ K P +IPF G CIG A E ++LA + R L L + H++ Sbjct 384 EFEKSLPAGVYIPFGAGPRVCIGNQFAMMEAVLLLASIGQRFRLTL--EPGHKVLLEPSI 441 Query 412 ALRPWPGLTVEIRKSAPAQ 430 LRP G+ V + K + Q Sbjct 442 TLRPQTGIRVRVWKRSAEQ 460 >gi|162453161|ref|YP_001615528.1| cytochrome P450 CYP263A1 [Sorangium cellulosum 'So ce 56'] gi|161163743|emb|CAN95048.1| Cytochrome P450 CYP263A1 [Sorangium cellulosum 'So ce 56'] Length=493 Score = 164 bits (414), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 119/401 (30%), Positives = 193/401 (49%), Gaps = 30/401 (7%) Query 44 NADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDT 103 NA + + + L PV G L+ S+G RR+R V P H + ++V +V +++ Sbjct 69 NARNYPKGKRYHELAPVLG-WGLVNSEGELWRRQRRHVQPQFNHANTLKFVPIIVEHMEA 127 Query 104 VIDGW--QPGQ-RLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQ 160 V+ W QPG+ DI ++ E+ FG L H+D + E + L + Sbjct 128 VLRRWDAQPGEFERDINDDMMDVTFGIAGEAFFGAALHAHTDTVREAFKYALSIA----- 182 Query 161 VMRLQQRVNSP---------GWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISG 211 + R+ VN P +RRAM R+ +ID I + +D++L L++ Sbjct 183 LKRMYSLVNPPLSWPLPSHLRFRRAM---DRVHAVIDGIIDGYQRGAGGEDNVLVRLMNS 239 Query 212 CS-EEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGG 270 E G + ++RD I +++ G+ET+S +WA+Y L P E+ RVLGG Sbjct 240 VDPETGAKMDRAQLRDEIKTILMVGHETSSVTASWALYQLARHPEVCARLTDEIDRVLGG 299 Query 271 RVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTH 330 R P A D+ ++ YL V +E LRL R L D G+++ AG + +VTH Sbjct 300 RSPTARDIESMPYLTMVFNECLRLLPSVPFILRSPLEDDVIGGYKVAAGSTVAIVPWVTH 359 Query 331 RLPEIWPEPTEFRPLRWDPNAADYRKPAPHE--FIPFSGGLHRCIGAVMATTEMTVILAR 388 R PE W +P EF+P R+ A++R+ A + FIPF G C+G M E +++A Sbjct 360 RHPEFWSDPLEFKPERF----ANHRRSADDKLAFIPFGAGQRICLGEFMGQLEGKIMVAM 415 Query 389 LVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIRKSAPA 429 + R L+L R R F +L+P G+ + +++ P+ Sbjct 416 ALQRYRLRLVPGFDPRCRG--FISLQPVNGMRMILKRREPS 454 >gi|338739348|ref|YP_004676310.1| Cytochrome P450 family protein [Hyphomicrobium sp. MC1] gi|337759911|emb|CCB65742.1| Cytochrome P450 family protein [Hyphomicrobium sp. MC1] Length=454 Score = 164 bits (414), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 113/347 (33%), Positives = 171/347 (50%), Gaps = 11/347 (3%) Query 46 DAFSWSQTF--ESLVPVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDT 103 DA S+ + F + PV G L+ S+G +R ++ P V Y M + Sbjct 77 DARSYIKHFGARTFKPVLG-NGLVTSEGDFWLTQRRLLQPAFLKTQVLSYAPVMAELTEA 135 Query 104 VIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFL--GEQLQPLLDL-TRRPPQ 160 ++ W PG +DI E + ++LFG L H D + E L+ +L T R Sbjct 136 MLAKWVPGTSVDIAFEFSALTSAIALKTLFG--LDDHGDRVRVDESLRLTFELLTHRLDS 193 Query 161 VMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLS 220 + ++ +P R A ++ +ID IA + A P + +L+T+I+ E+GT ++ Sbjct 194 LFQVPLVFPTPANLRLKRAIADVNAVIDGFIAQ-KQAASPGNDLLSTMIAAQREDGTQMT 252 Query 221 DNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSA 280 ++RD ++L AG+ETT+ L W+ Y L P + +E RVLGGR A DLSA Sbjct 253 AQQLRDEAMTLYLAGHETTALTLTWSWYLLSQHPDVEQKLVAEWQRVLGGRAARASDLSA 312 Query 281 LTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPT 340 LTY V++E +RLY P + R DL G+R++ G ++ S +V HR P+ +PEP Sbjct 313 LTYTAAVINEAMRLYPPVYVIGREATTDLELGGYRVKKGYTILMSQWVNHRDPKYFPEPE 372 Query 341 EFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILA 387 F P RW A R P + PF GG CIG A E ++LA Sbjct 373 RFLPERWLDGLAS-RLPK-FAYYPFGGGQRLCIGVHFALMEAAIVLA 417 >gi|294628910|ref|ZP_06707470.1| cytochrome P450 family protein [Streptomyces sp. e14] gi|292832243|gb|EFF90592.1| cytochrome P450 family protein [Streptomyces sp. e14] Length=452 Score = 163 bits (413), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 115/398 (29%), Positives = 186/398 (47%), Gaps = 16/398 (4%) Query 2 RYPLGEALLALYRWRGPLINAGVGGHGYTYLLGAEANRFVFANADAFSWSQTFESLVPVD 61 RYPL LA G L+ +G + E R V N + F+ + Sbjct 33 RYPL--EFLASLPAHGDLVELRLGPNRAYLAAHPELVREVLLNPRVYDKGGVFDKARQLL 90 Query 62 GPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELR 121 G +L VS G +HR +R ++ P R + Y + ++ V D W+ G+ DI + Sbjct 91 G-NSLSVSRGEEHRFQRRLIQPAFRPAKIAAYTTAVAADTRRVTDSWRSGETQDISDTMH 149 Query 122 SAVRRSTAESLFGQRLAVHSDFLGEQLQPLL-----DLTRRPPQVMRLQQRVNSPGWRRA 176 + + R A +LF L D L E+ + L + +R + + +++ +P R Sbjct 150 ALLMRVAARTLFSAGL---DDALIEEARRCLRTVSHGIYKRTMAPLGIMEKLPTPANRAY 206 Query 177 MAARKRIDDLIDAQIAD-ARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAG 235 A R+ ++ IA R+ +D + T L + E G L D ++ D +++ + AG Sbjct 207 ARANGRLRQIVADMIARRGRSETGQEDLLATLLQAEHPETGEKLDDRQVLDQVITFLVAG 266 Query 236 YETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLY 295 ETT+ LA+ + + T+P + +EV L R P DDL L Y V+ E LRLY Sbjct 267 SETTASTLAFVFHLMGTLPEVEKQVHAEVDEALRDRTPGYDDLPGLPYTRNVITEALRLY 326 Query 296 SPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYR 355 P ++ R +D+ G + AG ++++SAY H P ++P+P F P RW+ D Sbjct 327 PPSWMAMRVTTQDVGLGGRTVPAGTMILYSAYALHHNPALFPDPEHFDPGRWE---GDRL 383 Query 356 KPAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVAR 392 P +PF G H+CIG V+A TE +I+A + AR Sbjct 384 AQVPRGALLPFGAGTHKCIGDVLALTETALIVATVAAR 421 >gi|113477166|ref|YP_723227.1| cytochrome P450 [Trichodesmium erythraeum IMS101] gi|110168214|gb|ABG52754.1| cytochrome P450 [Trichodesmium erythraeum IMS101] Length=462 Score = 163 bits (413), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 116/396 (30%), Positives = 202/396 (52%), Gaps = 29/396 (7%) Query 27 HGYTYLLGAEANRFVF-ANADAFSWSQTFESLVPVDGPTALIVSDGADHRRRRSVVAPGL 85 + + Y +A + +F A+ D F+ L G +L++ DG H+R+R ++ P Sbjct 48 YPFIYFCNPKAIQQIFTADPDTFTSGSINGILKYFVGLNSLLLQDGDRHKRQRKLLMPPF 107 Query 86 RHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFG--------QRL 137 +++Y + + VI W+ Q I + + + ++FG ++L Sbjct 108 HGDRMRKYGDLIYNITSNVISQWKIEQPFPIRKSTQEISLKVILAAVFGLDQEGKSYEKL 167 Query 138 AV-HSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADART 196 V SD L PL T +R SP W R + ++ + +LI A+I A+ Sbjct 168 RVLMSDLLDSMSSPLSS-TFLFFNFLRKDWGPWSP-WGRFLRKKQELHELIIAEIQTAKK 225 Query 197 APRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGT 256 D +L+ L+ E G +SD EI+D +++++ AG+ETT+ ALAWA+Y + +P Sbjct 226 EGNHRDDILSLLLEARDEAGNAMSDEEIKDELLTMLFAGHETTASALAWALYWIDMIPSV 285 Query 257 WESAASEVARVLGGRVPAADDLSALT---YLNGVVHETLRLYSPGVISA--RRVLRDLWF 311 E +E+A +P+ D A+T YL+ + ETLR+Y P ++A R V + + Sbjct 286 GEKLMAELA-----TIPSNSDQVAITKLPYLSAICQETLRIY-PIAMNAFPRVVQKPIEI 339 Query 312 DGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHR 371 G+++ G + I Y+TH +I+PEP +F+P R+ R+ +P+E++PF GG R Sbjct 340 MGYQLEPGMVAIVPIYLTHHREDIYPEPKKFKPERFLE-----RQFSPYEYLPFGGGSRR 394 Query 372 CIGAVMATTEMTVILARLVARAMLQ-LPAQRTHRIR 406 CIG+ A EM ++LA ++++ L+ LP QR +R Sbjct 395 CIGSAFALFEMKLVLATILSQWELKLLPNQRISPVR 430 >gi|322371142|ref|ZP_08045694.1| cytochrome P450 [Haladaptatus paucihalophilus DX253] gi|320549132|gb|EFW90794.1| cytochrome P450 [Haladaptatus paucihalophilus DX253] Length=450 Score = 162 bits (411), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 102/362 (29%), Positives = 178/362 (50%), Gaps = 8/362 (2%) Query 38 NRFVFANADAFSWSQTFESLV-PVDGPTALIVSDGADHRRRRSVVAPGLRHHHVQRYVAT 96 + + N + + F+ ++ PV G ++ S+GA RR R ++ P +QRY Sbjct 66 EQVLVQNNQNYIKGEGFQHILGPVLG-NGILNSEGAVWRRNRHLIQPAFHPKEIQRYSEM 124 Query 97 MVSNIDTVIDGWQPGQRLDIYQELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTR 156 M + ++ W+ G+ +++++ + A +LFG + D +G L+ + T Sbjct 125 MTDFTEEALETWEDGETRLVHEDMMEVTLKIVARALFGVDIEDEVDTIGSALEEFMLGTE 184 Query 157 RPPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEG 216 + L ++ +P R AR+++D ++ I + R P + +++TL+S E Sbjct 185 NLANFI-LPPKIPTPSRMRIKDAREKLDGVVYRMIRERRNDPD-GEGVISTLLSATDEHE 242 Query 217 TTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAAD 276 +SD +IRD +V+L+ AG+ETT+ +L +YAL P +E+ VL G P + Sbjct 243 NPMSDEQIRDEVVTLLLAGHETTALSLTLTMYALAQYPEVETKLVAELDEVLDGETPTME 302 Query 277 DLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIW 336 D+S LTY VV E++RLY P R + G+ I AG + + +V HR P + Sbjct 303 DVSELTYTEQVVKESMRLYPPVPGIVREATKPDIIGGYEIPAGATVQMNQWVVHRDPRWY 362 Query 337 PEPTEFRPLRWDPNAADYRKPAPH-EFIPFSGGLHRCIGAVMATTEMTVILARLVARAML 395 +P FRP RW ++ K P + PF+ G RCIG A E ++LA + + + Sbjct 363 DDPLAFRPERW---TDEFEKSLPKLAYFPFAAGPRRCIGDRFAMLEARLLLATIYQQFHI 419 Query 396 QL 397 +L Sbjct 420 EL 421 >gi|298250792|ref|ZP_06974596.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] gi|297548796|gb|EFH82663.1| cytochrome P450 [Ktedonobacter racemifer DSM 44963] Length=453 Score = 162 bits (410), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 107/367 (30%), Positives = 175/367 (48%), Gaps = 14/367 (3%) Query 65 ALIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQPGQRLDIYQELRSAV 124 L+ ++G HR++R +V P + +Y MV + +++ WQPGQ L++ ++ Sbjct 88 GLLTTEGEIHRQQRRLVQPAFHRQRIDQYADVMVRYTEQMLETWQPGQELELASAMQHLT 147 Query 125 RRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVM---RLQQRVNSPGWRRAMAARK 181 R +LF ++ L E ++ RPPQ + R+ R ++ R +K Sbjct 148 LRIIVHTLFSVEELSQANQLSEAFTAVIG---RPPQGLGRPRVLSRFSAQT-RDFNRGKK 203 Query 182 RIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTLSDNEIRDSIVSLITAGYETTSG 241 +DD + I R +L L++ EEG +SD+++ D +++L+ AG+ETT Sbjct 204 TLDDFVYGLIQQRRATGGDRGDILDMLLTA-QEEGQGMSDSQVHDQVMTLVAAGHETTQN 262 Query 242 ALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVIS 301 +L W Y L P + E+ VL G P DL+ L YL V++E+ R+ P Sbjct 263 SLCWTFYLLAQHPEIRQKLLLELHTVLVGHTPTVADLARLPYLEWVMNESWRVLPPVWRM 322 Query 302 ARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRPLRWDPNAADYRKPAPHE 361 RR + D + + AG +++ S +VTH EIW +P EFRP RWDP + K Sbjct 323 GRRAIHDFTLGDYHLPAGTIVLLSQWVTHNDTEIWHDPQEFRPERWDPIQGE--KVPRGA 380 Query 362 FIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQ-LPAQRTHRIRAANFAALRPWPGLT 420 + PF G CIG A E ++LA ++ R + +P H I LRP G+ Sbjct 381 YFPFGLGPRICIGMPFAQMETKLLLATILQRYTPEPVP---DHPIELLPSVTLRPKHGMR 437 Query 421 VEIRKSA 427 V + ++ Sbjct 438 VTLNPTS 444 Lambda K H 0.322 0.136 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 880492674816 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40