BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1692 Length=353 Score E Sequences producing significant alignments: (Bits) Value gi|15608830|ref|NP_216208.1| phosphatase [Mycobacterium tubercul... 702 0.0 gi|289753782|ref|ZP_06513160.1| phosphatase [Mycobacterium tuber... 699 0.0 gi|289750248|ref|ZP_06509626.1| phosphatase [Mycobacterium tuber... 578 3e-163 gi|240170141|ref|ZP_04748800.1| phosphatase [Mycobacterium kansa... 471 6e-131 gi|183982512|ref|YP_001850803.1| phosphatase [Mycobacterium mari... 468 5e-130 gi|254775531|ref|ZP_05217047.1| HAD-superfamily protein hydrolas... 468 9e-130 gi|118617309|ref|YP_905641.1| phosphatase [Mycobacterium ulceran... 467 1e-129 gi|41407497|ref|NP_960333.1| hypothetical protein MAP1399 [Mycob... 462 3e-128 gi|296164592|ref|ZP_06847159.1| hydrolase [Mycobacterium parascr... 462 3e-128 gi|118466906|ref|YP_882263.1| HAD-superfamily protein hydrolase,... 462 5e-128 gi|336457851|gb|EGO36845.1| putative sugar phosphatase of HAD su... 461 8e-128 gi|342860730|ref|ZP_08717380.1| HAD-superfamily protein hydrolas... 437 9e-121 gi|333990488|ref|YP_004523102.1| phosphatase [Mycobacterium sp. ... 402 3e-110 gi|120404267|ref|YP_954096.1| HAD family hydrolase [Mycobacteriu... 402 5e-110 gi|118469538|ref|YP_888050.1| hydrolase [Mycobacterium smegmatis... 387 2e-105 gi|145224095|ref|YP_001134773.1| HAD family hydrolase [Mycobacte... 380 1e-103 gi|289569740|ref|ZP_06449967.1| predicted protein [Mycobacterium... 370 2e-100 gi|108799919|ref|YP_640116.1| HAD family hydrolase [Mycobacteriu... 360 2e-97 gi|126435547|ref|YP_001071238.1| HAD family hydrolase [Mycobacte... 356 3e-96 gi|169629443|ref|YP_001703092.1| HAD-superfamily hydrolase [Myco... 326 4e-87 gi|262202729|ref|YP_003273937.1| HAD-superfamily hydrolase [Gord... 312 4e-83 gi|333919191|ref|YP_004492772.1| phosphatase [Amycolicicoccus su... 303 3e-80 gi|343928396|ref|ZP_08767844.1| hypothetical protein GOALK_117_0... 298 8e-79 gi|325674264|ref|ZP_08153953.1| hydrolase [Rhodococcus equi ATCC... 297 2e-78 gi|312139858|ref|YP_004007194.1| haloacid dehalogenase-like hydr... 296 4e-78 gi|226360085|ref|YP_002777863.1| hydrolase [Rhodococcus opacus B... 293 3e-77 gi|226306755|ref|YP_002766715.1| hypothetical protein RER_32680 ... 286 3e-75 gi|229494827|ref|ZP_04388581.1| HAD-superfamily hydrolase, subfa... 286 5e-75 gi|111017954|ref|YP_700926.1| phosphatase [Rhodococcus jostii RH... 284 1e-74 gi|326384770|ref|ZP_08206447.1| HAD-superfamily hydrolase [Gordo... 270 3e-70 gi|302528027|ref|ZP_07280369.1| HAD-superfamily hydrolase [Strep... 268 1e-69 gi|257056538|ref|YP_003134370.1| putative sugar phosphatase of H... 263 3e-68 gi|331697606|ref|YP_004333845.1| HAD-superfamily hydrolase [Pseu... 262 5e-68 gi|296393971|ref|YP_003658855.1| HAD-superfamily hydrolase, subf... 262 6e-68 gi|300787882|ref|YP_003768173.1| HAD family hydrolase [Amycolato... 260 3e-67 gi|291003071|ref|ZP_06561044.1| HAD family hydrolase [Saccharopo... 253 4e-65 gi|134101756|ref|YP_001107417.1| HAD family hydrolase [Saccharop... 253 4e-65 gi|258654199|ref|YP_003203355.1| Haloacid dehalogenase domain-co... 252 5e-65 gi|319949195|ref|ZP_08023284.1| putative hydrolase [Dietzia cinn... 250 2e-64 gi|324998564|ref|ZP_08119676.1| predicted sugar phosphatase of H... 250 2e-64 gi|54023962|ref|YP_118204.1| putative hydrolase [Nocardia farcin... 249 6e-64 gi|254822055|ref|ZP_05227056.1| HAD-superfamily protein hydrolas... 238 8e-61 gi|256832354|ref|YP_003161081.1| HAD-superfamily hydrolase, subf... 237 3e-60 gi|317507357|ref|ZP_07965093.1| HAD-superfamily hydrolase [Segni... 234 2e-59 gi|257068536|ref|YP_003154791.1| putative sugar phosphatase of H... 234 2e-59 gi|271967341|ref|YP_003341537.1| sugar phosphatase of the HAD su... 234 2e-59 gi|334336861|ref|YP_004542013.1| HAD-superfamily hydrolase, subf... 233 5e-59 gi|296140087|ref|YP_003647330.1| HAD-superfamily hydrolase [Tsuk... 232 8e-59 gi|237785440|ref|YP_002906145.1| hypothetical protein ckrop_0848... 230 2e-58 gi|315506774|ref|YP_004085661.1| HAD superfamily hydrolase [Micr... 226 4e-57 >gi|15608830|ref|NP_216208.1| phosphatase [Mycobacterium tuberculosis H37Rv] gi|15841149|ref|NP_336186.1| hypothetical protein MT1731 [Mycobacterium tuberculosis CDC1551] gi|31792878|ref|NP_855371.1| phosphatase [Mycobacterium bovis AF2122/97] 74 more sequence titles Length=353 Score = 702 bits (1812), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/353 (100%), Positives = 353/353 (100%), Gaps = 0/353 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE Sbjct 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA Sbjct 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD Sbjct 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY Sbjct 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS Sbjct 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ 353 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ Sbjct 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ 353 >gi|289753782|ref|ZP_06513160.1| phosphatase [Mycobacterium tuberculosis EAS054] gi|289694369|gb|EFD61798.1| phosphatase [Mycobacterium tuberculosis EAS054] Length=353 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/353 (99%), Positives = 352/353 (99%), Gaps = 0/353 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE Sbjct 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALA EVAAVGLRPVRRFEDRPDA Sbjct 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALAYEVAAVGLRPVRRFEDRPDA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD Sbjct 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY Sbjct 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS Sbjct 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ 353 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ Sbjct 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ 353 >gi|289750248|ref|ZP_06509626.1| phosphatase [Mycobacterium tuberculosis T92] gi|289690835|gb|EFD58264.1| phosphatase [Mycobacterium tuberculosis T92] Length=292 Score = 578 bits (1491), Expect = 3e-163, Method: Compositional matrix adjust. Identities = 291/292 (99%), Positives = 291/292 (99%), Gaps = 0/292 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE Sbjct 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA Sbjct 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD Sbjct 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY Sbjct 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDL 292 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDV DL Sbjct 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVVDL 292 >gi|240170141|ref|ZP_04748800.1| phosphatase [Mycobacterium kansasii ATCC 12478] Length=336 Score = 471 bits (1213), Expect = 6e-131, Method: Compositional matrix adjust. Identities = 253/344 (74%), Positives = 284/344 (83%), Gaps = 8/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MKS+AQ++DCLLIDLDGTVF GR+ T GAVQSL+ V SRKLFVTNNASRSADEVAAHL E Sbjct 1 MKSLAQQYDCLLIDLDGTVFRGRRATEGAVQSLAGVSSRKLFVTNNASRSADEVAAHLRE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF A G DVVTSAQSAA +LA QL PG+ VLIVGT+ALA EVA VGL PVRR++D P A Sbjct 61 LGFDAYGNDVVTSAQSAARVLADQLPPGSPVLIVGTDALAAEVATVGLHPVRRWDDGPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMTTGW +LAEAALAIRAGALWVAANVDPTLPTERGLLPGNGS+VAALR ATG + Sbjct 121 VVQGLSMTTGWPELAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSLVAALRAATGAE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKP P LM +A+ARGD+RA LV+GDRLDTDIEGA+AAGLPSLMVL+GVNSA DAV+ Sbjct 181 PQVAGKPGPQLMADAIARGDWRAPLVIGDRLDTDIEGAHAAGLPSLMVLSGVNSARDAVF 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A P +RPTY+GHDLR LHQD +LLA+ QPGW++DV VTV A GD D D LS Sbjct 241 APPRQRPTYLGHDLRCLHQDGELLAIGSQPGWRVDVADTTVTVSATGDQD-----GDDLS 295 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 +VRAVASAVW+A RP+ I AGDE AR AL+RWSL D Sbjct 296 VVRAVASAVWDAHP---DGRPVSIGAGDEAARDALRRWSLEHGD 336 >gi|183982512|ref|YP_001850803.1| phosphatase [Mycobacterium marinum M] gi|183175838|gb|ACC40948.1| phosphatase [Mycobacterium marinum M] Length=336 Score = 468 bits (1205), Expect = 5e-130, Method: Compositional matrix adjust. Identities = 254/344 (74%), Positives = 284/344 (83%), Gaps = 8/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MK+IAQE+DCLLIDLDGTVF G QPT GAV+SL +V +RKLFVTNNASRSA EVA HL E Sbjct 1 MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTARKLFVTNNASRSAGEVAVHLRE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT EDVVTSAQSAAHLLA L PG++VL+VGT+ALA+E++A GLRPVRRFED+PDA Sbjct 61 LGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGTDALADEISAAGLRPVRRFEDQPDA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLS+T GW +LAEAALAIRAGALWVAANVD TLPTERGLLPGNGS+VAALRTATG Sbjct 121 VVQGLSLTIGWPELAEAALAIRAGALWVAANVDKTLPTERGLLPGNGSLVAALRTATGAQ 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKP P LM +AV RGDFRA LV+GDRLDTDIEGANAAGLPSLMVLTGV+SA DAV+ Sbjct 181 PQVAGKPGPQLMKDAVGRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVH 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+PV RPTYIGHDLRSL QD LAVAPQ GW++ V G AVTV ANG E D LS Sbjct 241 ADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVDGAAVTVSANG-----EQAGDDLS 295 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 IVRAVA AVW+A+ RP + GD+ A L RWSL+ S+ Sbjct 296 IVRAVACAVWDAQ---FDGRPFTVNGGDDHAWEGLHRWSLVHSE 336 >gi|254775531|ref|ZP_05217047.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium avium subsp. avium ATCC 25291] Length=345 Score = 468 bits (1203), Expect = 9e-130, Method: Compositional matrix adjust. Identities = 255/344 (75%), Positives = 289/344 (85%), Gaps = 7/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 +K++AQ+HDCLLIDLDGT F GR PT GAVQ+L+++ R LFVTNNASRSA EVAAHL E Sbjct 9 VKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGRALFVTNNASRSAGEVAAHLTE 68 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAAHLLAGQL GA VLIVGTEALA E+AAVGLRPVRR++D P A Sbjct 69 LGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGTEALAGEIAAVGLRPVRRYDDGPVA 128 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMT GW DLAEAALAIRAGA+WVAAN+D TLPTERGLLPGNGS+VAA+ ATG Sbjct 129 VVQGLSMTIGWPDLAEAALAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGAT 188 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPAL+ +A ARGDFRA LV+GDRLDTDIEGANAAGLPSL+VLTGVNSA DAVY Sbjct 189 PQVAGKPAPALLRDAAARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVY 248 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RRPTY+GHDLR+LHQD+ LAVAPQPGW+++VG A+TV +G DD DGLS Sbjct 249 AKPARRPTYVGHDLRALHQDAAALAVAPQPGWRVEVGDTAITVSGDGR-DDRS--GDGLS 305 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 +VRAVASAVW A L I AGD+RARAAL RWSL+R+D Sbjct 306 VVRAVASAVWGLPDAGT----LPIRAGDDRARAALARWSLVRTD 345 >gi|118617309|ref|YP_905641.1| phosphatase [Mycobacterium ulcerans Agy99] gi|118569419|gb|ABL04170.1| phosphatase [Mycobacterium ulcerans Agy99] Length=336 Score = 467 bits (1202), Expect = 1e-129, Method: Compositional matrix adjust. Identities = 254/344 (74%), Positives = 283/344 (83%), Gaps = 8/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MK+IAQE+DCLLIDLDGTVF G QPT GAV+SL +V +RKLFVTNNASRSA EVA HL E Sbjct 1 MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTARKLFVTNNASRSAGEVAVHLRE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT EDVVTSAQSAAHLLA L PG++VL+VGT+ALA+E++A GLRPVRRFED+PDA Sbjct 61 LGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGTDALADEISAAGLRPVRRFEDQPDA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLS+T GW +LAEAALAIRAGALWVAANVD TLPTERGLLPGNGS VAALRTATG Sbjct 121 VVQGLSLTIGWPELAEAALAIRAGALWVAANVDKTLPTERGLLPGNGSFVAALRTATGAQ 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKP P LM +AV RGDFRA LV+GDRLDTDIEGANAAGLPSLMVLTGV+SA DAV+ Sbjct 181 PQVAGKPGPQLMKDAVGRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVH 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+PV RPTYIGHDLRSL QD LAVAPQ GW++ V G AVTV ANG E D LS Sbjct 241 ADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVDGAAVTVSANG-----EQAGDDLS 295 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 IVRAVA AVW+A+ RP + GD+ A L RWSL+ S+ Sbjct 296 IVRAVACAVWDAQ---FDGRPFTVNGGDDHAWERLHRWSLVHSE 336 >gi|41407497|ref|NP_960333.1| hypothetical protein MAP1399 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395850|gb|AAS03716.1| hypothetical protein MAP_1399 [Mycobacterium avium subsp. paratuberculosis K-10] Length=337 Score = 462 bits (1190), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 255/344 (75%), Positives = 287/344 (84%), Gaps = 7/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MK++AQ+HDCLLIDLDGT F GR PT GAVQ+L+++ R LFVTNNASRSA EVAAHL E Sbjct 1 MKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGRALFVTNNASRSAAEVAAHLTE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAAHLLAGQL GA VLIVGTEALA E+AAVGLRPVRR++D P A Sbjct 61 LGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGTEALAGEIAAVGLRPVRRYDDGPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMT GW DLAEAALAIRAGA+WVAAN+D TLPTERGLLPGNGS+VAA+ ATG Sbjct 121 VVQGLSMTIGWPDLAEAALAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGAT 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPAL+ +A ARGDFRA LV+GDRLDTDIEGANAAGLPSL+VLTGVNSA DAVY Sbjct 181 PQVAGKPAPALLRDAAARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVY 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RRPTYIGHDLR+LHQD+ LAVAPQPGW++DVG A+TV +G D LS Sbjct 241 AKPARRPTYIGHDLRALHQDAAALAVAPQPGWRVDVGDTAITVSGDGRDDGSGDG---LS 297 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 +VRAVASAVW + A L I AGD+RARAAL RWSL+R+D Sbjct 298 VVRAVASAVWGSPDAGT----LPIRAGDDRARAALARWSLVRTD 337 >gi|296164592|ref|ZP_06847159.1| hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900011|gb|EFG79450.1| hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=333 Score = 462 bits (1189), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 250/340 (74%), Positives = 282/340 (83%), Gaps = 8/340 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M SIA ++DCLL+DLDGT+F GR+ T GAVQ+L++VRSR FVTNNASRSA EVAAHL E Sbjct 1 MTSIACQYDCLLLDLDGTLFRGRRATEGAVQALAEVRSRAFFVTNNASRSAAEVAAHLNE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAA LLA QL G+ VLIVGT+ALA EVAAVGLRPVRR++D P A Sbjct 61 LGFTATADDVATSAQSAARLLAAQLPAGSPVLIVGTDALAGEVAAVGLRPVRRYDDDPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLS T GW DLAEAALAIR+GALWVAANVDPTLPTERGLLPGNGSMVAALR ATG + Sbjct 121 VVQGLSTTIGWPDLAEAALAIRSGALWVAANVDPTLPTERGLLPGNGSMVAALRAATGAE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPAL+T+A ARGDFRA LVVGDRLDTDIEGANAA LPSLMVLTGV+SA DAVY Sbjct 181 PQVAGKPAPALLTDAAARGDFRAPLVVGDRLDTDIEGANAAKLPSLMVLTGVSSARDAVY 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RPTYIGHDLR+LH D++ LAV PQPGW+++VG AVTV + DGL+ Sbjct 241 ADPAHRPTYIGHDLRALHADAERLAVGPQPGWRVEVGERAVTVSGD-----GPDDGDGLA 295 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSL 340 IVRAVA AVW A + RP+ +EAGD RAR AL+RWSL Sbjct 296 IVRAVAGAVWSAGS---DGRPVGVEAGDARAREALRRWSL 332 >gi|118466906|ref|YP_882263.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium avium 104] gi|118168193|gb|ABK69090.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium avium 104] Length=340 Score = 462 bits (1188), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 254/344 (74%), Positives = 287/344 (84%), Gaps = 7/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 +K++AQ+HDCLLIDLDGT F GR PT GAVQ+L+++ R LFVTNNASRSA EVAAHL E Sbjct 4 VKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGRALFVTNNASRSAGEVAAHLTE 63 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAAHLLAGQL GA VLIVGTEALA E+AAVGLRPVRR++D P A Sbjct 64 LGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGTEALAGEIAAVGLRPVRRYDDGPVA 123 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMT GW DLAEAALAIRAGA+WVAAN+D TLPTERGLLPGNGS+VAA+ ATG Sbjct 124 VVQGLSMTIGWPDLAEAALAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGAT 183 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPAL+ +A ARGDFRA LV+GDRLDTDIEGANAAGLPSL+VLTGVNSA DAVY Sbjct 184 PQVAGKPAPALLRDAAARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVY 243 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RRPTYIGHDLR+LHQD+ LAVAPQPGW++DVG A+TV +G D LS Sbjct 244 AKPARRPTYIGHDLRALHQDAAALAVAPQPGWRVDVGDTAITVSGDGRDDGSGDG---LS 300 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 +VRAVASAVW + A L I AGD+RARAAL RWSL+R+D Sbjct 301 VVRAVASAVWGSPDAGT----LPIRAGDDRARAALARWSLVRTD 340 >gi|336457851|gb|EGO36845.1| putative sugar phosphatase of HAD superfamily [Mycobacterium avium subsp. paratuberculosis S397] Length=340 Score = 461 bits (1186), Expect = 8e-128, Method: Compositional matrix adjust. Identities = 254/344 (74%), Positives = 287/344 (84%), Gaps = 7/344 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 +K++AQ+HDCLLIDLDGT F GR PT GAVQ+L+++ R LFVTNNASRSA EVAAHL E Sbjct 4 VKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGRALFVTNNASRSAAEVAAHLTE 63 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAAHLLAGQL GA VLIVGTEALA E+AAVGLRPVRR++D P A Sbjct 64 LGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGTEALAGEIAAVGLRPVRRYDDGPVA 123 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQGLSMT GW DLAEAALAIRAGA+WVAAN+D TLPTERGLLPGNGS+VAA+ ATG Sbjct 124 VVQGLSMTIGWPDLAEAALAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGAT 183 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPAL+ +A ARGDFRA LV+GDRLDTDIEGANAAGLPSL+VLTGVNSA DAVY Sbjct 184 PQVAGKPAPALLRDAAARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVY 243 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RRPTYIGHDLR+LHQD+ LAVAPQPGW++DVG A+TV +G D LS Sbjct 244 AKPARRPTYIGHDLRALHQDAAALAVAPQPGWRVDVGDTAITVSGDGRDDGSGDG---LS 300 Query 301 IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 +VRAVASAVW + A L I AGD+RARAAL RWSL+R+D Sbjct 301 VVRAVASAVWGSPDAGT----LPIRAGDDRARAALARWSLVRTD 340 >gi|342860730|ref|ZP_08717380.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium colombiense CECT 3035] gi|342131754|gb|EGT85011.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium colombiense CECT 3035] Length=341 Score = 437 bits (1125), Expect = 9e-121, Method: Compositional matrix adjust. Identities = 248/343 (73%), Positives = 281/343 (82%), Gaps = 9/343 (2%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCEL 61 K++AQ+HDCLLIDLDGT+F GR+PT GAV++L++VRSR FVTNNASRSADEVAAHL EL Sbjct 8 KTLAQQHDCLLIDLDGTMFRGRRPTEGAVRALAEVRSRAYFVTNNASRSADEVAAHLTEL 67 Query 62 GFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAV 121 GFTA +DV TSAQSAA LLA QLAPG+ VLIVGTEALA+E+ AVGLR VR ++D P AV Sbjct 68 GFTAVADDVATSAQSAARLLADQLAPGSPVLIVGTEALADEITAVGLRAVRSYDDEPAAV 127 Query 122 VQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDP 181 VQGLS T GW +LAEAALAIRAGALWVA+NVD TLPTERGLLPGNGS VAALR ATG DP Sbjct 128 VQGLSQTIGWPELAEAALAIRAGALWVASNVDLTLPTERGLLPGNGSFVAALRAATGGDP 187 Query 182 RVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYA 241 +VAGKPAP L+ +A ARGDFRA LVVGDRLDTDIEGANAA LPSLMVLTGVNSA DAVYA Sbjct 188 QVAGKPAPGLLRDAAARGDFRAPLVVGDRLDTDIEGANAAELPSLMVLTGVNSARDAVYA 247 Query 242 EPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSI 301 P +RPTYIGHDLRSLH D++ LAV PQPGW+++V +TV A+G D DGL++ Sbjct 248 NPGQRPTYIGHDLRSLHADAESLAVGPQPGWRVEVADATITVSADGAGD-----GDGLAV 302 Query 302 VRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 344 VRAVA AV +RIEA D+RARAALQRWSL+ SD Sbjct 303 VRAVAGAV----YGAAGSGEVRIEAADDRARAALQRWSLVHSD 341 >gi|333990488|ref|YP_004523102.1| phosphatase [Mycobacterium sp. JDM601] gi|333486456|gb|AEF35848.1| phosphatase [Mycobacterium sp. JDM601] Length=542 Score = 402 bits (1034), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 224/340 (66%), Positives = 261/340 (77%), Gaps = 8/340 (2%) Query 3 SIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELG 62 ++A E+DCLL+DLDGTVF G +PT GAV++L+++ SR LF+TNN+SR ADEVAAHL LG Sbjct 206 ALADEYDCLLLDLDGTVFRGGEPTVGAVETLAELPSRALFITNNSSRGADEVAAHLNRLG 265 Query 63 FTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVV 122 FTA EDV TSAQ AAHLLA QL G+RVL+VGTE+LA E+AA GL PVR D P AVV Sbjct 266 FTAAAEDVATSAQIAAHLLAEQLPAGSRVLVVGTESLAAEIAAAGLEPVRLASDEPAAVV 325 Query 123 QGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPR 182 QGLS TGW+ LAEAALAIRAGA+W+ NVD TLP+ERGLLPGNGSMVAALR AT +P+ Sbjct 326 QGLSTETGWAQLAEAALAIRAGAMWMTTNVDKTLPSERGLLPGNGSMVAALRAATDAEPQ 385 Query 183 VAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAE 242 VAGKP PAL+TEA+ RG+F A LVVGDRLDTDI ANAA LPSLMVLTGVNSA DAV A Sbjct 386 VAGKPGPALLTEALTRGEFYAPLVVGDRLDTDIAAANAAALPSLMVLTGVNSARDAVGAV 445 Query 243 PVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVC-ANGDVDDLEFIDDGLSI 301 +RPTYIGHDLR+L D+ LA+ PQP WQI V G +TV A + DD DGLSI Sbjct 446 AEQRPTYIGHDLRALLLDADGLAIGPQPQWQISVDGTTLTVAGAQPEEDD----SDGLSI 501 Query 302 VRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLM 341 VRA+A AV E A+L RP +E+ D+ A ALQ WSL+ Sbjct 502 VRALAGAVAE---AELAGRPFTVESADDTAAQALQHWSLL 538 >gi|120404267|ref|YP_954096.1| HAD family hydrolase [Mycobacterium vanbaalenii PYR-1] gi|119957085|gb|ABM14090.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium vanbaalenii PYR-1] Length=337 Score = 402 bits (1033), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 220/342 (65%), Positives = 266/342 (78%), Gaps = 11/342 (3%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M ++AQ+HDCLL+DLDGTVF G +PT GAV +L+ V SR LFVTNNASR A++VA HL E Sbjct 1 MTTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLASVDSRILFVTNNASRDAEQVAEHLRE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF A +DVVTSAQSAA LLAGQ+ PG RVL+VGT+ALA+E++ VGL PVRR+ DRP A Sbjct 61 LGFAAAADDVVTSAQSAARLLAGQVPPGGRVLVVGTDALADEISGVGLEPVRRWSDRPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S TGW LAEAALAIR+GALWVAANVD TLP+E GLLPGNGSMVAALRTAT D Sbjct 121 VVQGHSPDTGWQHLAEAALAIRSGALWVAANVDKTLPSEHGLLPGNGSMVAALRTATDAD 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPALM +A+ARG+F LVVGDRLDTDI GANAA LPSLMVL GVNSA DA++ Sbjct 181 PQVAGKPAPALMQDALARGEFDRPLVVGDRLDTDIAGANAARLPSLMVLCGVNSAEDAIW 240 Query 241 AEPVRRPTYIGHDLRSLH-QDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGL 299 A +RPT++ DLR+L D++ L +AP PGW+++V AVT+ A G D L Sbjct 241 AVREQRPTFLAADLRALTADDTEALRIAPHPGWRVEVDNVAVTLTATG-----SDPGDSL 295 Query 300 SIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLM 341 + VRA+A+AVW A+ + +RP+R D+ AR A+QRWSL+ Sbjct 296 APVRAIAAAVW---ASGIARRPIR--GHDDTARQAVQRWSLV 332 >gi|118469538|ref|YP_888050.1| hydrolase [Mycobacterium smegmatis str. MC2 155] gi|118170825|gb|ABK71721.1| hydrolase [Mycobacterium smegmatis str. MC2 155] Length=342 Score = 387 bits (993), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 213/342 (63%), Positives = 257/342 (76%), Gaps = 6/342 (1%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M ++A++HDCLL+DLDGTVF G + T GAV+SL+ + +R L+VTNNASR+ +VA HL E Sbjct 1 MTTLARQHDCLLLDLDGTVFRGHEATPGAVESLAGLDARLLYVTNNASRAPQQVAEHLRE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF+ +DVVTSAQSAA +LA QL ARVL+VGTEALA+EV VGLRPVR+F + P A Sbjct 61 LGFSGDADDVVTSAQSAARVLAAQLPADARVLVVGTEALADEVRNVGLRPVRQFAEDPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG + TGW+DLAEAALAIRAGALWVAANVD TLP+ERGLLPGNGSMVAALR ATG D Sbjct 121 VVQGHNPQTGWADLAEAALAIRAGALWVAANVDLTLPSERGLLPGNGSMVAALRVATGHD 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKP P LM +A++RG F A LVVGDRLDTDI A +AGLPSLMVL+GV++A DAV+ Sbjct 181 PQVAGKPQPTLMRDALSRGSFEAPLVVGDRLDTDIACAVSAGLPSLMVLSGVSTATDAVF 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A RP YI DLRSLH ++ L V PQP W+++V V V + G V DD LS Sbjct 241 AAEHERPDYIAADLRSLHVAAETLRVGPQPEWRVEVDSDRVEVYSTGKV-----TDDPLS 295 Query 301 IVRAVASAVWEARAADLHQRP-LRIEAGDERARAALQRWSLM 341 +VRAVA AVW ++ + AGD+ ARAALQR SL+ Sbjct 296 VVRAVAHAVWTDSDDHVYDNDGYTLVAGDDTARAALQRASLL 337 >gi|145224095|ref|YP_001134773.1| HAD family hydrolase [Mycobacterium gilvum PYR-GCK] gi|315444432|ref|YP_004077311.1| sugar phosphatase of HAD superfamily [Mycobacterium sp. Spyr1] gi|145216581|gb|ABP45985.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium gilvum PYR-GCK] gi|315262735|gb|ADT99476.1| predicted sugar phosphatase of HAD superfamily [Mycobacterium sp. Spyr1] Length=337 Score = 380 bits (977), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 209/341 (62%), Positives = 258/341 (76%), Gaps = 11/341 (3%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M ++AQ+HDCLL+DLDGTVF G +PT GAV +L+ V +R LFVTNNASRSA +V+ HLCE Sbjct 1 MSTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLAGVDTRILFVTNNASRSAGQVSDHLCE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF+A DVVTSAQSAA LLA QL GA+VL+VGT++LA+EV+ VGL PVR + + P A Sbjct 61 LGFSAAPPDVVTSAQSAARLLAEQLPSGAKVLVVGTDSLADEVSNVGLAPVREYSEGPAA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG + T W LAEAALAIR+GALWVAANVD TLP+ERGLLPGNGSMVAALR AT + Sbjct 121 VVQGHNPETAWQILAEAALAIRSGALWVAANVDRTLPSERGLLPGNGSMVAALRAATDSE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P+VAGKPAPALM +A++RGDF+ LVVGDRLDTDI GANAA LPSLMVL GVN+A DA++ Sbjct 181 PQVAGKPAPALMADALSRGDFQTPLVVGDRLDTDIAGANAARLPSLMVLCGVNNAADAIW 240 Query 241 AEPVRRPTYIGHDLRSLH-QDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGL 299 A RP ++ DLR+L + +L +AP P W++DV AVTV + G D L Sbjct 241 AVEDERPGFLAEDLRALTAHAADVLRIAPDPAWRVDVTEKAVTVSSTGTT-----ASDPL 295 Query 300 SIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSL 340 + VRA+A+AVWE + + +RP I D+ AR A++RWSL Sbjct 296 APVRAIAAAVWE---SGIGRRP--IVGADDAARQAVERWSL 331 >gi|289569740|ref|ZP_06449967.1| predicted protein [Mycobacterium tuberculosis T17] gi|289543494|gb|EFD47142.1| predicted protein [Mycobacterium tuberculosis T17] Length=185 Score = 370 bits (950), Expect = 2e-100, Method: Compositional matrix adjust. Identities = 185/185 (100%), Positives = 185/185 (100%), Gaps = 0/185 (0%) Query 169 MVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMV 228 MVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMV Sbjct 1 MVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMV 60 Query 229 LTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGD 288 LTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGD Sbjct 61 LTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGD 120 Query 289 VDDLEFIDDGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVT 348 VDDLEFIDDGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVT Sbjct 121 VDDLEFIDDGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVT 180 Query 349 SVGTQ 353 SVGTQ Sbjct 181 SVGTQ 185 >gi|108799919|ref|YP_640116.1| HAD family hydrolase [Mycobacterium sp. MCS] gi|119869029|ref|YP_938981.1| HAD family hydrolase [Mycobacterium sp. KMS] gi|108770338|gb|ABG09060.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. MCS] gi|119695118|gb|ABL92191.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. KMS] Length=334 Score = 360 bits (925), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 215/338 (64%), Positives = 254/338 (76%), Gaps = 12/338 (3%) Query 6 QEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTA 65 Q+HDCLL+DLDGTVF G +PT GAV+SL+ + +R L+VTNNASRS +VA HL ELGF A Sbjct 2 QQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFHA 61 Query 66 TGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGL 125 DVVTSAQSAAHLLA QL GARVL+VGTEALA EV VGL+PVR+F D P AVVQG Sbjct 62 DAADVVTSAQSAAHLLAAQLPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQGH 121 Query 126 SMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAG 185 + T W+DLAEAALA+RAGALWVAANVD TLP+ERGLLPGNGSMVAAL+ AT +P+VAG Sbjct 122 NPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLPGNGSMVAALQAATAREPQVAG 181 Query 186 KPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVR 245 KP P LM +A++RGDF LVVGDRLDTDI GANAA LPSLMVL+GV++A + + A P Sbjct 182 KPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQE 241 Query 246 RPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFID--DGLSIVR 303 RP YI DLRSL + L V P PGW+I+V G VTV A+G +D D LS++R Sbjct 242 RPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADG-------VDRGDDLSVLR 294 Query 304 AVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLM 341 A A VW+ +DL P + AGD+ A AALQRWSL+ Sbjct 295 ATAHVVWQ---SDLAGTPFAVRAGDDTAAAALQRWSLL 329 >gi|126435547|ref|YP_001071238.1| HAD family hydrolase [Mycobacterium sp. JLS] gi|126235347|gb|ABN98747.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. JLS] Length=334 Score = 356 bits (914), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 213/336 (64%), Positives = 251/336 (75%), Gaps = 8/336 (2%) Query 6 QEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTA 65 Q+HDCLL+DLDGTVF G +PT GAV+SL+ + +R L+VTNNASRS +VA HL ELGF A Sbjct 2 QQHDCLLLDLDGTVFRGHEPTTGAVESLAALSARVLYVTNNASRSPGDVAGHLVELGFDA 61 Query 66 TGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGL 125 DVVTSAQSAAHLLA QL GARVL+VGTEALA EV VGL+PVR+F D P AVVQG Sbjct 62 DAADVVTSAQSAAHLLAAQLPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQGH 121 Query 126 SMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAG 185 + T W+DLAEAALA+RAGALWVAANVD TLP+ERGLLPGNGSMVAAL+ AT +P+VAG Sbjct 122 NPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLPGNGSMVAALQAATAREPQVAG 181 Query 186 KPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVR 245 KP P LM +A++RGDF LVVGDRLDTDI GANAA LPSLMVL+GV++A + + A P Sbjct 182 KPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQE 241 Query 246 RPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSIVRAV 305 RP YI DLRSL + L V P PGW+I+V VTV A+G D LS++RA Sbjct 242 RPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDDTDVTVHADG-----ADRGDDLSVLRAT 296 Query 306 ASAVWEARAADLHQRPLRIEAGDERARAALQRWSLM 341 A VW+ ADL P + AGD+ A AAL+RWSL+ Sbjct 297 AHVVWQ---ADLAGTPFAVRAGDDTAAAALRRWSLL 329 >gi|169629443|ref|YP_001703092.1| HAD-superfamily hydrolase [Mycobacterium abscessus ATCC 19977] gi|169241410|emb|CAM62438.1| HAD-superfamily hydrolase [Mycobacterium abscessus] Length=334 Score = 326 bits (835), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 184/272 (68%), Positives = 212/272 (78%), Gaps = 1/272 (0%) Query 3 SIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNNASRSADEVAAHLCEL 61 ++A +DCLL+DLDGTVF G +PT A++SL+ +R+L+VTNNASRSA EVA HL L Sbjct 4 TLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHLAAL 63 Query 62 GFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAV 121 GFTA DVVTSAQSAA LLA +L G VL+VGTEALA EVAAVGL PVR F++ P AV Sbjct 64 GFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAPRAV 123 Query 122 VQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDP 181 VQG S TGW+ LAEAALAIRAGA WVAANVD TLPTERGLLPGNGSMVAALRTAT DP Sbjct 124 VQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPTERGLLPGNGSMVAALRTATDADP 183 Query 182 RVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYA 241 VAGKP AL+ +A+ARG F LVVGDRLDTDI GAN AGLPSLMVLTGVNSA DA++A Sbjct 184 VVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDAIWA 243 Query 242 EPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQ 273 + RPT++G DL +LH + + P+P WQ Sbjct 244 DIAHRPTFLGADLSALHLPQADVRIEPKPSWQ 275 >gi|262202729|ref|YP_003273937.1| HAD-superfamily hydrolase [Gordonia bronchialis DSM 43247] gi|262086076|gb|ACY22044.1| HAD-superfamily hydrolase, subfamily IIA [Gordonia bronchialis DSM 43247] Length=675 Score = 312 bits (800), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 175/328 (54%), Positives = 221/328 (68%), Gaps = 8/328 (2%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCEL 61 +++A +D LL+DLDGTVF G + AV SL++ + + FVTNNASR EVAAHL +L Sbjct 341 RTLADSYDALLLDLDGTVFAGHRALPHAVDSLARTSTARFFVTNNASRRPAEVAAHLTDL 400 Query 62 GFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAV 121 GF AT + VVTSAQSAA LL+ L PG+R L++GT+ LA EV G+ R +DRP AV Sbjct 401 GFDATPDLVVTSAQSAARLLSEHLEPGSRALVIGTDGLAQEVREAGIGVTRSADDRPAAV 460 Query 122 VQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDP 181 +QG S TGW+ L+EAALAIRAGALW+A NVD TLP+ERGLL GNGSMVAA+R ATG +P Sbjct 461 IQGHSPETGWAQLSEAALAIRAGALWIATNVDATLPSERGLLVGNGSMVAAVRNATGAEP 520 Query 182 RVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYA 241 VAGKPA LM +A+AR R LVVGDRLDTDIEGA+A G+ S +VLTGV++ D + A Sbjct 521 IVAGKPAAPLMADAIARSRARTPLVVGDRLDTDIEGAHAVGIDSALVLTGVSTVPDLLIA 580 Query 242 EPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSI 301 P +RPTY+ DL L D + + V PQPGW ++V V V + D +S+ Sbjct 581 PPEQRPTYVIDDLAGLFDDPESVRVGPQPGWNVEVFDSRVVVTPDDDA-------AAVSM 633 Query 302 VRAVASAVWEA-RAADLHQRPLRIEAGD 328 V AV A+W A D+ L + AGD Sbjct 634 VPAVVHAIWAAIDGTDVDVDTLSVAAGD 661 >gi|333919191|ref|YP_004492772.1| phosphatase [Amycolicicoccus subflavus DQS3-9A1] gi|333481412|gb|AEF39972.1| Phosphatase [Amycolicicoccus subflavus DQS3-9A1] Length=358 Score = 303 bits (776), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 187/343 (55%), Positives = 234/343 (69%), Gaps = 8/343 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRS-RKLFVTNNASRSADEVAAHLC 59 M + +E D LL+DLDGT++ G Q AV L V S R L+VTNNASRSA +VA HL Sbjct 1 MARLFEEFDSLLLDLDGTLYRGPQVVPHAVDVLHHVGSTRLLYVTNNASRSASDVATHLA 60 Query 60 ELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPD 119 ELGF AT EDVVTSAQ+AA L++ ++PG++VL+VGT+A A+E+ L PV RF++ PD Sbjct 61 ELGFAATSEDVVTSAQAAARLVSSLVSPGSKVLVVGTDAFADEIRKANLVPVTRFDEGPD 120 Query 120 AVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGM 179 AVVQG S TGW+ LAEAALAIR+GA+WVAAN+D TLPTERGLLPGNGSMVAA+RTAT + Sbjct 121 AVVQGHSPDTGWALLAEAALAIRSGAVWVAANLDATLPTERGLLPGNGSMVAAVRTATDV 180 Query 180 DPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAV 239 +P VAGKP + +A+ R + LVVGDRLDTDI GA AAGLPSL V+TGV+ D + Sbjct 181 EPYVAGKPGSQIFKDAIERASLSSPLVVGDRLDTDIAGARAAGLPSLYVMTGVSQPLDVL 240 Query 240 YAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCA--NGDVDDLEFIDD 297 A P RP YI DLRSL + ++ L APQ GW + G V + A N DVD+ + D Sbjct 241 RAGPDMRPDYIAADLRSLGELAERLRPAPQRGWDVFWDGPNVVITATDNADVDNADT--D 298 Query 298 GLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSL 340 G + +RA AS +W A A + RI RA L+ WS+ Sbjct 299 GAAALRAAASTLWSAAAP---ETVTRIVVRGARAAQLLRAWSV 338 >gi|343928396|ref|ZP_08767844.1| hypothetical protein GOALK_117_00020 [Gordonia alkanivorans NBRC 16433] gi|343761581|dbj|GAA14770.1| hypothetical protein GOALK_117_00020 [Gordonia alkanivorans NBRC 16433] Length=611 Score = 298 bits (763), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 165/288 (58%), Positives = 203/288 (71%), Gaps = 0/288 (0%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCEL 61 +++ +D LL+DLDGTVF G Q AV +L ++ + FVTNNASR EVAAHL EL Sbjct 278 QALVDRYDALLLDLDGTVFAGHQALPNAVDTLDRLDIPRFFVTNNASRRPAEVAAHLREL 337 Query 62 GFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAV 121 GF AT + VVTSAQS A LL+ L PG+R L++GT+ LA EV VG+ R +DRP AV Sbjct 338 GFDATDDLVVTSAQSGARLLSEHLPPGSRALVIGTDGLAQEVREVGIGVTRSADDRPAAV 397 Query 122 VQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDP 181 +QG S TGW+ L+EAALAIRAGALWVA NVD TLP+ERGLL GNGSMVAALR ATG +P Sbjct 398 IQGHSTDTGWAQLSEAALAIRAGALWVATNVDATLPSERGLLVGNGSMVAALRNATGKEP 457 Query 182 RVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYA 241 VAGKPA LM +A+AR + LVVGDRLDTDIEGA+A G+ S +VLTGV++ D + A Sbjct 458 LVAGKPAAPLMADAIARAAANSPLVVGDRLDTDIEGAHAVGIESALVLTGVSTVTDLLAA 517 Query 242 EPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDV 289 P +RPTY+ DL + + + VA QPGW + V VTV +GDV Sbjct 518 PPEQRPTYVIEDLAGVFDEIDAVRVADQPGWTVSVEASTVTVSGSGDV 565 >gi|325674264|ref|ZP_08153953.1| hydrolase [Rhodococcus equi ATCC 33707] gi|325554944|gb|EGD24617.1| hydrolase [Rhodococcus equi ATCC 33707] Length=344 Score = 297 bits (760), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 168/281 (60%), Positives = 200/281 (72%), Gaps = 0/281 (0%) Query 3 SIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELG 62 S+ HD LL+DLDGTV+ GR+ GA ++L R+L+VTNNASRS EVA HL ELG Sbjct 12 SLRAGHDVLLLDLDGTVYQGREVIPGAREALEAGNERQLYVTNNASRSPAEVAEHLRELG 71 Query 63 FTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVV 122 F A +DVVTS+QSAA LLA L G+ VL+VGTEAL +EV VGLR VRRF D P AVV Sbjct 72 FDAADDDVVTSSQSAARLLAEHLDTGSTVLVVGTEALCDEVEKVGLRAVRRFVDAPVAVV 131 Query 123 QGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPR 182 QG S T W+ LAEA LAIRAGALW+AANVD TLPTERGL+ GNGSMVAALRTATG +P Sbjct 132 QGHSPATDWAILAEATLAIRAGALWIAANVDSTLPTERGLVLGNGSMVAALRTATGREPI 191 Query 183 VAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAE 242 VAGKPA LM +A+ R LVVGDRLDTDI GANA + SL+VLTGV++ D + A+ Sbjct 192 VAGKPAAPLMHDALDRARASRPLVVGDRLDTDIAGANAVDVESLLVLTGVSTTADLLRAD 251 Query 243 PVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTV 283 RPTY+ L +L++ ++ AV PGWQ + G V V Sbjct 252 VEHRPTYVAASLDALNRPAEESAVTAHPGWQANFEAGDVVV 292 >gi|312139858|ref|YP_004007194.1| haloacid dehalogenase-like hydrolase [Rhodococcus equi 103S] gi|311889197|emb|CBH48511.1| putative haloacid dehalogenase-like hydrolase [Rhodococcus equi 103S] Length=344 Score = 296 bits (758), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 167/281 (60%), Positives = 199/281 (71%), Gaps = 0/281 (0%) Query 3 SIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELG 62 S+ HD LL+DLDGTV+ GR+ GA ++L R+L+VTNNASRS EVA HL ELG Sbjct 12 SLRAGHDVLLLDLDGTVYQGREVIPGAREALEAGNERQLYVTNNASRSPAEVAEHLRELG 71 Query 63 FTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVV 122 F A +DVVTS+QSAA LLA L G+ VL+VGTEAL +EV VGLR VRRF D P AV Sbjct 72 FDAADDDVVTSSQSAARLLAEHLDTGSAVLVVGTEALCDEVEKVGLRAVRRFVDAPVAVA 131 Query 123 QGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPR 182 QG S T W+ LAEA LAIRAGALW+AANVD TLPTERGL+ GNGSMVAALRTATG +P Sbjct 132 QGHSPATDWAILAEATLAIRAGALWIAANVDSTLPTERGLVLGNGSMVAALRTATGREPI 191 Query 183 VAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAE 242 VAGKPA LM +A+ R LVVGDRLDTDI GANA + SL+VLTGV++ D + A+ Sbjct 192 VAGKPAAPLMHDALDRARASRPLVVGDRLDTDIAGANAVDVESLLVLTGVSTTADLLRAD 251 Query 243 PVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTV 283 RPTY+ L +L++ ++ AV PGWQ + G V V Sbjct 252 VEHRPTYVAASLEALNRPAEESAVTAHPGWQANFEAGDVVV 292 >gi|226360085|ref|YP_002777863.1| hydrolase [Rhodococcus opacus B4] gi|226238570|dbj|BAH48918.1| putative hydrolase [Rhodococcus opacus B4] Length=331 Score = 293 bits (750), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 167/311 (54%), Positives = 213/311 (69%), Gaps = 3/311 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M ++ + +D LL+DLDGT++ G Q GA ++L+ +VTNNASRS +VA HL + Sbjct 1 MTALRENYDALLLDLDGTLYQGPQEIPGAREALAAGMQSCYYVTNNASRSPGDVAEHLTD 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF A VVTS+QSAA LLA +APG+ VL+VGTEALA+EV VGLRPVR FED P A Sbjct 61 LGFEAGESTVVTSSQSAARLLAENVAPGSPVLVVGTEALADEVRNVGLRPVRSFEDAPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S TT W+ LAEA L+IRAGA+WVAAN+D TLPTERGL+ GNGSMVAALRTAT + Sbjct 121 VVQGHSPTTDWAILAEATLSIRAGAVWVAANLDSTLPTERGLVLGNGSMVAALRTATSRE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKPA LM +A+ R LVVGDRLDTDIEGAN GL SL+VLTGV++A D + Sbjct 181 PLVAGKPAAPLMEDAMRRSGCVRPLVVGDRLDTDIEGANNVGLDSLLVLTGVSTAIDVLR 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A P +RPTY+ +L +L++ + V W ++ G + + D + D + Sbjct 241 AAPEQRPTYVASELDALNRPADESLVGEDSRWSVEFDGTDLVIEPTADSAEPM---DSAA 297 Query 301 IVRAVASAVWE 311 ++RAVA W+ Sbjct 298 LLRAVAVGAWK 308 >gi|226306755|ref|YP_002766715.1| hypothetical protein RER_32680 [Rhodococcus erythropolis PR4] gi|226185872|dbj|BAH33976.1| conserved hypothetical protein [Rhodococcus erythropolis PR4] Length=327 Score = 286 bits (733), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 166/310 (54%), Positives = 204/310 (66%), Gaps = 7/310 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M + ++D LL+DLDGT++ G G +L Q +VTNNASRS V+AHL E Sbjct 1 MTVLRTQYDVLLLDLDGTLYAGAHAIPGTQAALGQGTQALYYVTNNASRSPSAVSAHLTE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF + + VVTS+Q+A LLA +L PGA VL+VGT+ALA+EV VGL PVR F D P A Sbjct 61 LGFDSEDDRVVTSSQTAVRLLAERLEPGAAVLVVGTDALADEVTRVGLLPVREFADSPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S T WS LAEA LAIRAGALWVAAN+D TLP+ERGL+ GNGSMVAALR AT + Sbjct 121 VVQGHSTETNWSILAEACLAIRAGALWVAANLDTTLPSERGLVLGNGSMVAALRAATRQE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKPA LM +A+AR LVVGDRLDTDIEGA+A + SL+VLTGV++ D + Sbjct 181 PLVAGKPAAPLMEDALARSGCSRPLVVGDRLDTDIEGAHAVSIDSLLVLTGVSTPGDVLR 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A +RPTYI L SL+Q + V W + V G A+ V D + D +S Sbjct 241 APIEQRPTYIAATLDSLNQPAVESLVGADSKWSVSVNGSALVV-------DGPVVGDEMS 293 Query 301 IVRAVASAVW 310 ++RAVA W Sbjct 294 LLRAVAPVAW 303 >gi|229494827|ref|ZP_04388581.1| HAD-superfamily hydrolase, subfamily IIA [Rhodococcus erythropolis SK121] gi|229318265|gb|EEN84132.1| HAD-superfamily hydrolase, subfamily IIA [Rhodococcus erythropolis SK121] Length=327 Score = 286 bits (731), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 165/310 (54%), Positives = 203/310 (66%), Gaps = 7/310 (2%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M + ++D LL+DLDGT++ G G +L Q +VTNNASRS V+AHL E Sbjct 1 MTVLRTQYDVLLLDLDGTLYAGAHAIPGTQAALGQGTQALYYVTNNASRSPSAVSAHLTE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF + + VVTS+Q+A LL+ +L PGA VL+VGT+ALA+EV VGL PVR F D P A Sbjct 61 LGFDSEDDRVVTSSQTAVRLLSERLEPGAAVLVVGTDALADEVTRVGLLPVREFADSPVA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S T WS LAEA LAIRAGALWVAAN+D TLP+ERGL+ GNGSMVAALR AT + Sbjct 121 VVQGHSTETNWSILAEACLAIRAGALWVAANLDTTLPSERGLVLGNGSMVAALRAATKQE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKPA LM +A+AR LVVGDRLDTDIEGA A + SL+VLTGV++ D + Sbjct 181 PLVAGKPAAPLMEDALARSGCSRPLVVGDRLDTDIEGAQAVSIDSLLVLTGVSTPGDVLR 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A +RPTYI L SL+Q + V W + V G A+ V D + D +S Sbjct 241 APVEQRPTYIAATLDSLNQPAVESLVGADSKWSVSVNGSALVV-------DGPVVGDEMS 293 Query 301 IVRAVASAVW 310 ++RAVA W Sbjct 294 LLRAVAPLAW 303 >gi|111017954|ref|YP_700926.1| phosphatase [Rhodococcus jostii RHA1] gi|110817484|gb|ABG92768.1| possible phosphatase [Rhodococcus jostii RHA1] Length=331 Score = 284 bits (727), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 160/278 (58%), Positives = 195/278 (71%), Gaps = 0/278 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M + +D LL+DLDGT++ G Q GA ++L+ +VTNNASRS EVA HL E Sbjct 1 MTVLRDGYDALLLDLDGTLYQGPQEIPGAREALAAGEQSCYYVTNNASRSPGEVAEHLTE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF A VVTS+QSAA LLA +AP + VLIVGTEALA EV VGLRPVR FED P A Sbjct 61 LGFDADESTVVTSSQSAARLLAENVAPDSPVLIVGTEALAGEVRNVGLRPVRSFEDAPAA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S TT W+ LAEA LAIRA A+WVAAN+D TLPTERGL+ GNGSMVAALRTA+ + Sbjct 121 VVQGHSPTTDWAILAEATLAIRADAVWVAANLDSTLPTERGLVLGNGSMVAALRTASSRE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKPA LM +A+ R LVVGDRLDTDIEGAN GL SL+VLTGV++A D + Sbjct 181 PLVAGKPAAPLMEDAMRRSGCARPLVVGDRLDTDIEGANNVGLDSLLVLTGVSTAVDVLR 240 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGG 278 A P +RPTY+ +L +L++ ++ + W ++ G Sbjct 241 AAPEQRPTYLASELDALNRPAEESLIGEDSRWSVEFDG 278 >gi|326384770|ref|ZP_08206447.1| HAD-superfamily hydrolase [Gordonia neofelifaecis NRRL B-59395] gi|326196578|gb|EGD53775.1| HAD-superfamily hydrolase [Gordonia neofelifaecis NRRL B-59395] Length=562 Score = 270 bits (689), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 148/281 (53%), Positives = 190/281 (68%), Gaps = 0/281 (0%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATG 67 +D LL+DLDGT++ G + GAV++++ LFVTNNASRS DEV HL +GF A Sbjct 236 YDVLLLDLDGTLYTGAEVLPGAVEAVAATDGTALFVTNNASRSPDEVRDHLVSMGFAAEA 295 Query 68 EDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSM 127 + VVTSAQ+ A LLAG + PGA VL+VG++AL EV A GL V ++ P AV+QG S Sbjct 296 DQVVTSAQAGAELLAGIVEPGAAVLVVGSDALRAEVRARGLGVVASADEAPAAVIQGHSP 355 Query 128 TTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKP 187 TGW+ L+EAALAIR+GA+WVA NVD TLPTERGL+ GNGSMVAA+ +AT P VAGKP Sbjct 356 DTGWAQLSEAALAIRSGAVWVATNVDSTLPTERGLMVGNGSMVAAVASATQRSPIVAGKP 415 Query 188 APALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRP 247 A +M A+AR + R L+VGDRLDTDIEGAN G+ SL+VL GV S + + AEP RP Sbjct 416 AAPIMRGALARAEARRPLMVGDRLDTDIEGANEVGIDSLLVLGGVTSGPELLAAEPALRP 475 Query 248 TYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGD 288 TY+ L +L P+P W ++V V+V + + Sbjct 476 TYVADGLNALTSPRSASTFGPRPEWSVEVNAQHVSVASRAE 516 >gi|302528027|ref|ZP_07280369.1| HAD-superfamily hydrolase [Streptomyces sp. AA4] gi|302436922|gb|EFL08738.1| HAD-superfamily hydrolase [Streptomyces sp. AA4] Length=325 Score = 268 bits (685), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 156/306 (51%), Positives = 196/306 (65%), Gaps = 13/306 (4%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAHLCELGFT 64 +D LL DLDGTV+ G Q GA ++++ VR + FVTNNAS++ VA HL +LG + Sbjct 6 YDALLFDLDGTVYHGPQVIEGAAETVTAVREQGTAVRFVTNNASKAPSAVAEHLRDLGIS 65 Query 65 ATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQG 124 A E+V TSAQ+AA LL +L GA+VLIVGT +L ++V+A GL PVR D AVVQG Sbjct 66 ADTEEVHTSAQAAAALLKDRLPVGAKVLIVGTASLGDQVSAAGLEPVRTAGDDVSAVVQG 125 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVA 184 S TGW+DLAEA++ IRAG LWVA N D TLPTERGL+PGNGSMV AL+ ATG +P VA Sbjct 126 HSPETGWADLAEASIVIRAGGLWVATNTDSTLPTERGLMPGNGSMVGALKIATGAEPVVA 185 Query 185 GKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPV 244 GKP P L A + LVVGDRLDTDI GA AAGL SL VLTG+ + + A P Sbjct 186 GKPQPLLFETAARSAKAKRPLVVGDRLDTDIAGAVAAGLDSLCVLTGIATPATLLTAIPA 245 Query 245 RRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSIVRA 304 RPT++GHDL +L Q L V + GW+I + DV + D L ++RA Sbjct 246 ERPTHLGHDLTALAQPVDELRVGKKSGWEI----------SESDVLTVRGEGDKLDLLRA 295 Query 305 VASAVW 310 + + W Sbjct 296 LCDSAW 301 >gi|257056538|ref|YP_003134370.1| putative sugar phosphatase of HAD superfamily [Saccharomonospora viridis DSM 43017] gi|256586410|gb|ACU97543.1| predicted sugar phosphatase of HAD superfamily [Saccharomonospora viridis DSM 43017] Length=336 Score = 263 bits (672), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 163/345 (48%), Positives = 207/345 (60%), Gaps = 16/345 (4%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAHL 58 +++ HD +L DLDGT++ G +P A ++++QVR R FVTNNAS+S D VA HL Sbjct 3 ETLLDRHDAVLFDLDGTIYHGTRPIPNAAEAVAQVRDRGRPVRFVTNNASKSPDAVAKHL 62 Query 59 CELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRP 118 +G A+ +V TSAQ+ A LL +L A VL+VGT AL EV AVGLR R+ Sbjct 63 AGVGVPASAAEVSTSAQAGAALLRERLPDDALVLVVGTAALEAEVQAVGLRTTRKNAPEV 122 Query 119 DAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATG 178 AVVQG S T WSDLAEA LA+R GA WVA N D TLP+ERG LPGNGSMVAALRTAT Sbjct 123 AAVVQGHSPDTCWSDLAEACLAVRGGAWWVACNADATLPSERGQLPGNGSMVAALRTATN 182 Query 179 MDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDA 238 +P VAGKP L+ A + +ALVVGDRLDTDI GA AAG SL+VLTGV +A Sbjct 183 REPEVAGKPEAPLLRTAARSVEANSALVVGDRLDTDIAGAAAAGYRSLVVLTGVATAKRL 242 Query 239 VYAEPVRRPTYIGHDLRSLHQDSKL--LAVAPQPGWQIDVGGGAVTVCANGDVDDLEFID 296 + A P RP Y+ DL L + L + P+PGW++ V G + V A D + +D Sbjct 243 LAAAPGERPDYLAVDLAVLTSEVNATDLEIGPRPGWRVTVDGDVLAVAAEDSGDQADRVD 302 Query 297 DGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLM 341 ++R + A W + + A DE+A AL W L+ Sbjct 303 ----LLRHLCHAAWSSSVTT-------VRAEDEQAERALSSWGLL 336 >gi|331697606|ref|YP_004333845.1| HAD-superfamily hydrolase [Pseudonocardia dioxanivorans CB1190] gi|326952295|gb|AEA25992.1| HAD-superfamily hydrolase, subfamily IIA [Pseudonocardia dioxanivorans CB1190] Length=352 Score = 262 bits (670), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 155/314 (50%), Positives = 207/314 (66%), Gaps = 10/314 (3%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQ--PTGGAVQSLSQVRS-RKLFVTNNASRSADEVAAHL 58 +S+ + HD LL+DLDGT++ G P + R R +VTNNASR EVAAHL Sbjct 5 RSLLKLHDVLLVDLDGTLYAGHDAIPHAVDAVVDAAARGVRTAYVTNNASRRPSEVAAHL 64 Query 59 CELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRP 118 ELGF AT +DV+TS+Q+ A LLA Q+ PGA VL++GT+ALA E A VGL+PVR Sbjct 65 GELGFPATTDDVMTSSQAGAALLAEQVDPGAAVLVLGTDALAEECALVGLKPVREAPGA- 123 Query 119 DAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATG 178 AV+QG + TGW +LAEA++ +RAG +WVA N D TLPT RG LPGNG+MV AL+ ATG Sbjct 124 VAVIQGHNPDTGWRNLAEASVVLRAGGIWVATNTDLTLPTPRGPLPGNGAMVTALKVATG 183 Query 179 MDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDA 238 ++P+VAGKP L+ EAV R RA LVVGDRLDTDIEG +AA LP+L+VLTG++ D Sbjct 184 LEPQVAGKPGLRLVREAVERSGARAGLVVGDRLDTDIEGGHAASLPTLLVLTGISGPSDV 243 Query 239 VYAEPVRRPTYIGHDLRSLHQDSKLLAV-APQPGWQIDVG-GGAVTVCANGDVDDLEFID 296 + A P +RP Y+ +L +L + + LA A +PGW ++ G V + +GD + Sbjct 244 LAAVPQQRPAYVAANLTALPRPAVELATDAVRPGWYVEAAPDGGVLLAGDGDGSP----E 299 Query 297 DGLSIVRAVASAVW 310 GL +R++ + W Sbjct 300 PGLDALRSLCAVHW 313 >gi|296393971|ref|YP_003658855.1| HAD-superfamily hydrolase, subfamily IIA [Segniliparus rotundus DSM 44985] gi|296181118|gb|ADG98024.1| HAD-superfamily hydrolase, subfamily IIA [Segniliparus rotundus DSM 44985] Length=277 Score = 262 bits (670), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 161/261 (62%), Positives = 195/261 (75%), Gaps = 0/261 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 M ++A++HD LL+DLDGT++ G +P AV++L R +VTNNASRS +VAA L Sbjct 1 MTTLAEQHDHLLLDLDGTLYHGPRPIESAVRALRGGRVPVTYVTNNASRSPADVAAALAA 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 +G+ A+ DV TSAQ+AA LLA +L GARVL+VG EALA+EV GL PVR F + P A Sbjct 61 MGYEASAHDVATSAQAAAELLAERLDEGARVLVVGAEALADEVRLRGLVPVRAFAEAPHA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S T WS LAEAALAIRAGALWVA NVDPTLPT+RGLLPGNGSMVAALRTAT + Sbjct 121 VVQGHSPQTDWSQLAEAALAIRAGALWVACNVDPTLPTDRGLLPGNGSMVAALRTATDQE 180 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P +AGKPA AL+ A+ R R+ LVVGDRLDTDI GANA GLPSL+VLTGV++ D + Sbjct 181 PEIAGKPAAALLQAALRRRPARSPLVVGDRLDTDIAGANAVGLPSLLVLTGVSTPEDVLA 240 Query 241 AEPVRRPTYIGHDLRSLHQDS 261 AE RPTY+ DL +L +D+ Sbjct 241 AEADLRPTYVAQDLSALGRDA 261 >gi|300787882|ref|YP_003768173.1| HAD family hydrolase [Amycolatopsis mediterranei U32] gi|299797396|gb|ADJ47771.1| HAD family hydrolase [Amycolatopsis mediterranei U32] gi|340529454|gb|AEK44659.1| HAD family hydrolase [Amycolatopsis mediterranei S699] Length=321 Score = 260 bits (664), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 149/275 (55%), Positives = 180/275 (66%), Gaps = 3/275 (1%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAHLCELGFT 64 +D +L DLDGTV+ G + GA +++ R FVTNNAS++ DEV AHL LG Sbjct 9 YDAVLFDLDGTVYHGTRVIPGAPETVRAAREHGTPVRFVTNNASKAPDEVVAHLTALGMP 68 Query 65 ATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQG 124 A +V TSAQ+ LL +L PGA VL+VGTE+LA EVA GL PVR D AVVQG Sbjct 69 AETGEVHTSAQAGVQLLKERLEPGAEVLVVGTESLAAEVAGAGLTPVRENGDGVRAVVQG 128 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVA 184 S W+ LAEA LAIRAGALWVA NVD TLP+ERGLLPGNGSMVAALRTAT ++P VA Sbjct 129 HSPDNTWAALAEACLAIRAGALWVACNVDATLPSERGLLPGNGSMVAALRTATEVEPLVA 188 Query 185 GKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPV 244 GKP P L A LVVGDRLDTDI GA AAG+ SL+VL+GV + + A P Sbjct 189 GKPQPLLFETAARSAGAERPLVVGDRLDTDIAGAVAAGIDSLVVLSGVATPKQLIEAVPA 248 Query 245 RRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGG 279 R TY+ DL +L + ++ L + P+PGW + GG Sbjct 249 ERATYLAKDLTALTEAAEDLKIGPRPGWTVSTEGG 283 >gi|291003071|ref|ZP_06561044.1| HAD family hydrolase [Saccharopolyspora erythraea NRRL 2338] Length=334 Score = 253 bits (646), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 148/287 (52%), Positives = 183/287 (64%), Gaps = 3/287 (1%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAHLCELGFT 64 HD +L+DLDGTV+ G + A S+ VR R + FVTNNA++S VA HL LG Sbjct 9 HDVVLLDLDGTVYRGGELVPSAAGSVQDVRGRGVKVRFVTNNAAKSPQAVADHLARLGLP 68 Query 65 ATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQG 124 +V TS+Q+ A +LA L GA+VL+VGT AL +EV VGL PVR + P AVVQG Sbjct 69 TEPVEVSTSSQAGAAVLAENLPEGAKVLVVGTSALESEVDKVGLVPVREVGEEPVAVVQG 128 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVA 184 S T W +LAEA LAIRAGALWVA N D TLPTERG LPGNG+MVAAL+ ATG P VA Sbjct 129 HSPDTAWKNLAEACLAIRAGALWVACNEDVTLPTERGELPGNGAMVAALKAATGQSPTVA 188 Query 185 GKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPV 244 GKP L+ AV AL+ GDRLDTDI GA AG+ SLMVLTGV++ D + A P Sbjct 189 GKPERPLLDNAVVSAGGTRALMAGDRLDTDIAGAVRAGMTSLMVLTGVHTPADLLAAGPD 248 Query 245 RRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDD 291 +RP ++ DL +LH+ VA QP W++ V + + +N DD Sbjct 249 KRPDHVAPDLSALHRPGAESVVAEQPEWKVRVDDTVLELASNSGKDD 295 >gi|134101756|ref|YP_001107417.1| HAD family hydrolase [Saccharopolyspora erythraea NRRL 2338] gi|133914379|emb|CAM04492.1| HAD-superfamily hydrolase, subfamily IIA [Saccharopolyspora erythraea NRRL 2338] Length=330 Score = 253 bits (645), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 148/287 (52%), Positives = 183/287 (64%), Gaps = 3/287 (1%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAHLCELGFT 64 HD +L+DLDGTV+ G + A S+ VR R + FVTNNA++S VA HL LG Sbjct 5 HDVVLLDLDGTVYRGGELVPSAAGSVQDVRGRGVKVRFVTNNAAKSPQAVADHLARLGLP 64 Query 65 ATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQG 124 +V TS+Q+ A +LA L GA+VL+VGT AL +EV VGL PVR + P AVVQG Sbjct 65 TEPVEVSTSSQAGAAVLAENLPEGAKVLVVGTSALESEVDKVGLVPVREVGEEPVAVVQG 124 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVA 184 S T W +LAEA LAIRAGALWVA N D TLPTERG LPGNG+MVAAL+ ATG P VA Sbjct 125 HSPDTAWKNLAEACLAIRAGALWVACNEDVTLPTERGELPGNGAMVAALKAATGQSPTVA 184 Query 185 GKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPV 244 GKP L+ AV AL+ GDRLDTDI GA AG+ SLMVLTGV++ D + A P Sbjct 185 GKPERPLLDNAVVSAGGTRALMAGDRLDTDIAGAVRAGMTSLMVLTGVHTPADLLAAGPD 244 Query 245 RRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDD 291 +RP ++ DL +LH+ VA QP W++ V + + +N DD Sbjct 245 KRPDHVAPDLSALHRPGAESVVAEQPEWKVRVDDTVLELASNSGKDD 291 >gi|258654199|ref|YP_003203355.1| Haloacid dehalogenase domain-containing protein hydrolase [Nakamurella multipartita DSM 44233] gi|258557424|gb|ACV80366.1| Haloacid dehalogenase domain protein hydrolase [Nakamurella multipartita DSM 44233] Length=366 Score = 252 bits (644), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 146/274 (54%), Positives = 183/274 (67%), Gaps = 4/274 (1%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQ---VRSRKLFVTNNASRSADEVAAH 57 M +AQ HD LL+DLDGTV+ G QP +L + + +R +FVTNNASR EVAA Sbjct 1 MTILAQAHDALLLDLDGTVYLGGQPIDHVAPALVRAGVLGARSVFVTNNASRPPAEVAAA 60 Query 58 LCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDR 117 L +G A +DV+TS Q+AA +LA + GA+VL++G L V GL+PVR ED Sbjct 61 LTSMGVAAEADDVLTSPQAAAVMLADRHPAGAKVLVIGAPWLEESVRQAGLQPVRLAEDE 120 Query 118 PDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTAT 177 P AVVQG S TGW +LAE +A+RAGA WVA NVD TLPT+RG+LPGNGSMVAAL AT Sbjct 121 PVAVVQGHSPDTGWRNLAEGCIALRAGADWVACNVDSTLPTDRGMLPGNGSMVAALVAAT 180 Query 178 GMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWD 237 G+ PRVAGKP L+ AV LVVGDRLDTDI A A PSLMVLTGV++A D Sbjct 181 GLHPRVAGKPERPLLDAAVRLVGSTRPLVVGDRLDTDIACAVGASTPSLMVLTGVSTASD 240 Query 238 AVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPG 271 + A+P +RPTY+ D+R L ++ + + + P PG Sbjct 241 LLAADPGQRPTYVAFDMRGLVEEDRAVRI-PGPG 273 >gi|319949195|ref|ZP_08023284.1| putative hydrolase [Dietzia cinnamea P4] gi|319437181|gb|EFV92212.1| putative hydrolase [Dietzia cinnamea P4] Length=332 Score = 250 bits (639), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 147/310 (48%), Positives = 198/310 (64%), Gaps = 6/310 (1%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 + ++A+ HD LL+DLDGT+ G +P GA +L + ++VTNNASRS ++ AAHL E Sbjct 3 VTTLAEGHDALLVDLDGTLIRGTEPIPGAADALERAGLPVVYVTNNASRSPEDTAAHLRE 62 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF+ ++V+TSAQ+A +L +APG+RVL+VG ++ G V +DRPDA Sbjct 63 LGFSTRPDEVMTSAQAAVVMLGDHVAPGSRVLVVGHDSFRQLAREGGYDVVLSADDRPDA 122 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 V+QGLS W+DLAE LAIR G W+A+NVD TLPTERGLLPGNGS+VAALR AT + Sbjct 123 VLQGLSRELTWADLAEGCLAIRRGVPWIASNVDTTLPTERGLLPGNGSLVAALRAATDRE 182 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKPA ++ A R LV+GDRLDTDIEGA AAG+P+LMVLTGV+ + Sbjct 183 PVVAGKPAAGVLRAAADRVGSTRPLVIGDRLDTDIEGAVAAGMPALMVLTGVHDQTHLLS 242 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A+P RRPT++ DL +L + + + + V G + + +G D L GL Sbjct 243 ADPHRRPTHLAPDLSALAEPADASRIPHTAEFDGAVEAGVLHL--SGVPDHLH----GLD 296 Query 301 IVRAVASAVW 310 + RAV + W Sbjct 297 LARAVIALAW 306 >gi|324998564|ref|ZP_08119676.1| predicted sugar phosphatase of HAD superfamily protein [Pseudonocardia sp. P1] Length=339 Score = 250 bits (639), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 162/311 (53%), Positives = 198/311 (64%), Gaps = 11/311 (3%) Query 4 IAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSR---KLFVTNNASRSADEVAAHLCE 60 + HD LL DLDGT++ G GAV+++ R ++VTNNASRS VA HL + Sbjct 5 LLSRHDVLLADLDGTLYRGPDVVPGAVEAVRSAELRGVPTVYVTNNASRSPSTVAGHLAD 64 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGF A DV TSAQ+ A +LA +L GA VL++GT ALA+EV GL P E DA Sbjct 65 LGFPARVADVRTSAQAGAAMLAERLPSGATVLVLGTPALADEVRERGLVPTGTGEGA-DA 123 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 VVQG S TGW L EA LAIRAGALWVA NVD TLPTERG LPGNGSMV +R A+G++ Sbjct 124 VVQGHSPDTGWRQLTEAVLAIRAGALWVATNVDLTLPTERGPLPGNGSMVQVVRNASGVE 183 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P VAGKP L+ E +GD LV+GDRLDTDIEGANA G PSLMVLTGV+ A D + Sbjct 184 PAVAGKPGARLLRE--GQGDADRPLVLGDRLDTDIEGANALGAPSLMVLTGVSGAADLLA 241 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS 300 A P RPTYIG DL +L + L + GW+ ++ G A+ + +G D E + D L Sbjct 242 APPALRPTYIGADLAALTRHPDELVPGARDGWRAEIDGDALVLSGDGHGD--EPVVDAL- 298 Query 301 IVRAVASAVWE 311 R + +A WE Sbjct 299 --RVLCAAAWE 307 >gi|54023962|ref|YP_118204.1| putative hydrolase [Nocardia farcinica IFM 10152] gi|54015470|dbj|BAD56840.1| putative hydrolase [Nocardia farcinica IFM 10152] Length=302 Score = 249 bits (635), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 146/255 (58%), Positives = 174/255 (69%), Gaps = 3/255 (1%) Query 8 HDCLLIDLDGTVFCGRQ--PTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTA 65 ++ LL+DLDGT++ G + + R +VTNNASR VAAHL ELGF A Sbjct 15 YEALLLDLDGTLYRGPVVIAGAPEALAAAATSQRLAYVTNNASRGPAVVAAHLAELGFPA 74 Query 66 TGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA-VVQG 124 EDVVTSAQ+A LLA +L PGA VL+VGT+ LA EV GL+P+RRF+ P A VVQG Sbjct 75 RAEDVVTSAQAAVRLLAERLEPGATVLVVGTDDLAAEVEEAGLKPIRRFDGAPPAAVVQG 134 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVA 184 S T W DLAEAA A+RAGALWVAAN D TLP ERGL PGNG+MVAAL+ AT P VA Sbjct 135 HSPQTAWPDLAEAAYAVRAGALWVAANTDRTLPNERGLAPGNGAMVAALQAATDRAPVVA 194 Query 185 GKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPV 244 GKP L+ +AVAR RAALVVGDRLDTDIEGA+ L SL+VLTGV++ + A P Sbjct 195 GKPYAPLLEDAVARVGTRAALVVGDRLDTDIEGADRVALDSLLVLTGVSTLDELRAAPPE 254 Query 245 RRPTYIGHDLRSLHQ 259 R PTY+ L +L+ Sbjct 255 RIPTYVAESLDALNH 269 >gi|254822055|ref|ZP_05227056.1| HAD-superfamily protein hydrolase, subfamily protein IIA [Mycobacterium intracellulare ATCC 13950] Length=160 Score = 238 bits (608), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 124/160 (78%), Positives = 136/160 (85%), Gaps = 0/160 (0%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE 60 MKS+AQE+DCLLIDLDGT F GRQPT GAV++L++VRSR FVTNNASRSADEVAAHL E Sbjct 1 MKSLAQEYDCLLIDLDGTAFRGRQPTEGAVEALAEVRSRAYFVTNNASRSADEVAAHLTE 60 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 LGFTAT +DV TSAQSAA LLA QL P + VLIVGTEALA E+ AVGLRPV +D P A Sbjct 61 LGFTATADDVATSAQSAARLLADQLPPDSPVLIVGTEALAGEITAVGLRPVHSNDDDPAA 120 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTER 160 VVQGLS+T GW +LAEAALAIRAGA WVAANVD TLPTER Sbjct 121 VVQGLSLTIGWPELAEAALAIRAGARWVAANVDLTLPTER 160 >gi|256832354|ref|YP_003161081.1| HAD-superfamily hydrolase, subfamily IIA [Jonesia denitrificans DSM 20603] gi|256685885|gb|ACV08778.1| HAD-superfamily hydrolase, subfamily IIA [Jonesia denitrificans DSM 20603] Length=342 Score = 237 bits (604), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 144/322 (45%), Positives = 188/322 (59%), Gaps = 12/322 (3%) Query 4 IAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRS---RKLFVTNNASRSADEVAAHLCE 60 ++Q + L+DLDG + G +P A L+ R R +FVTNNASR +VA L Sbjct 13 LSQRYPLALVDLDGVAYKGHEPINHASDGLNAARQHGMRLVFVTNNASREPQDVAQQLTS 72 Query 61 LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA 120 L A +DV+T+AQ+ A LL + PGA+VL++G L V G V +D P A Sbjct 73 LDIPAHSDDVMTAAQACARLLTQHVEPGAKVLVIGGAGLRTAVHEAGYTIVESADDNPIA 132 Query 121 VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD 180 V QG + T GW DLAEAA A+ AGAL VA+N+D +LPT RG PGNGS+V A++ ATG++ Sbjct 133 VAQGFAPTLGWKDLAEAAYAVTAGALHVASNLDLSLPTARGFAPGNGSLVGAVKAATGVE 192 Query 181 PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY 240 P AGKP+PA+ A+ R ALV+GDRLDTD+ GA A GL L VLTGV++ DA+ Sbjct 193 PLSAGKPSPAMYHMAIERAGASTALVIGDRLDTDLAGARAGGLHGLHVLTGVSTIRDAIN 252 Query 241 AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANG----DVDDLEFID 296 A P+ RP Y+ DLR+L + AV + GW + G AV V + + DD E Sbjct 253 ASPIERPHYLACDLRAL--TTTHPAVTQRNGWWV-CGASAVRVVDSALEVWESDDSEGSP 309 Query 297 DGLSIVRAVASAVWEARAADLH 318 DGL RA A W AD H Sbjct 310 DGLDPARAACVAAW--NYADTH 329 >gi|317507357|ref|ZP_07965093.1| HAD-superfamily hydrolase [Segniliparus rugosus ATCC BAA-974] gi|316254354|gb|EFV13688.1| HAD-superfamily hydrolase [Segniliparus rugosus ATCC BAA-974] Length=286 Score = 234 bits (597), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 154/257 (60%), Positives = 181/257 (71%), Gaps = 9/257 (3%) Query 17 GTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATGEDVVTSAQS 76 GT++ G +P AV++L V +VTNNASRS +VAA L +G+ A EDVVTSAQ+ Sbjct 17 GTLYHGPRPIDSAVRALRDVPGPVTYVTNNASRSPRDVAAALSGMGYAAADEDVVTSAQA 76 Query 77 AAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRP---------DAVVQGLSM 127 AA LLA +L PGA VL+VG +AL +E+ + GL PVR+F D P V QG S Sbjct 77 AAELLAAELDPGASVLVVGAQALEDELRSRGLVPVRQFADLPVSGGGAPRSSGVAQGHSP 136 Query 128 TTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKP 187 T W LAEAALAIRAGALWVA N+DPTLPTERGLLPGNGSMVAALRTAT DP VAGKP Sbjct 137 QTDWPQLAEAALAIRAGALWVACNIDPTLPTERGLLPGNGSMVAALRTATDQDPLVAGKP 196 Query 188 APALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRP 247 A LM A+ R +A LVVGDRLDTDI GANA GLPSL+VLTGV++ DA+ AE RP Sbjct 197 AAPLMAAALRRVPAKAPLVVGDRLDTDIAGANAVGLPSLLVLTGVSTVADALAAEAALRP 256 Query 248 TYIGHDLRSLHQDSKLL 264 TY+ DL +LHQ + L Sbjct 257 TYVAADLSALHQSPEPL 273 >gi|257068536|ref|YP_003154791.1| putative sugar phosphatase of HAD superfamily [Brachybacterium faecium DSM 4810] gi|256559354|gb|ACU85201.1| predicted sugar phosphatase of HAD superfamily [Brachybacterium faecium DSM 4810] Length=343 Score = 234 bits (596), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 138/257 (54%), Positives = 168/257 (66%), Gaps = 7/257 (2%) Query 3 SIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRS---RKLFVTNNASRSADEVAAHLC 59 S+ +D LL DLDGT+ G QP A +S+ + R+ +F TNNASR+ + A HL Sbjct 8 SLLDLYDALLFDLDGTLMHGAQPIPHAAESVEKARAAGRSVVFATNNASRTPQQAAEHLA 67 Query 60 ELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPD 119 +G A E+ VTS Q A+ LLA +L PGA+VL+VG +LA +V GL PV D PD Sbjct 68 VVGIPARPEEFVTSPQVASRLLADRLDPGAKVLVVGGPSLAAQVREAGLTPVE--TDEPD 125 Query 120 --AVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTAT 177 AVVQG S WS LAE A AIR GA W+A NVD TLPTERGL PGNGS+VAA+R AT Sbjct 126 VVAVVQGWSPDLDWSRLAEGAYAIRHGAYWMATNVDATLPTERGLAPGNGSLVAAVRHAT 185 Query 178 GMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWD 237 G +P VAGKP P + A R L++GDRLDTDIEGA AG+ SL+VLTGV+ Sbjct 186 GAEPAVAGKPEPGMFEVAAREHRARRPLIIGDRLDTDIEGAVRAGMDSLLVLTGVDGIEA 245 Query 238 AVYAEPVRRPTYIGHDL 254 A+ AEPVRRPT+I DL Sbjct 246 ALRAEPVRRPTFILPDL 262 >gi|271967341|ref|YP_003341537.1| sugar phosphatase of the HAD superfamily-like protein [Streptosporangium roseum DSM 43021] gi|270510516|gb|ACZ88794.1| sugar phosphatase of the HAD superfamily-like protein [Streptosporangium roseum DSM 43021] Length=336 Score = 234 bits (596), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 136/262 (52%), Positives = 174/262 (67%), Gaps = 3/262 (1%) Query 1 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKL---FVTNNASRSADEVAAH 57 ++++ +D LL+DLDG V+ GR GA +SL + R + +VTNNASR+ +A H Sbjct 3 IQTLIDPYDTLLLDLDGVVYLGRDAVPGAPESLREAAGRGVRLAYVTNNASRTPGAIAEH 62 Query 58 LCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDR 117 L LG AT EDVVTSAQ+AA L+A ++APGA VL VG L + + A GLRPV D Sbjct 63 LSALGAPATPEDVVTSAQAAARLVAERVAPGAAVLTVGGMGLRSALRAHGLRPVSTAMDG 122 Query 118 PDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTAT 177 AVVQG++ + L+E ALA+R GAL+VAAN D T+PT RG LPGNG+M + TAT Sbjct 123 AVAVVQGIAPGLSYGLLSEGALAVRQGALFVAANADSTMPTSRGELPGNGAMTRVIATAT 182 Query 178 GMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWD 237 G++P VAGKP P L E++ R R LVVGDRLDTDIEGA AG+ SL+VLTGV S D Sbjct 183 GVEPIVAGKPEPPLHRESMLRTGSRRPLVVGDRLDTDIEGATNAGVDSLLVLTGVASPLD 242 Query 238 AVYAEPVRRPTYIGHDLRSLHQ 259 + A P RPTY+ L +LH+ Sbjct 243 LLTAGPRHRPTYVAAGLSALHR 264 >gi|334336861|ref|YP_004542013.1| HAD-superfamily hydrolase, subfamily IIA [Isoptericola variabilis 225] gi|334107229|gb|AEG44119.1| HAD-superfamily hydrolase, subfamily IIA [Isoptericola variabilis 225] Length=337 Score = 233 bits (593), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 134/275 (49%), Positives = 171/275 (63%), Gaps = 3/275 (1%) Query 2 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRS---RKLFVTNNASRSADEVAAHL 58 + +A+E D L+DLDG + G P A +SL R+ R +FVTNNASR ++VA L Sbjct 10 RPLAEEFDLALVDLDGVAYRGHLPIEHAAESLGAARAAGMRLVFVTNNASREPEDVAGQL 69 Query 59 CELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRP 118 L A+ E+V+T+AQ+ A LL +L PGARVL+VG L V A G V +DRP Sbjct 70 TGLDIPASPEEVMTAAQACAALLRTRLEPGARVLVVGGRGLVTAVEAQGFEVVTSADDRP 129 Query 119 DAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATG 178 DAV QG + W LAEAA A+ AGA VA+N+D +LPT RG PGNG++V A+ ATG Sbjct 130 DAVAQGYAPEVAWPQLAEAAYAVEAGAWHVASNLDLSLPTARGFAPGNGALVGAVVAATG 189 Query 179 MDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDA 238 + P AGKP+P + AV R R LVVGDRLDTD+ GA A P L VLTGV+SA DA Sbjct 190 VTPDSAGKPSPTMYRLAVERVGARRPLVVGDRLDTDLAGARAGSYPGLHVLTGVSSARDA 249 Query 239 VYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQ 273 V AEP RP ++G DLR+LH+ + P W+ Sbjct 250 VLAEPGLRPDFVGADLRALHEVHPVPVEGPDGWWE 284 >gi|296140087|ref|YP_003647330.1| HAD-superfamily hydrolase [Tsukamurella paurometabola DSM 20162] gi|296028221|gb|ADG78991.1| HAD-superfamily hydrolase, subfamily IIA [Tsukamurella paurometabola DSM 20162] Length=316 Score = 232 bits (591), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 141/271 (53%), Positives = 172/271 (64%), Gaps = 3/271 (1%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATG 67 +D LL+DLDGTV+ G GA +L+ + +VTNNASR+ +VA HL +LGF A Sbjct 9 YDLLLVDLDGTVYAGPVAIPGAADALTGLPVT--YVTNNASRAPSDVAHHLRDLGFAAPD 66 Query 68 EDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSM 127 + VVTSAQ+ A LLA + P L+VG AL EV GL PV E+ AVVQG + Sbjct 67 DSVVTSAQAGARLLATLVPPATPTLVVGAPALRTEVIERGLVPVETAEEA-RAVVQGHNP 125 Query 128 TTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKP 187 TGW+ L+EAALAIRAGA WVA N D TLPTERGL+ GNGSMVAA+ ATG PRVAGKP Sbjct 126 ETGWARLSEAALAIRAGATWVATNTDATLPTERGLMVGNGSMVAAVAHATGAVPRVAGKP 185 Query 188 APALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRP 247 ++ +AVA + LVVGDRLDTDIEG NA G+ + +VLTGVN D + A +P Sbjct 186 GTPILADAVAAAGATSPLVVGDRLDTDIEGGNALGVDTYLVLTGVNDVADVIAAPDAHQP 245 Query 248 TYIGHDLRSLHQDSKLLAVAPQPGWQIDVGG 278 TYI L LH + P+PGW V G Sbjct 246 TYIADTLAGLHAPAAQSLPGPRPGWSAAVEG 276 >gi|237785440|ref|YP_002906145.1| hypothetical protein ckrop_0848 [Corynebacterium kroppenstedtii DSM 44385] gi|237758352|gb|ACR17602.1| conserved hypothetical protein [Corynebacterium kroppenstedtii DSM 44385] Length=367 Score = 230 bits (587), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 125/270 (47%), Positives = 175/270 (65%), Gaps = 2/270 (0%) Query 9 DCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRK--LFVTNNASRSADEVAAHLCELGFTAT 66 D LL+DLDGTV+ G +P AV +L++ S ++TNNASRS VA L E+G A+ Sbjct 21 DALLLDLDGTVYHGARPIPEAVSALNKAHSHVGLKYITNNASRSPSAVAEALQEMGIPAS 80 Query 67 GEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLS 126 ++V+TSAQ+ LL ++ G+RV+++G+++L V G V +D+P AV+QG + Sbjct 81 EDEVLTSAQAGVTLLTSKIPAGSRVIVLGSDSLKELVNEAGFSVVTSADDQPAAVIQGHA 140 Query 127 MTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGK 186 TTGW ++EAALAI GA++VA N+D TLPTERGL GNGSM+AA+ TATG+ P AGK Sbjct 141 TTTGWPQMSEAALAINNGAVYVATNMDTTLPTERGLTVGNGSMIAAVTTATGVTPDSAGK 200 Query 187 PAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR 246 PA + T+A L VGDRL+TDI G AAG+PSLMV+TG++ D + A+P R Sbjct 201 PAGDMFTQAAEELHSDRPLAVGDRLNTDIAGGVAAGIPSLMVITGISGHTDLLAADPAER 260 Query 247 PTYIGHDLRSLHQDSKLLAVAPQPGWQIDV 276 PTYI D+ +L P+ GW+ ++ Sbjct 261 PTYIATDMMALFDPIDRSTPGPKQGWKAEL 290 >gi|315506774|ref|YP_004085661.1| HAD superfamily hydrolase [Micromonospora sp. L5] gi|315413393|gb|ADU11510.1| HAD-superfamily hydrolase, subfamily IIA [Micromonospora sp. L5] Length=356 Score = 226 bits (576), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 137/278 (50%), Positives = 173/278 (63%), Gaps = 7/278 (2%) Query 8 HDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRK---LFVTNNASRSADEVAAHLCELGFT 64 + ++ DLDG ++ +P GAV+++ ++ + + TNNASR + EVA L +G Sbjct 30 YSLVVFDLDGVIYLIDRPIPGAVEAVGRLHAEGRAVAYATNNASRRSSEVADLLTGMGVA 89 Query 65 ATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQG 124 A +V+TSA + A LL +L GA VL+VG EAL E+ AVGLRPV ++ P AV QG Sbjct 90 ARPAEVLTSAAATAELLRDRLPEGAPVLVVGAEALRAELRAVGLRPVSTADEEPAAVAQG 149 Query 125 LSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPR-V 183 GWSDLAEA+LA+RAGA W A N D TLP+ RG LPGNGS+VA LRTA G DP V Sbjct 150 YGPQVGWSDLAEASLAVRAGAPWYATNTDRTLPSPRGPLPGNGSLVAVLRTALGRDPDVV 209 Query 184 AGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEP 243 GKP PAL T A R LVVGDRLDTDIEGA AGL SL+VLTGV+ A + + A Sbjct 210 VGKPEPALFTTAARRAGTGRTLVVGDRLDTDIEGARRAGLDSLLVLTGVSDAAELLAAPE 269 Query 244 VRRPTYIGHDLRSLHQDSKLLAV---APQPGWQIDVGG 278 RRP Y+ DL L + ++AV A GW + G Sbjct 270 ERRPAYVSFDLAGLFDPAAVVAVPGRAADDGWSVTEAG 307 Lambda K H 0.318 0.132 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 657685396884 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40