BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1694 Length=268 Score E Sequences producing significant alignments: (Bits) Value gi|15608832|ref|NP_216210.1| cytotoxin/hemolysin TlyA [Mycobacte... 521 4e-146 gi|339631748|ref|YP_004723390.1| hypothetical protein MAF_17110 ... 520 1e-145 gi|240170143|ref|ZP_04748802.1| hypothetical protein MkanA1_1257... 422 2e-116 gi|289447308|ref|ZP_06437052.1| LOW QUALITY PROTEIN: inorganic p... 422 2e-116 gi|296164594|ref|ZP_06847161.1| cytotoxin/hemolysin [Mycobacteri... 419 2e-115 gi|254821088|ref|ZP_05226089.1| TlyA [Mycobacterium intracellula... 412 3e-113 gi|118617311|ref|YP_905643.1| cytotoxin/hemolysin, TlyA [Mycobac... 407 7e-112 gi|183982514|ref|YP_001850805.1| cytotoxin/hemolysin, TlyA [Myco... 406 2e-111 gi|15827705|ref|NP_301968.1| cytotoxin/hemolysin [Mycobacterium ... 402 2e-110 gi|118469022|ref|YP_888048.1| hemolysin A [Mycobacterium smegmat... 400 8e-110 gi|41407499|ref|NP_960335.1| TlyA [Mycobacterium avium subsp. pa... 397 6e-109 gi|342860728|ref|ZP_08717378.1| TlyA [Mycobacterium colombiense ... 395 2e-108 gi|118462925|ref|YP_882261.1| hemolysin A [Mycobacterium avium 1... 395 3e-108 gi|467142|gb|AAA50906.1| u0247a [Mycobacterium leprae] 394 6e-108 gi|108799917|ref|YP_640114.1| hemolysin A [Mycobacterium sp. MCS... 394 1e-107 gi|120404265|ref|YP_954094.1| hemolysin A [Mycobacterium vanbaal... 392 3e-107 gi|333990490|ref|YP_004523104.1| cytotoxin/hemolysin TlyA [Mycob... 385 3e-105 gi|145224093|ref|YP_001134771.1| hemolysin A [Mycobacterium gilv... 382 3e-104 gi|169629445|ref|YP_001703094.1| cytotoxin/hemolysin TlyA [Mycob... 344 6e-93 gi|333919193|ref|YP_004492774.1| putative hemolysin [Amycolicico... 319 2e-85 gi|226306754|ref|YP_002766714.1| hemolysin [Rhodococcus erythrop... 318 5e-85 gi|111017953|ref|YP_700925.1| hemolysin [Rhodococcus jostii RHA1... 317 2e-84 gi|226360083|ref|YP_002777861.1| hemolysin [Rhodococcus opacus B... 316 2e-84 gi|229494834|ref|ZP_04388588.1| hemolysin A [Rhodococcus erythro... 313 1e-83 gi|284991439|ref|YP_003409993.1| hemolysin A [Geodermatophilus o... 310 1e-82 gi|300787880|ref|YP_003768171.1| hemolysin-like protein [Amycola... 310 2e-82 gi|302528025|ref|ZP_07280367.1| ribosomal RNA large subunit meth... 308 6e-82 gi|343928398|ref|ZP_08767846.1| hemolysin [Gordonia alkanivorans... 306 1e-81 gi|72162433|ref|YP_290090.1| hemolysin A [Thermobifida fusca YX]... 306 3e-81 gi|262202727|ref|YP_003273935.1| hemolysin A [Gordonia bronchial... 305 4e-81 gi|296140085|ref|YP_003647328.1| hemolysin A [Tsukamurella pauro... 300 1e-79 gi|54023964|ref|YP_118206.1| putative cytotoxin/hemolysin [Nocar... 300 1e-79 gi|325674266|ref|ZP_08153955.1| cytotoxin/hemolysin [Rhodococcus... 300 1e-79 gi|296269986|ref|YP_003652618.1| hemolysin A [Thermobispora bisp... 298 6e-79 gi|284033301|ref|YP_003383232.1| hemolysin A [Kribbella flavida ... 296 1e-78 gi|256379446|ref|YP_003103106.1| hemolysin A [Actinosynnema miru... 293 1e-77 gi|271967338|ref|YP_003341534.1| hemolysin A [Streptosporangium ... 293 2e-77 gi|291003073|ref|ZP_06561046.1| putative cytotoxin/hemolysin [Sa... 293 2e-77 gi|258654197|ref|YP_003203353.1| hemolysin A [Nakamurella multip... 293 2e-77 gi|336179106|ref|YP_004584481.1| hemolysin A [Frankia symbiont o... 292 3e-77 gi|172040777|ref|YP_001800491.1| hypothetical protein cur_1097 [... 290 1e-76 gi|302546497|ref|ZP_07298839.1| cytotoxin/hemolysin [Streptomyce... 290 2e-76 gi|294628609|ref|ZP_06707169.1| cytotoxin/hemolysin [Streptomyce... 290 2e-76 gi|331697604|ref|YP_004333843.1| hemolysin A [Pseudonocardia dio... 289 3e-76 gi|320011585|gb|ADW06435.1| hemolysin A [Streptomyces flavogrise... 289 3e-76 gi|337764997|emb|CCB73706.1| putative methyltransferase with RNA... 288 4e-76 gi|289772501|ref|ZP_06531879.1| rRNA methylase [Streptomyces liv... 288 4e-76 gi|328881468|emb|CCA54707.1| RNA binding methyltransferase FtsJ ... 288 5e-76 gi|21220274|ref|NP_626053.1| hypothetical protein SCO1782 [Strep... 288 7e-76 gi|297561969|ref|YP_003680943.1| hemolysin A [Nocardiopsis dasso... 286 2e-75 >gi|15608832|ref|NP_216210.1| cytotoxin/hemolysin TlyA [Mycobacterium tuberculosis H37Rv] gi|15841151|ref|NP_336188.1| cytotoxin/hemolysin [Mycobacterium tuberculosis CDC1551] gi|31792880|ref|NP_855373.1| cytotoxin [Mycobacterium bovis AF2122/97] 75 more sequence titles Length=268 Score = 521 bits (1342), Expect = 4e-146, Method: Compositional matrix adjust. Identities = 267/268 (99%), Positives = 268/268 (100%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER Sbjct 1 MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW Sbjct 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL Sbjct 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLRTQTDRALSAKGLEDAVHRAISEGP Sbjct 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 >gi|339631748|ref|YP_004723390.1| hypothetical protein MAF_17110 [Mycobacterium africanum GM041182] gi|339331104|emb|CCC26782.1| CYTOTOXIN|haemolysin homologue TLYA [Mycobacterium africanum GM041182] Length=268 Score = 520 bits (1338), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 266/268 (99%), Positives = 268/268 (100%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER Sbjct 1 MARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW Sbjct 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASR+ADIVPL Sbjct 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRNADIVPL 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLRTQTDRALSAKGLEDAVHRAISEGP Sbjct 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 >gi|240170143|ref|ZP_04748802.1| hypothetical protein MkanA1_12573 [Mycobacterium kansasii ATCC 12478] Length=269 Score = 422 bits (1086), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 216/268 (81%), Positives = 232/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRARVD ELVRRGLARSR QAAELI AGKVRIDGLP VKPATAV+ + ALTV D R Sbjct 1 MARRARVDVELVRRGLARSRHQAAELIEAGKVRIDGLPVVKPATAVAPSAALTVAVDGAR 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AFA+ V GRRCLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFAVPVQGRRCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLRNDPRV V+ERTN R ++PEAIGG VDL+VADLSFISL TVLPAL+ CAS ADIVP+ Sbjct 121 SLRNDPRVAVVERTNVRDVSPEAIGGSVDLIVADLSFISLGTVLPALIDCASPGADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVV DPQLRA +VLAV+RRA ELGWH+VGV ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVSDPQLRADAVLAVSRRADELGWHTVGVAASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTDR L+ L DAV RA S GP Sbjct 241 LWLRAQTDRWLAGDELVDAVRRATSMGP 268 >gi|289447308|ref|ZP_06437052.1| LOW QUALITY PROTEIN: inorganic polyphosphate/ATP-NAD kinase ppnK [Mycobacterium tuberculosis CPHL_A] gi|289420266|gb|EFD17467.1| LOW QUALITY PROTEIN: inorganic polyphosphate/ATP-NAD kinase ppnK [Mycobacterium tuberculosis CPHL_A] Length=216 Score = 422 bits (1086), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 214/214 (100%), Positives = 214/214 (100%), Gaps = 0/214 (0%) Query 55 VTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVG 114 VTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVG Sbjct 3 VTDSERAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVG 62 Query 115 YGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRD 174 YGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRD Sbjct 63 YGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRD 122 Query 175 ADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPS 234 ADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPS Sbjct 123 ADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPS 182 Query 235 GNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 GNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP Sbjct 183 GNVEYFLWLRTQTDRALSAKGLEDAVHRAISEGP 216 >gi|296164594|ref|ZP_06847161.1| cytotoxin/hemolysin [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900013|gb|EFG79452.1| cytotoxin/hemolysin [Mycobacterium parascrofulaceum ATCC BAA-614] Length=269 Score = 419 bits (1077), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 217/268 (81%), Positives = 232/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAG+V IDGLPA KP TAV+ T ALTV D ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGRVSIDGLPARKPGTAVAVTAALTVADDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF I VAGRRCLDAGASTGGFTEVLL RGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFGIPVAGRRCLDAGASTGGFTEVLLHRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR DPRVVV+ERTN R L+PEAIGG VDL+VADLSFISLA+VLPAL GCAS ADIVP+ Sbjct 121 SLRCDPRVVVVERTNVRDLSPEAIGGPVDLIVADLSFISLASVLPALAGCASPTADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKG+VGPGGVVHDP LRA +VLAVARRA ELGWH+VG ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGRVGPGGVVHDPGLRADAVLAVARRAGELGWHTVGATASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTDR L L AV RA+ EGP Sbjct 241 LWLRAQTDRGLVDDELVAAVQRAVKEGP 268 >gi|254821088|ref|ZP_05226089.1| TlyA [Mycobacterium intracellulare ATCC 13950] Length=269 Score = 412 bits (1058), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 213/268 (80%), Positives = 230/268 (86%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAGKV IDG+PA KP TAV+ T ALTV TD ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGKVSIDGMPARKPGTAVAVTAALTVATDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF I+VAGRRCLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFGISVAGRRCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+D RVVV+ERTN R LTPEAIGG DLVVADLSFISLATVLPAL GCA+ +ADIVP+ Sbjct 121 SLRSDARVVVVERTNVRDLTPEAIGGPADLVVADLSFISLATVLPALAGCAAPNADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVG GGVVHDP LRA +V +VARRA ELGWH+V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGAGGVVHDPGLRADAVTSVARRAAELGWHTVDVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR Q DR L+ L AV A+ GP Sbjct 241 LRLRAQADRPLAGDALVAAVRHAVESGP 268 >gi|118617311|ref|YP_905643.1| cytotoxin/hemolysin, TlyA [Mycobacterium ulcerans Agy99] gi|7340781|emb|CAB83047.1| putative haemolysin [Mycobacterium ulcerans] gi|118569421|gb|ABL04172.1| cytotoxin/hemolysin, TlyA [Mycobacterium ulcerans Agy99] Length=281 Score = 407 bits (1047), Expect = 7e-112, Method: Compositional matrix adjust. Identities = 218/268 (82%), Positives = 233/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARR RVDAELVRRGLARSRQQAAELI AGKVRIDGLPAVKPATAV+ T ALTV DSER Sbjct 1 MARRTRVDAELVRRGLARSRQQAAELISAGKVRIDGLPAVKPATAVAATAALTVAADSER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF I V GRRCLDAGASTGGFTEVLLDRGAA VVAADVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFGIDVHGRRCLDAGASTGGFTEVLLDRGAAEVVAADVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR DPRV+V+ERTN R L+P AIGG+VDLVVADLSFISL TVLPAL CA ADIVP+ Sbjct 121 SLRTDPRVIVIERTNVRDLSPAAIGGQVDLVVADLSFISLTTVLPALAACALPHADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVG GGVV DP LRA +VL+VARRA ELGWH+VGV ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGAGGVVQDPALRAGAVLSVARRAGELGWHTVGVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTDR LS L DA+ A++EGP Sbjct 241 LWLRAQTDRPLSDDTLSDAIQTAVAEGP 268 >gi|183982514|ref|YP_001850805.1| cytotoxin/hemolysin, TlyA [Mycobacterium marinum M] gi|183175840|gb|ACC40950.1| cytotoxin/hemolysin, TlyA [Mycobacterium marinum M] Length=281 Score = 406 bits (1043), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 217/268 (81%), Positives = 233/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARR RVDAELVRRGLARSRQQAAELI AGKVRIDGLPAVKPATAV+ T ALTV DSER Sbjct 1 MARRTRVDAELVRRGLARSRQQAAELISAGKVRIDGLPAVKPATAVAATAALTVAADSER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF I V GRRCLDAGASTGGFT+VLLDRGAA VVAADVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFGIDVHGRRCLDAGASTGGFTDVLLDRGAAEVVAADVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR DPRV+V+ERTN R L+P AIGG+VDLVVADLSFISL TVLPAL CA ADIVP+ Sbjct 121 SLRTDPRVIVIERTNVRDLSPAAIGGQVDLVVADLSFISLTTVLPALAACALPHADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVG GGVV DP LRA +VL+VARRA ELGWH+VGV ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGAGGVVQDPALRAGAVLSVARRAGELGWHTVGVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTDR LS L DA+ A++EGP Sbjct 241 LWLRAQTDRPLSDDTLSDAIQTAVAEGP 268 >gi|15827705|ref|NP_301968.1| cytotoxin/hemolysin [Mycobacterium leprae TN] gi|221230182|ref|YP_002503598.1| cytotoxin/hemolysin [Mycobacterium leprae Br4923] gi|2065225|emb|CAB08287.1| hypothetical protein MLC1351.14c [Mycobacterium leprae] gi|13093256|emb|CAC31739.1| cytotoxin/hemolysin [Mycobacterium leprae] gi|219933289|emb|CAR71453.1| cytotoxin/hemolysin [Mycobacterium leprae Br4923] Length=269 Score = 402 bits (1034), Expect = 2e-110, Method: Compositional matrix adjust. Identities = 210/268 (79%), Positives = 226/268 (85%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARR RVD ELVRRGLARSRQQAA+LI AGKV IDGLPAVKP+TAV+ TT LTV D ER Sbjct 1 MARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +WVSRGAHKL+GAL+ F I VAGR CLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 SWVSRGAHKLMGALDTFGIPVAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 S+R DPRV+V+ERTN L+PE IGG VDLVVADLSFISLATVL AL GCA ADIVP+ Sbjct 121 SVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISLATVLSALAGCALPSADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVV D +LRA SVLAVARRA ELGW ++ V AS LPG SGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTD LS GLE AV RAI+EGP Sbjct 241 LWLRAQTDLELSTDGLEAAVQRAIAEGP 268 >gi|118469022|ref|YP_888048.1| hemolysin A [Mycobacterium smegmatis str. MC2 155] gi|118170309|gb|ABK71205.1| hemolysin A [Mycobacterium smegmatis str. MC2 155] Length=269 Score = 400 bits (1029), Expect = 8e-110, Method: Compositional matrix adjust. Identities = 205/268 (77%), Positives = 224/268 (84%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRARVDAELVRRGLARSRQQAAELIGAG+VRIDG+PA KPATAVS LTV+ ER Sbjct 1 MARRARVDAELVRRGLARSRQQAAELIGAGRVRIDGMPAAKPATAVSVDANLTVIESDER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF ++V GRRCLDAGASTGGFTEVLLDRGAA VVAADVGYGQLAW Sbjct 61 TWVSRGAHKLIGALDAFGLSVEGRRCLDAGASTGGFTEVLLDRGAAEVVAADVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+DPRV VLERTN R LTPEAIGG V ++VADLSFISLATVLPAL CA RDADIVP+ Sbjct 121 SLRSDPRVHVLERTNVRDLTPEAIGGPVQMIVADLSFISLATVLPALTACAVRDADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGK +VG GGVV DP+LR +V V R+A L WH+V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKDRVGAGGVVSDPELRIDAVCTVGRKAAALQWHAVDVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR +TD L LE AV RA+ EGP Sbjct 241 LRLRAETDSPLEGDALEAAVRRAVEEGP 268 >gi|41407499|ref|NP_960335.1| TlyA [Mycobacterium avium subsp. paratuberculosis K-10] gi|254775529|ref|ZP_05217045.1| TlyA [Mycobacterium avium subsp. avium ATCC 25291] gi|41395852|gb|AAS03718.1| TlyA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457853|gb|EGO36847.1| hemolysin A [Mycobacterium avium subsp. paratuberculosis S397] Length=269 Score = 397 bits (1021), Expect = 6e-109, Method: Compositional matrix adjust. Identities = 214/268 (80%), Positives = 232/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAGKV IDG+PA KP TAV+ T ALTV D ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGKVSIDGMPARKPGTAVAVTAALTVAADGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF IAVAGRRCLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLLGALDAFEIAVAGRRCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+D RVVV+ERTN R LTPEAIGG DLVVADLSFISL TVLPAL GCA+ ADIVP+ Sbjct 121 SLRSDARVVVVERTNVRDLTPEAIGGPADLVVADLSFISLCTVLPALAGCAAPHADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVV+DP+LRA++VL+VARRA ELGWH V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVNDPELRAQAVLSVARRADELGWHPVDVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR +TDR L+ L AV RA+ GP Sbjct 241 LRLRARTDRPLAGDALCRAVRRAVESGP 268 >gi|342860728|ref|ZP_08717378.1| TlyA [Mycobacterium colombiense CECT 3035] gi|342131752|gb|EGT85009.1| TlyA [Mycobacterium colombiense CECT 3035] Length=269 Score = 395 bits (1016), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 214/268 (80%), Positives = 230/268 (86%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAGKV IDG+PA KP TAV+ T ALTV D ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGKVSIDGMPARKPGTAVAVTAALTVAEDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AFAIAVAGRRCLDAGASTGGFTEVLLDRGA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDAFAIAVAGRRCLDAGASTGGFTEVLLDRGATEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+D RVVV+ERTN R LTP+AIGGR DLVVADLSFISL+TVLPAL GCA+ DADIVP+ Sbjct 121 SLRSDARVVVVERTNVRDLTPDAIGGRADLVVADLSFISLSTVLPALAGCAAPDADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKG VG GGVVHDP+LRA +VLAVA RA ELGWH V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGLVGAGGVVHDPELRAGAVLAVAARAAELGWHPVDVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR QTDR L+ L AV A+ GP Sbjct 241 LRLRAQTDRPLAGDELVSAVRSAVESGP 268 >gi|118462925|ref|YP_882261.1| hemolysin A [Mycobacterium avium 104] gi|118164212|gb|ABK65109.1| hemolysin A [Mycobacterium avium 104] Length=269 Score = 395 bits (1016), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 213/268 (80%), Positives = 232/268 (87%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAG+V IDG+PA KP TAV+ T ALTV D ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGRVSIDGMPARKPGTAVAVTAALTVAADGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+AF IAVAGRRCLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLLGALDAFEIAVAGRRCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+D RVVV+ERTN R LTPEAIGG DLVVADLSFISL TVLPAL GCA+ ADIVP+ Sbjct 121 SLRSDARVVVVERTNVRDLTPEAIGGPADLVVADLSFISLCTVLPALAGCAAPHADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVV+DP+LRA++VL+VARRA ELGWH V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKGQVGPGGVVNDPELRAQAVLSVARRADELGWHPVDVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR +TDR L+ L AV RA+ GP Sbjct 241 LRLRARTDRPLAGDALCRAVRRAVESGP 268 >gi|467142|gb|AAA50906.1| u0247a [Mycobacterium leprae] Length=268 Score = 394 bits (1013), Expect = 6e-108, Method: Compositional matrix adjust. Identities = 208/268 (78%), Positives = 224/268 (84%), Gaps = 1/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARR RVD ELVRRGLARSRQQAA+LI AGKV IDGLPAVKP+TAV+ TT LTV D ER Sbjct 1 MARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +WV GAHKL+GAL+ F I VAGR CLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 SWVC-GAHKLMGALDTFGIPVAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW 119 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 S+R DPRV+V+ERTN L+PE IGG VDLVVADLSFISLATVL AL GCA ADIVP+ Sbjct 120 SVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISLATVLSALAGCALPSADIVPM 179 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKGQVGPGGVV D +LRA SVLAVARRA ELGW ++ V AS LPG SGNVEYF Sbjct 180 VKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF 239 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR QTD LS GLE AV RAI+EGP Sbjct 240 LWLRAQTDLELSTDGLEAAVQRAIAEGP 267 >gi|108799917|ref|YP_640114.1| hemolysin A [Mycobacterium sp. MCS] gi|119869027|ref|YP_938979.1| hemolysin A [Mycobacterium sp. KMS] gi|126435545|ref|YP_001071236.1| hemolysin A [Mycobacterium sp. JLS] gi|108770336|gb|ABG09058.1| hemolysin A [Mycobacterium sp. MCS] gi|119695116|gb|ABL92189.1| hemolysin A [Mycobacterium sp. KMS] gi|126235345|gb|ABN98745.1| hemolysin A [Mycobacterium sp. JLS] Length=269 Score = 394 bits (1011), Expect = 1e-107, Method: Compositional matrix adjust. Identities = 204/268 (77%), Positives = 225/268 (84%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 + RRARVDAELVRRGLARSRQQAAELIGAG+V +DG+PA KPATAV+ T + V T ER Sbjct 1 MTRRARVDAELVRRGLARSRQQAAELIGAGRVTVDGMPAAKPATAVAVTAHIAVDTADER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +WVSRGAHKL+GAL+AF I VA RR LDAGASTGGFTEVLLDRGA VVA DVGYGQLAW Sbjct 61 SWVSRGAHKLIGALDAFDIDVADRRGLDAGASTGGFTEVLLDRGAREVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR+D RVVV+ERTN R LTPE IGG VDLVVADLSFISLATVLPAL CAS DADIVP+ Sbjct 121 SLRSDERVVVVERTNVRELTPEMIGGPVDLVVADLSFISLATVLPALTACASPDADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGK +VG GGVV +P+LRA SVL+VA +A LGW +VG ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGKDRVGAGGVVSEPELRAESVLSVAAKAAGLGWETVGATASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWLR +TDR L LE AV RA++EGP Sbjct 241 LWLRARTDRGLRGDDLEQAVRRAVTEGP 268 >gi|120404265|ref|YP_954094.1| hemolysin A [Mycobacterium vanbaalenii PYR-1] gi|119957083|gb|ABM14088.1| hemolysin A [Mycobacterium vanbaalenii PYR-1] Length=269 Score = 392 bits (1007), Expect = 3e-107, Method: Compositional matrix adjust. Identities = 203/268 (76%), Positives = 223/268 (84%), Gaps = 0/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAG+VRIDG+PA KPATAVS T LTV Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGRVRIDGMPAAKPATAVSLTANLTVEGGDAD 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +WVSRGAHKL+GAL+AF ++V RRCLDAGASTGGFTEVLLDR A VVA DVGYGQLAW Sbjct 61 SWVSRGAHKLIGALDAFGLSVRARRCLDAGASTGGFTEVLLDREAREVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR DPRV V++RTN R LTPEAIGG VDLVVADLSFISLATVLPAL CAS DADIVP+ Sbjct 121 SLRTDPRVTVMDRTNVRELTPEAIGGPVDLVVADLSFISLATVLPALTACASPDADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGK +VGPGGVV DP LRA +VL+VARRA EL WH+V V ASPLPGP+GNVEYF Sbjct 181 VKPQFEVGKDRVGPGGVVSDPLLRAEAVLSVARRAAELNWHAVAVTASPLPGPAGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 + LR+ L A LE AV RA+ EGP Sbjct 241 IHLRSDGAHRLQADALEAAVRRAVDEGP 268 >gi|333990490|ref|YP_004523104.1| cytotoxin/hemolysin TlyA [Mycobacterium sp. JDM601] gi|333486458|gb|AEF35850.1| cytotoxin/hemolysin TlyA [Mycobacterium sp. JDM601] Length=268 Score = 385 bits (989), Expect = 3e-105, Method: Compositional matrix adjust. Identities = 201/268 (75%), Positives = 224/268 (84%), Gaps = 1/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RRARVDAELVRRGLARSRQQAAELIGAGKV IDG+PAVKPATAV+ + AL V D ER Sbjct 1 MSRRARVDAELVRRGLARSRQQAAELIGAGKVTIDGIPAVKPATAVTLSAALAVAGDGER 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 WVSRGAHKL+GAL+ F I VA R+CLDAGASTGGFTEVLLDRGAA VVA DVGYGQLAW Sbjct 61 GWVSRGAHKLIGALDTFGIDVADRQCLDAGASTGGFTEVLLDRGAARVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR DPRVVV+ERTN RGLTP+ IGG +L+VADLSFISLATVLPAL GCAS DAD+VP+ Sbjct 121 SLRTDPRVVVVERTNVRGLTPQIIGGLAELIVADLSFISLATVLPALAGCASPDADMVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVG+ QVG GGVV DP+LRA +VL+VA RA ELGW +V V ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGRAQVGAGGVVSDPRLRADAVLSVAHRAAELGWGTVAVTASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR S L+ AV A+++GP Sbjct 241 LHLRAAA-APRSGDALDAAVQDAVAKGP 267 >gi|145224093|ref|YP_001134771.1| hemolysin A [Mycobacterium gilvum PYR-GCK] gi|315444430|ref|YP_004077309.1| hemolysin A [Mycobacterium sp. Spyr1] gi|145216579|gb|ABP45983.1| hemolysin A [Mycobacterium gilvum PYR-GCK] gi|315262733|gb|ADT99474.1| hemolysin A [Mycobacterium sp. Spyr1] Length=268 Score = 382 bits (981), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 199/268 (75%), Positives = 218/268 (82%), Gaps = 1/268 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 + RRARVDAELVRRGLARSRQQAAELI AGKVR+DG+PA KPATAVS T L+V E Sbjct 1 MTRRARVDAELVRRGLARSRQQAAELISAGKVRVDGMPAAKPATAVSVTANLSVEAGDED 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +WVSRGAHKL+GAL+ F + VAGRRCLDAGASTGGFTEVLL R VVA DVGYGQLAW Sbjct 61 SWVSRGAHKLIGALDVFGLTVAGRRCLDAGASTGGFTEVLLSRDVREVVAVDVGYGQLAW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 S+R DPRV V+ERTN R LT EAIGG VDLVVADLSFISLATVLPAL CAS ADIVP+ Sbjct 121 SVRTDPRVTVMERTNVRDLTAEAIGGPVDLVVADLSFISLATVLPALAACASPGADIVPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGK +VG GGVV DPQLR +VL+VARRA L WH+V V ASPLPGP+GNVEYF Sbjct 181 VKPQFEVGKDRVGAGGVVSDPQLRVDAVLSVARRAASLNWHAVAVTASPLPGPAGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L LR + D A+S LE AV RA+ EGP Sbjct 241 LHLRARAD-AMSQDALEGAVRRAVDEGP 267 >gi|169629445|ref|YP_001703094.1| cytotoxin/hemolysin TlyA [Mycobacterium abscessus ATCC 19977] gi|169241412|emb|CAM62440.1| Cytotoxin/haemolysin homologue TlyA [Mycobacterium abscessus] Length=268 Score = 344 bits (883), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 187/271 (70%), Positives = 212/271 (79%), Gaps = 7/271 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +AR ARVDAELVRRGLARSRQQAAELI AG+VRIDG+PAVK ATAV T +L V ++ Sbjct 1 MARHARVDAELVRRGLARSRQQAAELIEAGRVRIDGIPAVKAATAVPATASLVVQGEAGD 60 Query 61 AWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQ 117 WVSRGAHKL+GALE F ++V G+RCLDAGASTGGFTEVLL GA VVAADVGYGQ Sbjct 61 RWVSRGAHKLLGALEVFGPQGLSVEGKRCLDAGASTGGFTEVLLRSGAREVVAADVGYGQ 120 Query 118 LAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADI 177 LAWSL++D RV VL+RTN R LTP IGG L+V+DLSFISLA VL AL+ CA DADI Sbjct 121 LAWSLQSDDRVTVLDRTNVRTLTPALIGGTAQLIVSDLSFISLALVLDALIACAGPDADI 180 Query 178 VPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNV 237 +P+VKPQFEVGK VG GGVV DPQLRA +V++VARRA+ GW + GV ASPLPGPSGNV Sbjct 181 LPMVKPQFEVGKELVGAGGVVRDPQLRADAVVSVARRARSQGWFTAGVTASPLPGPSGNV 240 Query 238 EYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 EYFLWLR R S +E AV A+S GP Sbjct 241 EYFLWLR----RTDSDVDVEAAVAEAVSRGP 267 >gi|333919193|ref|YP_004492774.1| putative hemolysin [Amycolicicoccus subflavus DQS3-9A1] gi|333481414|gb|AEF39974.1| Putative hemolysin [Amycolicicoccus subflavus DQS3-9A1] Length=273 Score = 319 bits (818), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 171/272 (63%), Positives = 198/272 (73%), Gaps = 4/272 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 +ARRARVDAELVRRG+ARSR A ELI AG+V+ G VKPATA+ T L V+ + S+ Sbjct 1 MARRARVDAELVRRGMARSRDHAVELIAAGRVQSAGSTIVKPATAIDRATPLHVIENPSD 60 Query 60 RAWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 W SRGAHKL+GALE F + V GRRCLDAGASTGGFT+VLL RGA VVAADVGYG Sbjct 61 EEWASRGAHKLLGALERFGPGGLEVTGRRCLDAGASTGGFTDVLLKRGAREVVAADVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L+NDPRV + +RTN R LTPE IGG VDLVVADLSFISL VLPAL C + AD Sbjct 121 QLIWRLQNDPRVEIFDRTNVRSLTPEQIGGPVDLVVADLSFISLRLVLPALANCVTPGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 ++P+VKPQFEVGK ++G GGVV DP+LRA V VA A LG ++ ASPLPGPSGN Sbjct 181 LMPMVKPQFEVGKERLGSGGVVRDPELRASVVREVADYADGLGLRAIDAVASPLPGPSGN 240 Query 237 VEYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 VEYFLWLR+ L + + RA+ EGP Sbjct 241 VEYFLWLRSGEAGPAPTASLSEMISRAVEEGP 272 >gi|226306754|ref|YP_002766714.1| hemolysin [Rhodococcus erythropolis PR4] gi|226185871|dbj|BAH33975.1| putative hemolysin [Rhodococcus erythropolis PR4] Length=285 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 174/284 (62%), Positives = 205/284 (73%), Gaps = 16/284 (5%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVV-TDSE 59 +ARRARVDAELVRRGLARSR A ELI AG+V I G A KPATA+ T L VV + E Sbjct 1 MARRARVDAELVRRGLARSRDHAQELISAGRVLISGAVATKPATAIEAGTPLRVVEVEQE 60 Query 60 RAWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +W SRGAHKL+GAL+AF + V GRRCLDAGASTGGFT+VLL RGA VVA DVGYG Sbjct 61 VSWASRGAHKLIGALDAFGTEGLTVEGRRCLDAGASTGGFTDVLLTRGAKEVVAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L++D RV V++RTN R + E IGG VDLVVADLSFISL VL A V C + AD Sbjct 121 QLVWRLQSDDRVHVIDRTNVRAIDAETIGGTVDLVVADLSFISLKLVLGAFVACTADGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 +VP+VKPQFEVGK +VG GGVV DP+LR +VL V+ A ++G ++GV ASPLPGPSGN Sbjct 181 LVPMVKPQFEVGKDRVGAGGVVRDPELRISAVLDVSEAAAKVGLRTLGVVASPLPGPSGN 240 Query 237 VEYFLWLR---------TQTDRALSAKGL---EDAVHRAISEGP 268 VEYFLWLR T TD + +G+ ED + +A+ EGP Sbjct 241 VEYFLWLRKTGTSGDEETDTDAETNTEGIPTVEDMIRKAVEEGP 284 >gi|111017953|ref|YP_700925.1| hemolysin [Rhodococcus jostii RHA1] gi|110817483|gb|ABG92767.1| possible hemolysin [Rhodococcus jostii RHA1] Length=324 Score = 317 bits (811), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 172/275 (63%), Positives = 201/275 (74%), Gaps = 7/275 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVV-TDSE 59 VARRARVDAELVRRGLARSR+ A ELI +G+V I G A KPATA+ T L VV D+E Sbjct 49 VARRARVDAELVRRGLARSREHAQELIASGRVLISGAAATKPATAIEAGTPLRVVEVDNE 108 Query 60 RAWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +W SRGAHKL+GALEAF + V +RCLDAGASTGGFT+VLL GA VVA DVGYG Sbjct 109 VSWASRGAHKLLGALEAFGPRGLEVEAKRCLDAGASTGGFTDVLLHHGAREVVAVDVGYG 168 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L++D RV V++RTN R + E IGG VDLVVADLSFISL VLPA VGC + AD Sbjct 169 QLVWRLQSDDRVHVIDRTNVRSIDAEQIGGPVDLVVADLSFISLKLVLPAFVGCVADGAD 228 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 ++P+VKPQFEVGK VG GGVV DP+LR +VL VA+ A LG +VG ASPLPGPSGN Sbjct 229 LIPMVKPQFEVGKDHVGSGGVVRDPELRVAAVLDVAKTAASLGLRTVGAVASPLPGPSGN 288 Query 237 VEYFLWLR---TQTDRALSAKGLEDAVHRAISEGP 268 VEYFLWLR T + + +E+ + A+ EGP Sbjct 289 VEYFLWLRADVTPGTDDVPVESIEELIRTAVQEGP 323 >gi|226360083|ref|YP_002777861.1| hemolysin [Rhodococcus opacus B4] gi|226238568|dbj|BAH48916.1| putative hemolysin [Rhodococcus opacus B4] Length=276 Score = 316 bits (810), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 172/275 (63%), Positives = 202/275 (74%), Gaps = 7/275 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVV-TDSE 59 +ARRARVDAELVRRGLARSR+ A ELI +G+V I G A KPATA+ T L VV D+E Sbjct 1 MARRARVDAELVRRGLARSREHAQELIASGRVLISGAAATKPATAIEAGTPLRVVEVDNE 60 Query 60 RAWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +W SRGAHKL+GALEAF +AV G+RCLDAGASTGGFT+VLL GA VVA DVGYG Sbjct 61 VSWASRGAHKLLGALEAFGPRGLAVDGKRCLDAGASTGGFTDVLLHHGAREVVAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L++D RV V++RTN R + E IGG V+LVVADLSFISL VLPA V C + AD Sbjct 121 QLVWRLQSDDRVHVVDRTNVRSIDAEQIGGPVELVVADLSFISLKLVLPAFVACVTDGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 ++P+VKPQFEVGK VG GGVV DP+LR SVL VA+ A LG +VG ASPLPGPSGN Sbjct 181 LIPMVKPQFEVGKDHVGSGGVVRDPELRVASVLDVAKTAASLGLRTVGAVASPLPGPSGN 240 Query 237 VEYFLWLR---TQTDRALSAKGLEDAVHRAISEGP 268 VEYFLWLR T + + +E+ + A+ EGP Sbjct 241 VEYFLWLRADVTPGTDDVPVESVEELIRTAVQEGP 275 >gi|229494834|ref|ZP_04388588.1| hemolysin A [Rhodococcus erythropolis SK121] gi|229318272|gb|EEN84139.1| hemolysin A [Rhodococcus erythropolis SK121] Length=279 Score = 313 bits (803), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 172/278 (62%), Positives = 203/278 (74%), Gaps = 10/278 (3%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVV-TDSE 59 +ARRARVDAELVRRGLARSR A ELI AG+V I G A KPATA+ T L VV + E Sbjct 1 MARRARVDAELVRRGLARSRDHAQELISAGRVLISGAVATKPATAIEAGTPLRVVEVEQE 60 Query 60 RAWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +W SRGAHKL+GAL+AF + V GRRCLDAGASTGGFT+VLL RGA VVA DVGYG Sbjct 61 VSWASRGAHKLIGALDAFGAEGLTVEGRRCLDAGASTGGFTDVLLTRGAKEVVAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L++D RV V++RTN R + E IGG VDLVVADLSFISL VL A V C + AD Sbjct 121 QLVWRLQSDDRVHVIDRTNVRAIDAETIGGTVDLVVADLSFISLKLVLGAFVACTADGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 +VP+VKPQFEVGK +VG GGVV DP+LR +VL V+ A ++G ++GV ASPLPGPSGN Sbjct 181 LVPMVKPQFEVGKDRVGAGGVVRDPELRISAVLDVSEAAAKVGLRTLGVVASPLPGPSGN 240 Query 237 VEYFLWLR---TQTDRALSAKGL---EDAVHRAISEGP 268 VEYFLWLR + D +G+ ED + +A+ EGP Sbjct 241 VEYFLWLRKTGSPGDHEPDTEGIPSVEDMIRKAVEEGP 278 >gi|284991439|ref|YP_003409993.1| hemolysin A [Geodermatophilus obscurus DSM 43160] gi|284064684|gb|ADB75622.1| hemolysin A [Geodermatophilus obscurus DSM 43160] Length=265 Score = 310 bits (795), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 173/269 (65%), Positives = 199/269 (74%), Gaps = 6/269 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 + RR+R+DAELVRRGLARSR+ A LI G+V + G A KPAT V T + V TD E Sbjct 1 MVRRSRLDAELVRRGLARSREHAVALIADGRVAVSGRAATKPATGVDANTPVVVRTDPDE 60 Query 60 RAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 +WVSRGAHKL+GALEAF + V GRR LDAGASTGGFTEVLL RGA VVA DVGYG+LA Sbjct 61 PSWVSRGAHKLLGALEAFPVPVEGRRALDAGASTGGFTEVLLRRGAREVVAVDVGYGELA 120 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVP 179 WSLR D RV VLERTNAR LT E + G VDLVVADLSFISL VLPAL CA+ AD++P Sbjct 121 WSLRTDERVRVLERTNARTLTAEQVDGPVDLVVADLSFISLRLVLPALASCATDAADLLP 180 Query 180 LVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEY 239 +VKPQFEVG+ ++G GGVV DP R +VL VAR A ++GW + GV ASPLPGP+GNVE+ Sbjct 181 MVKPQFEVGRERLGAGGVVRDPAHRQDAVLQVARAAAQIGWGTAGVVASPLPGPAGNVEF 240 Query 240 FLWLRTQTDRALSAKGLEDAVHRAISEGP 268 FLWLR R ED V RA+ EGP Sbjct 241 FLWLR----RDAGPPCGED-VRRAVEEGP 264 >gi|300787880|ref|YP_003768171.1| hemolysin-like protein [Amycolatopsis mediterranei U32] gi|299797394|gb|ADJ47769.1| putative hemolysin-like protein [Amycolatopsis mediterranei U32] gi|340529452|gb|AEK44657.1| hemolysin-like protein [Amycolatopsis mediterranei S699] Length=275 Score = 310 bits (793), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 165/272 (61%), Positives = 196/272 (73%), Gaps = 6/272 (2%) Query 3 RRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAW 62 +RAR+DAELVRRGLARSR+QA+ LI GKV + G+ A KPAT V + V + + W Sbjct 3 KRARLDAELVRRGLARSREQASALITDGKVTVRGMVATKPATGVESGAPIVVKDEDDPGW 62 Query 63 VSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWS 121 SRGAHKL+GALEAF + V G+RCLDAGASTGGFT+VLL GAA V+AADVG G L W Sbjct 63 ASRGAHKLLGALEAFTELTVEGKRCLDAGASTGGFTDVLLRNGAATVIAADVGRGLLDWR 122 Query 122 LRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLV 181 +R D RVVV++RTN R LTPE +GG+VDL+V DLSFISL VLPAL CA AD+VP+V Sbjct 123 IRTDDRVVVMDRTNVRNLTPEDLGGQVDLIVGDLSFISLKLVLPALAACAREGADLVPMV 182 Query 182 KPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFL 241 KPQFEVGK ++G GGVV DP+LRA SVL V A +LG GV ASPLPGPSGNVEYF+ Sbjct 183 KPQFEVGKDRLGSGGVVRDPELRAESVLTVIDEAAKLGLALCGVTASPLPGPSGNVEYFV 242 Query 242 WLRTQ-----TDRALSAKGLEDAVHRAISEGP 268 WL+ + T A+ E V A+ EGP Sbjct 243 WLKKEQVAESTVDAVDRSEAERLVRTAVEEGP 274 >gi|302528025|ref|ZP_07280367.1| ribosomal RNA large subunit methyltransferase J [Streptomyces sp. AA4] gi|302436920|gb|EFL08736.1| ribosomal RNA large subunit methyltransferase J [Streptomyces sp. AA4] Length=275 Score = 308 bits (788), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 164/271 (61%), Positives = 194/271 (72%), Gaps = 3/271 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 VA+RAR+DAELVRRGLARSR+QA+ LI GKV + G+ A KPAT V + + V + + Sbjct 4 VAKRARLDAELVRRGLARSREQASALITGGKVTVRGMVATKPATGVENDAPIVVKDEDDP 63 Query 61 AWVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQ 117 W SRGAHKL+GAL+ F + V GRRCLDAGASTGGFT+VLL GA V+AADVG G Sbjct 64 GWASRGAHKLLGALDRFGPEGLTVEGRRCLDAGASTGGFTDVLLRNGAEKVIAADVGRGL 123 Query 118 LAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADI 177 L W L+ D RVVVL+RTN R LTP+ +GG+VDLVV DLSFISL VLPAL CA AD+ Sbjct 124 LDWKLQTDDRVVVLDRTNVRNLTPDVLGGQVDLVVGDLSFISLKLVLPALAACARDGADL 183 Query 178 VPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNV 237 VP+VKPQFEVGK ++G GGVV DP+LR SVL V A +LG GV ASPLPGPSGNV Sbjct 184 VPMVKPQFEVGKDRLGSGGVVRDPELRVESVLGVLAEAAKLGLSLRGVVASPLPGPSGNV 243 Query 238 EYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 EYF+WLR ++ E V A+ EGP Sbjct 244 EYFVWLRKTEPEDAGSEEAEPLVRAAVQEGP 274 >gi|343928398|ref|ZP_08767846.1| hemolysin [Gordonia alkanivorans NBRC 16433] gi|343761583|dbj|GAA14772.1| hemolysin [Gordonia alkanivorans NBRC 16433] Length=286 Score = 306 bits (785), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 171/285 (60%), Positives = 202/285 (71%), Gaps = 17/285 (5%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +A RAR+DAELVRRGLARSR+QA EL+ AG V+++G A K AT V+ T + VV + Sbjct 1 MATRARLDAELVRRGLARSREQARELVDAGVVKVNGTVAAKAATGVTRDTPIVVVEAPKD 60 Query 61 AWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQ 117 W SRGAHKL+GALEAF +++AGRRCLDAGASTGGFT+VLL R VVA DVGYGQ Sbjct 61 DWASRGAHKLLGALEAFEPQGLSLAGRRCLDAGASTGGFTDVLLRRDVREVVAVDVGYGQ 120 Query 118 LAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADI 177 L W L+ND RV V +RTN R L PEAIGG VD+VVADLSFISL VLPA CA AD+ Sbjct 121 LIWRLQNDDRVHVHDRTNVRHLEPEAIGGPVDVVVADLSFISLGLVLPAFARCAVPGADL 180 Query 178 VPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNV 237 +P+VKPQFEVGK +VG GGVV DP LRA +VLAVA A LG + GV ASPLPGPSGNV Sbjct 181 LPMVKPQFEVGKDRVGSGGVVRDPALRAEAVLAVATEAAALGLVTRGVVASPLPGPSGNV 240 Query 238 EYFLWLRTQ--------------TDRALSAKGLEDAVHRAISEGP 268 E+FLWLR + D + S+ L + RA++EGP Sbjct 241 EFFLWLRNEPGGRTGEESGESDRVDPSASSDELRSMIERAVAEGP 285 >gi|72162433|ref|YP_290090.1| hemolysin A [Thermobifida fusca YX] gi|71916165|gb|AAZ56067.1| hemolysin A [Thermobifida fusca YX] Length=266 Score = 306 bits (783), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 174/270 (65%), Positives = 200/270 (75%), Gaps = 7/270 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTV-VTDSE 59 +ARR+R+DAELVRRG ARSR AAELI AG+VR+ G A K AT V A+ V D E Sbjct 1 MARRSRLDAELVRRGHARSRAHAAELIAAGRVRVAGTLATKAATQVGVDQAIVVEQADDE 60 Query 60 RAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 +VSRGA+KL+GAL+AFA+ V GRRCLDAGASTGGFT+VLL RGAAHVVA DVGYGQLA Sbjct 61 PVYVSRGAYKLIGALDAFAVDVTGRRCLDAGASTGGFTDVLLRRGAAHVVAVDVGYGQLA 120 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGG-RVDLVVADLSFISLATVLPALVGCASRDADIV 178 WSLR+DPRV VLER N R LTP+ +G R DLVVADLSFISL VL L+ CA+ DAD V Sbjct 121 WSLRSDPRVTVLERQNVRELTPDQVGEPRPDLVVADLSFISLRLVLAPLLACAASDADFV 180 Query 179 PLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVE 238 LVKPQFEVG+ +VG GVV DP+ RA +V VA A LG GV ASPLPGPSGNVE Sbjct 181 LLVKPQFEVGRERVGAKGVVRDPEARASAVRDVAAHAWTLGLGVCGVTASPLPGPSGNVE 240 Query 239 YFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 YFLWLR+ +A E + RA++EGP Sbjct 241 YFLWLRSG-----AAPLDERQLERAVAEGP 265 >gi|262202727|ref|YP_003273935.1| hemolysin A [Gordonia bronchialis DSM 43247] gi|262086074|gb|ACY22042.1| hemolysin A [Gordonia bronchialis DSM 43247] Length=275 Score = 305 bits (782), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 169/275 (62%), Positives = 200/275 (73%), Gaps = 8/275 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +A RAR+DAELVRRGLARSR+ A L+ +G V+++G+ A KPAT V+ T + VV + Sbjct 1 MATRARLDAELVRRGLARSREHARHLVDSGVVKVNGVVATKPATNVTRDTPVLVVEEQGE 60 Query 61 AWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQ 117 W SRGAHKL+GAL+AF + VAGRRCLDAGASTGGFT+VLL RGAA VVA DVGYGQ Sbjct 61 DWASRGAHKLIGALDAFEPAGLEVAGRRCLDAGASTGGFTDVLLRRGAARVVAVDVGYGQ 120 Query 118 LAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADI 177 L W L+ND RV + +RTN R L P+ IGG VD+VVADLSFISL VLPAL C+ AD+ Sbjct 121 LIWRLQNDDRVEIHDRTNVRHLEPDEIGGPVDVVVADLSFISLGLVLPALARCSRPGADL 180 Query 178 VPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNV 237 VP+VKPQFEVGK +VG GGVV DP LRA +V VAR+A E+ GV ASPLPGPSGNV Sbjct 181 VPMVKPQFEVGKDRVGSGGVVRDPALRAEAVHNVARQAAEVDLMPCGVVASPLPGPSGNV 240 Query 238 EYFLWLRTQTDRALSAKG----LEDAVHRAISEGP 268 EYFLWL Q A S G L + RA+ +GP Sbjct 241 EYFLWLHHQPGGA-SGGGDRVDLRSLIERAVDDGP 274 >gi|296140085|ref|YP_003647328.1| hemolysin A [Tsukamurella paurometabola DSM 20162] gi|296028219|gb|ADG78989.1| hemolysin A [Tsukamurella paurometabola DSM 20162] Length=271 Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 161/271 (60%), Positives = 198/271 (74%), Gaps = 4/271 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAV--SDTTALTVVTDS 58 +ARR R+DAELVRRG+ARSR+QA ELI +G+V ++ A K A + +D +T V Sbjct 1 MARRVRLDAELVRRGMARSREQARELIESGRVTVNKQVARKAANQIDPADPVHVTAVA-G 59 Query 59 ERAWVSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQ 117 E W SRGAHKL+GAL+AF + VAGRRCLDAGASTGGFT+VLL RGA V A DVGYG+ Sbjct 60 EIDWASRGAHKLIGALDAFPDVTVAGRRCLDAGASTGGFTDVLLHRGAERVYAVDVGYGE 119 Query 118 LAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADI 177 L W LR+D RV V++RTN R L P A+ G VDLVV DLSFISL+ VLPA+ C + AD+ Sbjct 120 LVWRLRDDARVTVMDRTNVRTLEPGALDGPVDLVVGDLSFISLSLVLPAMAACTAVGADL 179 Query 178 VPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNV 237 +P++KPQFEVGKG VG GGVV DPQLRA +VLAVAR A + G + GV SPLPGPSGNV Sbjct 180 LPMIKPQFEVGKGNVGSGGVVRDPQLRASAVLAVARTAADHGLRTRGVTYSPLPGPSGNV 239 Query 238 EYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 EYFLWLR + +++ + A++EGP Sbjct 240 EYFLWLRREDGPVTLPADVDEMIATAVAEGP 270 >gi|54023964|ref|YP_118206.1| putative cytotoxin/hemolysin [Nocardia farcinica IFM 10152] gi|54015472|dbj|BAD56842.1| putative cytotoxin/hemolysin [Nocardia farcinica IFM 10152] Length=273 Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 174/272 (64%), Positives = 193/272 (71%), Gaps = 4/272 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 +ARRARVDAELVRRGLARSR+ A ELIGAG+V I G A KPATAV T L V E Sbjct 1 MARRARVDAELVRRGLARSREHAVELIGAGRVLIAGTVASKPATAVEPGTPLVVREQPDE 60 Query 60 RAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 W SRGAHKL+GALE F + VAG+RCLDAGASTGGFT+VLL R A VVA DVGYG Sbjct 61 VQWASRGAHKLLGALERFERAGLRVAGKRCLDAGASTGGFTDVLLSREAREVVAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W LR D RV V +RTN R LTPE I G V+LVV DLSFISL VLPAL C + AD Sbjct 121 QLVWRLRTDERVRVFDRTNVRTLTPELIEGAVELVVGDLSFISLGLVLPALASCCAEGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 ++P+VKPQFEVGK +VG GGVV DP LRA +V VA A E G +VG ASPLPGPSGN Sbjct 181 LLPMVKPQFEVGKERVGSGGVVRDPALRAEAVCGVAAAAAEHGLRTVGAVASPLPGPSGN 240 Query 237 VEYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 VEYFLWLR A + + V RA+ EGP Sbjct 241 VEYFLWLRKDGPFEYDAAQVRELVARAVEEGP 272 >gi|325674266|ref|ZP_08153955.1| cytotoxin/hemolysin [Rhodococcus equi ATCC 33707] gi|325554946|gb|EGD24619.1| cytotoxin/hemolysin [Rhodococcus equi ATCC 33707] Length=282 Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 176/281 (63%), Positives = 200/281 (72%), Gaps = 13/281 (4%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRARVDAELVRRGLARSR+QA ELI AG+V I G A KPATA+ T L V +E Sbjct 1 MARRARVDAELVRRGLARSREQAVELIAAGRVLISGTVATKPATAIEAGTPLLVTEVAEE 60 Query 61 -AWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +W SRGAHKL+GALEAF +AV GRRCLDAGASTGGFT+VLL GA VVA DVGYG Sbjct 61 VSWASRGAHKLIGALEAFMPHGLAVEGRRCLDAGASTGGFTDVLLHNGAREVVAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QL W L+ D RV V +RTN R + E IGG VDLVV+DLSFISL VLPALV C + AD Sbjct 121 QLVWKLQTDDRVHVHDRTNVRSIDAETIGGPVDLVVSDLSFISLKLVLPALVACVNEGAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 +VP+VKPQFEVGK +VG GGVV DP+LR +VL VA A LG ++G ASPLPGPSGN Sbjct 181 LVPMVKPQFEVGKDRVGAGGVVRDPELRVGAVLEVAEAAAALGLQTLGAVASPLPGPSGN 240 Query 237 VEYFLWLRT---QTDRAL------SAKGLEDAVHRAISEGP 268 VEYFLWLR D L + +E V RA+ EGP Sbjct 241 VEYFLWLRKGDPTPDADLPEGEGGEIRDVEALVRRAVEEGP 281 >gi|296269986|ref|YP_003652618.1| hemolysin A [Thermobispora bispora DSM 43833] gi|296092773|gb|ADG88725.1| hemolysin A [Thermobispora bispora DSM 43833] Length=269 Score = 298 bits (763), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 172/268 (65%), Positives = 195/268 (73%), Gaps = 5/268 (1%) Query 4 RARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERA-- 61 R R+D ELVRRGLARSR+ AA LI AG+V + G A KPAT V DT A VV ++ Sbjct 3 RVRLDRELVRRGLARSREHAARLIEAGRVYVRGSVAEKPATQV-DTGAPIVVAEAAEGPE 61 Query 62 WVSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 +VSRGA+KL+GALEAF + VAGRRCLDAGASTGGFT+VLL GAAHV+A DVGYGQLAW Sbjct 62 YVSRGAYKLLGALEAFTGLQVAGRRCLDAGASTGGFTDVLLRHGAAHVIAVDVGYGQLAW 121 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 SLR D RV VLER N R LTPE +G L+V DLSFISL VLPALV CA+ AD V L Sbjct 122 SLRTDERVTVLERVNVRDLTPEMVGEPPTLIVGDLSFISLRLVLPALVRCAAGTADFVLL 181 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGKG+VGPGGVV DP LRA +V VA AQ LG GV ASPLPGP+GNVEY Sbjct 182 VKPQFEVGKGRVGPGGVVRDPALRAEAVRDVATAAQGLGLTVKGVTASPLPGPAGNVEYL 241 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 LWL + L+ A+ RA++EGP Sbjct 242 LWLGKGPGHE-AVPDLDAAIERAVAEGP 268 >gi|284033301|ref|YP_003383232.1| hemolysin A [Kribbella flavida DSM 17836] gi|283812594|gb|ADB34433.1| hemolysin A [Kribbella flavida DSM 17836] Length=272 Score = 296 bits (759), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 166/271 (62%), Positives = 199/271 (74%), Gaps = 11/271 (4%) Query 3 RRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD--SER 60 +R+R+DAELVRRGLARSR+ A+EL+ AGKV++ G A KPAT V + V T + Sbjct 7 KRSRLDAELVRRGLARSREHASELVAAGKVKVSGAVATKPATGVGADAPILVDTSETDDP 66 Query 61 AWVSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 + SRGAHKLVGALEAF+ + V GRRCLDAGASTGGFT+VLL GAA V+A DVGYGQL Sbjct 67 NYASRGAHKLVGALEAFSGVEVKGRRCLDAGASTGGFTDVLLRNGAASVLAVDVGYGQLV 126 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRDADIV 178 W+L+ D RV V++RTN R LT +AIGG VDLVV+DLSFISL VLPAL+G D D+V Sbjct 127 WALQTDDRVTVMDRTNVRTLTLDAIGGDPVDLVVSDLSFISLTLVLPALLGVVKPDGDLV 186 Query 179 PLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVE 238 +VKPQFEVGK ++G GGVV DP LRA +V VA +A ELGW GV ASPLPGPSGNVE Sbjct 187 LMVKPQFEVGKERLGKGGVVRDPDLRADAVRGVAAKAAELGWGVQGVAASPLPGPSGNVE 246 Query 239 YFLWLRTQTDRALSAKGLEDAVHR-AISEGP 268 YFLW+R SA L++ + R A+ GP Sbjct 247 YFLWIRR------SAPPLDETMLRDAVESGP 271 >gi|256379446|ref|YP_003103106.1| hemolysin A [Actinosynnema mirum DSM 43827] gi|255923749|gb|ACU39260.1| hemolysin A [Actinosynnema mirum DSM 43827] Length=268 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 159/245 (65%), Positives = 183/245 (75%), Gaps = 1/245 (0%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARRAR+DAELVRRG+ARSR+ A++L+ GKV + G A KPATAV TAL V + Sbjct 1 MARRARLDAELVRRGMARSREHASQLVAEGKVTVRGSVATKPATAVELDTALVVRDTDDP 60 Query 61 AWVSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 W SRGAHKLVGALEAF + V G+RCLDAGASTGGFT+VLL GA VVAADVG G L Sbjct 61 NWASRGAHKLVGALEAFGGVDVTGKRCLDAGASTGGFTDVLLRAGARQVVAADVGRGLLD 120 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVP 179 W L+ D RVVV +RTN R LTPE IGG V+LVVADLSFISL VLPAL C + D++P Sbjct 121 WKLQTDERVVVKDRTNVRSLTPEVIGGPVELVVADLSFISLRLVLPALAACLDEEGDLLP 180 Query 180 LVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEY 239 +VKPQFEVGK ++G GGVV DP+LRA +VL V A LG GV ASPLPGPSGNVE+ Sbjct 181 MVKPQFEVGKERLGSGGVVRDPELRAAAVLEVVEAAAGLGLRLHGVVASPLPGPSGNVEF 240 Query 240 FLWLR 244 F WLR Sbjct 241 FAWLR 245 >gi|271967338|ref|YP_003341534.1| hemolysin A [Streptosporangium roseum DSM 43021] gi|270510513|gb|ACZ88791.1| hemolysin A [Streptosporangium roseum DSM 43021] Length=272 Score = 293 bits (751), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 166/272 (62%), Positives = 196/272 (73%), Gaps = 5/272 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 ++RR R+D+ELVRR LARSR+QAA+LI AG+V + G A KPAT V +A+ V +E Sbjct 1 MSRRTRLDSELVRRKLARSREQAAQLIEAGRVSVGGQLAAKPATQVDTASAIVVAEAAEG 60 Query 61 A-WVSRGAHKLVGALEAFA---IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +VSRGAHKL+GALEAF + VAGRRCLDAGASTGGFT+VLL AAHV+A DVGYG Sbjct 61 PDYVSRGAHKLLGALEAFGPRGLTVAGRRCLDAGASTGGFTDVLLRNDAAHVLAVDVGYG 120 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDAD 176 QLAWSLR D RV V+ER N R LTP+ +G L+V DLSFISL VLPAL CA+ AD Sbjct 121 QLAWSLRTDERVTVMERVNVRDLTPDMVGEPPTLIVGDLSFISLRLVLPALTLCAAERAD 180 Query 177 IVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGN 236 LVKPQFEVGK +VG GGVV DP LRA++V VA AQ LG GV ASPLPGPSGN Sbjct 181 FAMLVKPQFEVGKERVGAGGVVRDPVLRAQAVRDVAGAAQALGLTVRGVTASPLPGPSGN 240 Query 237 VEYFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 VEY +WL + + AL + V RA++EGP Sbjct 241 VEYVIWL-GKGEGALPVADIGAEVERAVAEGP 271 >gi|291003073|ref|ZP_06561046.1| putative cytotoxin/hemolysin [Saccharopolyspora erythraea NRRL 2338] Length=282 Score = 293 bits (750), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 157/243 (65%), Positives = 181/243 (75%), Gaps = 4/243 (1%) Query 7 VDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SERAWVSR 65 +DAELVRRGLARSR+ A+EL+ AG+V + G+ A K ATAV + V D + W SR Sbjct 1 MDAELVRRGLARSREHASELVAAGRVSVRGMVARKSATAVELDAPVLVAEDVDDPGWASR 60 Query 66 GAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSL 122 GAHKL+GALEAF V GRRCLDAGASTGGFT+VLL RGA VVA DVGYGQL W L Sbjct 61 GAHKLLGALEAFEPEGFRVDGRRCLDAGASTGGFTDVLLRRGAKEVVAVDVGYGQLVWKL 120 Query 123 RNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLVK 182 + D RV + +RTN R LTPE IGG+V+LVVADLSFISL VLPAL+ CA+ ADIVP++K Sbjct 121 QTDERVKIHDRTNVRSLTPEEIGGQVELVVADLSFISLKLVLPALIACAAEGADIVPMIK 180 Query 183 PQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFLW 242 PQFEVGK ++G GGVV DP LRA +VL V R A+ G GV ASPLPGPSGNVEYF W Sbjct 181 PQFEVGKQRLGSGGVVRDPDLRADAVLEVVRFAENSGLGLRGVVASPLPGPSGNVEYFAW 240 Query 243 LRT 245 LR Sbjct 241 LRV 243 >gi|258654197|ref|YP_003203353.1| hemolysin A [Nakamurella multipartita DSM 44233] gi|258557422|gb|ACV80364.1| hemolysin A [Nakamurella multipartita DSM 44233] Length=272 Score = 293 bits (749), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 165/270 (62%), Positives = 195/270 (73%), Gaps = 4/270 (1%) Query 3 RRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVV-TDSERA 61 RR+R+DAELVRRG ARSR +AAE I AG+V + G A KP+TAV AL V D + Sbjct 2 RRSRLDAELVRRGHARSRAEAAEFIAAGRVLVAGQVATKPSTAVDPAVALLVRDADLDPR 61 Query 62 WVSRGAHKLVGALEAFA-IAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 W SRGAHKL+GAL+AF + V GRRCLDAGASTGGFT+VLL RGA VVA DVGYG L W Sbjct 62 WASRGAHKLIGALDAFTDVVVDGRRCLDAGASTGGFTDVLLRRGAREVVAVDVGYGLLVW 121 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 +L++D RV V +RTN R LTPEAIGG VDLVVADLSFISL VLPAL+ CA DAD++P+ Sbjct 122 ALQSDERVHVHDRTNIRHLTPEAIGGPVDLVVADLSFISLTLVLPALIACAHPDADLIPM 181 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVGK ++G GGVV D LRA +V V + A LGW GV ASPLPGPSGNVE+F Sbjct 182 VKPQFEVGKERLGAGGVVRDRALRAEAVATVVQAAGLLGWGMAGVVASPLPGPSGNVEFF 241 Query 241 LWLR--TQTDRALSAKGLEDAVHRAISEGP 268 + LR T + + + + A+ EGP Sbjct 242 VHLRRDTAVEDPFADGRCAELIATAVGEGP 271 >gi|336179106|ref|YP_004584481.1| hemolysin A [Frankia symbiont of Datisca glomerata] gi|334860086|gb|AEH10560.1| hemolysin A [Frankia symbiont of Datisca glomerata] Length=335 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 164/259 (64%), Positives = 182/259 (71%), Gaps = 16/259 (6%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +ARR R+D ELVRRGL RSR+QA E I G+VR+ G PA KPAT V D T + +V + Sbjct 1 MARRTRLDRELVRRGLVRSREQAGEAIVGGRVRVAGRPATKPATVVDDMTPIVIVAGDDP 60 Query 61 AWVSRGAHKLVGALEAFA----------------IAVAGRRCLDAGASTGGFTEVLLDRG 104 +VSRGAHKL+ AL AF + VAGRRCLDAGASTGGFT++LL Sbjct 61 GYVSRGAHKLLAALSAFGGNAASQQAAGGGGVGRLWVAGRRCLDAGASTGGFTDLLLRHD 120 Query 105 AAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVL 164 AA VVA DVGYGQLAW LRNDPRV VLERTN R LT EAIGG VDLVVADLSFISL VL Sbjct 121 AAEVVAVDVGYGQLAWQLRNDPRVTVLERTNVRFLTAEAIGGPVDLVVADLSFISLRLVL 180 Query 165 PALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVG 224 PAL CA AD V LVKPQFEVG+ +GPGGVV D L AR+V VA+ A EL G Sbjct 181 PALRACARPAADFVVLVKPQFEVGRADLGPGGVVRDVALHARAVWDVAQAAAELSLGVRG 240 Query 225 VKASPLPGPSGNVEYFLWL 243 V ASPLPGP+GNVEY LWL Sbjct 241 VVASPLPGPAGNVEYLLWL 259 >gi|172040777|ref|YP_001800491.1| hypothetical protein cur_1097 [Corynebacterium urealyticum DSM 7109] gi|171852081|emb|CAQ05057.1| hypothetical protein cu1097 [Corynebacterium urealyticum DSM 7109] Length=262 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 148/261 (57%), Positives = 189/261 (73%), Gaps = 4/261 (1%) Query 12 VRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSERAWVSRGAHKLV 71 +RR +ARSR+QA ++I G+V+++G+ A KPAT V+ ++ V E W SRGAHKL+ Sbjct 1 MRRKIARSREQAQKMIKEGRVQVNGMLAQKPATGVNAEVSIRVAESEEDHWASRGAHKLL 60 Query 72 GALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAWSLRNDPRV 128 GAL AF +++ G+R LDAGASTGGFT+V LDRGA+ V+A DVGYGQL W L+NDPRV Sbjct 61 GALAAFEPQGLSLEGKRVLDAGASTGGFTDVALDRGASEVLAVDVGYGQLIWRLQNDPRV 120 Query 129 VVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPLVKPQFEVG 188 V++RTN R LTPEAIGG D++V DLSFIS+ VLPA+ C + AD++P+VKPQFEVG Sbjct 121 TVMDRTNVRTLTPEAIGGPADVMVGDLSFISIKLVLPAIAECMAEGADLLPMVKPQFEVG 180 Query 189 KGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYFLWL-RTQT 247 K ++GPGGVV P+LRA L VAR A + G + V ASPLPGPSGNVEYFLWL + Sbjct 181 KNRLGPGGVVRSPELRAEVTLDVAREALKYGLSTKAVVASPLPGPSGNVEYFLWLSKDGG 240 Query 248 DRALSAKGLEDAVHRAISEGP 268 +A + LE V A+ EGP Sbjct 241 KQAPTMDTLEAMVSTAVKEGP 261 >gi|302546497|ref|ZP_07298839.1| cytotoxin/hemolysin [Streptomyces hygroscopicus ATCC 53653] gi|302464115|gb|EFL27208.1| cytotoxin/hemolysin [Streptomyces himastatinicus ATCC 53653] Length=288 Score = 290 bits (742), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 171/290 (59%), Positives = 202/290 (70%), Gaps = 31/290 (10%) Query 3 RRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVT--DSER 60 RR R+DAELVRR LARSR+ A++LI AG+V + G A K AT V +T+A VVT DS+ Sbjct 5 RRVRLDAELVRRKLARSREHASQLIAAGRVTVGGATATKAATQV-ETSAAVVVTKDDSDP 63 Query 61 AWVSRGAHKLVGALEAFA--------------------IAVAGRRCLDAGASTGGFTEVL 100 +VSRG HKL GAL AF+ + VAGRR LDAGASTGGFT+VL Sbjct 64 DYVSRGGHKLAGALYAFSEEYREGAGRTTDPTPVSGSGLTVAGRRALDAGASTGGFTDVL 123 Query 101 LDRGAAHVVAADVGYGQLAWSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFIS 159 L GA HVVAADVGYGQLAWSL++D RV VL+RTN R LTPE +GG VDLVV DLSFI Sbjct 124 LRAGATHVVAADVGYGQLAWSLQSDERVTVLDRTNVRELTPEQMGGEPVDLVVGDLSFIP 183 Query 160 LATVLPALVGCASRDADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELG 219 L VLPALV C + DAD+V +VKPQFEVGK ++G GGVV +LRA +V VA +A +LG Sbjct 184 LGLVLPALVRCTAPDADLVLMVKPQFEVGKERLGSGGVVRSAELRAEAVRTVAHQAADLG 243 Query 220 WHSVGVKASPLPGPSGNVEYFLWLRTQTDRALSAKGLE-DAVHRAISEGP 268 +GV ASPLPGPSGNVEYFLW+R A L+ D V RA++EGP Sbjct 244 LGVLGVTASPLPGPSGNVEYFLWMRA------GAPALDPDDVDRAVAEGP 287 >gi|294628609|ref|ZP_06707169.1| cytotoxin/hemolysin [Streptomyces sp. e14] gi|292831942|gb|EFF90291.1| cytotoxin/hemolysin [Streptomyces sp. e14] Length=271 Score = 290 bits (742), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 175/274 (64%), Positives = 196/274 (72%), Gaps = 13/274 (4%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 VARR R+DAELVRR LARSR+ A++LI AG+V + A KPAT V A+ V TD S+ Sbjct 4 VARR-RLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPATQVETAAAIVVRTDDSD 62 Query 60 RAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +VSRG HKL GALEAF + V GRR LDAGASTGGFT+VLL GAAHVVA DVGYG Sbjct 63 PDYVSRGGHKLAGALEAFVPQGLVVRGRRALDAGASTGGFTDVLLRAGAAHVVAVDVGYG 122 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRDA 175 QLAWSL+ D RV V +RTN R LT EAI G VDLVV DLSFI L VLPALV C DA Sbjct 123 QLAWSLQQDERVTVKDRTNVRELTLEAIDGEPVDLVVGDLSFIPLGLVLPALVRCVRPDA 182 Query 176 DIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSG 235 D+V +VKPQFEVGK ++G GGVV PQLRA +V VA RA ELG GV ASPLPGPSG Sbjct 183 DLVMMVKPQFEVGKERLGSGGVVRSPQLRAEAVRGVAGRAWELGLGVRGVTASPLPGPSG 242 Query 236 NVEYFLWLRTQTDRALSAKGLEDA-VHRAISEGP 268 NVEYFLWLR A L+ A V RA++EGP Sbjct 243 NVEYFLWLRA------GAPALDPADVDRAVAEGP 270 >gi|331697604|ref|YP_004333843.1| hemolysin A [Pseudonocardia dioxanivorans CB1190] gi|326952293|gb|AEA25990.1| hemolysin A [Pseudonocardia dioxanivorans CB1190] Length=266 Score = 289 bits (740), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 160/268 (60%), Positives = 190/268 (71%), Gaps = 3/268 (1%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDSER 60 +A RAR+DAELVRRGLARSR QAAE+I G+V + G+PA K AT + T + V R Sbjct 1 MAVRARLDAELVRRGLARSRAQAAEMIEQGRVVVRGVPAGKAATQIDRDTPVVVAETPGR 60 Query 61 AWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLAW 120 W SRGA KL+GAL+AF + V G RCLDAGASTGGFT+VLLDRGAA VVA DVGYGQL W Sbjct 61 EWASRGAAKLLGALDAFEVDVTGLRCLDAGASTGGFTDVLLDRGAASVVAVDVGYGQLVW 120 Query 121 SLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPALVGCASRDADIVPL 180 LR+D RV V +RTN R LTP+ IGG L VADLSFISL TVLPALV C ++P+ Sbjct 121 RLRSDERVQVHDRTNVRALTPDDIGGPAALTVADLSFISLRTVLPALVACTEPGGTLLPM 180 Query 181 VKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVEYF 240 VKPQFEVG+ ++G GGVV DP LR ++ VA A+E G +G ASPLPGPSGNVEYF Sbjct 181 VKPQFEVGRSRLGSGGVVRDPALRLAALTEVAGAAREAGLRVLGAVASPLPGPSGNVEYF 240 Query 241 LWLRTQTDRALSAKGLEDAVHRAISEGP 268 L L + A +D + RA++EGP Sbjct 241 LRLESGPG---DADAGDDVLARAVAEGP 265 >gi|320011585|gb|ADW06435.1| hemolysin A [Streptomyces flavogriseus ATCC 33331] Length=271 Score = 289 bits (739), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 172/274 (63%), Positives = 198/274 (73%), Gaps = 13/274 (4%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 VARR R+DAELVRR LARSR+ A++LI AG+V + G A KPAT V + A+ VV D S+ Sbjct 4 VARR-RLDAELVRRKLARSREHASQLIAAGRVTVGGNTATKPATQVETSAAVVVVKDDSD 62 Query 60 RAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +VSRG HKL GAL AF + V GRR LDAGASTGGFT+VLL GA HVVA DVGYG Sbjct 63 PEYVSRGGHKLAGALTAFVPLGLEVQGRRALDAGASTGGFTDVLLRAGAGHVVAVDVGYG 122 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRDA 175 QLAWSL++D RV V +RTN R LT E I G+ VDLVV DLSFI L VLPAL CA+ DA Sbjct 123 QLAWSLQSDERVTVKDRTNVRELTLEQIDGKAVDLVVGDLSFIPLGLVLPALARCAAPDA 182 Query 176 DIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSG 235 D+V +VKPQFEVGK ++G GGVV P+LRA +V VARRA LG GV ASPLPGPSG Sbjct 183 DLVLMVKPQFEVGKERLGSGGVVRSPELRAEAVREVARRAGLLGLGVRGVTASPLPGPSG 242 Query 236 NVEYFLWLRTQTDRALSAKGLEDA-VHRAISEGP 268 NVEYFLWLR A L+ A V RA++EGP Sbjct 243 NVEYFLWLRA------GAPELDPADVDRAVAEGP 270 >gi|337764997|emb|CCB73706.1| putative methyltransferase with RNA binding domain [Streptomyces cattleya NRRL 8057] Length=268 Score = 288 bits (738), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 171/271 (64%), Positives = 197/271 (73%), Gaps = 12/271 (4%) Query 4 RARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SERAW 62 R R+DAELVRRGLARSR+ AA+LI AG+V + G A K AT V + AL V D ++ + Sbjct 3 RRRLDAELVRRGLARSREHAAQLIAAGRVTVGGGVAGKAATQVETSAALVVAADDTDPDY 62 Query 63 VSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 VSRG HKL GAL AF + V GR CLDAGASTGGFT+VLL GAA VVA DVGYGQLA Sbjct 63 VSRGGHKLAGALAAFEPLGLTVQGRLCLDAGASTGGFTDVLLRAGAARVVAVDVGYGQLA 122 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRDADIV 178 WSL+ D RVVV +RTN R LT E IGG VDLVV DLSFISL VLPALV CA+ DAD+V Sbjct 123 WSLQKDERVVVKDRTNVRELTLEQIGGEPVDLVVGDLSFISLGLVLPALVRCAAPDADLV 182 Query 179 PLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVE 238 +VKPQFEVGK ++G GGVV QLRA +V VA +A ELG ++GV ASPLPGPSGNVE Sbjct 183 LMVKPQFEVGKERLGSGGVVRSAQLRAEAVRHVAAQAAELGLGALGVTASPLPGPSGNVE 242 Query 239 YFLWLRTQTDRALSAKGLE-DAVHRAISEGP 268 YFLWLR A L+ + V RA++EGP Sbjct 243 YFLWLRA------GAPELDPEDVDRAVAEGP 267 >gi|289772501|ref|ZP_06531879.1| rRNA methylase [Streptomyces lividans TK24] gi|289702700|gb|EFD70129.1| rRNA methylase [Streptomyces lividans TK24] Length=271 Score = 288 bits (738), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 176/275 (64%), Positives = 198/275 (72%), Gaps = 15/275 (5%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVT--DS 58 VARR R+DAELVRR LARSR+ A++LI AG+V + A KPAT V +T A VVT D+ Sbjct 4 VARR-RLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPATQV-ETAAAIVVTADDN 61 Query 59 ERAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGY 115 + +VSRG HKL GAL AF + V GRR LDAGASTGGFT+VLL GAAHVVA DVGY Sbjct 62 DPDYVSRGGHKLAGALAAFVPQGLVVEGRRALDAGASTGGFTDVLLRAGAAHVVAVDVGY 121 Query 116 GQLAWSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRD 174 GQLAWSLR D RV V +RTN R LTPEAI G VDLVV DLSFI LA VLPALV C Sbjct 122 GQLAWSLRQDERVTVKDRTNVRELTPEAIDGEPVDLVVGDLSFIPLALVLPALVRCTRPG 181 Query 175 ADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPS 234 AD+V +VKPQFEVGK ++G GGVV QLRA +V VAR+A ELG GV ASPLPGPS Sbjct 182 ADLVMMVKPQFEVGKERLGSGGVVRSAQLRAEAVRGVARKAWELGLGVKGVTASPLPGPS 241 Query 235 GNVEYFLWLRTQTDRALSAKGLEDA-VHRAISEGP 268 GNVEYFLWLR A L+ A V RA++EGP Sbjct 242 GNVEYFLWLRA------GAGELDPADVDRAVAEGP 270 >gi|328881468|emb|CCA54707.1| RNA binding methyltransferase FtsJ [Streptomyces venezuelae ATCC 10712] Length=271 Score = 288 bits (738), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 171/274 (63%), Positives = 197/274 (72%), Gaps = 13/274 (4%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTD-SE 59 VARR R+DAELVRR LARSR+ A++LI AG+V + A KPAT V A+ VV D S+ Sbjct 4 VARR-RLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPATQVETAAAIVVVQDDSD 62 Query 60 RAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYG 116 +VSRG HKL GA EAF + V GRR LDAGASTGGFT+VLL GAAHVVA DVGYG Sbjct 63 PDYVSRGGHKLAGAFEAFVPLGLKVEGRRALDAGASTGGFTDVLLRAGAAHVVAVDVGYG 122 Query 117 QLAWSLRNDPRVVVLERTNARGLTPEAIGG-RVDLVVADLSFISLATVLPALVGCASRDA 175 QLAWSL++D RV V +RTN R LT +AI G VDLVV DLSFI L VLPAL C + DA Sbjct 123 QLAWSLQSDERVTVKDRTNVRELTLDAIDGVPVDLVVGDLSFIPLGLVLPALAACTAPDA 182 Query 176 DIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSG 235 D+V +VKPQFEVGK ++G GGVV +LRA +V VARRA ELG +GV ASPLPGPSG Sbjct 183 DLVLMVKPQFEVGKERLGTGGVVRSAELRADAVKNVARRAAELGLGVLGVTASPLPGPSG 242 Query 236 NVEYFLWLRTQTDRALSAKGLEDA-VHRAISEGP 268 NVEYFLWLR A L+ A V RA++EGP Sbjct 243 NVEYFLWLRA------GAPALDPADVDRAVAEGP 270 >gi|21220274|ref|NP_626053.1| hypothetical protein SCO1782 [Streptomyces coelicolor A3(2)] gi|5738498|emb|CAB52846.1| putative membrane protein [Streptomyces coelicolor A3(2)] Length=271 Score = 288 bits (736), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 176/275 (64%), Positives = 198/275 (72%), Gaps = 15/275 (5%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVT--DS 58 VARR R+DAELVRR LARSR+ A++LI AG+V + A KPAT V +T A VVT D+ Sbjct 4 VARR-RLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPATQV-ETAAAIVVTADDN 61 Query 59 ERAWVSRGAHKLVGALEAF---AIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGY 115 + +VSRG HKL GAL AF + V GRR LDAGASTGGFT+VLL GAAHVVA DVGY Sbjct 62 DPDYVSRGGHKLAGALAAFVPHGLVVEGRRALDAGASTGGFTDVLLRAGAAHVVAVDVGY 121 Query 116 GQLAWSLRNDPRVVVLERTNARGLTPEAIGGR-VDLVVADLSFISLATVLPALVGCASRD 174 GQLAWSLR D RV V +RTN R LTPEAI G VDLVV DLSFI LA VLPALV C Sbjct 122 GQLAWSLRQDERVTVKDRTNVRELTPEAIDGEPVDLVVGDLSFIPLALVLPALVRCTRPG 181 Query 175 ADIVPLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPS 234 AD+V +VKPQFEVGK ++G GGVV QLRA +V VAR+A ELG GV ASPLPGPS Sbjct 182 ADLVMMVKPQFEVGKERLGSGGVVRSAQLRAEAVRGVARKAWELGLGVKGVTASPLPGPS 241 Query 235 GNVEYFLWLRTQTDRALSAKGLEDA-VHRAISEGP 268 GNVEYFLWLR A L+ A V RA++EGP Sbjct 242 GNVEYFLWLRA------GAGELDPADVDRAVAEGP 270 >gi|297561969|ref|YP_003680943.1| hemolysin A [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296846417|gb|ADH68437.1| hemolysin A [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=266 Score = 286 bits (733), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 167/270 (62%), Positives = 194/270 (72%), Gaps = 7/270 (2%) Query 1 VARRARVDAELVRRGLARSRQQAAELIGAGKVRIDGLPAVKPATAVSDTTALTVVTDS-E 59 +A+R R+DAELVRRG ARSR AAE+I G V++ G+ A K AT V + V S E Sbjct 1 MAKRTRLDAELVRRGHARSRGHAAEIIEGGFVKVAGIVASKAATQVGQDQPIVVRPPSDE 60 Query 60 RAWVSRGAHKLVGALEAFAIAVAGRRCLDAGASTGGFTEVLLDRGAAHVVAADVGYGQLA 119 +VSRGAHKL+GAL+AF VA RR LDAGASTGGFT+VLL R AAHV A DVGYGQLA Sbjct 61 PPYVSRGAHKLIGALDAFEFDVADRRALDAGASTGGFTDVLLRRRAAHVTAVDVGYGQLA 120 Query 120 WSLRNDPRVVVLERTNARGLTPEAIGG-RVDLVVADLSFISLATVLPALVGCASRDADIV 178 WSLR++ RV V+ER N R LTPE IG R DLVV DLSFISL VL AL GC + DAD + Sbjct 121 WSLRSNDRVRVMERVNVRELTPEQIGEPRPDLVVGDLSFISLRLVLGALRGCVAADADFL 180 Query 179 PLVKPQFEVGKGQVGPGGVVHDPQLRARSVLAVARRAQELGWHSVGVKASPLPGPSGNVE 238 +VKPQFEVGK +VG GGVV +P+LRA +V VA A LG +VGV ASPLPGPSGNVE Sbjct 181 LMVKPQFEVGKDKVGAGGVVREPELRAEAVSDVAAHALTLGLGTVGVTASPLPGPSGNVE 240 Query 239 YFLWLRTQTDRALSAKGLEDAVHRAISEGP 268 YFLW+ RA +A DA+ RA+ EGP Sbjct 241 YFLWM-----RAGAAPLDPDALARAVEEGP 265 Lambda K H 0.319 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 410477079682 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40