BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1711 Length=254 Score E Sequences producing significant alignments: (Bits) Value gi|15608849|ref|NP_216227.1| hypothetical protein Rv1711 [Mycoba... 500 7e-140 gi|254231907|ref|ZP_04925234.1| conserved hypothetical protein [... 499 2e-139 gi|340626718|ref|YP_004745170.1| hypothetical protein MCAN_17221... 499 2e-139 gi|289447326|ref|ZP_06437070.1| conserved hypothetical protein [... 497 7e-139 gi|296164607|ref|ZP_06847174.1| ribosomal large subunit pseudour... 434 6e-120 gi|254818897|ref|ZP_05223898.1| ribosomal large subunit pseudour... 433 1e-119 gi|118618582|ref|YP_906914.1| pseudouridylate synthase [Mycobact... 432 2e-119 gi|118465035|ref|YP_882249.1| ribosomal large subunit pseudourid... 431 4e-119 gi|342860716|ref|ZP_08717366.1| ribosomal large subunit pseudour... 431 7e-119 gi|240173130|ref|ZP_04751788.1| ribosomal large subunit pseudour... 429 2e-118 gi|254775517|ref|ZP_05217033.1| ribosomal large subunit pseudour... 429 2e-118 gi|41407511|ref|NP_960347.1| hypothetical protein MAP1413 [Mycob... 428 3e-118 gi|118470853|ref|YP_888039.1| ribosomal large subunit pseudourid... 412 3e-113 gi|108799895|ref|YP_640092.1| ribosomal large subunit pseudourid... 412 4e-113 gi|333990503|ref|YP_004523117.1| pseudouridylate synthase [Mycob... 398 3e-109 gi|120404251|ref|YP_954080.1| pseudouridine synthase [Mycobacter... 396 1e-108 gi|145224079|ref|YP_001134757.1| pseudouridine synthase [Mycobac... 394 8e-108 gi|15827715|ref|NP_301978.1| pseudouridine synthase [Mycobacteri... 383 2e-104 gi|3915542|sp|O05668.1|Y1370_MYCLE RecName: Full=Uncharacterized... 382 3e-104 gi|169629456|ref|YP_001703105.1| l RNA pseudouridine synthase [M... 348 6e-94 gi|262202716|ref|YP_003273924.1| pseudouridine synthase [Gordoni... 342 3e-92 gi|343928409|ref|ZP_08767857.1| putative pseudouridine synthase ... 335 3e-90 gi|326384757|ref|ZP_08206434.1| pseudouridine synthase [Gordonia... 332 3e-89 gi|312139846|ref|YP_004007182.1| pseudouridylate synthase [Rhodo... 328 6e-88 gi|319949182|ref|ZP_08023271.1| pseudouridylate synthase [Dietzi... 327 1e-87 gi|467162|gb|AAA50926.1| u0247g [Mycobacterium leprae] 318 4e-85 gi|325002515|ref|ZP_08123627.1| ribosomal large subunit pseudour... 318 6e-85 gi|296140073|ref|YP_003647316.1| pseudouridine synthase [Tsukamu... 317 1e-84 gi|336325530|ref|YP_004605496.1| ribosomal large subunit pseudou... 313 1e-83 gi|25028115|ref|NP_738169.1| hypothetical protein CE1559 [Coryne... 309 3e-82 gi|68535954|ref|YP_250659.1| putative pseudouridylate synthase [... 308 3e-82 gi|226360073|ref|YP_002777851.1| pseudouridine synthase [Rhodoco... 308 4e-82 gi|111017942|ref|YP_700914.1| pseudouridylate synthase ribosomal... 307 1e-81 gi|213965939|ref|ZP_03394129.1| ribosomal large subunit pseudour... 306 2e-81 gi|331697591|ref|YP_004333830.1| pseudouridine synthase Rsu [Pse... 305 3e-81 gi|333919205|ref|YP_004492786.1| Pseudouridine synthase [Amycoli... 303 1e-80 gi|305680918|ref|ZP_07403725.1| putative pseudouridine synthase ... 303 1e-80 gi|302528005|ref|ZP_07280347.1| pseudouridylate synthase ribosom... 303 2e-80 gi|300787858|ref|YP_003768149.1| ribosomal large subunit pseudou... 303 2e-80 gi|38233785|ref|NP_939552.1| putative pseudouridine synthase B [... 302 4e-80 gi|225021516|ref|ZP_03710708.1| hypothetical protein CORMATOL_01... 301 4e-80 gi|220912302|ref|YP_002487611.1| pseudouridine synthase [Arthrob... 301 5e-80 gi|302330665|gb|ADL20859.1| RNA pseudouridine synthase B [Coryne... 301 6e-80 gi|300858398|ref|YP_003783381.1| hypothetical protein cpfrc_0098... 301 8e-80 gi|226306743|ref|YP_002766703.1| pseudouridine synthase [Rhodoco... 300 1e-79 gi|257056522|ref|YP_003134354.1| ribosomal large subunit pseudou... 300 2e-79 gi|334696769|gb|AEG81566.1| hypothetical protein CULC809_01033 [... 300 2e-79 gi|262182363|ref|ZP_06041784.1| putative pseudouridylate synthas... 300 2e-79 gi|337290656|ref|YP_004629677.1| hypothetical protein CULC22_010... 300 2e-79 gi|227833146|ref|YP_002834853.1| putative pseudouridylate syntha... 299 3e-79 >gi|15608849|ref|NP_216227.1| hypothetical protein Rv1711 [Mycobacterium tuberculosis H37Rv] gi|15841171|ref|NP_336208.1| RNA pseudouridylate synthase [Mycobacterium tuberculosis CDC1551] gi|31792898|ref|NP_855391.1| hypothetical protein Mb1738 [Mycobacterium bovis AF2122/97] 47 more sequence titles Length=254 Score = 500 bits (1288), Expect = 7e-140, Method: Compositional matrix adjust. Identities = 253/254 (99%), Positives = 254/254 (100%), Gaps = 0/254 (0%) Query 1 LMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV 60 +MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV Sbjct 1 MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV 60 Query 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA Sbjct 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 Query 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD Sbjct 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 Query 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL Sbjct 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 Query 241 RSNEIGQLYQAVGL 254 RSNEIGQLYQAVGL Sbjct 241 RSNEIGQLYQAVGL 254 >gi|254231907|ref|ZP_04925234.1| conserved hypothetical protein [Mycobacterium tuberculosis C] gi|254364550|ref|ZP_04980596.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|289554516|ref|ZP_06443726.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 605] 28 more sequence titles Length=253 Score = 499 bits (1284), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 253/253 (100%), Positives = 253/253 (100%), Gaps = 0/253 (0%) Query 2 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV 61 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV Sbjct 1 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV 60 Query 62 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD 121 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD Sbjct 61 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD 120 Query 122 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF 181 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF Sbjct 121 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF 180 Query 182 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR 241 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR Sbjct 181 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR 240 Query 242 SNEIGQLYQAVGL 254 SNEIGQLYQAVGL Sbjct 241 SNEIGQLYQAVGL 253 >gi|340626718|ref|YP_004745170.1| hypothetical protein MCAN_17221 [Mycobacterium canettii CIPT 140010059] gi|340004908|emb|CCC44054.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=254 Score = 499 bits (1284), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 252/254 (99%), Positives = 254/254 (100%), Gaps = 0/254 (0%) Query 1 LMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV 60 +MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIV+GRVEVDGHVVTELGTRVDPQVAV Sbjct 1 MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVNGRVEVDGHVVTELGTRVDPQVAV 60 Query 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA Sbjct 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 Query 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD Sbjct 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 Query 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL Sbjct 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 Query 241 RSNEIGQLYQAVGL 254 RSNEIGQLYQAVGL Sbjct 241 RSNEIGQLYQAVGL 254 >gi|289447326|ref|ZP_06437070.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A] gi|289420284|gb|EFD17485.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A] Length=254 Score = 497 bits (1279), Expect = 7e-139, Method: Compositional matrix adjust. Identities = 252/254 (99%), Positives = 253/254 (99%), Gaps = 0/254 (0%) Query 1 LMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAV 60 +MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDP VAV Sbjct 1 MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPPVAV 60 Query 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA Sbjct 61 VRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDA 120 Query 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD Sbjct 121 DTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDD 180 Query 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL Sbjct 181 FAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRAL 240 Query 241 RSNEIGQLYQAVGL 254 RSNEIGQLYQAVGL Sbjct 241 RSNEIGQLYQAVGL 254 >gi|296164607|ref|ZP_06847174.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900026|gb|EFG79465.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium parascrofulaceum ATCC BAA-614] Length=247 Score = 434 bits (1116), Expect = 6e-120, Method: Compositional matrix adjust. Identities = 216/242 (90%), Positives = 229/242 (95%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVLSQAGIASRRAAEK+I+DGRVEVDG VVTELGTRVDP +V+RVDGARVVLD+ Sbjct 6 GIRLQKVLSQAGIASRRAAEKLIIDGRVEVDGRVVTELGTRVDPDASVIRVDGARVVLDE 65 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 SLVYLALNKPRGMHSTMSDDRGRPCIGDL+ERKVRG K LFHVGRLDADTEGL+LLTNDG Sbjct 66 SLVYLALNKPRGMHSTMSDDRGRPCIGDLVERKVRGNKNLFHVGRLDADTEGLILLTNDG 125 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPSHEVPKTYLATVTGSVPRG+G+ L+AGIELDDGPA VDDFAVVDAIPGKTL Sbjct 126 ELAHRLMHPSHEVPKTYLATVTGSVPRGIGKKLKAGIELDDGPARVDDFAVVDAIPGKTL 185 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRV LHEGRNRIVRRLL AAGFPVEALVRTDIG VSLGKQRPGS+RAL E+GQLY+AV Sbjct 186 VRVVLHEGRNRIVRRLLGAAGFPVEALVRTDIGPVSLGKQRPGSIRALNQGEVGQLYKAV 245 Query 253 GL 254 GL Sbjct 246 GL 247 >gi|254818897|ref|ZP_05223898.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium intracellulare ATCC 13950] Length=247 Score = 433 bits (1114), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 218/245 (89%), Positives = 232/245 (95%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E GIRLQKVLSQAGIASRRAAEK+I++GRVEVDG VVTELGTRVDP V+V+RVDGAR+V Sbjct 3 EAEGIRLQKVLSQAGIASRRAAEKLIIEGRVEVDGQVVTELGTRVDPDVSVIRVDGARIV 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LDDS VYLALNKPRG+HSTMSDDRGRPCIGDLIER+VRG K LFHVGRLDADTEGL+LLT Sbjct 63 LDDSQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDADTEGLILLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPSHEVPKTYLATVTGSVPRG+G+ LRAGIELDDGPA VD+FAVVDAIPG Sbjct 123 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGVGKALRAGIELDDGPARVDEFAVVDAIPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIG VSLGKQRPGS RAL +EIGQLY Sbjct 183 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGPVSLGKQRPGSFRALGRDEIGQLY 242 Query 250 QAVGL 254 +AVGL Sbjct 243 KAVGL 247 >gi|118618582|ref|YP_906914.1| pseudouridylate synthase [Mycobacterium ulcerans Agy99] gi|183982541|ref|YP_001850832.1| pseudouridylate synthase [Mycobacterium marinum M] gi|118570692|gb|ABL05443.1| pseudouridylate synthase [Mycobacterium ulcerans Agy99] gi|183175867|gb|ACC40977.1| pseudouridylate synthase [Mycobacterium marinum M] Length=253 Score = 432 bits (1112), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 215/253 (85%), Positives = 233/253 (93%), Gaps = 0/253 (0%) Query 2 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV 61 M + E+ + RGIRLQKVLSQAGIASRRAAEK+I+DGRVEVDG VVTELGTRVDP +++ Sbjct 1 MTDTEDFEQERGIRLQKVLSQAGIASRRAAEKLIIDGRVEVDGQVVTELGTRVDPDTSLI 60 Query 62 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD 121 RVDG RV+LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRG K LFHVGRLDAD Sbjct 61 RVDGVRVILDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGNKNLFHVGRLDAD 120 Query 122 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF 181 TEGL+LLTNDGELAHRLMHPSHEVPKTYLATV G+VPRGLG+ LRAGIEL+DGP VD F Sbjct 121 TEGLILLTNDGELAHRLMHPSHEVPKTYLATVAGTVPRGLGKKLRAGIELEDGPVRVDGF 180 Query 182 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR 241 AVVDAIPGKTLVRVTLHEGRNRIVRR+LAA GFPV+ALVR DIG VSLG+QRPGSVRALR Sbjct 181 AVVDAIPGKTLVRVTLHEGRNRIVRRMLAAVGFPVQALVRIDIGGVSLGEQRPGSVRALR 240 Query 242 SNEIGQLYQAVGL 254 +EIGQLY+AVGL Sbjct 241 RDEIGQLYKAVGL 253 >gi|118465035|ref|YP_882249.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium avium 104] gi|118166322|gb|ABK67219.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium avium 104] Length=248 Score = 431 bits (1109), Expect = 4e-119, Method: Compositional matrix adjust. Identities = 216/245 (89%), Positives = 233/245 (96%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E +GIRLQKVLSQAGIASRRAAEK+IVDGRVEVDG VVTELGTRVDP AV+RVDGARVV Sbjct 4 EAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVV 63 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LD+S VYLALNKPRG+HSTMSDDRGRPCIGDLIER+VRG K LFHVGRLDA+TEGL+LLT Sbjct 64 LDESQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLT 123 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPSHEVPKTYLATVTGS+PRGLG+TLRAGIELDDG A VD+FAVVDAIPG Sbjct 124 NDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDAIPG 183 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KTLVRVTLHEGRNRIVRRLLAAAGFPVE+LVRTDIG +SLGKQRPGS+RAL +E+G+LY Sbjct 184 KTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGRLY 243 Query 250 QAVGL 254 QAVGL Sbjct 244 QAVGL 248 >gi|342860716|ref|ZP_08717366.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium colombiense CECT 3035] gi|342131740|gb|EGT84997.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium colombiense CECT 3035] Length=247 Score = 431 bits (1107), Expect = 7e-119, Method: Compositional matrix adjust. Identities = 217/245 (89%), Positives = 231/245 (95%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E +GIRLQKVLSQAGIASRRAAEK+I+DGRVEVDG VVTELGTRVDP AV+RVDGARVV Sbjct 3 EAQGIRLQKVLSQAGIASRRAAEKLIIDGRVEVDGQVVTELGTRVDPDSAVIRVDGARVV 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LDDS VYLALNKPRG+HSTMSDDRGRPCIGDL+ERKVRG K LFHVGRLDADTEGL+LLT Sbjct 63 LDDSQVYLALNKPRGVHSTMSDDRGRPCIGDLVERKVRGNKNLFHVGRLDADTEGLILLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLG+ LRAGIEL+DG A VD+FAVVDAIPG Sbjct 123 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGKKLRAGIELEDGVARVDEFAVVDAIPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KTLVRVTLHEGRNRIVRRLLAAAGFPVE+LVRTDIG VSLGKQRPG+ RAL +EIGQLY Sbjct 183 KTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPVSLGKQRPGTFRALAHHEIGQLY 242 Query 250 QAVGL 254 +AVGL Sbjct 243 KAVGL 247 >gi|240173130|ref|ZP_04751788.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium kansasii ATCC 12478] Length=250 Score = 429 bits (1104), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 220/249 (89%), Positives = 232/249 (94%), Gaps = 1/249 (0%) Query 6 EESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDG 65 E R P GIRLQKVLSQAGIASRRAAEKMI+DGRVEVDG +VTELGTRVDP V+V+RVDG Sbjct 3 ELGRSP-GIRLQKVLSQAGIASRRAAEKMIIDGRVEVDGKLVTELGTRVDPDVSVIRVDG 61 Query 66 ARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGL 125 ARVVLD+SLVYLALNKPRGMHSTM+DDRGRPCIGDLIERKVRG K LFHVGRLDADTEGL Sbjct 62 ARVVLDESLVYLALNKPRGMHSTMADDRGRPCIGDLIERKVRGNKNLFHVGRLDADTEGL 121 Query 126 MLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVD 185 +LLTNDGELAHRLMHPSHEVPKTYLATV G+VPRGLG+ LR GIELDDG A VD FAVVD Sbjct 122 ILLTNDGELAHRLMHPSHEVPKTYLATVAGTVPRGLGKKLRTGIELDDGLARVDGFAVVD 181 Query 186 AIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEI 245 AIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIG V+LGKQRPGSVRAL +EI Sbjct 182 AIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGPVTLGKQRPGSVRALGRDEI 241 Query 246 GQLYQAVGL 254 GQLY+AVGL Sbjct 242 GQLYKAVGL 250 >gi|254775517|ref|ZP_05217033.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium avium subsp. avium ATCC 25291] Length=247 Score = 429 bits (1102), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 215/245 (88%), Positives = 232/245 (95%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E +GIRLQKVLSQAGIASRRAAEK+IVDGRVEVDG VVTELGTRVDP AV+RVDGARVV Sbjct 3 EAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVV 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LD+S VYLALNKPRG+HSTMSDDRGRPCIGDLIER+VRG K LFHVGRLDA+TEGL+LLT Sbjct 63 LDESQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPSHEVPKTYLATVTGS+PRGLG+TLRAGIELDDG A VD+FAVVDA PG Sbjct 123 NDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDATPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KTLVRVTLHEGRNRIVRRLLAAAGFPVE+LVRTDIG +SLGKQRPGS+RAL +E+G+LY Sbjct 183 KTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGRLY 242 Query 250 QAVGL 254 QAVGL Sbjct 243 QAVGL 247 >gi|41407511|ref|NP_960347.1| hypothetical protein MAP1413 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395864|gb|AAS03730.1| hypothetical protein MAP_1413 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457865|gb|EGO36859.1| pseudouridine synthase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=247 Score = 428 bits (1101), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 215/245 (88%), Positives = 232/245 (95%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E +GIRLQKVLSQAGIASRRAAEK+IVDGRVEVDG VVTELGTRVDP AV+RVDGARVV Sbjct 3 EAQGIRLQKVLSQAGIASRRAAEKLIVDGRVEVDGQVVTELGTRVDPDAAVIRVDGARVV 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LD+S VYLALNKPRG+HSTMSDDRGRPCIGDLIER+VRG K LFHVGRLDA+TEGL+LLT Sbjct 63 LDESQVYLALNKPRGVHSTMSDDRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPSHEVPKTYLATVTGS+PRGLG+TLRAGIELDDG A VD+FAVVD IPG Sbjct 123 NDGELAHRLMHPSHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDPIPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KTLVRVTLHEGRNRIVRRLLAAAGFPVE+LVRTDIG +SLGKQRPGS+RAL +E+G+LY Sbjct 183 KTLVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALGRDEVGRLY 242 Query 250 QAVGL 254 QAVGL Sbjct 243 QAVGL 247 >gi|118470853|ref|YP_888039.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium smegmatis str. MC2 155] gi|118172140|gb|ABK73036.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium smegmatis str. MC2 155] Length=247 Score = 412 bits (1058), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 196/245 (80%), Positives = 226/245 (93%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 E +G+RLQKVLSQAGIASRR AE+MI+DGRVEVDG +VTELGTRVDP VA +RVDG+R++ Sbjct 3 EEQGVRLQKVLSQAGIASRRVAERMIIDGRVEVDGQIVTELGTRVDPAVADIRVDGSRII 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LDD++VYLA+NKPRGMHSTMSDDRGRPC+GDL+E +VRG KKLFHVGRLDADTEGL+LLT Sbjct 63 LDDTMVYLAINKPRGMHSTMSDDRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPS EVPKTY+ATV G+VPRGLG+ L+AG+ELDDGPA VDDFAVVD +PG Sbjct 123 NDGELAHRLMHPSFEVPKTYVATVMGTVPRGLGKKLKAGVELDDGPAHVDDFAVVDTVPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 KT+V+VTLHEGRNRIVRRLLAA FPV+ LVRT+IG+VSLG QRPGS+RAL E+G+LY Sbjct 183 KTMVKVTLHEGRNRIVRRLLAAVDFPVQELVRTEIGSVSLGDQRPGSIRALTRKEVGELY 242 Query 250 QAVGL 254 QAVGL Sbjct 243 QAVGL 247 >gi|108799895|ref|YP_640092.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. MCS] gi|119869005|ref|YP_938957.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. KMS] gi|126435523|ref|YP_001071214.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. JLS] gi|108770314|gb|ABG09036.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. MCS] gi|119695094|gb|ABL92167.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. KMS] gi|126235323|gb|ABN98723.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. JLS] Length=247 Score = 412 bits (1058), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 201/245 (83%), Positives = 226/245 (93%), Gaps = 0/245 (0%) Query 10 EPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVV 69 EP G+RLQKVLSQAGIASRR AEKMI+DGRVEVDGH+VTELGTRVDP A +RVDG RV+ Sbjct 3 EPDGVRLQKVLSQAGIASRRVAEKMILDGRVEVDGHIVTELGTRVDPTAADIRVDGTRVL 62 Query 70 LDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLT 129 LDD+LV+LA+NKPRGMHSTMSDDRGRPCIGDL+E +VRG K LFHVGRLDADTEGLMLLT Sbjct 63 LDDTLVHLAINKPRGMHSTMSDDRGRPCIGDLVEHRVRGNKGLFHVGRLDADTEGLMLLT 122 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGELAHRLMHPS+EVPKTY+ATV G+VPRGLG+ LRAG+ELDDGPA VDDFAVVDA+PG Sbjct 123 NDGELAHRLMHPSYEVPKTYVATVLGTVPRGLGKKLRAGVELDDGPARVDDFAVVDAMPG 182 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 +++VRVTLHEGR RIVRRLLAA GFPV+ LVRTDIGAVSLG+QRPGS+R L EIG+LY Sbjct 183 RSMVRVTLHEGRKRIVRRLLAAVGFPVQELVRTDIGAVSLGEQRPGSIRVLTRKEIGELY 242 Query 250 QAVGL 254 +AVG+ Sbjct 243 KAVGM 247 >gi|333990503|ref|YP_004523117.1| pseudouridylate synthase [Mycobacterium sp. JDM601] gi|333486471|gb|AEF35863.1| pseudouridylate synthase [Mycobacterium sp. JDM601] Length=253 Score = 398 bits (1023), Expect = 3e-109, Method: Compositional matrix adjust. Identities = 198/253 (79%), Positives = 221/253 (88%), Gaps = 0/253 (0%) Query 2 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV 61 MA + + G+RLQKVLSQAG+ASRR AEKMI DGRVEVDG VVTELGTRVDP +V+ Sbjct 1 MAFSDFQPDAEGVRLQKVLSQAGVASRRVAEKMIRDGRVEVDGQVVTELGTRVDPAASVI 60 Query 62 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD 121 RVDGARV +DD+ VYLALNKPRG+HSTMSDDRGRPCIGD +E +VRG KLFHVGRLDAD Sbjct 61 RVDGARVSVDDTRVYLALNKPRGVHSTMSDDRGRPCIGDYVEHRVRGDAKLFHVGRLDAD 120 Query 122 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF 181 TEGLMLLTNDGELAHRLMHPS VPKTY+ATV GSVPRGLG+ LR G+ELDDGPA VDDF Sbjct 121 TEGLMLLTNDGELAHRLMHPSFRVPKTYVATVLGSVPRGLGKKLREGVELDDGPAKVDDF 180 Query 182 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR 241 AVVDA+PGK+LVRVTLHEGR RIVRR+LAA GFPV+ LVRTDIGAV+LG+QRPG++R L Sbjct 181 AVVDAVPGKSLVRVTLHEGRKRIVRRMLAAVGFPVQELVRTDIGAVALGEQRPGTIRVLN 240 Query 242 SNEIGQLYQAVGL 254 EIG+LY AVGL Sbjct 241 RKEIGELYTAVGL 253 >gi|120404251|ref|YP_954080.1| pseudouridine synthase [Mycobacterium vanbaalenii PYR-1] gi|119957069|gb|ABM14074.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium vanbaalenii PYR-1] Length=247 Score = 396 bits (1018), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 194/242 (81%), Positives = 215/242 (89%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVLSQAGIASRR AEKMI DGRVEVDG +VTELGTRVDP +V+RVDGAR+ +DD Sbjct 6 GIRLQKVLSQAGIASRRVAEKMIRDGRVEVDGRIVTELGTRVDPAASVIRVDGARITVDD 65 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 +LVYLA+NKPRGMHSTMSDDRGRPC+GDL+E +VRG KKLFHVGRLDADTEGL+LLTNDG Sbjct 66 TLVYLAINKPRGMHSTMSDDRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDG 125 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPS EVPK+Y+ATV GSVP+GLGR LR G+EL+DGP VDDFAVVD PG+TL Sbjct 126 ELAHRLMHPSFEVPKSYVATVLGSVPKGLGRKLREGVELEDGPVQVDDFAVVDTTPGRTL 185 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRVTLHEGR IVRRLLA GFPV+ LVRTDIG VSLG QRPGS+R L EIG+LY+AV Sbjct 186 VRVTLHEGRKHIVRRLLAEVGFPVQELVRTDIGTVSLGDQRPGSIRVLTQKEIGELYKAV 245 Query 253 GL 254 GL Sbjct 246 GL 247 >gi|145224079|ref|YP_001134757.1| pseudouridine synthase [Mycobacterium gilvum PYR-GCK] gi|315444416|ref|YP_004077295.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. Spyr1] gi|145216565|gb|ABP45969.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium gilvum PYR-GCK] gi|315262719|gb|ADT99460.1| ribosomal large subunit pseudouridine synthase B [Mycobacterium sp. Spyr1] Length=247 Score = 394 bits (1012), Expect = 8e-108, Method: Compositional matrix adjust. Identities = 193/242 (80%), Positives = 216/242 (90%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVLSQAGIASRR AEKMI DGRVEVD +VTELGTRVDP +V+RVDGAR+ +DD Sbjct 6 GVRLQKVLSQAGIASRRVAEKMIRDGRVEVDDRIVTELGTRVDPAESVIRVDGARITVDD 65 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 +LV+LA+NKPRGMHSTMSDDRGRPC+GDL+E +VRG KKLFHVGRLDADTEGL+LLTNDG Sbjct 66 TLVHLAINKPRGMHSTMSDDRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDG 125 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPS+EVPK+Y+ATV GSVPRGLGR LR G+ELDDGP VDDFA+VD PG+TL Sbjct 126 ELAHRLMHPSYEVPKSYVATVLGSVPRGLGRKLREGVELDDGPVQVDDFALVDTTPGRTL 185 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRVTLHEGR IVRRLLA GFPV+ LVRTDIG VSLG QRPGS+RAL EIG+LY+AV Sbjct 186 VRVTLHEGRKHIVRRLLAEVGFPVQNLVRTDIGGVSLGDQRPGSIRALTQKEIGELYKAV 245 Query 253 GL 254 GL Sbjct 246 GL 247 >gi|15827715|ref|NP_301978.1| pseudouridine synthase [Mycobacterium leprae TN] gi|221230192|ref|YP_002503608.1| putative pseudouridine synthase [Mycobacterium leprae Br4923] gi|13093266|emb|CAC31751.1| possible pseudouridine synthase [Mycobacterium leprae] gi|219933299|emb|CAR71465.1| possible pseudouridine synthase [Mycobacterium leprae Br4923] Length=257 Score = 383 bits (983), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 206/257 (81%), Positives = 229/257 (90%), Gaps = 3/257 (1%) Query 1 LMAEPEESREPRG---IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQ 57 +M E +SR RG +RLQK+LS+AGIASRRAAEK+I++GRVEVDG +V ELGTRVDP Sbjct 1 MMVEIHDSRMDRGAGAVRLQKILSRAGIASRRAAEKLIIEGRVEVDGQLVRELGTRVDPD 60 Query 58 VAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGR 117 V+VVRVDG +VV+DDSLVYLALNKPRGM+STMSDDRGRPC+GDLIER+VRG KKLFHVGR Sbjct 61 VSVVRVDGVKVVVDDSLVYLALNKPRGMYSTMSDDRGRPCVGDLIERRVRGNKKLFHVGR 120 Query 118 LDADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAF 177 LDADTEGL+LLTNDGELAHRLMHPSHEV KTYLATV G+VPRGLG+ L G+ELDDGPA Sbjct 121 LDADTEGLILLTNDGELAHRLMHPSHEVSKTYLATVKGAVPRGLGKKLSVGLELDDGPAH 180 Query 178 VDDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSV 237 VDDFAVVDAIPGKTLVR+TLHEGR RIVRRLL AAGFPVE LVRTDIGAVSLG QRPG + Sbjct 181 VDDFAVVDAIPGKTLVRLTLHEGRKRIVRRLLTAAGFPVEMLVRTDIGAVSLGDQRPGCL 240 Query 238 RALRSNEIGQLYQAVGL 254 RAL +EI QLY+ VGL Sbjct 241 RALLRDEIRQLYKEVGL 257 >gi|3915542|sp|O05668.1|Y1370_MYCLE RecName: Full=Uncharacterized RNA pseudouridine synthase ML1370; AltName: Full=RNA pseudouridylate synthase; AltName: Full=RNA-uridine isomerase gi|2065214|emb|CAB08276.1| unnamed protein product [Mycobacterium leprae] Length=256 Score = 382 bits (981), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 206/256 (81%), Positives = 228/256 (90%), Gaps = 3/256 (1%) Query 2 MAEPEESREPRG---IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQV 58 M E +SR RG +RLQK+LS+AGIASRRAAEK+I++GRVEVDG +V ELGTRVDP V Sbjct 1 MVEIHDSRMDRGAGAVRLQKILSRAGIASRRAAEKLIIEGRVEVDGQLVRELGTRVDPDV 60 Query 59 AVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRL 118 +VVRVDG +VV+DDSLVYLALNKPRGM+STMSDDRGRPC+GDLIER+VRG KKLFHVGRL Sbjct 61 SVVRVDGVKVVVDDSLVYLALNKPRGMYSTMSDDRGRPCVGDLIERRVRGNKKLFHVGRL 120 Query 119 DADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFV 178 DADTEGL+LLTNDGELAHRLMHPSHEV KTYLATV G+VPRGLG+ L G+ELDDGPA V Sbjct 121 DADTEGLILLTNDGELAHRLMHPSHEVSKTYLATVKGAVPRGLGKKLSVGLELDDGPAHV 180 Query 179 DDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVR 238 DDFAVVDAIPGKTLVR+TLHEGR RIVRRLL AAGFPVE LVRTDIGAVSLG QRPG +R Sbjct 181 DDFAVVDAIPGKTLVRLTLHEGRKRIVRRLLTAAGFPVEMLVRTDIGAVSLGDQRPGCLR 240 Query 239 ALRSNEIGQLYQAVGL 254 AL +EI QLY+ VGL Sbjct 241 ALLRDEIRQLYKEVGL 256 >gi|169629456|ref|YP_001703105.1| l RNA pseudouridine synthase [Mycobacterium abscessus ATCC 19977] gi|169241423|emb|CAM62451.1| Probablel RNA pseudouridine synthase [Mycobacterium abscessus] Length=263 Score = 348 bits (892), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 174/248 (71%), Positives = 205/248 (83%), Gaps = 0/248 (0%) Query 7 ESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGA 66 E+ GIRLQKVLSQAGIASRR AE+MI DGRVEVDG +VTE G R+DP V VVRVDGA Sbjct 16 ETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQGRRIDPAVNVVRVDGA 75 Query 67 RVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLM 126 RV+++ LVYLALNKP GM STMSDDRGRPC+G LIE +VRG + + +VGRLDADT GL+ Sbjct 76 RVIMNTDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQGVRNVGRLDADTVGLI 135 Query 127 LLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDA 186 LLTNDGEL HRLMHPS+EVPKTY+ATV G++PRGLGR LR G+EL DGPA VD+F + Sbjct 136 LLTNDGELTHRLMHPSYEVPKTYIATVAGTIPRGLGRQLRDGVELADGPAKVDEFKFLGT 195 Query 187 IPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIG 246 G+++V++TLHEGRNRIVRR++ AAG PV LVRT IG V+LG QRPGS+RAL +EIG Sbjct 196 TDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGNQRPGSLRALGRDEIG 255 Query 247 QLYQAVGL 254 LY+AVGL Sbjct 256 SLYKAVGL 263 >gi|262202716|ref|YP_003273924.1| pseudouridine synthase [Gordonia bronchialis DSM 43247] gi|262086063|gb|ACY22031.1| pseudouridine synthase [Gordonia bronchialis DSM 43247] Length=329 Score = 342 bits (878), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 162/242 (67%), Positives = 201/242 (84%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AE+MI GRVE+DG +VTE G R+DP A++RVDGARV++D+ Sbjct 88 GVRLQKVLAQAGVASRRGAEEMIAAGRVEIDGEIVTEQGLRIDPDTAIIRVDGARVIIDE 147 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + YLALNKPRG STM+DD+GRPC+GD++ +V ++LFHVGRLDADTEGL+LLTNDG Sbjct 148 TRQYLALNKPRGWQSTMADDQGRPCVGDIVAERVMAGQRLFHVGRLDADTEGLLLLTNDG 207 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPS+EVPKTYLATV G VPR L R LR G+ELDDGP VD +VD G++L Sbjct 208 ELAHRLMHPSYEVPKTYLATVRGEVPRSLSRMLRDGVELDDGPVAVDKLTIVDVHEGQSL 267 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+TLHEGRNRIVRR++ GFPV LVRT +G+V+LG+QRPGS+R L +E+G LY+AV Sbjct 268 LRITLHEGRNRIVRRMMDEVGFPVVELVRTHVGSVALGEQRPGSLRVLGRDEVGALYKAV 327 Query 253 GL 254 GL Sbjct 328 GL 329 >gi|343928409|ref|ZP_08767857.1| putative pseudouridine synthase [Gordonia alkanivorans NBRC 16433] gi|343761594|dbj|GAA14783.1| putative pseudouridine synthase [Gordonia alkanivorans NBRC 16433] Length=311 Score = 335 bits (860), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 159/242 (66%), Positives = 199/242 (83%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AE+MI GRV+VDG VVTE G R++P A++ VD ARV++D+ Sbjct 70 GVRLQKVLAQAGVASRRGAEEMIAAGRVKVDGKVVTEQGLRINPDTAIIHVDDARVIMDE 129 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + YLA NKP+G STM+DD+GRPC+GD++ +V ++LFHVGRLDADTEGL+LLTNDG Sbjct 130 TKQYLAFNKPKGWQSTMADDQGRPCVGDVVAERVMAGQRLFHVGRLDADTEGLLLLTNDG 189 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPS EVPKTYLAT+ G VPRG+ R LR GIEL+DGP VD F V++ G++L Sbjct 190 ELAHRLMHPSFEVPKTYLATLKGEVPRGIARHLREGIELEDGPVKVDKFTVIEVHEGQSL 249 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VR+TLHEGRNRIVRR++ GFPV LVRT +G V+LG+QRPGS+R L S+E+G LY+AV Sbjct 250 VRITLHEGRNRIVRRMMDEVGFPVTKLVRTHVGTVALGEQRPGSLRVLGSDEVGGLYKAV 309 Query 253 GL 254 GL Sbjct 310 GL 311 >gi|326384757|ref|ZP_08206434.1| pseudouridine synthase [Gordonia neofelifaecis NRRL B-59395] gi|326196565|gb|EGD53762.1| pseudouridine synthase [Gordonia neofelifaecis NRRL B-59395] Length=362 Score = 332 bits (852), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 171/242 (71%), Positives = 203/242 (84%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+ AG+ASRR AE++I GRVEVDG VV E G R+DP A+++VDGARVV+D+ Sbjct 121 GMRLQKVLAAAGVASRRGAEELIAAGRVEVDGEVVVEQGLRIDPDTAIIKVDGARVVIDE 180 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 S YLALNKP+G HSTMSDD+GRPCIGD+I +V ++LFHVGRLDADTEGL+LLTNDG Sbjct 181 SKQYLALNKPKGWHSTMSDDQGRPCIGDIIAERVMAGQRLFHVGRLDADTEGLLLLTNDG 240 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELAHRLMHPS+EVPKTYLATV G V RGLGR LR G+EL+DGP VD FA+++ GK+L Sbjct 241 ELAHRLMHPSYEVPKTYLATVRGEVNRGLGRELRQGVELEDGPVAVDSFALLEVNQGKSL 300 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VR+TLHEGR R+VRRLLA GFPV LVRTDIG V+LGKQRPGS+R L + EIG LY+AV Sbjct 301 VRLTLHEGRKRVVRRLLAEVGFPVVGLVRTDIGPVTLGKQRPGSLRVLDNKEIGALYKAV 360 Query 253 GL 254 G+ Sbjct 361 GM 362 >gi|312139846|ref|YP_004007182.1| pseudouridylate synthase [Rhodococcus equi 103S] gi|325674277|ref|ZP_08153966.1| ribosomal large subunit pseudouridine synthase B [Rhodococcus equi ATCC 33707] gi|311889185|emb|CBH48499.1| pseudouridylate synthase [Rhodococcus equi 103S] gi|325554957|gb|EGD24630.1| ribosomal large subunit pseudouridine synthase B [Rhodococcus equi ATCC 33707] Length=321 Score = 328 bits (840), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 166/242 (69%), Positives = 196/242 (81%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRRAAE++I GRVEVDG +V E G RVDP+ A+VRVDG RVV+ Sbjct 80 GVRLQKVLAQAGVASRRAAEELIDQGRVEVDGRIVLEQGLRVDPENAIVRVDGIRVVVKK 139 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 LV++ALNKPRG STMSDD GRPCIGD++ +V ++LFHVGRLDADTEGL+LLTNDG Sbjct 140 DLVHIALNKPRGWQSTMSDDLGRPCIGDIVSERVSAGQRLFHVGRLDADTEGLILLTNDG 199 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 +LAHRLMHPS+EVPKTYLATV G V R +G+TL+AG+ELDDGPA VD F ++D GK+L Sbjct 200 DLAHRLMHPSYEVPKTYLATVQGVVDRNVGKTLKAGVELDDGPAKVDAFTLLDVNGGKSL 259 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRV LHEGR IVRRLL A G PV LVRTDIG V+LG RPG++R L E+G LY AV Sbjct 260 VRVVLHEGRKHIVRRLLEAVGHPVVRLVRTDIGNVALGDGRPGTLRVLGRGEVGGLYGAV 319 Query 253 GL 254 GL Sbjct 320 GL 321 >gi|319949182|ref|ZP_08023271.1| pseudouridylate synthase [Dietzia cinnamea P4] gi|319437168|gb|EFV92199.1| pseudouridylate synthase [Dietzia cinnamea P4] Length=252 Score = 327 bits (838), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 156/241 (65%), Positives = 198/241 (83%), Gaps = 0/241 (0%) Query 14 IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDS 73 +RLQK+L+QAG+ASRRA+E +I GRVEVDG +V E+G +VDP AV+RVDG R+VLDD+ Sbjct 12 VRLQKILAQAGVASRRASEDLIARGRVEVDGKIVREMGVKVDPATAVIRVDGTRIVLDDT 71 Query 74 LVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGE 133 LV+LALNKPRG H+TMSD+ GRPC+GDL+ ++ ++LFHVGRLDADTEGL+L+TNDGE Sbjct 72 LVHLALNKPRGYHTTMSDEMGRPCVGDLVADRIDAGQRLFHVGRLDADTEGLLLVTNDGE 131 Query 134 LAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLV 193 LAHRLMHPS+EV KTY+ATVTG V +G+G+ LR G+EL+DGPA VD F+++D G++LV Sbjct 132 LAHRLMHPSYEVSKTYMATVTGVVGKGIGKQLREGVELEDGPAKVDQFSLLDVHDGRSLV 191 Query 194 RVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVG 253 +V LHEGR IVRRLLA G PVE+LVRT G+V+LG QR G+ R L E+ LY+AVG Sbjct 192 KVVLHEGRKHIVRRLLAEVGHPVESLVRTRFGSVALGDQRAGTFRKLNRREVSDLYEAVG 251 Query 254 L 254 L Sbjct 252 L 252 >gi|467162|gb|AAA50926.1| u0247g [Mycobacterium leprae] Length=186 Score = 318 bits (816), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 157/186 (85%), Positives = 170/186 (92%), Gaps = 0/186 (0%) Query 69 VLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLL 128 ++DDSLVYLALNKPRGM+STMSDDRGRPC+GDLIER+VRG KKLFHVGRLDADTEGL+LL Sbjct 1 MVDDSLVYLALNKPRGMYSTMSDDRGRPCVGDLIERRVRGNKKLFHVGRLDADTEGLILL 60 Query 129 TNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIP 188 TNDGELAHRLMHPSHEV KTYLATV G+VPRGLG+ L G+ELDDGPA VDDFAVVDAIP Sbjct 61 TNDGELAHRLMHPSHEVSKTYLATVKGAVPRGLGKKLSVGLELDDGPAHVDDFAVVDAIP 120 Query 189 GKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQL 248 GKTLVR+TLHEGR RIVRRLL AAGFPVE LVRTDIGAVSLG QRPG +RAL +EI QL Sbjct 121 GKTLVRLTLHEGRKRIVRRLLTAAGFPVEMLVRTDIGAVSLGDQRPGCLRALLRDEIRQL 180 Query 249 YQAVGL 254 Y+ VGL Sbjct 181 YKEVGL 186 >gi|325002515|ref|ZP_08123627.1| ribosomal large subunit pseudouridine synthase B [Pseudonocardia sp. P1] Length=253 Score = 318 bits (814), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 159/250 (64%), Positives = 196/250 (79%), Gaps = 3/250 (1%) Query 8 SREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGAR 67 + +P G+RLQKVL++AG+ASRRAAE++I GRV+VDG V E+G R+DP+ AV+ VDGAR Sbjct 4 AHDPDGVRLQKVLARAGVASRRAAEELIAQGRVQVDGETVREMGRRIDPETAVLHVDGAR 63 Query 68 VVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKV---RGTKKLFHVGRLDADTEG 124 V L D VYLALNKP G+HSTMSDD GRPC+GDL+ +V ++LFHVGRLDADTEG Sbjct 64 VTLRDDQVYLALNKPVGLHSTMSDDLGRPCVGDLLADRVELMNSAQRLFHVGRLDADTEG 123 Query 125 LMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVV 184 L+LLTNDGEL HRLMHPS+EVPKTYLA V G + R LGR LR GIEL+DG A VD F +V Sbjct 124 LLLLTNDGELGHRLMHPSYEVPKTYLAEVEGKIARDLGRRLRDGIELEDGIARVDAFKLV 183 Query 185 DAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNE 244 DA+PG++ V++ LHEGR IVRR+L+ G PV+ LVRT +G V LG Q+PG +R L E Sbjct 184 DAVPGRSTVQLILHEGRKHIVRRMLSEVGHPVQRLVRTAVGEVRLGNQKPGKLRPLDRVE 243 Query 245 IGQLYQAVGL 254 +G LY+AVGL Sbjct 244 VGSLYKAVGL 253 >gi|296140073|ref|YP_003647316.1| pseudouridine synthase [Tsukamurella paurometabola DSM 20162] gi|296028207|gb|ADG78977.1| pseudouridine synthase [Tsukamurella paurometabola DSM 20162] Length=319 Score = 317 bits (811), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 167/241 (70%), Positives = 200/241 (83%), Gaps = 0/241 (0%) Query 14 IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDS 73 IRLQKVL+QAG+ASRR AE+MI DGRVEVDG +VTE G RVDP VAVVRVDG RVV++++ Sbjct 79 IRLQKVLAQAGVASRRVAEEMIADGRVEVDGEIVTEQGLRVDPSVAVVRVDGVRVVVNEN 138 Query 74 LVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGE 133 LV+LALNKPRG HSTMSDD GRPC+GD++ +V ++LFHVGRLDADTEGL+L+TNDGE Sbjct 139 LVHLALNKPRGWHSTMSDDMGRPCVGDIVAERVAAGQRLFHVGRLDADTEGLLLVTNDGE 198 Query 134 LAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLV 193 LAHRLMHPS+EVPKTYLA V G VPR LG+ LR G+EL+DGP VD F+V++A GK+ V Sbjct 199 LAHRLMHPSYEVPKTYLAWVAGEVPRNLGKKLRDGVELEDGPVTVDRFSVLEAAEGKSTV 258 Query 194 RVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVG 253 RV LHEGR IVRRLLA G PV+ LVRT +G V+LG QRPGS+R L +E+ LY+AVG Sbjct 259 RVVLHEGRKHIVRRLLAEVGHPVQRLVRTHVGTVALGDQRPGSLRVLGRDEVESLYKAVG 318 Query 254 L 254 + Sbjct 319 M 319 >gi|336325530|ref|YP_004605496.1| ribosomal large subunit pseudouridine synthase B [Corynebacterium resistens DSM 45100] gi|336101512|gb|AEI09332.1| ribosomal large subunit pseudouridine synthase B [Corynebacterium resistens DSM 45100] Length=275 Score = 313 bits (802), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 154/248 (63%), Positives = 193/248 (78%), Gaps = 0/248 (0%) Query 7 ESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGA 66 + +E + +RLQKVLS AG+ASRR +EK+I GRVEV+G VV ++G R+DP V VVRVDG Sbjct 28 DKKEKQQVRLQKVLSSAGVASRRMSEKLIAAGRVEVNGEVVQQMGLRIDPSVDVVRVDGT 87 Query 67 RVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLM 126 RV +++ +VY ALNKPRG+HSTM DD GRP +G+LIE K + LFHVGRLDA TEGL+ Sbjct 88 RVQVNEEMVYFALNKPRGVHSTMHDDLGRPHVGELIEAKFNQGQGLFHVGRLDAATEGLL 147 Query 127 LLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDA 186 LLTNDGELA+RLMHP +EV KTY+ATV G RGL RTL+ G++L+DG A D +VD Sbjct 148 LLTNDGELANRLMHPKYEVSKTYMATVLGEADRGLIRTLKDGVDLEDGMARADYVQIVDV 207 Query 187 IPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIG 246 GK+L++V LHEGR IVRR+L AAGFPV+ALVRT I V LG+Q+PG+VRAL +E+ Sbjct 208 WQGKSLIKVELHEGRKHIVRRMLKAAGFPVQALVRTKIHTVQLGEQKPGTVRALNRSELQ 267 Query 247 QLYQAVGL 254 LY+AVGL Sbjct 268 SLYKAVGL 275 >gi|25028115|ref|NP_738169.1| hypothetical protein CE1559 [Corynebacterium efficiens YS-314] gi|259507172|ref|ZP_05750072.1| RNA pseudouridine synthase [Corynebacterium efficiens YS-314] gi|23493399|dbj|BAC18369.1| conserved hypothetical protein [Corynebacterium efficiens YS-314] gi|259165253|gb|EEW49807.1| RNA pseudouridine synthase [Corynebacterium efficiens YS-314] Length=329 Score = 309 bits (791), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 151/242 (63%), Positives = 186/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVL+QAG+ASRR AE +I +GRVEV+G +VT GTRV+P V+RVDG R+ +++ Sbjct 88 GIRLQKVLAQAGVASRRHAEILIDNGRVEVNGRIVTTQGTRVNPNSDVIRVDGVRININE 147 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 L Y LNKPRGMHSTMSDD GRPC+GDL+ K ++LFHVGRLDADTEGL+LLTNDG Sbjct 148 DLEYFVLNKPRGMHSTMSDDLGRPCVGDLVSEKTASGQRLFHVGRLDADTEGLLLLTNDG 207 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G L TLR GIEL+DGPA D ++D GK+L Sbjct 208 ELANRLMHPKYEVRKTYLATVRGEAGPNLVTTLRKGIELEDGPAKADYVQIIDTFQGKSL 267 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ +HEGR IVRR+L AGFPVE LVRT + V LG+Q+PGS+RAL ++E+ LY+ V Sbjct 268 IRLEIHEGRKHIVRRMLDEAGFPVERLVRTKLHTVQLGEQKPGSLRALNASELASLYKVV 327 Query 253 GL 254 L Sbjct 328 EL 329 >gi|68535954|ref|YP_250659.1| putative pseudouridylate synthase [Corynebacterium jeikeium K411] gi|260578661|ref|ZP_05846569.1| RNA pseudouridylate synthase [Corynebacterium jeikeium ATCC 43734] gi|68263553|emb|CAI37041.1| putative pseudouridylate synthase [Corynebacterium jeikeium K411] gi|258603158|gb|EEW16427.1| RNA pseudouridylate synthase [Corynebacterium jeikeium ATCC 43734] Length=290 Score = 308 bits (790), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 150/253 (60%), Positives = 192/253 (76%), Gaps = 2/253 (0%) Query 2 MAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVV 61 + +PE E +RLQKVL+ AG+ASRR +EK+I GRVEV+G VV ++GTR+DP V +V Sbjct 40 LNKPES--EKAQVRLQKVLASAGVASRRMSEKLIAAGRVEVNGEVVVKMGTRIDPSVDIV 97 Query 62 RVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDAD 121 RVDG RV +++ +VY LNKPRG+HSTMSDD GRPC+GDL+ +++ + LFHVGRLDA Sbjct 98 RVDGERVQVNEEMVYFVLNKPRGVHSTMSDDLGRPCVGDLVGTRLKEGQGLFHVGRLDAQ 157 Query 122 TEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDF 181 TEGL+LLTNDGELA+RLMHP +EV KTY+ATV G R L R L+ G+ELDDG A D Sbjct 158 TEGLLLLTNDGELANRLMHPKYEVKKTYMATVLGEASRKLIRELKDGVELDDGIARADSV 217 Query 182 AVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR 241 +VD GK+L++V LHEGR IVRR+L AGFPV+ALVRT I V LG+Q+PG++RAL Sbjct 218 QIVDVWQGKSLIKVELHEGRKHIVRRMLKEAGFPVQALVRTKIHTVQLGEQKPGTIRALN 277 Query 242 SNEIGQLYQAVGL 254 E+ +Y+ VGL Sbjct 278 QAELQSMYKKVGL 290 >gi|226360073|ref|YP_002777851.1| pseudouridine synthase [Rhodococcus opacus B4] gi|226238558|dbj|BAH48906.1| pseudouridine synthase [Rhodococcus opacus B4] Length=350 Score = 308 bits (789), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 165/242 (69%), Positives = 197/242 (82%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRRAAE++I GRVEVDG +V E G R+DP+ AVVRVDG RVV+ Sbjct 109 GMRLQKVLAQAGVASRRAAEELISQGRVEVDGRIVIEQGLRIDPENAVVRVDGVRVVVQK 168 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 LV+LALNKPRG STMSDD GRPC+GD++ +V ++LFHVGRLDADTEGL+LLTNDG Sbjct 169 DLVHLALNKPRGWQSTMSDDLGRPCVGDIVSERVAAGQRLFHVGRLDADTEGLLLLTNDG 228 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 +LAHRLMHPS EV KTYLATV+G++ RG+G+ L+ G+ELDDGPA VD F ++D GK+L Sbjct 229 DLAHRLMHPSFEVSKTYLATVSGALERGVGKKLKEGVELDDGPAKVDTFTLLDINEGKSL 288 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRVTLHEGR IVRRL A G PV LVRTDIGAV+LG QRPG++R L E+G LY AV Sbjct 289 VRVTLHEGRKHIVRRLFDAVGHPVIRLVRTDIGAVALGDQRPGTLRVLGRGEVGGLYGAV 348 Query 253 GL 254 GL Sbjct 349 GL 350 >gi|111017942|ref|YP_700914.1| pseudouridylate synthase ribosomal large subunit [Rhodococcus jostii RHA1] gi|110817472|gb|ABG92756.1| pseudouridylate synthase ribosomal large subunit [Rhodococcus jostii RHA1] Length=241 Score = 307 bits (786), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 164/241 (69%), Positives = 196/241 (82%), Gaps = 0/241 (0%) Query 14 IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDS 73 +RLQKVL+QAG+ASRRAAE++I GRVEVDG +V E G R+DP+ AVVRVDG RVV+ Sbjct 1 MRLQKVLAQAGVASRRAAEELISQGRVEVDGRIVIEQGLRIDPENAVVRVDGVRVVVQKD 60 Query 74 LVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGE 133 LV+LALNKPRG STMSDD GRPC+GD++ +V ++LFHVGRLDADTEGL+LLTNDG+ Sbjct 61 LVHLALNKPRGWQSTMSDDLGRPCVGDIVSERVAAGQRLFHVGRLDADTEGLLLLTNDGD 120 Query 134 LAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLV 193 LAHRLMHPS EV KTYLATV+G++ RG+G+ L+ G+ELDDGPA VD F ++D GK+LV Sbjct 121 LAHRLMHPSFEVSKTYLATVSGALERGVGKKLKEGVELDDGPAKVDTFTLLDINEGKSLV 180 Query 194 RVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVG 253 RVTLHEGR IVRRL A G PV LVRTDIGAV+LG QRPG++R L E+G LY AVG Sbjct 181 RVTLHEGRKHIVRRLFDAVGHPVIRLVRTDIGAVALGDQRPGTLRVLGRGEVGGLYGAVG 240 Query 254 L 254 L Sbjct 241 L 241 >gi|213965939|ref|ZP_03394129.1| ribosomal large subunit pseudouridine synthase B [Corynebacterium amycolatum SK46] gi|213951353|gb|EEB62745.1| ribosomal large subunit pseudouridine synthase B [Corynebacterium amycolatum SK46] Length=324 Score = 306 bits (784), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 149/242 (62%), Positives = 185/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AEK+I +GRVEVDG +VT G RVDP +V+RVDG+RV++++ Sbjct 83 GVRLQKVLAQAGVASRRMAEKLIDEGRVEVDGKIVTRQGVRVDPNTSVIRVDGSRVIVNE 142 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+ STM DD GRPC+GD+I K+ ++LFHVGRLDA TEGL+LLTNDG Sbjct 143 DMQYFVLNKPRGVQSTMHDDMGRPCVGDIIGEKISAGQRLFHVGRLDAATEGLLLLTNDG 202 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHPS+EV KTY+ATV G V + R L GIELDDG A D ++D G+++ Sbjct 203 ELANRLMHPSYEVTKTYMATVVGEVDSKVMRELEKGIELDDGIAKADMAQIIDVWQGRSI 262 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VR+ LHEGR IVRR+L AGFPVE LVRT I V LG+Q PG++RAL E+ LY AV Sbjct 263 VRIELHEGRKHIVRRMLKTAGFPVERLVRTKIHTVQLGEQTPGALRALNRAELTSLYNAV 322 Query 253 GL 254 GL Sbjct 323 GL 324 >gi|331697591|ref|YP_004333830.1| pseudouridine synthase Rsu [Pseudonocardia dioxanivorans CB1190] gi|326952280|gb|AEA25977.1| pseudouridine synthase Rsu [Pseudonocardia dioxanivorans CB1190] Length=252 Score = 305 bits (782), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 155/245 (64%), Positives = 187/245 (77%), Gaps = 3/245 (1%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRRAAE++I GRV VDG +V E+G RVDP AVV VDG+R+VL D Sbjct 8 GVRLQKVLAQAGVASRRAAEELIAAGRVSVDGEIVREMGRRVDPDTAVVHVDGSRIVLRD 67 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERK---VRGTKKLFHVGRLDADTEGLMLLT 129 LVYLALNKPRGM STMSDDRGR C+GDL+ + + +LFHVGRLDADTEGL+LLT Sbjct 68 DLVYLALNKPRGMLSTMSDDRGRECVGDLVADRAELLNQAGRLFHVGRLDADTEGLLLLT 127 Query 130 NDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPG 189 NDGEL HRLMHPS EV KTY+A V G V R +G+ LR G+EL+DGP V F +VD+ G Sbjct 128 NDGELGHRLMHPSFEVQKTYVAEVAGQVARDVGKRLRTGVELEDGPVVVHSFRLVDSSGG 187 Query 190 KTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLY 249 +++V + LHEGR +VRRL+ G+PV LVRT IG V LG QRPG +R L E+G LY Sbjct 188 RSMVEIVLHEGRKHVVRRLMDEVGYPVLRLVRTAIGDVRLGDQRPGKLRPLNQAEVGALY 247 Query 250 QAVGL 254 +AVGL Sbjct 248 RAVGL 252 >gi|333919205|ref|YP_004492786.1| Pseudouridine synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333481426|gb|AEF39986.1| Pseudouridine synthase [Amycolicicoccus subflavus DQS3-9A1] Length=241 Score = 303 bits (777), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 151/241 (63%), Positives = 184/241 (77%), Gaps = 0/241 (0%) Query 14 IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDS 73 +RLQKVL+QAG+ASRR E+MI RVEV+G +VT G R+DP AVV+VDG RV++ + Sbjct 1 MRLQKVLAQAGVASRRVCEQMIDKRRVEVNGKIVTTQGMRIDPSTAVVKVDGMRVMITEE 60 Query 74 LVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGE 133 LV+LALNKPRG STM D+ GRPC+GDL+ ++ ++LFHVGRLDA+TEGL+LLTNDGE Sbjct 61 LVHLALNKPRGWQSTMLDELGRPCVGDLVAERIASGQRLFHVGRLDAETEGLLLLTNDGE 120 Query 134 LAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLV 193 LAHRLMHPS++V KTYLA V G V R + R L AG+ LDDGP VD F+VVDA TLV Sbjct 121 LAHRLMHPSYKVQKTYLADVEGVVRRSVDRALEAGVTLDDGPVRVDAFSVVDAFDKSTLV 180 Query 194 RVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVG 253 ++ LHEGR IVRRLL G PV LVRT IG+V LG QRPG++RAL E+G LY+ VG Sbjct 181 KIVLHEGRKHIVRRLLEHVGHPVTRLVRTQIGSVHLGDQRPGTIRALNRQEVGALYKEVG 240 Query 254 L 254 L Sbjct 241 L 241 >gi|305680918|ref|ZP_07403725.1| putative pseudouridine synthase B, ribosomal large subunit [Corynebacterium matruchotii ATCC 14266] gi|305659123|gb|EFM48623.1| putative pseudouridine synthase B, ribosomal large subunit [Corynebacterium matruchotii ATCC 14266] Length=285 Score = 303 bits (777), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 149/242 (62%), Positives = 186/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AE MI GRVEV+G VV + G RV+P+V V+RVDG RV +++ Sbjct 44 GVRLQKVLAQAGVASRRNAEIMIDSGRVEVNGAVVMQQGVRVNPKVDVIRVDGVRVNVNN 103 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+HSTMSDD GRPCIGDL+ ++ + LFHVGRLDADTEGL+LLTNDG Sbjct 104 NHQYFVLNKPRGIHSTMSDDLGRPCIGDLVSERISAGQGLFHVGRLDADTEGLILLTNDG 163 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RL HP +EV KTY+A V G R L TL+ G+ELDDGPA D +VD G++L Sbjct 164 ELANRLSHPKYEVSKTYIAEVLGEADRSLVTTLKNGVELDDGPAAADYVQIVDVHQGRSL 223 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 VRV LHEGR IVRR+L AAG+PV+ LVRT + V LG+Q+PG++RAL NE+ LY+AV Sbjct 224 VRVQLHEGRKHIVRRMLKAAGYPVQYLVRTKLHTVQLGEQKPGTIRALNDNELRSLYKAV 283 Query 253 GL 254 + Sbjct 284 EM 285 >gi|302528005|ref|ZP_07280347.1| pseudouridylate synthase ribosomal large subunit [Streptomyces sp. AA4] gi|302436900|gb|EFL08716.1| pseudouridylate synthase ribosomal large subunit [Streptomyces sp. AA4] Length=250 Score = 303 bits (776), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 155/247 (63%), Positives = 182/247 (74%), Gaps = 0/247 (0%) Query 8 SREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGAR 67 + P GIRLQKVLSQAG+ASRRAAE +I GRVEVDG VVTELG RV P AV+ VDG R Sbjct 4 EQHPDGIRLQKVLSQAGVASRRAAEDLIAAGRVEVDGEVVTELGRRVHPDEAVIHVDGTR 63 Query 68 VVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLML 127 V L D LVYLA NKP+G+HSTMSDDRGRPC+GD + + T + HVGRLD +TEGL+L Sbjct 64 VNLRDDLVYLAFNKPKGVHSTMSDDRGRPCVGDYLRGRWEETPGVVHVGRLDENTEGLLL 123 Query 128 LTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAI 187 LTNDG+L HRLMHPS+ V KTY A V G VPRGLG+ LRAG EL DG VD F V D Sbjct 124 LTNDGDLGHRLMHPSYRVLKTYFAEVEGLVPRGLGKELRAGWELPDGIVKVDQFRVKDMH 183 Query 188 PGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQ 247 G++++ + +HEGR IVRRL+AA G PV LVRT +G V LG QR G++R L E+G Sbjct 184 SGRSMIELVIHEGRKHIVRRLMAATGHPVRKLVRTAVGDVQLGNQRQGTIRRLNRGEVGA 243 Query 248 LYQAVGL 254 LY+ VGL Sbjct 244 LYRTVGL 250 >gi|300787858|ref|YP_003768149.1| ribosomal large subunit pseudouridine synthase B [Amycolatopsis mediterranei U32] gi|299797372|gb|ADJ47747.1| ribosomal large subunit pseudouridine synthase B [Amycolatopsis mediterranei U32] gi|340529430|gb|AEK44635.1| ribosomal large subunit pseudouridine synthase B [Amycolatopsis mediterranei S699] Length=250 Score = 303 bits (775), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 157/247 (64%), Positives = 182/247 (74%), Gaps = 0/247 (0%) Query 8 SREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGAR 67 S P G+RLQKVLSQAG+ASRRAAE +IV GRVEVDG VVTELG RVDP A++ VDG R Sbjct 4 SEHPDGVRLQKVLSQAGVASRRAAEDLIVAGRVEVDGEVVTELGRRVDPDAAIIHVDGTR 63 Query 68 VVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLML 127 V L D L+YLALNKP+G+HSTMSDDRGRPC+GD + + T + HVGRLD +TEGL+L Sbjct 64 VNLRDDLIYLALNKPKGVHSTMSDDRGRPCVGDYLRGRYEETPGVVHVGRLDENTEGLLL 123 Query 128 LTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAI 187 LTNDG+L HRLMHPS+ V KTYLA V G VPRGLG+ LR G EL DG VD F V D Sbjct 124 LTNDGDLGHRLMHPSYRVLKTYLAEVDGLVPRGLGKELRNGWELPDGIVKVDQFRVKDMH 183 Query 188 PGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQ 247 GK+LV + +HEG+ IVRRLL G PV LVRT +G V LG QR GS+R L E+G Sbjct 184 SGKSLVELVIHEGKKHIVRRLLKDTGHPVLKLVRTAVGDVQLGNQRVGSIRRLTKTEVGA 243 Query 248 LYQAVGL 254 LY+ V L Sbjct 244 LYRNVEL 250 >gi|38233785|ref|NP_939552.1| putative pseudouridine synthase B [Corynebacterium diphtheriae NCTC 13129] gi|38200046|emb|CAE49722.1| Putative pseudouridine synthase B [Corynebacterium diphtheriae] Length=321 Score = 302 bits (773), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 147/242 (61%), Positives = 186/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVL+QAG+ASRR AE +I GRVEV+G +V G RV+P V V+RVDG RV +++ Sbjct 80 GIRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMRVNPNVDVIRVDGVRVNVNE 139 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 +L Y LNKPRG+ STMSDD GRPC+GD++ ++ ++LFHVGRLDA TEGL+LLTNDG Sbjct 140 NLQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERISAGQRLFHVGRLDAATEGLLLLTNDG 199 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G + L + LR GIELDDGPA D ++D GK+L Sbjct 200 ELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDDGPAKADLVQIIDTFQGKSL 259 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ LHEGR IVRR+L AGFPV+ LVRT I + LG+Q PG++RAL S+E+ LY+AV Sbjct 260 IRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQTPGAIRALNSSELASLYKAV 319 Query 253 GL 254 G+ Sbjct 320 GM 321 >gi|225021516|ref|ZP_03710708.1| hypothetical protein CORMATOL_01537 [Corynebacterium matruchotii ATCC 33806] gi|224945898|gb|EEG27107.1| hypothetical protein CORMATOL_01537 [Corynebacterium matruchotii ATCC 33806] Length=241 Score = 301 bits (772), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 148/239 (62%), Positives = 184/239 (77%), Gaps = 0/239 (0%) Query 14 IRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDS 73 +RLQKVL+QAG+ASRR AE MI GRVEV+G VV + G RV+P+V V+RVDG RV ++++ Sbjct 1 MRLQKVLAQAGVASRRNAEIMIDSGRVEVNGAVVMQQGVRVNPEVDVIRVDGVRVNVNNN 60 Query 74 LVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGE 133 Y LNKPRG+HSTMSDD GRPCIGDL+ ++ + LFHVGRLDADTEGL+LLTNDGE Sbjct 61 HQYFVLNKPRGIHSTMSDDLGRPCIGDLVSERISAGQGLFHVGRLDADTEGLILLTNDGE 120 Query 134 LAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLV 193 LA+RL HP +EV KTY+A V G R L TL+ G+ELDDGPA D +VD G++LV Sbjct 121 LANRLSHPKYEVSKTYIAEVLGEADRSLVTTLKNGVELDDGPAAADYVQIVDVHQGRSLV 180 Query 194 RVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 RV LHEGR IVRR+L AAG+PV+ LVRT + V LG+Q+PG++RAL NE+ LY+AV Sbjct 181 RVQLHEGRKHIVRRMLKAAGYPVQYLVRTKLHTVQLGEQKPGTIRALNDNELRSLYKAV 239 >gi|220912302|ref|YP_002487611.1| pseudouridine synthase [Arthrobacter chlorophenolicus A6] gi|219859180|gb|ACL39522.1| pseudouridine synthase [Arthrobacter chlorophenolicus A6] Length=403 Score = 301 bits (772), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 144/242 (60%), Positives = 181/242 (75%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKV++ AG+ASRR E+MI +GRVEVDG VVTELG R+DP AV+ VDG R+ LD+ Sbjct 162 GVRLQKVMASAGVASRRVCEEMIAEGRVEVDGQVVTELGVRIDPATAVIHVDGLRIQLDE 221 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 +LVY+ NKP+G+ STM D GRPCI D ++ ++LFHVGRLD TEGL+LLTNDG Sbjct 222 NLVYMVFNKPKGVVSTMEDPDGRPCISDFLKNNKNTGERLFHVGRLDVATEGLLLLTNDG 281 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RL HPS+EVPKTYL V G P+G+G L+AG+EL+DGPA VD F +VD+ PG L Sbjct 282 ELANRLTHPSYEVPKTYLVQVRGPFPQGIGAQLKAGVELEDGPAAVDSFRLVDSTPGHVL 341 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 + V LH G+NRIVRR+ A GFPV+ LVR +G + LG QR GS+R L E+G L +V Sbjct 342 IEVVLHSGKNRIVRRMFDAVGFPVQRLVRVKVGPIGLGDQRQGSIRNLGKQEVGHLLASV 401 Query 253 GL 254 GL Sbjct 402 GL 403 >gi|302330665|gb|ADL20859.1| RNA pseudouridine synthase B [Corynebacterium pseudotuberculosis 1002] gi|308276349|gb|ADO26248.1| 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase [Corynebacterium pseudotuberculosis I19] Length=286 Score = 301 bits (771), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 146/242 (61%), Positives = 185/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVL+QAG+ASRR AE +I GR+EV+G +V G RV+P ++RVDG R+ +++ Sbjct 45 GIRLQKVLAQAGVASRRHAEILIDAGRIEVNGKIVLTQGVRVNPHADIIRVDGVRINVNE 104 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+ STMSDD GRPC+GD++ ++ ++LFHVGRLDA TEGL+LLTNDG Sbjct 105 DMQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERIAAGQRLFHVGRLDAATEGLLLLTNDG 164 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G + L + LR GIELDDGPA D +VDA GK+L Sbjct 165 ELANRLMHPKYEVTKTYLATVLGEADKRLIKQLRDGIELDDGPAKADFVQIVDAHQGKSL 224 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ LHEGR IVRR+L AGFPVE LVRT I + LG+Q PG+VRAL S+E+ LY+AV Sbjct 225 IRIELHEGRKHIVRRMLKTAGFPVERLVRTKIHTIQLGEQTPGAVRALNSSELASLYKAV 284 Query 253 GL 254 G+ Sbjct 285 GM 286 >gi|300858398|ref|YP_003783381.1| hypothetical protein cpfrc_00980 [Corynebacterium pseudotuberculosis FRC41] gi|300685852|gb|ADK28774.1| hypothetical protein cpfrc_00980 [Corynebacterium pseudotuberculosis FRC41] gi|302206111|gb|ADL10453.1| RNA pseudouridine synthase B [Corynebacterium pseudotuberculosis C231] gi|341824785|gb|AEK92306.1| RNA pseudouridine synthase B [Corynebacterium pseudotuberculosis PAT10] Length=373 Score = 301 bits (770), Expect = 8e-80, Method: Compositional matrix adjust. Identities = 146/242 (61%), Positives = 185/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 GIRLQKVL+QAG+ASRR AE +I GR+EV+G +V G RV+P ++RVDG R+ +++ Sbjct 132 GIRLQKVLAQAGVASRRHAEILIDAGRIEVNGKIVLTQGVRVNPHADIIRVDGVRINVNE 191 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+ STMSDD GRPC+GD++ ++ ++LFHVGRLDA TEGL+LLTNDG Sbjct 192 DMQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERIAAGQRLFHVGRLDAATEGLLLLTNDG 251 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G + L + LR GIELDDGPA D +VDA GK+L Sbjct 252 ELANRLMHPKYEVTKTYLATVLGEADKRLIKQLRDGIELDDGPAKADFVQIVDAHQGKSL 311 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ LHEGR IVRR+L AGFPVE LVRT I + LG+Q PG+VRAL S+E+ LY+AV Sbjct 312 IRIELHEGRKHIVRRMLKTAGFPVERLVRTKIHTIQLGEQTPGAVRALNSSELASLYKAV 371 Query 253 GL 254 G+ Sbjct 372 GM 373 >gi|226306743|ref|YP_002766703.1| pseudouridine synthase [Rhodococcus erythropolis PR4] gi|226185860|dbj|BAH33964.1| putative pseudouridine synthase [Rhodococcus erythropolis PR4] Length=267 Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 161/242 (67%), Positives = 192/242 (80%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRRAAE++I GRVEVDG +V E G RVDP+ AVVRVDG RVV+ Sbjct 26 GVRLQKVLAQAGVASRRAAEELIDQGRVEVDGRIVVEQGLRVDPENAVVRVDGVRVVVQK 85 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 LVYLA+NKPRG TMSDD GRPC+GD++ +V+ ++LFHVGRLDADTEGL+L TNDG Sbjct 86 DLVYLAMNKPRGWQCTMSDDLGRPCVGDIVSERVQSGQRLFHVGRLDADTEGLLLFTNDG 145 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 +LAHRLMHPS EVPKTYLATV G V R G+ LR G+ LDDGPA VD F V++ GKTL Sbjct 146 DLAHRLMHPSFEVPKTYLATVHGVVERSTGKQLRDGVTLDDGPAKVDAFTVLEINEGKTL 205 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 V++ LHEGR IVRRLL A G PV LVRT++G V+LG QRPG+ R L +E+G LY+AV Sbjct 206 VKLVLHEGRKHIVRRLLDAVGHPVVRLVRTNVGVVALGDQRPGTQRVLGRSEVGGLYEAV 265 Query 253 GL 254 GL Sbjct 266 GL 267 >gi|257056522|ref|YP_003134354.1| ribosomal large subunit pseudouridine synthase B [Saccharomonospora viridis DSM 43017] gi|256586394|gb|ACU97527.1| ribosomal large subunit pseudouridine synthase B [Saccharomonospora viridis DSM 43017] Length=247 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 153/241 (64%), Positives = 184/241 (77%), Gaps = 3/241 (1%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL++AG+ASRRA+E++I GRV VDG VV ELG RVDP AV+ VDG RV + D Sbjct 9 GVRLQKVLAKAGVASRRASEELIAAGRVSVDGVVVRELGRRVDPDTAVIHVDGIRVQVRD 68 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 LVYLALNKPRG+HSTMSD +GRPC+GD + + ++LFHVGRLDADTEGL+LLTNDG Sbjct 69 DLVYLALNKPRGVHSTMSDAQGRPCVGDYVADR---PERLFHVGRLDADTEGLLLLTNDG 125 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 +LAH+LMHPS V KTYLA V G+V RGLG+ LRAG++L DGP D F + D P ++L Sbjct 126 DLAHKLMHPSFHVTKTYLAEVEGAVARGLGKRLRAGVQLSDGPVTADAFRIKDVRPNRSL 185 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 V + LHEGR IVRRLLA G PV LVRT IG V LG +PG++R L EIG LY+AV Sbjct 186 VEIVLHEGRKHIVRRLLAEVGHPVRKLVRTAIGEVRLGTTKPGTLRTLTQQEIGLLYRAV 245 Query 253 G 253 G Sbjct 246 G 246 >gi|334696769|gb|AEG81566.1| hypothetical protein CULC809_01033 [Corynebacterium ulcerans 809] Length=373 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 145/242 (60%), Positives = 184/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AE +I GRVEV+G +V G RV+P ++RVDG R+ +++ Sbjct 132 GVRLQKVLAQAGVASRRHAEILIDSGRVEVNGKIVLTQGVRVNPNADIIRVDGVRINVNE 191 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+ STMSDD GRPC+GD++ ++ ++LFHVGRLDA TEGL+LLTNDG Sbjct 192 DMQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERIAAGQRLFHVGRLDAATEGLLLLTNDG 251 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G + L + LR GIELDDGPA D +VD GK+L Sbjct 252 ELANRLMHPKYEVAKTYLATVLGEADKRLVKQLRDGIELDDGPAKADFVQIVDTHQGKSL 311 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ LHEGR IVRR+L AGFPVE LVRT I + LG+Q PG+VRAL S+E+ LY+AV Sbjct 312 IRIELHEGRKHIVRRMLKTAGFPVERLVRTKIHTIQLGEQTPGAVRALNSSELASLYKAV 371 Query 253 GL 254 G+ Sbjct 372 GM 373 >gi|262182363|ref|ZP_06041784.1| putative pseudouridylate synthase [Corynebacterium aurimucosum ATCC 700975] Length=286 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 148/249 (60%), Positives = 188/249 (76%), Gaps = 0/249 (0%) Query 6 EESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDG 65 +++ + +G RLQKVL++AG+ASRR AE +I +GRVEV+G V+ + GTRVDP V+RVDG Sbjct 38 KKNSQNQGERLQKVLAKAGVASRRHAEILIDEGRVEVNGQVIIKQGTRVDPNKDVIRVDG 97 Query 66 ARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGL 125 R+ +++ Y LNKPRGM STMSDD GRPC+GD++ +V ++LFHVGRLDADTEGL Sbjct 98 TRINVNEETQYFVLNKPRGMQSTMSDDMGRPCVGDVVADRVVAGQRLFHVGRLDADTEGL 157 Query 126 MLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVD 185 +LLTNDGELA+RLMHP +EV KTYLATV G + L R LR GIEL+DG A D +VD Sbjct 158 LLLTNDGELANRLMHPKYEVTKTYLATVLGEADKKLIRQLREGIELEDGLAQADYVQIVD 217 Query 186 AIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEI 245 G +LVRV LHEGR IVRR+L AG+PV+ LVRT + V LG +PGS+RAL SNE+ Sbjct 218 KNQGYSLVRVELHEGRKHIVRRMLKEAGYPVQRLVRTKLHTVQLGDMKPGSLRALNSNEL 277 Query 246 GQLYQAVGL 254 LY+AVG+ Sbjct 278 TSLYKAVGM 286 >gi|337290656|ref|YP_004629677.1| hypothetical protein CULC22_01048 [Corynebacterium ulcerans BR-AD22] gi|334698962|gb|AEG83758.1| hypothetical protein CULC22_01048 [Corynebacterium ulcerans BR-AD22] Length=373 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 145/242 (60%), Positives = 184/242 (77%), Gaps = 0/242 (0%) Query 13 GIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDD 72 G+RLQKVL+QAG+ASRR AE +I GRVEV+G +V G RV+P ++RVDG R+ +++ Sbjct 132 GVRLQKVLAQAGVASRRHAEILIDSGRVEVNGKIVLTQGVRVNPNADIIRVDGVRINVNE 191 Query 73 SLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDG 132 + Y LNKPRG+ STMSDD GRPC+GD++ ++ ++LFHVGRLDA TEGL+LLTNDG Sbjct 192 DMQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERIAAGQRLFHVGRLDAATEGLLLLTNDG 251 Query 133 ELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTL 192 ELA+RLMHP +EV KTYLATV G + L + LR GIELDDGPA D +VD GK+L Sbjct 252 ELANRLMHPKYEVAKTYLATVLGEADKRLVKQLRDGIELDDGPAKADFVQIVDTHQGKSL 311 Query 193 VRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAV 252 +R+ LHEGR IVRR+L AGFPVE LVRT I + LG+Q PG+VRAL S+E+ LY+AV Sbjct 312 IRIELHEGRKHIVRRMLKTAGFPVERLVRTKIHTIQLGEQTPGAVRALNSSELASLYKAV 371 Query 253 GL 254 G+ Sbjct 372 GM 373 >gi|227833146|ref|YP_002834853.1| putative pseudouridylate synthase [Corynebacterium aurimucosum ATCC 700975] gi|227454162|gb|ACP32915.1| putative pseudouridylate synthase [Corynebacterium aurimucosum ATCC 700975] Length=305 Score = 299 bits (765), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 148/249 (60%), Positives = 188/249 (76%), Gaps = 0/249 (0%) Query 6 EESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDG 65 +++ + +G RLQKVL++AG+ASRR AE +I +GRVEV+G V+ + GTRVDP V+RVDG Sbjct 57 KKNSQNQGERLQKVLAKAGVASRRHAEILIDEGRVEVNGQVIIKQGTRVDPNKDVIRVDG 116 Query 66 ARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGL 125 R+ +++ Y LNKPRGM STMSDD GRPC+GD++ +V ++LFHVGRLDADTEGL Sbjct 117 TRINVNEETQYFVLNKPRGMQSTMSDDMGRPCVGDVVADRVVAGQRLFHVGRLDADTEGL 176 Query 126 MLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVD 185 +LLTNDGELA+RLMHP +EV KTYLATV G + L R LR GIEL+DG A D +VD Sbjct 177 LLLTNDGELANRLMHPKYEVTKTYLATVLGEADKKLIRQLREGIELEDGLAQADYVQIVD 236 Query 186 AIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEI 245 G +LVRV LHEGR IVRR+L AG+PV+ LVRT + V LG +PGS+RAL SNE+ Sbjct 237 KNQGYSLVRVELHEGRKHIVRRMLKEAGYPVQRLVRTKLHTVQLGDMKPGSLRALNSNEL 296 Query 246 GQLYQAVGL 254 LY+AVG+ Sbjct 297 TSLYKAVGM 305 Lambda K H 0.320 0.139 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 371539772520 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40