BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1734c

Length=80
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608872|ref|NP_216250.1|  hypothetical protein Rv1734c [Mycob...   164    5e-39
gi|340626739|ref|YP_004745191.1|  hypothetical protein MCAN_17451...   163    1e-38
gi|31792922|ref|NP_855415.1|  hypothetical protein Mb1763c [Mycob...   162    2e-38
gi|183983474|ref|YP_001851765.1|  pyruvate dehydrogenase (E2 comp...   115    3e-24
gi|120402421|ref|YP_952250.1|  branched-chain alpha-keto acid deh...   113    8e-24
gi|296169081|ref|ZP_06850741.1|  possible dihydrolipoyllysine-res...   113    1e-23
gi|240171836|ref|ZP_04750495.1|  branched-chain alpha-keto acid d...   112    1e-23
gi|108798065|ref|YP_638262.1|  branched-chain alpha-keto acid deh...   102    1e-20
gi|186471765|ref|YP_001863083.1|  dehydrogenase catalytic domain-...  85.9    2e-15
gi|167615708|ref|ZP_02384343.1|  branched-chain alpha-keto acid d...  84.7    4e-15
gi|167577555|ref|ZP_02370429.1|  branched-chain alpha-keto acid d...  84.3    5e-15
gi|91786666|ref|YP_547618.1|  branched-chain alpha-keto acid dehy...  83.6    8e-15
gi|187926814|ref|YP_001893159.1|  catalytic domain of components ...  81.6    3e-14
gi|83716054|ref|YP_439127.1|  branched-chain alpha-keto acid dehy...  81.6    3e-14
gi|320353605|ref|YP_004194944.1|  dihydrolipoyllysine-residue ace...  80.9    7e-14
gi|217969836|ref|YP_002355070.1|  branched-chain alpha-keto acid ...  80.5    8e-14
gi|89899199|ref|YP_521670.1|  branched-chain alpha-keto acid dehy...  80.1    1e-13
gi|224824123|ref|ZP_03697231.1|  catalytic domain of component of...  79.3    1e-13
gi|254380641|ref|ZP_04996007.1|  conserved hypothetical protein [...  79.3    2e-13
gi|302039130|ref|YP_003799452.1|  putative pyruvate dehydrogenase...  78.6    3e-13
gi|51245946|ref|YP_065830.1|  branched-chain alpha-keto acid dehy...  77.4    7e-13
gi|116669074|ref|YP_830007.1|  dehydrogenase catalytic domain-con...  76.3    1e-12
gi|325961516|ref|YP_004239422.1|  pyruvate/2-oxoglutarate dehydro...  75.5    3e-12
gi|119947205|ref|YP_944885.1|  pyruvate dehydrogenase complex, E2...  75.1    3e-12
gi|51247011|ref|YP_066894.1|  branched-chain alpha-keto acid dehy...  73.6    1e-11
gi|148263674|ref|YP_001230380.1|  branched-chain alpha-keto acid ...  72.8    2e-11
gi|291300947|ref|YP_003512225.1|  Dihydrolipoyllysine-residue(2-m...  72.8    2e-11
gi|328542713|ref|YP_004302822.1|  pyruvate dehydrogenase, E2 comp...  70.9    5e-11
gi|323138355|ref|ZP_08073426.1|  Dihydrolipoyllysine-residue acet...  67.0    9e-10
gi|152992561|ref|YP_001358282.1|  pyruvate/2-oxoglutarate dehydro...  63.9    7e-09
gi|307720480|ref|YP_003891620.1|  hypothetical protein Saut_0559 ...  60.5    8e-08
gi|134098967|ref|YP_001104628.1|  pyruvate dehydrogenase, E2 comp...  59.7    1e-07
gi|157375314|ref|YP_001473914.1|  dehydrogenase catalytic domain-...  56.2    2e-06
gi|114321742|ref|YP_743425.1|  dehydrogenase catalytic domain-con...  53.1    1e-05
gi|206900930|ref|YP_002250186.1|  dihydrolipoyllysine-residue ace...  52.0    3e-05
gi|298241072|ref|ZP_06964879.1|  Dihydrolipoyllysine-residue acet...  49.7    1e-04
gi|90423992|ref|YP_532362.1|  branched-chain alpha-keto acid dehy...  47.0    0.001
gi|298506473|gb|ADI85196.1|  pyruvate dehydrogenase complex, E2 p...  46.2    0.002
gi|254480044|ref|ZP_05093292.1|  2-oxo acid dehydrogenases acyltr...  46.2    0.002
gi|39997530|ref|NP_953481.1|  branched-chain alpha-keto acid dehy...  46.2    0.002
gi|62185091|ref|YP_219876.1|  branched-chain alpha-keto acid dehy...  45.8    0.002
gi|333410240|gb|EGK69227.1|  dihydrolipoamide acetyltransferase [...  45.8    0.002
gi|338533851|ref|YP_004667185.1|  pyruvate dehydrogenase complex,...  45.8    0.002
gi|344925094|ref|ZP_08778555.1|  branched-chain alpha-keto acid d...  45.8    0.002
gi|163793251|ref|ZP_02187227.1|  Pyruvate/2-oxoglutarate dehydrog...  45.4    0.002
gi|334693284|gb|AEG86502.1|  branched-chain alpha-keto acid dehyd...  45.4    0.003
gi|15618226|ref|NP_224511.1|  branched-chain alpha-keto acid dehy...  45.4    0.003
gi|329942827|ref|ZP_08291606.1|  pyruvate dehydrogenase complex d...  45.4    0.003
gi|119900159|ref|YP_935372.1|  hypothetical protein azo3870 [Azoa...  45.4    0.003
gi|108759682|ref|YP_630887.1|  pyruvate dehydrogenase complex, E2...  44.7    0.005


>gi|15608872|ref|NP_216250.1| hypothetical protein Rv1734c [Mycobacterium tuberculosis H37Rv]
 gi|121637642|ref|YP_977865.1| hypothetical protein BCG_1773c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|148661532|ref|YP_001283055.1| hypothetical protein MRA_1744 [Mycobacterium tuberculosis H37Ra]
 50 more sequence titles
 Length=80

 Score =  164 bits (414),  Expect = 5e-39, Method: Compositional matrix adjust.
 Identities = 80/80 (100%), Positives = 80/80 (100%), Gaps = 0/80 (0%)

Query  1   MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
           MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH
Sbjct  1   MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60

Query  61  RGALFFLSINELTRCAAVTG  80
           RGALFFLSINELTRCAAVTG
Sbjct  61  RGALFFLSINELTRCAAVTG  80


>gi|340626739|ref|YP_004745191.1| hypothetical protein MCAN_17451 [Mycobacterium canettii CIPT 
140010059]
 gi|340004929|emb|CCC44077.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=80

 Score =  163 bits (412),  Expect = 1e-38, Method: Compositional matrix adjust.
 Identities = 79/80 (99%), Positives = 80/80 (100%), Gaps = 0/80 (0%)

Query  1   MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
           MTNVGDQGVDAVFGVIYPPQVAL+SFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH
Sbjct  1   MTNVGDQGVDAVFGVIYPPQVALLSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60

Query  61  RGALFFLSINELTRCAAVTG  80
           RGALFFLSINELTRCAAVTG
Sbjct  61  RGALFFLSINELTRCAAVTG  80


>gi|31792922|ref|NP_855415.1| hypothetical protein Mb1763c [Mycobacterium bovis AF2122/97]
 gi|31618513|emb|CAD94465.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]
Length=80

 Score =  162 bits (409),  Expect = 2e-38, Method: Compositional matrix adjust.
 Identities = 79/80 (99%), Positives = 79/80 (99%), Gaps = 0/80 (0%)

Query  1   MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
           MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH
Sbjct  1   MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60

Query  61  RGALFFLSINELTRCAAVTG  80
           RGALFFLSINELTRCAAV G
Sbjct  61  RGALFFLSINELTRCAAVAG  80


>gi|183983474|ref|YP_001851765.1| pyruvate dehydrogenase (E2 component) [Mycobacterium marinum 
M]
 gi|183176800|gb|ACC41910.1| pyruvate dehydrogenase (E2 component) [Mycobacterium marinum 
M]
Length=413

 Score =  115 bits (287),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 53/72 (74%), Positives = 59/72 (82%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGVD VFGVIYPPQVA+V FGKPAQRVC +DG I V+TTV  TL ADH  SD H
Sbjct  333  VTNLGDQGVDTVFGVIYPPQVAIVGFGKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGH  392

Query  61   RGALFFLSINEL  72
            RGALF  +INEL
Sbjct  393  RGALFLAAINEL  404


>gi|120402421|ref|YP_952250.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Mycobacterium 
vanbaalenii PYR-1]
 gi|119955239|gb|ABM12244.1| catalytic domain of components of various dehydrogenase complexes 
[Mycobacterium vanbaalenii PYR-1]
Length=447

 Score =  113 bits (283),  Expect = 8e-24, Method: Compositional matrix adjust.
 Identities = 52/72 (73%), Positives = 60/72 (84%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGVD VFG+IYPPQVALV FGKPAQRVCAVDG I + TTV ATL ADH  SD H
Sbjct  367  VTNLGDQGVDTVFGIIYPPQVALVGFGKPAQRVCAVDGGIRIATTVHATLAADHRASDGH  426

Query  61   RGALFFLSINEL  72
            RGA+F  +I++L
Sbjct  427  RGAMFLAAIDQL  438


>gi|296169081|ref|ZP_06850741.1| possible dihydrolipoyllysine-residue acetyltransferase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295896272|gb|EFG75933.1| possible dihydrolipoyllysine-residue acetyltransferase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=292

 Score =  113 bits (282),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 52/72 (73%), Positives = 60/72 (84%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGVDAVFGVIYPPQVA+V FG+PA+RVC +DG I V+TTV  TL ADH  SD H
Sbjct  212  VTNLGDQGVDAVFGVIYPPQVAIVGFGQPAERVCVIDGGIRVVTTVQGTLAADHRASDGH  271

Query  61   RGALFFLSINEL  72
            RGALF  +INEL
Sbjct  272  RGALFLAAINEL  283


>gi|240171836|ref|ZP_04750495.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Mycobacterium 
kansasii ATCC 12478]
Length=294

 Score =  112 bits (281),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 52/72 (73%), Positives = 59/72 (82%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGVD VFGVIYPPQVA+V FGKP+QRVC +DG I V+TTV  TL ADH  SD H
Sbjct  214  VTNLGDQGVDTVFGVIYPPQVAIVGFGKPSQRVCVIDGGIRVVTTVQGTLAADHRASDGH  273

Query  61   RGALFFLSINEL  72
            RGALF  +INEL
Sbjct  274  RGALFLSAINEL  285


>gi|108798065|ref|YP_638262.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Mycobacterium 
sp. MCS]
 gi|119867161|ref|YP_937113.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Mycobacterium 
sp. KMS]
 gi|126433726|ref|YP_001069417.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Mycobacterium 
sp. JLS]
 gi|108768484|gb|ABG07206.1| catalytic domain of components of various dehydrogenase complexes 
[Mycobacterium sp. MCS]
 gi|119693250|gb|ABL90323.1| catalytic domain of components of various dehydrogenase complexes 
[Mycobacterium sp. KMS]
 gi|126233526|gb|ABN96926.1| catalytic domain of components of various dehydrogenase complexes 
[Mycobacterium sp. JLS]
Length=399

 Score =  102 bits (255),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 52/72 (73%), Positives = 58/72 (81%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGVD VFGVIYPPQVALV FGKP QRVCAVDG I + T + ATL ADH  SD H
Sbjct  319  ITNLGDQGVDTVFGVIYPPQVALVGFGKPVQRVCAVDGGIRIATALTATLAADHRASDGH  378

Query  61   RGALFFLSINEL  72
            RGALF  +INE+
Sbjct  379  RGALFLAAINEI  390


>gi|186471765|ref|YP_001863083.1| dehydrogenase catalytic domain-containing protein [Burkholderia 
phymatum STM815]
 gi|184198074|gb|ACC76037.1| catalytic domain of components of various dehydrogenase complexes 
[Burkholderia phymatum STM815]
Length=382

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Composition-based stats.
 Identities = 41/71 (58%), Positives = 52/71 (74%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQG   VFGVIYPPQVALV FG+  +R  A +G + ++ TV ATL ADH  SD H
Sbjct  302  VTNLGDQGTCEVFGVIYPPQVALVGFGRVIERPWAHNGEVTILPTVTATLSADHRVSDGH  361

Query  61   RGALFFLSINE  71
            RGALF L +++
Sbjct  362  RGALFLLELSD  372


>gi|167615708|ref|ZP_02384343.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Burkholderia 
thailandensis Bt4]
Length=283

 Score = 84.7 bits (208),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 39/71 (55%), Positives = 51/71 (72%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD+G   VFG+IYPPQVALV FG+  +R  A  GA+ VM  V A++ ADH  SD H
Sbjct  203  VTNLGDRGAAEVFGIIYPPQVALVGFGRIVERPWAEGGALGVMPVVTASVSADHRVSDGH  262

Query  61   RGALFFLSINE  71
            RGALF + ++E
Sbjct  263  RGALFLVELSE  273


>gi|167577555|ref|ZP_02370429.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Burkholderia 
thailandensis TXDOH]
Length=263

 Score = 84.3 bits (207),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 39/71 (55%), Positives = 51/71 (72%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD+G   VFG+IYPPQVALV FG+  +R  A  GA+ VM  V A++ ADH  SD H
Sbjct  183  VTNLGDRGAAEVFGIIYPPQVALVGFGRIVERPWAEGGALGVMPVVTASVSADHRVSDGH  242

Query  61   RGALFFLSINE  71
            RGALF + ++E
Sbjct  243  RGALFLVELSE  253


>gi|91786666|ref|YP_547618.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Polaromonas 
sp. JS666]
 gi|91695891|gb|ABE42720.1| catalytic domain of components of various dehydrogenase complexes 
[Polaromonas sp. JS666]
Length=420

 Score = 83.6 bits (205),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 40/72 (56%), Positives = 50/72 (70%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGV+AVFGVIYPPQVALV FG+ A      +G +  +  V ATL ADH  SD H
Sbjct  324  ITNLGDQGVEAVFGVIYPPQVALVGFGRVADGPWVEEGEVRALPLVTATLAADHRVSDGH  383

Query  61   RGALFFLSINEL  72
            +GALF   + +L
Sbjct  384  QGALFLAELRDL  395


>gi|187926814|ref|YP_001893159.1| catalytic domain of components of various dehydrogenase complexes 
[Ralstonia pickettii 12J]
 gi|241665144|ref|YP_002983503.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Ralstonia 
pickettii 12D]
 gi|187728568|gb|ACD29732.1| catalytic domain of components of various dehydrogenase complexes 
[Ralstonia pickettii 12J]
 gi|240867171|gb|ACS64831.1| catalytic domain of components of various dehydrogenase complexes 
[Ralstonia pickettii 12D]
Length=375

 Score = 81.6 bits (200),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 38/71 (54%), Positives = 50/71 (71%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGV  VFG+IYPPQVALV FG+ A++  A  G + +M  V A+L ADH  SD H
Sbjct  295  VTNLGDQGVAQVFGIIYPPQVALVGFGRIAEQPWAEAGGLKIMPAVTASLSADHRVSDGH  354

Query  61   RGALFFLSINE  71
            RGA F   +++
Sbjct  355  RGARFLSELSD  365


>gi|83716054|ref|YP_439127.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Burkholderia 
thailandensis E264]
 gi|257142239|ref|ZP_05590501.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Burkholderia 
thailandensis E264]
 gi|83649879|gb|ABC33943.1| probable pyruvate dehydrogenase, E2 component, dihydrolipoamide 
acetyltransferase [Burkholderia thailandensis E264]
Length=379

 Score = 81.6 bits (200),  Expect = 3e-14, Method: Composition-based stats.
 Identities = 39/71 (55%), Positives = 51/71 (72%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD+G   VFG+IYPPQVALV FG+  +R  A  GA+ VM  V A++ ADH  SD H
Sbjct  299  VTNLGDRGAAEVFGIIYPPQVALVGFGRIVERPWAEGGALGVMPVVTASVSADHRVSDGH  358

Query  61   RGALFFLSINE  71
            RGALF + ++E
Sbjct  359  RGALFLVELSE  369


>gi|320353605|ref|YP_004194944.1| dihydrolipoyllysine-residue acetyltransferase [Desulfobulbus 
propionicus DSM 2032]
 gi|320122107|gb|ADW17653.1| Dihydrolipoyllysine-residue acetyltransferase [Desulfobulbus 
propionicus DSM 2032]
Length=400

 Score = 80.9 bits (198),  Expect = 7e-14, Method: Composition-based stats.
 Identities = 37/70 (53%), Positives = 51/70 (73%), Gaps = 0/70 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD+G+  VFG+IYPPQVAL+ FGK ++R  A +G + V   V ATL ADH  +D H
Sbjct  322  VTNLGDRGIKTVFGIIYPPQVALIGFGKISERPWAENGMLGVRRCVTATLAADHRATDGH  381

Query  61   RGALFFLSIN  70
            +GALF  ++N
Sbjct  382  QGALFLEALN  391


>gi|217969836|ref|YP_002355070.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Thauera 
sp. MZ1T]
 gi|217507163|gb|ACK54174.1| Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase [Thauera 
sp. MZ1T]
Length=404

 Score = 80.5 bits (197),  Expect = 8e-14, Method: Compositional matrix adjust.
 Identities = 42/74 (57%), Positives = 51/74 (69%), Gaps = 2/74 (2%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVD--GAIHVMTTVLATLPADHGCSD  58
            +TN+G+QGV+AV GVIYPPQVALV FG+ A R    +  G + VM  V A+L ADH  SD
Sbjct  324  VTNLGEQGVEAVAGVIYPPQVALVGFGRIALRPWVREDRGELCVMPVVTASLAADHRVSD  383

Query  59   DHRGALFFLSINEL  72
             HRGALF   + EL
Sbjct  384  GHRGALFLAELREL  397


>gi|89899199|ref|YP_521670.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Rhodoferax 
ferrireducens T118]
 gi|89343936|gb|ABD68139.1| catalytic domain of components of various dehydrogenase complexes 
[Rhodoferax ferrireducens T118]
Length=417

 Score = 80.1 bits (196),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 39/72 (55%), Positives = 47/72 (66%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+G+Q V +VFGVIYPPQVALV  G  A R     G +H +  + ATL ADH  SD H
Sbjct  324  ITNLGEQSVQSVFGVIYPPQVALVGLGGIAVRPWVEGGKVHALPLLCATLAADHRASDGH  383

Query  61   RGALFFLSINEL  72
            RGALF   + EL
Sbjct  384  RGALFLAELREL  395


>gi|224824123|ref|ZP_03697231.1| catalytic domain of component of various dehydrogenase complexes 
[Lutiella nitroferrum 2002]
 gi|224603542|gb|EEG09717.1| catalytic domain of component of various dehydrogenase complexes 
[Lutiella nitroferrum 2002]
Length=363

 Score = 79.3 bits (194),  Expect = 1e-13, Method: Composition-based stats.
 Identities = 39/72 (55%), Positives = 49/72 (69%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+G+QG ++VFGVIYPPQVALV FGK  +R     G    M +V+A+L  DH  SD H
Sbjct  285  VTNLGEQGSESVFGVIYPPQVALVGFGKVMERPWVEQGQCVAMPSVIASLSGDHRASDGH  344

Query  61   RGALFFLSINEL  72
            RGALF   I +L
Sbjct  345  RGALFLAEIRQL  356


>gi|254380641|ref|ZP_04996007.1| conserved hypothetical protein [Streptomyces sp. Mg1]
 gi|194339552|gb|EDX20518.1| conserved hypothetical protein [Streptomyces sp. Mg1]
Length=443

 Score = 79.3 bits (194),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 41/72 (57%), Positives = 50/72 (70%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GDQGV+AVFGVIYPPQVALV  G+  ++  AV+G + V  TV ATL ADH  SD  
Sbjct  365  VTNLGDQGVEAVFGVIYPPQVALVGLGRVIEQPVAVNGMLTVHPTVTATLSADHRASDGA  424

Query  61   RGALFFLSINEL  72
             GA F   I+ L
Sbjct  425  TGARFLTVIDRL  436


>gi|302039130|ref|YP_003799452.1| putative pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase 
(E2) component [Candidatus Nitrospira defluvii]
 gi|300607194|emb|CBK43527.1| putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase 
(E2) component [Candidatus Nitrospira defluvii]
Length=390

 Score = 78.6 bits (192),  Expect = 3e-13, Method: Composition-based stats.
 Identities = 37/72 (52%), Positives = 49/72 (69%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +T++G+QGV+ VFGVIYPPQVALV FGK  +R    DG +     ++A+L ADH  +D H
Sbjct  312  VTSLGEQGVETVFGVIYPPQVALVGFGKVVERPWVADGLVVPRPVLMASLSADHRVTDGH  371

Query  61   RGALFFLSINEL  72
            RG LF   I+ L
Sbjct  372  RGGLFLAEIDRL  383


>gi|51245946|ref|YP_065830.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Desulfotalea 
psychrophila LSv54]
 gi|50876983|emb|CAG36823.1| probable dihydrolipoamide acetyltransferase, component E2 of 
pyruvate dehydrogenase [Desulfotalea psychrophila LSv54]
Length=397

 Score = 77.4 bits (189),  Expect = 7e-13, Method: Composition-based stats.
 Identities = 37/70 (53%), Positives = 48/70 (69%), Gaps = 0/70 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD GV+ V GVIYPPQVALV FGK  ++  A DG + +   + ATL ADH  +D H
Sbjct  319  ITNLGDLGVEVVHGVIYPPQVALVGFGKILEQPWAKDGMLGIRPILTATLAADHRATDGH  378

Query  61   RGALFFLSIN  70
            RGA F  ++N
Sbjct  379  RGAQFLEALN  388


>gi|116669074|ref|YP_830007.1| dehydrogenase catalytic domain-containing protein [Arthrobacter 
sp. FB24]
 gi|116609183|gb|ABK01907.1| catalytic domain of components of various dehydrogenase complexes 
[Arthrobacter sp. FB24]
Length=477

 Score = 76.3 bits (186),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 39/72 (55%), Positives = 48/72 (67%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD GV+AV+GVIYPPQVA+V  GK  ++  A DG + V   V ATL ADH  SD  
Sbjct  399  VTNLGDLGVEAVYGVIYPPQVAMVGLGKLVEQPWAHDGMLGVRPAVTATLSADHRVSDGL  458

Query  61   RGALFFLSINEL  72
            RG  F   I+EL
Sbjct  459  RGGRFLARIDEL  470


>gi|325961516|ref|YP_004239422.1| pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide 
acyltransferase component [Arthrobacter phenanthrenivorans 
Sphe3]
 gi|323467603|gb|ADX71288.1| pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide 
acyltransferase component [Arthrobacter phenanthrenivorans 
Sphe3]
Length=482

 Score = 75.5 bits (184),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 37/72 (52%), Positives = 49/72 (69%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+G+ GVD+VFGVIYPPQVA+V  G+  ++  A DG + V   V ATL ADH  SD  
Sbjct  404  VTNLGELGVDSVFGVIYPPQVAMVGLGRVMEQAWAHDGMLGVRPVVTATLSADHRVSDGL  463

Query  61   RGALFFLSINEL  72
            RGA +   ++EL
Sbjct  464  RGARYLAQLDEL  475


>gi|119947205|ref|YP_944885.1| pyruvate dehydrogenase complex, E2 component dihydrolipoamide 
acetyltransferase [Psychromonas ingrahamii 37]
 gi|119865809|gb|ABM05286.1| pyruvate dehydrogenase complex, E2 component dihydrolipoamide 
acetyltransferase [Psychromonas ingrahamii 37]
Length=451

 Score = 75.1 bits (183),  Expect = 3e-12, Method: Composition-based stats.
 Identities = 32/72 (45%), Positives = 50/72 (70%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +T++G++G + +F VI+PPQVA+++ G P Q V AVDG+I + + + A+L ADH  SD  
Sbjct  370  VTSIGERGAEQMFAVIFPPQVAILALGSPHQEVMAVDGSIKIRSVIEASLAADHRVSDGR  429

Query  61   RGALFFLSINEL  72
             GA F   +N+L
Sbjct  430  IGARFLYQLNQL  441


>gi|51247011|ref|YP_066894.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Desulfotalea 
psychrophila LSv54]
 gi|50878048|emb|CAG37904.1| probable pyruvate dehydrogenase, E2 component, dihydrolipoamide 
acetyltransferase [Desulfotalea psychrophila LSv54]
Length=397

 Score = 73.6 bits (179),  Expect = 1e-11, Method: Composition-based stats.
 Identities = 35/70 (50%), Positives = 48/70 (69%), Gaps = 0/70 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +T++GD GV+ V GVIYPPQ+ALV FGK  ++  A DG + +   + ATL ADH  +D H
Sbjct  319  ITSLGDLGVEVVHGVIYPPQIALVGFGKILEQPWAKDGMLGIRPILTATLAADHRATDAH  378

Query  61   RGALFFLSIN  70
            RGA F  ++N
Sbjct  379  RGAQFLEALN  388


>gi|148263674|ref|YP_001230380.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Geobacter 
uraniireducens Rf4]
 gi|146397174|gb|ABQ25807.1| catalytic domain of components of various dehydrogenase complexes 
[Geobacter uraniireducens Rf4]
Length=403

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Composition-based stats.
 Identities = 35/71 (50%), Positives = 48/71 (68%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD GV  VFGVIYPPQVALV FG+  +R  A +G + V   + A+L  DH  +D H
Sbjct  325  VTNLGDLGVKTVFGVIYPPQVALVGFGRIMERPWAENGMLGVRRVMSASLAGDHRATDGH  384

Query  61   RGALFFLSINE  71
            RG+ F  ++N+
Sbjct  385  RGSQFLEALNK  395


>gi|291300947|ref|YP_003512225.1| Dihydrolipoyllysine-residue(2-methylpropanoyl) transferase [Stackebrandtia 
nassauensis DSM 44728]
 gi|290570167|gb|ADD43132.1| Dihydrolipoyllysine-residue(2-methylpropanoyl) transferase [Stackebrandtia 
nassauensis DSM 44728]
Length=406

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 38/74 (52%), Positives = 48/74 (65%), Gaps = 0/74 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+GD GVD+V GVIYPPQVALV FG   +R  AV+G + V   V A+L ADH  +D  
Sbjct  328  VSNLGDTGVDSVLGVIYPPQVALVGFGAITERPWAVNGLLGVRPVVTASLSADHRVTDGA  387

Query  61   RGALFFLSINELTR  74
             GA F   I+ L R
Sbjct  388  VGARFLNHIDRLLR  401


>gi|328542713|ref|YP_004302822.1| pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase 
[Polymorphum gilvum SL003B-26A1]
 gi|326412459|gb|ADZ69522.1| Probable pyruvate dehydrogenase, E2 component, dihydrolipoamide 
acetyltransferase [Polymorphum gilvum SL003B-26A1]
Length=411

 Score = 70.9 bits (172),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 34/72 (48%), Positives = 47/72 (66%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++++G++GV+A++GVIYPPQVA+V FG P  R    +G + V   V  TL ADH  SD H
Sbjct  333  VSSLGERGVEALYGVIYPPQVAIVGFGTPISRPWEHEGNLAVRRIVTLTLAADHRVSDGH  392

Query  61   RGALFFLSINEL  72
             GA F   I+ L
Sbjct  393  AGARFLAEISTL  404


>gi|323138355|ref|ZP_08073426.1| Dihydrolipoyllysine-residue acetyltransferase [Methylocystis 
sp. ATCC 49242]
 gi|322396438|gb|EFX98968.1| Dihydrolipoyllysine-residue acetyltransferase [Methylocystis 
sp. ATCC 49242]
Length=383

 Score = 67.0 bits (162),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 32/72 (45%), Positives = 44/72 (62%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +T+VGD+G + V G+IYPPQVA+V FG+   R   VDG I     V+ +L ADH  +D H
Sbjct  305  VTSVGDRGAETVTGIIYPPQVAIVGFGRVVTRPFVVDGRIAPRPLVMVSLAADHRVTDGH  364

Query  61   RGALFFLSINEL  72
             G L+   +  L
Sbjct  365  LGGLYLAEVARL  376


>gi|152992561|ref|YP_001358282.1| pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, 
dihydrolipoamide acetyltransferase [Sulfurovum sp. NBC37-1]
 gi|151424422|dbj|BAF71925.1| pyruvate/2-oxoglutarate dehydrogenase complex, E2 component, 
dihydrolipoamide acetyltransferase [Sulfurovum sp. NBC37-1]
Length=410

 Score = 63.9 bits (154),  Expect = 7e-09, Method: Composition-based stats.
 Identities = 33/72 (46%), Positives = 42/72 (59%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD GV+ V GVIYPPQVALV  G+ A        A+ V   + ATL  DH  +D  
Sbjct  331  ITNLGDIGVEEVLGVIYPPQVALVGLGRIADAPWIEGDALAVRKVMRATLAGDHRATDGR  390

Query  61   RGALFFLSINEL  72
             GALF   ++E 
Sbjct  391  TGALFLNKLDEF  402


>gi|307720480|ref|YP_003891620.1| hypothetical protein Saut_0559 [Sulfurimonas autotrophica DSM 
16294]
 gi|306978573|gb|ADN08608.1| catalytic domain of components of various dehydrogenase complexes 
[Sulfurimonas autotrophica DSM 16294]
Length=385

 Score = 60.5 bits (145),  Expect = 8e-08, Method: Composition-based stats.
 Identities = 29/72 (41%), Positives = 43/72 (60%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+GD GV++V GVIYPPQVA+V  G+   +  A +  + V   V  TL  DH  +D  
Sbjct  306  ITNLGDLGVESVLGVIYPPQVAIVGIGRIIDKPWAENDMLSVRKVVQVTLAGDHRATDGR  365

Query  61   RGALFFLSINEL  72
             GA F   ++++
Sbjct  366  TGAQFLDKLDKI  377


>gi|134098967|ref|YP_001104628.1| pyruvate dehydrogenase, E2 component,dihydrolipoamide acetyltransferase 
[Saccharopolyspora erythraea NRRL 2338]
 gi|291006793|ref|ZP_06564766.1| pyruvate dehydrogenase, E2 component,dihydrolipoamide acetyltransferase 
[Saccharopolyspora erythraea NRRL 2338]
 gi|133911590|emb|CAM01703.1| probable pyruvate dehydrogenase, E2 component,dihydrolipoamide 
acetyltransferase [Saccharopolyspora erythraea NRRL 2338]
Length=434

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 32/68 (48%), Positives = 41/68 (61%), Gaps = 0/68 (0%)

Query  3    NVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRG  62
            N+G+ GV++V GVIYPPQV LV FG   +R  AV   I +   V ATL  DH  SD   G
Sbjct  358  NLGELGVESVQGVIYPPQVGLVGFGAVMRRPWAVGELIGIRPVVTATLSGDHRASDGATG  417

Query  63   ALFFLSIN  70
            A F  +++
Sbjct  418  ARFLNTVD  425


>gi|157375314|ref|YP_001473914.1| dehydrogenase catalytic domain-containing protein [Shewanella 
sediminis HAW-EB3]
 gi|157317688|gb|ABV36786.1| catalytic domain of components of various dehydrogenase complexes 
[Shewanella sediminis HAW-EB3]
Length=377

 Score = 56.2 bits (134),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 28/71 (40%), Positives = 42/71 (60%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+G++G D VF VIYPPQVA++ FGK  + +  VD  +     +   L ADH   D  
Sbjct  299  ITNMGERGTDTVFAVIYPPQVAIIGFGKIRETLQLVDAILVSRDVMSVCLSADHRVIDGM  358

Query  61   RGALFFLSINE  71
             GA F  ++++
Sbjct  359  LGAKFLNALSK  369


>gi|114321742|ref|YP_743425.1| dehydrogenase catalytic domain-containing protein [Alkalilimnicola 
ehrlichii MLHE-1]
 gi|114228136|gb|ABI57935.1| catalytic domain of components of various dehydrogenase complexes 
[Alkalilimnicola ehrlichii MLHE-1]
Length=441

 Score = 53.1 bits (126),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 29/71 (41%), Positives = 42/71 (60%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +T +G++GVD V+GVI+PPQVA++ FG+  +R   V   +     V  +L ADH   D H
Sbjct  363  ITALGERGVDTVYGVIHPPQVAMIGFGRVRRRPVVVGDGLAARPAVDVSLAADHRVCDGH  422

Query  61   RGALFFLSINE  71
             GA F   I +
Sbjct  423  LGARFLNRIEQ  433


>gi|206900930|ref|YP_002250186.1| dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase 
complex [Dictyoglomus thermophilum H-6-12]
 gi|206740033|gb|ACI19091.1| dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase 
complex [Dictyoglomus thermophilum H-6-12]
Length=234

 Score = 52.0 bits (123),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 26/72 (37%), Positives = 39/72 (55%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            + NVG  GV ++  +I PP+VA+V+ G    RV  V+G + +   +  TL ADH   D  
Sbjct  151  VNNVGVFGVRSILAIINPPEVAIVTCGAIQDRVVVVNGEVRIRKMMDITLSADHRVIDGA  210

Query  61   RGALFFLSINEL  72
             G+ F + I E 
Sbjct  211  YGSKFLMKIKEF  222


>gi|298241072|ref|ZP_06964879.1| Dihydrolipoyllysine-residue acetyltransferase [Ktedonobacter 
racemifer DSM 44963]
 gi|297554126|gb|EFH87990.1| Dihydrolipoyllysine-residue acetyltransferase [Ktedonobacter 
racemifer DSM 44963]
Length=435

 Score = 49.7 bits (117),  Expect = 1e-04, Method: Composition-based stats.
 Identities = 26/72 (37%), Positives = 41/72 (57%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G   +DA   +I PPQVA+++ G+ A+RV +V     V  T++ TL  DH   D  
Sbjct  355  ISNLGMYNIDAFNAIIQPPQVAILAVGRIAERVVSVQKQPMVQPTMMLTLSCDHRAVDGA  414

Query  61   RGALFFLSINEL  72
             GA F   + +L
Sbjct  415  LGAKFLSLLADL  426


>gi|90423992|ref|YP_532362.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Rhodopseudomonas 
palustris BisB18]
 gi|90106006|gb|ABD88043.1| Dihydrolipoamide acetyltransferase, long form [Rhodopseudomonas 
palustris BisB18]
Length=455

 Score = 47.0 bits (110),  Expect = 0.001, Method: Composition-based stats.
 Identities = 25/72 (35%), Positives = 36/72 (50%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+     VI PP V +++ G   QR   +DG + V T + ATL  DH   D  
Sbjct  375  VSNLGMFGIKDFAAVINPPHVTILAVGAGEQRAVVIDGKVEVATVMSATLSTDHRAVDGA  434

Query  61   RGALFFLSINEL  72
             GA F  +   L
Sbjct  435  LGAEFLAAFKLL  446


>gi|298506473|gb|ADI85196.1| pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide 
acetyltransferase [Geobacter sulfurreducens KN400]
Length=418

 Score = 46.2 bits (108),  Expect = 0.002, Method: Composition-based stats.
 Identities = 28/74 (38%), Positives = 38/74 (52%), Gaps = 3/74 (4%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+D    VI PPQ A+++ G  A R    DG + V  T+ ATL  DH   D  
Sbjct  338  VSNLGMYGIDEFAAVIMPPQAAILAVGAVADRPVVRDGQLAVARTMRATLSCDHRVVDGA  397

Query  61   RGALFFLSINELTR  74
              A F   + EL R
Sbjct  398  YAAQF---LGELRR  408


>gi|254480044|ref|ZP_05093292.1| 2-oxo acid dehydrogenases acyltransferase (catalytic domain) 
protein [marine gamma proteobacterium HTCC2148]
 gi|214039606|gb|EEB80265.1| 2-oxo acid dehydrogenases acyltransferase (catalytic domain) 
protein [marine gamma proteobacterium HTCC2148]
Length=393

 Score = 46.2 bits (108),  Expect = 0.002, Method: Composition-based stats.
 Identities = 25/71 (36%), Positives = 37/71 (53%), Gaps = 0/71 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  GV +   +I PP  A+++ GK  Q+    DG I + T + ATL  DH   D  
Sbjct  317  VSNLGMFGVSSFTAIINPPMGAILALGKAEQKPVVKDGEIGIATRISATLACDHRVIDGA  376

Query  61   RGALFFLSINE  71
             GA F   + E
Sbjct  377  VGARFLQVLGE  387


>gi|39997530|ref|NP_953481.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Geobacter 
sulfurreducens PCA]
 gi|39984421|gb|AAR35808.1| dehydrogenase complex E2 component, dihydrolipamide acetyltransferase 
[Geobacter sulfurreducens PCA]
Length=418

 Score = 46.2 bits (108),  Expect = 0.002, Method: Composition-based stats.
 Identities = 28/74 (38%), Positives = 38/74 (52%), Gaps = 3/74 (4%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+D    VI PPQ A+++ G  A R    DG + V  T+ ATL  DH   D  
Sbjct  338  VSNLGMYGIDEFAAVIMPPQAAILAVGAVADRPVVRDGQLAVARTMRATLSCDHRVVDGA  397

Query  61   RGALFFLSINELTR  74
              A F   + EL R
Sbjct  398  YAAQF---LGELRR  408


>gi|62185091|ref|YP_219876.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
abortus S26/3]
 gi|62148158|emb|CAH63915.1| dihydrolipoamide acetyltransferase [Chlamydophila abortus S26/3]
Length=429

 Score = 45.8 bits (107),  Expect = 0.002, Method: Composition-based stats.
 Identities = 22/78 (29%), Positives = 41/78 (53%), Gaps = 0/78 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+ A   +I PPQ A+++ G   +    ++G I V +T + TL  DH   D +
Sbjct  348  VSNLGMTGITAFTAIINPPQAAILTVGSVQEEPVVINGEIIVGSTCILTLSIDHRVIDGY  407

Query  61   RGALFFLSINELTRCAAV  78
              A+F   + ++    +V
Sbjct  408  PAAMFMKRLQKILEAPSV  425


>gi|333410240|gb|EGK69227.1| dihydrolipoamide acetyltransferase [Chlamydophila abortus LLG]
Length=429

 Score = 45.8 bits (107),  Expect = 0.002, Method: Composition-based stats.
 Identities = 22/78 (29%), Positives = 41/78 (53%), Gaps = 0/78 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+ A   +I PPQ A+++ G   +    ++G I V +T + TL  DH   D +
Sbjct  348  VSNLGMTGITAFTAIINPPQAAILTVGSVQEEPVVINGEIIVGSTCILTLSIDHRVIDGY  407

Query  61   RGALFFLSINELTRCAAV  78
              A+F   + ++    +V
Sbjct  408  PAAMFMKRLQKILEAPSV  425


>gi|338533851|ref|YP_004667185.1| pyruvate dehydrogenase complex, E2 component, dihydrolipoamide 
acetyltransferase [Myxococcus fulvus HW-1]
 gi|337259947|gb|AEI66107.1| pyruvate dehydrogenase complex, E2 component, dihydrolipoamide 
acetyltransferase [Myxococcus fulvus HW-1]
Length=540

 Score = 45.8 bits (107),  Expect = 0.002, Method: Composition-based stats.
 Identities = 24/72 (34%), Positives = 37/72 (52%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+D    VI PPQ ++++ G  A++    DG + V   + ATL  DH   D  
Sbjct  460  VSNLGMYGIDQFVAVINPPQASILAVGAVAEKAVVRDGQLAVRKVMTATLSCDHRVIDGA  519

Query  61   RGALFFLSINEL  72
             GA F   +  L
Sbjct  520  IGAEFLRELRGL  531


>gi|344925094|ref|ZP_08778555.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Candidatus 
Odyssella thessalonicensis L13]
Length=414

 Score = 45.8 bits (107),  Expect = 0.002, Method: Composition-based stats.
 Identities = 22/72 (31%), Positives = 35/72 (49%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+     +I PPQ  +++ G   QR    +G + + T +  TL ADH   D  
Sbjct  334  ISNLGMYGIRQFAAIINPPQACIMAVGAGEQRAVVAEGQVKIATMMTCTLSADHRVVDGA  393

Query  61   RGALFFLSINEL  72
             GA F  +  E 
Sbjct  394  VGANFLAAFKEF  405


>gi|163793251|ref|ZP_02187227.1| Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide 
acyltransferase (E2) component, and related enzyme [alpha 
proteobacterium BAL199]
 gi|159181897|gb|EDP66409.1| Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide 
acyltransferase (E2) component, and related enzyme [alpha 
proteobacterium BAL199]
Length=429

 Score = 45.4 bits (106),  Expect = 0.002, Method: Composition-based stats.
 Identities = 25/72 (35%), Positives = 37/72 (52%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+     VI PPQ A+++ G   QR    DGA+ + T +  TL  DH   D  
Sbjct  349  ISNLGMFGIKDFAAVINPPQGAILAVGAGEQRAVVKDGALAIATVMSCTLSVDHRVVDGA  408

Query  61   RGALFFLSINEL  72
             GA F  +  +L
Sbjct  409  IGAQFLAAFKKL  420


>gi|334693284|gb|AEG86502.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci 01DC11]
 gi|334694259|gb|AEG87476.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci 02DC15]
 gi|334695236|gb|AEG88452.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci 08DC60]
Length=428

 Score = 45.4 bits (106),  Expect = 0.003, Method: Composition-based stats.
 Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 0/78 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+ A   +I PPQ A+++ G   +    ++G I V +T + TL  DH   D +
Sbjct  347  VSNLGMTGITAFTAIINPPQAAILAVGSVQEEPIVINGEILVGSTCILTLSIDHRVIDGY  406

Query  61   RGALFFLSINELTRCAAV  78
              A+F   + ++    ++
Sbjct  407  PAAMFMKRLQKILEAPSI  424


>gi|15618226|ref|NP_224511.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
pneumoniae CWL029]
 gi|15835841|ref|NP_300365.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
pneumoniae J138]
 gi|16752733|ref|NP_445000.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
pneumoniae AR39]
 6 more sequence titles
 Length=429

 Score = 45.4 bits (106),  Expect = 0.003, Method: Composition-based stats.
 Identities = 21/78 (27%), Positives = 40/78 (52%), Gaps = 0/78 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+     ++ PPQ A+++ G   ++   +DG I + +T   TL  DH   D +
Sbjct  348  VSNLGMTGITEFTAIVNPPQAAILAVGSVTEQALVLDGEITIGSTCNLTLSVDHRVIDGY  407

Query  61   RGALFFLSINELTRCAAV  78
              A+F   + ++    AV
Sbjct  408  PAAMFMKRLQKILEAPAV  425


>gi|329942827|ref|ZP_08291606.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 
[Chlamydophila psittaci Cal10]
 gi|332287420|ref|YP_004422321.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci 6BC]
 gi|313848000|emb|CBY16997.1| dihydrolipoamide acetyltransferase [Chlamydophila psittaci RD1]
 gi|325506640|gb|ADZ18278.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci 6BC]
 gi|328815087|gb|EGF85076.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 
[Chlamydophila psittaci Cal10]
 gi|328914668|gb|AEB55501.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 
[Chlamydophila psittaci 6BC]
 gi|334692304|gb|AEG85523.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Chlamydophila 
psittaci C19/98]
Length=428

 Score = 45.4 bits (106),  Expect = 0.003, Method: Composition-based stats.
 Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 0/78 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+ A   +I PPQ A+++ G   +    ++G I V +T + TL  DH   D +
Sbjct  347  VSNLGMTGITAFTAIINPPQAAILAVGSVQEEPIVINGEILVGSTCILTLSIDHRVIDGY  406

Query  61   RGALFFLSINELTRCAAV  78
              A+F   + ++    ++
Sbjct  407  PAAMFMKRLQKILEAPSI  424


>gi|119900159|ref|YP_935372.1| hypothetical protein azo3870 [Azoarcus sp. BH72]
 gi|119672572|emb|CAL96486.1| hypothetical protein azo3870 [Azoarcus sp. BH72]
Length=237

 Score = 45.4 bits (106),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 27/69 (40%), Positives = 35/69 (51%), Gaps = 0/69 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            +TN+G   VD    +I PPQVA++  G+  Q+    DGAI     V  TL  DH   D +
Sbjct  159  VTNLGSTPVDRFSPIINPPQVAILGVGRTRQQAVVKDGAIVAAPVVNLTLVFDHRAVDGY  218

Query  61   RGALFFLSI  69
              ALF   I
Sbjct  219  PAALFLGEI  227


>gi|108759682|ref|YP_630887.1| pyruvate dehydrogenase complex, E2 component, dihydrolipoamide 
acetyltransferase [Myxococcus xanthus DK 1622]
 gi|108463562|gb|ABF88747.1| pyruvate dehydrogenase complex , E2 component, dihydrolipoamide 
acetyltransferase [Myxococcus xanthus DK 1622]
Length=527

 Score = 44.7 bits (104),  Expect = 0.005, Method: Composition-based stats.
 Identities = 23/72 (32%), Positives = 37/72 (52%), Gaps = 0/72 (0%)

Query  1    MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH  60
            ++N+G  G+D    VI PPQ ++++ G  +++    DG + V   + ATL  DH   D  
Sbjct  447  VSNLGMYGIDQFVAVINPPQASILAVGAVSEKAVVRDGQLAVRKMMTATLSCDHRVIDGA  506

Query  61   RGALFFLSINEL  72
             GA F   +  L
Sbjct  507  IGAEFLRELRGL  518



Lambda     K      H
   0.325    0.138    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 128850890930


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40