BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1743 Length=566 Score E Sequences producing significant alignments: (Bits) Value gi|308231917|ref|ZP_07414267.2| transmembrane serine/threonine-p... 1154 0.0 gi|15608881|ref|NP_216259.1| transmembrane serine/threonine-prot... 1154 0.0 gi|289574414|ref|ZP_06454641.1| transmembrane serine/threonine-p... 1152 0.0 gi|31792931|ref|NP_855424.1| transmembrane serine/threonine-prot... 1151 0.0 gi|340626751|ref|YP_004745203.1| putative transmembrane serine/t... 1150 0.0 gi|306803446|ref|ZP_07440114.1| hypothetical protein TMHG_00925 ... 885 0.0 gi|240169468|ref|ZP_04748127.1| transmembrane serine/threonine-p... 868 0.0 gi|342860681|ref|ZP_08717331.1| putative transmembrane serine/th... 811 0.0 gi|183982591|ref|YP_001850882.1| transmembrane serine/threonine-... 799 0.0 gi|289750302|ref|ZP_06509680.1| transmembrane serine/threonine-p... 768 0.0 gi|118618539|ref|YP_906871.1| transmembrane serine/threonine-pro... 755 0.0 gi|296164638|ref|ZP_06847204.1| possible non-specific serine/thr... 499 4e-139 gi|112491038|pdb|2H34|A Chain A, Apoenzyme Crystal Structure Of ... 498 9e-139 gi|254821942|ref|ZP_05226943.1| transmembrane serine/threonine-p... 484 2e-134 gi|308376810|ref|ZP_07440113.2| putative protein kinase domain p... 466 5e-129 gi|121637194|ref|YP_977417.1| putative transmembrane serine/thre... 429 5e-118 gi|31792458|ref|NP_854951.1| transmembrane serine/threonine-prot... 429 6e-118 gi|339294249|gb|AEJ46360.1| transmembrane serine/threonine-prote... 428 1e-117 gi|342862145|ref|ZP_08718788.1| serine/threonine protein kinase ... 428 2e-117 gi|340626279|ref|YP_004744731.1| putative transmembrane serine/t... 427 2e-117 gi|339297889|gb|AEJ49999.1| putative transmembrane serine/threon... 427 2e-117 gi|289757365|ref|ZP_06516743.1| transmembrane serine/threonine-p... 427 2e-117 gi|289573926|ref|ZP_06454153.1| transmembrane serine/threonine-p... 427 2e-117 gi|15840712|ref|NP_335749.1| serine/threonine protein kinase [My... 427 2e-117 gi|15608406|ref|NP_215782.1| transmembrane serine/threonine-prot... 427 2e-117 gi|289753342|ref|ZP_06512720.1| predicted protein [Mycobacterium... 426 6e-117 gi|289749818|ref|ZP_06509196.1| LOW QUALITY PROTEIN: transmembra... 426 7e-117 gi|289569275|ref|ZP_06449502.1| predicted protein [Mycobacterium... 426 8e-117 gi|289442704|ref|ZP_06432448.1| transmembrane serine/threonine-p... 425 9e-117 gi|340626281|ref|YP_004744733.1| putative serine/threonine-prote... 425 9e-117 gi|296170175|ref|ZP_06851770.1| non-specific serine/threonine pr... 425 1e-116 gi|289446857|ref|ZP_06436601.1| transmembrane serine/threonine-p... 425 1e-116 gi|183984127|ref|YP_001852418.1| transmembrane serine/threonine-... 422 6e-116 gi|307083827|ref|ZP_07492940.1| putative protein kinase domain p... 422 8e-116 gi|240173452|ref|ZP_04752110.1| transmembrane serine/threonine-p... 421 2e-115 gi|289554945|ref|ZP_06444155.1| transmembrane serine/threonine-p... 420 3e-115 gi|254774295|ref|ZP_05215811.1| serine/threonine-protein kinase ... 414 3e-113 gi|118465657|ref|YP_880659.1| serine/threonine protein kinase [M... 414 3e-113 gi|254820140|ref|ZP_05225141.1| serine/threonine-protein kinase ... 412 6e-113 gi|183984142|ref|YP_001852433.1| transmembrane serine/threonine-... 412 8e-113 gi|41408602|ref|NP_961438.1| hypothetical protein MAP2504 [Mycob... 410 2e-112 gi|120405645|ref|YP_955474.1| protein kinase [Mycobacterium vanb... 405 8e-111 gi|145222614|ref|YP_001133292.1| protein kinase [Mycobacterium g... 404 3e-110 gi|240173401|ref|ZP_04752059.1| transmembrane serine/threonine-p... 403 4e-110 gi|315443079|ref|YP_004075958.1| serine/threonine protein kinase... 400 2e-109 gi|240171192|ref|ZP_04749851.1| transmembrane serine/threonine-p... 399 1e-108 gi|183984140|ref|YP_001852431.1| transmembrane serine/threonine-... 399 1e-108 gi|289446860|ref|ZP_06436604.1| transmembrane serine/threonine-p... 393 5e-107 gi|183982458|ref|YP_001850749.1| transmembrane serine/threonine-... 384 2e-104 gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-... 382 7e-104 >gi|308231917|ref|ZP_07414267.2| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis SUMu001] gi|308369514|ref|ZP_07418086.2| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis SUMu002] gi|308370809|ref|ZP_07422805.2| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis SUMu003] 15 more sequence titles Length=571 Score = 1154 bits (2986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 566/566 (100%), Positives = 566/566 (100%), Gaps = 0/566 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 6 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 65 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 66 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 125 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 126 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 185 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 186 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 245 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 246 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 305 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 306 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 365 Query 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA Sbjct 366 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 425 Query 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG Sbjct 426 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 485 Query 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA Sbjct 486 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 545 Query 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 SGTPFVWDGSMVVNYQDPSWLARLIG Sbjct 546 SGTPFVWDGSMVVNYQDPSWLARLIG 571 >gi|15608881|ref|NP_216259.1| transmembrane serine/threonine-protein kinase E [Mycobacterium tuberculosis H37Rv] gi|15841207|ref|NP_336244.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|121637651|ref|YP_977874.1| putative transmembrane serine/threonine-protein kinase E pknE [Mycobacterium bovis BCG str. Pasteur 1173P2] 49 more sequence titles Length=566 Score = 1154 bits (2986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 566/566 (100%), Positives = 566/566 (100%), Gaps = 0/566 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 Query 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA Sbjct 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 Query 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG Sbjct 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 Query 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA Sbjct 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 Query 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 SGTPFVWDGSMVVNYQDPSWLARLIG Sbjct 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 >gi|289574414|ref|ZP_06454641.1| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis K85] gi|339631796|ref|YP_004723438.1| Ser/Thr protein kinase E [Mycobacterium africanum GM041182] gi|289538845|gb|EFD43423.1| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis K85] gi|339331152|emb|CCC26832.1| putative transmembrane serine/threonine-protein kinase E PKNE (protein kinase E) (STPK E) [Mycobacterium africanum GM041182] Length=566 Score = 1152 bits (2981), Expect = 0.0, Method: Compositional matrix adjust. Identities = 565/566 (99%), Positives = 565/566 (99%), Gaps = 0/566 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 Query 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA Sbjct 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 Query 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYS LFG Sbjct 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSTLFG 480 Query 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA Sbjct 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 Query 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 SGTPFVWDGSMVVNYQDPSWLARLIG Sbjct 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 >gi|31792931|ref|NP_855424.1| transmembrane serine/threonine-protein kinase E [Mycobacterium bovis AF2122/97] gi|61214286|sp|Q7TZN3.1|PKNE_MYCBO RecName: Full=Serine/threonine-protein kinase pknE gi|31618522|emb|CAD94474.1| PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE E PKNE (PROTEIN KINASE E) (STPK E) [Mycobacterium bovis AF2122/97] Length=566 Score = 1151 bits (2978), Expect = 0.0, Method: Compositional matrix adjust. Identities = 565/566 (99%), Positives = 565/566 (99%), Gaps = 0/566 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDP FRTR Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPDFRTR 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 Query 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA Sbjct 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 Query 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG Sbjct 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 Query 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA Sbjct 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 Query 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 SGTPFVWDGSMVVNYQDPSWLARLIG Sbjct 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 >gi|340626751|ref|YP_004745203.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium canettii CIPT 140010059] gi|340004941|emb|CCC44089.1| putative transmembrane serine/threonine-protein kinase E PKNE (protein kinase E) (STPK E) [Mycobacterium canettii CIPT 140010059] Length=566 Score = 1150 bits (2974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/566 (99%), Positives = 564/566 (99%), Gaps = 0/566 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAG THRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 121 RQIGSALDAAHAAGVTHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 Query 361 PWRSSGPRTSAPPPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 PWRSSGPRTSAPP PPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA Sbjct 361 PWRSSGPRTSAPPLPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYA 420 Query 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG Sbjct 421 SDIDTAVADKQLAVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFG 480 Query 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA Sbjct 481 SDFQPQENAASDRTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 Query 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 SGTPFVWDGSMVVNYQDPSWLARLIG Sbjct 541 SGTPFVWDGSMVVNYQDPSWLARLIG 566 >gi|306803446|ref|ZP_07440114.1| hypothetical protein TMHG_00925 [Mycobacterium tuberculosis SUMu008] gi|308349883|gb|EFP38734.1| hypothetical protein TMHG_00925 [Mycobacterium tuberculosis SUMu008] Length=446 Score = 885 bits (2288), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/434 (99%), Positives = 434/434 (100%), Gaps = 0/434 (0%) Query 133 AGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSESHA 192 +GATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSESHA Sbjct 13 SGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSESHA 72 Query 193 TYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGIPVAFDAVIARG 252 TYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGIPVAFDAVIARG Sbjct 73 TYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGIPVAFDAVIARG 132 Query 253 MAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPSTHPVSPGTRWPQP 312 MAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPSTHPVSPGTRWPQP Sbjct 133 MAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPSTHPVSPGTRWPQP 192 Query 313 TPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAP 372 TPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAP Sbjct 193 TPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAP 252 Query 373 PPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQL 432 PPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQL Sbjct 253 PPPPPADAVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQL 312 Query 433 AVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASD 492 AVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASD Sbjct 313 AVRYHLLNFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASD 372 Query 493 RTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMV 552 RTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMV Sbjct 373 RTDAELAHLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMV 432 Query 553 VNYQDPSWLARLIG 566 VNYQDPSWLARLIG Sbjct 433 VNYQDPSWLARLIG 446 >gi|240169468|ref|ZP_04748127.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium kansasii ATCC 12478] Length=607 Score = 868 bits (2244), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/606 (77%), Positives = 497/606 (83%), Gaps = 42/606 (6%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA+SREG+QFG YRLRRLVGRG MGDVYEAEDTVRER+VALKLMS TLSSDPVFRTRM Sbjct 3 DTTADSREGSQFGQYRLRRLVGRGAMGDVYEAEDTVRERVVALKLMSPTLSSDPVFRTRM 62 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRL EPHVVPIHD+GEIDGQLYVDMRLI+G DLAA+L+R GPL PPRAVA+VR Sbjct 63 QREARTAGRLHEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAILKRYGPLTPPRAVAVVR 122 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAHAAG THRDVKPENILVS DDFAYLVDFGIASAT+DEKLTQLG+TVGTLYY Sbjct 123 QIGSALDAAHAAGVTHRDVKPENILVSGDDFAYLVDFGIASATSDEKLTQLGSTVGTLYY 182 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERF+ + TYRADIYAL CVLYECLTGSPPY+GDQLSVMGAH++QAIPRPS RPGI Sbjct 183 MAPERFANTEVTYRADIYALACVLYECLTGSPPYRGDQLSVMGAHLSQAIPRPSAARPGI 242 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPV---- 297 P AFD VIARGMAK+P DRY TCGDLSAAA+AALAT DQDRATDIL+RSQVA+LP Sbjct 243 PAAFDQVIARGMAKDPADRYATCGDLSAAAYAALATPDQDRATDILQRSQVAQLPAAAVG 302 Query 298 --------PSTHPVSPGTR---W--------------PQPTPWAG------------GAP 320 P P +P + W PQPTPW G GAP Sbjct 303 QPAAGFAPPMPTPSTPAAQPAGWSPPTPPGSPVPTGAPQPTPWTGATGWGTGYPGTAGAP 362 Query 321 PWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAPPPPPPADA 380 PWG P PWLWVGVAVAVVVA+A GLGI +A PWRSS PR P PP ADA Sbjct 363 PWGQPPVQPSGGGGAPWLWVGVAVAVVVAVAAGLGIVVAKPWRSSAPR-PGPTSPPAADA 421 Query 381 VELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQLAVRYHLLN 440 VELRVLNDGVFVGSS A TTIDIFNEPICPPCG+FIRSYASDI+TAVADK+LAVRYHLLN Sbjct 422 VELRVLNDGVFVGSSAAATTIDIFNEPICPPCGAFIRSYASDIETAVADKKLAVRYHLLN 481 Query 441 FLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASDRTDAELAH 500 FLDDQSH+KNYSTRAVAASYCVA QNDPK+Y+ FY+ALFGSDFQPQE AASDRTDAELAH Sbjct 482 FLDDQSHTKNYSTRAVAASYCVADQNDPKVYSDFYAALFGSDFQPQEGAASDRTDAELAH 541 Query 501 LAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMVVNYQDPSW 560 LAQTVGA TAISCIKSG+D GTAQ+KA ASETLA F+A+GTPFVWDG V+ Q+ SW Sbjct 542 LAQTVGANTTAISCIKSGSDRGTAQSKAAAASETLATFSANGTPFVWDGKKAVDLQNSSW 601 Query 561 LARLIG 566 L RL G Sbjct 602 LTRLTG 607 >gi|342860681|ref|ZP_08717331.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium colombiense CECT 3035] gi|342131705|gb|EGT84962.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium colombiense CECT 3035] Length=601 Score = 811 bits (2096), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/603 (70%), Positives = 470/603 (78%), Gaps = 44/603 (7%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA+SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMS TLS+DPVFR+RM Sbjct 5 DATADSREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSRTLSNDPVFRSRM 64 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRL EPHVVPIHDFGEIDGQLYVDMRLI+G DLA+ML+R GP++PPRA+AIVR Sbjct 65 QREARTAGRLHEPHVVPIHDFGEIDGQLYVDMRLIDGKDLASMLKRYGPISPPRAIAIVR 124 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAH AG HRDVKPENILVSADDFAYLVDFGIASAT+DEKLTQ G TVGT Y Sbjct 125 QIGSALDAAHTAGILHRDVKPENILVSADDFAYLVDFGIASATSDEKLTQFGTTVGTAKY 184 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERF +S T +ADIYAL CVLYECLTGSPPY GDQLSVMGAH++Q IPRPS RP I Sbjct 185 MAPERFGDSEITAKADIYALACVLYECLTGSPPYTGDQLSVMGAHMHQPIPRPSAARPSI 244 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPV---- 297 P AFD VIARGMAK+P DR++TCGDLSAAA+ ALA DQDRATDIL RSQ+A P Sbjct 245 PAAFDGVIARGMAKDPADRFLTCGDLSAAAYGALAAPDQDRATDILERSQMATPPAAFAG 304 Query 298 --------------------------PSTHPVSPGTRWPQPTPW--------AGGAPPWG 323 P+ P++ G QP W AG PPWG Sbjct 305 QPAGGFAPGPPVAAPAPPPLGGWPAPPAAQPLTAGAPGLQPAAWGGPPVWTNAGATPPWG 364 Query 324 PPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAPPPPPPADAVEL 383 P PRS+R+PWLWVGVA + VAL G + + + PW S R + PPPPP DAV L Sbjct 365 QP----PRSSRKPWLWVGVAATLTVALIGVI-LGVVRPWESK-TRPAPAPPPPPPDAVAL 418 Query 384 RVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQLAVRYHLLNFLD 443 RVL+DGVFVGSS A TTID+FNEPICPPCGSFIRS A+DIDTAV +K+LAVRYHLLNFLD Sbjct 419 RVLDDGVFVGSSAAQTTIDVFNEPICPPCGSFIRSNATDIDTAVNNKKLAVRYHLLNFLD 478 Query 444 DQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASDRTDAELAHLAQ 503 D+SHS++YSTRAVAA+YCVAGQNDPK+Y FYS LF S FQPQE AA DRTD ELA LA+ Sbjct 479 DKSHSQDYSTRAVAATYCVAGQNDPKVYVDFYSGLFASSFQPQEGAAEDRTDGELAQLAK 538 Query 504 TVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMVVNYQDPSWLAR 563 TVGA+ ++CIKSG D+GTA+ KA N TL+ NA+ TPFVWDG+ VNYQ+P+WL + Sbjct 539 TVGADGAVVACIKSGDDIGTAKAKAANGYSTLSADNANSTPFVWDGTTAVNYQNPAWLTK 598 Query 564 LIG 566 L G Sbjct 599 LTG 601 >gi|183982591|ref|YP_001850882.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium marinum M] gi|183175917|gb|ACC41027.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium marinum M] Length=608 Score = 799 bits (2063), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/607 (74%), Positives = 492/607 (82%), Gaps = 43/607 (7%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA+SREG+QFGPYRLRR+VGRG MGDVYEAEDTVRER+VALKLMS+TLS+DPVFRTRM Sbjct 3 DATADSREGSQFGPYRLRRIVGRGAMGDVYEAEDTVRERVVALKLMSQTLSNDPVFRTRM 62 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRLQEPHVVPIHD+GEIDGQLYVDMRLI+G DLAAML+R GPL PPRAVAI R Sbjct 63 QREARTAGRLQEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAMLKRYGPLPPPRAVAITR 122 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAHAAG THRDVKPENILVS DDFAYLVDFGIASAT+DEKLTQLG+TVGTLYY Sbjct 123 QIGSALDAAHAAGVTHRDVKPENILVSHDDFAYLVDFGIASATSDEKLTQLGSTVGTLYY 182 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERFS TYRADIYAL CVLYECLTGSPPY+GDQLSVMGAH++Q IPRPS RPGI Sbjct 183 MAPERFSSGDVTYRADIYALACVLYECLTGSPPYRGDQLSVMGAHLSQPIPRPSAARPGI 242 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP----- 296 P FD VIARGMAK+P DRY TCGDLSAAA++ALAT DQDRATDIL+RSQVA+LP Sbjct 243 PAGFDNVIARGMAKDPADRYATCGDLSAAAYSALATPDQDRATDILQRSQVAQLPAGFAS 302 Query 297 ------VPSTHPV-----SPGTRWPQ--------------PTPWAGGAPPWG-------- 323 PS+ V +P T WP PTPWA G P WG Sbjct 303 TPPGGFAPSSPAVPVPGSAPSTGWPAPSVPGAPVAPSAPVPTPWA-GVPGWGVGHTGTTG 361 Query 324 ----PPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAPPPPPPAD 379 P P A + W W+ AVAVVV +AG LG+ +AHPWRS GP T++ PPPPP D Sbjct 362 APPWGQPPPQPTVAAKTWPWIAAAVAVVVVIAGVLGVVIAHPWRSPGPPTASAPPPPPPD 421 Query 380 AVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQLAVRYHLL 439 AV+LRVLNDGVF+GSS A TTIDIFNEPICPPCG+FIRSYASDID AVA+K+LAVRYHLL Sbjct 422 AVQLRVLNDGVFIGSSAATTTIDIFNEPICPPCGAFIRSYASDIDAAVANKKLAVRYHLL 481 Query 440 NFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASDRTDAELA 499 NFLD+QSH+K YSTRAVAASYCVA Q+DPK+Y FY+ALF SDFQPQE AASDRTDAELA Sbjct 482 NFLDEQSHTKTYSTRAVAASYCVAAQDDPKVYTDFYAALFASDFQPQEAAASDRTDAELA 541 Query 500 HLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNASGTPFVWDGSMVVNYQDPS 559 HLAQTVGA TA SCIK+G D+GTA+TKA A TL+ NASGTPFVWDGS ++ Q+PS Sbjct 542 HLAQTVGANGTATSCIKAGNDMGTARTKAAAADATLSELNASGTPFVWDGSKSIDLQNPS 601 Query 560 WLARLIG 566 WL +LIG Sbjct 602 WLTKLIG 608 >gi|289750302|ref|ZP_06509680.1| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis T92] gi|289690889|gb|EFD58318.1| transmembrane serine/threonine-protein kinase E pknE [Mycobacterium tuberculosis T92] Length=462 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/379 (99%), Positives = 379/379 (100%), Gaps = 0/379 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST Sbjct 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH Sbjct 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 Query 361 PWRSSGPRTSAPPPPPPAD 379 PWRSSGPRTSAPPPPPPA+ Sbjct 361 PWRSSGPRTSAPPPPPPAE 379 >gi|118618539|ref|YP_906871.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium ulcerans Agy99] gi|118570649|gb|ABL05400.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium ulcerans Agy99] Length=587 Score = 755 bits (1949), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/581 (74%), Positives = 470/581 (81%), Gaps = 43/581 (7%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA+SREG+QFGPYRLRR+VGRG MGDVYEAEDTVRER+VALKLMS+TLS+DPVFRTRM Sbjct 3 DATADSREGSQFGPYRLRRIVGRGAMGDVYEAEDTVRERVVALKLMSQTLSNDPVFRTRM 62 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRLQEPHVVPIHD+GEIDGQLYVDMRLI+G DLAAML+R GPL PPRAVAI R Sbjct 63 QREARTAGRLQEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAMLKRYGPLPPPRAVAITR 122 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAHAAG THRDVKPENILVS DDFAYLVDFGIASAT+DEKLTQLG+TVGTLYY Sbjct 123 QIGSALDAAHAAGVTHRDVKPENILVSHDDFAYLVDFGIASATSDEKLTQLGSTVGTLYY 182 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERFS TYRADIYAL CVLYECLTGSPPY+GDQLSV+GAH++Q IPRPS RPGI Sbjct 183 MAPERFSSGDVTYRADIYALACVLYECLTGSPPYRGDQLSVIGAHLSQPIPRPSAARPGI 242 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP----- 296 P FD VIARGMAK+P DRY TCGDLSAAA++ALAT DQDRATDIL+RSQVA+LP Sbjct 243 PAGFDNVIARGMAKDPADRYATCGDLSAAAYSALATPDQDRATDILQRSQVAQLPAGFAS 302 Query 297 ------VPSTHPV-----SPGTRWPQ--------------PTPWAGGAPPWG-------- 323 PS+ V +P T WP PTPWA G P WG Sbjct 303 TSPGGFAPSSPAVPVPGSAPSTGWPAPSVPGAPVAPSAPVPTPWA-GVPGWGVGHTGTTG 361 Query 324 ----PPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAHPWRSSGPRTSAPPPPPPAD 379 P P A + W W+ AVAVVV +AG LG+ +AHPWRS GP T++ PPPPP D Sbjct 362 APPWGQPPPEPTVAAKTWPWIAAAVAVVVVIAGVLGVVIAHPWRSPGPPTASAPPPPPPD 421 Query 380 AVELRVLNDGVFVGSSVAPTTIDIFNEPICPPCGSFIRSYASDIDTAVADKQLAVRYHLL 439 AV+LRVLNDGVF+GSS A TTIDIFNEPICPPCG+FIRSYASDID AVA+K+LAVRYHLL Sbjct 422 AVQLRVLNDGVFIGSSAATTTIDIFNEPICPPCGAFIRSYASDIDAAVANKKLAVRYHLL 481 Query 440 NFLDDQSHSKNYSTRAVAASYCVAGQNDPKLYASFYSALFGSDFQPQENAASDRTDAELA 499 NFLD+QSH+K YSTRAVAASYCVA Q+DPK+Y FY+ALF SDFQPQE AASDRTDAELA Sbjct 482 NFLDEQSHTKTYSTRAVAASYCVAAQDDPKVYTDFYAALFASDFQPQEAAASDRTDAELA 541 Query 500 HLAQTVGAEPTAISCIKSGADLGTAQTKATNASETLAGFNA 540 HLAQTVGA TA SCIK+G D+GTA+TKA A TL+ NA Sbjct 542 HLAQTVGANGTATSCIKAGNDMGTARTKAAAADATLSELNA 582 >gi|296164638|ref|ZP_06847204.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899946|gb|EFG79386.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=318 Score = 499 bits (1286), Expect = 4e-139, Method: Compositional matrix adjust. Identities = 249/295 (85%), Positives = 271/295 (92%), Gaps = 0/295 (0%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA+SREG+QFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMS+TLS+DPVFR+RM Sbjct 3 DTTADSREGSQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSQTLSNDPVFRSRM 62 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLI+G DLA ML R G L+PPRAVAIVR Sbjct 63 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLIDGKDLAGMLSRYGALSPPRAVAIVR 122 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAHAAG HRDVKPENILVS+DDFAYLVDFGIASA+ DEKLTQ+G TVGT+ Y Sbjct 123 QIGSALDAAHAAGVLHRDVKPENILVSSDDFAYLVDFGIASASADEKLTQIGTTVGTVKY 182 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERFS+S T+RADIYAL CVLYECLTGSPPY GDQ+ V+GAH++QAIP+PS RPGI Sbjct 183 MAPERFSDSEVTHRADIYALGCVLYECLTGSPPYTGDQIGVIGAHLHQAIPQPSAARPGI 242 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP 296 P AFDAVIARGMAKNP DRY TCGDLSAAA+AALA D+DRATDIL+RSQVA+ P Sbjct 243 PAAFDAVIARGMAKNPADRYATCGDLSAAAYAALAEPDRDRATDILQRSQVARPP 297 >gi|112491038|pdb|2H34|A Chain A, Apoenzyme Crystal Structure Of The Tuberculosis SerineTHREONINE KINASE, PKNE gi|112491039|pdb|2H34|B Chain B, Apoenzyme Crystal Structure Of The Tuberculosis SerineTHREONINE KINASE, PKNE Length=309 Score = 498 bits (1283), Expect = 9e-139, Method: Compositional matrix adjust. Identities = 281/289 (98%), Positives = 281/289 (98%), Gaps = 0/289 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGG GDVYEAEDTVRERIVALKL SETLSSDPVFRTR Sbjct 21 MDGTAESREGTQFGPYRLRRLVGRGGXGDVYEAEDTVRERIVALKLXSETLSSDPVFRTR 80 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 QREARTAGRLQEPHVVPIHDFGEIDGQLYVD RLINGVDLAA LRRQGPLAPPRAVAIV Sbjct 81 XQREARTAGRLQEPHVVPIHDFGEIDGQLYVDXRLINGVDLAAXLRRQGPLAPPRAVAIV 140 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 141 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 200 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPG 240 Y APERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSV GAHINQAIPRPSTVRPG Sbjct 201 YXAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVXGAHINQAIPRPSTVRPG 260 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRR 289 IPVAFDAVIARG AKNPEDRYVTCGDLSAAAHAALATADQDRATDILRR Sbjct 261 IPVAFDAVIARGXAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRR 309 >gi|254821942|ref|ZP_05226943.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium intracellulare ATCC 13950] Length=326 Score = 484 bits (1246), Expect = 2e-134, Method: Compositional matrix adjust. Identities = 242/295 (83%), Positives = 265/295 (90%), Gaps = 0/295 (0%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D TA++R G+QFGPY LRRLVGRGGMGDVYEAEDTVRER+VALKLMS TLS+DPVFR+RM Sbjct 12 DTTADTRAGSQFGPYLLRRLVGRGGMGDVYEAEDTVRERVVALKLMSPTLSNDPVFRSRM 71 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREARTAGRL EPHVVPIHDFGEIDGQLYVDMRL++G DLA ML+R GPL+PPRAVAIVR Sbjct 72 QREARTAGRLHEPHVVPIHDFGEIDGQLYVDMRLVDGKDLAGMLKRYGPLSPPRAVAIVR 131 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 QIGSALDAAHAAG HRDVKPENILVSADDFAYLVDFGIASAT+DEKLTQ+G TVGT Y Sbjct 132 QIGSALDAAHAAGILHRDVKPENILVSADDFAYLVDFGIASATSDEKLTQIGTTVGTAKY 191 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAHINQAIPRPSTVRPGI 241 MAPERF +S T+RADIYAL CVLYECLTGSPPY GDQLSV+GAH++Q IPRPS RP I Sbjct 192 MAPERFGDSQVTHRADIYALACVLYECLTGSPPYTGDQLSVIGAHVHQPIPRPSAARPSI 251 Query 242 PVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP 296 P FD VIARGMAKNP+DRY+TCGDLS+AA+AALA DQDRATDIL R+Q+A P Sbjct 252 PAGFDEVIARGMAKNPDDRYLTCGDLSSAAYAALAAPDQDRATDILARTQMATPP 306 >gi|308376810|ref|ZP_07440113.2| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu008] gi|308349961|gb|EFP38812.1| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu008] Length=231 Score = 466 bits (1199), Expect = 5e-129, Method: Compositional matrix adjust. Identities = 226/226 (100%), Positives = 226/226 (100%), Gaps = 0/226 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR Sbjct 6 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 65 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV Sbjct 66 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 125 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY Sbjct 126 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 185 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAH 226 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAH Sbjct 186 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVMGAH 231 >gi|121637194|ref|YP_977417.1| putative transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989669|ref|YP_002644356.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium bovis BCG str. Tokyo 172] gi|121492841|emb|CAL71312.1| Probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772782|dbj|BAH25588.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium bovis BCG str. Tokyo 172] gi|341601212|emb|CCC63885.1| probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Moreau RDJ] Length=596 Score = 429 bits (1104), Expect = 5e-118, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 300 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 301 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 341 >gi|31792458|ref|NP_854951.1| transmembrane serine/threonine-protein kinase H [Mycobacterium bovis AF2122/97] gi|61214289|sp|Q7U095.1|PKNH_MYCBO RecName: Full=Probable serine/threonine-protein kinase pknH gi|31618047|emb|CAD94158.1| PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE H PKNH (PROTEIN KINASE H) (STPK H) [Mycobacterium bovis AF2122/97] Length=596 Score = 429 bits (1103), Expect = 6e-118, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 300 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 301 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 341 >gi|339294249|gb|AEJ46360.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CCDC5079] Length=638 Score = 428 bits (1100), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 13 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 72 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 73 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 132 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 133 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 192 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 193 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 252 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 253 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 312 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 313 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 370 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 371 PNSGPMPASGPTP 383 >gi|342862145|ref|ZP_08718788.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] gi|342130449|gb|EGT83764.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] Length=624 Score = 428 bits (1100), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 203/298 (69%), Positives = 241/298 (81%), Gaps = 1/298 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KL+SE+ S DPVFR R Sbjct 1 MSDEQSSRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 ++REARTAGRLQEPHVVP+HD+GEIDGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 LKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRD+KP+NIL++ DDFAYLVDFGIASATTD+KLTQLG VGT Sbjct 121 TQIASALDAAHAGGVMHRDIKPQNILLTRDDFAYLVDFGIASATTDDKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS++ TYRADIYAL CVL+ECLTG+PPY+ D V+ AH+ + IP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGTPPYRADSAGVLVSAHMMEPIPAPSEQRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPV 297 G+P AFDAVIARGMAK PEDRY + GDL+ AA AL+ DQDRA ILRRSQ A LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKQALSNPDQDRAATILRRSQEAALPT 298 >gi|340626279|ref|YP_004744731.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium canettii CIPT 140010059] gi|340004469|emb|CCC43612.1| putative transmembrane serine/threonine-protein kinase H PKNH (protein kinase H) (STPK H) [Mycobacterium canettii CIPT 140010059] Length=626 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGAQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 358 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 359 PNSGPMPASGPTP 371 >gi|339297889|gb|AEJ49999.1| putative transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CCDC5180] Length=641 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 16 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 75 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 76 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 135 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 136 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 195 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 196 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 255 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 256 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 315 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 316 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 373 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 374 PNSGPMPASGPTP 386 >gi|289757365|ref|ZP_06516743.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] gi|289712929|gb|EFD76941.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] Length=314 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 203/300 (68%), Positives = 242/300 (81%), Gaps = 1/300 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 15 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 74 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 75 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 134 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 135 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 194 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 195 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 254 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP P+ Sbjct 255 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPA 314 >gi|289573926|ref|ZP_06454153.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis K85] gi|339631332|ref|YP_004722974.1| Ser/Thr protein kinase [Mycobacterium africanum GM041182] gi|289538357|gb|EFD42935.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis K85] gi|339330688|emb|CCC26357.1| putative membrane spanning serine/threonine protein kinase [Mycobacterium africanum GM041182] Length=626 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVIPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 358 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 359 PNSGPMPASGPTP 371 >gi|15840712|ref|NP_335749.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|148661053|ref|YP_001282576.1| serine/threonine protein kinase [Mycobacterium tuberculosis H37Ra] gi|148822483|ref|YP_001287237.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis F11] 48 more sequence titles Length=626 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 358 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 359 PNSGPMPASGPTP 371 >gi|15608406|ref|NP_215782.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis H37Rv] gi|6093725|sp|Q11053.2|PKNH_MYCTU RecName: Full=Probable serine/threonine-protein kinase pknH gi|3261596|emb|CAB00914.1| PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE H PKNH (PROTEIN KINASE H) (STPK H) [Mycobacterium tuberculosis H37Rv] Length=626 Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 219/373 (59%), Positives = 259/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 358 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 359 PNSGPMPASGPTP 371 >gi|289753342|ref|ZP_06512720.1| predicted protein [Mycobacterium tuberculosis EAS054] gi|289693929|gb|EFD61358.1| predicted protein [Mycobacterium tuberculosis EAS054] Length=319 Score = 426 bits (1094), Expect = 6e-117, Method: Compositional matrix adjust. Identities = 203/297 (69%), Positives = 240/297 (81%), Gaps = 1/297 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 16 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 75 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 76 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 135 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 136 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 195 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 196 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 255 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ AK P Sbjct 256 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQAAKNP 312 >gi|289749818|ref|ZP_06509196.1| LOW QUALITY PROTEIN: transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] gi|289690405|gb|EFD57834.1| LOW QUALITY PROTEIN: transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] Length=490 Score = 426 bits (1094), Expect = 7e-117, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 17 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 76 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 77 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 136 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 137 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 196 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 197 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 256 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 257 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 316 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 317 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 357 >gi|289569275|ref|ZP_06449502.1| predicted protein [Mycobacterium tuberculosis T17] gi|289543029|gb|EFD46677.1| predicted protein [Mycobacterium tuberculosis T17] Length=588 Score = 426 bits (1094), Expect = 8e-117, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 13 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 72 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 73 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 132 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 133 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 192 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 193 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 252 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 253 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 312 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 313 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 353 >gi|289442704|ref|ZP_06432448.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis T46] gi|289415623|gb|EFD12863.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis T46] Length=576 Score = 425 bits (1093), Expect = 9e-117, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 300 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 301 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 341 >gi|340626281|ref|YP_004744733.1| putative serine/threonine-protein kinase pknh [Mycobacterium canettii CIPT 140010059] gi|340004471|emb|CCC43614.1| putative serine/threonine-protein kinase pknh [Mycobacterium canettii CIPT 140010059] Length=576 Score = 425 bits (1093), Expect = 9e-117, Method: Compositional matrix adjust. Identities = 215/341 (64%), Positives = 255/341 (75%), Gaps = 5/341 (1%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGTA 300 Query 297 -VPSTHPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 V + P P P G P W P S P+P S P Sbjct 301 AVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTP 341 >gi|296170175|ref|ZP_06851770.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895167|gb|EFG74883.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=625 Score = 425 bits (1093), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 228/365 (63%), Positives = 262/365 (72%), Gaps = 39/365 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M SR G+ FGPYRL+RL+GRGGMG+VYEAE TV+E VA+KL+SE+ S DPVFR R Sbjct 1 MSDEQASRVGSNFGPYRLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVPIHD+GEIDGQ++++MRLI G DL ++L+R GPLAPPRAVAI+ Sbjct 61 MKREARTAGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTDLDSVLKRFGPLAPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHAAG HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS + TYRADIYAL CVLYECLTG+PPY+ D SV+ AH+ IP+P+ +RP Sbjct 181 YMAPERFSNAEVTYRADIYALACVLYECLTGTPPYRADSASVLVTAHMMDPIPQPTALRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 GIP AFDAVIARGMAK P+DRY + GDL+ AAH AL+ DQD A ILRRSQ A LP Sbjct 241 GIPKAFDAVIARGMAKKPQDRYASAGDLALAAHDALSDPDQDHAATILRRSQEATLP--- 297 Query 300 THPVSPGTRWPQPTPW-------------------------------AGGAPPWGPPSSP 328 T PQPT A GAPPW P S P Sbjct 298 ----GTATLGPQPTVADTAMAPPATPPSPAPTANTPPPSAAGLTPVPAQGAPPWRPESGP 353 Query 329 LPRSA 333 P +A Sbjct 354 FPSAA 358 >gi|289446857|ref|ZP_06436601.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] gi|289419815|gb|EFD17016.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] Length=626 Score = 425 bits (1092), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 218/373 (59%), Positives = 258/373 (70%), Gaps = 39/373 (10%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M + R G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDLRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---- 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 296 -------------------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWG 323 P PS T P PG +P P G P W Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWA 358 Query 324 PPSSPLPRSARQP 336 P S P+P S P Sbjct 359 PNSGPMPASGPTP 371 >gi|183984127|ref|YP_001852418.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium marinum M] gi|183177453|gb|ACC42563.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium marinum M] Length=596 Score = 422 bits (1086), Expect = 6e-116, Method: Compositional matrix adjust. Identities = 217/354 (62%), Positives = 257/354 (73%), Gaps = 19/354 (5%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MGEAPDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTTEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GEIDGQ++++MRLI G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTDLDSILKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP NIL++ DDFAYLVDFGIASAT DEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPPNILITRDDFAYLVDFGIASATGDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERF+ TYRADIYAL CVL+ECLTGSPPY+ D +++ AH+ +P+ STVR Sbjct 181 YMAPERFANEEVTYRADIYALACVLFECLTGSPPYRSDSAGTLVTAHLMDPVPQVSTVRS 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP--- 296 GIP AFDAVIARGMAK PE+RY + GDL+ AAH AL+ DQD A DILRRS+ + LP Sbjct 241 GIPKAFDAVIARGMAKKPEERYASAGDLARAAHDALSNPDQDHAADILRRSRESTLPGTA 300 Query 297 --------VPSTHP------VSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 +P+ P P + P P G P W P S P+P +A QP Sbjct 301 AITPQPPTMPAVTPPPAMPYADPASSGPLPQSAPTGQPGWAPASGPIP-AAHQP 353 >gi|307083827|ref|ZP_07492940.1| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu012] gi|308366510|gb|EFP55361.1| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu012] Length=353 Score = 422 bits (1085), Expect = 8e-116, Method: Compositional matrix adjust. Identities = 201/296 (68%), Positives = 239/296 (81%), Gaps = 1/296 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL 295 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTL 296 >gi|240173452|ref|ZP_04752110.1| transmembrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=353 Score = 421 bits (1082), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 216/295 (74%), Positives = 242/295 (83%), Gaps = 1/295 (0%) Query 7 SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREAR 66 SR G+ FGPYRL+RL+GRGGMG+VYEAE TV+E VA+KLMSET S DPVFR RM+REAR Sbjct 7 SRVGSTFGPYRLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMSETFSKDPVFRERMKREAR 66 Query 67 TAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSA 126 GRLQEPHVVPIHD+GEIDGQ+Y++MRLI G DL +L+R GPL PPRAVAI+ QI SA Sbjct 67 ITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDHILKRFGPLTPPRAVAIITQIASA 126 Query 127 LDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPER 186 LDAAHAAG HRDVKP+NILV+ DDFAYLVDFGIASATTDEKLTQLG VGT YMAPER Sbjct 127 LDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPER 186 Query 187 FSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRPGIPVAF 245 FS TYRADIYAL CVL+ECLTGSPPY+ D S++ AH+ IP+PST+R GIP AF Sbjct 187 FSNDEVTYRADIYALACVLHECLTGSPPYRADSASMLVTAHLMDPIPQPSTLRSGIPKAF 246 Query 246 DAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 DAVIARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ A LP P T Sbjct 247 DAVIARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQEATLPGPPT 301 >gi|289554945|ref|ZP_06444155.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis KZN 605] gi|289439577|gb|EFD22070.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis KZN 605] Length=615 Score = 420 bits (1080), Expect = 3e-115, Method: Compositional matrix adjust. Identities = 215/361 (60%), Positives = 253/361 (71%), Gaps = 39/361 (10%) Query 13 FGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREARTAGRLQ 72 FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR RM+REAR AGRLQ Sbjct 2 FGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIAGRLQ 61 Query 73 EPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSALDAAHA 132 EPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ QI SALDAAHA Sbjct 62 EPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAHA 121 Query 133 AGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSESHA 192 G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT YMAPERFS Sbjct 122 DGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEV 181 Query 193 TYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRPGIPVAFDAVIAR 251 TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RPGIP AFDAV+AR Sbjct 182 TYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVAR 241 Query 252 GMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL---------------- 295 GMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + L Sbjct 242 GMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATA 301 Query 296 -------------------PVPS-THPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQ 335 P PS T P PG +P P G P W P S P+P S Sbjct 302 MAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGP--TGQPSWAPNSGPMPASGPT 359 Query 336 P 336 P Sbjct 360 P 360 >gi|254774295|ref|ZP_05215811.1| serine/threonine-protein kinase PknE [Mycobacterium avium subsp. avium ATCC 25291] Length=604 Score = 414 bits (1063), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 221/347 (64%), Positives = 258/347 (75%), Gaps = 13/347 (3%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M S+ G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KL++E+ SSDPVFR R Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVP+HD+GEIDGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHAAG HRDVKP+NILV+ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS++ TYRADIYAL CVL+ECLTGS PY+ D V+ AH+ IP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 G+P AFDAVIARGMAK PEDRY + GDL+ AA AL+T DQDRA ILRRSQ A LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG 300 Query 300 TH----------PVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 P + TR P G W P S P+P +A QP Sbjct 301 QRDAGASTVLAPPPAVNTRQPGSAASQAGR-GWTPESGPIP-AAGQP 345 >gi|118465657|ref|YP_880659.1| serine/threonine protein kinase [Mycobacterium avium 104] gi|118166944|gb|ABK67841.1| serine/threonine-protein kinase PknE [Mycobacterium avium 104] gi|336458610|gb|EGO37577.1| protein kinase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=604 Score = 414 bits (1063), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 221/347 (64%), Positives = 258/347 (75%), Gaps = 13/347 (3%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M S+ G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KL++E+ SSDPVFR R Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVP+HD+GEIDGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHAAG HRDVKP+NILV+ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS++ TYRADIYAL CVL+ECLTGS PY+ D V+ AH+ IP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 G+P AFDAVIARGMAK PEDRY + GDL+ AA AL+T DQDRA ILRRSQ A LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG 300 Query 300 TH----------PVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 P + TR P G W P S P+P +A QP Sbjct 301 QRDAGASTVLAPPPAVNTRQPGSAASQAGR-GWTPESGPIP-AAGQP 345 >gi|254820140|ref|ZP_05225141.1| serine/threonine-protein kinase PknE [Mycobacterium intracellulare ATCC 13950] Length=588 Score = 412 bits (1060), Expect = 6e-113, Method: Compositional matrix adjust. Identities = 232/388 (60%), Positives = 266/388 (69%), Gaps = 33/388 (8%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KL+SE+ S DPVFR R Sbjct 1 MSDEQASRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVP+HD+GEIDGQ++++MRL+ G DL ++L+R GPL PPRAVA++ Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQIFLEMRLVEGTDLGSVLKRFGPLTPPRAVAVI 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHAAG HRDVKP+NILV+ADDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTADDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS++ TYRADIYAL CVL+ECLTG+PPY+ D ++ AH+ IP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGAPPYRADSAGMLVSAHMMDPIPAPSQRRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPV-- 297 IP AFDAVIARGMAK PEDRY + GDL+ AA AL+ DQDRA ILRRSQ A LP Sbjct 241 DIPKAFDAVIARGMAKRPEDRYASAGDLALAAKQALSHPDQDRAATILRRSQEAALPTAV 300 Query 298 ---------PSTHPVSPG------------------TRWPQPTPWAGGAPPWGPPSSPLP 330 P P P W P P A PWG P P Sbjct 301 NPDPRLSTAPPPRPYQPAFNTPPPSPSAAPYYQGASANWGGPPPQFANATPWG---QPPP 357 Query 331 RSARQPWLWVGVAVAVVVALAGGLGIAL 358 R R WL V V V L GLGI L Sbjct 358 RPRRNVWLIVAAVAVVFVLLGSGLGIWL 385 >gi|183984142|ref|YP_001852433.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] gi|183177468|gb|ACC42578.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] Length=667 Score = 412 bits (1059), Expect = 8e-113, Method: Compositional matrix adjust. Identities = 211/296 (72%), Positives = 237/296 (81%), Gaps = 1/296 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M SR G+ FGPYRL RL+GRGGMG+VYEAE TV+E VA+KLMSET S DPVFR R Sbjct 1 MSDAQGSRVGSTFGPYRLTRLLGRGGMGEVYEAEHTVKEWTVAVKLMSETFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR GRLQEPHVVPIHD+GEIDGQ+Y++MRLI G DL +L+R GPL PPRAVAI+ Sbjct 61 MKREARITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDNLLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Q+ SALDAAHAAG HRDVKP+NILV+ +DFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQVASALDAAHAAGVMHRDVKPQNILVTREDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVL+ECLTGSPPY+ D S++ AH+ IP+PSTVR Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGSPPYRADSASMLVTAHMMDPIPQPSTVRA 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL 295 GIP AFD VIARGMAK P DRY + GDL+ AAH AL+ DQD A DILRRSQ A L Sbjct 241 GIPKAFDTVIARGMAKQPGDRYASAGDLALAAHEALSNPDQDHAADILRRSQEATL 296 >gi|41408602|ref|NP_961438.1| hypothetical protein MAP2504 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396960|gb|AAS04821.1| hypothetical protein MAP_2504 [Mycobacterium avium subsp. paratuberculosis K-10] Length=401 Score = 410 bits (1055), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 213/321 (67%), Positives = 249/321 (78%), Gaps = 1/321 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M S+ G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KL++E+ SSDPVFR R Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVP+HD+GEIDGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHAAG HRDVKP+NILV+ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS++ TYRADIYAL CVL+ECLTGS PY+ D V+ AH+ IP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 G+P AFDAVIARGMAK PEDRY + GDL+ AA AL+T DQDRA ILRRSQ A LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPPRG 300 Query 300 THPVSPGTRWPQPTPWAGGAP 320 + P W P G+P Sbjct 301 SATPGPARCWRHRLPSTPGSP 321 >gi|120405645|ref|YP_955474.1| protein kinase [Mycobacterium vanbaalenii PYR-1] gi|119958463|gb|ABM15468.1| protein kinase [Mycobacterium vanbaalenii PYR-1] Length=574 Score = 405 bits (1042), Expect = 8e-111, Method: Compositional matrix adjust. Identities = 193/290 (67%), Positives = 232/290 (80%), Gaps = 1/290 (0%) Query 7 SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREAR 66 SR G+Q GPYRLRRL+G+GGMG+VYEAEDTV++R+VALKL+ E +S DPVFR R+QREA Sbjct 8 SRVGSQVGPYRLRRLLGKGGMGEVYEAEDTVKDRVVALKLLPEAVSHDPVFRKRLQREAH 67 Query 67 TAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSA 126 AGRLQEPHVVPIHD+GE+DG L+VDMRLI+G DL +L+ QGP+ P RA AIV Q+ SA Sbjct 68 AAGRLQEPHVVPIHDYGEVDGLLFVDMRLIDGTDLRKLLKEQGPMTPARATAIVAQVASA 127 Query 127 LDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPER 186 LDAAH G HRDVKPENIL++ DDFAYLVDFGIA+A TDE LT+LG VGT YMAPER Sbjct 128 LDAAHQNGIMHRDVKPENILINRDDFAYLVDFGIANAVTDEALTELGTAVGTYAYMAPER 187 Query 187 FSESHATYRADIYALTCVLYECLTGSPPYQGDQLS-VMGAHINQAIPRPSTVRPGIPVAF 245 F+ T+RAD+YALTCVL+ECLTG+ P+QGD +S V+ AH+N PRPS RPGIP Sbjct 188 FTNGEVTHRADVYALTCVLHECLTGAQPFQGDSVSVVITAHLNDPAPRPSQSRPGIPAGL 247 Query 246 DAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL 295 D VI+RGMAK PEDRY + G+++ AA AAL A QD+A IL+RSQ A + Sbjct 248 DDVISRGMAKRPEDRYASAGEMARAATAALTGAQQDQADSILQRSQAATM 297 >gi|145222614|ref|YP_001133292.1| protein kinase [Mycobacterium gilvum PYR-GCK] gi|145215100|gb|ABP44504.1| protein kinase [Mycobacterium gilvum PYR-GCK] Length=561 Score = 404 bits (1037), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 194/290 (67%), Positives = 236/290 (82%), Gaps = 1/290 (0%) Query 7 SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREAR 66 SR G+Q GPYRL+RL+G+GGMG+VYEA DTV++R+VALKL+ E+ S DPVFR R+QREA Sbjct 8 SRVGSQVGPYRLQRLLGKGGMGEVYEAYDTVKDRVVALKLLPESASHDPVFRKRLQREAH 67 Query 67 TAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSA 126 AGRLQEPHVVPIHD+GEIDG L+VDMR+I+GVDL +L+ QG ++P RA AIVRQI SA Sbjct 68 AAGRLQEPHVVPIHDYGEIDGLLFVDMRMIDGVDLRRILKEQGAMSPARATAIVRQIASA 127 Query 127 LDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPER 186 LDAAH AG HRDVKPENILV+ DDFAYLVDFGIA+A TDE LT+LG VGT YMAPER Sbjct 128 LDAAHRAGIMHRDVKPENILVTRDDFAYLVDFGIANAATDESLTELGTAVGTYAYMAPER 187 Query 187 FSESHATYRADIYALTCVLYECLTGSPPYQGDQLS-VMGAHINQAIPRPSTVRPGIPVAF 245 F+ T+RAD+YALTCVL+ECLTG+ P++GD +S V+ AH+NQ PRPS++R GIP Sbjct 188 FAAGEVTHRADVYALTCVLHECLTGTQPFEGDSVSVVITAHLNQPAPRPSSLRQGIPAGL 247 Query 246 DAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL 295 D VIARGMAK PEDR+ + G+L+ AA AL A+QD+A IL+RSQ A + Sbjct 248 DEVIARGMAKRPEDRFASAGELADAATDALTRAEQDQAASILQRSQAATM 297 >gi|240173401|ref|ZP_04752059.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium kansasii ATCC 12478] Length=592 Score = 403 bits (1036), Expect = 4e-110, Method: Compositional matrix adjust. Identities = 206/297 (70%), Positives = 234/297 (79%), Gaps = 1/297 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE+TV+E A+KLM+ S DPVFR R Sbjct 1 MGEAPDSRVGSMFGPYHLKRLLGRGGMGEVYEAENTVKEWPCAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REARTAGRLQEPHVVPIHD+GEIDGQ+Y++MRLI G DL +L+R GPL PPRAVAI+ Sbjct 61 MKREARTAGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDTLLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Q+ SALDAAHAAG HRDVKP N+LV+ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 SQVASALDAAHAAGVMHRDVKPPNVLVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERFS TYRADIYAL CVLYECLTGSPPY+ D S + AH+ +P+ S VR Sbjct 181 YMAPERFSNDEVTYRADIYALACVLYECLTGSPPYRADSASTLVTAHLMDPVPQASAVRS 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP 296 GIP DAVIARGMAK PEDRY + GD + AAH AL+ DQD A DILRRSQ A LP Sbjct 241 GIPKGLDAVIARGMAKRPEDRYASAGDFARAAHDALSDPDQDHAADILRRSQEATLP 297 >gi|315443079|ref|YP_004075958.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] gi|315261382|gb|ADT98123.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] Length=561 Score = 400 bits (1029), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 193/290 (67%), Positives = 235/290 (82%), Gaps = 1/290 (0%) Query 7 SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREAR 66 SR G+Q GPYRL+RL+G+GGMG+VYEA DTV++R+VALKL+ E+ S DPVFR R+QREA Sbjct 8 SRVGSQVGPYRLQRLLGKGGMGEVYEAYDTVKDRVVALKLLPESASHDPVFRKRLQREAH 67 Query 67 TAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSA 126 AGRLQEPHVVPIHD+GEI+G L+VDMR+I+GVDL +L+ QG + P RA AIVRQI SA Sbjct 68 AAGRLQEPHVVPIHDYGEIEGLLFVDMRMIDGVDLRRILKEQGAMPPARATAIVRQIASA 127 Query 127 LDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPER 186 LDAAH AG HRDVKPENILV+ DDFAYLVDFGIA+A TDE LT+LG VGT YMAPER Sbjct 128 LDAAHRAGIMHRDVKPENILVTRDDFAYLVDFGIANAATDESLTELGTAVGTYAYMAPER 187 Query 187 FSESHATYRADIYALTCVLYECLTGSPPYQGDQLS-VMGAHINQAIPRPSTVRPGIPVAF 245 F+ T+RAD+YALTCVL+ECLTG+ P++GD +S V+ AH+NQ PRPS++R GIP Sbjct 188 FAAGEVTHRADVYALTCVLHECLTGTQPFEGDSVSVVITAHLNQPAPRPSSLRQGIPAGL 247 Query 246 DAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKL 295 D VIARGMAK PEDR+ + G+L+ AA AL A+QD+A IL+RSQ A + Sbjct 248 DEVIARGMAKRPEDRFASAGELADAATDALTRAEQDQAASILQRSQAATM 297 >gi|240171192|ref|ZP_04749851.1| transmembrane serine/threonine-protein kinase H PknH_2 [Mycobacterium kansasii ATCC 12478] Length=585 Score = 399 bits (1024), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 202/285 (71%), Positives = 235/285 (83%), Gaps = 1/285 (0%) Query 10 GTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREARTAG 69 GT+FGPY L+RL+G GGMG+VYEA DTVR+R+VALKLMSE+LS DPVFR RMQREAR AG Sbjct 2 GTRFGPYYLKRLLGTGGMGEVYEAVDTVRQRVVALKLMSESLSHDPVFRMRMQREARNAG 61 Query 70 RLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSALDA 129 RLQEPHVVPIHD+GEIDGQLY+DMRLI G LA +L R GP+ PP AVA+V Q+ +ALDA Sbjct 62 RLQEPHVVPIHDYGEIDGQLYLDMRLIEGTHLALLLERFGPVTPPWAVALVHQVAAALDA 121 Query 130 AHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPERFSE 189 AHAAG HRDVKPENILV+ DDF YLVDFGIASA TDEKLTQLG+ VGT YMAPERFS+ Sbjct 122 AHAAGVMHRDVKPENILVTRDDFVYLVDFGIASAATDEKLTQLGSAVGTWRYMAPERFSD 181 Query 190 SHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRPGIPVAFDAV 248 + T+RADIY+LTCVL+ECLTG+PPY+ D ++ AH+ IPRPS +RPGIP AFDAV Sbjct 182 AEVTHRADIYSLTCVLHECLTGTPPYRADSAGMLITAHLMAPIPRPSQLRPGIPAAFDAV 241 Query 249 IARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVA 293 IARGMAK PEDRY + GDL+ AAH AL+ Q + IL+RS+ A Sbjct 242 IARGMAKRPEDRYASAGDLALAAHQALSGPHQAQEFRILKRSEEA 286 >gi|183984140|ref|YP_001852431.1| transmembrane serine/threonine-protein kinase H, PknH_1 [Mycobacterium marinum M] gi|183177466|gb|ACC42576.1| transmembrane serine/threonine-protein kinase H, PknH_1 [Mycobacterium marinum M] Length=617 Score = 399 bits (1024), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 195/297 (66%), Positives = 230/297 (78%), Gaps = 1/297 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +R G+ FGPYRL R +GRGGMG VYEAE TV+ VA+KLMSET SSDPVFR R Sbjct 1 MSEAPSARAGSMFGPYRLIRPLGRGGMGQVYEAEHTVKGWAVAVKLMSETFSSDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR GRLQEPHVVPIHD+GEIDGQ++++MRLI G +L ++L+R GPL PPRAVAI+ Sbjct 61 MKREARITGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTNLDSLLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA HRDVKP NIL++ DDFAYLVDFGIA+A TDEKLTQ+G VGT Sbjct 121 TQIASALDAAHADEVMHRDVKPPNILITRDDFAYLVDFGIANAATDEKLTQMGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLSVM-GAHINQAIPRPSTVRP 239 YMAPERF+ T+ ADIYAL CVL+E LTGS PYQ + ++ AH+ + IP+PS V P Sbjct 181 YMAPERFTNDRVTHHADIYALACVLHESLTGSAPYQSNNAGLLISAHMMEPIPKPSAVHP 240 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLP 296 IP AFDAVIARGMAK P DRY + GDL+ AAH AL+T DQ++A ILRRSQ + LP Sbjct 241 EIPKAFDAVIARGMAKKPADRYASAGDLARAAHQALSTPDQNQAETILRRSQQSTLP 297 >gi|289446860|ref|ZP_06436604.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] gi|289419818|gb|EFD17019.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] Length=300 Score = 393 bits (1009), Expect = 5e-107, Method: Compositional matrix adjust. Identities = 193/299 (65%), Positives = 230/299 (77%), Gaps = 2/299 (0%) Query 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 RQIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 QI SALDAAHA G HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 YMAPERFS TYRA LTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSNDEVTYRA-TSTRWLRAARMLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 239 Query 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVP 298 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP P Sbjct 240 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 298 >gi|183982458|ref|YP_001850749.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] gi|183175784|gb|ACC40894.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] Length=560 Score = 384 bits (987), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 220/367 (60%), Positives = 261/367 (72%), Gaps = 21/367 (5%) Query 2 DGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRM 61 D SR GTQFGPYRLRRL+GRGGMG+VYEA DTV++R VALKLMS+ +SD FR RM Sbjct 3 DTVPTSRVGTQFGPYRLRRLLGRGGMGEVYEAHDTVKDRTVALKLMSQQFNSDSTFRRRM 62 Query 62 QREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR 121 QREA TAGRLQEPH+VPIHDFGEIDGQL++DMR I G DL ++L+R G L PRAVAIV Sbjct 63 QREAHTAGRLQEPHIVPIHDFGEIDGQLFIDMRFIEGTDLGSVLKR-GALPAPRAVAIVS 121 Query 122 QIGSALDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYY 181 Q+ ALDAAH G HRD+KPENIL++ +DFAYLVDFGIA+A TD+ LT+ G VG+ Y Sbjct 122 QVAEALDAAHRGGVVHRDIKPENILITGNDFAYLVDFGIAAAATDQHLTKTGTAVGSWSY 181 Query 182 MAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQLS-VMGAHINQAIPRPSTVRPG 240 MAPERF + TYR+DIYAL CVLYECLTG+PPYQ LS +MGAH+ Q IPRPS RP Sbjct 182 MAPERFGDDEVTYRSDIYALACVLYECLTGTPPYQTQNLSTLMGAHLMQPIPRPSRHRPD 241 Query 241 IPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPST 300 IP AFD VIARGMAK+P RY T G+L+ AA AL+ DQ+RA ++ + +L P + Sbjct 242 IPTAFDEVIARGMAKDPALRYPTAGELARAARQALSAGDQERAATLIAGTH--QLAAPPS 299 Query 301 HPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQPWLWVGVAVAVVVALAGGLGIALAH 360 P+ PWA PPW P+ R R PWL + VAV VVV + G GI LA Sbjct 300 GPM----------PWA--PPPWTSPA----RRTRTPWL-LAVAVLVVVIVVVGTGIFLAR 342 Query 361 PWRSSGP 367 +SGP Sbjct 343 KEPASGP 349 >gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] gi|183177872|gb|ACC42982.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] Length=698 Score = 382 bits (982), Expect = 7e-104, Method: Compositional matrix adjust. Identities = 189/303 (63%), Positives = 230/303 (76%), Gaps = 2/303 (0%) Query 7 SREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTRMQREAR 66 SR G++FGPY L RL+GRGGMG+VYEAEDT + R+VALKL+S S +P FR RMQREA Sbjct 8 SRVGSRFGPYELVRLIGRGGMGEVYEAEDTRKRRVVALKLISTQYSGNPTFRARMQREAD 67 Query 67 TAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVRQIGSA 126 TAGRL EPH+VPIHD+GEID Q +V+MRLI+GV L AML + GPL P RAVAIVRQI +A Sbjct 68 TAGRLTEPHIVPIHDYGEIDDQFFVEMRLIDGVSLRAMLTQFGPLTPARAVAIVRQIAAA 127 Query 127 LDAAHAAGATHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLYYMAPER 186 LDAAH+ G THRDVKPENILV+ +DFAYLVDFGIA A D LTQ G VGT YMAPER Sbjct 128 LDAAHSNGVTHRDVKPENILVADNDFAYLVDFGIARAAADPGLTQGGMAVGTYNYMAPER 187 Query 187 FSESHATYRADIYALTCVLYECLTGSPPYQGDQLS-VMGAHINQAIPRPSTVRPG-IPVA 244 F+ + TYRADIYAL CVL ECLTG+PPY+ D + ++ AH+ + PRPS +RPG +P A Sbjct 188 FTGNDVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMEPPPRPSQLRPGRVPAA 247 Query 245 FDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPSTHPVS 304 D VIA+GMAKNP++RY++ GDL+ AAH AL T +Q + ILR+ L P+ P + Sbjct 248 LDEVIAKGMAKNPDERYMSAGDLAIAAHEALTTPEQRQEATILRQGDNMALMTPAVDPGA 307 Query 305 PGT 307 G+ Sbjct 308 GGS 310 Lambda K H 0.318 0.133 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1267874455038 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40