BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1776c
Length=186
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608914|ref|NP_216292.1| transcriptional regulatory protein ... 370 8e-101
gi|340626788|ref|YP_004745240.1| putative transcriptional regula... 364 4e-99
gi|339294717|gb|AEJ46828.1| transcriptional regulatory protein [... 353 5e-96
gi|183982661|ref|YP_001850952.1| transcriptional regulatory prot... 265 2e-69
gi|118618501|ref|YP_906833.1| transcriptional regulatory protein... 264 3e-69
gi|240172002|ref|ZP_04750661.1| transcriptional regulatory prote... 254 6e-66
gi|289761927|ref|ZP_06521305.1| hypothetical transcriptional reg... 253 1e-65
gi|183982663|ref|YP_001850954.1| transcriptional regulatory prot... 205 3e-51
gi|108800389|ref|YP_640586.1| TetR family transcriptional regula... 192 2e-47
gi|126436012|ref|YP_001071703.1| TetR family transcriptional reg... 188 3e-46
gi|118467465|ref|YP_885085.1| transcriptional regulatory protein... 183 8e-45
gi|333989587|ref|YP_004522201.1| transcriptional regulator [Myco... 174 4e-42
gi|296169828|ref|ZP_06851442.1| TetR family transcriptional regu... 173 9e-42
gi|254821354|ref|ZP_05226355.1| transcriptional regulator, TetR ... 173 1e-41
gi|120404739|ref|YP_954568.1| TetR family transcriptional regula... 172 2e-41
gi|145224059|ref|YP_001134737.1| TetR family transcriptional reg... 169 1e-40
gi|342860273|ref|ZP_08716925.1| hypothetical protein MCOL_15390 ... 165 3e-39
gi|336462082|gb|EGO40924.1| transcriptional regulator, tetR fami... 148 4e-34
gi|41406106|ref|NP_958942.1| hypothetical protein MAP0008c [Myco... 147 5e-34
gi|197209606|gb|ACH48045.1| probable regulatory protein [Mycobac... 146 1e-33
gi|118466504|ref|YP_879311.1| TetR family transcriptional regula... 146 1e-33
gi|229488893|ref|ZP_04382759.1| putative transcriptional regulat... 139 2e-31
gi|325674834|ref|ZP_08154521.1| TetR family transcriptional regu... 133 1e-29
gi|169629026|ref|YP_001702675.1| TetR family transcriptional reg... 131 4e-29
gi|226308419|ref|YP_002768379.1| TetR family transcriptional reg... 125 2e-27
gi|262202610|ref|YP_003273818.1| TetR family transcriptional reg... 108 5e-22
gi|343926652|ref|ZP_08766150.1| putative TetR family transcripti... 105 3e-21
gi|226361809|ref|YP_002779587.1| hypothetical protein ROP_23950 ... 99.4 2e-19
gi|254819465|ref|ZP_05224466.1| transcriptional regulator, TetR ... 91.7 5e-17
gi|342862132|ref|ZP_08718775.1| TetR family transcriptional regu... 85.9 3e-15
gi|240172895|ref|ZP_04751554.1| putative transcriptional regulat... 85.5 4e-15
gi|312138259|ref|YP_004005595.1| hypothetical protein REQ_07950 ... 84.7 6e-15
gi|41408617|ref|NP_961453.1| hypothetical protein MAP2519 [Mycob... 82.8 2e-14
gi|333918654|ref|YP_004492235.1| putative TetR family transcript... 81.6 4e-14
gi|226304633|ref|YP_002764591.1| TetR family transcriptional reg... 80.9 9e-14
gi|229494574|ref|ZP_04388337.1| transcriptional regulator, TetR ... 79.0 3e-13
gi|296179475|gb|ADG96481.1| TetR transcriptional regulator [Gord... 78.6 4e-13
gi|262200983|ref|YP_003272191.1| TetR family transcriptional reg... 77.0 1e-12
gi|111022683|ref|YP_705655.1| transcriptional regulator [Rhodoco... 76.6 1e-12
gi|296170157|ref|ZP_06851754.1| TetR family transcriptional regu... 76.6 2e-12
gi|118619595|ref|YP_907927.1| transcriptional regulatory protein... 75.1 4e-12
gi|240172648|ref|ZP_04751307.1| transcriptional regulatory prote... 75.1 5e-12
gi|296141453|ref|YP_003648696.1| TetR family transcriptional reg... 72.8 2e-11
gi|289749798|ref|ZP_06509176.1| transcriptional regulator [Mycob... 72.8 2e-11
gi|253799700|ref|YP_003032701.1| transcriptional regulator [Myco... 72.0 4e-11
gi|15608395|ref|NP_215771.1| transcriptional regulatory protein ... 71.6 4e-11
gi|226365192|ref|YP_002782975.1| TetR family transcriptional reg... 71.6 5e-11
gi|326329199|ref|ZP_08195526.1| transcriptional regulator, TetR ... 71.2 6e-11
gi|289446846|ref|ZP_06436590.1| transcriptional regulator [Mycob... 70.5 1e-10
gi|120405418|ref|YP_955247.1| TetR family transcriptional regula... 67.4 1e-09
>gi|15608914|ref|NP_216292.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15841245|ref|NP_336282.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31792965|ref|NP_855458.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97]
74 more sequence titles
Length=186
Score = 370 bits (949), Expect = 8e-101, Method: Compositional matrix adjust.
Identities = 185/186 (99%), Positives = 186/186 (100%), Gaps = 0/186 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+PGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA
Sbjct 1 MPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG
Sbjct 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP
Sbjct 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
Query 181 AFAEQS 186
AFAEQS
Sbjct 181 AFAEQS 186
>gi|340626788|ref|YP_004745240.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
gi|340004978|emb|CCC44126.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
Length=186
Score = 364 bits (934), Expect = 4e-99, Method: Compositional matrix adjust.
Identities = 182/186 (98%), Positives = 185/186 (99%), Gaps = 0/186 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+PGNDWIVGGNRRTIAAERIYAAATDLITR+GLNALDIDKLAREVHCSRATIYR AGGKA
Sbjct 1 MPGNDWIVGGNRRTIAAERIYAAATDLITRHGLNALDIDKLAREVHCSRATIYRLAGGKA 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
QIR+VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG
Sbjct 61 QIRNVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP
Sbjct 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
Query 181 AFAEQS 186
AFAEQS
Sbjct 181 AFAEQS 186
>gi|339294717|gb|AEJ46828.1| transcriptional regulatory protein [Mycobacterium tuberculosis
CCDC5079]
gi|339298346|gb|AEJ50456.1| transcriptional regulatory protein [Mycobacterium tuberculosis
CCDC5180]
Length=179
Score = 353 bits (907), Expect = 5e-96, Method: Compositional matrix adjust.
Identities = 178/179 (99%), Positives = 179/179 (100%), Gaps = 0/179 (0%)
Query 8 VGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVL 67
+GGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVL
Sbjct 1 MGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVL 60
Query 68 TRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTE 127
TRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTE
Sbjct 61 TRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTE 120
Query 128 SPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFAEQS 186
SPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFAEQS
Sbjct 121 SPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFAEQS 179
>gi|183982661|ref|YP_001850952.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183175987|gb|ACC41097.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=184
Score = 265 bits (678), Expect = 2e-69, Method: Compositional matrix adjust.
Identities = 128/184 (70%), Positives = 153/184 (84%), Gaps = 0/184 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+P +DW+VGG+RR AA+RIY AATDLI G+N LDID+LA VHCSRAT+YR GGK
Sbjct 1 MPNDDWLVGGDRRRAAADRIYDAATDLIAHEGINQLDIDRLATLVHCSRATVYRYVGGKN 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
IR+VV+ RAAARIAD VRS VE L GRERVVAAI+LS+QRIR+DPLG+LM SIHGG
Sbjct 61 DIRNVVVKRAAARIADSVRSAVENLSGRERVVAAIILSVQRIRADPLGQLMISSIHGGTQ 120
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
E+AWL +SPLLA A++LTG+AGGDP AKWVVR+VLSLMYWPAE+++ ER +VEK+VAP
Sbjct 121 EVAWLADSPLLAGVASDLTGLAGGDPHAAKWVVRIVLSLMYWPAESEDVERLMVEKFVAP 180
Query 181 AFAE 184
FAE
Sbjct 181 VFAE 184
>gi|118618501|ref|YP_906833.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|118570611|gb|ABL05362.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=184
Score = 264 bits (675), Expect = 3e-69, Method: Compositional matrix adjust.
Identities = 128/184 (70%), Positives = 153/184 (84%), Gaps = 0/184 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+P +DW+VGG+RR AA+RIY AATDLI G+N LDID+LA VHCSRAT+YR GGK
Sbjct 1 MPNDDWLVGGDRRRAAADRIYDAATDLIAHEGINQLDIDRLATLVHCSRATVYRYVGGKN 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
IR+VV+ RAAARIAD VRS VE L GRERVVAAI+LS+QRIR+DPLG+LM SIHGG
Sbjct 61 DIRNVVVKRAAARIADSVRSAVENLSGRERVVAAIILSVQRIRADPLGQLMISSIHGGTQ 120
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
E+AWL +SPLLA A++LTG+AGGDP A+WVVRVVLSLMYWPAE+++ ER +VEK+VAP
Sbjct 121 EVAWLADSPLLAGVASDLTGLAGGDPHAARWVVRVVLSLMYWPAESEDVERLMVEKFVAP 180
Query 181 AFAE 184
FAE
Sbjct 181 VFAE 184
>gi|240172002|ref|ZP_04750661.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=186
Score = 254 bits (648), Expect = 6e-66, Method: Compositional matrix adjust.
Identities = 123/186 (67%), Positives = 151/186 (82%), Gaps = 0/186 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+P +DW++GG+RR AAERIY AATDLI R GLNALDIDKLA VHCSRATIYR GGK
Sbjct 1 MPVDDWLLGGDRREAAAERIYEAATDLIARDGLNALDIDKLAIRVHCSRATIYRYVGGKT 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
+IR+ V+ R A RI D VR+ VE L G ER+V AI+L++++IR+DPL +LM GSI GG
Sbjct 61 EIRNAVVRRTAHRIVDSVRTAVEPLSGVERLVTAIMLTIKQIRADPLCQLMVGSIRGGTR 120
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
++AWL ESPL A FAT+L G+AGGDPQ AKWVVRVVLSL+YWP E++EAERRLV+ +VAP
Sbjct 121 QVAWLAESPLTAQFATDLAGLAGGDPQAAKWVVRVVLSLVYWPGEDEEAERRLVQNFVAP 180
Query 181 AFAEQS 186
AFA+ +
Sbjct 181 AFAQHN 186
>gi|289761927|ref|ZP_06521305.1| hypothetical transcriptional regulatory protein [Mycobacterium
tuberculosis GM 1503]
gi|289709433|gb|EFD73449.1| hypothetical transcriptional regulatory protein [Mycobacterium
tuberculosis GM 1503]
Length=132
Score = 253 bits (645), Expect = 1e-65, Method: Compositional matrix adjust.
Identities = 127/128 (99%), Positives = 127/128 (99%), Gaps = 0/128 (0%)
Query 59 KAQIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG 118
K QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG
Sbjct 5 KPQIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG 64
Query 119 AGELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
AGELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV
Sbjct 65 AGELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 124
Query 179 APAFAEQS 186
APAFAEQS
Sbjct 125 APAFAEQS 132
>gi|183982663|ref|YP_001850954.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183175989|gb|ACC41099.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=199
Score = 205 bits (521), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 104/186 (56%), Positives = 132/186 (71%), Gaps = 1/186 (0%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+ G +WIVG +R +AAE IY AA +LI GL+A DIDKLA VHCSRATIYR AGGKA
Sbjct 1 MAGKNWIVG-DRSAVAAELIYDAAAELIASDGLSAFDIDKLAARVHCSRATIYRYAGGKA 59
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
+IRDVV+ RAAARI + VR+ E+L G ERVVA++ +L +RSDPLG+ + GS A
Sbjct 60 KIRDVVIARAAARIVESVRAQAESLTGAERVVASVEFALAGVRSDPLGRHLVGSFPKSAN 119
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
W S L+A+FA +L GI GGD Q W+VRVVLSL+ WPAE+ E ER+LV +++ P
Sbjct 120 GAEWFVGSKLVANFAADLAGITGGDHQAGGWLVRVVLSLILWPAEDAEIERQLVHRFIGP 179
Query 181 AFAEQS 186
AF +S
Sbjct 180 AFGHES 185
>gi|108800389|ref|YP_640586.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119869518|ref|YP_939470.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|108770808|gb|ABG09530.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119695607|gb|ABL92680.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
Length=186
Score = 192 bits (488), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 99/183 (55%), Positives = 129/183 (71%), Gaps = 2/183 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VGG+RR AAERIYA+A D++ GL+ALDID LA+ +HCSRATIYR AGGKAQIR
Sbjct 4 DDWVVGGDRRDAAAERIYASAVDVVVTEGLDALDIDALAKRLHCSRATIYRYAGGKAQIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D VL R AA + D VR V G +RVV AI ++L +RSDP+ KL+ G+ + A EL
Sbjct 64 DAVLMRLAAGVIDTVRRAVADRSGADRVVTAITVALGELRSDPMRKLLMGAPN--APELG 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
L SP+L A +L+GI G DP A+W+VRVV+SL YWP + E +L+ ++VAPAF+
Sbjct 122 ALHSSPVLGQLAADLSGITGDDPLAAQWIVRVVVSLAYWPDPDPRQEEQLLRRFVAPAFS 181
Query 184 EQS 186
S
Sbjct 182 AAS 184
>gi|126436012|ref|YP_001071703.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|126235812|gb|ABN99212.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=186
Score = 188 bits (478), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 98/183 (54%), Positives = 127/183 (70%), Gaps = 2/183 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VGG+RR AAERIYA+A D++ GL+ALDID LA+ +HCSRATIYR AGGKAQIR
Sbjct 4 DDWVVGGDRRDAAAERIYASAVDVVVTEGLDALDIDALAKRLHCSRATIYRYAGGKAQIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D VL R AA + D VR V G +RVV AI ++L +RSDP+ KL+ G+ + A EL
Sbjct 64 DAVLMRLAAGVIDTVRRAVADRSGADRVVTAITVALGELRSDPMRKLLMGAPN--APELG 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
L SP+L A +L+GI DP A+W+VRVV+SL YWP + E +L+ ++VAPAF
Sbjct 122 ALHSSPVLGQLAADLSGITEDDPLAAQWIVRVVVSLAYWPDPDPRQEEQLLRRFVAPAFG 181
Query 184 EQS 186
S
Sbjct 182 AAS 184
>gi|118467465|ref|YP_885085.1| transcriptional regulatory protein [Mycobacterium smegmatis str.
MC2 155]
gi|118168752|gb|ABK69648.1| putative transcriptional regulatory protein [Mycobacterium smegmatis
str. MC2 155]
Length=178
Score = 183 bits (465), Expect = 8e-45, Method: Compositional matrix adjust.
Identities = 107/178 (61%), Positives = 131/178 (74%), Gaps = 3/178 (1%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW++GG+RRT AAERIYAAAT+L+ R GL+A DID LA VHCSRAT+YR AGGKAQIRD
Sbjct 3 DWLLGGDRRTAAAERIYAAATELVLRDGLDAFDIDTLAARVHCSRATVYRYAGGKAQIRD 62
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAW 124
VL R AA I D VR V L GRERVV A+ ++L+ IRSDP+ ++M G G +L+
Sbjct 63 AVLLRLAASIVDSVRQAVGHLSGRERVVRAVTVALEHIRSDPIRQMMVGL--GAGRDLSE 120
Query 125 LTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
L SP+LAD A ELTG+ DPQ A+W+VRVV+SL WP + AE LVE++VAPAF
Sbjct 121 LPASPVLADLAAELTGVT-DDPQAAQWIVRVVMSLAVWPIGDAAAEAGLVERFVAPAF 177
>gi|333989587|ref|YP_004522201.1| transcriptional regulator [Mycobacterium sp. JDM601]
gi|333485555|gb|AEF34947.1| transcriptional regulatory protein [Mycobacterium sp. JDM601]
Length=191
Score = 174 bits (442), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 89/181 (50%), Positives = 122/181 (68%), Gaps = 2/181 (1%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
+DW++G +RR+ AERIYAAA +LI+R G +A ID LA VHCS ATIYR AGGKA I
Sbjct 3 AHDWLIGRDRRSEGAERIYAAAAELISRQGYDAFTIDALAAVVHCSPATIYRHAGGKAAI 62
Query 63 RDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGEL 122
RD VL R A RI D VR + L G ER+V A L++LQR+R++PL ++M ++ G G
Sbjct 63 RDTVLARQAERILDSVRDAITGLTGSERIVTATLVALQRLRAEPLSQIM-RAMTGSPGT- 120
Query 123 AWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
WLT+SP++A FA E+ G A DP A+W++R+ L+L YWP + E V +++ P +
Sbjct 121 DWLTDSPVVARFAAEMVGDANPDPLAAQWLIRMFLALWYWPIHGADDEEAAVRRFLGPPY 180
Query 183 A 183
A
Sbjct 181 A 181
>gi|296169828|ref|ZP_06851442.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295895505|gb|EFG75205.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=182
Score = 173 bits (439), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 100/183 (55%), Positives = 131/183 (72%), Gaps = 3/183 (1%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G+DW++GG+RR AA+RIYAAATDL+ R GL+A DID LA VHCSRATIYR AGGKAQI
Sbjct 3 GHDWVIGGDRRAAAADRIYAAATDLVVRDGLDAFDIDALAARVHCSRATIYRYAGGKAQI 62
Query 63 RDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGEL 122
RD VL R +A I + VR V L G +RV+ A+ ++L++IRSDPL +LM G + +L
Sbjct 63 RDAVLIRLSAGIIERVRRAVAGLSGPDRVITAVTVALEQIRSDPLRRLMLSP--GSSPDL 120
Query 123 AWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
L SP+L+ A ELTGI DP A+W+VRVVLSL YWP + ER ++E+++AP F
Sbjct 121 GELHASPVLSHLAAELTGIT-DDPDAAQWIVRVVLSLAYWPLASSRVERNVLERFLAPGF 179
Query 183 AEQ 185
++
Sbjct 180 TQR 182
>gi|254821354|ref|ZP_05226355.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=188
Score = 173 bits (438), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 91/186 (49%), Positives = 123/186 (67%), Gaps = 2/186 (1%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+P +DW+VG +RR+ AAERIY+AA DLI R G I+ LA VHCS ATIYR AGGKA
Sbjct 1 MPRDDWLVGRDRRSEAAERIYSAAADLIARRGYEGFTIEALAARVHCSPATIYRHAGGKA 60
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG 120
IRD V+ AARI D R ++ LRG +RVVAA +++L+R+RSDPL +LM SIH A
Sbjct 61 TIRDAVVAIHAARIVDTTREAIKDLRGPDRVVAATIIALERLRSDPLAQLM-RSIH-AAP 118
Query 121 ELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
W+ SP + A E+ G P A+W++RV L L WP ++ AER LVE+++ P
Sbjct 119 VSDWVISSPTVTSLAAEMLGPGNHHPLAAQWLIRVFLGLWAWPLKDPAAERALVERFLGP 178
Query 181 AFAEQS 186
++A ++
Sbjct 179 SYAPRT 184
>gi|120404739|ref|YP_954568.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119957557|gb|ABM14562.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=178
Score = 172 bits (437), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 88/175 (51%), Positives = 122/175 (70%), Gaps = 3/175 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +RR AA+RI++AATDLI R GL+ D+ L VHCSRATIYR GGKAQIR
Sbjct 3 DDWLVG-DRRAEAADRIFSAATDLIVRDGLDGFDMAALQAAVHCSRATIYRHVGGKAQIR 61
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
+ VL R A RI VRS V L G ER V A++++L+RIR+DP+G+ + ++ EL
Sbjct 62 EAVLLRQAERIIATVRSAVVGLSGAERTVTAVVVALERIRADPIGQTLLSAMRK--DELT 119
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
W+ S + A ELTGI DPQ A+W+VRVVL+L++WP E+ AER ++++++
Sbjct 120 WIGRSAVPPALAAELTGIDDDDPQAAQWIVRVVLALLFWPVEDPAAEREMLQRFL 174
>gi|145224059|ref|YP_001134737.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|315444395|ref|YP_004077274.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
gi|145216545|gb|ABP45949.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
gi|315262698|gb|ADT99439.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=197
Score = 169 bits (429), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 86/179 (49%), Positives = 118/179 (66%), Gaps = 2/179 (1%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW++G +RR+ AERIY AA DL+ R G + ID LA VHCS ATIYR GGK+ IRD
Sbjct 15 DWLIGRDRRSEGAERIYVAAADLMARRGYDGFGIDALAAAVHCSPATIYRHVGGKSAIRD 74
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAW 124
VVL R A + D VR + L G ER+V A L++LQR+R+ PL ++M S+ G G W
Sbjct 75 VVLERQAEHVLDSVRQAIAGLEGSERIVTATLVALQRMRAAPLAEVMR-SMPGPPGT-GW 132
Query 125 LTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
L +SP++A A E+ G A DP A+W++RV L+L YWP ++EAE+ V +++ P +A
Sbjct 133 LIDSPVVARLAAEMVGTADADPLAAQWLIRVFLALWYWPMHDEEAEKAAVLRFLGPPYA 191
>gi|342860273|ref|ZP_08716925.1| hypothetical protein MCOL_15390 [Mycobacterium colombiense CECT
3035]
gi|342132651|gb|EGT85880.1| hypothetical protein MCOL_15390 [Mycobacterium colombiense CECT
3035]
Length=188
Score = 165 bits (417), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 87/179 (49%), Positives = 118/179 (66%), Gaps = 2/179 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +R + A ERIY+AA DLI R+G + I+ LA VHCS ATIYR AGGKA IR
Sbjct 4 DDWLVGRDRGSEATERIYSAAADLIARHGYDGFTIEALAARVHCSPATIYRHAGGKATIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D V+ AARI D R ++ L GRERVV A +++L+R+RSDPL +LM SIH A
Sbjct 64 DAVIRMQAARIIDKTREAIKDLTGRERVVTATIMALERLRSDPLAQLMR-SIH-AAPVSD 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
W+ SP + A E+ G DP A+W++RV L+L WP ++ AER LVE+++ ++
Sbjct 122 WVINSPAVTALAAEMLGPGNDDPLAAQWLIRVFLALWGWPLKDPAAERALVERFLGSSY 180
>gi|336462082|gb|EGO40924.1| transcriptional regulator, tetR family [Mycobacterium avium subsp.
paratuberculosis S397]
Length=192
Score = 148 bits (373), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 89/181 (50%), Positives = 119/181 (66%), Gaps = 2/181 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +RR+ AAERIYAAA DLI R G + I+ LA VHCS ATIYR AGGKA IR
Sbjct 4 DDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEALAARVHCSPATIYRHAGGKATIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D V+ AARI D R ++ LRG ERVV A +++L+R+RSDPL +LM SIH A
Sbjct 64 DAVVGIQAARIVDTTREAIKDLRGPERVVTATIMALERLRSDPLAQLMR-SIH-AAPVSD 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
W+ SP + A E+ G DP A+W++RV L+L WP ++ AER LV +++ ++
Sbjct 122 WVINSPTVTALAAEMLGPGHDDPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASYR 181
Query 184 E 184
+
Sbjct 182 Q 182
>gi|41406106|ref|NP_958942.1| hypothetical protein MAP0008c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41394454|gb|AAS02325.1| hypothetical protein MAP_0008c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=192
Score = 147 bits (372), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 89/179 (50%), Positives = 118/179 (66%), Gaps = 2/179 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +RR+ AAERIYAAA DLI R G + I+ LA VHCS ATIYR AGGKA IR
Sbjct 4 DDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEALAARVHCSPATIYRHAGGKATIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D V+ AARI D R ++ LRG ERVV A +++L+R+RSDPL +LM SIH A
Sbjct 64 DAVVGIQAARIVDTTREAIKDLRGPERVVTATIMALERLRSDPLAQLMR-SIH-AAPVSD 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
W+ SP + A E+ G DP A+W++RV L+L WP ++ AER LV +++ ++
Sbjct 122 WVINSPTVTALAAEMLGPGHDDPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASY 180
>gi|197209606|gb|ACH48045.1| probable regulatory protein [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=207
Score = 146 bits (369), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 88/181 (49%), Positives = 118/181 (66%), Gaps = 2/181 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +RR+ AAERIYAAA DLI R G + I+ LA VHC ATIYR AGGKA IR
Sbjct 4 DDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEALAARVHCPPATIYRHAGGKATIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D V+ AARI D R ++ LRG ERVV A +++L+R+RSDPL +LM SIH A
Sbjct 64 DAVVGIQAARIVDTTREAIKDLRGPERVVTATIMALERLRSDPLAQLM-RSIH-AAPVSD 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
W+ SP + A E+ G DP A+W++RV L+L WP ++ AER LV +++ ++
Sbjct 122 WVINSPTVTALAAEMLGPGHDDPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASYR 181
Query 184 E 184
+
Sbjct 182 Q 182
>gi|118466504|ref|YP_879311.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|254773061|ref|ZP_05214577.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
gi|118167791|gb|ABK68688.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=192
Score = 146 bits (368), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 88/179 (50%), Positives = 118/179 (66%), Gaps = 2/179 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+VG +RR+ AAERIYAAA DLI R G + I+ LA VHCS ATIYR AGGKA IR
Sbjct 4 DDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEALAARVHCSPATIYRHAGGKATIR 63
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
D V+ AARI D R ++ LRG ERVV A +++L+R+RSDPL +LM SIH A
Sbjct 64 DAVVGIQAARIVDTTREAIKDLRGPERVVTATIMALERLRSDPLAQLMR-SIH-AAPVSD 121
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
W+ SP + A E+ G +P A+W++RV L+L WP ++ AER LV +++ ++
Sbjct 122 WVINSPTVTALAAEMLGPGHDNPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASY 180
>gi|229488893|ref|ZP_04382759.1| putative transcriptional regulatory protein [Rhodococcus erythropolis
SK121]
gi|229324397|gb|EEN90152.1| putative transcriptional regulatory protein [Rhodococcus erythropolis
SK121]
Length=184
Score = 139 bits (349), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 79/178 (45%), Positives = 113/178 (64%), Gaps = 8/178 (4%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+ GGNR +A ERI+AAA +LI G + + D +A CSRAT+YR GGK+ IR+
Sbjct 11 DWLAGGNRSELATERIFAAAAELIREQGFDRFNADDVAARAGCSRATLYRYVGGKSAIRE 70
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSD-PLGKLMFGSIHGGAGELA 123
+L+R AA +A V + VE+L G ER+V +IL+++ IRSD + + + G E
Sbjct 71 GLLSRGAASVASQVATAVESLHGDERIVESILVAVDAIRSDAAMSHGLAAARANGIDE-- 128
Query 124 WLTESPLLADFATELTGIAGGDPQG--AKWVVRVVLSLMYWPAENDEAERRLVEKYVA 179
+L SPLL A EL G+ DP+G ++WVVR+VL L+ WP + AERR+VE +V+
Sbjct 129 YLVSSPLLPRTALELAGL---DPEGQESQWVVRIVLMLLAWPLADRAAERRMVESFVS 183
>gi|325674834|ref|ZP_08154521.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
gi|325554420|gb|EGD24095.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
Length=183
Score = 133 bits (335), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 83/180 (47%), Positives = 107/180 (60%), Gaps = 2/180 (1%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
+DW+ GGNRR +A RI AAATDL G + L + +A CSRAT+YR GGK I
Sbjct 5 DDWLAGGNRREVAVARITAAATDLFLERGFDRLGVLDVAERAGCSRATLYRYVGGKPAIV 64
Query 64 DVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
V++ AAA +A+ V V L G +RVV AIL S+ +R+DP F GA
Sbjct 65 AAVVSSAAASVAEDVACAVAHLDGADRVVEAILTSVAAVRADPALSYWFAHNRTGAAN-G 123
Query 124 WLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
+L SP LA FAT LTG D G +W+VRVVL+L+ WP + + ER +V +VAPAFA
Sbjct 124 YLASSPDLARFATTLTGAVADDLAG-EWIVRVVLTLLAWPGADGDTERHMVRHFVAPAFA 182
>gi|169629026|ref|YP_001702675.1| TetR family transcriptional regulator [Mycobacterium abscessus
ATCC 19977]
gi|169240993|emb|CAM62021.1| Putative transcriptional regulator, TetR family [Mycobacterium
abscessus]
Length=214
Score = 131 bits (330), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 69/183 (38%), Positives = 105/183 (58%), Gaps = 3/183 (1%)
Query 2 PGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQ 61
P DW+ G +R TIAA+RI + A I R+GL+ L++D +ARE CSRAT+YR GGK
Sbjct 3 PYADWLHGSDRHTIAADRIVSVAAKQIARHGLDRLNLDAVAREAGCSRATVYRHVGGKTA 62
Query 62 IRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGE 121
I D VL R A++ ++ V++ R R V AI SL IR DP+ M ++
Sbjct 63 IVDAVLARNIAKVTADIQRAVQSADARRRAVVAITASLTAIRHDPVISTMIATM-SPTSL 121
Query 122 LAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPA 181
++L S + A+ TG+A D A+W+ RVV++L++WP + E ++E++V P
Sbjct 122 GSYLNASSEIPRSASAFTGLA--DETAAQWISRVVMALLFWPTSDPAQESEMIERFVYPV 179
Query 182 FAE 184
+
Sbjct 180 LKD 182
>gi|226308419|ref|YP_002768379.1| TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
gi|226187536|dbj|BAH35640.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
Length=181
Score = 125 bits (315), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 81/182 (45%), Positives = 111/182 (61%), Gaps = 16/182 (8%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+ GGNRR +A ERI+AAA +LI G D +A CSRAT+YR GGK+ IR+
Sbjct 8 DWLAGGNRRELATERIFAAAAELIREQGFVRFSADDVASRAGCSRATLYRYVGGKSAIRE 67
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA- 123
+L+R AA +A V + VE+LRG ER+V +IL+++ IR+D HG A A
Sbjct 68 GLLSRGAASVASQVAAAVESLRGDERIVESILVAVDAIRADA------AMSHGLAAARAN 121
Query 124 ----WLTESPLLADFATELTGIAGGDPQG--AKWVVRVVLSLMYWPAENDEAERRLVEKY 177
+L SPLL A EL G+ DP+G ++WVVR+VL L+ WP + ERR+VE +
Sbjct 122 GIDEYLVSSPLLPRTALELAGL---DPEGQQSQWVVRIVLMLLAWPLADRADERRMVESF 178
Query 178 VA 179
V+
Sbjct 179 VS 180
>gi|262202610|ref|YP_003273818.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262085957|gb|ACY21925.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=182
Score = 108 bits (269), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 66/174 (38%), Positives = 93/174 (54%), Gaps = 1/174 (0%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
DW+VGG R A R+ A ++ + G++ +I+ LA HCSRAT+YR GGK I
Sbjct 2 AQDWLVGGVRADSARNRLLDVAATIVAQRGIDRFEINDLAARAHCSRATVYRHVGGKQAI 61
Query 63 RDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGEL 122
+ VL A+ I D VR V +L G ER AI ++L+ IR+DP+ S G
Sbjct 62 VETVLGVASVHIVDTVREAVVSLHGPERAQVAIEVALREIRADPVTSQFIRSGRFLEGTR 121
Query 123 AWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
L SP++A A EL + D A VR VL+L+ WPA E E +++E+
Sbjct 122 LVL-HSPVVARIAAELIDLDPTDNVPAALAVRSVLALLIWPASTPELEIQMIEE 174
>gi|343926652|ref|ZP_08766150.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
gi|343763404|dbj|GAA13076.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
Length=212
Score = 105 bits (262), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 67/180 (38%), Positives = 100/180 (56%), Gaps = 6/180 (3%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+VGG+R A R+ + AT LI GL+A +D+LA HCSRATIYR AGG+AQ+ +
Sbjct 13 DWLVGGDRGDAARRRLVSQATALIASRGLDAFSVDELAVRAHCSRATIYRHAGGRAQLIE 72
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMF--GSIHGGAGEL 122
VL+ AA + + +R + G ER AI ++ +R+D + + GS+
Sbjct 73 AVLSMTAAPVLESIREEAAGTTGDERARIAITAAVGALRADRVIRQFLRPGSL---IATT 129
Query 123 AWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAF 182
+ SP + A EL GI D A++ +R VL+++ WPA +E E LV+ +A F
Sbjct 130 PTVLASPTVLAVAAELIGIDPDDAVAARFAIRSVLTMLLWPAAPEE-EAALVDSIIAGIF 188
>gi|226361809|ref|YP_002779587.1| hypothetical protein ROP_23950 [Rhodococcus opacus B4]
gi|226240294|dbj|BAH50642.1| hypothetical protein [Rhodococcus opacus B4]
Length=151
Score = 99.4 bits (246), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 58/148 (40%), Positives = 90/148 (61%), Gaps = 4/148 (2%)
Query 36 LDIDKLAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIADGVRSDVETLRGRERVVAAI 95
+D+D++A CSRAT+YR GGK + + V++RAA +A+ + + ++ ER+V AI
Sbjct 1 MDVDRVAARAGCSRATLYRYVGGKRALVEAVMSRAADAVAERIEAALQPFENAERIVEAI 60
Query 96 LLSLQRIRSDP-LGKLMFGSIHGGAGELAWLTESPLLADFATELTGIAGGDPQGAKWVVR 154
L +L IR++P L + + G+ E +L +P L A LT IA D + A W+VR
Sbjct 61 LAALVEIRAEPTLVRWLAGAHPRSTDE--YLARAPELGRVAISLTRIA-PDEEAAGWMVR 117
Query 155 VVLSLMYWPAENDEAERRLVEKYVAPAF 182
VVL+L+ WP + AER +VE++V P F
Sbjct 118 VVLALLTWPLPDPAAERHIVERFVEPVF 145
>gi|254819465|ref|ZP_05224466.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=193
Score = 91.7 bits (226), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 62/193 (33%), Positives = 105/193 (55%), Gaps = 10/193 (5%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+PGNDW+ R AA+RI AA +L T+ +++ ++++AR CSRAT+YR +
Sbjct 1 MPGNDWL-SARRSEAAADRILDAAEELYTQRDSDSIGMNEIARAAGCSRATLYRYFENRE 59
Query 61 QIRDVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGGA 119
+R + R R+ + + + ER+VA+IL++LQ +R P F +
Sbjct 60 ALRTAYVHRETHRLGRAILARTGGIEDPHERLVASILVTLQMVRESPALASWFATTRPPV 119
Query 120 -GELAWLTESPLLADFATE-LTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAERRL 173
GELA +S ++A A L + DP + A+WVVRV++S++ +P ++ ER +
Sbjct 120 GGELA--GQSDVIAALAAAFLNSLGADDPAVVERRARWVVRVIVSMLLFPGHDEADERAM 177
Query 174 VEKYVAPAFAEQS 186
+E++V P A S
Sbjct 178 IEEFVVPIVAPVS 190
>gi|342862132|ref|ZP_08718775.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342130436|gb|EGT83751.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=193
Score = 85.9 bits (211), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 61/189 (33%), Positives = 103/189 (55%), Gaps = 14/189 (7%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
+PGNDW+ G +R AA+RI AA L T+ ++ ++++AR CSRAT+YR +
Sbjct 1 MPGNDWL-GTHRTEAAADRILDAAERLYTQRDSGSIGMNEIARAAGCSRATLYRYFENRD 59
Query 61 QIRDVVLTRAAARIADGV---RSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHG 117
+R + R R+ + D+E RER+VA++L++L+ +R P F +
Sbjct 60 ALRTAYVHRETHRLGREIIARTGDIED--PRERLVASVLVTLRMVRESPALASWFATTRP 117
Query 118 G-AGELAWLTESPLLADFATE-LTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAER 171
GELA S ++A A L + DP + +W+VRV++SL+ P +++ ER
Sbjct 118 PVGGELA--GHSDVIAALAVAFLHSLGPDDPAVIERRGRWMVRVIVSLLTHPGRDEDEER 175
Query 172 RLVEKYVAP 180
++E++V P
Sbjct 176 AMIEEFVVP 184
>gi|240172895|ref|ZP_04751554.1| putative transcriptional regulatory protein [Mycobacterium kansasii
ATCC 12478]
Length=56
Score = 85.5 bits (210), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 37/55 (68%), Positives = 47/55 (86%), Gaps = 0/55 (0%)
Query 129 PLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFA 183
P L+DFA +LTG+ G DP AK++VRVV+SLMYWP E+D+AERRLV+K+VAP FA
Sbjct 2 PQLSDFARDLTGLTGDDPDDAKYLVRVVVSLMYWPGEDDDAERRLVDKFVAPMFA 56
>gi|312138259|ref|YP_004005595.1| hypothetical protein REQ_07950 [Rhodococcus equi 103S]
gi|311887598|emb|CBH46910.1| putative secreted protein [Rhodococcus equi 103S]
Length=127
Score = 84.7 bits (208), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 57/127 (45%), Positives = 74/127 (59%), Gaps = 2/127 (1%)
Query 57 GGKAQIRDVVLTRAAARIADGVRSDVETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIH 116
GGK I V++ AAA +A+ V V L G +RVV AIL S+ +R+DP F
Sbjct 2 GGKPAIVAAVVSSAAASVAEDVACAVAHLDGADRVVEAILTSVAAVRADPALSYWFAHNR 61
Query 117 GGAGELAWLTESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
GA +L SP LA FAT LTG D G +W+VRVVL+L+ WP + + ER +V
Sbjct 62 TGAAN-GYLASSPDLARFATTLTGAVADDLAG-EWIVRVVLTLLAWPGADGDTERHMVRH 119
Query 177 YVAPAFA 183
+VAPAFA
Sbjct 120 FVAPAFA 126
>gi|41408617|ref|NP_961453.1| hypothetical protein MAP2519 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|118462230|ref|YP_880645.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|254774282|ref|ZP_05215798.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
gi|41396975|gb|AAS04836.1| hypothetical protein MAP_2519 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|118163517|gb|ABK64414.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
gi|336458596|gb|EGO37563.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=197
Score = 82.8 bits (203), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 55/185 (30%), Positives = 96/185 (52%), Gaps = 10/185 (5%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
DW+ G+R A +RI AA +L T+ ++ ++++AR CSRAT+YR + +
Sbjct 7 STDWL-SGHRNEAAVDRILDAAQELYTQRDSESIGMNEIARAAGCSRATLYRYFENREAL 65
Query 63 RDVVLTRAAARIADGVRSDVETL-RGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AG 120
R + R A R+ + ++ + R+R+ A+I +L+ +R +P F AG
Sbjct 66 RTAYVHREANRLGRAIMEQIDGIDEPRQRLTASITTTLRMVRGNPALASWFAVTRPPIAG 125
Query 121 ELAWLTESPLLADFATELTGIAGGDPQG-----AKWVVRVVLSLMYWPAENDEAERRLVE 175
ELA +E ++ A G G + A+WVVRV+ SL+ +P ++ ER ++E
Sbjct 126 ELAEHSE--VITALAAAFVGSLGPEEPAVVERRARWVVRVITSLLLFPGHDEADERAMIE 183
Query 176 KYVAP 180
++V P
Sbjct 184 EFVVP 188
>gi|333918654|ref|YP_004492235.1| putative TetR family transcriptional regulator [Amycolicicoccus
subflavus DQS3-9A1]
gi|333480875|gb|AEF39435.1| Putative TetR family transcriptional regulator [Amycolicicoccus
subflavus DQS3-9A1]
Length=189
Score = 81.6 bits (200), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 65/183 (36%), Positives = 94/183 (52%), Gaps = 5/183 (2%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+ G R AAERI AA L G+ A + +A+E CSRAT+YR + +R
Sbjct 4 DWL-GAARSAHAAERILDAAARLFAERGVAATQMADIAQEAGCSRATLYRYFDNRQAVRT 62
Query 65 VVLTRAAARIADGVRSDV-ETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AGEL 122
+ R A RI V +V E ER+V L +L+ +RSDPL F SI + E+
Sbjct 63 AFVHREARRIGAVVADEVSEIADPGERLVEGTLTALRAVRSDPLLIAWFRSIDAVLSAEI 122
Query 123 AWLTESPLLADFATELTGIAGGDP--QGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAP 180
+ +E A IA + Q A+W R+++SL+ P +D ER ++EK++AP
Sbjct 123 SQTSEVIQAMAAAFLPAAIAPAEERAQLARWTTRIIVSLLTMPGRDDADERGMLEKFLAP 182
Query 181 AFA 183
A A
Sbjct 183 AVA 185
>gi|226304633|ref|YP_002764591.1| TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
gi|226183748|dbj|BAH31852.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
Length=187
Score = 80.9 bits (198), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 59/179 (33%), Positives = 90/179 (51%), Gaps = 6/179 (3%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
NDW+ G R AAE+I +A L G+NA+ + ++A CSRAT+YR + +
Sbjct 3 NDWL-GEGRALAAAEKILDSAAQLFVEKGVNAVGMAEIASAAGCSRATLYRYFENRQALH 61
Query 64 DVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AGE 121
+ R A R+ + V T+ ER+ A+L ++ +RS P F AGE
Sbjct 62 IAFVHREARRLGTAIAESVATIDDPSERLETAMLTAVSAVRSTPTLAAWFTPGDASLAGE 121
Query 122 LAWLTESPLLADFATELTG-IAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVA 179
LA S ++ + G I G A+W+VRV+LSL+ P ++ ER LV ++VA
Sbjct 122 LA--NSSDVINGLGVAMLGEIGAGTASRARWIVRVILSLLMVPGADENDERTLVREFVA 178
>gi|229494574|ref|ZP_04388337.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis
SK121]
gi|229318936|gb|EEN84794.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis
SK121]
Length=187
Score = 79.0 bits (193), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 58/178 (33%), Positives = 89/178 (50%), Gaps = 6/178 (3%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
NDW+ G R AAE+I +A L G+NA+ + ++A CSRAT+YR + +
Sbjct 3 NDWL-GEGRALAAAEKILDSAAQLFVAKGVNAVGMAEIASAAGCSRATLYRYFENRQALH 61
Query 64 DVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AGE 121
+ R A R+ + V T+ ER+ AIL ++ +RS P F AGE
Sbjct 62 IAFVHREARRLGTSIAESVATIDDPSERLETAILTAVSAVRSTPTLAAWFTPGDASLAGE 121
Query 122 LAWLTESPLLADFATELTG-IAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
LA S ++ + G + G A+W+VRV+LSL+ P ++ ER LV ++V
Sbjct 122 LA--NSSDVINGLGVAMLGELGAGTASRARWIVRVILSLLMVPGADENDERTLVREFV 177
>gi|296179475|gb|ADG96481.1| TetR transcriptional regulator [Gordonia cholesterolivorans]
Length=214
Score = 78.6 bits (192), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 64/186 (35%), Positives = 96/186 (52%), Gaps = 13/186 (6%)
Query 1 VPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKA 60
V G DW+ G RR + I A ++ G NA + +A V CSRAT+YR G+
Sbjct 26 VRGADWMRG-TRRPAVQDAILEIAGEVFATKGANA-SMGDIAAAVGCSRATLYRYFDGRR 83
Query 61 QIRDVVLTRAAARIADGVRSDVETLRGR----ERVVAAILLSLQRIRSDPLGKLMFGSIH 116
Q++ + R A RI V ET+ R +R+ +I+++L +R DP F +
Sbjct 84 QLQLAYVERVARRIGAVV---AETVSDRPEPADRLTESIIVALTEVRRDPALAAWFTAAG 140
Query 117 GG-AGELAWLTESPLLADFATELTGIAGGDP-QGAKWVVRVVLSLMYWPAENDEAERRLV 174
G AGELA +E + AT G G D + A+WVVRV++SL+ P + E ER ++
Sbjct 141 AGVAGELALSSE--FIETVATAFLGTGGEDGGEAARWVVRVIVSLLAVPEGSPERERAVI 198
Query 175 EKYVAP 180
++V P
Sbjct 199 ARFVTP 204
>gi|262200983|ref|YP_003272191.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262084330|gb|ACY20298.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=192
Score = 77.0 bits (188), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 60/185 (33%), Positives = 98/185 (53%), Gaps = 11/185 (5%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
DW+ R +A+ RI A +L T G++++ + +A+ V CSRAT+YR GK ++
Sbjct 4 TDWL-AAERADLASRRILDRAEELFTARGVSSVTMRDVAQAVGCSRATLYRYFPGKTELL 62
Query 64 DVVLTRAAARIADGVRSDVETLRGR-ERVVAAILLSLQRIRSDP-LGKLMFGSIHGGAGE 121
+ RAA +A+ + T+ ER+VAA+ +L +R +P L G A
Sbjct 63 AAYVDRAAGELAEEIARGTRTVADPAERLVAAVRTALDGVRGNPALAAWFTPETAGPATH 122
Query 122 LAWLTESPLLADFATE-LTGIAGGDPQG-----AKWVVRVVLSLMYWPAENDEAERRLVE 175
LA + SP + AT L G+A + A+W+VRV++SL+ PA + +AE L+
Sbjct 123 LALV--SPAIESIATSFLGGVAPASDETDRTERARWLVRVIVSLLSDPAGSPDAEADLLR 180
Query 176 KYVAP 180
++V P
Sbjct 181 RFVVP 185
>gi|111022683|ref|YP_705655.1| transcriptional regulator [Rhodococcus jostii RHA1]
gi|110822213|gb|ABG97497.1| possible transcriptional regulator [Rhodococcus jostii RHA1]
Length=192
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 58/187 (32%), Positives = 97/187 (52%), Gaps = 9/187 (4%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+ R +AAERI A L G+ A+ + ++AR CSRAT+YR + ++
Sbjct 4 DWM-RDERPRLAAERILDVAAQLYVENGIAAVGMAEVARAAGCSRATLYRYFDSRQSLQL 62
Query 65 VVLTRAAARIADGVRSDVETL-RGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELA 123
+ R A RI V +V ++ +V A+L +++ +R+DP F G +G A
Sbjct 63 AFVHREARRIGALVAEEVSAAGDPKDVIVEAMLAAIRLVRADPTLAAWFQ--LGDSGLAA 120
Query 124 WLTESP-LLADFATELTGIAGGD----PQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
+ S ++ + G AG + A+W+VR+++SL+ P +D ER ++E++V
Sbjct 121 QIAHSSDVIESLGSAFLGQAGFSGEETSRKARWLVRIIVSLLTVPGVDDTDERTMLEQFV 180
Query 179 APAFAEQ 185
APA AE
Sbjct 181 APALAEH 187
>gi|296170157|ref|ZP_06851754.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295895183|gb|EFG74898.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=192
Score = 76.6 bits (187), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 97/184 (53%), Gaps = 10/184 (5%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
DW+ G +R AA+RI AA L T ++ ++++AR CSRAT+YR + +R
Sbjct 3 TDWL-GAHRTEAAADRILDAAERLYTERDHASIGMNEIARAAGCSRATLYRYFENREALR 61
Query 64 DVVLTRAAARIADGVRSDVETL-RGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGAG-E 121
+ R R++ ++ ++ + RER++A+I +L+ +R F G E
Sbjct 62 TAYVHRETRRLSRAIKEEIGGIDDARERLLASITATLRMVRGSRALASWFAITRPPIGAE 121
Query 122 LAWLTESPLLADFATELTGIAGG-DP----QGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
+A +S ++ A G G DP + A+WVVRV+ SL+ +P +D ER ++E+
Sbjct 122 VA--GQSEVITALAAAFVGSLGPEDPAVVERRARWVVRVITSLLQFPGRDDADERAMIEE 179
Query 177 YVAP 180
+VAP
Sbjct 180 FVAP 183
>gi|118619595|ref|YP_907927.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|183984156|ref|YP_001852447.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|118571705|gb|ABL06456.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|183177482|gb|ACC42592.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=193
Score = 75.1 bits (183), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 52/184 (29%), Positives = 95/184 (52%), Gaps = 10/184 (5%)
Query 4 NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIR 63
DW+ +R +AA+RI AA L T + ++ ++++AR CSRAT+YR + +R
Sbjct 4 TDWL-AAHRSEVAADRILDAAERLYTEHDPASIGMNEIARAAGCSRATLYRYFESREALR 62
Query 64 DVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AGE 121
+ R R+ + + + R++++ +I +L+ +R P F S GE
Sbjct 63 TAYVHRETLRLGREIMQQIGDIDDPRDQLITSITATLRMVRQRPALAAWFASTRPPIGGE 122
Query 122 LAWLTESPLLADFATELTGIAGGDPQG-----AKWVVRVVLSLMYWPAENDEAERRLVEK 176
LA +S ++A A G + A+W VRV++SL+ +P +++ ER ++E+
Sbjct 123 LA--GQSEVIAGLAAAFLQSLGPEAPAAVERRARWTVRVIVSLLMFPGQDEADERAMLEE 180
Query 177 YVAP 180
+VAP
Sbjct 181 FVAP 184
>gi|240172648|ref|ZP_04751307.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=193
Score = 75.1 bits (183), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 54/180 (30%), Positives = 92/180 (52%), Gaps = 6/180 (3%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G DW+ R +AA+RI AA L T ++ ++++AR CSRAT+YR + +
Sbjct 3 GTDWL-AARRTEVAADRILDAAAQLYTVRDPASIGMNEIARAAGCSRATLYRYFDSREAL 61
Query 63 RDVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AG 120
R + R R+ + + + +ER+VA+I +L+ +R P F + G
Sbjct 62 RTAYVHRETRRLGREIMQQISGVEDPQERLVASIAATLRMVRESPALAAWFAATRPPIGG 121
Query 121 ELAWLTE--SPLLADFATELTGIAGGD-PQGAKWVVRVVLSLMYWPAENDEAERRLVEKY 177
ELA +E + L A F L + G + A+W VRV++SL+ +P ++ ER ++E +
Sbjct 122 ELAGQSEVIAALAAAFLQSLGSVGGAAVERRARWAVRVIISLLTFPGRDEADERAMIEDF 181
>gi|296141453|ref|YP_003648696.1| TetR family transcriptional regulator [Tsukamurella paurometabola
DSM 20162]
gi|296029587|gb|ADG80357.1| transcriptional regulator, TetR family [Tsukamurella paurometabola
DSM 20162]
Length=194
Score = 72.8 bits (177), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 55/172 (32%), Positives = 87/172 (51%), Gaps = 7/172 (4%)
Query 16 AAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIA 75
AA+RI A+A +L R G+ A+ + +LA+ CSRAT+YR + + + R A +A
Sbjct 11 AADRILASAAELFARDGVAAVGMAELAQAAGCSRATLYRYFPNRQALHAAFIQREARAVA 70
Query 76 DGVRSDVETLRGR-ERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTESPLLADF 134
VR + ER++ A+ ++++ +R P F AG +A + F
Sbjct 71 VAVRDRTSGIADPGERLLRALQIAVEEVRGAPPLAAWFAVDEPPAGGIASRSAGIEAVAF 130
Query 135 ATELTGIAGGD-----PQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPA 181
LT I G D P A+W+VRVV+SL+ P + AE L+ ++V PA
Sbjct 131 GL-LTEITGADAPESAPAAARWLVRVVVSLLSHPEPDASAEEELLRRFVIPA 181
>gi|289749798|ref|ZP_06509176.1| transcriptional regulator [Mycobacterium tuberculosis T92]
gi|289690385|gb|EFD57814.1| transcriptional regulator [Mycobacterium tuberculosis T92]
Length=202
Score = 72.8 bits (177), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 96/184 (53%), Gaps = 8/184 (4%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G DW+ R +AA+RI AA L T+ ++ ++++A+ CSRAT+YR + +
Sbjct 3 GTDWL-SARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREAL 61
Query 63 RDVVLTRAAARIADGVRSDV-ETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AG 120
R + R R++ + + + + ER++ +I +L+ +R +P F + G
Sbjct 62 RTAYVHRETRRLSREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGG 121
Query 121 ELAWLTESPLLADFATELTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
E+A +E + A A L + DP + A+WVVR++ SL+ +P ++ ER ++ +
Sbjct 122 EMAGRSEV-IAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE 180
Query 177 YVAP 180
+V P
Sbjct 181 FVVP 184
>gi|253799700|ref|YP_003032701.1| transcriptional regulator [Mycobacterium tuberculosis KZN 1435]
gi|289554956|ref|ZP_06444166.1| transcriptional regulator [Mycobacterium tuberculosis KZN 605]
gi|297633804|ref|ZP_06951584.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN 4207]
gi|297730790|ref|ZP_06959908.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN R506]
gi|313658122|ref|ZP_07815002.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN V2475]
gi|253321203|gb|ACT25806.1| transcriptional regulator [Mycobacterium tuberculosis KZN 1435]
gi|289439588|gb|EFD22081.1| transcriptional regulator [Mycobacterium tuberculosis KZN 605]
gi|328459446|gb|AEB04869.1| transcriptional regulator [Mycobacterium tuberculosis KZN 4207]
Length=202
Score = 72.0 bits (175), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 95/184 (52%), Gaps = 8/184 (4%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G DW+ R +AA+RI AA L T+ ++ ++++A+ CSRAT+YR + +
Sbjct 3 GTDWL-SARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREAL 61
Query 63 RDVVLTRAAARIADGVRSDV-ETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGGA-G 120
R + R R+ + + + + ER++ +I +L+ +R +P F + G
Sbjct 62 RTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPVGG 121
Query 121 ELAWLTESPLLADFATELTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
E+A +E + A A L + DP + A+WVVR++ SL+ +P ++ ER ++ +
Sbjct 122 EMAGRSEV-IAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE 180
Query 177 YVAP 180
+V P
Sbjct 181 FVVP 184
>gi|15608395|ref|NP_215771.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15840701|ref|NP_335738.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|148661042|ref|YP_001282565.1| putative transcriptional regulatory protein [Mycobacterium tuberculosis
H37Ra]
62 more sequence titles
Length=202
Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 95/184 (52%), Gaps = 8/184 (4%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G DW+ R +AA+RI AA L T+ ++ ++++A+ CSRAT+YR + +
Sbjct 3 GTDWL-SARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREAL 61
Query 63 RDVVLTRAAARIADGVRSDV-ETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AG 120
R + R R+ + + + + ER++ +I +L+ +R +P F + G
Sbjct 62 RTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGG 121
Query 121 ELAWLTESPLLADFATELTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
E+A +E + A A L + DP + A+WVVR++ SL+ +P ++ ER ++ +
Sbjct 122 EMAGRSEV-IAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE 180
Query 177 YVAP 180
+V P
Sbjct 181 FVVP 184
>gi|226365192|ref|YP_002782975.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
gi|226243682|dbj|BAH54030.1| putative TetR family transcriptional regulator [Rhodococcus opacus
B4]
Length=197
Score = 71.6 bits (174), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 59/185 (32%), Positives = 96/185 (52%), Gaps = 9/185 (4%)
Query 5 DWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRD 64
DW+ R +AAERI A L G+ A+ + +AR CSRAT+YR + ++
Sbjct 4 DWM-RDERPRVAAERILDVAARLYVENGIAAVGMADVARAAGCSRATLYRYFDSRQALQL 62
Query 65 VVLTRAAARIADGVRSDVETLRGRERVVA-AILLSLQRIRSDPLGKLMFGSIHGG-AGEL 122
+ R A RI V +V G + V+ A+L +++ +R+DP F G A ++
Sbjct 63 AFVHREARRIGALVAEEVSGTGGPKGVIVDAMLTAIRLVRADPTLAAWFQLGDSGLAAQI 122
Query 123 AWLTESPLLADFATELTGIAG--GDPQG--AKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
A +E ++ G AG G+ A+W+VR+++SL+ P +D ER ++E++V
Sbjct 123 AHSSE--VIESLGAAFLGRAGFTGEESSRRARWLVRIIVSLLTVPGVDDADERAMLEQFV 180
Query 179 APAFA 183
APA A
Sbjct 181 APALA 185
>gi|326329199|ref|ZP_08195526.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
gi|325952994|gb|EGD45007.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
Length=196
Score = 71.2 bits (173), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 54/172 (32%), Positives = 81/172 (48%), Gaps = 7/172 (4%)
Query 10 GNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVLTR 69
R +AAERI AA L G++ +D++AR CSRAT+YR + + R
Sbjct 25 AERSELAAERILDAAGALFVERGVDRPGMDEVARAAGCSRATLYRYFENRQALIHAFAHR 84
Query 70 AAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGEL--AWLT 126
A I V V + + RVV A+L L +R P + + G L L
Sbjct 85 EARLITTQVGQAVADISDPQRRVVEAVLACLAAVRERP----HLAAWYSGDSTLLREVLR 140
Query 127 ESPLLADFATELTGIAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYV 178
+SP++ A DP A WV+R++LS + P E+ ERRL+E+++
Sbjct 141 DSPIIRGVAQSYLASGDEDPDLADWVLRIILSFLTEPGEDAATERRLLERFL 192
>gi|289446846|ref|ZP_06436590.1| transcriptional regulator [Mycobacterium tuberculosis CPHL_A]
gi|289419804|gb|EFD17005.1| transcriptional regulator [Mycobacterium tuberculosis CPHL_A]
Length=202
Score = 70.5 bits (171), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 50/184 (28%), Positives = 94/184 (52%), Gaps = 8/184 (4%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
G DW+ R +AA+RI AA L T+ ++ ++++ + CSRAT+YR + +
Sbjct 3 GTDWL-SARRTELAADRILDAAERLFTQRDPASIGMNEIPKAAGCSRATLYRYFDSREAL 61
Query 63 RDVVLTRAAARIADGVRSDV-ETLRGRERVVAAILLSLQRIRSDPLGKLMFGSIHGG-AG 120
R + R R+ + + + + ER++ +I +L+ +R +P F + G
Sbjct 62 RTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGG 121
Query 121 ELAWLTESPLLADFATELTGIAGGDP----QGAKWVVRVVLSLMYWPAENDEAERRLVEK 176
E+A +E + A A L + DP + A+WVVR++ SL+ +P ++ ER ++ +
Sbjct 122 EMAGRSEV-IAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE 180
Query 177 YVAP 180
+V P
Sbjct 181 FVVP 184
>gi|120405418|ref|YP_955247.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119958236|gb|ABM15241.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=193
Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/185 (28%), Positives = 87/185 (48%), Gaps = 10/185 (5%)
Query 3 GNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQI 62
DW+ R +AA+RI AA +L + + ++A CSRAT+YR + +
Sbjct 2 AGDWL-AARRTEVAADRILDAAGELFAAQPAATVGMHEIASAAGCSRATLYRYFENREAL 60
Query 63 RDVVLTRAAARIADGVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSIHGGAGE 121
+ R A R+ + + ++ RER++ +L SL+ +R P F + G
Sbjct 61 YTAYVHREAYRLYVEMTDQITSIADPRERLIEGMLASLRNVRESPALASWFATTQRPIG- 119
Query 122 LAWLTESPLLADFATELTGIAGGDPQG------AKWVVRVVLSLMYWPAENDEAERRLVE 175
A + E + TE I+ G A+W+VRV+ SLM +P ++ ER ++E
Sbjct 120 -AEMAEESEVIKALTEAFVISLGPDDAELVAHRARWLVRVMTSLMLFPGHDETDERAMLE 178
Query 176 KYVAP 180
++V P
Sbjct 179 EFVVP 183
Lambda K H
0.320 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 177363380150
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40