BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1777 Length=434 Score E Sequences producing significant alignments: (Bits) Value gi|15608915|ref|NP_216293.1| cytochrome p450 144 CYP144 [Mycobac... 880 0.0 gi|340626789|ref|YP_004745241.1| putative cytochrome p450 144 CY... 880 0.0 gi|289443245|ref|ZP_06432989.1| cytochrome P450 144 cyp144 [Myco... 879 0.0 gi|31792966|ref|NP_855459.1| cytochrome p450 144 CYP144 [Mycobac... 878 0.0 gi|254550784|ref|ZP_05141231.1| cytochrome P450 144 cyp144 [Myco... 823 0.0 gi|240172007|ref|ZP_04750666.1| putative cytochrome p450 144 CYP... 687 0.0 gi|183982662|ref|YP_001850953.1| cytochrome P450 144A4 Cyp144A4 ... 674 0.0 gi|118618502|ref|YP_906834.1| cytochrome P450 144A4 Cyp144A4 [My... 666 0.0 gi|118472111|ref|YP_885084.1| cytochrome P450 [Mycobacterium sme... 556 3e-156 gi|342860272|ref|ZP_08716924.1| cytochrome P450 [Mycobacterium c... 547 2e-153 gi|118465807|ref|YP_879312.1| cytochrome P450 [Mycobacterium avi... 546 3e-153 gi|41406107|ref|NP_958943.1| hypothetical protein MAP0009 [Mycob... 544 1e-152 gi|254773062|ref|ZP_05214578.1| cytochrome P450 [Mycobacterium a... 541 8e-152 gi|333989588|ref|YP_004522202.1| cytochrome P450 [Mycobacterium ... 540 1e-151 gi|296169829|ref|ZP_06851443.1| P450 heme-thiolate protein [Myco... 538 6e-151 gi|108800388|ref|YP_640585.1| cytochrome P450 [Mycobacterium sp.... 533 2e-149 gi|126436011|ref|YP_001071702.1| cytochrome P450 [Mycobacterium ... 531 9e-149 gi|145224060|ref|YP_001134738.1| cytochrome P450 [Mycobacterium ... 525 7e-147 gi|254821353|ref|ZP_05226354.1| hypothetical protein MintA_15553... 507 2e-141 gi|289750345|ref|ZP_06509723.1| cytochrome P450 144 cyp144 [Myco... 492 6e-137 gi|120404740|ref|YP_954569.1| cytochrome P450 [Mycobacterium van... 487 2e-135 gi|240168791|ref|ZP_04747450.1| cytochrome P450 144A4 Cyp144A4 [... 479 5e-133 gi|226308420|ref|YP_002768380.1| cytochrome P450 [Rhodococcus er... 382 6e-104 gi|169629027|ref|YP_001702676.1| cytochrome P450 [Mycobacterium ... 380 2e-103 gi|229489017|ref|ZP_04382883.1| cytochrome P450 [Rhodococcus ery... 380 2e-103 gi|325674835|ref|ZP_08154522.1| P450 heme-thiolate protein [Rhod... 362 8e-98 gi|312138258|ref|YP_004005594.1| cytochrome p450 monooxygenase [... 362 1e-97 gi|262202609|ref|YP_003273817.1| cytochrome P450 CYP109C2 [Gordo... 361 1e-97 gi|336462084|gb|EGO40926.1| cytochrome P450 [Mycobacterium avium... 353 3e-95 gi|226361810|ref|YP_002779588.1| cytochrome P450 [Rhodococcus op... 350 2e-94 gi|298525274|ref|ZP_07012683.1| conserved hypothetical protein [... 339 4e-91 gi|343926651|ref|ZP_08766149.1| putative cytochrome P450 [Gordon... 294 2e-77 gi|254479888|ref|ZP_05093136.1| Cytochrome P450 superfamily prot... 277 3e-72 gi|254819928|ref|ZP_05224929.1| cytochrome P450 [Mycobacterium i... 239 5e-61 gi|304310422|ref|YP_003810020.1| cytochrome P450 [gamma proteoba... 211 2e-52 gi|126436253|ref|YP_001071944.1| cytochrome P450 [Mycobacterium ... 207 2e-51 gi|108800629|ref|YP_640826.1| cytochrome P450 [Mycobacterium sp.... 207 2e-51 gi|340008437|gb|AEK26941.1| cytochrome P450 [Rhodococcus sp. R04] 207 3e-51 gi|288918525|ref|ZP_06412875.1| cytochrome P450 [Frankia sp. EUN... 201 2e-49 gi|254773741|ref|ZP_05215257.1| cytochrome p450 [Mycobacterium a... 199 6e-49 gi|118466208|ref|YP_880118.1| cytochrome p450 [Mycobacterium avi... 198 2e-48 gi|158312454|ref|YP_001504962.1| cytochrome P450 [Frankia sp. EA... 197 2e-48 gi|108797599|ref|YP_637796.1| cytochrome P450 [Mycobacterium sp.... 196 4e-48 gi|41406766|ref|NP_959602.1| hypothetical protein MAP0668 [Mycob... 196 5e-48 gi|296169455|ref|ZP_06851075.1| unspecific monooxygenase [Mycoba... 196 5e-48 gi|342860318|ref|ZP_08716969.1| hypothetical protein MCOL_15626 ... 194 2e-47 gi|158316454|ref|YP_001508962.1| cytochrome P450 [Frankia sp. EA... 193 4e-47 gi|41406825|ref|NP_959661.1| hypothetical protein MAP0727 [Mycob... 193 5e-47 gi|254818629|ref|ZP_05223630.1| cytochrome p450 [Mycobacterium i... 192 1e-46 gi|342860392|ref|ZP_08717043.1| cytochrome p450 [Mycobacterium c... 191 2e-46 >gi|15608915|ref|NP_216293.1| cytochrome p450 144 CYP144 [Mycobacterium tuberculosis H37Rv] gi|15841246|ref|NP_336283.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|148661585|ref|YP_001283108.1| putative cytochrome p450 144 CYP144 [Mycobacterium tuberculosis H37Ra] 28 more sequence titles Length=434 Score = 880 bits (2275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/434 (99%), Positives = 434/434 (100%), Gaps = 0/434 (0%) Query 1 VRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 +RRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG Sbjct 1 MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 Query 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL Sbjct 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 Query 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM Sbjct 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 Query 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA Sbjct 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 Query 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV Sbjct 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 Query 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE Sbjct 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 Query 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS Sbjct 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 Query 421 ILVRRIERLELAVQ 434 ILVRRIERLELAVQ Sbjct 421 ILVRRIERLELAVQ 434 >gi|340626789|ref|YP_004745241.1| putative cytochrome p450 144 CYP144 [Mycobacterium canettii CIPT 140010059] gi|340004979|emb|CCC44127.1| putative cytochrome p450 144 CYP144 [Mycobacterium canettii CIPT 140010059] Length=434 Score = 880 bits (2273), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/434 (99%), Positives = 433/434 (99%), Gaps = 0/434 (0%) Query 1 VRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 +RRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG Sbjct 1 MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 Query 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGT KPFEMDPLGGPTHVL Sbjct 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTVKPFEMDPLGGPTHVL 120 Query 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM Sbjct 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 Query 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA Sbjct 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 Query 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV Sbjct 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 Query 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE Sbjct 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 Query 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS Sbjct 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 Query 421 ILVRRIERLELAVQ 434 ILVRRIERLELAVQ Sbjct 421 ILVRRIERLELAVQ 434 >gi|289443245|ref|ZP_06432989.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T46] gi|289569842|ref|ZP_06450069.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T17] gi|289416164|gb|EFD13404.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T46] gi|289543596|gb|EFD47244.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T17] Length=434 Score = 879 bits (2271), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/434 (99%), Positives = 433/434 (99%), Gaps = 0/434 (0%) Query 1 VRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 +RRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG Sbjct 1 MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 Query 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL Sbjct 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 Query 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM Sbjct 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 Query 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA Sbjct 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 Query 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPD QQQV Sbjct 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDTQQQV 300 Query 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE Sbjct 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 Query 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS Sbjct 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 Query 421 ILVRRIERLELAVQ 434 ILVRRIERLELAVQ Sbjct 421 ILVRRIERLELAVQ 434 >gi|31792966|ref|NP_855459.1| cytochrome p450 144 CYP144 [Mycobacterium bovis AF2122/97] gi|121637679|ref|YP_977902.1| putative cytochrome p450 144 CYP144 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990163|ref|YP_002644850.1| putative cytochrome p450 144 [Mycobacterium bovis BCG str. Tokyo 172] gi|31618557|emb|CAD94509.1| Probable cytochrome p450 144 CYP144 [Mycobacterium bovis AF2122/97] gi|121493326|emb|CAL71797.1| Probable cytochrome p450 144 CYP144 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773276|dbj|BAH26082.1| putative cytochrome p450 144 [Mycobacterium bovis BCG str. Tokyo 172] gi|260667409|gb|ACX47917.1| cytochrome P450 144 [Mycobacterium bovis] gi|341601706|emb|CCC64379.1| probable cytochrome p450 144 CYP144 [Mycobacterium bovis BCG str. Moreau RDJ] Length=434 Score = 878 bits (2268), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/434 (99%), Positives = 433/434 (99%), Gaps = 0/434 (0%) Query 1 VRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 +RRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG Sbjct 1 MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 Query 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL Sbjct 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 Query 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM Sbjct 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 Query 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA Sbjct 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAA 240 Query 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV Sbjct 241 DPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQV 300 Query 301 RANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 RANPELLGAFIEETLRYEPPFRG YRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE Sbjct 301 RANPELLGAFIEETLRYEPPFRGQYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFE 360 Query 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS Sbjct 361 APGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 420 Query 421 ILVRRIERLELAVQ 434 ILVRRIERLELAVQ Sbjct 421 ILVRRIERLELAVQ 434 >gi|254550784|ref|ZP_05141231.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|294996688|ref|ZP_06802379.1| cytochrome P450 [Mycobacterium tuberculosis 210] gi|297634335|ref|ZP_06952115.1| cytochrome P450 [Mycobacterium tuberculosis KZN 4207] 29 more sequence titles Length=404 Score = 823 bits (2127), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/404 (100%), Positives = 404/404 (100%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS Sbjct 1 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF Sbjct 61 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG Sbjct 121 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT Sbjct 181 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN Sbjct 241 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL Sbjct 301 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ Sbjct 361 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 404 >gi|240172007|ref|ZP_04750666.1| putative cytochrome p450 144 CYP144 [Mycobacterium kansasii ATCC 12478] Length=410 Score = 687 bits (1773), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/407 (82%), Positives = 366/407 (90%), Gaps = 0/407 (0%) Query 28 AELMTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPE 87 A L T + DA+TFFGAE +QDPYPLYERM A G+VHRIA+S FYAVCGWDAV++AI RPE Sbjct 4 AGLRTCSIDASTFFGAECLQDPYPLYERMHATGTVHRIADSSFYAVCGWDAVHDAISRPE 63 Query 88 DFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVM 147 DFSSNLTATMTYTA+GT KPFEMD LGGPTHVLATADDPAHA+HRK ++RHLAAKRIR + Sbjct 64 DFSSNLTATMTYTADGTVKPFEMDALGGPTHVLATADDPAHALHRKFLVRHLAAKRIRAI 123 Query 148 EQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQL 207 EQF Q A RLWVDG++DG IEWMGAMANRLPMMVVA LIG+PD D AQLVKWGYAATQL Sbjct 124 EQFAAQTASRLWVDGLRDGHIEWMGAMANRLPMMVVASLIGVPDADAAQLVKWGYAATQL 183 Query 208 LEGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVM 267 LEGLV ++QL AAGVA+MELSGYI +QF RAAA P+DNLLGELA AC SGE+DTLTAQVM Sbjct 184 LEGLVSHEQLAAAGVAVMELSGYISDQFSRAAAGPQDNLLGELAAACTSGEIDTLTAQVM 243 Query 268 MVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRH 327 MVTLFAAGGESTA+LLGSA WILATRPDIQ+QVR +P+LLGAF+EETLRYE PFRGHYRH Sbjct 244 MVTLFAAGGESTASLLGSATWILATRPDIQRQVRDDPDLLGAFLEETLRYEAPFRGHYRH 303 Query 328 VRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVG 387 VR+ T+L G +LPADSHLLLLWGAANRDPAQFE PGEFRLDR GK HISFGKGAHFCVG Sbjct 304 VRHDTSLAGVDLPADSHLLLLWGAANRDPAQFEIPGEFRLDRGRGKSHISFGKGAHFCVG 363 Query 388 AALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 AALARLEA+IV+R LL+RTSVIEAADVG WLPSILVRR+ERLEL V+ Sbjct 364 AALARLEAQIVVRQLLERTSVIEAADVGQWLPSILVRRLERLELTVR 410 >gi|183982662|ref|YP_001850953.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium marinum M] gi|183175988|gb|ACC41098.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium marinum M] Length=404 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/404 (81%), Positives = 362/404 (90%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M +A DA TFFG E++Q+PYPLYERMRA G VHRIA+SDFYAVCGWDAVN+AI RPEDFS Sbjct 1 MKVASDAMTFFGPETLQNPYPLYERMRAEGPVHRIADSDFYAVCGWDAVNDAISRPEDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATMTY+ G FEMD LGGPTHVLATADDPAHAVHRKL++RHLAA+RIR +E+F Sbjct 61 SNLTATMTYSPAGKIAAFEMDQLGGPTHVLATADDPAHAVHRKLLVRHLAARRIRSLERF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 + A+RLW DG+Q G IEWM A+ANRLPMMVVAELIGLPD DIAQLV+WGY ATQLLEG Sbjct 121 VSETAERLWFDGLQGGRIEWMDAIANRLPMMVVAELIGLPDADIAQLVQWGYGATQLLEG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 LV+ DQL AG+A+M+LSGYI EQF RAAADP++NLLGELATACA+GELD+LTA +MMV Sbjct 181 LVDQDQLADAGIAVMQLSGYITEQFARAAADPQENLLGELATACATGELDSLTANLMMVM 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LFAAGGESTA+LLGSAVWILATRPDIQQQVR NP+LLGAF+EETLRYE PFRGHYRHVRN Sbjct 241 LFAAGGESTASLLGSAVWILATRPDIQQQVRDNPQLLGAFVEETLRYEAPFRGHYRHVRN 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G LPADSHLLL+WGAANRDP QF+AP EFRLDR GGKGHISFGKGAHFCVGAAL Sbjct 301 DTTLGGLTLPADSHLLLMWGAANRDPVQFDAPEEFRLDRPGGKGHISFGKGAHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA+IVLRLLL+RT+VIEAADVG WLPS+LVRR+E LELAV+ Sbjct 361 ARLEAQIVLRLLLERTTVIEAADVGRWLPSMLVRRLENLELAVR 404 >gi|118618502|ref|YP_906834.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium ulcerans Agy99] gi|118570612|gb|ABL05363.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium ulcerans Agy99] Length=404 Score = 666 bits (1719), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/404 (80%), Positives = 360/404 (90%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M +A DA TFFG ES+Q+PYPLYERMRA G VHRIA+S+FYAVCGWDAVN+AI RP DFS Sbjct 1 MKVASDAMTFFGTESLQNPYPLYERMRAEGPVHRIADSEFYAVCGWDAVNDAISRPGDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATMTY+ +G FEMD LGGPTHVLATADDPAHAVHRKL++RHLAA+RIR +E+F Sbjct 61 SNLTATMTYSPDGKVAAFEMDQLGGPTHVLATADDPAHAVHRKLLVRHLAARRIRSLERF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 + A+RLW DG+Q G IEWM A+ANRLPMMVVAELIGLPD DIAQLV+WGY ATQLLEG Sbjct 121 VSETAERLWFDGLQGGRIEWMDAIANRLPMMVVAELIGLPDADIAQLVQWGYGATQLLEG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 LV+ DQL AG+A+M+LSG I EQF RAAADP++NLLGELATACA+GELD+LTA +MMV Sbjct 181 LVDQDQLADAGIAVMQLSGCITEQFARAAADPQENLLGELATACAAGELDSLTANLMMVM 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LFAAGGESTA+LLGSAVWILATRPDIQQQVR NP+LLGAF+EETLRYE PFR HYRHVRN Sbjct 241 LFAAGGESTASLLGSAVWILATRPDIQQQVRDNPQLLGAFVEETLRYEAPFRAHYRHVRN 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G LPADSHLLL+WGAANRDP QF+AP EFRLDR GGKGHISFGKGAHFCVGAAL Sbjct 301 DTTLGGLTLPADSHLLLMWGAANRDPVQFDAPEEFRLDRPGGKGHISFGKGAHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA+IVLRLLL+RT+VIEAADVG WLPS+LVRR+E LELAV+ Sbjct 361 ARLEAQIVLRLLLERTTVIEAADVGRWLPSMLVRRLENLELAVR 404 >gi|118472111|ref|YP_885084.1| cytochrome P450 [Mycobacterium smegmatis str. MC2 155] gi|118173398|gb|ABK74294.1| putative cytochrome P450 144 [Mycobacterium smegmatis str. MC2 155] Length=405 Score = 556 bits (1432), Expect = 3e-156, Method: Compositional matrix adjust. Identities = 265/392 (68%), Positives = 313/392 (80%), Gaps = 0/392 (0%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F E +QDPYPLY RM VH IA+S FYAVCGWDAVN+AI RPE+FSSNLTATMTY Sbjct 11 LFRPECIQDPYPLYRRMLDTAPVHPIADSGFYAVCGWDAVNDAIARPENFSSNLTATMTY 70 Query 100 TAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 A+GT FEM+ LGG +HVLATAD+PAH HRK +L LAA+RIR E F ++ A+ LW Sbjct 71 QADGTVGAFEMESLGGKSHVLATADEPAHTAHRKALLPQLAARRIRAFEPFILETANSLW 130 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 + DG IEWM A+ANRLPMM+V LIG+PD D+ +LV+WGY+ATQ++EGLV DQL Sbjct 131 HSHLHDGHIEWMSAVANRLPMMIVGRLIGVPDADVDKLVRWGYSATQVVEGLVGQDQLTQ 190 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 A VA+MEL+GYI +QF AA DP+DNLLG+LATACA+GE+D LTAQ MM+ LF+AGGEST Sbjct 191 ATVAVMELAGYITDQFRHAAQDPQDNLLGDLATACATGEMDELTAQSMMIILFSAGGEST 250 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 A+L+GSA WILA+RPDIQ+ +RA PELLGAF+EE LRYEPPFRGHYRHV + TTL G +L Sbjct 251 ASLIGSAAWILASRPDIQEHLRAKPELLGAFVEEVLRYEPPFRGHYRHVVHDTTLGGVDL 310 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 PA S LLLLWGAANRDP+ F+AP EFRLDR+ K H+SFGKG HFCVGAALARLEA +VL Sbjct 311 PAGSRLLLLWGAANRDPSHFDAPDEFRLDRSSAKSHLSFGKGTHFCVGAALARLEALVVL 370 Query 400 RLLLDRTSVIEAADVGGWLPSILVRRIERLEL 431 R LL T+ I A D G WLPS+LVRR+ LEL Sbjct 371 RHLLHNTANITAGDTGPWLPSLLVRRLAHLEL 402 >gi|342860272|ref|ZP_08716924.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342132650|gb|EGT85879.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=404 Score = 547 bits (1409), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 261/404 (65%), Positives = 318/404 (79%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT+ A FF +E++QDPYPLY+RMRA VHRI +S FYAVCGWDAV EA+ R EDFS Sbjct 1 MTVLDSAVRFFSSEAIQDPYPLYDRMRAEAPVHRIGDSVFYAVCGWDAVQEAVDRVEDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM Y +GT P +M G P H+LATADDP HA+HRK++L HL+A+R+R++E+F Sbjct 61 SNLTATMVYHDDGTITPLDMGQPGAPMHILATADDPVHAMHRKILLPHLSARRVRIIEEF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 VQ ADRLW + + DG IEWM A+ANRLPMMVV +L+GLPD D+ L++ GYA T LL+G Sbjct 121 AVQTADRLWEENLHDGQIEWMSAIANRLPMMVVCKLLGLPDDDVDTLIRLGYATTTLLDG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V +Q+ AG+A M+LSGY+ E F++A P L+G+LA ASGEL+ L A +M+T Sbjct 181 IVTPEQVEQAGLAAMQLSGYVMEHFEKARGKPDSGLIGDLAARYASGELEQLPALGIMLT 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+A GESTA+LLGSA WIL RP IQ+Q+R NPELL AFIEETLR+E PFRGHYRHV Sbjct 241 LFSAAGESTASLLGSAGWILTDRPAIQRQLRENPELLSAFIEETLRFEAPFRGHYRHVWR 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G E+PA +HLLL+WGAANRDP+ FEAP EFRLDRA K H+SFGKG HFCVGAAL Sbjct 301 DTTLGGVEVPAGAHLLLMWGAANRDPSHFEAPNEFRLDRASAKSHVSFGKGVHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA IVLR+LL+RTS I+A D+G WLPSILVRR ERL+LAV+ Sbjct 361 ARLEAHIVLRMLLERTSWIDATDIGEWLPSILVRRRERLQLAVR 404 >gi|118465807|ref|YP_879312.1| cytochrome P450 [Mycobacterium avium 104] gi|118167094|gb|ABK67991.1| cytochrome P450 [Mycobacterium avium 104] Length=404 Score = 546 bits (1406), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 263/404 (66%), Positives = 314/404 (78%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M + A FFG+E++QDPYPLYERM A VHRI +S FYAVCGWDAV+EAI R EDFS Sbjct 1 MAVLDSATRFFGSEAIQDPYPLYERMHAEAPVHRIGDSVFYAVCGWDAVHEAIERVEDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM + +GT PF+M G P H LATADDP HAVHRK++L HL+AKRIR++E+F Sbjct 61 SNLTATMVFHEDGTVTPFDMGAPGAPMHALATADDPVHAVHRKILLPHLSAKRIRIIEEF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 Q ADRLW + + DG IEWM A+ANRLPMMVV L+GLPD D+ +L++ GYA T LL+G Sbjct 121 ATQTADRLWDENLSDGRIEWMSAIANRLPMMVVCRLLGLPDDDVDKLIRLGYATTTLLDG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V +QL AG+A +ELSGY+ E F++A+ P +L+ +LA CA+GEL+ L A +M+T Sbjct 181 IVAPEQLEQAGMAAIELSGYVLEHFEKASEKPESSLMADLAARCAAGELEQLPALGIMLT 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+A GESTA+LLGSA WILA RP IQ+Q+R NPELL FIEETLR+E PFRGHYRHV Sbjct 241 LFSAAGESTASLLGSAAWILADRPAIQRQLRENPELLSTFIEETLRFEAPFRGHYRHVWR 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G ELP +HLLL+WGAANRDP F+ P EFRLDRA K H+SFGKG HFCVGAAL Sbjct 301 DTTLGGIELPEGAHLLLMWGAANRDPTHFKDPNEFRLDRAAAKSHLSFGKGVHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA IVLR LL+RTS I+A DVG WLPSILVRR ERL LAV+ Sbjct 361 ARLEAHIVLRRLLERTSWIDATDVGDWLPSILVRRRERLGLAVR 404 >gi|41406107|ref|NP_958943.1| hypothetical protein MAP0009 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394455|gb|AAS02326.1| hypothetical protein MAP_0009 [Mycobacterium avium subsp. paratuberculosis K-10] Length=441 Score = 544 bits (1402), Expect = 1e-152, Method: Compositional matrix adjust. Identities = 262/404 (65%), Positives = 314/404 (78%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M + A FFG+E++QDPYPLYERM A +HRI +S FYAVCGWDAV+EAI R EDFS Sbjct 38 MAVLDSATRFFGSEAIQDPYPLYERMHAEAPMHRIGDSVFYAVCGWDAVHEAIERVEDFS 97 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM + +GT PF+M G P H LATADDP HAVHRK++L HL+AKRIR++E+F Sbjct 98 SNLTATMVFHEDGTVTPFDMGAPGAPMHALATADDPVHAVHRKILLPHLSAKRIRIIEEF 157 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 Q ADRLW + + DG IEWM A+ANRLPMMVV L+GLPD D+ +L++ GYA T LL+G Sbjct 158 ATQTADRLWDENLSDGRIEWMSAIANRLPMMVVCRLLGLPDDDVDKLIRLGYATTTLLDG 217 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V +QL AG+A +ELSGY+ E F++A+ P +L+ +LA CA+GEL+ L A +M+T Sbjct 218 IVAPEQLEQAGMAAIELSGYVLEHFEKASEKPESSLMADLAARCAAGELEQLPALGIMLT 277 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+A GESTA+LLGSA WILA RP IQ+Q+R NPELL FIEETLR+E PFRGHYRHV Sbjct 278 LFSAAGESTASLLGSAAWILADRPAIQRQLRENPELLSTFIEETLRFEAPFRGHYRHVWR 337 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G ELP +HLLL+WGAANRDP F+ P EFRLDRA K H+SFGKG HFCVGAAL Sbjct 338 DTTLGGIELPEGAHLLLMWGAANRDPTHFKDPNEFRLDRAAAKSHLSFGKGVHFCVGAAL 397 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA IVLR LL+RTS I+A DVG WLPSILVRR ERL LAV+ Sbjct 398 ARLEAHIVLRRLLERTSWIDATDVGDWLPSILVRRRERLGLAVR 441 >gi|254773062|ref|ZP_05214578.1| cytochrome P450 [Mycobacterium avium subsp. avium ATCC 25291] Length=404 Score = 541 bits (1394), Expect = 8e-152, Method: Compositional matrix adjust. Identities = 261/404 (65%), Positives = 312/404 (78%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M + A FFG+E++QDPYPLYERM A VHRI +S FY VCGWDAV+EAI R EDFS Sbjct 1 MAVLDSATRFFGSEAIQDPYPLYERMHAEAPVHRIGDSVFYGVCGWDAVHEAIERVEDFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM + +GT PF+M G P H LATADDP HAVHRK++L HL+AKRIR++E+F Sbjct 61 SNLTATMVFHEDGTVTPFDMGAPGAPMHALATADDPVHAVHRKILLPHLSAKRIRIIEEF 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 Q ADRLW + + DG IEWM A+ANRLPMMVV L+GLPD D+ +L++ GYA T LL+G Sbjct 121 ATQTADRLWDENLSDGRIEWMSAIANRLPMMVVCRLLGLPDDDVDKLIRLGYATTTLLDG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V +QL AG+A +ELSGY+ E F++A+ P +L+ +LA CA+GEL+ L A +M+T Sbjct 181 IVAPEQLEQAGMAAIELSGYVLEHFEKASEKPESSLMADLAARCAAGELEQLPALGIMLT 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 F+A GESTA+LLGSA WILA RP IQ+Q+R NPELL FIEETLR+E PFRGHYRHV Sbjct 241 PFSAAGESTASLLGSAAWILADRPAIQRQLRENPELLSTFIEETLRFEAPFRGHYRHVWR 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G ELP +HLLL+WGAANRDP F+ P EFRLDRA K H+SFGKG HFCVGAAL Sbjct 301 DTTLGGIELPEGAHLLLMWGAANRDPTHFKDPNEFRLDRAAAKSHLSFGKGVHFCVGAAL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEA IVLR LL+RTS I+A DVG WLPSILVRR ERL LAV+ Sbjct 361 ARLEAHIVLRRLLERTSWIDATDVGDWLPSILVRRRERLGLAVR 404 >gi|333989588|ref|YP_004522202.1| cytochrome P450 [Mycobacterium sp. JDM601] gi|333485556|gb|AEF34948.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium sp. JDM601] Length=406 Score = 540 bits (1392), Expect = 1e-151, Method: Compositional matrix adjust. Identities = 262/404 (65%), Positives = 315/404 (78%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 M+ DA FFG ++QDP PLY+ MR G V+RI +S FYAVCGWDAV EA+ R EDFS Sbjct 3 MSAVVDATDFFGHAAIQDPNPLYDTMRRRGGVNRIGDSAFYAVCGWDAVTEAVDRVEDFS 62 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM Y +GT PF+M LGGP H LATADDP HA HRKL+L HL+AKR+RV+E+F Sbjct 63 SNLTATMVYHDDGTVTPFDMGALGGPMHALATADDPLHAAHRKLLLPHLSAKRVRVIEEF 122 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 A RLW + G +EWM MANRLPM VVA L+GLP+ D+ L++ GYA T LL+G Sbjct 123 AEATAKRLWAEAGDGGQVEWMSTMANRLPMTVVARLLGLPEDDVDTLIRLGYATTTLLDG 182 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V QL AAGVA MELSGY+ E F++AA +P+ L+G+LAT +GEL+ L A +M+T Sbjct 183 IVSASQLEAAGVAAMELSGYVLEHFEKAAENPQPGLIGDLATRTKTGELEQLPALAIMLT 242 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+A GESTA+LLGSA WILA RP +Q+Q+RA PELL AF+EETLR E PFRGHYRHV Sbjct 243 LFSAAGESTASLLGSAAWILADRPHVQEQLRARPELLDAFLEETLRCESPFRGHYRHVVA 302 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G ELPADS LLL+WGAANRDP FEAP +FRLDR+ G+GH++FGKGAHFCVGAAL Sbjct 303 DTTLAGVELPADSRLLLMWGAANRDPRHFEAPNDFRLDRSAGRGHLAFGKGAHFCVGAAL 362 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLEARIV R+LL++TS IEAADVG WLPSILVRR+ERL+L ++ Sbjct 363 ARLEARIVFRMLLEQTSWIEAADVGQWLPSILVRRLERLQLDIR 406 >gi|296169829|ref|ZP_06851443.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895506|gb|EFG75206.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=406 Score = 538 bits (1386), Expect = 6e-151, Method: Compositional matrix adjust. Identities = 265/393 (68%), Positives = 301/393 (77%), Gaps = 0/393 (0%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F + +Q+P LY RM G VHRI +S FYAV W AVNEA+ R DFSSNLTATM Y Sbjct 12 LFDEQFIQNPQLLYARMHRTGPVHRIGDSRFYAVSSWTAVNEAVARCADFSSNLTATMMY 71 Query 100 TAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 G F + LGGPT LATAD+P H+ HRK +L LAAKRIR E F A RLW Sbjct 72 QPGGAVTAFPVGELGGPTQALATADEPVHSAHRKTLLPQLAAKRIRAFEPFIADTAARLW 131 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 QDG IEWM AMANRLPMM+V +IG+PD DI ++++WGYAATQ++EGLV DQ+ A Sbjct 132 DAHAQDGRIEWMSAMANRLPMMIVGRIIGVPDADIDKIIRWGYAATQVVEGLVTQDQMDA 191 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 AG+A+MELSGYI EQF AA+DP DNLLG+LA ACASGELD L A MM+TLF+AGGEST Sbjct 192 AGIAVMELSGYITEQFQNAASDPHDNLLGDLAAACASGELDDLAALAMMITLFSAGGEST 251 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 A+L+GSA W+LATRPD+Q+QVR PELLGAF+EE LRYEPPFRGHYRHV + T L G EL Sbjct 252 ASLIGSAAWVLATRPDVQRQVRERPELLGAFLEEVLRYEPPFRGHYRHVVDDTELCGAEL 311 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 PA S LLLLWGAANRDP F+ P EFRLDR GKGHISFGKG HFCVGAALARLEA IVL Sbjct 312 PAGSRLLLLWGAANRDPTHFDHPDEFRLDRPAGKGHISFGKGIHFCVGAALARLEANIVL 371 Query 400 RLLLDRTSVIEAADVGGWLPSILVRRIERLELA 432 R LL RTS I AADVG WLPS+L RR+ERL+LA Sbjct 372 RQLLARTSDITAADVGNWLPSLLFRRLERLQLA 404 >gi|108800388|ref|YP_640585.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119869517|ref|YP_939469.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108770807|gb|ABG09529.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119695606|gb|ABL92679.1| cytochrome P450 [Mycobacterium sp. KMS] Length=406 Score = 533 bits (1374), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 261/395 (67%), Positives = 312/395 (79%), Gaps = 0/395 (0%) Query 39 TFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMT 98 + F +QDP PLY RM AG+VHRI +S FYAV GWDAV EAI R +DFSSNLTATM Sbjct 11 SLFDDRYIQDPGPLYARMHRAGAVHRIGDSGFYAVSGWDAVTEAIARCDDFSSNLTATML 70 Query 99 YTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRL 158 Y G F + LGGPT LATAD+PAH+VHRK +L HLA KRIR E F A +L Sbjct 71 YQPGGAVTEFHLGELGGPTQALATADEPAHSVHRKALLPHLAVKRIREFEPFIDDTAAQL 130 Query 159 WVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLV 218 W ++DG IEWMGA+ANRLPMM+V +IG+PD D+ +L++WGY+ATQ++EGLV QL Sbjct 131 WDTHLRDGRIEWMGAVANRLPMMIVGRIIGVPDADVDKLIRWGYSATQVVEGLVTQQQLD 190 Query 219 AAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGES 278 AA VA++ELSGYI +QF RAAA PR+NLLG+LA ACA G LD + A MM+TLF+AGGES Sbjct 191 AASVAVLELSGYIADQFRRAAAGPRENLLGDLAAACADGTLDDMAALAMMITLFSAGGES 250 Query 279 TAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTE 338 TA+L+GSA WILATR DIQQ+VRA PELL AF+EE LR EPPFRGHYRHV + TTL + Sbjct 251 TASLIGSAAWILATRQDIQQRVRARPELLDAFLEEVLRCEPPFRGHYRHVVHDTTLCDVD 310 Query 339 LPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIV 398 LPA S LLLLWGAANRDP+ F+ PG+FRLDR G+GH++FG+GAHFCVGAALARLEARIV Sbjct 311 LPAGSRLLLLWGAANRDPSHFDEPGDFRLDRPAGRGHMAFGRGAHFCVGAALARLEARIV 370 Query 399 LRLLLDRTSVIEAADVGGWLPSILVRRIERLELAV 433 +R LL+RTS ++A +VG WLPS+LVRR+ERLELAV Sbjct 371 IRQLLERTSQVDAVEVGRWLPSLLVRRLERLELAV 405 >gi|126436011|ref|YP_001071702.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126235811|gb|ABN99211.1| cytochrome P450 [Mycobacterium sp. JLS] Length=406 Score = 531 bits (1368), Expect = 9e-149, Method: Compositional matrix adjust. Identities = 260/395 (66%), Positives = 311/395 (79%), Gaps = 0/395 (0%) Query 39 TFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMT 98 + F +QDP PLY RM AG+VHRI +S FYAV GWDAV EAI R +DFSSNLTATM Sbjct 11 SLFDDRYIQDPGPLYARMHRAGAVHRIGDSGFYAVSGWDAVTEAIARCDDFSSNLTATML 70 Query 99 YTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRL 158 Y G F + LGGPT LATAD+PAH+VHRK +L HLA KRIR E F A +L Sbjct 71 YQPGGAVTEFHLGELGGPTQALATADEPAHSVHRKALLPHLAVKRIRAFEPFIDDTAAQL 130 Query 159 WVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLV 218 W ++DG IEWMGA+ANRLPMM+V +IG+PD D+ +L++WGY+ATQ++EGLV QL Sbjct 131 WDTHLRDGRIEWMGAVANRLPMMIVGRIIGVPDADVDKLIRWGYSATQVVEGLVTQQQLD 190 Query 219 AAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGES 278 AA VA++ELSGYI +QF RAAA R+NLLG+LA ACA G LD + A MM+TLF+AGGES Sbjct 191 AASVAVLELSGYIADQFRRAAAGSRENLLGDLAAACADGTLDDMAALAMMITLFSAGGES 250 Query 279 TAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTE 338 TA+L+GSA WILATR DIQQ+VRA PELL AF+EE LR EPPFRGHYRHV + TTL + Sbjct 251 TASLIGSAAWILATRQDIQQRVRARPELLDAFLEEVLRCEPPFRGHYRHVVHDTTLCDVD 310 Query 339 LPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIV 398 LPA S LLLLWGAANRDP+ F+ PG+FRLDR G+GH++FG+GAHFCVGAALARLEARIV Sbjct 311 LPAGSRLLLLWGAANRDPSHFDDPGDFRLDRPAGRGHMAFGRGAHFCVGAALARLEARIV 370 Query 399 LRLLLDRTSVIEAADVGGWLPSILVRRIERLELAV 433 +R LL+RTS ++A +VG WLPS+LVRR+ERLELAV Sbjct 371 IRQLLERTSQVDAVEVGRWLPSLLVRRLERLELAV 405 >gi|145224060|ref|YP_001134738.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315444396|ref|YP_004077275.1| cytochrome P450 [Mycobacterium sp. Spyr1] gi|145216546|gb|ABP45950.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315262699|gb|ADT99440.1| cytochrome P450 [Mycobacterium sp. Spyr1] Length=403 Score = 525 bits (1351), Expect = 7e-147, Method: Compositional matrix adjust. Identities = 252/395 (64%), Positives = 307/395 (78%), Gaps = 0/395 (0%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 FFG ++QDP P+Y+ MR +V+RI S FYAVCGWDAV EA+ R +DFSSNLTATM + Sbjct 9 FFGGAAIQDPAPMYDMMRDRAAVNRIGESAFYAVCGWDAVQEAVNRVDDFSSNLTATMVF 68 Query 100 TAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 +GT PFEM LGGP H LATADDP HA HRKL+L HL+AKRIRV+EQF A RLW Sbjct 69 HDDGTVTPFEMGALGGPMHALATADDPLHASHRKLLLPHLSAKRIRVIEQFAEVTAHRLW 128 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 D + DG IEWM A+ANR+PMMVVA L+GLP+ D+ +L++ GYA T LL+G+V QL A Sbjct 129 SDALVDGHIEWMSAIANRVPMMVVARLLGLPEDDVDELIRLGYATTTLLDGIVSATQLEA 188 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 AG A MEL+ Y+ + F++A DP+ L+ +LA SGEL+ L+A +M+TLF+A GEST Sbjct 189 AGTAAMELATYVLQHFEKATGDPQPGLMSDLAWRTQSGELEQLSALAIMLTLFSAAGEST 248 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 A+LLGSA WIL RP +Q+Q+RA+P LLGAFIEETLR+E PFRGHYRHV T L G EL Sbjct 249 ASLLGSAAWILTDRPAVQEQLRADPGLLGAFIEETLRFESPFRGHYRHVVRDTALAGVEL 308 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 PADS LLL+WGAANRDP QF + +FRLDR+ KGH++FGKGAHFCVGAALARLEARIVL Sbjct 309 PADSRLLLMWGAANRDPRQFNSANDFRLDRSSAKGHVAFGKGAHFCVGAALARLEARIVL 368 Query 400 RLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 +LL+RT+ IEAADVG WLPSILVRR+E L L ++ Sbjct 369 AMLLERTTWIEAADVGPWLPSILVRRLEHLRLKIR 403 >gi|254821353|ref|ZP_05226354.1| hypothetical protein MintA_15553 [Mycobacterium intracellulare ATCC 13950] Length=416 Score = 507 bits (1305), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 248/391 (64%), Positives = 300/391 (77%), Gaps = 0/391 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 + + A FFG+E++QDPYPLY+RMRA VHRI S+FYAVCGWDAV EA+ R EDFS Sbjct 13 VAVLDSAIRFFGSEAIQDPYPLYDRMRAEAPVHRIGGSEFYAVCGWDAVQEAVERVEDFS 72 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATM + +GT P +M P G H LATADDP HA+HRK++L HL+AKR+R++E+F Sbjct 73 SNLTATMVFHEDGTVAPLDMGPPGDSMHALATADDPVHAMHRKILLPHLSAKRVRIIEEF 132 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 Q ADRLW ++DG IEWM +ANRLPMMVV +L+GLPD D+ +L++ GYA T LL+G Sbjct 133 AAQTADRLWEQNLRDGEIEWMSGIANRLPMMVVCKLLGLPDDDVDKLIRLGYATTTLLDG 192 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 +V QL AG A MEL GY+ E+F+R +A+ L+ +LA SGEL+ A +M+T Sbjct 193 IVTPAQLAEAGAAAMELFGYVLERFERTSANGEYGLIADLAARYVSGELEQTPALGIMLT 252 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+A GESTA+LLGSA WIL RP IQQQ+R PELL AFIEETLR+E PFRGHYRHV Sbjct 253 LFSAAGESTASLLGSAAWILTDRPAIQQQLREKPELLSAFIEETLRFEAPFRGHYRHVWR 312 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 TTL G +PADSHLLL+WGAANRDPA FEAP EFRLDRA K H+SFGKG HFCVGAAL Sbjct 313 DTTLGGVAVPADSHLLLMWGAANRDPAHFEAPNEFRLDRAATKSHMSFGKGVHFCVGAAL 372 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSI 421 ARLEA IVLR+LL+RT+ I+AA+VG WLPSI Sbjct 373 ARLEAHIVLRMLLERTTWIDAAEVGEWLPSI 403 >gi|289750345|ref|ZP_06509723.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T92] gi|289690932|gb|EFD58361.1| cytochrome P450 144 cyp144 [Mycobacterium tuberculosis T92] Length=247 Score = 492 bits (1266), Expect = 6e-137, Method: Compositional matrix adjust. Identities = 238/239 (99%), Positives = 239/239 (100%), Gaps = 0/239 (0%) Query 1 VRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 +RRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG Sbjct 1 MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAG 60 Query 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL Sbjct 61 SVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVL 120 Query 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM Sbjct 121 ATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPM 180 Query 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAA 239 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAA Sbjct 181 MVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAA 239 >gi|120404740|ref|YP_954569.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119957558|gb|ABM14563.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=406 Score = 487 bits (1253), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 236/394 (60%), Positives = 294/394 (75%), Gaps = 0/394 (0%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F E +QDP+PLY RM A VHR+ +SDFYAVCGWDA+ EA+ RP DFSSNLT M Y Sbjct 12 LFHDEFLQDPHPLYARMHAEAPVHRVGDSDFYAVCGWDAITEAVARPGDFSSNLTGAMRY 71 Query 100 TAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 A+GT +D LG PT LATADDPAHA HRKL++ +LAAKR+R +E F LW Sbjct 72 QADGTVSLLPLDTLGSPTQALATADDPAHAAHRKLLVPYLAAKRVRALETFAENTMHALW 131 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 +EWM +A+RLPM VV +LIG+P D+ ++ W YA+TQ+LEG V+ L A Sbjct 132 QQMPAGAPVEWMAVVADRLPMTVVCKLIGVPAEDVDRIAAWAYASTQILEGRVDEHTLTA 191 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 AG A +EL+GYI ++ RA+ DP DNLLG +ATACA+GEL+ LTAQVM+VTLF+AGGEST Sbjct 192 AGTAALELAGYISDKLGRASLDPGDNLLGCIATACAAGELNNLTAQVMLVTLFSAGGEST 251 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 AAL+GSA I+ATRPD+Q+++RA+P L+ AF+EE LR+EPPFRGHYRHV L G EL Sbjct 252 AALIGSATQIIATRPDVQRRLRADPGLIPAFLEEVLRFEPPFRGHYRHVVRDCALAGKEL 311 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 A S LLLLWGAANRDPA+F+AP EF+++R K HI+FGKGAHFC+GAALAR EARIV+ Sbjct 312 TAGSRLLLLWGAANRDPARFDAPNEFQIERPNSKAHIAFGKGAHFCIGAALARFEARIVI 371 Query 400 RLLLDRTSVIEAADVGGWLPSILVRRIERLELAV 433 LLL TS ++AA G WLPS+LVRR++ L L + Sbjct 372 DLLLRHTSWVDAAGPGWWLPSLLVRRLDELPLTM 405 >gi|240168791|ref|ZP_04747450.1| cytochrome P450 144A4 Cyp144A4 [Mycobacterium kansasii ATCC 12478] Length=404 Score = 479 bits (1232), Expect = 5e-133, Method: Compositional matrix adjust. Identities = 235/404 (59%), Positives = 290/404 (72%), Gaps = 0/404 (0%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT D FF ++QDPYPLY R+R+ G VHR+ +S+FY W A+ + + RPE FS Sbjct 1 MTATIDPAEFFDDAAIQDPYPLYARLRSEGGVHRVGDSEFYLASSWAAITDVVNRPEVFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQF 150 SNLTATMT+T G PF MD +GG TH+L TADDP HA HRKL++ AKR++ ++ Sbjct 61 SNLTATMTFTPAGGVVPFPMDGVGGRTHILVTADDPVHAAHRKLMIGQFTAKRVQALQPL 120 Query 151 TVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEG 210 + + LW DG IEWM A+ANRLPM VVA+LIG+P+ D QL +WGYA+TQLL+G Sbjct 121 ITRVFETLWGTAAYDGTIEWMDAVANRLPMSVVADLIGVPEADADQLARWGYASTQLLDG 180 Query 211 LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVT 270 L+ D+L A+ A+ ELS YI + AA PRD+L+G LA A A+GELD TAQ+++V+ Sbjct 181 LMSADELAASMAAIGELSAYITTRLRVAATSPRDDLMGVLAKAYAAGELDAFTAQLILVS 240 Query 271 LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN 330 LF+AGGESTA+LLG+AV ILAT +Q+++R P+LLG FIEETLR EPPFR HYRHV Sbjct 241 LFSAGGESTASLLGTAVSILATDAALQRRLRDQPDLLGVFIEETLRLEPPFRAHYRHVLG 300 Query 331 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAAL 390 T L G LP +S +LLLWGAANRDPA F+AP EFRLDR KGH+SFGKG HFC+GA L Sbjct 301 DTELAGAALPRNSRVLLLWGAANRDPAHFDAPDEFRLDRPISKGHMSFGKGIHFCLGAPL 360 Query 391 ARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 ARLE VLR+LLDRT EAADVG WLPS+L RR E L L V Sbjct 361 ARLETATVLRMLLDRTEWFEAADVGPWLPSVLARRREFLRLTVS 404 >gi|226308420|ref|YP_002768380.1| cytochrome P450 [Rhodococcus erythropolis PR4] gi|226187537|dbj|BAH35641.1| cytochrome P450 [Rhodococcus erythropolis PR4] Length=407 Score = 382 bits (981), Expect = 6e-104, Method: Compositional matrix adjust. Identities = 192/400 (48%), Positives = 263/400 (66%), Gaps = 3/400 (0%) Query 36 DANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTA 95 D N F + ++ DPYPLY+ +R V+RI ++DFY V W+ V EA+ R EDFSSNLT Sbjct 7 DINPFLPS-NIDDPYPLYDVLRREHPVYRIPDTDFYLVSTWELVTEAVSRTEDFSSNLTG 65 Query 96 TMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAA 155 + T +G+A F+M+ G HVLATAD+P H RKLVL L AKRIR +E ++ Sbjct 66 VLVRTPDGSAVTFDMNGGGQAVHVLATADEPDHQHQRKLVLPTLVAKRIRALEPTMLEYT 125 Query 156 DRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVEND 215 +LW +G I+W+ ++A+ LP+ +VA LIGLP D+ QL+ W Y +T+LL G+V + Sbjct 126 QQLWDNGFDGPHIDWVTSIADTLPLQMVAALIGLPTADVPQLLAWSYDSTELLSGIVTAE 185 Query 216 QLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAG 275 + + EL+GY++ +F A +P D+LLG+L C +GEL A +M+V L AG Sbjct 186 RFTDVVTSAAELTGYLYSKFREARTNPIDDLLGDLVRCCDAGELSEDVAVLMLVQLVGAG 245 Query 276 GESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLD 335 GESTA L+ ++ +LA RP+IQ Q+R +P L+ AF+EETLR E PFRGH+RHV T L Sbjct 246 GESTAGLIANSARLLAERPEIQTQLREDPLLVSAFLEETLRLESPFRGHHRHVNADTNLG 305 Query 336 GTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEA 395 G LPA SHL+LLWG+ANRDP F P LDRA + H +FGKGAHFCVGAALARLEA Sbjct 306 GVALPAGSHLILLWGSANRDPESFAEPHAMNLDRANLRAHFAFGKGAHFCVGAALARLEA 365 Query 396 RIVLRLLLDRTS--VIEAADVGGWLPSILVRRIERLELAV 433 + + +LL+ +S +++ W+PS+ VRR + L LAV Sbjct 366 KTAIAVLLENSSHVTVDSEFPPRWVPSMFVRRHQSLRLAV 405 >gi|169629027|ref|YP_001702676.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169240994|emb|CAM62022.1| Probable cytochrome P450 [Mycobacterium abscessus] Length=402 Score = 380 bits (977), Expect = 2e-103, Method: Compositional matrix adjust. Identities = 203/400 (51%), Positives = 250/400 (63%), Gaps = 2/400 (0%) Query 36 DANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTA 95 + + F + ++DPYP Y R+R V + +S FY V WD V EA R EDFSSNLTA Sbjct 2 NTDELFDPQVLEDPYPFYRRLRETAPVWPVGDSGFYFVSRWDLVVEATERAEDFSSNLTA 61 Query 96 TMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAA 155 + +AEG A M P PTHVLAT DDP H HR+LVL L A+RI +E Q Sbjct 62 ALMKSAEGLAVA-PMGPPADPTHVLATGDDPLHHAHRRLVLPTLVARRITALEPVMAQTG 120 Query 156 DRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVEND 215 LW G+ I+WM AM + LPM +VA LIGLP D+ QLV+WGY++T++L GL Sbjct 121 SCLWERGVNGDGIDWMAAMGDALPMTMVARLIGLPAGDVPQLVQWGYSSTEMLGGLNTPQ 180 Query 216 QLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAG 275 + M L Y+ E + A P D+LLG LA AC G++ +++V L AG Sbjct 181 RQAQVVTDTMHLVLYLREHLEEELAAPGDDLLGYLAQACNRGDISLDIGVMILVQLVGAG 240 Query 276 GESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLD 335 GESTA L+G+AV IL P +QQ++R N LL F+EE LR E PFRGH+RHV TTL Sbjct 241 GESTAGLMGNAVRILGENPRLQQRIRENRALLPTFLEEALRLESPFRGHHRHVLTDTTLG 300 Query 336 GTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEA 395 G +LPA SHL LLWGAANRDPA FE P RLDR +GHI+FGKG HFCVGAALARLEA Sbjct 301 GVQLPAGSHLTLLWGAANRDPAIFEDPDVLRLDRPSPRGHITFGKGLHFCVGAALARLEA 360 Query 396 RIVLRLLLDRTSVIE-AADVGGWLPSILVRRIERLELAVQ 434 R + LLLDRT D W+PSI+VRR ++LEL V Sbjct 361 RTAINLLLDRTREFAIKPDGAHWVPSIMVRRHQKLELEVS 400 >gi|229489017|ref|ZP_04382883.1| cytochrome P450 [Rhodococcus erythropolis SK121] gi|229324521|gb|EEN90276.1| cytochrome P450 [Rhodococcus erythropolis SK121] Length=413 Score = 380 bits (977), Expect = 2e-103, Method: Compositional matrix adjust. Identities = 192/401 (48%), Positives = 263/401 (66%), Gaps = 3/401 (0%) Query 36 DANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTA 95 D N F + ++ DPYPLY+ +R V+RI ++DFY V W+ V EA+ R +DFS+NLT Sbjct 7 DINPFLPS-NIDDPYPLYDVLRREHPVYRIPDTDFYLVSTWELVTEAVSRTDDFSNNLTG 65 Query 96 TMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAA 155 + T +G+A F+M+ G HVLATAD+P H RKLVL L AKRIR +E + Sbjct 66 VLVRTPDGSAVTFDMNGGGQAVHVLATADEPDHQHQRKLVLPTLVAKRIRALEPAMTEYT 125 Query 156 DRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVEND 215 +LW +G IEW+ ++A+ LP+ +VA LIGLP D+ QL+ W Y +T+LL G+V + Sbjct 126 QQLWDNGFDGRRIEWVTSVADTLPLQMVATLIGLPAHDVPQLLAWSYDSTELLSGIVTAE 185 Query 216 QLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAG 275 +L + EL+GY++ +F A A P D+LLG+L C +GEL A +M+V L AG Sbjct 186 RLTGVVTSAAELTGYLYSKFREARAHPVDDLLGDLVRCCDAGELSEDVAVLMLVQLVGAG 245 Query 276 GESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLD 335 GESTA L+ ++ +LA RP++Q Q+R +P L+GAF+EETLR E PFRGH+RHV TTL Sbjct 246 GESTAGLIANSARLLAERPEMQTQLREDPLLVGAFLEETLRLESPFRGHHRHVNADTTLG 305 Query 336 GTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEA 395 G LPA SHL+LLWG+ANRDP F P LDR + H +FGKGAHFCVGAALARLEA Sbjct 306 GLALPAGSHLILLWGSANRDPESFVEPQVMNLDRVNPRAHFAFGKGAHFCVGAALARLEA 365 Query 396 RIVLRLLLDRTS--VIEAADVGGWLPSILVRRIERLELAVQ 434 + + +LL+ ++ ++ W+PS+ VRR +RL L V Sbjct 366 KTAIAVLLENSAHVTVDPEFPPRWVPSMFVRRHQRLHLNVS 406 >gi|325674835|ref|ZP_08154522.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707] gi|325554421|gb|EGD24096.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707] Length=403 Score = 362 bits (929), Expect = 8e-98, Method: Compositional matrix adjust. Identities = 197/401 (50%), Positives = 252/401 (63%), Gaps = 3/401 (0%) Query 36 DANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTA 95 D F + DPYPLY +R VHR+ +DF+ V W+ V EA+ RPEDFSSNLT Sbjct 2 DGLGVFDPAHLDDPYPLYATLRERDPVHRVPGTDFHLVSSWELVTEALARPEDFSSNLTG 61 Query 96 TMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAA 155 M A+G F+MD G HVLATADDP+HA HRKLVL L KRIR + Sbjct 62 VMVQRADGPPVTFDMDGGGRAVHVLATADDPSHATHRKLVLAQLT-KRIRTLGPTVRALV 120 Query 156 DRLWVDGMQ-DGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVEN 214 D LW G++ D EW MA+ LP+ +VA LIGLP D+ QL+ W Y +T++L G+V Sbjct 121 DELWDAGLRADDTFEWAREMADALPLALVASLIGLPQSDVPQLLSWSYDSTEMLGGIVTE 180 Query 215 DQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAA 274 +L + L+GY+ +F A DP+ +LLG LA AC G+L A +++V L A Sbjct 181 GRLPTLVASAAALTGYLHTEFTAAKRDPQTDLLGALAHACNEGDLTDDVAVLVLVQLVGA 240 Query 275 GGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTL 334 GGESTA L+ +A ILAT ++Q ++R +P+L+ F++E LR E PFRGH+RHV TTL Sbjct 241 GGESTAGLIANATRILATNQELQDRLRRDPQLIDPFLDEALRLESPFRGHHRHVVTDTTL 300 Query 335 DGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLE 394 G L A SHLLLLWGAANRDPA+F P RLDR KGH++FGKG HFCVG+ALAR+E Sbjct 301 GGVRLSAGSHLLLLWGAANRDPARFVDPDTARLDRPNLKGHLAFGKGIHFCVGSALARME 360 Query 395 ARIVLRLLLDRTSVIEAADVGG-WLPSILVRRIERLELAVQ 434 A L LL+RT+ AD G W+PS+LVRR L L + Sbjct 361 ALAALTTLLERTTSFTIADGGAEWVPSLLVRRHRSLPLELN 401 >gi|312138258|ref|YP_004005594.1| cytochrome p450 monooxygenase [Rhodococcus equi 103S] gi|311887597|emb|CBH46909.1| putative cytochrome P450 monooxygenase [Rhodococcus equi 103S] Length=408 Score = 362 bits (928), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 196/396 (50%), Positives = 251/396 (64%), Gaps = 3/396 (0%) Query 41 FGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYT 100 F + DPYPLY +R VHR+ +DF V W+ V EA+ RPEDFSSNLT M Sbjct 12 FDPAHLDDPYPLYATLRERDPVHRVPGTDFRLVSSWELVTEALARPEDFSSNLTGVMVQR 71 Query 101 AEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWV 160 A+G F+MD G HVLATADDP+HA HRKLVL L KRIR + D+LW Sbjct 72 ADGPPVTFDMDGGGRAVHVLATADDPSHAAHRKLVLAQLT-KRIRTLGPTVRALVDQLWD 130 Query 161 DGMQ-DGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 G++ D EW MA+ LP+ +VA LIGLP D+ QL+ W Y +T++L G+V D+L Sbjct 131 AGLRADDTFEWAREMADALPLALVASLIGLPQSDVPQLLSWSYDSTEMLGGIVTEDRLPT 190 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 + L+GY+ +F A DP+ +LLG LA AC G+L A +++V L AGGEST Sbjct 191 LVASAAALTGYLHTEFTAAKRDPQTDLLGALAHACNEGDLTDDVAVLVLVQLVGAGGEST 250 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 A L+ +A ILAT ++Q ++R +P+L+ F++E LR E PFRGH+RHV TTL G L Sbjct 251 AGLIANATRILATNQELQDRLRRDPQLIDPFLDEALRLESPFRGHHRHVVTDTTLGGVRL 310 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 A SHLLLLWGAANRDPA+F P LDR KGH++FGKG HFCVG+ALAR+EA L Sbjct 311 SAGSHLLLLWGAANRDPARFVDPDTASLDRPNLKGHLAFGKGIHFCVGSALARMEALAAL 370 Query 400 RLLLDRTSVIEAADVGG-WLPSILVRRIERLELAVQ 434 LL+RT+ AD G W+PS+LVRR L L + Sbjct 371 TTLLERTTSFTIADGGAEWVPSLLVRRHRSLPLELN 406 >gi|262202609|ref|YP_003273817.1| cytochrome P450 CYP109C2 [Gordonia bronchialis DSM 43247] gi|262085956|gb|ACY21924.1| cytochrome P450 CYP109C2 [Gordonia bronchialis DSM 43247] Length=394 Score = 361 bits (926), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 188/387 (49%), Positives = 253/387 (66%), Gaps = 1/387 (0%) Query 46 VQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTA 105 + DPY +R V R +S+FYAV WD + EA+ R +DFSSNLTATM + +G Sbjct 4 LDDPYAGLADLRDNNPVARFGDSEFYAVTSWDLIAEAVARTDDFSSNLTATMVWHDDGQV 63 Query 106 KPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQD 165 F + LG HVLATADDP H +HR++++ L A+R+ +E F Q LW G+ Sbjct 64 TGFPVAELGSSMHVLATADDPRHRMHRRIIMPSLTARRVSRLEPFIEQTLVDLWATGVVG 123 Query 166 GCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALM 225 ++W+ ++A RLPM VVAEL+GLP+ DIA+L++W +A+T LL+G+V DQL +A A+ Sbjct 124 DRVDWVESIAQRLPMAVVAELLGLPEYDIAELIRWSFASTVLLDGVVTADQLESATAAVG 183 Query 226 ELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGS 285 ELS Y+ FDRA A+P D++L +LA G+LD +A ++++ L AAG EST +LLG+ Sbjct 184 ELSAYLTAAFDRALAEPGDDVLRDLARLVHCGDLDQDSAVMILIQLVAAGAESTVSLLGT 243 Query 286 AVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHL 345 +VW+LA PDI + A+ EL+ F+EE LR E PFRGHYRHV N TTL T LPA SHL Sbjct 244 SVWLLARHPDIVAALAADRELIPVFVEEVLRLESPFRGHYRHVVNDTTLGQTPLPAGSHL 303 Query 346 LLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDR 405 L+WGAANRDPA F+ LD + + H++FGKG H CVGA LARLEAR+ + LLD Sbjct 304 YLMWGAANRDPAIFDYADSISLDPSDRRSHMAFGKGIHLCVGAPLARLEARLGIAQLLDA 363 Query 406 TSVIEAADVG-GWLPSILVRRIERLEL 431 TS A W S++VRR+ L L Sbjct 364 TSEFRLASPDPQWERSLMVRRLTTLPL 390 >gi|336462084|gb|EGO40926.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=264 Score = 353 bits (906), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 174/264 (66%), Positives = 208/264 (79%), Gaps = 0/264 (0%) Query 171 MGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGY 230 M A+ANRLPMMVV L+GLPD D+ +L++ GYA T LL+G+V +QL AG+A +ELSGY Sbjct 1 MSAIANRLPMMVVCRLLGLPDDDVDKLIRLGYATTTLLDGIVAPEQLEQAGMAAIELSGY 60 Query 231 IFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWIL 290 + E F++A+ P +L+ +LA CA+GEL+ L A +M+TLF+A GESTA+LLGSA WIL Sbjct 61 VLEHFEKASEKPESSLMADLAARCAAGELEQLPALGIMLTLFSAAGESTASLLGSAAWIL 120 Query 291 ATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWG 350 A RP IQ+Q+R NPELL FIEETLR+E PFRGHYRHV TTL G ELP +HLLL+WG Sbjct 121 ADRPAIQRQLRENPELLSTFIEETLRFEAPFRGHYRHVWRDTTLGGIELPEGAHLLLMWG 180 Query 351 AANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIE 410 AANRDP F+ P EFRLDRA K H+SFGKG HFCVGAALARLEA IVLR LL+RTS I+ Sbjct 181 AANRDPTHFKDPNEFRLDRAAAKSHLSFGKGVHFCVGAALARLEAHIVLRRLLERTSWID 240 Query 411 AADVGGWLPSILVRRIERLELAVQ 434 A DVG WLPSILVRR ERL LAV+ Sbjct 241 ATDVGDWLPSILVRRRERLGLAVR 264 >gi|226361810|ref|YP_002779588.1| cytochrome P450 [Rhodococcus opacus B4] gi|226240295|dbj|BAH50643.1| cytochrome P450 [Rhodococcus opacus B4] Length=412 Score = 350 bits (898), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 191/396 (49%), Positives = 252/396 (64%), Gaps = 3/396 (0%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F + +P LY +R VHR+A +DF+ V WD V EA R EDFSS+LT + Sbjct 11 IFDPAHLDEPNELYRILREHSPVHRVAGTDFFLVSTWDLVTEAANRTEDFSSHLTGVLVQ 70 Query 100 TAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 EG F+MD G HVLATADDP H HRKLVL L +RIR + D LW Sbjct 71 QPEGPPTTFDMDGGGRAIHVLATADDPTHLHHRKLVLPTLG-RRIRALTPTVQSLVDTLW 129 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 +G++DG I+W MA+RLP+ +VA LIGLP+ D+ QL+ W Y +T++L G+V+ ++L Sbjct 130 DEGVRDGRIDWAAEMADRLPLTMVAHLIGLPEEDVPQLLAWAYDSTEMLGGIVDANRLGP 189 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 ++ EL+ Y+ + RA + P ++LLG LA AC +GEL A ++++ L AGGEST Sbjct 190 LVASVTELAAYLRAELVRARSGPSEDLLGVLAHACNAGELLEDVAVLVLLQLVGAGGEST 249 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 A L+ +A +L+T PD+Q ++R P L+ AF++E LR E PFRGH+RHV TTL G +L Sbjct 250 AGLIANAARLLSTHPDVQTRLRQEPALVDAFLDEALRLESPFRGHHRHVVADTTLGGVDL 309 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 PA SHLLLLWGAANRDPA F+ PGE LDR + H++FGKG HFCVG+ALAR+EA Sbjct 310 PAGSHLLLLWGAANRDPAAFDRPGEIVLDRPHIRSHLAFGKGVHFCVGSALARMEALTAT 369 Query 400 RLLLDRTSVIEAAD--VGGWLPSILVRRIERLELAV 433 LL RT AD WLPS+LVRR L L + Sbjct 370 TTLLARTEQFSLADDAESRWLPSLLVRRHSALPLRI 405 >gi|298525274|ref|ZP_07012683.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298495068|gb|EFI30362.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=168 Score = 339 bits (870), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 168/168 (100%), Positives = 168/168 (100%), Gaps = 0/168 (0%) Query 267 MMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYR 326 MMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYR Sbjct 1 MMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYR 60 Query 327 HVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCV 386 HVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCV Sbjct 61 HVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCV 120 Query 387 GAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 434 GAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ Sbjct 121 GAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ 168 >gi|343926651|ref|ZP_08766149.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433] gi|343763403|dbj|GAA13075.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433] Length=387 Score = 294 bits (752), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 156/368 (43%), Positives = 218/368 (60%), Gaps = 10/368 (2%) Query 45 SVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGT 104 ++ DP R V +I +S F+AV WD + + + RPEDFSSNLTATM +G+ Sbjct 3 ALDDPA-FLSRFHTGFPVQQIGDSPFFAVGSWDLIADVVRRPEDFSSNLTATMVCHDDGS 61 Query 105 AKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQ 164 F + LG HVLATAD P H +HR LV+ L RIR +E + + D W +G+ Sbjct 62 VSEFPVAGLGDAIHVLATADGPRHRLHRSLVMPSLTPARIRALEPYVAEVVDTAWSEGLD 121 Query 165 DGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVAL 224 + I+W A+A R+P+ VV EL+GLP DI L W A L++G++ QL A A+ Sbjct 122 EDTIDWTTAVAQRVPITVVTELLGLPHEDIDDLAHWAGATNVLIDGVITPGQLTTATTAV 181 Query 225 MELSGYIFEQFDRAAADPRD-----NLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 EL+ Y+ + D A + R+ +L ++A+A A +LD A ++++ L AAG +ST Sbjct 182 AELTAYLGDALDSALRNEREGTPGRGVLADIASAVARADLDRPAAVMILLQLVAAGSDST 241 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 +LL +AV ILA P++ ++R P+L+ AF+EE LR E PFRGH+RHV TTL L Sbjct 242 VSLLTNAVRILARHPEVAARLRHAPDLIPAFVEEALRLESPFRGHFRHVVADTTLGDARL 301 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRA----GGKGHISFGKGAHFCVGAALARLEA 395 PA SH+ L+W NRDP F+A LDRA G H++FGKG H CVGA LARL+ Sbjct 302 PAGSHIYLMWRVGNRDPEHFDAAPAIDLDRATARSGHGSHLAFGKGLHLCVGAGLARLQG 361 Query 396 RIVLRLLL 403 R+ + LL Sbjct 362 RLAIARLL 369 >gi|254479888|ref|ZP_05093136.1| Cytochrome P450 superfamily protein [marine gamma proteobacterium HTCC2148] gi|214039450|gb|EEB80109.1| Cytochrome P450 superfamily protein [marine gamma proteobacterium HTCC2148] Length=411 Score = 277 bits (709), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 144/394 (37%), Positives = 224/394 (57%), Gaps = 6/394 (1%) Query 44 ESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEG 103 E +++PYP Y + A V+++ N++ Y V +++ + +DFS+NLT + + G Sbjct 13 EVIENPYPFYRELLAHAPVYQVPNTEVYLVSSPKLIHQVLKNQQDFSANLTGVLISDSSG 72 Query 104 TAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGM 163 F+ GG +A AD+P H+VHRKLV+ L A+++ ME A + Sbjct 73 QPTLFDFSQFGGTVDAIANADEPFHSVHRKLVMPQLTARKVMAMESQVRSWAGEALSQLL 132 Query 164 QDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVA 223 G + +G +AN +P++V+A L+GLP D+ +L+ W ++ +L G +++V G + Sbjct 133 AQGGGDCIGGLANAIPVLVMARLMGLPIADLDKLLDWSFSGGDILAGTATLERMVELGAS 192 Query 224 LMELSGYIFEQFDRA----AADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGEST 279 E+S Y+ F RA + D D +L +LA G +D A + + L A GEST Sbjct 193 TAEMSQYLRGHFQRALQLDSLDTVDCVLNDLAQGVTEGLIDEEEAVAIAIVLVGAAGEST 252 Query 280 AALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTEL 339 ++L+GSA+ ILA PD+Q ++R +PEL+ ++IEE +R E PF+GHYR V + T L G + Sbjct 253 SSLVGSAIRILARDPDLQSRLRQSPELIESYIEEVVRLETPFKGHYRTVLHQTELGGISV 312 Query 340 PADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVL 399 A + + LLW AANRD F P L+R H+ FG G HFC+GA LAR+E RI+L Sbjct 313 SAGAKVFLLWAAANRDETVFSNPEMIDLNRENKNEHLGFGHGIHFCIGARLARMETRIIL 372 Query 400 RLLLDRTS--VIEAADVGGWLPSILVRRIERLEL 431 LL RT +++ + SI VRR++ LEL Sbjct 373 EELLQRTKKFSLQSEHSEKHVSSIFVRRLQCLEL 406 >gi|254819928|ref|ZP_05224929.1| cytochrome P450 [Mycobacterium intracellulare ATCC 13950] Length=403 Score = 239 bits (611), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 140/391 (36%), Positives = 210/391 (54%), Gaps = 4/391 (1%) Query 37 ANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTAT 96 A+ +Q+PY Y +R V + +D A+ + ++EA+ RPEDFSS + Sbjct 4 ASMLLDPAVLQNPYAFYAMLREQAPVWMVPGTDVVAISTFALLSEAVARPEDFSSIMRCL 63 Query 97 MTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAAD 156 + +G + PT LATAD P H HR+ V L A+R+R +E + Sbjct 64 LYRDQDGLPARLDFGEAAMPT--LATADPPVHTTHRRAVFPELVARRMRTLEDDIRALSA 121 Query 157 RLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQ 216 + DG ++M + N +P+ VVA LIG D D QL++ + +T ++ G + D+ Sbjct 122 AAVKQALDDGSFDFMAKIGNMVPITVVARLIGFRDIDPMQLLEAAFDSTTMVGGTMSMDE 181 Query 217 LVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGG 276 L + +I +Q + +L + A +G L A +++ T+ +AGG Sbjct 182 LSTFVARTETIEAWIADQIAGTGEGGEEGILLAVRRALDAGTLRIGEATIILHTMLSAGG 241 Query 277 ESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDG 336 EST +LLG+AV +LA P +QQ++R P+ + F+EE LR E PFR R V TTL G Sbjct 242 ESTTSLLGNAVGMLAENPGLQQRLREKPQDIDVFVEEALRLESPFRQMMRSVPRDTTLGG 301 Query 337 TELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEAR 396 E+ + S +LLL+ A NRDPAQF+ P L R K H++FG G HFCVGAALAR+EAR Sbjct 302 VEIASGSTVLLLFAAGNRDPAQFKHPDRIDLTRESPKRHLAFGHGIHFCVGAALARIEAR 361 Query 397 IVLRLLLDRTS--VIEAADVGGWLPSILVRR 425 VL +L++T ++ W+ S+LVRR Sbjct 362 AVLGAILEQTRCFTLDEDRAPRWVDSLLVRR 392 >gi|304310422|ref|YP_003810020.1| cytochrome P450 [gamma proteobacterium HdN1] gi|301796155|emb|CBL44361.1| cytochrome P450 [gamma proteobacterium HdN1] Length=468 Score = 211 bits (537), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 128/394 (33%), Positives = 198/394 (51%), Gaps = 10/394 (2%) Query 47 QDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGT-- 104 Q+PY Y +R V+R+ N Y + +D + FSS + G Sbjct 64 QNPYAFYRMLRDEYPVYRLRNG-IYCISRYDDIQTVSRDTNTFSSEHQGVIANLKPGQDL 122 Query 105 ---AKPFE-MDPLGG-PTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLW 159 + FE M LG P VLAT+D P H V RK+ L A ++ +E + + + Sbjct 123 LQQVRRFEKMTALGIIPADVLATSDPPQHTVERKIGHTSLNAHFVKSLEPEVEKLSTNML 182 Query 160 VDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVA 219 + G +E+M A RLPM+++ L+GLP+ D ++ KW G+ + +L Sbjct 183 APLLDAGEMEFMQAFGWRLPMVLIIRLLGLPEQDFTKIKKWCVDTLNSQNGIQTSAELAQ 242 Query 220 AGVALMELSGYIFEQFDRAAADPRDNLLGELATAC--ASGELDTLTAQVMMVTLFAAGGE 277 + V+ + Y + Q+ + +P +NL+G LA + A+ D A + L AG + Sbjct 243 SYVSAINFLDYCWTQYLKVKTNPGNNLMGILAKSADDAATPFDDKKAVSAIFQLLIAGSD 302 Query 278 STAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGT 337 S+A +G+A+ +L R D+Q+++RA+P L+ FIEE R E F+GH+R V T L G Sbjct 303 SSATTMGNALKLLIERLDLQEKMRADPALVNDFIEEVFRLESAFQGHFRWVTKDTALHGV 362 Query 338 ELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARI 397 +LP S + L+W A NRD FE P E L R GK H++FG G H C+G LAR+E RI Sbjct 363 QLPRGSRIFLMWAAGNRDERFFENPDELILGRKNGKKHLTFGHGLHACLGRELARMEIRI 422 Query 398 VLRLLLDRTSVIEAADVGGWLPSILVRRIERLEL 431 VL+ L T + ++ S+ R + L + Sbjct 423 VLQQFLTHTRNLHITGETPFVASMFARTLVTLPI 456 >gi|126436253|ref|YP_001071944.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236053|gb|ABN99453.1| cytochrome P450 [Mycobacterium sp. JLS] Length=426 Score = 207 bits (528), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 143/401 (36%), Positives = 210/401 (53%), Gaps = 26/401 (6%) Query 31 MTIAKDANTFFGAES-VQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDF 89 MT D+ +F S V DP+P Y+ +R V N+ AV GW+A N E+F Sbjct 1 MTADFDSVDYFTDPSLVPDPHPYYDHIREKNPVCCPINNGVLAVTGWEAANTVYKDSENF 60 Query 90 SSNLT-----ATMTYTAEG--TAKPFEMDPLGGPTHV-LATADDPAHAVHRKLVLRHLAA 141 SS + M +T EG E P + + T D P H R ++ R L Sbjct 61 SSCVAVMGPFTPMPFTPEGDDICAQLEAHRTEIPMYEHMVTMDPPQHTDARSILSRLLTP 120 Query 142 KRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWG 201 KR++ E F + ADR + + DG E++ A A ++VVA+L+G+P+ D + + Sbjct 121 KRLKENEDFMWRLADRHIDEFIADGKCEFLAAYAKPFSLLVVADLLGVPEEDHEEF-REA 179 Query 202 YAATQLLEGLVENDQLVAAGVALM----ELSGYIFEQFDRAAADPRDNLLGELATACASG 257 + A + + D V A L + S YI E+ + PRD++L +ATA Sbjct 180 FGAERPGSNIGGLDHEVIAANPLAWADEKFSRYIEERRE----SPRDDVLTSIATAKYP- 234 Query 258 ELDTLTAQVMMVT-----LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIE 312 D T +V+ V LFAAG E+TA LLG+A+ +LA RPDIQQQ+R + L+ FIE Sbjct 235 --DGSTPEVVDVVRTATFLFAAGQETTAKLLGAAMRVLADRPDIQQQLRDDRSLIPVFIE 292 Query 313 ETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGG 372 E LR + P + +R R TTL +PA + +++ GAANRDP +F+ P EF LDR Sbjct 293 ECLRMDSPVKSVFRMARKTTTLGDAAVPAGTTVMVSPGAANRDPKRFDNPHEFSLDRKNV 352 Query 373 KGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAAD 413 + HI+F +G H C GA LAR+E R+ + +LDR + I ++ Sbjct 353 REHIAFSRGIHSCPGAPLARVEGRVSIERILDRMADITVSE 393 >gi|108800629|ref|YP_640826.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119869768|ref|YP_939720.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108771048|gb|ABG09770.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119695857|gb|ABL92930.1| cytochrome P450 [Mycobacterium sp. KMS] Length=426 Score = 207 bits (528), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 143/401 (36%), Positives = 210/401 (53%), Gaps = 26/401 (6%) Query 31 MTIAKDANTFFGAES-VQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDF 89 MT D+ +F S V DP+P Y+ +R V N+ AV GW+A N E+F Sbjct 1 MTADFDSVDYFTDPSLVPDPHPYYDHIREKNPVCCPINNGVLAVTGWEAANTVYKDSENF 60 Query 90 SSNLT-----ATMTYTAEG--TAKPFEMDPLGGPTHV-LATADDPAHAVHRKLVLRHLAA 141 SS + M +T EG E P + + T D P H R ++ R L Sbjct 61 SSCVAVMGPFTPMPFTPEGDDICAQLEAHRTEIPMYEHMVTMDPPQHTDARSILSRLLTP 120 Query 142 KRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWG 201 KR++ E F + ADR + + DG E++ A A ++VVA+L+G+P+ D + + Sbjct 121 KRLKENEDFMWRLADRHIDEFIADGQCEFLAAYAKPFSLLVVADLLGVPEEDHEEF-REA 179 Query 202 YAATQLLEGLVENDQLVAAGVALM----ELSGYIFEQFDRAAADPRDNLLGELATACASG 257 + A + + D V A L + S YI E+ + PRD++L +ATA Sbjct 180 FGAERPGSNIGGLDHEVIAANPLAWADEKFSRYIEERRE----SPRDDVLTSIATAKYP- 234 Query 258 ELDTLTAQVMMVT-----LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIE 312 D T +V+ V LFAAG E+TA LLG+A+ +LA RPDIQQQ+R + L+ FIE Sbjct 235 --DGSTPEVVDVVRTATFLFAAGQETTAKLLGAAMRVLADRPDIQQQLRDDRSLIPVFIE 292 Query 313 ETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGG 372 E LR + P + +R R TTL +PA + +++ GAANRDP +F+ P EF LDR Sbjct 293 ECLRMDSPVKSVFRMARKTTTLGDAAVPAGTTVMVSPGAANRDPKRFDNPHEFSLDRKNV 352 Query 373 KGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAAD 413 + HI+F +G H C GA LAR+E R+ + +LDR + I ++ Sbjct 353 REHIAFSRGIHSCPGAPLARVEGRVSIERILDRMADITVSE 393 >gi|340008437|gb|AEK26941.1| cytochrome P450 [Rhodococcus sp. R04] Length=430 Score = 207 bits (527), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 140/434 (33%), Positives = 225/434 (52%), Gaps = 47/434 (10%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT + N F E V+DPYP Y+ +R V R + + V G++ + + + FS Sbjct 1 MTDIETKNFFTDPELVEDPYPYYDALREGCPVTREPHHNVMMVTGYEEAIQVLSDEQTFS 60 Query 91 SNLTATMTYTA--------EGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAK 142 S ++ T ++ + T E P L T D P H HR L++R + K Sbjct 61 SCISVTGPFSGLPACPESDDITDFIEEHRPSLPMNDQLPTMDPPQHTDHRGLLMRLITPK 120 Query 143 RIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGY 202 R++ E F + ADRL D + G +++ A M+V+A+L+G+P+ D Sbjct 121 RLKENEAFIERIADRLLDDLLARGEGDYITGFAAPFAMLVIADLLGVPESD--------- 171 Query 203 AATQLLEGLVENDQLVAAGVALMELSG---------YIFEQF-----DRAAADPRDNLLG 248 + +EGL V G +L G +++++F DR A +P +++L Sbjct 172 -HQEFIEGLKIQ---VEKGFSLGSTEGETLKLNPLEFLYKKFGQYIEDRRA-NPTEDVLT 226 Query 249 ELATAC-ASGELDTLTAQVMMV-TLFAAGGESTAALLGSAVWILATRPDIQQQVRANPEL 306 LATA G L + + + +F+AG E+T LL SA+ I+A +P++Q+ +R+ P+ Sbjct 227 GLATATFPDGTLPPVDDVLRIAANVFSAGQETTVRLLSSALRIIAEQPELQKTLRSEPDR 286 Query 307 LGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFR 366 + FIEETLR+E P +G +R + TT+ G ++ A + ++L+ GAANRDP QF P EF Sbjct 287 IPNFIEETLRFESPIKGDFRLAKTPTTVGGVDVSAGTIMMLVNGAANRDPRQFSDPNEFD 346 Query 367 LDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAAD---------VGGW 417 +DR + HI+FG+G H C GA LAR E R+ + LL+RTS I ++ G+ Sbjct 347 IDRRNARTHIAFGRGVHSCPGAPLARTEGRVGIARLLERTSEIRISEKVHGPEDDRKFGY 406 Query 418 LPSILVRRIERLEL 431 LP+ ++R + L L Sbjct 407 LPTFILRGLLALHL 420 >gi|288918525|ref|ZP_06412875.1| cytochrome P450 [Frankia sp. EUN1f] gi|288350044|gb|EFC84271.1| cytochrome P450 [Frankia sp. EUN1f] Length=429 Score = 201 bits (510), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 139/390 (36%), Positives = 206/390 (53%), Gaps = 22/390 (5%) Query 40 FFGAES-VQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMT 98 FF ES V++PYP ++ +RA V + + AV G+ E + FSS + Sbjct 9 FFNDESLVENPYPYFDDLRATCPVLPLPHLGVVAVTGYAEATEVYRDVDTFSSCNSVVGP 68 Query 99 YTAEGTAKPFEMDPLGGP----------THVLATADDPAHAVHRKLVLRHLAAKRIRVME 148 + P E D +G + T D P H R LV+R L KR++ E Sbjct 69 FAV--FPVPLEGDDVGAIIDEHRDQLPMNEHMVTMDPPMHTNERALVMRMLTPKRLQENE 126 Query 149 QFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVK-WGYAAT-- 205 +F A R + + G E++ A A M+ VA+++G+P+ D + K +G + + Sbjct 127 EFIQGLAGRQLDEFIDSGRCEFIRAYAQPFAMLAVADVLGVPEADHERFRKGFGLSTSPG 186 Query 206 QLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATAC-ASGELDTLTA 264 Q+ G + +L A G S YI ++ +PR+++L ++ATA G + + A Sbjct 187 QIGAGGDSDGELNALGWLDNWFSKYIEDR----RQNPRNDVLTQMATATYPDGSIPEVIA 242 Query 265 QVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRG 323 V T LFAAG E+TA LLG+ + LA P++Q ++RAN EL+ IEE+LR E P + Sbjct 243 VVRAATFLFAAGQETTARLLGAVLKYLAENPEVQDELRANRELIPDLIEESLRVESPVKA 302 Query 324 HYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAH 383 +R R TT+ G E+ A + ++LL GAANRDP FE P EFR DR + HI+FG+G H Sbjct 303 DFRLARRNTTVGGVEVAAGTPVMLLNGAANRDPRHFECPAEFRHDRKNVRQHIAFGRGVH 362 Query 384 FCVGAALARLEARIVLRLLLDRTSVIEAAD 413 C G LAR+EARI L +LDRT I ++ Sbjct 363 SCPGGPLARVEARISLERILDRTRDIRLSE 392 >gi|254773741|ref|ZP_05215257.1| cytochrome p450 [Mycobacterium avium subsp. avium ATCC 25291] Length=426 Score = 199 bits (507), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 137/397 (35%), Positives = 203/397 (52%), Gaps = 30/397 (7%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT + F A+ QDPY ++ +R G V R + AV G+ V A E FS Sbjct 1 MTDLAQVDYFTDADVAQDPYDYWDYLREQGPVFREPHYGVVAVTGYQEVQAAFKDVESFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATA--------------DDPAHAVHRKLVL 136 + G P P G L A D P H R L+ Sbjct 61 A------VNAIGGPFPPLPFTPEGDDISELIEAHRHEFPIFEHMVVMDPPEHDKARSLLG 114 Query 137 RHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQ 196 R L +R++ + + Q ADR + + + +G E++ A + +A+L+G+PD D Q Sbjct 115 RLLTPRRLQENKDYIWQLADRQFDEFIANGYCEFLSEYAKPFATLAIADLLGVPDEDRPQ 174 Query 197 LVKWGYA--ATQLLEGLVENDQLVAAGVALME--LSGYIFEQFDRAAADPRDNLLGELAT 252 + + A A G ++++ + + + ++ SGYI ++ +R PRD++L LAT Sbjct 175 IRRNLGAGNAPGARVGALDHEPVGSNPLQYLDDLFSGYIADRRER----PRDDVLTGLAT 230 Query 253 AC-ASGELDTLTAQVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAF 310 A G L V T LFAAG E+ LL +AV +L +P++Q Q+RA+ L+G F Sbjct 231 ATYPDGSTPPLLEVVRPATFLFAAGQETVTKLLSAAVQVLGDQPELQAQLRADRGLIGPF 290 Query 311 IEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRA 370 IEE LR + P + +R R TTL G +PA + ++L GAANRDP +FE+P EFR+DR Sbjct 291 IEEALRMQSPTKVDFRLARKTTTLGGVHIPAGTVIMLCLGAANRDPRKFESPNEFRIDRK 350 Query 371 GGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTS 407 + HI+FG+G H C GA LAR+E +I + LLDRTS Sbjct 351 NVREHIAFGRGIHTCAGAPLARVEGQITINRLLDRTS 387 >gi|118466208|ref|YP_880118.1| cytochrome p450 [Mycobacterium avium 104] gi|118167495|gb|ABK68392.1| cytochrome p450 [Mycobacterium avium 104] Length=426 Score = 198 bits (503), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 137/397 (35%), Positives = 202/397 (51%), Gaps = 30/397 (7%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT + F A+ QDPY ++ +R G V R + AV G+ V A E FS Sbjct 1 MTDLAQVDYFTDADVAQDPYDYWDYLREQGPVFREPHYGVVAVTGYQEVQAAFKDVESFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATA--------------DDPAHAVHRKLVL 136 + G P P G L A D P H R L+ Sbjct 61 A------VNAIGGPFPPLPFTPEGDDISELIEAHRHEFPIFEHMVVMDPPEHDKARSLLG 114 Query 137 RHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQ 196 R L +R++ + + Q ADR + + + +G E++ A + +A+L+G+PD D Q Sbjct 115 RLLTPRRLQENKDYIWQLADRQFDEFIANGHCEFLSEYAKPFATLAIADLLGVPDEDRPQ 174 Query 197 LVKWGYA--ATQLLEGLVENDQLVAAGVALME--LSGYIFEQFDRAAADPRDNLLGELAT 252 + + A A G ++++ + + + ++ SGYI ++ +R PRD++L LAT Sbjct 175 IRRNLGAGNAPGARVGALDHEPVGSNPLQYLDDLFSGYIADRRER----PRDDVLTGLAT 230 Query 253 AC-ASGELDTLTAQVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAF 310 A G L V T LFAAG E+ LL +AV +L +P++Q Q+RA+ L+G F Sbjct 231 ATYPDGSTPPLLEVVRPATFLFAAGQETVTKLLSAAVQVLGDQPELQAQLRADRGLIGPF 290 Query 311 IEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRA 370 IEE LR + P + +R R TTL G +PA + ++L GAANRDP +FE P EFR+DR Sbjct 291 IEEALRMQSPTKVDFRLARKTTTLGGVHIPAGTVIMLCLGAANRDPRKFENPNEFRIDRK 350 Query 371 GGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTS 407 + HI+FG+G H C GA LAR+E +I + LLDRTS Sbjct 351 NVREHIAFGRGIHTCAGAPLARVEGQITINRLLDRTS 387 >gi|158312454|ref|YP_001504962.1| cytochrome P450 [Frankia sp. EAN1pec] gi|158107859|gb|ABW10056.1| cytochrome P450 [Frankia sp. EAN1pec] Length=428 Score = 197 bits (502), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 133/387 (35%), Positives = 203/387 (53%), Gaps = 16/387 (4%) Query 40 FFGAESV-QDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMT 98 FF ES+ +DPYP ++ +R+ V + + AV G+D +E + FSS + Sbjct 9 FFNDESLAEDPYPYFDELRSVCPVLPLPHLGVVAVTGYDEAHEVYRDVDTFSSCNSVVGP 68 Query 99 YTAEGTAKPFEMDPLGG---------PTHV-LATADDPAHAVHRKLVLRHLAAKRIRVME 148 + P E D +G P + + T D P H R LV+R L KR++ E Sbjct 69 FAT--FPVPLEGDEVGAIIDRHRDQLPMNEHMVTMDPPMHTRERALVMRMLTPKRLQENE 126 Query 149 QFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLL 208 F + AD+ + + DG E++ A A M+ VA+++G+ + D Q + G+ T Sbjct 127 AFIWRLADQQLDEFIADGRCEFIRAYAQPFSMLAVADVLGVLESD-HQRFREGFGLTVSP 185 Query 209 EGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATAC-ASGELDTLTAQVM 267 + +Q AL L + + +PR+++L ++A A G +T+ V Sbjct 186 GQIGAGEQTDGELNALGWLDAWFARYIESRRHEPRNDVLTQMAAATYPDGTTPEVTSVVR 245 Query 268 MVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYR 326 T LFAAG E+TA LLG+A+ +A P +Q+++R + E + IEETLR E P + +R Sbjct 246 AATFLFAAGQETTARLLGAALKFIAENPGLQEEIREHRERIPDLIEETLRVESPVKADFR 305 Query 327 HVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCV 386 R TT+ E+PA + ++LL GAANRDP QFE P EFR+ R + HI+FG+G H C Sbjct 306 LARRTTTIGDVEVPAGTPVMLLNGAANRDPRQFECPAEFRISRRNVRQHIAFGRGIHSCP 365 Query 387 GAALARLEARIVLRLLLDRTSVIEAAD 413 G LAR+E RI L +LDRT I ++ Sbjct 366 GGPLARVEGRISLERILDRTRDIRISE 392 >gi|108797599|ref|YP_637796.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119866686|ref|YP_936638.1| cytochrome P450 [Mycobacterium sp. KMS] gi|126433222|ref|YP_001068913.1| cytochrome P450 [Mycobacterium sp. JLS] gi|108768018|gb|ABG06740.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119692775|gb|ABL89848.1| cytochrome P450 [Mycobacterium sp. KMS] gi|126233022|gb|ABN96422.1| cytochrome P450 [Mycobacterium sp. JLS] Length=423 Score = 196 bits (499), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 138/435 (32%), Positives = 209/435 (49%), Gaps = 46/435 (10%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT + + F + DPYP+ +MR AG V R V G+D +G PE FS Sbjct 1 MTTLESLDFFHDETLIDDPYPVLNQMREAGPVLREPVHGVMIVTGYDEALAVLGDPETFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGP---------------THVLATADDPAHAVHRKLV 135 S + T P ++ L G + L + D P H HR L+ Sbjct 61 S----CNSVTGPIPGFPVPLEGLDGAEVSALIDAHREELPFSDQLPSFDPPKHTAHRSLL 116 Query 136 LRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIA 195 R + KR++ E+F ADR+ + G E++ +A + ++VVA+L+G+P+ D A Sbjct 117 SRLITPKRLKENEEFMWTLADRVLDPFLAQGGGEFIRQVAGKFALLVVADLLGVPEEDHA 176 Query 196 QLVKWGYAATQLLEG---LVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELAT 252 +L T L G L D V L L + D PRD+++ +A Sbjct 177 EL-------TARLTGDMALGSTDDTVMEHAPLEYLYTRFTDYIDDRRKAPRDDIMTGMAL 229 Query 253 ACASGELDTLTAQVMMV-----TLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELL 307 A D T +V+ V LF+AG E+T LL +A+ ++A ++Q +R +P+ + Sbjct 230 ATFP---DGSTPEVIDVVRVAANLFSAGQETTVRLLSTALQLVAENAELQAALRDSPDKI 286 Query 308 GAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRL 367 F EE LR+E P +G +R R TTL G E+PA + L++ GAANRDP F+ P F Sbjct 287 SNFNEECLRFESPIKGDFRLARATTTLGGVEIPAGTTLMVHLGAANRDPRHFDNPNVFDP 346 Query 368 DRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVG---------GWL 418 DR + HI FG+G H C+GA LAR E R++L LL RT+ I + ++ Sbjct 347 DRPNARRHIGFGRGVHSCIGAPLARAEGRVLLERLLARTTAITIDEAAHGPAGARRYAYV 406 Query 419 PSILVRRIERLELAV 433 P+ ++R + L + V Sbjct 407 PTYVLRGLTDLHVKV 421 >gi|41406766|ref|NP_959602.1| hypothetical protein MAP0668 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395116|gb|AAS02985.1| hypothetical protein MAP_0668 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461104|gb|EGO39983.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=426 Score = 196 bits (499), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 136/397 (35%), Positives = 202/397 (51%), Gaps = 30/397 (7%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT + F A+ QDPY ++ +R G V R + AV G+ V A E FS Sbjct 1 MTDLAQVDYFTDADVAQDPYDYWDYLREQGPVFREPHYGVVAVTGYQEVQAAFKDVESFS 60 Query 91 SNLTATMTYTAEGTAKPFEMDPLGGPTHVLATA--------------DDPAHAVHRKLVL 136 + G P P G L A D P H R L+ Sbjct 61 A------VNAIGGPFPPLPFTPEGDDISELIEAHRHEFPIFEHMVVMDPPEHDKARSLLG 114 Query 137 RHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQ 196 R L +R++ + + Q ADR + + + +G E++ A + +A+L+G+PD D Q Sbjct 115 RLLTPRRLQENKDYIWQLADRQFDEFIANGHCEFLSEYAKPFATLAIADLLGVPDEDRPQ 174 Query 197 LVKWGYA--ATQLLEGLVENDQLVAAGVALME--LSGYIFEQFDRAAADPRDNLLGELAT 252 + + A A G ++++ + + + ++ SGYI ++ +R PRD++L LAT Sbjct 175 IRRNLGAGNAPGARVGALDHEPVGSNPLQYLDDLFSGYIADRRER----PRDDVLTGLAT 230 Query 253 AC-ASGELDTLTAQVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAF 310 A G L V T LFAAG E+ LL +AV +L +P++Q ++RA+ L+G F Sbjct 231 ATYPDGSTPPLLEVVRPATFLFAAGQETVTKLLSAAVQVLGDQPELQARLRADRGLIGPF 290 Query 311 IEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRA 370 IEE LR + P + +R R TTL G +PA + ++L GAANRDP +FE P EFR+DR Sbjct 291 IEEALRMQSPTKVDFRLARKTTTLGGVHIPAGTVIMLCLGAANRDPRKFENPNEFRIDRK 350 Query 371 GGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTS 407 + HI+FG+G H C GA LAR+E +I + LLDRTS Sbjct 351 NVREHIAFGRGIHTCAGAPLARVEGQITINRLLDRTS 387 >gi|296169455|ref|ZP_06851075.1| unspecific monooxygenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895721|gb|EFG75416.1| unspecific monooxygenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=426 Score = 196 bits (499), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 143/429 (34%), Positives = 219/429 (52%), Gaps = 37/429 (8%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT D + F A+ QDPY ++ +R G V R + AV G+ V A + FS Sbjct 1 MTEPADVDYFTDADIAQDPYSYWDYLRDQGPVFREPHYGVVAVTGYQEVLAAFKDADSFS 60 Query 91 SNLTATMTYTAEGTAKPF--EMDPLGGPTHV----------LATADDPAHAVHRKLVLRH 138 A PF E D +G + D P H R L+ R Sbjct 61 ----AVNAIGGPFPPLPFVPEGDDIGEQIEAHRHEFPIFEHMVVMDPPEHDKARSLLGRL 116 Query 139 LAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPD---PDIA 195 L +R++ + + Q ADR + + + +G E++G + +A+L+G+PD P+I Sbjct 117 LTPRRLQENKDYIWQLADRQFDEFIANGHCEFLGDYGKPFATLAIADLLGVPDEDRPEIR 176 Query 196 QLVKWGYAATQLLEGLVENDQLVAAGVALME--LSGYIFEQFDRAAADPRDNLLGELATA 253 + + G A + G ++++ + + + ++ SGYI E+ ++ PR+++L LATA Sbjct 177 RNLGAGNAPGARV-GALDHEPVGSNPLQYLDDLFSGYIAERREQ----PREDVLTGLATA 231 Query 254 C-ASGELDTLTAQVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFI 311 G L V T LFAAG E+ LL SAV +L +P++Q+++RAN +L+G FI Sbjct 232 TYPDGSTPPLLEVVRPATFLFAAGQETVTKLLSSAVQVLGDQPELQERLRANRDLIGPFI 291 Query 312 EETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAG 371 EE LR + P + +R R TTL G + A + ++L GAANRDP +FE P EFRLDR Sbjct 292 EEALRMQSPTKVDFRLARKTTTLGGVRIRAGTVIMLCLGAANRDPRKFENPNEFRLDRKN 351 Query 372 GKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTS--VIEAADVGG-------WLPSIL 422 + HI+FG+G H C GA LAR+E ++ + LLDRT VI A G + P+ L Sbjct 352 VREHIAFGRGIHTCAGAPLARVEGQVTINRLLDRTRDLVISEAKHGAPARRQYHYEPTFL 411 Query 423 VRRIERLEL 431 +R + L + Sbjct 412 LRGLTELHI 420 >gi|342860318|ref|ZP_08716969.1| hypothetical protein MCOL_15626 [Mycobacterium colombiense CECT 3035] gi|342131973|gb|EGT85214.1| hypothetical protein MCOL_15626 [Mycobacterium colombiense CECT 3035] Length=426 Score = 194 bits (494), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 136/424 (33%), Positives = 221/424 (53%), Gaps = 27/424 (6%) Query 31 MTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFS 90 MT D + F A+ Q+PY ++ +R G V R + AV G+ V A FS Sbjct 1 MTELADVDYFTDADIAQEPYAYWDYLRGQGPVFREPHYGVVAVTGYQEVQAAFKDVASFS 60 Query 91 S-----NLTATMTYTAEG--TAKPFEMDPLGGPT-HVLATADDPAHAVHRKLVLRHLAAK 142 + + +T EG + E P + D P H R L+ R L + Sbjct 61 AVNAIGGPFPPLPFTPEGDDISDQIEAHRHEFPIFEHMVVMDPPEHEKARSLLGRLLTPR 120 Query 143 RIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGY 202 R++ + + Q ADR + + + +G E++G A + +A+L+G+PD D A++ + Sbjct 121 RLQENKDYIWQLADRQFDEFIANGQCEFLGEYAKPFATLAIADLLGVPDEDRAEIRRNLG 180 Query 203 A--ATQLLEGLVENDQLVAAGVALME--LSGYIFEQFDRAAADPRDNLLGELATAC-ASG 257 A A G ++++ + + + ++ S YI ++ +R PR+++L LATA G Sbjct 181 AGNAPGARVGALDHEPVGSNPLQYLDDLFSAYITDRRER----PREDVLTGLATATYPDG 236 Query 258 ELDTLTAQVMMVT-LFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLR 316 + L V T LFAAG E+ LL +AV +L +P++Q ++RA+ L+G+FIEE LR Sbjct 237 SIPPLLEVVRPATFLFAAGQETVTKLLSAAVQVLGDQPELQARLRADRSLIGSFIEEALR 296 Query 317 YEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHI 376 + P + +R R TTL G +PA + ++L GAANRDP +FE+P EF++DR + HI Sbjct 297 MQSPTKVDFRLARKTTTLGGVHIPAGTVIMLCLGAANRDPRKFESPNEFQVDRKNVREHI 356 Query 377 SFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGG---------WLPSILVRRIE 427 +FG+G H C GA LAR+E +I + LLDRT I ++ + P+ L+R ++ Sbjct 357 AFGRGIHTCAGAPLARVEGQITVNRLLDRTRDIRISEAKHGAAPNRDYRYEPTFLLRGLK 416 Query 428 RLEL 431 L + Sbjct 417 ELHI 420 >gi|158316454|ref|YP_001508962.1| cytochrome P450 [Frankia sp. EAN1pec] gi|158111859|gb|ABW14056.1| cytochrome P450 [Frankia sp. EAN1pec] Length=444 Score = 193 bits (491), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 141/421 (34%), Positives = 211/421 (51%), Gaps = 30/421 (7%) Query 36 DANTFFGAES-VQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLT 94 +A FF E+ V DPYP + +R V R + D V G++ E E FSS ++ Sbjct 5 EAMDFFRDETLVADPYPYLDALRRKCPVQRERHHDVVMVTGYEEAVEVFHDSEAFSSCVS 64 Query 95 ATMTYTAEGTAKPFEMDPLGG---------PTH-VLATADDPAHAVHRKLVLRHLAAKRI 144 T + G P + D + P + L T D P H HR L++R + KR+ Sbjct 65 VTGPFP--GFPVPLDGDDVSALIERHRHELPMNDQLPTMDPPTHTDHRALLMRLITPKRL 122 Query 145 RVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAA 204 + E ADR+ + G E++ A ++V+A+L+G+P+ D + + Sbjct 123 KENEALMWDLADRMLDPFLTPGEGEFISGFAGPFTLLVIADLLGVPEEDQDEFLDKLQRQ 182 Query 205 TQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTA 264 G+ A L L G + +PR ++L LA A D T Sbjct 183 PAQTGGVGGTGAETLAHSPLEFLYGKFTGYIEDRRRNPRADVLTGLAGATFP---DGSTP 239 Query 265 QVMMV-----TLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEP 319 +V+ V LF+AG E+T LL SA+ ILA RPD+Q+Q+R E + AFIEETLR+E Sbjct 240 EVIDVVRVAANLFSAGQETTVRLLSSALKILAERPDLQRQLRVERERIPAFIEETLRWES 299 Query 320 PFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFG 379 P +G +R R T+ G +LPA + ++++ GAANRDP +FE P F + R+ + H++FG Sbjct 300 PVKGDFRLSRVPVTVGGVQLPAGTTVMVVNGAANRDPRRFENPETFDVARSNARQHLAFG 359 Query 380 KGAHFCVGAALARLEARIVLRLLLDRTSVIEAAD-VGG--------WLPSILVRRIERLE 430 +G H C GA LAR EAR L LLDRT+ I + V G ++P+ ++R + L Sbjct 360 RGIHSCPGAPLARAEARASLERLLDRTTDIRVNERVHGPAGNRRYEYMPTFILRGLTALH 419 Query 431 L 431 L Sbjct 420 L 420 >gi|41406825|ref|NP_959661.1| hypothetical protein MAP0727 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395175|gb|AAS03044.1| hypothetical protein MAP_0727 [Mycobacterium avium subsp. paratuberculosis K-10] Length=424 Score = 193 bits (490), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 133/413 (33%), Positives = 207/413 (51%), Gaps = 25/413 (6%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F G+E +++PYP YE +R V + ++ + + GWD + E +SS ++ T + Sbjct 11 FRGSELIENPYPYYEALRQRCPVTKESHHNVTMITGWDEACAVLNDAETWSSCISVTGPF 70 Query 100 TAEGTAKPFEMDPLGG---------P-THVLATADDPAHAVHRKLVLRHLAAKRIRVMEQ 149 G P E D + P + L T D P H HR L++R + KR++ E Sbjct 71 P--GFPVPLEGDDVTELIERHRDELPFSDQLPTLDPPTHTNHRSLLMRLITPKRLKENED 128 Query 150 FTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLE 209 AD+ + G E++ A ++V+A+L+G+P+ D + VK + Sbjct 129 AMWVLADQALDTFLAPGHGEFIKGFAGPFTLLVIADLLGVPEEDRDKFVKGIRQHSGGGV 188 Query 210 GLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMV 269 G + L A L L G F+ PR+++L LATA V V Sbjct 189 GGTGEETL--AHSPLEFLYGLFFDYVRDRRRQPREDVLTGLATATYPDGSIPEVEDVARV 246 Query 270 --TLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRH 327 +F+AG E+T LLG+A+ L RPDIQ Q+R + L+ FIEE+LR+E P +G +R Sbjct 247 ASNVFSAGQETTVRLLGAALQTLGERPDIQAQLRKDRSLIPNFIEESLRHESPVKGDFRL 306 Query 328 VRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVG 387 R T+ G +LPA + ++++ AANRDP +F+ P F R + HISFG+G H C G Sbjct 307 NRRPVTVGGVDLPAGTTVMVVQAAANRDPRRFDDPATFDPARKNARQHISFGRGIHSCPG 366 Query 388 AALARLEARIVLRLLLDRTSVIE-AADVGG--------WLPSILVRRIERLEL 431 A LAR E R+ + LLDRT+ I ++ G ++P+ ++R + L L Sbjct 367 APLARAETRVAIERLLDRTTDIRINENIHGPANDRRYQYVPTYILRGLTELHL 419 >gi|254818629|ref|ZP_05223630.1| cytochrome p450 [Mycobacterium intracellulare ATCC 13950] Length=424 Score = 192 bits (488), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 140/413 (34%), Positives = 205/413 (50%), Gaps = 25/413 (6%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F G+E + DPYP YE +R V R ++ D + GWD + E +SS ++ T + Sbjct 11 FRGSELIADPYPYYEALRQRCPVTRESHHDVTMITGWDEACAVLNDAETWSSCISVTGPF 70 Query 100 TAEGTAKPFEMDPLGG---------P-THVLATADDPAHAVHRKLVLRHLAAKRIRVMEQ 149 G P E D + P + L T D P H HR L++R + KR++ E Sbjct 71 P--GFPVPLEGDDVTELIERHRDELPFSDQLPTLDPPTHTNHRSLLMRLITPKRLKENED 128 Query 150 FTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLE 209 AD+ + + G EW+ A ++V+A+L+G+P D + VK + Sbjct 129 AMWALADQALDEFLAPGHGEWIKGFAGPFTLLVIADLLGVPMEDRDKFVKGIREHSGGGV 188 Query 210 GLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMV 269 G + L A L L G + +PRD++L LATA V V Sbjct 189 GGTGKESL--AHSPLEFLYGLFSDYVRDRRREPRDDVLTGLATATFPDGSIPEVEDVARV 246 Query 270 --TLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRH 327 +F+AG E+T LLG+A+ L RPD+Q Q+R + L+ FIEE+LR+E P +G +R Sbjct 247 AANVFSAGQETTVRLLGAALQTLGERPDVQAQLRKDRSLIPNFIEESLRHESPVKGDFRM 306 Query 328 VRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVG 387 R T+ G +LPA S ++++ AANRDP +FE P F R + HISFG+G H C G Sbjct 307 NRVPATVGGVDLPAGSTVMIVQAAANRDPRRFEDPATFDPARKNARQHISFGRGIHSCPG 366 Query 388 AALARLEARIVLRLLLDRTSVIE-AADVGG--------WLPSILVRRIERLEL 431 A LAR E R+ L LLDRT+ I D G ++P+ ++R + L L Sbjct 367 APLARAETRVALERLLDRTTDIRINEDKHGPANDRRYQYVPTYILRGLTELHL 419 >gi|342860392|ref|ZP_08717043.1| cytochrome p450 [Mycobacterium colombiense CECT 3035] gi|342132047|gb|EGT85288.1| cytochrome p450 [Mycobacterium colombiense CECT 3035] Length=423 Score = 191 bits (486), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 139/413 (34%), Positives = 206/413 (50%), Gaps = 26/413 (6%) Query 40 FFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTY 99 F G E +++PYP YE +R V R ++ D + GWD + E +SS ++ T + Sbjct 11 FRGTELIENPYPYYEALRERCPVTRESHHDVTMITGWDEACAVLNDAETWSSCISVTGPF 70 Query 100 TAEGTAKPFEMDPLGG---------P-THVLATADDPAHAVHRKLVLRHLAAKRIRVMEQ 149 G P E D + P + L T D P H HR L++R + KR++ E Sbjct 71 P--GFPVPIEGDDITELIEQHRDELPFSDQLPTLDPPTHTNHRSLMMRLITPKRLKENED 128 Query 150 FTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLE 209 AD+ D + G EW+ A ++V+A+L+G+P D + VK G A Sbjct 129 AMWALADQALDDFLAPGRGEWIKGFAGPFTLLVIADLLGVPMEDRDKFVK-GIAEHAGGG 187 Query 210 GLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATAC-ASGEL-DTLTAQVM 267 L A L L G + +PRD++L LATA G + D + Sbjct 188 IGGTKGSL--AHSPLEFLYGLFSDYVRDRRREPRDDVLTGLATATFPDGSVPDVEDVARV 245 Query 268 MVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRH 327 +F+AG E+T LLG+++ L RPDIQ Q+R + L+ FIEE+LR+E P +G +R Sbjct 246 AANVFSAGQETTVRLLGASLQTLGERPDIQAQLRKDRSLIPNFIEESLRHESPVKGDFRL 305 Query 328 VRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVG 387 R + G ELPA + ++++ AANRDP +FE P F R + HISFG+G H C G Sbjct 306 NRRPVNIGGVELPAGTTVMIVQAAANRDPRRFEDPATFDPARKNARQHISFGRGIHSCPG 365 Query 388 AALARLEARIVLRLLLDRTSVIEAAD-VGG--------WLPSILVRRIERLEL 431 A LAR E R+ + LLDRT+ I + V G ++P+ ++R + L L Sbjct 366 APLARAETRVAIERLLDRTTDIRIDEKVHGPANDRRYQYVPTYILRGLTELHL 418 Lambda K H 0.321 0.135 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 885232741974 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40