BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1785c Length=393 Score E Sequences producing significant alignments: (Bits) Value gi|15608923|ref|NP_216301.1| cytochrome P450 143 [Mycobacterium ... 793 0.0 gi|254231973|ref|ZP_04925300.1| cytochrome P450 143 cyp143 [Myco... 793 0.0 gi|15841253|ref|NP_336290.1| P450 heme-thiolate protein [Mycobac... 793 0.0 gi|289443252|ref|ZP_06432996.1| cytochrome P450 143 cyp143 [Myco... 792 0.0 gi|289745783|ref|ZP_06505161.1| cytochrome P450 143 [Mycobacteri... 791 0.0 gi|260667411|gb|ACX47918.1| cytochrome P450 143A1 [Mycobacterium... 791 0.0 gi|340626797|ref|YP_004745249.1| putative cytochrome P450 143 CY... 790 0.0 gi|240172018|ref|ZP_04750677.1| putative cytochrome P450 143 [My... 692 0.0 gi|183982673|ref|YP_001850964.1| cytochrome P450 143A4 Cyp143A4 ... 613 2e-173 gi|118618474|ref|YP_906806.1| cytochrome P450 143A4 Cyp143A4 [My... 612 3e-173 gi|254820288|ref|ZP_05225289.1| P450 heme-thiolate protein [Myco... 603 1e-170 gi|342861313|ref|ZP_08717961.1| P450 heme-thiolate protein [Myco... 603 2e-170 gi|296164776|ref|ZP_06847338.1| cytochrome P450 Cyp143A4 [Mycoba... 591 5e-167 gi|118465559|ref|YP_882117.1| P450 heme-thiolate protein [Mycoba... 587 1e-165 gi|41407601|ref|NP_960437.1| hypothetical protein MAP1503c [Myco... 557 1e-156 gi|296170415|ref|ZP_06852003.1| P450 heme-thiolate protein [Myco... 549 3e-154 gi|240170525|ref|ZP_04749184.1| cytochrome P450 143A4 Cyp143A4 [... 546 2e-153 gi|126436732|ref|YP_001072423.1| cytochrome P450 [Mycobacterium ... 525 4e-147 gi|118466259|ref|YP_881740.1| cytochrome P450 143 [Mycobacterium... 490 2e-136 gi|145222354|ref|YP_001133032.1| cytochrome P450 [Mycobacterium ... 472 4e-131 gi|126437368|ref|YP_001073059.1| cytochrome P450 [Mycobacterium ... 470 2e-130 gi|108801385|ref|YP_641582.1| cytochrome P450 [Mycobacterium sp.... 466 3e-129 gi|183982641|ref|YP_001850932.1| cytochrome P450 143A3 Cyp143A3 ... 462 3e-128 gi|118618484|ref|YP_906816.1| cytochrome P450 143A3 Cyp143A3 [My... 461 8e-128 gi|120405932|ref|YP_955761.1| cytochrome P450 [Mycobacterium van... 459 3e-127 gi|333992054|ref|YP_004524668.1| cytochrome P450 [Mycobacterium ... 452 4e-125 gi|289761935|ref|ZP_06521313.1| cytochrome P450 143 cyp143 [Myco... 347 3e-93 gi|111222778|ref|YP_713572.1| putative cytochrome P450 [Frankia ... 329 4e-88 gi|126436602|ref|YP_001072293.1| cytochrome P450 [Mycobacterium ... 315 1e-83 gi|254820065|ref|ZP_05225066.1| cytochrome P450 [Mycobacterium i... 314 1e-83 gi|118463806|ref|YP_881849.1| cytochrome P450 [Mycobacterium avi... 314 2e-83 gi|118465871|ref|YP_881169.1| cytochrome P450 126 [Mycobacterium... 311 9e-83 gi|111224855|ref|YP_715649.1| cytochrome P450 [Frankia alni ACN1... 308 1e-81 gi|118466761|ref|YP_881172.1| cytochrome P450 [Mycobacterium avi... 308 1e-81 gi|126436607|ref|YP_001072298.1| cytochrome P450 [Mycobacterium ... 301 1e-79 gi|302546892|ref|ZP_07299234.1| P450 heme-thiolate protein [Stre... 244 2e-62 gi|296170209|ref|ZP_06851802.1| P450 heme-thiolate protein [Myco... 236 4e-60 gi|118465105|ref|YP_881420.1| cytochrome P450 superfamily protei... 231 2e-58 gi|158316356|ref|YP_001508864.1| cytochrome P450 [Frankia sp. EA... 231 2e-58 gi|254774922|ref|ZP_05216438.1| cytochrome P450 superfamily prot... 230 4e-58 gi|336461837|gb|EGO40693.1| cytochrome P450 [Mycobacterium avium... 229 4e-58 gi|296166114|ref|ZP_06848559.1| cytochrome P450 CYP254 [Mycobact... 229 5e-58 gi|41408077|ref|NP_960913.1| hypothetical protein MAP1979 [Mycob... 228 1e-57 gi|297153658|gb|ADI03370.1| putative cytochrome P450 [Streptomyc... 224 2e-56 gi|240171228|ref|ZP_04749887.1| cytochrome P450 superfamily prot... 224 2e-56 gi|342857247|ref|ZP_08713903.1| cytochrome P450 superfamily prot... 219 5e-55 gi|111017415|ref|YP_700387.1| cytochrome P450 [Rhodococcus josti... 214 2e-53 gi|334344633|ref|YP_004553185.1| Camphor 5-monooxygenase [Sphing... 210 4e-52 gi|111017445|ref|YP_700417.1| cytochrome P450 [Rhodococcus josti... 208 1e-51 gi|111223235|ref|YP_714029.1| putative camphor 5-monooxygenase [... 207 2e-51 >gi|15608923|ref|NP_216301.1| cytochrome P450 143 [Mycobacterium tuberculosis H37Rv] gi|31792973|ref|NP_855466.1| cytochrome P450 143 [Mycobacterium bovis AF2122/97] gi|121637686|ref|YP_977909.1| putative cytochrome P450 143 cyp143 [Mycobacterium bovis BCG str. Pasteur 1173P2] 58 more sequence titles Length=393 Score = 793 bits (2049), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 >gi|254231973|ref|ZP_04925300.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis C] gi|124601032|gb|EAY60042.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis C] Length=426 Score = 793 bits (2049), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 34 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 93 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 94 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 153 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 154 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 213 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 214 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 273 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 274 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 333 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 334 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 393 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 394 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 426 >gi|15841253|ref|NP_336290.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|13881479|gb|AAK46104.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] Length=426 Score = 793 bits (2049), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 34 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 93 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 94 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 153 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 154 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 213 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 214 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 273 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 274 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 333 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 334 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 393 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 394 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 426 >gi|289443252|ref|ZP_06432996.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T46] gi|289569850|ref|ZP_06450077.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T17] gi|289750352|ref|ZP_06509730.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T92] gi|289416171|gb|EFD13411.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T46] gi|289543604|gb|EFD47252.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T17] gi|289690939|gb|EFD58368.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T92] Length=393 Score = 792 bits (2045), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/393 (99%), Positives = 393/393 (100%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPL+EIEVLGLSHLLILAGLDTVTAA Sbjct 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLNEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 >gi|289745783|ref|ZP_06505161.1| cytochrome P450 143 [Mycobacterium tuberculosis 02_1987] gi|289757887|ref|ZP_06517265.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis T85] gi|294996696|ref|ZP_06802387.1| P450 heme-thiolate protein [Mycobacterium tuberculosis 210] 7 more sequence titles Length=393 Score = 791 bits (2043), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/393 (99%), Positives = 392/393 (99%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHW FGGGPHRCLGSHLARLELTLLVGEWL Sbjct 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWAFGGGPHRCLGSHLARLELTLLVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 >gi|260667411|gb|ACX47918.1| cytochrome P450 143A1 [Mycobacterium bovis] Length=393 Score = 791 bits (2042), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/393 (99%), Positives = 392/393 (99%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG Sbjct 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALK LPLRWS Sbjct 361 NQIPDFELAPDYAPEIRFPSKSFALKTLPLRWS 393 >gi|340626797|ref|YP_004745249.1| putative cytochrome P450 143 CYP143 [Mycobacterium canettii CIPT 140010059] gi|340004987|emb|CCC44135.1| putative cytochrome P450 143 CYP143 [Mycobacterium canettii CIPT 140010059] Length=393 Score = 790 bits (2039), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/393 (99%), Positives = 392/393 (99%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA Sbjct 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD Sbjct 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTE VTVGGMTLPAG Sbjct 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTELVTVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL Sbjct 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 >gi|240172018|ref|ZP_04750677.1| putative cytochrome P450 143 [Mycobacterium kansasii ATCC 12478] Length=393 Score = 692 bits (1785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/393 (86%), Positives = 359/393 (92%), Gaps = 0/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 M+T AG+FYLPRLEYSTLPMA DRG+GWKTLRDAGPVVFMNGWYYLTRREDVLAAL Sbjct 1 MSTTEGGQAGAFYLPRLEYSTLPMASDRGLGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RN K FSSR+ALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAAL+K P+L HT+A Sbjct 61 RNTKAFSSREALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALAKVRPTLLTHTIA 120 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MIDA+A RGECEAMAD ANLFPFQLFLVLYGLP+ DRDRLI WKDAVIAMSDRP+PTEAD Sbjct 121 MIDALAPRGECEAMADFANLFPFQLFLVLYGLPVADRDRLIAWKDAVIAMSDRPYPTEAD 180 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 AA REL EYL + ER++NPGPDVLSQV IG+DPLSEIEVLGLSHLLILAGLDTVTAA Sbjct 181 AAATRELFEYLAQAITERKQNPGPDVLSQVLIGDDPLSEIEVLGLSHLLILAGLDTVTAA 240 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 VGF LLELARRP+LRA+LRDNPKQIRVFIEEIVRLEPSAPVAPR+TT V VGGMTLPAG Sbjct 241 VGFCLLELARRPELRALLRDNPKQIRVFIEEIVRLEPSAPVAPRITTRVVEVGGMTLPAG 300 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 SPVRLCMAA+NRDG+DAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTL+VGEWL Sbjct 301 SPVRLCMAAINRDGTDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLVVGEWL 360 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 +IPDF LAP Y PEI+FPSKSFALK LPLRW Sbjct 361 KRIPDFGLAPGYTPEIQFPSKSFALKTLPLRWG 393 >gi|183982673|ref|YP_001850964.1| cytochrome P450 143A4 Cyp143A4 [Mycobacterium marinum M] gi|183175999|gb|ACC41109.1| cytochrome P450 143A4 Cyp143A4 [Mycobacterium marinum M] Length=391 Score = 613 bits (1581), Expect = 2e-173, Method: Compositional matrix adjust. Identities = 299/394 (76%), Positives = 338/394 (86%), Gaps = 4/394 (1%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 M+TPGE A SFYLPRLEYSTLP+A DR VGW TLRDAGPVVFMNG YYLTRREDVLAAL Sbjct 1 MSTPGEGSASSFYLPRLEYSTLPLAADRAVGWNTLRDAGPVVFMNGHYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPK+FSSR LQPPGNPLPVVPLAFDPPEHTRYR+ LQPYFSP AL K+ P L RH Sbjct 61 RNPKIFSSR-ILQPPGNPLPVVPLAFDPPEHTRYRKALQPYFSPHALGKSRPVLERHAAE 119 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MI AGRGEC+AMA+ A L+PFQ+FL LYGLPL+DRDR+I WKDA+I D+ + T + Sbjct 120 MIAGFAGRGECDAMAEFARLYPFQVFLDLYGLPLQDRDRVIAWKDAIIG--DKLYLTREE 177 Query 181 VAAAR-ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTA 239 + + ELLEYL + +RR+NPG D+LSQV G +++E+LG+SHLLILAGLDTVTA Sbjct 178 LEVGQLELLEYLNNAIQQRRQNPGSDMLSQVMTGPGEFTDLELLGMSHLLILAGLDTVTA 237 Query 240 AVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPA 299 A+GFSLLELARRPQLR LRDNPK+IRVFIEEIVRLEPSAPVAPR+TT+ V VGGMTLP Sbjct 238 AIGFSLLELARRPQLRTQLRDNPKEIRVFIEEIVRLEPSAPVAPRITTDFVNVGGMTLPP 297 Query 300 GSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEW 359 GS VRLCMAAVNRDGSDAMST+ELVMDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EW Sbjct 298 GSQVRLCMAAVNRDGSDAMSTNELVMDGKVHRHWGFGGGPHRCLGSHLARIELTVIVAEW 357 Query 360 LNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 L Q+PDFELAPDY+PEI FPSK+FALK+LPLRW+ Sbjct 358 LKQLPDFELAPDYSPEIAFPSKTFALKSLPLRWA 391 >gi|118618474|ref|YP_906806.1| cytochrome P450 143A4 Cyp143A4 [Mycobacterium ulcerans Agy99] gi|118570584|gb|ABL05335.1| cytochrome P450 143A4 Cyp143A4 [Mycobacterium ulcerans Agy99] Length=391 Score = 612 bits (1579), Expect = 3e-173, Method: Compositional matrix adjust. Identities = 298/394 (76%), Positives = 338/394 (86%), Gaps = 4/394 (1%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 M+TPGE A SFYLPRLEYSTLP++ DR VGW TLRDAGPVVFMNG YYLTRREDVLAAL Sbjct 1 MSTPGEGSASSFYLPRLEYSTLPLSADRAVGWNTLRDAGPVVFMNGHYYLTRREDVLAAL 60 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPK+FSSR LQPPGNPLPVVPLAFDPPEHTRYR+ LQPYFSP AL K+ P L RH Sbjct 61 RNPKIFSSR-ILQPPGNPLPVVPLAFDPPEHTRYRKALQPYFSPHALGKSRPVLERHAAE 119 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MI AGRGEC+AMA+ A L+PFQ+FL LYGLPL+DRDR+I WKDA+I D+ + T + Sbjct 120 MIAGFAGRGECDAMAEFARLYPFQVFLDLYGLPLQDRDRVIAWKDAIIG--DKLYLTREE 177 Query 181 VAAAR-ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTA 239 + + ELLEYL + +RR+NPG D+LSQV G +++E+LG+SHLLILAGLDTVTA Sbjct 178 LEVGQLELLEYLNNAIQQRRQNPGSDMLSQVMTGPGEFTDLELLGMSHLLILAGLDTVTA 237 Query 240 AVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPA 299 A+GFSLLELARRPQLR LRDNPK+IRVFIEEIVRLEPSAPVAPR+TT+ V VGGMTLP Sbjct 238 AIGFSLLELARRPQLRTQLRDNPKEIRVFIEEIVRLEPSAPVAPRITTDFVNVGGMTLPP 297 Query 300 GSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEW 359 GS VRLCMAAVNRDGSDAMST+ELVMDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EW Sbjct 298 GSQVRLCMAAVNRDGSDAMSTNELVMDGKVHRHWGFGGGPHRCLGSHLARIELTVIVAEW 357 Query 360 LNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 L Q+PDFELAPDY+PEI FPSK+FALK+LPLRW+ Sbjct 358 LKQLPDFELAPDYSPEIAFPSKTFALKSLPLRWA 391 >gi|254820288|ref|ZP_05225289.1| P450 heme-thiolate protein [Mycobacterium intracellulare ATCC 13950] Length=387 Score = 603 bits (1556), Expect = 1e-170, Method: Compositional matrix adjust. Identities = 296/383 (78%), Positives = 333/383 (87%), Gaps = 3/383 (0%) Query 10 GSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSR 69 GSF+LPRL+ LPM+ DR +GWKTLRDAGPVVFMNG YYLTRREDVLAALRNPKVFSS Sbjct 7 GSFHLPRLDVDKLPMSADRALGWKTLRDAGPVVFMNGHYYLTRREDVLAALRNPKVFSS- 65 Query 70 KALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRG 129 LQPPG+PLPV+PLAFDPP+HTRYR+ILQPYFSP ALSK+ P+L RH MI A+AGRG Sbjct 66 TVLQPPGHPLPVLPLAFDPPQHTRYRKILQPYFSPHALSKSRPALERHARDMIGALAGRG 125 Query 130 ECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLE 189 ECE MADLA+L+PFQ+FL LYGLPLEDRDRLI WKD+VIA D+P T+AD+A ++LL+ Sbjct 126 ECEVMADLASLYPFQVFLDLYGLPLEDRDRLIDWKDSVIA--DKPFLTQADMAKGQQLLQ 183 Query 190 YLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELA 249 YL +A+RR+NPG D+LSQV G S+IE+LG+SHLLILAGLDTVTAA+GFSL ELA Sbjct 184 YLVDAIAQRRQNPGSDMLSQVMTGGGDFSDIELLGMSHLLILAGLDTVTAAIGFSLFELA 243 Query 250 RRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAA 309 RRPQLRA LRDNPKQIRVFIEEIVRLEPSAPVAPR+TTE V VGGMTLP G+ VRLCMAA Sbjct 244 RRPQLRAELRDNPKQIRVFIEEIVRLEPSAPVAPRITTEFVEVGGMTLPPGTSVRLCMAA 303 Query 310 VNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELA 369 VNRD SD MST+EL MDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EWLNQIPDFEL Sbjct 304 VNRDDSDPMSTNELNMDGKVHRHWGFGGGPHRCLGSHLARIELTVIVAEWLNQIPDFELP 363 Query 370 PDYAPEIRFPSKSFALKNLPLRW 392 DY+P I +PSKSFALK LPLRW Sbjct 364 ADYSPVINYPSKSFALKELPLRW 386 >gi|342861313|ref|ZP_08717961.1| P450 heme-thiolate protein [Mycobacterium colombiense CECT 3035] gi|342131213|gb|EGT84494.1| P450 heme-thiolate protein [Mycobacterium colombiense CECT 3035] Length=387 Score = 603 bits (1554), Expect = 2e-170, Method: Compositional matrix adjust. Identities = 291/387 (76%), Positives = 335/387 (87%), Gaps = 3/387 (0%) Query 6 EDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKV 65 E GSFYLPRL+++TLPM DRGVGWKTLRDAGPVVFMNG YY+TRREDVLAALRN KV Sbjct 3 EGQQGSFYLPRLDFATLPMGADRGVGWKTLRDAGPVVFMNGHYYITRREDVLAALRNTKV 62 Query 66 FSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAI 125 FSS LQPPG+PLPV+PLAFDPP+HTRYR+ILQPYFSP ALSK+ P L RH MIDA+ Sbjct 63 FSS-TVLQPPGHPLPVLPLAFDPPQHTRYRQILQPYFSPHALSKSRPVLERHAGEMIDAL 121 Query 126 AGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAAR 185 AGRGECE MAD ANL+PFQ+FL LYGLP+EDRDRLI WKDAV+ S++P T++D+ + Sbjct 122 AGRGECEVMADFANLYPFQVFLDLYGLPVEDRDRLIDWKDAVV--SEKPFITQSDIEKSE 179 Query 186 ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 +LL+YL +A+RRRNPG D+LS+V G+ +++E+LG+SHLLILAGLDTVTAA+GFSL Sbjct 180 QLLQYLADAIAQRRRNPGSDMLSKVITGKGNFTDLELLGMSHLLILAGLDTVTAAIGFSL 239 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 ELARRPQLR LRDNPKQIRVFIEEIVRLEPSAPVAPR+TT+ V VGGMTLP G+ VRL Sbjct 240 YELARRPQLRKQLRDNPKQIRVFIEEIVRLEPSAPVAPRITTKYVEVGGMTLPPGTSVRL 299 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 CMAAVNRD SDAMST+EL MDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EWL++IPD Sbjct 300 CMAAVNRDDSDAMSTNELNMDGKVHRHWGFGGGPHRCLGSHLARIELTVVVAEWLSRIPD 359 Query 366 FELAPDYAPEIRFPSKSFALKNLPLRW 392 FEL Y+PEI +PSKSFALK LPLRW Sbjct 360 FELPEGYSPEINYPSKSFALKALPLRW 386 >gi|296164776|ref|ZP_06847338.1| cytochrome P450 Cyp143A4 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899877|gb|EFG79321.1| cytochrome P450 Cyp143A4 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=434 Score = 591 bits (1524), Expect = 5e-167, Method: Compositional matrix adjust. Identities = 284/393 (73%), Positives = 331/393 (85%), Gaps = 3/393 (0%) Query 1 MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAAL 60 MTTPG G+F+LPRL+Y LPMAVDRGVGWKTLRDAGPVVFMNG YY+TRREDVLAAL Sbjct 45 MTTPGGGQYGTFHLPRLDYEKLPMAVDRGVGWKTLRDAGPVVFMNGHYYITRREDVLAAL 104 Query 61 RNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVA 120 RNPKVFSS LQPPG+PLPVVPLAFDPP+HTRYR++LQP+FSP LS + P L RH Sbjct 105 RNPKVFSS-TILQPPGHPLPVVPLAFDPPQHTRYRKVLQPFFSPHGLSASRPVLERHAAE 163 Query 121 MIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD 180 MI A+A +G+CE MAD A L+PFQ+F+ LYGLPL DRDRLIGWKDAV+ D+P+ T D Sbjct 164 MIGALAAQGKCEVMADFARLYPFQVFMDLYGLPLADRDRLIGWKDAVVG--DKPYLTPDD 221 Query 181 VAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAA 240 + R LL YL ++ +RR++PG D+LS++ + S++E+LG+SHLLILAGLDTVTAA Sbjct 222 LEQGRHLLAYLVDVIQQRRQSPGSDMLSRIMASDGDFSDVELLGMSHLLILAGLDTVTAA 281 Query 241 VGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAG 300 +GF LLELARRPQLR +LRD+P+QIRVF+EEIVRLEPSAPVAPRVTT+ V +GGMTLP+G Sbjct 282 IGFCLLELARRPQLRDLLRDDPRQIRVFVEEIVRLEPSAPVAPRVTTQVVEIGGMTLPSG 341 Query 301 SPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWL 360 + VRLCMAAVNRD SDA S +ELVMDGKVHRHWGFGGGPHRCLGSHL R+ELT++VGEWL Sbjct 342 TSVRLCMAAVNRDDSDATSVNELVMDGKVHRHWGFGGGPHRCLGSHLGRIELTVVVGEWL 401 Query 361 NQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 QIPDF+L DYAPEI FPSKSFALK LPLRW Sbjct 402 RQIPDFDLPADYAPEINFPSKSFALKELPLRWG 434 >gi|118465559|ref|YP_882117.1| P450 heme-thiolate protein [Mycobacterium avium 104] gi|254775405|ref|ZP_05216921.1| P450 heme-thiolate protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118166846|gb|ABK67743.1| P450 heme-thiolate protein [Mycobacterium avium 104] gi|336457649|gb|EGO36653.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=387 Score = 587 bits (1513), Expect = 1e-165, Method: Compositional matrix adjust. Identities = 284/387 (74%), Positives = 328/387 (85%), Gaps = 3/387 (0%) Query 6 EDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKV 65 E G+F+LPRL+++TLPM+VDRG+GWKTLRDAGPVVFMNG YYLTRREDVLAALRNPKV Sbjct 3 EGQYGTFHLPRLDFATLPMSVDRGLGWKTLRDAGPVVFMNGHYYLTRREDVLAALRNPKV 62 Query 66 FSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAI 125 FSS LQPPG+PLPV+PLAFDPP+HTRYR+ILQPYFSP AL K+ P L RH MI A+ Sbjct 63 FSS-TVLQPPGHPLPVLPLAFDPPQHTRYRKILQPYFSPHALGKSRPVLERHAAEMIAAL 121 Query 126 AGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAAR 185 A RGECE MAD A+L+PFQ+F+ LYGLPL+DRDRL+ WK+AV+ ++P TE+DV + Sbjct 122 ADRGECEVMADFAHLYPFQVFMDLYGLPLQDRDRLLDWKNAVVG--EKPFVTESDVEKSE 179 Query 186 ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 +LL YL +A+RR++PG D+LSQV GE ++IE+LG+SHLLILAGLDTVTAA+GFSL Sbjct 180 QLLAYLADAIAQRRQHPGTDMLSQVMTGEGNFTDIELLGMSHLLILAGLDTVTAAIGFSL 239 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 ELARRPQLR LRDNPKQ RVFIEEIVRLEPSAPVAPR+TTE V VGGMTLP G+ VRL Sbjct 240 FELARRPQLRKELRDNPKQTRVFIEEIVRLEPSAPVAPRITTEYVEVGGMTLPPGTSVRL 299 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 CMAAVNRD SD+MST+EL MDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EWL QIPD Sbjct 300 CMAAVNRDDSDSMSTNELNMDGKVHRHWGFGGGPHRCLGSHLARIELTVVVAEWLTQIPD 359 Query 366 FELAPDYAPEIRFPSKSFALKNLPLRW 392 FEL Y P I +PSKSFALK LPL W Sbjct 360 FELPDGYEPVINYPSKSFALKELPLHW 386 >gi|41407601|ref|NP_960437.1| hypothetical protein MAP1503c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395954|gb|AAS03820.1| hypothetical protein MAP_1503c [Mycobacterium avium subsp. paratuberculosis K-10] Length=438 Score = 557 bits (1435), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 272/378 (72%), Positives = 316/378 (84%), Gaps = 3/378 (0%) Query 6 EDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKV 65 E G+F+LPRL+++TLPM+VDRG+GWKTLRDAGPVVFMNG YYLTRREDVLAALRNPKV Sbjct 3 EGQYGTFHLPRLDFATLPMSVDRGLGWKTLRDAGPVVFMNGHYYLTRREDVLAALRNPKV 62 Query 66 FSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAI 125 FSS LQPPG+PLPV+PLAFDPP+HTRYR+ILQPYFSP AL K+ P L RH MI A+ Sbjct 63 FSS-TVLQPPGHPLPVLPLAFDPPQHTRYRKILQPYFSPHALGKSRPVLERHAAEMIAAL 121 Query 126 AGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAAR 185 A RGECE MAD A+L+PFQ+F+ LYGLPL+DRDRL+ WK+AV+ ++P TE+DV + Sbjct 122 ADRGECEVMADFAHLYPFQVFMDLYGLPLQDRDRLLDWKNAVVG--EKPFVTESDVEKSE 179 Query 186 ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 +LL YL +A+RR++PG D+LSQV GE ++IE+LG+SHLLILAGLDTVTAA+GFSL Sbjct 180 QLLAYLADAIAQRRQHPGTDMLSQVMTGEGNFTDIELLGMSHLLILAGLDTVTAAIGFSL 239 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 ELARRPQLR LRDNPKQ RVFIEEIVRLEPSAPVAPR+TTE V VGGMTLP G+ VRL Sbjct 240 FELARRPQLRKELRDNPKQTRVFIEEIVRLEPSAPVAPRITTEYVEVGGMTLPPGTSVRL 299 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 CMAAVNRD SD+MST+EL MDGKVHRHWGFGGGPHRCLGSHLAR+ELT++V EWL QIPD Sbjct 300 CMAAVNRDDSDSMSTNELNMDGKVHRHWGFGGGPHRCLGSHLARIELTVVVAEWLTQIPD 359 Query 366 FELAPDYAPEIRFPSKSF 383 FEL + P K F Sbjct 360 FELPDGLRAGDQLPLKEF 377 >gi|296170415|ref|ZP_06852003.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894886|gb|EFG74607.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=416 Score = 549 bits (1414), Expect = 3e-154, Method: Compositional matrix adjust. Identities = 268/398 (68%), Positives = 316/398 (80%), Gaps = 18/398 (4%) Query 3 TPGEDHAGS--------FYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRRE 54 P HAG+ F+LPRLE+STLP+A DRGVGWK LRDAGPVVFMNG YYLTRRE Sbjct 9 NPSHAHAGASGATGSAKFHLPRLEHSTLPLAADRGVGWKALRDAGPVVFMNGAYYLTRRE 68 Query 55 DVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSL 114 DVLAAL P +FS+ ALQPPG+P+PV+P AFDPPEHTRYR+ILQP+FSP ALSK+ P + Sbjct 69 DVLAALCQPNLFSAHLALQPPGSPVPVLPSAFDPPEHTRYRKILQPHFSPHALSKSRPVM 128 Query 115 RRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRP 174 RH V MI +AGRG CE MAD A L+P+Q+F+ LYGLPLEDRDR+I WKDA + Sbjct 129 ERHAVDMITDLAGRGACEVMADFARLYPYQVFMDLYGLPLEDRDRVIAWKDAAVDGGPE- 187 Query 175 HPTEADVAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGL 234 ELL Y T + +RR+NPG D+LS V G L+++E+LG+SHLL+L+GL Sbjct 188 ---------GNELLGYFTDAIVQRRQNPGSDMLSGVMTGPGDLTDLELLGMSHLLVLSGL 238 Query 235 DTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGG 294 DTV AA+GFSL ELARRPQLR LRD+P+QIRVFIEEIVRLEP+AP+A RVTT+ V VGG Sbjct 239 DTVAAAIGFSLFELARRPQLRRELRDDPEQIRVFIEEIVRLEPAAPLAARVTTDFVKVGG 298 Query 295 MTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTL 354 MTLP G+PVRLC AA+NRDGSD +STD+LVMDGKVHRHWGFGGGPHRC+GSHLAR+ELT+ Sbjct 299 MTLPPGTPVRLCTAAINRDGSDEISTDDLVMDGKVHRHWGFGGGPHRCIGSHLARIELTM 358 Query 355 LVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRW 392 +V EWL QIPDF+L Y PEI+FPSKSFALK+LPL W Sbjct 359 IVEEWLKQIPDFDLPQGYVPEIKFPSKSFALKSLPLSW 396 >gi|240170525|ref|ZP_04749184.1| cytochrome P450 143A4 Cyp143A4 [Mycobacterium kansasii ATCC 12478] Length=400 Score = 546 bits (1407), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 264/387 (69%), Positives = 313/387 (81%), Gaps = 10/387 (2%) Query 6 EDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKV 65 E+ +F+LPRLE+STLPMA DRGVGWKTLRDAGPVVFMNG YYLTRREDVLAAL PK+ Sbjct 23 ENRPLTFHLPRLEHSTLPMAADRGVGWKTLRDAGPVVFMNGAYYLTRREDVLAALCEPKL 82 Query 66 FSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAI 125 FS++ ALQPPG+P+PV+P AFDPPEHTRYR+ILQPYFSP L K+ P + RH MI A+ Sbjct 83 FSAQLALQPPGSPVPVLPSAFDPPEHTRYRKILQPYFSPHTLHKSRPMMERHAAEMIAAL 142 Query 126 AGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAAR 185 A R CE MAD A L+P+Q+F+ LYGLPLEDRD +IGWKDA +A H Sbjct 143 ACRNACEVMADFARLYPYQVFMDLYGLPLEDRDSVIGWKDAFVAGKSDGH---------- 192 Query 186 ELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 LL Y T + +RR+NP D+LSQV G LS++E+LG++ LLI++GLDTV AA+GF+L Sbjct 193 GLLAYFTEAIRQRRQNPSSDMLSQVMTGPGDLSDLELLGMTQLLIVSGLDTVAAAIGFAL 252 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 LELARRPQLR L +NP+QI+VF+EEIVRLEPSAP+A RVTT+ V VGGMTLP G+PVRL Sbjct 253 LELARRPQLRRELAENPEQIKVFVEEIVRLEPSAPLAARVTTDFVNVGGMTLPPGTPVRL 312 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 C AA+NRDGSD +STD+LVMDGK+HRHWGFGGGPHRCLGSHLAR+ELT++VGEWL QIPD Sbjct 313 CTAAINRDGSDVISTDDLVMDGKMHRHWGFGGGPHRCLGSHLARMELTIVVGEWLKQIPD 372 Query 366 FELAPDYAPEIRFPSKSFALKNLPLRW 392 FEL P Y I+FPSKSFALK+LPL W Sbjct 373 FELPPGYTAYIKFPSKSFALKSLPLSW 399 >gi|126436732|ref|YP_001072423.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236532|gb|ABN99932.1| cytochrome P450 [Mycobacterium sp. JLS] Length=385 Score = 525 bits (1353), Expect = 4e-147, Method: Compositional matrix adjust. Identities = 248/378 (66%), Positives = 310/378 (83%), Gaps = 0/378 (0%) Query 15 PRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQP 74 PRL Y++LPMA DR VGW TLRDAGPVVF++GW+YLTRR+DVLAALRNP++FSSRKA Sbjct 7 PRLAYASLPMAADRQVGWNTLRDAGPVVFVDGWFYLTRRDDVLAALRNPELFSSRKAFDV 66 Query 75 PGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAM 134 G+PLP+VP+AFDPPEHTR+R+ILQP+FSP LS+ALP+L++ + +++++A +GECEAM Sbjct 67 LGSPLPLVPIAFDPPEHTRFRKILQPFFSPHTLSEALPALQKQALDIVESVAAKGECEAM 126 Query 135 ADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAM 194 AD+A +P Q+FL L+GLPLEDR+RLI WKD+VIA++DRP AD+ A EL YLT Sbjct 127 ADIAIPYPSQVFLTLFGLPLEDRERLIAWKDSVIALADRPSLEGADLTPALELFAYLTEA 186 Query 195 VAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQL 254 + RR +PGPDVLSQV G+DPL + E +GLS+L +LAGLDTVT+A+G +LL LAR P L Sbjct 187 INARRADPGPDVLSQVLTGDDPLDDAEAIGLSYLFVLAGLDTVTSAMGSALLALARDPGL 246 Query 255 RAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDG 314 RAMLR +P Q+ VF+EEIVRLE AP+ PRVTT VT+G +TLP + VRLC+ A+NRD Sbjct 247 RAMLRADPGQLGVFVEEIVRLETPAPLVPRVTTAEVTIGDITLPPDTQVRLCLGAINRDD 306 Query 315 SDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAP 374 SDA+S + +VMDGKVHRHWGFGGGPHRCLGSHLAR+ELTL+VGEWL +IPDF LA Y P Sbjct 307 SDAISANHVVMDGKVHRHWGFGGGPHRCLGSHLARIELTLIVGEWLQRIPDFSLAAGYEP 366 Query 375 EIRFPSKSFALKNLPLRW 392 EI FP+ +FAL LPL+W Sbjct 367 EIVFPANTFALDRLPLQW 384 >gi|118466259|ref|YP_881740.1| cytochrome P450 143 [Mycobacterium avium 104] gi|254819954|ref|ZP_05224955.1| putative cytochrome P450 143 [Mycobacterium intracellulare ATCC 13950] gi|118167546|gb|ABK68443.1| putative cytochrome P450 143 [Mycobacterium avium 104] Length=385 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 230/377 (62%), Positives = 303/377 (81%), Gaps = 0/377 (0%) Query 15 PRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQP 74 P L +++LPMA DRGVGWK LRDAG VV ++G +YLT REDVLAALR+P++FSS+KA Sbjct 7 PELSFASLPMAADRGVGWKVLRDAGRVVSVDGIFYLTHREDVLAALRDPELFSSKKAFDV 66 Query 75 PGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAM 134 G+PLP+VP++FDPPEHTR+R+ILQP+FSP L + LPSL++ + +I+ +A +GECE + Sbjct 67 LGSPLPLVPISFDPPEHTRFRKILQPFFSPHTLKEMLPSLQQQAIEIIERVAAQGECEVV 126 Query 135 ADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAM 194 AD+A +P Q+FL L+GLPLEDRD+L+ WK +VIA+S+ P +AD+ A EL+ YLT Sbjct 127 ADVAIPYPSQVFLTLFGLPLEDRDKLVAWKTSVIAISEAPSLEDADLTPALELVAYLTEA 186 Query 195 VAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQL 254 + RR +PGPD+LSQ+ GE+PL + E++GLS L +LAGLDTVTAA+ +LLELAR P+L Sbjct 187 INARRADPGPDILSQLLNGEEPLDDAEIMGLSFLFVLAGLDTVTAAMSSALLELARNPEL 246 Query 255 RAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDG 314 RA L D+P QI VF+EEIVRLEP AP+ PRVTT VT+G +TLPA + VRLC+AA+NRD Sbjct 247 RATLHDDPDQIDVFVEEIVRLEPPAPMLPRVTTTEVTIGDVTLPADTMVRLCVAAINRDD 306 Query 315 SDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAP 374 SD +ST+++VMDGKVHRHWGFGGGPHRCLGSHLARLEL L+VGEWL +IP+F + P Sbjct 307 SDEISTNDVVMDGKVHRHWGFGGGPHRCLGSHLARLELKLIVGEWLRRIPEFSVKVGEEP 366 Query 375 EIRFPSKSFALKNLPLR 391 +I FP+ +F+L+ +PL+ Sbjct 367 QIVFPASTFSLERVPLK 383 >gi|145222354|ref|YP_001133032.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315442787|ref|YP_004075666.1| cytochrome P450 [Mycobacterium sp. Spyr1] gi|145214840|gb|ABP44244.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315261090|gb|ADT97831.1| cytochrome P450 [Mycobacterium sp. Spyr1] Length=390 Score = 472 bits (1215), Expect = 4e-131, Method: Compositional matrix adjust. Identities = 228/383 (60%), Positives = 292/383 (77%), Gaps = 0/383 (0%) Query 9 AGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSS 68 A LP++ Y LPM+ DRG GW TLRD GPV++ +GW+YLTRREDVLAALRNP+VFSS Sbjct 5 AAPLGLPQVLYGDLPMSRDRGHGWATLRDLGPVLYGDGWFYLTRREDVLAALRNPEVFSS 64 Query 69 RKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGR 128 R A +P+P+VPL FDPPEHTRYR IL P+FSP L+ LPSL+ +++ IA R Sbjct 65 RIAYDDMISPVPLVPLGFDPPEHTRYRHILHPFFSPQTLAALLPSLQAQVADIVEEIARR 124 Query 129 GECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELL 188 CE MA+LA +P Q+FL L+GLPL+DR+RLI WKDA+IA S P+ D+ A EL Sbjct 125 DRCEVMAELATPYPSQVFLTLFGLPLQDRERLIAWKDAIIAFSLTTDPSSVDLKPAVELY 184 Query 189 EYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLEL 248 YL+ VA +R +P VLS + G+DPL++ E +GLS + +LAGLDTVT+A+G ++LEL Sbjct 185 TYLSEAVAAQRDDPREGVLSHLLHGDDPLTDNEAVGLSLVFVLAGLDTVTSAIGATMLEL 244 Query 249 ARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMA 308 ARRP+LR LR++P+ I VF+EE++RLEP+AP+ RVTT PVTV G+TLPAGS VRLC+ Sbjct 245 ARRPELRGALREDPEGIAVFVEEMIRLEPAAPIVGRVTTRPVTVAGVTLPAGSEVRLCLG 304 Query 309 AVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFEL 368 A+NRDG+D S D+LV+DGK+H+HWGFGGGPHRCLGSHLAR+EL L+V EWL++IPDF+L Sbjct 305 AINRDGTDEHSGDDLVLDGKLHKHWGFGGGPHRCLGSHLARMELKLVVSEWLSRIPDFDL 364 Query 369 APDYAPEIRFPSKSFALKNLPLR 391 P Y PEI +PS + L LPLR Sbjct 365 EPGYVPEITWPSATCTLTGLPLR 387 >gi|126437368|ref|YP_001073059.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126237168|gb|ABO00569.1| cytochrome P450 [Mycobacterium sp. JLS] Length=394 Score = 470 bits (1209), Expect = 2e-130, Method: Compositional matrix adjust. Identities = 232/389 (60%), Positives = 288/389 (75%), Gaps = 3/389 (0%) Query 3 TPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRN 62 TP D G LP ++Y LPMA DRG GW LR GPV F +GW+YLT REDVLAALRN Sbjct 2 TPTHDGLG---LPHVQYGDLPMAQDRGAGWAALRGLGPVAFGDGWFYLTEREDVLAALRN 58 Query 63 PKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMI 122 P+VFSSR A +P+P+VPL FDPPEHTRYRRIL +FSP L + LPSL+ + +I Sbjct 59 PEVFSSRIAYDDMISPVPLVPLGFDPPEHTRYRRILHQFFSPQTLGELLPSLQAQAIEII 118 Query 123 DAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVA 182 +AIA ECE MADLA +P Q+FL L+GLPL DR+RLI WKDA+IA S P D+ Sbjct 119 EAIAVHDECEVMADLATPYPSQVFLTLFGLPLADRERLIAWKDAIIAFSLTTDPGSVDLT 178 Query 183 AARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVG 242 A EL YLT VAE+R P +LSQ+ G+DPL++ E GLS + +LAGLDTVTA++G Sbjct 179 PAVELYSYLTEAVAEQRNRPRDGILSQLLHGDDPLTDNEATGLSLVFVLAGLDTVTASIG 238 Query 243 FSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSP 302 +LLEL RRP+LR LRDN + F+EE++RLEP+APV RVTT PVTV G+ LPAG+ Sbjct 239 TALLELTRRPELRKALRDNLDNVPAFVEEMIRLEPAAPVVGRVTTRPVTVAGVDLPAGAE 298 Query 303 VRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQ 362 VRLC+ A+NRDGSDA+S D++V+DG++H+HWGFGGGPHRCLG+HLAR+EL L+V EWL + Sbjct 299 VRLCLGAINRDGSDALSGDDVVLDGRLHKHWGFGGGPHRCLGAHLARMELRLVVTEWLTR 358 Query 363 IPDFELAPDYAPEIRFPSKSFALKNLPLR 391 I DFELAP + PEI +PS + +L LPLR Sbjct 359 ISDFELAPGFVPEITWPSATCSLPRLPLR 387 >gi|108801385|ref|YP_641582.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119870538|ref|YP_940490.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108771804|gb|ABG10526.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119696627|gb|ABL93700.1| cytochrome P450 [Mycobacterium sp. KMS] Length=394 Score = 466 bits (1199), Expect = 3e-129, Method: Compositional matrix adjust. Identities = 230/389 (60%), Positives = 287/389 (74%), Gaps = 3/389 (0%) Query 3 TPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRN 62 TP D G LP ++Y LPMA DRG GW LR GPV + +GW+YLT REDVLAALRN Sbjct 2 TPTHDGLG---LPHVQYGDLPMAQDRGAGWAALRGLGPVAYGDGWFYLTEREDVLAALRN 58 Query 63 PKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMI 122 P+ FSSR A +P+P+VPL FDPPEHTRYRRIL +FSP L + LPSL+ + +I Sbjct 59 PEEFSSRIAYDDMISPVPLVPLGFDPPEHTRYRRILHQFFSPQTLGELLPSLQAQAIEII 118 Query 123 DAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVA 182 +AIA ECE MADLA +P Q+FL L+GLPL DR+RLI WKDA+IA S P D+ Sbjct 119 EAIAVHDECEVMADLATPYPSQVFLTLFGLPLADRERLIAWKDAIIAFSLTTDPGSVDLT 178 Query 183 AARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVG 242 A EL YLT VAE+R P +LSQ+ G+DPL++ E GLS + +LAGLDTVTA++G Sbjct 179 PAVELYSYLTEAVAEQRNRPRDGILSQLLHGDDPLTDNEATGLSLVFVLAGLDTVTASIG 238 Query 243 FSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSP 302 +LLEL RRP+LR LRDN + F+EE++RLEP+APV RVTT PVTV G+ LPAG+ Sbjct 239 TALLELTRRPELRKALRDNLDNVPAFVEEMIRLEPAAPVVGRVTTRPVTVAGVDLPAGAE 298 Query 303 VRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQ 362 VRLC+ A+NRDGSDA+S D++V+DG++H+HWGFGGGPHRCLG+HLAR+EL L+V EWL + Sbjct 299 VRLCLGAINRDGSDALSGDDVVLDGRLHKHWGFGGGPHRCLGAHLARMELRLVVTEWLTR 358 Query 363 IPDFELAPDYAPEIRFPSKSFALKNLPLR 391 I DFELAP + PEI +PS + +L LPLR Sbjct 359 ISDFELAPGFVPEITWPSATCSLPRLPLR 387 >gi|183982641|ref|YP_001850932.1| cytochrome P450 143A3 Cyp143A3 [Mycobacterium marinum M] gi|183175967|gb|ACC41077.1| cytochrome P450 143A3 Cyp143A3 [Mycobacterium marinum M] Length=390 Score = 462 bits (1190), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 229/380 (61%), Positives = 292/380 (77%), Gaps = 0/380 (0%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 +P Y+ LPMA DRG GW TLRDAGPVV +G+YYLTRR+DVL ALR+P+VFSS++A Sbjct 10 IPHFVYAELPMATDRGRGWATLRDAGPVVIGDGFYYLTRRDDVLDALRHPEVFSSKRAFD 69 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 G+PLP+VPLAFDPPEHTR+R++LQP+FSP AL+ LPSL+ + +IDAIA +CE Sbjct 70 ILGSPLPLVPLAFDPPEHTRFRKVLQPFFSPHALAAMLPSLQAQAIEIIDAIAAGSQCEV 129 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTA 193 + +LA +P Q+FL L+GL L DRDRLI WKDA+IA+ +AD+ A EL YL Sbjct 130 ITELAIPYPSQVFLTLFGLSLADRDRLIRWKDAIIALGLLASLDDADLTPALELTSYLVD 189 Query 194 MVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 +A RR+PG D+LSQV +G+DPL + E LGLS++ +LAGLDTVT+A+G +LLELARRPQ Sbjct 190 AIAAHRRHPGTDILSQVLLGDDPLDDSEALGLSYVFVLAGLDTVTSAIGAALLELARRPQ 249 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 LR +LR+N QI VF++EIVRLEP APV PRVTT V + G +PAGS V LC+ A+NRD Sbjct 250 LRQLLRENHGQIAVFVDEIVRLEPPAPVVPRVTTREVNIAGAKIPAGSRVWLCLGAINRD 309 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 GSDA S +++VMDGKVH+HWGFGGG HRCLGSHLAR+EL+L++ EWL +IP FELA Y Sbjct 310 GSDATSVNDVVMDGKVHKHWGFGGGTHRCLGSHLARMELSLVISEWLRRIPQFELACGYT 369 Query 374 PEIRFPSKSFALKNLPLRWS 393 PEI +PS + L L L+++ Sbjct 370 PEIDWPSATLGLSTLTLQFT 389 >gi|118618484|ref|YP_906816.1| cytochrome P450 143A3 Cyp143A3 [Mycobacterium ulcerans Agy99] gi|118570594|gb|ABL05345.1| cytochrome P450 143A3 Cyp143A3 [Mycobacterium ulcerans Agy99] Length=390 Score = 461 bits (1187), Expect = 8e-128, Method: Compositional matrix adjust. Identities = 229/380 (61%), Positives = 291/380 (77%), Gaps = 0/380 (0%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 +P Y+ LPMA DRG GW TLRDAGPVV +G+YYLTRR+DVL ALR+P+VFSS++A Sbjct 10 IPHFVYAELPMATDRGRGWATLRDAGPVVIGDGFYYLTRRDDVLDALRHPEVFSSKRAFD 69 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 G+PLP+VPLAFDPPEHTR+R++LQP+FSP AL+ LPSL+ + +IDAIA +CE Sbjct 70 ILGSPLPLVPLAFDPPEHTRFRKVLQPFFSPHALAAMLPSLQAQAIEIIDAIAAGSQCEV 129 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTA 193 + LA +P Q+FL L+GL L DRDRLI WKDA+IA+ +AD+ A EL YL Sbjct 130 ITKLAIPYPSQVFLTLFGLSLADRDRLIRWKDAIIALGLLASLDDADLTPALELTSYLVD 189 Query 194 MVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 +A RR+PG D+LSQV +G+DPL + E LGLS++ +LAGLDTVT+A+G +LLELARRPQ Sbjct 190 AIAAHRRHPGTDILSQVLLGDDPLDDSEALGLSYVFVLAGLDTVTSAIGAALLELARRPQ 249 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 LR +LR+N QI VF++EIVRLEP APV PRVTT V + G +PAGS V LC+ A+NRD Sbjct 250 LRQLLRENHGQIAVFVDEIVRLEPPAPVVPRVTTREVNIAGAKIPAGSRVWLCLGAINRD 309 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 GSDA S +++VMDGKVH+HW FGGG HRCLGSHLAR+EL+L++ EWL +IP FELA Y Sbjct 310 GSDATSVNDVVMDGKVHKHWDFGGGTHRCLGSHLARMELSLVISEWLCRIPQFELACGYT 369 Query 374 PEIRFPSKSFALKNLPLRWS 393 PEI +PS + L LPL+++ Sbjct 370 PEIDWPSATLGLSTLPLQFT 389 >gi|120405932|ref|YP_955761.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119958750|gb|ABM15755.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=387 Score = 459 bits (1182), Expect = 3e-127, Method: Compositional matrix adjust. Identities = 224/377 (60%), Positives = 281/377 (75%), Gaps = 0/377 (0%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 LP + Y LPMA DRG GW TLR+ GPV + +GWYYLTRR+DVLAALRNP+VFSSR A Sbjct 4 LPHVLYGDLPMAADRGAGWATLREFGPVAYGDGWYYLTRRDDVLAALRNPEVFSSRIAYD 63 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 +P+P+VPL FDPPEHTRYRRIL P+FSP AL LPSL+ +++ IA R CE Sbjct 64 DMISPVPLVPLGFDPPEHTRYRRILHPFFSPQALGVLLPSLQAQAADIVETIAQRDACEV 123 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTA 193 MA+LA +P Q+FL L+GLPL+DR+RLI WKDA+IA S PT D+ A EL YLT Sbjct 124 MAELATPYPSQVFLTLFGLPLQDRERLIAWKDAIIAFSLTNDPTSVDLTPAVELYGYLTE 183 Query 194 MVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 VA +R P +LS + G++ L++ E +GLS + +LAGLDTVT+ +G ++LELARRP+ Sbjct 184 AVARQREKPREGILSHLLHGDEQLTDNEAVGLSLVFVLAGLDTVTSTIGATMLELARRPE 243 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 LRA L +P I F+EE++RLEP+APV RVTT VTV G+TLP G+ VRLC+ A+NRD Sbjct 244 LRAALLGDPDGIAGFVEEMIRLEPAAPVVGRVTTREVTVAGVTLPKGAEVRLCLGAINRD 303 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 G+D S D+ V+DGK+H+HWGFGGGPHRCLGSHLAR+EL L+V EWL++IPDFELAP Y Sbjct 304 GADEHSGDDFVLDGKLHKHWGFGGGPHRCLGSHLARMELRLVVTEWLSRIPDFELAPGYV 363 Query 374 PEIRFPSKSFALKNLPL 390 PEI +PS + L LPL Sbjct 364 PEITWPSATCTLPTLPL 380 >gi|333992054|ref|YP_004524668.1| cytochrome P450 [Mycobacterium sp. JDM601] gi|333488021|gb|AEF37413.1| cytochrome P450 143A3 Cyp143A3 [Mycobacterium sp. JDM601] Length=392 Score = 452 bits (1163), Expect = 4e-125, Method: Compositional matrix adjust. Identities = 222/378 (59%), Positives = 276/378 (74%), Gaps = 0/378 (0%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 LP Y+ LPMA DRG GW LRD GPV + G YYLTRREDVLAALRN +VFSSR Sbjct 10 LPHFAYADLPMARDRGKGWAALRDLGPVAYGEGAYYLTRREDVLAALRNWEVFSSRIPYD 69 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 +P+P+VPL FDPP+HTRYR++L YFSP L LPSL+ +I IA CE Sbjct 70 DMISPVPLVPLGFDPPDHTRYRQLLHRYFSPQTLMALLPSLQSQAAEIISGIAAHDRCEV 129 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTA 193 MA+LA +P Q+FL L+GLPLEDRDRL+ WKDA+IA+S P D+ EL +YLT Sbjct 130 MAELATPYPSQVFLTLFGLPLEDRDRLVAWKDAIIALSLTDDPASVDLTPTVELFDYLTE 189 Query 194 MVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 VA +R++P P +LS++ G DPL + E +GLS + +LAGLDTVTA +G ++LELAR P Sbjct 190 AVARQRKDPLPGILSELLRGADPLDDNEAIGLSLVFVLAGLDTVTATIGATMLELARGPA 249 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 LRA LR++P + VF+EE++RLEP+APV R TT PVT+ G+ +PAG+ VRLC+ A+NRD Sbjct 250 LRAALREDPDGVAVFVEEMIRLEPAAPVVGRATTRPVTIAGVEIPAGAEVRLCLGAINRD 309 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 GSD S DE V+DGKVH+HWGFGGGPHRCLGSHLARLEL L+V EWL +IPDF LAP + Sbjct 310 GSDEYSGDEPVLDGKVHKHWGFGGGPHRCLGSHLARLELKLVVSEWLARIPDFGLAPGFV 369 Query 374 PEIRFPSKSFALKNLPLR 391 PEI +PS + +L LPLR Sbjct 370 PEISWPSATCSLPALPLR 387 >gi|289761935|ref|ZP_06521313.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis GM 1503] gi|289709441|gb|EFD73457.1| cytochrome P450 143 cyp143 [Mycobacterium tuberculosis GM 1503] Length=228 Score = 347 bits (889), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 170/171 (99%), Positives = 170/171 (99%), Gaps = 0/171 (0%) Query 223 LGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVA 282 GLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVA Sbjct 58 FGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVA 117 Query 283 PRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRC 342 PRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRC Sbjct 118 PRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRC 177 Query 343 LGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 393 LGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS Sbjct 178 LGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS 228 >gi|111222778|ref|YP_713572.1| putative cytochrome P450 [Frankia alni ACN14a] gi|111150310|emb|CAJ62007.1| Putative cytochrome P450 [Frankia alni ACN14a] Length=395 Score = 329 bits (844), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 180/383 (47%), Positives = 243/383 (64%), Gaps = 13/383 (3%) Query 17 LEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPG 76 L + LP+ DR W+ +R+ G +V + LT V AA RNP VFSSR+A G Sbjct 9 LTFEDLPVRDDRDAAWRLIRERGGIVQLEPDVALTDHTLVEAAFRNPAVFSSRQAFDSLG 68 Query 77 NPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMAD 136 +PLP+VP+AFDPPEH RYR ILQP+FSP ++ P LRR +I + RG C+ +AD Sbjct 69 SPLPLVPIAFDPPEHARYRHILQPFFSPRSIRPLEPELRRQLAELIAPLPARGACDFVAD 128 Query 137 LANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRP---HPTEADVAAARELLEYLTA 193 +A++FP Q FL +GLPL+ RD+ + WKDA++A+SD EAD+ A EL YL+ Sbjct 129 VASVFPVQAFLTFFGLPLDMRDQFVAWKDAILALSDPSGAISTDEADLRHAGELFTYLSE 188 Query 194 MVAERRRNPGPDVLSQVQI--GEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARR 251 +VA RR PGPDVLS++ G+D L++ EV+GL L +LAGLDTVT A+GF + LAR Sbjct 189 LVAARRGVPGPDVLSELLCLDGDDALTDAEVIGLCFLFVLAGLDTVTDALGFGMERLARN 248 Query 252 PQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVN 311 P R + D+P + +EE++RL+P AP PR+TT +GG TLPAG+ V +AA N Sbjct 249 PDRRQEIVDDPGLVPAAVEELLRLDPPAPFVPRITTAQTELGGRTLPAGTRVTAYIAACN 308 Query 312 RDGSDAMSTDELVMDGKVHR----HWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFE 367 RD +A D +D HR H FG G HRCLGSHLARLE+ L+ EW IP ++ Sbjct 309 RD--EARYPDPYGVD--FHRGDNPHASFGVGVHRCLGSHLARLEMRLVYEEWHRLIPHYD 364 Query 368 LAPDYAPEIRFPSKSFALKNLPL 390 +AP +AP ++FP + L+ LPL Sbjct 365 IAPGFAPTVKFPRGTVGLEALPL 387 >gi|126436602|ref|YP_001072293.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236402|gb|ABN99802.1| cytochrome P450 [Mycobacterium sp. JLS] Length=392 Score = 315 bits (806), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 169/379 (45%), Positives = 236/379 (63%), Gaps = 6/379 (1%) Query 17 LEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPG 76 L + LP DR W+ LR+AG V LT E V A + P++FSS KA G Sbjct 10 LNINDLPFTEDRSRAWRELREAGEAVLSGEEIVLTSAEAVEFAAKRPQIFSSAKAFDVLG 69 Query 77 NPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMAD 136 +P+P+VP+A DPP+HTR+RR+L P+FSP +++ P LRR +IDAI +GECE +AD Sbjct 70 SPVPLVPIAIDPPDHTRFRRMLDPFFSPKRMAEREPELRRQAGELIDAIVAKGECEVVAD 129 Query 137 LANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSD--RPHPTEADVAAARELLEYLTAM 194 LA FP Q+FL L+GLP+ DRDRL+ WKDA++ +D PT + A EL YL Sbjct 130 LATPFPSQVFLTLFGLPMADRDRLVHWKDAILQFTDPGSGEPTPEVLTYALELFTYLNEH 189 Query 195 VAERRRN-PGPDVLSQV--QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARR 251 +AERR + G D+L+Q+ E + + E+LGL + +LAGLDTVT+AVGFSL +LA Sbjct 190 IAERRTDTSGSDMLTQLIHDTDEGGMDDNEILGLCFMFVLAGLDTVTSAVGFSLAKLAED 249 Query 252 PQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVN 311 LR + ++ I FIEE++R++ P APRVTTE V V G +P + V L + + Sbjct 250 ADLRRRISNDYSLIPAFIEELLRVDGPVPFAPRVTTEEVEVAGRVVPKDTRVMLSYGSAD 309 Query 312 RDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPD 371 RD DE+ +D K H+ FG GPHRCLGSHLARLEL L++ EW +IP++ L Sbjct 310 RDPRRYDDVDEVHVDSKA-VHFAFGRGPHRCLGSHLARLELRLILEEWHARIPEYTLVDG 368 Query 372 YAPEIRFPSKSFALKNLPL 390 P++ +P+ + L+++PL Sbjct 369 NPPQVPWPTGTMGLQSVPL 387 >gi|254820065|ref|ZP_05225066.1| cytochrome P450 [Mycobacterium intracellulare ATCC 13950] Length=396 Score = 314 bits (805), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 172/380 (46%), Positives = 241/380 (64%), Gaps = 8/380 (2%) Query 17 LEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPG 76 L + LP A DR W+ LR+AG V LT E V A + P++FSS +A G Sbjct 10 LNINDLPFAEDRTRAWRELREAGEAVSSGEEVVLTSAEAVEFAAKKPEIFSSARAFDRLG 69 Query 77 NPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMAD 136 +P+P+VP+A DPP+HTR+RR+L P+F P +++ P LRR +IDAI GEC+ + D Sbjct 70 SPVPLVPIAIDPPDHTRFRRMLDPFFGPKKMAEREPELRRQAGELIDAIVASGECDVVPD 129 Query 137 LANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD---VAAARELLEYLTA 193 LA FP Q+FL L+GLP+ DRDRL+ WKDA++ +D P TEA +A A EL YLT Sbjct 130 LATPFPSQVFLTLFGLPMADRDRLVKWKDAILQFTD-PSSTEATPEVMAHALELFSYLTE 188 Query 194 MVAERRRN-PGPDVLSQV--QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELAR 250 +AERR + G D+L+Q+ E +S+ E+LGL + +LAGLDTVT+AVGFSL LA Sbjct 189 HIAERRADATGNDMLTQLIQDTDEGGMSDNEILGLCFMFVLAGLDTVTSAVGFSLARLAA 248 Query 251 RPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAV 310 +R + + I FIEEI+R++ P APRVTTE V V G +P + V L + Sbjct 249 DDDMRRRIAHDFTLIPAFIEEILRVDGPVPFAPRVTTEGVEVAGRFVPKDTTVMLSYGSA 308 Query 311 NRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAP 370 +RD D++ +D KV H+ FG GPHRCLGSHLARLEL L++ EW ++IP++ LA Sbjct 309 DRDPRRYQDADQIHLDSKV-VHFAFGRGPHRCLGSHLARLELRLILEEWHSRIPEYTLAL 367 Query 371 DYAPEIRFPSKSFALKNLPL 390 P++ +P+ + +L+++PL Sbjct 368 GKPPQMPWPTGTMSLQSVPL 387 >gi|118463806|ref|YP_881849.1| cytochrome P450 [Mycobacterium avium 104] gi|118165093|gb|ABK65990.1| cytochrome P450 [Mycobacterium avium 104] Length=396 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 172/380 (46%), Positives = 241/380 (64%), Gaps = 8/380 (2%) Query 17 LEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPG 76 L + LP A DR W+ LR+AG V LT E V A + P++FSS +A G Sbjct 10 LNINDLPFAEDRTRAWRELREAGEAVSSGEEVVLTSAEAVEFAAKKPEIFSSARAFDRLG 69 Query 77 NPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMAD 136 +P+P+VP+A DPP+HTR+RR+L P+F P +++ P LRR +IDAI GEC+ + D Sbjct 70 SPVPLVPIAIDPPDHTRFRRMLDPFFGPKKMAEREPELRRQAGELIDAIVASGECDVVPD 129 Query 137 LANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD---VAAARELLEYLTA 193 LA FP Q+FL L+GLP+ DRDRL+ WKDA++ +D P TEA +A A EL YLT Sbjct 130 LATPFPSQVFLTLFGLPMADRDRLVKWKDAILQFTD-PSSTEATPEVMAHALELFSYLTE 188 Query 194 MVAERRRN-PGPDVLSQV--QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELAR 250 +AERR + G D+L+Q+ E +S+ E+LGL + +LAGLDTVT+AVGFSL LA Sbjct 189 HIAERRADATGNDMLTQLIQDTDEGGMSDNEILGLCFMFVLAGLDTVTSAVGFSLARLAA 248 Query 251 RPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAV 310 +R + + I FIEEI+R++ P APRVTTE V V G +P + V L + Sbjct 249 DDDMRRRVAHDFTLIPAFIEEILRVDGPVPFAPRVTTEGVEVAGRFVPKDTTVMLSYGSA 308 Query 311 NRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAP 370 +RD D++ +D KV H+ FG GPHRCLGSHLARLEL L++ EW ++IP++ LA Sbjct 309 DRDPRRYQDADQIHLDSKV-VHFAFGRGPHRCLGSHLARLELRLILEEWHSRIPEYTLAL 367 Query 371 DYAPEIRFPSKSFALKNLPL 390 P++ +P+ + +L+++PL Sbjct 368 GKPPQMPWPTGTMSLQSVPL 387 >gi|118465871|ref|YP_881169.1| cytochrome P450 126 [Mycobacterium avium 104] gi|118167158|gb|ABK68055.1| putative cytochrome P450 126 [Mycobacterium avium 104] Length=397 Score = 311 bits (798), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 172/385 (45%), Positives = 236/385 (62%), Gaps = 9/385 (2%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 LP++ LPM R W L D P+V + Y +TRR+ V L+NP +FSS++A Sbjct 6 LPKVCTDDLPMPEARDDAWHQL-DKHPLVEVEDGYAVTRRDVVELVLKNPSLFSSKRAFD 64 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 +P+P+VP+AFDPPE TRYRRILQP+FSP + P LRR V +I+ IA RG+C+ Sbjct 65 VLASPVPLVPIAFDPPEQTRYRRILQPFFSPRMIKPLEPDLRRQVVDLIEPIARRGQCDF 124 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAA------AREL 187 +A++A +FP Q+FL L+GLPL+ RD+ I WKDAV+ +S T D AA A EL Sbjct 125 IAEVAAVFPIQVFLTLFGLPLDMRDQFIEWKDAVLNLSAAAGQTSVDEAAQEGMQKALEL 184 Query 188 LEYLTAMVAERRRNPGPDVLSQVQIGE--DPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 YLT ++ +RR PG DVLSQV E D LS+ E +GL L +LAGLDTV A+GF + Sbjct 185 FMYLTDLIQKRRGAPGDDVLSQVLSIEPPDALSDEEAVGLCFLFVLAGLDTVMDALGFGM 244 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 LA P R + ++P I +EE++RL+P AP PRV+T+ VTV G TLP G+ + Sbjct 245 QRLAENPDKRQEIVNDPSLIPAAMEELLRLDPPAPFVPRVSTQEVTVAGHTLPEGTRITN 304 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 +A NRD + ++ +RH FG G HRCLGSHLARLE+ +L EW +IP+ Sbjct 305 YLAVANRDERQFPNPYDIDFHRTENRHVSFGMGVHRCLGSHLARLEMAVLYEEWHKRIPN 364 Query 366 FELAPDYAPEIRFPSKSFALKNLPL 390 + + P P + +P + L +L L Sbjct 365 YHITPGTTPRVHWPRGTVGLDSLHL 389 >gi|111224855|ref|YP_715649.1| cytochrome P450 [Frankia alni ACN14a] gi|111152387|emb|CAJ64123.1| Cytochrome P450 [Frankia alni ACN14a] Length=440 Score = 308 bits (789), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 175/388 (46%), Positives = 234/388 (61%), Gaps = 17/388 (4%) Query 16 RLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPP 75 ++ S LP+A DR W+ LR+ G V ++G T E V LR P +FSS+KA Sbjct 41 KVTLSNLPIARDRDAAWRQLREHGRTVLLDGGLAATDVETVETVLRQPAIFSSKKAFDVL 100 Query 76 GNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMA 135 G+PLP+VP+AFDPP+ TRYRRILQP+FSP A+ LRR V +++ + RG CE ++ Sbjct 101 GSPLPLVPIAFDPPDQTRYRRILQPFFSPRAIRPLEDELRRQIVEIVEPLVRRGSCEYVS 160 Query 136 DLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARE-------LL 188 ++A +FP Q+FL L+GLPLE RD+ I WKDA++ +SD T D AA L Sbjct 161 EVAGIFPVQVFLTLFGLPLEMRDQFIEWKDAILGLSDPSGNTALDEAATEAAMATALGLF 220 Query 189 EYLTAMVAERRRNPGPDVLSQVQI--GEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLL 246 YL +V RR G DVLSQ+ G++ L++ E +GL L +LAGLDTV A+ F Sbjct 221 SYLADLVPARRGVAGDDVLSQLLCLEGDEALTDEEAVGLCFLFVLAGLDTVVDALSFGTD 280 Query 247 ELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLC 306 L R P R + D+P I IEE++RL+P AP PRVTTE + G TLPAG+ V Sbjct 281 RLIRNPDRRREIVDDPALIPAAIEELLRLDPPAPFVPRVTTEQTVLDGRTLPAGTRVTTN 340 Query 307 MAAVNRDGSDAMSTDELVMDGKVHR----HWGFGGGPHRCLGSHLARLELTLLVGEWLNQ 362 +AA NRD A D ++ HR H FG G HRCLGSHLARLE+ L+ EW Sbjct 341 LAAANRD--PARHPDPYTVN--FHRGESPHLSFGAGVHRCLGSHLARLEMRLVFEEWHRL 396 Query 363 IPDFELAPDYAPEIRFPSKSFALKNLPL 390 IPD++LAP +P++++P + L LPL Sbjct 397 IPDYDLAPGASPQVKWPRGTLGLDALPL 424 >gi|118466761|ref|YP_881172.1| cytochrome P450 [Mycobacterium avium 104] gi|118168048|gb|ABK68945.1| cytochrome P450 [Mycobacterium avium 104] Length=386 Score = 308 bits (789), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 165/379 (44%), Positives = 239/379 (64%), Gaps = 8/379 (2%) Query 20 STLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPL 79 + LP A DR W+ LR+AG V LT E V A + P +FSS KA G+P+ Sbjct 8 NDLPFAEDRSRAWRELREAGEAVLSGEEIVLTSAEAVEFAAKRPDIFSSAKAFDRLGSPV 67 Query 80 PVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLAN 139 P++P+A DPP+HTR+RR+L P+FSP +++ P LR+ +IDAI +G + +ADLA Sbjct 68 PLIPIAIDPPDHTRFRRMLDPFFSPKKMAEREPELRKQAGELIDAILAKGHSDVVADLAT 127 Query 140 LFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEAD---VAAARELLEYLTAMVA 196 FP Q+FL L+GLP+ DRDRL+ WKD+++ +D P TEA +A A EL YLT +A Sbjct 128 PFPSQVFLTLFGLPMADRDRLVQWKDSILEFTD-PSSTEATPEVLAHAMELFTYLTEHIA 186 Query 197 ERRRN-PGPDVLSQVQIG--EDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 RR + G D+L+Q+ E + + E+LGL + +LAGLDTVT+AVGF+L +LA P+ Sbjct 187 ARRADTTGSDMLTQLMQNSEEGGMDDNEILGLCFMFVLAGLDTVTSAVGFALAKLAGDPE 246 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 LR + ++ I FIEE++R++ P APRVTT+ V V G +P + V L + +RD Sbjct 247 LRRRISNDYSLIPAFIEELLRVDGPVPFAPRVTTQEVEVAGRVVPKDTTVMLSYGSADRD 306 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 D + +D K H+ FG GPHRCLGSHLARLEL +++ EW +IP++ LA Sbjct 307 PLRYEDADNVHLDSKA-VHFAFGRGPHRCLGSHLARLELRIILEEWHKRIPEYSLADGKD 365 Query 374 PEIRFPSKSFALKNLPLRW 392 P++ +P+ + LK++PL + Sbjct 366 PQMPWPTGTMGLKSVPLTF 384 >gi|126436607|ref|YP_001072298.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236407|gb|ABN99807.1| cytochrome P450 [Mycobacterium sp. JLS] Length=418 Score = 301 bits (771), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 170/385 (45%), Positives = 229/385 (60%), Gaps = 9/385 (2%) Query 14 LPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQ 73 LP++ LPM V R W+ L D P+V + Y T R+ V L+NP VFSS++A Sbjct 29 LPKVSTEALPMPVARDEAWRAL-DEHPLVEVEDGYAATSRDFVELVLKNPSVFSSKRAFD 87 Query 74 PPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEA 133 +P+P+VP+AFDPPE RYRRILQP+FSP + LR V +I+ I RGEC+ Sbjct 88 VLASPVPLVPIAFDPPEQARYRRILQPFFSPRVIKPLEADLRAQMVELIEPIVARGECDF 147 Query 134 MADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAA------AREL 187 +A++A++FP Q+FL L+GLPLE RD+ I WK+AV+ +S T D AA A EL Sbjct 148 VAEVASVFPTQVFLTLFGLPLEMRDQFIEWKNAVLNLSAAAGQTTVDEAAQEGMLKAAEL 207 Query 188 LEYLTAMVAERRRNPGPDVLSQVQIGE--DPLSEIEVLGLSHLLILAGLDTVTAAVGFSL 245 YLT ++ +RR PG DVLSQV E D LS+ E +GL L ILAGLDTV ++GF + Sbjct 208 FMYLTELIQQRRGVPGDDVLSQVLNIEPPDALSDEEAIGLCFLFILAGLDTVMDSLGFGM 267 Query 246 LELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRL 305 LA P R + ++P I V +EE++RL+P AP PRVTT+ VG TLP GS + Sbjct 268 QRLAENPDRRREIVEDPALIPVAMEELLRLDPPAPFIPRVTTQDTQVGAHTLPEGSRITS 327 Query 306 CMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPD 365 +A NRD + E+ +RH FG G HRCLGSHLARLE+ + EW +IP Sbjct 328 YLAVANRDEKLFPNPYEIDFHRSDNRHITFGTGVHRCLGSHLARLEMQVAYEEWHKRIPH 387 Query 366 FELAPDYAPEIRFPSKSFALKNLPL 390 + + P + +P + L +L L Sbjct 388 YHITEGTTPHVHWPRGTVGLDSLHL 412 >gi|302546892|ref|ZP_07299234.1| P450 heme-thiolate protein [Streptomyces hygroscopicus ATCC 53653] gi|302464510|gb|EFL27603.1| P450 heme-thiolate protein [Streptomyces himastatinicus ATCC 53653] Length=411 Score = 244 bits (623), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 149/384 (39%), Positives = 204/384 (54%), Gaps = 14/384 (3%) Query 22 LPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPV 81 LP+A R W+TL G LT V A L+ P FS K + P+ Sbjct 21 LPVAERRDDAWRTLAALGEPAPTADGLALTSFAVVKAVLKAPDRFSLAKVFEAVETGYPL 80 Query 82 VPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLF 141 +PLAFDPPE T YRRILQP FSP + +LR V +I+A+ RG C+ +AD+A F Sbjct 81 IPLAFDPPEQTHYRRILQPLFSPRRIRPLTDALRAQAVDLIEAVKARGGCDFVADIAVPF 140 Query 142 PFQLFLVLYGLPLEDRDRLIGWKDAV----------IAMSDRPHPTEADVAAARELLEYL 191 P Q L L +PL DRDRLI WKDA + ++D D A + YL Sbjct 141 PAQALLTLLDMPLADRDRLIAWKDAALQLTADAAGELVLTDEERAARVDQTMA--MAGYL 198 Query 192 TAMVAERRRNPGPDVLSQVQI--GEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELA 249 ++ RR +PG D+LS++ GED S+ E GL +L+LAGL+TVT A+G ++ LA Sbjct 199 AELIQARRTHPGDDMLSEILALDGEDRFSDEEATGLCLMLVLAGLETVTDALGLAMERLA 258 Query 250 RRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAA 309 P R L D+P + +EE++RL+P AP PR+TTE V +GG +PAG+ V + Sbjct 259 TDPARRRELADDPSLVPAAVEELLRLDPPAPFLPRITTEDVEIGGCPIPAGTLVNAHLTT 318 Query 310 VNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELA 369 NRD S + + H FG G HRCLG+HLARLE+ L++ EW I D+ +A Sbjct 319 ANRDESCWPHPHDTDFHRPENPHTSFGVGVHRCLGTHLARLEMQLILEEWHRHISDYAIA 378 Query 370 PDYAPEIRFPSKSFALKNLPLRWS 393 R + L++L L + Sbjct 379 EGTPHRARLIRANIGLESLHLTFD 402 >gi|296170209|ref|ZP_06851802.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895085|gb|EFG74803.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=383 Score = 236 bits (603), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 157/404 (39%), Positives = 215/404 (54%), Gaps = 45/404 (11%) Query 4 PGEDH---AGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVF------MNGWYYLTRRE 54 PG DH G LP DR W LR GPVVF MNG Y LTR + Sbjct 9 PGIDHPSPIGGKLLPDF------FTADRSELWDALRKRGPVVFIEDSAFMNG-YCLTRAD 61 Query 55 DVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSL 114 DVLAALRNP+VFS A D P+H R+R ILQP S A+ + P+L Sbjct 62 DVLAALRNPEVFSHN---------------AVDRPDHARWRAILQPLLSATAVKQMQPAL 106 Query 115 RRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRP 174 + A+++A+A +G CE +AD+A F Q+ L + GLP +D RL+ W+ A+ A+ P Sbjct 107 QDQAAAVVEAVAAQGSCEVIADVAEPFAAQVLLTVLGLPPQDGHRLLRWEKALWAIQRAP 166 Query 175 HPTE-----ADVAAARELLEYLTAMVAERRRNPG-PDVLSQVQIGEDPLSEIEVLGLSHL 228 AD+ E+L YL A+RR +P V+S + G++ + + + + Sbjct 167 LTAGTGVPFADLVQKVEMLAYLAEAFAQRRASPDIAGVMSGLVAGDEGFDDADACAVVEM 226 Query 229 LILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTE 288 LI AG+ +AVGF L+LAR P+L A LR+NP I F+E+++R EP APV R + Sbjct 227 LIAAGITPFRSAVGFVFLDLARDPRLCASLRENPAGIEGFVEDVLRREPPAPVIIRRAAQ 286 Query 289 PVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLA 348 VTV G+ +PAG+ V LC+ A A+ D G +W FGGGPHRC+ LA Sbjct 287 NVTVAGVEIPAGAWVGLCVGA-------AIQEDLAAGHGSRADYWAFGGGPHRCVAVSLA 339 Query 349 RLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRW 392 + LT+LV EWL IP F L + P + ++ L +LPLRW Sbjct 340 KTALTVLVSEWLRTIPAFGLDAESVPPVIL-EEAVRLSSLPLRW 382 >gi|118465105|ref|YP_881420.1| cytochrome P450 superfamily protein [Mycobacterium avium 104] gi|118166392|gb|ABK67289.1| cytochrome P450 superfamily protein [Mycobacterium avium 104] Length=389 Score = 231 bits (589), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 140/367 (39%), Positives = 204/367 (56%), Gaps = 12/367 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR++ PV L+R D+ AL++ ++FSS GN P++PL DPPEH Sbjct 22 YKALRESNPVFRSPQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRRIL P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRILDPLFTPREMARREPLVTELVNEMIDRFAARGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPLED DR + WKD VI + DR H + A VA +++ EY + E P DV Sbjct 142 LPLEDLDRFLLWKDGVIRPAGDSGFDRRHESSAGVA--QQIYEYFDKAIDEHIAVPRDDV 199 Query 207 LSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPK 263 LS + +G PLS E+L + L ++AGLDTVT ++ + LAR PQ R L + P Sbjct 200 LSAMIAADVGGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPQHRRQLVERPD 259 Query 264 QIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDEL 323 + +EE++R E P RV T+ V VGG + G V + A N D ++ + + Sbjct 260 VLPGAVEELLRWETPVPGVARVATQDVEVGGCPISKGERVSPLLGAANTDPAEFPDPETV 319 Query 324 VMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSF 383 +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 320 DFTRSPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYEIKP--GTQLTYTAALR 377 Query 384 ALKNLPL 390 ++++LPL Sbjct 378 SVESLPL 384 >gi|158316356|ref|YP_001508864.1| cytochrome P450 [Frankia sp. EAN1pec] gi|158111761|gb|ABW13958.1| cytochrome P450 [Frankia sp. EAN1pec] Length=399 Score = 231 bits (588), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 137/350 (40%), Positives = 197/350 (57%), Gaps = 12/350 (3%) Query 32 WKTLRDAGPVV---FMNGWYYLTRREDVLAALRNPKVFSSRK-ALQPPGNPLPVVPLAFD 87 + LRD PVV F NG+Y LTR ED+L+A ++ FS++ + P +P Sbjct 31 FDQLRDEAPVVRNTFANGYYVLTRYEDILSAYQDTDTFSTQAVTVLEPDPSYRWIPHMLG 90 Query 88 PPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFL 147 EH ++RR L PYFSP A+ +R V +I++ A RG C+ + D + FP +FL Sbjct 91 GNEHRQWRRQLGPYFSPRAIEGLDDRIRARAVGLIESFADRGSCDVITDFSFHFPTTIFL 150 Query 148 VLYGLPLEDRDRLIGWKDAVIAMSDRPHPTE---ADVAAARELLEYLTAMVAERRRNPGP 204 L GLP+ D DR + W +A I S+ P E A + EY +++A+RRR PG Sbjct 151 ELMGLPVGDLDRFMAW-EANILHSNGSTPEEIAHNRTTAMAAVYEYFGSVIADRRRRPGD 209 Query 205 DVLSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDN 261 D++S ++ P+++ EVL + +AGLDTV AA+G+SL LA P+ RA + + Sbjct 210 DLVSHAIAFKVDGRPVTDDEVLSYCFFMFMAGLDTVAAALGYSLYHLATHPEDRARIVAD 269 Query 262 PKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTD 321 P I IEEI+R + + R T + V G + AGS V+L + A RDG+ S Sbjct 270 PALIPSAIEEILRAY-AFTIPARKVTRDIEVAGCPIAAGSMVQLPIKAAMRDGAAFASAS 328 Query 322 ELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPD 371 E+++D K + H FG GPHRCLGSHLAR EL + + EW +IPD+ LA D Sbjct 329 EVLIDRKPNNHIAFGAGPHRCLGSHLARHELAIALEEWHKRIPDYRLADD 378 >gi|254774922|ref|ZP_05216438.1| cytochrome P450 superfamily protein [Mycobacterium avium subsp. avium ATCC 25291] Length=389 Score = 230 bits (586), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 139/367 (38%), Positives = 204/367 (56%), Gaps = 12/367 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR++ PV L+R D+ AL++ ++FSS GN P++PL DPPEH Sbjct 22 YKALRESNPVFRSPQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRRIL P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRILDPLFTPREMARREPLVTELVNEMIDRFAARGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPLED DR + WKD VI + DR H + A VA +++ EY + E P DV Sbjct 142 LPLEDLDRFLLWKDGVIRPAGDSGFDRRHESSAGVA--QQIYEYFDKAIDEHIAVPRDDV 199 Query 207 LSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPK 263 LS + +G PLS E+L + L ++AGLDTVT ++ + LAR P+ R L + P Sbjct 200 LSAMIAADVGGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPEHRRQLVERPD 259 Query 264 QIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDEL 323 + +EE++R E P RV T+ V VGG + G V + A N D ++ + + Sbjct 260 VLPGAVEELLRWETPVPGVARVATQDVEVGGCPISKGERVSPLLGAANTDPAEFPDPETV 319 Query 324 VMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSF 383 +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 320 DFTRSPNRHRAFGGGPHRCLGSHLARMELRVALREFHGRIPDYEIKP--GTQLTYTAALR 377 Query 384 ALKNLPL 390 ++++LPL Sbjct 378 SVESLPL 384 >gi|336461837|gb|EGO40693.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=389 Score = 229 bits (585), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 140/367 (39%), Positives = 204/367 (56%), Gaps = 12/367 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR++ PV L+R D+ AL++ ++FSS GN P++PL DPPEH Sbjct 22 YKALRESNPVFRSTQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRRIL P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRILDPLFTPREMARREPLVTELVNEMIDRFAPRGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPLED DR + WKD VI + DR H + A VA +++ EY + E P DV Sbjct 142 LPLEDLDRFLLWKDGVIRPAGDSGFDRRHESSAGVA--QQIYEYFDKAIDEHIAVPRDDV 199 Query 207 LSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPK 263 LS + +G PLS E+L + L ++AGLDTVT ++ + LAR PQ R L + P Sbjct 200 LSAMIAADVGGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPQHRRQLVERPD 259 Query 264 QIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDEL 323 + +EE++R E P RV T+ V VGG + G V + A N D ++ + + Sbjct 260 VLPGAVEELLRWETPVPGVARVATQDVEVGGCPISKGERVSPLLGAANTDPAEFPDPEIV 319 Query 324 VMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSF 383 +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 320 DFTRSPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYEIRP--GTQLTYTAALR 377 Query 384 ALKNLPL 390 ++++LPL Sbjct 378 SVESLPL 384 >gi|296166114|ref|ZP_06848559.1| cytochrome P450 CYP254 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898523|gb|EFG78084.1| cytochrome P450 CYP254 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=389 Score = 229 bits (585), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 136/370 (37%), Positives = 204/370 (56%), Gaps = 12/370 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR+ PV L+R D+ AL++ ++FSS GN P++PL DPPEH Sbjct 22 YKALRETSPVFRSPQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRR+L P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRVLDPLFTPREMARREPGVTELVNEMIDRFAARGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPLED DR + WKD VI + DR H E+ A A+E+ +Y + E +P DV Sbjct 142 LPLEDLDRFLEWKDCVIRPEGDSGFDRRH--ESSAAVAQEIYDYFDRAIDEHIASPRDDV 199 Query 207 LSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPK 263 LS + + PLS E+L + L ++AGLDTVT ++ + LAR P R L + P+ Sbjct 200 LSAMIAADVAGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPDHRHQLVERPE 259 Query 264 QIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDEL 323 + +EE++R E P RV + V VGG + G V + A N D ++ + + Sbjct 260 VLPSAVEELLRWETPVPGVARVAIQDVEVGGCPISKGERVSPLLGAANTDPAEFADPELV 319 Query 324 VMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSF 383 +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 320 DFTRNPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYEIKP--GTQLTYTAALR 377 Query 384 ALKNLPLRWS 393 ++++LPL ++ Sbjct 378 SVESLPLVFA 387 >gi|41408077|ref|NP_960913.1| hypothetical protein MAP1979 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396432|gb|AAS04296.1| hypothetical protein MAP_1979 [Mycobacterium avium subsp. paratuberculosis K-10] Length=389 Score = 228 bits (582), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 139/367 (38%), Positives = 204/367 (56%), Gaps = 12/367 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR++ PV L+R D+ AL++ ++FSS GN P++PL DPP+H Sbjct 22 YKALRESNPVFRSTQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPDH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRRIL P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRILDPLFTPREMARREPLVTELVNEMIDRFAPRGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPLED DR + WKD VI + DR H + A VA +++ EY + E P DV Sbjct 142 LPLEDLDRFLLWKDGVIRPAGDSGFDRRHESSAGVA--QQIYEYFDKAIDEHIAVPRDDV 199 Query 207 LSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPK 263 LS + +G PLS E+L + L ++AGLDTVT ++ + LAR PQ R L + P Sbjct 200 LSAMIAADVGGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPQHRRQLVERPD 259 Query 264 QIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDEL 323 + +EE++R E P RV T+ V VGG + G V + A N D ++ + + Sbjct 260 VLPGAVEELLRWETPVPGVARVATQDVEVGGCPISKGERVSPLLGAANTDPAEFPDPEIV 319 Query 324 VMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSF 383 +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 320 DFTRSPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYEIRP--GTQLTYTAALR 377 Query 384 ALKNLPL 390 ++++LPL Sbjct 378 SVESLPL 384 >gi|297153658|gb|ADI03370.1| putative cytochrome P450 [Streptomyces bingchenggensis BCW-1] Length=382 Score = 224 bits (572), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 141/377 (38%), Positives = 204/377 (55%), Gaps = 10/377 (2%) Query 24 MAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVP 83 MA R W+ L M+ +T V A L+ P FS++KA P++P Sbjct 1 MAERRDDAWRMLMARPEPAPMDNGLAVTSLAAVKAVLKEPNRFSAKKAFDAVETGYPLIP 60 Query 84 LAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPF 143 LAFDPPE T YRRILQP+F P + SLR + +++A+ RG C+ +AD+A FP Sbjct 61 LAFDPPEQTHYRRILQPFFGPRRIRALEESLRAQAIDLVEAVKARGGCDFVADIAVPFPA 120 Query 144 QLFLVLYGLPLEDRDRLIGWKDAVIAMSD--------RPHPTEADVAAARELLEYLTAMV 195 Q L L GLPL DRDR I K+A + ++ A V L YL ++ Sbjct 121 QALLTLLGLPLADRDRFIESKNAALELTADAAGELTLTDEERAARVEQTMALGNYLGELI 180 Query 196 AERRRNPGPDVLSQVQI--GEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQ 253 RR PG D+LS++ G+D LS+ E +G+ +L+LAGL+TVT A+ ++ LA P Sbjct 181 QTRRAQPGDDILSEILAIDGDDHLSDTEAMGVCLMLVLAGLETVTDALSLAMERLATHPG 240 Query 254 LRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRD 313 R L ++P + +EE++RL+P AP PRVTTE V + G +PAG+ V + NRD Sbjct 241 RRRELVEDPSLVPAAVEELLRLDPPAPFLPRVTTEDVEIAGCPVPAGTLVNTHLTTANRD 300 Query 314 GSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYA 373 + ++ + H FG G HRCLG+HLARLE+ LL EW +IP++ +A + Sbjct 301 ETCWPRPHDIDFHRPDNPHTSFGVGVHRCLGTHLARLEMQLLFEEWHRRIPEYAIAEGTS 360 Query 374 PEIRFPSKSFALKNLPL 390 P R + +++L L Sbjct 361 PRARLVRANIGMESLRL 377 >gi|240171228|ref|ZP_04749887.1| cytochrome P450 superfamily protein [Mycobacterium kansasii ATCC 12478] Length=390 Score = 224 bits (571), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 136/370 (37%), Positives = 199/370 (54%), Gaps = 14/370 (3%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR++ PV L+R D+ AL+ +FSS GN P++PL DPPEH Sbjct 22 YKALRESTPVFRAPQAVVLSRLADIEMALKRTDLFSSNMDAVDLGNLRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRRIL P F+P +++ P + MID A RGEC+ A+ A P +FL L G Sbjct 82 AKYRRILDPLFTPREMARREPYVTELVNEMIDRFAARGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI------AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPD 205 LPLED D+ + WKD VI DR +A A+++ EY + + NP D Sbjct 142 LPLEDLDKFLEWKDGVIRPAGSTGYDDR---HDASAGVAQQIYEYFDRAIDDHVANPRDD 198 Query 206 VLSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNP 262 VLS + QI +PLS E+L + L ++AGLDTVT ++ + LAR P+ R L + P Sbjct 199 VLSAMIAAQIAGEPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPEHRRQLIEQP 258 Query 263 KQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDE 322 + +EE++R E P RV V VGG + G V + A N D ++ + Sbjct 259 DILPHAVEELLRWETPVPGVARVAMRDVEVGGCPISKGERVSPLLGAANTDPAEFPDPEL 318 Query 323 LVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKS 382 + +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+E+ P ++ + + Sbjct 319 VDFTRNPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYEIKP--GTQLVYTAAL 376 Query 383 FALKNLPLRW 392 +++ LPL + Sbjct 377 RSVQALPLTF 386 >gi|342857247|ref|ZP_08713903.1| cytochrome P450 superfamily protein [Mycobacterium colombiense CECT 3035] gi|342134580|gb|EGT87746.1| cytochrome P450 superfamily protein [Mycobacterium colombiense CECT 3035] Length=392 Score = 219 bits (559), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 135/370 (37%), Positives = 202/370 (55%), Gaps = 15/370 (4%) Query 32 WKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 +K LR+ PV L+R D+ AL++ ++FSS GN P++PL DPPEH Sbjct 22 YKALRETTPVFRSPQAVVLSRLADIEMALKHTELFSSNMDAVDLGNVRPLIPLQIDPPEH 81 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 +YRR+L P F+P +++ P + MID AGRGEC+ A+ A P +FL L G Sbjct 82 AKYRRVLDPLFTPREMARREPRVTELVNEMIDRFAGRGECDFHAEFAVPLPCTVFLQLLG 141 Query 152 LPLEDRDRLIGWKDAVI-----AMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDV 206 LPL+D +R + WKD VI + DR H E+ A A+++ EY + + P DV Sbjct 142 LPLDDLERFLVWKDGVIRPEGDSGFDRRH--ESSAAVAQQIYEYFDRAIDDHIARPRDDV 199 Query 207 LSQV---QIGED---PLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRD 260 LS + +D PLS E+L + L ++AGLDTVT ++ + LAR P R L + Sbjct 200 LSAMIAANFKDDAGQPLSREELLDICFLFLIAGLDTVTDSLDCFFVYLARHPGHRRQLVE 259 Query 261 NPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMST 320 P + +EE++R E P RV + V VGG + G V + A N D ++ Sbjct 260 QPDVLPGAVEELLRWETPVPGVARVAVQDVEVGGCPISKGERVSPLLGAANTDPAEFPDP 319 Query 321 DELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPS 380 + + +RH FGGGPHRCLGSHLAR+EL + + E+ +IPD+++ P E+ + + Sbjct 320 ELVDFTRNPNRHRAFGGGPHRCLGSHLARMELRVALREFHRRIPDYQIKP--GTELCYTA 377 Query 381 KSFALKNLPL 390 ++++LPL Sbjct 378 ALRSVESLPL 387 >gi|111017415|ref|YP_700387.1| cytochrome P450 [Rhodococcus jostii RHA1] gi|110816945|gb|ABG92229.1| cytochrome P450 CYP254 [Rhodococcus jostii RHA1] Length=412 Score = 214 bits (545), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 136/381 (36%), Positives = 203/381 (54%), Gaps = 31/381 (8%) Query 35 LRDAGPVVF---MNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPL-----PVVPLAF 86 LR GPV++ G + +TR ++ L L++P+ FSS P N L +PL Sbjct 37 LRKQGPVLYSPHHGGHWVVTRYKEALQVLQDPETFSSF-----PNNLLNAAQGKFLPLEL 91 Query 87 DPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLF 146 DPPEH+ YR+ LQP FSP + P +R+ +ID A RGECE +++ A+ P ++F Sbjct 92 DPPEHSYYRQALQPLFSPKQMKALEPEIRKIITELIDQFADRGECEFISEFAHELPTRIF 151 Query 147 LVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAAR-----ELLEYLTAMVAERRRN 201 L L G PL D + W D I + P +EA+ A AR E+ EY +VA R Sbjct 152 LALMGWPLSDAPQFTEWTD--ITLQGIPGASEAESAEARAKAAGEIYEYFGKVVARVRSG 209 Query 202 PGPDVLSQVQIGEDPL---------SEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRP 252 QI PL ++ E+ + LL++AGL TV A+ + L+ L+ Sbjct 210 EDSSESLTAQIINTPLDIDGTPRSLTDEELSRMFFLLLVAGLHTVQGALAWGLIHLSHNL 269 Query 253 QLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNR 312 + R + D+P I +EEI+R+E +A + R T +GG+++ AG + + M + NR Sbjct 270 EQREAIIDDPTLIPSAVEEILRIE-TATSSGRRATRDAEIGGVSIKAGDQLLVVMTSANR 328 Query 313 DGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDY 372 D + S +EL ++ +RH GFG GPHRCLGSHLARLEL L + E +IPD+ L PD Sbjct 329 DNDEFDSPEELQIERHPNRHIGFGAGPHRCLGSHLARLELRLAMEEIHRRIPDYALVPD- 387 Query 373 APEIRFPSKSFALKNLPLRWS 393 P + S+ + LP+ ++ Sbjct 388 NPAVFHSSQVRGCEKLPITFT 408 >gi|334344633|ref|YP_004553185.1| Camphor 5-monooxygenase [Sphingobium chlorophenolicum L-1] gi|334101255|gb|AEG48679.1| Camphor 5-monooxygenase [Sphingobium chlorophenolicum L-1] Length=408 Score = 210 bits (534), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 128/369 (35%), Positives = 197/369 (54%), Gaps = 21/369 (5%) Query 39 GPVVFMN--------GWYYLTRREDVLAALRNPKVFSSRKAL--QPPGNPLPVVPLAFDP 88 GP +F + G + +TR +D L++P+ FSS +++ G P++PL DP Sbjct 47 GPRIFYSPVNTRDGRGTWVITRAQDQRRVLQDPESFSSHRSIFASALGESWPMIPLELDP 106 Query 89 PEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRG-ECEAMADLANLFPFQLFL 147 P+H ++R +L P SP + ++R V +ID IA G C M D A F +FL Sbjct 107 PDHGKFRSLLNPLLSPKRVMALESAVRERAVFLIDRIAAAGTSCHVMEDFAFPFAVNIFL 166 Query 148 VLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDVL 207 GLP + D + W + ++ + P AAAR ++ ++ + AERR+ P D + Sbjct 167 RFLGLPDDRLDEFVTWANELLHGDNVQRP-----AAARTIIAFIDELAAERRKRPVDDFM 221 Query 208 S---QVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQ 264 S Q +I + PL++ E+ G LL +AGLDTV AA+GF L LAR P+ + MLR +P + Sbjct 222 SFLVQSKIDDRPLTDTEIRGTGVLLFVAGLDTVAAAIGFDLNYLARHPEDQEMLRGDPSR 281 Query 265 IRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELV 324 I + EE++R P+ + RV T+ + G + G V NRD + +++ Sbjct 282 IVLAAEELLRAYPTVQMI-RVATKDIDFEGAPIRKGDHVSCATMIANRDPLEFPHPEKID 340 Query 325 MDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFA 384 + + +RH F GPHRCLGSHLAR E+ + + EWL +IP F + AP + F F Sbjct 341 LTREDNRHTAFAYGPHRCLGSHLARREIVVGLEEWLKRIPPFRIKEGTAP-VAFGGHVFG 399 Query 385 LKNLPLRWS 393 ++NL L WS Sbjct 400 IENLILDWS 408 >gi|111017445|ref|YP_700417.1| cytochrome P450 [Rhodococcus jostii RHA1] gi|110816975|gb|ABG92259.1| cytochrome P450 CYP254 [Rhodococcus jostii RHA1] Length=409 Score = 208 bits (530), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 128/357 (36%), Positives = 192/357 (54%), Gaps = 20/357 (5%) Query 35 LRDAGPVVFMN---GWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEH 91 LR GPVV+ G + +TR E++ LR+P+ FSS +P+ DPPEH Sbjct 35 LRAIGPVVYSKAHGGHWIVTRYEEIHQVLRDPETFSSYPNNLVNAGQGKFIPIELDPPEH 94 Query 92 TRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYG 151 T YR+ LQP FSP + + P +R +ID A RGE E +++ A+ P ++FL L G Sbjct 95 TYYRQALQPLFSPKRMKELEPRIRDVINELIDDFAARGEAEFISEFAHELPTRVFLALMG 154 Query 152 LPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARE-----LLEYLTAMVAERRRNPGPDV 206 PLED + D +A+ P TE + A ARE + Y A+VA R Sbjct 155 WPLEDAEMFTTTTD--VALQGVPGGTEEESATAREAAANQIFGYFGAIVAGVRSGEITSD 212 Query 207 LSQVQIGEDP---------LSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAM 257 QI P L++ E+ + LL++AGL TV ++ ++++ LA P R Sbjct 213 TLTAQIINAPIEMGDGVRLLTDEELYRMFFLLLIAGLHTVQGSLAWAIIHLANNPGQRQE 272 Query 258 LRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDA 317 + D+P + +EEI+R+E +A +A R T V +GG+T+ G + + + + NRDG++ Sbjct 273 IVDDPDTVSAAVEEILRIE-AAVIAGRRATRDVEIGGVTIREGDQLIVLLCSANRDGAEF 331 Query 318 MSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAP 374 DEL +D +RH FG GPHRC+GSHLAR+EL L + E ++PD+ L P+ P Sbjct 332 EDPDELRVDRSPNRHLSFGAGPHRCIGSHLARIELKLAMEEIHKRLPDYRLVPEDPP 388 >gi|111223235|ref|YP_714029.1| putative camphor 5-monooxygenase [Frankia alni ACN14a] gi|111150767|emb|CAJ62469.1| putative Camphor 5-monooxygenase (P450cam) [Frankia alni ACN14a] Length=415 Score = 207 bits (528), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 126/351 (36%), Positives = 191/351 (55%), Gaps = 15/351 (4%) Query 32 WKTLRDAGPVVF---MNGWYYLTRREDVLAALRNPKVFSSRKALQPP--GNPLPVVPLAF 86 + LR PV + GW + RR ++ LRNP+VFS+ L P +PLP +P+ Sbjct 40 FSRLRAKCPVDYDEGHEGWIQILRRAEIDEVLRNPEVFSN---LIPELMSSPLPAIPMGV 96 Query 87 DPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLF 146 DPP+H +YRRIL P FSP ++ + +TVA I++ RG C+ DLA P +F Sbjct 97 DPPDHAKYRRILDPLFSPRRMAALEAEVVANTVATIESFLDRGSCDFATDLAVPLPCSVF 156 Query 147 LVLYGLPLEDRDRLIGWKDAVI---AMSDRP-HPTEADVAAARELLEYLTAMVAERRRNP 202 L L+GLP + L+ KDA+I +++D P A ++ ++A+RR P Sbjct 157 LTLFGLPQSELPGLLHMKDALIRPESLTDDPDEKLRIQTEAGTQVFTLFGTVLAQRRAEP 216 Query 203 GPDVLSQV---QIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLR 259 D+++++ +I PL+E E+LG+ +L++AGLDTVT ++ L L P+ R + Sbjct 217 RDDLITELLKAEIEGRPLTEPELLGICFMLMMAGLDTVTISLTCILAYLLEHPEARQRIV 276 Query 260 DNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMS 319 +P+ I +EE++R E PR+ T V G + G V + +A+ N D Sbjct 277 ADPETIPAIVEELLRWETPVMAVPRIVTRDTEVAGCPVRKGEMVHVMLASGNLDPDADPR 336 Query 320 TDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAP 370 + +D RH FGGGPHRCLGSHLAR+EL ++ EW IP++ LAP Sbjct 337 AGVVDLDRADKRHLAFGGGPHRCLGSHLARMELRTVLREWHRLIPEYSLAP 387 Lambda K H 0.322 0.139 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 767373824232 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40