BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1789

Length=393
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|57116911|ref|YP_177835.1|  PPE family protein [Mycobacterium t...   741    0.0   
gi|15841257|ref|NP_336294.1|  PPE family protein [Mycobacterium t...   741    0.0   
gi|31792977|ref|NP_855470.1|  PPE family protein [Mycobacterium b...   740    0.0   
gi|289569854|ref|ZP_06450081.1|  PPE family protein [Mycobacteriu...   740    0.0   
gi|289745779|ref|ZP_06505157.1|  PPE family protein [Mycobacteriu...   740    0.0   
gi|254364621|ref|ZP_04980667.1|  PPE family protein [Mycobacteriu...   543    2e-152
gi|340626801|ref|YP_004745253.1|  PPE family protein [Mycobacteri...   516    3e-144
gi|183981917|ref|YP_001850208.1|  PPE family protein [Mycobacteri...   382    4e-104
gi|296167733|ref|ZP_06849950.1|  PPE family protein [Mycobacteriu...   372    7e-101
gi|240172022|ref|ZP_04750681.1|  PPE family protein [Mycobacteriu...   360    2e-97 
gi|289574372|ref|ZP_06454599.1|  PPE family protein [Mycobacteriu...   359    3e-97 
gi|15841163|ref|NP_336200.1|  PPE family protein [Mycobacterium t...   348    9e-94 
gi|31792891|ref|NP_855384.1|  PPE family protein [Mycobacterium b...   348    1e-93 
gi|57116898|ref|YP_177827.1|  PPE family protein [Mycobacterium t...   347    3e-93 
gi|289745858|ref|ZP_06505236.1|  PPE family protein [Mycobacteriu...   346    3e-93 
gi|340626711|ref|YP_004745163.1|  PPE family protein [Mycobacteri...   345    7e-93 
gi|254550715|ref|ZP_05141162.1|  PPE family protein [Mycobacteriu...   344    1e-92 
gi|121637612|ref|YP_977835.1|  PPE family protein [Mycobacterium ...   344    1e-92 
gi|240171295|ref|ZP_04749954.1|  PPE family protein [Mycobacteriu...   342    5e-92 
gi|307079711|ref|ZP_07488881.1|  PPE family protein [Mycobacteriu...   327    2e-87 
gi|118617327|ref|YP_905659.1|  PPE family protein [Mycobacterium ...   314    2e-83 
gi|167969175|ref|ZP_02551452.1|  PPE family protein [Mycobacteriu...   310    2e-82 
gi|183982531|ref|YP_001850822.1|  PPE family protein [Mycobacteri...   301    1e-79 
gi|240170165|ref|ZP_04748824.1|  PPE family protein [Mycobacteriu...   301    1e-79 
gi|183981114|ref|YP_001849405.1|  PPE family protein [Mycobacteri...   301    2e-79 
gi|118616629|ref|YP_904961.1|  PPE family protein [Mycobacterium ...   295    1e-77 
gi|342861308|ref|ZP_08717956.1|  PPE family protein [Mycobacteriu...   293    5e-77 
gi|240171969|ref|ZP_04750628.1|  PPE family protein [Mycobacteriu...   291    1e-76 
gi|212596789|gb|ACJ35606.1|  PPE45 [Mycobacterium intracellulare ...   285    1e-74 
gi|183982678|ref|YP_001850969.1|  PPE family protein, PPE26 [Myco...   284    1e-74 
gi|158667960|gb|ABW76444.1|  PPE family protein [Mycobacterium av...   278    8e-73 
gi|118618470|ref|YP_906802.1|  PPE family protein [Mycobacterium ...   277    3e-72 
gi|240167786|ref|ZP_04746445.1|  PPE family protein [Mycobacteriu...   273    3e-71 
gi|342861306|ref|ZP_08717954.1|  PPE family protein [Mycobacteriu...   270    3e-70 
gi|254821314|ref|ZP_05226315.1|  PPE family protein [Mycobacteriu...   259    5e-67 
gi|118466367|ref|YP_882110.1|  PPE family protein [Mycobacterium ...   252    7e-65 
gi|158667958|gb|ABW76443.1|  PPE family protein [Mycobacterium av...   251    1e-64 
gi|118464959|ref|YP_882112.1|  PPE family protein [Mycobacterium ...   251    2e-64 
gi|212596061|gb|ACJ35548.1|  PPE23 [Mycobacterium avium subsp. av...   251    2e-64 
gi|158667962|gb|ABW76445.1|  PPE family protein [Mycobacterium av...   249    7e-64 
gi|342861307|ref|ZP_08717955.1|  PPE family protein [Mycobacteriu...   248    2e-63 
gi|41407604|ref|NP_960440.1|  hypothetical protein MAP1506 [Mycob...   245    1e-62 
gi|240172861|ref|ZP_04751520.1|  PPE family protein, PPE31 [Mycob...   239    5e-61 
gi|254821012|ref|ZP_05226013.1|  PPE family protein, PPE31 [Mycob...   238    1e-60 
gi|289446957|ref|ZP_06436701.1|  PPE family protein [Mycobacteriu...   238    2e-60 
gi|183981478|ref|YP_001849769.1|  PPE family protein [Mycobacteri...   237    2e-60 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   236    5e-60 
gi|306784092|ref|ZP_07422414.1|  PPE family protein [Mycobacteriu...   236    6e-60 
gi|308231818|ref|ZP_07413879.2|  PPE family protein [Mycobacteriu...   235    1e-59 
gi|289554847|ref|ZP_06444057.1|  PPE family protein [Mycobacteriu...   235    1e-59 


>gi|57116911|ref|YP_177835.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|121637690|ref|YP_977913.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|148661596|ref|YP_001283119.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 51 more sequence titles
 Length=393

 Score =  741 bits (1914),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/393 (100%), Positives = 393/393 (100%), Gaps = 0/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393


>gi|15841257|ref|NP_336294.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881484|gb|AAK46108.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=411

 Score =  741 bits (1914),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/393 (100%), Positives = 393/393 (100%), Gaps = 0/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  19   MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  78

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  79   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  138

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  139  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  198

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  199  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  258

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  259  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  318

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  319  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  378

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  379  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  411


>gi|31792977|ref|NP_855470.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|31618568|emb|CAD94520.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
Length=393

 Score =  740 bits (1911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/393 (99%), Positives = 393/393 (100%), Gaps = 0/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQ+AKTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQAAKTLGLIGSAAPAAVAAAGDAAKGLP  300

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393


>gi|289569854|ref|ZP_06450081.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289543608|gb|EFD47256.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=393

 Score =  740 bits (1911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/393 (99%), Positives = 392/393 (99%), Gaps = 0/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQS KTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSTKTLGLIGSAAPAAVAAAGDAAKGLP  300

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393


>gi|289745779|ref|ZP_06505157.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|339631843|ref|YP_004723485.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|289686307|gb|EFD53795.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|339331199|emb|CCC26881.1| PPE family protein [Mycobacterium africanum GM041182]
Length=393

 Score =  740 bits (1911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/393 (99%), Positives = 392/393 (99%), Gaps = 0/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAA QAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAATQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393


>gi|254364621|ref|ZP_04980667.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|134150135|gb|EBA42180.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
Length=391

 Score =  543 bits (1398),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 391/393 (99%), Positives = 391/393 (99%), Gaps = 2/393 (0%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
            TQA  VATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI
Sbjct  181  TQA--VATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  238

Query  241  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  300
            SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP
Sbjct  239  SALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAKGLP  298

Query  301  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  360
            GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS
Sbjct  299  GLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAAPGS  358

Query  361  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  359  LLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  391


>gi|340626801|ref|YP_004745253.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004991|emb|CCC44139.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=397

 Score =  516 bits (1328),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 392/397 (99%), Positives = 392/397 (99%), Gaps = 4/397 (1%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL
Sbjct  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG
Sbjct  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180

Query  181  TQAAAVATAAGTAQ----STLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQAAAVATAAGTA     STLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF
Sbjct  181  TQAAAVATAAGTAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  240

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
            PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA
Sbjct  241  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  300

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEA  356
            KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEA
Sbjct  301  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEA  360

Query  357  APGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            APGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG
Sbjct  361  APGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  397


>gi|183981917|ref|YP_001850208.1| PPE family protein [Mycobacterium marinum M]
 gi|183175243|gb|ACC40353.1| PPE family protein [Mycobacterium marinum M]
Length=398

 Score =  382 bits (982),  Expect = 4e-104, Method: Compositional matrix adjust.
 Identities = 237/402 (59%), Positives = 285/402 (71%), Gaps = 13/402 (3%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFG  PPEV S  MY GPGS  M AAAS WN +AAEL SAAT YE+++  L  EGWLGP
Sbjct  1    MDFGRRPPEVTSALMYMGPGSTSMTAAASVWNRVAAELDSAATSYESLVIGLVEEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS AMA+AVAPYV WM A AAQAE  A QARA+AAA+E AF A VPPPLI+ANR  L +L
Sbjct  61   ASVAMADAVAPYVVWMRATAAQAEHTAMQARASAAAYETAFGAVVPPPLISANRVRLAEL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            I++NVFGQNT+ I A E +YG+MWAQD+AAMY YA +++SA+ +TPF+ P QI +P A  
Sbjct  121  IASNVFGQNTAVITALETEYGQMWAQDAAAMYEYAAATSSATELTPFTQPQQIVSPGAGS  180

Query  181  TQAAAV----ATAAGTAQSTLTEMITGLPNALQSLTSPLLQSS--NGPLSWLWQILFGTP  234
             Q AAV    AT AGT+Q+TL+ +I+ +P AL  + +PL  S+  + PL WLWQILFGT 
Sbjct  181  GQIAAVAHSAATLAGTSQTTLSRLISEIPKALHGIVAPLAASTTPDSPLGWLWQILFGT-  239

Query  235  NFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGD  294
             FPTSISALLTDLQPYASFFYNTEGLPYFSIGM NNFIQ +KTLGL+     AA   A  
Sbjct  240  TFPTSISALLTDLQPYASFFYNTEGLPYFSIGMANNFIQMSKTLGLLSGTTAAATGGAAS  299

Query  295  AAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAP  354
               G    G + GGG V+A LG+AAS+G+LSVPP W+  +P  +    A +P+ T+  AP
Sbjct  300  GLAG--LGGLIDGGGQVSAHLGHAASLGRLSVPPSWAQSVP-DLESMPARMPIETLKFAP  356

Query  355  E---AAPGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            +   A        L   G G +G+GPRYG RPTVMARPPFAG
Sbjct  357  DGGGAGNLLGGMPLGGPGLGASGSGPRYGVRPTVMARPPFAG  398


>gi|296167733|ref|ZP_06849950.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897076|gb|EFG76691.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=406

 Score =  372 bits (955),  Expect = 7e-101, Method: Compositional matrix adjust.
 Identities = 233/407 (58%), Positives = 275/407 (68%), Gaps = 16/407 (3%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DFGA PPE NS RMY GPG   + AAASAWNGLAAEL+S A GY+ VIT LS E WLGP
Sbjct  2    IDFGAAPPEYNSARMYTGPGPEALTAAASAWNGLAAELNSTALGYDKVITALSGEEWLGP  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA+AVAPYVAWM   AAQAEQ A Q  AAA A+E A AATVPPPL+AANRA   QL
Sbjct  62   ASASMAQAVAPYVAWMRTTAAQAEQTANQMHAAATAYETALAATVPPPLVAANRAQTAQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++TNV G NT AIA  EAQYGEMWAQD++ MY+YAG SA+A+ V PF+  PQIANP+AQ 
Sbjct  122  LATNVLGLNTPAIAQLEAQYGEMWAQDASTMYSYAGQSAAATKVAPFTAAPQIANPSAQA  181

Query  181  TQAAAVATAAGTA-----QSTLTEMITGLPNALQSLTSP-LLQSS--NGPLSWLWQILFG  232
            TQ  AVA A G +     QS L+  ++  PN LQ+L +P   QSS  + P S +W +L G
Sbjct  182  TQGTAVANATGNSAASSTQSVLSHAVSSTPNTLQALAAPAATQSSTTSAPFSEIWYLLTG  241

Query  233  TPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAA  292
                PTS+ + +    P+++ +YNTEGLPYFS+GMGN  +Q AKT GL+  AAP AV A 
Sbjct  242  QTTLPTSLGSFVNGYNPFSALWYNTEGLPYFSVGMGNFGVQIAKTTGLLNGAAP-AVKAL  300

Query  293  GDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPLPVSTVS  351
                     LGG       AA LGNAASV G+LSVP  WS     +   G A +PVSTVS
Sbjct  301  PGLGGLGGLLGGGATAAHPAAALGNAASVGGRLSVPVSWSAASTPAPVLGQA-IPVSTVS  359

Query  352  AAPE--AAPGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            AAP+  AAPG+LL           G AG GP+YGFRPTVMARPPF G
Sbjct  360  AAPDATAAPGNLLGGMPLAGAGAGGHAGVGPKYGFRPTVMARPPFGG  406


>gi|240172022|ref|ZP_04750681.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=365

 Score =  360 bits (924),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 249/366 (69%), Positives = 280/366 (77%), Gaps = 15/366 (4%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY+GPGSAPM AAA+AWN LA ELSSAA GYE V+TQLSSE W+GP
Sbjct  1    MDFGALPPEVNSGRMYSGPGSAPMAAAATAWNSLAVELSSAARGYEAVVTQLSSEEWMGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MAEAVAPYVAW  AAA  AEQAA QARAAAAAFE AFAA VPPPLIAANRA L Q 
Sbjct  61   ASATMAEAVAPYVAWTGAAATHAEQAAAQARAAAAAFETAFAAVVPPPLIAANRAQLAQA  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPT---  177
            I+TNVFGQNTS IAA EAQYGEMWAQD+AAMY+YAG+SA A+AVTPF++PPQI +PT   
Sbjct  121  IATNVFGQNTSVIAALEAQYGEMWAQDAAAMYSYAGNSAHAAAVTPFTSPPQITSPTAQA  180

Query  178  -AQGTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPL----------LQSSNGPLSWL  226
                  AAA  T+AG+AQ TL + ++ +P  L  L +P+          LQS+ GPL+ L
Sbjct  181  GQTAAVAAATGTSAGSAQQTLNQFLSAIPTTLGGLAAPVTGPIGTEVGFLQSAQGPLTGL  240

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            WQ+LFGT  FP SIS  LT   PYA FFYNTEGLPYFSIGM NNF+QSAKTLGLIG +A 
Sbjct  241  WQVLFGTSTFPNSISGFLTAYTPYAGFFYNTEGLPYFSIGMANNFVQSAKTLGLIGGSA-  299

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLP  346
             A AA   A       G + GGG V+ GLGNAASVGKLSVPPVWSG LPG++ PG APLP
Sbjct  300  PAAAAGAAAKGLPGLGGLLGGGGSVSGGLGNAASVGKLSVPPVWSGQLPGAMHPGGAPLP  359

Query  347  VSTVSA  352
            VS ++A
Sbjct  360  VSAITA  365


>gi|289574372|ref|ZP_06454599.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538803|gb|EFD43381.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=384

 Score =  359 bits (922),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 242/403 (61%), Positives = 281/403 (70%), Gaps = 29/403 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IGS    +  AA   +
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGSRGRRSCRAARRPS  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLSVPP W+G  P    +V   +APL VS +   
Sbjct  289  ------ARVCGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  341

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  342  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  384


>gi|15841163|ref|NP_336200.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881383|gb|AAK46014.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|323719795|gb|EGB28909.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=385

 Score =  348 bits (893),  Expect = 9e-94, Method: Compositional matrix adjust.
 Identities = 245/403 (61%), Positives = 282/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLS+PP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPLA--GAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PLA  G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGMGGAGPRYGFRVTVMSRPPFAG  385


>gi|31792891|ref|NP_855384.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|224990087|ref|YP_002644774.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|289443162|ref|ZP_06432906.1| PPE family protein [Mycobacterium tuberculosis T46]
 18 more sequence titles
 Length=385

 Score =  348 bits (893),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 245/403 (61%), Positives = 282/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLSVPP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|57116898|ref|YP_177827.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661502|ref|YP_001283025.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148822911|ref|YP_001287665.1| PPE family protein [Mycobacterium tuberculosis F11]
 39 more sequence titles
 Length=385

 Score =  347 bits (889),  Expect = 3e-93, Method: Compositional matrix adjust.
 Identities = 244/403 (61%), Positives = 282/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLS+PP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|289745858|ref|ZP_06505236.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289686386|gb|EFD53874.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=385

 Score =  346 bits (888),  Expect = 3e-93, Method: Compositional matrix adjust.
 Identities = 244/403 (61%), Positives = 282/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AM+ YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMHGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLSVPP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|340626711|ref|YP_004745163.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004901|emb|CCC44047.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=385

 Score =  345 bits (885),  Expect = 7e-93, Method: Compositional matrix adjust.
 Identities = 245/403 (61%), Positives = 281/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLSVPP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL   G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGPGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|254550715|ref|ZP_05141162.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
Length=385

 Score =  344 bits (883),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 243/403 (61%), Positives = 281/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+ G+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFATGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLS+PP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|121637612|ref|YP_977835.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|121493259|emb|CAL71730.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
Length=385

 Score =  344 bits (883),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 244/403 (61%), Positives = 281/403 (70%), Gaps = 28/403 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            M FGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MAFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLSVPP W+G  P    +V   +APL VS +   
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
            PEA A G+LLGG+PL  +G G  GAGPRYGFR TVM+RPPFAG
Sbjct  343  PEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSRPPFAG  385


>gi|240171295|ref|ZP_04749954.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=400

 Score =  342 bits (878),  Expect = 5e-92, Method: Compositional matrix adjust.
 Identities = 245/402 (61%), Positives = 286/402 (72%), Gaps = 11/402 (2%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MD+G LPPEVNS RMY GPGS  M AAASAW+ LAAEL SAA GYET++ QL+ EGWLGP
Sbjct  1    MDYGGLPPEVNSARMYTGPGSMSMTAAASAWSALAAELDSAAAGYETLVDQLAGEGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS AMA AVAPYV WM A AAQAEQ A QARAAAAA+E A AA VPPP I ANR  L +L
Sbjct  61   ASTAMAAAVAPYVVWMRATAAQAEQTAMQARAAAAAYENAVAAMVPPPAILANRLQLAEL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            + +NV+GQNTSAIAA EAQYG+MWAQD+ AMY YA ++ SA+ +TPF+ PP I NP    
Sbjct  121  MQSNVYGQNTSAIAALEAQYGQMWAQDATAMYEYAAATGSATTLTPFNQPPHIVNPAGAS  180

Query  181  TQ----AAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQS-SNGPLSWLWQILFGTPN  235
             Q      A AT+AG +QS L  +I+G+P  LQ L +P+  + S+ PL+WLWQILFGT  
Sbjct  181  GQTAAVTHAAATSAGASQSALARLISGIPTMLQGLATPVASAVSSSPLAWLWQILFGTST  240

Query  236  FPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDA  295
            FPTSI+ALLTDLQPYASF YNTEGLPYFSIGM NNF+QS+KTLGL+G  A AA A     
Sbjct  241  FPTSIAALLTDLQPYASFLYNTEGLPYFSIGMANNFVQSSKTLGLLGGTA-AAAAGGAAQ  299

Query  296  AKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPE  355
                     + GGGPV+AGLG+A S+G+LSVPP W+  LP  V    A +PV T   AP+
Sbjct  300  GGLAGLGSLVGGGGPVSAGLGHAGSIGRLSVPPSWAQALP-DVESIPARMPVETFKFAPD  358

Query  356  AA----PGSLLGGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            AA        +      G G  G+GPRYG RPTVMARPPFAG
Sbjct  359  AAGSGNLLGGMPLGGPMGHGATGSGPRYGVRPTVMARPPFAG  400


>gi|307079711|ref|ZP_07488881.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308362459|gb|EFP51310.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=376

 Score =  327 bits (838),  Expect = 2e-87, Method: Compositional matrix adjust.
 Identities = 230/386 (60%), Positives = 267/386 (70%), Gaps = 27/386 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPG---SVTPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLS+PP W+G  P    +V   +APL VS +   
Sbjct  289  GAA-----VGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPL-VSDIVEQ  342

Query  354  PEA-APGSLLGGLPLAGAGGAGAGPR  378
            PEA A G+LLGG+PLAG+ G G G R
Sbjct  343  PEAGAAGNLLGGMPLAGS-GTGTGVR  367


>gi|118617327|ref|YP_905659.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118569437|gb|ABL04188.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=392

 Score =  314 bits (804),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 229/407 (57%), Positives = 269/407 (67%), Gaps = 29/407 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGS PMV+AASAWN LA+ELS  A GYE VI  LS E W GP
Sbjct  1    MDFGALPPEVNSGRMYTGPGSTPMVSAASAWNRLASELSFTADGYERVIKALSGEEWFGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA M EA+ PYV WM + A QAE+AA QA AA AAFEAAF   VPPPLIA+NR  LM L
Sbjct  61   ASAMMLEAITPYVTWMRSTAVQAERAAKQAEAAVAAFEAAFTGVVPPPLIASNRMQLMTL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ N++GQ T+ IA+ EAQY EMWAQD+ AMY YAGSSASA+ +T F+ PP+ ANP A  
Sbjct  121  MARNIYGQYTAEIASLEAQYAEMWAQDARAMYTYAGSSASATKITAFTPPPETANPAASA  180

Query  181  TQA----AAVATAAGTAQSTLTEMITGLPNALQSLTSPL---LQSSNGPLSWLWQILFGT  233
             Q+     A ATAAG AQSTL  +I+ LPNAL SLTSP+   L S+  P +W        
Sbjct  181  LQSNATSTAAATAAGAAQSTLAGVISQLPNALTSLTSPIASALTSAASPATW--------  232

Query  234  PNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLI-GSAAPAAVAAA  292
                  I  L+    P +  FYNT GLPYF+IG+G++ I S + LGLI   A  AA  A 
Sbjct  233  ------IDWLVNWYLPISQLFYNTVGLPYFAIGIGSSLITSERALGLIGPEAEAAAAGAG  286

Query  293  GDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSG---PLPGSVTPGAAPLPVST  349
               A        + G GP+ AGLGNA+++GKLSVPP W G    +P SV+ G  PL    
Sbjct  287  AAEAAAGAAPAALGGAGPIGAGLGNASALGKLSVPPSWPGSGLDVPPSVSAG-GPLASDI  345

Query  350  VSAAPEAAPGSLLGGLPL---AGAGGAGAGPRYGFRPTVMARPPFAG  393
            V+    +APGSLLGG+PL    G   AGAGPRYGFR TVMARPPFAG
Sbjct  346  VNPPEASAPGSLLGGMPLAGGPGGAAAGAGPRYGFRVTVMARPPFAG  392


>gi|167969175|ref|ZP_02551452.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=356

 Score =  310 bits (795),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 213/358 (60%), Positives = 248/358 (70%), Gaps = 22/358 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGSAPMVAAASAWNGLAAELS AA GYE VIT L +E WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPYVAWM A A QAEQAA+QARAAAAA+E AFAA VPPPLIAANRA L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ NVFGQNT++IAA EAQY EMWAQD+ AMY YAGSSA+A+ VTPF+ PP   +P+A  
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  TQAAAVATAAGT----AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ +AVA AAGT    AQS + E+I  LPN L  LTSPL  +              TP +
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA---------ATPGW  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAA  296
               +   +    P +  FYNT GLPYF+IG+GN+ I S + LG IG  A  A AAA  A 
Sbjct  232  ---LEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGPEAAEAAAAAPAAV  288

Query  297  KGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSV-TPGAAPLPVSTVSAA  353
                    + G GPV+AGLGNAA++GKLS+PP W+G  P    T G+A  P S +S++
Sbjct  289  G-----AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPWSAISSS  341


>gi|183982531|ref|YP_001850822.1| PPE family protein [Mycobacterium marinum M]
 gi|183175857|gb|ACC40967.1| PPE family protein [Mycobacterium marinum M]
Length=392

 Score =  301 bits (772),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 229/407 (57%), Positives = 269/407 (67%), Gaps = 29/407 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS RMY GPGS PMV+AASAWN LA+ELS  A GYE VI  LS E W GP
Sbjct  1    MDFGALPPEVNSGRMYTGPGSTPMVSAASAWNRLASELSFTADGYERVIKALSGEEWFGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA M EA+ PYV WM + A QAEQAA QA AA AAFEAAF   VPPPLIA+NR  LM L
Sbjct  61   ASAMMLEAITPYVTWMRSTAVQAEQAAKQAEAAVAAFEAAFTGVVPPPLIASNRMQLMTL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++ N++GQ T+ IA+ EAQ  EMWAQD+ AMY YAGSSASA+ +T F+ PP+ ANP A  
Sbjct  121  MARNIYGQYTAEIASLEAQDAEMWAQDARAMYTYAGSSASATKITAFTPPPETANPAASA  180

Query  181  TQA----AAVATAAGTAQSTLTEMITGLPNALQSLTSPL---LQSSNGPLSWLWQILFGT  233
             Q+     A ATAAG AQSTL  +I+ LPNAL SLTSP+   L S+  P +W        
Sbjct  181  LQSNATSTAAATAAGAAQSTLAGVISQLPNALTSLTSPIASALTSAASPATW--------  232

Query  234  PNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLI-GSAAPAAVAAA  292
                  I  L+    P +  FYNT GLPYF+IG+G++ I S + LGLI   A  AA  A 
Sbjct  233  ------IDWLVNWYLPISQLFYNTVGLPYFAIGIGSSLITSERALGLIGPEAEAAAAGAG  286

Query  293  GDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSG---PLPGSVTPGAAPLPVST  349
               A        + G GP+ AGLGNA+++GKLSVPP W+G    +P SV+ G  PL    
Sbjct  287  AAEAAAGAAPAALGGAGPIGAGLGNASALGKLSVPPSWAGSGLDVPPSVSAG-GPLASDI  345

Query  350  VSAAPEAAPGSLLGGLPL---AGAGGAGAGPRYGFRPTVMARPPFAG  393
            V+    +APGSLLGG+PL    G   AGAGPRYGFR TVMARPPFAG
Sbjct  346  VNPPEASAPGSLLGGMPLAGGPGGAAAGAGPRYGFRVTVMARPPFAG  392


>gi|240170165|ref|ZP_04748824.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=393

 Score =  301 bits (771),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 238/402 (60%), Positives = 285/402 (71%), Gaps = 18/402 (4%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPEVNS R+YAGPGSAP+VAAASAW+GLA+ELSSAA GY+ V+T L +E WLGP
Sbjct  1    MDFGALPPEVNSGRLYAGPGSAPLVAAASAWSGLASELSSAADGYQRVVTTLHAEEWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS  M EAVAPY+AWM AAAAQAEQAA+QARAAAAAFE AFA+ VPPPLIAANRA L  L
Sbjct  61   ASTLMIEAVAPYLAWMRAAAAQAEQAASQARAAAAAFETAFASVVPPPLIAANRAQLASL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            I+ NV+GQ  +AIAA EAQY EMWAQD+ AMY+YAGSSASA+ +TP++ PP I +P A  
Sbjct  121  IAKNVYGQYGAAIAALEAQYAEMWAQDARAMYSYAGSSASAAQLTPYTPPPHITSPAAAA  180

Query  181  TQAA----AVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
            TQ+A    AVAT+AG AQ+TL+ +I+ LP+ L  L SP+  + N           G  + 
Sbjct  181  TQSAAVTQAVATSAGAAQNTLSGLISELPSMLLGLASPISSALNA---------GGLTSN  231

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP--AAVAAAGD  294
            P  +  L+    P +   YNT GLPYF+IG+GN+ I S + LG IG AA   +  +AA  
Sbjct  232  PGWLQWLIDWYMPISQLIYNTVGLPYFAIGIGNSLITSWRALGWIGPAASEISETSAAAA  291

Query  295  AAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWS-GPLPGSVTPGAAPLPVSTVSAA  353
            AA        + G GPV AGLGNA+++GKLSVPP WS  P PG     AAPL    V+  
Sbjct  292  AAAAGAAPAALGGAGPVTAGLGNASALGKLSVPPTWSANPGPGPAVADAAPLASDIVNPP  351

Query  354  PEAAPGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
               APGSLLGG+PL   GA  AGAGP+YGFR TVM+RPPFAG
Sbjct  352  EVGAPGSLLGGMPLAGPGAAAAGAGPKYGFRVTVMSRPPFAG  393


>gi|183981114|ref|YP_001849405.1| PPE family protein [Mycobacterium marinum M]
 gi|183174440|gb|ACC39550.1| PPE family protein [Mycobacterium marinum M]
Length=380

 Score =  301 bits (770),  Expect = 2e-79, Method: Compositional matrix adjust.
 Identities = 209/402 (52%), Positives = 264/402 (66%), Gaps = 31/402 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFG LPPE+NS RMY+GPGS+P++  ASAW+GLAAELS+ A  YETVI+ L S+GW+GP
Sbjct  1    MDFGILPPEINSARMYSGPGSSPLLTVASAWSGLAAELSATANDYETVISGLQSQGWVGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            +S AMA ++ PYVAW+ A AA  EQ+A++AR AA+A+EAAFAATVPPP IAANRA L  L
Sbjct  61   SSEAMANSIWPYVAWLRATAAATEQSASKARIAASAYEAAFAATVPPPQIAANRAELTGL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNV GQN++AIAAAEAQYGEMW+QD+A MYAYA S A+A+++TPF +PPQ  NPTA  
Sbjct  121  ISTNVVGQNSAAIAAAEAQYGEMWSQDAATMYAYAASCATATSLTPFVSPPQTTNPTAAA  180

Query  181  TQAAAVAT----AAGTAQSTLTEMITGLPNALQSLTSPL---LQSSNGPLSWLWQILFGT  233
            TQA  ++       GTAQSTL+ +I+ +P  LQ+LTSPL     S+ GP           
Sbjct  181  TQAGTLSRAAATTTGTAQSTLSRLISEVPGVLQALTSPLASAASSTAGP-----------  229

Query  234  PNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAG  293
                  I   L    P+A+FFY+T GLP+F  G+ + F  +AKT G IG AA A  A   
Sbjct  230  ------IERFLEWYAPFANFFYDTLGLPFFGAGITSFFAATAKTAGAIGPAAAAPAATVA  283

Query  294  DAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAA  353
                        +G GPV+A L  A++VGKLSVP  W G  P +    A+      +   
Sbjct  284  ATGAAE-----AVGAGPVSASLAQASTVGKLSVPHTWEGATPATSPTTASKFISDVIEPE  338

Query  354  PEAAPGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
               A G+++GG+P+   G G AGAGPRYG R TVM  PP AG
Sbjct  339  SVEAGGNVIGGVPMPGPGKGSAGAGPRYGVRLTVMPHPPSAG  380


>gi|118616629|ref|YP_904961.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118568739|gb|ABL03490.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=380

 Score =  295 bits (754),  Expect = 1e-77, Method: Compositional matrix adjust.
 Identities = 212/402 (53%), Positives = 265/402 (66%), Gaps = 31/402 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDF  LPPE+NS RMY+GPGS+P++  ASAW+GLAAELS+ A  YETVI+ L S+GW+GP
Sbjct  1    MDFRILPPEINSARMYSGPGSSPLLTVASAWSGLAAELSATANDYETVISGLQSQGWVGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            +S AMA ++ PYVAW+ A AA  EQ+A++AR AA+A+EAAFAATVPPP IAANRA L  L
Sbjct  61   SSEAMANSIWPYVAWLRATAAATEQSASKARIAASAYEAAFAATVPPPQIAANRAELTGL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ISTNV GQN++AIAAAEAQYGEMW+QD+A MYAYA S A+A++VTPF +PPQ  +PTA  
Sbjct  121  ISTNVVGQNSAAIAAAEAQYGEMWSQDAATMYAYAASCATATSVTPFVSPPQTTSPTAAA  180

Query  181  TQ----AAAVATAAGTAQSTLTEMITGLPNALQSLTSPL---LQSSNGPLSWLWQILFGT  233
            TQ    A A AT AGTAQSTL+ +I+ +P  LQ+LTSPL     S+ GP           
Sbjct  181  TQAGTLARAAATTAGTAQSTLSRLISEVPGVLQALTSPLASAASSTAGP-----------  229

Query  234  PNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAG  293
                  I   L    P+A+FFY+T GLP+F  G+ + F  +AKT G IG AA A  A   
Sbjct  230  ------IERFLEWYAPFANFFYDTLGLPFFGAGITSLFAATAKTAGAIGPAAAAPAATVA  283

Query  294  DAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAA  353
                        +G GPV+A L  A++VGKLSVP  W G  P +    A+      +   
Sbjct  284  ATGAAE-----AVGAGPVSASLAQASTVGKLSVPHTWEGATPATSPTTASKFISDVIEPE  338

Query  354  PEAAPGSLLGGLPL--AGAGGAGAGPRYGFRPTVMARPPFAG  393
               A G+++GG+P+   G G AGAGPRYG R TVM  PP AG
Sbjct  339  SVEAGGNVIGGVPMPGPGEGSAGAGPRYGVRLTVMPHPPSAG  380


>gi|342861308|ref|ZP_08717956.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131208|gb|EGT84489.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=410

 Score =  293 bits (749),  Expect = 5e-77, Method: Compositional matrix adjust.
 Identities = 216/421 (52%), Positives = 267/421 (64%), Gaps = 40/421 (9%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS+ +  AASAW+ LAAEL+SAA  YE V+T LSSE W G 
Sbjct  2    VDYGAFPPEFNSARIYSGPGSSSLATAASAWSSLAAELNSAALSYEKVVTSLSSEEWTGA  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MA+A  P+V WM++ AAQAE+AATQA +AA+A+E A +++VPPPLIA+NR    +L
Sbjct  62   ASAEMAQAAEPFVEWMTSTAAQAEEAATQAHSAASAYETALSSSVPPPLIASNRTQATEL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             + NV GQNT  IA  EAQYGE WAQD+AAMY YAG S+SA+ V+ F   PQ+ NP  + 
Sbjct  122  HAKNVLGQNTPLIAQLEAQYGEYWAQDAAAMYRYAGQSSSATKVSQFRKAPQVTNPAGKA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNAL-----------------QSLTSPLLQSSNGPL  223
            TQ+AAV  A      T T   +  P AL                    +S   +SS  P+
Sbjct  182  TQSAAVTNA------TTTSPASNTPKALAAASSGTSGGSSGSAAAGGASSAATKSSTDPM  235

Query  224  SWLWQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGS  283
            S  W +L G  +FP+++ +L+    P+A  FYNTEGLPYFS GM N+F Q AK++G IG 
Sbjct  236  SEAWFLLTGQSSFPSNLGSLVNGYSPFAGLFYNTEGLPYFSTGMANSFTQIAKSVGAIGG  295

Query  284  AAPAAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGA  342
            AAPA   A          LGG        A LG A SV GKLSVP  WSG        GA
Sbjct  296  AAPAVAKALPGLGGLGGMLGGGAAAAHPVAALGGATSVGGKLSVPITWSG------ASGA  349

Query  343  AP-----LPVSTVSAAPEAA--PGSLLGGLPLA---GAGGAGAGPRYGFRPTVMARPPFA  392
            AP     +PVS+VSAAPEAA  PG+LLGG+PL+     G   AGP+YGFRPTVMARPPFA
Sbjct  350  APAVGHAVPVSSVSAAPEAAGEPGNLLGGMPLSGAGAGGHGVAGPKYGFRPTVMARPPFA  409

Query  393  G  393
            G
Sbjct  410  G  410


>gi|240171969|ref|ZP_04750628.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=396

 Score =  291 bits (745),  Expect = 1e-76, Method: Compositional matrix adjust.
 Identities = 224/412 (55%), Positives = 279/412 (68%), Gaps = 36/412 (8%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DFG LPPEV S+RMY+GPGSAPM+AAASAW+GLAAEL++ A  YET++ +L SE W+GP
Sbjct  2    IDFGVLPPEVTSIRMYSGPGSAPMLAAASAWSGLAAELTATADDYETIVARLQSEDWIGP  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            A+ +MA AV PYVAWM A AAQAEQ ATQAR   AA+EAA AA VPPPL+A NRA +  L
Sbjct  62   AATSMAGAVQPYVAWMRATAAQAEQTATQARMLVAAYEAAVAAVVPPPLVAGNRAQVALL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            +STNVFGQNTS +A  EA+YG+MW QD+ AMY YA +SA+AS +TPF++P Q  +P+A  
Sbjct  122  VSTNVFGQNTSRVALLEAEYGDMWTQDATAMYVYAAASANASRLTPFTSPTQTTSPSASA  181

Query  181  TQAAAVATAAGTA----QSTLTEMITGLPNALQSLTSPL--LQSSNG----PLSW-LWQI  229
             Q AAVA AAGTA    Q+ L+++++  PNAL  L +PL  L +S G    P +W +W  
Sbjct  182  WQGAAVAKAAGTAAGGIQNLLSKLVSQAPNALLDLATPLSSLLASAGAAPTPPTWVVW--  239

Query  230  LFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAV  289
                      +   L  + P    +YN  GLPYF IG+ N+   +A+ +G IG   P   
Sbjct  240  ----------LEDFLNLIAPLTGTWYNVTGLPYFGIGITNSLASTARAVGAIG---PEVG  286

Query  290  AAAGDAAKGLPGLGGMLG-GGPVAAGLGNAASVGKLSVPPVWS--GPLPG-SVTPGAAPL  345
            AAA  A        G LG G P+AAG+GNA +VGKLSVPP WS  GP+P  SV   +APL
Sbjct  287  AAAASAGGAAADAAGTLGRGAPIAAGMGNAPAVGKLSVPPGWSATGPVPVPSVGSVSAPL  346

Query  346  PVSTVSAAPEAAPGS--LLGGLPLAGAG--GAGAGPRYGFRPTVMARPPFAG  393
             VS + A PEAA  S  +LGG+PLAG G   AG+ PRYGFRP VM RPPFAG
Sbjct  347  -VSNI-ALPEAASESSNMLGGMPLAGPGVNAAGSAPRYGFRPKVMVRPPFAG  396


>gi|212596789|gb|ACJ35606.1| PPE45 [Mycobacterium intracellulare ATCC 13950]
Length=391

 Score =  285 bits (728),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 214/406 (53%), Positives = 265/406 (66%), Gaps = 29/406 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DFGALPPE++S RMY+GPGSA M+AAA AWN LAAEL SAA  Y+ +ITQL SE W+GP
Sbjct  2    LDFGALPPEIHSERMYSGPGSASMMAAAWAWNLLAAELDSAANDYDRIITQLVSEEWMGP  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MAEA  PYVAWM   A QAEQAA  ARAAA A+EAAFAATVPPPLI ANRA L+Q 
Sbjct  62   ASAQMAEAAKPYVAWMRTTAMQAEQAAVSARAAAGAYEAAFAATVPPPLIEANRAQLVQA  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            +STNV GQNT  I   E QY EMWAQD+ AMY YAG +A  + VTPF+ P +  NP  + 
Sbjct  122  VSTNVLGQNTPLIVQLETQYAEMWAQDATAMYGYAGQAAPVTQVTPFTRPAETTNPAGEA  181

Query  181  TQAAAVATAAGT---AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFP  237
             QAA+VA AAGT   A+S  +++++ +P  LQ+L+SP   ++N  L  +  +L   P F 
Sbjct  182  MQAASVAQAAGTSAGAESAQSQLLSSVPPTLQALSSP--AAANTELPPITDVLEQNPVF-  238

Query  238  TSISALLTDL-QPYASFFYNTEGLPYFSIGMGNNFIQSAKTLG------LIGSAAPAAVA  290
                    D+   YAS   NT  + Y   GM  +F+  +K L         G+ A A++ 
Sbjct  239  --------DMWAEYASPAQNTLAMMYRVTGMSTHFLSLSKGLAPAAKAASEGAKAAASLP  290

Query  291  AAGDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTV  350
            A G + +GL G     GGG ++A L +AA VG LSVPP W+     +V  GA+ +PVS  
Sbjct  291  AVGASLRGLTG-----GGGAISATLASAAPVGGLSVPPAWTSAAGPAVASGASSIPVSRF  345

Query  351  SAAPEAA-PGSLLGGLPLA--GAGGAGAGPRYGFRPTVMARPPFAG  393
               PE + PG+LLGG+PLA  G G  GAGPRYG RPTVMARPPFAG
Sbjct  346  ITTPETSGPGNLLGGMPLAGVGGGSTGAGPRYGIRPTVMARPPFAG  391


>gi|183982678|ref|YP_001850969.1| PPE family protein, PPE26 [Mycobacterium marinum M]
 gi|183176004|gb|ACC41114.1| PPE family protein, PPE26 [Mycobacterium marinum M]
Length=408

 Score =  284 bits (727),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 219/408 (54%), Positives = 260/408 (64%), Gaps = 25/408 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MD+G LPPEV S  MYAGPGS+ MVAAASAWN LAAEL+S A GY TVITQLSSE W+GP
Sbjct  3    MDYGMLPPEVTSALMYAGPGSSSMVAAASAWNALAAELNSTAQGYLTVITQLSSEEWMGP  62

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MA+AV PY+ WMS  A QAE AATQA++AAAAFE AFAA VPPPLIA NRA L Q 
Sbjct  63   ASATMAQAVEPYMTWMSVTAGQAEHAATQAQSAAAAFETAFAAVVPPPLIATNRAELTQA  122

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            + TN+FG N   IA  EAQY EMWAQD++AMY YA SSA A+ +  F+  P IANP A  
Sbjct  123  LQTNMFGLNNGVIAQLEAQYAEMWAQDASAMYNYAASSALATKIESFTEAPTIANPAAST  182

Query  181  TQ--------AAAVATAAGTAQSTLTEMITGL-----PNALQSLTSPLLQSSNGPLSWLW  227
            TQ        A + A+   T QS L+++ + L     P+  QS  S  L +SN  L+ +W
Sbjct  183  TQGAAVSAAQATSAASTQSTVQSFLSQITSQLGQLASPSGTQSFVSQ-LGASNPILTEIW  241

Query  228  QILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPA  287
             +L G    P ++   +     YASFFYNTEGLPYFS+GMGN  +Q AKTLGLI   A A
Sbjct  242  FLLTGQTVLPNNLGTFMQGYSNYASFFYNTEGLPYFSVGMGNFGVQMAKTLGLITQPAAA  301

Query  288  AVAAAGDA-AKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPL-  345
            A AA       G         G  VAAGLG+ A VG L+VP  W G    SV     P  
Sbjct  302  AAAALPKVPGLGGALGAIGSAGSQVAAGLGSGAHVGHLAVPASWPG---ASVAEAVRPTV  358

Query  346  -PVSTVSAAPEAAPGSLLGGLPLAGAG---GAGAGPRYGFRPTVMARP  389
              VS    +PEAA  +++GG+P+   G   G G+GPRYGF+PTVMARP
Sbjct  359  QAVSEPITSPEAA--NVIGGMPVGATGAGRGVGSGPRYGFKPTVMARP  404


>gi|158667960|gb|ABW76444.1| PPE family protein [Mycobacterium avium subsp. avium]
Length=396

 Score =  278 bits (712),  Expect = 8e-73, Method: Compositional matrix adjust.
 Identities = 218/402 (55%), Positives = 268/402 (67%), Gaps = 16/402 (3%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS  +V+AASAW+ LAAEL+SAA  YE V+T LSSE WLG 
Sbjct  2    LDYGAFPPEFNSARIYSGPGSGSLVSAASAWSALAAELNSAALSYEQVVTSLSSEEWLGT  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MA+AV PY+AWM++AAAQAE+AATQARAAAAA+EAA +++VPPPL+A+NR     L
Sbjct  62   ASAMMAQAVEPYIAWMTSAAAQAEEAATQARAAAAAYEAALSSSVPPPLVASNRMQSKLL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+ AMY+YAG S+SA+  TPF  PP+I N +   
Sbjct  122  QATNVLGQNTPLIAQLEAQYGEYWAQDAGAMYSYAGQSSSATKQTPFKEPPKITNESGTA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSI  240
             Q AAV  A   + +T T  I      LQ++ +P    +N P +          +  +  
Sbjct  182  NQTAAVTNATSNSTATDTSKI------LQTMAAPGSSGTNQPTAGTTPTATAPSSGGSGS  235

Query  241  SA---LLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGDAAK  297
             +   L++   P+AS FYNTEGLPYFSIGMGNNF+Q +K+LGLIGSAAPAA  A      
Sbjct  236  GSVSDLVSAYNPFASLFYNTEGLPYFSIGMGNNFVQISKSLGLIGSAAPAAAKALPALGG  295

Query  298  GLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEA  356
                LGG        A LG+AAS+ GKLSVP  WSG    +   G A +PVST+SAAPEA
Sbjct  296  LGGMLGGGAAAAHPVAALGSAASIGGKLSVPVAWSGAPAAAPALGHA-VPVSTISAAPEA  354

Query  357  A--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            A  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  355  AGGPGNLLGGMPLAGAGAGGHGVAGPKYGFRPTVMARPPFAG  396


>gi|118618470|ref|YP_906802.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570580|gb|ABL05331.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=406

 Score =  277 bits (708),  Expect = 3e-72, Method: Compositional matrix adjust.
 Identities = 216/408 (53%), Positives = 259/408 (64%), Gaps = 25/408 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MD+G LPPEV S  MYAGPGS+ MVAAASAWN LAAEL+S A GY TVITQLSSE W+GP
Sbjct  1    MDYGMLPPEVTSALMYAGPGSSSMVAAASAWNALAAELNSTAQGYLTVITQLSSEEWMGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA MA+AV P++ WMS  A QAE AATQA++AAAAFE AFAA VPPPLIA N A L Q 
Sbjct  61   ASATMAQAVEPFMTWMSVTAGQAEHAATQAQSAAAAFETAFAAVVPPPLIATNLAELTQA  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            + TN+FG N   IA  EAQY EMWAQD++AMY YA SSA A+ +  F+  P IA+P A  
Sbjct  121  LQTNMFGLNNGVIAQLEAQYAEMWAQDASAMYNYAASSALATKIESFTEAPTIASPAAST  180

Query  181  TQ--------AAAVATAAGTAQSTLTEMITGL-----PNALQSLTSPLLQSSNGPLSWLW  227
            TQ        A + A+   T QS L+++ + L     P+  QS  S  L +SN  L+ +W
Sbjct  181  TQGAAVSAAQATSAASTQSTVQSFLSQITSQLGQLASPSGTQSFVSQ-LGASNPILTEIW  239

Query  228  QILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPA  287
             +L G    P ++   +     YASFFYNTEGLPYFS+GMGN  +Q AKTLGLI   A A
Sbjct  240  FLLTGQTVLPNNLGTFMQGYSNYASFFYNTEGLPYFSVGMGNFGVQMAKTLGLITQPAAA  299

Query  288  AVAAAGDA-AKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPL-  345
            A AA       G         G  VAAGLG+ A VG L+VP  W G    SV     P  
Sbjct  300  AAAALPKVPGLGGALGAIGSAGSQVAAGLGSGAHVGHLAVPASWPG---ASVAEAVRPTV  356

Query  346  -PVSTVSAAPEAAPGSLLGGLPLAGAG---GAGAGPRYGFRPTVMARP  389
              VS    +PEAA  +++GG+P+   G   G G+GPRYGF+PTVMARP
Sbjct  357  QAVSEPITSPEAA--NVIGGMPVGATGAGRGVGSGPRYGFKPTVMARP  402


>gi|240167786|ref|ZP_04746445.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=380

 Score =  273 bits (699),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 227/403 (57%), Positives = 280/403 (70%), Gaps = 33/403 (8%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPE+NS+R+Y+GPGSAPMVAAASAW+GLAAEL+SAA  Y+TVIT L SEGW+GP
Sbjct  1    MDFGALPPEINSIRLYSGPGSAPMVAAASAWSGLAAELTSAANEYQTVITALHSEGWVGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ++  MA AVAPYVAWM A AA AEQAA +AR AAAA+E AFAA VPPP IAANRA L  L
Sbjct  61   SAVTMAAAVAPYVAWMRATAAAAEQAAGKARLAAAAYETAFAAVVPPPQIAANRAQLSTL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANP----  176
            IS NV GQNT+AIAA E QYG+MWAQD+AAMYAYA +SA+ASAVTPF +PPQ  +P    
Sbjct  121  ISANVVGQNTAAIAATETQYGQMWAQDAAAMYAYAAASATASAVTPFISPPQTTSPAASA  180

Query  177  TAQGTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPL---LQSSNGPLSWLWQILFGT  233
            T      +A ATAAG  QSTL+ +++ LP  L+ L SPL   + ++ GP           
Sbjct  181  TQAAAVTSAAATAAGATQSTLSSLLSELPGVLEGLASPLASAVSATAGP-----------  229

Query  234  PNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAG  293
                  I   L    P+A+F Y+T GLP+F  G+ + F  +AKT+GLIG AA A  AAA 
Sbjct  230  ------IERFLEWWAPFANFLYDTAGLPFFGAGIASFFASTAKTMGLIGPAAAAPEAAAA  283

Query  294  DAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTV-SA  352
             A         ++GGGPV+A L  A+++GKLSVPP W+G  P   TP +  + VS V   
Sbjct  284  AAGAAG-----LVGGGPVSASLAQASTIGKLSVPPTWAGASP-VATPTSTSMFVSDVIEP  337

Query  353  APEAAPGSLLGGLPLAGA--GGAGAGPRYGFRPTVMARPPFAG  393
            A   + G+++GG+P+AG+  G AGAGPRYGFRPTV+ RPP AG
Sbjct  338  ADLGSSGNVVGGMPMAGSSRGSAGAGPRYGFRPTVVTRPPSAG  380


>gi|342861306|ref|ZP_08717954.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131206|gb|EGT84487.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=405

 Score =  270 bits (690),  Expect = 3e-70, Method: Compositional matrix adjust.
 Identities = 220/412 (54%), Positives = 263/412 (64%), Gaps = 27/412 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS   VAAASAW+ LAAEL+SAA  Y+ VIT LSSE W G 
Sbjct  2    VDYGAFPPEFNSARIYSGPGSGSFVAAASAWSALAAELNSAALSYDNVITALSSEEWTGT  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAMA+A  PYV W++  AAQAE+AATQARAAA+A+E A A++VPPPLIAANR    QL
Sbjct  62   ASAAMAQAAEPYVTWLTTTAAQAEEAATQARAAASAYETALASSVPPPLIAANRTQSQQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+ AMY+YAG +ASA+ VT F   P++ N + Q 
Sbjct  122  QATNVLGQNTPLIAQLEAQYGEYWAQDAGAMYSYAGQAASATKVTQFQKAPEVTNQSGQA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSL-------------TSPLLQSSNGPLSWLW  227
             QAAAV  A   + +T T         LQSL              +    S+  PLS +W
Sbjct  182  NQAAAVTNATANSTATNTS------KTLQSLATPASTTTTSATTATTAATSTTDPLSEVW  235

Query  228  QILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPA  287
             +L G  + PT++  L+    P+A  FYNTEGLPYFS GM N F Q AK++G IG AAPA
Sbjct  236  FLLTGQTSLPTNLGTLVNGYSPFAGLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAPA  295

Query  288  AVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPLP  346
               A          LGG        A LG+AASV GKLSVP  WSG  P +   G A +P
Sbjct  296  VAKALPGLGGLGGMLGGGAAAAHPVAALGSAASVGGKLSVPVAWSG-APAAPALGHA-IP  353

Query  347  VSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            VS++SAAPEAA  PG+LL          AG   AGP+YGFRPTVMARPPFAG
Sbjct  354  VSSISAAPEAAGGPGNLLGGMPLAGAGAAGHGVAGPKYGFRPTVMARPPFAG  405


>gi|254821314|ref|ZP_05226315.1| PPE family protein [Mycobacterium intracellulare ATCC 13950]
Length=376

 Score =  259 bits (663),  Expect = 5e-67, Method: Compositional matrix adjust.
 Identities = 204/392 (53%), Positives = 252/392 (65%), Gaps = 29/392 (7%)

Query  15   MYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGPASAAMAEAVAPYVA  74
            MY+GPGSA M+AAA AWN LAAEL SAA  Y+ +ITQL SE W+GPASA MAEA  PYVA
Sbjct  1    MYSGPGSASMMAAAWAWNLLAAELDSAANDYDRIITQLVSEEWMGPASAQMAEAAKPYVA  60

Query  75   WMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQLISTNVFGQNTSAIA  134
            WM   A QAEQAA  ARAAA A+EAAFAATVPPPLI ANRA L+Q +STNV GQNT  I 
Sbjct  61   WMRTTAMQAEQAAVSARAAAGAYEAAFAATVPPPLIEANRAQLVQAVSTNVLGQNTPLIV  120

Query  135  AAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQGTQAAAVATAAGT--  192
              E QY EMWAQD+ AMY YAG +A  + VTPF+ P +  NP  +  QAA+VA AAGT  
Sbjct  121  QLETQYAEMWAQDATAMYGYAGQAAPVTQVTPFTRPAETTNPAGEAMQAASVAQAAGTSA  180

Query  193  -AQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTSISALLTDL-QPY  250
             A+S  +++++ +P  LQ+L+SP   ++N  L  +  +L   P F         D+   Y
Sbjct  181  GAESAQSQLLSSVPPTLQALSSP--AAANTELPPITDVLEQNPVF---------DMWAEY  229

Query  251  ASFFYNTEGLPYFSIGMGNNFIQSAKTLG------LIGSAAPAAVAAAGDAAKGLPGLGG  304
            AS   NT  + Y   GM  +F+  +K L         G+ A A++ A G + +GL G   
Sbjct  230  ASPAQNTLAMMYRVTGMSTHFLSLSKGLAPAAKAASEGAKAAASLPAVGASLRGLTG---  286

Query  305  MLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTVSAAPEAA-PGSLLG  363
              GGG ++A L +AA VG LSVPP W+     +V  GA+ +PVS     PE + PG+LLG
Sbjct  287  --GGGAISATLASAAPVGGLSVPPAWTSAAGPAVASGASSIPVSRFITTPETSGPGNLLG  344

Query  364  GLPLA--GAGGAGAGPRYGFRPTVMARPPFAG  393
            G+PLA  G G  GAGPRYG RPTVMARPPFAG
Sbjct  345  GMPLAGVGGGSTGAGPRYGIRPTVMARPPFAG  376


>gi|118466367|ref|YP_882110.1| PPE family protein [Mycobacterium avium 104]
 gi|118167654|gb|ABK68551.1| ppe family protein [Mycobacterium avium 104]
Length=405

 Score =  252 bits (644),  Expect = 7e-65, Method: Compositional matrix adjust.
 Identities = 231/413 (56%), Positives = 272/413 (66%), Gaps = 28/413 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MD+GA PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  1    MDYGAFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAA+EAA AA+VPPPLIAANR  + QL
Sbjct  61   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAYEAALAASVPPPLIAANRMQVSQL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  121  QATNVLGQNTPLIAQLEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQA  180

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  181  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  234

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            W +L G  + PT++  L+    P+A  FYNTEGLPYFS GM N F Q AK++G IG AAP
Sbjct  235  WFLLTGQTSLPTNLGTLVNGYSPFAGLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  294

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPL  345
            AA  A          LGG        A LG A S+ GKLSVP  WSG  P +   G A +
Sbjct  295  AAAKALPGLGGLGGMLGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APATPALGHA-I  352

Query  346  PVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  353  PVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  405


>gi|158667958|gb|ABW76443.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis]
Length=406

 Score =  251 bits (641),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 231/413 (56%), Positives = 272/413 (66%), Gaps = 28/413 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  2    LDYGAFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAA+EAA AA+VPPPLIAANR  + QL
Sbjct  62   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAYEAALAASVPPPLIAANRMQVSQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  122  QATNVLGQNTPLIAQLEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  182  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  235

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            W +L G    PTS+ + +    P+AS FYNTEGLPYFS GM N F Q AK++G IG AAP
Sbjct  236  WFLLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  295

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPL  345
            AA  A          LGG        A LG A S+ GKLSVP  WSG  P +   G A +
Sbjct  296  AAAKALPGLGGLGGMLGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APAAPALGHA-I  353

Query  346  PVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  354  PVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  406


>gi|118464959|ref|YP_882112.1| PPE family protein [Mycobacterium avium 104]
 gi|118166246|gb|ABK67143.1| ppe family protein [Mycobacterium avium 104]
Length=407

 Score =  251 bits (641),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 230/413 (56%), Positives = 271/413 (66%), Gaps = 28/413 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+G  PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  3    LDYGTFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  62

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAA+EAA AA+VPPPLIAANR  + QL
Sbjct  63   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAYEAALAASVPPPLIAANRMQVSQL  122

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  123  QATNVLGQNTPLIAQLEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQA  182

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  183  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  236

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            W +L G    PTS+ + +    P+AS FYNTEGLPYFS GM N F Q AK++G IG AAP
Sbjct  237  WFLLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  296

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPL  345
            AA  A          LGG        A LG A S+ GKLSVP  WSG  P +   G A +
Sbjct  297  AAAKALPGLGGLGGMLGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APATPALGHA-I  354

Query  346  PVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  355  PVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  407


>gi|212596061|gb|ACJ35548.1| PPE23 [Mycobacterium avium subsp. avium]
Length=406

 Score =  251 bits (640),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 230/413 (56%), Positives = 271/413 (66%), Gaps = 28/413 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+G  PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  2    LDYGTFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAA+EAA AA+VPPPLIAANR  + QL
Sbjct  62   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAYEAALAASVPPPLIAANRMQVSQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  122  QATNVLGQNTPLIAQLEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  182  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  235

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            W +L G    PTS+ + +    P+AS FYNTEGLPYFS GM N F Q AK++G IG AAP
Sbjct  236  WFLLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  295

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPL  345
            AA  A          LGG        A LG A S+ GKLSVP  WSG  P +   G A +
Sbjct  296  AAAKALPGLGGLGGMLGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APATPALGHA-I  353

Query  346  PVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  354  PVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  406


>gi|158667962|gb|ABW76445.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis]
 gi|336457653|gb|EGO36657.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=406

 Score =  249 bits (635),  Expect = 7e-64, Method: Compositional matrix adjust.
 Identities = 230/413 (56%), Positives = 272/413 (66%), Gaps = 28/413 (6%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  2    LDYGAFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAA+EAA AA+VPPPLIAAN+  + QL
Sbjct  62   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAYEAALAASVPPPLIAANQMQVSQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  122  QATNVLGQNTPLIAQLEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQA  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  182  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  235

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAP  286
            W +L G    PTS+ + +    P+AS FYNTEGLPYFS GM N F Q AK++G IG AAP
Sbjct  236  WFLLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  295

Query  287  AAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAPL  345
            AA  A          LGG        A LG A S+ GKLSVP  WSG  P +   G A +
Sbjct  296  AAAKALPGLGGLGGMLGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APAAPALGHA-I  353

Query  346  PVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  354  PVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  406


>gi|342861307|ref|ZP_08717955.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131207|gb|EGT84488.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=417

 Score =  248 bits (632),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 199/420 (48%), Positives = 253/420 (61%), Gaps = 30/420 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPE+NS RMYAGPGS PM+AAA+AW+GL AELSSAA+GY +VI++L+   W+GP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPMMAAAAAWDGLGAELSSAASGYTSVISELTHAPWVGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS++M  AV PYV+W+S  AAQAE+ A QARAAAAAFEAAFA TVPPP+IAANR  L  L
Sbjct  61   ASSSMLSAVTPYVSWLSVLAAQAEETAGQARAAAAAFEAAFAMTVPPPVIAANRVLLANL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++TN  GQNT AIAA EAQY EMWAQD+AAMY YAGSSA AS + P ++PP    P A  
Sbjct  121  VATNFLGQNTPAIAATEAQYMEMWAQDAAAMYGYAGSSAVASELPPLTSPPNTTTPEADS  180

Query  181  TQAAAVATA----AGTAQSTLTEMIT------GLPNALQSLTSPLLQSSNGPLSWLWQIL  230
             QAAAVA A    AG    T +++ T      G   A+   ++    +  GP +WL  ++
Sbjct  181  DQAAAVAKAVAEPAGNTAQTTSQLATPQALSAGATQAVTQASTTTTATQPGPFTWLQNLI  240

Query  231  --FGTPNFPT---SISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAA  285
              F T   PT   + + L T +  Y +    T GL YFS G+ + +   A+ L       
Sbjct  241  NGFLTSGLPTPTNNYAGLNTGM--YGTLLKQTTGLAYFSTGITSFWSSIAQQLTFGPGGT  298

Query  286  PAAVAAA-----GDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTP  340
             A    A       A+ GL  LGG+   G V+AG+G A  VG LSVP  W+  L  SV+P
Sbjct  299  TAGAGGAWFPTPQFASLGLGNLGGVGHVGAVSAGVGQAGRVGMLSVPQHWA-TLTSSVSP  357

Query  341  GA---APLPVSTVSAAPEAAPGSLLGGLPLAGAGGAGAG----PRYGFRPTVMARPPFAG  393
             A      P+   +    +    LL G+P+   G  GA      +YGFR +V+ RPP AG
Sbjct  358  AALSEEATPIQAAAGGANSPANGLLRGMPVGSIGRRGAAAGYVNKYGFRYSVLTRPPSAG  417


>gi|41407604|ref|NP_960440.1| hypothetical protein MAP1506 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395957|gb|AAS03823.1| hypothetical protein MAP_1506 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=407

 Score =  245 bits (625),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 228/414 (56%), Positives = 271/414 (66%), Gaps = 29/414 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +D+GA PPE NS R+Y+GPGS  +VAAASAW+ LAAEL++AA  Y+ V+T L+SE WLG 
Sbjct  2    LDYGAFPPEFNSARIYSGPGSGSLVAAASAWSSLAAELNAAALSYDKVVTALASEEWLGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA AVAPYV WMS  AAQAE+AA+QARAAAAAFEAA AA+VPPP+IAANR  + QL
Sbjct  62   ASASMASAVAPYVGWMSTTAAQAEEAASQARAAAAAFEAALAASVPPPVIAANRMQVSQL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
             +TNV GQNT  IA  EAQYGE WAQD+AAMY+YAG SASAS VTPF   PQ+ NP+ Q 
Sbjct  122  QATNVLGQNTPLIAQFEAQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAPQVTNPSGQV  181

Query  181  TQAAAVATAAGTAQSTLTEMITGLPNALQSLTSP--------------LLQSSNGPLSWL  226
             Q+AAV+TA   + ST T        ALQSL  P                 +S  PLS +
Sbjct  182  AQSAAVSTATANSTSTNTT------KALQSLAQPASSSTTATKAATTAASTTSTDPLSEI  235

Query  227  WQILFGTPNFPTSISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTL-GLIGSAA  285
            W +L G    PTS+ + +    P+AS FYNTEGLPYFS GM N F Q AK++  + G+A 
Sbjct  236  WFLLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMANTFTQIAKSVGAIGGAAP  295

Query  286  PAAVAAAGDAAKGLPGLGGMLGGGPVAAGLGNAASV-GKLSVPPVWSGPLPGSVTPGAAP  344
             AA A  G    G    GG        A LG A S+ GKLSVP  WSG  P +   G A 
Sbjct  296  AAAKALPGLGGLGGMLGGGGAAAAHPVAALGGAGSIGGKLSVPVAWSG-APAAPALGHA-  353

Query  345  LPVSTVSAAPEAA--PGSLL---GGLPLAGAGGAGAGPRYGFRPTVMARPPFAG  393
            +PVS++SAAPEAA  PG+LL           G   AGP+YGFRPTVMARPPFAG
Sbjct  354  IPVSSISAAPEAAGGPGNLLGGMPLAGAGAGGHGAAGPKYGFRPTVMARPPFAG  407


>gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478]
Length=401

 Score =  239 bits (610),  Expect = 5e-61, Method: Compositional matrix adjust.
 Identities = 195/406 (49%), Positives = 243/406 (60%), Gaps = 22/406 (5%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DF  LPPE+NS RMY+GPGS PM+AAASAW  LAAEL + A  Y +V+  L+ E W GP
Sbjct  5    LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP  64

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA A APYVAW++  A QAEQ A QA AAA A+EAAF ATVPPP+IAANRA LM L
Sbjct  65   ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL  124

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            I+TN+ GQNT AIAA EAQY EMWAQD+ AMY YAGSSA+A+ ++PF  P Q  NP+   
Sbjct  125  IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA  184

Query  181  TQAAAV----ATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
             QAAAV    A +AG   STL+ +I+ +P+ALQ L+ P   +S   L  +W +L G+   
Sbjct  185  AQAAAVTEASANSAGNQSSTLSGLISMVPSALQGLSGP---NSTSWLQVIWDLLTGS--G  239

Query  237  PTSISALLTDLQPYASFFYNTEGLPYFSIG------MGNNFIQSAKTLGLIGSAAPAAVA  290
            P     L     P A+ +        F  G      M +    +        ++A AA  
Sbjct  240  PAWWQTLWNVWGPNANVWNTITSTGLFVPGSTFAPFMASVLAGAVAADAAQDASAAAAGV  299

Query  291  AAGDAAKGLPGLGGMLGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVSTV  350
             +G AA  L   G +  G  V+AGLGNA  VGKLSVPP W+   P     G+A      V
Sbjct  300  GSGLAAGPLASTGSV--GSAVSAGLGNAGIVGKLSVPPAWTAAAPLHSPLGSALGGTPMV  357

Query  351  SAAPEAAPGSLLGGLPLAGAGGAGAG---PRYGFRPTVMARPPFAG  393
            +  P  A G  + G+P     G   G   P+YGFRPT +ARPP AG
Sbjct  358  APPPAVAAG--MPGMPFGNMAGQPFGRAVPQYGFRPTFVARPPAAG  401


>gi|254821012|ref|ZP_05226013.1| PPE family protein, PPE31 [Mycobacterium intracellulare ATCC 
13950]
 gi|212596828|gb|ACJ35609.1| PPE48 [Mycobacterium intracellulare ATCC 13950]
Length=389

 Score =  238 bits (607),  Expect = 1e-60, Method: Compositional matrix adjust.
 Identities = 207/406 (51%), Positives = 252/406 (63%), Gaps = 32/406 (7%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DF  LPPE+NS RMYAGPGS PM+ AASAWNGLAAEL SAA  Y + ++ L+SE W GP
Sbjct  3    VDFATLPPEINSARMYAGPGSGPMLVAASAWNGLAAELRSAALSYGSALSSLTSEEWHGP  62

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASAAM  A  PYVAWMS  A QAEQAATQA AAAAA+EAAFAATVPPP IAANRA L  L
Sbjct  63   ASAAMVAAATPYVAWMSTTATQAEQAATQAEAAAAAYEAAFAATVPPPAIAANRAQLATL  122

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPT---  177
            I+TNV GQNT AIAA EAQYGEMWAQD+A MY YAGSSA+A+ +  F+ P Q  +     
Sbjct  123  IATNVLGQNTPAIAATEAQYGEMWAQDAATMYGYAGSSAAATRLPMFTDPTQTTSQDGQA  182

Query  178  -AQGTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNF  236
                  A A  T+AG  Q+T++++ T +PNALQ+L+SP  +SS G  S L  IL    NF
Sbjct  183  RQAAAVAQATGTSAGNQQATVSQLNTAVPNALQTLSSP-TESSTGSTSGLSSILDPNSNF  241

Query  237  PTSISAL--LTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLGLIGSAAPAAVAAAGD  294
              +I++   L   Q   +   +T       IG       S   L  + S AP A    G 
Sbjct  242  WNTITSTGALDPAQVVQTVTSSTL------IG------ASTSALNDLASGAPVAT-GIGT  288

Query  295  AAKGLPGLGGM-LGGGPVAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLPVS---TV  350
            +A+ L GL G+   G  V+AGLG A+ VG LSVPP W+ P      P A+PLP +   T 
Sbjct  289  SAQSLSGLAGVGNAGASVSAGLGRASLVGPLSVPPSWAPP-----APVASPLPSALGGTP  343

Query  351  SAAPEAAPGSLLGGLPLAGAGGAGAG---PRYGFRPTVMARPPFAG  393
              AP  A  + + G+P +  G  G G   P+YGFRP  + RPP AG
Sbjct  344  MVAPPPAMAAGMPGMPFSPMGNHGLGRAVPQYGFRPNFVVRPPAAG  389


>gi|289446957|ref|ZP_06436701.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289419915|gb|EFD17116.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=396

 Score =  238 bits (606),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 178/416 (43%), Positives = 235/416 (57%), Gaps = 44/416 (10%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DFGALPPE+NS RMYAGPGSA +VAAA  W+ +A++L SAA+ +++V+  L++  W+G 
Sbjct  2    VDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ++  MA A +PYVAWMS  A QAE  A Q R AAAA+E A+  TVPPP+IA NRA LM L
Sbjct  62   SAGLMAAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYRLTVPPPVIAENRAELMIL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAY-AGSSASASAVTPFSTPPQIANPTAQ  179
            I+TN+ GQNT AIA  EA+YGEMWAQD+AAM+ Y A ++ +  A+ PF   P I NP   
Sbjct  122  IATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGGL  181

Query  180  GTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTS  239
              QA AV  A  TA +   +++  +P ALQ L  P           +W            
Sbjct  182  LEQAVAVEEAIDTAAA--NQLMNNVPQALQQLAQPTKS--------IWPF--------DQ  223

Query  240  ISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTL-GLIGSAAPAAVAAAGDAAKG  298
            +S L   + P+ S   N   +    + M N+ +  A TL  ++   APAA  A   AA+ 
Sbjct  224  LSELWKAISPHLSPLSNIVSMLNNHVSMTNSGVSMASTLHSMLKGLAPAAAQAVETAAQN  283

Query  299  LPGLGGMLGGGP--------------VAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAP  344
              G+  M   G               VAA LG AASVG LSVPP W+     +VTP A  
Sbjct  284  --GVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPPAWAAA-NQAVTPAARA  340

Query  345  LPVSTVSAAPEAAPGSLLGGLPL-------AGAGGAGAGPRYGFRPTVMARPPFAG  393
            LP++++++A + APG +LGGLPL        G GG     R   R  VM R P AG
Sbjct  341  LPLTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG  396


>gi|183981478|ref|YP_001849769.1| PPE family protein [Mycobacterium marinum M]
 gi|183174804|gb|ACC39914.1| PPE family protein [Mycobacterium marinum M]
Length=427

 Score =  237 bits (605),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 181/382 (48%), Positives = 237/382 (63%), Gaps = 42/382 (10%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPE+NS RMY GPGS PM+AAA  W+ LAAEL + A GY + +  L+   W GP
Sbjct  1    MDFGALPPEINSGRMYVGPGSGPMLAAAVVWDELAAELYATAAGYRSTLDGLTGGSWRGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ASA+MA A APYVAWM+A AAQAE A +QA+ AA+A+E AFAATVPPP+IAANRA LM L
Sbjct  61   ASASMAAAAAPYVAWMTATAAQAELAGSQAKVAASAYETAFAATVPPPVIAANRALLMGL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            + TN+FGQNT AIAA EA Y EMWAQD+AAMYAYAGSSA+A+ VTPF+ PPQI +P+   
Sbjct  121  VFTNIFGQNTPAIAATEAHYAEMWAQDAAAMYAYAGSSATATQVTPFTEPPQITSPSGAV  180

Query  181  TQAAAVATAAGTAQST-----LTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPN  235
            +QAAAV  AA  + S+     L+ +I  +PNALQ +      +S  P +     + G P+
Sbjct  181  SQAAAVTEAATASASSDITAQLSPLIAVVPNALQGMA-----TSGNPAA----AIAGLPD  231

Query  236  FPTSISALLTDLQPYASFF------YNTEGL------PYFSIGMGNNFIQS--------A  275
                 + ++TDLQ + +        +  +GL      P+ + G    F Q+        +
Sbjct  232  VALP-AGIITDLQNFTTILDTLDGPFTIQGLTGVPGGPFLAFGQVYAFSQNMVGAQAFFS  290

Query  276  KTLGLIGSAAPAAVAAAGDAAKGLPGLGGMLGGGPVAAG-LGNAASVGKLSVPPVWSGPL  334
                +IG  AP     AG+A  G  G+ G    G  A+G +G+AA VG +SVP  W+   
Sbjct  291  PAEPVIGGLAP----LAGEANLGAAGVVGGPSVGGQASGAMGHAALVGNMSVPQGWTQEA  346

Query  335  PGSVTPGAAPLPVSTVSAAPEA  356
            P ++    + LP S V+AAP A
Sbjct  347  P-AIRVFVSELPTS-VTAAPAA  366


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  236 bits (602),  Expect = 5e-60, Method: Compositional matrix adjust.
 Identities = 195/427 (46%), Positives = 249/427 (59%), Gaps = 39/427 (9%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDF ALPPE+NS+RMY+GPGSAPM+AA +AW+GLAAEL S A  YETVI  L+ +GWLGP
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            AS +M  AV PY+AWM+    QAEQ A QA AAA AFEAAFA TVPP  +AANR  L  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAYAGSSASASAVTPFSTPPQIANPTAQG  180
            ++TN+ GQNT AIAA EA YGEMWAQD+AAMY YA  SA+AS +T F+ P Q  +P+   
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  181  TQAAAVATAAGT-----AQSTLTEMITGLPNALQSLTSPLLQS------SNGPLSWLWQI  229
            +Q+AAV  A G+      Q+ L ++++ +P +LQ L SP   S       +G L+ L   
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  230  LFGTPNFPTSISALLTDLQPYASFFYNTEGL--PYFSIGMGNNFIQSAKTLGLIGSAA--  285
            L G    P  +    + +  + S  Y +  +  P     M +    +A  LG   SAA  
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMAD---INAVALGAQESAAVP  297

Query  286  --------PAAVAAAGDAA-KGLPGLG----GMLGGGPVAAGLGNAASVGKLSVPPVWSG  332
                    P+ + AA  A+ + LP LG      LG G ++AG+  A  VG++SVP  W  
Sbjct  298  PMGSGEGNPSWIPAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRMSVPQSWGV  357

Query  333  PLPGSVTPGAAPLPVSTVSAA--PEAAPGSLLGGLPLAGAG----GAGAGPRYGFRPTVM  386
                +   GAA       S A  PEAA G  + G+P   AG      G  PRYGFRPT+M
Sbjct  358  ATAVANHAGAAAPGGGWTSTAVVPEAAVG--MPGIPGMPAGIYGHNLGNAPRYGFRPTIM  415

Query  387  ARPPFAG  393
             RPP AG
Sbjct  416  GRPPAAG  422


>gi|306784092|ref|ZP_07422414.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|306788459|ref|ZP_07426781.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|306792785|ref|ZP_07431087.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
 gi|306797185|ref|ZP_07435487.1| PPE family protein [Mycobacterium tuberculosis SUMu006]
 gi|308331160|gb|EFP20011.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308334942|gb|EFP23793.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308338747|gb|EFP27598.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308342446|gb|EFP31297.1| PPE family protein [Mycobacterium tuberculosis SUMu006]
Length=396

 Score =  236 bits (601),  Expect = 6e-60, Method: Compositional matrix adjust.
 Identities = 175/414 (43%), Positives = 231/414 (56%), Gaps = 40/414 (9%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            +DFGALPPE+NS RMYAGPGSA +VAAA  W+ +A++L SAA+ +++V+  L++  W+G 
Sbjct  2    VDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGS  61

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ++  M  A +PYVAWMS  A QAE  A Q R AAAA+E A+  TVPPP+IA NRA LM L
Sbjct  62   SAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMIL  121

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAY-AGSSASASAVTPFSTPPQIANPTAQ  179
            I+TN+ GQNT AIA  EA+YGEMWAQD+AAM+ Y A ++ +  A+ PF   P I NP   
Sbjct  122  IATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGGL  181

Query  180  GTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTS  239
              QA AV  A  TA +   +++  +P ALQ L  P           +W            
Sbjct  182  LEQAVAVEEAIDTAAA--NQLMNNVPQALQQLAQPTKS--------IWPF--------DQ  223

Query  240  ISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLG--LIGSAAPAAVAAAGDAAK  297
            +S L   + P+ S   N   +    + M N+ +  A TL   L G A  AA A    A  
Sbjct  224  LSELWKAISPHLSPLSNIVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQN  283

Query  298  GLPGLGGMLGGGP-----------VAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLP  346
            G+  +  +                VAA LG AASVG LSVPP W+     +VTP A  LP
Sbjct  284  GVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPPAWAAA-NQAVTPAARALP  342

Query  347  VSTVSAAPEAAPGSLLGGLPL-------AGAGGAGAGPRYGFRPTVMARPPFAG  393
            ++++++A + APG +LGGLPL        G GG     R   R  VM R P AG
Sbjct  343  LTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG  396


>gi|308231818|ref|ZP_07413879.2| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308215968|gb|EFO75367.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
Length=395

 Score =  235 bits (599),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 175/414 (43%), Positives = 230/414 (56%), Gaps = 40/414 (9%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPE+NS RMYAGPGSA +VAAA  W+ +A++L SAA+ +++V+  L++  W+G 
Sbjct  1    MDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGS  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ++  M  A +PYVAWMS  A QAE  A Q R AAAA+E A+  TVPPP+IA NRA LM L
Sbjct  61   SAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMIL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAY-AGSSASASAVTPFSTPPQIANPTAQ  179
            I+TN+ GQNT AIA  EA+YGEMWAQD+AAM+ Y A ++ +  A+ PF   P I NP   
Sbjct  121  IATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGGL  180

Query  180  GTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTS  239
              QA AV  A  TA +   +++  +P ALQ L  P           +W            
Sbjct  181  LEQAVAVEEAIDTAAA--NQLMNNVPQALQQLAQPTKS--------IWPF--------DQ  222

Query  240  ISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLG--LIGSAAPAAVAAAGDAAK  297
            +S L   + P+ S   N   +    + M N+ +  A TL   L G A  AA A    A  
Sbjct  223  LSELWKAISPHLSPLSNIVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQN  282

Query  298  GLPGLGGMLGGGP-----------VAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLP  346
            G+  +  +                VAA LG AASVG LSVP  W+     +VTP A  LP
Sbjct  283  GVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPQAWAAA-NQAVTPAARALP  341

Query  347  VSTVSAAPEAAPGSLLGGLPL-------AGAGGAGAGPRYGFRPTVMARPPFAG  393
            ++++++A + APG +LGGLPL        G GG     R   R  VM R P AG
Sbjct  342  LTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG  395


>gi|289554847|ref|ZP_06444057.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289439479|gb|EFD21972.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=395

 Score =  235 bits (599),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 175/414 (43%), Positives = 230/414 (56%), Gaps = 40/414 (9%)

Query  1    MDFGALPPEVNSVRMYAGPGSAPMVAAASAWNGLAAELSSAATGYETVITQLSSEGWLGP  60
            MDFGALPPE+NS RMYAGPGSA +VAAA  W+ +A++L SAA+ +++V+  L++  W+G 
Sbjct  1    MDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIGS  60

Query  61   ASAAMAEAVAPYVAWMSAAAAQAEQAATQARAAAAAFEAAFAATVPPPLIAANRASLMQL  120
            ++  M  A +PYVAWMS  A QAE  A Q R AAAA+E A+  TVPPP+IA NRA LM L
Sbjct  61   SAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMIL  120

Query  121  ISTNVFGQNTSAIAAAEAQYGEMWAQDSAAMYAY-AGSSASASAVTPFSTPPQIANPTAQ  179
            I+TN+ GQNT AIA  EA+YGEMWAQD+AAM+ Y A ++ +  A+ PF   P I NP   
Sbjct  121  IATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAATAATATEALLPFEDAPLITNPGGL  180

Query  180  GTQAAAVATAAGTAQSTLTEMITGLPNALQSLTSPLLQSSNGPLSWLWQILFGTPNFPTS  239
              QA AV  A  TA +   +++  +P ALQ L  P           +W            
Sbjct  181  LEQAVAVEEAIDTAAA--NQLMNNVPQALQQLAQPTKS--------IWPF--------DQ  222

Query  240  ISALLTDLQPYASFFYNTEGLPYFSIGMGNNFIQSAKTLG--LIGSAAPAAVAAAGDAAK  297
            +S L   + P+ S   N   +    + M N+ +  A TL   L G A  AA A    A  
Sbjct  223  LSELWKAISPHLSPLSNIVSMLNNHVSMTNSGVSMASTLHSMLKGFAPAAAQAVETAAQN  282

Query  298  GLPGLGGMLGGGP-----------VAAGLGNAASVGKLSVPPVWSGPLPGSVTPGAAPLP  346
            G+  +  +                VAA LG AASVG LSVP  W+     +VTP A  LP
Sbjct  283  GVRAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPQAWAAA-NQAVTPAARALP  341

Query  347  VSTVSAAPEAAPGSLLGGLPL-------AGAGGAGAGPRYGFRPTVMARPPFAG  393
            ++++++A + APG +LGGLPL        G GG     R   R  VM R P AG
Sbjct  342  LTSLTSAAQTAPGHMLGGLPLGQLTNSGGGFGGVSNALRMPPRAYVMPRVPAAG  395



Lambda     K      H
   0.312    0.126    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 767373824232


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40