BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1801

Length=423
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15841271|ref|NP_336308.1|  PPE family protein [Mycobacterium t...   809    0.0   
gi|339631855|ref|YP_004723497.1|  PPE family protein [Mycobacteri...   808    0.0   
gi|339294738|gb|AEJ46849.1|  PPE family protein [Mycobacterium tu...   807    0.0   
gi|289574478|ref|ZP_06454705.1|  PPE family protein [Mycobacteriu...   806    0.0   
gi|289447416|ref|ZP_06437160.1|  PPE family protein [Mycobacteriu...   803    0.0   
gi|340626811|ref|YP_004745263.1|  PPE family protein [Mycobacteri...   802    0.0   
gi|313658681|ref|ZP_07815561.1|  PPE family protein [Mycobacteriu...   778    0.0   
gi|167967221|ref|ZP_02549498.1|  PPE family protein [Mycobacteriu...   758    0.0   
gi|289745767|ref|ZP_06505145.1|  PPE family protein [Mycobacteriu...   655    0.0   
gi|289750372|ref|ZP_06509750.1|  PPE family protein [Mycobacteriu...   646    0.0   
gi|289761951|ref|ZP_06521329.1|  PPE family protein [Mycobacteriu...   626    2e-177
gi|289757904|ref|ZP_06517282.1|  PPE family protein [Mycobacteriu...   594    7e-168
gi|254550809|ref|ZP_05141256.1|  PPE family protein [Mycobacteriu...   553    1e-155
gi|183981478|ref|YP_001849769.1|  PPE family protein [Mycobacteri...   317    2e-84 
gi|240171262|ref|ZP_04749921.1|  PPE family protein [Mycobacteriu...   297    2e-78 
gi|57116921|ref|YP_177844.1|  PPE family protein [Mycobacterium t...   289    5e-76 
gi|31792997|ref|NP_855490.1|  PPE family protein [Mycobacterium b...   289    7e-76 
gi|167967397|ref|ZP_02549674.1|  PPE family protein [Mycobacteriu...   288    1e-75 
gi|294996719|ref|ZP_06802410.1|  PPE family protein [Mycobacteriu...   287    2e-75 
gi|240172862|ref|ZP_04751521.1|  PPE family protein [Mycobacteriu...   286    5e-75 
gi|308372058|ref|ZP_07427232.2|  putative PPE family protein [Myc...   279    7e-73 
gi|183982691|ref|YP_001850982.1|  PPE family protein, PPE32 [Myco...   272    6e-71 
gi|296170356|ref|ZP_06851947.1|  PPE family protein [Mycobacteriu...   271    2e-70 
gi|118618457|ref|YP_906789.1|  PPE family protein [Mycobacterium ...   269    8e-70 
gi|307084423|ref|ZP_07493536.1|  putative PPE family protein [Myc...   268    2e-69 
gi|212596761|gb|ACJ35604.1|  PPE43 [Mycobacterium intracellulare ...   263    3e-68 
gi|254550816|ref|ZP_05141263.1|  PPE family protein [Mycobacteriu...   260    3e-67 
gi|15841278|ref|NP_336315.1|  PPE family protein [Mycobacterium t...   252    8e-65 
gi|296164791|ref|ZP_06847351.1|  PPE family protein [Mycobacteriu...   251    1e-64 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   246    7e-63 
gi|118618459|ref|YP_906791.1|  PPE family protein [Mycobacterium ...   243    3e-62 
gi|342859619|ref|ZP_08716272.1|  PPE family protein [Mycobacteriu...   242    1e-61 
gi|289574372|ref|ZP_06454599.1|  PPE family protein [Mycobacteriu...   240    3e-61 
gi|118466613|ref|YP_881225.1|  PPE family protein [Mycobacterium ...   236    5e-60 
gi|240169037|ref|ZP_04747696.1|  PPE family protein [Mycobacteriu...   236    6e-60 
gi|333991947|ref|YP_004524561.1|  PPE family protein [Mycobacteri...   232    9e-59 
gi|118466467|ref|YP_882538.1|  PPE family protein [Mycobacterium ...   232    1e-58 
gi|333990650|ref|YP_004523264.1|  PPE family protein [Mycobacteri...   231    2e-58 
gi|296170357|ref|ZP_06851948.1|  PPE family protein [Mycobacteriu...   230    3e-58 
gi|307079711|ref|ZP_07488881.1|  PPE family protein [Mycobacteriu...   229    6e-58 
gi|336458159|gb|EGO37142.1|  PPE-repeat containing protein [Mycob...   229    7e-58 
gi|340626711|ref|YP_004745163.1|  PPE family protein [Mycobacteri...   228    1e-57 
gi|31792891|ref|NP_855384.1|  PPE family protein [Mycobacterium b...   228    1e-57 
gi|15841163|ref|NP_336200.1|  PPE family protein [Mycobacterium t...   227    3e-57 
gi|57116898|ref|YP_177827.1|  PPE family protein [Mycobacterium t...   227    3e-57 
gi|167969175|ref|ZP_02551452.1|  PPE family protein [Mycobacteriu...   227    4e-57 
gi|57116922|ref|YP_177845.1|  PPE family protein [Mycobacterium t...   227    4e-57 
gi|289745858|ref|ZP_06505236.1|  PPE family protein [Mycobacteriu...   226    5e-57 
gi|296167733|ref|ZP_06849950.1|  PPE family protein [Mycobacteriu...   226    7e-57 
gi|336457980|gb|EGO36967.1|  PPE-repeat containing protein [Mycob...   226    8e-57 


>gi|15841271|ref|NP_336308.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31792989|ref|NP_855482.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57116916|ref|YP_177840.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 57 more sequence titles
 Length=423

 Score =  809 bits (2089),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/423 (100%), Positives = 423/423 (100%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|339631855|ref|YP_004723497.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339331211|emb|CCC26893.1| PPE family protein [Mycobacterium africanum GM041182]
Length=423

 Score =  808 bits (2087),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/423 (99%), Positives = 423/423 (100%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQD+AAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|339294738|gb|AEJ46849.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
Length=423

 Score =  807 bits (2085),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/423 (99%), Positives = 422/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLL IQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLSIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|289574478|ref|ZP_06454705.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538909|gb|EFD43487.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=423

 Score =  806 bits (2082),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 421/423 (99%), Positives = 422/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQD+AAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGG VTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGEVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|289447416|ref|ZP_06437160.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420374|gb|EFD17575.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=423

 Score =  803 bits (2073),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 421/423 (99%), Positives = 421/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLM LI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMGLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDG GALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGPGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|340626811|ref|YP_004745263.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005001|emb|CCC44149.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=423

 Score =  802 bits (2072),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/423 (99%), Positives = 420/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELA AQARLA+AAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAAAQARLAVAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNH QLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHSQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQT ATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTVATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP+
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPM  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA
Sbjct  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|313658681|ref|ZP_07815561.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=409

 Score =  778 bits (2009),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/409 (100%), Positives = 409/409 (100%), Gaps = 0/409 (0%)

Query  15   MYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAW  74
            MYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAW
Sbjct  1    MYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAW  60

Query  75   MSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMM  134
            MSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMM
Sbjct  61   MSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMM  120

Query  135  TEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAG  194
            TEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAG
Sbjct  121  TEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAG  180

Query  195  GNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGV  254
            GNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGV
Sbjct  181  GNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGV  240

Query  255  LPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGG  314
            LPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGG
Sbjct  241  LPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGG  300

Query  315  GSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMA  374
            GSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMA
Sbjct  301  GSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMA  360

Query  375  LSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD  423
            LSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD
Sbjct  361  LSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD  409


>gi|167967221|ref|ZP_02549498.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=400

 Score =  758 bits (1957),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 400/400 (100%), Positives = 400/400 (100%), Gaps = 0/400 (0%)

Query  24   MLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAE  83
            MLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAE
Sbjct  1    MLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAE  60

Query  84   LAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMW  143
            LAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMW
Sbjct  61   LAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMW  120

Query  144  AQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQ  203
            AQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQ
Sbjct  121  AQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQ  180

Query  204  LLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYL  263
            LLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYL
Sbjct  181  LLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYL  240

Query  264  LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGR  323
            LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGR
Sbjct  241  LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGR  300

Query  324  AGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAA  383
            AGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAA
Sbjct  301  AGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAA  360

Query  384  AGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD  423
            AGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD
Sbjct  361  AGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD  400


>gi|289745767|ref|ZP_06505145.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289686295|gb|EFD53783.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=418

 Score =  655 bits (1690),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 338/338 (100%), Positives = 338/338 (100%), Gaps = 0/338 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTV  338
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTV
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTV  338


>gi|289750372|ref|ZP_06509750.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289690959|gb|EFD58388.1| PPE family protein [Mycobacterium tuberculosis T92]
Length=333

 Score =  646 bits (1667),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 333/333 (100%), Positives = 333/333 (100%), Gaps = 0/333 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVP  333
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVP
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVP  333


>gi|289761951|ref|ZP_06521329.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|289709457|gb|EFD73473.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
Length=423

 Score =  626 bits (1615),  Expect = 2e-177, Method: Compositional matrix adjust.
 Identities = 375/423 (89%), Positives = 377/423 (90%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPI  360
            ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRL     
Sbjct  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLGRRAD  360

Query  361  AATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
                  G +       GL           P     +           DLATEANIFVIPA
Sbjct  361  CGHRRRGCVARWHGAVGLGWPRCRRFYRPPHRQRRSTRRRCRCRCRRDLATEANIFVIPA  420

Query  421  MDD  423
            MDD
Sbjct  421  MDD  423


>gi|289757904|ref|ZP_06517282.1| PPE family protein [Mycobacterium tuberculosis T85]
 gi|289713468|gb|EFD77480.1| PPE family protein [Mycobacterium tuberculosis T85]
Length=305

 Score =  594 bits (1532),  Expect = 7e-168, Method: Compositional matrix adjust.
 Identities = 305/305 (100%), Positives = 305/305 (100%), Gaps = 0/305 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300

Query  301  ALHTP  305
            ALHTP
Sbjct  301  ALHTP  305


>gi|254550809|ref|ZP_05141256.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
Length=284

 Score =  553 bits (1426),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 284/284 (100%), Positives = 284/284 (100%), Gaps = 0/284 (0%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI
Sbjct  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA
Sbjct  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF
Sbjct  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGK  284
            LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGK
Sbjct  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGK  284


>gi|183981478|ref|YP_001849769.1| PPE family protein [Mycobacterium marinum M]
 gi|183174804|gb|ACC39914.1| PPE family protein [Mycobacterium marinum M]
Length=427

 Score =  317 bits (813),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 223/436 (52%), Positives = 266/436 (62%), Gaps = 22/436 (5%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTG-AWSGP  59
            MDFG LPPEINSGRMY GPG GPMLAAA  WD LA EL+ATAAGY S L  LTG +W GP
Sbjct  1    MDFGALPPEINSGRMYVGPGSGPMLAAAVVWDELAAELYATAAGYRSTLDGLTGGSWRGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +S SMA+AAAPYVAWM+ATA  AELAG+QA++A +AYE AFAATVPPPVIAANRA LM L
Sbjct  61   ASASMAAAAAPYVAWMTATAAQAELAGSQAKVAASAYETAFAATVPPPVIAANRALLMGL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            + TNIFGQNTPAI  TEA Y EMWAQDAAAMY YAGSSATA+++T FTEPPQ T+     
Sbjct  121  VFTNIFGQNTPAIAATEAHYAEMWAQDAAAMYAYAGSSATATQVTPFTEPPQITSPSGAV  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLA-----------LPTASQSASATP  228
            +Q++AV + A  +A  ++ +    L++ VP ALQG+A           LP  +  A    
Sbjct  181  SQAAAVTEAATASASSDITAQLSPLIAVVPNALQGMATSGNPAAAIAGLPDVALPAGI--  238

Query  229  QWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGK  288
              +TDL N +T L   + GP+T  G+    G P+L   Q    +QN  G  A       +
Sbjct  239  --ITDLQNFTTIL-DTLDGPFTIQGLTGVPGGPFLAFGQVYAFSQNMVGAQAFFSP--AE  293

Query  289  PITGALAPLA-EFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPA  347
            P+ G LAPLA E  L    +      GG  S  +G A LVG +SVPQGWT  AP I    
Sbjct  294  PVIGGLAPLAGEANLGAAGVVGGPSVGGQASGAMGHAALVGNMSVPQGWTQEAPAIRVFV  353

Query  348  AALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVE  407
            + L  T + AAP A   G  A+   MALS LAGRA         G   A        A  
Sbjct  354  SELP-TSVTAAPAATLAGESAVFNQMALSSLAGRALGTGAFGSGGGGGASKAIGGVVAEA  412

Query  408  DLATEANIFVIPAMDD  423
            D A  A I VIPA++D
Sbjct  413  DPAA-ATIIVIPAIED  427


>gi|240171262|ref|ZP_04749921.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=415

 Score =  297 bits (761),  Expect = 2e-78, Method: Compositional matrix adjust.
 Identities = 223/428 (53%), Positives = 270/428 (64%), Gaps = 26/428 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            +DFG LPPEINSGRMY GPG GPMLAAA AWD LA  LH+TAA Y+S +S LT  W GP+
Sbjct  3    IDFGALPPEINSGRMYIGPGSGPMLAAAAAWDSLAAGLHSTAASYSSVISGLTAGWQGPA  62

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            S +MA+AAAPY AW++ATA  AE    QAR+A  A+E AFAATVPPP + ANRAQLM LI
Sbjct  63   SITMAAAAAPYTAWINATAAQAEQTATQARVAAVAFETAFAATVPPPAVTANRAQLMALI  122

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN FGQNTPAIM T+A+Y+EMWAQDAAAMYGYAGSSATAS++T F+EPPQ  N      
Sbjct  123  ATNFFGQNTPAIMGTQAEYIEMWAQDAAAMYGYAGSSATASQVTPFSEPPQIANPAGTEW  182

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDL---GNL  237
            Q++AVA+  +  AG    S  PQL+S VP +LQ LA P +S + +A            +L
Sbjct  183  QAAAVARATSAVAGMQTMS-LPQLMSGVPSSLQSLAAPGSSTALAAAADPTAPASLASSL  241

Query  238  STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
            +T +   +TGP +   +   +GVPYLLGIQS L+ QN   V+             A    
Sbjct  242  NTII-STITGPSSALSLFTIAGVPYLLGIQSYLLPQNVANVANA-----------ASKVS  289

Query  298  AEFALHTPILGSEGLGGG---SVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATR  354
            A  A     +G    GGG   + SAG+GRAGLVG LSVPQGW ++AP +   AA      
Sbjct  290  AASASSGGWVGVGSAGGGLSSAASAGMGRAGLVGGLSVPQGWAMSAPAVKPVAAVFAENG  349

Query  355  LAAAP-IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLAT-E  412
            L  AP  AAT G G+L   MALSGLAGRA       P G  AA + GA   A    A+  
Sbjct  350  LTGAPAAAATQGEGSLFSNMALSGLAGRAMV-----PTGGTAARSSGATGGATAGEASGP  404

Query  413  ANIFVIPA  420
             NIF++PA
Sbjct  405  VNIFIVPA  412


>gi|57116921|ref|YP_177844.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661614|ref|YP_001283137.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148823021|ref|YP_001287775.1| PPE family protein [Mycobacterium tuberculosis F11]
 9 more sequence titles
 Length=409

 Score =  289 bits (740),  Expect = 5e-76, Method: Compositional matrix adjust.
 Identities = 229/421 (55%), Positives = 273/421 (65%), Gaps = 14/421 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            MDFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  181  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  238

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE  299
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  239  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  294

Query  300  FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP  359
              L    +G     GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T  A A 
Sbjct  295  --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPA-  351

Query  360  IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP  419
              A +  GAL G MALS LAGRA AG+    + S A  A  A  +  ED+A+   I VIP
Sbjct  352  -LAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP  407

Query  420  A  420
            A
Sbjct  408  A  408


>gi|31792997|ref|NP_855490.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121637710|ref|YP_977933.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224990194|ref|YP_002644881.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 29 more sequence titles
 Length=409

 Score =  289 bits (739),  Expect = 7e-76, Method: Compositional matrix adjust.
 Identities = 230/426 (54%), Positives = 274/426 (65%), Gaps = 24/426 (5%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            MDFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  181  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  238

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLA-  298
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  239  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  294

Query  299  ----EFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATR  354
                  A  TP+       GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T 
Sbjct  295  LRGGYIADITPL-------GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTG  347

Query  355  LAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEAN  414
             A A   A +  GAL G MALS LAGRA AG+    + S A  A  A  +  ED+A+   
Sbjct  348  AAPA--LAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTT  402

Query  415  IFVIPA  420
            I VIPA
Sbjct  403  IIVIPA  408


>gi|167967397|ref|ZP_02549674.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|253799148|ref|YP_003032149.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254231990|ref|ZP_04925317.1| PPE family protein [Mycobacterium tuberculosis C]
 24 more sequence titles
 Length=410

 Score =  288 bits (737),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 228/421 (55%), Positives = 273/421 (65%), Gaps = 14/421 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  2    LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  62   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  122  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  182  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  239

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE  299
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  240  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  295

Query  300  FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP  359
              L    +G     GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T  A A 
Sbjct  296  --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPA-  352

Query  360  IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP  419
              A +  GAL G MALS LAGRA AG+    + S A  A  A  +  ED+A+   I VIP
Sbjct  353  -LAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP  408

Query  420  A  420
            A
Sbjct  409  A  409


>gi|294996719|ref|ZP_06802410.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|13377907|gb|AAK20893.1| Rv1808-like protein [Mycobacterium microti]
 gi|13377909|gb|AAK20894.1| Rv1808-like protein [Mycobacterium microti]
 gi|339294744|gb|AEJ46855.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
 gi|339298372|gb|AEJ50482.1| PPE family protein [Mycobacterium tuberculosis CCDC5180]
Length=410

 Score =  287 bits (735),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 229/426 (54%), Positives = 274/426 (65%), Gaps = 24/426 (5%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  2    LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  62   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  122  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  182  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  239

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLA-  298
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  240  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  295

Query  299  ----EFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATR  354
                  A  TP+       GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T 
Sbjct  296  LRGGYIADITPL-------GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTG  348

Query  355  LAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEAN  414
             A A   A +  GAL G MALS LAGRA AG+    + S A  A  A  +  ED+A+   
Sbjct  349  AAPA--LAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTT  403

Query  415  IFVIPA  420
            I VIPA
Sbjct  404  IIVIPA  409


>gi|240172862|ref|ZP_04751521.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=431

 Score =  286 bits (732),  Expect = 5e-75, Method: Compositional matrix adjust.
 Identities = 236/436 (55%), Positives = 286/436 (66%), Gaps = 19/436 (4%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALT-GAWSGP  59
            +DFG LPPEINSGRMY GPG GPMLAAA AW  LA EL + AA Y S + +LT G+W+GP
Sbjct  2    IDFGALPPEINSGRMYVGPGAGPMLAAAAAWQELAAELQSMAASYRSIVESLTVGSWTGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APY+AW+++T   AE A AQA  A AAYE AFAATVPPPVIAANRA LM L
Sbjct  62   SSIAMAAAVAPYLAWINSTGAQAEQAAAQAAAAAAAYETAFAATVPPPVIAANRALLMAL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            IATNIFGQNTPAI  TEA+Y+EMWAQDAAAMY YAGSSATA+++T FTEPP TTN     
Sbjct  122  IATNIFGQNTPAIAATEAEYLEMWAQDAAAMYAYAGSSATAAQLTPFTEPPATTNPSAAA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLA----LPTASQS-------ASATP  228
            AQS+AVA  A TAA  ++ +   QL+++VP ALQ LA    LPTA+ S         A P
Sbjct  182  AQSAAVAPAAGTAAASDITTQLSQLIASVPNALQSLASTTSLPTAAPSLPGSIFPLPALP  241

Query  229  QWV-TDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGG  287
             W+ TD+ N +  +  A+ GPY+  G+    G P+L   Q     QN QG+ A       
Sbjct  242  PWLATDIDNWNIIM-AALNGPYSLQGLAAIPGGPFLSFGQVYAYAQNAQGLQAFFAP--S  298

Query  288  KPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPA  347
            KPITGALAP+A+         S G GGG V+  +GRA LVG ++VPQGWT AAP +    
Sbjct  299  KPITGALAPIADSLGANLTSSSAGSGGGPVTGAMGRAALVGSMAVPQGWTQAAPAM-RLV  357

Query  348  AALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVE  407
            ++L  T LAAAP AA  G   + G MALS LAGRA A +T    GS  A ++G   A  +
Sbjct  358  SSLLPTNLAAAPAAAFSGEAGVFGQMALSSLAGRALAATTFGSAGSGTASSLGGVVAGAD  417

Query  408  DLATEANIFVIPAMDD  423
              A  A I VIPA+D+
Sbjct  418  PAA--ATIIVIPALDE  431


>gi|308372058|ref|ZP_07427232.2| putative PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308334577|gb|EFP23428.1| putative PPE family protein [Mycobacterium tuberculosis SUMu004]
Length=399

 Score =  279 bits (713),  Expect = 7e-73, Method: Compositional matrix adjust.
 Identities = 216/387 (56%), Positives = 257/387 (67%), Gaps = 11/387 (2%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  2    LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  62   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  122  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  182  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  239

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE  299
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  240  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  295

Query  300  FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP  359
              L    +G     GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T  A A 
Sbjct  296  --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPA-  352

Query  360  IAATDGAGALLGGMALSGLAGRAAAGS  386
              A +  GAL G MALS LAGRA AG+
Sbjct  353  -LAAEAPGALFGEMALSSLAGRALAGT  378


>gi|183982691|ref|YP_001850982.1| PPE family protein, PPE32 [Mycobacterium marinum M]
 gi|183176017|gb|ACC41127.1| PPE family protein, PPE32 [Mycobacterium marinum M]
Length=426

 Score =  272 bits (696),  Expect = 6e-71, Method: Compositional matrix adjust.
 Identities = 228/438 (53%), Positives = 281/438 (65%), Gaps = 28/438 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG  P++AAA AWD LA EL + AA Y S +  LT A W+G 
Sbjct  2    IDFGALPPEINSGRMYVGPGAAPLIAAAAAWDELAAELQSMAASYGSTVQGLTVAPWTGA  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+AAAPYV W++ T V AE A  QA+LA  AYE AFAATVPPPVIAANRA LM L
Sbjct  62   SSITMAAAAAPYVTWINTTGVQAEQAATQAKLAAGAYETAFAATVPPPVIAANRALLMAL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            IATNIFGQNTPAI   EAQY+EMWAQDAAAMY YAG++A AS +T FTEPPQTTN     
Sbjct  122  IATNIFGQNTPAIAAAEAQYLEMWAQDAAAMYAYAGTAAAASALTPFTEPPQTTNPVAGA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSAS------ATPQWV-T  232
            AQS+AVAQ ++TAA  ++ S    L+++VP ALQ LA  +A+ +A+      + P W+ T
Sbjct  182  AQSAAVAQASSTAASSDVVSQLAGLITSVPNALQTLATTSAAPTAASILPEVSLPPWLAT  241

Query  233  DLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITG  292
            +L N +T +   +TGP++  G+    G P+L   Q     QN QG++A       K ITG
Sbjct  242  NLANWNTIM-ATLTGPFSLQGISSIPGGPFLSFGQVYAYVQNAQGLNAFYSP---KAITG  297

Query  293  ALAPLAEFALHTPILGSEGLG------GGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSP  346
             LAPL       P +   G+G        SVS  +GRA LVG +SVPQGWT AAP +   
Sbjct  298  TLAPL------VPEISPGGVGLTSASVSNSVSGTMGRAALVGSMSVPQGWTQAAPAMRLV  351

Query  347  AAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGST-GHPIGSAAAPAVGAAAAA  405
            ++ L +T LAAAP A   G   + G MALS LAGRA   ST G   G A A ++G   A 
Sbjct  352  SSVL-STNLAAAPTAGLPGEAGVFGQMALSSLAGRAMGASTFGSSSGGAVANSLGGVVAE  410

Query  406  VEDLATEANIFVIPAMDD  423
             +  A  A I VIPA+D+
Sbjct  411  ADPAA--ATIIVIPALDE  426


>gi|296170356|ref|ZP_06851947.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895079|gb|EFG74798.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=409

 Score =  271 bits (693),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 210/379 (56%), Positives = 251/379 (67%), Gaps = 14/379 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            +DFG+LPPEINS RMYTGPG GPMLAAA AWD LA +LHATAA  +S +S LT  W GP+
Sbjct  3    IDFGMLPPEINSTRMYTGPGAGPMLAAAAAWDELAAQLHATAASQSSVVSGLTAQWRGPA  62

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            S +MA+AAAPY AWMS  A  AEL   QAR A AAYE AFAATVPP  +AANRA+L+ L+
Sbjct  63   SETMAAAAAPYTAWMSTAAGQAELTAGQARAAAAAYETAFAATVPPVSVAANRARLLALV  122

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN FGQNTPAIM T+A+Y EMWAQDAAAMYGYA SSATA+++T F  PPQTTN      
Sbjct  123  ATNFFGQNTPAIMATQAEYAEMWAQDAAAMYGYAASSATAAQVTPFAPPPQTTNPAGAPE  182

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            Q+++V Q  ATAAG       PQL+SA P+ALQ LA P  + + +A P    D  +L + 
Sbjct  183  QAASVGQATATAAGAQATR-LPQLMSATPQALQSLAAPMQAAAPAAAPAAAADPPSLFSA  241

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEF  300
            L G +TGP +   +    GVPYLLGIQS L  Q G  ++        +  + ALA     
Sbjct  242  LDGFITGPLSPASLFTIPGVPYLLGIQSYLTPQAGANLTR-----ASENYSKALA-----  291

Query  301  ALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAAL-QATRLAAAP  359
                   G   +    VSAG+GRAGLVG LSVPQGW  AAPEI + AA L Q++  AA  
Sbjct  292  --KADAAGVPRMVSAPVSAGVGRAGLVGGLSVPQGWASAAPEIKTIAATLPQSSLSAAPA  349

Query  360  IAATDGAGALLGGMALSGL  378
              A DG G+L+G MALSGL
Sbjct  350  ALAADGQGSLVGNMALSGL  368


>gi|118618457|ref|YP_906789.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570567|gb|ABL05318.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=426

 Score =  269 bits (687),  Expect = 8e-70, Method: Compositional matrix adjust.
 Identities = 227/438 (52%), Positives = 280/438 (64%), Gaps = 28/438 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG  P++AAA AWD LA EL + AA Y S +  LT A W+G 
Sbjct  2    IDFGALPPEINSGRMYVGPGAAPLIAAAAAWDELAAELQSMAASYGSTVQGLTVAPWTGA  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+AAAPYV W++ T V AE A  QA+LA  AYE A AATVPPPVIAANRA LM L
Sbjct  62   SSITMAAAAAPYVTWINTTGVQAEQAATQAKLAAGAYETASAATVPPPVIAANRALLMAL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            IATNIFGQNTPAI   EAQY+EMWAQDAAAMY YAG++A AS +T FTEPPQTTN     
Sbjct  122  IATNIFGQNTPAIAAAEAQYLEMWAQDAAAMYAYAGTAAAASALTPFTEPPQTTNPVAGA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSAS------ATPQWV-T  232
            AQS+AVAQ ++TAA  ++ S    L+++VP ALQ LA  +A+ +A+      + P W+ T
Sbjct  182  AQSAAVAQASSTAASSDVVSQLAGLITSVPNALQTLATTSAAPTAASILPEVSLPPWLAT  241

Query  233  DLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITG  292
            +L N +T +   +TGP++  G+    G P+L   Q     QN QG++A       K ITG
Sbjct  242  NLANWNTIM-ATLTGPFSLQGISSIPGGPFLSFGQVYAYVQNAQGLNAFYSP---KAITG  297

Query  293  ALAPLAEFALHTPILGSEGLG------GGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSP  346
             LAPL       P +   G+G        SVS  +GRA LVG +SVPQGWT AAP +   
Sbjct  298  TLAPL------VPEISPGGVGLTSASVSNSVSGTMGRAALVGSMSVPQGWTQAAPAMRLV  351

Query  347  AAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGST-GHPIGSAAAPAVGAAAAA  405
            ++ L +T LAAAP A   G   + G MALS LAGRA   ST G   G A A ++G   A 
Sbjct  352  SSVL-STNLAAAPTAGLPGEAGVFGQMALSSLAGRAMGASTFGSSSGGAVANSLGGVVAE  410

Query  406  VEDLATEANIFVIPAMDD  423
             +  A  A I VIPA+D+
Sbjct  411  ADPAA--ATIIVIPALDE  426


>gi|307084423|ref|ZP_07493536.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|308365983|gb|EFP54834.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=336

 Score =  268 bits (684),  Expect = 2e-69, Method: Compositional matrix adjust.
 Identities = 195/342 (58%), Positives = 231/342 (68%), Gaps = 9/342 (2%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GP
Sbjct  2    LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+A APYVAW+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L
Sbjct  62   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     
Sbjct  122  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
            AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T
Sbjct  182  AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT  239

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE  299
             L   +TGPY+  G+    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA 
Sbjct  240  ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP  295

Query  300  FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAP  341
              L    +G     GG  + GI RA  VG LSVPQGW  AAP
Sbjct  296  --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAP  335


>gi|212596761|gb|ACJ35604.1| PPE43 [Mycobacterium intracellulare ATCC 13950]
Length=409

 Score =  263 bits (673),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 225/433 (52%), Positives = 274/433 (64%), Gaps = 38/433 (8%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFG++PPE+NSGRMY+GPG GPMLAAA AW+ LA +LHA AA Y S +S LT  W GPS
Sbjct  1    MDFGVMPPEVNSGRMYSGPGAGPMLAAAAAWEALAAQLHAAAASYESVISNLTAGWRGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            S+ MA+AAAPY AWMSATA  AE   +QAR A+ AYEAAF ATVPPPVIAANRAQLM LI
Sbjct  61   SSMMAAAAAPYAAWMSATAAQAEQTASQARAAVVAYEAAFLATVPPPVIAANRAQLMALI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN  GQNTPAIM TEAQY EMWAQDAAAMYGYAG+SA A+++T F  PP++TN      
Sbjct  121  ATNFLGQNTPAIMATEAQYAEMWAQDAAAMYGYAGASAAAAQVTPFAPPPRSTNPAGTAG  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTF  240
            Q++AVAQ    +   N +SA PQL+S+VP++LQ L  P A+           D  +L + 
Sbjct  181  QAAAVAQATGGSVATNTESALPQLMSSVPQSLQTLTTPAAA----------ADPPSLLSA  230

Query  241  LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVS----------ALLGKIGGKPI  290
               A+TGP     +    G PYLLG+++ LV QN   V+          + LG++GG+  
Sbjct  231  FDSALTGPLGPVSLFGIGGSPYLLGVENYLVPQNVANVNSARQRLDRDRSALGRLGGEVN  290

Query  291  TGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAAL  350
            +G           T ++ S    G  +S GIGRAG+VG+LSVP GW  AAPEI S A  +
Sbjct  291  SG-----------TQMVSSPRAAGTGMSPGIGRAGVVGRLSVPPGWAAAAPEIRSVATVI  339

Query  351  QATRLAAAPIA-ATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDL  409
              T  A AP A A +G G+L   MA SGL GRA A + G   GSA A  +GA        
Sbjct  340  PQTAFAGAPSALAAEGEGSLFSSMAASGLVGRAMAATGG---GSARASGIGAGFGRA---  393

Query  410  ATEANIFVIPAMD  422
            AT A I VI A D
Sbjct  394  ATTATIIVINADD  406


>gi|254550816|ref|ZP_05141263.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297634368|ref|ZP_06952148.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|297731355|ref|ZP_06960473.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313658689|ref|ZP_07815569.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=395

 Score =  260 bits (665),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 216/407 (54%), Positives = 260/407 (64%), Gaps = 14/407 (3%)

Query  15   MYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGPSSTSMASAAAPYVA  73
            MY GPG GP+LAAA AWD LA EL++ AA Y S +  LT A W GPSS +MA+A APYVA
Sbjct  1    MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA  60

Query  74   WMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIM  133
            W+S TA  AE AGAQA++A   YE AFAATVPPPVI ANRA LM L+ATNIFGQNTPAI 
Sbjct  61   WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA  120

Query  134  MTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAA  193
             TEA Y EMWAQDAAAMYGYAGSSATAS++  F+EPPQTTN     AQS+ VAQ A  AA
Sbjct  121  ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA  180

Query  194  GGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPG  253
              ++ +   QL+S +P  LQ LA  T + + SA+  W T L +++T L   +TGPY+  G
Sbjct  181  SSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITTILAN-LTGPYSIIG  237

Query  254  VLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLG  313
            +    G  +L   Q + + QN  GV+ALLG    K   GAL+PLA   L    +G     
Sbjct  238  LGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP--LRGGYIGDITPL  292

Query  314  GGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGM  373
            GG  + GI RA  VG LSVPQGW  AAP + + A+ L  T  A A   A +  GAL G M
Sbjct  293  GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPA--LAAEAPGALFGEM  350

Query  374  ALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA  420
            ALS LAGRA AG+    + S A  A  A  +  ED+A+   I VIPA
Sbjct  351  ALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIPA  394


>gi|15841278|ref|NP_336315.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881506|gb|AAK46129.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=386

 Score =  252 bits (644),  Expect = 8e-65, Method: Compositional matrix adjust.
 Identities = 198/383 (52%), Positives = 241/383 (63%), Gaps = 14/383 (3%)

Query  39   HATAAGYASELSALTGA-WSGPSSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYE  97
            ++ AA Y S +  LT A W GPSS +MA+A APYVAW+S TA  AE AGAQA++A   YE
Sbjct  16   YSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYE  75

Query  98   AAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSS  157
             AFAATVPPPVI ANRA LM L+ATNIFGQNTPAI  TEA Y EMWAQDAAAMYGYAGSS
Sbjct  76   TAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSS  135

Query  158  ATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLAL  217
            ATAS++  F+EPPQTTN     AQS+ VAQ A  AA  ++ +   QL+S +P  LQ LA 
Sbjct  136  ATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA-  194

Query  218  PTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQG  277
             T + + SA+  W T L +++T L   +TGPY+  G+    G  +L   Q + + QN  G
Sbjct  195  -TTATATSASAGWDTVLQSITTILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPG  252

Query  278  VSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWT  337
            V+ALLG    K   GAL+PLA   L    +G     GG  + GI RA  VG LSVPQGW 
Sbjct  253  VAALLGP---KAAAGALSPLAP--LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWA  307

Query  338  VAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAP  397
             AAP + + A+ L  T  A A   A +  GAL G MALS LAGRA AG+    + S A  
Sbjct  308  EAAPVMRAVASVLPGTGAAPA--LAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGA  362

Query  398  AVGAAAAAVEDLATEANIFVIPA  420
            A  A  +  ED+A+   I VIPA
Sbjct  363  ARVAGGSVTEDVASTTTIIVIPA  385


>gi|296164791|ref|ZP_06847351.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295899845|gb|EFG79291.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=420

 Score =  251 bits (642),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 223/425 (53%), Positives = 265/425 (63%), Gaps = 8/425 (1%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            +DFG LPPEINSGRMY G G GP+LAAA AWD LA EL  T A Y S +  L TG W+GP
Sbjct  2    LDFGALPPEINSGRMYVGAGSGPLLAAAAAWDELAAELQVTGASYNSIIETLATGPWTGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            S+ +MA+AAAPYVAW++AT   AE AGAQA++A  AYEAAFAATVPPPVIAANRA L  L
Sbjct  62   SAIAMAAAAAPYVAWINATGAQAEAAGAQAKVAAGAYEAAFAATVPPPVIAANRALLATL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            IATNI GQNTPAI  TEAQYMEMWAQDAAAMYGYA SSATAS++T F EPPQTTN     
Sbjct  122  IATNILGQNTPAIAATEAQYMEMWAQDAAAMYGYAASSATASQLTPFAEPPQTTNTDSTV  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST  239
             Q+SA+ Q+ A A+  N  S   QL + +  A+Q L   T + + S        + N +T
Sbjct  182  MQASAMTQSTAQAS-SNTVSHLSQLSATMQPAMQTLNAGTNAGTTSTGLTVPPIVQNWNT  240

Query  240  FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE  299
            F   AVTG Y+        G P+L   Q+    QNGQ  +A L   G K ITGALAPL  
Sbjct  241  FW-SAVTGVYSPQSWSTIPGGPFLSFGQAYAWGQNGQSAAAYLS--GPKAITGALAPLTS  297

Query  300  FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP  359
             A     + S  + GG VS  +G+A LVG +SVPQGWT AAP + + A  + A   AA  
Sbjct  298  GASAVKPMLSSAV-GGQVSGSLGKAALVGNMSVPQGWTEAAPAVRTIAQVIPANLAAAP-  355

Query  360  IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAV-EDLATEANIFVI  418
             A   G   +   M LS L GRA A S  H +G+ AA A G+    V E     A I VI
Sbjct  356  AATLAGEEGMFSQMGLSSLLGRAVASSATHSVGATAAKAAGSLGGVVAEADPAAATIIVI  415

Query  419  PAMDD  423
            PA++D
Sbjct  416  PALED  420


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  246 bits (627),  Expect = 7e-63, Method: Compositional matrix adjust.
 Identities = 174/360 (49%), Positives = 216/360 (60%), Gaps = 23/360 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTG-AWSGP  59
            MDF  LPPEINS RMY+GPG  PMLAA TAWDGLA EL +TAA Y + ++ LTG  W GP
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +S SM +A  PY+AWM+ T + AE    QA  A  A+EAAFA TVPP  +AANR QL  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ GQNTPAI  TEA Y EMWAQDAAAMYGYA  SA AS +T FT+P QTT+   L 
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATP--QWVTDLGNL  237
            +QS+AV Q   +  G   Q+  PQL+SAVP +LQGLA P A+    A P    +  L N 
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  238  --------------STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSV-LVTQNGQGVSALL  282
                          S+ + G V+  Y  P V+ P+    +  I +V L  Q    V  + 
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADINAVALGAQESAAVPPMG  300

Query  283  GKIGGKPITGALAPLAEFALHTPILGSE---GLGGGSVSAGIGRAGLVGKLSVPQGWTVA  339
               G      A +P +  +L  P+LG E    LG G +SAG+ +A LVG++SVPQ W VA
Sbjct  301  SGEGNPSWIPAASPASPESL--PVLGEETAATLGTGGISAGMNQAELVGRMSVPQSWGVA  358


>gi|118618459|ref|YP_906791.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570569|gb|ABL05320.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=450

 Score =  243 bits (621),  Expect = 3e-62, Method: Compositional matrix adjust.
 Identities = 171/357 (48%), Positives = 213/357 (60%), Gaps = 23/357 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTG-AWSGP  59
            MDF  LPPEIN  RMY+GPG  PMLAA TAWDGLA EL +TAA Y + ++ LTG  W GP
Sbjct  1    MDFAALPPEINPIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +S SM +A  PY+AWM+ T + AE    QA  A  A+EAAFA TVPP  +AANR QL  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ GQNTPAI  TEA Y EMWAQDAAAMYGYA  SA AS +T FT+P QTT+   L 
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATP--QWVTDLGNL  237
            +QS+AV Q   +  G   Q+  PQL+SAVP +LQGLA P A+    A P    +  L N 
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  238  --------------STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSV-LVTQNGQGVSALL  282
                          S+ + G V+  Y  P V+ P+    +  I +V L  Q    V  + 
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADINAVALGAQESAAVPPMG  300

Query  283  GKIGGKPITGALAPLAEFALHTPILGSE---GLGGGSVSAGIGRAGLVGKLSVPQGW  336
               G      A +P +  +L  P+LG E    LG G +SAG+ +A LVG++SVPQ W
Sbjct  301  SGEGNPSWIPAASPASPESL--PVLGEETAATLGTGGISAGMNQAELVGRMSVPQSW  355


>gi|342859619|ref|ZP_08716272.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342132751|gb|EGT85971.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=458

 Score =  242 bits (617),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 184/405 (46%), Positives = 232/405 (58%), Gaps = 37/405 (9%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALT-GAWSGP  59
            MDF +LPPE+NS RMY GPG GPMLAAA AWD +A  L  TA  Y +E++ALT G W GP
Sbjct  1    MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDEVAAALQTTANSYQAEITALTSGPWVGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +M +A  PY+ WM      AE    QAR A  AYE AFA TVPPPV+ ANR QL  L
Sbjct  61   SSAAMVAAITPYLEWMRTAGAQAEETANQARTAAFAYETAFAETVPPPVVTANRTQLAAL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ GQNTPAI  TEA+Y EMWA+D AAM+GYAG++A+A+R+T F++P  T+N G   
Sbjct  121  VATNVLGQNTPAIAATEAEYGEMWARDTAAMFGYAGTTASATRLTPFSQPDPTSNSG--A  178

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTD-LGNLS  238
             QS AVAQ  A  A G+ ++   Q  SAVP  L   AL      A+ +P   TD LG  S
Sbjct  179  GQSEAVAQ--AGTAAGSTRNTVQQSFSAVPNLLSNAAL----SPAAISPTSATDLLGLES  232

Query  239  TFLGGAVTGPYTFPGV----------LPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGK  288
              +   +  P +  G+          LP      L G  +  +     GV A        
Sbjct  233  DLIAIFLDAPASVAGLGIDAPGTLVALPFDVAGALTGFHTDDIVSGWAGVQAW-------  285

Query  289  PITGALAPLAEFALHTPILGSEGLGGGSV-SAGIGRAGLVGKLSVPQGWTVAAPEIPSPA  347
            P TGA+ P + F    P++ +   G G++ SAG+G+A  VG LSVP GWT AAP I   A
Sbjct  286  PGTGAVPP-SPF----PVITNPAGGFGTLASAGLGQASTVGGLSVPPGWTAAAPAIRPAA  340

Query  348  AAL----QATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTG  388
              L          AA  AA+ G G+L G MA + +AGRA AG+ G
Sbjct  341  LVLPATTAGAAAPAAAAAASTGTGSLFGEMATASMAGRAMAGTGG  385


>gi|289574372|ref|ZP_06454599.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538803|gb|EFD43381.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=384

 Score =  240 bits (613),  Expect = 3e-61, Method: Compositional matrix adjust.
 Identities = 181/380 (48%), Positives = 226/380 (60%), Gaps = 29/380 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGA-AQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         +G  G +    A  P 
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITS--WRALGWIGSRGRRSCRAARRPS  288

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAA  357
            A              G G VSAG+G A  +GKLSVP  W  A+P + +P     +  L +
Sbjct  289  ARVC-----------GTGPVSAGLGNAATIGKLSVPPNWAGASPSL-APTVGSASAPLVS  336

Query  358  APIAATD--GAGALLGGMAL  375
              +   +   AG LLGGM L
Sbjct  337  DIVEQPEAGAAGNLLGGMPL  356


>gi|118466613|ref|YP_881225.1| PPE family protein [Mycobacterium avium 104]
 gi|118167900|gb|ABK68797.1| ppe family protein [Mycobacterium avium 104]
Length=446

 Score =  236 bits (602),  Expect = 5e-60, Method: Compositional matrix adjust.
 Identities = 192/418 (46%), Positives = 241/418 (58%), Gaps = 39/418 (9%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            M F +LPPE+NSGRMY+GPG G MLAAA+AWD LA ELH TAA   S +S LT   W GP
Sbjct  1    MHFAVLPPEVNSGRMYSGPGSGSMLAAASAWDELANELHVTAANIESVISGLTSEPWQGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            S+ ++ +AAA  V W++ATA  A   GAQ + A  AYE+A+A TVPP V+AANR++L  L
Sbjct  61   SAAAVTAAAATQVEWLTATAEQAAQTGAQLKAAATAYESAYAMTVPPSVVAANRSRLASL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ GQNTPAI  TE  Y EMWAQD AAMYGYAG++  ASR+T FT P +TTN   +G
Sbjct  121  VATNLLGQNTPAIAATEVAYGEMWAQDVAAMYGYAGAAQAASRVTPFTPPQRTTNEAGMG  180

Query  180  AQSSAVAQTAATAAGGNLQSAF--PQLLSAVPRALQGLALPTASQSASATPQWVTDLGNL  237
            AQ+++VAQ A T+A G++QSA      +SAVP ALQ LA  ++S SA++       L + 
Sbjct  181  AQNASVAQAAGTSA-GHVQSAVSNSNAMSAVPNALQNLASSSSSSSAAS------GLSDF  233

Query  238  STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIG---------GK  288
            S+FL      PY             L+ + S     NG G+  + G  G          +
Sbjct  234  SSFL-----NPYN------------LVSLGSAFFG-NGTGLIGVSGAAGFISDAEHKMTE  275

Query  289  PITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAA  348
            P   + A  A   L  P  GS   G  +VSAG+GRA  +G +SVPQGW+ AAPE+   A 
Sbjct  276  PSAKSKAVAAPERLEPPA-GSRSSGATTVSAGMGRASSLGGMSVPQGWSTAAPELRLTAL  334

Query  349  ALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGS-TGHPIGSAAAPAVGAAAAA  405
               A   A        G   L GG  L GL GR AA S  G   G A     G  AAA
Sbjct  335  QAPAAAAAPPGRPGPFGEMPLFGGAPLMGLPGRGAADSRDGRSSGDAGTAGRGRRAAA  392


>gi|240169037|ref|ZP_04747696.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=391

 Score =  236 bits (602),  Expect = 6e-60, Method: Compositional matrix adjust.
 Identities = 179/398 (45%), Positives = 223/398 (57%), Gaps = 54/398 (13%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASEL-SALTGAWSGP  59
            MDFG LPPEINS RMYTGPG G +LAAA  WDG+A++L+  A+   S +   L G W G 
Sbjct  1    MDFGALPPEINSARMYTGPGSGSLLAAAQVWDGVAIDLYNAASAVQSVIWGLLVGPWRGT  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            S+  M +AA+PYV W+  TA  AEL   Q R A  AYEAAFA TVPP VIA NR QL+ L
Sbjct  61   SAGLMVAAASPYVTWLGTTAAQAELTADQVRTAATAYEAAFATTVPPAVIAGNRIQLLTL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASR-MTAFTEPPQTTNHGQL  178
            IA+N+FGQNTPAI +TEA Y EMWAQDAAAMYGYAGS+A A+  +T F E P+ TN G L
Sbjct  121  IASNLFGQNTPAIAVTEADYGEMWAQDAAAMYGYAGSAAVAAETLTPFDESPEITNAGGL  180

Query  179  GAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLS  238
              Q+ AV +   TAA         QL+S VP+ALQ LA P                    
Sbjct  181  VQQAGAVEEATDTAAAN-------QLISTVPQALQQLAEP--------------------  213

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIG----GKPITGAL  294
                G  T P+T  G L  +  P+L  I +++   N   VS L   +        +   +
Sbjct  214  ----GQGTTPFTAVGELWKAISPHLSPISNIVSMLNNH-VSMLSSGMSMTNTASSLLKGM  268

Query  295  APLAEFALHTPI-------------LGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAP  341
            AP A  A+ + +             LG+ G+GG  V+AG+GRA  +G LSVP GW  AA 
Sbjct  269  APAAAQAVESAVESGARAMGSLGSGLGTSGIGGSGVAAGLGRALSIGSLSVPHGW-AAAN  327

Query  342  EIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLA  379
            +   PAA  +A  LA    AA  G   +LGG+ L  LA
Sbjct  328  QTVVPAA--RALPLAGVATAAETGPAPMLGGLPLGQLA  363


>gi|333991947|ref|YP_004524561.1| PPE family protein [Mycobacterium sp. JDM601]
 gi|333487915|gb|AEF37307.1| PPE family protein [Mycobacterium sp. JDM601]
Length=463

 Score =  232 bits (591),  Expect = 9e-59, Method: Compositional matrix adjust.
 Identities = 173/405 (43%), Positives = 223/405 (56%), Gaps = 26/405 (6%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            MDFGL+PPEI S  MY GPGPGP+ A A AWDGLA EL A +A YAS ++ LT   W G 
Sbjct  1    MDFGLVPPEIQSALMYAGPGPGPISATAAAWDGLAAELDAASASYASLVTDLTSTGWLGS  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            ++  MA+A +PY+AWM  TAV      AQ R  +AAYE AFAATVPPPVIA NRA+L+ L
Sbjct  61   TAALMAAAVSPYLAWMHTTAVQCAETAAQVRAGVAAYEEAFAATVPPPVIATNRAELLTL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNT AI   +A+Y EMWAQDAAAM+GYA +++TA+++T FT PP+T N     
Sbjct  121  LATNIFGQNTAAIAANQAEYAEMWAQDAAAMFGYASAASTATQLTPFTAPPKTANSDGSD  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQ----------------GLALPTASQS  223
              ++A AQ A +A     Q+A    L+ VP+ LQ                G A       
Sbjct  181  NTTAAAAQAAGSATATQTQNA----LAGVPQTLQQLALPMAAPAAADPVVGQATAAGVSG  236

Query  224  ASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSV-LVTQNGQGVSALL  282
             SA+  + T +G+ + F         +F     PS    +  +  + LVT  G   S  +
Sbjct  237  ISASSAYHTIIGSANFFQRIYSQFQSSFAASNEPSTTDIMERLNRIGLVT--GAVDSDEV  294

Query  283  GKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSA--GIGRAGLVGKLSVPQGWTVAA  340
            G+       G L        H      +G     +SA   +G +GLVG LSVP  W  A 
Sbjct  295  GRAADGGPLGTLGLGGFGDWHNWARFFKGFPLLKLSAAGSMGESGLVGGLSVPPTWAEAL  354

Query  341  PEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAG  385
            P++   AA    T + AAP AA  G G L    AL+G+AGRA AG
Sbjct  355  PDVRLAAAETTGTGVNAAPSAAGGGFGMLGAQAALTGMAGRALAG  399


>gi|118466467|ref|YP_882538.1| PPE family protein [Mycobacterium avium 104]
 gi|118167754|gb|ABK68651.1| ppe family protein [Mycobacterium avium 104]
 gi|212596108|gb|ACJ35552.1| PPE29 [Mycobacterium avium subsp. avium]
Length=417

 Score =  232 bits (591),  Expect = 1e-58, Method: Compositional matrix adjust.
 Identities = 213/423 (51%), Positives = 262/423 (62%), Gaps = 14/423 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFG LPPEINSGR+Y+GPG  P+LAAA AW GLA E+H+ AA Y S ++ L   W GPS
Sbjct  1    MDFGSLPPEINSGRIYSGPGSAPLLAAAAAWHGLAAEMHSAAASYGSAIAELRTLWHGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            ST+MA+AAAP++AW+  TAV AE   AQA  A AAY++ FAATVPPPVIAANRA L  LI
Sbjct  61   STAMAAAAAPFIAWLDGTAVQAEQTAAQATAAAAAYDSVFAATVPPPVIAANRALLASLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN+ GQNTPAI  TEA Y EMWAQDAAAMY YAG+SA A+R+T F  PPQT +      
Sbjct  121  ATNVLGQNTPAIAATEAHYAEMWAQDAAAMYAYAGASAVATRLTPFGAPPQTADANAAAD  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDL-GNLST  239
            QS+A A    ++   +++SA  Q +S VP A Q  A  TA  +A+  P  +TD+ G L T
Sbjct  181  QSAAAASALQSSTASSVESALSQAVSQVPVAAQVNA--TAVTAAAQLPLSLTDITGILKT  238

Query  240  F--LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
            F  + G ++GPYT  GV   +   Y + +    V    QG+  LL     K +TG LAPL
Sbjct  239  FNSVMGTISGPYTPLGVANLAKNWYQIALSIPSVGTGIQGIGPLLHP---KALTGVLAPL  295

Query  298  AEFALHTPILGSEGLGG-GSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLA  356
                L T   GS  L   G+VSA  GRAGLVG LSVP  W  A P + + AA L  T L 
Sbjct  296  LRSDLLT---GSTALSSAGTVSASAGRAGLVGALSVPANWASAVPAVRTVAAELPETMLD  352

Query  357  AAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIF  416
            AAP  A +G   + G  ALS LAGRA  G+    +  +     G  A AV+DLAT + + 
Sbjct  353  AAPAMAVNGQQGMFGPTALSSLAGRAVGGTATRAVAGSTVRVPG--AVAVDDLATTSTVI  410

Query  417  VIP  419
            VIP
Sbjct  411  VIP  413


>gi|333990650|ref|YP_004523264.1| PPE family protein [Mycobacterium sp. JDM601]
 gi|333486619|gb|AEF36011.1| PPE family protein [Mycobacterium sp. JDM601]
Length=386

 Score =  231 bits (589),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 142/242 (59%), Positives = 174/242 (72%), Gaps = 9/242 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALT-GAWSGP  59
            MDFG LPPEINS R+Y G GPG +LAAATAW  LA EL++ AA Y S ++ LT G+W+GP
Sbjct  1    MDFGALPPEINSARIYAGAGPGSLLAAATAWQELATELNSAAASYGSVIAGLTTGSWAGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS +MA+AA PY+ W++AT   A+ A AQ   A+AAYE AFAATVPPP+I ANR+    L
Sbjct  61   SSVAMAAAAGPYITWLNATGAQAQQAAAQVSAAVAAYETAFAATVPPPLITANRSLQATL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTN-HGQL  178
             ATNI GQNT AI  TEA Y+EMWAQD AAMYGYAG+SA A+R++ FT PPQTT+  GQ+
Sbjct  121  TATNILGQNTAAIATTEADYLEMWAQDTAAMYGYAGASALATRVSPFTSPPQTTDPSGQI  180

Query  179  GAQSSAVAQTAATAAGGN---LQSAFPQLLSAVPRALQGLALP---TASQSASATPQWVT  232
              QS +VAQ+AA   G +   L S  PQL+SA P ALQGLA P   T S ++SA+   +T
Sbjct  181  -TQSYSVAQSAAATTGTDTEALMSQGPQLISATPTALQGLAAPATETPSNASSASLSGLT  239

Query  233  DL  234
             L
Sbjct  240  SL  241


>gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895080|gb|EFG74799.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=459

 Score =  230 bits (587),  Expect = 3e-58, Method: Compositional matrix adjust.
 Identities = 180/366 (50%), Positives = 221/366 (61%), Gaps = 30/366 (8%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MD+G+LPPEINS RMY GPG G ML AA AWD LA EL + AA Y++ +S LT AW GPS
Sbjct  1    MDYGVLPPEINSARMYAGPGSGSMLTAAAAWDELATELRSIAASYSAVISGLTTAWLGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            ST MA+AAAPY AW++ATA  AE +G+QAR A AAYEAAFAATVPPPVI  NRA+L  LI
Sbjct  61   STRMAAAAAPYAAWLNATAAQAEQSGSQARAAAAAYEAAFAATVPPPVIETNRAELESLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN FGQNT AI   EA+Y  MWAQDAAAMYGYAG SA A+ +T F  P Q TN      
Sbjct  121  ATNTFGQNTAAIAANEARYARMWAQDAAAMYGYAGQSAAAAAVTPFDPPAQNTNPAGTAG  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ---SASATPQWVTDLGNL  237
            Q++AV+Q   T+AG N Q+A   L SA P AL+ LA P A     ++S      +   + 
Sbjct  181  QTAAVSQVVGTSAGTNSQAALSHLTSATPSALRSLAAPAAVNPPSASSLASFLSSLNSSP  240

Query  238  STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
               L G V        ++P + +P            N   +S ++G + G    G L   
Sbjct  241  LAKLAGNVE-------LIPKAVLP-----------ANDVLISTIMGLVIGARHLGDLTVA  282

Query  298  AEFALHTPILGSEGLG------GGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQ  351
             + A  TP L + GLG      G +VSA +G+AGLVG L+VP  W VA P I + AA L 
Sbjct  283  VKAA--TPGLAA-GLGYAAPALGSTVSATVGQAGLVGGLAVPPSWAVATPAIRTVAAVLS  339

Query  352  ATRLAA  357
             T  +A
Sbjct  340  GTSESA  345


>gi|307079711|ref|ZP_07488881.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308362459|gb|EFP51310.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=376

 Score =  229 bits (584),  Expect = 6e-58, Method: Compositional matrix adjust.
 Identities = 186/383 (49%), Positives = 232/383 (61%), Gaps = 30/383 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGA-AQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITS-----WRALGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEI-PS--PAAALQATR  354
            A          +   G G VSAG+G A  +GKLS+P  W  A+P + P+   A+A   + 
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSD  338

Query  355  LAAAPIAATDGAGALLGGMALSG  377
            +   P A    AG LLGGM L+G
Sbjct  339  IVEQPEA--GAAGNLLGGMPLAG  359


>gi|336458159|gb|EGO37142.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=445

 Score =  229 bits (584),  Expect = 7e-58, Method: Compositional matrix adjust.
 Identities = 190/419 (46%), Positives = 240/419 (58%), Gaps = 42/419 (10%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            M F +LPPE+NSGRMY+GPG G MLAA +AWD LA ELH TAA   S +S LT   W GP
Sbjct  1    MHFAVLPPEVNSGRMYSGPGSGSMLAA-SAWDELANELHVTAANIESVISGLTSEPWQGP  59

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            S+ ++ +AAA  V W++ATA  A   GAQ + A  AYE+A+A TVPP V+AANR++L  L
Sbjct  60   SAAAVTAAAATQVEWLTATAEQAAQTGAQLKAAATAYESAYAMTVPPSVVAANRSRLASL  119

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ GQNTPAI  TE  Y EMWAQD AAMYGYAG++  ASR+T FT P +TTN   +G
Sbjct  120  VATNLLGQNTPAIAATEVAYGEMWAQDVAAMYGYAGAAQAASRVTPFTPPQRTTNEAGMG  179

Query  180  AQSSAVAQTAATAAGGNLQSAF--PQLLSAVPRALQGLALPTASQSASATPQWVTDLGNL  237
            AQ+++VAQ A T+A G++QSA      +SAVP ALQ LA  ++S SA++       L + 
Sbjct  180  AQNASVAQAAGTSA-GHVQSAVSNSNAMSAVPNALQNLASSSSSSSAAS------GLSDF  232

Query  238  STFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
            S+FL      PY             L+ + S     NG G+  + G  G   I+ A   +
Sbjct  233  SSFL-----NPYN------------LVSLGSAFFG-NGTGLIGVSGAAGF--ISDAEHKM  272

Query  298  AEFALHT----------PILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPA  347
             E    +          P  GS   G  +VSAG+GRA  +G +SVPQGW+ AAPE+   A
Sbjct  273  TEPGAKSKAVAAPERLEPPAGSRSSGATTVSAGMGRASSLGGMSVPQGWSTAAPELRLTA  332

Query  348  AALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGS-TGHPIGSAAAPAVGAAAAA  405
                A   A        G   L GG  L GL GR AA S  G   G A     G  AAA
Sbjct  333  LQAPAAAAAPPGRPGPFGEMPLFGGAPLMGLPGRGAADSRDGRSSGDAGTAGRGRRAAA  391


>gi|340626711|ref|YP_004745163.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004901|emb|CCC44047.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=385

 Score =  228 bits (582),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 186/381 (49%), Positives = 230/381 (61%), Gaps = 30/381 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGAA-QSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEI-PS--PAAALQATR  354
            A          +   G G VSAG+G A  +GKLSVP  W  A+P + P+   A+A   + 
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPLVSD  338

Query  355  LAAAPIAATDGAGALLGGMAL  375
            +   P A    AG LLGGM L
Sbjct  339  IVEQPEA--GAAGNLLGGMPL  357


>gi|31792891|ref|NP_855384.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|224990087|ref|YP_002644774.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|289443162|ref|ZP_06432906.1| PPE family protein [Mycobacterium tuberculosis T46]
 18 more sequence titles
 Length=385

 Score =  228 bits (582),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 183/380 (49%), Positives = 228/380 (60%), Gaps = 28/380 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGAA-QSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAA  357
            A          +   G G VSAG+G A  +GKLSVP  W  A+P + +P     +  L +
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL-APTVGSASAPLVS  337

Query  358  APIAATD--GAGALLGGMAL  375
              +   +   AG LLGGM L
Sbjct  338  DIVEQPEAGAAGNLLGGMPL  357


>gi|15841163|ref|NP_336200.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881383|gb|AAK46014.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|323719795|gb|EGB28909.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=385

 Score =  227 bits (579),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 182/380 (48%), Positives = 228/380 (60%), Gaps = 28/380 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGAA-QSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAA  357
            A          +   G G VSAG+G A  +GKLS+P  W  A+P + +P     +  L +
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL-APTVGSASAPLVS  337

Query  358  APIAATD--GAGALLGGMAL  375
              +   +   AG LLGGM L
Sbjct  338  DIVEQPEAGAAGNLLGGMPL  357


>gi|57116898|ref|YP_177827.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661502|ref|YP_001283025.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148822911|ref|YP_001287665.1| PPE family protein [Mycobacterium tuberculosis F11]
 39 more sequence titles
 Length=385

 Score =  227 bits (578),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 182/380 (48%), Positives = 228/380 (60%), Gaps = 28/380 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGAA-QSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAA  357
            A          +   G G VSAG+G A  +GKLS+P  W  A+P + +P     +  L +
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL-APTVGSASAPLVS  337

Query  358  APIAATD--GAGALLGGMAL  375
              +   +   AG LLGGM L
Sbjct  338  DIVEQPEAGAAGNLLGGMPL  357


>gi|167969175|ref|ZP_02551452.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=356

 Score =  227 bits (578),  Expect = 4e-57, Method: Compositional matrix adjust.
 Identities = 172/346 (50%), Positives = 213/346 (62%), Gaps = 25/346 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AMYGYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGA-AQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEI  343
            A          +   G G VSAG+G A  +GKLS+P  W  A+P +
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL  324


>gi|57116922|ref|YP_177845.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661615|ref|YP_001283138.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967396|ref|ZP_02549673.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 11 more sequence titles
 Length=468

 Score =  227 bits (578),  Expect = 4e-57, Method: Compositional matrix adjust.
 Identities = 191/404 (48%), Positives = 225/404 (56%), Gaps = 56/404 (13%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFGL PPEI SG MY GPG GPMLAAA AWDGLA EL + AA YAS +  + + +W GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            SS  MA+AAAPYV WMS T+  A+ A  QAR A+ AYE AFAA VPPP IAANR+QL+ L
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATNIFGQNT AI  TEA+Y EMWAQD  AM+GYA SSATASR+T FT PPQTTN   L 
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  180

Query  180  AQSSAVAQTAATAAGGN-----LQSAFPQL-LSAVPRALQGLALPTASQSASATPQWVTD  233
             Q++A  Q  A A+G N     L SA  Q     +P  LQGL        A+ + Q+   
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGL--------ATLSTQYTQL  232

Query  234  LGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVT-QNGQGVSALLGKIGGKPITG  292
            +G L   + G  TG  T+               Q+V VT  N    S         P  G
Sbjct  233  MGQLINAIFGP-TGATTY---------------QNVFVTAANVTKFSTWANDAMSAPNLG  276

Query  293  ALAPLAEFALH-----TPILGSEGLGGG-------------SVSAGIGRAGLVGKLSVPQ  334
                + EF +       P +    LG G             + SAG+G+A LVG LSVP 
Sbjct  277  ----MTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPP  332

Query  335  GWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGL  378
             W  A P +   A  L AT LAAAP  AT     LLG MAL  +
Sbjct  333  SWASATPAVRLVANTLPATSLAAAP--ATQIPANLLGQMALGSM  374


>gi|289745858|ref|ZP_06505236.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289686386|gb|EFD53874.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=385

 Score =  226 bits (577),  Expect = 5e-57, Method: Compositional matrix adjust.
 Identities = 182/380 (48%), Positives = 228/380 (60%), Gaps = 28/380 (7%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59
            MDFG LPPE+NSGRMY GPG  PM+AAA+AW+GLA EL   A GY   ++ L T  W GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +ST M  A APYVAWM ATA+ AE A +QAR A AAYE AFAA VPPP+IAANRA+L  L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +  N+FGQNT +I  TEAQY EMWAQDA AM+GYAGSSATA+++T F  PP TT+     
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMHGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQ-SASATPQWVTDLGNLS  238
             Q SAVA+ A T+AG   QSA  +L++ +P  L GL  P +S  +A+ATP W      L 
Sbjct  181  TQLSAVAKAAGTSAGA-AQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGW------LE  233

Query  239  TFLGGAVTGPYTFPGVLPPSGVPYL-LGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
             F+   +     F   +   G+PY  +GI + L+T         LG IG +    A A  
Sbjct  234  WFINWYLPISQLFYNTV---GLPYFAIGIGNSLITSWRA-----LGWIGPEAAEAAAAAP  285

Query  298  AEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAA  357
            A          +   G G VSAG+G A  +GKLSVP  W  A+P + +P     +  L +
Sbjct  286  AAVG-------AAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL-APTVGSASAPLVS  337

Query  358  APIAATD--GAGALLGGMAL  375
              +   +   AG LLGGM L
Sbjct  338  DIVEQPEAGAAGNLLGGMPL  357


>gi|296167733|ref|ZP_06849950.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897076|gb|EFG76691.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=406

 Score =  226 bits (575),  Expect = 7e-57, Method: Compositional matrix adjust.
 Identities = 164/380 (44%), Positives = 208/380 (55%), Gaps = 19/380 (5%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP  59
            +DFG  PPE NS RMYTGPGP  + AAA+AW+GLA EL++TA GY   ++AL+G  W GP
Sbjct  2    IDFGAAPPEYNSARMYTGPGPEALTAAASAWNGLAAELNSTALGYDKVITALSGEEWLGP  61

Query  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119
            +S SMA A APYVAWM  TA  AE    Q   A  AYE A AATVPPP++AANRAQ   L
Sbjct  62   ASASMAQAVAPYVAWMRTTAAQAEQTANQMHAAATAYETALAATVPPPLVAANRAQTAQL  121

Query  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG  179
            +ATN+ G NTPAI   EAQY EMWAQDA+ MY YAG SA A+++  FT  PQ  N     
Sbjct  122  LATNVLGLNTPAIAQLEAQYGEMWAQDASTMYSYAGQSAAATKVAPFTAAPQIANPSAQA  181

Query  180  AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQW------VTD  233
             Q +AVA     +A  + QS     +S+ P  LQ LA P A+QS++ +  +      +T 
Sbjct  182  TQGTAVANATGNSAASSTQSVLSHAVSSTPNTLQALAAPAATQSSTTSAPFSEIWYLLTG  241

Query  234  LGNLSTFLGGAVTGPYTFPGV-LPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGG-KPIT  291
               L T LG  V G   F  +     G+PY     SV +   G  ++   G + G  P  
Sbjct  242  QTTLPTSLGSFVNGYNPFSALWYNTEGLPYF----SVGMGNFGVQIAKTTGLLNGAAPAV  297

Query  292  GALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLV-GKLSVPQGWTVAAPEIPSPAAAL  350
             AL            L   G      +A +G A  V G+LSVP  W+ A+   P    A+
Sbjct  298  KAL----PGLGGLGGLLGGGATAAHPAAALGNAASVGGRLSVPVSWSAASTPAPVLGQAI  353

Query  351  QATRLAAAPIAATDGAGALL  370
              + ++AAP  AT   G LL
Sbjct  354  PVSTVSAAP-DATAAPGNLL  372


>gi|336457980|gb|EGO36967.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=417

 Score =  226 bits (575),  Expect = 8e-57, Method: Compositional matrix adjust.
 Identities = 211/423 (50%), Positives = 261/423 (62%), Gaps = 14/423 (3%)

Query  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPS  60
            MDFG LPPEINSGR+Y+GPG  P+LAAA AW GLA E+H+ AA Y S ++ L   W GPS
Sbjct  1    MDFGSLPPEINSGRIYSGPGSAPLLAAAAAWHGLAAEMHSAAASYGSAIAELRTLWHGPS  60

Query  61   STSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLI  120
            ST+MA+AAAP++AW+  TA  AE   AQA  A AAY++ FAATVPPPVIAANRA L  LI
Sbjct  61   STAMAAAAAPFIAWLGGTAAQAEQTAAQATAAAAAYDSVFAATVPPPVIAANRALLASLI  120

Query  121  ATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGA  180
            ATN+ GQNTPAI  TEA Y EMWAQDAAAMY YAG+SA A+R+T F  PPQ+ +      
Sbjct  121  ATNVLGQNTPAIAATEAHYAEMWAQDAAAMYAYAGASAVATRLTLFGAPPQSADANAAAD  180

Query  181  QSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDL-GNLST  239
            QS+A A    ++   +++SA  Q +S VP A Q  A  TA  +A+  P  +TD+ G L T
Sbjct  181  QSAAAASALQSSTASSVESALSQGVSQVPVAAQVNA--TAVTAAAQLPLSLTDITGILKT  238

Query  240  F--LGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPL  297
            F  + G ++GPYT  GV   +   Y + +    V    QG+  LL     K +TG LAPL
Sbjct  239  FNSVMGTISGPYTPLGVANLAKNWYQIALSIPSVGTGIQGIGPLLHP---KALTGVLAPL  295

Query  298  AEFALHTPILGSEGLGG-GSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLA  356
                L T   GS  L   G+VSA  GRAGLVG LSVP  W  A P + + AA L  T L 
Sbjct  296  LRSDLLT---GSTALSSAGTVSASAGRAGLVGSLSVPANWASAVPAVRTVAAELPETMLD  352

Query  357  AAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIF  416
            AAP  A +G   + G  ALS LAGRA  G+    +  +     G  A AV+DLAT + + 
Sbjct  353  AAPAMAVNGQQGMFGPTALSSLAGRAVGGTATRAVAGSTVRVPG--AVAVDDLATTSTVI  410

Query  417  VIP  419
            VIP
Sbjct  411  VIP  413



Lambda     K      H
   0.314    0.127    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 859091811192


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40