BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1808 Length=409 Score E Sequences producing significant alignments: (Bits) Value gi|167967397|ref|ZP_02549674.1| PPE family protein [Mycobacteriu... 767 0.0 gi|57116921|ref|YP_177844.1| PPE family protein [Mycobacterium t... 766 0.0 gi|294996719|ref|ZP_06802410.1| PPE family protein [Mycobacteriu... 766 0.0 gi|31792997|ref|NP_855490.1| PPE family protein [Mycobacterium b... 765 0.0 gi|308372058|ref|ZP_07427232.2| putative PPE family protein [Myc... 747 0.0 gi|254550816|ref|ZP_05141263.1| PPE family protein [Mycobacteriu... 738 0.0 gi|15841278|ref|NP_336315.1| PPE family protein [Mycobacterium t... 718 0.0 gi|307084423|ref|ZP_07493536.1| putative PPE family protein [Myc... 635 3e-180 gi|183981478|ref|YP_001849769.1| PPE family protein [Mycobacteri... 384 2e-104 gi|183982691|ref|YP_001850982.1| PPE family protein, PPE32 [Myco... 345 6e-93 gi|118618457|ref|YP_906789.1| PPE family protein [Mycobacterium ... 342 8e-92 gi|240172862|ref|ZP_04751521.1| PPE family protein [Mycobacteriu... 338 8e-91 gi|289447416|ref|ZP_06437160.1| PPE family protein [Mycobacteriu... 311 2e-82 gi|339294738|gb|AEJ46849.1| PPE family protein [Mycobacterium tu... 308 1e-81 gi|15841271|ref|NP_336308.1| PPE family protein [Mycobacterium t... 307 2e-81 gi|289574478|ref|ZP_06454705.1| PPE family protein [Mycobacteriu... 307 3e-81 gi|339631855|ref|YP_004723497.1| PPE family protein [Mycobacteri... 306 3e-81 gi|212596550|gb|ACJ35587.1| PPE18 [Mycobacterium intracellulare ... 297 2e-78 gi|340626811|ref|YP_004745263.1| PPE family protein [Mycobacteri... 294 1e-77 gi|240171262|ref|ZP_04749921.1| PPE family protein [Mycobacteriu... 290 3e-76 gi|296164791|ref|ZP_06847351.1| PPE family protein [Mycobacteriu... 290 4e-76 gi|313658681|ref|ZP_07815561.1| PPE family protein [Mycobacteriu... 280 4e-73 gi|118462945|ref|YP_882092.1| PPE family protein [Mycobacterium ... 279 7e-73 gi|289761951|ref|ZP_06521329.1| PPE family protein [Mycobacteriu... 278 1e-72 gi|289745767|ref|ZP_06505145.1| PPE family protein [Mycobacteriu... 273 3e-71 gi|212596001|gb|ACJ35543.1| PPE18 [Mycobacterium avium subsp. av... 273 3e-71 gi|342861293|ref|ZP_08717941.1| PPE family protein [Mycobacteriu... 269 7e-70 gi|254823258|ref|ZP_05228259.1| PPE family protein [Mycobacteriu... 268 9e-70 gi|289750372|ref|ZP_06509750.1| PPE family protein [Mycobacteriu... 266 7e-69 gi|41407619|ref|NP_960455.1| hypothetical protein MAP1521 [Mycob... 266 7e-69 gi|167967221|ref|ZP_02549498.1| PPE family protein [Mycobacteriu... 264 2e-68 gi|212596574|gb|ACJ35589.1| PPE20 [Mycobacterium intracellulare ... 263 4e-68 gi|118465870|ref|YP_882096.1| PPE family protein [Mycobacterium ... 262 7e-68 gi|254775386|ref|ZP_05216902.1| PPE family protein [Mycobacteriu... 262 8e-68 gi|289757904|ref|ZP_06517282.1| PPE family protein [Mycobacteriu... 260 2e-67 gi|118466467|ref|YP_882538.1| PPE family protein [Mycobacterium ... 257 3e-66 gi|342859619|ref|ZP_08716272.1| PPE family protein [Mycobacteriu... 256 5e-66 gi|254550809|ref|ZP_05141256.1| PPE family protein [Mycobacteriu... 255 1e-65 gi|41407616|ref|NP_960452.1| hypothetical protein MAP1518 [Mycob... 254 2e-65 gi|41407250|ref|NP_960086.1| hypothetical protein MAP1152 [Mycob... 253 5e-65 gi|336457980|gb|EGO36967.1| PPE-repeat containing protein [Mycob... 247 2e-63 gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacteriu... 245 9e-63 gi|254775382|ref|ZP_05216898.1| hypothetical protein MaviaA2_120... 245 1e-62 gi|333990650|ref|YP_004523264.1| PPE family protein [Mycobacteri... 243 5e-62 gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycob... 240 4e-61 gi|148823022|ref|YP_001287776.1| PPE family protein [Mycobacteri... 238 1e-60 gi|57116922|ref|YP_177845.1| PPE family protein [Mycobacterium t... 238 1e-60 gi|212596761|gb|ACJ35604.1| PPE43 [Mycobacterium intracellulare ... 238 1e-60 gi|289447423|ref|ZP_06437167.1| PPE family protein [Mycobacteriu... 238 1e-60 gi|289443283|ref|ZP_06433027.1| PPE family protein [Mycobacteriu... 238 1e-60 >gi|167967397|ref|ZP_02549674.1| PPE family protein [Mycobacterium tuberculosis H37Ra] gi|253799148|ref|YP_003032149.1| PPE family protein [Mycobacterium tuberculosis KZN 1435] gi|254231990|ref|ZP_04925317.1| PPE family protein [Mycobacterium tuberculosis C] 24 more sequence titles Length=410 Score = 767 bits (1980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/409 (100%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 2 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 62 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 122 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 182 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 241 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 242 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 301 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL Sbjct 302 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 361 Query 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD Sbjct 362 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 410 >gi|57116921|ref|YP_177844.1| PPE family protein [Mycobacterium tuberculosis H37Rv] gi|148661614|ref|YP_001283137.1| PPE family protein [Mycobacterium tuberculosis H37Ra] gi|148823021|ref|YP_001287775.1| PPE family protein [Mycobacterium tuberculosis F11] 9 more sequence titles Length=409 Score = 766 bits (1979), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 1 MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL Sbjct 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 Query 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD Sbjct 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 >gi|294996719|ref|ZP_06802410.1| PPE family protein [Mycobacterium tuberculosis 210] gi|13377907|gb|AAK20893.1| Rv1808-like protein [Mycobacterium microti] gi|13377909|gb|AAK20894.1| Rv1808-like protein [Mycobacterium microti] gi|339294744|gb|AEJ46855.1| PPE family protein [Mycobacterium tuberculosis CCDC5079] gi|339298372|gb|AEJ50482.1| PPE family protein [Mycobacterium tuberculosis CCDC5180] Length=410 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 408/409 (99%), Gaps = 0/409 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 2 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 62 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 122 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 182 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 241 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 242 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 301 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 DITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL Sbjct 302 ADITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 361 Query 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD Sbjct 362 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 410 >gi|31792997|ref|NP_855490.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|121637710|ref|YP_977933.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990194|ref|YP_002644881.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] 29 more sequence titles Length=409 Score = 765 bits (1976), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/409 (99%), Positives = 408/409 (99%), Gaps = 0/409 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 1 MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 DITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL Sbjct 301 ADITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 Query 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD Sbjct 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 >gi|308372058|ref|ZP_07427232.2| putative PPE family protein [Mycobacterium tuberculosis SUMu004] gi|308334577|gb|EFP23428.1| putative PPE family protein [Mycobacterium tuberculosis SUMu004] Length=399 Score = 747 bits (1929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 2 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 62 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 122 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 182 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 241 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 242 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 301 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 360 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL Sbjct 302 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGAL 361 Query 361 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVA 398 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVA Sbjct 362 FGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVA 399 >gi|254550816|ref|ZP_05141263.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|297634368|ref|ZP_06952148.1| PPE family protein [Mycobacterium tuberculosis KZN 4207] gi|297731355|ref|ZP_06960473.1| PPE family protein [Mycobacterium tuberculosis KZN R506] gi|313658689|ref|ZP_07815569.1| PPE family protein [Mycobacterium tuberculosis KZN V2475] Length=395 Score = 738 bits (1905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/395 (100%), Positives = 395/395 (100%), Gaps = 0/395 (0%) Query 15 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA 74 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA Sbjct 1 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA 60 Query 75 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA 134 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA Sbjct 61 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA 120 Query 135 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA 194 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA Sbjct 121 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA 180 Query 195 SSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGA 254 SSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGA Sbjct 181 SSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGA 240 Query 255 IPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGI 314 IPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGI Sbjct 241 IPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGI 300 Query 315 ARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRAL 374 ARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRAL Sbjct 301 ARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRAL 360 Query 375 AGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 AGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD Sbjct 361 AGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 395 >gi|15841278|ref|NP_336315.1| PPE family protein [Mycobacterium tuberculosis CDC1551] gi|13881506|gb|AAK46129.1| PPE family protein [Mycobacterium tuberculosis CDC1551] Length=386 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/386 (99%), Positives = 386/386 (100%), Gaps = 0/386 (0%) Query 24 LLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQA 83 +LAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQA Sbjct 1 MLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQA 60 Query 84 EQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEM 143 EQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEM Sbjct 61 EQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEM 120 Query 144 WAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLS 203 WAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLS Sbjct 121 WAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLS 180 Query 204 QLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTF 263 QLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTF Sbjct 181 QLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTF 240 Query 264 GQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSL 323 GQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSL Sbjct 241 GQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSL 300 Query 324 SVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGA 383 SVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGA Sbjct 301 SVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGA 360 Query 384 GAARVAGGSVTEDVASTTTIIVIPAD 409 GAARVAGGSVTEDVASTTTIIVIPAD Sbjct 361 GAARVAGGSVTEDVASTTTIIVIPAD 386 >gi|307084423|ref|ZP_07493536.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012] gi|308365983|gb|EFP54834.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012] Length=336 Score = 635 bits (1639), Expect = 3e-180, Method: Compositional matrix adjust. Identities = 335/335 (100%), Positives = 335/335 (100%), Gaps = 0/335 (0%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP Sbjct 2 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL Sbjct 62 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA Sbjct 122 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL Sbjct 182 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 241 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI Sbjct 242 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 301 Query 301 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPV 335 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPV Sbjct 302 GDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPV 336 >gi|183981478|ref|YP_001849769.1| PPE family protein [Mycobacterium marinum M] gi|183174804|gb|ACC39914.1| PPE family protein [Mycobacterium marinum M] Length=427 Score = 384 bits (985), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 244/424 (58%), Positives = 290/424 (69%), Gaps = 16/424 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMY GPGSGP+LAAA WD LAAELY+ AA Y ST++GLT W GP Sbjct 1 MDFGALPPEINSGRMYVGPGSGPMLAAAVVWDELAAELYATAAGYRSTLDGLTGGSWRGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 +S +MAAA APYVAW++ TA QAE AG+QAK+AA YETAFAATVPPPVI ANRALLM L Sbjct 61 ASASMAAAAAPYVAWMTATAAQAELAGSQAKVAASAYETAFAATVPPPVIAANRALLMGL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 V TNIFGQNTPAIAATEAHYAEMWAQDAAAMY YAGSSATA+Q+ PF+EPPQ T+PS Sbjct 121 VFTNIFGQNTPAIAATEAHYAEMWAQDAAAMYAYAGSSATATQVTPFTEPPQITSPSGAV 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTV-------- 232 +Q+A V +AA A+ASSDITAQLS LI+++P+ LQ +AT+ +A AG V Sbjct 181 SQAAAVTEAATASASSDITAQLSPLIAVVPNALQGMATSGNPAAAIAGLPDVALPAGIIT 240 Query 233 -LQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP-KAAAGALS 290 LQ+ TTIL L GP++I GL +PGG +L FGQ+ +QN G A P + G L+ Sbjct 241 DLQNFTTILDTLDGPFTIQGLTGVPGGPFLAFGQVYAFSQNMVGAQAFFSPAEPVIGGLA 300 Query 291 PL---APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLP-GT 346 PL A L + +GG A+G + A VG++SVPQGW + AP +R S LP Sbjct 301 PLAGEANLGAAGVVGGPSVGGQASGAMGHAALVGNMSVPQGWTQEAPAIRVFVSELPTSV 360 Query 347 GAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGS--VTEDVASTTTII 404 AAPA A+F +MALSSLAGRAL A SG G V E + TII Sbjct 361 TAAPAATLAGESAVFNQMALSSLAGRALGTGAFGSGGGGGASKAIGGVVAEADPAAATII 420 Query 405 VIPA 408 VIPA Sbjct 421 VIPA 424 >gi|183982691|ref|YP_001850982.1| PPE family protein, PPE32 [Mycobacterium marinum M] gi|183176017|gb|ACC41127.1| PPE family protein, PPE32 [Mycobacterium marinum M] Length=426 Score = 345 bits (886), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 260/430 (61%), Positives = 306/430 (72%), Gaps = 30/430 (6%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMY GPG+ PL+AAAAAWD LAAEL S AASYGST++GLTVAPW G Sbjct 2 IDFGALPPEINSGRMYVGPGAAPLIAAAAAWDELAAELQSMAASYGSTVQGLTVAPWTGA 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAA APYV WI+ T QAEQA QAK+AAG YETAFAATVPPPVI ANRALLM+L Sbjct 62 SSITMAAAAAPYVTWINTTGVQAEQAATQAKLAAGAYETAFAATVPPPVIAANRALLMAL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAIAA EA Y EMWAQDAAAMY YAG++A AS L PF+EPPQTTNP A A Sbjct 122 IATNIFGQNTPAIAAAEAQYLEMWAQDAAAMYAYAGTAAAASALTPFTEPPQTTNPVAGA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASA--------GW-DT 231 AQSA VAQA+ AASSD+ +QL+ LI+ +P+ LQ+LATT+ A +A++ W T Sbjct 182 AQSAAVAQASSTAASSDVVSQLAGLITSVPNALQTLATTSAAPTAASILPEVSLPPWLAT 241 Query 232 VLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSP 291 L + TI+A LTGP+S+ G+ +IPGG +L+FGQ+ QNA G+ A PKA G L+P Sbjct 242 NLANWNTIMATLTGPFSLQGISSIPGGPFLSFGQVYAYVQNAQGLNAFYSPKAITGTLAP 301 Query 292 LAPLRGGYIGDITPLGGGAT---------GGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 L P +I+P G G T G + RA VGS+SVPQGW +AAP MR V+SV Sbjct 302 LVP-------EISPGGVGLTSASVSNSVSGTMGRAALVGSMSVPQGWTQAAPAMRLVSSV 354 Query 343 LPGTGAAPALAAEAPGA--LFGEMALSSLAGRALAGTAV--RSGAGAARVAGGSVTEDVA 398 L T A A A PG +FG+MALSSLAGRA+ + SG A GG V E Sbjct 355 L-STNLAAAPTAGLPGEAGVFGQMALSSLAGRAMGASTFGSSSGGAVANSLGGVVAEADP 413 Query 399 STTTIIVIPA 408 + TIIVIPA Sbjct 414 AAATIIVIPA 423 >gi|118618457|ref|YP_906789.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118570567|gb|ABL05318.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=426 Score = 342 bits (876), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 259/430 (61%), Positives = 305/430 (71%), Gaps = 30/430 (6%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMY GPG+ PL+AAAAAWD LAAEL S AASYGST++GLTVAPW G Sbjct 2 IDFGALPPEINSGRMYVGPGAAPLIAAAAAWDELAAELQSMAASYGSTVQGLTVAPWTGA 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSITMAAA APYV WI+ T QAEQA QAK+AAG YETA AATVPPPVI ANRALLM+L Sbjct 62 SSITMAAAAAPYVTWINTTGVQAEQAATQAKLAAGAYETASAATVPPPVIAANRALLMAL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAIAA EA Y EMWAQDAAAMY YAG++A AS L PF+EPPQTTNP A A Sbjct 122 IATNIFGQNTPAIAAAEAQYLEMWAQDAAAMYAYAGTAAAASALTPFTEPPQTTNPVAGA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASA--------GW-DT 231 AQSA VAQA+ AASSD+ +QL+ LI+ +P+ LQ+LATT+ A +A++ W T Sbjct 182 AQSAAVAQASSTAASSDVVSQLAGLITSVPNALQTLATTSAAPTAASILPEVSLPPWLAT 241 Query 232 VLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSP 291 L + TI+A LTGP+S+ G+ +IPGG +L+FGQ+ QNA G+ A PKA G L+P Sbjct 242 NLANWNTIMATLTGPFSLQGISSIPGGPFLSFGQVYAYVQNAQGLNAFYSPKAITGTLAP 301 Query 292 LAPLRGGYIGDITPLGGGAT---------GGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 L P +I+P G G T G + RA VGS+SVPQGW +AAP MR V+SV Sbjct 302 LVP-------EISPGGVGLTSASVSNSVSGTMGRAALVGSMSVPQGWTQAAPAMRLVSSV 354 Query 343 LPGTGAAPALAAEAPGA--LFGEMALSSLAGRALAGTAV--RSGAGAARVAGGSVTEDVA 398 L T A A A PG +FG+MALSSLAGRA+ + SG A GG V E Sbjct 355 L-STNLAAAPTAGLPGEAGVFGQMALSSLAGRAMGASTFGSSSGGAVANSLGGVVAEADP 413 Query 399 STTTIIVIPA 408 + TIIVIPA Sbjct 414 AAATIIVIPA 423 >gi|240172862|ref|ZP_04751521.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=431 Score = 338 bits (868), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 262/429 (62%), Positives = 303/429 (71%), Gaps = 23/429 (5%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMY GPG+GP+LAAAAAW LAAEL S AASY S +E LTV W GP Sbjct 2 IDFGALPPEINSGRMYVGPGAGPMLAAAAAWQELAAELQSMAASYRSIVESLTVGSWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSI MAAAVAPY+AWI+ T QAEQA AQA AA YETAFAATVPPPVI ANRALLM+L Sbjct 62 SSIAMAAAVAPYLAWINSTGAQAEQAAAQAAAAAAAYETAFAATVPPPVIAANRALLMAL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAIAATEA Y EMWAQDAAAMY YAGSSATA+QL PF+EPP TTNPSA A Sbjct 122 IATNIFGQNTPAIAATEAEYLEMWAQDAAAMYAYAGSSATAAQLTPFTEPPATTNPSAAA 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAG------------ 228 AQSA VA AAG AA+SDIT QLSQLI+ +P+ LQSLA+T + +A+ Sbjct 182 AQSAAVAPAAGTAAASDITTQLSQLIASVPNALQSLASTTSLPTAAPSLPGSIFPLPALP 241 Query 229 -W-DTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP-KAA 285 W T + + I+A L GPYS+ GL AIPGG +L+FGQ+ AQNA G+ A P K Sbjct 242 PWLATDIDNWNIIMAALNGPYSLQGLAAIPGGPFLSFGQVYAYAQNAQGLQAFFAPSKPI 301 Query 286 AGALSPLAPLRGGYIGDITPLGGGA--TGGIARAIYVGSLSVPQGWAEAAPVMRAVASVL 343 GAL+P+A G + + GG TG + RA VGS++VPQGW +AAP MR V+S+L Sbjct 302 TGALAPIADSLGANLTSSSAGSGGGPVTGAMGRAALVGSMAVPQGWTQAAPAMRLVSSLL 361 Query 344 PGT---GAAPALAAEAPGALFGEMALSSLAGRALAGTAVRS-GAGAARVAGGSVTEDVAS 399 P A A + EA +FG+MALSSLAGRALA T S G+G A GG V + Sbjct 362 PTNLAAAPAAAFSGEA--GVFGQMALSSLAGRALAATTFGSAGSGTASSLGGVVAGADPA 419 Query 400 TTTIIVIPA 408 TIIVIPA Sbjct 420 AATIIVIPA 428 >gi|289447416|ref|ZP_06437160.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] gi|289420374|gb|EFD17575.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] Length=423 Score = 311 bits (796), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 230/421 (55%), Positives = 275/421 (66%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMGL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + PGAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 IAATDGPGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|339294738|gb|AEJ46849.1| PPE family protein [Mycobacterium tuberculosis CCDC5079] Length=423 Score = 308 bits (789), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 229/421 (55%), Positives = 274/421 (66%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLSIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + GAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|15841271|ref|NP_336308.1| PPE family protein [Mycobacterium tuberculosis CDC1551] gi|31792989|ref|NP_855482.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|57116916|ref|YP_177840.1| PPE family protein [Mycobacterium tuberculosis H37Rv] 57 more sequence titles Length=423 Score = 307 bits (787), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 229/421 (55%), Positives = 274/421 (66%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + GAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|289574478|ref|ZP_06454705.1| PPE family protein [Mycobacterium tuberculosis K85] gi|289538909|gb|EFD43487.1| PPE family protein [Mycobacterium tuberculosis K85] Length=423 Score = 307 bits (786), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 228/421 (55%), Positives = 274/421 (66%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQD+AAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 IL-ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGEVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + GAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|339631855|ref|YP_004723497.1| PPE family protein [Mycobacterium africanum GM041182] gi|339331211|emb|CCC26893.1| PPE family protein [Mycobacterium africanum GM041182] Length=423 Score = 306 bits (785), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 228/421 (55%), Positives = 274/421 (66%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQD+AAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + GAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 IAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|212596550|gb|ACJ35587.1| PPE18 [Mycobacterium intracellulare ATCC 13950] Length=414 Score = 297 bits (760), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 256/419 (62%), Positives = 309/419 (74%), Gaps = 15/419 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPE+NSGRMY G GSGPLLAAAAAWDAL AELYS AA+Y STI G+TV W+GP Sbjct 1 MDFGALPPEVNSGRMYVGAGSGPLLAAAAAWDALGAELYSYAAAYSSTIAGMTVGSWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 ++ +M+AA A YVAW + TA QAEQ QA++AA YETAFAATVPPPVI ANR+LLM+L Sbjct 61 AAASMSAAAARYVAWATATAAQAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNT AIAA EA YAEMWAQDA AMY YA SSA A++L PF+EPP+TT+ SA A Sbjct 121 IATNILGQNTAAIAAAEAEYAEMWAQDAVAMYAYAASSAAATRLTPFTEPPRTTDSSAVA 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 QSA A +A+SDI ++LS LI++ P+ LQ LA T +A +A+ +++++I I Sbjct 181 RQSA----AIAQSAASDIPSELSALINVTPTMLQGLAATPSAAAATPA-ASIIEAIYPIT 235 Query 241 ANL-------TGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL 292 A L TG YS IG +PGGWWL Q LGL+QNAPGVA LL G KA AG LSPL Sbjct 236 AALRPFFAAVTGAYSPIGAIIVPGGWWLLSLQALGLSQNAPGVAELLGGGKAIAGGLSPL 295 Query 293 APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPG--TGAAP 350 APLRGGY+ +TP GG G + RA VGSLSVPQGWA AAPVM+ VASVLPG GA P Sbjct 296 APLRGGYVSAVTPEIGGVAGSMGRATLVGSLSVPQGWATAAPVMKTVASVLPGASLGAVP 355 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 A+ A + GA+FGEMA++S+AGRALAG VR+ + + + VA+T TIIV+PAD Sbjct 356 AMTATSQGAMFGEMAMASVAGRALAGAGVRTVSNGTTGVAAAAADGVATTATIIVVPAD 414 >gi|340626811|ref|YP_004745263.1| PPE family protein [Mycobacterium canettii CIPT 140010059] gi|340005001|emb|CCC44149.1| PPE family protein [Mycobacterium canettii CIPT 140010059] Length=423 Score = 294 bits (753), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 228/421 (55%), Positives = 273/421 (65%), Gaps = 14/421 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE A AQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAAAQARLAVAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN S Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHSQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTVATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAP 350 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T AAP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAP 359 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIP 407 A + GAL G MALS LAGRA AG+ + S A A A + ED+A+ I VIP Sbjct 360 MAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIP 419 Query 408 A 408 A Sbjct 420 A 420 >gi|240171262|ref|ZP_04749921.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=415 Score = 290 bits (742), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 226/423 (54%), Positives = 276/423 (66%), Gaps = 28/423 (6%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINSGRMY GPGSGP+LAAAAAWD+LAA L+S AASY S I GLT A W GP Sbjct 3 IDFGALPPEINSGRMYIGPGSGPMLAAAAAWDSLAAGLHSTAASYSSVISGLT-AGWQGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 +SITMAAA APY AWI+ TA QAEQ QA++AA +ETAFAATVPPP + ANRA LM+L Sbjct 62 ASITMAAAAAPYTAWINATAAQAEQTATQARVAAVAFETAFAATVPPPAVTANRAQLMAL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN FGQNTPAI T+A Y EMWAQDAAAMYGYAGSSATASQ+ PFSEPPQ NP+ T Sbjct 122 IATNFFGQNTPAIMGTQAEYIEMWAQDAAAMYGYAGSSATASQVTPFSEPPQIANPAGTE 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATA-----TSASAGWDTVLQS 235 Q+A VA+A A A T L QL+S +PS+LQSLA ++ + ++ S Sbjct 182 WQAAAVARATSAVAGMQ-TMSLPQLMSGVPSSLQSLAAPGSSTALAAAADPTAPASLASS 240 Query 236 ITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPL 295 + TI++ +TGP S + L I G +L Q L QN VA +AA A S Sbjct 241 LNTIISTITGPSSALSLFTIAGVPYLLGIQSYLLPQNVANVANAASKVSAASASS----- 295 Query 296 RGGYIGDITPLGGG----ATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPG---TGA 348 GG++G + GGG A+ G+ RA VG LSVPQGWA +AP ++ VA+V TGA Sbjct 296 -GGWVG-VGSAGGGLSSAASAGMGRAGLVGGLSVPQGWAMSAPAVKPVAAVFAENGLTGA 353 Query 349 APALAAEAPGALFGEMALSSLAGRALA---GTAVRSGAGAARVAGGSVTEDVASTTTIIV 405 A A + G+LF MALS LAGRA+ GTA RS + GG+ + + I + Sbjct 354 PAAAATQGEGSLFSNMALSGLAGRAMVPTGGTAARS----SGATGGATAGEASGPVNIFI 409 Query 406 IPA 408 +PA Sbjct 410 VPA 412 >gi|296164791|ref|ZP_06847351.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899845|gb|EFG79291.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=420 Score = 290 bits (741), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 239/421 (57%), Positives = 280/421 (67%), Gaps = 18/421 (4%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGALPPEINSGRMY G GSGPLLAAAAAWD LAAEL ASY S IE L PW GP Sbjct 2 LDFGALPPEINSGRMYVGAGSGPLLAAAAAWDELAAELQVTGASYNSIIETLATGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 S+I MAAA APYVAWI+ T QAE AGAQAK+AAG YE AFAATVPPPVI ANRALL +L Sbjct 62 SAIAMAAAAAPYVAWINATGAQAEAAGAQAKVAAGAYEAAFAATVPPPVIAANRALLATL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNTPAIAATEA Y EMWAQDAAAMYGYA SSATASQL PF+EPPQTTN +T Sbjct 122 IATNILGQNTPAIAATEAQYMEMWAQDAAAMYGYAASSATASQLTPFAEPPQTTNTDSTV 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDT--VLQSITT 238 Q++ + Q+ A ASS+ + LSQL + + +Q+L A + S G ++Q+ T Sbjct 182 MQASAMTQST-AQASSNTVSHLSQLSATMQPAMQTLNAGTNAGTTSTGLTVPPIVQNWNT 240 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLAPLRG 297 + +TG YS IPGG +L+FGQ QN AA L GPKA GA LAPL Sbjct 241 FWSAVTGVYSPQSWSTIPGGPFLSFGQAYAWGQNGQSAAAYLSGPKAITGA---LAPLTS 297 Query 298 GYIGDITPL-----GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPAL 352 G + P+ GG +G + +A VG++SVPQGW EAAP +R +A V+P AA Sbjct 298 G-ASAVKPMLSSAVGGQVSGSLGKAALVGNMSVPQGWTEAAPAVRTIAQVIPANLAAAPA 356 Query 353 AAEA-PGALFGEMALSSLAGRALAGTAVRS-GAGAARVA---GGSVTEDVASTTTIIVIP 407 A A +F +M LSSL GRA+A +A S GA AA+ A GG V E + TIIVIP Sbjct 357 ATLAGEEGMFSQMGLSSLLGRAVASSATHSVGATAAKAAGSLGGVVAEADPAAATIIVIP 416 Query 408 A 408 A Sbjct 417 A 417 >gi|313658681|ref|ZP_07815561.1| PPE family protein [Mycobacterium tuberculosis KZN V2475] Length=409 Score = 280 bits (715), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 217/407 (54%), Positives = 261/407 (65%), Gaps = 14/407 (3%) Query 15 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA 74 MY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GPSS +MA+A APYVA Sbjct 1 MYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGPSSTSMASAAAPYVA 59 Query 75 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA 134 W+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L+ATNIFGQNTPAI Sbjct 60 WMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIM 119 Query 135 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA 194 TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN AQS+ VAQ A AA Sbjct 120 MTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAA 179 Query 195 SSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITTILAN-LTGPYSIIG 251 ++ + QL+S +P LQ LA T + + SA+ W T L +++T L +TGPY+ G Sbjct 180 GGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPG 239 Query 252 LGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP--LRGGYIGDITPL 306 + G +L Q + + QN GV+ALLG K GAL+PLA L +G Sbjct 240 VLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLG 299 Query 307 GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAPALAAEAPGALFGEM 364 GG + GI RA VG LSVPQGW AAP + + A+ L T AAP A + GAL G M Sbjct 300 GGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGM 359 Query 365 ALSSLAGRALAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIPA 408 ALS LAGRA AG+ + S A A A + ED+A+ I VIPA Sbjct 360 ALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA 406 >gi|118462945|ref|YP_882092.1| PPE family protein [Mycobacterium avium 104] gi|118164232|gb|ABK65129.1| ppe family protein [Mycobacterium avium 104] Length=414 Score = 279 bits (713), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 253/419 (61%), Positives = 305/419 (73%), Gaps = 15/419 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPE+NSGRMY G GSGPLLAAAAAWDAL AELYS AA+Y STI GLTV W+GP Sbjct 1 MDFGALPPEVNSGRMYGGAGSGPLLAAAAAWDALGAELYSFAAAYTSTIAGLTVGSWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 ++ +M+AA AP++AW + TAGQAEQ QA++AA YETAFAATVPPPVI ANR+LLM+L Sbjct 61 AATSMSAAAAPFIAWATTTAGQAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNT AIAA EA YAEMWAQDAAAMY YA +SA A++L PF+EPP+TT + Sbjct 121 IATNILGQNTAAIAAAEAEYAEMWAQDAAAMYAYAAASAAAAELTPFTEPPRTTE----S 176 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 + +A + A +A+SD+ AQLS LI + P+ LQ LATT +A +A+ +++++I I Sbjct 177 SAAARQSAAVAQSAASDLPAQLSTLIDVTPTMLQGLATTPSAAAATPA-ASIIEAIYPIT 235 Query 241 ANL-------TGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL 292 A L TG YS IG +PGGWWL Q LGLAQNAPGVA LL G KA AG LSPL Sbjct 236 AALRPFFAAVTGAYSPIGAIILPGGWWLLSLQALGLAQNAPGVAELLGGGKAIAGGLSPL 295 Query 293 APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPAL 352 APLRGGY+ +TP GG G + R+ VGSLSVP GW AAPV+R VASVLP +A A Sbjct 296 APLRGGYVSAVTPDAGGVAGSMGRSTLVGSLSVPPGWTTAAPVLRTVASVLPAASSATAA 355 Query 353 AAEAP-GALFGEMALSSLAGRALAGTAVRS-GAGAARVAGGSVTEDVASTTTIIVIPAD 409 A A GA+FGEMA +SLAGRALAG VR+ G G A + + A+T TIIV+PAD Sbjct 356 AMPASGGAVFGEMAAASLAGRALAGAGVRTVGNGTTGAATAAAADGAATTATIIVVPAD 414 >gi|289761951|ref|ZP_06521329.1| PPE family protein [Mycobacterium tuberculosis GM 1503] gi|289709457|gb|EFD73473.1| PPE family protein [Mycobacterium tuberculosis GM 1503] Length=423 Score = 278 bits (711), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 198/354 (56%), Positives = 237/354 (67%), Gaps = 9/354 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT 346 L +G GG + GI RA VG LSVPQGW AAP + + A+ L T Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQAT 353 >gi|289745767|ref|ZP_06505145.1| PPE family protein [Mycobacterium tuberculosis 02_1987] gi|289686295|gb|EFD53783.1| PPE family protein [Mycobacterium tuberculosis 02_1987] Length=418 Score = 273 bits (699), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 192/337 (57%), Positives = 228/337 (68%), Gaps = 9/337 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGW 329 L +G GG + GI RA VG LSVPQGW Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGW 336 >gi|212596001|gb|ACJ35543.1| PPE18 [Mycobacterium avium subsp. avium] Length=414 Score = 273 bits (699), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 250/419 (60%), Positives = 304/419 (73%), Gaps = 15/419 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPE+NSGRMY G GSGPLLAAAAAWDAL AELYS AA+Y STI GLTV W+GP Sbjct 1 MDFGALPPEVNSGRMYGGAGSGPLLAAAAAWDALGAELYSFAAAYTSTIAGLTVGSWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 ++ +M+AA AP++AW + TAG+AEQ QA++AA YETAFAATVPPPVI ANR+LLM+L Sbjct 61 AATSMSAAAAPFIAWATTTAGRAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNT AIAA EA YAEMWAQDAAAMY YA +SA A++L PF+EPP+TT + Sbjct 121 IATNILGQNTAAIAAAEAEYAEMWAQDAAAMYAYAAASAAAAELTPFTEPPRTTE----S 176 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 + +A + A +A+SD+ AQLS LI + P+ LQ LATT +A +A+ +++++I I Sbjct 177 SAAARQSAAVAQSAASDLPAQLSTLIDVTPTMLQGLATTPSAAAATPA-ASIIEAIYPIT 235 Query 241 ANL-------TGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL 292 A L TG YS IG +PGGWWL Q LGLAQNAPGVA LL G KA AG LSPL Sbjct 236 AALRPFFAAVTGAYSPIGAIILPGGWWLLSLQALGLAQNAPGVAELLGGGKAIAGGLSPL 295 Query 293 APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPAL 352 APLRGGY+ + P GG G + R+ VGSLSVP GW AAPV+R VASVLP +A A Sbjct 296 APLRGGYVSAVAPDAGGVAGSMGRSTLVGSLSVPPGWTTAAPVLRTVASVLPAASSATAA 355 Query 353 AAEAP-GALFGEMALSSLAGRALAGTAVRS-GAGAARVAGGSVTEDVASTTTIIVIPAD 409 A A GA+FGEMA +S+AGRALAG VR+ G G A + + A+T TIIV+PAD Sbjct 356 AMPASGGAVFGEMAAASVAGRALAGAGVRTVGNGTTGAATAAAADGAATTATIIVVPAD 414 >gi|342861293|ref|ZP_08717941.1| PPE family protein [Mycobacterium colombiense CECT 3035] gi|342131193|gb|EGT84474.1| PPE family protein [Mycobacterium colombiense CECT 3035] Length=421 Score = 269 bits (687), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 237/423 (57%), Positives = 276/423 (66%), Gaps = 21/423 (4%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGA PPE NSGRMY G GSGPLLAAAAAWD LAAEL S ASY STIE L PW GP Sbjct 2 LDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAELQSTGASYSSTIETLATGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSI MAAA APYVAWI T QAEQAGAQAK+AAG YE AFAATVPPPVI ANR+LL +L Sbjct 62 SSIAMAAAAAPYVAWIHATGAQAEQAGAQAKLAAGAYEAAFAATVPPPVIAANRSLLATL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNI GQNTPAIAATEAHY EMWAQDAAAMY Y +SA+ASQL PF+EPP+TTN SA Sbjct 122 VATNILGQNTPAIAATEAHYMEMWAQDAAAMYAYTAASASASQLTPFAEPPRTTNDSAGP 181 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 Q+A VAQ+ G ++ + ++ LSQL + Q+ + +T +A++G L S T Sbjct 182 TQAAAVAQSTGQSSGATVS-HLSQLSTTTAPAAQAASNASTTPTAASGSSLTLPSAITNW 240 Query 241 ANL----TGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL--- 292 TGP+S +IPGG +L+FGQ QN G AA L GPKA +GAL+PL Sbjct 241 NEFWSVATGPFSPQSWSSIPGGPFLSFGQAYAWGQNGQGAAAYLAGPKAISGALAPLTSG 300 Query 293 ----APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGA 348 P+ +G G A+G + +A VGS+SVPQGW EAAP +R +A LP A Sbjct 301 ANAVKPMLSSAVG-----AGQASGSMGKAALVGSMSVPQGWTEAAPAIRTLAQGLPTNLA 355 Query 349 APALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVA---GGSVTEDVASTTTIIV 405 A A A +F +MALSSLAGRA+A A R GA V GG E + TIIV Sbjct 356 AAPAAMAAEEGVFNQMALSSLAGRAVAAAATRPAGGAGTVVGSLGGVAAEADPAAATIIV 415 Query 406 IPA 408 IP Sbjct 416 IPC 418 >gi|254823258|ref|ZP_05228259.1| PPE family protein [Mycobacterium intracellulare ATCC 13950] Length=400 Score = 268 bits (686), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 244/405 (61%), Positives = 295/405 (73%), Gaps = 15/405 (3%) Query 15 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA 74 MY G GSGPLLAAAAAWDAL AELYS AA+Y STI G+TV W+GP++ +M+AA A YVA Sbjct 1 MYVGAGSGPLLAAAAAWDALGAELYSYAAAYSSTIAGMTVGSWLGPAAASMSAAAARYVA 60 Query 75 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA 134 W + TA QAEQ QA++AA YETAFAATVPPPVI ANR+LLM+L+ATNI GQNT AIA Sbjct 61 WATATAAQAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTLIATNILGQNTAAIA 120 Query 135 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA 194 A EA YAEMWAQDA AMY YA SSA A++L PF+EPP+TT+ SA A QSA A +A Sbjct 121 AAEAEYAEMWAQDAVAMYAYAASSAAATRLTPFTEPPRTTDSSAVARQSA----AIAQSA 176 Query 195 SSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANL-------TGPY 247 +SDI ++LS LI++ P+ LQ LA T +A +A+ +++++I I A L TG Y Sbjct 177 ASDIPSELSALINVTPTMLQGLAATPSAAAATPA-ASIIEAIYPITAALRPFFAAVTGAY 235 Query 248 SIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLAPLRGGYIGDITPL 306 S IG +PGGWWL Q LGL+QNAPGVA LL G KA AG LSPLAPLRGGY+ +TP Sbjct 236 SPIGAIIVPGGWWLLSLQALGLSQNAPGVAELLGGGKAIAGGLSPLAPLRGGYVSAVTPE 295 Query 307 GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPG--TGAAPALAAEAPGALFGEM 364 GG G + RA VGSLSVPQGWA AAPVM+ VASVLPG GA PA+ A + GA+FGEM Sbjct 296 IGGVAGSMGRATLVGSLSVPQGWATAAPVMKTVASVLPGASLGAVPAMTATSQGAMFGEM 355 Query 365 ALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD 409 A++S+AGRALAG VR+ + + + VA+T TIIV+PAD Sbjct 356 AMASVAGRALAGAGVRTVSNGTTGVAAAAADGVATTATIIVVPAD 400 >gi|289750372|ref|ZP_06509750.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289690959|gb|EFD58388.1| PPE family protein [Mycobacterium tuberculosis T92] Length=333 Score = 266 bits (679), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 189/334 (57%), Positives = 225/334 (68%), Gaps = 9/334 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP 294 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAE 299 Query 295 --LRGGYIGDITPLGGGATGGIARAIYVGSLSVP 326 L +G GG + GI RA VG LSVP Sbjct 300 FALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVP 333 >gi|41407619|ref|NP_960455.1| hypothetical protein MAP1521 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395972|gb|AAS03838.1| hypothetical protein MAP_1521 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457571|gb|EGO36576.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=414 Score = 266 bits (679), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 251/419 (60%), Positives = 304/419 (73%), Gaps = 15/419 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPE+NSGRMY G GSGPLLAAAAAWDAL AELYS AA+Y STI GLTV W+GP Sbjct 1 MDFGALPPEVNSGRMYVGAGSGPLLAAAAAWDALGAELYSFAAAYTSTIAGLTVGSWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 ++ +M+AA AP++AW + TAG+AEQ QA++AA YETAFAATVPPPVI ANR+LLM+L Sbjct 61 AATSMSAAAAPFIAWATTTAGRAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNT AIAA EA YAEMWAQDAAAMY YA +SA A++L PF+EPP+TT + Sbjct 121 IATNILGQNTAAIAAAEAEYAEMWAQDAAAMYAYAAASAAATELTPFTEPPRTTE----S 176 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 + +A + A +A+SD+ AQLS LI + P+ LQ LATT +A +A+ +++++I I Sbjct 177 SAAARQSAAVAQSAASDLPAQLSTLIDVTPTMLQGLATTPSAAAATPA-ASIIEAIYPIT 235 Query 241 ANL-------TGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL 292 A L TG YS IG +PGGWWL Q LGLAQNAPGVA LL G KA AG LSPL Sbjct 236 AALRPFFAAVTGAYSPIGAIILPGGWWLLSLQALGLAQNAPGVAELLGGGKAIAGGLSPL 295 Query 293 APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPAL 352 APLRGGY+ +TP GG G + R+ VGSLSVP GW AAPV+R V SVLP +A A Sbjct 296 APLRGGYVSAVTPDAGGVAGSMGRSTLVGSLSVPPGWTTAAPVLRTVTSVLPAASSATAA 355 Query 353 AAEAP-GALFGEMALSSLAGRALAGTAVRS-GAGAARVAGGSVTEDVASTTTIIVIPAD 409 A A GA+FGEMA +SLAGRALAG VR+ G G A + + A+T TIIV+PAD Sbjct 356 ALPASGGAVFGEMAAASLAGRALAGAGVRTVGNGTTGAATAAAADGAATTATIIVVPAD 414 >gi|167967221|ref|ZP_02549498.1| PPE family protein [Mycobacterium tuberculosis H37Ra] Length=400 Score = 264 bits (675), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 210/398 (53%), Positives = 254/398 (64%), Gaps = 14/398 (3%) Query 24 LLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQA 83 +LAAA AWD LA EL++ AA Y S + LT A W GPSS +MA+A APYVAW+S TA A Sbjct 1 MLAAATAWDGLAVELHATAAGYASELSALTGA-WSGPSSTSMASAAAPYVAWMSATAVHA 59 Query 84 EQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEM 143 E AGAQA++A YE AFAATVPPPVI ANRA LM L+ATNIFGQNTPAI TEA Y EM Sbjct 60 ELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEM 119 Query 144 WAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLS 203 WAQDAAAMYGYAGSSATAS++ F+EPPQTTN AQS+ VAQ A AA ++ + Sbjct 120 WAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFP 179 Query 204 QLISLLPSTLQSLA--TTATATSASAGWDTVLQSITTILAN-LTGPYSIIGLGAIPGGWW 260 QL+S +P LQ LA T + + SA+ W T L +++T L +TGPY+ G+ G + Sbjct 180 QLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPY 239 Query 261 LTFGQILGLAQNAPGVAALLGP---KAAAGALSPLAP--LRGGYIGDITPLGGGATGGIA 315 L Q + + QN GV+ALLG K GAL+PLA L +G GG + GI Sbjct 240 LLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIG 299 Query 316 RAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAPALAAEAPGALFGEMALSSLAGRA 373 RA VG LSVPQGW AAP + + A+ L T AAP A + GAL G MALS LAGRA Sbjct 300 RAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRA 359 Query 374 LAGTA---VRSGAGAARVAGGSVTEDVASTTTIIVIPA 408 AG+ + S A A A + ED+A+ I VIPA Sbjct 360 AAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPA 397 >gi|212596574|gb|ACJ35589.1| PPE20 [Mycobacterium intracellulare ATCC 13950] Length=407 Score = 263 bits (672), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 227/421 (54%), Positives = 264/421 (63%), Gaps = 31/421 (7%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGA PPE NSGRMY G GSGPLLAAAAAWD LAAEL + ASY STIE L PW GP Sbjct 2 LDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAELQTTGASYSSTIETLATGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS+ MAAA APYVAW+ T QAE+AGA+AK+AAG YE AFAATVPPPVI ANRAL Sbjct 62 SSLAMAAAAAPYVAWMHATGAQAEEAGARAKLAAGAYEAAFAATVPPPVIAANRAL---- 117 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 NTPAIAATEAHY EMWAQDAAAMYGYA SSA+AS L PF+ PP+TTN SA Sbjct 118 --------NTPAIAATEAHYMEMWAQDAAAMYGYAASSASASALTPFAPPPRTTNDSAGP 169 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDT--VLQSITT 238 AQ+A VAQ+ G + S+ T QLSQL L QS+A ++ ++SA T + + Sbjct 170 AQAAAVAQSGGQSGSNTAT-QLSQLSGTLQPAAQSVANAGSSGTSSAELTTPSFITNWNE 228 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPL----- 292 + +TG YS IPGG +L+FGQ QN G AA L GPKA +GAL+PL Sbjct 229 FWSVVTGVYSPQSWTTIPGGPFLSFGQAYAWGQNGQGAAAYLAGPKAISGALAPLTSGAN 288 Query 293 --APLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAP 350 P+ IG G +G + +A VG +SVPQGW EAAP +R +A LP AA Sbjct 289 AVKPMLSSAIG-----AGQVSGSMGKAALVGGMSVPQGWTEAAPAIRTLAQGLPTNLAAA 343 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVA---GGSVTEDVASTTTIIVIP 407 A +F +MALSSLAGRA+A A R GAA GG E + TIIVIP Sbjct 344 PAALAGEEGVFSQMALSSLAGRAVAAAATRPVGGAATAMGALGGVAAEADPAAATIIVIP 403 Query 408 A 408 Sbjct 404 C 404 >gi|118465870|ref|YP_882096.1| PPE family protein [Mycobacterium avium 104] gi|118167157|gb|ABK68054.1| ppe family protein [Mycobacterium avium 104] Length=419 Score = 262 bits (670), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 237/421 (57%), Positives = 273/421 (65%), Gaps = 19/421 (4%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGA PPE NSGRMY G GSGPLLAAAAAWD LAAEL S ASYGST+E LT PW GP Sbjct 2 LDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAELQSVGASYGSTVETLTTGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSI MAAA APYVAW+ T QAEQAGAQAK+AA YETAFAATVPPPVI ANRALL +L Sbjct 62 SSIAMAAAAAPYVAWLQATGAQAEQAGAQAKLAAAAYETAFAATVPPPVIAANRALLATL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNI GQNTPAIAATEAHY EMWAQDAAAMY YA SSA+A+QL PF+EPP+TTN SA Sbjct 122 VATNILGQNTPAIAATEAHYMEMWAQDAAAMYAYAASSASAAQLTPFTEPPRTTNESA-G 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDT--VLQSITT 238 + + A + S+ A LSQL + Q+ A+ T+AS T + + Sbjct 181 PLQSAAVAQSAAQSGSNTAAHLSQLSATAQPAAQAAGNAASTTAASTQLTTPSFITNWNE 240 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLA---- 293 + +TG YS IPGG +L+FGQ QN G AA L GPKA +GAL+PLA Sbjct 241 FWSVVTGVYSPQSWTTIPGGPFLSFGQAYAWGQNGQGAAAYLAGPKAISGALAPLASGGN 300 Query 294 ---PLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAP 350 P+ +G G +G + +A VGS+SVPQGW EAAP +R +A VLPG AA Sbjct 301 AVKPMLSSAVG-----AGQVSGSMGKAALVGSMSVPQGWTEAAPAIRTLAQVLPGNMAAA 355 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVA---GGSVTEDVASTTTIIVIP 407 A +F +MALSSLAGRA+A A R GAA A GG E + TIIVIP Sbjct 356 PAAMAGEEGVFSQMALSSLAGRAVAAAATRPVGGAASAASSLGGVAAEADPAAATIIVIP 415 Query 408 A 408 Sbjct 416 C 416 >gi|254775386|ref|ZP_05216902.1| PPE family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|212596025|gb|ACJ35545.1| PPE20 [Mycobacterium avium subsp. avium] Length=419 Score = 262 bits (670), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 237/421 (57%), Positives = 272/421 (65%), Gaps = 19/421 (4%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGA PPE NSGRMY G GSGPLLAAAAAWD LAAEL S ASYGST+E LT PW GP Sbjct 2 LDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAELQSVGASYGSTVETLTTGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSI MAAA APYVAW+ T QAEQAGAQAK+AA YETAFAATVPPPVI ANRALL +L Sbjct 62 SSIAMAAAAAPYVAWLQATGAQAEQAGAQAKLAAAAYETAFAATVPPPVIAANRALLATL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNI GQNTPAIAATEAHY EMWAQDAAAMY YA SSA+A+QL PF+EPP+TTN SA Sbjct 122 VATNILGQNTPAIAATEAHYMEMWAQDAAAMYAYAASSASAAQLTPFTEPPRTTNESA-G 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDT--VLQSITT 238 + + A S+ A LSQL + Q+ A+ T+AS T + + Sbjct 181 PLQSAAVAQSAAQPGSNTAAHLSQLSATAQPAAQAAGNAASTTAASTQLTTPSFITNWNE 240 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLA---- 293 + +TG YS IPGG +L+FGQ QN G AA L GPKA +GAL+PLA Sbjct 241 FWSVVTGVYSPQSWTTIPGGPFLSFGQAYAWGQNGQGAAAYLAGPKAISGALAPLASGGN 300 Query 294 ---PLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAP 350 P+ +G G +G + +A VGS+SVPQGW EAAP +R +A VLPG AA Sbjct 301 AVKPMLSSAVG-----AGQVSGSMGKAALVGSMSVPQGWTEAAPAIRTLAQVLPGNMAAA 355 Query 351 ALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVA---GGSVTEDVASTTTIIVIP 407 A +F +MALSSLAGRA+A A R GAA A GG E + TIIVIP Sbjct 356 PAAMAGEEGVFSQMALSSLAGRAVAAAATRPVGGAASAASSLGGVAAEADPAAATIIVIP 415 Query 408 A 408 Sbjct 416 C 416 >gi|289757904|ref|ZP_06517282.1| PPE family protein [Mycobacterium tuberculosis T85] gi|289713468|gb|EFD77480.1| PPE family protein [Mycobacterium tuberculosis T85] Length=305 Score = 260 bits (665), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 175/299 (59%), Positives = 209/299 (70%), Gaps = 7/299 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGP---KAAAGALSPLA 293 L +TGPY+ G+ G +L Q + + QN GV+ALLG K GAL+PLA Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLA 298 >gi|118466467|ref|YP_882538.1| PPE family protein [Mycobacterium avium 104] gi|118167754|gb|ABK68651.1| ppe family protein [Mycobacterium avium 104] gi|212596108|gb|ACJ35552.1| PPE29 [Mycobacterium avium subsp. avium] Length=417 Score = 257 bits (656), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 216/418 (52%), Positives = 275/418 (66%), Gaps = 12/418 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG+LPPEINSGR+Y+GPGS PLLAAAAAW LAAE++SAAASYGS I L W GP Sbjct 1 MDFGSLPPEINSGRIYSGPGSAPLLAAAAAWHGLAAEMHSAAASYGSAIAELRTL-WHGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA AP++AW+ TA QAEQ AQA AA Y++ FAATVPPPVI ANRALL SL Sbjct 60 SSTAMAAAAAPFIAWLDGTAVQAEQTAAQATAAAAAYDSVFAATVPPPVIAANRALLASL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN+ GQNTPAIAATEAHYAEMWAQDAAAMY YAG+SA A++L PF PPQT + +A A Sbjct 120 IATNVLGQNTPAIAATEAHYAEMWAQDAAAMYAYAGASAVATRLTPFGAPPQTADANAAA 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATS----ASAGWDTVLQSI 236 QSA A A ++ +S + + LSQ +S +P Q AT TA + + +L++ Sbjct 180 DQSAAAASALQSSTASSVESALSQAVSQVPVAAQVNATAVTAAAQLPLSLTDITGILKTF 239 Query 237 TTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLR 296 +++ ++GPY+ +G+ + W+ I + G+ LL PKA G L+PL LR Sbjct 240 NSVMGTISGPYTPLGVANLAKNWYQIALSIPSVGTGIQGIGPLLHPKALTGVLAPL--LR 297 Query 297 GGYIGDITPLG--GGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAPAL 352 + T L G + RA VG+LSVP WA A P +R VA+ LP T AAPA+ Sbjct 298 SDLLTGSTALSSAGTVSASAGRAGLVGALSVPANWASAVPAVRTVAAELPETMLDAAPAM 357 Query 353 AAEAPGALFGEMALSSLAGRALAGTAVRSGAGA-ARVAGGSVTEDVASTTTIIVIPAD 409 A +FG ALSSLAGRA+ GTA R+ AG+ RV G +D+A+T+T+IVIP + Sbjct 358 AVNGQQGMFGPTALSSLAGRAVGGTATRAVAGSTVRVPGAVAVDDLATTSTVIVIPPN 415 >gi|342859619|ref|ZP_08716272.1| PPE family protein [Mycobacterium colombiense CECT 3035] gi|342132751|gb|EGT85971.1| PPE family protein [Mycobacterium colombiense CECT 3035] Length=458 Score = 256 bits (654), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 190/421 (46%), Positives = 236/421 (57%), Gaps = 62/421 (14%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DF LPPE+NS RMYAGPGSGP+LAAA AWD +AA L + A SY + I LT PW+GP Sbjct 1 MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDEVAAALQTTANSYQAEITALTSGPWVGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS M AA+ PY+ W+ QAE+ QA+ AA YETAFA TVPPPV+ ANR L +L Sbjct 61 SSAAMVAAITPYLEWMRTAGAQAEETANQARTAAFAYETAFAETVPPPVVTANRTQLAAL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATN+ GQNTPAIAATEA Y EMWA+D AAM+GYAG++A+A++L PFS+P T+N + A Sbjct 121 VATNVLGQNTPAIAATEAEYGEMWARDTAAMFGYAGTTASATRLTPFSQPDPTSN--SGA 178 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 QS VAQA AA S+ T Q Q S +P+ L + A + A S ++ D + I Sbjct 179 GQSEAVAQAGTAAGSTRNTVQ--QSFSAVPNLLSNAALSPAAISPTSATDLLGLESDLIA 236 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYI 300 L P S+ GLG +APG L P AGAL+ G + Sbjct 237 IFLDAPASVAGLGI-----------------DAPGTLVAL-PFDVAGALT------GFHT 272 Query 301 GDI-------------------------TPLGGG---ATGGIARAIYVGSLSVPQGWAEA 332 DI P GG A+ G+ +A VG LSVP GW A Sbjct 273 DDIVSGWAGVQAWPGTGAVPPSPFPVITNPAGGFGTLASAGLGQASTVGGLSVPPGWTAA 332 Query 333 APVMRAVASVL------PGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAA 386 AP +R A VL AA A A+ G+LFGEMA +S+AGRA+AGT G A Sbjct 333 APAIRPAALVLPATTAGAAAPAAAAAASTGTGSLFGEMATASMAGRAMAGTGGALGRERA 392 Query 387 R 387 R Sbjct 393 R 393 >gi|254550809|ref|ZP_05141256.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=284 Score = 255 bits (651), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 168/284 (60%), Positives = 201/284 (71%), Gaps = 4/284 (1%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG LPPEINSGRMY GPG GP+LAAA AWD LA EL++ AA Y S + LT A W GP Sbjct 1 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGA-WSGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS +MA+A APYVAW+S TA AE AGAQA++A YE AFAATVPPPVI ANRA LM L Sbjct 60 SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNIFGQNTPAI TEA Y EMWAQDAAAMYGYAGSSATAS++ F+EPPQTTN Sbjct 120 IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLG 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLA--TTATATSASAGWDTVLQSITT 238 AQS+ VAQ A AA ++ + QL+S +P LQ LA T + + SA+ W T L +++T Sbjct 180 AQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLST 239 Query 239 ILAN-LTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLG 281 L +TGPY+ G+ G +L Q + + QN GV+ALLG Sbjct 240 FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLG 283 >gi|41407616|ref|NP_960452.1| hypothetical protein MAP1518 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395969|gb|AAS03835.1| hypothetical protein MAP_1518 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457567|gb|EGO36572.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=419 Score = 254 bits (649), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 234/420 (56%), Positives = 271/420 (65%), Gaps = 17/420 (4%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDFGA PPE NSGRMY G GSGPLLAAAAAWD LAAEL S ASYGST+E LT PW GP Sbjct 2 LDFGAYPPEYNSGRMYVGAGSGPLLAAAAAWDELAAELQSVGASYGSTVETLTTGPWTGP 61 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SSI MAAA APYVAW+ T QAEQAGAQAK+AA YETAFAATVPPPVI ANRALL +L Sbjct 62 SSIAMAAAAAPYVAWLQATGAQAEQAGAQAKLAAAAYETAFAATVPPPVIAANRALLATL 121 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATN+ GQNTPAIAATEAHY EMWAQDAAAMY YA SSA+A+QL PF+EPP+TTN SA Sbjct 122 VATNMLGQNTPAIAATEAHYMEMWAQDAAAMYAYAASSASAAQLTPFTEPPRTTNESA-G 180 Query 181 AQSAVVAQAAGAAASSDITAQLSQL--ISLLPSTLQSLATTATATSASAGWDTVLQSITT 238 + + A + S+ A LSQL + + A + T S + + + Sbjct 181 PLQSAAVAQSAAQSGSNTAAHLSQLSATAQPAAQAAGNAASTTTASTQLTTPSFITNWNE 240 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLAPLRG 297 + +TG YS IPGG +L+FGQ QN G AA L GPKA +GAL+PLA G Sbjct 241 FWSVVTGVYSPQSWSTIPGGPFLSFGQAYAWGQNGQGAAAYLAGPKAISGALAPLA--SG 298 Query 298 GYIGDITPL------GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPA 351 G + P+ G +G + +A VGS+SVPQGW EAAP +R +A VLPG AA Sbjct 299 G--NAVKPMLSSAVGAGQVSGSMGKAALVGSMSVPQGWTEAAPAIRTLAQVLPGNMAAAP 356 Query 352 LAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVA---GGSVTEDVASTTTIIVIPA 408 A +F +MALSSLAGRA+A A R GAA A GG E + TIIVIP Sbjct 357 AAMAGEEGVFSQMALSSLAGRAVAAAATRPVGGAAAAANSLGGVAAEADPAAATIIVIPC 416 >gi|41407250|ref|NP_960086.1| hypothetical protein MAP1152 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395602|gb|AAS03469.1| hypothetical protein MAP_1152 [Mycobacterium avium subsp. paratuberculosis K-10] Length=416 Score = 253 bits (645), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 208/418 (50%), Positives = 267/418 (64%), Gaps = 13/418 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG+LPPEINSGR+Y+GPGS PLLAAAAAW LAAE++SAAASYGS I L W GP Sbjct 1 MDFGSLPPEINSGRIYSGPGSAPLLAAAAAWHGLAAEMHSAAASYGSAIAELRTL-WHGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA AP++AW+ + A AA Y++ FAATVPPPVI ANRALL SL Sbjct 60 SSTAMAAAAAPFIAWLG-GTAAQAEQTAAQATAAAAYDSVFAATVPPPVIAANRALLASL 118 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN+ GQNTPAIAATEAHYAEMWAQDAAAMY YAG+SA A++L PF PPQ+ + +A A Sbjct 119 IATNVLGQNTPAIAATEAHYAEMWAQDAAAMYAYAGASAVATRLTPFGAPPQSADANAAA 178 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATS----ASAGWDTVLQSI 236 QSA A A + +S + + LSQ +S +P Q AT TA + + +L++ Sbjct 179 DQSAAAASALQLSTASSVESALSQGVSQVPVAAQVNATAVTAAAQLPLSLTDITGILKTF 238 Query 237 TTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLR 296 +++ ++GPY+ +G+ + W+ I + G+ LL PKA G L+PL LR Sbjct 239 NSVMGTISGPYTPLGVANLAKNWYQIALSIPSVGTGIQGIGPLLHPKALTGVLAPL--LR 296 Query 297 GGYIGDITPLG--GGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAPAL 352 + T L G + RA VGSLSVP WA A P +R VA+ LP T AAPA+ Sbjct 297 SDLLTGSTALSSAGTVSASAGRAGLVGSLSVPANWASAVPAVRTVAAELPETMLDAAPAM 356 Query 353 AAEAPGALFGEMALSSLAGRALAGTAVRSGAGA-ARVAGGSVTEDVASTTTIIVIPAD 409 A +FG ALSSLAGRA+ GTA R+ AG+ RV G +D+A+T+T+IVIP + Sbjct 357 AVNGQQGMFGPTALSSLAGRAVGGTATRAVAGSTVRVPGAVAVDDLATTSTVIVIPPN 414 >gi|336457980|gb|EGO36967.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=417 Score = 247 bits (631), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 215/418 (52%), Positives = 274/418 (66%), Gaps = 12/418 (2%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG+LPPEINSGR+Y+GPGS PLLAAAAAW LAAE++SAAASYGS I L W GP Sbjct 1 MDFGSLPPEINSGRIYSGPGSAPLLAAAAAWHGLAAEMHSAAASYGSAIAELRTL-WHGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA AP++AW+ TA QAEQ AQA AA Y++ FAATVPPPVI ANRALL SL Sbjct 60 SSTAMAAAAAPFIAWLGGTAAQAEQTAAQATAAAAAYDSVFAATVPPPVIAANRALLASL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN+ GQNTPAIAATEAHYAEMWAQDAAAMY YAG+SA A++L F PPQ+ + +A A Sbjct 120 IATNVLGQNTPAIAATEAHYAEMWAQDAAAMYAYAGASAVATRLTLFGAPPQSADANAAA 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATS----ASAGWDTVLQSI 236 QSA A A ++ +S + + LSQ +S +P Q AT TA + + +L++ Sbjct 180 DQSAAAASALQSSTASSVESALSQGVSQVPVAAQVNATAVTAAAQLPLSLTDITGILKTF 239 Query 237 TTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLR 296 +++ ++GPY+ +G+ + W+ I + G+ LL PKA G L+PL LR Sbjct 240 NSVMGTISGPYTPLGVANLAKNWYQIALSIPSVGTGIQGIGPLLHPKALTGVLAPL--LR 297 Query 297 GGYIGDITPLG--GGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--GAAPAL 352 + T L G + RA VGSLSVP WA A P +R VA+ LP T AAPA+ Sbjct 298 SDLLTGSTALSSAGTVSASAGRAGLVGSLSVPANWASAVPAVRTVAAELPETMLDAAPAM 357 Query 353 AAEAPGALFGEMALSSLAGRALAGTAVRSGAGA-ARVAGGSVTEDVASTTTIIVIPAD 409 A +FG ALSSLAGRA+ GTA R+ AG+ RV G +D+A+T+T+IVIP + Sbjct 358 AVNGQQGMFGPTALSSLAGRAVGGTATRAVAGSTVRVPGAVAVDDLATTSTVIVIPPN 415 >gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895080|gb|EFG74799.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=459 Score = 245 bits (626), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 189/366 (52%), Positives = 229/366 (63%), Gaps = 14/366 (3%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +D+G LPPEINS RMYAGPGSG +L AAAAWD LA EL S AASY + I GLT A W+GP Sbjct 1 MDYGVLPPEINSARMYAGPGSGSMLTAAAAWDELATELRSIAASYSAVISGLTTA-WLGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APY AW++ TA QAEQ+G+QA+ AA YE AFAATVPPPVIE NRA L SL Sbjct 60 SSTRMAAAAAPYAAWLNATAAQAEQSGSQARAAAAAYEAAFAATVPPPVIETNRAELESL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN FGQNT AIAA EA YA MWAQDAAAMYGYAG SA A+ + PF P Q TNP+ TA Sbjct 120 IATNTFGQNTAAIAANEARYARMWAQDAAAMYGYAGQSAAAAAVTPFDPPAQNTNPAGTA 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATAT--SASAGWDTVLQSITT 238 Q+A V+Q G +A ++ A LS L S PS L+SLA A SAS+ + ++ Sbjct 180 GQTAAVSQVVGTSAGTNSQAALSHLTSATPSALRSLAAPAAVNPPSASSLASFLSSLNSS 239 Query 239 ILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAAL-LGPKAAAGALSPLAPLRG 297 LA L G +I +P L I+GL A + L + KAA L+ Sbjct 240 PLAKLAGNVELIPKAVLPANDVL-ISTIMGLVIGARHLGDLTVAVKAATPGLA------- 291 Query 298 GYIGDITP-LGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTG-AAPALAAE 355 +G P LG + + +A VG L+VP WA A P +R VA+VL GT +A A A Sbjct 292 AGLGYAAPALGSTVSATVGQAGLVGGLAVPPSWAVATPAIRTVAAVLSGTSESAVAAATV 351 Query 356 APGALF 361 + G+ F Sbjct 352 SEGSFF 357 >gi|254775382|ref|ZP_05216898.1| hypothetical protein MaviaA2_12036 [Mycobacterium avium subsp. avium ATCC 25291] Length=400 Score = 245 bits (625), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 238/405 (59%), Positives = 290/405 (72%), Gaps = 15/405 (3%) Query 15 MYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVA 74 MY G GSGPLLAAAAAWDAL AELYS AA+Y STI GLTV W+GP++ +M+AA AP++A Sbjct 1 MYGGAGSGPLLAAAAAWDALGAELYSFAAAYTSTIAGLTVGSWLGPAATSMSAAAAPFIA 60 Query 75 WISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIA 134 W + TAG+AEQ QA++AA YETAFAATVPPPVI ANR+LLM+L+ATNI GQNT AIA Sbjct 61 WATTTAGRAEQVATQARLAAAAYETAFAATVPPPVIAANRSLLMTLIATNILGQNTAAIA 120 Query 135 ATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAA 194 A EA YAEMWAQDAAAMY YA +SA A++L PF+EPP+TT ++ +A + A +A Sbjct 121 AAEAEYAEMWAQDAAAMYAYAAASAAAAELTPFTEPPRTTE----SSAAARQSAAVAQSA 176 Query 195 SSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANL-------TGPY 247 +SD+ AQLS LI + P+ LQ LATT +A +A+ +++++I I A L TG Y Sbjct 177 ASDLPAQLSTLIDVTPTMLQGLATTPSAAAATPA-ASIIEAIYPITAALRPFFAAVTGAY 235 Query 248 SIIGLGAIPGGWWLTFGQILGLAQNAPGVAALL-GPKAAAGALSPLAPLRGGYIGDITPL 306 S IG +PGGWWL Q LGLAQNAPGVA LL G KA AG LSPLAPLRGGY+ + P Sbjct 236 SPIGAIILPGGWWLLSLQALGLAQNAPGVAELLGGGKAIAGGLSPLAPLRGGYVSAVAPD 295 Query 307 GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAP-GALFGEMA 365 GG G + R+ VGSLSVP GW AAPV+R VASVLP +A A A A GA+FGEMA Sbjct 296 AGGVAGSMGRSTLVGSLSVPPGWTTAAPVLRTVASVLPAASSATAAAMPASGGAVFGEMA 355 Query 366 LSSLAGRALAGTAVRS-GAGAARVAGGSVTEDVASTTTIIVIPAD 409 +S+AGRALAG VR+ G G A + + A+T TIIV+PAD Sbjct 356 AASVAGRALAGAGVRTVGNGTTGAATAAAADGAATTATIIVVPAD 400 >gi|333990650|ref|YP_004523264.1| PPE family protein [Mycobacterium sp. JDM601] gi|333486619|gb|AEF36011.1| PPE family protein [Mycobacterium sp. JDM601] Length=386 Score = 243 bits (619), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 142/230 (62%), Positives = 165/230 (72%), Gaps = 3/230 (1%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFGALPPEINS R+YAG G G LLAAA AW LA EL SAAASYGS I GLT W GP Sbjct 1 MDFGALPPEINSARIYAGAGPGSLLAAATAWQELATELNSAAASYGSVIAGLTTGSWAGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS+ MAAA PY+ W++ T QA+QA AQ A YETAFAATVPPP+I ANR+L +L Sbjct 61 SSVAMAAAAGPYITWLNATGAQAQQAAAQVSAAVAAYETAFAATVPPPLITANRSLQATL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 ATNI GQNT AIA TEA Y EMWAQD AAMYGYAG+SA A++++PF+ PPQTT+PS Sbjct 121 TATNILGQNTAAIATTEADYLEMWAQDTAAMYGYAGASALATRVSPFTSPPQTTDPSGQI 180 Query 181 AQSAVVAQAAGAAASSDITAQLS---QLISLLPSTLQSLATTATATSASA 227 QS VAQ+A A +D A +S QLIS P+ LQ LA AT T ++A Sbjct 181 TQSYSVAQSAAATTGTDTEALMSQGPQLISATPTALQGLAAPATETPSNA 230 >gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478] Length=401 Score = 240 bits (612), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 194/394 (50%), Positives = 236/394 (60%), Gaps = 22/394 (5%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 LDF LPPEINS RMY+GPGSGP+LAAA+AW +LAAEL + A SY S + LT W GP Sbjct 5 LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP 64 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 +S +MAAA APYVAW++ TA QAEQ QA+ AAG YE AF ATVPPPVI ANRA LM+L Sbjct 65 ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL 124 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATNI GQNTPAIAATEA Y EMWAQDA AMYGYAGSSA A+QL+PF EP Q TNPS A Sbjct 125 IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA 184 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQS---IT 237 AQ+A V +A+ +A + ++ LS LIS++PS LQ L+ + + WD + S Sbjct 185 AQAAAVTEASANSAGNQ-SSTLSGLISMVPSALQGLSGPNSTSWLQVIWDLLTGSGPAWW 243 Query 238 TILANLTGPYSII-------GLGAIPGGWWLTF-GQILGLAQNAPGVAALLGPKAAAGAL 289 L N+ GP + + GL +PG + F +L A A A G+ Sbjct 244 QTLWNVWGPNANVWNTITSTGL-FVPGSTFAPFMASVLAGAVAADAAQDASAAAAGVGSG 302 Query 290 SPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--- 346 PL G + G + G+ A VG LSVP W AAP+ + S L GT Sbjct 303 LAAGPLAS--TGSV---GSAVSAGLGNAGIVGKLSVPPAWTAAAPLHSPLGSALGGTPMV 357 Query 347 GAAPALAAEAPGALFGEMALSSLAGRALAGTAVR 380 PA+AA PG FG MA GRA+ R Sbjct 358 APPPAVAAGMPGMPFGNMAGQPF-GRAVPQYGFR 390 >gi|148823022|ref|YP_001287776.1| PPE family protein [Mycobacterium tuberculosis F11] gi|253799147|ref|YP_003032148.1| PPE family protein [Mycobacterium tuberculosis KZN 1435] gi|254364637|ref|ZP_04980683.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem] gi|289554417|ref|ZP_06443627.1| PPE family protein [Mycobacterium tuberculosis KZN 605] gi|134150151|gb|EBA42196.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem] gi|148721549|gb|ABR06174.1| PPE family protein [Mycobacterium tuberculosis F11] gi|253320650|gb|ACT25253.1| PPE family protein [Mycobacterium tuberculosis KZN 1435] gi|289439049|gb|EFD21542.1| PPE family protein [Mycobacterium tuberculosis KZN 605] Length=470 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 197/425 (47%), Positives = 248/425 (59%), Gaps = 34/425 (8%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG PPEI SG MY GPG+GP+LAAA AWD LAAEL S AASY S +EG+ W+GP Sbjct 3 MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP 62 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APYV W+S T+ QA+ A QA+ A YETAFAA VPPP I ANR+ L+SL Sbjct 63 SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL 122 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNT AIAATEA Y EMWAQD AM+GYA SSATAS+L PF+ PPQTTNPS A Sbjct 123 VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA 182 Query 181 AQSAVVAQAAGAAASSD-ITAQLSQL-----ISLLPSTLQSLATTATATSASAGW----- 229 Q+A QA A+ ++ +T LS ++P+ LQ LAT +T + G Sbjct 183 GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI 242 Query 230 -----DTVLQSITTILANLTGPYSIIGLGAIPG-GWWLTFGQILGLAQNAPGVAALLGPK 283 T Q++ AN+T +S A+ +T ++ AP + PK Sbjct 243 FGPTGATTYQNLFVTAANVTK-FSTWANDAMSAPNLGMTEFKVFWQPPPAPEI-----PK 296 Query 284 AAAGA-LSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 ++ GA L LR G L A+ G+ +A VG LSVP WA A P +R VA+ Sbjct 297 SSLGAGLG----LRSGLSAG---LAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANT 349 Query 343 LPGTGAAPALAAEAPGALFGEMALSSL--AGRALAGTAVRSGAGA-ARVAGGSVTEDVAS 399 LP T A A A + P L G+MAL S+ A A+ +G+GA AR GG+ + + Sbjct 350 LPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVK 409 Query 400 TTTII 404 +I Sbjct 410 LEAVI 414 >gi|57116922|ref|YP_177845.1| PPE family protein [Mycobacterium tuberculosis H37Rv] gi|148661615|ref|YP_001283138.1| PPE family protein [Mycobacterium tuberculosis H37Ra] gi|167967396|ref|ZP_02549673.1| PPE family protein [Mycobacterium tuberculosis H37Ra] 11 more sequence titles Length=468 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 197/425 (47%), Positives = 248/425 (59%), Gaps = 34/425 (8%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG PPEI SG MY GPG+GP+LAAA AWD LAAEL S AASY S +EG+ W+GP Sbjct 1 MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APYV W+S T+ QA+ A QA+ A YETAFAA VPPP I ANR+ L+SL Sbjct 61 SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNT AIAATEA Y EMWAQD AM+GYA SSATAS+L PF+ PPQTTNPS A Sbjct 121 VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA 180 Query 181 AQSAVVAQAAGAAASSD-ITAQLSQL-----ISLLPSTLQSLATTATATSASAGW----- 229 Q+A QA A+ ++ +T LS ++P+ LQ LAT +T + G Sbjct 181 GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI 240 Query 230 -----DTVLQSITTILANLTGPYSIIGLGAIPG-GWWLTFGQILGLAQNAPGVAALLGPK 283 T Q++ AN+T +S A+ +T ++ AP + PK Sbjct 241 FGPTGATTYQNVFVTAANVTK-FSTWANDAMSAPNLGMTEFKVFWQPPPAPEI-----PK 294 Query 284 AAAGA-LSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 ++ GA L LR G L A+ G+ +A VG LSVP WA A P +R VA+ Sbjct 295 SSLGAGLG----LRSGLSAG---LAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANT 347 Query 343 LPGTGAAPALAAEAPGALFGEMALSSL--AGRALAGTAVRSGAGA-ARVAGGSVTEDVAS 399 LP T A A A + P L G+MAL S+ A A+ +G+GA AR GG+ + + Sbjct 348 LPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVK 407 Query 400 TTTII 404 +I Sbjct 408 LEAVI 412 >gi|212596761|gb|ACJ35604.1| PPE43 [Mycobacterium intracellulare ATCC 13950] Length=409 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 223/424 (53%), Positives = 280/424 (67%), Gaps = 34/424 (8%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG +PPE+NSGRMY+GPG+GP+LAAAAAW+ALAA+L++AAASY S I LT A W GP Sbjct 1 MDFGVMPPEVNSGRMYSGPGAGPMLAAAAAWEALAAQLHAAAASYESVISNLT-AGWRGP 59 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APY AW+S TA QAEQ +QA+ A YE AF ATVPPPVI ANRA LM+L Sbjct 60 SSSMMAAAAAPYAAWMSATAAQAEQTASQARAAVVAYEAAFLATVPPPVIAANRAQLMAL 119 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 +ATN GQNTPAI ATEA YAEMWAQDAAAMYGYAG+SA A+Q+ PF+ PP++TNP+ TA Sbjct 120 IATNFLGQNTPAIMATEAQYAEMWAQDAAAMYGYAGASAAAAQVTPFAPPPRSTNPAGTA 179 Query 181 AQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTIL 240 Q+A VAQA G + +++ + L QL+S +P +LQ+L T A A+A ++L + + L Sbjct 180 GQAAAVAQATGGSVATNTESALPQLMSSVPQSLQTLTTPA----AAADPPSLLSAFDSAL 235 Query 241 ANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAA----LLGPKAAAGALSPLAPLR 296 GP S+ G+G P + L L + QN V + L ++A G L Sbjct 236 TGPLGPVSLFGIGGSP--YLLGVENYL-VPQNVANVNSARQRLDRDRSALGRL------- 285 Query 297 GGYIGDITPL-------GGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGT--- 346 GG + T + G G + GI RA VG LSVP GWA AAP +R+VA+V+P T Sbjct 286 GGEVNSGTQMVSSPRAAGTGMSPGIGRAGVVGRLSVPPGWAAAAPEIRSVATVIPQTAFA 345 Query 347 GAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAG-GSVTEDVASTTTIIV 405 GA ALAAE G+LF MA S L GRA+A T G G+AR +G G+ A+T TIIV Sbjct 346 GAPSALAAEGEGSLFSSMAASGLVGRAMAAT----GGGSARASGIGAGFGRAATTATIIV 401 Query 406 IPAD 409 I AD Sbjct 402 INAD 405 >gi|289447423|ref|ZP_06437167.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] gi|289569881|ref|ZP_06450108.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289750382|ref|ZP_06509760.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289753904|ref|ZP_06513282.1| PPE family protein [Mycobacterium tuberculosis EAS054] gi|289420381|gb|EFD17582.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] gi|289543635|gb|EFD47283.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289690969|gb|EFD58398.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289694491|gb|EFD61920.1| PPE family protein [Mycobacterium tuberculosis EAS054] Length=472 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 197/425 (47%), Positives = 248/425 (59%), Gaps = 34/425 (8%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG PPEI SG MY GPG+GP+LAAA AWD LAAEL S AASY S +EG+ W+GP Sbjct 3 MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP 62 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APYV W+S T+ QA+ A QA+ A YETAFAA VPPP I ANR+ L+SL Sbjct 63 SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL 122 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNT AIAATEA Y EMWAQD AM+GYA SSATAS+L PF+ PPQTTNPS A Sbjct 123 VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA 182 Query 181 AQSAVVAQAAGAAASSD-ITAQLSQL-----ISLLPSTLQSLATTATATSASAGW----- 229 Q+A QA A+ ++ +T LS ++P+ LQ LAT +T + G Sbjct 183 GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI 242 Query 230 -----DTVLQSITTILANLTGPYSIIGLGAIPG-GWWLTFGQILGLAQNAPGVAALLGPK 283 T Q++ AN+T +S A+ +T ++ AP + PK Sbjct 243 FGPTGATTYQNLFVTAANVTK-FSTWANDAMSAPNLGMTEFKVFWQPPPAPEI-----PK 296 Query 284 AAAGA-LSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 ++ GA L LR G L A+ G+ +A VG LSVP WA A P +R VA+ Sbjct 297 SSLGAGLG----LRSGLSAG---LAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANT 349 Query 343 LPGTGAAPALAAEAPGALFGEMALSSL--AGRALAGTAVRSGAGA-ARVAGGSVTEDVAS 399 LP T A A A + P L G+MAL S+ A A+ +G+GA AR GG+ + + Sbjct 350 LPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVK 409 Query 400 TTTII 404 +I Sbjct 410 LEAVI 414 >gi|289443283|ref|ZP_06433027.1| PPE family protein [Mycobacterium tuberculosis T46] gi|339631862|ref|YP_004723504.1| PPE family protein [Mycobacterium africanum GM041182] gi|289416202|gb|EFD13442.1| PPE family protein [Mycobacterium tuberculosis T46] gi|339331218|emb|CCC26901.1| PPE family protein [Mycobacterium africanum GM041182] Length=470 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 197/425 (47%), Positives = 248/425 (59%), Gaps = 34/425 (8%) Query 1 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP 60 +DFG PPEI SG MY GPG+GP+LAAA AWD LAAEL S AASY S +EG+ W+GP Sbjct 1 MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP 60 Query 61 SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL 120 SS MAAA APYV W+S T+ QA+ A QA+ A YETAFAA VPPP I ANR+ L+SL Sbjct 61 SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL 120 Query 121 VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATA 180 VATNIFGQNT AIAATEA Y EMWAQD AM+GYA SSATAS+L PF+ PPQTTNPS A Sbjct 121 VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA 180 Query 181 AQSAVVAQAAGAAASSD-ITAQLSQL-----ISLLPSTLQSLATTATATSASAGW----- 229 Q+A QA A+ ++ +T LS ++P+ LQ LAT +T + G Sbjct 181 GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI 240 Query 230 -----DTVLQSITTILANLTGPYSIIGLGAIPG-GWWLTFGQILGLAQNAPGVAALLGPK 283 T Q++ AN+T +S A+ +T ++ AP + PK Sbjct 241 FGPTGATTYQNLFVTAANVTK-FSTWANDAMSAPNLGMTEFKVFWQPPPAPEI-----PK 294 Query 284 AAAGA-LSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASV 342 ++ GA L LR G L A+ G+ +A VG LSVP WA A P +R VA+ Sbjct 295 SSLGAGLG----LRSGLSAG---LAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANT 347 Query 343 LPGTGAAPALAAEAPGALFGEMALSSL--AGRALAGTAVRSGAGA-ARVAGGSVTEDVAS 399 LP T A A A + P L G+MAL S+ A A+ +G+GA AR GG+ + + Sbjct 348 LPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVK 407 Query 400 TTTII 404 +I Sbjct 408 LEAVI 412 Lambda K H 0.313 0.126 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 816290083944 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40