BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1834 Length=288 Score E Sequences producing significant alignments: (Bits) Value gi|15608971|ref|NP_216350.1| hydrolase [Mycobacterium tuberculos... 577 7e-163 gi|306779833|ref|ZP_07418170.1| hydrolase [Mycobacterium tubercu... 576 2e-162 gi|31793024|ref|NP_855517.1| hydrolase [Mycobacterium bovis AF21... 576 2e-162 gi|340626842|ref|YP_004745294.1| putative hydrolase [Mycobacteri... 574 5e-162 gi|289443308|ref|ZP_06433052.1| hydrolase [Mycobacterium tubercu... 574 5e-162 gi|339294770|gb|AEJ46881.1| hydrolase [Mycobacterium tuberculosi... 510 9e-143 gi|240171758|ref|ZP_04750417.1| putative hydrolase [Mycobacteriu... 496 2e-138 gi|183982718|ref|YP_001851009.1| hydrolase [Mycobacterium marinu... 486 2e-135 gi|118618441|ref|YP_906773.1| hydrolase [Mycobacterium ulcerans ... 472 2e-131 gi|333990578|ref|YP_004523192.1| hydrolase [Mycobacterium sp. JD... 418 5e-115 gi|289750406|ref|ZP_06509784.1| hydrolase [Mycobacterium tubercu... 285 5e-75 gi|289761982|ref|ZP_06521360.1| hypothetical hydrolase [Mycobact... 251 1e-64 gi|114564776|ref|YP_752290.1| alpha/beta hydrolase fold [Shewane... 201 1e-49 gi|308047953|ref|YP_003911519.1| alpha/beta hydrolase fold prote... 189 5e-46 gi|239994052|ref|ZP_04714576.1| alpha/beta hydrolase fold protei... 187 2e-45 gi|149376888|ref|ZP_01894643.1| alpha/beta hydrolase fold protei... 187 2e-45 gi|329935911|ref|ZP_08285713.1| putative epoxide hydrolase [Stre... 183 2e-44 gi|241603782|ref|XP_002405756.1| soluble epoxide hydrolase, puta... 183 3e-44 gi|24216487|ref|NP_713968.1| putative hydrolase [Leptospira inte... 183 3e-44 gi|120556686|ref|YP_961037.1| alpha/beta hydrolase fold [Marinob... 182 4e-44 gi|311744126|ref|ZP_07717932.1| hydrolase [Aeromicrobium marinum... 182 4e-44 gi|332535392|ref|ZP_08411183.1| hydrolase, alpha/beta fold famil... 181 2e-43 gi|149922586|ref|ZP_01911015.1| probable epoxide hydrolase [Ples... 181 2e-43 gi|311696419|gb|ADP99292.1| mesoderm specific transcript isoform... 179 4e-43 gi|254447121|ref|ZP_05060588.1| hydrolase, alpha/beta fold famil... 173 3e-41 gi|221134787|ref|ZP_03561090.1| alpha/beta hydrolase fold protei... 170 2e-40 gi|254480063|ref|ZP_05093311.1| hydrolase, alpha/beta fold famil... 170 3e-40 gi|332305363|ref|YP_004433214.1| alpha/beta hydrolase fold prote... 169 3e-40 gi|85374314|ref|YP_458376.1| epoxide hydrolase [Erythrobacter li... 168 1e-39 gi|94734200|emb|CAK04921.1| mesoderm specific transcript [Danio ... 166 3e-39 gi|94734201|emb|CAK04922.1| mesoderm specific transcript [Danio ... 166 3e-39 gi|149927157|ref|ZP_01915414.1| probable epoxide hydrolase [Limn... 166 3e-39 gi|7768535|dbj|BAA95444.1| alpha/beta hydroxylase [Danio rerio] 166 3e-39 gi|342861846|ref|ZP_08718491.1| hydrolase [Mycobacterium colombi... 165 6e-39 gi|90415661|ref|ZP_01223595.1| hydrolase, alpha/beta fold family... 164 1e-38 gi|330504493|ref|YP_004381362.1| alpha/beta hydrolase fold prote... 164 2e-38 gi|37589663|gb|AAH59471.1| Mesoderm specific transcript [Danio r... 164 2e-38 gi|85708903|ref|ZP_01039969.1| hydrolase, alpha/beta fold family... 163 2e-38 gi|18859023|ref|NP_571118.1| mesoderm specific transcript [Danio... 162 6e-38 gi|146217635|gb|ABQ10905.1| mesoderm-specific transcript protein... 162 7e-38 gi|296388054|ref|ZP_06877529.1| putative epoxide hydrolase [Pseu... 162 8e-38 gi|83859043|ref|ZP_00952564.1| hydrolase, alpha/beta fold family... 162 8e-38 gi|152984185|ref|YP_001347081.1| putative epoxide hydrolase [Pse... 160 2e-37 gi|70728342|ref|YP_258091.1| alpha/beta fold family hydrolase [P... 159 5e-37 gi|260816096|ref|XP_002602808.1| hypothetical protein BRAFLDRAFT... 159 7e-37 gi|15598625|ref|NP_252119.1| epoxide hydrolase [Pseudomonas aeru... 159 7e-37 gi|116051449|ref|YP_789718.1| alpha/beta family hydrolase [Pseud... 158 7e-37 gi|149411652|ref|XP_001511333.1| PREDICTED: mesoderm-specific tr... 158 7e-37 gi|8926696|emb|CAB96533.1| mesoderm specific transcript [Takifug... 158 1e-36 gi|313108785|ref|ZP_07794772.1| putative hydrolase, alpha/beta f... 158 1e-36 >gi|15608971|ref|NP_216350.1| hydrolase [Mycobacterium tuberculosis H37Rv] gi|15841303|ref|NP_336340.1| PEG1/MEST protein [Mycobacterium tuberculosis CDC1551] gi|121637737|ref|YP_977960.1| putative hydrolase [Mycobacterium bovis BCG str. Pasteur 1173P2] 51 more sequence titles Length=288 Score = 577 bits (1487), Expect = 7e-163, Method: Compositional matrix adjust. Identities = 287/288 (99%), Positives = 288/288 (100%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA Sbjct 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD Sbjct 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 >gi|306779833|ref|ZP_07418170.1| hydrolase [Mycobacterium tuberculosis SUMu002] gi|306784575|ref|ZP_07422897.1| hydrolase [Mycobacterium tuberculosis SUMu003] gi|306788937|ref|ZP_07427259.1| hydrolase [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=288 Score = 576 bits (1484), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 286/288 (99%), Positives = 287/288 (99%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA Sbjct 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLRELRPSAAV ELPGLGHYPQVEAPKAYAEAALSLLVD Sbjct 241 PVATTNVLNGLRELRPSAAVAELPGLGHYPQVEAPKAYAEAALSLLVD 288 >gi|31793024|ref|NP_855517.1| hydrolase [Mycobacterium bovis AF2122/97] gi|31618615|emb|CAD94568.1| Probable hydrolase [Mycobacterium bovis AF2122/97] Length=288 Score = 576 bits (1484), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 286/288 (99%), Positives = 287/288 (99%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA Sbjct 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLRELRPSAAVVELPGLGHYPQ EAPKAYAEAALSLLVD Sbjct 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQAEAPKAYAEAALSLLVD 288 >gi|340626842|ref|YP_004745294.1| putative hydrolase [Mycobacterium canettii CIPT 140010059] gi|340005032|emb|CCC44181.1| putative hydrolase [Mycobacterium canettii CIPT 140010059] Length=288 Score = 574 bits (1480), Expect = 5e-162, Method: Compositional matrix adjust. Identities = 286/288 (99%), Positives = 287/288 (99%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQA LVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQADLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA Sbjct 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD Sbjct 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 >gi|289443308|ref|ZP_06433052.1| hydrolase [Mycobacterium tuberculosis T46] gi|289569906|ref|ZP_06450133.1| hydrolase [Mycobacterium tuberculosis T17] gi|289416227|gb|EFD13467.1| hydrolase [Mycobacterium tuberculosis T46] gi|289543660|gb|EFD47308.1| hydrolase [Mycobacterium tuberculosis T17] Length=288 Score = 574 bits (1479), Expect = 5e-162, Method: Compositional matrix adjust. Identities = 286/288 (99%), Positives = 287/288 (99%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLA DL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLALDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA Sbjct 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD Sbjct 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 >gi|339294770|gb|AEJ46881.1| hydrolase [Mycobacterium tuberculosis CCDC5079] gi|339298398|gb|AEJ50508.1| hydrolase [Mycobacterium tuberculosis CCDC5180] Length=254 Score = 510 bits (1314), Expect = 9e-143, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%), Gaps = 0/254 (0%) Query 35 MLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAH 94 MLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAH Sbjct 1 MLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAH 60 Query 95 TVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRS 154 TVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRS Sbjct 61 TVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRS 120 Query 155 PLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDER 214 PLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDER Sbjct 121 PLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDER 180 Query 215 IRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEA 274 IRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEA Sbjct 181 IRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEA 240 Query 275 PKAYAEAALSLLVD 288 PKAYAEAALSLLVD Sbjct 241 PKAYAEAALSLLVD 254 >gi|240171758|ref|ZP_04750417.1| putative hydrolase [Mycobacterium kansasii ATCC 12478] Length=290 Score = 496 bits (1276), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 245/288 (86%), Positives = 264/288 (92%), Gaps = 0/288 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVR WRDGGRWL TA GKVFVRSGPG PT+LLLHGYPSSSFDFR VIPHL GQAW Sbjct 1 MTSPSVRAWRDGGRWLHTAAGKVFVRSGPGAAPTLLLLHGYPSSSFDFREVIPHLAGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQA LV+ V+A T TG VVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQADLVQAVIARTTTGPVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 DGRLPFDLRRAVLSNGSVIL+RASLRPIQ+VLR PLGPVAARLV+RGGF R FG +FS Sbjct 121 DGRLPFDLRRAVLSNGSVILKRASLRPIQRVLRGPLGPVAARLVTRGGFRRSFGTLFSAG 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLS +EA+AQWELL Y+DG+RIPHLLISYL+ER+R+A+RWHGAVRDWPKPLGFVWGL D Sbjct 181 HPLSDEEAEAQWELLSYHDGHRIPHLLISYLEERVRYAERWHGAVRDWPKPLGFVWGLAD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 PVATTNVLNGLR+LRP AAVVELPGLGHYPQ+E P+AYA AALSLLVD Sbjct 241 PVATTNVLNGLRDLRPHAAVVELPGLGHYPQLEDPRAYAGAALSLLVD 288 >gi|183982718|ref|YP_001851009.1| hydrolase [Mycobacterium marinum M] gi|183176044|gb|ACC41154.1| hydrolase [Mycobacterium marinum M] Length=288 Score = 486 bits (1250), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 237/287 (83%), Positives = 262/287 (92%), Gaps = 0/287 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSV +WR GG W+ TA GKVFVRSG G PT+LLLHG+PSSSFDFR+VIP+L GQAW Sbjct 1 MTSPSVSDWRAGGGWINTAAGKVFVRSGEGIAPTVLLLHGFPSSSFDFRSVIPYLAGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 +TMDFLGFGLSDKPRPHRYSLLEQA LV+ VVA VTG VVVLAHDMGTSVTTELLARDL Sbjct 61 LTMDFLGFGLSDKPRPHRYSLLEQADLVQNVVAQNVTGPVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 +GRLPF+L+RAVLSNGSVILERASLRPIQKVLR PLGP+AARLV+RGGFTRGFG++FS Sbjct 121 EGRLPFELQRAVLSNGSVILERASLRPIQKVLRGPLGPIAARLVNRGGFTRGFGKLFSAQ 180 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQEA+AQWELL +N+G+RI HLLISYL+ER R+AQRWH AVRDWPKPLGFVWGLDD Sbjct 181 HPLSAQEAEAQWELLTHNNGHRIAHLLISYLEERERYAQRWHNAVRDWPKPLGFVWGLDD 240 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLV 287 PVATTNVLNGLRELRP+A V+ELPGLGHYPQVE PKAY +AAL LLV Sbjct 241 PVATTNVLNGLRELRPNAGVIELPGLGHYPQVEDPKAYTQAALDLLV 287 >gi|118618441|ref|YP_906773.1| hydrolase [Mycobacterium ulcerans Agy99] gi|118570551|gb|ABL05302.1| hydrolase [Mycobacterium ulcerans Agy99] Length=310 Score = 472 bits (1215), Expect = 2e-131, Method: Compositional matrix adjust. Identities = 232/287 (81%), Positives = 258/287 (90%), Gaps = 0/287 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 VTSPSV +WR GG W+ TA GKVFVRSG G PT+LLLHG+PSSSF+FR+VIP+L GQAW Sbjct 23 VTSPSVSDWRAGGGWINTAAGKVFVRSGEGIAPTVLLLHGFPSSSFNFRSVIPYLAGQAW 82 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 +TMDFLGFGLSDKPRPHRYSLLEQA LV+ VVA VTG VVVLAHDMGTSVTTELLARDL Sbjct 83 LTMDFLGFGLSDKPRPHRYSLLEQADLVQNVVAQNVTGPVVVLAHDMGTSVTTELLARDL 142 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 +GRLPF+L+R VLSNGSVILERASLR IQKVLR PLGP+AARLV+RGGFTRGFG++FS Sbjct 143 EGRLPFELQRVVLSNGSVILERASLRLIQKVLRGPLGPIAARLVNRGGFTRGFGKLFSAQ 202 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 HPLSAQE +AQWELL +N+G+RI HLLISYL+ER R+AQRW+ AVRDWPKPLGFVWGLDD Sbjct 203 HPLSAQEPEAQWELLTHNNGHRIAHLLISYLEERERYAQRWNNAVRDWPKPLGFVWGLDD 262 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLV 287 PVATTNVLNGLRELRP+A V+ELPGLGHYPQVE PKAY + AL LLV Sbjct 263 PVATTNVLNGLRELRPNAGVIELPGLGHYPQVEDPKAYTQPALDLLV 309 >gi|333990578|ref|YP_004523192.1| hydrolase [Mycobacterium sp. JDM601] gi|333486547|gb|AEF35939.1| hydrolase [Mycobacterium sp. JDM601] Length=294 Score = 418 bits (1075), Expect = 5e-115, Method: Compositional matrix adjust. Identities = 206/282 (74%), Positives = 236/282 (84%), Gaps = 0/282 (0%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMD 64 SVR W+DGGRW+ + G+VFVRS GD PT+LLLHG+PS S+DF +V+ L G++W+TMD Sbjct 12 SVRRWQDGGRWVSSTAGRVFVRSDAGDGPTVLLLHGFPSCSYDFVSVVDRLAGRSWLTMD 71 Query 65 FLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRL 124 FLGFGLSDKP PHRYSL EQA LVE VVA + +G VV+ AHDMGTSV TELLARD+ G L Sbjct 72 FLGFGLSDKPNPHRYSLFEQADLVEQVVASSASGPVVLAAHDMGTSVATELLARDMAGTL 131 Query 125 PFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLS 184 FDLRRA LSNGSVILERASLRPIQKVLR P G +AARL +R F RGFGR+FS HPL+ Sbjct 132 SFDLRRAALSNGSVILERASLRPIQKVLRGPFGGLAARLTNRRSFARGFGRLFSADHPLA 191 Query 185 AQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVAT 244 A+EA AQW LL +N GNRI HLL +YLDER+RHAQRWHGAVRDWPKPLGFVW LDDPVAT Sbjct 192 AEEAAAQWALLTHNGGNRIAHLLSAYLDERVRHAQRWHGAVRDWPKPLGFVWALDDPVAT 251 Query 245 TNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 TNVL+GLRELRP+A V+ELPGLGHYPQ+E P+AY +A L LL Sbjct 252 TNVLDGLRELRPAADVIELPGLGHYPQIEDPQAYTDAVLRLL 293 >gi|289750406|ref|ZP_06509784.1| hydrolase [Mycobacterium tuberculosis T92] gi|289690993|gb|EFD58422.1| hydrolase [Mycobacterium tuberculosis T92] Length=207 Score = 285 bits (730), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 144/147 (98%), Positives = 145/147 (99%), Gaps = 0/147 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLA DL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLALDL 120 Query 121 DGRLPFDLRRAVLSNGSVILERASLRP 147 DGRLPFDLR AVLSNGSVILERASLRP Sbjct 121 DGRLPFDLRLAVLSNGSVILERASLRP 147 >gi|289761982|ref|ZP_06521360.1| hypothetical hydrolase [Mycobacterium tuberculosis GM 1503] gi|289709488|gb|EFD73504.1| hypothetical hydrolase [Mycobacterium tuberculosis GM 1503] Length=207 Score = 251 bits (640), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 122/124 (99%), Positives = 124/124 (100%), Gaps = 0/124 (0%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 +TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW Sbjct 1 MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL Sbjct 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 Query 121 DGRL 124 DGR+ Sbjct 121 DGRV 124 >gi|114564776|ref|YP_752290.1| alpha/beta hydrolase fold [Shewanella frigidimarina NCIMB 400] gi|114336069|gb|ABI73451.1| alpha/beta hydrolase fold [Shewanella frigidimarina NCIMB 400] Length=292 Score = 201 bits (511), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 107/280 (39%), Positives = 160/280 (58%), Gaps = 2/280 (0%) Query 8 EWRDGGRWLPTAVGKVFVR-SGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDF 65 EW+ G++L ++F R +G P +LL+HGYPS+S+D+ + LT +V T+D Sbjct 8 EWQQQGQFLSINDQQIFTRQAGDRKAPALLLIHGYPSASWDWEGMWHELTQHYFVVTLDM 67 Query 66 LGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLP 125 LGFG SDKP+ Y + +QA + E V+ +LAHD G +V ELLAR LDG Sbjct 68 LGFGFSDKPKNVDYLISQQADIYEAVLQQFGVSHYHILAHDYGDTVAQELLARQLDGNST 127 Query 126 FDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSA 185 + NG + E IQ +L SPLGP+ ++L+++ F RIF P+ P + Sbjct 128 LSINSVCFLNGGLFPETHKPLLIQTLLLSPLGPLVSKLINKQKFAVNLQRIFGPSTPPTP 187 Query 186 QEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATT 245 Q A W+LL +N+G + H LI+Y+ +R +H +RW GA+ + P+ + G+ DP++ Sbjct 188 QVIDALWQLLNHNNGLAVMHKLINYITQRKQHRERWVGAIINSTIPIKLIAGVKDPISGQ 247 Query 246 NVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSL 285 ++++ R+L P A V ELP LGHYPQVE A A L Sbjct 248 HMIDHYRKLIPHADVTELPTLGHYPQVEDANAIIAAYLQF 287 >gi|308047953|ref|YP_003911519.1| alpha/beta hydrolase fold protein [Ferrimonas balearica DSM 9799] gi|307630143|gb|ADN74445.1| alpha/beta hydrolase fold protein [Ferrimonas balearica DSM 9799] Length=293 Score = 189 bits (479), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 109/280 (39%), Positives = 158/280 (57%), Gaps = 3/280 (1%) Query 4 PSVREWRDGGRWLPTAVGKVFVRSGPG-DTPTMLLLHGYPSSSFDFRAVIPHLTGQ-AWV 61 P++ +W+ G +F R P P +LL+HG+PS+S+D+ A+ P L+ + Sbjct 10 PTLDQWQAAGATFHWRGHALFYRYQPNPGKPVLLLVHGFPSASWDWWALWPTLSQHYQLL 69 Query 62 TMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLD 121 + D LGFGLSDKP PHRY + +QA ++ ++A GA +LAHD G +VT ELLA+ L+ Sbjct 70 SADMLGFGLSDKPHPHRYCIADQARMLLDLMAELGLGAAHILAHDYGDTVTQELLAQQLE 129 Query 122 GRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAH 181 G L NG + E PIQ+++ P+GP+ ARL+ F RI+ Sbjct 130 GSTGVHWHSVTLLNGGLFPEAHRPLPIQRLMAGPVGPLLARLLGERRFKASLRRIWGETP 189 Query 182 PLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDP 241 P A E W+LLC G R+ LI Y+ ER +H RW A++ PL + GL DP Sbjct 190 PTEA-ELDTLWQLLCLKRGQRVIPGLIQYMAERRQHRTRWVDALQRTEGPLTLIDGLADP 248 Query 242 VATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEA 281 ++ +++ R+L P VV LPG+GHYPQ+EAP+A EA Sbjct 249 ISGQTLVDRFRQLCPHGRVVTLPGVGHYPQLEAPQAVLEA 288 >gi|239994052|ref|ZP_04714576.1| alpha/beta hydrolase fold protein [Alteromonas macleodii ATCC 27126] Length=287 Score = 187 bits (475), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 100/283 (36%), Positives = 161/283 (57%), Gaps = 3/283 (1%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQ-AWVTM 63 + +WR G +L +VF ++ G P +LL+HGYP++SFD+ + P LT Q VT+ Sbjct 2 QLSQWRSSGHFLNVDGQQVFYKT-EGTGPVLLLVHGYPTASFDWAKIWPALTSQFRCVTL 60 Query 64 DFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGR 123 D GFG SDK P +Y + EQA + V+ H + VL+HD G +V E++AR L+ Sbjct 61 DMPGFGFSDKS-PKKYLIKEQADTISEVIRHLGITSAHVLSHDYGDTVAQEMMARQLEDD 119 Query 124 LPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPL 183 L F + L NG + E PIQK+L SP+G + R +++ + IF P P Sbjct 120 LAFRIESLHLLNGGLFPETHRALPIQKLLLSPIGGLLIRFLNKNAIRKSMHNIFGPNTPP 179 Query 184 SAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVA 243 S Q+ W L+ N+G++ HLL+ Y+ +R ++ +RW A+++ PL G+ DP++ Sbjct 180 SDQDINDFWILISTNNGHQHMHLLLDYMKQRKQYRERWVSALQNANAPLRLTAGMADPIS 239 Query 244 TTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 +++ ++L P+A V+EL +GHYPQ+E+ +A + S L Sbjct 240 GAHMVARYKQLIPNADVIELDQIGHYPQIESAEAVVNSIASFL 282 >gi|149376888|ref|ZP_01894643.1| alpha/beta hydrolase fold protein [Marinobacter algicola DG893] gi|149358780|gb|EDM47249.1| alpha/beta hydrolase fold protein [Marinobacter algicola DG893] Length=304 Score = 187 bits (474), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 109/274 (40%), Positives = 158/274 (58%), Gaps = 4/274 (1%) Query 3 SPSVREWRDGGRWLPTAVGKVFVR-SGPGDTPTMLLLHGYPSSSFDFRAVIPHL-TGQAW 60 + ++ W+ G+W VF R +G GD ++LLHG+P++S+D+ + P L Sbjct 17 NATLEWWQQEGKWFSYGGHAVFSRMAGQGDP--VVLLHGFPTASWDWSRLWPMLLQHHTL 74 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 T+D LGFG SDKP + YS+ +QA + E +A V + AHD G SV ELLARD Sbjct 75 FTLDMLGFGFSDKPSLYDYSIEDQADMFEGWIAGLGLKKVSLFAHDYGGSVAQELLARDQ 134 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 +G LPF + R NG++ E S IQK+L SPLG + +R ++R F R F R+F P Sbjct 135 EGLLPFSITRVGFLNGALFPEVHSPLLIQKLLGSPLGGLISRGLTRRTFERNFRRLFGPE 194 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 +P S ++ W LL YN+G I H LI +++ER H RW GA++ +P+ + G+ D Sbjct 195 NPPSRKDMDDFWYLLTYNNGRGILHNLIHFMEERRCHRNRWVGALQKAEQPMRLISGVVD 254 Query 241 PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEA 274 PV+ + + REL P+A VV L +GHYP E Sbjct 255 PVSGSAMARRYRELVPNADVVSLRNVGHYPHFET 288 >gi|329935911|ref|ZP_08285713.1| putative epoxide hydrolase [Streptomyces griseoaurantiacus M045] gi|329304602|gb|EGG48478.1| putative epoxide hydrolase [Streptomyces griseoaurantiacus M045] Length=279 Score = 183 bits (465), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 114/282 (41%), Positives = 155/282 (55%), Gaps = 10/282 (3%) Query 8 EWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLT--GQAWVTMDF 65 +W GG + ++FVR G+ + LLHG+P+SS D+ +P L G ++D Sbjct 5 DWIAGGERVELDGHRLFVRQD-GEGRPVTLLHGFPTSSHDWAWTVPSLVAAGCRVTSLDL 63 Query 66 LGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLP 125 LGFG SDKPR HRYS+ EQA LVE + TG +++AHD G SV ELLARD P Sbjct 64 LGFGHSDKPRGHRYSIHEQADLVEALWGRLGTGPTMLVAHDYGVSVAQELLARD-----P 118 Query 126 FDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSA 185 L R L NG + + P+Q++L SPLGP+ ARL F G + S P+ Sbjct 119 GRLTRTALLNGGLYGDLHRPVPVQRLLHSPLGPLFARLTDEKRFVAGLRGVLS--RPVPD 176 Query 186 QEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATT 245 + W + +G + L+ Y+D+R H RW ++ + PL FVWG +DPV+ Sbjct 177 EVLHDMWTAADHENGRLLAPRLLRYIDDRRVHFDRWSASLERYEGPLLFVWGPEDPVSGA 236 Query 246 NVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLV 287 +VL LRE RP A LPG+GHYPQVEAP+ A A + L Sbjct 237 HVLPRLRERRPEATFTVLPGVGHYPQVEAPEETAGALSAFLT 278 >gi|241603782|ref|XP_002405756.1| soluble epoxide hydrolase, putative [Ixodes scapularis] gi|215502567|gb|EEC12061.1| soluble epoxide hydrolase, putative [Ixodes scapularis] Length=339 Score = 183 bits (464), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 113/293 (39%), Positives = 164/293 (56%), Gaps = 9/293 (3%) Query 3 SPSVREWR--DGGRWLPTAVGKVFVR--SGPGDTPTMLL-LHGYPSSSFDFRAVIPHLTG 57 SP + +W DGG + ++F + +G D+ +LL LHG+P+SSFDF ++P L Sbjct 28 SPLLYQWEKNDGGSYFIADNYEIFYKDVTGSADSEDILLCLHGFPTSSFDFYLMLPSLRK 87 Query 58 --QAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTEL 115 V +DFLG G SDKPR H YS+ EQA++ E +VA V +LAHD+G +V EL Sbjct 88 IFGRIVFLDFLGLGYSDKPRFHTYSIFEQANITEALVARLRLRRVHILAHDLGDTVAQEL 147 Query 116 LARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSP-LGPVAARLVSRGGFTRGFG 174 LAR +G LPF ++ L NG V+ + R QK+LR+P +G VA+RL++ F Sbjct 148 LARQNEGSLPFQIKTLCLLNGGVLPKHHYPRWSQKLLRTPVVGVVASRLMNHLAFRVALS 207 Query 175 RIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGF 234 +F P +A + W L DG R+ L++SY+DER H RW GA++ P+ Sbjct 208 DVFGPNTKPTATDIHNYWHLARLKDGYRVFGLILSYIDERAEHEDRWVGALQKSAAPVHM 267 Query 235 VWGLDDPVATTNVLNGLRELRPSAAVVELPG-LGHYPQVEAPKAYAEAALSLL 286 ++G DPV R+ PS+++ LP +GHY Q+EAP+ A L L Sbjct 268 IYGPADPVNPPPFQEHYRKEVPSSSIHVLPEHVGHYVQLEAPQEVIAAYLPFL 320 >gi|24216487|ref|NP_713968.1| putative hydrolase [Leptospira interrogans serovar Lai str. 56601] gi|45656356|ref|YP_000442.1| hypothetical protein LIC10458 [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130] gi|24197793|gb|AAN50986.1| putative hydrolase [Leptospira interrogans serovar Lai str. 56601] gi|45599590|gb|AAS69079.1| conserved hypothetical protein [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130] Length=283 Score = 183 bits (464), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 96/284 (34%), Positives = 161/284 (57%), Gaps = 7/284 (2%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVI-PHLTGQAWVTM 63 ++ +W+ G + K+F++ G +LL+HG+P++SFD+ + P + + + Sbjct 2 NLEKWKQSGEYFSYQNWKIFLKE-EGKGENILLIHGFPTASFDWEKIWRPLSKNRRVIAL 60 Query 64 DFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLD-- 121 D LGFG S KP+ YS+ QA ++E +++ +LAHD+G +VT ELLAR +D Sbjct 61 DMLGFGFSSKPKID-YSIFLQADIIEKLLSDKGILETKILAHDLGDTVTQELLARFIDRK 119 Query 122 --GRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSP 179 G+ +++ L NG + E + IQK+L SPLG + + ++R F + F +F Sbjct 120 NSGKKGLNIQAITLLNGGIFPESHRPKFIQKLLHSPLGWILSEFMNRKSFQKSFSSVFGV 179 Query 180 AHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLD 239 S +E WEL+ ++ G +I + LI Y+ ER + RW + + P P+ + G++ Sbjct 180 NTKPSLEELDQFWELVSFDGGEKIAYKLIRYIQERKINRSRWVNVLLNSPIPIRMINGIE 239 Query 240 DPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAAL 283 DP++ TN++ +EL PSA +VEL +GHYPQVEAP ++ L Sbjct 240 DPISGTNIVKRYKELVPSADIVELLRIGHYPQVEAPDQVLKSIL 283 >gi|120556686|ref|YP_961037.1| alpha/beta hydrolase fold [Marinobacter aquaeolei VT8] gi|120326535|gb|ABM20850.1| alpha/beta hydrolase fold protein [Marinobacter aquaeolei VT8] Length=295 Score = 182 bits (463), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 103/272 (38%), Positives = 150/272 (56%), Gaps = 2/272 (0%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQ-AWVTM 63 ++ W+ G+W +F R G G ++LLHG+P++S+D+ + P L + +T+ Sbjct 11 TLEAWQQAGKWFSYEGHAIFSRMG-GQGEPLVLLHGFPTASWDWSRIWPMLVREHNLLTL 69 Query 64 DFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGR 123 D LGFG SDKP + YS+ +QA L++ + V + HD GT+V ELLAR+ +G Sbjct 70 DMLGFGFSDKPLHYSYSIEDQADLIQGWIEGLGLERVHLFGHDYGTTVVQELLAREQEGE 129 Query 124 LPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPL 183 L F + L NG + E IQK+LRSPLG + R +SR F R F R+F +P Sbjct 130 LSFAISSVCLLNGGLFPEVHHPLFIQKILRSPLGGLIGRGLSRSLFERNFRRLFGSRNPP 189 Query 184 SAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVA 243 Q+ W LL YN+G + H LI +++ER H RW GA++ +P+ + G DPV+ Sbjct 190 GRQDMDDFWHLLNYNNGRGVLHRLIQFMEERRCHRNRWVGALQKAEQPMRLISGGADPVS 249 Query 244 TTNVLNGLRELRPSAAVVELPGLGHYPQVEAP 275 + REL P A VV L +GHYP E P Sbjct 250 GAAMARRYRELIPQADVVMLRNVGHYPHFEQP 281 >gi|311744126|ref|ZP_07717932.1| hydrolase [Aeromicrobium marinum DSM 15272] gi|311313256|gb|EFQ83167.1| hydrolase [Aeromicrobium marinum DSM 15272] Length=293 Score = 182 bits (463), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 117/281 (42%), Positives = 155/281 (56%), Gaps = 9/281 (3%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVT 62 S V WRD GR+L ++FV PGD T+L+LHGYP SS DF V+ L+ V Sbjct 7 SDRVTAWRDAGRYLELGGHRIFVHEQPGDGTTVLVLHGYPGSSHDFAEVVGRLSAPV-VA 65 Query 63 MDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDG 122 D LG+G SDKP YSL EQA LVE V V++AHDMGT+V ELLAR +G Sbjct 66 PDLLGYGFSDKPTRATYSLFEQADLVEQVAREVGVQRCVLVAHDMGTTVAAELLARHHEG 125 Query 123 RLPFDLRRAVLSNGSVILERASLRPIQKV---LRSPLGPVAARLVSRGGFT-RGFGRIFS 178 RL FD+ + VL+NGS+ ++ A L Q+ LRS L VA G F R + Sbjct 126 RLSFDVDQVVLTNGSIFIDLARLTRGQRAGLRLRSWLPAVAL----PGAFVRRSLRESIA 181 Query 179 PAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGL 238 P + A++ L+ G R+ + YL+ER RH RW + D+P P+ WGL Sbjct 182 PGTDVGAEDLADLLGLIGRGGGRRVLLRQLVYLEERRRHQARWTAGLVDFPGPVTAAWGL 241 Query 239 DDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYA 279 DP+A +++ L ELRP+ VV P +GH+P +EAP A Sbjct 242 RDPIAIPAMVDRLGELRPATTVVSWPDVGHWPSLEAPDRLA 282 >gi|332535392|ref|ZP_08411183.1| hydrolase, alpha/beta fold family [Pseudoalteromonas haloplanktis ANT/505] gi|332035185|gb|EGI71695.1| hydrolase, alpha/beta fold family [Pseudoalteromonas haloplanktis ANT/505] Length=289 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 102/283 (37%), Positives = 157/283 (56%), Gaps = 2/283 (0%) Query 5 SVREWRDGGRWLPTAVGKVFVR-SGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-T 62 S+++W+ G++ + ++F + +G P +LL+HG+PS+S+D+ + L+ +V T Sbjct 3 SLQQWQSQGQFTHISGHQIFTKIAGDITKPALLLIHGFPSASWDWEGMWQTLSEYYFVIT 62 Query 63 MDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDG 122 +D LGFGLSDKP Y + EQA L + V +LAHD G +V ELLAR + Sbjct 63 LDMLGFGLSDKPINATYKITEQADLYTQFLKTLNINDVHILAHDYGDTVAQELLARQVVS 122 Query 123 RLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHP 182 + F + NG + E IQK+L S LG + +L+++ F IF + P Sbjct 123 QSDFKINSVCFLNGGLFPEVHKPLFIQKLLLSKLGWIVPKLMNKQKFANNLLTIFGKSTP 182 Query 183 LSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPV 242 S Q WELL Y DG + LISY+ +R ++ +RW GA+ + PL F+ G +DP+ Sbjct 183 PSKQVVDTLWELLIYKDGLAVMPKLISYIKQRQQNRERWVGAIINSNIPLTFIAGAEDPI 242 Query 243 ATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSL 285 + +++ ++L P+A V EL LGHYPQVE P A +A L Sbjct 243 SGKHMIEHYKKLAPNARVQELVELGHYPQVENPDAITQAYLDF 285 >gi|149922586|ref|ZP_01911015.1| probable epoxide hydrolase [Plesiocystis pacifica SIR-1] gi|149816542|gb|EDM76038.1| probable epoxide hydrolase [Plesiocystis pacifica SIR-1] Length=312 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 119/296 (41%), Positives = 159/296 (54%), Gaps = 19/296 (6%) Query 5 SVREWRDGGRWLPTAVGKVFV-RSGPGDTP------TMLLLHGYPSSSFDFRAVIPHLTG 57 S +WR G ++FV SGP P ++L+HG+P++S+D+ + L Sbjct 3 STADWRGRGVERAYLGHRIFVVDSGPPPNPAAGADSVVVLIHGFPTASWDWAPIWDALAS 62 Query 58 Q-AWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVV-----AHTVTGAVVVLAHDMGTSV 111 + + +D LGFG S KPR H YS+LEQA LVE ++ + V VLAHD G +V Sbjct 63 EHRLLALDLLGFGFSAKPRGHGYSILEQADLVEALIRDRLAPEALDRGVHVLAHDYGDTV 122 Query 112 TTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTR 171 ELLAR G L +R L NG + E R IQK+L SPLGP+ +RL ++ F R Sbjct 123 AQELLARHDAGHLAAPMRSLALLNGGLFPETHQARIIQKLLLSPLGPLVSRLTTKASFGR 182 Query 172 GFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKP 231 F R+F P SA E A W L+ G HLLI Y+ ERI H RW GA+ D P Sbjct 183 AFARVFGPDTQPSAAEIDAFWSLIDLERGQLNSHLLIRYMPERIEHRARWVGALVDAQLP 242 Query 232 LGFVWGLDDPVATTNVLNGLREL--RPSAA----VVELPGLGHYPQVEAPKAYAEA 281 + + G DPV+ +++ REL P AA +VELP +GHYPQVE P+ A Sbjct 243 IAIINGSVDPVSGAHMVARYRELLAEPIAAGRDTIVELPRIGHYPQVEDPEGVLSA 298 >gi|311696419|gb|ADP99292.1| mesoderm specific transcript isoform b isoform-like protein [Marinobacter adhaerens HP15] Length=355 Score = 179 bits (455), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 100/272 (37%), Positives = 150/272 (56%), Gaps = 2/272 (0%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TM 63 ++ W+ GG+W +F R P ++L+HG+P++S+D+ + P L Q V + Sbjct 69 TLEGWQHGGKWFSFEGHAIFSRMAGSGEP-LVLIHGFPTASWDWNRLWPMLIQQHNVLAL 127 Query 64 DFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGR 123 D LGFG SDKP + YS+ +QA L + + +V +L HD G SV ELLAR+ + Sbjct 128 DMLGFGFSDKPADYDYSIEDQADLFQGWIEGLGLPSVHLLVHDYGCSVAQELLAREQEDL 187 Query 124 LPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPL 183 LPF + NG++ E + IQK+L SP G + +R ++R F R F R+F +P Sbjct 188 LPFRIASVCFLNGALFPEVHNPLLIQKLLGSPFGGLISRGLTRRSFERNFRRLFGSQNPP 247 Query 184 SAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVA 243 Q+ + W LL YN+G I H LI +++ER H RW GA++ +P+ + G DPV+ Sbjct 248 DRQDMEDFWHLLTYNNGRGILHHLIQFMEERRCHRNRWVGALQKATQPMRLISGTADPVS 307 Query 244 TTNVLNGLRELRPSAAVVELPGLGHYPQVEAP 275 + REL P VV L +GHYP +E P Sbjct 308 GAGMARRYRELMPDGDVVTLRNIGHYPHLECP 339 >gi|254447121|ref|ZP_05060588.1| hydrolase, alpha/beta fold family [gamma proteobacterium HTCC5015] gi|198263260|gb|EDY87538.1| hydrolase, alpha/beta fold family [gamma proteobacterium HTCC5015] Length=301 Score = 173 bits (438), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 97/285 (35%), Positives = 146/285 (52%), Gaps = 2/285 (0%) Query 5 SVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTM- 63 + W + G +FVR TP +LLLHG+PS S+D+ + P L + + M Sbjct 3 EINSWHEDGAGHTILGHNIFVREQGKGTP-LLLLHGFPSCSWDWHKIAPKLEKEFRLIMP 61 Query 64 DFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGR 123 DFLG G SDKPR H Y++ EQ ++E ++ VLAHD G SV ELLAR + R Sbjct 62 DFLGMGFSDKPRSHDYTIFEQTDIIEHLMDELGIRECSVLAHDYGDSVLQELLARQQEAR 121 Query 124 LPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPL 183 L F ++RA++ NG + E + P Q+ L PLG V + + + I +P Sbjct 122 LGFRIQRALMLNGGLFPEAHNPLPTQRWLAGPLGGVIGVYLQKAHLAKAMQAIAGVENPP 181 Query 184 SAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVA 243 A ++ W + +N G R+ H + Y+ ER QRW A+ PL + G DP++ Sbjct 182 DANTIESWWASIQHNKGKRVMHRIAGYMAERETQQQRWSDALAHANIPLAMINGTLDPIS 241 Query 244 TTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD 288 + ++ + P+ +V LP +GHYPQ+EAP A A+ A + Sbjct 242 GSEMVKVYERVVPNPRIVRLPTVGHYPQIEAPDAVAKLASQFFSN 286 >gi|221134787|ref|ZP_03561090.1| alpha/beta hydrolase fold protein [Glaciecola sp. HTCC2999] Length=306 Score = 170 bits (431), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 97/255 (39%), Positives = 145/255 (57%), Gaps = 9/255 (3%) Query 33 PTMLLLHGYPSSSFDFRAVIPHLTGQAW-VTMDFLGFGLSDKPRPHRYSLLEQAHLVETV 91 P ++ LHG+PS+S D++A L + + +DFLGFG+SDKP PH+YSL EQA +VE + Sbjct 44 PVVVFLHGFPSASSDWKAQWHTLKDTHFCIGLDFLGFGISDKPYPHQYSLHEQADIVELL 103 Query 92 VAHTVTGAVV---VLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPI 148 A + + ++AHD G SV ELLAR RL ++ V NG + A +PI Sbjct 104 FARLIERGITKIHLVAHDYGVSVAQELLARQQQQRLALNISSVVFMNGGLF--AALHKPI 161 Query 149 --QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHL 206 QK+L+SP+G + ++ +S+ F +IF P P + W+LL + G R+ Sbjct 162 WTQKLLKSPIGGLLSKFMSKRTLASSFNQIFGPKTPPQPELIDELWQLLNVHQGRRVIPQ 221 Query 207 LISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGL 266 L+SY+DER +A RW A+ PL + G+ DP++ ++LN L P L + Sbjct 222 LLSYIDERYANATRWQDALTQAKIPLTLINGVHDPISGQHMLNEFERLLPQTHNTPL-NV 280 Query 267 GHYPQVEAPKAYAEA 281 GHYPQ+EAP+A +A Sbjct 281 GHYPQIEAPEAVTQA 295 >gi|254480063|ref|ZP_05093311.1| hydrolase, alpha/beta fold family, putative [marine gamma proteobacterium HTCC2148] gi|214039625|gb|EEB80284.1| hydrolase, alpha/beta fold family, putative [marine gamma proteobacterium HTCC2148] Length=300 Score = 170 bits (430), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 102/287 (36%), Positives = 152/287 (53%), Gaps = 3/287 (1%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPGDTP-TMLLLHGYPSSSFDFRAVIPHLTGQA-W 60 S +V+ W D G ++FV + T++L+HG+P+S+FDF + L Q Sbjct 10 SKAVQTWFDRGSMRSINGNEIFVVDHRHENKSTIVLIHGFPTSTFDFDLIWQALGKQHRL 69 Query 61 VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL 120 V +D LGFG SDKP Y+L +QA L + +++ VLAHD G SV ELLAR + Sbjct 70 VCLDMLGFGFSDKPNKRDYTLHKQADLFDRLISDLGIDEYHVLAHDYGDSVAQELLARQI 129 Query 121 DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA 180 +G NG + E IQK++ SPLG +A +L F F ++F A Sbjct 130 EGTGQGKWLSGCFLNGGLFPETHKALLIQKIMLSPLGKLANKLTGFKAFGTSFSKVFGDA 189 Query 181 HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD 240 S E WE++ Y G I H L++Y+ +R H RW A+++ P P+ + G D Sbjct 190 TKPSDAELGEFWEIINYKGGRHIFHNLMTYILDRREHRSRWLDALQNSPVPICVINGSVD 249 Query 241 PVATTNVLNGLRELRPS-AAVVELPGLGHYPQVEAPKAYAEAALSLL 286 PV+ +++ ++L +VELP +GHYPQVEAP+ +EA L+ L Sbjct 250 PVSGKHLVARYQQLNCRLDQLVELPRIGHYPQVEAPQQVSEAYLAFL 296 >gi|332305363|ref|YP_004433214.1| alpha/beta hydrolase fold protein [Glaciecola agarilytica 4H-3-7+YE-5] gi|332172692|gb|AEE21946.1| alpha/beta hydrolase fold protein [Glaciecola sp. 4H-3-7+YE-5] Length=297 Score = 169 bits (429), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 101/252 (41%), Positives = 141/252 (56%), Gaps = 10/252 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW--VTMDFLGFGLSDKPRPHRYSLLEQAHL 87 D P +LL+HG+PS+++D+ H+ Q + V +D LGFGLSDKP H YSLLEQA + Sbjct 37 NDEPWVLLIHGFPSAAWDWHNQW-HVLRQKYRLVCLDLLGFGLSDKPNKHDYSLLEQADI 95 Query 88 VETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 +E ++A +LAHD G SV ELL R + R ++ NG + + RP Sbjct 96 LEVLLAKLHIKRCHILAHDYGDSVAQELLTRHAEKRSNLSIQSVCYLNGGLFAD--CHRP 153 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRI-P 204 + QK+L+SPLGP AR +S+ R F +IF P A + LL + G R+ P Sbjct 154 LLTQKLLKSPLGPFMARFMSQSSLHRSFAKIFGPNSQPDAAHIAILYALLEWKQGKRVLP 213 Query 205 HLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELP 264 HLL Y+DER A RW A++ P F+ G+ DP++ ++LN L P A L Sbjct 214 HLL-KYIDERKAQASRWINAMQHTTVPQCFINGVHDPISGQHMLNQFEHLLPHAQTYAL- 271 Query 265 GLGHYPQVEAPK 276 +GHYPQ+EAPK Sbjct 272 QVGHYPQLEAPK 283 >gi|85374314|ref|YP_458376.1| epoxide hydrolase [Erythrobacter litoralis HTCC2594] gi|84787397|gb|ABC63579.1| probable epoxide hydrolase [Erythrobacter litoralis HTCC2594] Length=289 Score = 168 bits (425), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 106/289 (37%), Positives = 148/289 (52%), Gaps = 3/289 (1%) Query 1 VTSPSVREWRDGGRWLP-TAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 + PS+ EW+ + + F G D +LL+HGYP++S+D+ V L + Sbjct 1 MAGPSLGEWKAKAQHFAYDGLQIAFWTGGKPDARPLLLVHGYPTASWDWHRVWETLGSKY 60 Query 60 -WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLAR 118 V D +GFGLSDKPR YS+ QA + ++ H GA L HD G SV ELLAR Sbjct 61 HLVAPDMIGFGLSDKPRS-GYSIHRQADMHVALLDHLGIGAFDALVHDYGVSVGQELLAR 119 Query 119 DLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFS 178 + L + V NG + ++ RPIQK+ SPLG + L +R F R F +F Sbjct 120 RAERSAAQGLGQTVFLNGGIFPDQHRPRPIQKLGTSPLGFLVGLLTNREKFGRSFSEVFG 179 Query 179 PAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGL 238 P AQE W+L+ +N GNRI H L+ Y+ +R HA+RW A+R +G + G Sbjct 180 PDTQPGAQELDEFWDLVSHNGGNRIMHKLLHYIADRKEHAERWFDALRIAQGDIGLINGA 239 Query 239 DDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLV 287 DPV+ + RE P A +P +GHYPQVE P+ + L L Sbjct 240 LDPVSGRHAYEAWRERLPDARHHLIPTVGHYPQVEDPQTVSRVTLDWLA 288 >gi|94734200|emb|CAK04921.1| mesoderm specific transcript [Danio rerio] Length=343 Score = 166 bits (421), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 103/297 (35%), Positives = 161/297 (55%), Gaps = 14/297 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 SP++ WR G + +F + G + ++LLHG+P+SS+D+ + LT + Sbjct 45 SPALNSWRTSGHFFTFRGNDIFYKESVGVVGSSDVLVLLHGFPTSSYDWYKIWDSLTQRF 104 Query 60 --WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGA--VVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPHRYS+ EQA +VE +VAH + +L+HD G +V EL Sbjct 105 NRVIALDFLGFGFSDKPRPHRYSIFEQASVVEALVAHLGLSEQRINILSHDYGDTVALEL 164 Query 116 LARDLDGRLPFDLRRAV-LSNGSVILERASLRPIQKVLRSP--LGPVAARLVSRGGFTRG 172 L R R + ++ LSNG + E R +QKVL+ + PV RL++ F+RG Sbjct 165 LYRSDHNRSGHIIVNSLCLSNGGIFPETHHPRFLQKVLKDSGFISPVLTRLMNFQLFSRG 224 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 +F P + E W + +NDGN + L+ Y+++R++H +RW GA+ PL Sbjct 225 IKEVFGPYTQPTEAEVWDMWTGIRFNDGNLVMDSLLQYINQRLKHRERWVGALTSTLTPL 284 Query 233 GFVWGLDDPVA-TTNVLNGLREL--RPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L ++L R + +V++ + HYPQ+E P + A LS + Sbjct 285 HMIYGPLDPVNPHPQFLQLYQKLVQRSTVSVLD-EHVSHYPQLEDPTGFFNAYLSFI 340 >gi|94734201|emb|CAK04922.1| mesoderm specific transcript [Danio rerio] Length=344 Score = 166 bits (421), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 103/297 (35%), Positives = 161/297 (55%), Gaps = 14/297 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 SP++ WR G + +F + G + ++LLHG+P+SS+D+ + LT + Sbjct 46 SPALNSWRTSGHFFTFRGNDIFYKESVGVVGSSDVLVLLHGFPTSSYDWYKIWDSLTQRF 105 Query 60 --WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGA--VVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPHRYS+ EQA +VE +VAH + +L+HD G +V EL Sbjct 106 NRVIALDFLGFGFSDKPRPHRYSIFEQASVVEALVAHLGLSEQRINILSHDYGDTVALEL 165 Query 116 LARDLDGRLPFDLRRAV-LSNGSVILERASLRPIQKVLRSP--LGPVAARLVSRGGFTRG 172 L R R + ++ LSNG + E R +QKVL+ + PV RL++ F+RG Sbjct 166 LYRSDHNRSGHIIVNSLCLSNGGIFPETHHPRFLQKVLKDSGFISPVLTRLMNFQLFSRG 225 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 +F P + E W + +NDGN + L+ Y+++R++H +RW GA+ PL Sbjct 226 IKEVFGPYTQPTEAEVWDMWTGIRFNDGNLVMDSLLQYINQRLKHRERWVGALTSTLTPL 285 Query 233 GFVWGLDDPVA-TTNVLNGLREL--RPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L ++L R + +V++ + HYPQ+E P + A LS + Sbjct 286 HMIYGPLDPVNPHPQFLQLYQKLVQRSTVSVLD-EHVSHYPQLEDPTGFFNAYLSFI 341 >gi|149927157|ref|ZP_01915414.1| probable epoxide hydrolase [Limnobacter sp. MED105] gi|149824096|gb|EDM83317.1| probable epoxide hydrolase [Limnobacter sp. MED105] Length=286 Score = 166 bits (421), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 87/267 (33%), Positives = 142/267 (54%), Gaps = 4/267 (1%) Query 9 WRDGGRWLPTAVGKVFVR-SGPGDTPTMLLLHGYPSSSFDFRAVIPHLT-GQAWVTMDFL 66 W++ G++ +FV+ + + P +LL+HG+P++S+DF + P L + D L Sbjct 6 WKNSGQFFDWEGHSIFVQDTAASNKPVLLLIHGFPTASYDFHLLWPDLAETHRLIAFDML 65 Query 67 GFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPF 126 G+G SDKPR ++S+ QA + E ++ ++ HD+G +V ELLAR +G+L F Sbjct 66 GYGYSDKPRTWQHSIFNQADIAEALLKSKGVDECTMITHDVGDTVGQELLARHAEGKLGF 125 Query 127 DLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQ 186 L+R V+ NG + E +QK+L SP G V R + + + + S LS Sbjct 126 RLKRVVMLNGGLFPETHRAILVQKLLLSPFGFVFTRFMKKEKLSASLRSVCSAG--LSDA 183 Query 187 EAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTN 246 + A W L+ + GN HLLI Y+ ER + RW A++ P + G++DP++ + Sbjct 184 DIDAAWTLMAHKKGNLCMHLLIQYMRERRENRDRWVEALQKADMPFALIDGVEDPISGEH 243 Query 247 VLNGLRELRPSAAVVELPGLGHYPQVE 273 ++ EL P + L GLGHYP +E Sbjct 244 MVQRFEELVPGKQTIRLAGLGHYPHLE 270 >gi|7768535|dbj|BAA95444.1| alpha/beta hydroxylase [Danio rerio] Length=344 Score = 166 bits (421), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 103/297 (35%), Positives = 161/297 (55%), Gaps = 14/297 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 SP++ WR G + +F + G + ++LLHG+P+SS+D+ + LT + Sbjct 46 SPALNSWRTSGHFFTFRGNDIFYKESVGVVGSSDVLVLLHGFPTSSYDWYKIWDSLTQRF 105 Query 60 --WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGA--VVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPHRYS+ EQA +VE +VAH + +L+HD G +V EL Sbjct 106 NRVIALDFLGFGFSDKPRPHRYSIFEQASVVEALVAHLGLSEQRINILSHDYGDTVALEL 165 Query 116 LARDLDGRLPFDLRRAV-LSNGSVILERASLRPIQKVLRSP--LGPVAARLVSRGGFTRG 172 L R R + ++ LSNG + E R +QKVL+ + PV RL++ F+RG Sbjct 166 LYRSDHNRSGHIIVNSLCLSNGGIFPETHYPRFLQKVLKDSGFISPVLTRLMNFQLFSRG 225 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 +F P + E W + +NDGN + L+ Y+++R++H +RW GA+ PL Sbjct 226 IKEVFGPYTQPTEAEVWDMWTGIRFNDGNLVMDSLLQYINQRLKHRERWVGALTSTLTPL 285 Query 233 GFVWGLDDPVA-TTNVLNGLREL--RPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L ++L R + +V++ + HYPQ+E P + A LS + Sbjct 286 HMIYGPLDPVNPHPQFLQLYQKLVQRSTVSVLD-EHVSHYPQLEDPTGFFNAYLSFI 341 >gi|342861846|ref|ZP_08718491.1| hydrolase [Mycobacterium colombiense CECT 3035] gi|342130663|gb|EGT83967.1| hydrolase [Mycobacterium colombiense CECT 3035] Length=282 Score = 165 bits (418), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 110/288 (39%), Positives = 149/288 (52%), Gaps = 22/288 (7%) Query 5 SVREWRDGGRWLPTAVGK--VFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLT-GQAWV 61 S +W D L G F R G G PT+LLLHG+P+ S+D+ A+ L + Sbjct 3 SAAQWIDENETLTIRRGHRIAFRRRGTG--PTVLLLHGFPTWSYDYAALAGDLARDHHVI 60 Query 62 TMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLD 121 TMDFLG+G SDKP P+ YS+ E A VE + AH V ++ HD G V EL R Sbjct 61 TMDFLGYGASDKPNPYEYSVAESADTVEDLAAHLRVDPVSLVVHDYGGIVGQELADRANR 120 Query 122 GRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVS--------RGGFTRGF 173 GRL F + R V+ N ++ +QK+L L PV +L++ R G Sbjct 121 GRLGFTIDRLVVLNSGIVYSAYRPTRLQKLL---LLPVVGKLLAGRVDAARARSGLEGVR 177 Query 174 GRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLG 233 G F+ E + W + ++G+++ HLLI Y ER H +RW A+ W PL Sbjct 178 GSRFTDT------EFEDLWLGMSRDNGHKLAHLLIKYNAERAIHHRRWEAALAHWDGPLH 231 Query 234 FVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEA 281 VWGLDDPV+ +VL ++ P A V ELPG+GHYPQ EA + A A Sbjct 232 LVWGLDDPVSGRHVLEQAVKVLPHATVTELPGVGHYPQSEAAPSVAAA 279 >gi|90415661|ref|ZP_01223595.1| hydrolase, alpha/beta fold family protein [marine gamma proteobacterium HTCC2207] gi|90332984|gb|EAS48154.1| hydrolase, alpha/beta fold family protein [marine gamma proteobacterium HTCC2207] Length=313 Score = 164 bits (415), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 93/248 (38%), Positives = 138/248 (56%), Gaps = 4/248 (1%) Query 31 DTPTMLLLHGYPSSSFDFRAVIPHLTGQAW--VTMDFLGFGLSDKPRPHRYSLLEQAHLV 88 + PT++LLHG+P+SS+D++ I HL + + + +D LGFG SDKP H+YS+ QA L+ Sbjct 50 ELPTIILLHGFPTSSWDWQP-IWHLLAKDFRLIAVDMLGFGFSDKPSKHKYSIHGQADLI 108 Query 89 ETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPI 148 E +V VL HD G +V ELL+R L+G + NG + E Sbjct 109 EALVKAKQLQQFHVLTHDYGDTVGQELLSRQLEGSGAGEWLSCCFLNGGLFPETHRALLT 168 Query 149 QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLI 208 QK+L SP+G + R F R F +F S ++ + W L+ +NDG I H LI Sbjct 169 QKLLLSPIGSLLNRFTGYAKFCRNFSSVFGAQSKPSEEQLENFWWLINHNDGKHIFHNLI 228 Query 209 SYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPS-AAVVELPGLG 267 +Y+ +R+ H +RW A++ PLG + G DPV+ +++ +EL + ELP +G Sbjct 229 TYIRDRLEHRERWVSAMQQSTIPLGLINGSVDPVSGKHMVARYQELNCRLDYLAELPEIG 288 Query 268 HYPQVEAP 275 HYPQVEAP Sbjct 289 HYPQVEAP 296 >gi|330504493|ref|YP_004381362.1| alpha/beta hydrolase fold protein [Pseudomonas mendocina NK-01] gi|328918779|gb|AEB59610.1| alpha/beta hydrolase fold protein [Pseudomonas mendocina NK-01] Length=297 Score = 164 bits (415), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 114/284 (41%), Positives = 154/284 (55%), Gaps = 5/284 (1%) Query 5 SVREWRDGGRWLPTAVGKV-FVRSGPGDTPTMLLLHGYPSSSFDF-RAVIPHLTGQAWVT 62 ++ EWR G+ L + + +G +LL+HG+PS+S+D+ R +P V Sbjct 8 ALDEWRSQGQVLDFRGHSIRYWVAGDAAAEPLLLIHGFPSASWDWHRLWVPLAARYRLVA 67 Query 63 MDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLD 121 D LGFG S KPR H YSLLEQA L + ++AH V VLAHD G SV EL+AR D Sbjct 68 CDMLGFGYSAKPRGHAYSLLEQADLQQVLLAHIGEQRRVHVLAHDYGDSVAQELIARHQD 127 Query 122 GRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAH 181 G+L L V NG + E +QK+L PLGP+ RL SR + F RIF P Sbjct 128 GQL--QLASCVFLNGGLFPETHHPVRVQKLLLGPLGPLIGRLFSRRKLAQSFARIFGPHT 185 Query 182 PLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDP 241 S E A W+L+ YN+G + H LI Y+ ER + QRW A++ P+ + G DP Sbjct 186 QASEAELDALWQLVAYNNGPAVMHRLIRYMPERRQQRQRWVAAMQATTLPMRVIDGAFDP 245 Query 242 VATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSL 285 ++ +++ REL A V L G+GHYPQ+EAP A E L Sbjct 246 ISGAHMVARYRELIADADTVLLDGIGHYPQLEAPVAVLEHYLQF 289 >gi|37589663|gb|AAH59471.1| Mesoderm specific transcript [Danio rerio] Length=343 Score = 164 bits (414), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 102/297 (35%), Positives = 160/297 (54%), Gaps = 14/297 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 SP++ WR G + +F + G + ++LLHG+P+SS+D+ + LT + Sbjct 45 SPALNSWRTSGHFFTFRGNDIFYKESVGVVGSSDVLVLLHGFPTSSYDWYKIWDSLTQRF 104 Query 60 --WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGA--VVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPHRYS+ EQA +VE +VAH + +L+HD G +V EL Sbjct 105 NRVIALDFLGFGFSDKPRPHRYSIFEQASVVEALVAHLGLSEQRINILSHDYGDTVALEL 164 Query 116 LARDLDGRLPFDLRRAV-LSNGSVILERASLRPIQKVLRSP--LGPVAARLVSRGGFTRG 172 L R R + ++ LSNG + E R +QKVL+ + PV RL++ +RG Sbjct 165 LYRSDHNRSGHIIVNSLCLSNGGIFPETHHPRFLQKVLKDSGFISPVLTRLMNFQLISRG 224 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 +F P + E W + +NDGN + L+ Y+++R++H +RW GA+ PL Sbjct 225 IKEVFGPYTQPTEAEVWDMWTGIRFNDGNLVMDSLLQYINQRLKHRERWVGALTSTLTPL 284 Query 233 GFVWGLDDPVA-TTNVLNGLREL--RPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L ++L R + +V++ + HYPQ+E P + A LS + Sbjct 285 HMIYGPLDPVNPHPQFLQLYQKLVQRSTVSVLD-EHVSHYPQLEDPTGFFNAYLSFI 340 >gi|85708903|ref|ZP_01039969.1| hydrolase, alpha/beta fold family protein [Erythrobacter sp. NAP1] gi|85690437|gb|EAQ30440.1| hydrolase, alpha/beta fold family protein [Erythrobacter sp. NAP1] Length=288 Score = 163 bits (413), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 98/285 (35%), Positives = 145/285 (51%), Gaps = 3/285 (1%) Query 5 SVREWRDGGRWLPTAVGKV-FVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQA-WVT 62 + R+W + + K+ + G + +LL+HG+P+ S+D+ V L + + Sbjct 4 TTRDWHNRAKQFHFDGHKIAYWTGGDPEARPLLLVHGFPTCSWDWVPVWDTLAEKHHLIA 63 Query 63 MDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDG 122 D LGFGLSDKPR YS+ Q L E ++ G L HD G SV ELLA+ DG Sbjct 64 CDMLGFGLSDKPRS-GYSIHRQTDLQEALLGELGVGEFDALVHDYGVSVGQELLAQQQDG 122 Query 123 RLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHP 182 L + V NG + ++ RP+QK+ SP G + ++SR GF + F +F P Sbjct 123 SGAKGLGKMVFLNGGIFPDQHRPRPMQKLGVSPFGFLLGLMMSRKGFGKSFSEVFGPDTQ 182 Query 183 LSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPV 242 S +E WE + Y DGNRI H L+ Y+ +R+ + +RW A+ +G + G DPV Sbjct 183 PSEKELDEFWEFISYKDGNRITHKLLHYIADRVENKERWEAALVGAQDKIGLINGALDPV 242 Query 243 ATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLV 287 + + + E+ P A + +GHYPQVEAP A AL L Sbjct 243 SGKHAYDKWCEVLPDARHHLIENVGHYPQVEAPDEVAAKALEWLT 287 >gi|18859023|ref|NP_571118.1| mesoderm specific transcript [Danio rerio] gi|6319171|gb|AAF07194.1|AF194334_1 Peg1/Mest [Danio rerio] Length=344 Score = 162 bits (410), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 102/297 (35%), Positives = 160/297 (54%), Gaps = 14/297 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTGQA 59 SP++ R G + +F + G + ++LLHG+P+SS+D+ + LT + Sbjct 46 SPALNSCRTSGHFFTFRGNDIFYKESVGVVGSSDVLVLLHGFPTSSYDWYKIWDSLTQRF 105 Query 60 --WVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGA--VVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPHRYS+ EQA +VE +VAH + +L+HD G +V EL Sbjct 106 NRVIALDFLGFGFSDKPRPHRYSIFEQASVVEALVAHLGLSEQRINILSHDYGDTVALEL 165 Query 116 LARDLDGRLPFDLRRAV-LSNGSVILERASLRPIQKVLRSP--LGPVAARLVSRGGFTRG 172 L R R + ++ LSNG + E R +QKVL+ + PV RL++ F+RG Sbjct 166 LYRSDHNRSGHIIVNSLCLSNGGIFPETHHPRFLQKVLKDSGFISPVLTRLMNFQLFSRG 225 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 +F P + E W + +NDGN + L+ Y+++R++H +RW GA+ PL Sbjct 226 IKEVFGPYTQPTEAEVWDMWTGIRFNDGNLVMDSLLQYINQRLKHRERWVGALTSTLTPL 285 Query 233 GFVWGLDDPVA-TTNVLNGLREL--RPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L ++L R + +V++ + HYPQ+E P + A LS + Sbjct 286 HMIYGPLDPVNPHPQFLQLYQKLVQRSTVSVLD-EHVSHYPQLEDPTGFFNAYLSFI 341 >gi|146217635|gb|ABQ10905.1| mesoderm-specific transcript protein [Bufo gargarizans] Length=326 Score = 162 bits (409), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 99/296 (34%), Positives = 156/296 (53%), Gaps = 12/296 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRS---GPGDTPTMLLLHGYPSSSFDFRAVIPHLTG-- 57 SP++ WR G + +F R G + +++LHG+P+SS+D+ + LT Sbjct 28 SPALFTWRSFGAFFTFQEQHIFYRESWGAVGSSDVVIILHGFPTSSYDWYKIWEGLTQRF 87 Query 58 QAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHT--VTGAVVVLAHDMGTSVTTEL 115 Q + +DF+GFG SDKPR HRYS+ EQA +VE +++H V +L+HD G +V EL Sbjct 88 QRVIALDFIGFGFSDKPRFHRYSIFEQASIVEALISHLGLTDQKVNLLSHDYGDTVAQEL 147 Query 116 LARDLDGRL-PFDLRRAVLSNGSVILERASLRPIQKVLRS--PLGPVAARLVSRGGFTRG 172 L R R ++ LSNG + E R IQK+L+ P+ RL++ F++G Sbjct 148 LYRYEHQRQGHINIGSLCLSNGGIFPETHHPRLIQKLLKDGGIFSPILTRLMNFYFFSKG 207 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 G +F P S E W L NDGN + ++ Y+++R ++ +RW GA+ + PL Sbjct 208 IGEVFGPYTQPSDTEYWDMWTALRINDGNLVVDSILQYINQRRKYRERWVGALTNSSVPL 267 Query 233 GFVWGLDDPVA-TTNVLNGLRELRPSAAVVELPG-LGHYPQVEAPKAYAEAALSLL 286 ++G DPV L+ ++L P + L + HYPQ+E P + A L+ + Sbjct 268 HLIYGPLDPVNPHPEFLDQYKKLIPKSTFTVLDDHISHYPQLEDPTGFLNAYLNFI 323 >gi|296388054|ref|ZP_06877529.1| putative epoxide hydrolase [Pseudomonas aeruginosa PAb1] gi|334837157|gb|EGM15931.1| putative epoxide hydrolase [Pseudomonas aeruginosa 152504] Length=298 Score = 162 bits (409), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 105/260 (41%), Positives = 144/260 (56%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+PS+++D+ + L + V D LGFG S KPR HRYSLLEQA L Sbjct 33 GQGRPLLLIHGFPSAAWDWHYLWEPLAQRYRVLVCDLLGFGDSAKPRAHRYSLLEQADLQ 92 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++ H V + VLAHD G SV ELLAR +GRL L V NG + E + RP Sbjct 93 QALLGHLGVDEPLHVLAHDYGDSVAQELLARHHEGRL--RLASCVFLNGGLFPE--THRP 148 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + RL R R F ++F P E A W L+ N G R+ H Sbjct 149 VLSQKLLLSPLGGLFGRLFDRRALARNFAKVFGPRSQPGETELDAFWSLIESNQGQRVMH 208 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ +R +RW A++ PL + G DP++ +++ R+L +A V L G Sbjct 209 RLIRYIVDRREQRERWVAALQHGGVPLRVIDGAVDPLSGAHMVERYRQLVANADCVLLDG 268 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A E L+ Sbjct 269 IGHYPQIEAPAAVLEHYLAF 288 >gi|83859043|ref|ZP_00952564.1| hydrolase, alpha/beta fold family protein [Oceanicaulis alexandrii HTCC2633] gi|83852490|gb|EAP90343.1| hydrolase, alpha/beta fold family protein [Oceanicaulis alexandrii HTCC2633] Length=306 Score = 162 bits (409), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 99/281 (36%), Positives = 147/281 (53%), Gaps = 8/281 (2%) Query 5 SVREWRDGGRWLPTAVGKVFVRSG----PGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW 60 S+ WR G + ++F R+G D P ++L+HG+P++S+D+ + L Sbjct 6 SLEAWRAAGAYFNYRGYEIFYRTGGDWDDADKPVLVLIHGFPTASWDWVRLWDQLCADYR 65 Query 61 VT-MDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARD 119 V +D +GFG SDKP H YS+++QA L + A + HD G +V ELLAR Sbjct 66 VAALDMIGFGYSDKPADHAYSIMDQADLHDAFFAQLGIKRCHLFVHDYGDTVGQELLARY 125 Query 120 LDGR--LPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIF 177 L+ +L NG + E+ Q++L SPLGPV +RL++R F +G G +F Sbjct 126 LEQGEGAAVELLSICFLNGGLFPEQHRATLTQRLLHSPLGPVLSRLMNRARFAKGLGEVF 185 Query 178 SPAHPLSAQEAQAQWELLCYNDGN-RIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVW 236 P S E A W L G RI H L+ Y+D+R +H RW GA+ + P+ + Sbjct 186 GPDTQPSEAEMDAFWALAMEKGGMPRIGHKLLGYIDDRRQHRDRWVGALVNSTVPMRVID 245 Query 237 GLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKA 277 G DPV+ +++ REL P+ + LP +GHYP E PKA Sbjct 246 GALDPVSGAHMVARYRELVPNPDTLLLPHVGHYPHWEDPKA 286 >gi|152984185|ref|YP_001347081.1| putative epoxide hydrolase [Pseudomonas aeruginosa PA7] gi|150959343|gb|ABR81368.1| probable epoxide hydrolase [Pseudomonas aeruginosa PA7] Length=298 Score = 160 bits (406), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 105/260 (41%), Positives = 143/260 (55%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+PS+++D+ + L + V D LGFG S KPR HRYSLLEQA L Sbjct 33 GQGKPLLLIHGFPSAAWDWHYLWEPLARRYRVLACDMLGFGDSAKPRGHRYSLLEQADLQ 92 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++ + + VLAHD G SV ELLAR +GRL L V NG + E + RP Sbjct 93 QALLGRLGIDQPLHVLAHDYGDSVAQELLARHHEGRL--RLASCVFLNGGLFPE--THRP 148 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + ARL R R F R+F P E A W L+ N G R+ H Sbjct 149 VLSQKLLLSPLGGLFARLFDRRALARNFARVFGPRSQPGEAELDAFWSLIESNQGQRVMH 208 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ +R +RW A++ PL + G DP++ +++ R+L A V L G Sbjct 209 RLIRYIVDRREQRERWVAALQHGGVPLRVIDGAVDPISGAHMVERYRQLVRDADCVLLDG 268 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A E L+ Sbjct 269 IGHYPQIEAPGAVLEHYLAF 288 >gi|70728342|ref|YP_258091.1| alpha/beta fold family hydrolase [Pseudomonas fluorescens Pf-5] gi|68342641|gb|AAY90247.1| alpha/beta hydrolase family protein [Pseudomonas fluorescens Pf-5] Length=300 Score = 159 bits (402), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 103/260 (40%), Positives = 143/260 (55%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAV-IPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+P++S+D+ + P + D LGFG S KP H YSLLEQA L Sbjct 31 GQGEPLLLIHGFPTASWDWHYLWQPLARHHQMIACDMLGFGDSAKPLEHDYSLLEQADLQ 90 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++AH + V +LAHD G SV ELLAR + R+ D+ V NG + E + RP Sbjct 91 QALLAHLGIAEPVHLLAHDYGDSVAQELLARHYEERI--DIASCVFLNGGLFPE--THRP 146 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + R SR G + F +IF P + S W L+ NDG RI H Sbjct 147 VLTQKLLLSPLGWMLGRTFSRQGLAKSFRQIFGPQNRPSESVLDDFWSLVQSNDGPRILH 206 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ ER +RW A++ PL + G DP++ +++ R+L P A V LP Sbjct 207 KLIGYIPERRARRERWVSAMQRGEVPLRVIDGALDPISGAHMVERYRQLIPRADTVLLPN 266 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A + L Sbjct 267 IGHYPQIEAPLAVLKHYLEF 286 >gi|260816096|ref|XP_002602808.1| hypothetical protein BRAFLDRAFT_281939 [Branchiostoma floridae] gi|229288120|gb|EEN58820.1| hypothetical protein BRAFLDRAFT_281939 [Branchiostoma floridae] Length=344 Score = 159 bits (401), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 103/301 (35%), Positives = 155/301 (52%), Gaps = 15/301 (4%) Query 1 VTSPSVREWRDGGRWLPTAVGKVFV--RSGPGDT-PTMLLLHGYPSSSFDFRAVIPHLTG 57 + SP +REW+ G++ KVF +G G+ +L +HG+PSSS D+ V L G Sbjct 29 ILSPQLREWKQSGKFFSHGEFKVFYHDETGKGEAGEVVLCIHGFPSSSHDWVKVWDGLQG 88 Query 58 QAW--VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTEL 115 + + D LGFG SDKP H YS+ EQA ++E ++ V +L+HD G +V EL Sbjct 89 RFGRVIASDLLGFGFSDKPLDHNYSIFEQASIIEQLLETLEVKEVYILSHDYGDTVALEL 148 Query 116 LARDLDGRLPFD-------LRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGG 168 L R LD + + +R L NG + E + + +Q +L + LGP +RL + Sbjct 149 LRRFLDRQKSSEKSAAHLRIRSVCLMNGGFLPETITFQWVQYLLTTSLGPYLSRLSNFLP 208 Query 169 FT--RGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVR 226 FT +G +++ P S E LL +NDG+ + Y +ER+ H +RW AV+ Sbjct 209 FTFKQGISKVYGPDTKPSPAEYDDHQTLLRWNDGHLAMGSISQYQNERVAHRERWVEAVQ 268 Query 227 DWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG-LGHYPQVEAPKAYAEAALSL 285 P+ ++G DPV T +L+ REL P A L +GHYP VE P++ A + Sbjct 269 QSTIPVHLIYGPADPVNTPVLLDRYRELFPRATDTVLNSKIGHYPHVEDPQSVLTAFFNF 328 Query 286 L 286 L Sbjct 329 L 329 >gi|15598625|ref|NP_252119.1| epoxide hydrolase [Pseudomonas aeruginosa PAO1] gi|218890371|ref|YP_002439235.1| putative epoxide hydrolase [Pseudomonas aeruginosa LESB58] gi|254236383|ref|ZP_04929706.1| hypothetical protein PACG_02363 [Pseudomonas aeruginosa C3719] 6 more sequence titles Length=298 Score = 159 bits (401), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 103/260 (40%), Positives = 142/260 (55%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+PS+++D+ + L + V D LGFG S KPR HRYSLLEQA L Sbjct 33 GQGRPLLLIHGFPSAAWDWHYLWEPLAQRYRVLVCDLLGFGDSAKPRAHRYSLLEQADLQ 92 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++ + + VLAHD G SV ELLAR +GRL L V NG + E + RP Sbjct 93 QALLGRLGIDEPLHVLAHDYGDSVAQELLARHHEGRL--RLASCVFLNGGLFPE--THRP 148 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + RL R R F ++F P E A W L+ N G R+ H Sbjct 149 VLSQKLLLSPLGGLFGRLFDRRALARNFAKVFGPRSQPGETELDAFWSLIESNQGQRVMH 208 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ +R +RW A++ PL + G DP++ +++ R+L A V L G Sbjct 209 RLIRYIVDRREQRERWVAALQHGGVPLRVIDGAVDPISGAHMVERYRQLVADADCVLLDG 268 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A E L+ Sbjct 269 IGHYPQIEAPAAVLEHYLAF 288 >gi|116051449|ref|YP_789718.1| alpha/beta family hydrolase [Pseudomonas aeruginosa UCBPP-PA14] gi|115586670|gb|ABJ12685.1| putative hydrolase, alpha/beta fold family [Pseudomonas aeruginosa UCBPP-PA14] Length=298 Score = 158 bits (400), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 104/260 (40%), Positives = 142/260 (55%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+PS+++D+ + L + V D LGFG S KPR HRYSLLEQA L Sbjct 33 GQGRPLLLIHGFPSAAWDWHYLWEPLAQRYRVLVCDLLGFGDSAKPRAHRYSLLEQADLQ 92 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++ V + VLAHD G SV ELLAR +GRL L V NG + E + RP Sbjct 93 QGLLGRLGVDEPLHVLAHDYGDSVAQELLARHHEGRL--RLASCVFLNGGLFPE--THRP 148 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + RL R R F ++F P E A W L+ N G R+ H Sbjct 149 VLSQKLLLSPLGGLFGRLFDRRALARNFAKVFGPRSQPGETELDAFWSLIESNQGQRVMH 208 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ +R +RW A++ PL + G DP++ +++ R+L A V L G Sbjct 209 RLIRYIVDRREQRERWVAALQHGGVPLRVIDGAVDPISGAHMVERYRQLVADADCVLLDG 268 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A E L+ Sbjct 269 IGHYPQIEAPAAVLEHYLAF 288 >gi|149411652|ref|XP_001511333.1| PREDICTED: mesoderm-specific transcript homolog protein-like [Ornithorhynchus anatinus] Length=326 Score = 158 bits (400), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 106/298 (36%), Positives = 158/298 (54%), Gaps = 16/298 (5%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLTG-- 57 SP+++ W+ G + +F + G + ++LLHG+P+SS+D+ + LT Sbjct 28 SPALQAWKSSGTFFIYEGLSIFYQDSQGALGSSEIVVLLHGFPTSSYDWCKIWEGLTQRF 87 Query 58 QAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHT-VTGAVV-VLAHDMGTSVTTEL 115 Q + +DFLGFG SDKPR HRYS+ EQA +VE ++ H V G + +LAHD G +V EL Sbjct 88 QRVIALDFLGFGFSDKPRSHRYSIFEQASIVEGLLEHLGVRGQRIHLLAHDYGDTVAQEL 147 Query 116 LAR---DLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRS--PLGPVAARLVSRGGFT 170 L R + GR+ + LSNG + E R +QKVL+ PL P+ RL++ F+ Sbjct 148 LYRYEHNQTGRVL--ISSLCLSNGGIFPETTHPRFLQKVLQDGGPLSPILNRLMNFFLFS 205 Query 171 RGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPK 230 RG +F P S E W + DGN + L+ Y+++R + RW GA+ Sbjct 206 RGISEVFGPYTQPSEAELWDMWTGIRAEDGNLVAGSLLQYINQRKQQRDRWVGALTSTAI 265 Query 231 PLGFVWGLDDPVA-TTNVLNGLRELRPSAAVVELPG-LGHYPQVEAPKAYAEAALSLL 286 PL ++G DPV +N R+L P + V L + HYPQ+E P + A LS + Sbjct 266 PLHIIYGPLDPVNPHPEFINLYRKLLPQSTVSILDDHISHYPQLEDPMGFLRAYLSFI 323 >gi|8926696|emb|CAB96533.1| mesoderm specific transcript [Takifugu rubripes] Length=326 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 97/296 (33%), Positives = 153/296 (52%), Gaps = 12/296 (4%) Query 3 SPSVREWRDGGRWLPTAVGKVFVRSGPG---DTPTMLLLHGYPSSSFDFRAVIPHLT--G 57 SP++++W+ G K+F R G + ++LLHG+P+SS+D+ + L Sbjct 28 SPALQKWQSAGDVFHFRGNKIFYRDSYGALGSSDVLILLHGFPTSSYDWHKIWEPLALRF 87 Query 58 QAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHT--VTGAVVVLAHDMGTSVTTEL 115 + +DFLGFG SDKPRPH+YS+ EQA +VE +VAH V +++HD G +V EL Sbjct 88 HRVIALDFLGFGFSDKPRPHKYSIFEQASVVEALVAHLGLSNQRVNLISHDYGDTVALEL 147 Query 116 LARDLDGRL-PFDLRRAVLSNGSVILERASLRPIQKVLR--SPLGPVAARLVSRGGFTRG 172 L R R L LSNG + E R +Q +L+ S L P+ RL + F +G Sbjct 148 LYRSDQNRTGHLTLNSLCLSNGGLFPETHHPRLLQTLLKDSSFLAPLLTRLTNFMIFQKG 207 Query 173 FGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPL 232 G +F P + + W + YNDGN + ++ Y+++R++H +RW GA+ PL Sbjct 208 IGEVFGPYTQPTNADFWDMWSSIRYNDGNLVMDSILQYINQRLKHRERWVGALTSTFVPL 267 Query 233 GFVWGLDDPVATTNVLNGLRE--LRPSAAVVELPGLGHYPQVEAPKAYAEAALSLL 286 ++G DPV L + ++ S + + HYPQ+E P + A + + Sbjct 268 HMIYGPLDPVNPHPQFIRLYQQLVQRSTLTILDEHISHYPQLEDPTGFLNAYFNFI 323 >gi|313108785|ref|ZP_07794772.1| putative hydrolase, alpha/beta fold family [Pseudomonas aeruginosa 39016] gi|310881274|gb|EFQ39868.1| putative hydrolase, alpha/beta fold family [Pseudomonas aeruginosa 39016] Length=298 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 103/260 (40%), Positives = 142/260 (55%), Gaps = 8/260 (3%) Query 30 GDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWV-TMDFLGFGLSDKPRPHRYSLLEQAHLV 88 G +LL+HG+PS+++D+ + L + V D LGFG S KPR HRYSLLEQA L Sbjct 33 GQGRPLLLIHGFPSAAWDWHYLWEPLAQRYRVLVCDLLGFGDSAKPRAHRYSLLEQADLQ 92 Query 89 ETVVAHT-VTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRP 147 + ++ + + VLAHD G SV ELLAR +GRL L V NG + E + RP Sbjct 93 QALLGCLGIDEPLHVLAHDYGDSVAQELLARHHEGRL--RLASCVFLNGGLFPE--THRP 148 Query 148 I--QKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPH 205 + QK+L SPLG + RL R R F ++F P E A W L+ N G R+ H Sbjct 149 VLSQKLLLSPLGGLFGRLFDRRALARNFAKVFGPRSQPGETELDAFWSLIESNQGQRVMH 208 Query 206 LLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPG 265 LI Y+ +R +RW A++ PL + G DP++ +++ R+L A V L G Sbjct 209 RLIRYIVDRREQRERWVAALQHGGVPLRVIDGAVDPISGAHMVERYRKLVADADCVLLDG 268 Query 266 LGHYPQVEAPKAYAEAALSL 285 +GHYPQ+EAP A E L+ Sbjct 269 IGHYPQIEAPAAVLEHYLAF 288 Lambda K H 0.322 0.138 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 467727525600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40