BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1856c

Length=225
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608993|ref|NP_216372.1|  short chain dehydrogenase [Mycobact...   449    1e-124
gi|31793046|ref|NP_855539.1|  short chain dehydrogenase [Mycobact...   447    6e-124
gi|297634416|ref|ZP_06952196.1|  short chain dehydrogenase [Mycob...   444    4e-123
gi|240172039|ref|ZP_04750698.1|  short chain dehydrogenase [Mycob...   397    6e-109
gi|183982736|ref|YP_001851027.1|  oxidoreductase [Mycobacterium m...   394    8e-108
gi|118618414|ref|YP_906746.1|  short chain dehydrogenase [Mycobac...   392    3e-107
gi|296164847|ref|ZP_06847405.1|  short-chain dehydrogenase/reduct...   384    5e-105
gi|254821983|ref|ZP_05226984.1|  short chain dehydrogenase [Mycob...   380    8e-104
gi|41407662|ref|NP_960498.1|  short chain dehydrogenase [Mycobact...   379    2e-103
gi|254775340|ref|ZP_05216856.1|  short chain dehydrogenase [Mycob...   378    3e-103
gi|342861247|ref|ZP_08717895.1|  short chain dehydrogenase [Mycob...   378    3e-103
gi|336457612|gb|EGO36617.1|  dehydrogenase of unknown specificity...   374    5e-102
gi|118463407|ref|YP_882050.1|  short chain dehydrogenase [Mycobac...   373    9e-102
gi|15828110|ref|NP_302373.1|  short chain dehydrogenase [Mycobact...   372    2e-101
gi|333990584|ref|YP_004523198.1|  oxidoreductase [Mycobacterium s...   329    2e-88 
gi|108799765|ref|YP_639962.1|  short chain dehydrogenase [Mycobac...   310    9e-83 
gi|118473731|ref|YP_887922.1|  short chain dehydrogenase [Mycobac...   308    5e-82 
gi|120404055|ref|YP_953884.1|  short chain dehydrogenase [Mycobac...   268    4e-70 
gi|145223932|ref|YP_001134610.1|  short chain dehydrogenase [Myco...   262    2e-68 
gi|169629518|ref|YP_001703167.1|  short chain dehydrogenase [Myco...   223    2e-56 
gi|294816238|ref|ZP_06774881.1|  oxidoreductase [Streptomyces cla...   112    3e-23 
gi|254391842|ref|ZP_05007036.1|  3-oxoacyl-[acyl-carrier-protein]...   112    3e-23 
gi|312197069|ref|YP_004017130.1|  short-chain dehydrogenase/reduc...   107    1e-21 
gi|256396641|ref|YP_003118205.1|  short-chain dehydrogenase/reduc...   107    2e-21 
gi|134100225|ref|YP_001105886.1|  3-oxoacyl-[acyl-carrier-protein...   103    2e-20 
gi|284031480|ref|YP_003381411.1|  short-chain dehydrogenase/reduc...   102    4e-20 
gi|291302433|ref|YP_003513711.1|  short-chain dehydrogenase/reduc...  99.0    5e-19 
gi|226308780|ref|YP_002768740.1|  oxidoreductase [Rhodococcus ery...  98.6    7e-19 
gi|302545655|ref|ZP_07297997.1|  3-oxoacyl-(acyl-carrier-protein)...  97.4    1e-18 
gi|229489268|ref|ZP_04383134.1|  3-oxoacyl-[acyl-carrier-protein]...  95.5    5e-18 
gi|332669331|ref|YP_004452339.1|  short-chain dehydrogenase/reduc...  86.7    2e-15 
gi|271962845|ref|YP_003337041.1|  short chain dehydrogenase prote...  85.5    5e-15 
gi|222108964|ref|YP_002551230.1|  short chain dehydrogenase prote...  82.8    4e-14 
gi|326334087|ref|ZP_08200315.1|  3-oxoacyl-acyl carrier protein r...  82.4    5e-14 
gi|159036112|ref|YP_001535365.1|  short-chain dehydrogenase/reduc...  77.4    1e-12 
gi|337765846|emb|CCB74555.1|  conserved protein of unknown functi...  76.3    4e-12 
gi|302540248|ref|ZP_07292590.1|  short-chain dehydrogenase/reduct...  75.5    6e-12 
gi|145592940|ref|YP_001157237.1|  short-chain dehydrogenase/reduc...  75.1    7e-12 
gi|311898812|dbj|BAJ31220.1|  putative oxidoreductase [Kitasatosp...  74.7    8e-12 
gi|297155572|gb|ADI05284.1|  Putative 3-oxacyl-ACP reductase [Str...  74.3    1e-11 
gi|316305717|gb|ADU56362.1|  3-oxoacyl-ACP reductase [Streptomyce...  74.3    1e-11 
gi|302530269|ref|ZP_07282611.1|  3-oxoacyl-[acyl-carrier-protein]...  73.9    2e-11 
gi|238025266|ref|YP_002909498.1|  putative 3-oxacyl-ACP reductase...  73.2    2e-11 
gi|300783255|ref|YP_003763546.1|  3-oxoacyl-[acyl-carrier-protein...  73.2    3e-11 
gi|300790037|ref|YP_003770328.1|  3-oxoacyl-[acyl-carrier-protein...  70.9    1e-10 
gi|333372061|ref|ZP_08463997.1|  3-oxoacyl-[acyl-carrier-protein]...  70.5    2e-10 
gi|345011260|ref|YP_004813614.1|  short-chain dehydrogenase/reduc...  69.7    3e-10 
gi|298249729|ref|ZP_06973533.1|  short-chain dehydrogenase/reduct...  69.3    4e-10 
gi|330470238|ref|YP_004407981.1|  short-chain dehydrogenase/reduc...  68.6    6e-10 
gi|167583993|ref|ZP_02376381.1|  putative 3-oxacyl-ACP reductase ...  67.8    1e-09 


>gi|15608993|ref|NP_216372.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv]
 gi|15841324|ref|NP_336361.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551]
 gi|148661662|ref|YP_001283185.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Ra]
 45 more sequence titles
 Length=225

 Score =  449 bits (1155),  Expect = 1e-124, Method: Compositional matrix adjust.
 Identities = 225/225 (100%), Positives = 225/225 (100%), Gaps = 0/225 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS
Sbjct  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD
Sbjct  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY
Sbjct  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG
Sbjct  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225


>gi|31793046|ref|NP_855539.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97]
 gi|121637759|ref|YP_977982.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224990243|ref|YP_002644930.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|31618637|emb|CAD94590.1| POSSIBLE OXIDOREDUCTASE [Mycobacterium bovis AF2122/97]
 gi|121493406|emb|CAL71879.1| Possible oxidoreductase [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224773356|dbj|BAH26162.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|341601786|emb|CCC64460.1| possible oxidoreductase [Mycobacterium bovis BCG str. Moreau 
RDJ]
Length=225

 Score =  447 bits (1149),  Expect = 6e-124, Method: Compositional matrix adjust.
 Identities = 224/225 (99%), Positives = 224/225 (99%), Gaps = 0/225 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS
Sbjct  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD
Sbjct  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY
Sbjct  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            EGLS TPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG
Sbjct  181  EGLSHTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225


>gi|297634416|ref|ZP_06952196.1| short chain dehydrogenase [Mycobacterium tuberculosis KZN 4207]
 gi|308231958|ref|ZP_07414412.2| oxidoreductase [Mycobacterium tuberculosis SUMu001]
 gi|308369538|ref|ZP_07418192.2| oxidoreductase [Mycobacterium tuberculosis SUMu002]
 25 more sequence titles
 Length=223

 Score =  444 bits (1142),  Expect = 4e-123, Method: Compositional matrix adjust.
 Identities = 222/223 (99%), Positives = 223/223 (100%), Gaps = 0/223 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            +EVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT
Sbjct  1    MEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL
Sbjct  61   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG
Sbjct  121  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG
Sbjct  181  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  223


>gi|240172039|ref|ZP_04750698.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478]
Length=225

 Score =  397 bits (1020),  Expect = 6e-109, Method: Compositional matrix adjust.
 Identities = 193/224 (87%), Positives = 208/224 (93%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRT+AEGFR+DGHKVTLVGARR +LEV AKEL+VDA+ CDTT+P S
Sbjct  1    MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDELEVVAKELEVDAIACDTTNPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L+E R LFP HLDTIVNVPAPSWDAGDPR YS+SDTA AWRNALDATVLS VLTVQ VGD
Sbjct  61   LSEVRSLFPHHLDTIVNVPAPSWDAGDPRTYSLSDTAAAWRNALDATVLSAVLTVQCVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+ VVAENPPAG A++A+KAALSNW+AGQA V+GTRGIT+N VACGRSVQ GY
Sbjct  121  HLRSGGSIIGVVAENPPAGSADAAVKAALSNWVAGQAEVYGTRGITVNAVACGRSVQPGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF
Sbjct  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224


>gi|183982736|ref|YP_001851027.1| oxidoreductase [Mycobacterium marinum M]
 gi|183176062|gb|ACC41172.1| oxidoreductase [Mycobacterium marinum M]
Length=225

 Score =  394 bits (1011),  Expect = 8e-108, Method: Compositional matrix adjust.
 Identities = 190/224 (85%), Positives = 204/224 (92%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRT+AEGFR+DGHKVTLVGARR DLEV AKELD DA+ CD T+P S
Sbjct  1    MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADAIACDITNPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L E RGLFP HLDTIVNVPAP+WDAGDPR YS++DTA AWRNALD TVLS VLTVQ VGD
Sbjct  61   LAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAWRNALDTTVLSAVLTVQCVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVVAENPPAG  ++AIK ALSNW+AGQA ++GTRGIT+N VACGRSVQ GY
Sbjct  121  HLRSGGSIISVVAENPPAGSVDAAIKGALSNWVAGQAEIYGTRGITVNAVACGRSVQAGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF
Sbjct  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224


>gi|118618414|ref|YP_906746.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99]
 gi|118570524|gb|ABL05275.1| oxidoreductase [Mycobacterium ulcerans Agy99]
Length=225

 Score =  392 bits (1006),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 189/224 (85%), Positives = 203/224 (91%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRT+AEGFR+DGHKVTLVGARR DLEV AKELD DA+ CD T+P S
Sbjct  1    MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADAIACDITNPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L E RGLFP HLDTIVNVPAP+WDAGDPR YS++DTA AWRNALD T LS VLTVQ VGD
Sbjct  61   LAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAWRNALDTTALSAVLTVQCVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVVAENPPAG  ++AIK ALSNW+AGQA ++GTRGIT+N VACGRSVQ GY
Sbjct  121  HLRSGGSIISVVAENPPAGSVDAAIKGALSNWVAGQAEIYGTRGITVNAVACGRSVQAGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF
Sbjct  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224


>gi|296164847|ref|ZP_06847405.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295899813|gb|EFG79261.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=225

 Score =  384 bits (986),  Expect = 5e-105, Method: Compositional matrix adjust.
 Identities = 183/225 (82%), Positives = 207/225 (92%), Gaps = 0/225 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDT+LGR +AEGFR+DGHKVTLVGARR +LE+AAKELDVDA+VCDTTDP S
Sbjct  1    MAVEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARRSELEIAAKELDVDAIVCDTTDPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            LTEARGLFP HLDTIVNVPAPSW+AGDPR YS++DTA AWRN+LDATVLS VLTVQ+VGD
Sbjct  61   LTEARGLFPHHLDTIVNVPAPSWEAGDPRTYSIADTATAWRNSLDATVLSAVLTVQTVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVV +NPPAG  ++AIKA LSNW++GQA++FGTRGIT+N VA GRS Q GY
Sbjct  121  HLRSGGSIISVVPDNPPAGSVDAAIKATLSNWVSGQASIFGTRGITVNAVASGRSAQPGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            +GLSRTP  VAAE+ARLALFLT+P+ARHITGQTLHVSHGALA FG
Sbjct  181  DGLSRTPPSVAAEVARLALFLTSPSARHITGQTLHVSHGALAQFG  225


>gi|254821983|ref|ZP_05226984.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 
13950]
Length=225

 Score =  380 bits (976),  Expect = 8e-104, Method: Compositional matrix adjust.
 Identities = 182/224 (82%), Positives = 205/224 (92%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDT+LGR +AEGFR+DGHKVTLVGAR+ DLE+AAKEL+V+A+VCDTTDP S
Sbjct  1    MAVEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEVEAIVCDTTDPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L EAR LFP HLDTIVNVPAP+W+AGDPR YS++DTANAWR ALDATVLS VLT+Q+VGD
Sbjct  61   LEEARPLFPHHLDTIVNVPAPTWEAGDPRTYSIADTANAWRKALDATVLSAVLTLQTVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVV ENPPAG A++AIKA L+NW AGQA+VFGTRGIT+N VA GRS Q GY
Sbjct  121  HLRSGGSIISVVPENPPAGSADAAIKATLANWTAGQASVFGTRGITVNAVASGRSAQAGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            +GL+RTPAPVAAE+ARLALFLTT AARHITGQTLHVSHGALA F
Sbjct  181  DGLTRTPAPVAAEVARLALFLTTSAARHITGQTLHVSHGALAQF  224


>gi|41407662|ref|NP_960498.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396015|gb|AAS03881.1| hypothetical protein MAP_1564c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=225

 Score =  379 bits (973),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 180/224 (81%), Positives = 206/224 (92%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDT+LGR +AEGFR+DGHKVTLVGAR+ DLE+AAKEL+ +A+VCDTTDP +
Sbjct  1    MAVEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEAIVCDTTDPAA  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L +AR LFP HLDTIV+VPAPSW+AGDPR YS++DTA+AWRNALDATVLS VLTVQ+VGD
Sbjct  61   LEQARPLFPHHLDTIVHVPAPSWEAGDPRTYSIADTASAWRNALDATVLSAVLTVQTVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVV ENPPAG A++A+KAALSNW  GQA+VFGTRGIT+N VA GR  Q GY
Sbjct  121  HLRSGGSIISVVPENPPAGSAQAAVKAALSNWTTGQASVFGTRGITVNAVASGRGAQPGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            +GLSR+PAPVAAE+ARLALFLT+PAARHITGQTLHVSHGALAHF
Sbjct  181  DGLSRSPAPVAAEVARLALFLTSPAARHITGQTLHVSHGALAHF  224


>gi|254775340|ref|ZP_05216856.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 
25291]
Length=225

 Score =  378 bits (971),  Expect = 3e-103, Method: Compositional matrix adjust.
 Identities = 179/224 (80%), Positives = 206/224 (92%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDT+LGR +AEGFR+DGHKVTLVGAR+ DLE+AAKEL+ +A+VCDTTDP +
Sbjct  1    MAVEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEAIVCDTTDPAA  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L +AR LFP HLDT+V+VPAPSW+AGDPR YS++DTA+AWRNALDATVLS VLTVQ+VGD
Sbjct  61   LEQARPLFPHHLDTVVHVPAPSWEAGDPRTYSIADTASAWRNALDATVLSAVLTVQTVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+SVV ENPPAG A++A+KAALSNW  GQA+VFGTRGIT+N VA GR  Q GY
Sbjct  121  HLRSGGSIISVVPENPPAGSAQAAVKAALSNWTTGQASVFGTRGITVNAVASGRGAQPGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            +GLSR+PAPVAAE+ARLALFLT+PAARHITGQTLHVSHGALAHF
Sbjct  181  DGLSRSPAPVAAEVARLALFLTSPAARHITGQTLHVSHGALAHF  224


>gi|342861247|ref|ZP_08717895.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035]
 gi|342131147|gb|EGT84428.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035]
Length=225

 Score =  378 bits (971),  Expect = 3e-103, Method: Compositional matrix adjust.
 Identities = 182/224 (82%), Positives = 204/224 (92%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAVEVLVTGGDTDLGRT+AE FR+DGHKVTLVGAR+ DLE+AAKEL+V+A+VCDTTDP S
Sbjct  1    MAVEVLVTGGDTDLGRTVAESFRDDGHKVTLVGARKSDLEIAAKELEVEAIVCDTTDPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L EAR LFP HLDTIVNVPAP+W+AGDPR YS++DTA+AWRNALDATVLS VLTVQ+VGD
Sbjct  61   LEEARPLFPHHLDTIVNVPAPAWEAGDPRTYSIADTASAWRNALDATVLSAVLTVQAVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+S+V ENPPAG A++A+KA LSNW AGQA +FGTRGIT+N VA GRS + GY
Sbjct  121  HLRSGGSIISLVPENPPAGSADAAVKATLSNWTAGQAGIFGTRGITVNVVASGRSAEAGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            +GLSRTPAPVAAE ARLALFLTT AARHITGQTLHVSHGALA F
Sbjct  181  DGLSRTPAPVAAEAARLALFLTTSAARHITGQTLHVSHGALARF  224


>gi|336457612|gb|EGO36617.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase 
like protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=223

 Score =  374 bits (960),  Expect = 5e-102, Method: Compositional matrix adjust.
 Identities = 177/222 (80%), Positives = 204/222 (92%), Gaps = 0/222 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            +EVLVTGGDT+LGR +AEGFR+DGHKVTLVGAR+ DLE+AAKEL+ +A+VCDTTDP +L 
Sbjct  1    MEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEAIVCDTTDPAALE  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            +AR LFP HLDTIV+VPAPSW+AGDPR YS++DTA+AWRNALDATVLS VLTVQ+VGDHL
Sbjct  61   QARPLFPHHLDTIVHVPAPSWEAGDPRTYSIADTASAWRNALDATVLSAVLTVQTVGDHL  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSI+SVV ENPPAG A++A+KAALSNW  GQA+VFGTRGIT+N VA GR  Q GY+G
Sbjct  121  RSGGSIISVVPENPPAGSAQAAVKAALSNWTTGQASVFGTRGITVNAVASGRGAQPGYDG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            LSR+PAPVAAE+ARLALFLT+PAARHITGQTLHVSHGALAHF
Sbjct  181  LSRSPAPVAAEVARLALFLTSPAARHITGQTLHVSHGALAHF  222


>gi|118463407|ref|YP_882050.1| short chain dehydrogenase [Mycobacterium avium 104]
 gi|118164694|gb|ABK65591.1| short chain dehydrogenase [Mycobacterium avium 104]
Length=223

 Score =  373 bits (958),  Expect = 9e-102, Method: Compositional matrix adjust.
 Identities = 176/222 (80%), Positives = 204/222 (92%), Gaps = 0/222 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            +EVLVTGGDT+LGR +AEGFR+DGHKVTLVGAR+ DLE+AAKEL+ +A+VCDTTDP +L 
Sbjct  1    MEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEAIVCDTTDPAALE  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            +AR LFP HLDT+V+VPAPSW+AGDPR YS++DTA+AWRNALDATVLS VLTVQ+VGDHL
Sbjct  61   QARPLFPHHLDTVVHVPAPSWEAGDPRTYSIADTASAWRNALDATVLSAVLTVQTVGDHL  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSI+SVV ENPPAG A++A+KAALSNW  GQA+VFGTRGIT+N VA GR  Q GY+G
Sbjct  121  RSGGSIISVVPENPPAGSAQAAVKAALSNWTTGQASVFGTRGITVNAVASGRGAQPGYDG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            LSR+PAPVAAE+ARLALFLT+PAARHITGQTLHVSHGALAHF
Sbjct  181  LSRSPAPVAAEVARLALFLTSPAARHITGQTLHVSHGALAHF  222


>gi|15828110|ref|NP_302373.1| short chain dehydrogenase [Mycobacterium leprae TN]
 gi|221230587|ref|YP_002504003.1| short chain dehydrogenase [Mycobacterium leprae Br4923]
 gi|2578370|emb|CAA15443.1| oxidoreductase [Mycobacterium leprae]
 gi|13093664|emb|CAC31014.1| short-chain dehydrogenase/reductase family [Mycobacterium leprae]
 gi|219933694|emb|CAR72156.1| short-chain dehydrogenase/reductase family [Mycobacterium leprae 
Br4923]
Length=224

 Score =  372 bits (955),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 180/224 (81%), Positives = 198/224 (89%), Gaps = 0/224 (0%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MAV+VLVTGG+TDLGRT+AEGFRNDGHKVTLVG RR DLEV AKELDVD +VC+TTDP S
Sbjct  1    MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKELDVDTIVCNTTDPAS  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L EARGLFPRHL+TIVNVP   +D GDPR +S+SDTANAW N LDATVLS VLTVQSVGD
Sbjct  61   LDEARGLFPRHLNTIVNVPTLGFDTGDPRTFSLSDTANAWHNELDATVLSAVLTVQSVGD  120

Query  121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
            HLRSGGSI+ V+AENPPAG  ++AIKAALS+W+AGQA VFGTRGIT+N +ACGRSVQ GY
Sbjct  121  HLRSGGSIIGVLAENPPAGSVDAAIKAALSSWVAGQAGVFGTRGITVNAIACGRSVQAGY  180

Query  181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            EGLSR P  VA EI RLALFLTTPA+RHITGQTLHVSHGAL HF
Sbjct  181  EGLSRMPPHVATEITRLALFLTTPASRHITGQTLHVSHGALTHF  224


>gi|333990584|ref|YP_004523198.1| oxidoreductase [Mycobacterium sp. JDM601]
 gi|333486552|gb|AEF35944.1| oxidoreductase [Mycobacterium sp. JDM601]
Length=223

 Score =  329 bits (844),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 165/223 (74%), Positives = 185/223 (83%), Gaps = 0/223 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            ++VLVTGGDT+LGRT+AEGF   GHKVT+ G R  +LE+AAKELD +AVVCD TDP SL 
Sbjct  1    MDVLVTGGDTELGRTVAEGFSEAGHKVTIAGMRGPELEIAAKELDANAVVCDNTDPASLL  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
             ARGLFP HLDTIVNVPAP W  GDPRAYS++D A AWR ALDATVLS VLTV +VGDHL
Sbjct  61   AARGLFPHHLDTIVNVPAPRWLGGDPRAYSLADQAAAWRGALDATVLSAVLTVATVGDHL  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSIVSV+ ENP  GGA++A+KAALSNW AGQA VFGTRGIT+N VA G   + GY+G
Sbjct  121  RSGGSIVSVMPENPLDGGADAAVKAALSNWTAGQATVFGTRGITVNVVAAGAGARPGYDG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            L+  PA    EIARLA+FLTTPAARHITGQTLHVSHGALAHFG
Sbjct  181  LTSAPAGADTEIARLAVFLTTPAARHITGQTLHVSHGALAHFG  223


>gi|108799765|ref|YP_639962.1| short chain dehydrogenase [Mycobacterium sp. MCS]
 gi|119868875|ref|YP_938827.1| short chain dehydrogenase [Mycobacterium sp. KMS]
 gi|126435406|ref|YP_001071097.1| short chain dehydrogenase [Mycobacterium sp. JLS]
 gi|108770184|gb|ABG08906.1| short chain dehydrogenase [Mycobacterium sp. MCS]
 gi|119694964|gb|ABL92037.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS]
 gi|126235206|gb|ABN98606.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS]
Length=228

 Score =  310 bits (794),  Expect = 9e-83, Method: Compositional matrix adjust.
 Identities = 156/228 (69%), Positives = 182/228 (80%), Gaps = 5/228 (2%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            +EVLVTGGDTDLGRT+AEGFR+DGH+V + GARR DLE+ AKELDVD++V D TDP  + 
Sbjct  1    MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVE  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            EAR LFP HLDT+VNVPAP +   DPR +S++D A AWR ALD TVLS VLTVQ VGDHL
Sbjct  61   EARSLFPHHLDTLVNVPAPQYPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHL  120

Query  123  RSGGSIVSVVAEN-----PPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQ  177
            RSGGSIV+V+ EN        G  ++AIKAALS+W AGQA  FGTRGIT+N VA G+S  
Sbjct  121  RSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQATHFGTRGITVNAVATGKSAG  180

Query  178  TGYEGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
              Y+GLS TP  VAAEIAR+ALFL+TPAARHITGQT+HVS GALA+FG
Sbjct  181  PSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG  228


>gi|118473731|ref|YP_887922.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155]
 gi|118175018|gb|ABK75914.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155]
Length=223

 Score =  308 bits (788),  Expect = 5e-82, Method: Compositional matrix adjust.
 Identities = 151/219 (69%), Positives = 176/219 (81%), Gaps = 0/219 (0%)

Query  4    EVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTE  63
            EVLVTGGDT+LGR +A+GFR+ GH V + GARR DLEVAAKELD++++V D TD  SL  
Sbjct  3    EVLVTGGDTELGRAIAQGFRDAGHNVVIAGARRDDLEVAAKELDIESIVFDNTDAASLEA  62

Query  64   ARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLR  123
             RG FP HLDT+VNVPAP W+A DPR Y+++D A+AWRN LDATV+S  LTVQ VGDHLR
Sbjct  63   VRGQFPHHLDTLVNVPAPRWEAKDPRTYTLADLASAWRNNLDATVVSAALTVQIVGDHLR  122

Query  124  SGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEGL  183
            SGGSIV+V+ E+   G  E+AIKAALS+W AGQA  FGTRGITIN VA GRS +  Y+GL
Sbjct  123  SGGSIVNVLPESAKEGSVEAAIKAALSDWTAGQADFFGTRGITINAVAAGRSAEQAYDGL  182

Query  184  SRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALA  222
            +RTP  VA E  RLALFL+TPAARHITGQTLHVS GALA
Sbjct  183  TRTPPSVADEFTRLALFLSTPAARHITGQTLHVSRGALA  221


>gi|120404055|ref|YP_953884.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1]
 gi|119956873|gb|ABM13878.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii 
PYR-1]
Length=223

 Score =  268 bits (685),  Expect = 4e-70, Method: Compositional matrix adjust.
 Identities = 138/223 (62%), Positives = 172/223 (78%), Gaps = 0/223 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            ++VL+TG DTDLGRT+AE F   GHKV + G RR +LEV AKELDVDA+V D TDP S+ 
Sbjct  1    MDVLITGCDTDLGRTIAESFSEAGHKVLVGGRRRDELEVLAKELDVDALVFDNTDPASVA  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
               G  P HLDTI+N+PAP+W  GDPR Y+++D A  WR   DA +++ VLTVQ +GDH+
Sbjct  61   ALHGQVPAHLDTIINMPAPTWTVGDPRTYTLADHAAEWRGLFDAGLVASVLTVQVLGDHM  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSI++V+ +    G A +A+KAA+S+W AGQA  FG RGIT+N VA GR V+ GY+G
Sbjct  121  RSGGSIINVIPDFVRDGSAAAAVKAAVSDWTAGQADQFGVRGITVNAVAVGRGVEPGYDG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
            L  TP  VAAEI+RL+LFLTTPAARHITGQTLHV+HGALA+FG
Sbjct  181  LGSTPPSVAAEISRLSLFLTTPAARHITGQTLHVTHGALANFG  223


>gi|145223932|ref|YP_001134610.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK]
 gi|315444264|ref|YP_004077143.1| hypothetical protein Mspyr1_26770 [Mycobacterium sp. Spyr1]
 gi|145216418|gb|ABP45822.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum 
PYR-GCK]
 gi|315262567|gb|ADT99308.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase 
like protein [Mycobacterium sp. Spyr1]
Length=223

 Score =  262 bits (670),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 140/222 (64%), Positives = 170/222 (77%), Gaps = 0/222 (0%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            ++VLVTG DTDLGRT+AEGF   GH V + G RR +LEV AKELD DA V D TDP S+ 
Sbjct  1    MDVLVTGCDTDLGRTIAEGFHEAGHTVLVGGRRRDELEVLAKELDTDAYVFDNTDPASVG  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            +  G  P HLD I+NVPAP+W  GDPRAY+++D A  WR   DA +L+ VLTVQ +GDH+
Sbjct  61   DLHGQVPAHLDAIINVPAPTWVGGDPRAYTLTDHAAQWRGLFDANLLASVLTVQVLGDHM  120

Query  123  RSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG  182
            RSGGSI++V+ + P  GGA SA+KAA+S+W AG A  FG RGITIN VA GR V+ GY+G
Sbjct  121  RSGGSIITVIPDLPEEGGAASAVKAAVSDWTAGLANHFGIRGITINAVAVGRGVEPGYDG  180

Query  183  LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHF  224
            +  TP P + EI+RL+LFLTTPAARHITGQTLHVSHGALA+F
Sbjct  181  VGATPPPASTEISRLSLFLTTPAARHITGQTLHVSHGALANF  222


>gi|169629518|ref|YP_001703167.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977]
 gi|169241485|emb|CAM62513.1| Putative short chain dehydrogenase/reductase [Mycobacterium abscessus]
Length=227

 Score =  223 bits (567),  Expect = 2e-56, Method: Compositional matrix adjust.
 Identities = 117/221 (53%), Positives = 151/221 (69%), Gaps = 4/221 (1%)

Query  3    VEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLT  62
            ++VLVTG   ++GR +A  FRN GH+V + G    +LE+AAKEL+VDA+VCD  DP SL 
Sbjct  1    MDVLVTGAVNEVGRAVAAEFRNAGHRVVITGPNADELEIAAKELEVDAIVCDNADPDSLE  60

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            +   LFP+HLD IVN+P P W    P   +++DT  AW +  +++VL+ VLTVQ++GDHL
Sbjct  61   DNVELFPQHLDAIVNIPNPVWSEPGPHLGTLTDTGEAWLSRYESSVLTAVLTVQAIGDHL  120

Query  123  RSGGSIVSVVAENP-PAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYE  181
            RSG +I+++         GA +A KAALS W A QA   GTRGITINT+A G+S +  Y+
Sbjct  121  RSGAAIINLCTLGTRDRSGATTAAKAALSAWTAEQAERMGTRGITINTIAPGQSAEANYD  180

Query  182  GLSRTPAP---VAAEIARLALFLTTPAARHITGQTLHVSHG  219
            GL  T      VA EIARLALFL +P ARHITGQTLHVS G
Sbjct  181  GLDSTEDAHELVAGEIARLALFLASPQARHITGQTLHVSRG  221


>gi|294816238|ref|ZP_06774881.1| oxidoreductase [Streptomyces clavuligerus ATCC 27064]
 gi|326444568|ref|ZP_08219302.1| short-chain dehydrogenase/reductase SDR [Streptomyces clavuligerus 
ATCC 27064]
 gi|294328837|gb|EFG10480.1| oxidoreductase [Streptomyces clavuligerus ATCC 27064]
Length=247

 Score =  112 bits (281),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 91/248 (37%), Positives = 127/248 (52%), Gaps = 33/248 (13%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            M  ++L+TGG T +GR +A  F + G +V + G R G L   A+E    A VCD TDP +
Sbjct  1    MTRDILITGGGTGIGRALARHFADAGDRVVVTGRRPGPLAAVARETGARAAVCDHTDPVA  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDP--------RAYSVSDTANAWRNALDATVLSVV  112
            LT      P  LD +VN    + D  DP         A  ++  A A+R  LDA +L+ V
Sbjct  61   LTALLAELPATLDVLVNNAGGNTDFTDPGPVTGLEGTAAELALCARAFRANLDANLLTAV  120

Query  113  LTVQSVGDHLRSGGSIVSV--VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTV  170
            LT ++VGD L  GG+++ +  +A +  A G+  A KAAL+ W    AA  G R IT N V
Sbjct  121  LTTRAVGDRLAPGGAVIQIGSIAADQGA-GSYGAAKAALTTWNLDLAAELGARDITANVV  179

Query  171  ACGRSVQTGY------------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQ  212
            + G + +T +                   G + TP  +AA +     FL +P ARHITGQ
Sbjct  180  SPGYTGETEFFRDRLSDTRRESLVAATATGRAGTPQDIAAAVG----FLASPGARHITGQ  235

Query  213  TLHVSHGA  220
             LHV+ GA
Sbjct  236  VLHVNGGA  243


>gi|254391842|ref|ZP_05007036.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces clavuligerus 
ATCC 27064]
 gi|197705523|gb|EDY51335.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces clavuligerus 
ATCC 27064]
Length=242

 Score =  112 bits (281),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 84/233 (37%), Positives = 116/233 (50%), Gaps = 33/233 (14%)

Query  16   RTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTI  75
            R +A  F + G +V + G R G L   A+E    A VCD TDP +LT      P  LD +
Sbjct  11   RALARHFADAGDRVVVTGRRPGPLAAVARETGARAAVCDHTDPVALTALLAELPATLDVL  70

Query  76   VNVPAPSWDAGDP--------RAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGS  127
            VN    + D  DP         A  ++  A A+R  LDA +L+ VLT ++VGD L  GG+
Sbjct  71   VNNAGGNTDFTDPGPVTGLEGTAAELALCARAFRANLDANLLTAVLTTRAVGDRLAPGGA  130

Query  128  IVSV--VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY-----  180
            ++ +  +A +  A G+  A KAAL+ W    AA  G R IT N V+ G + +T +     
Sbjct  131  VIQIGSIAADQGA-GSYGAAKAALTTWNLDLAAELGARDITANVVSPGYTGETEFFRDRL  189

Query  181  -------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
                          G + TP  +AA +     FL +P ARHITGQ LHV+ GA
Sbjct  190  SDTRRESLVAATATGRAGTPQDIAAAVG----FLASPGARHITGQVLHVNGGA  238


>gi|312197069|ref|YP_004017130.1| short-chain dehydrogenase/reductase SDR [Frankia sp. EuI1c]
 gi|311228405|gb|ADP81260.1| short-chain dehydrogenase/reductase SDR [Frankia sp. EuI1c]
Length=244

 Score =  107 bits (267),  Expect = 1e-21, Method: Compositional matrix adjust.
 Identities = 81/239 (34%), Positives = 118/239 (50%), Gaps = 20/239 (8%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKEL--DVDAVVCDTTDP  58
            M+  V+++GG T +GR++A  F  +G++V ++G R   L  AA EL   V  VVCD  DP
Sbjct  1    MSRSVVISGGGTGIGRSIARSFVENGNEVVIIGRRAAVLNTAATELGDRVRPVVCDLADP  60

Query  59   TSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSV  118
             ++  A    P  +D +VN    +     PR  S+++    W   + A +L+ V    +V
Sbjct  61   VAVQRALIELPARIDVLVNAAGANLATRTPRPDSLAEVVALWEGQVRANLLTTVALTCAV  120

Query  119  GDHLRSGGSIVSVVAENPPAGGAES----AIKAALSNWIAGQAAVFGTRGITINTVACGR  174
             D L  GG IV   +    +GG  S      KAA+  W  G +A  G+RGIT+N VA G 
Sbjct  121  LDRLGPGGRIVGFSSGAARSGGPHSYGYGVAKAAVEAWARGLSAEVGSRGITVNAVAPGL  180

Query  175  SVQTGY-------EGLSR-------TPAPVAAEIARLALFLTTPAARHITGQTLHVSHG  219
            +  T +       E  +R         A    ++A   LFLT+P A HI+GQTL V  G
Sbjct  181  TDGTEFFPADVDDETRARLVARADNRRAGTTGDVAAAVLFLTSPDAGHISGQTLAVDGG  239


>gi|256396641|ref|YP_003118205.1| short-chain dehydrogenase/reductase SDR [Catenulispora acidiphila 
DSM 44928]
 gi|256362867|gb|ACU76364.1| short-chain dehydrogenase/reductase SDR [Catenulispora acidiphila 
DSM 44928]
Length=239

 Score =  107 bits (266),  Expect = 2e-21, Method: Compositional matrix adjust.
 Identities = 84/240 (35%), Positives = 116/240 (49%), Gaps = 23/240 (9%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            M   VLVTGG + +GR +A  F  DG  V + G R   +E  A+E+    VVCD TDP +
Sbjct  1    MTRTVLVTGGSSGIGRAVAARFVADGADVVVTGRRAQLVETTAQEIGAAGVVCDATDPQA  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPR--AYSVSDTANAWRNALDATVLSVVLTVQSV  118
            +      F   LD +VN  A    +  PR  A ++      W+  LD  +LS VLT  ++
Sbjct  61   VEALAARFD-TLDVLVNA-AGGLGSAQPRPGAGALETVLAEWQADLDGNLLSAVLTTTAL  118

Query  119  GDHLRSGGSIVSV-VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQ  177
               L  GG+ +++    +   GG+  A KAAL+ W A  +A  G RG+T N V+ G    
Sbjct  119  KPVLAPGGTAIAIGTIGSERRGGSYGAAKAALTAWYAMLSADLGPRGVTANVVSPGYIAD  178

Query  178  TGY----------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGAL  221
            TG+                    R  AP   +IA    FL +P AR ITGQT+HV+ GA 
Sbjct  179  TGFFRGAMTDAREQTLIAETHTKRAGAP--HDIAETVFFLASPGARQITGQTIHVNGGAF  236


>gi|134100225|ref|YP_001105886.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|291006553|ref|ZP_06564526.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133912848|emb|CAM02961.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Saccharopolyspora 
erythraea NRRL 2338]
Length=238

 Score =  103 bits (257),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 81/232 (35%), Positives = 109/232 (47%), Gaps = 15/232 (6%)

Query  4    EVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTE  63
            +++VTG  + +G  +AE F   G  VT+ G R   L  AA  L   AV  D TDP ++  
Sbjct  3    QIVVTGAGSGIGYAIAEHFAASGDAVTITGRRPEVLHRAADTLGARAVPFDATDPDAVEA  62

Query  64   ARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLR  123
            A    P H+D +VN    + D   P    +   A  W   L + VLS VL   ++   L 
Sbjct  63   ALESLPDHVDVVVNNAGANTDFERPEPDGLRALAQQWEANLASNVLSAVLVTAALTPRLT  122

Query  124  SGGSIVSVVAENPPAG-GAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY--  180
             G  +V++ +     G G+  A KAA+  W A  A   G RGIT N +A G +  TG+  
Sbjct  123  DGARVVTIGSIAARQGAGSYGAAKAAVEAWTADLAGQLGPRGITANVIAPGLTEHTGFFQ  182

Query  181  EGL------------SRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
             GL                A   A+IA L  FL +P A HITGQ LHV+ GA
Sbjct  183  NGLPDHVRQTLVAATRNQRAGTPADIAALTGFLASPQAGHITGQVLHVNGGA  234


>gi|284031480|ref|YP_003381411.1| short-chain dehydrogenase/reductase SDR [Kribbella flavida DSM 
17836]
 gi|283810773|gb|ADB32612.1| short-chain dehydrogenase/reductase SDR [Kribbella flavida DSM 
17836]
Length=238

 Score =  102 bits (254),  Expect = 4e-20, Method: Compositional matrix adjust.
 Identities = 88/245 (36%), Positives = 113/245 (47%), Gaps = 34/245 (13%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGD-LEVAAKELDVDAVVCDTTDPT  59
            MA  ++VTGG T +GR  AE FR DG  V + G RRGD L   A EL   A+VCD  DP 
Sbjct  1    MARTIVVTGGATGIGRATAERFRADGDDVVITG-RRGDVLTRTADELGAKAIVCDAADPA  59

Query  60   SLTEARGLFPRHLDTIVNVPAPSWDAGDPRA-YSVSDTANAWRNALDATVLSVVLTVQSV  118
             +       P  +D +VN    + D   P A   +      W    +A VLS VLT  ++
Sbjct  60   QVAAFAEQLPGRIDVLVNNAGGNTDLETPAAGDDLQRLRRNWLANYEANVLSAVLTTSAL  119

Query  119  GDHLRSG----GSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGR  174
               L +     GSI          GG+  A K+AL+ W    AA  G RG+T N VA G 
Sbjct  120  AARLTTAVIHLGSIAGT-----RGGGSYGAAKSALATWSLEVAAELGPRGVTSNVVAPGY  174

Query  175  SVQTGY------------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHV  216
            +  T +                     + TPA VAA I     F+ +P A H+TGQ LHV
Sbjct  175  TADTEFFRDQLTDERRTWLLDSTMTKRAGTPADVAAVIH----FVASPQAGHVTGQVLHV  230

Query  217  SHGAL  221
            + GAL
Sbjct  231  NGGAL  235


>gi|291302433|ref|YP_003513711.1| short-chain dehydrogenase/reductase SDR [Stackebrandtia nassauensis 
DSM 44728]
 gi|290571653|gb|ADD44618.1| short-chain dehydrogenase/reductase SDR [Stackebrandtia nassauensis 
DSM 44728]
Length=241

 Score = 99.0 bits (245),  Expect = 5e-19, Method: Compositional matrix adjust.
 Identities = 73/224 (33%), Positives = 108/224 (49%), Gaps = 21/224 (9%)

Query  16   RTMAEGFRNDGHKVTLVGARRGDLEVAAKEL--DVDAVVCDTTDPTSLTEARGLFPRHLD  73
            R +A  F   G  V + G R+  L+    +L  D+ A+ CD TDP  L       P  +D
Sbjct  16   RAVAARFAEAGDSVVITGRRQAVLDKTVADLGGDIRAITCDHTDPEQLAALAAALPERVD  75

Query  74   TIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIVSVVA  133
             +VN    + D G      ++    AW   LD  ++S  LT +++G+ L SGGS++ + +
Sbjct  76   VLVNNAGGNTDIGTETPSGLAGLGRAWLANLDTNLISAALTTEAIGERLGSGGSVIHIGS  135

Query  134  ENPPAG-GAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEG----------  182
                 G G   A KA L++W  G A   GTR IT N ++ G   +T + G          
Sbjct  136  IAADKGNGFYGAAKAGLASWNIGLARELGTRDITSNVISPGYISETEFFGDVMTEQRRAA  195

Query  183  ------LSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
                  + R   P  A+IA  A FL +P AR++TGQTL+V+ GA
Sbjct  196  LIEATFVKRVGIP--ADIAGAAWFLASPDARYVTGQTLNVNGGA  237


>gi|226308780|ref|YP_002768740.1| oxidoreductase [Rhodococcus erythropolis PR4]
 gi|226187897|dbj|BAH36001.1| putative oxidoreductase [Rhodococcus erythropolis PR4]
Length=241

 Score = 98.6 bits (244),  Expect = 7e-19, Method: Compositional matrix adjust.
 Identities = 82/236 (35%), Positives = 112/236 (48%), Gaps = 17/236 (7%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKEL--DVDAVVCDTTDP  58
            M   VLVTGG T +GR +A  F  DG  V + G R   LE  A+EL  DV A+ CD +DP
Sbjct  1    MTRTVLVTGGGTGIGRAVAAAFARDGDTVFVTGRRTEPLEKTAEELGSDVHALTCDNSDP  60

Query  59   TSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSV  118
              L   +   P  +D +V+    + D        +   A  WR  LD+ ++S VLT  +V
Sbjct  61   KDLKRLQDSLPGTIDVVVHCAGGNTDFDREAPSDLESLAAGWRANLDSNLISAVLTTAAV  120

Query  119  GDHLRSGGSIVSVVA-ENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQ  177
             D + SGG+++++ +       GA  A KAA++ W    AA  G  GIT N V+ G    
Sbjct  121  RDRIPSGGAVITIGSIAADKGAGAYGAAKAAVATWNIDLAAELGPEGITANIVSPGYIAD  180

Query  178  TGY--------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHG  219
            T +              E  S   A    +IA    FL +P AR ITGQ L V+ G
Sbjct  181  TEFFRDFLTDERRAMLIESTSTKRAGTPDDIASAVHFLASPGARQITGQVLAVNGG  236


>gi|302545655|ref|ZP_07297997.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302463273|gb|EFL26366.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Streptomyces himastatinicus 
ATCC 53653]
Length=239

 Score = 97.4 bits (241),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 85/239 (36%), Positives = 114/239 (48%), Gaps = 23/239 (9%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            M+  +L+TGG T +GR +A  F   G  V + G R G L+  A E  V A+VCD T+P +
Sbjct  1    MSRNILITGGGTGIGRAVARHFAERGEHVIVTGRRPGPLKELADEAGVHALVCDHTEPEA  60

Query  61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            L       P  LD +VN    + D        ++  A  +R  LDA ++S  LT Q V  
Sbjct  61   LVGLPAELPDRLDVLVNNAGGNTDFDADGKSDLASYARDFRANLDANLVSAALTTQCVDG  120

Query  121  HLRSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQ  177
             L SGG++V   S+ A+     GA  A KA L+ W    A   G RGIT N V+ G    
Sbjct  121  RLASGGAVVHIGSIAADQ--GAGAYGASKAGLAAWNVDLAGRLGPRGITANVVSPGYIAD  178

Query  178  TGY----------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
            T +                    R  +P   +IA    FL +PAARHITGQ L+V+ GA
Sbjct  179  TEFFRDQLTDERREWLIASTATGRPGSPT--DIAEAVAFLASPAARHITGQVLNVNGGA  235


>gi|229489268|ref|ZP_04383134.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Rhodococcus erythropolis 
SK121]
 gi|229324772|gb|EEN90527.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Rhodococcus erythropolis 
SK121]
Length=241

 Score = 95.5 bits (236),  Expect = 5e-18, Method: Compositional matrix adjust.
 Identities = 80/236 (34%), Positives = 111/236 (48%), Gaps = 17/236 (7%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKEL--DVDAVVCDTTDP  58
            M   VLVTGG T +GR +A  F  DG  V + G R   LE  A+EL  +V A+ CD +DP
Sbjct  1    MTRTVLVTGGGTGIGRAVAAAFARDGDTVFVTGRRTETLEKTAEELGDNVHALTCDNSDP  60

Query  59   TSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSV  118
              L   +   P  +D + +    + D        +   A  WR  LD+ ++S VLT  +V
Sbjct  61   KDLKRLQDSLPGTIDVVAHCAGGNTDFDREAPSDLESLAAGWRANLDSNLISAVLTTAAV  120

Query  119  GDHLRSGGSIVSVVA-ENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQ  177
             D + SGG+++++ +       GA  A KAA++ W    AA  G  GIT N V+ G    
Sbjct  121  RDRIPSGGAVITIGSIAADKGAGAYGAAKAAVATWNVDLAAELGPEGITANIVSPGYIAD  180

Query  178  TGY--------------EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHG  219
            T +              E  S   A    +IA    FL +P AR ITGQ L V+ G
Sbjct  181  TEFFRDFLTDERRAMLIESTSTKRAGTPDDIASAVHFLASPGARQITGQVLAVNGG  236


>gi|332669331|ref|YP_004452339.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 
484]
 gi|332338369|gb|AEE44952.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 
484]
Length=237

 Score = 86.7 bits (213),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 78/242 (33%), Positives = 108/242 (45%), Gaps = 31/242 (12%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS  60
            MA +VL+TGG   +GR  A  F   G  V LV  R  D+   A+++    +  D  DP S
Sbjct  1    MARQVLITGGTRGIGRATAARFVALGDDV-LVTGRGPDVAATARQVGARGIRLDLEDPES  59

Query  61   LTEARGLFPRHLDTIVNV-----PAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTV  115
            +   R         + N      P P   AG      ++D A  W   L   ++  VL V
Sbjct  60   VGTLRDDLDAVDVVVNNAGGFVGPPPPAGAG------LADVAAHWHRGLAVNLVGAVLVV  113

Query  116  QSVGDHLRSGGSIVSVVAENPP-AGGAESAIKAALSNWIAGQAAVFGTRGITINTVACG-  173
             ++ D LR+GG++VSV +     AG   S  KAAL  W  G +   G R +T+N VA G 
Sbjct  114  TALEDRLRAGGAVVSVGSIGAEYAGNPYSVAKAALQAWSVGLSERLGPRDVTVNAVAPGY  173

Query  174  ---------------RSVQTGYEGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSH  218
                           R    G   L R   P   ++A   +FL +  ARH+TGQT+HV+ 
Sbjct  174  VEGTDLFGGPLDAERRRTLVGRTSLGRPATP--EDVAGTVVFLASADARHLTGQTVHVNG  231

Query  219  GA  220
            GA
Sbjct  232  GA  233


>gi|271962845|ref|YP_003337041.1| short chain dehydrogenase protein [Streptosporangium roseum DSM 
43021]
 gi|270506020|gb|ACZ84298.1| short chain dehydrogenase protein [Streptosporangium roseum DSM 
43021]
Length=240

 Score = 85.5 bits (210),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 81/238 (35%), Positives = 116/238 (49%), Gaps = 25/238 (10%)

Query  4    EVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTE  63
            E++VTGG T +G  +A  F   G +VT+ G R   L+  A  L V  V  +  +P ++ E
Sbjct  3    EIVVTGGGTGIGAAVAAAFAAHGDRVTITGRREQVLKETADRLGVSHVAFNAANPVAVGE  62

Query  64   ARGLFPRHLDTIVNVPAPSWDAGD-PRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHL  122
            A    P  +D +VN    + +    P    + D A +W   L+A ++S VL   ++   L
Sbjct  63   ALERLPDRVDVLVNNAGGNTNLDRAPDGDDLMDVAESWWANLNANLMSAVLVTSALTPRL  122

Query  123  RSGGSIVSV--VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
              GG IV++  +A      G+  A KAA+  W A  AA  G RG+T N V+ G  V T +
Sbjct  123  ADGGRIVTIGSIAARGTGSGSYGAAKAAVEAWTADLAAELGPRGVTANVVSPGLVVDTEF  182

Query  181  -------EGLSR-----------TPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
                   EG+ R           TP  VAA +     FL +P ARHITGQ +HV+ GA
Sbjct  183  FRGRLTEEGVRRRVESTRNGRPGTPDDVAATVR----FLASPEARHITGQVVHVNGGA  236


>gi|222108964|ref|YP_002551230.1| short chain dehydrogenase protein [Agrobacterium radiobacter 
K84]
 gi|221727886|gb|ACM30936.1| short chain dehydrogenase protein [Agrobacterium radiobacter 
K84]
Length=250

 Score = 82.8 bits (203),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 71/236 (31%), Positives = 109/236 (47%), Gaps = 36/236 (15%)

Query  16   RTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTI  75
            R  A  F  +G+KV + G R+  LE +A  L V+AV  D +DP ++  A    P  +D +
Sbjct  16   RACAAHFAAEGNKVIITGRRKEVLEESAASLGVEAVAFDASDPFAVAAALEKLPTSVDVL  75

Query  76   VNVPAPSWD-----------AGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRS  124
            +N    + D           A +P+   + + A+ W+   +A VLS VL  +++   L  
Sbjct  76   INNAGGNTDLSHAALSTAISAPEPQGR-LEEIASRWQANFEANVLSAVLVTEALAARLTD  134

Query  125  GGSIVSV--VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACG---------  173
               I+++  +A     GG+  A KAA+  W A  A   G+RGIT N VA G         
Sbjct  135  NARIITIGSIAGRTGGGGSYGAAKAAIEAWTADLARSLGSRGITANVVAPGLIESTEFFQ  194

Query  174  ---------RSVQTGYEGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
                     R V+  +   +  P  V A +A    FL  P+A H+TGQ + V+ GA
Sbjct  195  GRLADERRARLVEATFTKRAGQPKDVVAAVA----FLALPSAGHVTGQVIPVNGGA  246


>gi|326334087|ref|ZP_08200315.1| 3-oxoacyl-acyl carrier protein reductase [Nocardioidaceae bacterium 
Broad-1]
 gi|325948138|gb|EGD40250.1| 3-oxoacyl-acyl carrier protein reductase [Nocardioidaceae bacterium 
Broad-1]
Length=240

 Score = 82.4 bits (202),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 83/242 (35%), Positives = 110/242 (46%), Gaps = 32/242 (13%)

Query  6    LVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELD-------VDAVVCDTTDP  58
            +VTGG T LGR +A+    DG +VT+VG R   LE A KE++       V  VV D  DP
Sbjct  1    MVTGGGTGLGRAIADRLAADGLEVTIVGRRAEVLETATKEINAAVGADQVTYVVADCADP  60

Query  59   TSLTEARGLFPRHLDTIV-NVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQS  117
              +       P  +D +V N    +   GD     +   A+ W       VL+ VL V++
Sbjct  61   GDVRALADACPDRVDVLVLNAGGLTPSTGD----DLEALAHDWAADYRLNVLTAVLPVEA  116

Query  118  VGDHL-RSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACG  173
            +   L R GG IV   S+ A   P  G+  A K A++ WI G AA     GIT N VA G
Sbjct  117  LLPRLARPGGRIVAMSSIAALRGP--GSYGASKGAINTWITGLAAEVAADGITANAVAPG  174

Query  174  RSVQTGYEGLSRTPAPVAA--------------EIARLALFLTTPAARHITGQTLHVSHG  219
                T +    R+P  +A               EIA L   LT+P A   TGQ + +  G
Sbjct  175  FVPDTEFWDSRRSPELIAQRTSQIPVGRPGAPEEIAALVAHLTSPDAGFTTGQVVGIHGG  234

Query  220  AL  221
            AL
Sbjct  235  AL  236


>gi|159036112|ref|YP_001535365.1| short-chain dehydrogenase/reductase SDR [Salinispora arenicola 
CNS-205]
 gi|157914947|gb|ABV96374.1| short-chain dehydrogenase/reductase SDR [Salinispora arenicola 
CNS-205]
Length=248

 Score = 77.4 bits (189),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 73/223 (33%), Positives = 104/223 (47%), Gaps = 29/223 (13%)

Query  25   DGHKVTLVGARRGDLEVAAKELDVD--------AVVCDTTDPTSLTE-ARGLFPRHLDTI  75
            DG  V +VG R   L      +  D        AVV D  DP  ++  A  +  R +D +
Sbjct  26   DGFDVLVVGRREEALRATTARISWDIARPGAVRAVVADLADPEQVSRVAETVEGRAVDAV  85

Query  76   VNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGS---IVSVV  132
            +N  A S+  GD  + +++  A+ WR  LDA +L+ VL  +++   LR  G    +VS +
Sbjct  86   IN-NAGSYRGGD--SGTLAGVAHQWRANLDANILTAVLLTEALRPALRRPGGRVILVSSI  142

Query  133  AENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTPA----  188
            A     GG  SA KAAL  W    AA  G   IT+N V+ G    T + G   TP     
Sbjct  143  AAQQGGGGPYSAAKAALHGWAYDLAAQLGPEQITVNVVSPGYVTDTEFFGGRMTPQGHAR  202

Query  189  PVAA----------EIARLALFLTTPAARHITGQTLHVSHGAL  221
             VAA          +IA    +L  PAA ++TGQ L V+ G++
Sbjct  203  RVAATLVGRAGTPDDIAEAVRYLAGPAAGYVTGQVLGVNGGSV  245


>gi|337765846|emb|CCB74555.1| conserved protein of unknown function [Streptomyces cattleya 
NRRL 8057]
Length=255

 Score = 76.3 bits (186),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 73/236 (31%), Positives = 103/236 (44%), Gaps = 33/236 (13%)

Query  12   TDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKE------LDVDAVVCDTTDPTSLTEAR  65
            T +GR +AE F   G ++ +VG RR  L  AA E      L V  + CD  DP  +  A 
Sbjct  24   TGIGRAIAERFAAAGDRLVIVGRRREVLRTAADEISAAHGLAVTPITCDLADPDDVEAAL  83

Query  66   GLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANA----WRNALDATVLSVVLTVQSVGDH  121
               P  +D +VN      +AG  R  +V    +     WR   +  VL+ VL  +SV D 
Sbjct  84   ARLPERIDVLVN------NAGS-REVAVGAGPHGILARWRGDFERNVLTAVLVTESVKDR  136

Query  122  L-RSGGSIVSVVAENP-PAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTG  179
            L R  G +++V +      GG+  A KAAL  W    AA  G +G+T N VA G    T 
Sbjct  137  LTRDRGRVITVTSLAALRGGGSYGASKAALHAWNHSLAAQLGPQGVTCNVVAPGTVAGTE  196

Query  180  YEGLSRTPAPVA--------------AEIARLALFLTTPAARHITGQTLHVSHGAL  221
            + G     A +                ++A   +FL +  A  ITG+ L  + G L
Sbjct  197  FFGARLNEAELTRRAGRTLVGRVGRPGDVAAAVVFLASEEAGFITGEILQCNGGEL  252


>gi|302540248|ref|ZP_07292590.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces 
hygroscopicus ATCC 53653]
 gi|302457866|gb|EFL20959.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces 
himastatinicus ATCC 53653]
Length=251

 Score = 75.5 bits (184),  Expect = 6e-12, Method: Compositional matrix adjust.
 Identities = 81/252 (33%), Positives = 113/252 (45%), Gaps = 41/252 (16%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDV---DAVV----C  53
            M   ++V+GG T +G   AE F  DG +V +VG R   L  AA +L+    D +V     
Sbjct  5    MGRRIVVSGGGTGIGLATAESFAADGDRVVIVGRRTEVLRAAADKLNATHGDGLVTWTAA  64

Query  54   DTTDPTSLTEARGLFPRH--LDTIV-----NVPAPSWDAGDPRAYSVSDTANAWRNALDA  106
            D +DP     A         +D IV     NV AP  D       ++   A+ ++    A
Sbjct  65   DLSDPGQTRRAADEIAADGPVDVIVTNAGGNV-APGNDG------TLEGIADQYQRNFAA  117

Query  107  TVLSVVLTVQSVGDHL-RSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGT  162
             VL+ VL  +++  H+ R GG IV   SV A   P  G+    KAAL  +    A   G 
Sbjct  118  NVLTAVLLTEALIPHIARPGGRIVHLSSVAALRGP--GSYGGTKAALHTYTFELAKRLGA  175

Query  163  RGITINTVACGRSVQTGYEGLSRTPAPVA--------------AEIARLALFLTTPAARH  208
             G+T N VA G    T + G   TP  +A              AEIA    +L +P A +
Sbjct  176  EGVTANAVAPGYVEDTEFFGERGTPEFIAQQIGQTLTGQPGVPAEIAAAIRYLASPEAAY  235

Query  209  ITGQTLHVSHGA  220
            +TGQ LH++ GA
Sbjct  236  VTGQVLHINGGA  247


>gi|145592940|ref|YP_001157237.1| short-chain dehydrogenase/reductase SDR [Salinispora tropica 
CNB-440]
 gi|145302277|gb|ABP52859.1| short-chain dehydrogenase/reductase SDR [Salinispora tropica 
CNB-440]
Length=280

 Score = 75.1 bits (183),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 71/223 (32%), Positives = 99/223 (45%), Gaps = 29/223 (13%)

Query  25   DGHKVTLVGARRGDLEVAAKELDVD--------AVVCDTTDPTSLTEA-RGLFPRHLDTI  75
            DG  V +VG R   L      L  D        AVV D TDP  +      +  R +D +
Sbjct  58   DGFDVLVVGRREDALRATTARLSWDLARPGAVRAVVADLTDPQQVPRVVEAVDGRAVDAV  117

Query  76   VNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGS---IVSVV  132
            VN  A  +  G+P   +++  A  WR +L+A +L+ VL  +++   LR  G    +VS  
Sbjct  118  VN-NAGGYLGGEPD--TLAGVAEQWRASLEANLLTAVLLTEALRPTLRRPGGRVILVSSA  174

Query  133  AENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTP-----  187
            A     GG  SA KAAL  W    A   G   +T+N V+ G  V T + G  RTP     
Sbjct  175  AAQQGGGGPHSAAKAALHGWAYDLAVRLGPDQVTVNVVSPGYVVDTEFFGGRRTPEGHAR  234

Query  188  ---------APVAAEIARLALFLTTPAARHITGQTLHVSHGAL  221
                     A    +IA    +L  PAA ++TGQ L V  G++
Sbjct  235  RVAATLVGRAGTPDDIAAAVRYLAGPAAGYVTGQVLGVDGGSV  277


>gi|311898812|dbj|BAJ31220.1| putative oxidoreductase [Kitasatospora setae KM-6054]
Length=239

 Score = 74.7 bits (182),  Expect = 8e-12, Method: Compositional matrix adjust.
 Identities = 76/226 (34%), Positives = 103/226 (46%), Gaps = 29/226 (12%)

Query  18   MAEGFRNDGHKVTLVGARRGDLEVAAKEL--DVDAVVCDTTDPTSLTEARGLFPRHLDTI  75
            +A  F   G +V +VG R G L+ AA+E+  +V  +VCD  DP ++  A    P  +D +
Sbjct  18   VARRFAEAGERVVIVGRRPGVLDQAAQEIGTNVTPLVCDLADPDAVEAALPALPARIDVL  77

Query  76   VNVPAPSWDAGDPRAYSVSDTANA----WRNALDATVLSVVLTVQSVGDHLRSG-GSIVS  130
            VN      +AG  R   +    +A    WR   +  VL+ VL  +SV D L  G G +V+
Sbjct  78   VN------NAGS-RETVLGAGPHAVLARWRGDFERNVLTAVLLTESVRDRLTPGSGRVVT  130

Query  131  VVAENPPAG-GAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTPAP  189
            V +     G G+  A KA+L  W    AA  G  GIT N VA G    T + G     A 
Sbjct  131  VSSIAALRGAGSYGAAKASLHAWNHFLAAQLGPSGITANIVAPGTVAGTEFFGPRLDDAE  190

Query  190  VAAEIARLAL--------------FLTTPAARHITGQTLHVSHGAL  221
            VA   AR  L              FL +  A  ITG+ LH + G L
Sbjct  191  VARRSARTLLGRIGESGEVAAAVCFLASAEAGFITGEILHCNGGEL  236


>gi|297155572|gb|ADI05284.1| Putative 3-oxacyl-ACP reductase [Streptomyces bingchenggensis 
BCW-1]
Length=247

 Score = 74.3 bits (181),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 81/257 (32%), Positives = 113/257 (44%), Gaps = 43/257 (16%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELD-------VDAVVC  53
            M   ++V+GG T +G   AE F  DG +V +VG R   L  AA++++       V     
Sbjct  1    MGRRIVVSGGGTGIGLATAESFAADGDRVVIVGRRAEVLRAAAEKVNAATGADLVTWTSA  60

Query  54   DTTDPTSLTEARGLFPRH--LDTIV-----NVPAPSWDAGDPRAYSVSDTANAWRNALDA  106
            D +DP     A         +D +V     NV AP  D       ++   A+ ++    A
Sbjct  61   DLSDPEQTRSAAEFIAADGPVDVVVTNAGGNV-APGNDG------TLEGIADQFQRNFSA  113

Query  107  TVLSVVLTVQSVGDHL-RSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGT  162
             VL+ VL  +++  HL R GG IV   SV A   P  G+    KA L  +    A   G 
Sbjct  114  NVLTAVLLTEALLPHLTRPGGRIVHLSSVAALRGP--GSYGGTKAHLHVYTYDLAKRLGA  171

Query  163  RGITINTVACGRSVQTGYEGLSRTPAPVA--------------AEIARLALFLTTPAARH  208
             GIT N VA G    T + G   TP  +A              AEIA    +L +P A +
Sbjct  172  EGITANAVAPGYVQDTEFFGERGTPEFIAQQIGQTLTGQPGYPAEIAAAIRYLASPEAAY  231

Query  209  ITGQTLHVSHGALAHFG  225
            +TGQ LH++ G  A FG
Sbjct  232  VTGQVLHINGG--AQFG  246


>gi|316305717|gb|ADU56362.1| 3-oxoacyl-ACP reductase [Streptomyces sp. ATCC 55098]
Length=220

 Score = 74.3 bits (181),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 68/220 (31%), Positives = 97/220 (45%), Gaps = 24/220 (10%)

Query  28   KVTLVGARRGDLEVAAKELD--VDAVVCDTTDPTSLTEARGLFPRHLDTIVNVP--APSW  83
            +V + G R   LE  A EL   V  +  D +DP ++  A    P  +D +VN    A  +
Sbjct  2    EVVITGRRAEILERTAAELGPLVTPLAFDASDPAAVEAALPQLPDRVDVLVNNAGGATEY  61

Query  84   DAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIV---SVVAENPPAGG  140
            D   P    + +   AW   +DA +++ VL   ++   +  GGSIV   S+ A    A G
Sbjct  62   DHAMPPREQLKELREAWLRNIDANLMTAVLMTSALEPRIPDGGSIVVIGSIAARGFGASG  121

Query  141  -AESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTG--------------YEGLSR  185
                  KAAL  W    A   G RGI++N V+ G +V                  E  + 
Sbjct  122  YGYGPAKAALEPWATDLAHELGARGISVNVVSPGFTVSNDRARDFVASGDASPLIESGAT  181

Query  186  TPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG  225
              A    ++A +  FLTTPAA   TGQT+HV+ G   H G
Sbjct  182  KRATEVDDVAAMVAFLTTPAAAQTTGQTIHVNGG--THLG  219


>gi|302530269|ref|ZP_07282611.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces sp. 
AA4]
 gi|302439164|gb|EFL10980.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces sp. 
AA4]
Length=238

 Score = 73.9 bits (180),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 68/213 (32%), Positives = 92/213 (44%), Gaps = 21/213 (9%)

Query  26   GHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDA  85
            G +VT+ G R   L  AA  L   AV  D +DP ++  A    P  +D +VN    + D 
Sbjct  26   GDQVTITGRREDVLTEAASLLGARAVSFDASDPEAVEAALDQLPERVDVLVNNAGGNTDF  85

Query  86   GDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAG--GAES  143
                +  +     AW   L A + S      ++ D L   G IV++      AG  GAES
Sbjct  86   LHADSGGLKALDAAWTANLRANLFSAAFVTTALKDRLADNGRIVTI---GSIAGHTGAES  142

Query  144  A--IKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY--------------EGLSRTP  187
                KAA+  W    A  FG RGIT N VA G  V T +              E      
Sbjct  143  YGWAKAAVEVWNTETARQFGPRGITANIVAPGLIVDTEFFRGKLSAERQEWLVENTMTKR  202

Query  188  APVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
            A    ++A +  FL +P A H+TGQ +HV+ GA
Sbjct  203  AGKPDDVAEVVRFLASPEAGHVTGQVVHVNGGA  235


>gi|238025266|ref|YP_002909498.1| putative 3-oxacyl-ACP reductase [Burkholderia glumae BGR1]
 gi|237879931|gb|ACR32263.1| Putative 3-oxacyl-ACP reductase [Burkholderia glumae BGR1]
Length=256

 Score = 73.2 bits (178),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 78/260 (30%), Positives = 111/260 (43%), Gaps = 48/260 (18%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKEL--------DVDAVV  52
            M+  V+V+GG T +G   A  F   G +V +VG R   L  A  E+         V  + 
Sbjct  1    MSETVVVSGGGTGIGLAAARYFARRGAQVVIVGRRETVLARAVDEIAQAAPGAPRVLPLR  60

Query  53   CDTTDPTSLTEARGLFP---RHLDTIVNVPA-------PSWDAGDPRAYSVSDTANAWRN  102
             D ++P  +   R       R +D +VN          P+ D  D     ++  A  W +
Sbjct  61   ADLSEPAQVESLRDALVERFRTVDVLVNAAGGHVLRQRPASDYAD----GLAGVARRWTD  116

Query  103  ALDATVLSVVLTVQSVGDHL-RSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAA  158
             L    LS VL  +++  HL + GG IV   S+ A      G   A KAAL  + A  A 
Sbjct  117  NLRMNTLSAVLLTEALVPHLSKPGGRIVLVSSIAAFRGSGQGCYGASKAALHPYCADLAK  176

Query  159  VFGTRGITINTVACGRSVQTGY------------------EGLSRTPAPVAAEIARLALF  200
              G +G+T+NTVA G  V T +                   G + TP  +A  I     +
Sbjct  177  ALGPKGVTVNTVAPGFVVDTEFFGGALNERQRQDKIAEAVNGRAGTPDDIANTIG----W  232

Query  201  LTTPAARHITGQTLHVSHGA  220
            L +P A HITGQ +HV+ GA
Sbjct  233  LASPEALHITGQVIHVNGGA  252


>gi|300783255|ref|YP_003763546.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
U32]
 gi|299792769|gb|ADJ43144.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
U32]
 gi|340524636|gb|AEK39841.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
S699]
Length=242

 Score = 73.2 bits (178),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 69/214 (33%), Positives = 97/214 (46%), Gaps = 22/214 (10%)

Query  26   GHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWD-  84
            G +VT+ G R+  LE AA+E+   AV  D +DP ++  A    P  +D +VN    + D 
Sbjct  28   GERVTVTGRRKDVLEAAAEEIGARAVAFDASDPAAVQAALAELPARVDVLVNNAGGNTDR  87

Query  85   -AGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAG-GAE  142
                P A  +   A+AW+   +A VLS VL   ++         +V++ +     G G+ 
Sbjct  88   VREAPAAGDLKGLADAWQANFEANVLSAVLVTAALKPRFADNVRVVTLGSIAAKQGSGSY  147

Query  143  SAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY-------EGLS---------RT  186
             A KAA+  W    A   G  G T N VA G  + T +       E LS         R 
Sbjct  148  GAAKAAIEAWNTDLARQLGAAG-TANVVAPGVVLDTEFFHGTLTEEWLSSRIAIAFNQRA  206

Query  187  PAPVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
              P   EIA    FL  P A H+TGQ +HV+ GA
Sbjct  207  GRP--EEIADTVRFLAAPEAAHLTGQVVHVNGGA  238


>gi|300790037|ref|YP_003770328.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
U32]
 gi|299799551|gb|ADJ49926.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
U32]
 gi|340531713|gb|AEK46918.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Amycolatopsis mediterranei 
S699]
Length=242

 Score = 70.9 bits (172),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 63/212 (30%), Positives = 95/212 (45%), Gaps = 18/212 (8%)

Query  26   GHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDA  85
            G +VT+ G R   L  AA       VV D  DP ++  A    P  +D +VN    + D 
Sbjct  28   GERVTITGRREKVLTEAAALAGARPVVFDAADPVAVEGALDELPGRVDVLVNNAGGNTDF  87

Query  86   GDPRAYS-VSDTANAWRNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAG-GAES  143
             D      ++  A A+   L + V+S  L   ++ D L  G  I+++ +     G G+  
Sbjct  88   LDGDGEEGLAGFAAAFERNLRSNVVSAALVTHALRDRLGEGARIITIGSIAAHTGAGSYG  147

Query  144  AIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY---------------EGLSRTPA  188
            A KAA+  W    A  FG RGIT N VA G   +T +                 +++ P 
Sbjct  148  AAKAAVEGWNVSVARQFGPRGITANVVAPGLIGETEFFHGQLSDQRRDRLIGNTMNKRPG  207

Query  189  PVAAEIARLALFLTTPAARHITGQTLHVSHGA  220
                ++  +  FL +PAA H+TGQ +HV+ GA
Sbjct  208  -TPDDVVAVVTFLASPAAGHVTGQVVHVNGGA  238


>gi|333372061|ref|ZP_08463997.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Desmospora sp. 8437]
 gi|332974969|gb|EGK11879.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Desmospora sp. 8437]
Length=260

 Score = 70.5 bits (171),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 71/246 (29%), Positives = 108/246 (44%), Gaps = 33/246 (13%)

Query  6    LVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDA---VVCDTTDPTSLT  62
            LVT G   LGR +A     +G +V L G   G+ E +A+E+  +    VV    D +   
Sbjct  11   LVTAGSRGLGRAVALELAREGARVALAGRDLGNAEQSAEEIASETGSEVVGWRCDVSRGE  70

Query  63   EARGLFPRHLDTIVNVPAPSWDAGDPR--AYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
            E R L  R  D    V     +AG P   A+   D  +AW+ A +  +LSVV  V++   
Sbjct  71   EVRELVDRAADRFQGVDLLVCNAGGPPGGAFDALDD-DAWQKAFETNLLSVVRLVRATLP  129

Query  121  HLRSGGSIVSV----VAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSV  176
            H++ GG I+++    V +  P     + ++A ++  +   +   G RGI +NT+  GR  
Sbjct  130  HMKDGGRILTIASSSVKQPIPGLILSNTMRAGVAGLMKTLSEELGPRGILVNTLCPGRIA  189

Query  177  QTGYEGLSRTPA------------------PVA-----AEIARLALFLTTPAARHITGQT  213
                  L R  A                  P+      AE AR A+FL + A  +ITG +
Sbjct  190  TDRLRELDRLKAEREGKPEEVIQRESLRGIPLGRYGEPAEFARTAVFLLSRANTYITGTS  249

Query  214  LHVSHG  219
            L V  G
Sbjct  250  LMVDGG  255


>gi|345011260|ref|YP_004813614.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger 
Tu 4113]
 gi|344037609|gb|AEM83334.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger 
Tu 4113]
Length=247

 Score = 69.7 bits (169),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 72/245 (30%), Positives = 104/245 (43%), Gaps = 27/245 (11%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELD-------VDAVVC  53
            M   ++V+GG T +G   AE F  +G +V ++G R   L  AA +L+       V     
Sbjct  1    MGRRIVVSGGGTGIGLAAAETFAAEGDRVVILGRRAEVLRTAADKLNAAYGPDLVTWTSA  60

Query  54   DTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVL  113
            D +DP     A           V V     +       ++   A+ ++    A VL+ VL
Sbjct  61   DLSDPEQTRRAAEFIAADGGVDVVVTNAGGNVAASNDGTLEGIADQYQRNFAANVLTAVL  120

Query  114  TVQSVGDHL-RSGGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINT  169
              +++  HL R GG IV   SV A   P  G+    KAAL  +    A   G  G+T N 
Sbjct  121  LTEALLPHLTRPGGRIVHLSSVAALRGP--GSYGGTKAALHTYTFELAKRLGPEGVTANA  178

Query  170  VACGRSVQTGYEGLSRTPAPVA--------------AEIARLALFLTTPAARHITGQTLH  215
            VA G    T + G   TP  +A               EIA    +L +P A ++TGQ LH
Sbjct  179  VAPGYVEDTEFFGDRGTPEFIAQQIGQTLTGQPGTPVEIAAAIRYLASPEAAYVTGQVLH  238

Query  216  VSHGA  220
            ++ GA
Sbjct  239  INGGA  243


>gi|298249729|ref|ZP_06973533.1| short-chain dehydrogenase/reductase SDR [Ktedonobacter racemifer 
DSM 44963]
 gi|297547733|gb|EFH81600.1| short-chain dehydrogenase/reductase SDR [Ktedonobacter racemifer 
DSM 44963]
Length=250

 Score = 69.3 bits (168),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 68/250 (28%), Positives = 109/250 (44%), Gaps = 35/250 (14%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKEL---------DVDAV  51
             A  +++TGG++ +GR MAE F  +G +V ++G  R  L   A+EL         DV   
Sbjct  4    QARRIIITGGNSGMGRAMAERFAREGAQVAIIGRDRNTLRATAEELGSQVSWYQADVSQR  63

Query  52   VCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSV  111
                +  T++ E  G     +D ++N  A  +  G      + +    W   +DA +   
Sbjct  64   EQVQSTVTAIVEQWG----QVDVLIN--AAGFVRGATTDMPLDEAEREWDAVIDANLKGS  117

Query  112  VLTVQSVGDHL-RSGGSIVSVVAENPPAGG------AESAIKAALSNWIAGQAAVFGTRG  164
             L   +VG +L R GG I+ + +     GG      A +A KA L     G A    ++ 
Sbjct  118  FLMTVAVGPYLVRPGGRIIYISSIAAFTGGSRAGSTAYAASKAGLHGLTYGFARELSSQS  177

Query  165  ITINTVACGRSVQTGYEG----------LSRTPAPVAAEIARLAL---FLTTPAARHITG  211
            IT+N VA G    TG+ G          +  TPA     +  +     +L +P A  +TG
Sbjct  178  ITVNAVAPGYIADTGFTGAWTDEKINGIIKETPAGRGGHVDDVVAAVHYLASPEASFVTG  237

Query  212  QTLHVSHGAL  221
            + L+V+ G L
Sbjct  238  EVLNVNGGWL  247


>gi|330470238|ref|YP_004407981.1| short-chain dehydrogenase/reductase SDR [Verrucosispora maris 
AB-18-032]
 gi|328813209|gb|AEB47381.1| short-chain dehydrogenase/reductase SDR [Verrucosispora maris 
AB-18-032]
Length=242

 Score = 68.6 bits (166),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 74/242 (31%), Positives = 106/242 (44%), Gaps = 29/242 (11%)

Query  6    LVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELD--------VDAVVCDTTD  57
            +V+GG T +G  +A     DG  V ++G R   L   A+ +         V AV  D TD
Sbjct  1    MVSGGGTGIGAAVARTLVADGCSVLVLGRRAEVLATTAERIGAETGRPEAVRAVSVDLTD  60

Query  58   PTSLTEA-RGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQ  116
            P  +      +  R +D +VN       A D    +++  A  WR  LD  VL+ VL   
Sbjct  61   PEQIGRVVEAVDGRPVDVLVNNAGGFHSAQDD---TLAGIAANWRATLDTNVLTAVLLTA  117

Query  117  SVGDHLRSGGS---IVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACG  173
            ++   LR  G    ++S +A     G A SA KAAL  W    AA  G   IT+N V+ G
Sbjct  118  ALRPALRRPGGRVILISSIAAQRGGGDAYSAAKAALHGWAYSLAAELGPEQITVNVVSPG  177

Query  174  RSVQTGYEGLSRTP----APVAA----------EIARLALFLTTPAARHITGQTLHVSHG  219
               +T +     TP      VAA          +IA    +L +PAA  +T Q L V+ G
Sbjct  178  YVAETEFFVGRMTPEGHAKRVAATLVGRAGTPDDIAESVRYLASPAASFVTAQILGVNGG  237

Query  220  AL  221
            ++
Sbjct  238  SV  239


>gi|167583993|ref|ZP_02376381.1| putative 3-oxacyl-ACP reductase [Burkholderia ubonensis Bu]
Length=258

 Score = 67.8 bits (164),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 77/252 (31%), Positives = 110/252 (44%), Gaps = 32/252 (12%)

Query  1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELD--------VDAVV  52
            M+  V+V+GG T +G   A  F   G +V +VG R   L  AA+++         V  +V
Sbjct  3    MSQLVVVSGGGTGIGFATARHFAQRGAQVAIVGRRADVLAHAAEQIGNAFPDAPGVAPLV  62

Query  53   CDTTDPTSLTE-ARGLFPRH--LDTIVNVPAPS-WDAGDPRAYS--VSDTANAWRNALDA  106
             D   P  +    R L  R   +D IVN           P AY+  ++  A  W +    
Sbjct  63   ADLAVPEQVEAIVRALTARFPTVDAIVNAAGGHVLRQSPPDAYADGLAGVARRWTDNFRK  122

Query  107  TVLSVVLTVQSVGDHLRS-GGSIV---SVVAENPPAGGAESAIKAALSNWIAGQAAVFGT  162
              LS VL  +++  HLR  GG IV   S+ A      G   A KAAL  + A  A   G 
Sbjct  123  NTLSAVLLTEALLPHLRQPGGRIVFLSSIAAFRGSGVGCYGASKAALHPYTADLAKALGP  182

Query  163  RGITINTVACGRSVQTGYEGLSRTPAP--------------VAAEIARLALFLTTPAARH  208
            +G+T+NTVA G    T + G + + A                  +IA    +L +P A H
Sbjct  183  KGVTVNTVAPGFVADTEFFGAALSDAQRKDKVAESLNGRAGTPDDIANTIGWLASPDALH  242

Query  209  ITGQTLHVSHGA  220
            +TGQ + V+ GA
Sbjct  243  VTGQVIQVNGGA  254



Lambda     K      H
   0.316    0.131    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 289298170616


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40