BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1865c

Length=286
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609002|ref|NP_216381.1|  short chain dehydrogenase [Mycobact...   569    2e-160
gi|340626873|ref|YP_004745325.1|  putative short-chain type dehyd...   568    3e-160
gi|167970346|ref|ZP_02552623.1|  short chain dehydrogenase [Mycob...   567    7e-160
gi|254819328|ref|ZP_05224329.1|  short chain dehydrogenase [Mycob...   468    3e-130
gi|183982749|ref|YP_001851040.1|  short-chain type dehydrogenase ...   467    1e-129
gi|240170499|ref|ZP_04749158.1|  short chain dehydrogenase [Mycob...   465    4e-129
gi|118618402|ref|YP_906734.1|  short chain dehydrogenase [Mycobac...   461    4e-128
gi|342861238|ref|ZP_08717886.1|  short chain dehydrogenase [Mycob...   461    7e-128
gi|296164859|ref|ZP_06847415.1|  short-chain dehydrogenase/reduct...   456    3e-126
gi|118464745|ref|YP_882040.1|  short chain dehydrogenase [Mycobac...   449    2e-124
gi|254775330|ref|ZP_05216846.1|  short chain dehydrogenase [Mycob...   447    8e-124
gi|41407672|ref|NP_960508.1|  short chain dehydrogenase [Mycobact...   447    1e-123
gi|111020069|ref|YP_703041.1|  short chain dehydrogenase [Rhodoco...   365    5e-99 
gi|54022896|ref|YP_117138.1|  short chain dehydrogenase [Nocardia...   331    8e-89 
gi|226309083|ref|YP_002769043.1|  oxidoreductase [Rhodococcus ery...   318    8e-85 
gi|229491565|ref|ZP_04385386.1|  short chain dehydrogenase [Rhodo...   315    6e-84 
gi|326333303|ref|ZP_08199550.1|  oxidoreductase, short-chain dehy...   311    1e-82 
gi|183983041|ref|YP_001851332.1|  short-chain dehydrogenase [Myco...   308    6e-82 
gi|311742007|ref|ZP_07715817.1|  short-chain dehydrogenase/reduct...   308    6e-82 
gi|229491088|ref|ZP_04384918.1|  short chain dehydrogenase [Rhodo...   303    1e-80 
gi|118617802|ref|YP_906134.1|  short chain dehydrogenase [Mycobac...   301    6e-80 
gi|326385243|ref|ZP_08206907.1|  short chain dehydrogenase [Gordo...   298    6e-79 
gi|333920274|ref|YP_004493855.1|  putative oxidoreductase [Amycol...   289    3e-76 
gi|311742617|ref|ZP_07716426.1|  short-chain dehydrogenase/reduct...   281    6e-74 
gi|269127923|ref|YP_003301293.1|  short-chain dehydrogenase/reduc...   250    2e-64 
gi|302529950|ref|ZP_07282292.1|  cis-2,3-dihydrobiphenyl-2,3-diol...   238    1e-60 
gi|333919894|ref|YP_004493475.1|  dehydrogenase [Amycolicicoccus ...   230    2e-58 
gi|41407814|ref|NP_960650.1|  short chain dehydrogenase [Mycobact...   226    2e-57 
gi|118463032|ref|YP_881891.1|  short chain dehydrogenase [Mycobac...   225    5e-57 
gi|300789730|ref|YP_003770021.1|  short-chain dehydrogenase/reduc...   224    1e-56 
gi|284047354|ref|YP_003397694.1|  short-chain dehydrogenase/reduc...   216    4e-54 
gi|169631412|ref|YP_001705061.1|  putative short-chain dehydrogen...   212    5e-53 
gi|333919929|ref|YP_004493510.1|  short-chain dehydrogenase/reduc...   207    1e-51 
gi|262203656|ref|YP_003274864.1|  short-chain dehydrogenase/reduc...   206    4e-51 
gi|326330073|ref|ZP_08196387.1|  oxidoreductase, short-chain dehy...   204    2e-50 
gi|304311911|ref|YP_003811509.1|  Predicted short-chain dehydroge...   202    3e-50 
gi|169630486|ref|YP_001704135.1|  short chain dehydrogenase [Myco...   201    1e-49 
gi|145220822|ref|YP_001131500.1|  short chain dehydrogenase [Myco...   201    1e-49 
gi|311742070|ref|ZP_07715880.1|  short-chain dehydrogenase/reduct...   196    3e-48 
gi|343927814|ref|ZP_08767282.1|  putative oxidoreductase [Gordoni...   196    3e-48 
gi|304310623|ref|YP_003810221.1|  Short-chain dehydrogenase [gamm...   193    3e-47 
gi|118470236|ref|YP_885177.1|  short chain dehydrogenase [Mycobac...   188    7e-46 
gi|317509446|ref|ZP_07967064.1|  short chain dehydrogenase [Segni...   187    1e-45 
gi|120401705|ref|YP_951534.1|  short chain dehydrogenase [Mycobac...   187    1e-45 
gi|108797508|ref|YP_637705.1|  short chain dehydrogenase [Mycobac...   187    1e-45 
gi|169628617|ref|YP_001702266.1|  short chain dehydrogenase [Myco...   187    2e-45 
gi|333918451|ref|YP_004492032.1|  Cis-2,3-dihydrobiphenyl-2,3-dio...   185    6e-45 
gi|317506201|ref|ZP_07964020.1|  short chain dehydrogenase [Segni...   185    8e-45 
gi|333989010|ref|YP_004521624.1|  short-chain dehydrogenase [Myco...   184    2e-44 
gi|254447794|ref|ZP_05061259.1|  3-hydroxybutyrate dehydrogenase ...   183    2e-44 


>gi|15609002|ref|NP_216381.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv]
 gi|15841334|ref|NP_336371.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551]
 gi|31793055|ref|NP_855548.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97]
 77 more sequence titles
 Length=286

 Score =  569 bits (1466),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 285/286 (99%), Positives = 286/286 (100%), Gaps = 0/286 (0%)

Query  1    VPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60
            +PGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD
Sbjct  1    MPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60

Query  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI  120
            LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI
Sbjct  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI  120

Query  121  NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180
            NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY
Sbjct  121  NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180

Query  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240
            RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS
Sbjct  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240

Query  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE
Sbjct  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286


>gi|340626873|ref|YP_004745325.1| putative short-chain type dehydrogenase [Mycobacterium canettii 
CIPT 140010059]
 gi|340005063|emb|CCC44212.1| putative short-chain type dehydrogenase [Mycobacterium canettii 
CIPT 140010059]
Length=286

 Score =  568 bits (1465),  Expect = 3e-160, Method: Compositional matrix adjust.
 Identities = 284/286 (99%), Positives = 286/286 (100%), Gaps = 0/286 (0%)

Query  1    VPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60
            +PGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD
Sbjct  1    MPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60

Query  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI  120
            LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMP+GRIVDEPDPVTRRILDI
Sbjct  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPLGRIVDEPDPVTRRILDI  120

Query  121  NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180
            NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY
Sbjct  121  NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180

Query  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240
            RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS
Sbjct  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240

Query  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE
Sbjct  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286


>gi|167970346|ref|ZP_02552623.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Ra]
Length=286

 Score =  567 bits (1461),  Expect = 7e-160, Method: Compositional matrix adjust.
 Identities = 284/286 (99%), Positives = 285/286 (99%), Gaps = 0/286 (0%)

Query  1    VPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60
            +PGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD
Sbjct  1    MPGRTSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGAD  60

Query  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI  120
            LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI
Sbjct  61   LDLDMYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDI  120

Query  121  NVYGVILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180
            NVYGVILGS LAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY
Sbjct  121  NVYGVILGSTLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEY  180

Query  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240
            RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS
Sbjct  181  RSAGVKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGS  240

Query  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE
Sbjct  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286


>gi|254819328|ref|ZP_05224329.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 
13950]
Length=282

 Score =  468 bits (1205),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 230/281 (82%), Positives = 256/281 (92%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            S+G+K+R KV    I ITGGARGIGLATA ALHNLGAKVAIGD+DE   KESGADL LD+
Sbjct  6    SLGLKVRGKV----IVITGGARGIGLATATALHNLGAKVAIGDVDEVRVKESGADLGLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTDP SF+ FLD VER+LGPIDVL+NNAGIMPVGRIVDEPD VTRRILDINVYGV
Sbjct  62   YGKLDVTDPHSFADFLDQVERRLGPIDVLINNAGIMPVGRIVDEPDAVTRRILDINVYGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            ILGSKLAAQRMVPRG GHVINVASLAGE+Y VG+ATYCASKHAVVAFTDSARLEYRSAGV
Sbjct  122  ILGSKLAAQRMVPRGTGHVINVASLAGELYIVGLATYCASKHAVVAFTDSARLEYRSAGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            KFS VLP+FVNTEL AGT G KGF+NAEPA+IADAIV L+ HPKPRVR+TKAAG+M+V+Q
Sbjct  182  KFSAVLPTFVNTELTAGTDGAKGFRNAEPAEIADAIVKLVAHPKPRVRITKAAGAMVVSQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +F PR+++EGLNR+LGG+HVFTDDVD+EKR+ YEARARGEE
Sbjct  242  KFWPRRIAEGLNRMLGGDHVFTDDVDVEKRQAYEARARGEE  282


>gi|183982749|ref|YP_001851040.1| short-chain type dehydrogenase [Mycobacterium marinum M]
 gi|183176075|gb|ACC41185.1| short-chain type dehydrogenase [Mycobacterium marinum M]
Length=285

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 228/281 (82%), Positives = 255/281 (91%), Gaps = 4/281 (1%)

Query  5    TSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLD  64
            T+IGV++RDKV    I ITGGARGIGLATA ALH LGAKVAIGD+DE   KE+GADL L+
Sbjct  5    TTIGVRVRDKV----IVITGGARGIGLATATALHKLGAKVAIGDVDEPAVKEAGADLGLE  60

Query  65   MYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYG  124
            +YGKLDVTDP+SFS FLD VERQLGP+DVLVNNAGIMPVGRIVDEPD VTRRILDINVYG
Sbjct  61   VYGKLDVTDPNSFSDFLDQVERQLGPLDVLVNNAGIMPVGRIVDEPDSVTRRILDINVYG  120

Query  125  VILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAG  184
            V++GSKLAAQRMVPRGRGHVINVASLAGEIY VG+ATYCASKHAV+AFTD+AR+EYRS G
Sbjct  121  VMVGSKLAAQRMVPRGRGHVINVASLAGEIYVVGLATYCASKHAVIAFTDAARIEYRSTG  180

Query  185  VKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVA  244
            VKFSMVLP+FVNTEL +GT G+KGFKNAEP+DIADAIV L+ +PKPRVRVTKAAG+MI +
Sbjct  181  VKFSMVLPTFVNTELASGTPGMKGFKNAEPSDIADAIVALVANPKPRVRVTKAAGAMIAS  240

Query  245  QRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGE  285
            Q+++PR +SEGLNRLLGGEHVFTDDVD  KR  YEARARGE
Sbjct  241  QKYLPRWLSEGLNRLLGGEHVFTDDVDAAKREAYEARARGE  281


>gi|240170499|ref|ZP_04749158.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478]
Length=282

 Score =  465 bits (1196),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 229/281 (82%), Positives = 255/281 (91%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            S+G+K+R KV    I ITGGARGIGLATA ALH LGA+VAIGDIDEA  KESGADL LD+
Sbjct  6    SLGIKVRGKV----IVITGGARGIGLATATALHRLGARVAIGDIDEAKVKESGADLGLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTD DSFS FLD VERQLGPIDVLVNNAGIMPVGRI+DEPD VTRRILDINV+GV
Sbjct  62   YGKLDVTDRDSFSDFLDRVERQLGPIDVLVNNAGIMPVGRIIDEPDSVTRRILDINVFGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            ILGSKLA +RM+PRG G VINVASLAGE+YAVG+ATYCASKHAVVAFTDSARLEYRSAGV
Sbjct  122  ILGSKLAVERMLPRGSGQVINVASLAGELYAVGLATYCASKHAVVAFTDSARLEYRSAGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            KFSMVLP+FVNTEL AGT G+KGFKNAEP +IADAIV L+ HPKPRVRVT+AAG+M+V+Q
Sbjct  182  KFSMVLPTFVNTELTAGTAGVKGFKNAEPENIADAIVRLVAHPKPRVRVTRAAGAMVVSQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +FMPR V+EGLNR+LGGEHVFTDDVD+ KR+ YEARARG++
Sbjct  242  KFMPRPVAEGLNRILGGEHVFTDDVDVAKRKAYEARARGQD  282


>gi|118618402|ref|YP_906734.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99]
 gi|118570512|gb|ABL05263.1| short-chain type dehydrogenase [Mycobacterium ulcerans Agy99]
Length=285

 Score =  461 bits (1187),  Expect = 4e-128, Method: Compositional matrix adjust.
 Identities = 225/281 (81%), Positives = 254/281 (91%), Gaps = 4/281 (1%)

Query  5    TSIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLD  64
            T+IGV++R+KV    I ITGGARGIGLATA ALH LGAKVAIGD+ E   KE+GADL L+
Sbjct  5    TTIGVRVRNKV----IVITGGARGIGLATATALHKLGAKVAIGDVGEPAVKEAGADLGLE  60

Query  65   MYGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYG  124
            +YGKLDVTDP+SFS FLD VERQLGP+DVLVNNAGIMPVGRIVDEPD VTRRILDINVYG
Sbjct  61   VYGKLDVTDPNSFSDFLDQVERQLGPLDVLVNNAGIMPVGRIVDEPDSVTRRILDINVYG  120

Query  125  VILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAG  184
            V++GSKLAAQRMVPRGRGHVINVASLAGEIY VG+ATYCASKHAV+AFTD+AR+EYR+ G
Sbjct  121  VMVGSKLAAQRMVPRGRGHVINVASLAGEIYVVGLATYCASKHAVIAFTDAARIEYRTTG  180

Query  185  VKFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVA  244
            VKFSMVLP+FVNTEL +GT G+KGFKNAEP+DIADAIV L+ +PKPRVRVTKAAG+MI +
Sbjct  181  VKFSMVLPTFVNTELASGTPGMKGFKNAEPSDIADAIVALVANPKPRVRVTKAAGAMIAS  240

Query  245  QRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGE  285
            Q+++PR +SEGLNRLLGGEHVFTDDVD  KR  YEARARGE
Sbjct  241  QKYLPRWLSEGLNRLLGGEHVFTDDVDAAKREAYEARARGE  281


>gi|342861238|ref|ZP_08717886.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035]
 gi|342131138|gb|EGT84419.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035]
Length=282

 Score =  461 bits (1185),  Expect = 7e-128, Method: Compositional matrix adjust.
 Identities = 225/281 (81%), Positives = 254/281 (91%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            SIG+K+R KV    I ITGGARGIGLATA ALH+LGAKVAIGD+DE   KESGADL LD+
Sbjct  6    SIGLKVRHKV----IVITGGARGIGLATATALHDLGAKVAIGDVDEVRVKESGADLGLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTDP SFS FLD VERQLGPIDVL+NNAGIMPVGRIVDEPD VTRRILDINVYGV
Sbjct  62   YGKLDVTDPHSFSDFLDEVERQLGPIDVLINNAGIMPVGRIVDEPDAVTRRILDINVYGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            I+GSKLAAQRM PRGRGHVINVASLAGE+  VG+ATYCASKHAV+ FTDSARLEY  AGV
Sbjct  122  IVGSKLAAQRMAPRGRGHVINVASLAGELNIVGLATYCASKHAVIGFTDSARLEYHDAGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            KFS+VLP+FVNTEL+AGT G+KGF+NAEPA+IADAIV L+ HPKPRVR+TKAAG+M+V+Q
Sbjct  182  KFSLVLPTFVNTELVAGTPGMKGFRNAEPAEIADAIVNLVAHPKPRVRITKAAGAMVVSQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +F PR+++EGLNR+LGG+HVFTDDVD+ KRR YEARARGE+
Sbjct  242  KFWPRRIAEGLNRMLGGDHVFTDDVDVAKRRAYEARARGED  282


>gi|296164859|ref|ZP_06847415.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295899701|gb|EFG79151.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=282

 Score =  456 bits (1172),  Expect = 3e-126, Method: Compositional matrix adjust.
 Identities = 222/281 (80%), Positives = 248/281 (89%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            S+G+K+R KV    I ITGGARGIGLATA ALHNLGAKVAIGD+DE   KESGA L LD+
Sbjct  6    SVGLKVRGKV----IVITGGARGIGLATATALHNLGAKVAIGDVDEVRVKESGAALGLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTDP SFS FLD VERQLGP+DVLVNNAGIMP+GR+VDEPD VTRR+LDINVYGV
Sbjct  62   YGKLDVTDPHSFSEFLDEVERQLGPLDVLVNNAGIMPLGRVVDEPDAVTRRVLDINVYGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            ILGSKLAAQRMVPRGRGHVINVASLAGE Y  G ATYCASKHAV+ FTD+AR+EYR AGV
Sbjct  122  ILGSKLAAQRMVPRGRGHVINVASLAGETYIAGAATYCASKHAVIGFTDTARIEYRRAGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            KFS+V+P+FVNTELIAGT G KG KNAEPADIA+AIV L+ HP+PRVRVTK AG++I +Q
Sbjct  182  KFSVVMPTFVNTELIAGTSGAKGIKNAEPADIAEAIVKLVAHPRPRVRVTKTAGAIIASQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +F+PR +SEGLNR LGGEHVFTDDVD EKR+ YE+RARGEE
Sbjct  242  KFLPRALSEGLNRALGGEHVFTDDVDAEKRKAYESRARGEE  282


>gi|118464745|ref|YP_882040.1| short chain dehydrogenase [Mycobacterium avium 104]
 gi|118166032|gb|ABK66929.1| short chain dehydrogenase [Mycobacterium avium 104]
Length=282

 Score =  449 bits (1155),  Expect = 2e-124, Method: Compositional matrix adjust.
 Identities = 221/281 (79%), Positives = 246/281 (88%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            SIG+K+RDKV    + ITGGARGIGLATA ALH LGAKVAIGDIDE   KESGA LDLD+
Sbjct  6    SIGLKVRDKV----VVITGGARGIGLATATALHKLGAKVAIGDIDEVRVKESGAALDLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTDP SFS FLD VERQLGPIDVLVNNAGIMP+GR+VDE D VTRRILDINVYGV
Sbjct  62   YGKLDVTDPHSFSDFLDEVERQLGPIDVLVNNAGIMPLGRVVDESDAVTRRILDINVYGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            ILGSKLA  RM+PRGRGHVINVASLAGE Y  G ATYCASKHAVV FTD+AR+EYR +GV
Sbjct  122  ILGSKLALARMIPRGRGHVINVASLAGETYLAGAATYCASKHAVVGFTDAARIEYRRSGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            KFS+V P+FVNTELIAGT G KG +NAEP+DIADAIV L+ HP+PRVRVT+ AG++I +Q
Sbjct  182  KFSVVKPTFVNTELIAGTSGAKGVRNAEPSDIADAIVKLVAHPRPRVRVTRTAGAIIASQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +FMPR +SEGLNRLLGGEHVFTD VD+EKR+ YEARARGE+
Sbjct  242  KFMPRALSEGLNRLLGGEHVFTDAVDVEKRQAYEARARGEQ  282


>gi|254775330|ref|ZP_05216846.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 
25291]
Length=274

 Score =  447 bits (1150),  Expect = 8e-124, Method: Compositional matrix adjust.
 Identities = 218/273 (80%), Positives = 242/273 (89%), Gaps = 0/273 (0%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTD  73
            KV+DKV+ ITGGARGIGLATA ALH LGAKVAIGDIDE   KESGA LDLD+YGKLDVTD
Sbjct  2    KVRDKVVVITGGARGIGLATATALHKLGAKVAIGDIDEVRVKESGAALDLDVYGKLDVTD  61

Query  74   PDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAA  133
            P SFS FLD VERQLGPIDVLVNNAGIMP+GR+VDE D VTRRILDINVYGVILGSKLA 
Sbjct  62   PHSFSDFLDEVERQLGPIDVLVNNAGIMPLGRVVDESDAVTRRILDINVYGVILGSKLAL  121

Query  134  QRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPS  193
             RM+PRGRGHVINVASLAGE Y  G ATYCASKHAVV FTD+AR+EYR +GVKFS+V P+
Sbjct  122  ARMIPRGRGHVINVASLAGETYLAGAATYCASKHAVVGFTDAARIEYRRSGVKFSVVKPT  181

Query  194  FVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVS  253
            FVNTELIAGT G KG +NAEP+DIADAIV L+ HP+PRVRVT+ AG++I +Q+FMPR +S
Sbjct  182  FVNTELIAGTSGAKGVRNAEPSDIADAIVKLVAHPRPRVRVTRTAGAIIASQKFMPRALS  241

Query  254  EGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            EGLNRLLGGEHVFTD VD+EKR+ YEARARGE+
Sbjct  242  EGLNRLLGGEHVFTDAVDVEKRQAYEARARGEQ  274


>gi|41407672|ref|NP_960508.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396025|gb|AAS03891.1| hypothetical protein MAP_1574c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336457511|gb|EGO36517.1| short-chain alcohol dehydrogenase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=282

 Score =  447 bits (1150),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 220/281 (79%), Positives = 245/281 (88%), Gaps = 4/281 (1%)

Query  6    SIGVKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDM  65
            SIG+K+RDKV    + ITGGARGIGLATA ALH LGAKVAIGDIDE   KESGA LDLD+
Sbjct  6    SIGLKVRDKV----VVITGGARGIGLATATALHKLGAKVAIGDIDEVRVKESGAALDLDV  61

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            YGKLDVTDP SFS FLD VERQLGPIDVLVNNAGIMP+GR+VDE D VTRRILDINVYGV
Sbjct  62   YGKLDVTDPHSFSDFLDEVERQLGPIDVLVNNAGIMPLGRVVDESDAVTRRILDINVYGV  121

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            ILGSKLA  RM+PRGRGHVINVASLAGE Y  G ATYCASKHAVV FTD+AR+EYR +GV
Sbjct  122  ILGSKLALARMIPRGRGHVINVASLAGETYLAGAATYCASKHAVVGFTDAARIEYRRSGV  181

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
             FS+V P+FVNTELIAGT G KG +NAEP+DIADAIV L+ HP+PRVRVT+ AG++I +Q
Sbjct  182  TFSVVKPTFVNTELIAGTSGAKGVRNAEPSDIADAIVKLVAHPRPRVRVTRTAGAIIASQ  241

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +FMPR +SEGLNRLLGGEHVFTD VD+EKR+ YEARARGE+
Sbjct  242  KFMPRALSEGLNRLLGGEHVFTDAVDVEKRQAYEARARGEQ  282


>gi|111020069|ref|YP_703041.1| short chain dehydrogenase [Rhodococcus jostii RHA1]
 gi|110819599|gb|ABG94883.1| dehydrogenase [Rhodococcus jostii RHA1]
Length=275

 Score =  365 bits (936),  Expect = 5e-99, Method: Compositional matrix adjust.
 Identities = 183/269 (69%), Positives = 211/269 (79%), Gaps = 0/269 (0%)

Query  15   VQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDP  74
            +  +VIAITGGARGIG ATA AL  LGAKVAIGDID+   KES  +L L  Y KLDVTD 
Sbjct  5    LHGRVIAITGGARGIGFATATALTRLGAKVAIGDIDDVKLKESATELGLVSYRKLDVTDA  64

Query  75   DSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQ  134
            +SF  FLD VE  LGPIDVLVNNAGIMP GRI DEPD VTRRILDINV GVI GSKLA +
Sbjct  65   ESFGAFLDDVEATLGPIDVLVNNAGIMPAGRIADEPDAVTRRILDINVLGVITGSKLAVR  124

Query  135  RMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSF  194
            RM+PRGRGHV+N+ASLAGEIY  G+ATYCASK+AVV FTD+AR+E+R  G++FS VLPSF
Sbjct  125  RMLPRGRGHVVNIASLAGEIYTPGLATYCASKYAVVGFTDAARVEHRGTGIEFSAVLPSF  184

Query  195  VNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSE  254
            VNTEL AGT G+ G KNAEP DIA AIV LI  PKP+VRVTK  G++  +Q+F PR++SE
Sbjct  185  VNTELTAGTKGLPGLKNAEPEDIARAIVALIECPKPKVRVTKLVGALAASQKFFPRRISE  244

Query  255  GLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
             L R L  + VF +DVD+  R+ YE RAR
Sbjct  245  ALTRALHTDRVFLEDVDITARQAYEERAR  273


>gi|54022896|ref|YP_117138.1| short chain dehydrogenase [Nocardia farcinica IFM 10152]
 gi|54014404|dbj|BAD55774.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152]
Length=281

 Score =  331 bits (848),  Expect = 8e-89, Method: Compositional matrix adjust.
 Identities = 173/273 (64%), Positives = 207/273 (76%), Gaps = 0/273 (0%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTD  73
            ++  KV+ ITGGARGIG ATA  L +LGA+VAIGD+DEA  KESGA+L LD+YG LDVTD
Sbjct  6    RIAGKVVVITGGARGIGYATARTLRDLGAQVAIGDVDEAKVKESGAELGLDVYGALDVTD  65

Query  74   PDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAA  133
            PDSF  FLD VER LGPIDVLVNNAGIMP G   DEPD V+RRILDINVYGV+LGSKLA 
Sbjct  66   PDSFEAFLDQVERTLGPIDVLVNNAGIMPTGHFADEPDRVSRRILDINVYGVVLGSKLAT  125

Query  134  QRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPS  193
            +RM+ RGRGHVIN+ASLAG +   G+ATYCASK AV+A TD+ RLEYR  G++FS V P+
Sbjct  126  RRMLERGRGHVINIASLAGVVATPGLATYCASKAAVLALTDTLRLEYRDRGIEFSAVTPT  185

Query  194  FVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVS  253
            F NTEL+AGT G KG +NAEP +IA A+  LI  P+ RV VTK AG +   Q ++P +V 
Sbjct  186  FTNTELVAGTAGAKGMRNAEPEEIAAAVAALITTPRRRVAVTKLAGRLANLQYYVPEKVL  245

Query  254  EGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            + L   LG + VF  +VD + R  YE RARGE+
Sbjct  246  DFLGDKLGMKEVFLSEVDQQARAAYERRARGED  278


>gi|226309083|ref|YP_002769043.1| oxidoreductase [Rhodococcus erythropolis PR4]
 gi|226188200|dbj|BAH36304.1| putative oxidoreductase [Rhodococcus erythropolis PR4]
Length=275

 Score =  318 bits (814),  Expect = 8e-85, Method: Compositional matrix adjust.
 Identities = 157/254 (62%), Positives = 196/254 (78%), Gaps = 0/254 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            +V+ ITGGARGIG ATA  L +LGA+VAIGDIDEA   ++  DL +  +G+LDVTDP SF
Sbjct  8    QVVVITGGARGIGYATAKRLISLGARVAIGDIDEATLAQAAKDLGIRTFGRLDVTDPASF  67

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              FLD VE +LGPIDVLVNNAGIMPVGRIVDE D VTRRI++I+V GVI G+KLA +RM+
Sbjct  68   FDFLDTVEGELGPIDVLVNNAGIMPVGRIVDEDDTVTRRIIEIDVLGVITGTKLALRRML  127

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PRGRGHVIN+ASLAGE+   G++TYC +KHAV+ FTDS R E R  GV  S VLP+  NT
Sbjct  128  PRGRGHVINIASLAGELPCPGLSTYCGAKHAVLGFTDSVRKEVRGTGVNVSSVLPTLTNT  187

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            +L +GT G+KGF+  +P +IA+AIVGLI  P+PRVR+T+ +G ++ AQ F+PR+  E L+
Sbjct  188  QLTSGTSGMKGFREVQPEEIAEAIVGLITKPRPRVRITRVSGLLVQAQGFVPRRPYEALS  247

Query  258  RLLGGEHVFTDDVD  271
            RL G E  F  DVD
Sbjct  248  RLFGVETQFLGDVD  261


>gi|229491565|ref|ZP_04385386.1| short chain dehydrogenase [Rhodococcus erythropolis SK121]
 gi|229321246|gb|EEN87046.1| short chain dehydrogenase [Rhodococcus erythropolis SK121]
Length=275

 Score =  315 bits (806),  Expect = 6e-84, Method: Compositional matrix adjust.
 Identities = 156/254 (62%), Positives = 193/254 (76%), Gaps = 0/254 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            +V+ ITGGARGIG ATA  L +LGA VAIGDIDEA    +  DL +  +G+LDVTDP SF
Sbjct  8    QVVVITGGARGIGYATAKRLISLGATVAIGDIDEATLARAAKDLGIRTFGRLDVTDPASF  67

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              FLD VE +LGPIDVLVNNAGIMPVGRIVDE D VTRRI++I+V GVI G+KLA +RM+
Sbjct  68   FDFLDTVEGELGPIDVLVNNAGIMPVGRIVDEDDSVTRRIIEIDVLGVITGTKLALRRML  127

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PRGRGHVIN+ASLAGE+   G++TYC +KHAV+ FTDS R E R  GV  S VLP+  NT
Sbjct  128  PRGRGHVINIASLAGELPCPGLSTYCGAKHAVLGFTDSVRKEVRGTGVHISSVLPTLTNT  187

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            +L +GT G+KGF+  +P +IA+A+VGLI  P+PRVR+T+ +G ++ AQ F PR+  E L+
Sbjct  188  QLTSGTSGMKGFREVQPEEIAEAVVGLITKPRPRVRITRVSGLLVQAQGFFPRRPYEALS  247

Query  258  RLLGGEHVFTDDVD  271
            RL G E  F  DVD
Sbjct  248  RLFGVETQFLGDVD  261


>gi|326333303|ref|ZP_08199550.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae 
bacterium Broad-1]
 gi|325948947|gb|EGD41040.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae 
bacterium Broad-1]
Length=277

 Score =  311 bits (796),  Expect = 1e-82, Method: Compositional matrix adjust.
 Identities = 156/266 (59%), Positives = 193/266 (73%), Gaps = 0/266 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            K IAITGGARGIG  TA  L   G +VAIGDIDEA  K++  +L + + G LDVT PDSF
Sbjct  10   KTIAITGGARGIGYQTAKELTERGHRVAIGDIDEARIKKAADELGISVVGHLDVTHPDSF  69

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              FLD VE QLGP+DVLVNNAGIMP G   +E D VTRR ++IN+ GVI G+KLA QRM+
Sbjct  70   RAFLDMVEEQLGPLDVLVNNAGIMPTGHAHEEDDAVTRRQVEINLLGVIFGTKLALQRML  129

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR  GH+IN ASLAGE+   G+ATYCA+K AV+ FT++AR EYR +G++ S V P+F NT
Sbjct  130  PRRAGHIINTASLAGELPVPGLATYCATKFAVIGFTEAARQEYRKSGIQLSTVRPTFTNT  189

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            EL+AGT G KG +NAEP +IA A   LI HP+P VRVT+ AG M+ A +F+P +V+  L 
Sbjct  190  ELVAGTAGAKGLRNAEPEEIARATAELIEHPRPFVRVTRLAGGMVAAMKFVPGRVASALG  249

Query  258  RLLGGEHVFTDDVDMEKRRTYEARAR  283
             +LG + VF DDVDM  R+TY  R R
Sbjct  250  SVLGTDSVFLDDVDMVARQTYLDRIR  275


>gi|183983041|ref|YP_001851332.1| short-chain dehydrogenase [Mycobacterium marinum M]
 gi|183176367|gb|ACC41477.1| short-chain dehydrogenase [Mycobacterium marinum M]
Length=275

 Score =  308 bits (789),  Expect = 6e-82, Method: Compositional matrix adjust.
 Identities = 152/271 (57%), Positives = 194/271 (72%), Gaps = 0/271 (0%)

Query  11   IRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLD  70
            +   V  KV+AITGGARGIGLA A ALH LG KVAIGDIDE+ AK SG  L L +   LD
Sbjct  1    MTSSVAGKVVAITGGARGIGLAIATALHGLGTKVAIGDIDESTAKSSGDRLGLPLACGLD  60

Query  71   VTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSK  130
            VT+  SF+ FLD VE +LGP+DVLVNNAG++ VG  VDEPD  T R+ D+NV+GVILG+K
Sbjct  61   VTNRQSFTAFLDTVEDKLGPLDVLVNNAGLISVGSAVDEPDDATHRLFDVNVHGVILGTK  120

Query  131  LAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMV  190
            LAAQRM+PR RGHVIN+ S+   +   G+ATYCA+KHAV+ +TD+ R+E R  GV FS++
Sbjct  121  LAAQRMLPRRRGHVINIGSVGSMLPTEGIATYCATKHAVLGYTDAVRMETRGKGVHFSVI  180

Query  191  LPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPR  250
            +P+  NTE++AG G  KGFKNAEP D+A A+VG+I  P+P V V ++ G  + AQR MP 
Sbjct  181  MPTLTNTEMVAGVGHAKGFKNAEPEDVARAVVGVIAKPEPHVAVPRSLGVTLWAQRLMPL  240

Query  251  QVSEGLNRLLGGEHVFTDDVDMEKRRTYEAR  281
             ++E L R LG   VFT D+  ++   Y  R
Sbjct  241  GLAEALGRALGSGRVFTTDLRRDQHDVYTRR  271


>gi|311742007|ref|ZP_07715817.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
 gi|311314500|gb|EFQ84407.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
Length=283

 Score =  308 bits (789),  Expect = 6e-82, Method: Compositional matrix adjust.
 Identities = 150/274 (55%), Positives = 198/274 (73%), Gaps = 0/274 (0%)

Query  9    VKIRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGK  68
            V     ++ +V+ ITGGARGIG ATA  L   GA+VAIGDIDE     +  +L L++ G+
Sbjct  7    VMTSSSLRGQVVVITGGARGIGYATARTLIERGARVAIGDIDETRLLAAADELGLEVTGR  66

Query  69   LDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILG  128
            LDVTD +SF  F   V  +LG  DVL+NNAGIMPVG  ++EP+   RR++DIN++GVI G
Sbjct  67   LDVTDGESFRAFYSMVSERLGTPDVLINNAGIMPVGPTLEEPEEAARRMVDINLHGVITG  126

Query  129  SKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFS  188
            +K+A   M+PR  GH+IN+AS+AGE +  G ATYCA+K AV+AFT++ RLE+R++GV  S
Sbjct  127  TKIALASMLPRRNGHIINIASMAGEAFVPGAATYCATKAAVIAFTEAVRLEHRTSGVSVS  186

Query  189  MVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFM  248
            +VLP+F NTEL+AGT G +GF+NAEP +IADAI GL+  P+PR  VT+  G ++ AQRFM
Sbjct  187  LVLPTFTNTELVAGTTGPRGFRNAEPEEIADAIAGLLERPRPRAYVTRVMGQVLAAQRFM  246

Query  249  PRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARA  282
            PR V+EGL R LGGE +F   VD   R+ YE RA
Sbjct  247  PRSVAEGLARRLGGEQMFLAGVDPSARQAYEQRA  280


>gi|229491088|ref|ZP_04384918.1| short chain dehydrogenase [Rhodococcus erythropolis SK121]
 gi|229322008|gb|EEN87799.1| short chain dehydrogenase [Rhodococcus erythropolis SK121]
Length=278

 Score =  303 bits (777),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 154/266 (58%), Positives = 191/266 (72%), Gaps = 0/266 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            K +AITGGARGIG  TA  L   G +VAIGDIDEA AKE+ A+L + +  +LDVTDPDSF
Sbjct  11   KTVAITGGARGIGYQTAKELIRRGHRVAIGDIDEARAKETAAELGVKVVTRLDVTDPDSF  70

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              FLD VE  LGP+DVL+NNAGIMP G   +E D VTRR ++INV GVI G+KLA QRM+
Sbjct  71   KDFLDLVEGDLGPLDVLINNAGIMPTGHTHEEDDAVTRRQVEINVLGVIFGTKLALQRML  130

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR  GH+IN ASLAGE+   G+ATYC +K AV+ FT++ARLEYR +GV+ S V P+F NT
Sbjct  131  PRRTGHIINTASLAGELAVPGLATYCGTKFAVIGFTEAARLEYRKSGVRLSTVRPTFTNT  190

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            EL+AGT G KG +NAEP +IA     LI  P+P VRVT+ AGSM+ A +F+P +++  L 
Sbjct  191  ELVAGTAGAKGLRNAEPEEIARVTGELIEKPRPFVRVTRLAGSMVAAMKFVPERLATRLG  250

Query  258  RLLGGEHVFTDDVDMEKRRTYEARAR  283
              L  + VF DDVDM  R+ Y  R R
Sbjct  251  SALDTDSVFLDDVDMGARQAYLDRIR  276


>gi|118617802|ref|YP_906134.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99]
 gi|118569912|gb|ABL04663.1| short-chain dehydrogenase [Mycobacterium ulcerans Agy99]
Length=275

 Score =  301 bits (772),  Expect = 6e-80, Method: Compositional matrix adjust.
 Identities = 148/264 (57%), Positives = 189/264 (72%), Gaps = 0/264 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            KV+AITG ARGIGLA A ALH LG KVAIGD DE+ AK SG  L L +   LDVT+  SF
Sbjct  8    KVVAITGRARGIGLAIATALHGLGTKVAIGDFDESTAKSSGDRLGLPLACGLDVTNRQSF  67

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
            + FLD VE +LGP+DVLVNNAG++ VG  VDEPD  T R+ D+NV+GVILG+KLA QRM+
Sbjct  68   TAFLDTVEDKLGPLDVLVNNAGLISVGSAVDEPDDATHRLFDVNVHGVILGTKLATQRML  127

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR RGHVIN+ S+   +   G+ATYCA+KHAV+ +TD+ R+E R  GV FS+++P+  NT
Sbjct  128  PRRRGHVINIGSVGSMLPTEGIATYCATKHAVLGYTDAVRMETRGKGVHFSVIMPTLTNT  187

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            E++AG G  KGFKNAEP D+A A+VG+I  P+P V V ++ G  + AQR MP  ++E L 
Sbjct  188  EMVAGVGHAKGFKNAEPEDVARAVVGVIAKPEPHVAVPRSLGVTLWAQRLMPLGLAEALG  247

Query  258  RLLGGEHVFTDDVDMEKRRTYEAR  281
            R LG   VFT D+  ++   Y  R
Sbjct  248  RALGSGRVFTTDLRRDQHDVYTRR  271


>gi|326385243|ref|ZP_08206907.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395]
 gi|326196027|gb|EGD53237.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395]
Length=278

 Score =  298 bits (763),  Expect = 6e-79, Method: Compositional matrix adjust.
 Identities = 151/266 (57%), Positives = 190/266 (72%), Gaps = 0/266 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            K +AITGGARGIG  TA  L   G +VAIGD+DEA AKE+  +L + +  +LDVTDPDSF
Sbjct  11   KTVAITGGARGIGYQTAKELIRRGHRVAIGDVDEARAKEAAVELGVKVVTRLDVTDPDSF  70

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              FLD VE  LGP+DVL+NNAGIMP G   +E D VTRR ++INV GVI G+KLA QRM+
Sbjct  71   REFLDLVEGGLGPLDVLINNAGIMPTGHAHEEADAVTRRQVEINVLGVIFGTKLALQRML  130

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR  GH+IN ASLAGE+   G+ATYC +K AV+ FT++AR EYR +GV+ S V P+F NT
Sbjct  131  PRRAGHIINTASLAGELAVPGLATYCGTKFAVIGFTEAARQEYRKSGVQLSTVRPTFTNT  190

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            EL+AGT G KG +NAEP +IA A   LI +P+  VRVT+ AG M+ A +F+P +++  L 
Sbjct  191  ELVAGTAGAKGLRNAEPEEIARATADLIENPRSFVRVTRLAGGMVAAMKFVPGRLATWLG  250

Query  258  RLLGGEHVFTDDVDMEKRRTYEARAR  283
              LG + VF DDVDM  R+ Y  R R
Sbjct  251  SALGTDSVFLDDVDMRIRQAYLDRIR  276


>gi|333920274|ref|YP_004493855.1| putative oxidoreductase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333482495|gb|AEF41055.1| Putative oxidoreductase [Amycolicicoccus subflavus DQS3-9A1]
Length=275

 Score =  289 bits (740),  Expect = 3e-76, Method: Compositional matrix adjust.
 Identities = 144/266 (55%), Positives = 187/266 (71%), Gaps = 0/266 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            +V+ ITGGARGIG ATA  L + GAKVAIGDIDEA  K +  DL    + +LDVTD DSF
Sbjct  8    RVVVITGGARGIGYATAKHLISQGAKVAIGDIDEAQLKTAADDLGTVAHKRLDVTDADSF  67

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
              F D VE Q GP+DVL+NNAGIMPVG ++DE + + RR+ +INV+GVI G+K+A + M+
Sbjct  68   KEFFDFVETQAGPVDVLINNAGIMPVGLVIDEDETIVRRMFEINVFGVITGTKIALRSML  127

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PRG G +IN+ASLAGE+   G+A+YC +KHAV+ F+DS R E RS+GV  S +LP+  NT
Sbjct  128  PRGAGQIINIASLAGEMTFPGLASYCGTKHAVLGFSDSVRKEVRSSGVTVSCILPTITNT  187

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            +L +G  GI+G + AEP +IA AI  +I  P PR RVT  AGS++ AQ F P  + E + 
Sbjct  188  QLASGAKGIRGIRTAEPEEIAAAIARVIEKPVPRTRVTGLAGSLVRAQHFFPHGLYERIG  247

Query  258  RLLGGEHVFTDDVDMEKRRTYEARAR  283
            R LG +  F  D+D+  RR YE RAR
Sbjct  248  RFLGADTQFVTDLDVTARRDYEDRAR  273


>gi|311742617|ref|ZP_07716426.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
 gi|311314245|gb|EFQ84153.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
Length=267

 Score =  281 bits (720),  Expect = 6e-74, Method: Compositional matrix adjust.
 Identities = 140/263 (54%), Positives = 182/263 (70%), Gaps = 0/263 (0%)

Query  19   VIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSFS  78
            ++AITGGARGIG  TA  L   G +VAIGDIDE   K +  +L LD+  +LDVTDP S  
Sbjct  1    MVAITGGARGIGYHTAEELIRRGHRVAIGDIDERQLKVAAEELGLDVAVRLDVTDPASIE  60

Query  79   GFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMVP  138
             FLD  E  LG +DV +NNAG+MP G + +E D VTRR ++INV GVI G+K+A QRM+P
Sbjct  61   SFLDVTEEALGSVDVFINNAGVMPTGHVHEEADEVTRRQVEINVLGVIFGTKIALQRMLP  120

Query  139  RGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNTE  198
            R  GH+IN ASLAGE+   G+ATYC +K AV+ FT++AR EYR +G+  S V P+F NTE
Sbjct  121  RRHGHIINTASLAGELPVPGLATYCGTKFAVIGFTEAARQEYRRSGITLSTVRPTFTNTE  180

Query  199  LIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLNR  258
            L++GT G KG +NAEP +IA A   LI  P+P VRVT+ AG+M+ A +F+P +V+  L  
Sbjct  181  LVSGTSGAKGMRNAEPQEIARATADLIERPRPFVRVTRVAGTMVAAMKFVPDRVATQLGA  240

Query  259  LLGGEHVFTDDVDMEKRRTYEAR  281
            +LG + VF D VD   R+ Y  R
Sbjct  241  MLGTDTVFLDRVDAAARQAYVER  263


>gi|269127923|ref|YP_003301293.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata 
DSM 43183]
 gi|268312881|gb|ACY99255.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata 
DSM 43183]
Length=267

 Score =  250 bits (639),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 139/266 (53%), Positives = 179/266 (68%), Gaps = 2/266 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            KVIAITGGARGIG ATA  L   GAKVAIGDIDE   KE+G  LD+    KLDVTD DSF
Sbjct  3    KVIAITGGARGIGYATARTLVAKGAKVAIGDIDETAVKEAGERLDIPAL-KLDVTDRDSF  61

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
            + FL+AVE +LG +DVLVNNAGIMP+G +  E D   RR LD+NV+GV+LG+KLA +RM+
Sbjct  62   TAFLEAVEDRLGRLDVLVNNAGIMPIGPVTGESDADARRCLDVNVHGVMLGTKLALERML  121

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR  GH+IN+AS+AG +   G+A Y ASK AVVAFT++ RLE R  G+K   VLPSF +T
Sbjct  122  PRADGHIINIASVAGVLPTPGLALYNASKAAVVAFTEATRLEVRDRGIKVGAVLPSFTDT  181

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            ELIAGT   +G +N  P +IA A+  +I  P P++ V +   + +     +P  V   + 
Sbjct  182  ELIAGTRSPRGQRNCRPEEIAAAVARMIAKPVPQLVVPRRLTAQLRLMGLIPDPVKRAVA  241

Query  258  RLLGGEHVFTDDVDMEKRRTYEARAR  283
            R  G + +F  D D   R+ Y++R R
Sbjct  242  RYYGLDTLFL-DFDRNARKGYDSRIR  266


>gi|302529950|ref|ZP_07282292.1| cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [Streptomyces 
sp. AA4]
 gi|302438845|gb|EFL10661.1| cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [Streptomyces 
sp. AA4]
Length=287

 Score =  238 bits (606),  Expect = 1e-60, Method: Compositional matrix adjust.
 Identities = 127/272 (47%), Positives = 175/272 (65%), Gaps = 1/272 (0%)

Query  12   RDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGK-LD  70
            R  +  KV+ +TGGA+GIG ATAAALH  G+++ +GD+D   A+++  +L  D+    LD
Sbjct  3    RQSLSGKVVVVTGGAQGIGAATAAALHRRGSRLVLGDLDRVRAEKTAGELGPDVVASPLD  62

Query  71   VTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSK  130
            VTD  +F+ FLD VER +GPIDVL+NNAGIMP+  + +E D  TRR+L+INV+ V+ G++
Sbjct  63   VTDTAAFTAFLDDVERTVGPIDVLINNAGIMPLSPLDEEDDAATRRLLEINVHAVVHGTR  122

Query  131  LAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMV  190
             A +RM PRGRGH++NVAS+AG+    G ATYCA+KHAVV  +++ RLE R  GV+ S V
Sbjct  123  EAVKRMKPRGRGHIVNVASMAGKSGFAGAATYCATKHAVVGLSEAVRLELRGTGVEVSCV  182

Query  191  LPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPR  250
            +P+ V TEL +G G  +  K+  P D+A AIV  +  PK  V V K+        R  PR
Sbjct  183  MPAVVRTELASGLGEARFIKSVGPDDVAAAIVDALERPKFDVFVPKSLDLTGRITRLFPR  242

Query  251  QVSEGLNRLLGGEHVFTDDVDMEKRRTYEARA  282
               E L R LGG+ +        +R  YE RA
Sbjct  243  AFGEWLVRALGGDQLLASAAHSPERAEYEDRA  274


>gi|333919894|ref|YP_004493475.1| dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333482115|gb|AEF40675.1| Dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
Length=287

 Score =  230 bits (586),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 133/283 (47%), Positives = 172/283 (61%), Gaps = 13/283 (4%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTD  73
             +  + IAITG ARGIG ATA AL   GAKVAI DIDEA  K +  +L +  Y +LDVTD
Sbjct  3    SLHGQTIAITGAARGIGFATARALLLSGAKVAISDIDEAELKRAATELGVTCYARLDVTD  62

Query  74   PDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAA  133
             D+F+ FLD  E +LGPI  +VNNAGIMP G +++E   + RR+L+IN  GVI G+K A 
Sbjct  63   ADAFAAFLDYAESELGPITGIVNNAGIMPTGGLLEEQASLARRVLEINTLGVINGTKAAL  122

Query  134  QRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPS  193
            QRMVPR RGHV+N+AS  GE    G+ATY ASK A + FTD+ARLE+RS+G+KFS VLP 
Sbjct  123  QRMVPRRRGHVVNMASTMGEAPVPGLATYNASKAAAIIFTDAARLEFRSSGIKFSTVLPG  182

Query  194  FVNTELIAGTGG-----------IKGFKNAEPADIADAIVGLIVHPKP--RVRVTKAAGS  240
             VNT L  G              I   K+ EP ++A A+V  +   K   R+ V ++ G 
Sbjct  183  GVNTGLADGVDASISVPLPFGRSIPIVKHVEPEEVARAVVRALASGKSHRRIHVPRSFGV  242

Query  241  MIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
            ++ +   +P  ++E L R LG         D  KR  Y AR R
Sbjct  243  LLRSGGLLPICMNEALQRSLGAHKKILQSSDPAKRARYLARVR  285


>gi|41407814|ref|NP_960650.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396168|gb|AAS04033.1| hypothetical protein MAP_1716 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336457481|gb|EGO36490.1| short-chain alcohol dehydrogenase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=279

 Score =  226 bits (577),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 125/241 (52%), Positives = 161/241 (67%), Gaps = 6/241 (2%)

Query  15   VQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADL--DLDMYG-KLDV  71
            + DKV+AITGGARGIGLATA A    GAKVA+GD+D  +A++   +L  D  + G  LDV
Sbjct  3    LTDKVVAITGGARGIGLATAKAFLAAGAKVALGDLDTELAEKQAVELGGDPAVVGLSLDV  62

Query  72   TDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL  131
            +DP SF  FLD VE +LG +DVLV+NAGIMP G  VDEP  ++RR++D+NVYGV+ GS+L
Sbjct  63   SDPASFVAFLDDVEARLGRLDVLVSNAGIMPTGPFVDEPPTMSRRMIDVNVYGVLNGSRL  122

Query  132  AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVL  191
            AA R VPRG GH++N+ASLAG     G+ATYC +KH VV FT+S   E R   V  S+VL
Sbjct  123  AAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELRPHRVGVSLVL  182

Query  192  PSFVNTELIAGT---GGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFM  248
            P  +NTEL AGT   G  +    AEP D+A  IV  +   KPR  V    G+++ +   +
Sbjct  183  PGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVSLL  242

Query  249  P  249
            P
Sbjct  243  P  243


>gi|118463032|ref|YP_881891.1| short chain dehydrogenase [Mycobacterium avium 104]
 gi|254775183|ref|ZP_05216699.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 
25291]
 gi|118164319|gb|ABK65216.1| short chain dehydrogenase [Mycobacterium avium 104]
Length=279

 Score =  225 bits (574),  Expect = 5e-57, Method: Compositional matrix adjust.
 Identities = 125/241 (52%), Positives = 162/241 (68%), Gaps = 6/241 (2%)

Query  15   VQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADL--DLDMYG-KLDV  71
            + DKV+AITGGARGIGLATA A+   GAKVA+GD+D  +A++   +L  D  + G  LDV
Sbjct  3    LTDKVVAITGGARGIGLATAKAVLAEGAKVALGDLDTELAEKQAVELGGDPAVVGLPLDV  62

Query  72   TDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL  131
            +DP SF+ FLD VE +LG +DVLVNNAGIMP G  VDE   ++RR++D+NVYGV+ GS+L
Sbjct  63   SDPASFAAFLDDVEARLGRLDVLVNNAGIMPTGPFVDESPTMSRRMIDVNVYGVLNGSRL  122

Query  132  AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVL  191
            AA R VPRG GH++N+ASLAG     G+ATYC +KH VV FT+S   E R   V  S+VL
Sbjct  123  AAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELRPHRVGVSLVL  182

Query  192  PSFVNTELIAGT---GGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFM  248
            P  +NTEL AGT   G  +    AEP D+A  IV  +   KPR  V    G+++ +   +
Sbjct  183  PGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVSKDKPRKTVPATLGALLKSVSLL  242

Query  249  P  249
            P
Sbjct  243  P  243


>gi|300789730|ref|YP_003770021.1| short-chain dehydrogenase/reductase [Amycolatopsis mediterranei 
U32]
 gi|299799244|gb|ADJ49619.1| short-chain dehydrogenase/reductase [Amycolatopsis mediterranei 
U32]
 gi|340531398|gb|AEK46603.1| short-chain dehydrogenase/reductase [Amycolatopsis mediterranei 
S699]
Length=281

 Score =  224 bits (571),  Expect = 1e-56, Method: Compositional matrix adjust.
 Identities = 121/249 (49%), Positives = 161/249 (65%), Gaps = 1/249 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSF  77
            KV+ ITGG +GIG ATA+AL  LGAKV IGD+D+  A+++  +L  D    LDVTD   F
Sbjct  6    KVVVITGGGQGIGAATASALSRLGAKVVIGDLDQVRAEKTAGELGADAL-PLDVTDIRGF  64

Query  78   SGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMV  137
            + FLD VER+ G IDVL+NNAGIMP+G +  E D  TRR L+IN++ VI G++ A +RM 
Sbjct  65   TAFLDEVERRHGRIDVLINNAGIMPLGDLDTESDATTRRQLEINLHAVIHGTREAVKRMR  124

Query  138  PRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNT  197
            PR  GH++NVAS AG+    G ATYCA+KHAVV  +++  LE   +GV  S V+P  V T
Sbjct  125  PRRSGHIVNVASFAGKAGFPGAATYCATKHAVVGLSEAVHLELHGSGVHVSCVMPGIVRT  184

Query  198  ELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLN  257
            EL +G G  K FK+  P D+ADAIV  +  P+  V V ++ G M    R +PR+  E L 
Sbjct  185  ELASGLGEAKMFKSVRPEDVADAIVSALRKPRFDVFVPRSLGIMGKLTRLLPRRTGEALA  244

Query  258  RLLGGEHVF  266
            R L  + + 
Sbjct  245  RTLKADRLL  253


>gi|284047354|ref|YP_003397694.1| short-chain dehydrogenase/reductase SDR [Conexibacter woesei 
DSM 14684]
 gi|283951575|gb|ADB54319.1| short-chain dehydrogenase/reductase SDR [Conexibacter woesei 
DSM 14684]
Length=295

 Score =  216 bits (549),  Expect = 4e-54, Method: Compositional matrix adjust.
 Identities = 122/244 (50%), Positives = 164/244 (68%), Gaps = 1/244 (0%)

Query  18   KVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KLDVTDPDS  76
            KV+AITGGARGIG ATAAAL   GA+VAIGD+D A+ + +  +L  D+   +LDVTD  S
Sbjct  11   KVVAITGGARGIGRATAAALVAKGARVAIGDLDLAVTERTAQELGGDVVALRLDVTDRAS  70

Query  77   FSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRM  136
            F+ FL+  E++LGP+DVLVNNAGIM +G   +E D    R +DIN++GVI GSKLA  R 
Sbjct  71   FAQFLEQTEQRLGPLDVLVNNAGIMHLGVFAEESDGAATRQIDINLHGVITGSKLALARF  130

Query  137  VPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVN  196
            +PR  GH++NVAS AG+    G ATY A+KHAVV  TD+ R E R +GV+ S+V+P  VN
Sbjct  131  LPRRTGHLVNVASTAGKTGIPGGATYSATKHAVVGLTDAIRAELRGSGVETSVVMPVPVN  190

Query  197  TELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGL  256
            TEL AG    +G +  EP D+A+ IV  +  P+  V V ++ G +      +PR V+E +
Sbjct  191  TELAAGLQQGRGIEVVEPEDVANEIVAALEFPRHDVFVPRSVGPLTRFALLLPRGVAERI  250

Query  257  NRLL  260
             RL+
Sbjct  251  GRLM  254


>gi|169631412|ref|YP_001705061.1| putative short-chain dehydrogenase/reductase [Mycobacterium abscessus 
ATCC 19977]
 gi|169243379|emb|CAM64407.1| Putative short-chain dehydrogenase/reductase [Mycobacterium abscessus]
Length=283

 Score =  212 bits (539),  Expect = 5e-53, Method: Compositional matrix adjust.
 Identities = 122/270 (46%), Positives = 161/270 (60%), Gaps = 1/270 (0%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KLDVT  72
            ++  KV+A+TGGARGIG A A A    GAKVAIGDID+ + + + A++     G  LDVT
Sbjct  6    QLAGKVVAVTGGARGIGRAIATAFAAEGAKVAIGDIDKKLCENTAAEIGNSAIGLPLDVT  65

Query  73   DPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLA  132
            D  SF  F D +   +GP+DV+VNNAGIMP+    DE     +R LDINV GV+ GS+LA
Sbjct  66   DHGSFEAFFDTIAATVGPVDVIVNNAGIMPITPFDDESLESIQRQLDINVRGVMWGSQLA  125

Query  133  AQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLP  192
             +RM PRG G ++N+AS AG+    G+ATYCA+KHAVV  ++S  LEY  AG+    V+P
Sbjct  126  IKRMKPRGGGVIVNIASAAGKAGFPGLATYCATKHAVVGLSESLSLEYEPAGISVVCVMP  185

Query  193  SFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQV  252
              VNTELI+G       K  EP DIA+A+V  +      V V K  G M      +PR  
Sbjct  186  GMVNTELISGLDTHWLLKTVEPEDIANAVVKAVRRGVFPVFVPKMFGGMYRTMSVLPRST  245

Query  253  SEGLNRLLGGEHVFTDDVDMEKRRTYEARA  282
             + L R LG +    +    + R+ YE RA
Sbjct  246  GKFLTRKLGIQDFMLNAHGSDARKAYEDRA  275


>gi|333919929|ref|YP_004493510.1| short-chain dehydrogenase/reductase family oxidoreductase [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333482150|gb|AEF40710.1| Short-chain dehydrogenase/reductase family oxidoreductase [Amycolicicoccus 
subflavus DQS3-9A1]
Length=274

 Score =  207 bits (528),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 120/269 (45%), Positives = 157/269 (59%), Gaps = 3/269 (1%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KLDVT  72
             +Q + I ITG  RGIGLATA  LH  GA V IGD+DE  A  +   +  +  G  +DV+
Sbjct  5    SLQGRRIVITGAGRGIGLATAKELHTRGATVIIGDVDERSALAAAKSIGSNAEGYAVDVS  64

Query  73   DPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLA  132
              DSF+ F        G IDVL+NNAGIMP+GR +D+     RR + INV G I G  L 
Sbjct  65   GYDSFAAFHQKATAN-GIIDVLINNAGIMPIGRFLDQSADTHRRAVQINVLGAINGMHLT  123

Query  133  AQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLP  192
               MV RG GH+INVAS AG+    G  TYC +K AV+A T++AR+EY+ +G+ F+ V+P
Sbjct  124  LPAMVARGSGHIINVASTAGKTPVPGGLTYCGTKSAVIAITETARVEYKGSGIDFTCVMP  183

Query  193  SFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQV  252
            SF NTELIAGT   K     EP D+A AI   I  PKP V V +  G ++  Q  + R++
Sbjct  184  SFTNTELIAGTTATKLIPVVEPEDVARAIADAIERPKPDVFVPRIVGPLLWPQPLLGRRI  243

Query  253  SEGLNRLLGGEHVFTDDVDMEKRRTYEAR  281
             +  N  LG +  F  D D + R  Y+ R
Sbjct  244  RDLFNHSLGADRSFL-DFDPKARSGYDKR  271


>gi|262203656|ref|YP_003274864.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis 
DSM 43247]
 gi|262087003|gb|ACY22971.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis 
DSM 43247]
Length=290

 Score =  206 bits (524),  Expect = 4e-51, Method: Compositional matrix adjust.
 Identities = 126/278 (46%), Positives = 167/278 (61%), Gaps = 9/278 (3%)

Query  11   IRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLD  70
            +R  + DKV+ ITGGARGIG  TA  L   GAKVAIGDID     ++ ADL ++   ++D
Sbjct  16   LRAAIADKVVVITGGARGIGFETATQLFQAGAKVAIGDIDGDAVGKAAADLGIEGI-EVD  74

Query  71   VTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSK  130
            VT   SF  FLD VE +LGPIDVLVNNAGIMPVG  +   D + RR  DI+V GVILGS+
Sbjct  75   VTSRASFKAFLDEVESRLGPIDVLVNNAGIMPVGPFLSYDDTIIRRTFDIDVIGVILGSQ  134

Query  131  LAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMV  190
            L A+RMV RG GH++N+AS AG I   G+  Y  +K AV+ F+++   E    GVK S +
Sbjct  135  LIAERMVARGGGHIVNIASTAGRIPTPGLTIYNGAKAAVIEFSEALGAELAPEGVKVSSI  194

Query  191  LPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRV---RVTKAAGSMIVAQRF  247
            LP+F  T LI+G       +   P ++A+ +V  I  PK RV   R  K A S  +  + 
Sbjct  195  LPTFTRTALISGLKTNAFVQTVGPEEVAEIVVATIARPKVRVYAPRSMKWAESGALFPQA  254

Query  248  MPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGE  285
            M R +S  L +L   + +F +  D + R  Y +R RGE
Sbjct  255  MKR-MSRKLTKL---DSIFLNP-DQQVRAAYTSRIRGE  287


>gi|326330073|ref|ZP_08196387.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae 
bacterium Broad-1]
 gi|325952281|gb|EGD44307.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae 
bacterium Broad-1]
Length=276

 Score =  204 bits (518),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 119/271 (44%), Positives = 159/271 (59%), Gaps = 3/271 (1%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDID-EAMAKESGADLDLDMYGKLDVT  72
            +++   + +TGGARGIG AT   L   GAKVA+GD+D + +A   G      M  +LDVT
Sbjct  4    QIEGSAVIVTGGARGIGRATVERLARAGAKVAVGDLDPDLLADVVGEFGPRVMAARLDVT  63

Query  73   DPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLA  132
            DP S+  FLD V  +LGP DVLVNNAGIMP+G ++ E D +TR I D+NV+G I G K  
Sbjct  64   DPASWRSFLDTVA-ELGPWDVLVNNAGIMPLGSVLKEEDALTRAIFDVNVHGPINGIKAV  122

Query  133  AQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLP  192
            A  MV RG+GH++NVAS  G +     ATY ASK AVV F+++ RLE   AGV  S++LP
Sbjct  123  APAMVDRGQGHIVNVASAVGRVPVPDAATYSASKFAVVGFSEALRLELAPAGVDVSLILP  182

Query  193  SFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQV  252
            + V TEL  G    KG K     D+A+AI  +I  P+P V V     ++    + MPR+ 
Sbjct  183  TVVQTELADGVPPAKGMKPVTAEDVAEAIESVIREPRPEVWVPNWTQTLTKITQAMPRRF  242

Query  253  SEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
             + ++R      +    VD   R  YE R R
Sbjct  243  QDFVDRTTNASQLLA-GVDPAARAAYEERVR  272


>gi|304311911|ref|YP_003811509.1| Predicted short-chain dehydrogenase [gamma proteobacterium HdN1]
 gi|301797644|emb|CBL45865.1| Predicted short-chain dehydrogenase [gamma proteobacterium HdN1]
Length=284

 Score =  202 bits (515),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 113/279 (41%), Positives = 168/279 (61%), Gaps = 6/279 (2%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KLDV  71
            + +Q + +AITGGA+GIG +   AL   GAKVA+GDI E   +++ A+L     G +LDV
Sbjct  4    NTLQGRRVAITGGAQGIGKSIGQALVAAGAKVALGDIQEDAVQQTAAELQAGTKGYRLDV  63

Query  72   TDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL  131
            TD D F  FL      LG +DVL+NNAGIMP+G  + E   VTRR ++I++ GV+ G++L
Sbjct  64   TDADEFDAFLKQATEDLGGLDVLINNAGIMPIGPFLQESPSVTRRTIEIDLLGVLTGTRL  123

Query  132  AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVL  191
            A +     G GHVIN+AS+ G + +   ATYCA+K+AVV F+++ R E+R +GVK S + 
Sbjct  124  AGEYFARTGSGHVINIASVMGTLASPNAATYCAAKYAVVGFSEALRQEWRGSGVKISAIC  183

Query  192  PSFVNTELIAGTGG---IKGFKNAEPADIADAIVGLIVHPKPR-VRVTKAAGSMIVAQRF  247
            P FV TELI+G      ++ F   +P D+A  ++  +     R V + K  G +    +F
Sbjct  184  PGFVRTELISGMAAPRLLERFLVVDPEDVATTVITELAKGASRTVFIPKLVGLVSSGTQF  243

Query  248  MPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
            +P  + +   RL GG  V T  +D ++R  Y+AR  G +
Sbjct  244  LPTAIVDTAFRLSGGNKV-TSALDHKERAAYQARIEGRK  281


>gi|169630486|ref|YP_001704135.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977]
 gi|169242453|emb|CAM63481.1| Putative short chain dehydrogenase/reductase [Mycobacterium abscessus]
Length=284

 Score =  201 bits (511),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 128/277 (47%), Positives = 164/277 (60%), Gaps = 13/277 (4%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDID-EAMA------KESGADLDLDM  65
            DK+  K IAITG ARGIG ATA AL   GA+V IGD D EA+       KE G   ++D 
Sbjct  2    DKITGKNIAITGAARGIGYATATALLRRGARVVIGDRDVEALGSAVEGLKEEG---NVDA  58

Query  66   YGKLDVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGV  125
            +  LDVTDP SF  FL+A     GPIDVLVNNAG+MP+G  +   D   R +L++N+YGV
Sbjct  59   H-PLDVTDPASFKRFLEAASAG-GPIDVLVNNAGVMPIGPFLSTSDRAIRSMLEVNLYGV  116

Query  126  ILGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGV  185
            I G +LA   MV R RG V+N+AS+AG +   G+A Y ASK  VV  + +   E+   GV
Sbjct  117  INGCQLALPEMVARRRGQVVNIASVAGLMAVPGMAVYNASKFGVVGLSRALSDEFAPQGV  176

Query  186  KFSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQ  245
            + S VLP+F NTELIAGT      K  EP DIA A+V +I  P+ +V V K  G++    
Sbjct  177  QVSAVLPTFTNTELIAGTDSTGAQKPVEPEDIAAAVVRIIEKPRVQVTVPKPLGAVTTIV  236

Query  246  RFMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARA  282
              +P  V   +++  G + VF  D D   R  YE RA
Sbjct  237  NSLPTGVRRFMSKKTGTDRVFL-DFDTSARTAYENRA  272


>gi|145220822|ref|YP_001131500.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK]
 gi|315442225|ref|YP_004075104.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1]
 gi|145213308|gb|ABP42712.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum 
PYR-GCK]
 gi|315260528|gb|ADT97269.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1]
Length=286

 Score =  201 bits (510),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 127/276 (47%), Positives = 161/276 (59%), Gaps = 7/276 (2%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLD----LDMYGK  68
            D ++ K IAITG ARGIG ATA AL   GA+V IGD D A+ + S A L     +  Y  
Sbjct  2    DNIRGKTIAITGAARGIGYATAEALLAHGARVVIGDRDVALQESSVAKLTNLGPVSGY-P  60

Query  69   LDVTDPDSFSGFLDAVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVIL  127
            LDVTD +SF+ FLD      G  IDVL+NNAG+MPVG  +DE +   R  L++NVYGV+ 
Sbjct  61   LDVTDQESFATFLDKARTDGGGHIDVLINNAGVMPVGPFLDETEQSIRSSLEVNVYGVLT  120

Query  128  GSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKF  187
            G +LA   MV R  GH+IN+ASL+G I   G   Y  +K+AVV  T +   E    GV  
Sbjct  121  GCRLALPDMVKRRSGHIINIASLSGVIPLPGQVVYVGAKYAVVGLTTALADEMAPHGVNV  180

Query  188  SMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRF  247
            S+++P F NTELIAGT      K  EP DIA AIV  +  PK  V V         A + 
Sbjct  181  SVIMPPFTNTELIAGTKSGGAIKPVEPEDIAAAIVKTLNKPKTHVSVPPPLRFTAQAAQM  240

Query  248  MPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
            +P +    +N+ LG + VF  DVD +KR+ YE RAR
Sbjct  241  LPPKGRRAMNKALGLDTVFL-DVDTDKRKGYEERAR  275


>gi|311742070|ref|ZP_07715880.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
 gi|311314563|gb|EFQ84470.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium 
marinum DSM 15272]
Length=273

 Score =  196 bits (498),  Expect = 3e-48, Method: Compositional matrix adjust.
 Identities = 111/249 (45%), Positives = 153/249 (62%), Gaps = 2/249 (0%)

Query  20   IAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMY-GKLDVTDPDSFS  78
            + +TGGARGIG ATA  L   GA+VAIGD+D  +A    A++   +    LDVTD +S+ 
Sbjct  9    VIVTGGARGIGRATAERLSAGGARVAIGDLDAELAASVAAEIGRGVVSAHLDVTDAESWR  68

Query  79   GFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMVP  138
             FL A     GP DVLVNNAGIMP+G ++ EPD VTR I+D+N++GVI G+K  A  M+ 
Sbjct  69   TFL-AATSAAGPFDVLVNNAGIMPLGSLLKEPDDVTRTIVDVNLHGVIHGTKAVAPGMID  127

Query  139  RGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNTE  198
            RGRGHV+NVAS  G +     ATY ASK AVV F+++ R E    GV  S+VLP+ V TE
Sbjct  128  RGRGHVVNVASAVGRVAMADGATYSASKFAVVGFSEAMRAELAPQGVDVSVVLPTVVQTE  187

Query  199  LIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEGLNR  258
            L AG    +G K     D+A  I  +I+ PK  V V + + +++     +PR+  E ++R
Sbjct  188  LSAGVPAARGVKPVTADDVAKVIEEVILKPKAEVWVPRWSQAIVKTTNLLPRRAQEAISR  247

Query  259  LLGGEHVFT  267
             +  + V +
Sbjct  248  AMKADSVLS  256


>gi|343927814|ref|ZP_08767282.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433]
 gi|343762455|dbj|GAA14208.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433]
Length=299

 Score =  196 bits (498),  Expect = 3e-48, Method: Compositional matrix adjust.
 Identities = 116/278 (42%), Positives = 162/278 (59%), Gaps = 7/278 (2%)

Query  11   IRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLD  70
            IR  ++DKV+ +TGGARGIG  TA  L   GAKVAIGD+D     ++ ADL ++   ++D
Sbjct  16   IRTALKDKVVVVTGGARGIGFETATQLFQAGAKVAIGDVDGEAVGKAAADLGIEGV-EVD  74

Query  71   VTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSK  130
            VT  +SF  FL  VE +LGPIDVLVNNAGIMPVG  +   D + RR  DI+V GVI+G +
Sbjct  75   VTKRESFDAFLSEVESRLGPIDVLVNNAGIMPVGPFLSYDDTIIRRTYDIDVLGVIIGCQ  134

Query  131  LAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMV  190
             AA+RM PR  GH++N+AS AG I   G+  Y  +K AV+ F+++   E    GV  S V
Sbjct  135  EAARRMAPRRTGHIVNIASTAGRIPTPGLTIYNGAKAAVIEFSEALGAELEPEGVTVSAV  194

Query  191  LPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMP-  249
            LP+F  T LI+G    +  +   P ++A  +V  I  P  RV   ++      +  F P 
Sbjct  195  LPTFTRTALISGLQTNRFIQTVAPEEVAAIVVETIARPVTRVYAPRSMRWADSSPLFPPA  254

Query  250  -RQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARGEE  286
             ++ +  L +L   + +F    D E R  Y +R RGE+
Sbjct  255  MKRFTRKLTKL---DSIFLRP-DQEARAAYASRIRGEK  288


>gi|304310623|ref|YP_003810221.1| Short-chain dehydrogenase [gamma proteobacterium HdN1]
 gi|301796356|emb|CBL44564.1| Short-chain dehydrogenase [gamma proteobacterium HdN1]
Length=286

 Score =  193 bits (490),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 117/273 (43%), Positives = 161/273 (59%), Gaps = 8/273 (2%)

Query  12   RDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDV  71
            +  ++  V+AITGGARGIGLATA AL   GA V+IGDID  +A ++ A +      +LDV
Sbjct  3    KKSIRGAVVAITGGARGIGLATAQALRAQGAHVSIGDIDAQLAAQAAARVGA-YSAELDV  61

Query  72   TDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL  131
             D  SFS FL++    LGP+DVL+NNAGIMP+G  VDE D ++   +DIN+ GVI G KL
Sbjct  62   RDKASFSRFLESTHSALGPVDVLINNAGIMPMGPFVDEADAISDAQIDINLRGVIHGMKL  121

Query  132  AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVL  191
                M+ RG GH++NVASLAG     G + YC +K AV   +++ R E R+ GV  S+VL
Sbjct  122  VLPEMIARGSGHIVNVASLAGRFPIPGASVYCGTKFAVCGMSEALRGELRNTGVNVSVVL  181

Query  192  PSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRF---M  248
            PS V+TEL  GT    G     P D+A A++  I +  P V    A G +    R+   +
Sbjct  182  PSRVSTELSTGTAAGNGVPTVTPEDVAQAVLDAIQYQLPEV---SAPGYLRPVSRYFNVL  238

Query  249  PRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEAR  281
            PR + +   R++  + + T  +D   R  YE R
Sbjct  239  PRWLEDAARRVVKDDRIMT-RLDRVARAPYEQR  270


>gi|118470236|ref|YP_885177.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155]
 gi|118171523|gb|ABK72419.1| putative oxidoreductase YqjQ [Mycobacterium smegmatis str. MC2 
155]
Length=286

 Score =  188 bits (478),  Expect = 7e-46, Method: Compositional matrix adjust.
 Identities = 118/277 (43%), Positives = 162/277 (59%), Gaps = 9/277 (3%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGK----  68
            D ++ K IAITG ARGIG ATA AL   GA+V IGD D A+  +  A ++L   G+    
Sbjct  2    DNIRGKTIAITGAARGIGYATAKALLAHGARVVIGDRDVAL--QESAVVELSKLGQVSGY  59

Query  69   -LDVTDPDSFSGFLDAVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVI  126
             LDVTD +SF+ FLD      G  IDVL+NNAG+MPVG  +++ +   R  +++NVYGV+
Sbjct  60   PLDVTDRESFATFLDKARTDGGGHIDVLINNAGVMPVGPFLEQSEQSIRSNIEVNVYGVL  119

Query  127  LGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVK  186
             G +LA   MV R RGH+IN+ASL+G I   G   Y  +K+AVV  + +   E    GV 
Sbjct  120  TGCQLALPDMVKRRRGHIINIASLSGVIPLPGQVVYVGAKYAVVGLSTALADEMAPYGVD  179

Query  187  FSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQR  246
             S+++P F NT+LI+GT      K  EP +IA AIV  +  PK  V V         A +
Sbjct  180  VSVIMPPFTNTDLISGTKSGGAIKPVEPEEIAAAIVKTLNKPKTHVSVPPPLRFTAQAAQ  239

Query  247  FMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
             +P +    LN+ LG ++VF  + D  KR+ YE RA+
Sbjct  240  MLPPKGRRWLNKKLGLDNVFL-EFDTAKRKAYEDRAQ  275


>gi|317509446|ref|ZP_07967064.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
 gi|316252275|gb|EFV11727.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
Length=284

 Score =  187 bits (476),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 117/274 (43%), Positives = 157/274 (58%), Gaps = 10/274 (3%)

Query  19   VIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGK-----LDVTD  73
             +AITGGARGIG AT  A    GA VA+GDID    +E+ A L  +  G+     LDVTD
Sbjct  10   TVAITGGARGIGYATGRAFAKAGASVALGDIDGGRVEEAAAQLARETGGEVRGLPLDVTD  69

Query  74   PDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAA  133
              SF+ FLDA E QLG + V+VNNAGIMP G   DE D +T R++ IN+ GV++GSKLA 
Sbjct  70   RTSFAKFLDAAEAQLGQLGVVVNNAGIMPTGLFADEDDTMTDRMVAINLTGVLIGSKLAV  129

Query  134  QRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPS  193
            +R   RG G ++N+ASLAG     GVATYCA+KHAVV F+++ R E   +    ++VLP 
Sbjct  130  RRFADRG-GRIVNIASLAGVSTHRGVATYCATKHAVVGFSEALRKELAGSTTGVTVVLPG  188

Query  194  FVNTELIAGTG---GIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPR  250
             V TEL AG+G     +      P D+A ++VG +   + +V V +  G  +     +P 
Sbjct  189  LVRTELSAGSGTPRWARPMSEVGPNDVASSVVGAVARGRDKVVVPRLLGGALGILDLLPS  248

Query  251  QVSEGLNRLLGGEHVFTDDVDMEKRRTYEARARG  284
             + E +      +  FT  VD   R  Y  R  G
Sbjct  249  GLREWVEHAARLDTAFT-AVDPAARELYHRRITG  281


>gi|120401705|ref|YP_951534.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1]
 gi|119954523|gb|ABM11528.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii 
PYR-1]
Length=292

 Score =  187 bits (476),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 116/276 (43%), Positives = 158/276 (58%), Gaps = 7/276 (2%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLD----LDMYGK  68
            D ++ K IAITG ARGIG ATA AL   GA+V IGD D A+ + + A L     +  Y  
Sbjct  2    DNIRGKTIAITGAARGIGYATAEALLRRGARVVIGDRDVALQESAVAQLTKLGPVSGY-P  60

Query  69   LDVTDPDSFSGFLDAVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVIL  127
            LDVTD DSF+ FLD      G  +DVL+NNAG+MP+G  +D+ +   R  +++N+YGVI 
Sbjct  61   LDVTDRDSFATFLDKARTDGGGHVDVLINNAGVMPIGPFLDQSEQSIRSSIEVNLYGVIT  120

Query  128  GSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKF  187
            G +LA   M+ R RGH+IN+ASL+G I   G   Y  +K  VV  + +   E    GV  
Sbjct  121  GCQLALPDMIARRRGHIINIASLSGLIPVPGQVVYVGAKFGVVGLSTALADEVAPQGVDV  180

Query  188  SMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRF  247
            S+++P F NT+LI+GT      K  EP DIA A+V  +  PK  V V         A + 
Sbjct  181  SVIMPPFTNTDLISGTTSSGALKPVEPEDIAAAVVKTLNKPKTHVSVPPPLRFTAQAAQM  240

Query  248  MPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
            +P +    L+R LG + VF  + D  KR+ YE RA+
Sbjct  241  LPPRGRRWLSRKLGLDRVFL-EFDTTKRQGYEQRAQ  275


>gi|108797508|ref|YP_637705.1| short chain dehydrogenase [Mycobacterium sp. MCS]
 gi|119866594|ref|YP_936546.1| short chain dehydrogenase [Mycobacterium sp. KMS]
 gi|126433130|ref|YP_001068821.1| short chain dehydrogenase [Mycobacterium sp. JLS]
 gi|108767927|gb|ABG06649.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS]
 gi|119692683|gb|ABL89756.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS]
 gi|126232930|gb|ABN96330.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS]
Length=287

 Score =  187 bits (476),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 120/276 (44%), Positives = 160/276 (58%), Gaps = 7/276 (2%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLD----LDMYGK  68
            D ++ K IAITG ARGIG ATA AL   GA+V IGD D A+ + + A L     +  Y  
Sbjct  2    DNIRGKTIAITGAARGIGYATAKALLARGARVVIGDRDVALQESAVAQLTKLGPVSGY-P  60

Query  69   LDVTDPDSFSGFLDAVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVIL  127
            LDVTD +SF+ FLD      G  IDVL+NNAG+MP+G  +++ +   R  +++N+YGVI 
Sbjct  61   LDVTDRESFATFLDKARTDGGGHIDVLINNAGVMPIGPFLEQSEQAIRSSIEVNLYGVIA  120

Query  128  GSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKF  187
            G +LA   MV RGRGH+IN+ASL+G I   G   Y  +K  VV  + +   E    GV  
Sbjct  121  GCQLALPDMVARGRGHIINIASLSGVIPVPGQVVYVGAKFGVVGLSAALADEVAPHGVHV  180

Query  188  SMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRF  247
            S+V+P F  TELI+GT      K  EP DIA AIV  +  PK  V V  A      A + 
Sbjct  181  SVVMPPFTRTELISGTKESGAIKPVEPEDIAAAIVKTLDKPKTHVSVPPALRFTAQAAQL  240

Query  248  MPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
            +  +    LN+ LG ++VF  D D  KR++YE RA+
Sbjct  241  LGPRGRRWLNKKLGLDNVFL-DFDTAKRKSYEDRAQ  275


>gi|169628617|ref|YP_001702266.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977]
 gi|169240584|emb|CAM61612.1| Putative short chain dehydrogenase/reductase [Mycobacterium abscessus]
Length=285

 Score =  187 bits (474),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 111/264 (43%), Positives = 155/264 (59%), Gaps = 2/264 (0%)

Query  19   VIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPDSFS  78
            V+ ITGGARGIG ATA    + GA V IGD+D+ +AKE+   +     G LDVT P+S++
Sbjct  13   VVVITGGARGIGAATARLFADRGADVWIGDVDDVVAKETANGIPNAHSGALDVTKPESWA  72

Query  79   GFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQRMVP  138
            GFLD V  + GP+D+L+NNAG+MP+G  ++E +  T  ILD+NV G + G++    +MV 
Sbjct  73   GFLDQVRAESGPVDILINNAGVMPLGGFIEENERTTDLILDVNVRGPLNGARAVLPQMVA  132

Query  139  RGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFVNTE  198
            RGRGHV+NVAS+AG++   G+ TY ASK   V  + + R EY + GV  S VLPS V TE
Sbjct  133  RGRGHVVNVASMAGKLAVPGMVTYNASKFGAVGLSVALRKEYGNTGVSVSCVLPSAVRTE  192

Query  199  LIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVT-KAAGSMIVAQRFMPRQVSEGLN  257
            L +G    KG    +P D+A AIV  +   + ++ V    A    +   F+P  V     
Sbjct  193  LASGAPLGKGMPTVDPEDVAAAIVRSVDTRRAQISVPGWLAFGWGLVDLFVPEPVERLAR  252

Query  258  RLLGGEHVFTDDVDMEKRRTYEAR  281
            RL+      T  +D+  R  Y  R
Sbjct  253  RLIDDRRALT-SLDLNARGAYIER  275


>gi|333918451|ref|YP_004492032.1| Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333480672|gb|AEF39232.1| Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [Amycolicicoccus 
subflavus DQS3-9A1]
Length=291

 Score =  185 bits (470),  Expect = 6e-45, Method: Compositional matrix adjust.
 Identities = 114/271 (43%), Positives = 159/271 (59%), Gaps = 3/271 (1%)

Query  11   IRDKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KL  69
            +   +  +V AITGGARGIG ATA AL   G  VAIGDID   AK +  ++     G  L
Sbjct  1    MNQTLSGRVAAITGGARGIGRATAEALVREGVSVAIGDIDGEAAKRTAGEIGRGTIGLPL  60

Query  70   DVTDPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGR-IVDEPDPVTRRILDINVYGVILG  128
            DVTD  S  GFLD VE  +GP+D+LVNNAG+M VG  +  E D  T+R +D+NV GV+ G
Sbjct  61   DVTDRKSVDGFLDTVEATMGPLDILVNNAGVMLVGPPLWLEDDRGTQRSIDVNVNGVVFG  120

Query  129  SKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFS  188
            +K A  R + RGRGH++NVAS AG++     A+Y  SKH VV  +++ R E R +GV  S
Sbjct  121  AKSAVPRFISRGRGHLVNVASGAGKLALPYSASYSGSKHFVVGLSEALRGELRDSGVHVS  180

Query  189  MVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFM  248
            +++P  V+TEL +G   ++G +   P  +ADAIV  +  P+  V V    G +  A+  +
Sbjct  181  LIMPGIVDTELASGHRPLRGVRTVGPEHVADAIVRALRRPRFEVFVPAELGVVSRARALV  240

Query  249  PRQVSEGLNRLLGGEHVFTDDVDMEKRRTYE  279
            PR + E    +L  + V +   D   R  Y+
Sbjct  241  PRTLWEAAMHVLKVDQVAS-GADHAAREQYQ  270


>gi|317506201|ref|ZP_07964020.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
 gi|316255447|gb|EFV14698.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
Length=289

 Score =  185 bits (469),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 115/294 (40%), Positives = 173/294 (59%), Gaps = 35/294 (11%)

Query  14   KVQDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYG-KLDVT  72
            K++ KV+ ITGGA+GIG  TA A    GAKVAIGD+D  +AK++  ++  D+    LDVT
Sbjct  7    KLRGKVVLITGGAQGIGRVTAEAFIAQGAKVAIGDLDIDLAKKAADEIGGDIIALPLDVT  66

Query  73   DPDSFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLA  132
            + + F+ F+D  E+  GPIDVLVNNAG+M VG +VDE   VT + L I++  VI GS+ A
Sbjct  67   NYEQFASFIDEAEKAFGPIDVLVNNAGVMIVGDLVDESQRVTDKQLSIDLNSVIFGSREA  126

Query  133  AQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLP  192
            A+RM+PR  GH++N+AS+AG+I   G++TY A+K+ VV F+++ R E     V+ + ++P
Sbjct  127  AKRMIPRRTGHIVNIASIAGKIGVAGLSTYNAAKYGVVGFSEALRFELSQHNVEVTTIMP  186

Query  193  SFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTK-----AAGS-------  240
            SF+ T LI G             ++ DA++  IV P+P  +V +     AAG        
Sbjct  187  SFIKTGLIDGI------------NVEDALILKIVRPQPPEKVAEAIVVSAAGRGRNRWVP  234

Query  241  --------MIVAQRFMPRQVSEGLNRLLGGEHVFT-DDVDMEKRRTYEARARGE  285
                    ++   R+ PR ++  + R+LG   V T   VD+  R+ Y  R  G+
Sbjct  235  GFVTALDPLLAMVRWSPR-LTVFVTRVLGLSTVMTGGGVDVSARKKYIERTTGQ  287


>gi|333989010|ref|YP_004521624.1| short-chain dehydrogenase [Mycobacterium sp. JDM601]
 gi|333484978|gb|AEF34370.1| short-chain type dehydrogenase [Mycobacterium sp. JDM601]
Length=284

 Score =  184 bits (467),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 118/277 (43%), Positives = 156/277 (57%), Gaps = 9/277 (3%)

Query  13   DKVQDKVIAITGGARGIGLATAAALHNLGAKVAIGD-----IDEAMAKESGADLDLDMYG  67
            D ++ K IAITG ARGIGLATA AL   GA+V IGD     ++EA+ K+ GA   +  + 
Sbjct  2    DNIRGKTIAITGAARGIGLATATALLRRGARVVIGDRDTHALNEAV-KQLGAGSPVTGH-  59

Query  68   KLDVTDPDSFSGFLDAVERQ-LGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVI  126
             LDVTD +SFS FLD       G IDVL+NNAG+MPVG  +++     R   ++N YGV+
Sbjct  60   PLDVTDRESFSMFLDKARADGDGRIDVLINNAGVMPVGPFLEQTPETFRSATEVNFYGVL  119

Query  127  LGSKLAAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVK  186
             G +L    MV R  GH+IN+AS+AG +   G   Y  +K AVV  T +   E+   GV 
Sbjct  120  NGCQLVLPEMVKRRSGHIINIASMAGIVAVPGQVLYAGTKFAVVGLTTAMADEFAPQGVA  179

Query  187  FSMVLPSFVNTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQR  246
             S VLP+F NTELI+GT      K  EP D+A A+V ++  PK  V V        +   
Sbjct  180  VSAVLPTFTNTELISGTTPSAAQKPVEPQDVAAAVVKVLDKPKTLVSVPSFGRRTAILAT  239

Query  247  FMPRQVSEGLNRLLGGEHVFTDDVDMEKRRTYEARAR  283
             +P +    LN+  G   VF   +D E RR YE RA+
Sbjct  240  LLPDRGRRWLNKKTGNNTVFL-QLDTEARRAYEDRAQ  275


>gi|254447794|ref|ZP_05061259.1| 3-hydroxybutyrate dehydrogenase [gamma proteobacterium HTCC5015]
 gi|198262574|gb|EDY86854.1| 3-hydroxybutyrate dehydrogenase [gamma proteobacterium HTCC5015]
Length=280

 Score =  183 bits (465),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 106/266 (40%), Positives = 156/266 (59%), Gaps = 2/266 (0%)

Query  16   QDKVIAITGGARGIGLATAAALHNLGAKVAIGDIDEAMAKESGADLDLDMYGKLDVTDPD  75
            ++ V+ +TGGARGIGLATA  L +LGA+V I DID  +A++   DL   +   LD+ D  
Sbjct  8    KNAVVVVTGGARGIGLATAKQLLDLGARVVIADIDSELAQKEAHDLG-ALAVTLDIRDHQ  66

Query  76   SFSGFLDAVERQLGPIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKLAAQR  135
            S    +D VE+QLGPID  +NNAGIMP+G  V+EP  +++  ++IN+ G+I   K+    
Sbjct  67   SIQQCIDTVEKQLGPIDGWINNAGIMPMGAFVEEPSELSQTQIEINLIGLIAACKMVLPG  126

Query  136  MVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYRSAGVKFSMVLPSFV  195
            M+ R RG ++NVASLAG     G A Y A+K  VV FT++ R EYR +GV  + VLPS V
Sbjct  127  MLSRKRGRIVNVASLAGRFGLPGAAVYSATKFGVVGFTEALREEYRDSGVHIASVLPSKV  186

Query  196  NTELIAGTGGIKGFKNAEPADIADAIVGLIVHPKPRVRVTKAAGSMIVAQRFMPRQVSEG  255
             TEL +GT   +      P  +AD I+  +      V V ++  ++  A   +P +V+  
Sbjct  187  LTELSSGTDEGRLIPAVTPEQVADGIITALSGKADEVVVPQSLSAVASAYGALPTRVARR  246

Query  256  LNRLLGGEHVFTDDVDMEKRRTYEAR  281
              RL+  +H   + +D   R+ Y +R
Sbjct  247  FRRLI-DDHRILNSLDHNLRKGYTSR  271



Lambda     K      H
   0.319    0.138    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 461491158592


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40