BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1880c Length=438 Score E Sequences producing significant alignments: (Bits) Value gi|345462005|ref|NP_216396.2| cytochrome p450 140 CYP140 [Mycoba... 878 0.0 gi|31793071|ref|NP_855564.1| cytochrome p450 140 CYP140 [Mycobac... 876 0.0 gi|289757987|ref|ZP_06517365.1| cytochrome p450 140 CYP140 [Myco... 874 0.0 gi|306808162|ref|ZP_07444830.1| cytochrome P450 140 cyp140 [Myco... 874 0.0 gi|298525375|ref|ZP_07012784.1| cytochrome P450 140 [Mycobacteri... 873 0.0 gi|15841350|ref|NP_336387.1| P450 heme-thiolate protein [Mycobac... 857 0.0 gi|240170526|ref|ZP_04749185.1| cytochrome P450 140A5 Cyp140A5 [... 730 0.0 gi|183982774|ref|YP_001851065.1| cytochrome P450 140A5 Cyp140A5 ... 723 0.0 gi|118618378|ref|YP_906710.1| cytochrome P450 140A5 Cyp140A5 [My... 719 0.0 gi|254819300|ref|ZP_05224301.1| P450 heme-thiolate protein [Myco... 691 0.0 gi|342859529|ref|ZP_08716182.1| cytochrome P450 [Mycobacterium c... 690 0.0 gi|118466270|ref|YP_882009.1| P450 heme-thiolate protein [Mycoba... 673 0.0 gi|41407701|ref|NP_960537.1| hypothetical protein MAP1603c [Myco... 671 0.0 gi|254775301|ref|ZP_05216817.1| P450 heme-thiolate protein [Myco... 671 0.0 gi|296164899|ref|ZP_06847455.1| P450 heme-thiolate protein [Myco... 670 0.0 gi|336457541|gb|EGO36547.1| cytochrome P450 [Mycobacterium avium... 663 0.0 gi|120401616|ref|YP_951445.1| cytochrome P450 [Mycobacterium van... 594 8e-168 gi|145220892|ref|YP_001131570.1| cytochrome P450 [Mycobacterium ... 587 2e-165 gi|108797413|ref|YP_637610.1| cytochrome P450 [Mycobacterium sp.... 573 1e-161 gi|126433032|ref|YP_001068723.1| cytochrome P450 [Mycobacterium ... 572 4e-161 gi|118468531|ref|YP_885089.1| P450 heme-thiolate protein [Mycoba... 556 2e-156 gi|49146137|ref|YP_025575.1| cytochrome p450 150 cyp150 [Mycobac... 546 2e-153 gi|300785252|ref|YP_003765543.1| cytochrome P450 [Amycolatopsis ... 396 3e-108 gi|326328979|ref|ZP_08195309.1| P450 heme-thiolate protein [Noca... 381 1e-103 gi|331695871|ref|YP_004332110.1| Linalool 8-monooxygenase [Pseud... 375 9e-102 gi|284990983|ref|YP_003409537.1| cytochrome P450 [Geodermatophil... 363 3e-98 gi|324997266|ref|ZP_08118378.1| cytochrome P450 [Pseudonocardia ... 360 3e-97 gi|41408131|ref|NP_960967.1| hypothetical protein MAP2033 [Mycob... 349 6e-94 gi|336461806|gb|EGO40664.1| cytochrome P450 [Mycobacterium avium... 349 7e-94 gi|254774866|ref|ZP_05216382.1| P450 heme-thiolate protein [Myco... 348 1e-93 gi|309812503|ref|ZP_07706256.1| putative cytochrome P450 107B1 [... 348 1e-93 gi|118463470|ref|YP_881366.1| P450 heme-thiolate protein [Mycoba... 347 2e-93 gi|326329287|ref|ZP_08195612.1| P450 heme-thiolate protein [Noca... 343 5e-92 gi|54026614|ref|YP_120856.1| cytochrome P450 monooxygenase [Noca... 338 8e-91 gi|157885004|gb|ABV91294.1| probable cytochrome P450 [Streptomyc... 333 4e-89 gi|254818682|ref|ZP_05223683.1| P450 heme-thiolate protein [Myco... 330 2e-88 gi|342857339|ref|ZP_08713995.1| hypothetical protein MCOL_00635 ... 330 4e-88 gi|333988977|ref|YP_004521591.1| cytochrome P450 [Mycobacterium ... 320 2e-85 gi|296141326|ref|YP_003648569.1| cytochrome P450 [Tsukamurella p... 317 3e-84 gi|284993031|ref|YP_003411585.1| cytochrome P450 [Geodermatophil... 314 2e-83 gi|120406468|ref|YP_956297.1| cytochrome P450 [Mycobacterium van... 313 4e-83 gi|169631530|ref|YP_001705179.1| putative cytochrome P450 [Mycob... 306 4e-81 gi|296394068|ref|YP_003658952.1| cytochrome P450 [Segniliparus r... 288 1e-75 gi|342859660|ref|ZP_08716313.1| putative cytochrome P450 [Mycoba... 279 8e-73 gi|169631531|ref|YP_001705180.1| putative cytochrome P450 [Mycob... 246 5e-63 gi|256397594|ref|YP_003119158.1| cytochrome P450 [Catenulispora ... 242 9e-62 gi|134102386|ref|YP_001108047.1| cytochrome p450-like enzyme [Sa... 236 4e-60 gi|37521511|ref|NP_924888.1| cytochrome P-450 like protein [Gloe... 236 4e-60 gi|15828128|ref|NP_302391.1| cytochrome p450 [Mycobacterium lepr... 233 7e-59 gi|297561171|ref|YP_003680145.1| cytochrome P450 [Nocardiopsis d... 228 1e-57 >gi|345462005|ref|NP_216396.2| cytochrome p450 140 CYP140 [Mycobacterium tuberculosis H37Rv] Length=449 Score = 878 bits (2269), Expect = 0.0, Method: Compositional matrix adjust. Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN Sbjct 12 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 71 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT Sbjct 72 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 131 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG Sbjct 132 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 191 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS Sbjct 192 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 251 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP Sbjct 252 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 311 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR Sbjct 312 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 371 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR Sbjct 372 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 431 Query 421 GWSTLPVTLGPARSMVSP 438 GWSTLPVTLGPARSMVSP Sbjct 432 GWSTLPVTLGPARSMVSP 449 >gi|31793071|ref|NP_855564.1| cytochrome p450 140 CYP140 [Mycobacterium bovis AF2122/97] gi|121637784|ref|YP_978007.1| putative cytochrome p450 140 CYP140 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148661686|ref|YP_001283209.1| putative cytochrome p450 140 CYP140 [Mycobacterium tuberculosis H37Ra] 71 more sequence titles Length=438 Score = 876 bits (2264), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/438 (99%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN Sbjct 1 MKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT Sbjct 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG Sbjct 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS Sbjct 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP Sbjct 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR Sbjct 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR Sbjct 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVSP 438 GWSTLPVTLGPARSMVSP Sbjct 421 GWSTLPVTLGPARSMVSP 438 >gi|289757987|ref|ZP_06517365.1| cytochrome p450 140 CYP140 [Mycobacterium tuberculosis T85] gi|289713551|gb|EFD77563.1| cytochrome p450 140 CYP140 [Mycobacterium tuberculosis T85] Length=438 Score = 874 bits (2259), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN Sbjct 1 MKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT Sbjct 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG Sbjct 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS Sbjct 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQIAESGDNETQLDETELRAIAGLVLVAGFET VNLLGNGIRMLLDTPEHLATLRQHP Sbjct 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETAVNLLGNGIRMLLDTPEHLATLRQHP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR Sbjct 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR Sbjct 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVSP 438 GWSTLPVTLGPARSMVSP Sbjct 421 GWSTLPVTLGPARSMVSP 438 >gi|306808162|ref|ZP_07444830.1| cytochrome P450 140 cyp140 [Mycobacterium tuberculosis SUMu007] gi|306967976|ref|ZP_07480637.1| cytochrome P450 140 cyp140 [Mycobacterium tuberculosis SUMu009] gi|308345475|gb|EFP34326.1| cytochrome P450 140 cyp140 [Mycobacterium tuberculosis SUMu007] gi|308354417|gb|EFP43268.1| cytochrome P450 140 cyp140 [Mycobacterium tuberculosis SUMu009] Length=438 Score = 874 bits (2258), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN Sbjct 1 MKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT Sbjct 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG Sbjct 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS Sbjct 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTV LLGNGIRMLLDTPEHLATLRQHP Sbjct 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVTLLGNGIRMLLDTPEHLATLRQHP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR Sbjct 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR Sbjct 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVSP 438 GWSTLPVTLGPARSMVSP Sbjct 421 GWSTLPVTLGPARSMVSP 438 >gi|298525375|ref|ZP_07012784.1| cytochrome P450 140 [Mycobacterium tuberculosis 94_M4241A] gi|298495169|gb|EFI30463.1| cytochrome P450 140 [Mycobacterium tuberculosis 94_M4241A] Length=438 Score = 873 bits (2256), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN Sbjct 1 MKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT Sbjct 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG Sbjct 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLE HLQQLRHAPGDDLMS Sbjct 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEEHLQQLRHAPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP Sbjct 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR Sbjct 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR Sbjct 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVSP 438 GWSTLPVTLGPARSMVSP Sbjct 421 GWSTLPVTLGPARSMVSP 438 >gi|15841350|ref|NP_336387.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|13881583|gb|AAK46201.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] Length=429 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/429 (100%), Positives = 429/429 (100%), Gaps = 0/429 (0%) Query 10 MHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLA 69 MHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLA Sbjct 1 MHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLA 60 Query 70 HDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAV 129 HDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAV Sbjct 61 HDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAV 120 Query 130 FTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRV 189 FTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRV Sbjct 121 FTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRV 180 Query 190 LEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESG 249 LEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESG Sbjct 181 LEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESG 240 Query 250 DNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEE 309 DNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEE Sbjct 241 DNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEE 300 Query 310 ILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAG 369 ILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAG Sbjct 301 ILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAG 360 Query 370 RHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTL 429 RHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTL Sbjct 361 RHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTL 420 Query 430 GPARSMVSP 438 GPARSMVSP Sbjct 421 GPARSMVSP 429 >gi|240170526|ref|ZP_04749185.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium kansasii ATCC 12478] Length=438 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/437 (83%), Positives = 397/437 (91%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KD+LHWLA+HGVIRG+A +G+RRG+LQARLIADPAVA +PVPFYDE+R HG LVR R N Sbjct 1 MKDRLHWLALHGVIRGMAHVGVRRGELQARLIADPAVAANPVPFYDELRRHGRLVRTRVN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 LTVDH+L HD+LRSDDF+V+S GENLP PLRWLERRTR +QLHPLR PSLLAVEPPDHT Sbjct 61 CLTVDHQLGHDILRSDDFQVISLGENLPAPLRWLERRTRDNQLHPLRPPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT+RAV+ALRD VEQTAINLLD+ A QPG+VDVVGRYCSQLPI VISEILG Sbjct 121 RYRKTVSAVFTARAVAALRDRVEQTAINLLDQLAAQPGVVDVVGRYCSQLPIAVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VP HDR RVLEFGELAAPSLDIG+P+RQY RVQ+G++GF+ WL HL QLR APGDDLMS Sbjct 181 VPAHDRRRVLEFGELAAPSLDIGVPYRQYQRVQRGVKGFNAWLVSHLAQLRRAPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLI+ AESGD ET LD+ EL A+AGLVLVAGFETTVNLLGNGIRMLLD PEHL TLR+ P Sbjct 241 QLIRTAESGDPETHLDDDELHAVAGLVLVAGFETTVNLLGNGIRMLLDMPEHLETLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 +LWPNTVEEILRLDSPVQLTARVA DVE+AGV I RGE+VVI LA ANRDP+VFPDPHR Sbjct 301 DLWPNTVEEILRLDSPVQLTARVARTDVELAGVPINRGEMVVICLAGANRDPSVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIER NAGRHLAFSTGRHFCLGAALARAEGEVGLRTFF+RFP+VRAAGAGSRRDTRVLR Sbjct 361 FDIERANAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFERFPEVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWSTLPVTLGPAR++ + Sbjct 421 GWSTLPVTLGPARALAA 437 >gi|183982774|ref|YP_001851065.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium marinum M] gi|183176100|gb|ACC41210.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium marinum M] Length=438 Score = 723 bits (1866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/437 (82%), Positives = 394/437 (91%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHW AMHGVIRG+A IG+RRG+L+ARLIADPAVA +P PF+DE+R HG +VR R N Sbjct 1 MKDKLHWFAMHGVIRGMANIGLRRGELEARLIADPAVAANPGPFHDELRRHGRMVRTRVN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVD++LAHD+LRSDDF +SFGENLP PLRWLERRTR +QLHPLR PSLLAVEPPDHT Sbjct 61 YLTVDYQLAHDVLRSDDFHTISFGENLPGPLRWLERRTRDEQLHPLRPPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAV+ALRD VEQTA +LLD+ A++PG+VDVVG+YCSQLPI+VISEILG Sbjct 121 RYRKTVSAVFTSRAVAALRDRVEQTANSLLDQLAQRPGVVDVVGQYCSQLPIMVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLE+GELAAPSLDIG+P+RQY R+QQGI GF+ WL HL+QLR PGDDLMS Sbjct 181 VPEQDRGRVLEYGELAAPSLDIGVPYRQYRRIQQGITGFNSWLTAHLEQLRRNPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLI++AESGD T LDE+ELRA+AGLVLVAGFETTVNLLGNGIRMLLD PE L TLRQ P Sbjct 241 QLIRVAESGDAGTYLDESELRAVAGLVLVAGFETTVNLLGNGIRMLLDAPEQLETLRQRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRLDSPVQLTARVA DVE+A I RGE+VV YLA ANRDPAVFP+PHR Sbjct 301 ELWPNAVEEILRLDSPVQLTARVARTDVEIASWPINRGEMVVAYLAGANRDPAVFPNPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FD+ER NAGRHLAFSTGRHFCLGAALARAEGEVGLRTFF+RFPDVRAAGAGSRRDTRVLR Sbjct 361 FDVERANAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFERFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWSTLPVTLGPAR++ + Sbjct 421 GWSTLPVTLGPARALAA 437 >gi|118618378|ref|YP_906710.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium ulcerans Agy99] gi|118570488|gb|ABL05239.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium ulcerans Agy99] Length=438 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/437 (81%), Positives = 393/437 (90%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +KDKLHW AMHGVIRG+A IG+RRG+L+ARLIADPAVA +P PF+DE+R HG +VR R N Sbjct 1 MKDKLHWFAMHGVIRGMANIGLRRGELEARLIADPAVAANPGPFHDELRRHGRMVRTRVN 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLTVD++LAHD+LRSDDF +SFGENLP PLRWLERRTR +QLHPLR PSLLAVEPPDHT Sbjct 61 YLTVDYQLAHDVLRSDDFHTISFGENLPGPLRWLERRTRDEQLHPLRPPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFTSRAV+ALRD VEQTA +LLD+ A++PG+VDVVG+YCSQLPI+VISEILG Sbjct 121 RYRKTVSAVFTSRAVAALRDRVEQTANSLLDQLAQRPGVVDVVGQYCSQLPIMVISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLE+GELAAPSLDIG+ +RQY R+QQGI GF+ WL HL+QLR PGDDLMS Sbjct 181 VPEQDRGRVLEYGELAAPSLDIGVTYRQYRRIQQGITGFNSWLTAHLEQLRRNPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLI++AESGD T LD++ELRAIAGLVLVAGFETTVNLLGNGIRMLLD PE L TLRQ P Sbjct 241 QLIRVAESGDAGTYLDKSELRAIAGLVLVAGFETTVNLLGNGIRMLLDAPEQLETLRQRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRLDSPVQLTARVA DVE+A I RGE+VV YLA ANRDPAVFP+PHR Sbjct 301 ELWPNAVEEILRLDSPVQLTARVARTDVEIASWPINRGEMVVAYLAGANRDPAVFPNPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FD+ER NAGRHLAFSTGRHFCLGAALARAEGEVGLRTFF+RFPDVRAAGAGSRRDTRVLR Sbjct 361 FDVERANAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFERFPDVRAAGAGSRRDTRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWSTLPVTLGPAR++ + Sbjct 421 GWSTLPVTLGPARALAA 437 >gi|254819300|ref|ZP_05224301.1| P450 heme-thiolate protein [Mycobacterium intracellulare ATCC 13950] Length=440 Score = 691 bits (1782), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/437 (78%), Positives = 376/437 (87%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA G RRGD+QARLIADPAVA DPV FYDEVR+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAAYGARRGDVQARLIADPAVAADPVRFYDEVRARGKLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRSDDFRVV FG NLP PLRWLERRTR D LHPLR PSLLAVEPPDHT Sbjct 61 YLTADHALAHELLRSDDFRVVIFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALR+ VEQTA +LL+R + G+VD+VGRYC+QLP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRERVEQTAADLLERLTGESGVVDIVGRYCAQLPVSIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DRPRVLEFGELAAPSLDIG+PWRQY VQ GI GF WL HLQ+LR P D++MS Sbjct 181 VPESDRPRVLEFGELAAPSLDIGLPWRQYRSVQDGIAGFSSWLAEHLQRLRREPSDNVMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET L+E EL+AIAGLVL AGFETTVNLLGNGIR LLD PEHL LR+ P Sbjct 241 QLIQTAESGSAETYLNENELQAIAGLVLAAGFETTVNLLGNGIRTLLDAPEHLDALRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVE+AG ++ RG++V++YLAAANRDPAVF DPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARMARGDVEIAGHQVARGDLVLVYLAAANRDPAVFSDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFS GRHFCLGAALARAEGEVGLRTFFDRFP+VRAAGAGSRR+TRVLR Sbjct 361 FDIERPNAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFDRFPEVRAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LP LGPARSM + Sbjct 421 GWSSLPAALGPARSMAA 437 >gi|342859529|ref|ZP_08716182.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342132661|gb|EGT85881.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=440 Score = 690 bits (1780), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/437 (79%), Positives = 379/437 (87%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA+G RRGD+QARLIADPAVA DPV +YDEVR+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAALGARRGDVQARLIADPAVAADPVRYYDEVRARGKLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRSDDFRV+ FG NLP PLRWLERRTR D LHPLR PSLLAVEPPDHT Sbjct 61 YLTADHALAHELLRSDDFRVLIFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPDHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALRD VEQTA LLDR A + G+VD+V RYC+QLP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRDRVEQTAAELLDRLAGELGVVDIVRRYCAQLPVSIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE +R RVLEFGELAAPSLDIG+PWRQY VQ GI GF WL+ HLQQLR P D+LMS Sbjct 181 VPEAERRRVLEFGELAAPSLDIGLPWRQYRSVQDGIAGFSSWLDEHLQQLRLDPSDNLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET L+E EL+AIAGLVL AGFETTVNLLGNGIRMLLD P+HL TLR+ P Sbjct 241 QLIQTAESGSAETYLNEKELQAIAGLVLAAGFETTVNLLGNGIRMLLDAPQHLDTLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVE+AG +++RG++V++YLAAANRDPAVFPDPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARLARADVEIAGRQLERGDLVLVYLAAANRDPAVFPDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIER NAGRHLAFS GRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRR+TRVLR Sbjct 361 FDIERENAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LPV LGP RSM + Sbjct 421 GWSSLPVNLGPVRSMAA 437 >gi|118466270|ref|YP_882009.1| P450 heme-thiolate protein [Mycobacterium avium 104] gi|118167557|gb|ABK68454.1| P450 heme-thiolate protein [Mycobacterium avium 104] Length=450 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/437 (78%), Positives = 376/437 (87%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA+G RRGD+ ARLIADPAVA DP FYDE R+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAALGARRGDVHARLIADPAVAADPARFYDEARARGTLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRS+DFRV+ FG NLP PLRWLERRTR D LHPLR PSLLAVEPP+HT Sbjct 61 YLTADHALAHELLRSEDFRVLVFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPEHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALRD VE+TA LLD+ PG+VD+VGRYCSQLP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRDRVERTAAELLDQLTGGPGVVDIVGRYCSQLPVAIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLEFGELAAPSLDIG+PWRQY VQ+GI GF WL GHLQQLR P D+LMS Sbjct 181 VPEQDRSRVLEFGELAAPSLDIGLPWRQYRSVQRGIAGFSSWLAGHLQQLRSNPSDNLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET LDETEL AIAGLVL AGFETTVNLLGNGIRMLLD PEHL TLR+ P Sbjct 241 QLIQTAESGSAETYLDETELAAIAGLVLAAGFETTVNLLGNGIRMLLDAPEHLDTLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVEVAG ++ RG++V++YLAAANRDPAVF DPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARMALNDVEVAGRQLHRGDLVLVYLAAANRDPAVFGDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFS GRHFCLGAALARAEGEVGLRTFF+RFP+ RAAGAGSRR+TRVLR Sbjct 361 FDIERPNAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFERFPEARAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LPV LGPARS+ + Sbjct 421 GWSSLPVRLGPARSLAA 437 >gi|41407701|ref|NP_960537.1| hypothetical protein MAP1603c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396054|gb|AAS03920.1| hypothetical protein MAP_1603c [Mycobacterium avium subsp. paratuberculosis K-10] Length=450 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/437 (78%), Positives = 375/437 (86%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA+G RRGD+ ARLIADPAVA DP FYDE R+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAALGARRGDVHARLIADPAVAADPARFYDEARARGTLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRS+DFRV+ FG NLP PLRWLERRTR D LHPLR PSLLAVEPP+HT Sbjct 61 YLTADHALAHELLRSEDFRVLVFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPEHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALRD VE+TA LLD+ PG+VD+VGRYCSQLP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRDRVERTAAELLDQLTGGPGVVDIVGRYCSQLPVAIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLEFGELAAPSLDIG+PWRQY VQ+GI GF WL GHLQQLR P D+LMS Sbjct 181 VPEQDRSRVLEFGELAAPSLDIGLPWRQYRSVQRGIAGFSSWLAGHLQQLRSNPSDNLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET LDETEL AIAGLVL AGFETTVNLLG GIRMLLD PEHL TLR+ P Sbjct 241 QLIQTAESGSAETYLDETELAAIAGLVLAAGFETTVNLLGKGIRMLLDAPEHLDTLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVEVAG ++ RG++V++YLAAANRDPAVF DPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARMALNDVEVAGRQLHRGDLVLVYLAAANRDPAVFGDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFS GRHFCLGAALARAEGEVGLRTFF+RFP+ RAAGAGSRR+TRVLR Sbjct 361 FDIERPNAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFERFPEARAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LPV LGPARS+ + Sbjct 421 GWSSLPVRLGPARSLAA 437 >gi|254775301|ref|ZP_05216817.1| P450 heme-thiolate protein [Mycobacterium avium subsp. avium ATCC 25291] Length=450 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/437 (78%), Positives = 375/437 (86%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA G RRGD+ ARLIADPAVA DP FYDE R+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAAQGARRGDVHARLIADPAVAADPARFYDEARARGTLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRS+DFRV+ FG NLP PLRWLERRTR D LHPLR PSLLAVEPP+HT Sbjct 61 YLTADHALAHELLRSEDFRVLVFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPEHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALRD VE+TA LLD+ PG+VD+VGRYCSQLP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRDRVERTAAELLDQLTGGPGVVDIVGRYCSQLPVAIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLEFGELAAPSLDIG+PWRQY VQ+GI GF WL GHLQQLR P D+LMS Sbjct 181 VPEQDRSRVLEFGELAAPSLDIGLPWRQYRSVQRGIAGFSSWLAGHLQQLRSNPSDNLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET LDETEL AIAGLVL AGFETTVNLLGNGIRMLLD PEHL TLR+ P Sbjct 241 QLIQTAESGSAETYLDETELAAIAGLVLAAGFETTVNLLGNGIRMLLDAPEHLDTLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVEVAG ++ RG++V++YLAAANRDPAVF DPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARMALDDVEVAGRQLHRGDLVLVYLAAANRDPAVFGDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFS GRHFCLGAALARAEGEVGLRTFF+RFP+ RAAGAGSRR+TRVLR Sbjct 361 FDIERPNAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFERFPEARAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LPV LGPARS+ + Sbjct 421 GWSSLPVRLGPARSLAA 437 >gi|296164899|ref|ZP_06847455.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899741|gb|EFG79191.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=447 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/438 (77%), Positives = 380/438 (87%), Gaps = 3/438 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 VK++LHWLAMHG IRG+A +G+RRGDL ARLIADP VA +PVPFYDE+R+ G LV+ R + Sbjct 5 VKERLHWLAMHGFIRGVATLGVRRGDLHARLIADPTVAANPVPFYDELRAAGPLVKGRVS 64 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRSDDFRV+ FG NLP PL+WLER TR D LHPLR PSLLAVEPPDHT Sbjct 65 YLTADHALAHELLRSDDFRVLVFGANLPGPLKWLERHTRDDLLHPLRAPSLLAVEPPDHT 124 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPG---IVDVVGRYCSQLPIVVISE 177 RYRKTVSAVFT RAV+ALRD VEQTA LLD+ A + G +VDVVGRYCSQLP+ +IS+ Sbjct 125 RYRKTVSAVFTPRAVAALRDRVEQTAAALLDQLAAESGASRVVDVVGRYCSQLPVAIISD 184 Query 178 ILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDD 237 ILGVPE DR RVLEFGELAAPSLDIG+ W+QY VQ+G+ GF WL+GHL +LR AP D+ Sbjct 185 ILGVPERDRRRVLEFGELAAPSLDIGLTWQQYRTVQRGLAGFSSWLDGHLGRLRSAPSDN 244 Query 238 LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 +MSQLI+IAESG ET LDE EL+AIAGLVL AGFETTVNLLGNGIRMLLD P+ L TLR Sbjct 245 VMSQLIEIAESGSAETHLDENELKAIAGLVLAAGFETTVNLLGNGIRMLLDAPDRLDTLR 304 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 + PELWPN VEEILRL+SPVQLTARVA +DVE+ G I+RG++V++YLAAANRDP+VF + Sbjct 305 RRPELWPNAVEEILRLESPVQLTARVALKDVELGGKHIRRGDLVLVYLAAANRDPSVFAE 364 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 PHRFDIER NAGRHLAFS GRHFCLGAALARAEGEVGLRTFFDRFP+VRAAGAGSRRDTR Sbjct 365 PHRFDIERANAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFDRFPEVRAAGAGSRRDTR 424 Query 418 VLRGWSTLPVTLGPARSM 435 VLRGWS+LPV LGPARSM Sbjct 425 VLRGWSSLPVALGPARSM 442 >gi|336457541|gb|EGO36547.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=450 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/437 (77%), Positives = 373/437 (86%), Gaps = 0/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K++LHW AMHG IRG AA+G RRGD+ ARLIADPAVA DP FYDE R+ G LV+ R Sbjct 1 MKERLHWFAMHGFIRGAAALGARRGDVHARLIADPAVAADPARFYDEARARGTLVKGRVA 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 YLT DH LAH+LLRS+DFRV+ FG NLP PLRWLERRTR D LHPLR PSLLAVEPP+HT Sbjct 61 YLTADHALAHELLRSEDFRVLVFGSNLPAPLRWLERRTRDDLLHPLRAPSLLAVEPPEHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRKTVSAVFT RAV+ALRD VE+TA LLD+ PG+VD+VGRYCS LP+ +ISEILG Sbjct 121 RYRKTVSAVFTPRAVAALRDRVERTAAELLDQLTGGPGVVDIVGRYCSPLPVAIISEILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VPE DR RVLEFGELAAPSLDIG+PWRQY V++GI GF WL GHLQQLR P D+LMS Sbjct 181 VPEQDRSRVLEFGELAAPSLDIGLPWRQYRSVRRGIAGFSSWLAGHLQQLRSNPSDNLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 QLIQ AESG ET LDETEL AIAGLVL AGFETTV LLG GIRMLLD PEHL TLR+ P Sbjct 241 QLIQTAESGSAETYLDETELAAIAGLVLAAGFETTVKLLGKGIRMLLDAPEHLDTLRRRP 300 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELWPN VEEILRL+SPVQLTAR+A DVEVAG ++ RG++V++YLAAANRDPAVF DPHR Sbjct 301 ELWPNAVEEILRLESPVQLTARMALNDVEVAGRQLHRGDLVLVYLAAANRDPAVFGDPHR 360 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDIERPNAGRHLAFS GRHFCLGAALARAEGEVGLRTFF+RFP+ RAAGAGSRR+TRVLR Sbjct 361 FDIERPNAGRHLAFSGGRHFCLGAALARAEGEVGLRTFFERFPEARAAGAGSRRETRVLR 420 Query 421 GWSTLPVTLGPARSMVS 437 GWS+LPV LGPARS+ + Sbjct 421 GWSSLPVRLGPARSLAA 437 >gi|120401616|ref|YP_951445.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119954434|gb|ABM11439.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=443 Score = 594 bits (1532), Expect = 8e-168, Method: Compositional matrix adjust. Identities = 289/437 (67%), Positives = 352/437 (81%), Gaps = 1/437 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRG-DLQARLIADPAVATDPVPFYDEVRSHGALVRNRA 59 ++ ++ WLA+HGVIRG++ + +RRG D QARLIADPAV DP F DE+R G ++R RA Sbjct 5 LQQRIRWLALHGVIRGLSKVAVRRGQDPQARLIADPAVRADPAAFADELRGRGPVIRCRA 64 Query 60 NYLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDH 119 +TVDH++ +++LRSDDFRV S G LP PL+W+ R+T LHP+ PSLL++EPPDH Sbjct 65 VLMTVDHQVVNEILRSDDFRVSSLGAGLPKPLQWINRKTHPGLLHPIEPPSLLSIEPPDH 124 Query 120 TRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEIL 179 TR RK VS+VFT+RAV+ALR+ V+QTA +LLD + G+VD+V RYCSQLP+ VIS+IL Sbjct 125 TRCRKLVSSVFTTRAVAALRERVQQTANDLLDDLERESGVVDIVERYCSQLPVAVISDIL 184 Query 180 GVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLM 239 GVPE DR +L FGEL APSLDIG+ WRQY +V +G+ GF+ WL GH+ +LR PGDDLM Sbjct 185 GVPERDRRHILHFGELGAPSLDIGLSWRQYTQVHEGLVGFNEWLGGHMDELRRNPGDDLM 244 Query 240 SQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQH 299 SQLIQ +++ D ++L + EL+A AGLVL AGFETTVNLLGNGIRMLL+TP HL TL Sbjct 245 SQLIQASQAADEGSRLTDRELQATAGLVLAAGFETTVNLLGNGIRMLLETPGHLETLAAR 304 Query 300 PELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPH 359 PELWPN VEEILRLDSPVQ++AR A RDV V G IKRGE+V+++LA ANRDP VF DPH Sbjct 305 PELWPNAVEEILRLDSPVQMSARFARRDVTVGGTEIKRGELVILHLAGANRDPEVFTDPH 364 Query 360 RFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVL 419 RFDIER NAGRHL+FS GRHFCLGAALARAEGEVGLRTFF+R+PD R AG GSRRDTRVL Sbjct 365 RFDIERDNAGRHLSFSGGRHFCLGAALARAEGEVGLRTFFERYPDARLAGQGSRRDTRVL 424 Query 420 RGWSTLPVTLGPARSMV 436 RGWSTLP+TLG AR+ + Sbjct 425 RGWSTLPITLGTARAAL 441 >gi|145220892|ref|YP_001131570.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|145213378|gb|ABP42782.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] Length=444 Score = 587 bits (1512), Expect = 2e-165, Method: Compositional matrix adjust. Identities = 290/433 (67%), Positives = 346/433 (80%), Gaps = 1/433 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRR-GDLQARLIADPAVATDPVPFYDEVRSHGALVRNRA 59 ++ ++ WLA+HGVIRG++ + RR GD QARLIADP DP F DEVR+ +VR RA Sbjct 6 LRQRIRWLALHGVIRGLSKLAARRSGDPQARLIADPEARNDPAAFADEVRTGDPVVRCRA 65 Query 60 NYLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDH 119 LTVDH+ A+++LRSDDFRV S G LP PLRW+ R+T LHP+ PSLL++EPPDH Sbjct 66 VLLTVDHQAANEILRSDDFRVSSLGAGLPAPLRWVNRKTHPGLLHPIEPPSLLSIEPPDH 125 Query 120 TRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEIL 179 TR RK VS+VFT+RAV+ALRD V+ TA LLD + G+VD+V RYCSQLP+ VIS+IL Sbjct 126 TRCRKLVSSVFTTRAVNALRDRVQLTADQLLDDLERESGVVDIVERYCSQLPVAVISDIL 185 Query 180 GVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLM 239 GVPE DR +L FGEL APSLDIG+ WRQ+ +V++G+ GF+ WL HL+ LR PGDDLM Sbjct 186 GVPEQDRKHILHFGELGAPSLDIGLSWRQFQQVEEGLVGFNAWLGDHLEALRRNPGDDLM 245 Query 240 SQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQH 299 S+LI + + D +L E EL+A AGLVL AGFETTVNLLGNGIRMLLDTP+HL TL Sbjct 246 SELILASAAADEAGRLSERELQATAGLVLAAGFETTVNLLGNGIRMLLDTPQHLETLAAR 305 Query 300 PELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPH 359 P+LWPNTVEEILRLDSPVQ++AR A RDVEVAG RI+RGE+V+++LA ANRDP VF DPH Sbjct 306 PDLWPNTVEEILRLDSPVQMSARFARRDVEVAGTRIERGELVIVHLAGANRDPNVFDDPH 365 Query 360 RFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVL 419 RFDIER NAGRHL+FS GRHFCLGAALARAEGEVGLRTFF R+PD + AG+GSRRDTRVL Sbjct 366 RFDIERDNAGRHLSFSGGRHFCLGAALARAEGEVGLRTFFQRYPDAQLAGSGSRRDTRVL 425 Query 420 RGWSTLPVTLGPA 432 RGWSTLP+TLG A Sbjct 426 RGWSTLPITLGKA 438 >gi|108797413|ref|YP_637610.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119866497|ref|YP_936449.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108767832|gb|ABG06554.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119692586|gb|ABL89659.1| cytochrome P450 [Mycobacterium sp. KMS] Length=447 Score = 573 bits (1478), Expect = 1e-161, Method: Compositional matrix adjust. Identities = 288/439 (66%), Positives = 340/439 (78%), Gaps = 6/439 (1%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 V+ ++ WLA+HG +RG++ +G+RRGD QARLIADP V +P F DE R G L+R R Sbjct 10 VRQRVRWLALHGFVRGMSRLGMRRGDPQARLIADPTVRANPAAFADEHRVKGPLIRGRVG 69 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 +T DH +AH+LLRSDDFRV S G LP PLR + RT LHP+ PSLL++EPPDHT Sbjct 70 LITFDHAVAHELLRSDDFRVSSLGGELPKPLRRVIDRTDTGLLHPIEPPSLLSIEPPDHT 129 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLD---RFAEQPGIVDVVGRYCSQLPIVVISE 177 R RK VS+VFT+RAV+ALRD VE TA+ LLD R A G VD+V RYCS LP+ VIS+ Sbjct 130 RCRKLVSSVFTTRAVTALRDGVETTAVKLLDDLERDATGSGPVDIVARYCSLLPVSVISD 189 Query 178 ILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDD 237 +LGVPE DR ++L +GEL APSLDIG+ W+QYLRV GI GF+ WL HL+ LR PGDD Sbjct 190 VLGVPEADRAQILHYGELGAPSLDIGLSWQQYLRVHSGIVGFNAWLVNHLENLRRNPGDD 249 Query 238 LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 L+SQLI E G L E EL+A AGLVL AGFETTVNLLGNGI+MLLD P+ LA LR Sbjct 250 LLSQLISATEDG---AGLSERELQATAGLVLAAGFETTVNLLGNGIKMLLDHPDQLAKLR 306 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 PELWP VEEILRLDSPVQ++ARVA +DVEVAGV ++ GE+++I+LA ANRDP VF D Sbjct 307 DRPELWPTAVEEILRLDSPVQMSARVAKKDVEVAGVPVRAGELIIIHLAGANRDPKVFDD 366 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 PHRFDIER NAG+HL+FS GRHFCLGAALARAEGEVGLRTFFDRFPD + AG SRRDTR Sbjct 367 PHRFDIERDNAGKHLSFSGGRHFCLGAALARAEGEVGLRTFFDRFPDAKLAGTASRRDTR 426 Query 418 VLRGWSTLPVTLGPARSMV 436 VLRGWSTLP+TLG AR+ + Sbjct 427 VLRGWSTLPITLGTARAAL 445 >gi|126433032|ref|YP_001068723.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126232832|gb|ABN96232.1| cytochrome P450 [Mycobacterium sp. JLS] Length=447 Score = 572 bits (1475), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 288/439 (66%), Positives = 340/439 (78%), Gaps = 6/439 (1%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 V+ ++ WLA+HG +RG++ +G+RRGD QARLIADP V +P F DE R G L+R R Sbjct 10 VRQRVRWLALHGFVRGMSRLGMRRGDPQARLIADPTVRANPAAFADEHRVKGPLIRGRVG 69 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 +T DH +AH+LLRSDDFRV S G LP PLR + RT LHP+ PSLL++EPPDHT Sbjct 70 LITFDHAVAHELLRSDDFRVSSLGGELPRPLRRVIDRTDTGLLHPIEPPSLLSIEPPDHT 129 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLD---RFAEQPGIVDVVGRYCSQLPIVVISE 177 R RK VS+VFT+RAV+ALRD VE TA+ LLD R A G VD+V RYCS LP+ VIS+ Sbjct 130 RCRKLVSSVFTTRAVTALRDGVEATAVKLLDDLERDATGSGPVDIVARYCSLLPVSVISD 189 Query 178 ILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDD 237 +LGVPE DR ++L +GEL APSLDIG+ W+QYLRV GI GF+ WL HL+ LR PGDD Sbjct 190 VLGVPEADRAQILHYGELGAPSLDIGLSWQQYLRVHSGIVGFNAWLVNHLENLRRNPGDD 249 Query 238 LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 L+SQLI E G L E EL+A AGLVL AGFETTVNLLGNGI+MLLD P+ LA LR Sbjct 250 LLSQLISATEDG---AGLSERELQATAGLVLAAGFETTVNLLGNGIKMLLDHPDQLAKLR 306 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 PELWP VEEILRLDSPVQ++ARVA +DVEVAGV ++ GE+++I+LA ANRDP VF D Sbjct 307 DRPELWPTAVEEILRLDSPVQMSARVAKKDVEVAGVPVRAGELIIIHLAGANRDPKVFDD 366 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 PHRFDIER NAG+HL+FS GRHFCLGAALARAEGEVGLRTFFDRFPD + AG SRRDTR Sbjct 367 PHRFDIERDNAGKHLSFSGGRHFCLGAALARAEGEVGLRTFFDRFPDAKLAGTASRRDTR 426 Query 418 VLRGWSTLPVTLGPARSMV 436 VLRGWSTLP+TLG AR+ + Sbjct 427 VLRGWSTLPITLGTARAAL 445 >gi|118468531|ref|YP_885089.1| P450 heme-thiolate protein [Mycobacterium smegmatis str. MC2 155] gi|118169818|gb|ABK70714.1| P450 heme-thiolate protein [Mycobacterium smegmatis str. MC2 155] Length=422 Score = 556 bits (1434), Expect = 2e-156, Method: Compositional matrix adjust. Identities = 275/421 (66%), Positives = 324/421 (77%), Gaps = 0/421 (0%) Query 17 IAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLAHDLLRSD 76 +A +G+RRGD QARLIADP V DP F D++R G ++R R LT DH +A DLLRSD Sbjct 1 MATLGLRRGDPQARLIADPVVRADPTTFADQMRKQGPVIRGRVVLLTFDHAVAFDLLRSD 60 Query 77 DFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVS 136 DF+V G NLP PLRW+ +T LHP+ PSLL++EPPDHTR RK VS+VFT+RAV+ Sbjct 61 DFQVSQLGANLPKPLRWIADKTNPGLLHPIEPPSLLSIEPPDHTRMRKLVSSVFTTRAVA 120 Query 137 ALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELA 196 LR+ VEQTA LLD + G+VD+V RYC+QLP+ VI +ILGVPE DRP +L +GEL Sbjct 121 TLRERVEQTAHELLDGLEAESGVVDIVERYCAQLPVAVIGDILGVPEPDRPNILRYGELG 180 Query 197 APSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESGDNETQLD 256 APSLDIG+ W QY +V +GI GF+ WL HL+ LR PGDDL+SQ+I +ESG L Sbjct 181 APSLDIGLSWSQYQQVNEGIIGFETWLNRHLRTLRRDPGDDLLSQIITASESGATGEPLT 240 Query 257 ETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEEILRLDSP 316 + EL+A+AGLVL AGFETTVNLLGNGIRMLLD EHL TL P++WPN VEEILRLDSP Sbjct 241 DRELKALAGLVLAAGFETTVNLLGNGIRMLLDHREHLETLAARPDVWPNAVEEILRLDSP 300 Query 317 VQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAGRHLAFST 376 VQ+TAR A RDV+VAG + RGE+VV+++A ANRDP VF DPHRFDIER NAGRHL+FS Sbjct 301 VQMTARAAVRDVDVAGTAVGRGELVVLHIAGANRDPKVFDDPHRFDIERDNAGRHLSFSG 360 Query 377 GRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTLGPARSMV 436 GRHFCLGAALARAEGEVGLR FFDRFPD R AG RRDTRVLRGWSTLP+ LG AR+ V Sbjct 361 GRHFCLGAALARAEGEVGLRAFFDRFPDARLAGDPVRRDTRVLRGWSTLPIALGKARAAV 420 Query 437 S 437 Sbjct 421 G 421 >gi|49146137|ref|YP_025575.1| cytochrome p450 150 cyp150 [Mycobacterium ulcerans Agy99] gi|42414771|emb|CAE46864.1| probable cytochrome p450 150 cyp150 [Mycobacterium ulcerans Agy99] Length=437 Score = 546 bits (1408), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 272/435 (63%), Positives = 333/435 (77%), Gaps = 1/435 (0%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 ++ +L+W+A HG++RG A + R GD+Q+RL+ADP V +P PF DE+R+ G +V + Sbjct 1 MRQRLNWIAAHGLLRGTARLAARLGDVQSRLVADPMVMANPAPFCDELRAIGPVVSSYGT 60 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHT 120 +L V H +AH+LLRS+DF VVS G NLP P+RWLERRTR D H L PSLLAVEPP+HT Sbjct 61 HLVVSHAIAHELLRSEDFEVVSLGSNLPAPMRWLERRTRDDTPHLLLPPSLLAVEPPNHT 120 Query 121 RYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILG 180 RYRK VS+VFT +AV+ LRD VE+TA LLD+ +Q VD++ RYCSQLP+ VI +ILG Sbjct 121 RYRKAVSSVFTPKAVAGLRDHVEETASALLDQLTDQASAVDIIARYCSQLPVAVICDILG 180 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VP DR RVL+FG+LA P LD G+ WRQ+ +V+QG++G W+ HL++LR PGDDLMS Sbjct 181 VPSRDRNRVLKFGQLAGPCLDFGLTWRQHQQVRQGLQGLHFWITEHLEELRSNPGDDLMS 240 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 Q+I +E+G +ET L TE+R I GLVL A F TT++LLGNGI++LLD PE L Q P Sbjct 241 QMIHASENGSSETHLHATEVRMI-GLVLGASFATTMDLLGNGIQVLLDAPELRDALSQRP 299 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 +LWPN VEEILRL+ PVQL R+A +D EVAG IKRG++V IYL A NRDP+VF DPHR Sbjct 300 QLWPNAVEEILRLEPPVQLAGRMARKDTEVAGTAIKRGQLVAIYLGAVNRDPSVFADPHR 359 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FDI R NA RHLAFS GRHFCLGAALAR EGEVGLR F+RFPDVRAAG G+RRDTR LR Sbjct 360 FDITRANANRHLAFSGGRHFCLGAALARVEGEVGLRMLFERFPDVRAAGPGNRRDTRTLR 419 Query 421 GWSTLPVTLGPARSM 435 GWS LPV LG ARSM Sbjct 420 GWSQLPVQLGAARSM 434 >gi|300785252|ref|YP_003765543.1| cytochrome P450 [Amycolatopsis mediterranei U32] gi|299794766|gb|ADJ45141.1| cytochrome P450 [Amycolatopsis mediterranei U32] gi|340526695|gb|AEK41900.1| cytochrome P450 [Amycolatopsis mediterranei S699] Length=434 Score = 396 bits (1018), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 216/431 (51%), Positives = 269/431 (63%), Gaps = 7/431 (1%) Query 2 KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANY 61 K + W H + R + RRGDLQ R++ A +D ++E+R G L R R + Sbjct 10 KPVVRWGLGHALPRTVLRREARRGDLQGRMVVAAADGSDLTGLFEEIRETGPLARTRFGW 69 Query 62 LTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTR 121 +T H ++L +DFRV G + R +E + G+ LHP+R PSLLAV PP+HTR Sbjct 70 MTTTHATVREVLAGEDFRVGVIGSDGSALGRLVEW-SAGEHLHPVRPPSLLAVNPPEHTR 128 Query 122 YRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGI-VDVVGRYCSQLPIVVISEILG 180 YRK V+ VFT RAV LR V++ A LLD PG +D+V YC LP+ VISEILG Sbjct 129 YRKLVTGVFTVRAVEQLRGRVQEIADGLLDTL--DPGAPLDLVESYCGLLPVTVISEILG 186 Query 181 VPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMS 240 VP D +VL G AAPSLD+G+ WR + V+ + FD WL HL LR PG+DL S Sbjct 187 VPPSDLGKVLSLGAAAAPSLDLGLGWRTFRHVETALAEFDTWLGEHLGHLRRNPGNDLFS 246 Query 241 QLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHP 300 +L+ + G L ETEL++ AGLVL AGFETTVNLLG+GI +L P LA LR+ P Sbjct 247 KLVAARDGG---VGLTETELKSTAGLVLAAGFETTVNLLGSGIALLAGDPGQLAVLRERP 303 Query 301 ELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHR 360 ELW N VEE+LR D PV LT R+A R EVAGV + RG +V LA ANRDP VF DP Sbjct 304 ELWGNAVEEVLRYDPPVLLTGRLATRATEVAGVPLPRGALVTTVLAGANRDPGVFADPAV 363 Query 361 FDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLR 420 FD+ R A H++F GRH CLGA+LAR EGE+GLRT FDRFP +R G RR TR+LR Sbjct 364 FDVARAGARDHVSFGAGRHHCLGASLARMEGEIGLRTIFDRFPGLRVLPGGRRRSTRILR 423 Query 421 GWSTLPVTLGP 431 G+ TLP L P Sbjct 424 GYETLPAVLAP 434 >gi|326328979|ref|ZP_08195309.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] gi|325953238|gb|EGD45248.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] Length=456 Score = 381 bits (979), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 215/435 (50%), Positives = 272/435 (63%), Gaps = 13/435 (2%) Query 2 KDKLHWLAMHGVIRGIAAIGIRRGDLQARLI-ADPAVAT-DPVPFYDEVRSHGALVRNRA 59 K + W HG+ R + ++GDLQ LI + P T D + ++EVR+ G L R Sbjct 27 KQGVRWALGHGLPRTVITRAAKKGDLQGDLILSGPGSHTFDLIDLFEEVRAQGPLYRGAF 86 Query 60 NYLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERR---TRGDQLHPLREPSLLAVEP 116 + + D + ++L S DF F + W+ + D +P++ PSLLA EP Sbjct 87 SQVATDQAVIREVLTSSDFVTGFFAPDAGGG--WMAKAGTWAASDVFNPIQPPSLLATEP 144 Query 117 PDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGI--VDVVGRYCSQLPIVV 174 P HTRYRK V+ VFT +AV LR E+ A LLD E+ G VD+V RYC LPI V Sbjct 145 PAHTRYRKLVTRVFTVKAVERLRGRTEEIARELLDDL-EKSGASEVDLVSRYCGLLPITV 203 Query 175 ISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAP 234 ISE+LGVP R R+LE G+ AA SLDIG+ W + ++ + FD WL GHL + P Sbjct 204 ISEVLGVPVELRERMLEMGKGAALSLDIGLDWGTFRGMEASLEEFDTWLRGHLDHIAAHP 263 Query 235 GDDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLA 294 GDDL+SQL+ + E GD +L E ELRAIAGLV AGFETTVNL+GNGI +L D PE L Sbjct 264 GDDLLSQLVAVREDGD---RLSEHELRAIAGLVFAAGFETTVNLIGNGIALLHDNPEQLD 320 Query 295 TLRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAV 354 LR PELW N +E+LRLD PV LT RVA +D +AG I RG ++ LAAANRDPAV Sbjct 321 ILRDRPELWANAADEVLRLDPPVLLTGRVARQDSVIAGQPIPRGTIINTILAAANRDPAV 380 Query 355 FPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRR 414 F DPH FD+ R NA H++FS+GRHFCLGAALAR EGE+GLR F+RFPD++ R Sbjct 381 FTDPHVFDVTRENARDHISFSSGRHFCLGAALARMEGEIGLRLLFERFPDLKLLDGRERH 440 Query 415 DTRVLRGWSTLPVTL 429 TR+LRG+S LP L Sbjct 441 PTRILRGYSRLPARL 455 >gi|331695871|ref|YP_004332110.1| Linalool 8-monooxygenase [Pseudonocardia dioxanivorans CB1190] gi|326950560|gb|AEA24257.1| Linalool 8-monooxygenase [Pseudonocardia dioxanivorans CB1190] Length=441 Score = 375 bits (962), Expect = 9e-102, Method: Compositional matrix adjust. Identities = 208/427 (49%), Positives = 273/427 (64%), Gaps = 5/427 (1%) Query 5 LHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTV 64 + W HGV+R R G+L ARL+ DP V +P PFY+E+R+ G V + Sbjct 11 IRWGLRHGVVRRAVGKRARAGELGARLMLDPEVLAEPYPFYEELRARGRFVDTGLALTSA 70 Query 65 DHRLAHDLLRSDDFRV-VSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYR 123 H +A ++LRS DF V + ENLP P+R R L P++ PS+LA +PPDHTRYR Sbjct 71 HHDVATEVLRSKDFGVGMRMPENLPGPVRLAVRAGGRWALGPVQPPSMLAADPPDHTRYR 130 Query 124 KTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPG-IVDVVGRYCSQLPIVVISEILGVP 182 K V+ F++RAV+ALR E+ A LLD A +PG D+V Y + LP VI+E+LG P Sbjct 131 KLVTRAFSARAVAALRRRTEEIAAGLLDDLAARPGGTADLVADYAALLPATVIAEMLGAP 190 Query 183 EHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQL 242 R + L +GE A SLD+G+ ++ R ++ I W+ GH ++R PG+D++S L Sbjct 191 LDMRDQFLRWGEGGALSLDMGLTLAEFRRTERDIDALHAWMLGHFDRIRANPGEDILSAL 250 Query 243 IQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPEL 302 + + D E L E EL +IA L+L AGFETTVNL+G+G +L+ P+ LA LR P L Sbjct 251 VGVH---DEEGGLTEDELSSIAMLLLAAGFETTVNLIGSGSALLMQHPDQLALLRDDPSL 307 Query 303 WPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFD 362 WPN V+E+LR+DSPVQ T R+A EV G I+ G VVV+ L ANRDPAVF DP RFD Sbjct 308 WPNAVDEMLRIDSPVQRTGRMAHATTEVLGTTIRAGTVVVVQLGGANRDPAVFDDPTRFD 367 Query 363 IERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGW 422 + R NAG H+AFS+G H+CLGA LAR EGEV LR F+RFPD+ AG G RR TR LRGW Sbjct 368 VTRANAGDHIAFSSGIHYCLGAGLARMEGEVALRALFERFPDLAPAGPGRRRPTRTLRGW 427 Query 423 STLPVTL 429 ++LPV L Sbjct 428 ASLPVAL 434 >gi|284990983|ref|YP_003409537.1| cytochrome P450 [Geodermatophilus obscurus DSM 43160] gi|284064228|gb|ADB75166.1| cytochrome P450 [Geodermatophilus obscurus DSM 43160] Length=464 Score = 363 bits (932), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 207/442 (47%), Positives = 274/442 (62%), Gaps = 11/442 (2%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 V+ + W A HG +R R G+ A+++ DPA+ DP Y+ +R+ L Sbjct 5 VRSAVRWAATHGAMRVAIRARARAGNPDAQVMTDPALRADPYAHYERLRTAAPLADGALG 64 Query 61 YLTVDHRLAHDLLRSDDFRVVSF--GENLPPPLRWLERRTRGDQ--LHPLREPSLLAVEP 116 ++V H + D+LRS+DF + + LPP LR L R G + + P+ PS++AV+P Sbjct 65 RVSVHHDVCTDVLRSEDFGQIGAYRTDRLPPVLR-LALRLAGPRPSVSPIDPPSMVAVDP 123 Query 117 PDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRF----AEQPGIVDVVGRYCSQLPI 172 P+HTRYR+ VS F++RAV+ LR+ Q A LLD A Q G VD+ RY S LP+ Sbjct 124 PEHTRYRRLVSRAFSARAVAGLRERTRQIADELLDELEGEAAAQDGQVDLAARYASLLPV 183 Query 173 VVISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRH 232 VISE+LGVP R + L +G+ AAP LD+G+ W + V++ + D W GHLQQLR Sbjct 184 TVISEMLGVPVAMREQFLAWGDRAAPVLDMGLDWSTHRDVERSLGELDSWWRGHLQQLRR 243 Query 233 APGDDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEH 292 PG DL+S L+ + D+ L ETELRA A LV+ AGFETTVNL+GNG +L P+ Sbjct 244 DPGADLLSALVTTVD--DDGGGLTETELRATAALVVGAGFETTVNLIGNGAALLFAHPDQ 301 Query 293 LATLRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDP 352 L + P LWPN V+E+LR+D PVQ T R A R V GV + GE +++ LAAA+RDP Sbjct 302 RRLLAEDPSLWPNAVDEVLRVDPPVQRTGRRARRSTTVHGVPVAEGEWLILLLAAADRDP 361 Query 353 AVFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGS 412 VF DPH FD+ RPNA HLAF +G HFCLGAALAR EGEV L+ F+RFP + AG G Sbjct 362 RVFSDPHVFDVTRPNARDHLAFGSGIHFCLGAALARMEGEVALQALFERFPGLGPAGPGR 421 Query 413 RRDTRVLRGWSTLPVTLGPARS 434 RR T +LRG +LPV LG + S Sbjct 422 RRGTVILRGHESLPVVLGSSTS 443 >gi|324997266|ref|ZP_08118378.1| cytochrome P450 [Pseudonocardia sp. P1] Length=433 Score = 360 bits (924), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 199/427 (47%), Positives = 267/427 (63%), Gaps = 6/427 (1%) Query 11 HGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLAH 70 HG +R +GDL AR+I P DP P Y+E+R+ G +VR+ ++ TVDH + Sbjct 4 HGAVRREVTRQSDKGDLGARMIVHPDAVRDPYPAYEEIRAQGRMVRSALSWTTVDHEITT 63 Query 71 DLLRSDDFRV-VSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAV 129 +LRS DF V + EN P L+ L L P PSLL+++PPDH R RK V+ Sbjct 64 AVLRSPDFCVGMRMPENAPGLLKALMSAGGTWPLGPAEPPSLLSIDPPDHNRIRKLVTRS 123 Query 130 FTSRAVSALRDLVEQTAINLLDRFAEQPGI---VDVVGRYCSQLPIVVISEILGVPEHDR 186 F+++A++ LR E+ A +LLD + G DV+ Y S LP VI+E+LG P R Sbjct 124 FSAKAIARLRTRTEEVAADLLDEMEARTGADRRADVIAEYASLLPATVIAEMLGAPVEMR 183 Query 187 PRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIA 246 + L++GE A SLD+G+ + + R ++ I W+ GH LR P D ++S L+ Sbjct 184 EQFLQWGEGGAYSLDMGLSYAMFRRSEKDIDALAEWMSGHFDHLRAHPNDSILSSLVHAY 243 Query 247 ESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNT 306 +S E +L EL ++A L+L AGFETTVNL+GNG ++LL P+ L P LWPN Sbjct 244 DS--EEGRLTSDELLSLALLLLAAGFETTVNLIGNGTKLLLAHPDQRERLAADPSLWPNA 301 Query 307 VEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERP 366 V+EILRLDSPVQ T RVA RD EV G ++RG +V+ +L ANRDP VFP+P RFD+ R Sbjct 302 VDEILRLDSPVQRTGRVAARDTEVCGFPVRRGALVLTHLGGANRDPEVFPEPDRFDVGRV 361 Query 367 NAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLP 426 A +H+AFS G H+CLGAALA+ EGEVGLR FDR+PD+R+AG R TRVLRG+ +LP Sbjct 362 GADKHVAFSQGIHYCLGAALAKMEGEVGLRALFDRYPDLRSAGPAELRGTRVLRGYRSLP 421 Query 427 VTLGPAR 433 V LG AR Sbjct 422 VRLGDAR 428 >gi|41408131|ref|NP_960967.1| hypothetical protein MAP2033 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396486|gb|AAS04350.1| hypothetical protein MAP_2033 [Mycobacterium avium subsp. paratuberculosis K-10] Length=437 Score = 349 bits (895), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 194/429 (46%), Positives = 260/429 (61%), Gaps = 8/429 (1%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W+AMHG+ R A+ RRGD ARL+ D +++R+ G L+R + +VDH Sbjct 9 WMAMHGLPRAYFAVQARRGDPLARLLRSGTTGEDRYALMEQIRARGPLMRAPFVWASVDH 68 Query 67 RLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKT 125 L +LR F V S E LP P+R L RT +P+ P+++ V+PPDHTRYR+ Sbjct 69 ALCRQVLRDKRFGVTSPTEMELPRPVRALIARTDPGVANPVEPPAMVIVDPPDHTRYRQL 128 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 V+ FT RA+ AL V Q + L++R A P D++ + ++LP+ +I+EILG+P Sbjct 129 VAQSFTPRAIEALNTRVAQVTLELIERIATIPQ-PDLIADFATRLPVAIIAEILGMPPDS 187 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 PR+L +G +P LD+GI WR Y G+RG D +L H QLR P D + ++ Sbjct 188 YPRMLAWGRSGSPLLDLGIDWRTYRDAIDGLRGVDEYLLAHFHQLRADPHSD--NPFGRM 245 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 A G L + EL A A L++ AGFETTVNL+GNGI +LL PE LA L +P+LWP+ Sbjct 246 AADG----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLRHPEQLALLHDNPDLWPS 301 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEEILR+ SPVQ+TAR DV++AG I GE+V ++L ANRDP VF DP FD+ R Sbjct 302 AVEEILRIASPVQMTARTPACDVDIAGAHIGAGEMVGLFLGGANRDPKVFSDPTTFDVTR 361 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 PNA HLAF++G H CLGAALAR EG LR F+ FPD+R A RR L G++ L Sbjct 362 PNAREHLAFASGIHACLGAALARIEGATALRALFENFPDLRLTAAPQRRSLINLHGYTRL 421 Query 426 PVTLGPARS 434 P LG R+ Sbjct 422 PAQLGGRRT 430 >gi|336461806|gb|EGO40664.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=437 Score = 349 bits (895), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 194/429 (46%), Positives = 260/429 (61%), Gaps = 8/429 (1%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W+AMHG+ R A+ RRGD ARL+ D +++R+ G L+R + +VDH Sbjct 9 WMAMHGLPRAYFAVQARRGDPLARLLRSGTTGEDRYALMEQIRARGPLMRAPFVWASVDH 68 Query 67 RLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKT 125 L +LR F V S E LP P+R L RT +P+ P+++ V+PPDHTRYR+ Sbjct 69 ALCRQVLRDKRFGVTSPTEMELPRPVRALIARTDPGVANPVEPPAMVIVDPPDHTRYRQL 128 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 V+ FT RA+ AL V Q + L++R A P D++ + ++LP+ +I+EILG+P Sbjct 129 VAQSFTPRAIEALNTRVAQVTMELIERIATIPQ-PDLIADFATRLPVAIIAEILGMPPDS 187 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 PR+L +G +P LD+GI WR Y G+RG D +L H QLR P D + ++ Sbjct 188 YPRMLAWGRSGSPLLDLGIDWRTYRDAIDGLRGVDEYLLAHFHQLRADPHSD--NPFGRM 245 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 A G L + EL A A L++ AGFETTVNL+GNGI +LL PE LA L +P+LWP+ Sbjct 246 AADG----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLRHPEQLALLHDNPDLWPS 301 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEEILR+ SPVQ+TAR DV++AG I GE+V ++L ANRDP VF DP FD+ R Sbjct 302 AVEEILRIASPVQMTARTPACDVDIAGAHIGAGEMVGLFLGGANRDPKVFSDPTTFDVTR 361 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 PNA HLAF++G H CLGAALAR EG LR F+ FPD+R A RR L G++ L Sbjct 362 PNAREHLAFASGIHACLGAALARIEGATALRALFENFPDLRLTAAPQRRSLINLHGYTRL 421 Query 426 PVTLGPARS 434 P LG R+ Sbjct 422 PAQLGGRRT 430 >gi|254774866|ref|ZP_05216382.1| P450 heme-thiolate protein [Mycobacterium avium subsp. avium ATCC 25291] Length=437 Score = 348 bits (892), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 191/429 (45%), Positives = 260/429 (61%), Gaps = 8/429 (1%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W+AMHG+ R A+ RRGD ARL+ D +++R+ G L+R + +VDH Sbjct 9 WMAMHGLPRAYFAVQARRGDPLARLLRSGTTGEDRYALMEQIRARGPLMRAPFVWASVDH 68 Query 67 RLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKT 125 + +LR F V S E LP P+R L +T +P+ P+++ V+PPDHTRYR+ Sbjct 69 AVCRQVLRDKRFGVTSPTEMELPRPVRALIAKTDPGVANPVEPPAMVIVDPPDHTRYRQL 128 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 V+ FT RA+ AL V Q + L++R A P D++ + ++LP+ +I+EILG+P Sbjct 129 VAQSFTPRAIEALNTRVAQVTMELIERIAATPQ-PDLIADFATRLPVAIIAEILGMPPDS 187 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 PR+L +G +P LD+GI W+ Y G+RG D +L H QLR P D + ++ Sbjct 188 YPRMLAWGRSGSPLLDLGIDWKTYRDAIDGLRGVDEYLLAHFHQLRADPHSD--NPFGRM 245 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 A G L + EL A A L++ AGFETTVNL+GNGI +LL PE LA L +P+LWP+ Sbjct 246 AADG----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLQHPEQLALLHDNPDLWPS 301 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEEILR+ SPVQ+TAR DV++AG I GE+V ++L ANRDP VF DP FD+ R Sbjct 302 AVEEILRIASPVQMTARTPSCDVDIAGAHIGAGEMVGLFLGGANRDPKVFSDPTTFDVTR 361 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 PNA HLAF++G H CLGAALAR EG LR F+ FPD+R A RR L G++ L Sbjct 362 PNAREHLAFASGIHACLGAALARIEGATALRALFENFPDLRLTAAPQRRSLINLHGYTRL 421 Query 426 PVTLGPARS 434 P LG R+ Sbjct 422 PAQLGGRRT 430 >gi|309812503|ref|ZP_07706256.1| putative cytochrome P450 107B1 [Dermacoccus sp. Ellin185] gi|308433558|gb|EFP57437.1| putative cytochrome P450 107B1 [Dermacoccus sp. Ellin185] Length=448 Score = 348 bits (892), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 206/437 (48%), Positives = 255/437 (59%), Gaps = 16/437 (3%) Query 2 KDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPA--VATDPVPFYDEVRSHGALVRNRA 59 K + W H + R +GD Q L + + + P +R+ GA+V + Sbjct 17 KPGVRWSLQHAIPRRALVRVASQGDPQGVLSTETTGLLPEELEPILARIRNGGAIVTGKL 76 Query 60 NYLTVDHRLAHDLLRSDDFRVVSFGEN---LPPPLRWLERRTRGDQLHPLREPSLLAVEP 116 + LT +H +++L S+DFR G+ + L W T G PL PSLLA + Sbjct 77 STLTGEHDAVNEVLTSNDFRTGFPGDTSRAVRGALTWAASTTIG----PLEPPSLLATDG 132 Query 117 PDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRF---AEQPGIVDVVGRYCSQLPIV 173 P HTR RK V+ VFT+RAV ALR+ EQ A LLD A VD+V RYC QLP+ Sbjct 133 PTHTRNRKLVTRVFTARAVEALRERTEQVATELLDDLEADARAGHDVDLVARYCEQLPVT 192 Query 174 VISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHA 233 VI+EILGVPE + VL G AA SLD+G+ W + R + + FD WLE HL R Sbjct 193 VIAEILGVPESEYETVLRLGGHAASSLDLGLDWATFRRTESALDEFDAWLETHLAAKRAQ 252 Query 234 PGDDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHL 293 PGD S LIQ + D+ L + EL+++AGLVL AGFETTVNLLGN IR+++ PE L Sbjct 253 PGDGPFSALIQ---AQDDGVGLSDQELKSVAGLVLAAGFETTVNLLGNAIRLIVGHPEQL 309 Query 294 ATLRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPA 353 A LR W N VEE LR D PV LTAR A D VA V + G +VV LAAANRDP Sbjct 310 AALRSGEASWLNAVEETLRFDPPVLLTARTATCDTRVADVDVAAGTLVVTVLAAANRDPK 369 Query 354 VFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSR 413 +F DP FD+ R NA HLAFS GRHFCLGAAL+R E EV LR FFDRF DV +R Sbjct 370 IFDDPDAFDVHRENAREHLAFSAGRHFCLGAALSRMESEVALRAFFDRF-DVELLPGATR 428 Query 414 RDTRVLRGWSTLPVTLG 430 R TR+LRG++TLP L Sbjct 429 RPTRILRGYATLPARLA 445 >gi|118463470|ref|YP_881366.1| P450 heme-thiolate protein [Mycobacterium avium 104] gi|118164757|gb|ABK65654.1| P450 heme-thiolate protein [Mycobacterium avium 104] Length=437 Score = 347 bits (891), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 192/429 (45%), Positives = 260/429 (61%), Gaps = 8/429 (1%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W+AMHG+ R A+ RRGD ARL+ D +++R+ G L+R + +VDH Sbjct 9 WMAMHGLPRAYFAVQARRGDPLARLLRSGTTGEDRYALMEQIRARGPLMRAPFVWASVDH 68 Query 67 RLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKT 125 + +LR F V S E LP P+R L RT +P+ P+++ V+PPDHTRYR+ Sbjct 69 AVCRQVLRDKRFGVTSPTEMELPRPVRALIARTDPGVANPVAPPAMVIVDPPDHTRYRQL 128 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 V+ FT RA+ AL V Q + L++R A P D++ + ++LP+ +I+EILG+P Sbjct 129 VAQSFTPRAIEALNTRVAQVTMELIERIAATPQ-PDLIADFATRLPVAIIAEILGMPPDS 187 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 PR+L +G +P LD+GI W+ Y G+RG D +L H QLR P D + ++ Sbjct 188 YPRMLAWGRSGSPLLDLGIDWKTYRDAIAGLRGVDEYLLAHFHQLRADPHSD--NPFGRM 245 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 A G L + EL A A L++ AGFETTVNL+GNGI +LL PE LA L +P+LWP+ Sbjct 246 AADG----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLRHPEQLALLHDNPDLWPS 301 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEEILR+ SPVQ+TAR DV++AG I GE+V ++L ANRDP VF DP FD+ R Sbjct 302 AVEEILRIASPVQMTARTPACDVDIAGAHIGAGEMVGLFLGGANRDPKVFSDPTTFDVTR 361 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 PNA HLAF++G H CLGAALAR EG LR F+ FPD+R A RR L G++ L Sbjct 362 PNAREHLAFASGIHACLGAALARIEGATALRALFENFPDLRLTAAPQRRSLINLHGYTRL 421 Query 426 PVTLGPARS 434 P LG R+ Sbjct 422 PAQLGGRRT 430 >gi|326329287|ref|ZP_08195612.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] gi|325952862|gb|EGD44877.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] Length=429 Score = 343 bits (879), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 190/424 (45%), Positives = 258/424 (61%), Gaps = 13/424 (3%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W G+ R + ++ RRGD A L+ + VP YD +R+ G + N TV + Sbjct 18 WALSQGINRAVLSLASRRGDPLAELMW-----SRDVPDYDRLRARGPIHVNPFMAGTVSY 72 Query 67 RLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRG-DQLHPLREPSLLAVEPPDHTRYRKT 125 A+++LRS DF V LP PLRWL + D L P+ PS+LAV+PP HTRYRK Sbjct 73 AAANEILRSSDFGVGDGQGELPVPLRWLLGKVSAPDALGPVDPPSMLAVDPPLHTRYRKH 132 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 VS FT+R +S++ ++V A +LLD + G VD++ Y ++LPI VI+E+LGVP+ D Sbjct 133 VSKAFTARRISSMAEMVTAVAGDLLDEIDPREGRVDIIEEYAAKLPIAVIAELLGVPDSD 192 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 R +L +G+ AA LD G+ WR Y +V+ +R W E H+++LR P DDL+S L+ Sbjct 193 RADILRWGDQAAAILDPGLSWRDYAQVETAMRSLHHWFEDHVRRLRTDPADDLLSALVI- 251 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 +GD LD+ EL A+ LVL AGFETTVNLLGN + L PE + P L Sbjct 252 --AGD----LDDIELHALGLLVLAAGFETTVNLLGNAVAALDAHPEQRSLFLVEPTLADG 305 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEE LR D PV T R A D VAG+ + +G V + + ANRDP+VF +P +DI R Sbjct 306 VVEETLRWDPPVMATVRQAYADTRVAGMDVAKGTAVAVVIGGANRDPSVFENPDTYDITR 365 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 P+A +HL+FS G HFCLGA+LAR E VGLR F+R+P +R G RR TR+LRG+++L Sbjct 366 PDADQHLSFSAGAHFCLGASLARLEARVGLRLLFERYPSLRVTGEAVRRPTRILRGYASL 425 Query 426 PVTL 429 PV L Sbjct 426 PVAL 429 >gi|54026614|ref|YP_120856.1| cytochrome P450 monooxygenase [Nocardia farcinica IFM 10152] gi|54018122|dbj|BAD59492.1| cytochrome P450 monooxygenase [Nocardia farcinica IFM 10152] Length=436 Score = 338 bits (868), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 194/427 (46%), Positives = 252/427 (60%), Gaps = 10/427 (2%) Query 5 LHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTV 64 WL+ G R + RRGD ARL+ DP P +++R G VR ++ Sbjct 7 FRWLSAQGAPRLVLRTQARRGDPFARLVGGREGIEDPYPLIEQLRGDGGPVRTPLSWAAF 66 Query 65 DHRLAHDLLRSDDFRVVSFGENLP-PPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYR 123 DH L +LR + F V S PL+ L R+ S+L ++PP+HT R Sbjct 67 DHELCRAILRDNRFGVRSPQSFTAFEPLKRLAARSPLPPNPVEPP-SMLVIDPPEHTAMR 125 Query 124 KTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPE 183 K V+A FT RA+ LRD V LLD G VD+V Y SQ+PI +ISE+LG P+ Sbjct 126 KPVAAAFTPRAIGRLRDRVASVTTELLDALPSH-GSVDLVAAYASQVPIAIISEMLGFPD 184 Query 184 HDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLI 243 DR L +G+ P LDIGIPWR + R + + +L+ H+ +LR PGDD++S L+ Sbjct 185 ADRQMFLGWGDRMTPLLDIGIPWRAHKRALLAMEVMNDYLDRHIARLRREPGDDILSALV 244 Query 244 QIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELW 303 +GD LD+ L+A A L++ AGFETTVNL+GNG+ LL P+ LA LR+ P+LW Sbjct 245 T---AGD----LDDHALKASASLLMGAGFETTVNLIGNGVVQLLAHPDQLARLREEPDLW 297 Query 304 PNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDI 363 PN VEEILR+DSPVQ TAR A DVE+ G ++RG VV+ LA ANRDP VF DP RFD+ Sbjct 298 PNAVEEILRIDSPVQSTARTALTDVELDGALLRRGHTVVLSLAGANRDPKVFADPERFDV 357 Query 364 ERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWS 423 RPNA HL+FS+G H CLGA+LAR EG LR F+RFPD+ A RR L G+ Sbjct 358 ARPNAKDHLSFSSGIHVCLGASLARMEGVYALRALFERFPDLAPAEPPHRRALFTLHGYE 417 Query 424 TLPVTLG 430 +PV LG Sbjct 418 RMPVHLG 424 >gi|157885004|gb|ABV91294.1| probable cytochrome P450 [Streptomyces griseochromogenes] Length=449 Score = 333 bits (854), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 198/434 (46%), Positives = 255/434 (59%), Gaps = 10/434 (2%) Query 3 DKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYL 62 D W HG+IR +G+ + DP+V +P Y+ +RS V + + Sbjct 17 DSARWALTHGLIRLAMRREAAKGNPATLRVTDPSVRLNPYAHYETMRSDQPFVGGLGSKM 76 Query 63 TVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRY 122 TV H +A ++LRSD +FG P R L PS++AV+PP HTRY Sbjct 77 TVRHDVASEVLRSDAMGAAAFGGAPAPIRRILAAFAPSAARSVFEPPSMVAVDPPYHTRY 136 Query 123 RKTVSAVFTSRAVSALRDLVEQTAINLLDRFA----EQPGIVDVVGRYCSQLPIVVISEI 178 RK V F+++AV+ALR E+ A LLD A +P VD+V Y SQLP VVI E+ Sbjct 137 RKLVVRAFSAKAVNALRVRTEEVAATLLDAIAARDLREP--VDLVQAYTSQLPSVVICEM 194 Query 179 LGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDL 238 LG P + L++ + AA LD G+ R++L Q+ I WL GH LRH PG D+ Sbjct 195 LGAPTGMSEQFLQWSDAAASPLDPGMSRRRFLADQRRIDALLDWLRGHFDHLRHHPGQDI 254 Query 239 MSQLIQIAESGDNETQ-LDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 MS L+ S D E + L E EL A LVL AG ETTVNL+ NGI +L P A L Sbjct 255 MSDLVN---STDAEGRRLTEAELLATTMLVLAAGLETTVNLMANGIALLEQHPGQRALLA 311 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 + PELWPN V+E+LR++SPVQ +R A RD E+AGVR+ GE+VV+ L AANRDP VF D Sbjct 312 ERPELWPNAVDEMLRVESPVQRISRRALRDTEIAGVRLAEGEIVVVMLGAANRDPEVFTD 371 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 P FD+ R NAG+HLAFSTG H+CLGAALA+ EGEVG R +DRFPD+ G R+ TR Sbjct 372 PAAFDVTRANAGKHLAFSTGIHYCLGAALAKMEGEVGFRALYDRFPDLTLIDEGERKPTR 431 Query 418 VLRGWSTLPVTLGP 431 LRG++ L T P Sbjct 432 NLRGFNRLMATPAP 445 >gi|254818682|ref|ZP_05223683.1| P450 heme-thiolate protein [Mycobacterium intracellulare ATCC 13950] Length=436 Score = 330 bits (847), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 189/432 (44%), Positives = 256/432 (60%), Gaps = 9/432 (2%) Query 4 KLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLT 63 + W AMHGV R A+ RRGD ARL+ A D +++R+ G +VR+ + + Sbjct 6 RARWAAMHGVPRAYFAVQARRGDPLARLLRS-GTADDRYALMEQIRARGRVVRSPYVWAS 64 Query 64 VDHRLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRY 122 VDH + +LR F V + E LP PL+ L +T +P+ P+++ V PPDHTRY Sbjct 65 VDHAVCRQILRDKRFGVTAPSEMELPRPLKALIAKTDPGVANPVEPPAMVIVNPPDHTRY 124 Query 123 RKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVP 182 R+ V+ FT RA+ +L V + + L++R A P D++ + QLP+ +I+EILG+P Sbjct 125 RQLVAQSFTPRAIDSLDTRVAEVTMELIERIAATPQ-PDLIADFAMQLPVAIIAEILGLP 183 Query 183 EHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQL 242 PR+L +G +P LDIGI W+ Y G+RG D +L HL +LR D + Sbjct 184 RDSYPRMLGWGRSGSPLLDIGIDWKTYRDAIDGLRGADDYLLEHLHRLRAGQKSD--NPF 241 Query 243 IQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPEL 302 ++A G L + EL A A L++ AGFETTVNL+GNGI +LL PE LA L +P+L Sbjct 242 GRMAADG----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLQHPEQLALLHDNPDL 297 Query 303 WPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFD 362 WP+ VEEILR SPVQ+TAR DVE+AG I G++V ++L ANRDP VF DP FD Sbjct 298 WPSAVEEILRFASPVQMTARTPNCDVEIAGAHIASGDMVGLFLGGANRDPKVFTDPTTFD 357 Query 363 IERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGW 422 I R NA HLAF++G H CLGAALAR EG LR F+ FPD+R R L G+ Sbjct 358 ITRANARDHLAFASGIHACLGAALARIEGATALRALFESFPDLRLTAPPQPRGLINLHGY 417 Query 423 STLPVTLGPARS 434 + LP LG R+ Sbjct 418 TRLPAQLGGRRA 429 >gi|342857339|ref|ZP_08713995.1| hypothetical protein MCOL_00635 [Mycobacterium colombiense CECT 3035] gi|342134672|gb|EGT87838.1| hypothetical protein MCOL_00635 [Mycobacterium colombiense CECT 3035] Length=426 Score = 330 bits (845), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 189/426 (45%), Positives = 253/426 (60%), Gaps = 8/426 (1%) Query 10 MHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDHRLA 69 MHGV R A+ RRGD ARL+ + +++R+ G +VR+ + +VDH + Sbjct 1 MHGVPRAYFAVQARRGDPLARLLRSNTSGEERYALMEQIRARGPVVRSPFVWASVDHAVC 60 Query 70 HDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSA 128 +LR F V S E LP PL+ L +T +P+ P+++ V+PPDHTRYR V+ Sbjct 61 RQILRDKRFGVTSPTEMELPGPLKKLIAKTDPGVANPVEPPAMVIVDPPDHTRYRHLVAQ 120 Query 129 VFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPR 188 FT RA+ +L V + + L++R A P D++ + QLP+ +I+EILG+P R Sbjct 121 SFTPRAIESLDTRVVEVTMELIERIATTPQ-PDLIADFAMQLPVAIIAEILGLPPDSYSR 179 Query 189 VLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAES 248 +L +G +P LDIGI WR Y G+RG D +L H LR P D + ++A Sbjct 180 MLGWGRSGSPLLDIGIDWRTYRDSIDGLRGVDDYLLEHFHTLRADPRSD--NPFGRMAAD 237 Query 249 GDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVE 308 G L + EL A A L++ AGFETTVNL+GNGI +LL P+ LA L +P+LWP VE Sbjct 238 G----SLTDRELTANAALIVGAGFETTVNLIGNGIVLLLQHPDQLALLHANPDLWPGAVE 293 Query 309 EILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNA 368 EILRL SPVQ+TAR DVE+AG RI G++V ++L ANRDP +F DP RFDI RPNA Sbjct 294 EILRLASPVQMTARTPTCDVEIAGARIAGGDMVGLFLGGANRDPKIFTDPTRFDITRPNA 353 Query 369 GRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVT 428 HLAF++G H CLGAALAR EG LR F+ FPD+R RR L G+S L Sbjct 354 RDHLAFASGIHACLGAALARIEGATALRALFESFPDLRLTAPPQRRGLINLHGYSRLSAQ 413 Query 429 LGPARS 434 LG R+ Sbjct 414 LGGRRT 419 >gi|333988977|ref|YP_004521591.1| cytochrome P450 [Mycobacterium sp. JDM601] gi|333484945|gb|AEF34337.1| cytochrome P450 140A5 Cyp140A5 [Mycobacterium sp. JDM601] Length=396 Score = 320 bits (821), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 182/394 (47%), Positives = 239/394 (61%), Gaps = 13/394 (3%) Query 40 DPVPFYDEVRSHGALVRNRANYLTVDHRLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRT 98 +P P +++R+ G+L R +T DH L +LR D F V + NLP P+RWL RT Sbjct 5 EPEPLIEQIRAAGSLTRTPFVSVTADHGLCRTILRDDRFGVSNPANMNLPRPVRWLISRT 64 Query 99 RGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRF--AEQ 156 +P PS+L V+PPDHTRYR+ V FT RA+ LR + + +LLDR A Q Sbjct 65 DPRLPNPAEPPSMLMVDPPDHTRYRRAVVRAFTPRAIEKLRTRIVEITDDLLDRLESASQ 124 Query 157 PGIVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGI 216 P D++ + LP +I+EILG+PE RP++L+ G+ AP LDIG+ W+ + Q + Sbjct 125 P---DLIADFAGPLPARIIAEILGIPEEMRPQLLDRGDRGAPLLDIGVSWKIFRHAMQSL 181 Query 217 RGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTV 276 R D H+++LR PGDD+ SQ+I+ GD LD EL A LV+ AGFETTV Sbjct 182 RESDRDFGDHVERLRDQPGDDIFSQVIR---DGD----LDRRELGVTALLVVGAGFETTV 234 Query 277 NLLGNGIRMLLDTPEHLATLRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIK 336 NL+GN I +LL + LA LR+ PELWP VEE+LR DSPVQ+T+R D+E+ G R+ Sbjct 235 NLIGNAIVLLLRHRDQLAMLREDPELWPGAVEEVLRFDSPVQMTSRNPLCDLELDGHRLA 294 Query 337 RGEVVVIYLAAANRDPAVFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLR 396 GE V + L AN DP VF DP RFDI R NA HL+FS+G H CLGA LAR E + LR Sbjct 295 AGETVALLLGGANHDPDVFEDPGRFDITRVNAKDHLSFSSGIHACLGANLARMEAAIALR 354 Query 397 TFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTLG 430 F+RFPD+ AGA R L G+ +P T G Sbjct 355 ALFERFPDLALAGAPVPRGLATLHGFRCIPATTG 388 >gi|296141326|ref|YP_003648569.1| cytochrome P450 [Tsukamurella paurometabola DSM 20162] gi|296029460|gb|ADG80230.1| cytochrome P450 [Tsukamurella paurometabola DSM 20162] Length=431 Score = 317 bits (812), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 183/432 (43%), Positives = 246/432 (57%), Gaps = 12/432 (2%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 + ++ W MHG+ R RGD+ A+++ A +D +R G LVR+ Sbjct 9 LTTRVRWAIMHGLPRYALPRRAARGDVMAQMLLGYAEPGSQYAQFDRLREAGTLVRSEVG 68 Query 61 YLTVDHRLAHDLLRSDDFRVVS---FGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPP 117 T DH ++LR FR V FG P PLR + T +P+ PS+L EPP Sbjct 69 ITTADHHACREILRDKRFRTVQPTDFG--FPGPLRRVLELTELGLPNPVEPPSMLVSEPP 126 Query 118 DHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISE 177 HT YR ++ FT +A+ L D + LLD A + D+V Y ++LP+ +I Sbjct 127 AHTAYRHPIARSFTPKAIEQLTDRARTVSAQLLDAMAAKDS-PDLVIDYAARLPVAMIGR 185 Query 178 ILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDD 237 +LG+PE D +LE+GE AAP LD G+ W Y R + +RG D +L H ++ G D Sbjct 186 LLGLPEADDDYMLEWGEAAAPLLDPGLSWPVYWRAVRALRGLDDYLTAHFARVTAQSGGD 245 Query 238 LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 +A SG +L + EL A L++ AGFETTVNL+GNGI LLD PE LA LR Sbjct 246 --HPFALLAASG----ELTDRELVTNAALLIGAGFETTVNLIGNGIVALLDHPEQLARLR 299 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 P+LWPN VEEILR SPVQ TAR+A D EV G+ ++ G ++ + LA ANRDPAVF D Sbjct 300 AEPDLWPNAVEEILRYSSPVQRTARIAAEDAEVLGMPVRAGTMISLQLAGANRDPAVFAD 359 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 P FD+ RP A +H++F G H C+GAALAR EG V LR F+R+PD+ GAG+ R Sbjct 360 PAVFDVARPEAKKHVSFGFGIHACIGAALARMEGAVALRALFERYPDLALDGAGTPRGLS 419 Query 418 VLRGWSTLPVTL 429 L G+S+LP L Sbjct 420 TLYGYSSLPARL 431 >gi|284993031|ref|YP_003411585.1| cytochrome P450 [Geodermatophilus obscurus DSM 43160] gi|284066276|gb|ADB77214.1| cytochrome P450 [Geodermatophilus obscurus DSM 43160] Length=450 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 185/427 (44%), Positives = 246/427 (58%), Gaps = 8/427 (1%) Query 7 WLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVDH 66 W HG+ RRGDL ARL+ DP + DP ++++R+ G LV + LT H Sbjct 27 WAVRHGMPAAYLTREARRGDLVARLLRDPVLRADPHTVHEQLRARGPLVGSALGLLTTSH 86 Query 67 RLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREP-SLLAVEPPDHTRYRKT 125 +A ++LRSD F V P P RW + EP S+L V+PPDHTRYR+ Sbjct 87 AVAAEVLRSDRFGVGFDRSAAPGPARWALAFGDDPAATGVAEPPSMLVVDPPDHTRYRRL 146 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRF---AEQPGIVDVVGRYCSQLPIVVISEILGVP 182 V FT RA +A +V + A LLD A + VD+V + + LP++VI+++LGVP Sbjct 147 VGRAFTPRATAAAEPMVPRVAGTLLDALEPAAARGEPVDLVAAFAAPLPVLVIADLLGVP 206 Query 183 EHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQL 242 + L +G AA +LD G+P R++L + IR +L GH +LR PG+DL+S+L Sbjct 207 TDRQEDFLRWGAAAAATLDPGLPLRRFLAADRAIRALHDFLAGHFARLRREPGEDLVSRL 266 Query 243 IQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPEL 302 + + +E L + EL A L+L AGFETTVNLLGN + +L + L P Sbjct 267 V----AASDEDALSDRELHATVLLLLGAGFETTVNLLGNAVVLLDAHRDQRNALLADPTG 322 Query 303 WPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFD 362 WPN VEE+LR DSPVQ+T R E+AGV ++ G V + L A NRDP VF DP RFD Sbjct 323 WPNAVEEVLRFDSPVQITGRTVRAGTELAGVPVRPGSRVTMLLGAVNRDPDVFADPGRFD 382 Query 363 IERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGW 422 I R NA HLAFS G H+C+GA LAR E V LR +RFP +R G +RRD + LRG+ Sbjct 383 IGRANARDHLAFSAGTHYCVGAGLARMEAAVALRALTERFPGLRVTGRPARRDLQTLRGF 442 Query 423 STLPVTL 429 LPVTL Sbjct 443 EHLPVTL 449 >gi|120406468|ref|YP_956297.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119959286|gb|ABM16291.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=435 Score = 313 bits (802), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 191/429 (45%), Positives = 245/429 (58%), Gaps = 11/429 (2%) Query 5 LHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTV 64 L W +HGV R + RRG+ ARLI D + +E+R+ G L+R + T Sbjct 9 LRWATVHGVPRAFLTVRARRGEPLARLILGRG---DRLALIEEIRAAGPLMRTPVVWATA 65 Query 65 DHRLAHDLLRSDDFRVVSFGEN-LPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYR 123 D+ + +LR +DF V E LP L L RR +P+ P++L +PP HT YR Sbjct 66 DYDVCRTVLRDNDFGVADPSETGLPDALLGLIRRVDPGLPNPVEPPAMLMTDPPQHTEYR 125 Query 124 KTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPE 183 K VS FT R+++AL + + LLD + VD++ Y +QLP VIS +LGVP+ Sbjct 126 KLVSRSFTPRSIAALDTRIGELTAELLDDLGRRRE-VDLIADYAAQLPAAVISRMLGVPD 184 Query 184 HDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLI 243 DR R+L +GE A LDIGI WR + G+ D L H ++L H G D + Sbjct 185 EDRARILGWGETGAALLDIGIGWRPFRAAIDGLVDVDTHLGAHFRRL-HQNGAD-GTPFS 242 Query 244 QIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELW 303 +A G L EL + A L++ AG ETTVNL+GNGI LLD P+ LA LR P LW Sbjct 243 SLALDG----SLSGRELISNAALLVGAGVETTVNLIGNGIAALLDHPDQLALLRDDPGLW 298 Query 304 PNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDI 363 P+ VEEILR DSPVQ+TAR A RD E+AGV I++G V+V+ L ANRDP VF P FDI Sbjct 299 PSAVEEILRYDSPVQMTARTAHRDTEIAGVGIRKGAVIVMLLGGANRDPKVFDRPQTFDI 358 Query 364 ERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWS 423 R NA HLAF++G H CLGAALAR EG LR F R+PD+ RD L G+ Sbjct 359 TRANARDHLAFASGIHVCLGAALARIEGATALRELFTRYPDLHLTAPAEPRDLVTLHGYR 418 Query 424 TLPVTLGPA 432 LPV LG A Sbjct 419 HLPVRLGRA 427 >gi|169631530|ref|YP_001705179.1| putative cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169243497|emb|CAM64525.1| Putative cytochrome P450 [Mycobacterium abscessus] Length=446 Score = 306 bits (784), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 185/442 (42%), Positives = 253/442 (58%), Gaps = 16/442 (3%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K W MHG+ R +R L A L P A + +E+R+ G++ +RA Sbjct 7 IKYWSRWATMHGISRAALLTQVRTLPLAA-LFLGPDRAEKHYRYIEEIRASGSVTPSRAG 65 Query 61 YLT-VDHRLAHDLLRSDDFRVVSFGENLPPPL------RWLERRTRGDQLHPLREPSLLA 113 L D L ++LR + F + N+P P+ RW+ RT +P+ P++LA Sbjct 66 GLIFTDLALTREILRDNRF-ITMAPTNIPSPILPLAFSRWVFARTEPGLPNPVEPPAMLA 124 Query 114 VEPPDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIV 173 V+PP+HTR+RK VS FT RAVS L D V + LLD E+ D++ Y SQLP+ Sbjct 125 VDPPEHTRFRKLVSKAFTPRAVSKLEDRVREVTTELLDNL-ERHERADLLHDYASQLPVA 183 Query 174 VISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHA 233 +I+E+LGVP D P +LE+G A LDIG+ W Y Q + D + + HL +LR Sbjct 184 IIAEMLGVPRADAPFLLEWGNHGAALLDIGMTWSAYRDATQALIEIDRYFDAHLVRLRGE 243 Query 234 PGDD--LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPE 291 +D + L I GD L++ EL+A L+L AGFETTVNL+GNGI LL P+ Sbjct 244 LAEDPTVDGILASIVRDGD----LNDRELKATMALLLGAGFETTVNLIGNGIAALLRHPQ 299 Query 292 HLATLRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRD 351 LA LR++P+ WPN VEEILR DSPVQ+T RVA + E G + G + ++ L ANRD Sbjct 300 QLAHLRENPDGWPNAVEEILRYDSPVQITGRVATQACEFEGHTLAAGSMAILLLGGANRD 359 Query 352 PAVFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAG 411 PAVF P FD+ R NA H+AF +G H CLGA+LAR EG V L++ F+RFP++ A Sbjct 360 PAVFDQPDVFDVLRANAREHVAFGSGIHVCLGASLARMEGVVALQSLFERFPELALAADP 419 Query 412 SRRDTRVLRGWSTLPVTLGPAR 433 + L G+ +LPV LG AR Sbjct 420 TPGKHVNLHGFGSLPVNLGRAR 441 >gi|296394068|ref|YP_003658952.1| cytochrome P450 [Segniliparus rotundus DSM 44985] gi|296181215|gb|ADG98121.1| cytochrome P450 [Segniliparus rotundus DSM 44985] Length=435 Score = 288 bits (737), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 172/429 (41%), Positives = 238/429 (56%), Gaps = 7/429 (1%) Query 5 LHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTV 64 + W +HG R + RG+ ARL+ + +R G LVR + + Sbjct 7 IRWACLHGSTRAAMRVIGWRGEPLARLVLGRGEGEERYRLLGRLRDQGVLVRKPFVWASG 66 Query 65 DHRLAHDLLRSDDFRVVSFGE-NLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYR 123 DH + +LR + F +PP L L R+T +P+ P+++A+ PP+HT YR Sbjct 67 DHGVCRAVLRDNRFAAADAEVVTIPPLLSALFRKTDPQVPNPVEPPAMVAMNPPEHTHYR 126 Query 124 KTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPE 183 + V+ FT RA+ L D V + LLD F E VD+V + +QLP+ VI+E+LG+ Sbjct 127 RLVAQSFTPRAIDKLNDRVVELVTELLDNF-EDGQSVDLVRSFAAQLPVTVIAEMLGMSA 185 Query 184 HDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLI 243 R +L++G+ AP + +G+ W QY R G+R D H ++R D + Sbjct 186 ESREGMLDWGDAGAPLVGLGVTWPQYRRGIAGLREADRDFRAHFDRIRRGACRD-DTPFT 244 Query 244 QIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELW 303 ++A G QL E A A L++ AGFETTVNL+ +GI +LL P+ LA LR P W Sbjct 245 RLAADG----QLSYREFAANAALLVGAGFETTVNLIAHGIVLLLQHPDQLALLRDDPSAW 300 Query 304 PNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDI 363 P VEEILR +SPVQ+TARVA +V++AG R++ G VVV+ L ANRDP+VFPDP RFD+ Sbjct 301 PGAVEEILRFESPVQMTARVAREEVDIAGRRLRPGHVVVLLLGGANRDPSVFPDPDRFDV 360 Query 364 ERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWS 423 R NA HLAF +G H C+G ALARAEG V LR F+RFP +R L G+ Sbjct 361 TRRNAREHLAFGSGVHACVGGALARAEGAVALRMLFERFPGLRLIAPPEPTKMNNLHGYK 420 Query 424 TLPVTLGPA 432 L LG A Sbjct 421 RLRADLGAA 429 >gi|342859660|ref|ZP_08716313.1| putative cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342132792|gb|EGT86012.1| putative cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=434 Score = 279 bits (713), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 163/436 (38%), Positives = 244/436 (56%), Gaps = 11/436 (2%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K +LHW +G+ R + RR D A L+ D + + +++R+ G + A Sbjct 3 LKTRLHWFFGYGLARATLKVLARRRDPFAELVIDNNRPDNALRLIEQLRARGRMSPVIAG 62 Query 61 YLTVDHRLAHDLLRSDDFRVVSFGENLPPPL-RWLERRTRGDQLHPLREPSLLAVEPPDH 119 ++T D +L ++LR D FR + P + +W +T L+ L PSLL ++PP+H Sbjct 63 WVTADAQLVREMLRDDRFRTAKPHDRSPFRIAQWALAKTNPGVLNGLEPPSLLVIDPPEH 122 Query 120 TRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEIL 179 R R+ VS FT RA+ LR +++ A ++D G D++ Y S++PI VI+E+L Sbjct 123 ERLRRLVSRAFTPRAIDRLRHRIQEIANAVVDDLDGHAG-CDLIADYASRIPIEVIAELL 181 Query 180 GVPEHDRPRVLEFGELAAPSLDIGIP-WRQYLRVQQGIRGFDCWLEGHLQQLRHAPGD-D 237 G+P + P + E A L +P W + +R F+ +++ H+++LR + GD Sbjct 182 GIPREEIPYLHTLAEPGAKLLTTTVPSWADFQTALTALREFERYIDAHIERLRRSGGDTS 241 Query 238 LMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLR 297 ++S +++ ET+L E+R AGL+L AGF TT + GN + L+D P+ LA LR Sbjct 242 ILSAVLE-------ETELTRLEVRMFAGLLLGAGFITTTHAFGNAVVTLVDHPDQLARLR 294 Query 298 QHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPD 357 +P+ WPN +EE LR + Q ARVA + V++ G + G V + +A ANRDPAVF Sbjct 295 ANPDGWPNAIEETLRYNCVAQFGARVASQTVQIDGHTVLEGSTVFLSIAGANRDPAVFER 354 Query 358 PHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTR 417 P FD R NA H+ F TG H CLGA LAR E VGL+ F+RFPD+ AGA D+ Sbjct 355 PDEFDATRVNARDHIGFGTGVHACLGAPLARMELNVGLQALFERFPDLTLAGAPIPNDST 414 Query 418 VLRGWSTLPVTLGPAR 433 +L G LPV LGPAR Sbjct 415 LLHGIKYLPVHLGPAR 430 >gi|169631531|ref|YP_001705180.1| putative cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169243498|emb|CAM64526.1| Putative cytochrome P450 [Mycobacterium abscessus] Length=428 Score = 246 bits (629), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 155/435 (36%), Positives = 225/435 (52%), Gaps = 16/435 (3%) Query 1 VKDKLHWLAMHGVIRGIAAIGIRRGDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN 60 +K + HW HG+ R + RRG+ A+L D A D D++R G L R Sbjct 5 IKQRTHWAVTHGIGRAYLKVLARRGEPVAQLGIDVGQAPDIYRIIDKIRERGRLSRAGDG 64 Query 61 YLTVDHRLAHDLLRSDDFRVVSFG---ENLPPPLRWLERRTRGDQLHPLREPSLLAVEPP 117 ++T D ++ + R D R V+F + P ++ L + L+P PS+L +PP Sbjct 65 WITADAQIVRTIFR--DNRFVTFKPEHRSASPIIQRLAAWSDPQLLNPAEPPSILITDPP 122 Query 118 DHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISE 177 DH R R+ V+A FT RA+ LRD +++ LD +Q D++ + +++PI VI E Sbjct 123 DHGRLRRLVAAPFTPRAIEGLRDRIQEVTNGHLDVL-QQRQSPDLIADFTAKIPIAVIGE 181 Query 178 ILGVPEHDRPRVLEFGELAAPSLDIGIP-WRQYLRVQQGIRGFDCWLEGHLQQLR-HAPG 235 ++ VP D R+ A + P W +Y +R D +LE H+ +LR Sbjct 182 MIAVPPPDYSRLYTAMNRAIQLIATTAPSWSEYQDGTAALREIDEYLEKHVARLRREGTE 241 Query 236 DDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLAT 295 +L + L+ ++ L EL+ + L AGF TT +L+G I LL PE LA Sbjct 242 SELATALL--------DSDLSHFELKMFFAVFLGAGFVTTTHLMGKAIVTLLRHPEQLAL 293 Query 296 LRQHPELWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVF 355 L+ P LWPN VEE++R D+ Q +ARVA VE+ G I+ G+ ++ L ANRDPA F Sbjct 294 LQADPSLWPNAVEELMRYDTSNQWSARVATETVEIEGHTIEAGQSALLLLGGANRDPAAF 353 Query 356 PDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRD 415 +P FDI RPNA ++ TG H CLG LARAE L+T F+RFP + AG + Sbjct 354 ENPDVFDITRPNARENITLGTGIHVCLGQVLARAELHTALQTLFERFPRLSLAGEPEYLN 413 Query 416 TRVLRGWSTLPVTLG 430 + G LPVTLG Sbjct 414 GMGIHGLRLLPVTLG 428 >gi|256397594|ref|YP_003119158.1| cytochrome P450 [Catenulispora acidiphila DSM 44928] gi|256363820|gb|ACU77317.1| cytochrome P450 [Catenulispora acidiphila DSM 44928] Length=409 Score = 242 bits (618), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 149/391 (39%), Positives = 206/391 (53%), Gaps = 28/391 (7%) Query 40 DPVPFYDEVRSHGALVRN-RANYLTVDHRLAHDLLRSDDFRVVSFGENLPPPLRWLERRT 98 DP Y ++R +G L R R N+ TV HR+ + +LR +RR Sbjct 43 DPYAIYRQMRQYGPLYRTARGNWSTVSHRVCNTVLR--------------------DRRL 82 Query 99 RGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVSALRDLVEQTAINLLDRFAEQPG 158 +Q L + S+L + PPDHTR R+ F+ + + R +E+T +LLDR G Sbjct 83 GVEQDEYL-DLSMLGMNPPDHTRLRRLAQPAFSPKTLPTFRARIERTVADLLDRAESPGG 141 Query 159 IVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRG 218 D+V + + LPI VI+E+LG+P+ D E G +LD Q R Q Sbjct 142 SFDLVSAFAAPLPISVITELLGIPDADNREFAEHGATVGSALDGIQSLGQAARFQASQAA 201 Query 219 FDCWLEGHLQQLRHAPGDDLMSQLIQIAESGDNETQLDETELRAIAGLVLVAGFETTVNL 278 E R P DDL+S LI A GD Q+ +EL + L+L+AGFETTVNL Sbjct 202 LHTLFENLFALRRREPADDLISHLI--AAEGD---QIQPSELEPMVFLLLIAGFETTVNL 256 Query 279 LGNGIRMLLDTPEHLATLRQHPE-LWPNTVEEILRLDSPVQLTARVACRDVEVAGVRIKR 337 +GN LL+ P+ LR PE L P VEE LR D PVQ T+R+A +D+E+ G I + Sbjct 257 IGNSTLALLNNPDQWEALRADPENLAPKAVEEALRYDPPVQGTSRLALQDLELEGQHIHQ 316 Query 338 GEVVVIYLAAANRDPAVFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARAEGEVGLRT 397 G+ + LAAA RDP ++P P FDI R + HLAFS+G H+C+G LAR E + L+T Sbjct 317 GQRIFTMLAAAGRDPEIYPHPDTFDIARESPADHLAFSSGIHYCIGQPLARMEATIALQT 376 Query 398 FFDRFPDVRAAGAGSRRDTRVLRGWSTLPVT 428 +R P +R G RR+T +RG L V+ Sbjct 377 LAERMPKLRITGPVRRRNTTTIRGLRQLVVS 407 >gi|134102386|ref|YP_001108047.1| cytochrome p450-like enzyme [Saccharopolyspora erythraea NRRL 2338] gi|291004229|ref|ZP_06562202.1| cytochrome p450-like enzyme [Saccharopolyspora erythraea NRRL 2338] gi|133915009|emb|CAM05122.1| cytochrome p450-like enzyme [Saccharopolyspora erythraea NRRL 2338] Length=433 Score = 236 bits (603), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 169/427 (40%), Positives = 224/427 (53%), Gaps = 18/427 (4%) Query 8 LAMHGVIRGIAAIGIRR-GDLQARLIADPAVATDPVPFYDEVRSHGALVRNRAN-YLTVD 65 L M V+ G I R GD ARL+ P DP P Y ++R+ G LVR+R + Sbjct 17 LGMRLVLHGAVTWSIARLGDPVARLLHSP-WRRDPYPIYRQLRARGPLVRSRLGVWAAST 75 Query 66 HRLAHDLLRSDDFRVVSFGENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKT 125 + + +LR F V + + P G QL SLL ++PPDHTR RK Sbjct 76 YEVCDAVLRDRRFGVRTSDGSYGDP----TAAAVGLQL------SLLELDPPDHTRLRKL 125 Query 126 VSAVFTSRAVSALRDLVEQTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHD 185 + F R + R +E TA LLDR A G D++ + + LPI VI E+LG+PE Sbjct 126 AAPAFRPRKLENYRQRIEDTAHELLDR-ALAKGEFDLIRDFATPLPIRVICELLGLPELG 184 Query 186 RPRVLEFGELAAPSLDIGIPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQI 245 R+ G + +LD R R++ + ++Q R PG+D++S L+ Sbjct 185 AERLAVHGAALSGALDGIRSIRHLRRMRASTLELNELFGDLIEQRRRQPGEDIVSDLV-- 242 Query 246 AESGDNETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPN 305 + ++ +LD TEL + L+LVAGFETTVNL+GNG+ LL+ P+ L P+ Sbjct 243 --TALDQDRLDSTELVQMCDLLLVAGFETTVNLIGNGVLALLERPDQWRLLCDDPDQAVG 300 Query 306 TVEEILRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIER 365 VEE LR D PVQ T RVA VEVAG + R V+ L AA RDPAV P RFDI R Sbjct 301 VVEETLRWDPPVQTTMRVAHEPVEVAGRLLPRNSAVLPMLGAAGRDPAVHFAPDRFDITR 360 Query 366 PNAGRHLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTL 425 G HLAFS+G H+CLGA LAR E E+ R R P++R +GA RR T V+ G S L Sbjct 361 GTRGDHLAFSSGIHYCLGAPLARLESEIAFRCLATRVPELRRSGALVRRPTSVIHGLSAL 420 Query 426 PVTLGPA 432 PV A Sbjct 421 PVAASKA 427 >gi|37521511|ref|NP_924888.1| cytochrome P-450 like protein [Gloeobacter violaceus PCC 7421] gi|35212508|dbj|BAC89883.1| cytochrome P-450 like protein [Gloeobacter violaceus PCC 7421] Length=423 Score = 236 bits (603), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 151/402 (38%), Positives = 207/402 (52%), Gaps = 9/402 (2%) Query 32 IADPAVATDPVPFYDEVRSHGALVRN-RANYLTVDHRLAHDLLRSDDFRVVSFGENLPPP 90 + DPA DP PFYD +R + RN ++ + +LR FRV+ + Sbjct 27 VFDPAFHEDPYPFYDRLRRESPIYRNFMGAWVFTRYSDIKSILRDRRFRVLDKPGWIKNK 86 Query 91 LRWLE-RRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVSALRDLVEQTAINL 149 R+L + D L +EPPDH R R ++ F++ V LR VE T +L Sbjct 87 NRYLTPDQGNFDALVRSSSKFFFFLEPPDHGRLRGLITKAFSASFVDRLRPHVEATLADL 146 Query 150 LDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELAAPSLDIGIPWRQY 209 L + EQ G +D++ LP +VI+ ++GVP D R+ + A D I Y Sbjct 147 LGKVREQ-GAMDIMADLACPLPAIVIARLIGVPAADYARLGHLSDELARIFDPVISLEGY 205 Query 210 LRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESGDNETQLDETELRAIAGLVLV 269 L + + F + + + + PG DL+ LI E G+ +L E E+ A+ + Sbjct 206 LHLNAVVEEFGSYFLDLVAEHKRQPGTDLIDSLIAAQEEGN---RLSEEEVVAVCMQLFA 262 Query 270 AGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEEILRLDSPVQLTARVACRDVE 329 G ETTVNL+GNG+ LL PE L LR PE+ VEE+LR DS +QL AR A D+E Sbjct 263 GGEETTVNLIGNGMLALLTHPEQLELLRSKPEIIAGAVEELLRYDSSIQLVARAAIEDIE 322 Query 330 VAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAGRHLAFSTGRHFCLGAALARA 389 + G I GE V +YL AANRDPA F DPH D+ R + RHLAF G H C G LAR Sbjct 323 IEGCTIGAGEHVHLYLGAANRDPAQFFDPHSLDLTRVD-NRHLAFGDGIHHCFGGPLARV 381 Query 390 EGEVGLRTFFDRFPDVRAAGA--GSRRDTRVLRGWSTLPVTL 429 EG+V +T +FP +R A + RR+ +LRG TLPVT Sbjct 382 EGQVVFQTLVQQFPKLRLAESRRPERREGTLLRGLKTLPVTF 423 >gi|15828128|ref|NP_302391.1| cytochrome p450 [Mycobacterium leprae TN] gi|221230605|ref|YP_002504021.1| putative cytochrome p450 [Mycobacterium leprae Br4923] gi|13093682|emb|CAC31043.1| putative cytochrome p450 [Mycobacterium leprae] gi|219933712|emb|CAR72185.1| putative cytochrome p450 [Mycobacterium leprae Br4923] Length=434 Score = 233 bits (593), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 158/417 (38%), Positives = 215/417 (52%), Gaps = 43/417 (10%) Query 30 RLIADPAVATDPVPFYDEVRSHGAL------VRNRANYLTVDHRLAHDLLRSDDFRVVSF 83 RLI DP DP P Y + +G + + +++ D L H L SD + Sbjct 40 RLI-DPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLA 98 Query 84 GENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVSALRDLVE 143 + + G + P S + ++PPDHTR RK VS F + V AL + Sbjct 99 QQAI----------AAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIA 148 Query 144 QTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELAA---PSL 200 +LLD+ A G DV+ L + VI +LGVP D P EFG ++A S+ Sbjct 149 ALVDSLLDKGAAA-GQFDVIADLAFPLAVAVICRLLGVPYEDAP---EFGRVSALLVQSV 204 Query 201 DIGI------PWRQYLRVQQGIRGFDCWLEGHLQQL----RHAPGDDLMSQLIQIAESGD 250 D I P R++ G+ WL +L+QL R PG+DL+S+LI++ ESGD Sbjct 205 DPFITITGEPPEATEERLRAGV-----WLRDYLEQLVKCRRGTPGEDLISRLIELDESGD 259 Query 251 NETQLDETELRAIAGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEEI 310 QL E E+ A GL+LVAG ETTVNL+ N + +L P L +P+ P VEE Sbjct 260 ---QLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEET 316 Query 311 LRLDSPVQLTARVACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAGR 370 LR D + L RVA +D+ + + G+ +V+ LAAANRDPAV+ P FD +RP++ R Sbjct 317 LRYDPAIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSS-R 375 Query 371 HLAFSTGRHFCLGAALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPV 427 HLAF+ G HFCLGAALAR E V L RFP V+ AG + +RG S LPV Sbjct 376 HLAFAVGSHFCLGAALARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSALPV 432 >gi|297561171|ref|YP_003680145.1| cytochrome P450 [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296845619|gb|ADH67639.1| cytochrome P450 [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=417 Score = 228 bits (582), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 147/407 (37%), Positives = 203/407 (50%), Gaps = 19/407 (4%) Query 25 GDLQARLIADPAVATDPVPFYDEVRSHGALVRNRANYLTVD-HRLAHDLLRSDDFRVVSF 83 GD +RL+ P +P P Y +R G ++ + T + ++ LLR +F V Sbjct 27 GDHPSRLLHYP-WRDNPYPTYQRLRDQGHFATSKLGFRTANTYQAVSALLRGREFGVQPP 85 Query 84 GENLPPPLRWLERRTRGDQLHPLREPSLLAVEPPDHTRYRKTVSAVFTSRAVSALRDLVE 143 PP Q + + S L +PP+HTR R+ F+ R +S + Sbjct 86 DGTAPP------------QQFDILDLSFLMKDPPEHTRLRQLARPAFSPRRMSEYETHIT 133 Query 144 QTAINLLDRFAEQPGIVDVVGRYCSQLPIVVISEILGVPEHDRPRVLEFGELAAPSLDIG 203 + LLD+ A G D++ + LPI VIS +LGVP + G +LD Sbjct 134 KITHELLDK-ATAKGHFDLMRDFAQPLPIAVISHLLGVPAAQDAEFVRIGHALGSALDGA 192 Query 204 IPWRQYLRVQQGIRGFDCWLEGHLQQLRHAPGDDLMSQLIQIAESGDNETQLDETELRAI 263 + Q D ++Q R P DD++S L+ A+ G L TEL + Sbjct 193 RSASHLRSIHQATAQLDLLFTRLMRQRRADPRDDVVSTLVTQADDG----HLTATELSTM 248 Query 264 AGLVLVAGFETTVNLLGNGIRMLLDTPEHLATLRQHPELWPNTVEEILRLDSPVQLTARV 323 L+L+AGFETTVNL+GNG+ LL L P+L P VEEILR DSPVQ+T+R Sbjct 249 CRLLLIAGFETTVNLIGNGVMALLRHRHQWERLVADPDLAPGAVEEILRFDSPVQMTSRW 308 Query 324 ACRDVEVAGVRIKRGEVVVIYLAAANRDPAVFPDPHRFDIERPNAGRHLAFSTGRHFCLG 383 D V ++RG + + +ANRDPA F DP RFDI RP+A HL+FS+G H+CLG Sbjct 309 VHTDTTVQRQPLRRGGYTMCLIGSANRDPARFTDPDRFDITRPDAADHLSFSSGVHYCLG 368 Query 384 AALARAEGEVGLRTFFDRFPDVRAAGAGSRRDTRVLRGWSTLPVTLG 430 A LAR EG + LR +R P +R +RR T V+R S PVT G Sbjct 369 APLARLEGRIALRALAERLPHLRPTAPPTRRPTAVVRSLSAFPVTTG 415 Lambda K H 0.323 0.140 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 897400889630 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40