BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1913
Length=250
Score E
Sequences producing significant alignments: (Bits) Value
gi|15609050|ref|NP_216429.1| hypothetical protein Rv1913 [Mycoba... 498 4e-139
gi|340626922|ref|YP_004745374.1| hypothetical protein MCAN_19291... 495 2e-138
gi|121637819|ref|YP_978042.1| hypothetical protein BCG_1952 [Myc... 494 4e-138
gi|308231983|ref|ZP_07414475.2| hypothetical protein TMAG_02093 ... 474 5e-132
gi|296164944|ref|ZP_06847500.1| metallo-beta-lactamase superfami... 341 5e-92
gi|240172595|ref|ZP_04751254.1| hypothetical protein MkanA1_2499... 341 6e-92
gi|254821862|ref|ZP_05226863.1| hypothetical protein MintA_18152... 341 7e-92
gi|254775262|ref|ZP_05216778.1| metallo-beta-lactamase [Mycobact... 338 3e-91
gi|336457401|gb|EGO36410.1| Zn-dependent hydrolase, glyoxylase [... 328 6e-88
gi|41407740|ref|NP_960576.1| hypothetical protein MAP1642 [Mycob... 326 2e-87
gi|183982823|ref|YP_001851114.1| hypothetical protein MMAR_2819 ... 323 1e-86
gi|118465221|ref|YP_881970.1| metallo-beta-lactamase [Mycobacter... 320 2e-85
gi|342859570|ref|ZP_08716223.1| hypothetical protein MCOL_11843 ... 308 7e-82
gi|120404375|ref|YP_954204.1| beta-lactamase domain-containing p... 259 2e-67
gi|315444046|ref|YP_004076925.1| Zn-dependent hydrolase, glyoxyl... 233 2e-59
gi|145223718|ref|YP_001134396.1| beta-lactamase domain-containin... 229 2e-58
gi|297160566|gb|ADI10278.1| metallo-beta-lactamase [Streptomyces... 200 1e-49
gi|345015102|ref|YP_004817456.1| hypothetical protein Strvi_7846... 195 4e-48
gi|294629287|ref|ZP_06707847.1| metallo-beta-lactamase superfami... 190 2e-46
gi|344999559|ref|YP_004802413.1| putative metallo-beta-lactamase... 187 1e-45
gi|320010889|gb|ADW05739.1| beta-lactamase domain protein [Strep... 185 6e-45
gi|254392597|ref|ZP_05007774.1| metallo-beta-lactamase [Streptom... 185 7e-45
gi|328882382|emb|CCA55621.1| putative metallo-beta-lactamase [St... 182 6e-44
gi|239987532|ref|ZP_04708196.1| putative metallo-beta-lactamase ... 181 7e-44
gi|297194441|ref|ZP_06911839.1| metallo-beta-lactamase [Streptom... 180 1e-43
gi|337765609|emb|CCB74318.1| Metallo-beta-lactamase [Streptomyce... 179 3e-43
gi|297199597|ref|ZP_06916994.1| metallo-beta-lactamase [Streptom... 178 5e-43
gi|302545467|ref|ZP_07297809.1| metallo-beta-lactamase superfami... 178 7e-43
gi|291439728|ref|ZP_06579118.1| metallo-beta-lactamase [Streptom... 175 5e-42
gi|302551340|ref|ZP_07303682.1| metallo-beta-lactamase [Streptom... 175 7e-42
gi|329934632|ref|ZP_08284673.1| putative metallo-beta-lactamase ... 174 1e-41
gi|21221015|ref|NP_626794.1| hypothetical protein SCO2556 [Strep... 170 2e-40
gi|289771708|ref|ZP_06531086.1| metallo-beta-lactamase [Streptom... 169 4e-40
gi|29832111|ref|NP_826745.1| metallo-beta-lactamase [Streptomyce... 164 2e-38
gi|290960534|ref|YP_003491716.1| hypothetical protein SCAB_61541... 162 4e-38
gi|254382704|ref|ZP_04998061.1| metallo-beta-lactamase [Streptom... 160 1e-37
gi|302519003|ref|ZP_07271345.1| metallo-beta-lactamase [Streptom... 157 1e-36
gi|333027166|ref|ZP_08455230.1| putative metallo-beta-lactamase ... 156 2e-36
gi|291451261|ref|ZP_06590651.1| metallo-beta-lactamase [Streptom... 154 1e-35
gi|302534344|ref|ZP_07286686.1| metallo-beta-lactamase [Streptom... 154 2e-35
gi|182438785|ref|YP_001826504.1| putative metallo-beta-lactamase... 153 3e-35
gi|326779440|ref|ZP_08238705.1| beta-lactamase domain protein [S... 152 4e-35
gi|317125974|ref|YP_004100086.1| beta-lactamase [Intrasporangium... 123 2e-26
gi|134097934|ref|YP_001103595.1| metallo-beta-lactamase [Sacchar... 120 2e-25
gi|284030353|ref|YP_003380284.1| beta-lactamase domain-containin... 114 1e-23
gi|291299170|ref|YP_003510448.1| beta-lactamase domain-containin... 114 1e-23
gi|119716134|ref|YP_923099.1| beta-lactamase domain-containing p... 112 6e-23
gi|313837298|gb|EFS75012.1| metallo-beta-lactamase domain protei... 108 8e-22
gi|314928028|gb|EFS91859.1| metallo-beta-lactamase domain protei... 107 1e-21
gi|328907153|gb|EGG26919.1| metallo-beta-lactamase domain protei... 107 1e-21
>gi|15609050|ref|NP_216429.1| hypothetical protein Rv1913 [Mycobacterium tuberculosis H37Rv]
gi|15841385|ref|NP_336422.1| hypothetical protein MT1964 [Mycobacterium tuberculosis CDC1551]
gi|31793106|ref|NP_855599.1| hypothetical protein Mb1948 [Mycobacterium bovis AF2122/97]
48 more sequence titles
Length=250
Score = 498 bits (1281), Expect = 4e-139, Method: Compositional matrix adjust.
Identities = 249/250 (99%), Positives = 250/250 (100%), Gaps = 0/250 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV
Sbjct 1 MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA
Sbjct 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES
Sbjct 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR
Sbjct 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
Query 241 ETPATLPCKR 250
ETPATLPCKR
Sbjct 241 ETPATLPCKR 250
>gi|340626922|ref|YP_004745374.1| hypothetical protein MCAN_19291 [Mycobacterium canettii CIPT
140010059]
gi|340005112|emb|CCC44261.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=250
Score = 495 bits (1275), Expect = 2e-138, Method: Compositional matrix adjust.
Identities = 248/250 (99%), Positives = 249/250 (99%), Gaps = 0/250 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADV QIAGCQV
Sbjct 1 MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVTQIAGCQV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA
Sbjct 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES
Sbjct 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR
Sbjct 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
Query 241 ETPATLPCKR 250
ETPATLPCKR
Sbjct 241 ETPATLPCKR 250
>gi|121637819|ref|YP_978042.1| hypothetical protein BCG_1952 [Mycobacterium bovis BCG str. Pasteur
1173P2]
gi|224990303|ref|YP_002644990.1| hypothetical protein JTY_1936 [Mycobacterium bovis BCG str. Tokyo
172]
gi|121493466|emb|CAL71939.1| Conserved hypothetical protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224773416|dbj|BAH26222.1| hypothetical protein JTY_1936 [Mycobacterium bovis BCG str. Tokyo
172]
gi|341601846|emb|CCC64520.1| conserved hypothetical protein [Mycobacterium bovis BCG str.
Moreau RDJ]
Length=250
Score = 494 bits (1272), Expect = 4e-138, Method: Compositional matrix adjust.
Identities = 248/250 (99%), Positives = 249/250 (99%), Gaps = 0/250 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HFDWE LTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV
Sbjct 1 MHFDWECLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA
Sbjct 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES
Sbjct 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR
Sbjct 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR 240
Query 241 ETPATLPCKR 250
ETPATLPCKR
Sbjct 241 ETPATLPCKR 250
>gi|308231983|ref|ZP_07414475.2| hypothetical protein TMAG_02093 [Mycobacterium tuberculosis SUMu001]
gi|308369560|ref|ZP_07418256.2| hypothetical protein TMBG_00446 [Mycobacterium tuberculosis SUMu002]
gi|308370861|ref|ZP_07422983.2| hypothetical protein TMCG_02955 [Mycobacterium tuberculosis SUMu003]
22 more sequence titles
Length=239
Score = 474 bits (1220), Expect = 5e-132, Method: Compositional matrix adjust.
Identities = 238/239 (99%), Positives = 239/239 (100%), Gaps = 0/239 (0%)
Query 12 VHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFD 71
+HRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFD
Sbjct 1 MHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFD 60
Query 72 HVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYD 131
HVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYD
Sbjct 61 HVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYD 120
Query 132 AAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDL 191
AAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDL
Sbjct 121 AAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDL 180
Query 192 AAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR 250
AAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
Sbjct 181 AAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR 239
>gi|296164944|ref|ZP_06847500.1| metallo-beta-lactamase superfamily protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295899786|gb|EFG79236.1| metallo-beta-lactamase superfamily protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=265
Score = 341 bits (875), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 176/244 (73%), Positives = 199/244 (82%), Gaps = 5/244 (2%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
VHF WERLT VHRCRLPFCDVTVGLVRGR G LLVDTG+TL E AI AD +++ G V
Sbjct 21 VHFAWERLTAGVHRCRLPFCDVTVGLVRGRGGALLVDTGSTLREGAAIDADARRLTGQPV 80
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
TH+VLTHKHFDHVLGSSVF AE++CAPEV++ L S TDR+R DA+ +GAD AE+DRAIA
Sbjct 81 THIVLTHKHFDHVLGSSVFTGAEIYCAPEVLDCLASGTDRMRGDAVHHGADPAEIDRAIA 140
Query 121 ALKPPQHGI----YDAAVDLGDRTVTITHPGSGHTTADLVVVA-PATGHADGPTVVFTGD 175
AL+PP+ GI YDAAVDLGDRTVTI H G GHT +DLVV+A DGPTVVFTGD
Sbjct 141 ALRPPRRGIYRGVYDAAVDLGDRTVTIAHLGRGHTASDLVVIARGGEDDPDGPTVVFTGD 200
Query 176 LVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRA 235
LVEESADP IDADSDLAAWPATLDR+LA+GGP A+YVPGHG+ VDA FVRRQR WL RA
Sbjct 201 LVEESADPAIDADSDLAAWPATLDRLLAVGGPGATYVPGHGRAVDAGFVRRQRDWLARRA 260
Query 236 SRQP 239
+ +P
Sbjct 261 AAEP 264
>gi|240172595|ref|ZP_04751254.1| hypothetical protein MkanA1_24995 [Mycobacterium kansasii ATCC
12478]
Length=239
Score = 341 bits (875), Expect = 6e-92, Method: Compositional matrix adjust.
Identities = 165/232 (72%), Positives = 194/232 (84%), Gaps = 0/232 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+H+ WERLT SV+RCRLPFCDVTVGLV GR LL+D GTTL EA AI AD+ QIA C+V
Sbjct 1 MHYRWERLTASVYRCRLPFCDVTVGLVVGRGTALLIDAGTTLAEAAAIQADISQIAHCRV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
TH+VLTHKHFDHVLGS+ F A+++ APEV ++L SA D+LR AL YGAD ++DRAIA
Sbjct 61 THIVLTHKHFDHVLGSAGFAGAQIYAAPEVADHLSSAADQLRAHALQYGADAVQIDRAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+PP+ GIYDA +DLG R+VT+THPG+GHTTADLVVV P+ + P VVFTGDLVEES
Sbjct 121 ALRPPRRGIYDAVIDLGGRSVTVTHPGAGHTTADLVVVVPSAAASAEPVVVFTGDLVEES 180
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLR 232
ADP IDADSD+AAWPATLDR+LA+GGP+A YVPGHG VVDA+FVRRQR WLR
Sbjct 181 ADPLIDADSDVAAWPATLDRLLALGGPEAIYVPGHGSVVDAEFVRRQRDWLR 232
>gi|254821862|ref|ZP_05226863.1| hypothetical protein MintA_18152 [Mycobacterium intracellulare
ATCC 13950]
Length=237
Score = 341 bits (874), Expect = 7e-92, Method: Compositional matrix adjust.
Identities = 170/234 (73%), Positives = 196/234 (84%), Gaps = 1/234 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HF WE L+ VHRCRL FCDVT+GLVRGRTG LLVD+GTTL EA AI ADV+++AG V
Sbjct 1 MHFGWETLSSGVHRCRLSFCDVTIGLVRGRTGTLLVDSGTTLAEAAAIDADVRRLAGRPV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
+H+VLTHKHFDHVLGSS F +A+++CAPEVV +LRSATD++R +AL YGAD EVD AIA
Sbjct 61 SHIVLTHKHFDHVLGSSFFGRAKIYCAPEVVGHLRSATDQIRAEALRYGADATEVDAAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+PP+ G+YDA+VDLGDRTVTITH G GHT +DLVV+APAT D VVF GDLVEES
Sbjct 121 ALRPPRRGVYDASVDLGDRTVTITHLGRGHTASDLVVIAPATNAGD-RMVVFAGDLVEES 179
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
ADP IDADSD+AAWPATL R+LA+GGPDA YVPGHGKVVDA FV RQR WL R
Sbjct 180 ADPAIDADSDVAAWPATLGRLLAVGGPDAIYVPGHGKVVDAAFVARQRDWLARR 233
>gi|254775262|ref|ZP_05216778.1| metallo-beta-lactamase [Mycobacterium avium subsp. avium ATCC
25291]
Length=237
Score = 338 bits (868), Expect = 3e-91, Method: Compositional matrix adjust.
Identities = 171/236 (73%), Positives = 197/236 (84%), Gaps = 1/236 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HF WERLT SVHRCRLPFCDVTVGL+ GR+G LLVDTGTTL EA AI ADV ++A V
Sbjct 1 MHFAWERLTGSVHRCRLPFCDVTVGLICGRSGTLLVDTGTTLTEAAAIDADVHRLARRPV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
+H+ LTHKHFDHVLGSS+F AEV+CAPEVVEYL +ATD++R+DAL +GAD EVD AIA
Sbjct 61 SHIALTHKHFDHVLGSSLFTGAEVYCAPEVVEYLGAATDQIRDDALRHGADAVEVDAAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+P QHGI DA +DLGDRTVTITH G+GHT +DL ++ PA + PTVVFTGDLVEES
Sbjct 121 ALRPVQHGIRDARIDLGDRTVTITHLGAGHTASDLALIVPAARDGE-PTVVFTGDLVEES 179
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
DP IDADSD+ AWPATLDR+LA+GGP A YVPGHG+VVDA FVRRQR WLR RA+
Sbjct 180 GDPAIDADSDVTAWPATLDRLLALGGPGARYVPGHGRVVDAAFVRRQRDWLRARAA 235
>gi|336457401|gb|EGO36410.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=267
Score = 328 bits (840), Expect = 6e-88, Method: Compositional matrix adjust.
Identities = 177/236 (75%), Positives = 200/236 (85%), Gaps = 1/236 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
VHF WERLT SVHRCRLPFCDVTVGL+ GR+G LLVDTGTTL EA AI ADV ++A V
Sbjct 31 VHFAWERLTGSVHRCRLPFCDVTVGLICGRSGTLLVDTGTTLTEAAAIDADVHRLARRPV 90
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
+H+ LTHKHFDHVLGSS+F AEV+CAPEVVEYL +ATD++R+DAL +GAD AEVD AIA
Sbjct 91 SHIALTHKHFDHVLGSSLFTGAEVYCAPEVVEYLGAATDQIRDDALRHGADAAEVDAAIA 150
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+P QHGI DA +DLGDRTVTITH G+GHT +DLVVV PA + PTVVFTGDLVEES
Sbjct 151 ALRPVQHGIRDARIDLGDRTVTITHLGAGHTASDLVVVVPAARDGE-PTVVFTGDLVEES 209
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
ADP IDADSD+ AWPATLDR+LA+GGP A YVPGHG+VVDA FVRRQR WLR RA+
Sbjct 210 ADPAIDADSDVTAWPATLDRLLALGGPGARYVPGHGRVVDAAFVRRQREWLRARAA 265
>gi|41407740|ref|NP_960576.1| hypothetical protein MAP1642 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396093|gb|AAS03959.1| hypothetical protein MAP_1642 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=237
Score = 326 bits (835), Expect = 2e-87, Method: Compositional matrix adjust.
Identities = 176/236 (75%), Positives = 200/236 (85%), Gaps = 1/236 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+HF WERLT SVHRCRLPFCDVTVGL+ GR+G LLVDTGTTL EA AI ADV ++A V
Sbjct 1 MHFAWERLTGSVHRCRLPFCDVTVGLICGRSGTLLVDTGTTLTEAAAIDADVHRLARRPV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
+H+ LTHKHFDHVLGSS+F AEV+CAPEVVEYL +ATD++R+DAL +GAD AEVD AIA
Sbjct 61 SHIALTHKHFDHVLGSSLFTGAEVYCAPEVVEYLGAATDQIRDDALRHGADAAEVDAAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+P QHGI DA +DLGDRTVTITH G+GHT +DLVVV PA + PTVVFTGDLVEES
Sbjct 121 ALRPVQHGIRDARIDLGDRTVTITHLGAGHTASDLVVVVPAARDGE-PTVVFTGDLVEES 179
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
ADP IDADSD+ AWPATLDR+LA+GGP A YVPGHG+VVDA FVRRQR WLR RA+
Sbjct 180 ADPAIDADSDVTAWPATLDRLLALGGPGARYVPGHGRVVDAAFVRRQREWLRARAA 235
>gi|183982823|ref|YP_001851114.1| hypothetical protein MMAR_2819 [Mycobacterium marinum M]
gi|183176149|gb|ACC41259.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=240
Score = 323 bits (828), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 163/235 (70%), Positives = 189/235 (81%), Gaps = 0/235 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+++DWE+L SV+RCRLPFCDVTVGLV GR LLVD+G+TL EA AI AD++Q+A +V
Sbjct 1 MNYDWEQLPGSVYRCRLPFCDVTVGLVIGRDDALLVDSGSTLREAAAIQADIRQLADRRV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
H+ LTHKHFDHVLGSS F AE++CAPEV EYL SA+ +LREDAL +GAD E+D AIA
Sbjct 61 AHIALTHKHFDHVLGSSAFVGAEIYCAPEVAEYLSSASHQLREDALHHGADAGEIDTAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+PP+H I DA V LGDR V ITH G GHT+ADLVVVA GP VVFTGDLVEES
Sbjct 121 ALRPPRHPILDADVHLGDRRVRITHLGRGHTSADLVVVATPPAAQTGPVVVFTGDLVEES 180
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRA 235
ADP IDADSD+AAWPATL+R+LAIGGPDA YVPGHG VVDA F+R QR WL+ RA
Sbjct 181 ADPAIDADSDVAAWPATLERLLAIGGPDAIYVPGHGSVVDADFIRGQRDWLKQRA 235
>gi|118465221|ref|YP_881970.1| metallo-beta-lactamase [Mycobacterium avium 104]
gi|118166508|gb|ABK67405.1| metallo-beta-lactamase [Mycobacterium avium 104]
Length=237
Score = 320 bits (819), Expect = 2e-85, Method: Compositional matrix adjust.
Identities = 172/236 (73%), Positives = 197/236 (84%), Gaps = 1/236 (0%)
Query 1 VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV 60
+H WERLT SVHRCRLPFCDVTVGL+ GR+G LLVDTGTTL EA AI ADV ++A V
Sbjct 1 MHLAWERLTGSVHRCRLPFCDVTVGLICGRSGTLLVDTGTTLTEAAAIDADVHRLARRPV 60
Query 61 THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA 120
+H+ LTHKHFDHVLGSS+F AEV+CAPEVVEYL +ATD++R+DAL +GAD AEVD AIA
Sbjct 61 SHIALTHKHFDHVLGSSLFTGAEVYCAPEVVEYLGAATDQIRDDALRHGADAAEVDAAIA 120
Query 121 ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
AL+P QHGI DA +DLGDRTVTITH G+GHT +DL V+ PA + PTVVFTGDLVEES
Sbjct 121 ALRPGQHGIRDARIDLGDRTVTITHLGAGHTASDLAVIVPAARDGE-PTVVFTGDLVEES 179
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
DP IDADSD+ AWPATLDR+LA+GGP A YVPGHG+VVDA FVRRQR WLR RA+
Sbjct 180 GDPAIDADSDVTAWPATLDRLLALGGPGARYVPGHGRVVDAAFVRRQRDWLRARAA 235
>gi|342859570|ref|ZP_08716223.1| hypothetical protein MCOL_11843 [Mycobacterium colombiense CECT
3035]
gi|342132702|gb|EGT85922.1| hypothetical protein MCOL_11843 [Mycobacterium colombiense CECT
3035]
Length=237
Score = 308 bits (788), Expect = 7e-82, Method: Compositional matrix adjust.
Identities = 162/232 (70%), Positives = 180/232 (78%), Gaps = 1/232 (0%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERL+ V RCRLPFCDVTVGLV G LLVDTGTTL EA AI ADV++ AG +H+V
Sbjct 5 WERLSSGVQRCRLPFCDVTVGLVWGSGAALLVDTGTTLTEAAAIDADVRRFAGRTASHIV 64
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTHKHFDHVLGS +F A V CAPEV ++L SAT +LREDAL +GAD EVD AIAAL+P
Sbjct 65 LTHKHFDHVLGSGLFTGARVHCAPEVAQHLSSATGQLREDALRHGADPVEVDAAIAALRP 124
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPD 184
G +DA VDLGDRTV I H G GHT +DLVVVAP + VVFTGDLVEESADP
Sbjct 125 ANGGGHDAVVDLGDRTVAIAHLGRGHTASDLVVVAPGRDGGE-RVVVFTGDLVEESADPA 183
Query 185 IDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
IDADSD+AAWPATLDR+LA+GGPDA YVPGHG VVDA FVRRQR WL RA+
Sbjct 184 IDADSDVAAWPATLDRLLAVGGPDAIYVPGHGGVVDAGFVRRQRDWLARRAA 235
>gi|120404375|ref|YP_954204.1| beta-lactamase domain-containing protein [Mycobacterium vanbaalenii
PYR-1]
gi|119957193|gb|ABM14198.1| beta-lactamase domain protein [Mycobacterium vanbaalenii PYR-1]
Length=243
Score = 259 bits (662), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 139/235 (60%), Positives = 159/235 (68%), Gaps = 6/235 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
+WER+T V RCRLPFCDVTVG+V L+VDTGTTL EA A+ DV + C V H
Sbjct 7 LEWERITAQVMRCRLPFCDVTVGVVHAGGEALVVDTGTTLAEARAVVRDVAALTDCVVRH 66
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
VV+TH HFDHVLG S F A+ FC+ EVV + A + LR DA+ +GAD EVD A+AAL
Sbjct 67 VVVTHNHFDHVLGHSAFGGAQTFCSAEVVATMADAGESLRADAIRHGADPCEVDDALAAL 126
Query 123 KPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGP-TVVFTGDLVEESA 181
+PP + D V+LGD VTI HPG GHT DL+VV GP TVVF GDLVEES
Sbjct 127 RPPVGAVCDGVVELGDVVVTIAHPGRGHTAHDLIVVVEG-----GPRTVVFCGDLVEESG 181
Query 182 DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
DP IDA SDL AWP TL RVLA GG A YVPGHG +VDA F+RRQ WL T AS
Sbjct 182 DPCIDAQSDLDAWPGTLRRVLAAGGESAVYVPGHGALVDASFLRRQADWLATAAS 236
>gi|315444046|ref|YP_004076925.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
gi|315262349|gb|ADT99090.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
Length=230
Score = 233 bits (594), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 132/231 (58%), Positives = 151/231 (66%), Gaps = 7/231 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERLT V RCRLPFCDVTVG+V +++D GTTL EA A+A DV ++ GC VTH+V
Sbjct 6 WERLTRHVMRCRLPFCDVTVGVVHSDGAAVVIDCGTTLTEARAVAVDVSELTGCAVTHLV 65
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHVLG VFD A+ FC+PEV L + LR DAL YGAD EVD A+ A P
Sbjct 66 LTHHHFDHVLGHPVFDGAQTFCSPEVTAALHE-REWLRSDALRYGADPQEVDDALTAAVP 124
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGP-TVVFTGDLVEESADP 183
P + V+L V I+HPG GHT DL+ V DG TVVF GDLVEES +P
Sbjct 125 PAVAVPYGTVELAGAVVRISHPGRGHTGHDLIAVV-----TDGQDTVVFCGDLVEESGEP 179
Query 184 DIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+D SD AAWPATL RV+A GG YVPGHG VVDA FVRRQ WL R
Sbjct 180 CVDEQSDPAAWPATLQRVVAAGGESGIYVPGHGAVVDAAFVRRQAQWLAGR 230
>gi|145223718|ref|YP_001134396.1| beta-lactamase domain-containing protein [Mycobacterium gilvum
PYR-GCK]
gi|145216204|gb|ABP45608.1| beta-lactamase domain protein [Mycobacterium gilvum PYR-GCK]
Length=230
Score = 229 bits (585), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 131/231 (57%), Positives = 151/231 (66%), Gaps = 7/231 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERLT V RCRLPFCDVTVG+V +++D GTTL EA A+AADV ++ GC VTH+V
Sbjct 6 WERLTRHVMRCRLPFCDVTVGVVHSDGAAVVIDCGTTLTEARAVAADVSELTGCAVTHLV 65
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHVLG VFD A+ FC+PEV L + LR DAL YGAD EVD A+ A P
Sbjct 66 LTHHHFDHVLGHPVFDGAQTFCSPEVTAALHE-REWLRSDALRYGADPQEVDDALTAAVP 124
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGP-TVVFTGDLVEESADP 183
P + V+L V I+HPG GHT DL+ V DG TVVF GDLVEES +P
Sbjct 125 PAVAVPYGTVELAGVVVRISHPGRGHTGHDLIAVV-----TDGQDTVVFCGDLVEESGEP 179
Query 184 DIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+D SD AAWPATL RV+ GG YVPGHG VV+A FVRRQ WL R
Sbjct 180 CVDDQSDPAAWPATLQRVVDAGGESGIYVPGHGAVVEAAFVRRQAQWLAGR 230
>gi|297160566|gb|ADI10278.1| metallo-beta-lactamase [Streptomyces bingchenggensis BCW-1]
Length=242
Score = 200 bits (509), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 117/235 (50%), Positives = 143/235 (61%), Gaps = 4/235 (1%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WE L SV RCRLP D TVG + GRTG+L+VDTG L E + +V ++ G + TH+
Sbjct 10 WEDLAPSVVRCRLPGWDATVGAIAGRTGVLVVDTGADLAEGAWVRREVTRLFGRRPTHIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHV G++ F EV+ A + E LR D LR+DA+ +GAD A L
Sbjct 70 LTHPHFDHVFGTAAFAGCEVYGAAGLDELLRRERDALRDDAVRHGADPGAATGAADHLVR 129
Query 125 PQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADG-PTVVFTGDLVEESAD 182
P H + + +DLGDR V + + G GHT DL V+ P G A G P VVF GDLVEES
Sbjct 130 PHHLVCGELTLDLGDRPVLLANVGPGHTAHDLAVLVP--GRAPGEPEVVFCGDLVEESGP 187
Query 183 PDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASR 237
P AD+ WPA LDR+LA+GG DA YVPGHG VDA+FVR QR L R R
Sbjct 188 PQAGADAMPGQWPAALDRLLALGGEDAVYVPGHGAAVDARFVRAQRDELAARFGR 242
>gi|345015102|ref|YP_004817456.1| hypothetical protein Strvi_7846 [Streptomyces violaceusniger
Tu 4113]
gi|344041451|gb|AEM87176.1| hypothetical protein Strvi_7846 [Streptomyces violaceusniger
Tu 4113]
Length=252
Score = 195 bits (496), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 117/247 (48%), Positives = 144/247 (59%), Gaps = 9/247 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERL V R RLP D TVG+V GRT IL+VDTG TL + A + ++ G + T +
Sbjct 10 WERLAPGVARRRLPEWDETVGVVVGRTDILVVDTGATLRAGAELRALITRLTGRRPTRIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHVLGS+ F EV+ A + E LR + LREDA+ +G D A+ L
Sbjct 70 LTHPHFDHVLGSAAFAGCEVYGATGMDELLRRERETLREDAIRHGVDRDAATEAVDHLVG 129
Query 125 PQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADP 183
P H + + +DLGDR V + + G GHT DL V+ P P VVF GDLVEES P
Sbjct 130 PHHLVSGELTLDLGDRPVLLANVGPGHTAHDLAVLVPGR-----PEVVFCGDLVEESGPP 184
Query 184 DIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR---ASRQPR 240
D+ WPA LDR+LA+GGPDA YVPGHG VVDA FVR QR L R + + P
Sbjct 185 QAGPDAIPGRWPAALDRLLALGGPDARYVPGHGSVVDAGFVRAQRDELAARFGVSLQAPT 244
Query 241 ETPATLP 247
+ P P
Sbjct 245 QAPTQPP 251
>gi|294629287|ref|ZP_06707847.1| metallo-beta-lactamase superfamily protein [Streptomyces sp.
e14]
gi|292832620|gb|EFF90969.1| metallo-beta-lactamase superfamily protein [Streptomyces sp.
e14]
Length=243
Score = 190 bits (483), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 117/242 (49%), Positives = 138/242 (58%), Gaps = 9/242 (3%)
Query 2 HFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVT 61
WERL D V R RLP D T+GLV G LLVD G++L E + AD ++AG VT
Sbjct 7 ELGWERLADGVGRVRLPGWDCTIGLVAGAGAALLVDAGSSLAEGARLRADAARLAGTDVT 66
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAI 119
+ LTH HFDHVLG++ F AEVF A A +R LREDA+ +G D E D A
Sbjct 67 LLALTHPHFDHVLGAAAFPAAEVFAAAGSHAVYDDARERAELREDAVRHGLDPREADEAA 126
Query 120 AALKPPQHGIYDA-AVDLG-DRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
AAL P + D AV LG R + + G GHT DL V+ P VVF GDLV
Sbjct 127 AALVRPGREVADVLAVPLGRGREALLANAGPGHTAHDLAVLVPGE-----RPVVFCGDLV 181
Query 178 EESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASR 237
EES +P D+ + WPA LDR+L +GGPDA YVPGHG VVDA FVR QR L R
Sbjct 182 EESGEPQAGPDAVPSRWPAALDRLLELGGPDAVYVPGHGAVVDADFVRAQRDALARRFGV 241
Query 238 QP 239
P
Sbjct 242 SP 243
>gi|344999559|ref|YP_004802413.1| putative metallo-beta-lactamase [Streptomyces sp. SirexAA-E]
gi|344315185|gb|AEN09873.1| putative metallo-beta-lactamase [Streptomyces sp. SirexAA-E]
Length=240
Score = 187 bits (475), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 111/234 (48%), Positives = 135/234 (58%), Gaps = 7/234 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
F WERL D R RLP D T LV G G LL DTG+TL E + A + + G +VTH
Sbjct 8 FGWERLGDGTGRRRLPRWDATAALVAGAEGALLYDTGSTLREGAELRAQAEGLLGRRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
+ L+H HFDHVLG++ F AEV+ A E L LR DAL +G D + A AL
Sbjct 68 IALSHPHFDHVLGTAAFAGAEVYGAVGTAELLSRGAAELRADALRHGVDEEDATAATDAL 127
Query 123 KPPQHGIY-DAAVDLGDR-TVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
P+H + D +DLG V + + G GH+ DL V+ P + P VV GDLVEES
Sbjct 128 VVPRHQVSGDWTLDLGGGLQVLLANVGPGHSGHDLAVLVPGS-----PVVVLCGDLVEES 182
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P D+ A WPA LDR+L +GG DA YVPGHG VVDA FVR QRA L R
Sbjct 183 GEPQAGPDAVPARWPAALDRLLELGGEDALYVPGHGAVVDAAFVRAQRARLADR 236
>gi|320010889|gb|ADW05739.1| beta-lactamase domain protein [Streptomyces flavogriseus ATCC
33331]
Length=240
Score = 185 bits (469), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 107/234 (46%), Positives = 136/234 (59%), Gaps = 7/234 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
F WERL + R RLP D TV LV G G+LL DTG+TL E + + + G +VTH
Sbjct 8 FGWERLGNGTGRRRLPVWDATVALVAGADGVLLYDTGSTLREGVELRTQAEALLGRRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
+ L+H HFDHVLG++ F AEV+ A + L + LR DAL +G A+ A AL
Sbjct 68 IALSHPHFDHVLGTAAFSGAEVYGAVGTADLLARGAEELRADALRHGMSEADATVATDAL 127
Query 123 KPPQHGIY-DAAVDLGDR-TVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
P+H + + +DLGD V + + G GH+ DL V+ P + P VV GDLVEES
Sbjct 128 VSPRHQVTGEWTLDLGDGFQVLLANVGPGHSGHDLAVLVPGS-----PVVVLCGDLVEES 182
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P D+ WPA LDR+L +GG DA YVPGHG VVDA FVR QR L R
Sbjct 183 GEPQAGRDAVPTHWPAALDRLLELGGEDALYVPGHGAVVDAAFVRAQRDRLAVR 236
>gi|254392597|ref|ZP_05007774.1| metallo-beta-lactamase [Streptomyces clavuligerus ATCC 27064]
gi|294812563|ref|ZP_06771206.1| Metallo-beta-lactamase [Streptomyces clavuligerus ATCC 27064]
gi|326440984|ref|ZP_08215718.1| hypothetical protein SclaA2_07945 [Streptomyces clavuligerus
ATCC 27064]
gi|197706261|gb|EDY52073.1| metallo-beta-lactamase [Streptomyces clavuligerus ATCC 27064]
gi|294325162|gb|EFG06805.1| Metallo-beta-lactamase [Streptomyces clavuligerus ATCC 27064]
Length=241
Score = 185 bits (469), Expect = 7e-45, Method: Compositional matrix adjust.
Identities = 115/235 (49%), Positives = 142/235 (61%), Gaps = 8/235 (3%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQI-AGCQVT 61
WERL V R RLP D T GL+ G G+LL DTG+TL E T + V+ + AG VT
Sbjct 8 LGWERLAAGVGRRRLPGWDATCGLIVGTEGVLLYDTGSTLTEGTELRVQVETLLAGRHVT 67
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAA 121
H+ L+H HFDHV+G++ F AEVF A + LR + LR DA+ +G D AE R+
Sbjct 68 HIALSHPHFDHVMGTAAFPGAEVFGAVGLDALLRREREELRSDAVRHGVDGAEAARSAEL 127
Query 122 LKPPQHGIY-DAAVDLGD-RTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEE 179
L P H + + +DLG R V + + G GHT DL V+ P P VVF GDLVEE
Sbjct 128 LVAPGHLVTGERMLDLGGGRRVLLANVGPGHTGHDLAVLVPGE-----PEVVFCGDLVEE 182
Query 180 SADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
S +P D+ A WPA LDR+LA+GG DA+YVPGHG VVDA FVR QRA L R
Sbjct 183 SGEPQAGPDAIGARWPAALDRLLALGGEDAAYVPGHGAVVDAAFVRAQRAALAER 237
>gi|328882382|emb|CCA55621.1| putative metallo-beta-lactamase [Streptomyces venezuelae ATCC
10712]
Length=242
Score = 182 bits (461), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 110/238 (47%), Positives = 138/238 (58%), Gaps = 9/238 (3%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQ-VT 61
+ WERL D V R RLP D TVGLV G +LL DTG++L E + + + G + VT
Sbjct 8 YGWERLADGVGRRRLPGWDATVGLVLGERAVLLYDTGSSLAEGAELRTQIAGLTGGRRVT 67
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAI 119
H+ L+H HFDHVLG++ F AEVF A E L A +R LREDA+ G D A
Sbjct 68 HIALSHPHFDHVLGTAAFAGAEVFGAVGSDELLGRAREREALREDAVRQGLDATAAAEAA 127
Query 120 AALKPPQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVE 178
L P+H + + +DLG R V + + G GH+ DL ++ P + VVF GDLVE
Sbjct 128 DVLVAPRHVVSGEWTLDLGGRQVLLANVGPGHSGHDLALLVPGS-----REVVFCGDLVE 182
Query 179 ESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRAS 236
ES +P D+ A WP LDR+L +GG DA YVPGHG VVDA FVR QR L R S
Sbjct 183 ESGEPQAGPDAIPARWPDALDRLLGLGGEDAVYVPGHGAVVDAPFVRLQREELARRFS 240
>gi|239987532|ref|ZP_04708196.1| putative metallo-beta-lactamase [Streptomyces roseosporus NRRL
11379]
gi|291444493|ref|ZP_06583883.1| metallo-beta-lactamase [Streptomyces roseosporus NRRL 15998]
gi|291347440|gb|EFE74344.1| metallo-beta-lactamase [Streptomyces roseosporus NRRL 15998]
Length=243
Score = 181 bits (460), Expect = 7e-44, Method: Compositional matrix adjust.
Identities = 106/232 (46%), Positives = 136/232 (59%), Gaps = 4/232 (1%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERL + V R RLP D TV LV G G+LL DTG+TL E + + + G +VTH+
Sbjct 10 WERLGNGVGRRRLPGWDATVALVAGTEGVLLYDTGSTLREGVELRRQAEALLGRRVTHIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
L+H HFDHVLG++ F +V+ + + LR L DA+ +G E R+ L
Sbjct 70 LSHPHFDHVLGTAAFAGVQVYGSAGLAALLRDGEQGLYGDAVRHGVSEDEAARSADTLVV 129
Query 125 PQHGI-YDAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESAD 182
P+H + + A+DL G R V + G H++ DL VV P + A P VV GDLVEES D
Sbjct 130 PRHEVDGEQALDLGGGRRVLLADLGPAHSSHDLAVVVPGSDGA--PPVVLCGDLVEESGD 187
Query 183 PDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
P D+ WPA LDR+L +GG DA YVPGHG VVDA FVR+QRA L R
Sbjct 188 PQAGPDAVPGRWPAALDRLLELGGEDALYVPGHGAVVDAAFVRKQRAALAER 239
>gi|297194441|ref|ZP_06911839.1| metallo-beta-lactamase [Streptomyces pristinaespiralis ATCC 25486]
gi|197718750|gb|EDY62658.1| metallo-beta-lactamase [Streptomyces pristinaespiralis ATCC 25486]
Length=240
Score = 180 bits (457), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 108/234 (47%), Positives = 137/234 (59%), Gaps = 7/234 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQI-AGCQVT 61
F WERL D V R RLP D TVGL+ G +LL DTG+TL E + A + + G +VT
Sbjct 8 FGWERLADGVGRRRLPGWDATVGLIVGEDAVLLYDTGSTLREGAEVRAQAQALLGGRRVT 67
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAA 121
H+ L+H HFDHVLG++ F AEV+ A + LR D +R A+ +G D E A
Sbjct 68 HIALSHPHFDHVLGTAAFAGAEVYGAVGMDTLLRRERDSIRASAIRHGVDADEAAEAADM 127
Query 122 LKPPQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
+ P H + + +DLG R V + + G H+ DLV++ PA VVF GDLVEES
Sbjct 128 VVAPHHPVSGECTLDLGGRQVLLANVGPAHSGHDLVLLVPAE-----REVVFCGDLVEES 182
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P D+ WPA LDR+LA+GG DA YVPGHG VVDA FVR QR L R
Sbjct 183 GEPQAGQDAIGPRWPAALDRLLALGGEDALYVPGHGAVVDAAFVRAQRDGLAAR 236
>gi|337765609|emb|CCB74318.1| Metallo-beta-lactamase [Streptomyces cattleya NRRL 8057]
Length=238
Score = 179 bits (455), Expect = 3e-43, Method: Compositional matrix adjust.
Identities = 108/231 (47%), Positives = 134/231 (59%), Gaps = 6/231 (2%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERL V R RL F DVT+G+V G G+LL+D+G+T+ E + +V+ + G VTH+
Sbjct 9 WERLAPGVARRRLAFLDVTIGVVVGTDGVLLIDSGSTVPEGERLRREVRDLTGRDVTHLA 68
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHVLG+S F +A V+ + L L EDA+ YG E RA+ AL
Sbjct 69 LTHAHFDHVLGASAFPEAAVYGQAGLAGVLARGRAELGEDAVRYGVAGPEARRAVDALVT 128
Query 125 PQHGI-YDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADP 183
P H + A+DLG R + HPG GHT DL A P VVF GDLVEES +P
Sbjct 129 PGHPVDRRHALDLGGREALLVHPGPGHTGHDL-----AVVVPGTPVVVFCGDLVEESGEP 183
Query 184 DIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
D+ WPA LD +L +GG A YVPGHG VVDA+FVR QR L R
Sbjct 184 QAGPDAVPGRWPAALDALLELGGETAVYVPGHGAVVDARFVRAQRDALARR 234
>gi|297199597|ref|ZP_06916994.1| metallo-beta-lactamase [Streptomyces sviceus ATCC 29083]
gi|197713475|gb|EDY57509.1| metallo-beta-lactamase [Streptomyces sviceus ATCC 29083]
Length=242
Score = 178 bits (452), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 114/236 (49%), Positives = 137/236 (59%), Gaps = 9/236 (3%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
WER+ V RCRLP D T GLV G LLVD G+ L E + A ++AG +VTH
Sbjct 8 LGWERVATGVGRCRLPGWDCTAGLVIGEGTALLVDAGSGLAEGARLRAQAGELAGHRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAIA 120
+ LTH HFDHV G++ F AEVF A V L R LR DA+ G D A D A+
Sbjct 68 LALTHPHFDHVFGAAAFAGAEVFGAVGVETVLAGRLGRAELRADAVRNGLDPAVADEAVD 127
Query 121 ALKPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVE 178
AL P+H + + +DL G R V + + G GHT DLVV+ P + P VVF GDLVE
Sbjct 128 ALVSPRHHVSGEWTLDLGGGRQVLLANVGPGHTAHDLVVLVPGS-----PEVVFCGDLVE 182
Query 179 ESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
ES +P D+ WPA LDR+L +GG DA YVPGHG VVDA FVR QR L R
Sbjct 183 ESGEPQAGPDAVPQHWPAALDRLLDLGGEDAQYVPGHGAVVDAAFVRAQRDALAAR 238
>gi|302545467|ref|ZP_07297809.1| metallo-beta-lactamase superfamily protein [Streptomyces hygroscopicus
ATCC 53653]
gi|302463085|gb|EFL26178.1| metallo-beta-lactamase superfamily protein [Streptomyces himastatinicus
ATCC 53653]
Length=244
Score = 178 bits (451), Expect = 7e-43, Method: Compositional matrix adjust.
Identities = 111/232 (48%), Positives = 142/232 (62%), Gaps = 4/232 (1%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WE+L V RCRLP D TVG+V G T +L+VDTG++L E A+ A++ ++ G + T +
Sbjct 10 WEQLAPDVARCRLPDWDCTVGVVVGDTDVLVVDTGSSLREGAALRAEITRLTGRRPTRIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
LTH HFDHVLG++ F V+ A + LR D LREDA+ +G A+ L P
Sbjct 70 LTHPHFDHVLGTAAFAGCAVYGATGLDALLRRDRDALREDAIRHGVAPDAAAEAVDHLVP 129
Query 125 PQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADG-PTVVFTGDLVEESAD 182
P H + + +DLG R+V + + G GHT DL V+ P G G P VVF GDLVEES
Sbjct 130 PHHAVSGEVTLDLGGRSVLLANVGPGHTAHDLAVLVP--GRVPGQPEVVFCGDLVEESGP 187
Query 183 PDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
P D+ A WPA LDR++A+GG DA YVPGHG VVDA FVR QR L R
Sbjct 188 PQAGPDAIPAHWPAALDRLIALGGEDARYVPGHGSVVDAAFVRDQRDELAAR 239
>gi|291439728|ref|ZP_06579118.1| metallo-beta-lactamase [Streptomyces ghanaensis ATCC 14672]
gi|291342623|gb|EFE69579.1| metallo-beta-lactamase [Streptomyces ghanaensis ATCC 14672]
Length=248
Score = 175 bits (444), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 106/237 (45%), Positives = 135/237 (57%), Gaps = 12/237 (5%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WER+ V RCRLP D T GLV G +LLVD G++L E + A+ + + G +VTH+
Sbjct 10 WERVAPGVGRCRLPGWDCTAGLVVGADAVLLVDAGSSLAEGARLRAEAQALTGRRVTHLA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRS---ATDRLREDALSYGADTAEVDRAIAA 121
LTH HFDHVLG++ F AEVF A + + LR DA+ +G D + A+
Sbjct 70 LTHPHFDHVLGAAAFAGAEVFGAEGAEGADAAPAYGREELRADAVRHGLDARAAEEAVDV 129
Query 122 LKPPQHGIY-DAAVDL---GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
L P + + A+DL G R V + G GHT DL V+ P P VVF GDLV
Sbjct 130 LVRPHRTVRGELALDLGPGGGRQVLLADVGPGHTAHDLAVLVPGD-----PGVVFCGDLV 184
Query 178 EESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
EES +P D+ + WPA LDR+L +GG +A YVPGHG VVDA FVR QR L R
Sbjct 185 EESGEPQAGPDAVPSHWPAALDRLLELGGEEARYVPGHGAVVDAAFVRAQRDALAAR 241
>gi|302551340|ref|ZP_07303682.1| metallo-beta-lactamase [Streptomyces viridochromogenes DSM 40736]
gi|302468958|gb|EFL32051.1| metallo-beta-lactamase [Streptomyces viridochromogenes DSM 40736]
Length=243
Score = 175 bits (443), Expect = 7e-42, Method: Compositional matrix adjust.
Identities = 105/237 (45%), Positives = 132/237 (56%), Gaps = 9/237 (3%)
Query 2 HFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVT 61
WER+ V RCRLP D T GLV G +L++D G++ E + + + G +VT
Sbjct 7 ELGWERVAAGVGRCRLPVWDCTAGLVSGEDAVLVIDAGSSPAEGARLHEQARSLTGRRVT 66
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAI 119
H+ LTH HFDHV G++ F AEVF A L DR L DA+ G + A
Sbjct 67 HLALTHPHFDHVFGAAAFPDAEVFGAVGADAVLTRMRDRDELCADAVRNGLAASTAREAA 126
Query 120 AALKPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
L PP+H + + +DL G R V + + G GHT DL V+ P P VVF GDLV
Sbjct 127 DRLVPPRHLVSGEWTLDLGGGRQVLLANVGPGHTAHDLAVLVPGD-----PEVVFCGDLV 181
Query 178 EESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
EES +P D+ + WPA LDR+LA+GG DA YVPGHG VVDA FVR QR L R
Sbjct 182 EESGEPQAGPDAVPSQWPAALDRLLALGGEDALYVPGHGAVVDAAFVRAQRDALAAR 238
>gi|329934632|ref|ZP_08284673.1| putative metallo-beta-lactamase [Streptomyces griseoaurantiacus
M045]
gi|329305454|gb|EGG49310.1| putative metallo-beta-lactamase [Streptomyces griseoaurantiacus
M045]
Length=261
Score = 174 bits (441), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 114/261 (44%), Positives = 136/261 (53%), Gaps = 28/261 (10%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQ----- 59
WE +T V RCRLP D T GLV G LLVD G++L E + ADV ++ G
Sbjct 3 WEGVTARVGRCRLPRWDCTAGLVVGGEAALLVDAGSSLAEGARLRADVARLLGGHAGPAG 62
Query 60 ------------------VTHVVLTHKHFDHVLGSSVFDQAEVFCAPEV-VEYLRSATDR 100
VTH+ LTH HFDHV G+ F +AEVF A V Y
Sbjct 63 EAAHAGAGTGAGASGPRGVTHLALTHPHFDHVFGAPAFPEAEVFGAVGVDAAYTPRGRGE 122
Query 101 LREDALSYGADTAEVDRAIAALKPPQHGIY-DAAVDLGD-RTVTITHPGSGHTTADLVVV 158
LR DA+ G D A L PP+H + + +DLG TV + G GHT DL V+
Sbjct 123 LRADAVRNGLDPQAAAGAAGCLVPPRHHVTGEWTLDLGGGTTVLLADVGPGHTAHDLAVL 182
Query 159 APATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKV 218
PAT P VVF GDLVEES +P D+ A WPA LDR+L +GG DA YVPGHG +
Sbjct 183 VPAT--PSSPGVVFCGDLVEESGEPQAGPDAVPARWPAALDRLLGLGGEDAVYVPGHGAL 240
Query 219 VDAQFVRRQRAWLRTRASRQP 239
VDA+FVR QR L R P
Sbjct 241 VDARFVRAQRDALARRFGVSP 261
>gi|21221015|ref|NP_626794.1| hypothetical protein SCO2556 [Streptomyces coelicolor A3(2)]
gi|6714770|emb|CAB66234.1| conserved hypothetical protein SCC77.23 [Streptomyces coelicolor
A3(2)]
Length=247
Score = 170 bits (430), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 106/240 (45%), Positives = 134/240 (56%), Gaps = 13/240 (5%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
WERL D V RCRLP D T GLV G L+VD G++L E + +++AG +VTH
Sbjct 8 LGWERLADGVGRCRLPGWDCTAGLVLGADAALMVDAGSSLDEGARLREGARRLAGRRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLR------SATDRLREDALSYGADTAEVD 116
+ LTH HFDHV G++ F AEV+ A LR DA++ G D+
Sbjct 68 LALTHPHFDHVFGAAAFTGAEVYGAYGAAGTGALFAPGGQGRQALRADAVAEGLDSRAAR 127
Query 117 RAIAALKPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTG 174
A AL P +H + + +DL G R V + G GHT DL V+ P + P V+F G
Sbjct 128 EAAEALSPVRHEVRGEQPLDLGGGRRVLLADAGPGHTGHDLAVLVPGS-----PDVLFCG 182
Query 175 DLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
DLVEES +P D+ + WPA LDR+L +GG DA YVPGHG VVDA FVR QR L R
Sbjct 183 DLVEESGEPQAGPDAVPSHWPAALDRLLELGGDDALYVPGHGAVVDAAFVRVQRDALAAR 242
>gi|289771708|ref|ZP_06531086.1| metallo-beta-lactamase [Streptomyces lividans TK24]
gi|289701907|gb|EFD69336.1| metallo-beta-lactamase [Streptomyces lividans TK24]
Length=245
Score = 169 bits (427), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 105/240 (44%), Positives = 134/240 (56%), Gaps = 13/240 (5%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
WERL D V RCRLP D T GLV G L+VD G++L E + +++AG +VTH
Sbjct 6 LGWERLADGVGRCRLPGWDCTAGLVLGADAALMVDAGSSLDEGARLREGARRLAGRRVTH 65
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLR------SATDRLREDALSYGADTAEVD 116
+ LTH HFDHV G++ F AEV+ A LR DA++ G D+
Sbjct 66 LALTHPHFDHVFGAAAFTGAEVYGAYGAAGTGALFAPGGQGRQALRADAVAEGLDSRAAR 125
Query 117 RAIAALKPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTG 174
A A+ P +H + + +DL G R V + G GHT DL V+ P + P V+F G
Sbjct 126 EAAEAVSPVRHEVRGEQPLDLGGGRRVLLADAGPGHTGHDLAVLVPGS-----PDVLFCG 180
Query 175 DLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
DLVEES +P D+ + WPA LDR+L +GG DA YVPGHG VVDA FVR QR L R
Sbjct 181 DLVEESGEPQAGPDAVPSHWPAALDRLLELGGDDALYVPGHGAVVDAAFVRVQRDALAAR 240
>gi|29832111|ref|NP_826745.1| metallo-beta-lactamase [Streptomyces avermitilis MA-4680]
gi|29609229|dbj|BAC73280.1| putative metallo-beta-lactamase [Streptomyces avermitilis MA-4680]
Length=242
Score = 164 bits (414), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 100/234 (43%), Positives = 134/234 (58%), Gaps = 9/234 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGC--QVTH 62
WE + V R RLP D TVGLV G + L++D G++L E + A+ +++ G +VTH
Sbjct 10 WESVAPFVGRRRLPGWDCTVGLVIGDSAALMIDAGSSLREGALLRAEAQRLLGPGRRVTH 69
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
+ LTH HFDHV G++ F EVF A + L + LR DA+ G D + A L
Sbjct 70 LALTHPHFDHVFGAAAFSGVEVFGAVGLDTALAHGREELRADAVRNGLDPRAAEGAADLL 129
Query 123 KPPQHGIY-DAAVDLGDRT-VTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES 180
P+H ++ + +DLG V + + G GHT DL V+ ++ P VVF GDLVEES
Sbjct 130 VRPRHHVFGEWTLDLGGEVQVLLANVGPGHTAYDLAVLVSSS-----PEVVFCGDLVEES 184
Query 181 ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P D+ + WPA LDR+L +GG DA YVPGHG VDA FVR QR L R
Sbjct 185 GEPQAGPDAIPSHWPAALDRLLDLGGQDAVYVPGHGATVDAAFVRTQRDELAAR 238
>gi|290960534|ref|YP_003491716.1| hypothetical protein SCAB_61541 [Streptomyces scabiei 87.22]
gi|260650060|emb|CBG73176.1| conserved hypothetical protein [Streptomyces scabiei 87.22]
Length=243
Score = 162 bits (410), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 102/233 (44%), Positives = 131/233 (57%), Gaps = 7/233 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADV-KQIAGCQVTHV 63
W+ LT V RCRLP D T GLV G L++D G++L E + A+ + + G +VTH+
Sbjct 10 WQELTPGVGRCRLPGWDCTAGLVVGDGAALVIDAGSSLREGARLRAEACRLLGGARVTHL 69
Query 64 VLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALK 123
LTH HFDHV G++ F EVF A V L + LR DA+ +G A+ A L
Sbjct 70 ALTHPHFDHVFGAAAFAGVEVFGAVGVDGVLGRDHEALRADAVHHGLPAADATEAADLLV 129
Query 124 PPQHGIY-DAAVDLGDRT-VTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESA 181
P+H + + +DLG V + + G GHT DL V+ VVF GDLVEES
Sbjct 130 RPRHLVSGEWTLDLGGEVRVLLANVGPGHTGHDLAVLVSGGAR----EVVFCGDLVEESG 185
Query 182 DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P D+ + WPA LDR+L +GG DA YVPGHG VVDA FVR QR L R
Sbjct 186 EPQAGPDAIPSRWPAALDRLLDLGGEDALYVPGHGAVVDAAFVRAQRDALARR 238
>gi|254382704|ref|ZP_04998061.1| metallo-beta-lactamase [Streptomyces sp. Mg1]
gi|194341606|gb|EDX22572.1| metallo-beta-lactamase [Streptomyces sp. Mg1]
Length=241
Score = 160 bits (406), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 107/231 (47%), Positives = 131/231 (57%), Gaps = 6/231 (2%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WERLT R RLP D TVGLV G +LLVD G+ + E + A+ +++ G +VTH+
Sbjct 10 WERLTGRTGRRRLPVWDCTVGLVVGDDSVLLVDPGSCVREGAEVRAEAERLTGRRVTHIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
TH HFDHVLG + F AE F A + L D LR DA+ +G AE A L
Sbjct 70 FTHGHFDHVLGGAAFSGAEFFGAVGLDALLTVGRDELRGDAVRHGLAEAEAAEAADLLAA 129
Query 125 PQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADP 183
P+H + + +DLG V + + G GHT DL V P VVF GDLVEES DP
Sbjct 130 PKHLVSGEWTLDLGGVQVLLANVGPGHTRHDLAVFVPGV-----REVVFCGDLVEESGDP 184
Query 184 DIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
D+ WPA LDR+L++GG DA YVPGHG VV A FVR QR LR R
Sbjct 185 SAGPDAVPRQWPAALDRLLSLGGDDALYVPGHGAVVGAAFVRAQRDTLRAR 235
>gi|302519003|ref|ZP_07271345.1| metallo-beta-lactamase [Streptomyces sp. SPB78]
gi|318061220|ref|ZP_07979941.1| hypothetical protein SSA3_24974 [Streptomyces sp. SA3_actG]
gi|318076110|ref|ZP_07983442.1| hypothetical protein SSA3_05183 [Streptomyces sp. SA3_actF]
gi|302427898|gb|EFK99713.1| metallo-beta-lactamase [Streptomyces sp. SPB78]
Length=242
Score = 157 bits (397), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 112/237 (48%), Positives = 136/237 (58%), Gaps = 12/237 (5%)
Query 4 DWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTL--GEATAIAADVKQIAGCQVT 61
+WE V R RLP D T GLVRG LLVD G L GEA AA+ G +VT
Sbjct 8 EWEHPAPGVARLRLPGWDCTAGLVRGEDAALLVDPGAGLAQGEAVRRAAERLLGDGSRVT 67
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAI 119
H+ LTH HFDHVLG+ +A V+ A L + R LREDA+ +G D AE RA
Sbjct 68 HLALTHPHFDHVLGAPAV-EAPVYAAVGSESLLGTEAGRAELREDAVRHGLDPAEARRAA 126
Query 120 AALKPPQHGIY-DAAVDLGD-RTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
A L+ P + + A+DLG R V + + G GH+ DLV+V P TVVF GDLV
Sbjct 127 ALLRGPDQPVSGEFALDLGGGRRVLLANVGPGHSGHDLVLVVPGE-----RTVVFCGDLV 181
Query 178 EESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
EES +P D+ A WP LDR+L +GG +A YVPGHG +VDA FVRRQR L R
Sbjct 182 EESGEPQAGPDAVPARWPEALDRLLGLGGDEAVYVPGHGALVDAAFVRRQRDALARR 238
>gi|333027166|ref|ZP_08455230.1| putative metallo-beta-lactamase [Streptomyces sp. Tu6071]
gi|332747018|gb|EGJ77459.1| putative metallo-beta-lactamase [Streptomyces sp. Tu6071]
Length=242
Score = 156 bits (395), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 111/237 (47%), Positives = 135/237 (57%), Gaps = 12/237 (5%)
Query 4 DWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTL--GEATAIAADVKQIAGCQVT 61
+WE V R RLP D T GLVRG LLVD G L GEA AA+ G +VT
Sbjct 8 EWEHPAPGVARLRLPGWDCTAGLVRGEDAALLVDPGAGLAQGEAVRRAAERLLGDGSRVT 67
Query 62 HVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAI 119
H+ LTH HFDH LG+ +A V+ A L + R LREDA+ +G D AE RA
Sbjct 68 HLALTHPHFDHALGAPAV-EAPVYAAVGAESLLGTEAGRAELREDAVRHGLDPAEARRAA 126
Query 120 AALKPPQHGIY-DAAVDLGD-RTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
A L+ P + + A+DLG R V + + G GH+ DLV+V P TVVF GDLV
Sbjct 127 ALLRGPDQPVSGEFALDLGGGRRVLLANVGPGHSGHDLVLVVPGE-----RTVVFCGDLV 181
Query 178 EESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
EES +P D+ A WP LDR+L +GG +A YVPGHG +VDA FVRRQR L R
Sbjct 182 EESGEPQAGPDAVPARWPGALDRLLGLGGDEAVYVPGHGALVDAAFVRRQRDTLARR 238
>gi|291451261|ref|ZP_06590651.1| metallo-beta-lactamase [Streptomyces albus J1074]
gi|291354210|gb|EFE81112.1| metallo-beta-lactamase [Streptomyces albus J1074]
Length=246
Score = 154 bits (389), Expect = 1e-35, Method: Compositional matrix adjust.
Identities = 107/239 (45%), Positives = 132/239 (56%), Gaps = 13/239 (5%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQI-----AG 57
+ WE V R RLP D T GL G G LL+D G +L E + +Q
Sbjct 10 WRWEWPAPGVGRLRLPRWDATAGLAVGPAGALLIDAGASLREGALLRHAAEQALRERGGP 69
Query 58 CQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDR 117
+VTH+ LTH HFDHV G++ F AEV A + L + T L DA+ +G E
Sbjct 70 RRVTHLALTHAHFDHVFGAAAFAGAEVHGAVGLDTAL-TRTGTLESDAVRHGLGPREAGE 128
Query 118 AIAALKPPQHGIY-DAAVDLG-DRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGD 175
A AL P+H + +A V+LG +R V + + G GHT DL V+ P T P VVF GD
Sbjct 129 AADALVVPRHLVSGEAVVELGGERRVLLANLGPGHTAHDLAVLVPGT-----PDVVFCGD 183
Query 176 LVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
LVEES +P D+ A WP LDR+LA+GGPDA YVPGHG VVDA FVR QR L R
Sbjct 184 LVEESGEPQAGPDALPARWPEALDRLLALGGPDAVYVPGHGAVVDAAFVRAQRHELARR 242
>gi|302534344|ref|ZP_07286686.1| metallo-beta-lactamase [Streptomyces sp. C]
gi|302443239|gb|EFL15055.1| metallo-beta-lactamase [Streptomyces sp. C]
Length=243
Score = 154 bits (388), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 99/233 (43%), Positives = 134/233 (58%), Gaps = 8/233 (3%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
WER+T V R RLP D TVGLV G +LL+D G+++ E + A+ +++ G +VTH+
Sbjct 10 WERVTGRVGRRRLPVWDCTVGLVVGDESMLLIDPGSSVREGAQVRAEAERLTGRRVTHIA 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDR--LREDALSYGADTAEVDRAIAAL 122
TH HFDHVLG + F AE F A + L + T R +R A+ G E A L
Sbjct 70 FTHGHFDHVLGGAAFAGAEFFGAVGLERLLSAPTGREEVRMSAVLQGLAEEEAAEAADLL 129
Query 123 KPPQHGIY-DAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESA 181
+ P+H + + ++LG V + + G H+ DL V P A VF GDLVEES
Sbjct 130 QAPRHLVSGEWTLELGGVQVLLANVGPAHSEHDLAVFVPGEREA-----VFCGDLVEESG 184
Query 182 DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
+P +D+ WPA LDR+L++GG DA YVPGHG +VDA+FVR QR L R
Sbjct 185 EPQAGSDAVPGQWPAALDRLLSLGGDDAVYVPGHGALVDAEFVRAQRDTLAAR 237
>gi|182438785|ref|YP_001826504.1| putative metallo-beta-lactamase [Streptomyces griseus subsp.
griseus NBRC 13350]
gi|178467301|dbj|BAG21821.1| putative metallo-beta-lactamase [Streptomyces griseus subsp.
griseus NBRC 13350]
Length=242
Score = 153 bits (386), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 104/235 (45%), Positives = 131/235 (56%), Gaps = 6/235 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
F WERL V R RLP D TV LV G G+LL DTG+TL E + + + G +VTH
Sbjct 8 FGWERLGRGVGRRRLPGWDATVALVAGAEGVLLYDTGSTLREGVELRRQAEALLGRRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
+ L+H HFDHVLG++ F V + + LR L DA+ +G E R+ L
Sbjct 68 IALSHPHFDHVLGTAAFAGVRVHGSAGLTALLRDGEQALHGDAVRHGVPEDEAARSADTL 127
Query 123 KPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADG-PTVVFTGDLVEE 179
P + + +DL G R V + G H++ DL V+ P + DG P VV GDLVEE
Sbjct 128 VVPHEEVRGERTLDLGGGRRVLLADLGPAHSSHDLAVLVPGS---DGEPPVVLCGDLVEE 184
Query 180 SADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
S +P D+ A WPA L R+L +GG DA YVPGHG VVDA FVR QRA L R
Sbjct 185 SGEPQAGPDAVPARWPAALGRLLELGGEDALYVPGHGAVVDAAFVRAQRAALAER 239
>gi|326779440|ref|ZP_08238705.1| beta-lactamase domain protein [Streptomyces cf. griseus XylebKG-1]
gi|326659773|gb|EGE44619.1| beta-lactamase domain protein [Streptomyces griseus XylebKG-1]
Length=242
Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 104/235 (45%), Positives = 131/235 (56%), Gaps = 6/235 (2%)
Query 3 FDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTH 62
F WERL V R RLP D TV LV G G+LL DTG+TL E + + + G +VTH
Sbjct 8 FGWERLGRGVGRRRLPGWDATVALVAGAEGVLLYDTGSTLREGVELRRQAEALLGRRVTH 67
Query 63 VVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAAL 122
+ L+H HFDHVLG++ F V + + LR L DA+ +G E R+ L
Sbjct 68 IALSHPHFDHVLGTAAFAGVRVHGSAGLTALLRDGEQALYGDAVRHGVPEDEAARSADTL 127
Query 123 KPPQHGIY-DAAVDL-GDRTVTITHPGSGHTTADLVVVAPATGHADG-PTVVFTGDLVEE 179
P + + +DL G R V + G H++ DL V+ P + DG P VV GDLVEE
Sbjct 128 VVPHEEVRGERTLDLGGGRRVLLADLGPAHSSHDLAVLVPGS---DGEPPVVLCGDLVEE 184
Query 180 SADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTR 234
S +P D+ A WPA L R+L +GG DA YVPGHG VVDA FVR QRA L R
Sbjct 185 SGEPQAGPDAVPARWPAALGRLLELGGEDALYVPGHGAVVDAAFVRAQRAALAER 239
>gi|317125974|ref|YP_004100086.1| beta-lactamase [Intrasporangium calvum DSM 43043]
gi|315590062|gb|ADU49359.1| beta-lactamase domain protein [Intrasporangium calvum DSM 43043]
Length=311
Score = 123 bits (309), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 86/234 (37%), Positives = 115/234 (50%), Gaps = 16/234 (6%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAG-CQVTHV 63
+ + D V R P DV VGL+ GR G ++VDT +L + + D++++ +V HV
Sbjct 5 FREVADRVFVARYPQWDVNVGLILGRDGAVVVDTRASLLQGFGVLDDIRRLGSDIEVRHV 64
Query 64 VLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLRE-------DALSYGADTAEVD 116
V TH HFDH G+ F A V V + R++ D G + +V
Sbjct 65 VNTHVHFDHTFGNGAFTAATVHAHANVARSVEGDAARIKNLFRADPGDHPQAGYTSRDVV 124
Query 117 RAIA-ALKPPQHGI-YDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTG 174
A A++PP + A +DLGDR VT++ G GHT D+ V H D +F G
Sbjct 125 EVCATAVRPPDRTFEHSATIDLGDRAVTMSWAGRGHTDGDISV------HVDDAGAMFLG 178
Query 175 DLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQR 228
DLVEESA P ADS W TL L + VPGHG VD +FVRRQR
Sbjct 179 DLVEESAPPAFGADSWPLEWADTLGEHLGWLDLSSVVVPGHGTPVDTEFVRRQR 232
>gi|134097934|ref|YP_001103595.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
gi|291009154|ref|ZP_06567127.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
gi|133910557|emb|CAM00670.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
Length=263
Score = 120 bits (301), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 89/230 (39%), Positives = 118/230 (52%), Gaps = 17/230 (7%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
W+ + D V R D+TVGLV G L+VDT + +A V+Q+ VV
Sbjct 4 WQEVGDGVLVRRYAELDLTVGLVVGSELALVVDTRGDHRQGAELAEAVRQVTPLP-WQVV 62
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA---- 120
LTH HFDH G+ F A V+ +L + R + +++ + D A A
Sbjct 63 LTHAHFDHCFGTGAFLPAPVWAHERCARHLDRTGESQRAEWIAHYREQGREDIADALAET 122
Query 121 ALKPPQHGIYDAA-VDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEE 179
+ P H + DAA +DLG RT + H G GHT DLV+ A VVF GDLVE+
Sbjct 123 TITGPDHLVADAAEIDLGGRTTRLLHLGPGHTDHDLVIAA--------GDVVFAGDLVEQ 174
Query 180 SADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRA 229
A PD D+ WP+TLD +LA+ A+ VPGHG+ VD FVRRQRA
Sbjct 175 GAPPDF-GDAHPRHWPSTLDALLAL--TPATVVPGHGEPVDPDFVRRQRA 221
>gi|284030353|ref|YP_003380284.1| beta-lactamase domain-containing protein [Kribbella flavida DSM
17836]
gi|283809646|gb|ADB31485.1| beta-lactamase domain protein [Kribbella flavida DSM 17836]
Length=296
Score = 114 bits (286), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 95/247 (39%), Positives = 123/247 (50%), Gaps = 24/247 (9%)
Query 4 DWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHV 63
+W L D R DV VGLV G G L+VDT + +AT + A+++++ V V
Sbjct 3 EWTELGDRCWVRRYREWDVNVGLVVGSEGALVVDTRASTAQATELLAEIRELTDAPVRWV 62
Query 64 VLTHKHFDHVLGSSVFDQAEVFC-----------APEVVEYLRSATDRLREDALSYGADT 112
V TH HFDH G+ VF +A + P + ++ R+A +Y
Sbjct 63 VNTHAHFDHTFGNGVFTEAARYAHENAAAALAERGPALQQHYRAAPG----PDPAYPDIP 118
Query 113 AEVDRAIAA--LKPPQHGIYDAAV-DLGDRTVTITHPGSGHTTADLVVVAPATGHADGPT 169
AEV +AA L H A V LGDR V + H G+ HT D+VVV P
Sbjct 119 AEVLAEVAATGLVAIDHTFAVAKVIGLGDRRVELLHLGNAHTDGDVVVVVPDA------D 172
Query 170 VVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRA 229
V F GDLVE+SA P DS WP TLDRV+ + G ++ VPGHG VVDA FVR Q
Sbjct 173 VYFVGDLVEQSAPPSFGDDSYPLEWPETLDRVIGLLGTESKVVPGHGAVVDADFVRDQAG 232
Query 230 WLRTRAS 236
L T A+
Sbjct 233 DLGTVAN 239
>gi|291299170|ref|YP_003510448.1| beta-lactamase domain-containing protein [Stackebrandtia nassauensis
DSM 44728]
gi|290568390|gb|ADD41355.1| beta-lactamase domain protein [Stackebrandtia nassauensis DSM
44728]
Length=238
Score = 114 bits (285), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 87/243 (36%), Positives = 117/243 (49%), Gaps = 42/243 (17%)
Query 4 DWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHV 63
D++R+ D VH R P DV LV GR LLVDT +T G+A +AA V+++ V V
Sbjct 13 DFQRVADDVHVLRYPVLDVNCVLVLGRDRALLVDTLSTAGQARELAAAVRRLTSSPVV-V 71
Query 64 VLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRA----- 118
V TH HFDH G+ + E L + E A++ AD AE A
Sbjct 72 VNTHDHFDHWFGNHT-----------IAEQLGAVDFWAHESAIAVDADHAESRAAARRAC 120
Query 119 -------------IAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHA 165
+ L P + +A +DLG R+V + HPG H+ DL+ A
Sbjct 121 VKLAPEIADEVGDLELLTPNRPVTDEATIDLGGRSVRLWHPGRAHSHGDLIAFA------ 174
Query 166 DGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVL-AIGGPDASYVPGHGKVVDAQFV 224
+V GDLVEE A P + +D+D A W L+R+ I GP +PGHG +VDA FV
Sbjct 175 --GSVTIAGDLVEEGAPPSVGSDADAAHWSRVLERLAPMIEGP---VIPGHGAIVDAAFV 229
Query 225 RRQ 227
RQ
Sbjct 230 TRQ 232
>gi|119716134|ref|YP_923099.1| beta-lactamase domain-containing protein [Nocardioides sp. JS614]
gi|119536795|gb|ABL81412.1| beta-lactamase domain protein [Nocardioides sp. JS614]
Length=287
Score = 112 bits (279), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 85/235 (37%), Positives = 113/235 (49%), Gaps = 18/235 (7%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
+ + D V R + DV V LV G +G+L+VDT + A A+ D++++ V VV
Sbjct 3 FREVADRVWVARYEWFDVNVTLVGGDSGLLVVDTHASATAARAVVDDIRRLGAGTVIAVV 62
Query 65 LTHKHFDHVLGSSVFDQA-----EVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAI 119
TH+HFDH G+ A + E A +R++ A D + +
Sbjct 63 NTHEHFDHTFGNGELRSAYGADLPIHAHEAAAERTVPAGERIQA-AYDEEPDDPHREEVL 121
Query 120 AALKPPQHGIYDAA--VDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLV 177
A P + +A +DLGDR V + HPG GHT DLVV P AD V+ GDLV
Sbjct 122 ATTIVPADRTFSSARVLDLGDRMVELVHPGRGHTAGDLVVRVP---DAD---VLLAGDLV 175
Query 178 EESA----DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQR 228
EESA P D WP +LD VL + PD+ VPGHG VD FV QR
Sbjct 176 EESALRAGVPGFGEDCYPFDWPLSLDVVLTLTTPDSVVVPGHGAPVDRDFVEEQR 230
>gi|313837298|gb|EFS75012.1| metallo-beta-lactamase domain protein [Propionibacterium acnes
HL037PA2]
gi|314971794|gb|EFT15892.1| metallo-beta-lactamase domain protein [Propionibacterium acnes
HL037PA3]
Length=227
Score = 108 bits (270), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 80/241 (34%), Positives = 111/241 (47%), Gaps = 34/241 (14%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
W LT V + VT GLV G +LL+DTG+T + ++A + G V +V
Sbjct 10 WSALTTRVWTTTVEPESVTCGLVAGEDHVLLIDTGSTPEQGHSLAMSAVCMLGRPVDRIV 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
+TH H+DH G S + AEV+ + E AL++ D VD ++ +
Sbjct 70 VTHHHYDHSGGLSGINDAEVW---------------MHEAALAHCPDL-HVDHPVSLM-- 111
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPD 184
A VDLG + HPG HT DL+V+ + F GDLVE + +P
Sbjct 112 -------AYVDLGGLGAEVIHPGPAHTDGDLIVIV------RDEKITFAGDLVETAGEPQ 158
Query 185 IDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPA 244
D +D+ WP +D V+ + YVPGHG +DA V QRA L A R P P
Sbjct 159 SDETTDVRGWPRAIDSVITGTDGASLYVPGHGHPIDATTVMNQRARL---AERVPMNIPL 215
Query 245 T 245
T
Sbjct 216 T 216
>gi|314928028|gb|EFS91859.1| metallo-beta-lactamase domain protein [Propionibacterium acnes
HL044PA1]
Length=227
Score = 107 bits (268), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 80/241 (34%), Positives = 110/241 (46%), Gaps = 34/241 (14%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
W LT V + VT GLV G +LL+DTG+T + ++A + G V +V
Sbjct 10 WSALTTRVWTTTVEPESVTCGLVAGEDHVLLIDTGSTPEQGHSLAMSAVCMLGRPVDRIV 69
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
+TH H+DH G S + AEV+ + E AL++ D VD ++ +
Sbjct 70 VTHHHYDHSGGLSGINDAEVW---------------MHEAALAHCPDL-HVDHPVSLM-- 111
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPD 184
A VDLG + HPG HT DL+V+ + F GDLVE + +P
Sbjct 112 -------AYVDLGGLGAEVIHPGPAHTDGDLIVIV------RDEKITFAGDLVETAGEPQ 158
Query 185 IDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPA 244
D +D+ WP +D V+ YVPGHG +DA V QRA L A R P P
Sbjct 159 SDETTDVRGWPRAIDSVITGTDGAGLYVPGHGHPIDATTVMNQRARL---AERVPMNIPL 215
Query 245 T 245
T
Sbjct 216 T 216
>gi|328907153|gb|EGG26919.1| metallo-beta-lactamase domain protein [Propionibacterium humerusii
P08]
Length=229
Score = 107 bits (268), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 80/241 (34%), Positives = 110/241 (46%), Gaps = 34/241 (14%)
Query 5 WERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVV 64
W LT V + VT GLV G +LL+DTG+T + ++A + G V +V
Sbjct 12 WSALTTRVWTTTVEPESVTCGLVAGEDHVLLIDTGSTPEQGHSLAMSAVCMLGRPVDRIV 71
Query 65 LTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKP 124
+TH H+DH G S + AEV+ + E AL++ D VD ++ +
Sbjct 72 VTHHHYDHSGGLSGINDAEVW---------------MHEAALAHCPDL-HVDHPVSLM-- 113
Query 125 PQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPD 184
A VDLG + HPG HT DL+V+ + F GDLVE + +P
Sbjct 114 -------AYVDLGGLGAEVIHPGPAHTDGDLIVIV------RDEKITFAGDLVETAGEPQ 160
Query 185 IDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPA 244
D +D+ WP +D V+ YVPGHG +DA V QRA L A R P P
Sbjct 161 SDETTDVRGWPRAIDSVITGTDGAGLYVPGHGHPIDATTVMNQRARL---AERVPMNIPL 217
Query 245 T 245
T
Sbjct 218 T 218
Lambda K H
0.320 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 358945203960
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40