BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1915
Length=367
Score E
Sequences producing significant alignments: (Bits) Value
gi|15609052|ref|NP_216431.1| isocitrate lyase [Mycobacterium tub... 749 0.0
gi|306779921|ref|ZP_07418258.1| isocitrate lyase aceAa [Mycobact... 747 0.0
gi|31793108|ref|NP_855601.1| isocitrate lyase [Mycobacterium bov... 609 2e-172
gi|289750497|ref|ZP_06509875.1| LOW QUALITY PROTEIN: isocitrate ... 607 1e-171
gi|294996827|ref|ZP_06802518.1| isocitrate lyase [Mycobacterium ... 607 1e-171
gi|240172596|ref|ZP_04751255.1| isocitrate lyase AceAb [Mycobact... 563 2e-158
gi|183982825|ref|YP_001851116.1| isocitrate lyase AceAb [Mycobac... 555 4e-156
gi|118618351|ref|YP_906683.1| isocitrate lyase AceAb [Mycobacter... 552 3e-155
gi|296164945|ref|ZP_06847501.1| isocitrate lyase [Mycobacterium ... 535 3e-150
gi|15828074|ref|NP_302337.1| isocitrate lyase [Mycobacterium lep... 531 5e-149
gi|13637587|sp|P46831.2|ACEA_MYCLE RecName: Full=Isocitrate lyas... 528 4e-148
gi|41407741|ref|NP_960577.1| isocitrate lyase [Mycobacterium avi... 526 2e-147
gi|559906|emb|CAA86357.1| isocitrate lyase [Mycobacterium leprae] 526 3e-147
gi|118464681|ref|YP_881969.1| isocitrate lyase [Mycobacterium av... 526 3e-147
gi|254821861|ref|ZP_05226862.1| isocitrate lyase [Mycobacterium ... 525 7e-147
gi|333990644|ref|YP_004523258.1| isocitrate lyase AceAb [Mycobac... 519 3e-145
gi|342859571|ref|ZP_08716224.1| isocitrate lyase [Mycobacterium ... 519 3e-145
gi|120403959|ref|YP_953788.1| isocitrate lyase [Mycobacterium va... 509 3e-142
gi|145223847|ref|YP_001134525.1| isocitrate lyase [Mycobacterium... 508 6e-142
gi|315444176|ref|YP_004077055.1| isocitrate lyase [Mycobacterium... 508 6e-142
gi|126432789|ref|YP_001068480.1| isocitrate lyase [Mycobacterium... 501 7e-140
gi|108797167|ref|YP_637364.1| isocitrate lyase [Mycobacterium sp... 501 8e-140
gi|118471001|ref|YP_888007.1| isocitrate lyase [Mycobacterium sm... 500 1e-139
gi|197122060|ref|YP_002134011.1| isocitrate lyase [Anaeromyxobac... 449 2e-124
gi|220916830|ref|YP_002492134.1| isocitrate lyase [Anaeromyxobac... 447 1e-123
gi|86158643|ref|YP_465428.1| isocitrate lyase [Anaeromyxobacter ... 446 3e-123
gi|153004450|ref|YP_001378775.1| isocitrate lyase [Anaeromyxobac... 437 2e-120
gi|328856720|gb|EGG05840.1| hypothetical protein MELLADRAFT_4870... 239 5e-61
gi|301111828|ref|XP_002904993.1| isocitrate lyase [Phytophthora ... 238 1e-60
gi|164656513|ref|XP_001729384.1| hypothetical protein MGL_3419 [... 235 7e-60
gi|331218780|ref|XP_003322067.1| isocitrate lyase [Puccinia gram... 231 1e-58
gi|336370073|gb|EGN98414.1| hypothetical protein SERLA73DRAFT_55... 228 1e-57
gi|302689573|ref|XP_003034466.1| isocitrate lyase [Schizophyllum... 226 4e-57
gi|71020403|ref|XP_760432.1| hypothetical protein UM04285.1 [Ust... 224 3e-56
gi|325188195|emb|CCA22736.1| isocitrate lyase putative [Albugo l... 223 4e-56
gi|343425324|emb|CBQ68860.1| probable isocitrate lyase [Sporisor... 221 2e-55
gi|298706764|emb|CBJ29687.1| Isocitrate lyase (Isocitrase) (Isoc... 217 2e-54
gi|170089369|ref|XP_001875907.1| isocitrate lyase icl [Laccaria ... 217 2e-54
gi|340914878|gb|EGS18219.1| isocitrate lyase-like protein [Chaet... 216 6e-54
gi|8134297|sp|O13439.1|ACEA_COPCI RecName: Full=Isocitrate lyase... 216 7e-54
gi|169858104|ref|XP_001835698.1| isocitrate lyase [Coprinopsis c... 215 8e-54
gi|145843726|gb|ABP96877.1| isocitrate lyase [Tuber borchii] 215 1e-53
gi|328766513|gb|EGF76567.1| hypothetical protein BATDEDRAFT_1806... 215 1e-53
gi|62122373|dbj|BAD93181.1| isocitrate lyase [Fomitopsis palustris] 214 1e-53
gi|54035734|sp|Q9HFN2.1|ACEA_PICJA RecName: Full=Isocitrate lyas... 214 2e-53
gi|13123962|sp|Q9P8Q7.1|ACEA_CANAL RecName: Full=Isocitrate lyas... 214 2e-53
gi|294881042|ref|XP_002769215.1| Isocitrate lyase, putative [Per... 214 2e-53
gi|68487782|ref|XP_712232.1| hypothetical protein CaO19.6844 [Ca... 214 3e-53
gi|241948743|ref|XP_002417094.1| isocitrate lyase, putative [Can... 214 3e-53
gi|146413757|ref|XP_001482849.1| isocitrate lyase [Meyerozyma gu... 213 5e-53
>gi|15609052|ref|NP_216431.1| isocitrate lyase [Mycobacterium tuberculosis H37Rv]
gi|148661723|ref|YP_001283246.1| isocitrate lyase AceAa [Mycobacterium tuberculosis H37Ra]
gi|148823127|ref|YP_001287881.1| isocitrate lyase aceAa [Mycobacterium tuberculosis F11]
18 more sequence titles
Length=367
Score = 749 bits (1933), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 367/367 (100%), Positives = 367/367 (100%), Gaps = 0/367 (0%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA
Sbjct 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP
Sbjct 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
Query 301 RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR 360
RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR
Sbjct 301 RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR 360
Query 361 PGRTTRA 367
PGRTTRA
Sbjct 361 PGRTTRA 367
>gi|306779921|ref|ZP_07418258.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu002]
gi|306803626|ref|ZP_07440294.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu008]
gi|306808200|ref|ZP_07444868.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu007]
gi|306968015|ref|ZP_07480676.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu009]
gi|308327181|gb|EFP16032.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu002]
gi|308345432|gb|EFP34283.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu007]
gi|308349735|gb|EFP38586.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu008]
gi|308354374|gb|EFP43225.1| isocitrate lyase aceAa [Mycobacterium tuberculosis SUMu009]
Length=367
Score = 747 bits (1928), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 366/367 (99%), Positives = 366/367 (99%), Gaps = 0/367 (0%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDT VHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA
Sbjct 1 MAIAETDTAVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP
Sbjct 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
Query 301 RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR 360
RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR
Sbjct 301 RSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWR 360
Query 361 PGRTTRA 367
PGRTTRA
Sbjct 361 PGRTTRA 367
>gi|31793108|ref|NP_855601.1| isocitrate lyase [Mycobacterium bovis AF2122/97]
gi|50953770|ref|NP_336424.2| isocitrate lyase [Mycobacterium tuberculosis CDC1551]
gi|121637821|ref|YP_978044.1| putative isocitrate lyase aceA [Mycobacterium bovis BCG str.
Pasteur 1173P2]
28 more sequence titles
Length=766
Score = 609 bits (1571), Expect = 2e-172, Method: Compositional matrix adjust.
Identities = 302/339 (90%), Positives = 312/339 (93%), Gaps = 8/339 (2%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA
Sbjct 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP
Sbjct 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADA T
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGV 300
Query 301 R--SSMVIFSM---RLATAS---TRRPAVGLSAKAFSAW 331
+ + +++++ A A R+ GL + A +AW
Sbjct 301 KELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAW 339
>gi|289750497|ref|ZP_06509875.1| LOW QUALITY PROTEIN: isocitrate lyase aceAa [Mycobacterium tuberculosis
T92]
gi|289758021|ref|ZP_06517399.1| LOW QUALITY PROTEIN: isocitrate lyase [Mycobacterium tuberculosis
T85]
gi|339631968|ref|YP_004723610.1| isocitrate lyase [Mycobacterium africanum GM041182]
gi|340626924|ref|YP_004745376.1| putative isocitrate lyase ACEAA (first part) [Mycobacterium canettii
CIPT 140010059]
gi|289691084|gb|EFD58513.1| LOW QUALITY PROTEIN: isocitrate lyase aceAa [Mycobacterium tuberculosis
T92]
gi|289713585|gb|EFD77597.1| LOW QUALITY PROTEIN: isocitrate lyase [Mycobacterium tuberculosis
T85]
gi|339331324|emb|CCC27008.1| putative isocitrate lyase ACEAA [first part] (isocitrase) [Mycobacterium
africanum GM041182]
gi|340005114|emb|CCC44263.1| putative isocitrate lyase ACEAA [first part] (isocitrase) (isocitratase)
(ICL) [Mycobacterium canettii CIPT 140010059]
Length=368
Score = 607 bits (1565), Expect = 1e-171, Method: Compositional matrix adjust.
Identities = 302/339 (90%), Positives = 312/339 (93%), Gaps = 8/339 (2%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA
Sbjct 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP
Sbjct 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADA T
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGV 300
Query 301 R--SSMVIFSM---RLATAS---TRRPAVGLSAKAFSAW 331
+ + +++++ A A R+ GL + A +AW
Sbjct 301 KELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAW 339
>gi|294996827|ref|ZP_06802518.1| isocitrate lyase [Mycobacterium tuberculosis 210]
Length=506
Score = 607 bits (1564), Expect = 1e-171, Method: Compositional matrix adjust.
Identities = 302/339 (90%), Positives = 312/339 (93%), Gaps = 8/339 (2%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA
Sbjct 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP
Sbjct 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADA T
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGV 300
Query 301 R--SSMVIFSM---RLATAS---TRRPAVGLSAKAFSAW 331
+ + +++++ A A R+ GL + A +AW
Sbjct 301 KELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAW 339
>gi|240172596|ref|ZP_04751255.1| isocitrate lyase AceAb [Mycobacterium kansasii ATCC 12478]
Length=766
Score = 563 bits (1450), Expect = 2e-158, Method: Compositional matrix adjust.
Identities = 274/339 (81%), Positives = 299/339 (89%), Gaps = 8/339 (2%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDT V TPFEQDF+K+ A TQRYFDS+RFAGIIRLYTARQVVEQRGTIPVD+ VA
Sbjct 1 MAIAETDTAVRTPFEQDFDKETAETQRYFDSARFAGIIRLYTARQVVEQRGTIPVDYTVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R AA AFYERLRELFAA KSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGS+TEDP
Sbjct 61 RTAAAAFYERLRELFAANKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSTTEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ YLRL M+E+QRAA P YDFRPFIIADA T
Sbjct 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLNMTEQQRAAAPVYDFRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNL+RRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 181 GHGGDPHVRNLVRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
D+M VPGIIVARTDAEAANLIDSRADERDQPFLLGAT L++PSYK+CFLAM+RRF
Sbjct 241 DVMGVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLNIPSYKACFLAMLRRFHELGV 300
Query 301 R--SSMVIFSM---RLATAST---RRPAVGLSAKAFSAW 331
+ + +++++ ATA+ R+ +G+ A + W
Sbjct 301 KELNGHLLYALAEGEYATATAWLERQGIMGVITDAVNTW 339
>gi|183982825|ref|YP_001851116.1| isocitrate lyase AceAb [Mycobacterium marinum M]
gi|183176151|gb|ACC41261.1| isocitrate lyase AceAb [Mycobacterium marinum M]
Length=762
Score = 555 bits (1431), Expect = 4e-156, Method: Compositional matrix adjust.
Identities = 267/295 (91%), Positives = 281/295 (96%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAIAETDTEV TPFEQ+ VA TQRYFDSSRFAGI+RLYTARQVVEQRGTIP D+ VA
Sbjct 1 MAIAETDTEVRTPFEQE----VADTQRYFDSSRFAGIVRLYTARQVVEQRGTIPNDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R AAGAFY+RLREL+A +KS+TTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGS+TEDP
Sbjct 57 RTAAGAFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ YLRLQM+++QRA T AYDFRPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRATTTAYDFRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
D+MRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLD+PSYKSCFLAM+RRF
Sbjct 237 DVMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDIPSYKSCFLAMLRRF 291
>gi|118618351|ref|YP_906683.1| isocitrate lyase AceAb [Mycobacterium ulcerans Agy99]
gi|118570461|gb|ABL05212.1| isocitrate lyase AceAb [Mycobacterium ulcerans Agy99]
Length=762
Score = 552 bits (1422), Expect = 3e-155, Method: Compositional matrix adjust.
Identities = 264/295 (90%), Positives = 279/295 (95%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI ETDTE+ TPFEQ+ VA TQRYFDSSRFAGI+RLYTARQVVEQRGTIP D+ VA
Sbjct 1 MAIVETDTEIRTPFEQE----VADTQRYFDSSRFAGIVRLYTARQVVEQRGTIPNDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R AAG FY+RLREL+A +KS+TTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGS+TEDP
Sbjct 57 RTAAGVFYQRLRELYAEKKSVTTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ YLRLQM+++QRA T AYDFRPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQEYLRLQMTDQQRATTTAYDFRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
D+MRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLD+PSYKSCFLAM+RRF
Sbjct 237 DVMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDIPSYKSCFLAMLRRF 291
>gi|296164945|ref|ZP_06847501.1| isocitrate lyase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295899787|gb|EFG79237.1| isocitrate lyase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=763
Score = 535 bits (1379), Expect = 3e-150, Method: Compositional matrix adjust.
Identities = 257/295 (88%), Positives = 274/295 (93%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI ++DTEV T FE D+AATQRY DS RFAGI RLYTARQVVEQRGTIP D+IVA
Sbjct 1 MAIIDSDTEVRT----SFEDDIAATQRYMDSPRFAGITRLYTARQVVEQRGTIPADYIVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AFY+RLRELFAA+KSITTFGPYSPGQAV+MKRMGIE IYLGGWATSAKGS+TEDP
Sbjct 57 REAAAAFYDRLRELFAAKKSITTFGPYSPGQAVAMKRMGIEGIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVP+DAAVLVRALLTADRNQ Y RL MSE QRA+TPAYD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPEDAAVLVRALLTADRNQQYQRLNMSEAQRASTPAYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNL+RRFVEVGV GYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLVRRFVEVGVAGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L++PSYK+CFLA++RRF
Sbjct 237 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLNIPSYKACFLALLRRF 291
>gi|15828074|ref|NP_302337.1| isocitrate lyase [Mycobacterium leprae TN]
gi|221230551|ref|YP_002503967.1| isocitrate lyase [Mycobacterium leprae Br4923]
gi|13093628|emb|CAC30940.1| isocitrate lyase [Mycobacterium leprae]
gi|219933658|emb|CAR72082.1| isocitrate lyase [Mycobacterium leprae Br4923]
Length=798
Score = 531 bits (1369), Expect = 5e-149, Method: Compositional matrix adjust.
Identities = 257/295 (88%), Positives = 272/295 (93%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI +T+TEVHT F Q+ VAATQ+YFD RFAGIIRLYTARQVVEQRGTIP D+ VA
Sbjct 37 MAIMDTNTEVHTLFTQE----VAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVA 92
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R+AA AFY RLRELFAA KS+TTFGPYSPGQAVS+KRMGIEAIYLGGWATSAKGS TEDP
Sbjct 93 RDAATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDP 152
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALL ADRNQ YLRL M+E+QRAATPAYD+RPFIIADA T
Sbjct 153 GPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRAATPAYDYRPFIIADADT 212
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGD HVRNLIRRFVE+GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 213 GHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 272
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYK+CFLA+VR F
Sbjct 273 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCF 327
>gi|13637587|sp|P46831.2|ACEA_MYCLE RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase;
Short=Isocitratase
Length=606
Score = 528 bits (1361), Expect = 4e-148, Method: Compositional matrix adjust.
Identities = 257/295 (88%), Positives = 272/295 (93%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI +T+TEVHT F Q+ VAATQ+YFD RFAGIIRLYTARQVVEQRGTIP D+ VA
Sbjct 1 MAIMDTNTEVHTLFTQE----VAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R+AA AFY RLRELFAA KS+TTFGPYSPGQAVS+KRMGIEAIYLGGWATSAKGS TEDP
Sbjct 57 RDAATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALL ADRNQ YLRL M+E+QRAATPAYD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRAATPAYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGD HVRNLIRRFVE+GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYK+CFLA+VR F
Sbjct 237 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCF 291
>gi|41407741|ref|NP_960577.1| isocitrate lyase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396094|gb|AAS03960.1| AceAb [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336457402|gb|EGO36411.1| isocitrate lyase [Mycobacterium avium subsp. paratuberculosis
S397]
Length=762
Score = 526 bits (1356), Expect = 2e-147, Method: Compositional matrix adjust.
Identities = 262/339 (78%), Positives = 288/339 (85%), Gaps = 12/339 (3%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI + +T+V F+ +VAATQRYFD RFA I RLYTARQV EQRGTI D+ VA
Sbjct 1 MAIIDKETQVRP----SFDDEVAATQRYFDDPRFARITRLYTARQVAEQRGTIRTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R+AA AFYERLRELFA +KSITTFGPYSPGQAV+MKRMGIE IYLGGWATSAKGS+TEDP
Sbjct 57 RDAAAAFYERLRELFAQKKSITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ YLRLQMSE+QRAAT YD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQQYLRLQMSEQQRAATKEYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIMRVPGIIVARTDAEAANL+DSRADERDQPFLLGAT LD+PSYK+CFLAMVRRF
Sbjct 237 DIMRVPGIIVARTDAEAANLLDSRADERDQPFLLGATNLDIPSYKACFLAMVRRFYELGV 296
Query 301 R--SSMVIFSM-----RLATASTRRPAV-GLSAKAFSAW 331
+ + +++++ ATA R + G+ + A +AW
Sbjct 297 KDLNGHLLYALPEAEYAEATAWLERQGIQGVISDAVNAW 335
>gi|559906|emb|CAA86357.1| isocitrate lyase [Mycobacterium leprae]
Length=606
Score = 526 bits (1354), Expect = 3e-147, Method: Compositional matrix adjust.
Identities = 256/295 (87%), Positives = 271/295 (92%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI +T+TEVHT F Q+ VAATQ+YFD RFAGIIRLYTARQVVEQRGTIP D+ VA
Sbjct 1 MAIMDTNTEVHTLFTQE----VAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R+AA AFY RLRELFAA KS+TTFGPYSPGQAVS+KRMGIEAIYLGGWATSAKGS TEDP
Sbjct 57 RDAATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALL ADRNQ YLRL M+E+Q AATPAYD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQLAATPAYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGD HVRNLIRRFVE+GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYK+CFLA+VR F
Sbjct 237 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCF 291
>gi|118464681|ref|YP_881969.1| isocitrate lyase [Mycobacterium avium 104]
gi|254775261|ref|ZP_05216777.1| isocitrate lyase [Mycobacterium avium subsp. avium ATCC 25291]
gi|118165968|gb|ABK66865.1| isocitrate lyase [Mycobacterium avium 104]
Length=762
Score = 526 bits (1354), Expect = 3e-147, Method: Compositional matrix adjust.
Identities = 254/295 (87%), Positives = 269/295 (92%), Gaps = 4/295 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI + +T+V F+ +VAATQRYFD RFA I RLYTARQV EQRGTI D+ VA
Sbjct 1 MAIIDKETQVRP----SFDDEVAATQRYFDDPRFARITRLYTARQVAEQRGTIRTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R+AA AFYERLRELFA +KSITTFGPYSPGQAV+MKRMGIE IYLGGWATSAKGS+TEDP
Sbjct 57 RDAAAAFYERLRELFAQKKSITTFGPYSPGQAVTMKRMGIEGIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ YLRLQMSE+QRAAT YD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQQYLRLQMSEQQRAATKEYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
DIMRVPGIIVARTDAEAANL+DSRADERDQPFLLGAT LD+PSYK+CFLAMVRRF
Sbjct 237 DIMRVPGIIVARTDAEAANLLDSRADERDQPFLLGATNLDIPSYKACFLAMVRRF 291
>gi|254821861|ref|ZP_05226862.1| isocitrate lyase [Mycobacterium intracellulare ATCC 13950]
Length=762
Score = 525 bits (1351), Expect = 7e-147, Method: Compositional matrix adjust.
Identities = 259/339 (77%), Positives = 285/339 (85%), Gaps = 12/339 (3%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI + DT+V F+ +VAATQ+YFD RF+ I RLYTARQV EQRGTIP D+ VA
Sbjct 1 MAIIDKDTQVRP----SFDDEVAATQQYFDDPRFSRITRLYTARQVAEQRGTIPTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R AA AFYERLRELFA +KSITTFGPYSPGQAV+MKRMGIE IYLGGWATSAKGS+TEDP
Sbjct 57 RNAAAAFYERLRELFAQKKSITTFGPYSPGQAVAMKRMGIEGIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ Y RLQMSE+QRAA P YD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQQYQRLQMSEKQRAAAPVYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIM+VPGIIVARTDAEAANL+DSRADERDQPFLLGAT L +PSYKSCFLA+VRRF
Sbjct 237 DIMKVPGIIVARTDAEAANLLDSRADERDQPFLLGATNLKIPSYKSCFLALVRRFYELGV 296
Query 301 R--SSMVIFSM-----RLATASTRRPAV-GLSAKAFSAW 331
+ + +++++ ATA R + GL + A +AW
Sbjct 297 KDLNGHLLYALPEGEYAEATAWLERQGIQGLVSDAVNAW 335
>gi|333990644|ref|YP_004523258.1| isocitrate lyase AceAb [Mycobacterium sp. JDM601]
gi|333486612|gb|AEF36004.1| isocitrate lyase AceAb [Mycobacterium sp. JDM601]
Length=765
Score = 519 bits (1337), Expect = 3e-145, Method: Compositional matrix adjust.
Identities = 247/297 (84%), Positives = 264/297 (89%), Gaps = 0/297 (0%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
M ET+ P ++D E DVAATQ YFDS RF GI RLY+ARQVVEQRGTIP D+IVA
Sbjct 1 MTTIETNAATSAPVQRDIEADVAATQHYFDSPRFEGITRLYSARQVVEQRGTIPSDYIVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AFY RLRELFAA+KSITTFGPYSPGQAV MKR+GIE IYLGGWATSAKGS TEDP
Sbjct 61 REAATAFYARLRELFAAKKSITTFGPYSPGQAVVMKRVGIEGIYLGGWATSAKGSITEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPD+AA LVRALLTADRNQHYLRLQM+E QRAATPA D+RPFIIADA T
Sbjct 121 GPDLASYPLSQVPDEAAGLVRALLTADRNQHYLRLQMTEEQRAATPAVDYRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVE GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEAGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN 297
D+M VPGIIVARTDAEAANL++SRADERDQPF+LG T L +PSYK+CFLAM R+F N
Sbjct 241 DLMGVPGIIVARTDAEAANLVESRADERDQPFILGTTNLKIPSYKACFLAMTRQFYN 297
>gi|342859571|ref|ZP_08716224.1| isocitrate lyase [Mycobacterium colombiense CECT 3035]
gi|342132703|gb|EGT85923.1| isocitrate lyase [Mycobacterium colombiense CECT 3035]
Length=762
Score = 519 bits (1336), Expect = 3e-145, Method: Compositional matrix adjust.
Identities = 257/339 (76%), Positives = 284/339 (84%), Gaps = 12/339 (3%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI + DT+V FE +VAATQ+YFD RF+ I RL+TARQV EQRGTIP D+ VA
Sbjct 1 MAIIDRDTQVRP----SFEDEVAATQQYFDDPRFSRITRLFTARQVAEQRGTIPTDYTVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
R AA AFYERLRELFA +KSITTFGPYSPGQAV+MKRMGIE IYLGGWATSAKGS+TEDP
Sbjct 57 RNAAAAFYERLRELFAEKKSITTFGPYSPGQAVAMKRMGIEGIYLGGWATSAKGSTTEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPDDAAVLVRALLTADRNQ Y RL MSE+QRA YD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPDDAAVLVRALLTADRNQQYQRLNMSEQQRATATEYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL
Sbjct 177 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWAS 300
DIM+VPGIIVARTDAEAANL+DSRADERDQPFLLGAT L++PSYKSCFLAMVRRF
Sbjct 237 DIMKVPGIIVARTDAEAANLLDSRADERDQPFLLGATNLNIPSYKSCFLAMVRRFYELGV 296
Query 301 R--SSMVIFSM-----RLATASTRRPAV-GLSAKAFSAW 331
+ + +++++ ATA R + G+ + A +AW
Sbjct 297 KELNGHLLYALPEGEYAEATAWLERQGIQGVISDAVNAW 335
>gi|120403959|ref|YP_953788.1| isocitrate lyase [Mycobacterium vanbaalenii PYR-1]
gi|119956777|gb|ABM13782.1| isocitrate lyase [Mycobacterium vanbaalenii PYR-1]
Length=766
Score = 509 bits (1311), Expect = 3e-142, Method: Compositional matrix adjust.
Identities = 262/364 (72%), Positives = 282/364 (78%), Gaps = 15/364 (4%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI E D + FE+DVA TQRYFDS RF GI RLYTARQV EQRGTIP D+ A
Sbjct 1 MAIIEADAFQPHATGEPFERDVAETQRYFDSPRFDGITRLYTARQVAEQRGTIPADYPTA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AFY LRELFA KSITTFGPYSPGQAV MKRMGIE +YLGGWATSAKGS +EDP
Sbjct 61 REAATAFYPHLRELFAKGKSITTFGPYSPGQAVVMKRMGIEGVYLGGWATSAKGSISEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVP++AA +VRALLTADRNQHYLRLQM QRAA P YD+RPFIIADA T
Sbjct 121 GPDLASYPLSQVPEEAASIVRALLTADRNQHYLRLQMDPEQRAAAPEYDYRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVE GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 181 GHGGDPHVRNLIRRFVEAGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF--TNW 298
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYKSCFLAMVRRF
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKSCFLAMVRRFYEKGM 300
Query 299 ASRSSMVIFSM---RLATAST---RRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFST 352
+ +++++ ATA+ R+ + L + SAW T SS AF
Sbjct 301 TELNGHLLYALPEGEYATATAWLDRQGVLNLIDETASAWQ-------AGTESSVDAAFDR 353
Query 353 RSSR 356
SR
Sbjct 354 VESR 357
>gi|145223847|ref|YP_001134525.1| isocitrate lyase [Mycobacterium gilvum PYR-GCK]
gi|145216333|gb|ABP45737.1| isocitrate lyase [Mycobacterium gilvum PYR-GCK]
Length=762
Score = 508 bits (1308), Expect = 6e-142, Method: Compositional matrix adjust.
Identities = 259/364 (72%), Positives = 286/364 (79%), Gaps = 19/364 (5%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI E D + TPFE +DV TQRYFDS RF GIIRLYTARQV EQRGTIP D+ VA
Sbjct 1 MAITEADLQSQTPFE----RDVVETQRYFDSPRFEGIIRLYTARQVAEQRGTIPADYPVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AF+ LRELF +SITTFGPYSPGQAV MKRMGIE IYLGGWATSAKGS +EDP
Sbjct 57 REAATAFFPHLRELFGQGRSITTFGPYSPGQAVVMKRMGIEGIYLGGWATSAKGSISEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVP++AA +VRALLTADRNQ YLRLQM+ Q+A TPAYD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPEEAAGIVRALLTADRNQQYLRLQMTPEQQATTPAYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVE GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 177 GHGGDPHVRNLIRRFVENGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWA- 299
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYKSC+LAM+RRF +
Sbjct 237 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKSCYLAMMRRFYDKGV 296
Query 300 -SRSSMVIFSM---RLATAST---RRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFST 352
+ +++++ ATA R+ + L + +AW T +S TAF
Sbjct 297 TELNGHLLYALPDGEYATAEAWLQRQGVLDLVDQTAAAWQDG-------TEASLDTAFDK 349
Query 353 RSSR 356
SR
Sbjct 350 VESR 353
>gi|315444176|ref|YP_004077055.1| isocitrate lyase [Mycobacterium sp. Spyr1]
gi|315262479|gb|ADT99220.1| isocitrate lyase [Mycobacterium sp. Spyr1]
Length=762
Score = 508 bits (1308), Expect = 6e-142, Method: Compositional matrix adjust.
Identities = 259/364 (72%), Positives = 286/364 (79%), Gaps = 19/364 (5%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MAI E D + TPFE +DV TQRYFDS RF GIIRLYTARQV EQRGTIP D+ VA
Sbjct 1 MAITEADLQSQTPFE----RDVVETQRYFDSPRFEGIIRLYTARQVAEQRGTIPADYPVA 56
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AF+ LRELF +SITTFGPYSPGQAV MKRMGIE IYLGGWATSAKGS +EDP
Sbjct 57 REAATAFFPHLRELFGQGRSITTFGPYSPGQAVVMKRMGIEGIYLGGWATSAKGSISEDP 116
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVP++AA +VRALLTADRNQ YLRLQM+ Q+A TPAYD+RPFIIADA T
Sbjct 117 GPDLASYPLSQVPEEAAGIVRALLTADRNQQYLRLQMTPEQQATTPAYDYRPFIIADADT 176
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVE GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 177 GHGGDPHVRNLIRRFVENGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 236
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWA- 299
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGAT L +PSYKSC+LAM+RRF +
Sbjct 237 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKSCYLAMMRRFYDKGV 296
Query 300 -SRSSMVIFSM---RLATAST---RRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFST 352
+ +++++ ATA R+ + L + +AW T +S TAF
Sbjct 297 TELNGHLLYALPDGEYATAEAWLQRQGVLDLVDQTAAAWQDG-------TEASLDTAFDK 349
Query 353 RSSR 356
SR
Sbjct 350 VESR 353
>gi|126432789|ref|YP_001068480.1| isocitrate lyase [Mycobacterium sp. JLS]
gi|126232589|gb|ABN95989.1| isocitrate lyase [Mycobacterium sp. JLS]
Length=765
Score = 501 bits (1290), Expect = 7e-140, Method: Compositional matrix adjust.
Identities = 243/281 (87%), Positives = 254/281 (91%), Gaps = 1/281 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F+++VA TQRY DS RF GI RLYTARQVVEQRGTIPVDH VAREAA AFY RLRELF+
Sbjct 13 FDQEVAETQRYLDSPRFEGITRLYTARQVVEQRGTIPVDHTVAREAATAFYPRLRELFSQ 72
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
KSITTFGPYSPGQAV+MKR GIE IYLGGWATSAKGS+ EDPGPDLASYPLSQVPD+AA
Sbjct 73 GKSITTFGPYSPGQAVTMKRAGIEGIYLGGWATSAKGSTDEDPGPDLASYPLSQVPDEAA 132
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPA-YDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
LVRALLTADRNQHYLRL+MSE QRAA P DFRPFIIADA TGHGGDPHVRNLIRRFV
Sbjct 133 GLVRALLTADRNQHYLRLRMSEEQRAAAPPPVDFRPFIIADADTGHGGDPHVRNLIRRFV 192
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
E GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQLDIM VPGIIVARTDAE
Sbjct 193 EAGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQLDIMGVPGIIVARTDAE 252
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN 297
AANLIDSRADERDQPFLLGAT L +PSYKSCFLAM+R F +
Sbjct 253 AANLIDSRADERDQPFLLGATNLSIPSYKSCFLAMMRSFHD 293
>gi|108797167|ref|YP_637364.1| isocitrate lyase [Mycobacterium sp. MCS]
gi|119866252|ref|YP_936204.1| isocitrate lyase [Mycobacterium sp. KMS]
gi|108767586|gb|ABG06308.1| isocitrate lyase [Mycobacterium sp. MCS]
gi|119692341|gb|ABL89414.1| isocitrate lyase [Mycobacterium sp. KMS]
Length=765
Score = 501 bits (1290), Expect = 8e-140, Method: Compositional matrix adjust.
Identities = 243/281 (87%), Positives = 254/281 (91%), Gaps = 1/281 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F+++VA TQRY DS RF GI RLYTARQVVEQRGTIPVDH VAREAA AFY RLRELF+
Sbjct 13 FDQEVAETQRYLDSPRFEGITRLYTARQVVEQRGTIPVDHTVAREAATAFYPRLRELFSQ 72
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
KSITTFGPYSPGQAV+MKR GIE IYLGGWATSAKGS+ EDPGPDLASYPLSQVPD+AA
Sbjct 73 GKSITTFGPYSPGQAVTMKRAGIEGIYLGGWATSAKGSTDEDPGPDLASYPLSQVPDEAA 132
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPA-YDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
LVRALLTADRNQHYLRL+MSE QRAA P DFRPFIIADA TGHGGDPHVRNLIRRFV
Sbjct 133 GLVRALLTADRNQHYLRLRMSEEQRAAAPPPVDFRPFIIADADTGHGGDPHVRNLIRRFV 192
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
E GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQLDIM VPGIIVARTDAE
Sbjct 193 EAGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQLDIMGVPGIIVARTDAE 252
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN 297
AANLIDSRADERDQPFLLGAT L +PSYKSCFLAM+R F +
Sbjct 253 AANLIDSRADERDQPFLLGATNLSIPSYKSCFLAMMRSFHD 293
>gi|118471001|ref|YP_888007.1| isocitrate lyase [Mycobacterium smegmatis str. MC2 155]
gi|118172288|gb|ABK73184.1| isocitrate lyase [Mycobacterium smegmatis str. MC2 155]
Length=769
Score = 500 bits (1288), Expect = 1e-139, Method: Compositional matrix adjust.
Identities = 242/297 (82%), Positives = 257/297 (87%), Gaps = 0/297 (0%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
MA E + + +DF+ +VAATQ YFDS RF GI RLY+ARQVVEQRGTI DH VA
Sbjct 1 MATIEANAHNLSSSAKDFDSEVAATQAYFDSPRFEGITRLYSARQVVEQRGTIATDHTVA 60
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
REAA AF+ LRELFA +KSITTFGPYSPGQAV MKRMGI IYLGGWATSAKGS +EDP
Sbjct 61 REAAEAFHPYLRELFAQKKSITTFGPYSPGQAVVMKRMGIGGIYLGGWATSAKGSISEDP 120
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLASYPLSQVPD+AA LVRALLTADRNQHYLRLQM+ QR A P D+RPFIIADA T
Sbjct 121 GPDLASYPLSQVPDEAAGLVRALLTADRNQHYLRLQMTPEQREAQPPVDYRPFIIADADT 180
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGGDPHVRNLIRRFVE GVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLN ARFQL
Sbjct 181 GHGGDPHVRNLIRRFVESGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNTARFQL 240
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN 297
DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLG T L +PSYKSCFLAM+RRF +
Sbjct 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGVTNLKIPSYKSCFLAMMRRFYD 297
>gi|197122060|ref|YP_002134011.1| isocitrate lyase [Anaeromyxobacter sp. K]
gi|196171909|gb|ACG72882.1| isocitrate lyase [Anaeromyxobacter sp. K]
Length=748
Score = 449 bits (1156), Expect = 2e-124, Method: Compositional matrix adjust.
Identities = 214/279 (77%), Positives = 247/279 (89%), Gaps = 0/279 (0%)
Query 17 DFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFA 76
DFE++VAA +R+F+S RFAGI R++TAR+VVEQRGTI D+ VAREAA AF+ RLRELF
Sbjct 2 DFEQEVAALRRWFESPRFAGIRRIHTAREVVEQRGTIRQDYPVAREAAEAFHARLRELFQ 61
Query 77 ARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
R+ ITTFGPYSPGQAV+MKRMGIEAIYLGGWATSAKGS EDPGPDLASYPLSQVPD+A
Sbjct 62 QRRCITTFGPYSPGQAVAMKRMGIEAIYLGGWATSAKGSVQEDPGPDLASYPLSQVPDEA 121
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
A +VRALLTADRNQH+ R +M+E QR ATPA DFRPFIIADA TGHGGD VRNL+RRFV
Sbjct 122 APIVRALLTADRNQHHARSRMTEEQRRATPAVDFRPFIIADADTGHGGDAQVRNLVRRFV 181
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
EVGVPGYHIEDQ+PG KKCGHQGGKVLV DEQ+KRL+AARFQLD+M VPGI+VARTDAE
Sbjct 182 EVGVPGYHIEDQKPGVKKCGHQGGKVLVAEDEQLKRLSAARFQLDLMGVPGIVVARTDAE 241
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
+A L+D R DERDQPF+LGA+ L VP++++ FLA++RRF
Sbjct 242 SATLLDGRGDERDQPFILGASNLAVPAFRAAFLAILRRF 280
>gi|220916830|ref|YP_002492134.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-1]
gi|219954684|gb|ACL65068.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-1]
Length=748
Score = 447 bits (1151), Expect = 1e-123, Method: Compositional matrix adjust.
Identities = 212/279 (76%), Positives = 247/279 (89%), Gaps = 0/279 (0%)
Query 17 DFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFA 76
DFE++VAA +R+F+S RFAGI R++TAR+V+EQRGTI D+ VAREAA AF+ RLRELF
Sbjct 2 DFEQEVAALRRWFESPRFAGIRRIHTAREVMEQRGTIRQDYPVAREAAEAFHARLRELFQ 61
Query 77 ARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
R+ ITTFGPYSPGQAV+MK+MGIEAIYLGGWATSAKGS EDPGPDLASYPLSQVPD+A
Sbjct 62 QRRCITTFGPYSPGQAVAMKKMGIEAIYLGGWATSAKGSVQEDPGPDLASYPLSQVPDEA 121
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
A +VRALLTADRNQH+ R +M+E QR ATPA DFRPFIIADA TGHGGD VRNL+RRFV
Sbjct 122 APIVRALLTADRNQHHARSRMTEEQRRATPAVDFRPFIIADADTGHGGDAQVRNLVRRFV 181
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
EVGVPGYHIEDQ+PG KKCGHQGGKVLV DEQ+KRL+AARFQLD+M VPGI+VARTDAE
Sbjct 182 EVGVPGYHIEDQKPGVKKCGHQGGKVLVAEDEQLKRLSAARFQLDLMGVPGIVVARTDAE 241
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
+A L+D R DERDQPF+LGA+ L VP++++ FLA++RRF
Sbjct 242 SATLLDGRGDERDQPFILGASNLAVPAFRAAFLAILRRF 280
>gi|86158643|ref|YP_465428.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-C]
gi|85775154|gb|ABC81991.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-C]
Length=749
Score = 446 bits (1147), Expect = 3e-123, Method: Compositional matrix adjust.
Identities = 212/279 (76%), Positives = 247/279 (89%), Gaps = 0/279 (0%)
Query 17 DFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFA 76
DFE++VAA +R+F+S RFAGI R++TAR+V+EQRGTI D+ VAREAA AF+ RLRELF
Sbjct 2 DFEQEVAALRRWFESPRFAGIRRIHTAREVMEQRGTIRQDYPVAREAAEAFHARLRELFQ 61
Query 77 ARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
R+ ITTFGPYSPGQAV+MK+MGIEAIYLGGWATSAKGS EDPGPDLASYPLSQVPD+A
Sbjct 62 QRRCITTFGPYSPGQAVAMKKMGIEAIYLGGWATSAKGSVQEDPGPDLASYPLSQVPDEA 121
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
A +VRALLTADRNQH+ R +M+E QR ATPA DFRPFIIADA TGHGGD VRNL+RRFV
Sbjct 122 APIVRALLTADRNQHHARSRMTEEQRRATPAVDFRPFIIADADTGHGGDAQVRNLVRRFV 181
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
EVGVPGYHIEDQ+PG KKCGHQGGKVLV DEQ+KRL+AARFQLD+M VPGI+VARTDAE
Sbjct 182 EVGVPGYHIEDQKPGVKKCGHQGGKVLVAEDEQLKRLSAARFQLDLMGVPGIVVARTDAE 241
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
+A L+D R DERDQPF+LGA+ L VP++++ FLA++RRF
Sbjct 242 SATLLDGRGDERDQPFILGASNLAVPAFRAAFLAILRRF 280
>gi|153004450|ref|YP_001378775.1| isocitrate lyase [Anaeromyxobacter sp. Fw109-5]
gi|152028023|gb|ABS25791.1| isocitrate lyase [Anaeromyxobacter sp. Fw109-5]
Length=750
Score = 437 bits (1123), Expect = 2e-120, Method: Compositional matrix adjust.
Identities = 207/279 (75%), Positives = 242/279 (87%), Gaps = 0/279 (0%)
Query 17 DFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFA 76
DFEK+V +R+F S RFAGI R+++AR+VVEQRGTI D+ VAR AA AFY+RLR+LF
Sbjct 2 DFEKEVEEVRRWFASPRFAGIRRVHSAREVVEQRGTIRPDYAVARGAAEAFYDRLRQLFE 61
Query 77 ARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
++ +TTFGPYSPGQAV++K+MGIEAIYLGGWATSAKGSS EDPGPDLASYPLSQVP++A
Sbjct 62 QQRCVTTFGPYSPGQAVAIKKMGIEAIYLGGWATSAKGSSHEDPGPDLASYPLSQVPEEA 121
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
A LVRALLTAD+NQ + R +M+E QR ATP DFRPFIIADA TGHGGD HVRNLIRRFV
Sbjct 122 ATLVRALLTADKNQLHTRARMTEEQRRATPEVDFRPFIIADADTGHGGDAHVRNLIRRFV 181
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
EVGVPGYHIEDQ+PG KKCGHQGGKVLV DEQ+KRL+AARFQLDIM VPGIIVARTDAE
Sbjct 182 EVGVPGYHIEDQKPGVKKCGHQGGKVLVSEDEQLKRLSAARFQLDIMGVPGIIVARTDAE 241
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRF 295
+A L+D R D+RDQPF+LG L +P++K+ FLAM+R+F
Sbjct 242 SATLLDGRGDDRDQPFILGVRNLSLPTFKAAFLAMLRQF 280
>gi|328856720|gb|EGG05840.1| hypothetical protein MELLADRAFT_48703 [Melampsora larici-populina
98AG31]
Length=537
Score = 239 bits (610), Expect = 5e-61, Method: Compositional matrix adjust.
Identities = 128/314 (41%), Positives = 178/314 (57%), Gaps = 12/314 (3%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
+Q FE +VAA ++ + S R+ G++R YTA QVV +RGT+P+++ + + + L
Sbjct 7 QQIFEAEVAALKQVWQSPRYKGLVRPYTAEQVVSKRGTLPMNY-TSNQIGKKLWNILSNH 65
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
F T+G P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP+
Sbjct 66 FKNGTPSHTYGALDPVQVTQMAKY-LETVYVSGWQSSSTASSTNEPGPDLADYPSNTVPN 124
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L A L DR Q RL+M+ QR TP D+ IIADA TGHGG V L +
Sbjct 125 KVEHLFMAQLFHDRRQREARLRMTPEQRNKTPPTDYLRPIIADADTGHGGLTAVMKLAKM 184
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
FVE G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V I+V RTD
Sbjct 185 FVEKGASGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRLQFDIMGVENIVVCRTD 244
Query 255 AEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFT----------NWASRSSM 304
AEAA L+ + DERD ++LG T ++ R+ +W ++++
Sbjct 245 AEAATLLSTNVDERDHAYILGTTNPNIGHLVDIMNTAQRQGKSGDALQNIEDDWTLKANL 304
Query 305 VIFSMRLATASTRR 318
V++S +++A ++
Sbjct 305 VLYSDAISSAMKKK 318
>gi|301111828|ref|XP_002904993.1| isocitrate lyase [Phytophthora infestans T30-4]
gi|262095323|gb|EEY53375.1| isocitrate lyase [Phytophthora infestans T30-4]
Length=537
Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 127/270 (48%), Positives = 168/270 (63%), Gaps = 2/270 (0%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
E D+ + V T+ + RF + R Y A VV+ +GTIP + A + Y+ LREL
Sbjct 24 ESDYAQRVKQTEAFIRDERFQYVKRPYGAEDVVKLQGTIPAANAGA-AMSRKLYKMLREL 82
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
AA+K+ TFG Q M + + +IY+ GW +S+ S++ +PGPD+A YP+ VP+
Sbjct 83 QAAQKTSHTFGALDTIQVTQMAKH-LSSIYVSGWQSSSTASTSNEPGPDVADYPMDTVPN 141
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L RA L DR Q+ R +M+ +RA TP DF I+ADA TGHGG V L +
Sbjct 142 KVDQLFRAQLFHDRKQYEARRRMTAEERARTPPTDFLRPIVADADTGHGGLTAVMKLTKM 201
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
FVE G G H+EDQ+PGTKKCGH GGKVLV E I+RL AAR Q DI+ P +IVARTD
Sbjct 202 FVERGAAGIHLEDQKPGTKKCGHMGGKVLVSVQEHIQRLIAARLQADILGSPLVIVARTD 261
Query 255 AEAANLIDSRADERDQPFLLGATKLDVPSY 284
AEAA L+D+ D RD PF++GAT L+V +Y
Sbjct 262 AEAATLLDNNIDPRDHPFIIGATNLNVETY 291
>gi|164656513|ref|XP_001729384.1| hypothetical protein MGL_3419 [Malassezia globosa CBS 7966]
gi|159103275|gb|EDP42170.1| hypothetical protein MGL_3419 [Malassezia globosa CBS 7966]
Length=298
Score = 235 bits (600), Expect = 7e-60, Method: Compositional matrix adjust.
Identities = 124/264 (47%), Positives = 157/264 (60%), Gaps = 2/264 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F+K+V ++++ S RF G+ R YTA VV +RGT+ H ++ E A + L
Sbjct 12 FQKEVEDVKQWWKSPRFVGVTRPYTAEAVVSKRGTMR-QHYLSNEQAKKMWGLLEHHAKN 70
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
+ + TFG P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP+
Sbjct 71 KTTSHTFGALDPVQVSQMAKY-LETVYVSGWQSSSTASSTNEPGPDLADYPSNTVPNKVE 129
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L A L DR Q R M+ QRA TP D+ I+ADA TGHGG V L + FVE
Sbjct 130 HLFMAQLFHDRKQQDARRSMTAEQRAKTPYVDYMRPIVADADTGHGGLTAVMKLAKMFVE 189
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V ++VARTD+EA
Sbjct 190 KGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLIAIRLQYDIMGVENLVVARTDSEA 249
Query 258 ANLIDSRADERDQPFLLGATKLDV 281
A LI + DERD PF+LG T D+
Sbjct 250 ATLITTNVDERDHPFILGTTNRDL 273
>gi|331218780|ref|XP_003322067.1| isocitrate lyase [Puccinia graminis f. sp. tritici CRL 75-36-700-3]
gi|309301057|gb|EFP77648.1| isocitrate lyase [Puccinia graminis f. sp. tritici CRL 75-36-700-3]
Length=536
Score = 231 bits (589), Expect = 1e-58, Method: Compositional matrix adjust.
Identities = 123/268 (46%), Positives = 160/268 (60%), Gaps = 4/268 (1%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGA-FYERLRE 73
+Q FE++V + + + S R+ G++R YTA QVV +RGT+P+ + E G + L +
Sbjct 6 QQIFEQEVNSLKAKWASPRYKGLVRPYTAEQVVGKRGTLPISY--PSEVVGKKLWNLLNQ 63
Query 74 LFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVP 133
+ T+G P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP
Sbjct 64 HYKNGTPSHTYGALDPIQVTQMAKY-LETVYVSGWQSSSTASSTNEPGPDLADYPSNTVP 122
Query 134 DDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIR 193
+ L A L DR Q RL+M+ +R TP D+ IIADA TGHGG V L +
Sbjct 123 NKVEHLFMAQLFHDRRQREARLRMTPEERKKTPPVDYIRPIIADADTGHGGLTAVMKLAK 182
Query 194 RFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVART 253
FVE G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V I+VART
Sbjct 183 MFVEKGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRLQFDIMGVENIVVART 242
Query 254 DAEAANLIDSRADERDQPFLLGATKLDV 281
DAEAA L+ + DERD ++LG T +V
Sbjct 243 DAEAATLLSTNVDERDHGYILGTTNPNV 270
>gi|336370073|gb|EGN98414.1| hypothetical protein SERLA73DRAFT_55765 [Serpula lacrymans var.
lacrymans S7.3]
gi|336382817|gb|EGO23967.1| hypothetical protein SERLADRAFT_370809 [Serpula lacrymans var.
lacrymans S7.9]
Length=539
Score = 228 bits (581), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 130/323 (41%), Positives = 177/323 (55%), Gaps = 12/323 (3%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F+ +VA +++F S RFA + R YTA QVV +RGTIP+ + + F L E
Sbjct 9 FQAEVAEVEQWFKSPRFARVKRPYTAAQVVSKRGTIPIKYPSGLQGKKLF-ALLAEHAKN 67
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
T+G P Q M + +E +Y+ GW +S+ +ST +PGPDLA YP + VP+
Sbjct 68 GTPSHTYGALDPVQITQMAKY-LETVYVSGWQSSSTAASTNEPGPDLADYPSNTVPNKVE 126
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L A L DR Q R MSE + AATP D+ ++ADA TGHGG + L + FVE
Sbjct 127 HLFMAQLFHDRKQREARSNMSEAELAATPYIDYLRPLVADADTGHGGLTAIMKLAKMFVE 186
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V +++ARTD+EA
Sbjct 187 KGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRLQFDIMGVENLVIARTDSEA 246
Query 258 ANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN----------WASRSSMVIF 307
A LI + D+RD F+LG+T +P + + + W +++ +F
Sbjct 247 ATLITTNIDDRDHAFILGSTNPSLPPLVNVMGDAEKAGKSGDDLQAIEDAWTVSANLQLF 306
Query 308 SMRLATASTRRPAVGLSAKAFSA 330
S LA A ++ A + +F A
Sbjct 307 SETLANAIAKQGASKATVDSFIA 329
>gi|302689573|ref|XP_003034466.1| isocitrate lyase [Schizophyllum commune H4-8]
gi|300108161|gb|EFI99563.1| isocitrate lyase [Schizophyllum commune H4-8]
Length=538
Score = 226 bits (577), Expect = 4e-57, Method: Compositional matrix adjust.
Identities = 129/323 (40%), Positives = 175/323 (55%), Gaps = 12/323 (3%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F K+VA ++++ S RF + R YTA VV +RGT+P+ + + + L E
Sbjct 8 FAKEVAEVEQWWKSPRFERVKRPYTAADVVSKRGTLPIQY-PSNVQGKKLWSILGEHAKR 66
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
T+G P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP+
Sbjct 67 GTPSHTYGALDPVQVTQMAKY-LETVYVSGWQSSSTASSTNEPGPDLADYPYNTVPNKVE 125
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L +A L DR Q R +S+ + +TP+ D+ I+ADA TGHGG V L + FVE
Sbjct 126 HLFQAQLFHDRKQREARSHLSDSELTSTPSIDYLRPIVADADTGHGGLTAVMKLTKLFVE 185
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DI+ V + +ARTD+EA
Sbjct 186 KGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRLQYDILGVENLAIARTDSEA 245
Query 258 ANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFT----------NWASRSSMVIF 307
A LI S D RD F+LG+T + + LA R NW +++++ +F
Sbjct 246 ATLITSNIDARDHAFILGSTNPSIGALNDVMLAAEREGKNGEELQATEDNWLAQANLQLF 305
Query 308 SMRLATASTRRPAVGLSAKAFSA 330
S LA A T A + F A
Sbjct 306 SKTLADALTAEGASAANVDKFLA 328
>gi|71020403|ref|XP_760432.1| hypothetical protein UM04285.1 [Ustilago maydis 521]
gi|46100101|gb|EAK85334.1| hypothetical protein UM04285.1 [Ustilago maydis 521]
Length=531
Score = 224 bits (570), Expect = 3e-56, Method: Compositional matrix adjust.
Identities = 122/267 (46%), Positives = 159/267 (60%), Gaps = 4/267 (1%)
Query 16 QDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELF 75
+ F ++V A ++++ S RFA R YTA QVV +RGT+ + +A + +L E
Sbjct 7 KQFAEEVEAVKQWWKSPRFAHTTRPYTAEQVVSKRGTLKQTYPSDVQAKKLW--KLLEDH 64
Query 76 AARKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
A++ + + T+G P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP
Sbjct 65 ASKGTTSHTYGALDPVQVTQMAKH-LETVYVSGWQSSSTASSTNEPGPDLADYPYNTVPL 123
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L A L DR Q R +S QRA TP D+ I+ADA TGHGG V L +
Sbjct 124 KVEHLFMAQLFHDRKQREERTNLSPEQRAKTPVIDYLRPIVADADTGHGGLTAVMKLTKL 183
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
FVE G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V ++VARTD
Sbjct 184 FVEKGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLIAIRLQYDIMGVENLVVARTD 243
Query 255 AEAANLIDSRADERDQPFLLGATKLDV 281
+EAA LI + DERD F+LG T ++
Sbjct 244 SEAATLITTNVDERDHSFILGTTHTEL 270
>gi|325188195|emb|CCA22736.1| isocitrate lyase putative [Albugo laibachii Nc14]
Length=545
Score = 223 bits (568), Expect = 4e-56, Method: Compositional matrix adjust.
Identities = 126/319 (40%), Positives = 180/319 (57%), Gaps = 19/319 (5%)
Query 20 KDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPV---DHIVAREAAGAFYERLRELFA 76
K + Q + SRF I R Y A VV+ +G + V +++R+ Y LR+L
Sbjct 34 KRLQEMQAFLSDSRFRYISRPYKAEDVVKLQGNLDVTFASSVLSRK----LYNMLRDLHD 89
Query 77 ARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
+ TFG Q + M + + +Y+ GW +S+ S++ +PGPD+A YP+ VP+
Sbjct 90 RGQVSHTFGALDTIQVIQMAKY-MSTVYVSGWQSSSTASTSNEPGPDVADYPMDTVPNKV 148
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
L RA DR Q+ +R +++E++R P D+ IIADA TGHGG V L + F+
Sbjct 149 DQLFRAQQFHDRKQYEMRRRLTEKERTENPPVDYLRPIIADADTGHGGLTAVMKLTKMFI 208
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
E G G HIEDQ+PGTKKCGH GGKVLV + E I+RL AAR D M+ P +I+ARTDAE
Sbjct 209 ERGAAGIHIEDQKPGTKKCGHMGGKVLVSTQEHIQRLVAARLLADTMKSPLVIIARTDAE 268
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTN--WASRSSMVIF--SMRLA 312
A+ L+D+ D RD PF++GAT LD S FL +R + W + + + + ++RLA
Sbjct 269 ASTLLDNNIDGRDHPFIIGATNLDTES----FLEASKRDSTGGWDTCAQAMTYPEAVRLA 324
Query 313 TASTRRPAVGLSAKAFSAW 331
+ P K SAW
Sbjct 325 IEKSNHPD---KTKQLSAW 340
>gi|343425324|emb|CBQ68860.1| probable isocitrate lyase [Sporisorium reilianum SRZ2]
Length=531
Score = 221 bits (563), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 121/262 (47%), Positives = 150/262 (58%), Gaps = 4/262 (1%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F+++V A ++++ RFA R YTA QVV +RGT+ G + E AA
Sbjct 9 FQEEVEAVKQWWKIPRFANTTRPYTAEQVVSKRGTL--KQTYPSNIQGKKLWKTLEAHAA 66
Query 78 RKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
+ + T+G P Q M + +E +Y+ GW S+ SST +PGPDLA YP + VP
Sbjct 67 NGTTSHTYGALDPVQVTQMAKH-LETVYVSGWQCSSTASSTNEPGPDLADYPYNTVPLKV 125
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
L A L DR Q R +S QRA TP D+ I+ADA TGHGG V L + FV
Sbjct 126 EHLFMAQLFHDRKQREERTNLSPEQRAKTPVVDYLRPIVADADTGHGGLTAVMKLTKLFV 185
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
E G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V ++VARTD+E
Sbjct 186 EKGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQYDIMGVENLVVARTDSE 245
Query 257 AANLIDSRADERDQPFLLGATK 278
AA LI + DERD F+LG T
Sbjct 246 AATLITTNVDERDHAFILGTTN 267
>gi|298706764|emb|CBJ29687.1| Isocitrate lyase (Isocitrase) (Isocitratase) (ICL) [Ectocarpus
siliculosus]
Length=589
Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 120/263 (46%), Positives = 154/263 (59%), Gaps = 8/263 (3%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDH---IVAREAAGAFYERLREL 74
F DV AT+R++ S RF R ++A +VV RGT+P + I AR+ +E L +
Sbjct 28 FNHDVEATKRWWGSPRFRYTKRPFSAEEVVSLRGTLPETYPSDIQARK----LWELLEKK 83
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
A TFG P Q + M +E +Y+ GW S+ S++ +PGPD A YP VP+
Sbjct 84 HALGDFSHTFGALDPVQVIEMAPH-LETVYVSGWQCSSTASTSNEPGPDFADYPYDTVPN 142
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L RA DR Q+ R MSE ++ + PA D+ IIAD TGHGG V L +
Sbjct 143 KVDQLFRAQRHHDRRQNDERCSMSEGEQLSAPAVDYLRPIIADGDTGHGGLTAVMKLTKM 202
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
F+E G G H EDQ+PGTKKCGH GGKVLV E RL AAR Q DIM +IVARTD
Sbjct 203 FIEKGAAGIHFEDQKPGTKKCGHMGGKVLVSMQEHCDRLVAARLQADIMGTETVIVARTD 262
Query 255 AEAANLIDSRADERDQPFLLGAT 277
AEAA+L+D+ D RD PF++GAT
Sbjct 263 AEAASLLDNNVDPRDHPFIVGAT 285
>gi|170089369|ref|XP_001875907.1| isocitrate lyase icl [Laccaria bicolor S238N-H82]
gi|164649167|gb|EDR13409.1| isocitrate lyase icl [Laccaria bicolor S238N-H82]
Length=538
Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 127/314 (41%), Positives = 169/314 (54%), Gaps = 14/314 (4%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F +VA ++++ + RFA + R YTA VV +RGT+ + + G +L A
Sbjct 8 FAHEVAQVEQWWKNPRFARVKRPYTAADVVAKRGTLAIQY--PSNVQGKKLWKLLSEHAK 65
Query 78 RKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDA 136
R + + T+G P Q M + +E +Y+ GW +S+ SST +PGPDLA YP + VP+
Sbjct 66 RGTPSHTYGALDPVQVTQMAKY-LETVYVSGWQSSSTASSTNEPGPDLADYPSNTVPNKV 124
Query 137 AVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFV 196
L A L DR Q R +SE + A TP D+ I+ADA TGHGG V L + FV
Sbjct 125 EHLFMAQLFHDRKQREARSSLSEAELAKTPVVDYLRPIVADADTGHGGLTAVMKLTKMFV 184
Query 197 EVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAE 256
E G G H+EDQ PGTKKCGH GKVLVP E I RL A R Q DIM V + +ARTD+E
Sbjct 185 EKGAAGIHVEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQYDIMGVENLAIARTDSE 244
Query 257 AANLIDSRADERDQPFLLGATKLDVPSYKSCFLA----------MVRRFTNWASRSSMVI 306
AA LI S D RD F+LGAT P + + W S +++ +
Sbjct 245 AATLITSNIDGRDHAFILGATNPSQPPLNDVMVEAELAGKSGDQLQAIEDQWISSANLEL 304
Query 307 FSMRLATASTRRPA 320
FS LA A ++ A
Sbjct 305 FSTTLAKALGKQGA 318
>gi|340914878|gb|EGS18219.1| isocitrate lyase-like protein [Chaetomium thermophilum var. thermophilum
DSM 1495]
Length=548
Score = 216 bits (549), Expect = 6e-54, Method: Compositional matrix adjust.
Identities = 115/276 (42%), Positives = 159/276 (58%), Gaps = 2/276 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F K+V ++++ R+ R +TA Q+V +RG + +++ + + A ++ L + FA
Sbjct 20 FAKEVEEVKKWWSDPRWRYTKRPFTAEQIVNKRGNLKIEY-ASNQQAKKLWKILEKRFAE 78
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
R + T+G P M + ++ +Y+ GW +S+ SST++PGPDLA YP + VP+
Sbjct 79 RDASYTYGCLEPTAVTQMAKY-LDTVYVSGWQSSSTASSTDEPGPDLADYPYTTVPNKVG 137
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L A L DR Q R+ + + QRA P D+ IIADA TGHGG V L + F+E
Sbjct 138 HLFMAQLFHDRKQRQERMSVPKEQRAKLPNVDYLRPIIADADTGHGGLTAVMKLTKLFIE 197
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM +++ARTDAEA
Sbjct 198 KGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRAQADIMGHDLVVIARTDAEA 257
Query 258 ANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVR 293
A LI S D RD F+LG+T ++ LA R
Sbjct 258 ATLITSTIDPRDHAFILGSTNPNLQPLNDLMLAAER 293
>gi|8134297|sp|O13439.1|ACEA_COPCI RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase;
Short=Isocitratase
gi|2569955|emb|CAA67367.1| isocitrate lyase [Coprinopsis cinerea]
Length=537
Score = 216 bits (549), Expect = 7e-54, Method: Compositional matrix adjust.
Identities = 120/272 (45%), Positives = 158/272 (59%), Gaps = 2/272 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F +VA +R++ S RFA + R YTA VV +RGTI +++ + ++ L E
Sbjct 8 FASEVAEVERWWKSPRFARVNRPYTAADVVSKRGTIKINYPSDVQGK-KLWKLLSEHAKN 66
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
T+G P Q M + +E +Y+ GW +S+ SS+ +PGPDLA YP + VP+
Sbjct 67 GTPSHTYGALDPVQVTKMAKY-LETVYVSGWQSSSTASSSNEPGPDLADYPSNTVPNKVE 125
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L A L DR Q R +MS+ + A TP D+ I+ADA TGHGG V L + FVE
Sbjct 126 HLFMAQLFHDRKQREARSRMSDAELANTPVIDYLRPIVADADTGHGGLTAVMKLTKMFVE 185
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V ++VARTD+EA
Sbjct 186 KGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQYDIMGVENLVVARTDSEA 245
Query 258 ANLIDSRADERDQPFLLGATKLDVPSYKSCFL 289
A LI S D+RD PF+ G+T +P + +
Sbjct 246 ATLITSNIDDRDHPFIQGSTNPSLPPLNNVMV 277
>gi|169858104|ref|XP_001835698.1| isocitrate lyase [Coprinopsis cinerea okayama7#130]
gi|189027294|sp|A8NR45.1|ACEA_COPC7 RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase;
Short=Isocitratase
gi|116503148|gb|EAU86043.1| isocitrate lyase [Coprinopsis cinerea okayama7#130]
Length=538
Score = 215 bits (548), Expect = 8e-54, Method: Compositional matrix adjust.
Identities = 120/272 (45%), Positives = 158/272 (59%), Gaps = 2/272 (0%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAA 77
F +VA +R++ S RFA + R YTA VV +RGTI +++ + ++ L E
Sbjct 8 FAAEVAEVERWWKSPRFARVNRPYTAADVVSKRGTIKINYPSDVQGK-KLWKLLSEHAKN 66
Query 78 RKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAA 137
T+G P Q M + +E +Y+ GW +S+ SS+ +PGPDLA YP + VP+
Sbjct 67 GTPSHTYGALDPVQVTQMAKY-LETVYVSGWQSSSTASSSNEPGPDLADYPSNTVPNKVE 125
Query 138 VLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVE 197
L A L DR Q R +MS+ + A TP D+ I+ADA TGHGG V L + FVE
Sbjct 126 HLFMAQLFHDRKQREARSRMSDAELANTPVIDYLRPIVADADTGHGGLTAVMKLTKMFVE 185
Query 198 VGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEA 257
G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V ++VARTD+EA
Sbjct 186 KGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQYDIMGVENLVVARTDSEA 245
Query 258 ANLIDSRADERDQPFLLGATKLDVPSYKSCFL 289
A LI S D+RD PF+ G+T +P + +
Sbjct 246 ATLITSNIDDRDHPFIQGSTNPSLPPLNNVMV 277
>gi|145843726|gb|ABP96877.1| isocitrate lyase [Tuber borchii]
Length=545
Score = 215 bits (547), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 115/264 (44%), Positives = 155/264 (59%), Gaps = 2/264 (0%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
++ FE +V A ++++ S R+ R +TA Q+V +RG +P+ + + + + + L +
Sbjct 11 QKAFEAEVEAVKQWWSSPRWHYTKRPFTAEQIVSKRGNLPIFY-PSNDQSKKLWGILEKK 69
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
F +++ T+G P M + +E +Y+ GW S+ SST +P PDLA YP+ VP+
Sbjct 70 FDSKEPSYTYGCLDPVMVTQMAKY-LETVYVSGWQCSSTASSTHEPSPDLADYPMDTVPN 128
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L +A L DR Q RL + +RA P+ D+ IIADA TGHGG V L R
Sbjct 129 KVDHLFKAQLFHDRKQREARLSVPVSERANQPSVDYLRPIIADADTGHGGLTAVMKLTRL 188
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
F+E G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V + VARTD
Sbjct 189 FIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVGEHINRLVAIRAQADIMGVDLLSVARTD 248
Query 255 AEAANLIDSRADERDQPFLLGATK 278
+EAA LI S D RD PF+LG T
Sbjct 249 SEAATLITSTIDHRDHPFILGCTN 272
>gi|328766513|gb|EGF76567.1| hypothetical protein BATDEDRAFT_18060 [Batrachochytrium dendrobatidis
JAM81]
Length=540
Score = 215 bits (547), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 123/290 (43%), Positives = 168/290 (58%), Gaps = 3/290 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
M++A T ++ T + F+++V ++++ S RF + R Y+A VV +RGT+PV + +
Sbjct 1 MSVALTPAQL-TEEQHAFDQEVLQVEQWWASDRFRLVTRPYSAADVVSKRGTLPVAY-PS 58
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
A + L+ A + + T+G P Q + M + ++ IY+ GW +S+ SS+ +P
Sbjct 59 NHQAKKLWNLLQNHKANKTASFTYGALDPVQVIQMGKY-LDTIYVSGWQSSSTASSSNEP 117
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
GPDLA YP+ VP+ L A L DR Q RL + RA P DF IIADA T
Sbjct 118 GPDLADYPMDTVPNKVEHLFLAQLFHDRKQRECRLTSTPEVRAKLPYTDFLRPIIADADT 177
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGG + L + FVE G G H+EDQ PGTKKCGH GKVLVP E I RL A R Q
Sbjct 178 GHGGITAIMKLAKMFVERGAAGIHLEDQAPGTKKCGHMAGKVLVPIMEHINRLIAVRLQF 237
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLA 290
DIM V +IVARTDAEAA L+ S D RD F+LG+T D+ + +A
Sbjct 238 DIMGVDNLIVARTDAEAATLLTSTIDTRDHYFILGSTNPDLKPLATVMIA 287
>gi|62122373|dbj|BAD93181.1| isocitrate lyase [Fomitopsis palustris]
Length=539
Score = 214 bits (546), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 117/267 (44%), Positives = 158/267 (60%), Gaps = 8/267 (2%)
Query 18 FEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDH---IVAREAAGAFYERLREL 74
F+ +VA ++++ RF + R YTA QVV +RGT+P+ + ++A++ + L +
Sbjct 8 FQAEVARVEQWWKDPRFNRVKRPYTAAQVVSKRGTLPISYPSDVLAKK----LWASLTQH 63
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
+ T+G P Q M + +E +Y+ GW +S+ SS+ +PGPDLA YP + VP+
Sbjct 64 YKNGTPSHTYGALDPVQVTQMAKY-LETVYVSGWQSSSTASSSNEPGPDLADYPSNTVPN 122
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L A L DR Q R +SE + A TP D+ IIADA TGHGG L +
Sbjct 123 KVEHLFMAQLFHDRKQAEARSNLSEAELAQTPVIDYLRPIIADADTGHGGLTATMKLAKM 182
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
FVE G G HIEDQ PGTKKCGH GKVLVP E I RL A R Q DIM V +++ARTD
Sbjct 183 FVEKGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRLQFDIMGVNNLVIARTD 242
Query 255 AEAANLIDSRADERDQPFLLGATKLDV 281
+EAA LI + DERD F+LG+T D+
Sbjct 243 SEAATLITTNVDERDHAFILGSTNPDL 269
>gi|54035734|sp|Q9HFN2.1|ACEA_PICJA RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase;
Short=Isocitratase
gi|10178959|emb|CAC08487.1| isocitrate lyase [Pichia jadinii]
Length=550
Score = 214 bits (545), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 118/303 (39%), Positives = 169/303 (56%), Gaps = 12/303 (3%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
++ FE++VAA ++++ R+ R+YTA+ +V++RGT+ + H + + A Y+ L E
Sbjct 12 QEAFEREVAAVEQWWKEPRWRKTTRIYTAKDIVQKRGTLQI-HYPSSDQAKKLYKLLEEH 70
Query 75 FAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPD 134
+ + TFG P M + ++ +Y+ GW +S+ S++ +P PDLA YP VP+
Sbjct 71 DRNKTASFTFGALDPIHVTQMAKY-LDTVYISGWQSSSTASTSNEPSPDLADYPYDTVPN 129
Query 135 DAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRR 194
L A L DR QH R +M+ +RA TP DF IIADA TGHGG + L +
Sbjct 130 KCEHLWFAQLFHDRKQHEERFRMTPEERAKTPYTDFLRPIIADADTGHGGITAIIKLTKL 189
Query 195 FVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTD 254
F+E G G HIEDQ PGTKKCGH GKVLVP E I RL A R DI + VARTD
Sbjct 190 FIERGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRTAADIFGSDLLCVARTD 249
Query 255 AEAANLIDSRADERDQPFLLGATKLDV-PSYKSCFLAMVRRF---------TNWASRSSM 304
+EAA L+ S D RD F++G+T D+ P + F A R +W ++ +
Sbjct 250 SEAATLLTSTIDHRDHYFIIGSTNKDLQPLSEVMFQAEQRGLLKVMLAAVEEDWTKKAGL 309
Query 305 VIF 307
+F
Sbjct 310 KLF 312
>gi|13123962|sp|Q9P8Q7.1|ACEA_CANAL RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase;
Short=Isocitratase
gi|6980002|gb|AAF34690.1|AF222905_1 isocitrate lyase [Candida albicans]
Length=550
Score = 214 bits (545), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 115/264 (44%), Positives = 158/264 (60%), Gaps = 4/264 (1%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
E DF+K+VA ++++ R+ R+Y+A + ++RGT+ ++H +++A F +L E
Sbjct 12 EADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLF--KLLET 69
Query 75 FAARKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVP 133
A K+++ TFG P M + +++IY+ GW S+ S++ +P PDLA YP+ VP
Sbjct 70 HDADKTVSFTFGALDPIHVAQMAKY-LDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVP 128
Query 134 DDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIR 193
+ L A L DR Q RL +S+ +RA TP DF IIADA TGHGG + L +
Sbjct 129 NKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTK 188
Query 194 RFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVART 253
F+E G G HIEDQ PGTKKCGH GKVLVP E I RL A R DI + VART
Sbjct 189 MFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVART 248
Query 254 DAEAANLIDSRADERDQPFLLGAT 277
D+EAA LI S D RD F++GAT
Sbjct 249 DSEAATLITSTIDHRDHYFIIGAT 272
>gi|294881042|ref|XP_002769215.1| Isocitrate lyase, putative [Perkinsus marinus ATCC 50983]
gi|239872493|gb|EER01933.1| Isocitrate lyase, putative [Perkinsus marinus ATCC 50983]
Length=543
Score = 214 bits (544), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 115/271 (43%), Positives = 155/271 (58%), Gaps = 12/271 (4%)
Query 17 DFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRG------TIPVDHIVAREAAGAFYER 70
+F DVA ++++ S R+ G RLY+A V RG P D + + +
Sbjct 12 EFASDVAEIKQWWQSERWTGKRRLYSAEDVARLRGQKAGRTKYPADAMSKK-----LWTS 66
Query 71 LRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLS 130
+E + TFG P Q M + ++ IY+ GW +S+ S++ +PGPD A YP +
Sbjct 67 FKEAQRTGGFLPTFGALDPVQVTQMAKY-LKTIYVSGWQSSSTASTSNEPGPDFADYPYN 125
Query 131 QVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRN 190
VP+ L RA + D+ QH R M+E +R ATPA D IIAD TGHGG V
Sbjct 126 TVPNKVDQLFRAQVFHDQKQHQERFGMTEAERQATPAVDHFAPIIADGDTGHGGLTAVMK 185
Query 191 LIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIV 250
L++ VE G G H+EDQ+PGTKKCGH GGKVLV + E I RL AAR D++ V IIV
Sbjct 186 LMKMMVERGAAGVHLEDQKPGTKKCGHMGGKVLVSTREHIDRLVAARLMTDVLGVETIIV 245
Query 251 ARTDAEAANLIDSRADERDQPFLLGATKLDV 281
ARTDAEAA L+D+ D RD F++GA+ +V
Sbjct 246 ARTDAEAATLLDTNIDSRDHSFIVGASNPNV 276
>gi|68487782|ref|XP_712232.1| hypothetical protein CaO19.6844 [Candida albicans SC5314]
gi|68487843|ref|XP_712202.1| hypothetical protein CaO19.14134 [Candida albicans SC5314]
gi|46433574|gb|EAK93009.1| hypothetical protein CaO19.14134 [Candida albicans SC5314]
gi|46433605|gb|EAK93039.1| hypothetical protein CaO19.6844 [Candida albicans SC5314]
gi|238879085|gb|EEQ42723.1| isocitrate lyase [Candida albicans WO-1]
Length=550
Score = 214 bits (544), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 115/264 (44%), Positives = 158/264 (60%), Gaps = 4/264 (1%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
E DF+K+VA ++++ R+ R+Y+A + ++RGT+ ++H +++A F +L E
Sbjct 12 EADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLF--KLLEK 69
Query 75 FAARKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVP 133
A K+++ TFG P M + +++IY+ GW S+ S++ +P PDLA YP+ VP
Sbjct 70 HDADKTVSFTFGALDPIHVAQMAKY-LDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVP 128
Query 134 DDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIR 193
+ L A L DR Q RL +S+ +RA TP DF IIADA TGHGG + L +
Sbjct 129 NKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTK 188
Query 194 RFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVART 253
F+E G G HIEDQ PGTKKCGH GKVLVP E I RL A R DI + VART
Sbjct 189 MFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVART 248
Query 254 DAEAANLIDSRADERDQPFLLGAT 277
D+EAA LI S D RD F++GAT
Sbjct 249 DSEAATLITSTIDHRDHYFIIGAT 272
>gi|241948743|ref|XP_002417094.1| isocitrate lyase, putative [Candida dubliniensis CD36]
gi|223640432|emb|CAX44684.1| isocitrate lyase, putative [Candida dubliniensis CD36]
Length=550
Score = 214 bits (544), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 115/264 (44%), Positives = 158/264 (60%), Gaps = 4/264 (1%)
Query 15 EQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLREL 74
E DF+K+VA ++++ R+ R+Y+A + ++RGT+ ++H +++A F +L E
Sbjct 12 EADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLF--KLLEK 69
Query 75 FAARKSIT-TFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVP 133
A K+++ TFG P M + +++IY+ GW S+ S++ +P PDLA YP+ VP
Sbjct 70 HDADKTVSFTFGALDPIHVAQMAKY-LDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVP 128
Query 134 DDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIR 193
+ L A L DR Q RL +S+ +RA TP DF IIADA TGHGG + L +
Sbjct 129 NKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTK 188
Query 194 RFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVART 253
F+E G G HIEDQ PGTKKCGH GKVLVP E I RL A R DI + VART
Sbjct 189 MFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVART 248
Query 254 DAEAANLIDSRADERDQPFLLGAT 277
D+EAA LI S D RD F++GAT
Sbjct 249 DSEAATLITSTIDHRDHYFIIGAT 272
>gi|146413757|ref|XP_001482849.1| isocitrate lyase [Meyerozyma guilliermondii ATCC 6260]
gi|146392548|gb|EDK40706.1| isocitrate lyase [Meyerozyma guilliermondii ATCC 6260]
Length=551
Score = 213 bits (541), Expect = 5e-53, Method: Compositional matrix adjust.
Identities = 118/282 (42%), Positives = 161/282 (58%), Gaps = 5/282 (1%)
Query 1 MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVA 60
M + DTE F F++ V ++++ R++ R+YTA + ++RGT+ +D+ +
Sbjct 1 MPYTKIDTEAEDQF---FKQQVQEIEQWWKQPRWSKTKRIYTAEAIAKKRGTLKIDYPSS 57
Query 61 REAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDP 120
+A F + L+E + + TFG P M + +++IY+ GW S+ S++ +P
Sbjct 58 NQAKKMF-KLLQEHEKNKTASFTFGALDPIHVAQMAKY-LDSIYVSGWQCSSTASTSNEP 115
Query 121 GPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGT 180
PDLA YP+ VP+ L A L DR Q RL +S+ +RA TP DF IIADA T
Sbjct 116 SPDLADYPMDTVPNKVEHLWFAQLFHDRKQREERLNLSKEERAKTPYIDFLRPIIADADT 175
Query 181 GHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQL 240
GHGG + L + FVE G G HIEDQ PGTKKCGH GKVLVP E I RL A R
Sbjct 176 GHGGITAIIKLTKMFVERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASA 235
Query 241 DIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVP 282
DI+ + VARTD+EAA LI S D RD F++GAT D P
Sbjct 236 DILGSDLLAVARTDSEAATLITSTIDHRDHYFVVGATNPDSP 277
Lambda K H
0.320 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 694383994300
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40