BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1916 Length=398 Score E Sequences producing significant alignments: (Bits) Value gi|15609053|ref|NP_216432.1| isocitrate lyase [Mycobacterium tub... 822 0.0 gi|254550932|ref|ZP_05141379.1| putative isocitrate lyase [Mycob... 822 0.0 gi|31793108|ref|NP_855601.1| isocitrate lyase [Mycobacterium bov... 822 0.0 gi|167970406|ref|ZP_02552683.1| putative isocitrate lyase aceA [... 821 0.0 gi|289554308|ref|ZP_06443518.1| LOW QUALITY PROTEIN: isocitrate ... 820 0.0 gi|340626925|ref|YP_004745377.1| putative isocitrate lyase ACEAB... 820 0.0 gi|289762070|ref|ZP_06521448.1| isocitrate lyase aceAb [Mycobact... 808 0.0 gi|240172596|ref|ZP_04751255.1| isocitrate lyase AceAb [Mycobact... 734 0.0 gi|183982825|ref|YP_001851116.1| isocitrate lyase AceAb [Mycobac... 734 0.0 gi|15828074|ref|NP_302337.1| isocitrate lyase [Mycobacterium lep... 728 0.0 gi|118618351|ref|YP_906683.1| isocitrate lyase AceAb [Mycobacter... 725 0.0 gi|296164945|ref|ZP_06847501.1| isocitrate lyase [Mycobacterium ... 724 0.0 gi|118464681|ref|YP_881969.1| isocitrate lyase [Mycobacterium av... 721 0.0 gi|41407741|ref|NP_960577.1| isocitrate lyase [Mycobacterium avi... 721 0.0 gi|342859571|ref|ZP_08716224.1| isocitrate lyase [Mycobacterium ... 712 0.0 gi|254821861|ref|ZP_05226862.1| isocitrate lyase [Mycobacterium ... 711 0.0 gi|333990644|ref|YP_004523258.1| isocitrate lyase AceAb [Mycobac... 668 0.0 gi|108797167|ref|YP_637364.1| isocitrate lyase [Mycobacterium sp... 663 0.0 gi|126432789|ref|YP_001068480.1| isocitrate lyase [Mycobacterium... 663 0.0 gi|120403959|ref|YP_953788.1| isocitrate lyase [Mycobacterium va... 660 0.0 gi|315444176|ref|YP_004077055.1| isocitrate lyase [Mycobacterium... 660 0.0 gi|145223847|ref|YP_001134525.1| isocitrate lyase [Mycobacterium... 658 0.0 gi|118471001|ref|YP_888007.1| isocitrate lyase [Mycobacterium sm... 656 0.0 gi|153004450|ref|YP_001378775.1| isocitrate lyase [Anaeromyxobac... 551 7e-155 gi|197122060|ref|YP_002134011.1| isocitrate lyase [Anaeromyxobac... 538 6e-151 gi|86158643|ref|YP_465428.1| isocitrate lyase [Anaeromyxobacter ... 538 7e-151 gi|220916830|ref|YP_002492134.1| isocitrate lyase [Anaeromyxobac... 538 8e-151 gi|294996828|ref|ZP_06802519.1| isocitrate lyase [Mycobacterium ... 530 2e-148 gi|13637587|sp|P46831.2|ACEA_MYCLE RecName: Full=Isocitrate lyas... 391 9e-107 gi|559906|emb|CAA86357.1| isocitrate lyase [Mycobacterium leprae] 391 9e-107 gi|294996827|ref|ZP_06802518.1| isocitrate lyase [Mycobacterium ... 290 3e-76 gi|71020403|ref|XP_760432.1| hypothetical protein UM04285.1 [Ust... 166 7e-39 gi|343425324|emb|CBQ68860.1| probable isocitrate lyase [Sporisor... 166 7e-39 gi|331218780|ref|XP_003322067.1| isocitrate lyase [Puccinia gram... 165 1e-38 gi|164656511|ref|XP_001729383.1| hypothetical protein MGL_3418 [... 163 5e-38 gi|224004182|ref|XP_002295742.1| isocitrate lyase [Thalassiosira... 162 7e-38 gi|328856720|gb|EGG05840.1| hypothetical protein MELLADRAFT_4870... 162 9e-38 gi|320165109|gb|EFW42008.1| isocitrate lyase [Capsaspora owczarz... 162 1e-37 gi|328766513|gb|EGF76567.1| hypothetical protein BATDEDRAFT_1806... 161 1e-37 gi|11131348|sp|Q9SE26.1|ACEA_DENCR RecName: Full=Isocitrate lyas... 161 2e-37 gi|219123724|ref|XP_002182169.1| predicted protein [Phaeodactylu... 160 3e-37 gi|70607900|ref|YP_256770.1| isocitrate lyase [Sulfolobus acidoc... 159 6e-37 gi|342320911|gb|EGU12849.1| Isocitrate lyase [Rhodotorula glutin... 157 2e-36 gi|302801596|ref|XP_002982554.1| hypothetical protein SELMODRAFT... 157 3e-36 gi|301111828|ref|XP_002904993.1| isocitrate lyase [Phytophthora ... 157 3e-36 gi|302798645|ref|XP_002981082.1| hypothetical protein SELMODRAFT... 157 4e-36 gi|164661854|ref|XP_001732049.1| hypothetical protein MGL_0642 [... 157 4e-36 gi|62122373|dbj|BAD93181.1| isocitrate lyase [Fomitopsis palustris] 157 4e-36 gi|323476618|gb|ADX81856.1| isocitrate lyase [Sulfolobus islandi... 156 5e-36 gi|18030082|gb|AAL56614.1|AF455253_1 isocitrate lyase [Cryptococ... 156 7e-36 >gi|15609053|ref|NP_216432.1| isocitrate lyase [Mycobacterium tuberculosis H37Rv] gi|148661724|ref|YP_001283247.1| isocitrate lyase AceAb [Mycobacterium tuberculosis H37Ra] gi|148823128|ref|YP_001287882.1| isocitrate lyase aceAb [Mycobacterium tuberculosis F11] 23 more sequence titles Length=398 Score = 822 bits (2123), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 >gi|254550932|ref|ZP_05141379.1| putative isocitrate lyase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|297634482|ref|ZP_06952262.1| isocitrate lyase [Mycobacterium tuberculosis KZN 4207] gi|297731470|ref|ZP_06960588.1| isocitrate lyase [Mycobacterium tuberculosis KZN R506] gi|313658803|ref|ZP_07815683.1| isocitrate lyase [Mycobacterium tuberculosis KZN V2475] Length=436 Score = 822 bits (2122), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 39 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 98 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 99 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 158 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 159 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 218 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 219 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 278 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 279 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 338 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 339 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 398 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 399 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 436 >gi|31793108|ref|NP_855601.1| isocitrate lyase [Mycobacterium bovis AF2122/97] gi|50953770|ref|NP_336424.2| isocitrate lyase [Mycobacterium tuberculosis CDC1551] gi|121637821|ref|YP_978044.1| putative isocitrate lyase aceA [Mycobacterium bovis BCG str. Pasteur 1173P2] 28 more sequence titles Length=766 Score = 822 bits (2122), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 369 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 428 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 429 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 488 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 489 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 548 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 549 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 608 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 609 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 668 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 669 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 728 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 729 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 766 >gi|167970406|ref|ZP_02552683.1| putative isocitrate lyase aceA [Mycobacterium tuberculosis H37Ra] gi|308369561|ref|ZP_07418259.2| isocitrate lyase aceAb [Mycobacterium tuberculosis SUMu002] gi|308327182|gb|EFP16033.1| isocitrate lyase aceAb [Mycobacterium tuberculosis SUMu002] Length=408 Score = 821 bits (2120), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 11 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 70 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 71 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 130 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 131 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 190 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 191 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 250 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 251 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 310 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 311 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 370 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 371 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 408 >gi|289554308|ref|ZP_06443518.1| LOW QUALITY PROTEIN: isocitrate lyase aceAb [Mycobacterium tuberculosis KZN 605] gi|289438940|gb|EFD21433.1| LOW QUALITY PROTEIN: isocitrate lyase aceAb [Mycobacterium tuberculosis KZN 605] Length=497 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 100 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 159 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 160 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 219 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 220 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 279 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 280 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 339 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 340 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 399 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 400 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 459 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 460 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 497 >gi|340626925|ref|YP_004745377.1| putative isocitrate lyase ACEAB (second part) [Mycobacterium canettii CIPT 140010059] gi|340005115|emb|CCC44264.1| putative isocitrate lyase ACEAB [second part] (isocitrase) (isocitratase) (ICL) [Mycobacterium canettii CIPT 140010059] Length=398 Score = 820 bits (2117), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/398 (99%), Positives = 397/398 (99%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAP EWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 1 MTYGEAVADVLEFGQSEGEPIGMAPAEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR Sbjct 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR Sbjct 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT Sbjct 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 >gi|289762070|ref|ZP_06521448.1| isocitrate lyase aceAb [Mycobacterium tuberculosis GM 1503] gi|289709576|gb|EFD73592.1| isocitrate lyase aceAb [Mycobacterium tuberculosis GM 1503] Length=392 Score = 808 bits (2086), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/392 (99%), Positives = 392/392 (100%), Gaps = 0/392 (0%) Query 7 VADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQ 66 +ADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQ Sbjct 1 MADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQ 60 Query 67 IRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNW 126 IRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNW Sbjct 61 IRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNW 120 Query 127 DTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRK 186 DTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRK Sbjct 121 DTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRK 180 Query 187 MRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEW 246 MRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEW Sbjct 181 MRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEW 240 Query 247 LAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVR 306 LAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVR Sbjct 241 LAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVR 300 Query 307 DQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEV 366 DQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEV Sbjct 301 DQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEV 360 Query 367 GEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 GEIIVAEVNHPRIAELLTPDRVALRKLITKEA Sbjct 361 GEIIVAEVNHPRIAELLTPDRVALRKLITKEA 392 >gi|240172596|ref|ZP_04751255.1| isocitrate lyase AceAb [Mycobacterium kansasii ATCC 12478] Length=766 Score = 734 bits (1896), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/398 (88%), Positives = 376/398 (95%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVL FG+SEGE +GM+PEEWRAFA RASL+AAR KAKELGADP WDCELAKT Sbjct 369 MTYGEAVADVLAFGESEGESVGMSPEEWRAFAGRASLYAARTKAKELGADPGWDCELAKT 428 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQ+RGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAE+PDQMLAYNL Sbjct 429 PEGYYQVRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEYPDQMLAYNL 488 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEM++FP ELGKMGFVFNFITYGGHQIDGVAAEEFAT+L+QDGMLAL Sbjct 489 SPSFNWDTTGMTDEEMKQFPVELGKMGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLAL 548 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVP+ Sbjct 549 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPK 608 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLA+WS HYQL +KLRVQLRP+RAGS+VLELGI+G D+ LANV+F PI+DR GR Sbjct 609 KLLEEWLALWSEHYQLGEKLRVQLRPRRAGSDVLELGIYGNDDEPLANVVFDPIKDRHGR 668 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV+YVTPT+DN YQTSKMKSHGIF+ Sbjct 669 SILTVRDQNTFAQKLRQKRLMTLIHLWLVHRFKADAVYYVTPTEDNQYQTSKMKSHGIFS 728 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EVNQ+VGEIIVAEVN PRI ELLT DRVALR+LITKE Sbjct 729 EVNQDVGEIIVAEVNKPRIEELLTADRVALRQLITKEG 766 >gi|183982825|ref|YP_001851116.1| isocitrate lyase AceAb [Mycobacterium marinum M] gi|183176151|gb|ACC41261.1| isocitrate lyase AceAb [Mycobacterium marinum M] Length=762 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/396 (89%), Positives = 374/396 (95%), Gaps = 0/396 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTY EAVA+VL FGQSEG+P+ M+PEEWR FAARASL+AAR KAKELG DP WDCELAKT Sbjct 365 MTYAEAVAEVLAFGQSEGDPVAMSPEEWRTFAARASLYAARQKAKELGVDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEM+RFPEELGKMGFVFNFITYGGHQIDGVA+EEFATALRQDGMLAL Sbjct 485 SPSFNWDTTGMTDEEMKRFPEELGKMGFVFNFITYGGHQIDGVASEEFATALRQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTKAMGKGSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLA+WS HYQL +KLRVQLRP+RAGS+VLELGI+G D++LANV+F PI+DR GR Sbjct 605 KLLEEWLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGNDDEQLANVVFDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV+YVTPT+DN YQTSKMKSHGIF+ Sbjct 665 SILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVTPTEDNQYQTSKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITK 396 EVNQ+VGEIIVAEVN PRI ELLT DRVALR+LITK Sbjct 725 EVNQDVGEIIVAEVNRPRIEELLTADRVALRQLITK 760 >gi|15828074|ref|NP_302337.1| isocitrate lyase [Mycobacterium leprae TN] gi|221230551|ref|YP_002503967.1| isocitrate lyase [Mycobacterium leprae Br4923] gi|13093628|emb|CAC30940.1| isocitrate lyase [Mycobacterium leprae] gi|219933658|emb|CAR72082.1| isocitrate lyase [Mycobacterium leprae Br4923] Length=798 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/398 (88%), Positives = 373/398 (94%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAV ++L+FG+SEGE IGM+PEEWR F RASL+AAR KAKELG DP WDCELAKT Sbjct 401 MTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELAKT 460 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGI YAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFP+QMLAYNL Sbjct 461 PEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLAYNL 520 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM+DEEM+RFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 521 SPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 580 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVP+ Sbjct 581 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPK 640 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLA+WS HYQL +KLRVQLRP+RAGS+VLELGI+G D++LANVI PI+DRRGR Sbjct 641 KLLEEWLALWSEHYQLGEKLRVQLRPRRAGSDVLELGIYGNGDEQLANVIVDPIKDRRGR 700 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIH WLVHRFKA V YVTPT+DNLYQTSKMKSHGIF+ Sbjct 701 SILQVRDQNTFAEKLRQKRLMTLIHFWLVHRFKADTVIYVTPTEDNLYQTSKMKSHGIFS 760 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EV QEVGEIIVAEVNHPR+ ELLTPDRVALR+LITKE Sbjct 761 EVYQEVGEIIVAEVNHPRLVELLTPDRVALRRLITKEG 798 >gi|118618351|ref|YP_906683.1| isocitrate lyase AceAb [Mycobacterium ulcerans Agy99] gi|118570461|gb|ABL05212.1| isocitrate lyase AceAb [Mycobacterium ulcerans Agy99] Length=762 Score = 725 bits (1871), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/396 (88%), Positives = 372/396 (94%), Gaps = 0/396 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTY EAVA+VL FGQSEG+P+ M+PEEWR FAARASL+AAR KAKE+G DP WDCELAKT Sbjct 365 MTYAEAVAEVLAFGQSEGDPVPMSPEEWRTFAARASLYAARQKAKEMGVDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDEEM+RFPEELGKMGFVFNFITYGGHQIDGVA+EEFATALRQDGMLAL Sbjct 485 SPSFNWDTTGMTDEEMKRFPEELGKMGFVFNFITYGGHQIDGVASEEFATALRQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLV GPRSDAAL ASSGRTATTKAMGKGSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVAGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEE LA+WS HYQL +KLRVQLRP+RAGS+VLELGI+G D++LANV+F PI+DR GR Sbjct 605 KLLEERLALWSDHYQLGEKLRVQLRPRRAGSDVLELGIYGNDDEQLANVVFDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV+YVTPT+DN YQTSKMKSHGIF+ Sbjct 665 SILTVRDQNTFAHKLRQKRLMTLIHLWLVHRFKADAVYYVTPTEDNQYQTSKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITK 396 EVNQ+VGEIIVAEVN PRI ELLT DRVALR+LITK Sbjct 725 EVNQDVGEIIVAEVNRPRIEELLTADRVALRQLITK 760 >gi|296164945|ref|ZP_06847501.1| isocitrate lyase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899787|gb|EFG79237.1| isocitrate lyase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=763 Score = 724 bits (1869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/398 (88%), Positives = 370/398 (93%), Gaps = 1/398 (0%) Query 1 MTYGEAVADVLEFGQSE-GEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAK 59 MTYGEAVA+VLEFG+SE EP GM+P EWR FA RASL+AAR KA++LG DPPWDCELAK Sbjct 365 MTYGEAVAEVLEFGESEEDEPRGMSPAEWRKFAERASLYAAREKARQLGVDPPWDCELAK 424 Query 60 TPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYN 119 TPEGYYQIRGGIPYAI KSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYN Sbjct 425 TPEGYYQIRGGIPYAIVKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYN 484 Query 120 LSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLA 179 LSPSFNWDTTGMTD+EM+RFPEELGKMGFVFNFITYGGHQIDGVAAEEFA +L+QDGMLA Sbjct 485 LSPSFNWDTTGMTDDEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFAASLKQDGMLA 544 Query 180 LARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVP 239 LARLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTKAMGKGSTQHQHLVQTEVP Sbjct 545 LARLQRKMRLVESPYRTPQTLVGGPRSDAALQASSGRTATTKAMGKGSTQHQHLVQTEVP 604 Query 240 RKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRG 299 +KLLEEWLA+WS HYQL +KLRV LRP+R GS+VL LGIHG D++LANV+F PI+DR G Sbjct 605 KKLLEEWLALWSEHYQLGEKLRVSLRPRRPGSDVLVLGIHGNGDEQLANVVFDPIKDRHG 664 Query 300 RTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIF 359 R+IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV+YVTPT+DN YQTSKMKSHGIF Sbjct 665 RSILTVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVYYVTPTEDNQYQTSKMKSHGIF 724 Query 360 TEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 TEVNQEVGEIIVAEVN PRI ELL PDRVALRKLITKE Sbjct 725 TEVNQEVGEIIVAEVNRPRIEELLKPDRVALRKLITKE 762 >gi|118464681|ref|YP_881969.1| isocitrate lyase [Mycobacterium avium 104] gi|254775261|ref|ZP_05216777.1| isocitrate lyase [Mycobacterium avium subsp. avium ATCC 25291] gi|118165968|gb|ABK66865.1| isocitrate lyase [Mycobacterium avium 104] Length=762 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/397 (88%), Positives = 375/397 (95%), Gaps = 0/397 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVA+VLEF SEGEP M+ +EWRAFAARASL++A+AKAKELG DP WDCELAKT Sbjct 365 MTYGEAVAEVLEFAASEGEPADMSADEWRAFAARASLYSAKAKAKELGFDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHAEFPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAEFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDE+M++FPEELGKMGFVFNFITYGGHQIDGVAAEEFAT+L+QDGMLAL Sbjct 485 SPSFNWDTTGMTDEQMKQFPEELGKMGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMG+GSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGEGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWS +Y L +KLRVQLRP+RAGS+VLELGI+G+ D++LANV+ PI+DR GR Sbjct 605 KLLEEWLAMWSENYHLGEKLRVQLRPRRAGSDVLELGIYGDGDEQLANVVVDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV YVTPT+DNLYQTSKMKSHGIF+ Sbjct 665 SILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVIYVTPTEDNLYQTSKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 EV QEVGEIIVAEVN PRIAELL PDRVALRKLITKE Sbjct 725 EVYQEVGEIIVAEVNRPRIAELLQPDRVALRKLITKE 761 >gi|41407741|ref|NP_960577.1| isocitrate lyase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396094|gb|AAS03960.1| AceAb [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457402|gb|EGO36411.1| isocitrate lyase [Mycobacterium avium subsp. paratuberculosis S397] Length=762 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/397 (88%), Positives = 375/397 (95%), Gaps = 0/397 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVA+VLEF SEGEP M+ +EWRAFAARASL++A+AKAKELG DP WDCELAKT Sbjct 365 MTYGEAVAEVLEFAASEGEPADMSADEWRAFAARASLYSAKAKAKELGFDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHAEFPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAEFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDE+M++FPEELGKMGFVFNFITYGGHQIDGVAAEEFAT+L+QDGMLAL Sbjct 485 SPSFNWDTTGMTDEQMKQFPEELGKMGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMG+GSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGEGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWS +Y L +KLRVQLRP+RAGS+VLELGI+G+ D++LANV+ PI+DR GR Sbjct 605 KLLEEWLAMWSENYHLGEKLRVQLRPRRAGSDVLELGIYGDGDEQLANVVVDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV YVTPT+DNLYQTSKMKSHGIF+ Sbjct 665 SILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVIYVTPTEDNLYQTSKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 EV QEVGEIIVAEVN PRIAELL PDRVALRKLITKE Sbjct 725 EVYQEVGEIIVAEVNRPRIAELLQPDRVALRKLITKE 761 >gi|342859571|ref|ZP_08716224.1| isocitrate lyase [Mycobacterium colombiense CECT 3035] gi|342132703|gb|EGT85923.1| isocitrate lyase [Mycobacterium colombiense CECT 3035] Length=762 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/397 (86%), Positives = 370/397 (94%), Gaps = 0/397 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVA+VLEF SEGEP M+ +EWRAFAARASL++A+ KAKELG DP WDCEL+KT Sbjct 365 MTYGEAVAEVLEFDASEGEPADMSVDEWRAFAARASLYSAKTKAKELGVDPGWDCELSKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHAEFPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAEFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDE+M++FPEELGKMGFVFNFITYGGHQIDGVAAEEFAT+L+QDGMLAL Sbjct 485 SPSFNWDTTGMTDEQMKQFPEELGKMGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTKAMG+GSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGPRSDAALTASSGRTATTKAMGEGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWS +Y L +KLRVQLRP+RAGS+VLELGI+G D++LANV+ PI+DR GR Sbjct 605 KLLEEWLAMWSENYNLGEKLRVQLRPRRAGSDVLELGIYGNDDEQLANVVVDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA AV YVTPT+DN YQT KMKSHGIF+ Sbjct 665 SILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADAVIYVTPTEDNQYQTEKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 EV QEVGEIIVAEVN PRIAELL PDRVALRKLITKE Sbjct 725 EVYQEVGEIIVAEVNRPRIAELLQPDRVALRKLITKE 761 >gi|254821861|ref|ZP_05226862.1| isocitrate lyase [Mycobacterium intracellulare ATCC 13950] Length=762 Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/398 (86%), Positives = 368/398 (93%), Gaps = 0/398 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVL F SEGEP M+ EEWR FAA ASL++ARAKAKELG DP WDCEL+KT Sbjct 365 MTYGEAVADVLAFAASEGEPADMSAEEWREFAATASLYSARAKAKELGVDPGWDCELSKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFAD+LWMETKTADL DARQFA+AIHA+FPDQMLAYNL Sbjct 425 PEGYYQIRGGIPYAIAKSLAAAPFADLLWMETKTADLDDARQFADAIHAKFPDQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDE+M++FPEELGKMGFVFNFITYGGHQIDGVAAEEFAT+L+QDGMLAL Sbjct 485 SPSFNWDTTGMTDEQMKQFPEELGKMGFVFNFITYGGHQIDGVAAEEFATSLQQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTK+MG+GSTQHQHLVQTEVP+ Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGPRSDAALTASSGRTATTKSMGEGSTQHQHLVQTEVPK 604 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLAMWS +Y L +KLRVQLRP+RAGS+VLELGI+G D++LANV+ PI+DR GR Sbjct 605 KLLEEWLAMWSENYDLGEKLRVQLRPRRAGSDVLELGIYGNDDEQLANVVVDPIKDRHGR 664 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF +LRQKRLMTLIHLWLVHRFKA V YVTPT+DNLYQTSKMKSHGIF+ Sbjct 665 SILQVRDQNTFAEKLRQKRLMTLIHLWLVHRFKADGVIYVTPTEDNLYQTSKMKSHGIFS 724 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA 398 EV QEVGEIIVAEVN PRIAELL PDRVALRKLITKE Sbjct 725 EVYQEVGEIIVAEVNQPRIAELLKPDRVALRKLITKEG 762 >gi|333990644|ref|YP_004523258.1| isocitrate lyase AceAb [Mycobacterium sp. JDM601] gi|333486612|gb|AEF36004.1| isocitrate lyase AceAb [Mycobacterium sp. JDM601] Length=765 Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/397 (80%), Positives = 351/397 (89%), Gaps = 0/397 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MT+G+AVA++LEF + EGEP M+ EWR FAARA L+ AR KA EL ADP WDCE AKT Sbjct 368 MTFGDAVAEMLEFAEREGEPKDMSAAEWREFAARAPLYTARQKATELHADPGWDCERAKT 427 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGY+Q+RGGIPYAIAKSLAAAPFAD+LWMETKTADL DAR+FAEAIHA +PDQMLAYNL Sbjct 428 PEGYFQVRGGIPYAIAKSLAAAPFADLLWMETKTADLDDAREFAEAIHAVYPDQMLAYNL 487 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGMTDE+MR FP ELGKMGFVFNFITYGGHQ+DGVA+EEFA L QDGMLAL Sbjct 488 SPSFNWDTTGMTDEQMRAFPAELGKMGFVFNFITYGGHQVDGVASEEFAATLLQDGMLAL 547 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMG GSTQHQHLVQTEVP+ Sbjct 548 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGAGSTQHQHLVQTEVPK 607 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 KLLEEWLA+W+ HYQL ++LRV LRP R GS+VLELGI+G+ D+KLANVI PI+DR GR Sbjct 608 KLLEEWLALWAEHYQLGERLRVHLRPTRPGSDVLELGIYGDDDEKLANVIVDPIKDRHGR 667 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNTF + RQKRLM L HLWL+HRFKA AVHYVTPT DNLYQT KMK+HG+F+ Sbjct 668 SILTVRDQNTFAEKFRQKRLMDLTHLWLIHRFKAAAVHYVTPTQDNLYQTEKMKAHGMFS 727 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 V+QEVGEIIVA+VN PRI ELL PDR AL KLI+KE Sbjct 728 SVHQEVGEIIVADVNQPRIDELLAPDRAALGKLISKE 764 >gi|108797167|ref|YP_637364.1| isocitrate lyase [Mycobacterium sp. MCS] gi|119866252|ref|YP_936204.1| isocitrate lyase [Mycobacterium sp. KMS] gi|108767586|gb|ABG06308.1| isocitrate lyase [Mycobacterium sp. MCS] gi|119692341|gb|ABL89414.1| isocitrate lyase [Mycobacterium sp. KMS] Length=765 Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/399 (81%), Positives = 354/399 (89%), Gaps = 3/399 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TY E VA LEF + +GE M +EW FA RASL+ A KA+ELG D WDCELAKTP Sbjct 366 TYAETVAARLEFAEGDGEAYAMGVDEWTQFAKRASLYTAGKKARELGVDVDWDCELAKTP 425 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAK LAAAPFADILWMETKTADLADAR+FAEAIHAE+PD+MLAYNLS Sbjct 426 EGYYQLRGGIPYAIAKQLAAAPFADILWMETKTADLADAREFAEAIHAEYPDKMLAYNLS 485 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGMTD+EMR FPEELGKMGFVFNFITYGGHQ+DGVA+EEFATALRQDGMLALA Sbjct 486 PSFNWDTTGMTDDEMRAFPEELGKMGFVFNFITYGGHQVDGVASEEFATALRQDGMLALA 545 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTKAMGKGSTQHQHLVQTEVP+K Sbjct 546 RLQRKMRLVESPYRTPQTLVGGPRSDAALLASSGRTATTKAMGKGSTQHQHLVQTEVPKK 605 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESD---DKLANVIFQPIQDRR 298 LLE+WLAMWS HYQL +KLRVQLRP+RAG EVLELGI+GE D +KLA+V+ PI+DR Sbjct 606 LLEDWLAMWSEHYQLGEKLRVQLRPRRAGGEVLELGIYGERDGGEEKLADVLVDPIKDRY 665 Query 299 GRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGI 358 GR+IL VRDQNT+ +LR+KRLMTL+HLWLVHRFKA AV+YVTPTDDN+YQT KMKSHGI Sbjct 666 GRSILTVRDQNTYAEKLRKKRLMTLVHLWLVHRFKADAVYYVTPTDDNVYQTEKMKSHGI 725 Query 359 FTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 F++V+++VGEIIVAEVN RI ELL PDR AL +LI KE Sbjct 726 FSDVHKDVGEIIVAEVNRARIEELLAPDREALGRLIRKE 764 >gi|126432789|ref|YP_001068480.1| isocitrate lyase [Mycobacterium sp. JLS] gi|126232589|gb|ABN95989.1| isocitrate lyase [Mycobacterium sp. JLS] Length=765 Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/399 (81%), Positives = 354/399 (89%), Gaps = 3/399 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TY E VA LEF + +GE M +EW FA RASL+ A KA+ELG D WDCELAKTP Sbjct 366 TYAETVAARLEFAEGDGEAYAMGVDEWTQFAKRASLYTAGKKARELGVDVDWDCELAKTP 425 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAK LAAAPFADILWMETKTADLADAR+FAEAIHAE+PD+MLAYNLS Sbjct 426 EGYYQLRGGIPYAIAKQLAAAPFADILWMETKTADLADAREFAEAIHAEYPDKMLAYNLS 485 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGMTD+EMR FPEELGKMGFVFNFITYGGHQ+DGVA+EEFATALRQDGMLALA Sbjct 486 PSFNWDTTGMTDDEMRAFPEELGKMGFVFNFITYGGHQVDGVASEEFATALRQDGMLALA 545 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAAL ASSGRTATTKAMGKGSTQHQHLVQTEVP+K Sbjct 546 RLQRKMRLVESPYRTPQTLVGGPRSDAALLASSGRTATTKAMGKGSTQHQHLVQTEVPKK 605 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESD---DKLANVIFQPIQDRR 298 LLE+WLAMWS HYQL +KLRVQLRP+RAG EVLELGI+GE D +KLA+V+ PI+DR Sbjct 606 LLEDWLAMWSEHYQLGEKLRVQLRPRRAGGEVLELGIYGERDSGEEKLADVLVDPIKDRY 665 Query 299 GRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGI 358 GR+IL VRDQNT+ +LR+KRLMTL+HLWLVHRFKA AV+YVTPTDDN+YQT KMKSHGI Sbjct 666 GRSILTVRDQNTYAEKLRKKRLMTLVHLWLVHRFKADAVYYVTPTDDNVYQTEKMKSHGI 725 Query 359 FTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 F++V+++VGEIIVAEVN RI ELL PDR AL +LI KE Sbjct 726 FSDVHKDVGEIIVAEVNRARIEELLAPDREALGRLIRKE 764 >gi|120403959|ref|YP_953788.1| isocitrate lyase [Mycobacterium vanbaalenii PYR-1] gi|119956777|gb|ABM13782.1| isocitrate lyase [Mycobacterium vanbaalenii PYR-1] Length=766 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/396 (79%), Positives = 355/396 (90%), Gaps = 0/396 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TYGEAVA++LEF + EGEP M+ +WR FA RA L+ AR KAKELGAD WDCE KTP Sbjct 370 TYGEAVAELLEFREREGEPSSMSVADWRMFAERAPLYTAREKAKELGADVAWDCERVKTP 429 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHA +PD+MLAYNLS Sbjct 430 EGYYQVRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAVYPDKMLAYNLS 489 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGM+DEEMR FPEE+GKMGFVFNFITYGGHQ+DGVA+EEFAT+LRQ+GMLALA Sbjct 490 PSFNWDTTGMSDEEMRTFPEEIGKMGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALA 549 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTK+MGKGSTQHQHLVQTEVP+K Sbjct 550 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLVQTEVPKK 609 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRT 301 LLEEWL +WS HYQL ++L VQLRP+RAGS+VL+L I G+S++ LANV+ PI+DR GR+ Sbjct 610 LLEEWLGLWSEHYQLPERLHVQLRPRRAGSDVLDLQILGDSEEPLANVVVDPIKDRHGRS 669 Query 302 ILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTE 361 IL VRDQNTF ++RQKRLM LIHLWL+HRFKA+ V+YVTPT+DN+YQT KMKSHGIF++ Sbjct 670 ILTVRDQNTFAEQMRQKRLMDLIHLWLIHRFKAEIVYYVTPTEDNIYQTEKMKSHGIFSD 729 Query 362 VNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 V QEVGEIIVA+VN RI ELL PDR AL +LI K+ Sbjct 730 VYQEVGEIIVADVNQARIDELLAPDRKALIRLINKQ 765 >gi|315444176|ref|YP_004077055.1| isocitrate lyase [Mycobacterium sp. Spyr1] gi|315262479|gb|ADT99220.1| isocitrate lyase [Mycobacterium sp. Spyr1] Length=762 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/396 (80%), Positives = 355/396 (90%), Gaps = 0/396 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TYGEAVA++LEF + EGEP M+ +WR FA RA L+ AR KAKELGAD WDCE KTP Sbjct 366 TYGEAVAELLEFREREGEPSPMSVAQWREFAERAPLYTAREKAKELGADVAWDCERVKTP 425 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHA +PD+MLAYNLS Sbjct 426 EGYYQVRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAVYPDKMLAYNLS 485 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGMTDEEMR FPEE+GKMGFVFNFITYGGHQ+DGVA+EEFAT+LRQ+GMLALA Sbjct 486 PSFNWDTTGMTDEEMRAFPEEIGKMGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALA 545 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTK+MGKGSTQHQHLVQTEVP+K Sbjct 546 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLVQTEVPKK 605 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRT 301 LLEEWLA+WS H +L ++L VQLRP+RAGS+VL+L I G+S+D LANV+ PI+DR GR+ Sbjct 606 LLEEWLALWSEHNKLPERLHVQLRPRRAGSDVLDLQILGDSEDPLANVVVDPIKDRHGRS 665 Query 302 ILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTE 361 IL VRDQNTF LRQKRLM +IHLWL+HRFKA+ V+YVTPT+DN+YQT KMKSHGIF++ Sbjct 666 ILTVRDQNTFAEHLRQKRLMDVIHLWLIHRFKAEIVYYVTPTEDNIYQTEKMKSHGIFSD 725 Query 362 VNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 V QEVGEIIVA+VN RI ELL PDR AL +LITK+ Sbjct 726 VYQEVGEIIVADVNQARIDELLAPDREALTRLITKQ 761 >gi|145223847|ref|YP_001134525.1| isocitrate lyase [Mycobacterium gilvum PYR-GCK] gi|145216333|gb|ABP45737.1| isocitrate lyase [Mycobacterium gilvum PYR-GCK] Length=762 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/396 (80%), Positives = 355/396 (90%), Gaps = 0/396 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TYGEAVA++LEF + EGEP M+ +WR FA RA L+ AR KAKELGAD WDCE KTP Sbjct 366 TYGEAVAELLEFREREGEPSPMSVAQWREFAERAPLYTAREKAKELGADVAWDCERVKTP 425 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHA +PD+MLAYNLS Sbjct 426 EGYYQVRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAVYPDKMLAYNLS 485 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGMTDEEMR FPEE+GKMGFVFNFITYGGHQ+DGVA+EEFAT+LRQ+GMLALA Sbjct 486 PSFNWDTTGMTDEEMRAFPEEIGKMGFVFNFITYGGHQVDGVASEEFATSLRQEGMLALA 545 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTK+MGKGSTQHQHL+QTEVP+K Sbjct 546 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKSMGKGSTQHQHLLQTEVPKK 605 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRT 301 LLEEWLA+WS H +L ++L VQLRP+RAGS+VL+L I G+S+D LANV+ PI+DR GR+ Sbjct 606 LLEEWLALWSEHNKLPERLHVQLRPRRAGSDVLDLQILGDSEDPLANVVVDPIKDRHGRS 665 Query 302 ILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTE 361 IL VRDQNTF LRQKRLM +IHLWL+HRFKA+ V+YVTPT+DN+YQT KMKSHGIF++ Sbjct 666 ILTVRDQNTFAEHLRQKRLMDVIHLWLIHRFKAEIVYYVTPTEDNIYQTEKMKSHGIFSD 725 Query 362 VNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 V QEVGEIIVA+VN RI ELL PDR AL +LITK+ Sbjct 726 VYQEVGEIIVADVNQARIDELLAPDREALTRLITKQ 761 >gi|118471001|ref|YP_888007.1| isocitrate lyase [Mycobacterium smegmatis str. MC2 155] gi|118172288|gb|ABK73184.1| isocitrate lyase [Mycobacterium smegmatis str. MC2 155] Length=769 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/399 (79%), Positives = 351/399 (88%), Gaps = 3/399 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TYGEAVA+V+EF + EGE + M+ EWR FA RA L+ A KA+ELG D WDCE AKTP Sbjct 370 TYGEAVAEVIEFREREGESVAMSAAEWREFATRAPLYTATNKARELGVDVAWDCEPAKTP 429 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EGYYQ+RGGIPYAIAKSLAAAPFADILWMETKTADLADA+QFA+AIHA +PDQMLAYNLS Sbjct 430 EGYYQVRGGIPYAIAKSLAAAPFADILWMETKTADLADAKQFADAIHAVYPDQMLAYNLS 489 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGMTD+EMR FPEELGKMGFVFNFITYGGHQ+DGVA EEFAT+LRQ+GMLALA Sbjct 490 PSFNWDTTGMTDDEMRAFPEELGKMGFVFNFITYGGHQVDGVACEEFATSLRQEGMLALA 549 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVP+K Sbjct 550 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPKK 609 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGE---SDDKLANVIFQPIQDRR 298 LLEEWLAMWS HY L +KL VQLRP+RAGS+VL+L I GE D LANV+ PI+DR Sbjct 610 LLEEWLAMWSEHYGLPEKLHVQLRPRRAGSDVLDLQILGEGGDGTDPLANVVVDPIKDRH 669 Query 299 GRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGI 358 GR+IL VRDQNTF ++R+KRLM LIHLWL+HRFKA+ V+YVTPT+DN+YQT KMK+HGI Sbjct 670 GRSILTVRDQNTFAEQMRKKRLMDLIHLWLIHRFKAEIVYYVTPTEDNIYQTEKMKAHGI 729 Query 359 FTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 F++V QEVGEIIVA+VN PRI ELL DR AL +LI KE Sbjct 730 FSDVYQEVGEIIVADVNKPRIEELLASDREALGRLIRKE 768 >gi|153004450|ref|YP_001378775.1| isocitrate lyase [Anaeromyxobacter sp. Fw109-5] gi|152028023|gb|ABS25791.1| isocitrate lyase [Anaeromyxobacter sp. Fw109-5] Length=750 Score = 551 bits (1420), Expect = 7e-155, Method: Compositional matrix adjust. Identities = 266/396 (68%), Positives = 311/396 (79%), Gaps = 0/396 (0%) Query 2 TYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTP 61 TY EAV + + F + EG+P M EW AFA RA + AR +A+ +G D WDCE AKTP Sbjct 355 TYAEAVGEAIGFREHEGDPAAMGKAEWLAFAERAPFYKARQRARAIGLDVTWDCEHAKTP 414 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 +GYYQ+RGGI YAIAKSLAAAPFAD+LWMETKTADL DA++FA+A+HA +PD+MLAYNLS Sbjct 415 DGYYQVRGGIDYAIAKSLAAAPFADLLWMETKTADLHDAKRFADAVHAAYPDKMLAYNLS 474 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA 181 PSFNWDTTGM DE+MRRFPEELGK+GFVFNFITYGGHQIDG+AAEEFATALRQDGMLALA Sbjct 475 PSFNWDTTGMDDEQMRRFPEELGKLGFVFNFITYGGHQIDGLAAEEFATALRQDGMLALA 534 Query 182 RLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRK 241 RLQRK RL+ES YRTPQTLVGGPR+DA L + SGRT+TTKAMG+GSTQ QHLVQTEVP + Sbjct 535 RLQRKFRLLESGYRTPQTLVGGPRADAGLMSISGRTSTTKAMGQGSTQVQHLVQTEVPPR 594 Query 242 LLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRT 301 LLEEW+ W H+ + KLR LRP S++LEL + +K NVIF I DRRGR+ Sbjct 595 LLEEWVDAWREHHAIPGKLRATLRPHTGESDLLELALTSADGEKKLNVIFASIHDRRGRS 654 Query 302 ILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTE 361 IL VRDQN F A LRQKRLMTL L+L HR+K +VH+VTPT DN Q MK+ G+F Sbjct 655 ILSVRDQNNFDARLRQKRLMTLALLFLFHRYKVDSVHFVTPTADNQRQAEGMKAQGLFGT 714 Query 362 VNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKE 397 V QEVG IIVA+V R+ ELL PDR AL+ LI ++ Sbjct 715 VVQEVGRIIVADVAKDRVKELLAPDRAALKALIARQ 750 >gi|197122060|ref|YP_002134011.1| isocitrate lyase [Anaeromyxobacter sp. K] gi|196171909|gb|ACG72882.1| isocitrate lyase [Anaeromyxobacter sp. K] Length=748 Score = 538 bits (1386), Expect = 6e-151, Method: Compositional matrix adjust. Identities = 264/394 (68%), Positives = 311/394 (79%), Gaps = 0/394 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 TY EAVA + F + EGE M +EW AFAARA + AR KA+ +G + PWDCE AKT Sbjct 353 CTYAEAVAQAIAFREHEGEHPTMRRDEWMAFAARAPFYRAREKARAMGIETPWDCEHAKT 412 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 P+GYYQ+RGGI YAI KSLAAAPFAD+LWMETKTADLADAR+FA+AIHA PD+MLAYNL Sbjct 413 PDGYYQVRGGIDYAIQKSLAAAPFADLLWMETKTADLADARRFADAIHAVHPDKMLAYNL 472 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM DE+MRRFPEELGK+G+VF+FITYGGHQIDG+AAEEFATALR+DGMLAL Sbjct 473 SPSFNWDTTGMDDEQMRRFPEELGKLGYVFDFITYGGHQIDGLAAEEFATALREDGMLAL 532 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRK RL+ES YRTPQTLVGGPR DAAL A SGRTATTKAMG+GSTQHQHLVQTEVP Sbjct 533 ARLQRKFRLLESGYRTPQTLVGGPRLDAALMAVSGRTATTKAMGQGSTQHQHLVQTEVPP 592 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 +LLE+WL +W + ++ KLR LRP AGS++LEL + ++ +V F I DRRGR Sbjct 593 RLLEDWLDLWRERHGVQGKLRAALRPVTAGSDLLELVVTSADGERKLDVTFASITDRRGR 652 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNT LR+KRLMTL L+L HR++ + HYVTPT+DN Q MK+ G+F Sbjct 653 SILSVRDQNTHDLALRRKRLMTLAQLFLFHRYRVDSAHYVTPTEDNQRQAEGMKALGLFR 712 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLI 394 V QEVGEIIVA+V+ R+ L D VAL+ L+ Sbjct 713 SVAQEVGEIIVADVDRARVKALAARDHVALKALL 746 >gi|86158643|ref|YP_465428.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-C] gi|85775154|gb|ABC81991.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-C] Length=749 Score = 538 bits (1386), Expect = 7e-151, Method: Compositional matrix adjust. Identities = 262/396 (67%), Positives = 309/396 (79%), Gaps = 0/396 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 TY EAV + F + EGE M +EW AFAARA + AR KA+ +G DPPWDCE AKT Sbjct 353 CTYAEAVGQAIAFREHEGERPAMRRDEWMAFAARAPFYRAREKARAMGIDPPWDCEHAKT 412 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 P+GYYQ+RGGI YAI KSLAAAPFAD+LWMETKTADLADAR+FA+AIHA PD+MLAYNL Sbjct 413 PDGYYQVRGGIDYAIQKSLAAAPFADLLWMETKTADLADARRFADAIHAVHPDKMLAYNL 472 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM D++MRRFPEELGK+GFVF+FITYGGHQIDG+AAEEFATALR+DGMLAL Sbjct 473 SPSFNWDTTGMDDDQMRRFPEELGKLGFVFDFITYGGHQIDGLAAEEFATALREDGMLAL 532 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRK RL+ES YRTPQTLVGGPR DAAL A SGRTATTKAMG+GSTQHQHLVQTEVP Sbjct 533 ARLQRKFRLLESGYRTPQTLVGGPRLDAALMAVSGRTATTKAMGQGSTQHQHLVQTEVPP 592 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 +LL++WL +W + + +L LRP AGS++LEL + ++ +V F I DRRGR Sbjct 593 RLLDDWLDLWRDQHGVPGRLHATLRPVTAGSDLLELVVTSADGERKLDVTFASITDRRGR 652 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNT LR+KRLMTL L+L HR++ + HYVTPT+DN Q MK+ G+F Sbjct 653 SILSVRDQNTHDLSLRRKRLMTLAQLFLFHRYRVDSAHYVTPTEDNQRQAEGMKALGLFR 712 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITK 396 V QEVGEIIVA+V+ R+ L D AL+ LI + Sbjct 713 SVAQEVGEIIVADVDRARVKALAARDHAALKALIAR 748 >gi|220916830|ref|YP_002492134.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-1] gi|219954684|gb|ACL65068.1| isocitrate lyase [Anaeromyxobacter dehalogenans 2CP-1] Length=748 Score = 538 bits (1385), Expect = 8e-151, Method: Compositional matrix adjust. Identities = 264/394 (68%), Positives = 310/394 (79%), Gaps = 0/394 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 TY EAVA + F + EGE M +EW AFAARA + AR KA+ +G D PWDCE AKT Sbjct 353 CTYAEAVAQAIAFREHEGEHPTMRRDEWMAFAARAPFYRAREKARAMGIDTPWDCEHAKT 412 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 P+GYYQ+RGGI YAI KSLAAAPFAD+LWMETKTADLADAR+FA+AIHA PD+MLAYNL Sbjct 413 PDGYYQVRGGIDYAIQKSLAAAPFADLLWMETKTADLADARRFADAIHAVHPDKMLAYNL 472 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM DE+MRRFPEELGK+G+VF+FITYGGHQIDG+AAEEFATALR+DGMLAL Sbjct 473 SPSFNWDTTGMDDEQMRRFPEELGKLGYVFDFITYGGHQIDGLAAEEFATALREDGMLAL 532 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPR 240 ARLQRK RL+ES YRTPQTLVGGPR DAAL A SGRTATTKAMG+GSTQHQHLVQTEVP Sbjct 533 ARLQRKFRLLESGYRTPQTLVGGPRLDAALMAVSGRTATTKAMGQGSTQHQHLVQTEVPP 592 Query 241 KLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGR 300 +LLE+WL +W + ++ KLR LRP AGS++LEL + ++ +V F I DRRGR Sbjct 593 RLLEDWLDLWRERHGVQGKLRAALRPVTAGSDLLELVVTSADGERKLDVTFASITDRRGR 652 Query 301 TILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFT 360 +IL VRDQNT LR+KRLMTL L+L HR++ + HYVTPT+DN Q MK+ G+F Sbjct 653 SILSVRDQNTHDLALRRKRLMTLAQLFLFHRYRVDSAHYVTPTEDNQRQAEGMKALGLFR 712 Query 361 EVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLI 394 V QEVG IIVA+V+ R+ L D VAL+ L+ Sbjct 713 SVAQEVGAIIVADVDRARVKALAARDHVALKALL 746 >gi|294996828|ref|ZP_06802519.1| isocitrate lyase [Mycobacterium tuberculosis 210] Length=258 Score = 530 bits (1365), Expect = 2e-148, Method: Compositional matrix adjust. Identities = 258/258 (100%), Positives = 258/258 (100%), Gaps = 0/258 (0%) Query 141 EELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTL 200 EELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTL Sbjct 1 EELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTL 60 Query 201 VGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKL 260 VGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKL Sbjct 61 VGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKL 120 Query 261 RVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRL 320 RVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRL Sbjct 121 RVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRL 180 Query 321 MTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIA 380 MTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIA Sbjct 181 MTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIA 240 Query 381 ELLTPDRVALRKLITKEA 398 ELLTPDRVALRKLITKEA Sbjct 241 ELLTPDRVALRKLITKEA 258 >gi|13637587|sp|P46831.2|ACEA_MYCLE RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase; Short=Isocitratase Length=606 Score = 391 bits (1005), Expect = 9e-107, Method: Compositional matrix adjust. Identities = 186/204 (92%), Positives = 195/204 (96%), Gaps = 0/204 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAV ++L+FG+SEGE IGM+PEEWR F RASL+AAR KAKELG DP WDCELAKT Sbjct 365 MTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGI YAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFP+QMLAYNL Sbjct 425 PEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM+DEEM+RFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 485 SPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGP 204 ARLQRKMRLVESPYRTPQTLVGGP Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGP 568 >gi|559906|emb|CAA86357.1| isocitrate lyase [Mycobacterium leprae] Length=606 Score = 391 bits (1005), Expect = 9e-107, Method: Compositional matrix adjust. Identities = 186/204 (92%), Positives = 195/204 (96%), Gaps = 0/204 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAV ++L+FG+SEGE IGM+PEEWR F RASL+AAR KAKELG DP WDCELAKT Sbjct 365 MTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELAKT 424 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGI YAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFP+QMLAYNL Sbjct 425 PEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLAYNL 484 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWDTTGM+DEEM+RFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL Sbjct 485 SPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 544 Query 181 ARLQRKMRLVESPYRTPQTLVGGP 204 ARLQRKMRLVESPYRTPQTLVGGP Sbjct 545 ARLQRKMRLVESPYRTPQTLVGGP 568 >gi|294996827|ref|ZP_06802518.1| isocitrate lyase [Mycobacterium tuberculosis 210] Length=506 Score = 290 bits (742), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 138/138 (100%), Positives = 138/138 (100%), Gaps = 0/138 (0%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT Sbjct 369 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 428 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL Sbjct 429 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 488 Query 121 SPSFNWDTTGMTDEEMRR 138 SPSFNWDTTGMTDEEMRR Sbjct 489 SPSFNWDTTGMTDEEMRR 506 >gi|71020403|ref|XP_760432.1| hypothetical protein UM04285.1 [Ustilago maydis 521] gi|46100101|gb|EAK85334.1| hypothetical protein UM04285.1 [Ustilago maydis 521] Length=531 Score = 166 bits (420), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 97/230 (43%), Positives = 135/230 (59%), Gaps = 7/230 (3%) Query 3 YGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPE 62 YG+AVA LE + E E +R SL ++AKAK LG D +D + +T E Sbjct 306 YGDAVAAELEKKGKKAEA-----EAFRKEVVGLSLIKSKAKAKSLGVDINFDWDACRTRE 360 Query 63 GYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSP 122 GYY+ +GG AI +++A P+AD+LWMETK+ LA A++F+E + A P Q LAYNLSP Sbjct 361 GYYRYQGGTDCAINRAIAFGPYADLLWMETKSPILAQAKEFSEGVKAARPHQWLAYNLSP 420 Query 123 SFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALAR 182 SFNWD ++ E+M+ + +LGK+GFV+ FIT GG + ++ FA ++GM A Sbjct 421 SFNWDAAKLSTEQMQSYVWDLGKLGFVWQFITLGGLHSNAYISDLFAAGFAKEGMKAYVE 480 Query 183 L-QRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 L QRK R + T Q G DA L + + A+T AMGKG T+ Q Sbjct 481 LVQRKEREIGCDVLTHQKWSGANFVDACL-NTVLKAASTSAMGKGVTETQ 529 >gi|343425324|emb|CBQ68860.1| probable isocitrate lyase [Sporisorium reilianum SRZ2] Length=531 Score = 166 bits (420), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 98/230 (43%), Positives = 134/230 (59%), Gaps = 7/230 (3%) Query 3 YGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPE 62 YG+AVA LE + E E +R SL A+AKAK LG + +D + +T E Sbjct 306 YGDAVAAELEEKGKKAEA-----EAFRKEVVGQSLLKAKAKAKSLGVEVAFDWDACRTRE 360 Query 63 GYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSP 122 GYY+ +GG AI +++A P+AD+LWMETK+ LA A++FAE + A P Q LAYNLSP Sbjct 361 GYYRYQGGTDCAINRAIAFGPYADLLWMETKSPILAQAKEFAEGVKAARPHQWLAYNLSP 420 Query 123 SFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALAR 182 SFNWD ++ E+M+ + +LGK+GFV+ FIT GG ++ FA ++GM A Sbjct 421 SFNWDAAKLSTEQMKSYVWDLGKLGFVWQFITLGGLHSTAYISDLFAAGFAKEGMKAYVE 480 Query 183 L-QRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 L QRK R + T Q G DA L + + A+T AMGKG T+ Q Sbjct 481 LVQRKEREIGCDVLTHQKWSGANFVDACL-NTVLKAASTSAMGKGVTETQ 529 >gi|331218780|ref|XP_003322067.1| isocitrate lyase [Puccinia graminis f. sp. tritici CRL 75-36-700-3] gi|309301057|gb|EFP77648.1| isocitrate lyase [Puccinia graminis f. sp. tritici CRL 75-36-700-3] Length=536 Score = 165 bits (418), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 93/231 (41%), Positives = 139/231 (61%), Gaps = 6/231 (2%) Query 3 YGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKE-LGADPPWDCELAKTP 61 Y +AVA L+ G P + W + S AA+A AK+ G + WD ++ +T Sbjct 306 YSDAVAAELKV---RGAPTNKIAD-WVKSSMGLSHTAAKALAKKSYGIEIFWDWDMPRTR 361 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EG+Y+ +GG AI +++A AP++D+LWMETK+ LA A++FA+ + + +PDQ LAYNLS Sbjct 362 EGFYRYQGGTGCAINRAVAYAPYSDLLWMETKSPILAQAQEFAKGVRSVWPDQWLAYNLS 421 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLA-L 180 PSFNWD G++ E+M+ + ELGKMGF + FIT GG + ++ FA + ++GM A + Sbjct 422 PSFNWDAAGLSTEQMKSYVWELGKMGFCWQFITLGGLHSNAYISDLFAKSFAKEGMKAYV 481 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 +QRK R + T Q G +D L +G ++T AMGKG T+ Q Sbjct 482 EEIQRKEREIGCEVLTHQKWSGADYADNLLKTCTGGVSSTAAMGKGVTESQ 532 >gi|164656511|ref|XP_001729383.1| hypothetical protein MGL_3418 [Malassezia globosa CBS 7966] gi|159103274|gb|EDP42169.1| hypothetical protein MGL_3418 [Malassezia globosa CBS 7966] Length=220 Score = 163 bits (413), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 87/211 (42%), Positives = 128/211 (61%), Gaps = 5/211 (2%) Query 26 EEWRAFAARASLHAARAKAKELGADPP----WDCELAKTPEGYYQIRGGIPYAIAKSLAA 81 +E++ A++ S AAR A + G D WD + +T EG+YQ RGG A+ +++A Sbjct 7 KEFKDAASKLSNKAARDLAAKYGIDASSGFFWDWDAPRTREGFYQYRGGTQCAVNRAVAF 66 Query 82 APFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPE 141 AP+AD+LWMETK+ LA A++FA+ +HA +P+Q LAYNLSPSFNWD +++++M+ + Sbjct 67 APYADLLWMETKSPILAQAKEFADGVHAVYPNQWLAYNLSPSFNWDAAKLSEQQMKDYVW 126 Query 142 ELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARL-QRKMRLVESPYRTPQTL 200 +LGK+GFV+ FIT GG + FA ++GM A L QR+ R + T Q Sbjct 127 DLGKLGFVWQFITLGGLHSTAYITDLFAKGFAKEGMKAYVSLVQRREREIGCDVLTHQKW 186 Query 201 VGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 G D L +G ++T AMGKG T+ Q Sbjct 187 SGADFIDNLLKTVTGGVSSTAAMGKGVTETQ 217 >gi|224004182|ref|XP_002295742.1| isocitrate lyase [Thalassiosira pseudonana CCMP1335] gi|209585774|gb|ACI64459.1| isocitrate lyase [Thalassiosira pseudonana CCMP1335] Length=541 Score = 162 bits (411), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 93/237 (40%), Positives = 139/237 (59%), Gaps = 7/237 (2%) Query 1 MTYGEAVAD-VLEFGQSEGEPIGMAPEEWRAFA--ARASLHAARAKAKELGADPP--WDC 55 MT+GEAV D +L G S+ + M+ W A ++ +A R GA +D Sbjct 302 MTFGEAVLDKILSSGVSQRKKDEMS-RMWYASDPDTLSNANARRIADSIFGAKNSIYFDW 360 Query 56 ELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQM 115 E + EGYY+++ GI Y I ++ A AP+AD++WMET T + DAR+F+E + +P+QM Sbjct 361 EACRVREGYYRVKPGIEYCIQRARAYAPYADLIWMETATPGIPDARKFSEGVKKVYPNQM 420 Query 116 LAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQD 175 LAYNLSPSFNWD +GMTD+E+ RF ++LG++G+ + FIT G +G+ + A + + Sbjct 421 LAYNLSPSFNWDASGMTDDELARFNDDLGRLGYTWQFITLAGFHSNGLVVTKLARSFGDE 480 Query 176 GMLALAR-LQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 GMLA R +QR+ + E Q G D + +SG ++T AMG G T+ Q Sbjct 481 GMLAYVREIQRQEKEEEVELLKHQKWSGAELVDRMVNVASGGQSSTAAMGAGVTEDQ 537 >gi|328856720|gb|EGG05840.1| hypothetical protein MELLADRAFT_48703 [Melampsora larici-populina 98AG31] Length=537 Score = 162 bits (410), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 87/231 (38%), Positives = 138/231 (60%), Gaps = 6/231 (2%) Query 3 YGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAK-ELGADPPWDCELAKTP 61 Y +A++ ++ S I +W + S AA++ AK E G + WD ++ +T Sbjct 307 YSDAISSAMKKKGSSPSQIA----DWVKRSMGLSHEAAKSLAKKEYGVEIFWDWDMPRTR 362 Query 62 EGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLS 121 EG+Y+ +GG AI +++A AP++D+LWMETK+ L A++FA+ + + +PDQ LAYNLS Sbjct 363 EGFYRYQGGTGCAINRAVAYAPYSDLLWMETKSPILEQAKEFAKGVRSVWPDQWLAYNLS 422 Query 122 PSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLA-L 180 PSFNWD G++ ++M+ + ELGK+GF + FIT GG + ++ FA + ++GM A + Sbjct 423 PSFNWDAAGLSTQQMKDYVWELGKLGFCWQFITLGGLHSNAYISDLFAKSFAKEGMKAYV 482 Query 181 ARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 +QRK R + T Q G +D L +G ++T AMGKG T+ Q Sbjct 483 EEIQRKERDIGCDVLTHQKWSGADFADNLLKTCTGGVSSTAAMGKGVTESQ 533 >gi|320165109|gb|EFW42008.1| isocitrate lyase [Capsaspora owczarzaki ATCC 30864] Length=549 Score = 162 bits (409), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 97/225 (44%), Positives = 130/225 (58%), Gaps = 10/225 (4%) Query 8 ADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQI 67 ADVL +E + +G +E R A SL A A +K+L WD EL +T EGYY++ Sbjct 329 ADVLARWTTESKKLGH--KEARTLAE--SLLGAEA-SKQL----FWDWELPRTTEGYYRV 379 Query 68 RGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWD 127 +GG YAIA++ A +ADI+WMETKT +A AR+FAE + P Q+L YNLSPSFNWD Sbjct 380 QGGTAYAIARASAFCDYADIVWMETKTPTIAQAREFAEGVLKTHPHQLLTYNLSPSFNWD 439 Query 128 TTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALA-RLQRK 186 GM D ++ F +LG+MG+ + FIT G D + + FA + GMLA R+QR+ Sbjct 440 AAGMNDAQIESFIWDLGRMGYAWQFITLAGFHSDSLGIDMFARDFKTRGMLAYCERIQRR 499 Query 187 MRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 R + QT G D AL SG +T AMG G T++Q Sbjct 500 EREHKVETLEHQTWSGAYLVDRALTTISGGAVSTAAMGDGVTENQ 544 >gi|328766513|gb|EGF76567.1| hypothetical protein BATDEDRAFT_18060 [Batrachochytrium dendrobatidis JAM81] Length=540 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 94/232 (41%), Positives = 128/232 (56%), Gaps = 6/232 (2%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKT 60 M Y EAV VL S + ++ A AA S ARA AK LG DP +D + + Sbjct 312 MLYHEAV--VLALNASGKSSMC---ADFTAKAASLSNSDARALAKSLGVDPHFDWDAPRV 366 Query 61 PEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNL 120 EGYY+ +GG P +A+ A A +AD++WMETK A+QFAE +H P+ ML+YNL Sbjct 367 REGYYRYQGGTPACVARGSAYAKYADLIWMETKKPIYEQAKQFAEGVHKVLPEAMLSYNL 426 Query 121 SPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLAL 180 SPSFNWD GM+DE++ F +L K+GF + FIT GG + + + FA + GMLA Sbjct 427 SPSFNWDAAGMSDEKISSFIGDLAKLGFTWQFITLGGFHSNALITDVFARDYAKRGMLAY 486 Query 181 AR-LQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 + +QR+ R+ Q G D + G A+T AMGKG T+ Q Sbjct 487 VQTIQREERVNNVETLAHQKWSGAEYYDNLIKTVQGGVASTAAMGKGVTESQ 538 >gi|11131348|sp|Q9SE26.1|ACEA_DENCR RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitrase; Short=Isocitratase gi|6164959|gb|AAF04598.1|AF193815_1 isocitrate lyase [Dendrobium crumenatum] Length=574 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 89/211 (43%), Positives = 120/211 (57%), Gaps = 5/211 (2%) Query 26 EEWRA---FAARASLHAARAKAKELGA-DPPWDCELAKTPEGYYQIRGGIPYAIAKSLAA 81 EW A ++ S R A+ LGA + WD ++A+T EG+Y+ RG + A+ + A Sbjct 339 NEWAAATEYSKCVSNEQGREIAERLGAGEIFWDWDIARTREGFYRFRGSVEAAVVRGRAF 398 Query 82 APFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPE 141 AP AD++WMET + DL + +FA+ + A P+ MLAYNLSPSFNWD GMTDEEMR F Sbjct 399 APHADLIWMETSSPDLVECGKFAQGMKASHPEIMLAYNLSPSFNWDAAGMTDEEMRDFIP 458 Query 142 ELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLA-LARLQRKMRLVESPYRTPQTL 200 + KMGF + FIT GG D + + FA + GMLA + R+QR+ R Q Sbjct 459 RIAKMGFCWQFITLGGFHADALVTDTFAREFAKQGMLAYVERIQREERNNGVDTLAHQKW 518 Query 201 VGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 G D L G ++T AMGKG T+ Q Sbjct 519 SGANYYDRYLKTVQGGISSTAAMGKGVTEEQ 549 >gi|219123724|ref|XP_002182169.1| predicted protein [Phaeodactylum tricornutum CCAP 1055/1] gi|217406130|gb|EEC46070.1| predicted protein [Phaeodactylum tricornutum CCAP 1055/1] Length=593 Score = 160 bits (405), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 91/236 (39%), Positives = 133/236 (57%), Gaps = 5/236 (2%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHA-ARAKAKELGADPP---WDCE 56 MT+GEAV ++ + W A +A AR A E+ +D E Sbjct 355 MTFGEAVLATIQRSSKPAYQKRQMEQRWMASNPNTLSNAQARRMADEILGQANAVNFDWE 414 Query 57 LAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQML 116 + EGYYQ+R GI Y I +++A AP+AD++WMETK + DA QF+ +HA P QML Sbjct 415 SCRVREGYYQLRPGIEYCIQRAIAYAPYADLIWMETKIPAIDDAAQFSRGVHAVHPHQML 474 Query 117 AYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDG 176 AYNLSPSFNWD +GMTD ++ F ++LG++G+V+ FIT G +G+ + A A G Sbjct 475 AYNLSPSFNWDASGMTDSQIASFNDDLGRLGYVWQFITLAGFHGNGLVMTKLARAYGDRG 534 Query 177 MLA-LARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 M+A + ++QR+ R+ + T Q G D + +SG ++T AMG G T+ Q Sbjct 535 MIAYVEQIQRQERIHKVELLTHQKWSGAELVDQMVNVASGGVSSTAAMGAGVTEAQ 590 >gi|70607900|ref|YP_256770.1| isocitrate lyase [Sulfolobus acidocaldarius DSM 639] gi|68568548|gb|AAY81477.1| isocitrate lyase [Sulfolobus acidocaldarius DSM 639] Length=437 Score = 159 bits (403), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 87/182 (48%), Positives = 112/182 (62%), Gaps = 5/182 (2%) Query 59 KTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAY 118 +TPEGYY+++GGI Y IA+ LA AP+AD+LW ET DL +A+QFA+AIHA FP +MLAY Sbjct 253 RTPEGYYEVKGGIEYTIARGLAYAPYADLLWFETSRPDLDEAKQFADAIHAHFPGKMLAY 312 Query 119 NLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGML 178 NLSPSFNW M D ++ +F EELG MG+ F FIT G + A A + +GML Sbjct 313 NLSPSFNWKKF-MDDSKIGKFIEELGDMGYKFQFITLAGWHLINYHTFTLAKAYKNEGML 371 Query 179 ALARLQR-KMRLVESPYR--TPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQ 235 RLQ + + Y + Q VG D L +SG A+T AM KGST+ + VQ Sbjct 372 GYVRLQELEFQAQREGYTAVSHQREVGTEYFDLVLTIASGGNASTTAM-KGSTEAEQFVQ 430 Query 236 TE 237 E Sbjct 431 VE 432 >gi|342320911|gb|EGU12849.1| Isocitrate lyase [Rhodotorula glutinis ATCC 204091] Length=992 Score = 157 bits (398), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 82/207 (40%), Positives = 119/207 (58%), Gaps = 6/207 (2%) Query 34 RASLHAARAKAKEL-----GADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADIL 88 + S H + +KAK+L G DP W+ + +T EG+Y+ +GG AI +++A AP+ D+L Sbjct 367 KQSAHVSHSKAKKLASQLLGVDPYWNWDTPRTREGFYRYQGGTQCAINRAVAFAPYCDLL 426 Query 89 WMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGF 148 WMETK D A++FAE +HA +PD LAYNLSPSFNW G+ +E+M + +LGK+GF Sbjct 427 WMETKNPDYKQAKEFAEGVHAVYPDHWLAYNLSPSFNWSAAGLNEEQMASYVWDLGKLGF 486 Query 149 VFNFITYGGHQIDGVAAEEFATALRQDGMLALARL-QRKMRLVESPYRTPQTLVGGPRSD 207 + FIT G + ++ FA ++GM A + Q K R + T Q G D Sbjct 487 CWQFITLAGLHSNAYISDLFAKGFSKEGMKAYVNIVQSKEREIGCDVLTHQKWSGADYVD 546 Query 208 AALAASSGRTATTKAMGKGSTQHQHLV 234 L +G ++T AMG G T+ Q V Sbjct 547 NLLKTVTGGISSTAAMGAGVTESQFNV 573 >gi|302801596|ref|XP_002982554.1| hypothetical protein SELMODRAFT_422019 [Selaginella moellendorffii] gi|300149653|gb|EFJ16307.1| hypothetical protein SELMODRAFT_422019 [Selaginella moellendorffii] Length=566 Score = 157 bits (397), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 84/194 (44%), Positives = 113/194 (59%), Gaps = 2/194 (1%) Query 40 ARAKAKELGA-DPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLA 98 ARA A LG D W +L +T EG+Y+ +G IA+ A AP+AD+LWMET T D+ Sbjct 352 ARALAATLGVTDVFWCSDLPRTREGFYRFQGSTKACIARGCAFAPYADLLWMETATPDVV 411 Query 99 DARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGH 158 A+ FAE + A+ P+ MLAYNLSPSFNWD GM D +M+ F L +MG+ + FIT G Sbjct 412 QAQDFAEGVKAKHPEIMLAYNLSPSFNWDAAGMNDAQMQEFIPHLARMGYCWQFITLAGF 471 Query 159 QIDGVAAEEFATALRQDGMLALAR-LQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRT 217 + +AA+ FA +Q GMLA +QR+ R+ QT G D L +G Sbjct 472 HANSLAADTFARDFKQRGMLAYVEDIQRQERMNNVETLAHQTWSGANYYDQLLKTVTGGV 531 Query 218 ATTKAMGKGSTQHQ 231 ++T AM KG T+ Q Sbjct 532 SSTAAMQKGVTEDQ 545 >gi|301111828|ref|XP_002904993.1| isocitrate lyase [Phytophthora infestans T30-4] gi|262095323|gb|EEY53375.1| isocitrate lyase [Phytophthora infestans T30-4] Length=537 Score = 157 bits (397), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 94/233 (41%), Positives = 127/233 (55%), Gaps = 8/233 (3%) Query 1 MTYGEAVADVLE-FGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAK 59 MTY EAV + L+ G+S+ A +W A SL + AK LG + +D +LA+ Sbjct 310 MTYPEAVREALKKSGRSD------ALAKWNAQCLELSLPKLQVLAKSLGVNIAFDWDLAR 363 Query 60 TPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYN 119 T EGYY++RGG+ Y IA+ A +AD++WMET + AR FAE + A+ P QMLAYN Sbjct 364 TVEGYYRVRGGVEYCIARGRAYGEYADLIWMETAKPGVPLARTFAEGVKAKIPHQMLAYN 423 Query 120 LSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLA 179 LSPSFNWD GM+D E+ F +LG++GF + FIT G D + FA + GMLA Sbjct 424 LSPSFNWDAAGMSDTEIETFVTDLGRLGFCWMFITLAGFHSDSLGITRFARDYAKRGMLA 483 Query 180 LAR-LQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQ 231 +QR R Q G DA +G ++T MG G T+ Q Sbjct 484 YVEGVQRAERNEGVETLKHQGWSGTDLVDAMQNTITGGLSSTNTMGHGVTEAQ 536 >gi|302798645|ref|XP_002981082.1| hypothetical protein SELMODRAFT_420727 [Selaginella moellendorffii] gi|300151136|gb|EFJ17783.1| hypothetical protein SELMODRAFT_420727 [Selaginella moellendorffii] Length=566 Score = 157 bits (396), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 84/194 (44%), Positives = 113/194 (59%), Gaps = 2/194 (1%) Query 40 ARAKAKELGA-DPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLA 98 ARA A LG D W +L +T EG+Y+ +G IA+ A AP+AD+LWMET T D+ Sbjct 352 ARALAATLGVTDVFWCWDLPRTREGFYRFQGSTKACIARGCAFAPYADLLWMETATPDVV 411 Query 99 DARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGH 158 A+ FAE + A+ P+ MLAYNLSPSFNWD GM D +M+ F L +MG+ + FIT G Sbjct 412 QAQDFAEGVKAKHPEIMLAYNLSPSFNWDAAGMNDAQMQEFIPHLARMGYCWQFITLAGF 471 Query 159 QIDGVAAEEFATALRQDGMLALAR-LQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRT 217 + +AA+ FA +Q GMLA +QR+ R+ QT G D L +G Sbjct 472 HANSLAADTFARDFKQRGMLAYVEDIQRQERMNNVETLAHQTWSGANYYDQLLKTVTGGV 531 Query 218 ATTKAMGKGSTQHQ 231 ++T AM KG T+ Q Sbjct 532 SSTAAMQKGVTEDQ 545 >gi|164661854|ref|XP_001732049.1| hypothetical protein MGL_0642 [Malassezia globosa CBS 7966] gi|159105951|gb|EDP44835.1| hypothetical protein MGL_0642 [Malassezia globosa CBS 7966] Length=598 Score = 157 bits (396), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 93/235 (40%), Positives = 127/235 (55%), Gaps = 12/235 (5%) Query 1 MTYGEAVADVLEFGQSEGEPIGMAPEEW-RAFAARASLHAARAKAKELGAD---PPWDCE 56 +T+ EAVA+ + P + EE+ R S+ AR A+E+ D P WD + Sbjct 369 VTFNEAVAN-----HNASNPSRL--EEYDRRVDGGVSIGEARRIAQEIFGDEGVPAWDWD 421 Query 57 LAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQML 116 +T EGY+ +GGI AI + AP+A++LW+ETKT DL A+ FA IH +FP + L Sbjct 422 APRTKEGYFHFKGGISAAIKRMKQFAPYAELLWLETKTPDLVHAQGFAAKIHQDFPGKWL 481 Query 117 AYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDG 176 YNLSPSFNW G +D ++R F +L GFV I+ G V+ E + A +DG Sbjct 482 VYNLSPSFNWSAHGFSDNDLRNFISDLAHAGFVLQLISLAGIHSTAVSTYELSRAFEKDG 541 Query 177 MLALARL-QRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQH 230 MLA L QRK R + S T Q G D L S T +T +MG+GST+H Sbjct 542 MLAYVDLVQRKERELGSDMLTHQRWSGAQYMDRVLQTVSSGTCSTSSMGEGSTEH 596 >gi|62122373|dbj|BAD93181.1| isocitrate lyase [Fomitopsis palustris] Length=539 Score = 157 bits (396), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 79/190 (42%), Positives = 116/190 (62%), Gaps = 3/190 (1%) Query 45 KELG--ADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQ 102 KE G + P WD + +T EG+Y+ +GG A+ +++A AP+AD+LWMETK A A++ Sbjct 345 KEFGLRSAPFWDWDAPRTREGFYRYQGGTQCAVNRAIAFAPYADLLWMETKKPIYAQAKE 404 Query 103 FAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDG 162 FA+ +HA +PDQ LAYNLSPSFNW+ G+ +++M+ F +LGK+GF + FIT G + Sbjct 405 FADGVHAVYPDQWLAYNLSPSFNWEAAGLNEQDMKAFVWDLGKLGFCWQFITLAGLHSNA 464 Query 163 VAAEEFATALRQDGMLALARL-QRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTK 221 ++ FA A +GM A L QR+ R + T Q G D + +G ++T Sbjct 465 YISDLFAKAFATEGMKAYVELVQRREREIGCDVLTHQKWSGADYMDNLMKTVTGGVSSTA 524 Query 222 AMGKGSTQHQ 231 AMGKG T+ Q Sbjct 525 AMGKGVTESQ 534 >gi|323476618|gb|ADX81856.1| isocitrate lyase [Sulfolobus islandicus HVE10/4] Length=437 Score = 156 bits (395), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 89/189 (48%), Positives = 115/189 (61%), Gaps = 7/189 (3%) Query 59 KTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAY 118 +T EGYY+IRGGI YAIA+ LA AP+AD+LW ET DL +ARQFAEAIH +P ++LAY Sbjct 253 RTSEGYYEIRGGIEYAIARGLAYAPYADLLWFETSKPDLGEARQFAEAIHTHYPGKLLAY 312 Query 119 NLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGML 178 NLSPSFNW M D ++ RF ELG+MG+ F FIT G + + A A R +GM Sbjct 313 NLSPSFNWKKF-MDDSKISRFMNELGEMGYKFQFITLAGWHLINYHTFKLARAYRNEGMP 371 Query 179 ALARLQRKMRLVESPYRTP---QTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQ 235 A RLQ ++ T Q VG D L +SG A+T AM +GST+ + V Sbjct 372 AYVRLQESEFQAQAEGYTAVSHQREVGTDYFDLVLTIASGGEASTTAM-EGSTEAEQFV- 429 Query 236 TEVPRKLLE 244 E +K+L+ Sbjct 430 -EAKQKVLK 437 >gi|18030082|gb|AAL56614.1|AF455253_1 isocitrate lyase [Cryptococcus neoformans var. grubii] Length=549 Score = 156 bits (394), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 80/186 (44%), Positives = 113/186 (61%), Gaps = 1/186 (0%) Query 49 ADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIH 108 A P W + ++ EGYY+ +GG AI +++A AP+AD+LWMETK+ A A++FAE +H Sbjct 353 ATPYWSWDTPRSREGYYRYQGGTQCAINRAIAFAPYADLLWMETKSPIYAQAKEFAEGVH 412 Query 109 AEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEF 168 P Q LAYNLSPSFNW+ G+ +EM+ + ELGK+GFVF FIT G + + F Sbjct 413 KVHPGQWLAYNLSPSFNWEKAGLGKKEMKEYVWELGKLGFVFQFITLAGLHSNAYINDLF 472 Query 169 ATALRQDGMLALARL-QRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGS 227 A A ++GM A L Q + R + T Q G +DA L +G ++T AMGKG Sbjct 473 ANAFSKEGMKAYVELIQSREREIGCDVLTHQKWSGADYADAMLMTVTGGVSSTAAMGKGV 532 Query 228 TQHQHL 233 T++Q + Sbjct 533 TENQFV 538 Lambda K H 0.319 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 782660155392 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40