BLAST Search Results


BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1917c

Length=1459
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|167970407|ref|ZP_02552684.1|  PPE family protein [Mycobacteriu...  2651    0.0  
gi|57116928|ref|YP_177655.1|  PPE family protein [Mycobacterium t...  2651    0.0  
gi|7478714|pir||B70520  probable PPE protein - Mycobacterium tube...  2606    0.0  
gi|254232092|ref|ZP_04925419.1|  PPE family protein [Mycobacteriu...  2599    0.0  
gi|148823129|ref|YP_001287883.1|  PPE family protein [Mycobacteri...  2340    0.0  
gi|254550933|ref|ZP_05141380.1|  PPE family protein [Mycobacteriu...  2308    0.0  
gi|289762071|ref|ZP_06521449.1|  PPE family protein [Mycobacteriu...  2288    0.0  
gi|253799036|ref|YP_003032037.1|  PPE family protein [Mycobacteri...  2167    0.0  
gi|254364736|ref|ZP_04980782.1|  PPE family protein [Mycobacteriu...  2156    0.0  
gi|344219739|gb|AEN00370.1|  PPE family protein [Mycobacterium tu...  2132    0.0  
gi|297634483|ref|ZP_06952263.1|  PPE family protein [Mycobacteriu...  2130    0.0  
gi|313658804|ref|ZP_07815684.1|  PPE family protein [Mycobacteriu...  2129    0.0  
gi|297731471|ref|ZP_06960589.1|  PPE family protein [Mycobacteriu...  2083    0.0  
gi|15841389|ref|NP_336426.1|  PPE family protein [Mycobacterium t...  2064    0.0  
gi|289574600|ref|ZP_06454827.1|  PPE family protein [Mycobacteriu...  1917    0.0  
gi|323719535|gb|EGB28660.1|  PPE family protein [Mycobacterium tu...  1889    0.0  
gi|308379078|ref|ZP_07484913.2|  putative PPE family protein [Myc...  1816    0.0  
gi|308231985|ref|ZP_07414480.2|  PPE family protein [Mycobacteriu...  1813    0.0  
gi|308380227|ref|ZP_07489132.2|  putative PPE family protein [Myc...  1807    0.0  
gi|339294851|gb|AEJ46962.1|  PPE family protein [Mycobacterium tu...  1677    0.0  
gi|306789030|ref|ZP_07427352.1|  hypothetical protein TMDG_03949 ...  1605    0.0  
gi|289750499|ref|ZP_06509877.1|  PPE family protein [Mycobacteriu...  1545    0.0  
gi|289745652|ref|ZP_06505030.1|  PPE family protein [Mycobacteriu...  1541    0.0  
gi|306808203|ref|ZP_07444871.1|  hypothetical protein TMGG_00459 ...  1536    0.0  
gi|326903520|gb|EGE50453.1|  PPE family protein [Mycobacterium tu...  1527    0.0  
gi|339298476|gb|AEJ50586.1|  PPE family protein [Mycobacterium tu...  1454    0.0  
gi|121637822|ref|YP_978045.1|  PPE family protein [Mycobacterium ...  1415    0.0  
gi|289570001|ref|ZP_06450228.1|  PPE family protein [Mycobacteriu...  1399    0.0  
gi|289443397|ref|ZP_06433141.1|  PPE family protein [Mycobacteriu...  1387    0.0  
gi|298525411|ref|ZP_07012820.1|  PPE family protein [Mycobacteriu...  1377    0.0  
gi|339631970|ref|YP_004723612.1|  PPE family protein [Mycobacteri...  1353    0.0  
gi|31793109|ref|NP_855602.1|  PPE family protein [Mycobacterium b...  1310    0.0  
gi|289447533|ref|ZP_06437277.1|  PPE family protein [Mycobacteriu...  1262    0.0  
gi|308402956|ref|ZP_07493652.2|  putative PPE family protein [Myc...  1200    0.0  
gi|306797742|ref|ZP_07436044.1|  hypothetical protein TMFG_01000 ...  1151    0.0  
gi|340626927|ref|YP_004745379.1|  ppe family protein [Mycobacteri...  1150    0.0  
gi|913250|gb|AAC60492.1|  orf 5' of katG [Mycobacterium tuberculo...  1079    0.0  
gi|308373272|ref|ZP_07431668.2|  hypothetical protein TMEG_01810 ...  1031    0.0  
gi|294996832|ref|ZP_06802523.1|  PPE family protein [Mycobacteriu...  1026    0.0  
gi|308370862|ref|ZP_07422988.2|  PPE family protein [Mycobacteriu...   967    0.0  
gi|306779924|ref|ZP_07418261.1|  PPE family protein [Mycobacteriu...   944    0.0  
gi|306803629|ref|ZP_07440297.1|  hypothetical protein TMHG_01093 ...   939    0.0  
gi|306968018|ref|ZP_07480679.1|  hypothetical protein TMIG_02163 ...   900    0.0  
gi|289745649|ref|ZP_06505027.1|  predicted protein [Mycobacterium...   805    0.0  
gi|340628330|ref|YP_004746782.1|  PPE family protein [Mycobacteri...   803    0.0  
gi|289747171|ref|ZP_06506549.1|  PPE family protein [Mycobacteriu...   800    0.0  
gi|308376082|ref|ZP_07446012.2|  putative PPE family protein [Myc...   800    0.0  
gi|57117096|ref|YP_177964.1|  PPE family protein [Mycobacterium t...   800    0.0  
gi|297733008|ref|ZP_06962126.1|  PPE family protein [Mycobacteriu...   799    0.0  
gi|297636010|ref|ZP_06953790.1|  PPE family protein [Mycobacteriu...   799    0.0  


>gi|167970407|ref|ZP_02552684.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=1470

 Score = 2651 bits (6871),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1459/1459 (100%), Positives = 1459/1459 (100%), Gaps = 0/1459 (0%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  671

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
             GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  672   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  731

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  732   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  791

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  792   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  851

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  852   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  911

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  912   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  971

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  972   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1031

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1032  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1091

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1092  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1151

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP
Sbjct  1152  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1211

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
             ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1212  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1271

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT
Sbjct  1272  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1331

Query  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1380
             SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF
Sbjct  1332  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1391

Query  1381  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1440
             GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS
Sbjct  1392  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1451

Query  1441  GVNNIGQMLLGFFSPGAGP  1459
             GVNNIGQMLLGFFSPGAGP
Sbjct  1452  GVNNIGQMLLGFFSPGAGP  1470


>gi|57116928|ref|YP_177655.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661725|ref|YP_001283248.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|38490293|emb|CAE55440.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|148505877|gb|ABQ73686.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=1459

 Score = 2651 bits (6871),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1459/1459 (100%), Positives = 1459/1459 (100%), Gaps = 0/1459 (0%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV
Sbjct  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
             GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP
Sbjct  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
             ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT
Sbjct  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320

Query  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1380
             SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF
Sbjct  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1380

Query  1381  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1440
             GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS
Sbjct  1381  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1440

Query  1441  GVNNIGQMLLGFFSPGAGP  1459
             GVNNIGQMLLGFFSPGAGP
Sbjct  1441  GVNNIGQMLLGFFSPGAGP  1459


>gi|7478714|pir||B70520 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
Length=1436

 Score = 2606 bits (6754),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1436/1436 (100%), Positives = 1436/1436 (100%), Gaps = 0/1436 (0%)

Query  24    MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  83
             MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA
Sbjct  1     MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  60

Query  84    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  143
             QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM
Sbjct  61    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  120

Query  144   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  203
             WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN
Sbjct  121   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  180

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
             LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN
Sbjct  181   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
             GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  444   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  480

Query  504   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  563
             NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ
Sbjct  481   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  540

Query  564   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  623
             IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG
Sbjct  541   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  600

Query  624   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV
Sbjct  601   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV  660

Query  684   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  743
             SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN
Sbjct  661   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  720

Query  744   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  803
             SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF
Sbjct  721   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  780

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
             NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN
Sbjct  781   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  840

Query  864   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  923
             NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF
Sbjct  841   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  900

Query  924   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  983
             GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT
Sbjct  901   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  960

Query  984   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1043
             GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN
Sbjct  961   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1020

Query  1044  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1103
             GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV
Sbjct  1021  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1080

Query  1104  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1163
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140

Query  1164  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF  1223
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF
Sbjct  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF  1200

Query  1224  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1283
             NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA
Sbjct  1201  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1260

Query  1284  INPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1343
             INPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL
Sbjct  1261  INPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1320

Query  1344  GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS  1403
             GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS
Sbjct  1321  GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS  1380

Query  1404  GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1381  GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1436


>gi|254232092|ref|ZP_04925419.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|124601151|gb|EAY60161.1| PPE family protein [Mycobacterium tuberculosis C]
Length=1436

 Score = 2599 bits (6737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1432/1436 (99%), Positives = 1435/1436 (99%), Gaps = 0/1436 (0%)

Query  24    MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  83
             MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA
Sbjct  1     MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  60

Query  84    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  143
             QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM
Sbjct  61    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  120

Query  144   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  203
             WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN
Sbjct  121   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  180

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
             LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN
Sbjct  181   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
             GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  444   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  480

Query  504   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  563
             NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ
Sbjct  481   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  540

Query  564   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  623
             IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG
Sbjct  541   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  600

Query  624   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDV
Sbjct  601   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDV  660

Query  684   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  743
             SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN
Sbjct  661   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  720

Query  744   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  803
             SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF
Sbjct  721   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  780

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
             NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN
Sbjct  781   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  840

Query  864   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  923
             NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF
Sbjct  841   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  900

Query  924   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  983
             GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT
Sbjct  901   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  960

Query  984   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1043
             GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN
Sbjct  961   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1020

Query  1044  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1103
             GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV
Sbjct  1021  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1080

Query  1104  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1163
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140

Query  1164  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF  1223
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF
Sbjct  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF  1200

Query  1224  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1283
             NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA
Sbjct  1201  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1260

Query  1284  INPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1343
             INPFGLNVPLSGGT+ VTIPGFAINPFGL+VPLSGGTSPVTIPGFTIPGSPLNLTANGGL
Sbjct  1261  INPFGLNVPLSGGTNAVTIPGFAINPFGLDVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1320

Query  1344  GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS  1403
             GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS
Sbjct  1321  GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS  1380

Query  1404  GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1381  GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1436


>gi|148823129|ref|YP_001287883.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|148721656|gb|ABR06281.1| PPE family protein [Mycobacterium tuberculosis F11]
Length=1457

 Score = 2340 bits (6065),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1402/1505 (94%), Positives = 1405/1505 (94%), Gaps = 94/1505 (6%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  657

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  658   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  695

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  696   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  755

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  756   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  815

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  816   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  875

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  876   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  935

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  936   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  995

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  996   LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1055

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1056  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1115

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPI V                       PGVP
Sbjct  1116  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITV-----------------------PGVP  1152

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
             ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1153  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1212

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSP---------------------  1299
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSP                     
Sbjct  1213  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGT  1272

Query  1300  -------------------------VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSP  1334
                                      VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSP
Sbjct  1273  NAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSP  1332

Query  1335  LNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQV  1394
             LNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQV
Sbjct  1333  LNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQV  1392

Query  1395  PNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFS  1454
             PNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFS
Sbjct  1393  PNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFS  1452

Query  1455  PGAGP  1459
             PGAGP
Sbjct  1453  PGAGP  1457


>gi|254550933|ref|ZP_05141380.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
Length=1388

 Score = 2308 bits (5981),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1379/1459 (95%), Positives = 1382/1459 (95%), Gaps = 71/1459 (4%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  657

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  658   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  695

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  696   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  755

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  756   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  815

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  816   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  875

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  876   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  935

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  936   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  995

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  996   LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1055

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1056  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1115

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPI V                       PGVP
Sbjct  1116  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITV-----------------------PGVP  1152

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
             ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1153  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1212

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI                  
Sbjct  1213  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI------------------  1254

Query  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1380
                  PGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF
Sbjct  1255  -----PGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1309

Query  1381  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1440
             GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS
Sbjct  1310  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1369

Query  1441  GVNNIGQMLLGFFSPGAGP  1459
             GVNNIGQMLLGFFSPGAGP
Sbjct  1370  GVNNIGQMLLGFFSPGAGP  1388


>gi|289762071|ref|ZP_06521449.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|289709577|gb|EFD73593.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
Length=1422

 Score = 2288 bits (5928),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1372/1482 (93%), Positives = 1378/1482 (93%), Gaps = 94/1482 (6%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1126

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPI VP + I  IPL++N                                     
Sbjct  1127  ALGGVGPITVPGVPISRIPLTIN-------------------------------------  1149

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
                      IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1150  ---------IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1200

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSP---------------------  1299
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSP                     
Sbjct  1201  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGT  1260

Query  1300  --VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPG  1357
               VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPG
Sbjct  1261  NAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPG  1320

Query  1358  FGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVAN  1417
             FGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVAN
Sbjct  1321  FGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVAN  1380

Query  1418  LGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             LGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1381  LGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1422


>gi|253799036|ref|YP_003032037.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289554307|ref|ZP_06443517.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|253320539|gb|ACT25142.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289438939|gb|EFD21432.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|328458791|gb|AEB04214.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=1399

 Score = 2167 bits (5615),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1316/1459 (91%), Positives = 1339/1459 (92%), Gaps = 71/1459 (4%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1126

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
                         I IP + ++LN L    P  V  I            G +GPI     P
Sbjct  1127  ------------IRIP-VNITLNEL----PFNVAGIFT----------GYIGPI-----P  1154

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
             +S   L + +                G     I    ++ F L + L+G T    I GF+
Sbjct  1155  LSTFVLGVTL--------------AGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1200

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320
             +NPFGLN+PLSG T+ VTIPGFAINPFGL+VPLSGGT+ VTIPGFAINPFGLNVPLSGGT
Sbjct  1201  INPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGT  1260

Query  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1380
             SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF
Sbjct  1261  SPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGF  1320

Query  1381  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1440
             GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS
Sbjct  1321  GNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNS  1380

Query  1441  GVNNIGQMLLGFFSPGAGP  1459
             GVNNIGQMLLGFFSPGAGP
Sbjct  1381  GVNNIGQMLLGFFSPGAGP  1399


>gi|254364736|ref|ZP_04980782.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|134150250|gb|EBA42295.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
Length=1574

 Score = 2156 bits (5587),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1282/1326 (97%), Positives = 1289/1326 (98%), Gaps = 23/1326 (1%)

Query  24    MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  83
             MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA
Sbjct  1     MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  60

Query  84    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  143
             QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM
Sbjct  61    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  120

Query  144   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  203
             WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN
Sbjct  121   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  180

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
             LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN
Sbjct  181   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
             GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  444   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  480

Query  504   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  563
             NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ
Sbjct  481   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  540

Query  564   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  623
             IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG
Sbjct  541   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  600

Query  624   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDV
Sbjct  601   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDV  660

Query  684   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  743
             SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN
Sbjct  661   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  720

Query  744   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  803
             SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF
Sbjct  721   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  780

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
             NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN
Sbjct  781   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  840

Query  864   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  923
             NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF
Sbjct  841   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  900

Query  924   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  983
             GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT
Sbjct  901   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  960

Query  984   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1043
             GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN
Sbjct  961   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1020

Query  1044  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1103
             GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV
Sbjct  1021  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1080

Query  1104  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1163
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140

Query  1164  ALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPF  1223
             ALGGVGPI V                       PGVPISRIPLTINIRIPVNITLNELPF
Sbjct  1141  ALGGVGPITV-----------------------PGVPISRIPLTINIRIPVNITLNELPF  1177

Query  1224  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1283
             NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA
Sbjct  1178  NVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFA  1237

Query  1284  INPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1343
             IN FGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPGF I    L++  +GG 
Sbjct  1238  INRFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGT  1297

Query  1344  GPINIP  1349
               + IP
Sbjct  1298  NAVTIP  1303


 Score =  376 bits (966),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 302/644 (47%), Positives = 366/644 (57%), Gaps = 85/644 (13%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  183   LGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  241

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  242   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  301

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  302   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  361

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL                           
Sbjct  362   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL---------------------------  394

Query  1089  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGP  1147
                                TIP   L LN LG VGPI +P ITIP I L +N+ G  VGP
Sbjct  395   -------------------TIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  435

Query  1148  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--GVGPITVPGVPISRI  1204
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     VG I++P  P++  
Sbjct  436   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIG  495

Query  1205  PLTINIRI----PVNITLN----ELPFNVAG---------IFTGYIGPI-------PLST  1240
                +N  +    P +I++     E+P                +G IGPI        L  
Sbjct  496   LFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPA  555

Query  1241  FVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGG  1296
               LG+ + GG     +   G+S+    L I + G     T+   G+++    L + + GG
Sbjct  556   IPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGG  615

Query  1297  TSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITS  1354
               P T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I  
Sbjct  616   LGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAG  675

Query  1355  APGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASG  1414
              PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG
Sbjct  676   TPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSG  732

Query  1415  VANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             + N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  733   ILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  776


 Score =  153 bits (387),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 172/472 (37%), Positives = 218/472 (47%), Gaps = 94/472 (19%)

Query  417   LTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVP--------------  462
             +TIP   L LN LG VGPI +P ITIP I L +N+ G  VGPI VP              
Sbjct  1107  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTINIR  1165

Query  463   -PITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQV--------INVGSISIPAS  513
              P+ +    L  N  G   G I   P++   +G+ L+   +        +N   ++IP S
Sbjct  1166  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLS  1225

Query  514   P---------LAIGLFGVN-PTVGSIGPGSIS------IQLGTP--------EIP--AIP  547
                        AI  FG+N P  G   P +I         L  P         IP  AI 
Sbjct  1226  GATNAVTIPGFAINRFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAIN  1285

Query  548   PF--------------FPGFPPD----YVTVSGQIGPITF-------------LSGGYSL  576
             PF               PGF  +     V +SG   P+T              LSGG + 
Sbjct  1286  PFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNA  1345

Query  577   PAIP------LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  630
               IP       G+DV    G   V   G+++    L + + GG    T+   G+++    
Sbjct  1346  VTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTI--PGFAINPFG  1403

Query  631   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             L + + GG    T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPI
Sbjct  1404  LNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPI  1461

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFL  747
             NIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  
Sbjct  1462  NIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIY  1521

Query  748   NVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
             NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  1522  NVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1573


>gi|344219739|gb|AEN00370.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=1388

 Score = 2132 bits (5523),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1297/1462 (89%), Positives = 1330/1462 (91%), Gaps = 77/1462 (5%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  657

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  658   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  695

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  696   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  755

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  756   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  815

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  816   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  875

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  876   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  935

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  936   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  995

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  996   LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1055

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP-DITIPGIPLSL  1139
             VPDITIPGIPLSLNALGGVGPI VP + I  IPL++N       I +P +IT+  +P ++
Sbjct  1056  VPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNITLNELPFNV  1108

Query  1140  NAL--GGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVP  1197
               +  G +GPI +    + G+ L+    GG     +   ++    L++   G    +T+P
Sbjct  1109  AGIFTGYIGPIPLSTFVL-GVTLA----GGTLESGIQGFSVNPFGLNIPLSGATNAVTIP  1163

Query  1198  GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ  1257
             G  I+                                      F L V L+GGT    I 
Sbjct  1164  GFAINP-------------------------------------FGLDVPLSGGTNAVTIP  1186

Query  1258  GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLS  1317
             GF++NPFGL++PLSG TNAVTIPGFAINPFGL+VPLSGGT+ VTIPGFAINPFGLNVPLS
Sbjct  1187  GFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLS  1246

Query  1318  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1377
             GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA
Sbjct  1247  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1306

Query  1378  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1437
             SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA
Sbjct  1307  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1366

Query  1438  FNSGVNNIGQMLLGFFSPGAGP  1459
             FNSGVNNIGQMLLGFFSPGAGP
Sbjct  1367  FNSGVNNIGQMLLGFFSPGAGP  1388


>gi|297634483|ref|ZP_06952263.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=1388

 Score = 2130 bits (5518),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1297/1462 (89%), Positives = 1331/1462 (92%), Gaps = 77/1462 (5%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  657

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  658   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  695

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  696   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  755

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  756   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  815

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  816   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  875

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  876   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  935

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  936   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  995

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  996   LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1055

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP-DITIPGIPLSL  1139
             VPDITIPGIPLSLNALGGVGPI VP + I  IPL++N       I +P +IT+  +P ++
Sbjct  1056  VPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNITLNELPFNV  1108

Query  1140  NAL--GGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVP  1197
               +  G +GPI +    + G+ L+    GG     +   ++    L++   G    +T+P
Sbjct  1109  AGIFTGYIGPIPLSTFVL-GVTLA----GGTLESGIQGFSVNPFGLNIPLSGATNAVTIP  1163

Query  1198  GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ  1257
             G  I+  P  +N                                   V L+GGT    I 
Sbjct  1164  GFAIN--PFGLN-----------------------------------VPLSGGTSPVTIP  1186

Query  1258  GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLS  1317
             GF++NPFGL++PLSG TNAVTIPGFAINPFGL+VPLSGGT+ VTIPGFAINPFGLNVPLS
Sbjct  1187  GFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLS  1246

Query  1318  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1377
             GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA
Sbjct  1247  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1306

Query  1378  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1437
             SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA
Sbjct  1307  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1366

Query  1438  FNSGVNNIGQMLLGFFSPGAGP  1459
             FNSGVNNIGQMLLGFFSPGAGP
Sbjct  1367  FNSGVNNIGQMLLGFFSPGAGP  1388


>gi|313658804|ref|ZP_07815684.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=1399

 Score = 2129 bits (5516),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1297/1462 (89%), Positives = 1331/1462 (92%), Gaps = 77/1462 (5%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP-DITIPGIPLSL  1139
             VPDITIPGIPLSLNALGGVGPI VP + I  IPL++N       I +P +IT+  +P ++
Sbjct  1067  VPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNITLNELPFNV  1119

Query  1140  NAL--GGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVP  1197
               +  G +GPI +    + G+ L+    GG     +   ++    L++   G    +T+P
Sbjct  1120  AGIFTGYIGPIPLSTFVL-GVTLA----GGTLESGIQGFSVNPFGLNIPLSGATNAVTIP  1174

Query  1198  GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ  1257
             G  I+  P  +N                                   V L+GGT    I 
Sbjct  1175  GFAIN--PFGLN-----------------------------------VPLSGGTSPVTIP  1197

Query  1258  GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLS  1317
             GF++NPFGL++PLSG TNAVTIPGFAINPFGL+VPLSGGT+ VTIPGFAINPFGLNVPLS
Sbjct  1198  GFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLS  1257

Query  1318  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1377
             GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA
Sbjct  1258  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  1317

Query  1378  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1437
             SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA
Sbjct  1318  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  1377

Query  1438  FNSGVNNIGQMLLGFFSPGAGP  1459
             FNSGVNNIGQMLLGFFSPGAGP
Sbjct  1378  FNSGVNNIGQMLLGFFSPGAGP  1399


>gi|297731471|ref|ZP_06960589.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
Length=1365

 Score = 2083 bits (5397),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1273/1439 (89%), Positives = 1308/1439 (91%), Gaps = 77/1439 (5%)

Query  24    MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  83
             MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA
Sbjct  1     MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  60

Query  84    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  143
             QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM
Sbjct  61    QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  120

Query  144   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  203
             WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN
Sbjct  121   WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  180

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
             LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN
Sbjct  181   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
             GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  444   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  480

Query  504   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  563
             NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ
Sbjct  481   NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  540

Query  564   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  623
             IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG
Sbjct  541   IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  600

Query  624   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             YSLPAIPLGIDVGG +GP T  P   ++PAIPLGID                       V
Sbjct  601   YSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-----------------------V  635

Query  684   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  743
             SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN
Sbjct  636   SGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGN  695

Query  744   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  803
             SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF
Sbjct  696   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  755

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
             NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN
Sbjct  756   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  815

Query  864   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  923
             NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF
Sbjct  816   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  875

Query  924   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  983
             GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT
Sbjct  876   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  935

Query  984   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  1043
             GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN
Sbjct  936   GIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSN  995

Query  1044  GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIV  1103
             GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPI 
Sbjct  996   GILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIT  1055

Query  1104  VPDITIPGIPLSLNALGGVGPIVVP-DITIPGIPLSLNAL--GGVGPIVVPDITIPGIPL  1160
             VP + I  IPL++N       I +P +IT+  +P ++  +  G +GPI +    + G+ L
Sbjct  1056  VPGVPISRIPLTIN-------IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVL-GVTL  1107

Query  1161  SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNE  1220
             +    GG     +   ++    L++   G    +T+PG  I+  P  +N+          
Sbjct  1108  A----GGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAIN--PFGLNVP---------  1152

Query  1221  LPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIP  1280
                                       L+GGT    I GF++NPFGL++PLSG TNAVTIP
Sbjct  1153  --------------------------LSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIP  1186

Query  1281  GFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTAN  1340
             GFAINPFGL+VPLSGGT+ VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTAN
Sbjct  1187  GFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTAN  1246

Query  1341  GGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQG  1400
             GGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQG
Sbjct  1247  GGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQG  1306

Query  1401  GVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1307  GVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1365


>gi|15841389|ref|NP_336426.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881624|gb|AAK46240.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=1491

 Score = 2064 bits (5347),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1244/1349 (93%), Positives = 1256/1349 (94%), Gaps = 71/1349 (5%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++PAIPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPAIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1126

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPI VP + I  IPL++                                      
Sbjct  1127  ALGGVGPITVPGVPISRIPLTI--------------------------------------  1148

Query  1201  ISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1260
                     NIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS
Sbjct  1149  --------NIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFS  1200

Query  1261  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGT  1320
             VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT
Sbjct  1201  VNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGT  1260

Query  1321  SPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             + VTIPGF I    L++  +GG   + IP
Sbjct  1261  NAVTIPGFAINPFGLDVPLSGGTNAVTIP  1289


>gi|289574600|ref|ZP_06454827.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289539031|gb|EFD43609.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=1751

 Score = 1917 bits (4966),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1208/1496 (81%), Positives = 1241/1496 (83%), Gaps = 170/1496 (11%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTG--------------------  340
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTG                    
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  341   --------------------IGNTGNYNTGSFNLGSFN-----TGDFN--TGSSNTGFFN  373
                                 +GNTGN NTG FN G+++      GD+    G S T    
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  374   PGNLN-TGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGF--------------SGTL-  417
                L+  G+G+ G +            G    G   G I                SG L 
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  491

Query  418   --------TIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPA  468
                     T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPA
Sbjct  492   GPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPA  551

Query  469   IGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS  528
             IGLG++S+GALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS
Sbjct  552   IGLGVSSSGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS  611

Query  529   IGP---------------------------------GSISIQLGTPEIPAIP--------  547
             IGP                                 G I+   G   +PAIP        
Sbjct  612   IGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGG  671

Query  548   --PF------------------------FPGFPPDY--------VTVSGQIGPITFLSGG  573
               PF                        F  FP  Y        + V G +GP T    G
Sbjct  672   LGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  731

Query  574   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGI  633
             YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAI LGI
Sbjct  732   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIQLGI  791

Query  634   DVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIP  693
             DVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIP
Sbjct  792   DVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIP  851

Query  694   IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLT  753
             IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLT
Sbjct  852   IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLT  911

Query  754   SGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTL  813
             SGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTL
Sbjct  912   SGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTL  971

Query  814   NLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPG  873
             NLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPG
Sbjct  972   NLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPG  1031

Query  874   LTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNI  933
             LTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNI
Sbjct  1032  LTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNI  1091

Query  934   GFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNT  993
             GFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNT
Sbjct  1092  GFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNT  1151

Query  994   GSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQG  1053
             GSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQG
Sbjct  1152  GSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQG  1211

Query  1054  LIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIP  1113
             LIGYSDTLSIP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIP
Sbjct  1212  LIGYSDTLSIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIP  1271

Query  1114  LSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVV  1173
             LSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI V
Sbjct  1272  LSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITV  1331

Query  1174  PDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYI  1233
                                    PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYI
Sbjct  1332  -----------------------PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYI  1368

Query  1234  GPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPL  1293
             GPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPL
Sbjct  1369  GPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPL  1428

Query  1294  SGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             SGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPGF I    L++  +GG   + IP
Sbjct  1429  SGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIP  1484


 Score =  246 bits (629),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 284/757 (38%), Positives = 363/757 (48%), Gaps = 127/757 (16%)

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFGN G+ N GFG  G N
Sbjct  226   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDN  285

Query  864   NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG-NIGIGLTGDNQVG  922
               GF     G      NIG  N G  N G  N G GN G GN+GT  N GIG TG    G
Sbjct  286   QQGFG----GWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTG  341

Query  923   F------------------GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTG  964
             F                  G+ N GS N G FN+G+ N GFFN GN N G+GN+GN NTG
Sbjct  342   FFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTG  401

Query  965   LGNVGNANTGLFNTGNVN------------------TGIGNAGSYNTGSYNAGDTNTGDL  1006
               N GN + G F  G+                     G+G+ G     S    +   G +
Sbjct  402   GFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLG-I  460

Query  1007  NPGNANTGYLNLGDLNTGWGNIGDLNTGALISG---------SYSNGILWRGDYQGLIGY  1057
             N   A  G +N+  +      +G  ++GAL+           +   G+   G   G I  
Sbjct  461   NSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINV  520

Query  1058  SDTLSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLS  1115
                +++PAI L V  +G  +GPI VP IT+P I L +++ G  VGPI +P IT+  I L 
Sbjct  521   PP-ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINIPPITLNSIGLE  579

Query  1116  LNALGGVGPIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI---------  1153
             L+A      I V  I+IP  PL++  L GV P V              P+I         
Sbjct  580   LSAFQ---VINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPG  635

Query  1154  ----------------------TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALG  1189
                                   ++P IPL ++  GG+GP  V PD  ++P IPL ++  G
Sbjct  636   FPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG  695

Query  1190  GVGPITV--PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTL  1247
             G+GP TV   G  +  IPL I++                G FT +     L    LG+ +
Sbjct  696   GLGPFTVFPDGYSLPAIPLGIDVG------------GGLGPFTVFPDGYSLPAIPLGIDV  743

Query  1248  AGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI-  1302
              GG     +   G+S+    L I + G     T+   G+++    L + + GG  P T+ 
Sbjct  744   GGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIQLGIDVGGGLGPFTVF  803

Query  1303  -PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNS  1361
               G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNS
Sbjct  804   PDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNS  863

Query  1362  TTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNT  1421
             TTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNT
Sbjct  864   TTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNT  920

Query  1422  VSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             VSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  921   VSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  957


 Score =  135 bits (341),  Expect = 5e-29, Method: Compositional matrix adjust.
 Identities = 141/380 (38%), Positives = 196/380 (52%), Gaps = 32/380 (8%)

Query  423   GLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGP  482
             GL++   G+   +TIP   I   GL +  SG    P+ +P   +   GL +  +G     
Sbjct  1400  GLNIPLSGATNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLDVPLSGG-TNA  1457

Query  483   INIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPE  542
             + IP   +N  GL++      N  +++IP    AI  FG++  + S G  +++I    P 
Sbjct  1458  VTIPGFAINPFGLDVPLSGGTN--AVTIPG--FAINPFGLDVPL-SGGTNAVTI----PG  1508

Query  543   IPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLP  602
               AI PF    P     +SG   P+T    G+++    L + + GG  P T+   G+++ 
Sbjct  1509  F-AINPFGLDVP-----LSGGTSPVTIP--GFAINPFGLDVPLSGGTSPVTI--PGFAIN  1558

Query  603   AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG  662
                L + + GG    T+   G+++    L + + GG  P T+   G+++    L + + G
Sbjct  1559  PFGLNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSG  1614

Query  663   AIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTS  722
                P+T P  TIP  PL +  +G LGPINI       PGFGNSTTTPSSGFFNSG G  S
Sbjct  1615  GTSPVTIPGFTIPGSPLNLTANGGLGPINI----TSAPGFGNSTTTPSSGFFNSGDGSAS  1670

Query  723   GFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAF  779
             GFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF
Sbjct  1671  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1730

Query  780   HSGVGNTDSQLAGFMRNAAG  799
             +SGV N    L GF    AG
Sbjct  1731  NSGVNNIGQMLLGFFSPGAG  1750


>gi|323719535|gb|EGB28660.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=1157

 Score = 1889 bits (4893),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1139/1217 (94%), Positives = 1142/1217 (94%), Gaps = 71/1217 (5%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG                         YS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG-------------------------YS  586

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV
Sbjct  587   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  646

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
             GGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  647   GGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI                 
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI-----------------  1049

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
                                          P IPLS+   GG+GPIVVPDITIPGIPLSLN
Sbjct  1050  -----------------------------PAIPLSVEVNGGIGPIVVPDITIPGIPLSLN  1080

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP
Sbjct  1081  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1140

Query  1201  ISRIPLTINIRIPVNIT  1217
             ISRIPLTINIRIPVNIT
Sbjct  1141  ISRIPLTINIRIPVNIT  1157


 Score =  375 bits (964),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 300/635 (48%), Positives = 362/635 (58%), Gaps = 92/635 (14%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL                           
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL---------------------------  428

Query  1089  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGP  1147
                                TIP   L LN LG VGPI +P ITIP I L +N+ G  VGP
Sbjct  429   -------------------TIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  469

Query  1148  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--GVGPITVPGVPISRI  1204
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     VG I++P  P++  
Sbjct  470   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIG  529

Query  1205  PLTINIRI----PVNITLN----ELPFNVAG---------IFTGYIGPIPLSTFVLGVTL  1247
                +N  +    P +I++     E+P                +G IGPI   TF+ G   
Sbjct  530   LFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPI---TFLSG---  583

Query  1248  AGGTLESGIQGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--P  1303
                       G+S+    L I + G     T+   G+++    L + + GG  P T+   
Sbjct  584   ----------GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  633

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  634   GYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  693

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVS
Sbjct  694   TPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVS  750

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  751   GLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  785


 Score = 71.6 bits (174),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 61/166 (37%), Positives = 77/166 (47%), Gaps = 62/166 (37%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRI  1212
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N   
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNAL-  1105

Query  1213  PVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSG  1272
                               G +GPI +                                  
Sbjct  1106  ------------------GGVGPIVVPD--------------------------------  1115

Query  1273  ATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAIN--PFGLNVPL  1316
                 +TIPG    P  LN    GG  P+T+PG  I+  P  +N+ +
Sbjct  1116  ----ITIPGI---PLSLNA--LGGVGPITVPGVPISRIPLTINIRI  1152


 Score = 47.8 bits (112),  Expect = 0.014, Method: Compositional matrix adjust.
 Identities = 29/84 (35%), Positives = 46/84 (55%), Gaps = 0/84 (0%)

Query  1266  LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTI  1325
             L++ ++G    + +P   I    L++   GG  P+ +P   I    L++   GG  P+ +
Sbjct  1054  LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVV  1113

Query  1326  PGFTIPGSPLNLTANGGLGPINIP  1349
             P  TIPG PL+L A GG+GPI +P
Sbjct  1114  PDITIPGIPLSLNALGGVGPITVP  1137


 Score = 43.1 bits (100),  Expect = 0.35, Method: Compositional matrix adjust.
 Identities = 50/178 (29%), Positives = 68/178 (39%), Gaps = 67/178 (37%)

Query  1176  ITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGP  1235
             ++IP IPLS+   GG+GPI VP + I  IPL++N                     G +GP
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNAL-------------------GGVGP  1087

Query  1236  IPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSG  1295
             I +                                      +TIPG    P  LN    G
Sbjct  1088  IVVPD------------------------------------ITIPGI---PLSLNA--LG  1106

Query  1296  GTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINIT  1353
             G  P+ +P   I    L++   GG  P+T+PG  I   PL +        I IP+NIT
Sbjct  1107  GVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNIT  1157


>gi|308379078|ref|ZP_07484913.2| putative PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308358264|gb|EFP47115.1| putative PPE family protein [Mycobacterium tuberculosis SUMu010]
Length=1108

 Score = 1816 bits (4705),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1088/1122 (97%), Positives = 1092/1122 (98%), Gaps = 25/1122 (2%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++P+IPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPSIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1122
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1108


 Score =  377 bits (968),  Expect = 9e-102, Method: Compositional matrix adjust.
 Identities = 300/635 (48%), Positives = 362/635 (58%), Gaps = 92/635 (14%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL                           
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL---------------------------  428

Query  1089  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGP  1147
                                TIP   L LN LG VGPI +P ITIP I L +N+ G  VGP
Sbjct  429   -------------------TIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  469

Query  1148  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--GVGPITVPGVPISRI  1204
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     VG I++P  P++  
Sbjct  470   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIG  529

Query  1205  PLTINIRI----PVNITLN----ELPFNVAG---------IFTGYIGPIPLSTFVLGVTL  1247
                +N  +    P +I++     E+P                +G IGPI   TF+ G   
Sbjct  530   LFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPI---TFLSG---  583

Query  1248  AGGTLESGIQGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--P  1303
                       G+S+    L I + G     T+   G+++    L + + GG  P T+   
Sbjct  584   ----------GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  633

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  634   GYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  693

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVS
Sbjct  694   TPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVS  750

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  751   GLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  785


 Score = 80.1 bits (196),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1103


 Score = 40.0 bits (92),  Expect = 3.3, Method: Compositional matrix adjust.
 Identities = 20/38 (53%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+V ++GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  1054  LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVP  1091


 Score = 38.9 bits (89),  Expect = 6.7, Method: Compositional matrix adjust.
 Identities = 26/74 (36%), Positives = 41/74 (56%), Gaps = 5/74 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  1040  LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1094

Query  1330  IPGSPLNLTANGGL  1343
             IPG PL+L A GG+
Sbjct  1095  IPGIPLSLNALGGV  1108


>gi|308231985|ref|ZP_07414480.2| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308215384|gb|EFO74783.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
Length=1106

 Score = 1813 bits (4697),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1086/1120 (97%), Positives = 1090/1120 (98%), Gaps = 25/1120 (2%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++P+IPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPSIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1106


 Score =  377 bits (968),  Expect = 9e-102, Method: Compositional matrix adjust.
 Identities = 300/635 (48%), Positives = 362/635 (58%), Gaps = 92/635 (14%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL                           
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL---------------------------  428

Query  1089  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGP  1147
                                TIP   L LN LG VGPI +P ITIP I L +N+ G  VGP
Sbjct  429   -------------------TIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  469

Query  1148  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--GVGPITVPGVPISRI  1204
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     VG I++P  P++  
Sbjct  470   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIG  529

Query  1205  PLTINIRI----PVNITLN----ELPFNVAG---------IFTGYIGPIPLSTFVLGVTL  1247
                +N  +    P +I++     E+P                +G IGPI   TF+ G   
Sbjct  530   LFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPI---TFLSG---  583

Query  1248  AGGTLESGIQGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--P  1303
                       G+S+    L I + G     T+   G+++    L + + GG  P T+   
Sbjct  584   ----------GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  633

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  634   GYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  693

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVS
Sbjct  694   TPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVS  750

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  751   GLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  785


 Score = 80.1 bits (196),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1103


 Score = 40.0 bits (92),  Expect = 3.3, Method: Compositional matrix adjust.
 Identities = 20/38 (53%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+V ++GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  1054  LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVP  1091


>gi|308380227|ref|ZP_07489132.2| putative PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308362191|gb|EFP51042.1| putative PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=1102

 Score = 1807 bits (4681),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1082/1116 (97%), Positives = 1086/1116 (98%), Gaps = 25/1116 (2%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
             VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
             QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192   QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
             VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252   VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
             GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312   GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
             DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372   DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
             AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432   AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
             GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492   GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
             PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552   PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG +GP T  P   ++P+IPLGID 
Sbjct  612   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPSIPLGID-  668

Query  661   GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
                                   VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  669   ----------------------VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  706

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  707   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  766

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  767   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  826

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  827   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  886

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  887   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  946

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  947   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1006

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1007  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1066

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSL  1116
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSL
Sbjct  1067  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSL  1102


 Score =  377 bits (968),  Expect = 9e-102, Method: Compositional matrix adjust.
 Identities = 300/635 (48%), Positives = 362/635 (58%), Gaps = 92/635 (14%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL                           
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL---------------------------  428

Query  1089  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGP  1147
                                TIP   L LN LG VGPI +P ITIP I L +N+ G  VGP
Sbjct  429   -------------------TIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  469

Query  1148  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--GVGPITVPGVPISRI  1204
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     VG I++P  P++  
Sbjct  470   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIG  529

Query  1205  PLTINIRI----PVNITLN----ELPFNVAG---------IFTGYIGPIPLSTFVLGVTL  1247
                +N  +    P +I++     E+P                +G IGPI   TF+ G   
Sbjct  530   LFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPI---TFLSG---  583

Query  1248  AGGTLESGIQGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--P  1303
                       G+S+    L I + G     T+   G+++    L + + GG  P T+   
Sbjct  584   ----------GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  633

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  634   GYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  693

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVS
Sbjct  694   TPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVS  750

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  751   GLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  785


 Score = 78.6 bits (192),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 40/56 (72%), Positives = 47/56 (84%), Gaps = 0/56 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTI  1208
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSL  1102


 Score = 40.0 bits (92),  Expect = 3.3, Method: Compositional matrix adjust.
 Identities = 20/38 (53%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+V ++GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  1054  LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVP  1091


 Score = 38.9 bits (89),  Expect = 7.6, Method: Compositional matrix adjust.
 Identities = 18/34 (53%), Positives = 25/34 (74%), Gaps = 0/34 (0%)

Query  1176  ITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPI VP + I  IPL++N
Sbjct  1047  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLN  1080


>gi|339294851|gb|AEJ46962.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
Length=1248

 Score = 1677 bits (4342),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1004/1161 (87%), Positives = 1023/1161 (89%), Gaps = 118/1161 (10%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  88    ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  147

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  148   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  207

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  208   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  267

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  268   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  327

Query  656   LGIDVGG-------------------------AIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             LGIDVGG                         AIGPLTTPPITIP+IPLGIDVSGSLGPI
Sbjct  328   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPI  387

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  750
             NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG
Sbjct  388   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  447

Query  751   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  810
             PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND
Sbjct  448   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  507

Query  811   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  870
             GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT
Sbjct  508   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  567

Query  871   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  930
             GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS
Sbjct  568   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  627

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS
Sbjct  628   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  687

Query  991   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1050
             YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD
Sbjct  688   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  747

Query  1051  YQGLIGYSDTLSIPAIPLSVEVNGGI-----------------------GPIVVPDITIP  1087
             YQGLIGYSDTLSIPAIPLSVEVNGGI                       GPIVVPDITIP
Sbjct  748   YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  807

Query  1088  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1147
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP
Sbjct  808   GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  867

Query  1148  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  1207
             IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT
Sbjct  868   IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  927

Query  1208  INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1267
             INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN
Sbjct  928   INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  987

Query  1268  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPG  1327
             IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPG
Sbjct  988   IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPG  1047

Query  1328  F------------------TIPGSP----------------------------LNLTANG  1341
             F                  TIPG                              LN+  +G
Sbjct  1048  FAINPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSG  1107

Query  1342  GLGPINI--------PINITSAPGFG------NSTTTP---------SSGFFNSGDGSAS  1378
             G  P+ I        P+N+T+  G G      N T+ P         SSGFFNSGDGSAS
Sbjct  1108  GTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSAS  1167

Query  1379  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1438
             GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF
Sbjct  1168  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1227

Query  1439  NSGVNNIGQMLLGFFSPGAGP  1459
             NSGVNNIGQMLLGFFSPGAGP
Sbjct  1228  NSGVNNIGQMLLGFFSPGAGP  1248


 Score =  304 bits (779),  Expect = 7e-80, Method: Compositional matrix adjust.
 Identities = 220/435 (51%), Positives = 268/435 (62%), Gaps = 56/435 (12%)

Query  206  LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  264
            +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  547  IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  606

Query  265  NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  324
            NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  607  NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  665

Query  325  GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  384
            G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  666  GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  725

Query  385  GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  444
            G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP 
Sbjct  726  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  785

Query  445  IGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---Q  501
            I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     
Sbjct  786  IPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVG  843

Query  502  VINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTV  560
             I V  I+IP  PL++  L GV P V              P+I                 
Sbjct  844  PIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI-----------------  873

Query  561  SGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVF  620
                          ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP TV 
Sbjct  874  --------------TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPITV-  916

Query  621  PDGYSLPAIPLGIDV  635
              G  +  IPL I++
Sbjct  917  -PGVPISRIPLTINI  930


 Score =  146 bits (368),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 181/493 (37%), Positives = 238/493 (49%), Gaps = 114/493 (23%)

Query  1076  IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIP  1133
             +GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P
Sbjct  8     VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  67

Query  1134  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1190
              I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  68    AIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  127

Query  1191  VGPITVPGVPISRIPLTIN--------IRIPVNITLNELPFNVAGIFTGYIGPI-----P  1237
             VGPI VP + +  I L IN        I IP  ITLN +   ++      +G I     P
Sbjct  128   VGPINVPPITVPAIGLGINSTGALVGPINIP-PITLNSIGLELSAFQVINVGSISIPASP  186

Query  1238  LSTFVLGVTLAGGTLESG---IQ-----------------------------------GF  1259
             L+  + GV    G++  G   IQ                                   G+
Sbjct  187   LAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGY  246

Query  1260  SVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVP  1315
             S+    L I + G     T+   G+++    L + + GG  P T+   G+++    L + 
Sbjct  247   SLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGID  306

Query  1316  LSGGTSPVTI--PGFTIPGSPLNLTANGGLGPINI-------------------------  1348
             + GG  P T+   G+++P  PL +   GGLGP  +                         
Sbjct  307   VGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTT  366

Query  1349  -PINITSAP----------------------GFGNSTTTPSSGFFNSGDGSASGFGNVGP  1385
              PI I + P                      GFGNSTTTPSSGFFNSG G  SGFGNVG 
Sbjct  367   PPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGS  426

Query  1386  GISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNI  1445
             G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N 
Sbjct  427   GGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNT  483

Query  1446  GQMLLGFFSPGAG  1458
                L GF    AG
Sbjct  484   DSQLAGFMRNAAG  496


 Score =  117 bits (292),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 121/293 (42%), Positives = 153/293 (53%), Gaps = 51/293 (17%)

Query  449  INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQV----IN  504
            ++SSGALVGPINVPPITVPAIGLG++S+GALVGPIN+PPIT+ +IGL +S+       IN
Sbjct  1    MSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPIN  60

Query  505  VGSISIPASPLA-------IGLFGVNP-TVGSIGPGSISIQLGTPEIPAIPPFFPGFPPD  556
            V  I++PA  L        +G   V P TV +IG G  S       I   P   P     
Sbjct  61   VPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLG  120

Query  557  YVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFP------------------D  597
              +    +GPI       ++PAI LGI+  G L GP  + P                   
Sbjct  121  VSSSGALVGPINVPP--ITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVG  178

Query  598  GYSLPAIPLGIDVGG--------GLGPFTVFPDGYSLPAIPLG--------IDVGGGLGP  641
              S+PA PL I + G        G G  ++      +PAIP          + V G +GP
Sbjct  179  SISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGP  238

Query  642  FTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPSIPLGIDVSGSLGPINI  692
             T    GYSLPAIPLGIDVGG +GP T  P   ++P+IPLGIDV G LGP  +
Sbjct  239  ITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  291


 Score = 50.8 bits (120),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 56/150 (38%), Positives = 73/150 (49%), Gaps = 18/150 (12%)

Query  260  NTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNT  319
            N G+G  GF     N    G  N G    G+ N G    G+ NT T    +G + +++++
Sbjct  423  NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLATSAFHS  478

Query  320  GIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-  369
            G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N GS N  
Sbjct  479  GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  538

Query  370  ----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
                GF N G+ N G GN G+ N G  N+G
Sbjct  539  NGSFGFGNIGSNNFGFGNVGSNNLGFANTG  568


 Score = 44.3 bits (103),  Expect = 0.20, Method: Compositional matrix adjust.
 Identities = 63/186 (34%), Positives = 87/186 (47%), Gaps = 42/186 (22%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  468
             SG  ++PA  L ++  G +GP T+     ++P I LGI+  G L GP  V P   ++PA
Sbjct  242  LSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPA  300

Query  469  IGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS  528
            I LGI+  G L GP  + P                     S+PA PL I + G       
Sbjct  301  IPLGIDVGGGL-GPFTVFP------------------DGYSLPAIPLGIDVGG-------  334

Query  529  IGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGG  588
             G G  ++      +PAI        P  + V G IGP+T  +   ++PAIPLGIDV G 
Sbjct  335  -GLGPFTVFPDGYSLPAI--------PLGIDVGGAIGPLT--TPPITIPAIPLGIDVSGS  383

Query  589  LGPFTV  594
            LGP  +
Sbjct  384  LGPINI  389


>gi|306789030|ref|ZP_07427352.1| hypothetical protein TMDG_03949 [Mycobacterium tuberculosis SUMu004]
 gi|308334436|gb|EFP23287.1| hypothetical protein TMDG_03949 [Mycobacterium tuberculosis SUMu004]
Length=1020

 Score = 1605 bits (4157),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 953/1066 (90%), Positives = 976/1066 (92%), Gaps = 46/1066 (4%)

Query  248   LGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  307
             +GNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN
Sbjct  1     MGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  60

Query  308   FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  367
             FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS
Sbjct  61    FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  120

Query  368   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN  427
             NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN
Sbjct  121   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN  180

Query  428   GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  487
             GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP
Sbjct  181   GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  240

Query  488   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  547
             ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP
Sbjct  241   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  300

Query  548   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  607
             PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG
Sbjct  301   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  360

Query  608   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL  667
             IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL
Sbjct  361   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL  420

Query  668   TTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV  727
             TTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV
Sbjct  421   TTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV  480

Query  728   GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD  787
             GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD
Sbjct  481   GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD  540

Query  788   SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF  847
             SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF
Sbjct  541   SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF  600

Query  848   GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG  907
             GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG
Sbjct  601   GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG  660

Query  908   TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN  967
             TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN
Sbjct  661   TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN  720

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
             VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN
Sbjct  721   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  780

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
             IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP
Sbjct  781   IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  840

Query  1088  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1147
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N       
Sbjct  841   GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------  893

Query  1148  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  1207
                  I IP + ++LN L    P  V  I            G +GPI     P+S   L 
Sbjct  894   -----IRIP-VNITLNEL----PFNVAGI----------FTGYIGPI-----PLSTFVLG  928

Query  1208  INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1267
             + +                G     I    ++ F L + L+G T    I GF++NPFGLN
Sbjct  929   VTLA--------------GGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLN  974

Query  1268  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLN  1313
             +PLSG T+ VTIPGFAINPFGL+VPLSGGT+ VTIPGFAINPFGL+
Sbjct  975   VPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLD  1020


 Score =  350 bits (897),  Expect = 2e-93, Method: Compositional matrix adjust.
 Identities = 282/601 (47%), Positives = 341/601 (57%), Gaps = 84/601 (13%)

Query  893   FANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGN  952
               N GNGNIGFGNTG GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN
Sbjct  1     MGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  60

Query  953   VGIGNSG-NYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNA  1011
              GIGNSG +YNTG+GN G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++
Sbjct  61    FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  120

Query  1012  NTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVE  1071
             NTG+ N G+LNTG GN G++NTG   SG+YSNG  WRGDYQGLIG+S TL          
Sbjct  121   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL----------  170

Query  1072  VNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1131
                                                 TIP   L LN LG VGPI +P IT
Sbjct  171   ------------------------------------TIPAAGLDLNGLGSVGPITIPSIT  194

Query  1132  IPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG  1189
             IP I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A  
Sbjct  195   IPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQ  254

Query  1190  --GVGPITVPGVPISRIPLTINIRI----PVNITLN----ELPFNVAG---------IFT  1230
                VG I++P  P++     +N  +    P +I++     E+P                +
Sbjct  255   VINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVS  314

Query  1231  GYIGPI-------PLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--  1279
             G IGPI        L    LG+ + GG     +   G+S+    L I + G     T+  
Sbjct  315   GQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFP  374

Query  1280  PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNL  1337
              G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL +
Sbjct  375   DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGI  434

Query  1338  TANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNA  1397
               +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N 
Sbjct  435   DVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL  494

Query  1398  LQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGA  1457
                G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    A
Sbjct  495   ---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAA  551

Query  1458  G  1458
             G
Sbjct  552   G  552


 Score =  275 bits (704),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 178/308 (58%), Positives = 216/308 (71%), Gaps = 4/308 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  602  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  661

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  662  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  720

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  721  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  780

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  781  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  840

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P + ++ I L ++    +
Sbjct  841  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTINIRIPV  898

Query  504  NVGSISIP  511
            N+    +P
Sbjct  899  NITLNELP  906


 Score = 40.4 bits (93),  Expect = 2.9, Method: Compositional matrix adjust.
 Identities = 35/74 (48%), Positives = 42/74 (57%), Gaps = 5/74 (6%)

Query  207  GLANSGFGQMGAANLGILNLGSLNPG-----GNNFGLGNVGSNNVGLGNTGNGNIGFGNT  261
            G+AN+G G  G  N G  NLGS N G      +N G  N G+ N G+GNTGN N G  N+
Sbjct  88   GIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNS  147

Query  262  GNGNIGFGLTGDNQ  275
            GN + GF   GD Q
Sbjct  148  GNYSNGFFWRGDYQ  161


 Score = 38.5 bits (88),  Expect = 10.0, Method: Compositional matrix adjust.
 Identities = 45/99 (46%), Positives = 53/99 (54%), Gaps = 7/99 (7%)

Query  207  GLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNI  266
            G AN+GF   G AN GI N G+ N G  N     +GS N G  NTG+ N GF N GN N 
Sbjct  78   GQANTGFFNAGIANTGIGNTGNYNTGSFN-----LGSFNTGDFNTGSSNTGFFNPGNLNT  132

Query  267  GFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGT  305
            G G TG+     GG+NSG  + G F  G     IG +GT
Sbjct  133  GVGNTGNVNT--GGFNSGNYSNGFFWRGDYQGLIGFSGT  169


>gi|289750499|ref|ZP_06509877.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289691086|gb|EFD58515.1| PPE family protein [Mycobacterium tuberculosis T92]
Length=1660

 Score = 1545 bits (4001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 934/1138 (83%), Positives = 968/1138 (86%), Gaps = 95/1138 (8%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  523   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  582

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  583   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  642

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  643   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  702

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  703   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  762

Query  656   LGIDVGG-------------------------AIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             LGIDVGG                         AIGPLTTPPITIP+IPLGIDVSG LGPI
Sbjct  763   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGRLGPI  822

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  750
             NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG
Sbjct  823   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  882

Query  751   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  810
             PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND
Sbjct  883   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  942

Query  811   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  870
             GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT
Sbjct  943   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  1002

Query  871   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  930
             GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS
Sbjct  1003  GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  1062

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS
Sbjct  1063  GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  1122

Query  991   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1050
             YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD
Sbjct  1123  YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1182

Query  1051  YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1110
             YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP
Sbjct  1183  YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1242

Query  1111  GIPLSLNALGGVGPIVVPDITIPGIPLSLNAL-------------------GGVGPIVVP  1151
             GIPLSLNALGGVGPI VP + I  IPL++N                     G +GPI + 
Sbjct  1243  GIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLS  1302

Query  1152  D------------------------------------ITIPGI---PLSLNA--LGGVGP  1170
                                                  +TIPG    P  LN    GG  P
Sbjct  1303  TFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSP  1362

Query  1171  IVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVN-ITLNELPFNVAGI-  1228
             + +P   I    L +   GG   +T+PG  I+   L + +    N +T+     N  G+ 
Sbjct  1363  VTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLD  1422

Query  1229  --FTGYIGPIPLSTFV-----LGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPG  1281
                +G   P+ +  F      L V L+GGT    I GF++NPFGLN+PLSG TNAVTIPG
Sbjct  1423  VPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLNVPLSGGTNAVTIPG  1482

Query  1282  FAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANG  1341
             FAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANG
Sbjct  1483  FAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANG  1542

Query  1342  GLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGG  1401
             GLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGG
Sbjct  1543  GLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGG  1602

Query  1402  VSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             VSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1603  VSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1660


>gi|289745652|ref|ZP_06505030.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289686180|gb|EFD53668.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=1318

 Score = 1541 bits (3989),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 899/959 (94%), Positives = 914/959 (96%), Gaps = 26/959 (2%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  112   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  171

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  172   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  231

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  232   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  291

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  292   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  351

Query  656   LGIDVGG-------------------------AIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             LGIDVGG                         AIGPLTTPPITIP+IPLGIDVSGSLGPI
Sbjct  352   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPI  411

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  750
             NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG
Sbjct  412   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  471

Query  751   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  810
             PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND
Sbjct  472   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  531

Query  811   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  870
             GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT
Sbjct  532   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  591

Query  871   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  930
             GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS
Sbjct  592   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  651

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS
Sbjct  652   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  711

Query  991   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1050
             YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD
Sbjct  712   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  771

Query  1051  YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1110
             YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP
Sbjct  772   YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  831

Query  1111  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1170
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP
Sbjct  832   GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  891

Query  1171  IVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFT  1230
             IVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFT
Sbjct  892   IVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFT  951

Query  1231  GYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLN  1290
             GYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLN
Sbjct  952   GYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLN  1011

Query  1291  VPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             VPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPGF I    LN+  +GG   + IP
Sbjct  1012  VPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIP  1070


 Score =  293 bits (751),  Expect = 1e-76, Method: Compositional matrix adjust.
 Identities = 231/492 (47%), Positives = 287/492 (59%), Gaps = 42/492 (8%)

Query  206   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  264
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  571   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  630

Query  265   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  324
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  631   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  689

Query  325   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  384
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  690   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  749

Query  385   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  444
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP 
Sbjct  750   GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  809

Query  445   IGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---Q  501
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     
Sbjct  810   IPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVG  867

Query  502   VINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVS  561
              I V  I+IP  PL++        +G +GP    I +    IP I        P  +   
Sbjct  868   PIVVPDITIPGIPLSLN------ALGGVGP----IVVPDITIPGI--------PLSLNAL  909

Query  562   GQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFP  621
             G +GPIT    G  +  IPL I++          P   +L  +P  +      G FT + 
Sbjct  910   GGVGPITVP--GVPISRIPLTINI--------RIPVNITLNELPFNVA-----GIFTGYI  954

Query  622   DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGI  681
                 L    LG+ + GG     +   G+S+    L I + GA   +T P   I    L +
Sbjct  955   GPIPLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNV  1012

Query  682   DVSGSLGPINIP  693
              +SG   P+ IP
Sbjct  1013  PLSGGTSPVTIP  1024


 Score =  176 bits (446),  Expect = 3e-41, Method: Compositional matrix adjust.
 Identities = 185/460 (41%), Positives = 246/460 (54%), Gaps = 65/460 (14%)

Query  1061  LSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNA  1118
             +++PAI L V  +G  +GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++
Sbjct  64    ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSS  123

Query  1119  LGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPD  1175
              G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +N+ G  VGPI +P 
Sbjct  124   SGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  183

Query  1176  ITIPGIPLSLNALG--GVGPITVPGVPISRIPLTINIRI----PVNITLN----ELPFNV  1225
             IT+  I L L+A     VG I++P  P++     +N  +    P +I++     E+P   
Sbjct  184   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  243

Query  1226  AG---------IFTGYIGPI-------PLSTFVLGVTLAGG-------------------  1250
                          +G IGPI        L    LG+ + GG                   
Sbjct  244   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  303

Query  1251  -TLESGIQGFSVNPFGLNIP-------LSGATNAVTI--PGFAINPFGLNVPLSGGTSPV  1300
               +  G+  F+V P G ++P       + G     T+   G+++    L + + GG  P 
Sbjct  304   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF  363

Query  1301  TI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGF  1358
             T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGF
Sbjct  364   TVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGF  423

Query  1359  GNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANL  1418
             GNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N 
Sbjct  424   GNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNF  480

Query  1419  GNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  481   GNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  520


 Score =  138 bits (348),  Expect = 8e-30, Method: Compositional matrix adjust.
 Identities = 133/310 (43%), Positives = 167/310 (54%), Gaps = 51/310 (16%)

Query  432  VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLN  491
            VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLG++S+GALVGPIN+PPIT+ 
Sbjct  8    VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  67

Query  492  SIGLELSAFQV----INVGSISIPASPLA-------IGLFGVNP-TVGSIGPGSISIQLG  539
            +IGL +S+       INV  I++PA  L        +G   V P TV +IG G  S    
Sbjct  68   AIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  127

Query  540  TPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFP--  596
               I   P   P       +    +GPI       ++PAI LGI+  G L GP  + P  
Sbjct  128  VGPINVPPITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGINSTGALVGPINIPPIT  185

Query  597  ----------------DGYSLPAIPLGIDVGG--------GLGPFTVFPDGYSLPAIPLG  632
                               S+PA PL I + G        G G  ++      +PAIP  
Sbjct  186  LNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPF  245

Query  633  --------IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP--ITIPSIPLGID  682
                    + V G +GP T    GYSLPAIPLGIDVGG +GP T  P   ++P+IPLGID
Sbjct  246  FPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGID  305

Query  683  VSGSLGPINI  692
            V G LGP  +
Sbjct  306  VGGGLGPFTV  315


 Score = 97.8 bits (242),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 106/253 (42%), Positives = 146/253 (58%), Gaps = 54/253 (21%)

Query  449  INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSI  508
            ++SSGALVGPINVPPITVPAIGLG++S+GALVGPIN+PPIT+ +IGL +S+   + VG I
Sbjct  1    MSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL-VGPI  59

Query  509  SIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPIT  568
            ++P  P+ +      P +G +G  S    +G   +P I                      
Sbjct  60   NVP--PITV------PAIG-LGVSSSGALVGPINVPPI----------------------  88

Query  569  FLSGGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSL  626
                  ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P   ++
Sbjct  89   ------TVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITV  138

Query  627  PAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGA-IGPLTTPPITIPSIPLGIDVS  684
            PAI LG+   G L GP  V P   ++PAI LGI+  GA +GP+  PPIT+ SI  G+++S
Sbjct  139  PAIGLGVSSSGALVGPINVPP--ITVPAIGLGINSTGALVGPINIPPITLNSI--GLELS  194

Query  685  G----SLGPINIP  693
                 ++G I+IP
Sbjct  195  AFQVINVGSISIP  207


 Score = 50.4 bits (119),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 56/150 (38%), Positives = 73/150 (49%), Gaps = 18/150 (12%)

Query  260  NTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNT  319
            N G+G  GF     N    G  N G    G+ N G    G+ NT T    +G + +++++
Sbjct  447  NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLATSAFHS  502

Query  320  GIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-  369
            G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N GS N  
Sbjct  503  GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  562

Query  370  ----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
                GF N G+ N G GN G+ N G  N+G
Sbjct  563  NGSFGFGNIGSNNFGFGNVGSNNLGFANTG  592


 Score = 43.5 bits (101),  Expect = 0.28, Method: Compositional matrix adjust.
 Identities = 63/186 (34%), Positives = 87/186 (47%), Gaps = 42/186 (22%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  468
             SG  ++PA  L ++  G +GP T+     ++P I LGI+  G L GP  V P   ++PA
Sbjct  266  LSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPA  324

Query  469  IGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS  528
            I LGI+  G L GP  + P                     S+PA PL I + G       
Sbjct  325  IPLGIDVGGGL-GPFTVFP------------------DGYSLPAIPLGIDVGG-------  358

Query  529  IGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGG  588
             G G  ++      +PAI        P  + V G IGP+T  +   ++PAIPLGIDV G 
Sbjct  359  -GLGPFTVFPDGYSLPAI--------PLGIDVGGAIGPLT--TPPITIPAIPLGIDVSGS  407

Query  589  LGPFTV  594
            LGP  +
Sbjct  408  LGPINI  413


>gi|306808203|ref|ZP_07444871.1| hypothetical protein TMGG_00459 [Mycobacterium tuberculosis SUMu007]
 gi|308345416|gb|EFP34267.1| hypothetical protein TMGG_00459 [Mycobacterium tuberculosis SUMu007]
Length=897

 Score = 1536 bits (3978),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 884/886 (99%), Positives = 886/886 (100%), Gaps = 0/886 (0%)

Query  248   LGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  307
             +GNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN
Sbjct  1     MGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  60

Query  308   FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  367
             FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS
Sbjct  61    FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  120

Query  368   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN  427
             NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN
Sbjct  121   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLN  180

Query  428   GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  487
             GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP
Sbjct  181   GLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  240

Query  488   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  547
             ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP
Sbjct  241   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  300

Query  548   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  607
             PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG
Sbjct  301   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  360

Query  608   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL  667
             IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL
Sbjct  361   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPL  420

Query  668   TTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV  727
             TTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV
Sbjct  421   TTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNV  480

Query  728   GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD  787
             GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD
Sbjct  481   GSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTD  540

Query  788   SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF  847
             SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF
Sbjct  541   SQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGF  600

Query  848   GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG  907
             GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG
Sbjct  601   GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG  660

Query  908   TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN  967
             TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN
Sbjct  661   TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN  720

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
             VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN
Sbjct  721   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  780

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
             IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP
Sbjct  781   IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  840

Query  1088  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1133
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP
Sbjct  841   GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  886


 Score =  351 bits (900),  Expect = 6e-94, Method: Compositional matrix adjust.
 Identities = 282/601 (47%), Positives = 341/601 (57%), Gaps = 84/601 (13%)

Query  893   FANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGN  952
               N GNGNIGFGNTG GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN
Sbjct  1     MGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGN  60

Query  953   VGIGNSG-NYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNA  1011
              GIGNSG +YNTG+GN G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++
Sbjct  61    FGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSS  120

Query  1012  NTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVE  1071
             NTG+ N G+LNTG GN G++NTG   SG+YSNG  WRGDYQGLIG+S TL          
Sbjct  121   NTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTL----------  170

Query  1072  VNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1131
                                                 TIP   L LN LG VGPI +P IT
Sbjct  171   ------------------------------------TIPAAGLDLNGLGSVGPITIPSIT  194

Query  1132  IPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG  1189
             IP I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A  
Sbjct  195   IPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQ  254

Query  1190  --GVGPITVPGVPISRIPLTINIRI----PVNITLN----ELPFNVAG---------IFT  1230
                VG I++P  P++     +N  +    P +I++     E+P                +
Sbjct  255   VINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVS  314

Query  1231  GYIGPI-------PLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--  1279
             G IGPI        L    LG+ + GG     +   G+S+    L I + G     T+  
Sbjct  315   GQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFP  374

Query  1280  PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNL  1337
              G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL +
Sbjct  375   DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGI  434

Query  1338  TANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNA  1397
               +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N 
Sbjct  435   DVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL  494

Query  1398  LQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGA  1457
                G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    A
Sbjct  495   ---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAA  551

Query  1458  G  1458
             G
Sbjct  552   G  552


 Score =  273 bits (699),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 177/293 (61%), Positives = 209/293 (72%), Gaps = 4/293 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  602  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  661

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  662  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  720

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  721  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  780

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  781  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  840

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLE  496
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+    +E
Sbjct  841  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPWYSVE  891


 Score = 79.3 bits (194),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  814   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  870


 Score = 46.6 bits (109),  Expect = 0.040, Method: Compositional matrix adjust.
 Identities = 30/80 (38%), Positives = 46/80 (58%), Gaps = 5/80 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  807   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  861

Query  1330  IPGSPLNLTANGGLGPINIP  1349
             IPG PL+L A GG+GPI +P
Sbjct  862   IPGIPLSLNALGGVGPIVVP  881


 Score = 40.0 bits (92),  Expect = 3.4, Method: Compositional matrix adjust.
 Identities = 35/77 (46%), Positives = 43/77 (56%), Gaps = 5/77 (6%)

Query  204  LSLGLANSGFGQMGAANLGILNLGSLNPG-----GNNFGLGNVGSNNVGLGNTGNGNIGF  258
             + G+AN+G G  G  N G  NLGS N G      +N G  N G+ N G+GNTGN N G 
Sbjct  85   FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGG  144

Query  259  GNTGNGNIGFGLTGDNQ  275
             N+GN + GF   GD Q
Sbjct  145  FNSGNYSNGFFWRGDYQ  161


>gi|326903520|gb|EGE50453.1| PPE family protein [Mycobacterium tuberculosis W-148]
Length=1334

 Score = 1527 bits (3953),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 899/982 (92%), Positives = 914/982 (94%), Gaps = 49/982 (4%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  105   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  164

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  165   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  224

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  225   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  284

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  285   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  344

Query  656   LGIDVGG-------------------------AIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             LGIDVGG                         AIGPLTTPPITIP+IPLGIDVSGSLGPI
Sbjct  345   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPI  404

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  750
             NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG
Sbjct  405   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  464

Query  751   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  810
             PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND
Sbjct  465   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  524

Query  811   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  870
             GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT
Sbjct  525   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  584

Query  871   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  930
             GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS
Sbjct  585   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  644

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS
Sbjct  645   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  704

Query  991   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1050
             YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD
Sbjct  705   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  764

Query  1051  YQGLIGYSDTLSIPAIPLSVEVNGGI-----------------------GPIVVPDITIP  1087
             YQGLIGYSDTLSIPAIPLSVEVNGGI                       GPIVVPDITIP
Sbjct  765   YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  824

Query  1088  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1147
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP
Sbjct  825   GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  884

Query  1148  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  1207
             IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT
Sbjct  885   IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  944

Query  1208  INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1267
             INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN
Sbjct  945   INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1004

Query  1268  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPG  1327
             IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPG
Sbjct  1005  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPG  1064

Query  1328  FTIPGSPLNLTANGGLGPINIP  1349
             F I    LN+  +GG   + IP
Sbjct  1065  FAINPFGLNVPLSGGTNAVTIP  1086


 Score =  446 bits (1148),  Expect = 1e-122, Method: Compositional matrix adjust.
 Identities = 300/469 (64%), Positives = 327/469 (70%), Gaps = 71/469 (15%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG
Sbjct  867   ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  926

Query  1121  GVGPIVVPDITIPGIPLS----------LNAL---------GGVGPIVVPD---------  1152
             GVGPI VP + I  IPL+          LN L         G +GPI +           
Sbjct  927   GVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAG  986

Query  1153  ---------------------------ITIPGI---PLSLNA--LGGVGPIVVPDITIPG  1180
                                        +TIPG    P  LN    GG  P+ +P   I  
Sbjct  987   GTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINP  1046

Query  1181  IPLSLNALGGVGPITVPGVPIS----RIPL---TINIRIPVNITLNELPFNV---AGIFT  1230
               L +   GG   +T+PG  I+     +PL   T  + IP    +N    NV    G   
Sbjct  1047  FGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIP-GFAINPFGLNVPLSGGTNA  1105

Query  1231  GYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLN  1290
               I    ++ F L V L+GGT    I GF++NPFGL++PLSG T+ VTIPGFAINPFGLN
Sbjct  1106  VTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLN  1165

Query  1291  VPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPI  1350
             VPLSGGT+ VTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPI
Sbjct  1166  VPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPI  1225

Query  1351  NITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQ  1410
             NITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQ
Sbjct  1226  NITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQ  1285

Query  1411  LASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             LASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1286  LASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1334


 Score =  303 bits (777),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 220/435 (51%), Positives = 268/435 (62%), Gaps = 56/435 (12%)

Query  206  LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  264
            +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  564  IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  623

Query  265  NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  324
            NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  624  NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  682

Query  325  GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  384
            G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  683  GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  742

Query  385  GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  444
            G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP 
Sbjct  743  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  802

Query  445  IGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---Q  501
            I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     
Sbjct  803  IPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVG  860

Query  502  VINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTV  560
             I V  I+IP  PL++  L GV P V              P+I                 
Sbjct  861  PIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI-----------------  890

Query  561  SGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVF  620
                          ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP TV 
Sbjct  891  --------------TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPITV-  933

Query  621  PDGYSLPAIPLGIDV  635
              G  +  IPL I++
Sbjct  934  -PGVPISRIPLTINI  947


 Score =  175 bits (444),  Expect = 6e-41, Method: Compositional matrix adjust.
 Identities = 185/460 (41%), Positives = 246/460 (54%), Gaps = 65/460 (14%)

Query  1061  LSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNA  1118
             +++PAI L V  +G  +GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++
Sbjct  57    ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSS  116

Query  1119  LGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPD  1175
              G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +N+ G  VGPI +P 
Sbjct  117   SGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPP  176

Query  1176  ITIPGIPLSLNALG--GVGPITVPGVPISRIPLTINIRI----PVNITLN----ELPFNV  1225
             IT+  I L L+A     VG I++P  P++     +N  +    P +I++     E+P   
Sbjct  177   ITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIP  236

Query  1226  AG---------IFTGYIGPI-------PLSTFVLGVTLAGG-------------------  1250
                          +G IGPI        L    LG+ + GG                   
Sbjct  237   PFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  296

Query  1251  -TLESGIQGFSVNPFGLNIP-------LSGATNAVTI--PGFAINPFGLNVPLSGGTSPV  1300
               +  G+  F+V P G ++P       + G     T+   G+++    L + + GG  P 
Sbjct  297   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF  356

Query  1301  TI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGF  1358
             T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGF
Sbjct  357   TVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGF  416

Query  1359  GNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANL  1418
             GNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N 
Sbjct  417   GNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNF  473

Query  1419  GNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  474   GNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  513


 Score = 80.1 bits (196),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 105/333 (32%), Positives = 164/333 (50%), Gaps = 60/333 (18%)

Query  1076  IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIP  1133
             +GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P
Sbjct  1     MGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  60

Query  1134  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1190
              I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  61    AIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  120

Query  1191  VGPITVPGVPISRIPLTIN----IRIPVNITLNELP-----FNVAGIFTGYIGPIPLSTF  1241
             VGPI VP + +  I L ++    +  P+N+    +P      N  G   G I   P++  
Sbjct  121   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLN  180

Query  1242  VLGVTLAG------GTLESGIQGFSVNPFGLN----------------------------  1267
              +G+ L+       G++       ++  FG+N                            
Sbjct  181   SIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFP  240

Query  1268  ------IPLSGATNAVTIP--GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLS  1317
                   + +SG    +T    G+++    L + + GG  P T+   G+++    L + + 
Sbjct  241   GFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVG  300

Query  1318  GGTSPVTI--PGFTIPGSPLNLTANGGLGPINI  1348
             GG  P T+   G+++P  PL +   GGLGP  +
Sbjct  301   GGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  333


 Score = 50.8 bits (120),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 56/150 (38%), Positives = 73/150 (49%), Gaps = 18/150 (12%)

Query  260  NTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNT  319
            N G+G  GF     N    G  N G    G+ N G    G+ NT T    +G + +++++
Sbjct  440  NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLATSAFHS  495

Query  320  GIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-  369
            G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N GS N  
Sbjct  496  GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  555

Query  370  ----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
                GF N G+ N G GN G+ N G  N+G
Sbjct  556  NGSFGFGNIGSNNFGFGNVGSNNLGFANTG  585


 Score = 43.1 bits (100),  Expect = 0.35, Method: Compositional matrix adjust.
 Identities = 63/186 (34%), Positives = 87/186 (47%), Gaps = 42/186 (22%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  468
             SG  ++PA  L ++  G +GP T+     ++P I LGI+  G L GP  V P   ++PA
Sbjct  259  LSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPA  317

Query  469  IGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGS  528
            I LGI+  G L GP  + P                     S+PA PL I + G       
Sbjct  318  IPLGIDVGGGL-GPFTVFP------------------DGYSLPAIPLGIDVGG-------  351

Query  529  IGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGG  588
             G G  ++      +PAI        P  + V G IGP+T  +   ++PAIPLGIDV G 
Sbjct  352  -GLGPFTVFPDGYSLPAI--------PLGIDVGGAIGPLT--TPPITIPAIPLGIDVSGS  400

Query  589  LGPFTV  594
            LGP  +
Sbjct  401  LGPINI  406


>gi|339298476|gb|AEJ50586.1| PPE family protein [Mycobacterium tuberculosis CCDC5180]
Length=1707

 Score = 1454 bits (3764),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 906/1161 (79%), Positives = 939/1161 (81%), Gaps = 166/1161 (14%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  595   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  654

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  655   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  714

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  715   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  774

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  775   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  834

Query  656   LGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFN  715
             LGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFN
Sbjct  835   LGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFN  894

Query  716   SGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLA  775
             SGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLA
Sbjct  895   SGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLA  954

Query  776   TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  835
             TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF
Sbjct  955   TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  1014

Query  836   GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFAN  895
             GSGN          IG+ +FGFGN+GSN                N GFGN+G NN GFAN
Sbjct  1015  GSGN----------IGNGSFGFGNIGSN----------------NFGFGNVGSNNLGFAN  1048

Query  896   IGNG------NIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSG  949
              G G      NIGFGN G  N            +G  N G+GNIGF N+G GNIG   +G
Sbjct  1049  TGPGLTEALHNIGFGNIGGNN------------YGFANIGNGNIGFGNTGTGNIGIGLTG  1096

Query  950   NGNVGIG--NSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLN  1007
             +  VG G  NSG+ N G  N GN N G FN+GN N GIGN+G+YNTG  N G        
Sbjct  1097  DNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVG--------  1148

Query  1008  PGNANTGYLNLG----------------------------------------DLNTGWGN  1027
               NANTG  N G                                        DLNTGWGN
Sbjct  1149  --NANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1206

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
             IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP
Sbjct  1207  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1266

Query  1088  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1147
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP
Sbjct  1267  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGP  1326

Query  1148  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  1207
             IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT
Sbjct  1327  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT  1386

Query  1208  INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1267
             INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN
Sbjct  1387  INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1446

Query  1268  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPG  1327
             IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIPG
Sbjct  1447  IPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPG  1506

Query  1328  F------------------TIPGSPLN----------------------------LTANG  1341
             F                  TIPG  +N                            +  +G
Sbjct  1507  FAINPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLDVPLSG  1566

Query  1342  GLGPINI--------PINITSAPGFG------NSTTTP---------SSGFFNSGDGSAS  1378
             G  P+ I        P+N+T+  G G      N T+ P         SSGFFNSGDGSAS
Sbjct  1567  GTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSAS  1626

Query  1379  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1438
             GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF
Sbjct  1627  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1686

Query  1439  NSGVNNIGQMLLGFFSPGAGP  1459
             NSGVNNIGQMLLGFFSPGAGP
Sbjct  1687  NSGVNNIGQMLLGFFSPGAGP  1707


 Score =  842 bits (2176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/698 (81%), Positives = 596/698 (86%), Gaps = 49/698 (7%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12   MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  432  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  491

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
            GPIN+PPIT+ +IGL +S+   + VG I++P  P+ +      P +G +G  S    +G 
Sbjct  492  GPINVPPITVPAIGLGVSSSGAL-VGPINVP--PITV------PAIG-LGVSSSGALVGP  541

Query  541  PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPDGY  599
              +P I                            ++PAI LG+   G L GP  V P   
Sbjct  542  INVPPI----------------------------TVPAIGLGVSSSGALVGPINVPP--I  571

Query  600  SLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLG  657
            ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P   ++PAI LG
Sbjct  572  TVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLG  627

Query  658  IDVGGA-IGPLTTPPITIPSIPLGIDVSGSL-GPINIP  693
            +   GA +GP+  PPIT+P+I LGI+ +G+L GPINIP
Sbjct  628  VSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIP  665


 Score =  319 bits (817),  Expect = 3e-84, Method: Compositional matrix adjust.
 Identities = 241/500 (49%), Positives = 308/500 (62%), Gaps = 34/500 (6%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  216   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  274

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  275   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  334

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  335   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  394

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  395   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  454

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  455   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  514

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + + 
Sbjct  515   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  574

Query  1203  RIPLTIN----IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTL-ESGIQ  1257
              I L ++    +  P+N+                  PI +    LGV+ +G  +    + 
Sbjct  575   AIGLGVSSSGALVGPINVP-----------------PITVPAIGLGVSSSGALVGPINVP  617

Query  1258  GFSVNPFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVP  1315
               +V   GL +  SGA    + +P   +   GL +  +G    P+ IP   +N  GL + 
Sbjct  618   PITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLEL-  676

Query  1316  LSGGTSPVTIPGFTIPGSPL  1335
                    + +   +IP SPL
Sbjct  677   --SAFQVINVGSISIPASPL  694


 Score =  315 bits (808),  Expect = 3e-83, Method: Compositional matrix adjust.
 Identities = 304/737 (42%), Positives = 373/737 (51%), Gaps = 165/737 (22%)

Query  215   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFG---------------  259
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFG               
Sbjct  983   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  1042

Query  260   -------------------------------NTGNGNIGF----------GLTGDNQQGF  278
                                            N GNGNIGF          GLTGDNQ GF
Sbjct  1043  NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  1102

Query  279   GGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIAN  338
             G  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN G ANTG FN G  N
Sbjct  1103  GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNVGNANTGLFNTGNVN  1161

Query  339   TGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYS  398
             TGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN G++NTG   SG+YS
Sbjct  1162  TGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYS  1221

Query  399   NGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  458
             NG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP I L +N+ G  VGP
Sbjct  1222  NGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGG-VGP  1280

Query  459   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---QVINVGSISIPASPL  515
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A      I V  I+IP  PL
Sbjct  1281  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1339

Query  516   AI-GLFGVNPTV----------------GSIGPGSISIQLGTPEIPAIPPFFPGFPPDYV  558
             ++  L GV P V                G +GP ++    G P I  IP       P  +
Sbjct  1340  SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVP---GVP-ISRIPLTINIRIPVNI  1395

Query  559   TV-----------SGQIGPI---TFLSG-------------GYSLPAIPLGIDVGGGLGP  591
             T+           +G IGPI   TF+ G             G+S+    L I + G    
Sbjct  1396  TLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNA  1455

Query  592   FTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSL  651
              T+   G+++    L + + GG  P T+   G+++    L + + GG    T+   G+++
Sbjct  1456  VTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLDVPLSGGTNAVTI--PGFAI  1509

Query  652   PAIPLGIDVGGAIGPLTTP------------------PITIPSI---PLGIDV--SGSLG  688
                 L + + G    +T P                   +TIP     P G+DV  SG   
Sbjct  1510  NPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLDVPLSGGTS  1569

Query  689   PINIP-IEIAGTP-------GFG------NSTTTPSSG---------FFNSGTGGTSGFG  725
             P+ IP   I G+P       G G      N T+ P  G         FFNSG G  SGFG
Sbjct  1570  PVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFG  1629

Query  726   NVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSG  782
             NVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SG
Sbjct  1630  NVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSG  1689

Query  783   VGNTDSQLAGFMRNAAG  799
             V N    L GF    AG
Sbjct  1690  VNNIGQMLLGFFSPGAG  1706


>gi|121637822|ref|YP_978045.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224990306|ref|YP_002644993.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|121493469|emb|CAL71942.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224773419|dbj|BAH26225.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341601849|emb|CCC64523.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=1835

 Score = 1415 bits (3664),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 841/984 (86%), Positives = 863/984 (88%), Gaps = 97/984 (9%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLG++S
Sbjct  608   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSS  667

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             +GALVGPIN+PPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  668   SGALVGPINVPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  727

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  728   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  787

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  788   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  847

Query  656   LGIDVGG--------------------------------------------------AIG  665
             LGIDVGG                                                  AIG
Sbjct  848   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIG  907

Query  666   PLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG  725
             PLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG
Sbjct  908   PLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG  967

Query  726   NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN  785
             NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN
Sbjct  968   NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN  1027

Query  786   TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF  845
             TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF
Sbjct  1028  TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF  1087

Query  846   GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN  905
             GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN
Sbjct  1088  GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN  1147

Query  906   TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL  965
             TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL
Sbjct  1148  TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL  1207

Query  966   GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW  1025
             GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW
Sbjct  1208  GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW  1267

Query  1026  GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT  1085
             GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT
Sbjct  1268  GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT  1327

Query  1086  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1145
             IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV
Sbjct  1328  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1387

Query  1146  GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIP  1205
             GPI VP + I  IPL+                                            
Sbjct  1388  GPITVPGVPISRIPLT--------------------------------------------  1403

Query  1206  LTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFG  1265
               INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFG
Sbjct  1404  --INIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFG  1461

Query  1266  LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTI  1325
             LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTI
Sbjct  1462  LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTI  1521

Query  1326  PGFTIPGSPLNLTANGGLGPINIP  1349
             PGF I    L++  +GG   + IP
Sbjct  1522  PGFAINPFGLDVPLSGGTNAVTIP  1545


 Score =  845 bits (2184),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 570/700 (82%), Positives = 608/700 (87%), Gaps = 29/700 (4%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  480

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPL-AIGLFGVNPTVGSIGPGSISIQLG  539
            GPIN+PPIT+ +IGL +S+   + VG I++P   + AIGL GV+ +   +GP    I + 
Sbjct  481  GPINVPPITVPAIGLGVSSSGAL-VGPINVPPITVPAIGL-GVSSSGALVGP----INVP  534

Query  540  TPEIPAIPPFFPGFPPDYVTVSGQ-IGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPD  597
               +PAI     G     V+ SG  +GPI       ++PAI LG+   G L GP  V P 
Sbjct  535  PITVPAI-----GL---GVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP-  583

Query  598  GYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIP  655
              ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P   ++PAI 
Sbjct  584  -ITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITVPAIG  638

Query  656  LGIDVGGA-IGPLTTPPITIPSIPLGIDVSGSL-GPINIP  693
            LG+   GA +GP+  PPIT+P+I LG+  SG+L GPIN+P
Sbjct  639  LGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVP  678


 Score =  323 bits (828),  Expect = 1e-85, Method: Compositional matrix adjust.
 Identities = 246/511 (49%), Positives = 310/511 (61%), Gaps = 47/511 (9%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  205   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  444   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  503

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + + 
Sbjct  504   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  563

Query  1203  RIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVN  1262
              I L ++                       +GPI                   +   +V 
Sbjct  564   AIGLGVSSS------------------GALVGPI------------------NVPPITVP  587

Query  1263  PFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVPLSGG-  1319
               GL +  SGA    + +P   +   GL V  SG    P+ +P   +   GL V  SG  
Sbjct  588   AIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  647

Query  1320  TSPVTIPGFTIPGSPLNLTANGGL-GPINIP  1349
               P+ +P  T+P   L ++++G L GPIN+P
Sbjct  648   VGPINVPPITVPAIGLGVSSSGALVGPINVP  678


 Score =  285 bits (728),  Expect = 6e-74, Method: Compositional matrix adjust.
 Identities = 187/325 (58%), Positives = 221/325 (68%), Gaps = 11/325 (3%)

Query  198   KGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGG------NNFGLGNVGSNNVGLGNT  251
              G + N S G  N G    G  N+G  NLG  N G       +N G GN+G NN G  N 
Sbjct  1079  SGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANI  1138

Query  252   GNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIG  311
             GNGNIGFGNTG GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIG
Sbjct  1139  GNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIG  1198

Query  312   NSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGF  371
             NSG +YNTG+GN G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+
Sbjct  1199  NSG-NYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGY  1257

Query  372   FNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGS  431
              N G+LNTG GN G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G 
Sbjct  1258  LNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGG  1317

Query  432   VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLN  491
             +GPI +P ITIP I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+ 
Sbjct  1318  IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIP  1375

Query  492   SIGLELSAFQVINVGSISIPASPLA  516
              I L L+A     VG I++P  P++
Sbjct  1376  GIPLSLNALG--GVGPITVPGVPIS  1398


 Score =  164 bits (416),  Expect = 8e-38, Method: Compositional matrix adjust.
 Identities = 216/621 (35%), Positives = 295/621 (48%), Gaps = 100/621 (16%)

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIG------------  851
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFGN G            
Sbjct  215   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDN  274

Query  852   --------------------SNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNY  891
                                 + N G GN G+ N G  N+G       +N G GN G  N 
Sbjct  275   QQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSG-----TSYNTGIGNTGQANT  329

Query  892   GFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNG  951
             GF N G  N G GNTG  N             G+ N GS N G FN+G+ N GFFN GN 
Sbjct  330   GFFNAGIANTGIGNTGNYNT------------GSFNLGSFNTGDFNTGSSNTGFFNPGNL  377

Query  952   NVGIGNSGNYNTGLGNVGNANTGLFNTGNVN------------------TGIGNAGSYNT  993
             N G+GN+GN NTG  N GN + G F  G+                     G+G+ G    
Sbjct  378   NTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITI  437

Query  994   GSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALIS---------GSYSNG  1044
              S    +   G +N   A  G +N+  +      +G  ++GAL+           +   G
Sbjct  438   PSITIPEIGLG-INSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLG  496

Query  1045  ILWRGDYQGLIGYSDTLSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPI  1102
             +   G   G I     +++PAI L V  +G  +GPI VP IT+P I L +++ G  VGPI
Sbjct  497   VSSSGALVGPINVPP-ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPI  555

Query  1103  VVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPL  1160
              VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L
Sbjct  556   NVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGL  615

Query  1161  SLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTIN----IRIPV  1214
              +++ G  VGPI VP IT+P I L +++ G  VGPI VP + +  I L ++    +  P+
Sbjct  616   GVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPI  675

Query  1215  N---ITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLS  1271
             N   ITLN +   ++      +G I +    L + L G     G    S+ P  ++I L 
Sbjct  676   NVPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVG----SIGPGSISIQL-  730

Query  1272  GATNAVTIPGFAINPFGLNVPLSGGTSPVTIP--GFAINPFGLNVPLSGGTSPVTI--PG  1327
             G      IP F        V +SG   P+T    G+++    L + + GG  P T+   G
Sbjct  731   GTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDG  790

Query  1328  FTIPGSPLNLTANGGLGPINI  1348
             +++P  PL +   GGLGP  +
Sbjct  791   YSLPAIPLGIDVGGGLGPFTV  811


 Score =  159 bits (402),  Expect = 4e-36, Method: Compositional matrix adjust.
 Identities = 177/450 (40%), Positives = 227/450 (51%), Gaps = 92/450 (20%)

Query  1061  LSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNA  1118
             +++PAI L V  +G  +GPI VP IT+P I L +++ G  VGPI VP IT+  I L L+A
Sbjct  632   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITLNSIGLELSA  691

Query  1119  LGGVGPIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI------------  1153
                   I V  I+IP  PL++  L GV P V              P+I            
Sbjct  692   FQ---VINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPP  747

Query  1154  -------------------TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVG  1192
                                ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+G
Sbjct  748   DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG  807

Query  1193  PITV--PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGG  1250
             P TV   G  +  IPL I++                G FT +     L    LG+ + GG
Sbjct  808   PFTVFPDGYSLPAIPLGIDVG------------GGLGPFTVFPDGYSLPAIPLGIDVGGG  855

Query  1251  TLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI--PGFAIN  1308
                  +  F+V P G ++P             AI P G++V   GG  P T+   G+++ 
Sbjct  856   -----LGPFTVFPDGYSLP-------------AI-PLGIDV--GGGLGPFTVFPDGYSLP  894

Query  1309  PFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSG  1368
                L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSG
Sbjct  895   AIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSG  954

Query  1369  FFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNT  1428
             FFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NT
Sbjct  955   FFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNT  1011

Query  1429  STVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             ST+G  T+AF+SGV N    L GF    AG
Sbjct  1012  STLGLATSAFHSGVGNTDSQLAGFMRNAAG  1041


>gi|289570001|ref|ZP_06450228.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289543755|gb|EFD47403.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=1833

 Score = 1399 bits (3622),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 912/1238 (74%), Positives = 959/1238 (78%), Gaps = 118/1238 (9%)

Query  207   GLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNI  266
             G AN+GF   G AN GI N G+ N G  N     +GS N G  NTG+ N GF N GN N 
Sbjct  302   GQANTGFFNAGIANTGIGNTGNYNTGSFN-----LGSFNTGDFNTGSSNTGFFNPGNLNT  356

Query  267   GFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQ  326
             G G TG+   G  G+NSG  + G F  G     IG +GT    I  +G   N G+G+ G 
Sbjct  357   GVGNTGNVNTG--GFNSGNYSNGFFWRGDYQGLIGFSGT--LTIPAAGLDLN-GLGSVGP  411

Query  327   ANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGN  386
                          GI ++G    G  N+          G S++G              G 
Sbjct  412   ITIPSITIPEIGLGINSSGAL-VGPINVPPITVPAIGLGVSSSGAL-----------VGP  459

Query  387   VNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGS-VGPITIPSITIPEI  445
             +N           G    G   G I     +T+PA GL ++  G+ VGPI +P IT+P I
Sbjct  460   INVPPITVPAIGLGVSSSGALVGPINVP-PITVPAIGLGVSSSGALVGPINVPPITVPAI  518

Query  446   GLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV  505
             GLG++SSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV
Sbjct  519   GLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV  578

Query  506   GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
             GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG
Sbjct  579   GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  638

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
             PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  639   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  698

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG-----------------------  662
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG                       
Sbjct  699   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  758

Query  663   --AIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
               AIGPLTTPPITIP+IPLGIDVSG LGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  759   GGAIGPLTTPPITIPAIPLGIDVSGRLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  818

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  819   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  878

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  879   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  938

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  939   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  998

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  999   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  1058

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  1059  YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1118

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1119  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1178

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1179  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1238

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI VP + 
Sbjct  1239  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1298

Query  1201  ISRIPLTIN------------IRIP-VNITLNEL----PFNVAGIFT----------GYI  1233
             I  IPL++N            I IP + ++LN L    P  V  I            G +
Sbjct  1299  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1358

Query  1234  GPI-----PLSTFVLGVTL--------------AGGTLESGIQGFSVNPFGLNIPLSGAT  1274
             GPI     P+S   L + +                G     I    ++ F L + L+G T
Sbjct  1359  GPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGT  1418

Query  1275  -----------------------NAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFG  1311
                                    NAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFG
Sbjct  1419  LESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFG  1478

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+VPLSGGT+ VTIPGF I    L++  +GG   + IP
Sbjct  1479  LDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIP  1516


 Score =  395 bits (1016),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 327/720 (46%), Positives = 409/720 (57%), Gaps = 114/720 (15%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  182   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  480

Query  1145  VGPIVVPDITIPGI-----------------PLSLNALGG--------VGPIVVPDITIP  1179
             VGPI VP IT+P I                 P+++ A+G         VGPI VP IT+P
Sbjct  481   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  540

Query  1180  GI-----------------PLSLNALG---------GVGPITVPGVPISRIPLTINIRI-  1212
              I                 P++LN++G          VG I++P  P++     +N  + 
Sbjct  541   AIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVG  600

Query  1213  ---PVNITLN----ELPFNVAG---------IFTGYIGPI-------PLSTFVLGVTLAG  1249
                P +I++     E+P                +G IGPI        L    LG+ + G
Sbjct  601   SIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGG  660

Query  1250  G--------------------TLESGIQGFSVNPFGLNIP-------LSGATNAVTI--P  1280
             G                     +  G+  F+V P G ++P       + G     T+   
Sbjct  661   GLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  720

Query  1281  GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLT  1338
             G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL + 
Sbjct  721   GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGID  780

Query  1339  ANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNAL  1398
              +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N  
Sbjct  781   VSGRLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  839

Query  1399  QGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  840   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  897


 Score =  387 bits (994),  Expect = 9e-105, Method: Compositional matrix adjust.
 Identities = 249/411 (61%), Positives = 283/411 (69%), Gaps = 19/411 (4%)

Query  1054  LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1108
             L G ++ ++IP        L+V ++GG  P+ +P   I    L +   GG   + +P   
Sbjct  1437  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFA  1496

Query  1109  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1168
             I    L +   GG   + +P   I    L +   GG   + +P   I    L +   GG 
Sbjct  1497  INPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGT  1556

Query  1169  GPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGI  1228
               + +P   I    L +   GG  P+T+PG  I+   L       V ++    P  + G 
Sbjct  1557  NAVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLD------VPLSGGTSPVTIPGF  1610

Query  1229  FTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFG  1288
                      ++ F L V L+GGT    I GF++NPFGLN+PLSG TNAVTIPGFAINPFG
Sbjct  1611  --------AINPFGLDVPLSGGTSPVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFG  1662

Query  1289  LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI  1348
             LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI
Sbjct  1663  LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI  1722

Query  1349  PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV  1408
             PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV
Sbjct  1723  PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV  1782

Query  1409  GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1783  GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1833


 Score =  146 bits (369),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 150/410 (37%), Positives = 205/410 (50%), Gaps = 34/410 (8%)

Query  410   LIGFSGTLTIPAAGLDLNGL-----GSVGPITIPSITIPEIGLGINSSGALVGPINVPPI  464
             L G +  +TIP   ++  GL     G   P+TIP   I   GL +  SG     + +P  
Sbjct  1437  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGG-TNAVTIPGF  1495

Query  465   TVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVN-  523
              +   GL +  +G     + IP   +N  GL++      N  +++IP    AI  FG++ 
Sbjct  1496  AINPFGLDVPLSGG-TNAVTIPGFAINPFGLDVPLSGGTN--AVTIPG--FAINPFGLDV  1550

Query  524   PTVG----------SIGPGSISIQLGTPEIPAIPPFFPGFPPDY-VTVSGQIGPITFLSG  572
             P  G          +I P  + + L     P   P F   P    V +SG   P+T    
Sbjct  1551  PLSGGTNAVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIP--  1608

Query  573   GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  632
             G+++    L + + GG  P T+   G+++    L + + GG    T+   G+++    L 
Sbjct  1609  GFAINPFGLDVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTNAVTI--PGFAINPFGLN  1664

Query  633   IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINI  692
             + + GG  P T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINI
Sbjct  1665  VPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI  1722

Query  693   PIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNV  749
             PI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NV
Sbjct  1723  PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV  1782

Query  750   GPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
             G L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  1783  GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1832


>gi|289443397|ref|ZP_06433141.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289416316|gb|EFD13556.1| PPE family protein [Mycobacterium tuberculosis T46]
Length=1810

 Score = 1387 bits (3589),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 907/1241 (74%), Positives = 957/1241 (78%), Gaps = 124/1241 (9%)

Query  207   GLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNI  266
             G AN+GF   G AN GI N G+ N G  N     +GS N G  NTG+ N GF N GN N 
Sbjct  325   GQANTGFFNAGIANTGIGNTGNYNTGSFN-----LGSFNTGDFNTGSSNTGFFNPGNLNT  379

Query  267   GFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQ  326
             G G TG+   G  G+NSG  + G F  G     IG +GT    I  +G   N G+G+ G 
Sbjct  380   GVGNTGNVNTG--GFNSGNYSNGFFWRGDYQGLIGFSGT--LTIPAAGLDLN-GLGSVGP  434

Query  327   ANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGN  386
                          GI ++G    G  N+          G S++G              G 
Sbjct  435   ITIPSITIPEIGLGINSSGAL-VGPINVPPITVPAIGLGVSSSGAL-----------VGP  482

Query  387   VNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGS-VGPITIPSITIPEI  445
             +N           G    G   G I     +T+PA GL ++  G+ VGPI +P IT+P I
Sbjct  483   INVPPITVPAIGLGVSSSGALVGPINVP-PITVPAIGLGVSSSGALVGPINVPPITVPAI  541

Query  446   GLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV  505
             GLG++SSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV
Sbjct  542   GLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV  601

Query  506   GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
             GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG
Sbjct  602   GSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  661

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
             PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  662   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  721

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG-----------------------  662
             LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG                       
Sbjct  722   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  781

Query  663   --AIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
               AIGPLTTPPITIP+IPLGIDVSG LGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  782   GGAIGPLTTPPITIPAIPLGIDVSGRLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  841

Query  721   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  780
             TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH
Sbjct  842   TSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFH  901

Query  781   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  840
             SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI
Sbjct  902   SGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNI  961

Query  841   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  900
             GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN
Sbjct  962   GNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGN  1021

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN
Sbjct  1022  IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  1081

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD
Sbjct  1082  YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1141

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV
Sbjct  1142  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1201

Query  1081  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1140
             VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN
Sbjct  1202  VPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  1261

Query  1141  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVP  1200
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI VP + 
Sbjct  1262  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  1321

Query  1201  ISRIPLTIN-------IRIPVNITLNELPFNVAGIFTGYIGP----------IPLSTFVL  1243
             I  IPL++N       I +P +IT+  +P ++  +  G +GP          IPLS   L
Sbjct  1322  IPGIPLSLNALGGVGPIVVP-DITIPGIPLSLNAL--GGVGPIVVPDITIPGIPLSLNAL  1378

Query  1244  G---------VTLAGGTLESGIQG-----------FSVNPFGLN----------------  1267
             G         +T+ G  L     G            S  P  +N                
Sbjct  1379  GGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNV  1438

Query  1268  ----------IPLSGATNAVTIPG---------FAINPFGLNVPLSGGTSPVTIPGFAIN  1308
                       IPLS     VT+ G         F++NPFGLN+PLSG T+ VTIPGFAIN
Sbjct  1439  AGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAIN  1498

Query  1309  PFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             PFGLNVPLSGGTSPVTIPGF I    L++  +GG   + IP
Sbjct  1499  PFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIP  1539


 Score =  465 bits (1197),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 263/289 (92%), Positives = 273/289 (95%), Gaps = 0/289 (0%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG
Sbjct  1274  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1333

Query  1121  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1180
             GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG
Sbjct  1334  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1393

Query  1181  IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST  1240
             IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST
Sbjct  1394  IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST  1453

Query  1241  FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPV  1300
             FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPV
Sbjct  1454  FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPV  1513

Query  1301  TIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             TIPGFAINPFGL+VPLSGGT+ VTIPGF I    L++  +GG   + IP
Sbjct  1514  TIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIP  1562


 Score =  457 bits (1175),  Expect = 8e-126, Method: Compositional matrix adjust.
 Identities = 302/468 (65%), Positives = 328/468 (71%), Gaps = 69/468 (14%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG
Sbjct  1343  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1402

Query  1121  GVGPIVVPDITIPGIPLS----------LNAL---------GGVGPIVVPD---------  1152
             GVGPI VP + I  IPL+          LN L         G +GPI +           
Sbjct  1403  GVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAG  1462

Query  1153  ---------------------------ITIPGI---PLSLNA--LGGVGPIVVPDITIPG  1180
                                        +TIPG    P  LN    GG  P+ +P   I  
Sbjct  1463  GTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINP  1522

Query  1181  IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVN-ITLNELPFNVAGIFTGYIG-----  1234
               L +   GG   +T+PG  I+   L + +    N +T+     N  G+     G     
Sbjct  1523  FGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAV  1582

Query  1235  PIP---LSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNV  1291
              IP   ++ F L V L+GGT    I GF++NPFGLN+PLSG TNAVTIPGFAINPFGLNV
Sbjct  1583  TIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLNV  1642

Query  1292  PLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPIN  1351
             PLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPIN
Sbjct  1643  PLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPIN  1702

Query  1352  ITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQL  1411
             ITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWN VPNALQGGVSGIYNVGQL
Sbjct  1703  ITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNPVPNALQGGVSGIYNVGQL  1762

Query  1412  ASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             ASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1763  ASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1810


 Score =  395 bits (1016),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 327/720 (46%), Positives = 409/720 (57%), Gaps = 114/720 (15%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  205   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  444   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  503

Query  1145  VGPIVVPDITIPGI-----------------PLSLNALGG--------VGPIVVPDITIP  1179
             VGPI VP IT+P I                 P+++ A+G         VGPI VP IT+P
Sbjct  504   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  563

Query  1180  GI-----------------PLSLNALG---------GVGPITVPGVPISRIPLTINIRI-  1212
              I                 P++LN++G          VG I++P  P++     +N  + 
Sbjct  564   AIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVG  623

Query  1213  ---PVNITLN----ELPFNVAG---------IFTGYIGPI-------PLSTFVLGVTLAG  1249
                P +I++     E+P                +G IGPI        L    LG+ + G
Sbjct  624   SIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGG  683

Query  1250  G--------------------TLESGIQGFSVNPFGLNIP-------LSGATNAVTI--P  1280
             G                     +  G+  F+V P G ++P       + G     T+   
Sbjct  684   GLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  743

Query  1281  GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLT  1338
             G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL + 
Sbjct  744   GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGID  803

Query  1339  ANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNAL  1398
              +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N  
Sbjct  804   VSGRLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  862

Query  1399  QGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  863   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  920


 Score =  154 bits (390),  Expect = 9e-35, Method: Compositional matrix adjust.
 Identities = 171/449 (39%), Positives = 216/449 (49%), Gaps = 71/449 (15%)

Query  417   LTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVP--------------  462
             +TIP   L LN LG VGPI +P ITIP I L +N+ G  VGPI VP              
Sbjct  1366  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTINIR  1424

Query  463   -PITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQV--------INVGSISIPAS  513
              P+ +    L  N  G   G I   P++   +G+ L+   +        +N   ++IP S
Sbjct  1425  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLS  1484

Query  514   P---------LAIGLFGVN-PTVGSIGPGSIS------IQLGTP--------EIP--AIP  547
                        AI  FG+N P  G   P +I         L  P         IP  AI 
Sbjct  1485  GATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAIN  1544

Query  548   PFFPGFP----PDYVTVSG-QIGPITF---LSGGYSLPAIP------LGIDVGGGLGPFT  593
             PF    P     + VT+ G  I P      LSGG +   IP       G+DV    G   
Sbjct  1545  PFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVPLSGGTNA  1604

Query  594   VFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA  653
             V   G+++    L + + GG    T+   G+++    L + + GG  P T+   G+++  
Sbjct  1605  VTIPGFAINPFGLNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINP  1660

Query  654   IPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGF  713
               L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGF
Sbjct  1661  FGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGF  1720

Query  714   FNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTS  770
             FNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTS
Sbjct  1721  FNSGDGSASGFGNVGPGISGLWNPVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTS  1780

Query  771   TLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
             T+G  T+AF+SGV N    L GF    AG
Sbjct  1781  TVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1809


>gi|298525411|ref|ZP_07012820.1| PPE family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298495205|gb|EFI30499.1| PPE family protein [Mycobacterium tuberculosis 94_M4241A]
Length=1884

 Score = 1377 bits (3565),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 848/1053 (81%), Positives = 878/1053 (84%), Gaps = 120/1053 (11%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  561   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  620

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  621   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  680

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  681   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  740

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  741   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  800

Query  656   LGIDVGG--------------------------------------------------AIG  665
             LGIDVGG                                                  AIG
Sbjct  801   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIG  860

Query  666   PLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG  725
             PLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG
Sbjct  861   PLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFG  920

Query  726   NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN  785
             NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN
Sbjct  921   NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGN  980

Query  786   TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF  845
             TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF
Sbjct  981   TDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSF  1040

Query  846   GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN  905
             GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN
Sbjct  1041  GFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGN  1100

Query  906   TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL  965
             TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL
Sbjct  1101  TGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGL  1160

Query  966   GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW  1025
             GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW
Sbjct  1161  GNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGW  1220

Query  1026  GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT  1085
             GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT
Sbjct  1221  GNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDIT  1280

Query  1086  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1145
             IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV
Sbjct  1281  IPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGV  1340

Query  1146  GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIP  1205
             GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI VP + I  IP
Sbjct  1341  GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIP  1400

Query  1206  LTIN------------IRIP-VNITLNEL----PFNVAGIFT----------GYIGPI--  1236
             L++N            I IP + ++LN L    P  V  I            G +GPI  
Sbjct  1401  LSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITV  1460

Query  1237  ---PLSTFVLGVTL--------------AGGTLESGIQGFSVNPFGLNIPLSGAT-----  1274
                P+S   L + +                G     I    ++ F L + L+G T     
Sbjct  1461  PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGI  1520

Query  1275  ------------------NAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPL  1316
                               NAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPL
Sbjct  1521  QGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPL  1580

Query  1317  SGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             SGGT+ VTIPGF I    L++  +GG   + IP
Sbjct  1581  SGGTNAVTIPGFAINPFGLDVPLSGGTNAVTIP  1613


 Score =  796 bits (2057),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 537/675 (80%), Positives = 573/675 (85%), Gaps = 49/675 (7%)

Query  24   MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  83
            MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA
Sbjct  1    MSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQA  60

Query  84   QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  143
            QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM
Sbjct  61   QRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQM  120

Query  144  WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  203
            WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN
Sbjct  121  WAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLAN  180

Query  204  LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN
Sbjct  181  LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN
Sbjct  241  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
            TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN
Sbjct  301  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
            TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP
Sbjct  361  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
            EIGLGINSSGALVGPINVPPITVPAIGLG++S+GALVGPIN+PPIT+ +IGL +S+   +
Sbjct  421  EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  480

Query  504  NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQ  563
             VG I++P  P+ +      P +G +G  S    +G   +P I                 
Sbjct  481  -VGPINVP--PITV------PAIG-LGVSSSGALVGPINVPPI-----------------  513

Query  564  IGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFP  621
                       ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P
Sbjct  514  -----------TVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP  560

Query  622  DGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGA-IGPLTTPPITIPSIPL  679
               ++PAI LG+   G L GP  V P   ++PAI LG+   GA +GP+  PPIT+P+I L
Sbjct  561  --ITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPPITVPAIGL  616

Query  680  GIDVSGSL-GPINIP  693
            GI+ +G+L GPINIP
Sbjct  617  GINSTGALVGPINIP  631


 Score =  423 bits (1087),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 287/471 (61%), Positives = 316/471 (68%), Gaps = 75/471 (15%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS-----  1115
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL+     
Sbjct  1417  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRI  1476

Query  1116  -----LNAL---------GGVGPIVVPD--------------------------------  1129
                  LN L         G +GPI +                                  
Sbjct  1477  PVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSG  1536

Query  1130  ----ITIPGI---PLSLNA--LGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1180
                 +TIPG    P  LN    GG  P+ +P   I    L +   GG   + +P   I  
Sbjct  1537  ATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINP  1596

Query  1181  IPLSLNALGGVGPITVPGVPIS----RIPL---TINIRIPVNITLNELPFNVAGIFTGYI  1233
               L +   GG   +T+PG  I+     +PL   T  + IP    +N  PF +    +G  
Sbjct  1597  FGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIP-GFAIN--PFGLDVPLSGGT  1653

Query  1234  GPIPLSTFV-----LGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFG  1288
              P+ +  F      L V L+GGT    I GF++NPFGLN+PLSG TNAVTIPGFAINPFG
Sbjct  1654  SPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFG  1713

Query  1289  LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI  1348
             LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI
Sbjct  1714  LNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI  1773

Query  1349  PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV  1408
             PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV
Sbjct  1774  PINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNV  1833

Query  1409  GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1834  GQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1884


 Score =  317 bits (811),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 241/500 (49%), Positives = 308/500 (62%), Gaps = 34/500 (6%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  182   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  240

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  241   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  300

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  301   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  360

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  361   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  420

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  421   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  480

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + + 
Sbjct  481   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  540

Query  1203  RIPLTIN----IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTL-ESGIQ  1257
              I L ++    +  P+N+                  PI +    LGV+ +G  +    + 
Sbjct  541   AIGLGVSSSGALVGPINVP-----------------PITVPAIGLGVSSSGALVGPINVP  583

Query  1258  GFSVNPFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVP  1315
               +V   GL +  SGA    + +P   +   GL +  +G    P+ IP   +N  GL + 
Sbjct  584   PITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLEL-  642

Query  1316  LSGGTSPVTIPGFTIPGSPL  1335
                    + +   +IP SPL
Sbjct  643   --SAFQVINVGSISIPASPL  660


 Score =  302 bits (773),  Expect = 3e-79, Method: Compositional matrix adjust.
 Identities = 244/542 (46%), Positives = 300/542 (56%), Gaps = 120/542 (22%)

Query  215   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFG---------------  259
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFG               
Sbjct  999   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  1058

Query  260   -------------------------------NTGNGNIGF----------GLTGDNQQGF  278
                                            N GNGNIGF          GLTGDNQ GF
Sbjct  1059  NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  1118

Query  279   GGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIAN  338
             G  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN G ANTG FN G  N
Sbjct  1119  GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNVGNANTGLFNTGNVN  1177

Query  339   TGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYS  398
             TGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN G++NTG   SG+YS
Sbjct  1178  TGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYS  1237

Query  399   NGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  458
             NG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP I L +N+ G  VGP
Sbjct  1238  NGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGG-VGP  1296

Query  459   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---QVINVGSISIPASPL  515
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A      I V  I+IP  PL
Sbjct  1297  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1355

Query  516   AI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGY  574
             ++  L GV P V              P+I                               
Sbjct  1356  SLNALGGVGPIV-------------VPDI-------------------------------  1371

Query  575   SLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGID  634
             ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++
Sbjct  1372  TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLN  1427

Query  635   VGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPI  694
               GG+GP  V PD  ++P IPL ++  G +GP+T P + I  IPL I+       I IP+
Sbjct  1428  ALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPV  1478

Query  695   EI  696
              I
Sbjct  1479  NI  1480


 Score =  159 bits (402),  Expect = 4e-36, Method: Compositional matrix adjust.
 Identities = 177/450 (40%), Positives = 227/450 (51%), Gaps = 92/450 (20%)

Query  1061  LSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNA  1118
             +++PAI L V  +G  +GPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A
Sbjct  585   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSA  644

Query  1119  LGGVGPIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI------------  1153
                   I V  I+IP  PL++  L GV P V              P+I            
Sbjct  645   FQ---VINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPP  700

Query  1154  -------------------TIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVG  1192
                                ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+G
Sbjct  701   DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG  760

Query  1193  PITV--PGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGG  1250
             P TV   G  +  IPL I++                G FT +     L    LG+ + GG
Sbjct  761   PFTVFPDGYSLPAIPLGIDVG------------GGLGPFTVFPDGYSLPAIPLGIDVGGG  808

Query  1251  TLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI--PGFAIN  1308
                  +  F+V P G ++P             AI P G++V   GG  P T+   G+++ 
Sbjct  809   -----LGPFTVFPDGYSLP-------------AI-PLGIDV--GGGLGPFTVFPDGYSLP  847

Query  1309  PFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSG  1368
                L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSG
Sbjct  848   AIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSG  907

Query  1369  FFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNT  1428
             FFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NT
Sbjct  908   FFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNT  964

Query  1429  STVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             ST+G  T+AF+SGV N    L GF    AG
Sbjct  965   STLGLATSAFHSGVGNTDSQLAGFMRNAAG  994


 Score =  146 bits (369),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 145/380 (39%), Positives = 199/380 (53%), Gaps = 28/380 (7%)

Query  423   GLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGP  482
             GL++   G+   +TIP   I   GL +  SG    P+ +P   +   GL +  +G     
Sbjct  1529  GLNIPLSGATNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLDVPLSGG-TNA  1586

Query  483   INIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPE  542
             + IP   +N  GL++      N  +++IP    AI  FG+N  + S G  +++I    P 
Sbjct  1587  VTIPGFAINPFGLDVPLSGGTN--AVTIPG--FAINPFGLNVPL-SGGTNAVTI----PG  1637

Query  543   IPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLP  602
               AI PF    P     +SG   P+T    G+++    L + + GG  P T+   G+++ 
Sbjct  1638  F-AINPFGLDVP-----LSGGTSPVTIP--GFAINPFGLDVPLSGGTSPVTI--PGFAIN  1687

Query  603   AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG  662
                L + + GG    T+   G+++    L + + GG  P T+   G+++    L + + G
Sbjct  1688  PFGLNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSG  1743

Query  663   AIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTS  722
                P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  S
Sbjct  1744  GTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSAS  1803

Query  723   GFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAF  779
             GFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF
Sbjct  1804  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1863

Query  780   HSGVGNTDSQLAGFMRNAAG  799
             +SGV N    L GF    AG
Sbjct  1864  NSGVNNIGQMLLGFFSPGAG  1883


>gi|339631970|ref|YP_004723612.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339331326|emb|CCC27010.1| PPE family protein [Mycobacterium africanum GM041182]
Length=1838

 Score = 1353 bits (3502),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 868/1236 (71%), Positives = 923/1236 (75%), Gaps = 198/1236 (16%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLGINS+GALVGPIN+PPIT+ +IGL +++
Sbjct  608   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSA  667

Query  476   TGAL-VGPINIPPITL----------------NSIGLELSAFQVINV-------------  505
                + VG I+IP   L                 SI ++L   ++  +             
Sbjct  668   FQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVT  727

Query  506   ------------GSISIPASPLAI------GLFGVNPTVGSIGPGSISIQLG--------  539
                         G  S+PA PL I      G F V P   S+    + I +G        
Sbjct  728   VSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  787

Query  540   TPE---IPAIP----------PFFPGFPPDY--------VTVSGQIGPITFLSGGYSLPA  578
              P+   +PAIP          PF   FP  Y        + V G +GP T    GYSLPA
Sbjct  788   FPDGYSLPAIPLGIDVGGGLGPFTV-FPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA  846

Query  579   IPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGG  638
             IPLGIDV GGLGPFTVFPDGYSLPAIPLGIDV GGLGPFTVFPDGYSLPAIPLGIDVGGG
Sbjct  847   IPLGIDVCGGLGPFTVFPDGYSLPAIPLGIDVCGGLGPFTVFPDGYSLPAIPLGIDVGGG  906

Query  639   LGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAG  698
             LGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAG
Sbjct  907   LGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAG  966

Query  699   TPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILN  758
             TPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILN
Sbjct  967   TPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILN  1026

Query  759   FGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNA  818
             FGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNA
Sbjct  1027  FGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNA  1086

Query  819   NLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEAL  878
             NLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEAL
Sbjct  1087  NLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEAL  1146

Query  879   HNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNS  938
             HNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNS
Sbjct  1147  HNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNS  1206

Query  939   GNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNA  998
             GNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNA
Sbjct  1207  GNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNA  1266

Query  999   GDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYS  1058
             GDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYS
Sbjct  1267  GDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYS  1326

Query  1059  DTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNA  1118
             DTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNA
Sbjct  1327  DTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNA  1386

Query  1119  LGGVG-----------------------PIVVPD------------------ITIPGIPL  1137
             LGGVG                       PIVVPD                  IT+PG+P+
Sbjct  1387  LGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPI  1446

Query  1138  ---------------SLNAL---------GGVGPIVVPD---------------------  1152
                            +LN L         G +GPI +                       
Sbjct  1447  SRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSV  1506

Query  1153  ---------------ITIPGI---PLSLNA--LGGVGPIVVPDITIPGIPLSLNALGGVG  1192
                            +TIPG    P  LN    GG  P+ +P   I    L +   GG  
Sbjct  1507  NPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTN  1566

Query  1193  PITVPGVPISRIPLTINIRIPVN-ITLNELPFNVAGI---FTGYIGPIPLSTFV-----L  1243
              +T+PG  I+   L + +    N +T+     N  G+    +G   P+ +  F      L
Sbjct  1567  AVTIPGFAINPFGLDVPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL  1626

Query  1244  GVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIP  1303
              V L+GGT    I GF++NPFGLN+PLSG TNAVTIPGFAINPFGLNVPLSGGTSPVTIP
Sbjct  1627  NVPLSGGTSPVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIP  1686

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI    TSAPGFGNSTT
Sbjct  1687  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINI----TSAPGFGNSTT  1742

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS
Sbjct  1743  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1802

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  1803  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1838


 Score =  841 bits (2172),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/698 (81%), Positives = 596/698 (86%), Gaps = 49/698 (7%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  480

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
            GPIN+PPIT+ +IGL +S+   + VG I++P  P+ +      P +G +G  S    +G 
Sbjct  481  GPINVPPITVPAIGLGVSSSGAL-VGPINVP--PITV------PAIG-LGVSSSGALVGP  530

Query  541  PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPDGY  599
              +P I                            ++PAI LG+   G L GP  V P   
Sbjct  531  INVPPI----------------------------TVPAIGLGVSSSGALVGPINVPP--I  560

Query  600  SLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLG  657
            ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P   ++PAI LG
Sbjct  561  TVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLG  616

Query  658  IDVGGA-IGPLTTPPITIPSIPLGIDVSGSL-GPINIP  693
            +   GA +GP+  PPIT+P+I LGI+ +G+L GPINIP
Sbjct  617  VSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIP  654


 Score =  357 bits (916),  Expect = 1e-95, Method: Compositional matrix adjust.
 Identities = 221/279 (80%), Positives = 235/279 (85%), Gaps = 28/279 (10%)

Query  417  LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
            +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  584  ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  643

Query  476  TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
            TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  644  TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  703

Query  536  IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
            IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG                      
Sbjct  704  IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG----------------------  741

Query  596  PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
               YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  742  ---YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  798

Query  656  LGIDVGGAIGPLTTPP--ITIPSIPLGIDVSGSLGPINI  692
            LGIDVGG +GP T  P   ++P+IPLGIDV G LGP  +
Sbjct  799  LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  837


 Score =  318 bits (816),  Expect = 4e-84, Method: Compositional matrix adjust.
 Identities = 241/500 (49%), Positives = 308/500 (62%), Gaps = 34/500 (6%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  205   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  444   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  503

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + + 
Sbjct  504   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  563

Query  1203  RIPLTIN----IRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTL-ESGIQ  1257
              I L ++    +  P+N+                  PI +    LGV+ +G  +    + 
Sbjct  564   AIGLGVSSSGALVGPINVP-----------------PITVPAIGLGVSSSGALVGPINVP  606

Query  1258  GFSVNPFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVP  1315
               +V   GL +  SGA    + +P   +   GL +  +G    P+ IP   +N  GL + 
Sbjct  607   PITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLEL-  665

Query  1316  LSGGTSPVTIPGFTIPGSPL  1335
                    + +   +IP SPL
Sbjct  666   --SAFQVINVGSISIPASPL  683


 Score =  293 bits (749),  Expect = 2e-76, Method: Compositional matrix adjust.
 Identities = 235/519 (46%), Positives = 302/519 (59%), Gaps = 50/519 (9%)

Query  206   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  264
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  1118  IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  1177

Query  265   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  324
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  1178  NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  1236

Query  325   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  384
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  1237  GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1296

Query  385   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  444
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP 
Sbjct  1297  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1356

Query  445   IGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---Q  501
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A     
Sbjct  1357  IPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVG  1414

Query  502   VINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTV-  560
              I V  I+IP  PL++        +G +GP ++    G P I  IP       P  +T+ 
Sbjct  1415  PIVVPDITIPGIPLSLN------ALGGVGPITVP---GVP-ISRIPLTINIRIPVNITLN  1464

Query  561   ----------SGQIGPI---TFLSG-------------GYSLPAIPLGIDVGGGLGPFTV  594
                       +G IGPI   TF+ G             G+S+    L I + G     T+
Sbjct  1465  ELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTI  1524

Query  595   FPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAI  654
                G+++    L + + GG  P T+   G+++    L + + GG    T+   G+++   
Sbjct  1525  --PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLDVPLSGGTNAVTI--PGFAINPF  1578

Query  655   PLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIP  693
              L + + GA   +T P   I    L + +SG   P+ IP
Sbjct  1579  GLDVPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIP  1617


 Score = 49.7 bits (117),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 56/150 (38%), Positives = 73/150 (49%), Gaps = 18/150 (12%)

Query  260   NTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNT  319
             N G+G  GF     N    G  N G    G+ N G    G+ NT T    +G + +++++
Sbjct  994   NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLATSAFHS  1049

Query  320   GIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-  369
             G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N GS N  
Sbjct  1050  GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  1109

Query  370   ----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
                 GF N G+ N G GN G+ N G  N+G
Sbjct  1110  NGSFGFGNIGSNNFGFGNVGSNNLGFANTG  1139


 Score = 43.1 bits (100),  Expect = 0.45, Method: Compositional matrix adjust.
 Identities = 37/101 (37%), Positives = 53/101 (53%), Gaps = 29/101 (28%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITI-------PSI--------------------TIPEI  445
            F    ++PA  L ++  G +GP T+       P+I                    ++P I
Sbjct  863  FPDGYSLPAIPLGIDVCGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAI  922

Query  446  GLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIP  486
             LGI+  GA +GP+  PPIT+PAI LGI+ +G+L GPINIP
Sbjct  923  PLGIDVGGA-IGPLTTPPITIPAIPLGIDVSGSL-GPINIP  961


>gi|31793109|ref|NP_855602.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|31618700|emb|CAD94653.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
Length=1910

 Score = 1310 bits (3390),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 788/932 (85%), Positives = 811/932 (88%), Gaps = 54/932 (5%)

Query  430   GSVGPITIPS--ITIPEIGLGINSSGALVGPINVPP--ITVPAIGLGINSTGALVGPINI  485
             G +GPIT  S   ++P I LGI+  G L GP  V P   ++PAI LGI+  G L GP  +
Sbjct  754   GQIGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTV  811

Query  486   -------PPITLN-SIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQ  537
                    P I L   +G  L  F V   G  S+PA PL I + G        G G  ++ 
Sbjct  812   FPDGYSLPAIPLGIDVGGGLGPFTVFPDG-YSLPAIPLGIDVGG--------GLGPFTVF  862

Query  538   LGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPD  597
                  +PAIP          + V G +GP T    GYSLPAIPLGIDVGGGLGPFTVFPD
Sbjct  863   PDGYSLPAIP--------LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  914

Query  598   GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  657
             GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG
Sbjct  915   GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLG  974

Query  658   IDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSG  717
             IDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSG
Sbjct  975   IDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSG  1034

Query  718   TGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATS  777
             TGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATS
Sbjct  1035  TGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATS  1094

Query  778   AFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGS  837
             AFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGS
Sbjct  1095  AFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGS  1154

Query  838   GNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIG  897
             GNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIG
Sbjct  1155  GNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIG  1214

Query  898   NGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGN  957
             NGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGN
Sbjct  1215  NGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGN  1274

Query  958   SGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLN  1017
             SGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLN
Sbjct  1275  SGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLN  1334

Query  1018  LGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIG  1077
             LGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIG
Sbjct  1335  LGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIG  1394

Query  1078  PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1137
             PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL
Sbjct  1395  PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1454

Query  1138  SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVP  1197
             SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPI V                       P
Sbjct  1455  SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITV-----------------------P  1491

Query  1198  GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ  1257
             GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ
Sbjct  1492  GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQ  1551

Query  1258  GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLS  1317
             GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLS
Sbjct  1552  GFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLS  1611

Query  1318  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             GGT+ VTIPGF I    L++  +GG  P+ IP
Sbjct  1612  GGTNAVTIPGFAINPFGLDVPLSGGTSPVTIP  1643


 Score =  845 bits (2183),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 570/700 (82%), Positives = 608/700 (87%), Gaps = 29/700 (4%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  480

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPL-AIGLFGVNPTVGSIGPGSISIQLG  539
            GPIN+PPIT+ +IGL +S+   + VG I++P   + AIGL GV+ +   +GP    I + 
Sbjct  481  GPINVPPITVPAIGLGVSSSGAL-VGPINVPPITVPAIGL-GVSSSGALVGP----INVP  534

Query  540  TPEIPAIPPFFPGFPPDYVTVSGQ-IGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPD  597
               +PAI     G     V+ SG  +GPI       ++PAI LG+   G L GP  V P 
Sbjct  535  PITVPAI-----GL---GVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP-  583

Query  598  GYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIP  655
              ++PAI LG+   G L GP  V P   ++PAI LG+   G L GP  V P   ++PAI 
Sbjct  584  -ITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITVPAIG  638

Query  656  LGIDVGGA-IGPLTTPPITIPSIPLGIDVSGSL-GPINIP  693
            LG+   GA +GP+  PPIT+P+I LG+  SG+L GPIN+P
Sbjct  639  LGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVP  678


 Score =  323 bits (827),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 246/511 (49%), Positives = 309/511 (61%), Gaps = 47/511 (9%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  205   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  444   EIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  503

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + + 
Sbjct  504   VGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVP  563

Query  1203  RIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVN  1262
              I L ++    +   +N  P  V  I                                  
Sbjct  564   AIGLGVSSSGALVGPINVPPITVPAI----------------------------------  589

Query  1263  PFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVPLSGG-  1319
               GL +  SGA    + +P   +   GL V  SG    P+ +P   +   GL V  SG  
Sbjct  590   --GLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGAL  647

Query  1320  TSPVTIPGFTIPGSPLNLTANGGL-GPINIP  1349
               P+ +P  T+P   L ++++G L GPIN+P
Sbjct  648   VGPINVPPITVPAIGLGVSSSGALVGPINVP  678


 Score =  187 bits (474),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 175/409 (43%), Positives = 227/409 (56%), Gaps = 71/409 (17%)

Query  1062  SIPAIPLSVEVNGGIGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLN  1117
             S+PAIPL ++V GG+GP  V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++
Sbjct  767   SLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGID  826

Query  1118  ALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV  1173
               GG+GP  V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP  V
Sbjct  827   VGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  886

Query  1174  -PD-ITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTG  1231
              PD  ++P IPL ++  GG+GP TV                P   +L  +P         
Sbjct  887   FPDGYSLPAIPLGIDVGGGLGPFTV---------------FPDGYSLPAIP---------  922

Query  1232  YIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNV  1291
                        LG+ + GG     +  F+V P G ++P             AI P G++V
Sbjct  923   -----------LGIDVGGG-----LGPFTVFPDGYSLP-------------AI-PLGIDV  952

Query  1292  PLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
                GG  P T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINIP
Sbjct  953   --GGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIP  1010

Query  1350  INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVG  1409
             I I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG
Sbjct  1011  IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVG  1067

Query  1410  QLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
              L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  1068  PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  1116


 Score =  164 bits (416),  Expect = 1e-37, Method: Compositional matrix adjust.
 Identities = 215/617 (35%), Positives = 294/617 (48%), Gaps = 92/617 (14%)

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIG------------  851
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFGN G            
Sbjct  215   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDN  274

Query  852   --------------------SNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNY  891
                                 + N G GN G+ N G  N+G       +N G GN G  N 
Sbjct  275   QQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSG-----TSYNTGIGNTGQANT  329

Query  892   GFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNG  951
             GF N G  N G GNTG  N             G+ N GS N G FN+G+ N GFFN GN 
Sbjct  330   GFFNAGIANTGIGNTGNYNT------------GSFNLGSFNTGDFNTGSSNTGFFNPGNL  377

Query  952   NVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNP---  1008
             N G+GN+GN NTG  N GN + G F  G+    IG +G+    +        G + P   
Sbjct  378   NTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITI  437

Query  1009  GNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPL  1068
              +     + LG +N+    +G +N   +   +   G+   G   G I     +++PAI L
Sbjct  438   PSITIPEIGLG-INSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPP-ITVPAIGL  495

Query  1069  SVEVNGG-IGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPI  1125
              V  +G  +GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI
Sbjct  496   GVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPI  555

Query  1126  VVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPL  1183
              VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L
Sbjct  556   NVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGL  615

Query  1184  SLNALGG-VGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTG------YIGPI  1236
              +++ G  VGPI VP + +  I L ++    +   +N  P  V  I  G       +GPI
Sbjct  616   GVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPI  675

Query  1237  ------------PLSTFVL----GVTLAGGTLESGIQGF-----SVNPFGLNIPLSGATN  1275
                          LS F +     +++    L  G+ G      S+ P  ++I L G   
Sbjct  676   NVPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQL-GTPE  734

Query  1276  AVTIPGFAINPFGLNVPLSGGTSPVTIP--GFAINPFGLNVPLSGGTSPVTI--PGFTIP  1331
                IP F        V +SG   P+T    G+++    L + + GG  P T+   G+++P
Sbjct  735   IPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLP  794

Query  1332  GSPLNLTANGGLGPINI  1348
               PL +   GGLGP  +
Sbjct  795   AIPLGIDVGGGLGPFTV  811


 Score =  132 bits (332),  Expect = 4e-28, Method: Compositional matrix adjust.
 Identities = 140/380 (37%), Positives = 189/380 (50%), Gaps = 32/380 (8%)

Query  423   GLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGP  482
             GL++   G+   +TIP   I   GL +  SG    P+ +P   +   GL +  +G     
Sbjct  1559  GLNIPLSGATNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLDVPLSGG-TNA  1616

Query  483   INIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPE  542
             + IP   +N  GL++          +S   SP+ I  F +NP  G   P S      T  
Sbjct  1617  VTIPGFAINPFGLDVP---------LSGGTSPVTIPGFAINP-FGLDVPLSGGTNAVTIP  1666

Query  543   IPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLP  602
               AI PF    P     +SG    +T    G+++    L + + GG  P T+   G+++ 
Sbjct  1667  GFAINPFGLDVP-----LSGGTNAVTIP--GFAINPFGLDVPLSGGTSPVTI--PGFAIN  1717

Query  603   AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGG  662
                L + + GG    T+   G+++    L + + GG  P T+   G+++    L + + G
Sbjct  1718  PFDLNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSG  1773

Query  663   AIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTS  722
                P+T P  TIP  PL +  +G LGPINI       PGFGNSTTTPSSGFFNSG G  S
Sbjct  1774  GTSPVTIPGFTIPGSPLNLTANGGLGPINI----TSAPGFGNSTTTPSSGFFNSGDGSAS  1829

Query  723   GFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAF  779
             GFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF
Sbjct  1830  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1889

Query  780   HSGVGNTDSQLAGFMRNAAG  799
             +SGV N    L GF    AG
Sbjct  1890  NSGVNNIGQMLLGFFSPGAG  1909


 Score = 54.3 bits (129),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 60/156 (39%), Positives = 77/156 (50%), Gaps = 18/156 (11%)

Query  720  GTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLA  775
            G  GFGN G+G  GF     N    G  N G    G+ N G    G+ NT T    +G +
Sbjct  254  GNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNS  313

Query  776  TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  835
             +++++G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N 
Sbjct  314  GTSYNTGIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNT  364

Query  836  GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  871
            GS N      GF N G+ N G GN G+ N G  N+G
Sbjct  365  GSSNT-----GFFNPGNLNTGVGNTGNVNTGGFNSG  395


>gi|289447533|ref|ZP_06437277.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420491|gb|EFD17692.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=1346

 Score = 1262 bits (3266),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 733/777 (95%), Positives = 743/777 (96%), Gaps = 26/777 (3%)

Query  417   LTIPAAGLDLNGLGS-VGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             +T+PA GL ++  G+ VGPI +P IT+P IGLG++SSGALVGPINVPPITVPAIGLGINS
Sbjct  547   ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINS  606

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS
Sbjct  607   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  666

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  595
             IQLGTP IPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF
Sbjct  667   IQLGTPAIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVF  726

Query  596   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  655
             PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP
Sbjct  727   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIP  786

Query  656   LGIDVGG-------------------------AIGPLTTPPITIPSIPLGIDVSGSLGPI  690
             LGIDVGG                         AIGPLTTPPITIP+IPLGIDVSGSLGPI
Sbjct  787   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPI  846

Query  691   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  750
             NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG
Sbjct  847   NIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVG  906

Query  751   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  810
             PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND
Sbjct  907   PLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFAND  966

Query  811   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  870
             GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT
Sbjct  967   GTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANT  1026

Query  871   GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  930
             GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS
Sbjct  1027  GPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGS  1086

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS
Sbjct  1087  GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  1146

Query  991   YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1050
             YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD
Sbjct  1147  YNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGD  1206

Query  1051  YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1110
             YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP
Sbjct  1207  YQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIP  1266

Query  1111  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG  1167
             GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG
Sbjct  1267  GIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG  1323


 Score =  845 bits (2183),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 570/743 (77%), Positives = 608/743 (82%), Gaps = 55/743 (7%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12   MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNS TSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312  GNTGTGNFGIGNSATSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  432  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  491

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPL-AIGLFGVNPTVGSIGPGSI-----  534
            GPIN+PPIT+ +IGL +S+   + VG I++P   + AIGL GV+ +   +GP ++     
Sbjct  492  GPINVPPITVPAIGLGVSSSGAL-VGPINVPPITVPAIGL-GVSSSGALVGPINVPPITV  549

Query  535  -SIQLGTPEIPA------IPPF-FPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVG  586
             +I LG     A      +PP   P       +    +GPI       ++PAI LGI+  
Sbjct  550  PAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPP--ITVPAIGLGINST  607

Query  587  GGL-GPFTVFP------------------DGYSLPAIPLGIDVGG--------GLGPFTV  619
            G L GP  + P                     S+PA PL I + G        G G  ++
Sbjct  608  GALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISI  667

Query  620  FPDGYSLPAIPLG--------IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPP  671
                 ++PAIP          + V G +GP T    GYSLPAIPLGIDVGG +GP T  P
Sbjct  668  QLGTPAIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFP  727

Query  672  --ITIPSIPLGIDVSGSLGPINI  692
               ++P+IPLGIDV G LGP  +
Sbjct  728  DGYSLPAIPLGIDVGGGLGPFTV  750


 Score =  336 bits (862),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 313/743 (43%), Positives = 394/743 (54%), Gaps = 138/743 (18%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNS  +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSATSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG--  1026
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG G  
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1027  --------NIGDLNTGALISGSYSNGILWRG---------DYQGL---------------  1054
                     N G+ + G    G Y   I + G         D  GL               
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  455

Query  1055  --IGYSDT-----------LSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNALGG-V  1099
               +G + +           +++PAI L V  +G  +GPI VP IT+P I L +++ G  V
Sbjct  456   IGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALV  515

Query  1100  GPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPG  1157
             GPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P 
Sbjct  516   GPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPA  575

Query  1158  IPLSLNALGG-VGPIVVPDITIPGI-----------------PLSLNALG---------G  1190
             I L +++ G  VGPI VP IT+P I                 P++LN++G          
Sbjct  576   IGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVIN  635

Query  1191  VGPITVPGVPI------------SRIPLTINIR-----IPVNITLNELPFNVAGIFTGYI  1233
             VG I++P  P+            S  P +I+I+     IP                +G I
Sbjct  636   VGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPAIPAIPPFFPGFPPDYVTVSGQI  695

Query  1234  GPI-------PLSTFVLGVTLAGG--------------------TLESGIQGFSVNPFGL  1266
             GPI        L    LG+ + GG                     +  G+  F+V P G 
Sbjct  696   GPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGY  755

Query  1267  NIP-------LSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVP  1315
             ++P       + G     T+   G+++    L + + GG  P T+   G+++    L + 
Sbjct  756   SLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGID  815

Query  1316  LSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDG  1375
             + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G
Sbjct  816   VGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTG  875

Query  1376  SASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLT  1435
               SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T
Sbjct  876   GTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLAT  932

Query  1436  AAFNSGVNNIGQMLLGFFSPGAG  1458
             +AF+SGV N    L GF    AG
Sbjct  933   SAFHSGVGNTDSQLAGFMRNAAG  955


 Score =  257 bits (657),  Expect = 9e-66, Method: Compositional matrix adjust.
 Identities = 189/374 (51%), Positives = 222/374 (60%), Gaps = 62/374 (16%)

Query  215   QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFG---------------  259
               G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFG               
Sbjct  960   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  1019

Query  260   -------------------------------NTGNGNIGF----------GLTGDNQQGF  278
                                            N GNGNIGF          GLTGDNQ GF
Sbjct  1020  NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGF  1079

Query  279   GGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIAN  338
             G  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN G ANTG FN G  N
Sbjct  1080  GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNVGNANTGLFNTGNVN  1138

Query  339   TGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYS  398
             TGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN G++NTG   SG+YS
Sbjct  1139  TGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYS  1198

Query  399   NGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGP  458
             NG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP I L +N+ G  VGP
Sbjct  1199  NGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGG-VGP  1257

Query  459   INVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---QVINVGSISIPASPL  515
             I VP IT+P I L +N+ G  VGPI +P IT+  I L L+A      I V  I+IP  PL
Sbjct  1258  IVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1316

Query  516   AIGLFGVNPTVGSI  529
             ++   G N  + S+
Sbjct  1317  SLNALGGNFRLTSL  1330


 Score =  194 bits (494),  Expect = 8e-47, Method: Compositional matrix adjust.
 Identities = 196/537 (37%), Positives = 265/537 (50%), Gaps = 108/537 (20%)

Query  920   QVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTG  979
              +  G  NSG G +G  N G  N+G  N G  N G+GN G+ N GLGN GN N G  NTG
Sbjct  214   NLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTG  273

Query  980   N-----------------------------------------------------VNTGIG  986
             N                                                      NTGIG
Sbjct  274   NGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSATSYNTGIG  333

Query  987   NAGSYNTG--------------------SYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG  1026
             N G  NTG                    S+N G  NTGD N G++NTG+ N G+LNTG G
Sbjct  334   NTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVG  393

Query  1027  NIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITI  1086
             N G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITI
Sbjct  394   NTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI  453

Query  1087  PGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG  1144
             P I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G 
Sbjct  454   PEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGA  513

Query  1145  -VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPI  1201
              VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP + +
Sbjct  514   LVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITV  573

Query  1202  SRIPLTIN----IRIPVNITLNELP-----FNVAGIFTGYIGPIPLSTFVLGVTLAG---  1249
               I L ++    +  P+N+    +P      N  G   G I   P++   +G+ L+    
Sbjct  574   PAIGLGVSSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQV  633

Query  1250  ---GTLESGIQGFSVNPFGLN----------IPLSGATNAV-TIPGFAINPFGLNVPLSG  1295
                G++       ++  FG+N          I +   T A+  IP F        V +SG
Sbjct  634   INVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPAIPAIPPFFPGFPPDYVTVSG  693

Query  1296  GTSPVTIP--GFAINPFGLNVPLSGGTSPVTI--PGFTIPGSPLNLTANGGLGPINI  1348
                P+T    G+++    L + + GG  P T+   G+++P  PL +   GGLGP  +
Sbjct  694   QIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  750


 Score = 67.4 bits (163),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 66/190 (35%), Positives = 79/190 (42%), Gaps = 83/190 (43%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRI  1212
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N   
Sbjct  1217  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNAL-  1275

Query  1213  PVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSG  1272
                               G +GPI +                                  
Sbjct  1276  ------------------GGVGPIVVPD--------------------------------  1285

Query  1273  ATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPG  1332
                 +TIPG    P  LN    GG  P+                        +P  TIPG
Sbjct  1286  ----ITIPGI---PLSLNA--LGGVGPI-----------------------VVPDITIPG  1313

Query  1333  SPLNLTANGG  1342
              PL+L A GG
Sbjct  1314  IPLSLNALGG  1323


 Score = 47.0 bits (110),  Expect = 0.030, Method: Compositional matrix adjust.
 Identities = 29/84 (35%), Positives = 46/84 (55%), Gaps = 0/84 (0%)

Query  1266  LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTI  1325
             L++ ++G    + +P   I    L++   GG  P+ +P   I    L++   GG  P+ +
Sbjct  1224  LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVV  1283

Query  1326  PGFTIPGSPLNLTANGGLGPINIP  1349
             P  TIPG PL+L A GG+GPI +P
Sbjct  1284  PDITIPGIPLSLNALGGVGPIVVP  1307


>gi|308402956|ref|ZP_07493652.2| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|308365845|gb|EFP54696.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=745

 Score = 1200 bits (3104),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 734/734 (100%), Positives = 734/734 (100%), Gaps = 0/734 (0%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12   MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV
Sbjct  432  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  491

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  540
            GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT
Sbjct  492  GPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGT  551

Query  541  PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  600
            PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS
Sbjct  552  PEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYS  611

Query  601  LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  660
            LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV
Sbjct  612  LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  671

Query  661  GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  720
            GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG
Sbjct  672  GGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGG  731

Query  721  TSGFGNVGSGGSGF  734
            TSGFGNVGSGGSGF
Sbjct  732  TSGFGNVGSGGSGF  745


 Score =  343 bits (881),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 273/567 (49%), Positives = 335/567 (60%), Gaps = 62/567 (10%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  216   SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  274

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  275   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  334

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  335   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  394

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  395   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  454

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGV  1145
              I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A    
Sbjct  455   EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---  511

Query  1146  GPIVVPDITIPGIPLSLN------ALGGVGP-IVVPDITIPGIPL-----------SLNA  1187
               I V  I+IP  PL++        +G +GP  +   +  P IP             +  
Sbjct  512   QVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTV  571

Query  1188  LGGVGPITVP--GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGV  1245
              G +GPIT    G  +  IPL I++                G FT +     L    LG+
Sbjct  572   SGQIGPITFLSGGYSLPAIPLGIDVG------------GGLGPFTVFPDGYSLPAIPLGI  619

Query  1246  TLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI--P  1303
              + G     G+  F+V P G ++P         IP        L + + GG  P T+   
Sbjct  620   DVGG-----GLGPFTVFPDGYSLP--------AIP--------LGIDVGGGLGPFTVFPD  658

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  659   GYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  718

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGL  1390
             TPSSGFFNSG G  SGFGNVG G SG 
Sbjct  719   TPSSGFFNSGTGGTSGFGNVGSGGSGF  745


 Score = 53.5 bits (127),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 60/156 (39%), Positives = 77/156 (50%), Gaps = 18/156 (11%)

Query  720  GTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLA  775
            G  GFGN G+G  GF     N    G  N G    G+ N G    G+ NT T    +G +
Sbjct  265  GNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNS  324

Query  776  TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  835
             +++++G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N 
Sbjct  325  GTSYNTGIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNT  375

Query  836  GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  871
            GS N      GF N G+ N G GN G+ N G  N+G
Sbjct  376  GSSNT-----GFFNPGNLNTGVGNTGNVNTGGFNSG  406


>gi|306797742|ref|ZP_07436044.1| hypothetical protein TMFG_01000 [Mycobacterium tuberculosis SUMu006]
 gi|308341936|gb|EFP30787.1| hypothetical protein TMFG_01000 [Mycobacterium tuberculosis SUMu006]
Length=703

 Score = 1151 bits (2978),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 670/743 (91%), Positives = 680/743 (92%), Gaps = 46/743 (6%)

Query  607   GIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGP  666
             GIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGP
Sbjct  1     GIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGP  60

Query  667   LTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGN  726
             LTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGN
Sbjct  61    LTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGN  120

Query  727   VGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNT  786
             VGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNT
Sbjct  121   VGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNT  180

Query  787   DSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFG  846
             DSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFG
Sbjct  181   DSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFG  240

Query  847   FGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNT  906
             FGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNT
Sbjct  241   FGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNT  300

Query  907   GTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLG  966
             GTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLG
Sbjct  301   GTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLG  360

Query  967   NVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG  1026
             NVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG
Sbjct  361   NVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG  420

Query  1027  NIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITI  1086
             NIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITI
Sbjct  421   NIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITI  480

Query  1087  PGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG  1146
             PGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG
Sbjct  481   PGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG  540

Query  1147  PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPL  1206
             PI VP + I  IPL++                                            
Sbjct  541   PITVPGVPISRIPLTI--------------------------------------------  556

Query  1207  TINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGL  1266
               NIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGL
Sbjct  557   --NIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGL  614

Query  1267  NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIP  1326
             NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGL+VPLSGGT+ VTIP
Sbjct  615   NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIP  674

Query  1327  GFTIPGSPLNLTANGGLGPINIP  1349
             GF I    L++  +GG   + IP
Sbjct  675   GFAINPFGLDVPLSGGTNAVTIP  697


 Score =  286 bits (731),  Expect = 3e-74, Method: Compositional matrix adjust.
 Identities = 224/491 (46%), Positives = 290/491 (60%), Gaps = 38/491 (7%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  243  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  302

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  303  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  361

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  362  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  421

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  422  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  481

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVI  503
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A    
Sbjct  482  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALG--  537

Query  504  NVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIP-AIPPFFPGFPPDYVTVSG  562
             VG I++P  P++     +N  +    P +I++     E+P  +   F G+         
Sbjct  538  GVGPITVPGVPISRIPLTINIRI----PVNITLN----ELPFNVAGIFTGY---------  580

Query  563  QIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPD  622
             IGPI        L    LG+ + GG     +   G+S+    L I + G     T+   
Sbjct  581  -IGPI-------PLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--P  628

Query  623  GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGID  682
            G+++    L + + GG  P T+   G+++    L + + G    +T P   I    L + 
Sbjct  629  GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLDVP  686

Query  683  VSGSLGPINIP  693
            +SG    + IP
Sbjct  687  LSGGTNAVTIP  697


 Score =  123 bits (308),  Expect = 3e-25, Method: Compositional matrix adjust.
 Identities = 92/180 (52%), Positives = 110/180 (62%), Gaps = 5/180 (2%)

Query  1281  GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLT  1338
             G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL + 
Sbjct  17    GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGID  76

Query  1339  ANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNAL  1398
              +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N  
Sbjct  77    VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  135

Query  1399  QGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  136   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  193


 Score = 46.2 bits (108),  Expect = 0.046, Method: Compositional matrix adjust.
 Identities = 56/150 (38%), Positives = 73/150 (49%), Gaps = 18/150 (12%)

Query  260  NTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNT  319
            N G+G  GF     N    G  N G    G+ N G    G+ NT T    +G + +++++
Sbjct  120  NVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLATSAFHS  175

Query  320  GIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-  369
            G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N GS N  
Sbjct  176  GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  235

Query  370  ----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
                GF N G+ N G GN G+ N G  N+G
Sbjct  236  NGSFGFGNIGSNNFGFGNVGSNNLGFANTG  265


 Score = 40.8 bits (94),  Expect = 2.2, Method: Compositional matrix adjust.
 Identities = 52/178 (30%), Positives = 69/178 (39%), Gaps = 67/178 (37%)

Query  1176  ITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGP  1235
             ++IP IPLS+   GG+GPI VP + I  IPL+          LN L         G +GP
Sbjct  455   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLS----------LNAL---------GGVGP  495

Query  1236  IPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSG  1295
             I +                                      +TIPG    P  LN    G
Sbjct  496   IVVPD------------------------------------ITIPGI---PLSLNA--LG  514

Query  1296  GTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINIT  1353
             G  P+ +P   I    L++   GG  P+T+PG  I   PL +        I IP+NIT
Sbjct  515   GVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNIT  565


>gi|340626927|ref|YP_004745379.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005117|emb|CCC44266.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
Length=2222

 Score = 1150 bits (2974),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 721/956 (76%), Positives = 773/956 (81%), Gaps = 59/956 (6%)

Query  413   FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  468
             F     +PA  L ++  G +GP T+      +P I LGI+  G L GP  V P    +PA
Sbjct  861   FPDGYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGGL-GPFTVFPDGYALPA  919

Query  469   IGLGINSTGALVGPINI-------PPITLN-SIGLELSAFQVINVGSISIPASPLAIGLF  520
             I LGI+  G L GP  +       P I L   +G  L  F V   G  ++PA PL I + 
Sbjct  920   IPLGIDVGGGL-GPFTVFPDGYALPAIPLGIDVGGGLGPFTVFPDG-YALPAIPLGIDVG  977

Query  521   GVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIP  580
             G        G G  ++      +PAIP          + V G +GP T    GY+LPAIP
Sbjct  978   G--------GLGPFTVFPDGYALPAIP--------LGIDVGGGLGPFTVFPDGYALPAIP  1021

Query  581   LGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG  640
             LGID GGGLGPF VFPDGY+LPAIPLGIDVGGGLGPFTVFPDGY+LPAIPLGIDVGGGLG
Sbjct  1022  LGIDAGGGLGPFPVFPDGYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGGLG  1081

Query  641   PFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTP  700
             PFTVFPDGY+LPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTP
Sbjct  1082  PFTVFPDGYALPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTP  1141

Query  701   GFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFG  760
             GFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFG
Sbjct  1142  GFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFG  1201

Query  761   NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANL  820
             NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANL
Sbjct  1202  NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANL  1261

Query  821   GDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHN  880
             GDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHN
Sbjct  1262  GDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHN  1321

Query  881   IGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGN  940
             IGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGN
Sbjct  1322  IGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGN  1381

Query  941   GNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGD  1000
             GNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGD
Sbjct  1382  GNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGD  1441

Query  1001  TNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDT  1060
             TNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDT
Sbjct  1442  TNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDT  1501

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGG+GPIVVPDITIPGIPLSLNALG
Sbjct  1502  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGIGPIVVPDITIPGIPLSLNALG  1561

Query  1121  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1180
             G+GPIVVPDITIPGIPLSLNALGG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG
Sbjct  1562  GIGPIVVPDITIPGIPLSLNALGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1621

Query  1181  IPLSLNALGGVGPITVPGVPISRIPLTIN-------IRIPVNITLNELPFNVAGIFTGYI  1233
             IPLSLNALGGVGPI VP + I  IPL++N       I +P +IT+  +P ++  +  G +
Sbjct  1622  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP-DITIPGIPLSLNAL--GGV  1678

Query  1234  GPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPL  1293
             GPI     V  +T+ G  L       S+N  G   P+      +TIPG    P  LN   
Sbjct  1679  GPI----VVPDITIPGIPL-------SLNALGGVGPI--VVPDITIPGI---PLSLNA--  1720

Query  1294  SGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
              GG  P+ +P   I    L++   GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  1721  LGGIGPIVVPDITIPGIPLSLNALGGIGPIVVPDITIPGIPLSLNALGGVGPITVP  1776


 Score =  865 bits (2234),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/700 (81%), Positives = 603/700 (87%), Gaps = 29/700 (4%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAA APYLGWLA AAAQAQRSATQAAALV EFEAVRAAMVQPALVAANRSDLVSL
Sbjct  61   SSAAMAAAAAPYLGWLATAAAQAQRSATQAAALVTEFEAVRAAMVQPALVAANRSDLVSL  120

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSN FGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLT LPA
Sbjct  121  VFSNLFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTGLPA  180

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVV AAITSSKGVLANLSLGLANSGFG MGAANLGILNLG LNPGGNNFGLGN
Sbjct  181  QLAAAPAAVVNAAITSSKGVLANLSLGLANSGFGHMGAANLGILNLGGLNPGGNNFGLGN  240

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSG SYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  301  GNTGTGNFGIGNSGASYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGS+GPITIPSITIPEIGLGINSSGALVGPI+VPPITVPAIGLG++S+GALV
Sbjct  421  AAGLDLNGLGSIGPITIPSITIPEIGLGINSSGALVGPIDVPPITVPAIGLGVSSSGALV  480

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPL-AIGLFGVNPTVGSIGPGSISIQLG  539
            GPI++PPIT+ +IGL +S+   + VG IS+P   + AIGL GV+ +   +GP    I + 
Sbjct  481  GPISVPPITVPAIGLGVSSSGAL-VGPISVPPITVPAIGL-GVSSSGALVGP----ISVP  534

Query  540  TPEIPAIPPFFPGFPPDYVTVSGQ-IGPITFLSGGYSLPAIPLGIDVGGGL-GPFTVFPD  597
               +PAI     G     V+ SG  +GPI+      ++PAI LG+   G L GP +V P 
Sbjct  535  PITVPAI-----GL---GVSSSGALVGPISVPP--ITVPAIGLGVSSSGALVGPISVPP-  583

Query  598  GYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPAIP  655
              ++PAI LGI+  G L GP  V P   ++PAI LG+   G L GP  V P   ++PAI 
Sbjct  584  -ITVPAIGLGINSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPP--ITVPAIG  638

Query  656  LGIDVGGA-IGPLTTPPITIPSIPLGIDVSGSL-GPINIP  693
            LG+   GA +GP+  PPIT+P+I LGI+ SG+L GPIN+P
Sbjct  639  LGVSSSGALVGPINVPPITVPAIGLGINSSGALVGPINVP  678


 Score =  468 bits (1204),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 263/289 (92%), Positives = 275/289 (96%), Gaps = 0/289 (0%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1120
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG
Sbjct  1640  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG  1699

Query  1121  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1180
             GVGPIVVPDITIPGIPLSLNALGG+GPIVVPDITIPGIPLSLNALGG+GPIVVPDITIPG
Sbjct  1700  GVGPIVVPDITIPGIPLSLNALGGIGPIVVPDITIPGIPLSLNALGGIGPIVVPDITIPG  1759

Query  1181  IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST  1240
             IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST
Sbjct  1760  IPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLST  1819

Query  1241  FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPV  1300
             FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGL+VPLSGGTSPV
Sbjct  1820  FVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLDVPLSGGTSPV  1879

Query  1301  TIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             TIPGFAINPFGL+VPLSGGTSPVTIPGF I    L++  +GG  P+ IP
Sbjct  1880  TIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIP  1928


 Score =  391 bits (1005),  Expect = 5e-106, Method: Compositional matrix adjust.
 Identities = 269/470 (58%), Positives = 302/470 (65%), Gaps = 73/470 (15%)

Query  1061  LSIPAIPLSVEVNGGIGPIVVPDITIPGIP----------LSLNAL---------GGVGP  1101
             ++IP IPLS+   GG+GPI VP + I  IP          ++LN L         G +GP
Sbjct  1755  ITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGP  1814

Query  1102  IVVPD------------------------------------ITIPGI---PLSLNA--LG  1120
             I +                                      +TIPG    P  L+    G
Sbjct  1815  IPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLDVPLSG  1874

Query  1121  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  1180
             G  P+ +P   I    L +   GG  P+ +P   I    L +   GG  P+ +P   I  
Sbjct  1875  GTSPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINP  1934

Query  1181  IPLSLNALGGVGPITVPGVPISRIPLTINIR---IPVNI---TLNELPFNVAGIFTGYIG  1234
               L +   GG  P+T+PG  I+   L + +     PV I    +N    NV    +G   
Sbjct  1935  FGLDVPLSGGTSPVTIPGFAINPFGLDVPLSGGTSPVTIPGFAINPFGLNVP--LSGGTS  1992

Query  1235  PIPLSTFV-----LGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGL  1289
             P+ +  F      L V L+GGT    I GF++NPFGLN+PLSG TNAVTIPGFAINPFGL
Sbjct  1993  PVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGLNVPLSGGTNAVTIPGFAINPFGL  2052

Query  1290  NVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             NVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP
Sbjct  2053  NVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  2112

Query  1350  INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVG  1409
             INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVG
Sbjct  2113  INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVG  2172

Query  1410  QLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
             QLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
Sbjct  2173  QLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  2222


 Score =  332 bits (850),  Expect = 4e-88, Method: Compositional matrix adjust.
 Identities = 253/514 (50%), Positives = 319/514 (63%), Gaps = 29/514 (5%)

Query  849   NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  908
             ++G  N GFG++G+ NLG  N G GL    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  205   SLGLANSGFGHMGAANLGILNLG-GLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263

Query  909   GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  967
             GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGASYNTGIGN  323

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  1087
              G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G IGPI +P ITIP
Sbjct  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSIGPITIPSITIP  443

Query  1088  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-  1144
              I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  
Sbjct  444   EIGLGINSSGALVGPIDVPPITVPAIGLGVSSSGALVGPISVPPITVPAIGLGVSSSGAL  503

Query  1145  VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPIS  1202
             VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI+VP     
Sbjct  504   VGPISVPPITVPAIGLGVSSSGALVGPISVPPITVPAIGLGVSSSGALVGPISVP-----  558

Query  1203  RIPLTINIRIPVNITLNELPFNVAGIFTGYIG--PIPLSTFVLGVTLAGGTL-ESGIQGF  1259
                       P+ +    L  + +G   G I   PI +    LG+  +G  +    +   
Sbjct  559   ----------PITVPAIGLGVSSSGALVGPISVPPITVPAIGLGINSSGALVGPINVPPI  608

Query  1260  SVNPFGLNIPLSGA-TNAVTIPGFAINPFGLNVPLSGG-TSPVTIPGFAINPFGLNVPLS  1317
             +V   GL +  SGA    + +P   +   GL V  SG    P+ +P   +   GL +  S
Sbjct  609   TVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGINSS  668

Query  1318  GG-TSPVTIPGFTIPGSPLNLTANGGL-GPINIP  1349
             G    P+ +P  T+P   L + + G L GPINIP
Sbjct  669   GALVGPINVPPITVPAIGLGINSTGALVGPINIP  702


 Score =  197 bits (502),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 196/475 (42%), Positives = 255/475 (54%), Gaps = 42/475 (8%)

Query  1020  DLNTGWGNIGDLNTGALISGSYSNGILWRG-DYQGLIG----YSDTLSIPAIPLSVEVNG  1074
             D  T  G IG +     +SG YS   +  G D  G +G    + D  ++PAIPL ++V G
Sbjct  772   DYVTVSGQIGPI---TFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGG  828

Query  1075  GIGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD  1129
             G+GP  V PD   +P IPL ++  GG+GP  V PD   +P IPL ++  GG+GP  V PD
Sbjct  829   GLGPFTVFPDGYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGGLGPFTVFPD  888

Query  1130  -ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLS  1184
                +P IPL ++  GG+GP  V PD   +P IPL ++  GG+GP  V PD   +P IPL 
Sbjct  889   GYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLG  948

Query  1185  LNALGGVGPITV--PGVPISRIPLTINI--------RIPVNITLNELPFNV-----AGIF  1229
             ++  GG+GP TV   G  +  IPL I++          P    L  +P  +      G F
Sbjct  949   IDVGGGLGPFTVFPDGYALPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGGLGPF  1008

Query  1230  TGYIGPIPLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI--PGFAIN  1285
             T +     L    LG+   GG     +   G+++    L I + G     T+   G+A+ 
Sbjct  1009  TVFPDGYALPAIPLGIDAGGGLGPFPVFPDGYALPAIPLGIDVGGGLGPFTVFPDGYALP  1068

Query  1286  PFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGL  1343
                L + + GG  P T+   G+A+    L + + G   P+T P  TIP  PL +  +G L
Sbjct  1069  AIPLGIDVGGGLGPFTVFPDGYALPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSL  1128

Query  1344  GPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVS  1403
             GPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N    G S
Sbjct  1129  GPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNS  1185

Query  1404  GIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  1186  GFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  1240


 Score =  170 bits (430),  Expect = 2e-39, Method: Compositional matrix adjust.
 Identities = 225/671 (34%), Positives = 310/671 (47%), Gaps = 119/671 (17%)

Query  764   SGLYNTSTLGLATSAF-HSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGD  822
              G+    +LGLA S F H G  N                + N G  N G  N G  N+G 
Sbjct  198   KGVLANLSLGLANSGFGHMGAANLG--------------ILNLGGLNPGGNNFGLGNVGS  243

Query  823   YNVGSGNVGSYNFGSGNIGNGSFGFG----------------------NIGSNNFGFGNV  860
              NVG GN G+ N G GN GNG+ GFG                      N G+ N G GN 
Sbjct  244   NNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNT  303

Query  861   GSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQ  920
             G+ N G  N+G     A +N G GN G  N GF N G  N G GNTG  N          
Sbjct  304   GTGNFGIGNSG-----ASYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNT---------  349

Query  921   VGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGN  980
                G+ N GS N G FN+G+ N GFFN GN N G+GN+GN NTG  N GN + G F  G+
Sbjct  350   ---GSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGD  406

Query  981   VNTGIGNAGSYNTGSYNAGDTNTGDLNP---GNANTGYLNLGDLNTGWGNIGDLNTGALI  1037
                 IG +G+    +        G + P    +     + LG +N+    +G ++   + 
Sbjct  407   YQGLIGFSGTLTIPAAGLDLNGLGSIGPITIPSITIPEIGLG-INSSGALVGPIDVPPIT  465

Query  1038  SGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGG-IGPIVVPDITIPGIPLSLNAL  1096
               +   G+   G   G I     +++PAI L V  +G  +GPI VP IT+P I L +++ 
Sbjct  466   VPAIGLGVSSSGALVGPISVPP-ITVPAIGLGVSSSGALVGPISVPPITVPAIGLGVSSS  524

Query  1097  GG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDI  1153
             G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  VGPI VP I
Sbjct  525   GALVGPISVPPITVPAIGLGVSSSGALVGPISVPPITVPAIGLGVSSSGALVGPISVPPI  584

Query  1154  TIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTIN--  1209
             T+P I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP + +  I L ++  
Sbjct  585   TVPAIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSS  644

Query  1210  --IRIPVNITLNELP-----FNVAGIFTGYIG--PIPLSTFVLGVTLAGGTL-ESGIQGF  1259
               +  P+N+    +P      N +G   G I   PI +    LG+   G  +    I   
Sbjct  645   GALVGPINVPPITVPAIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPI  704

Query  1260  SVNPFGLNIPLSGATNA--VTIPG--FAINPFGLN-------------------------  1290
             ++N  GL +      N   ++IP    AI  FG+N                         
Sbjct  705   TLNSIGLELSAFQVINVGLISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPELPAIPP  764

Query  1291  ---------VPLSGGTSPVTIP--GFAINPFGLNVPLSGGTSPVTI--PGFTIPGSPLNL  1337
                      V +SG   P+T    G+++    L + + GG  P T+   G+ +P  PL +
Sbjct  765   FFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYALPAIPLGI  824

Query  1338  TANGGLGPINI  1348
                GGLGP  +
Sbjct  825   DVGGGLGPFTV  835


 Score =  148 bits (373),  Expect = 8e-33, Method: Compositional matrix adjust.
 Identities = 143/381 (38%), Positives = 192/381 (51%), Gaps = 30/381 (7%)

Query  423   GLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGP  482
             GLD+   G   P+TIP   I   GL +  SG    P+ +P   +   GL +  +G    P
Sbjct  1867  GLDVPLSGGTSPVTIPGFAINPFGLDVPLSGG-TSPVTIPGFAINPFGLDVPLSGG-TSP  1924

Query  483   INIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPE  542
             + IP   +N  GL++          +S   SP+ I  F +NP         + + L    
Sbjct  1925  VTIPGFAINPFGLDVP---------LSGGTSPVTIPGFAINPF-------GLDVPLSGGT  1968

Query  543   IPAIPPFFPGFPPDY-VTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSL  601
              P   P F   P    V +SG   P+T    G+++    L + + GG    T+   G+++
Sbjct  1969  SPVTIPGFAINPFGLNVPLSGGTSPVTIP--GFAINPFGLNVPLSGGTNAVTI--PGFAI  2024

Query  602   PAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVG  661
                 L + + GG    T+   G+++    L + + GG  P T+   G+++    L + + 
Sbjct  2025  NPFGLNVPLSGGTNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLS  2080

Query  662   GAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGT  721
             G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  
Sbjct  2081  GGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSA  2140

Query  722   SGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSA  778
             SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G  T+A
Sbjct  2141  SGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAA  2200

Query  779   FHSGVGNTDSQLAGFMRNAAG  799
             F+SGV N    L GF    AG
Sbjct  2201  FNSGVNNIGQMLLGFFSPGAG  2221


 Score = 55.1 bits (131),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 60/156 (39%), Positives = 77/156 (50%), Gaps = 18/156 (11%)

Query  720  GTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLA  775
            G  GFGN G+G  GF     N    G  N G    G+ N G    G+ NT T    +G +
Sbjct  254  GNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNS  313

Query  776  TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  835
             +++++G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N 
Sbjct  314  GASYNTGIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNT  364

Query  836  GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  871
            GS N      GF N G+ N G GN G+ N G  N+G
Sbjct  365  GSSNT-----GFFNPGNLNTGVGNTGNVNTGGFNSG  395


>gi|913250|gb|AAC60492.1| orf 5' of katG [Mycobacterium tuberculosis]
 gi|1092645|prf||2024332A katG protein
Length=693

 Score = 1079 bits (2791),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 620/623 (99%), Positives = 621/623 (99%), Gaps = 0/623 (0%)

Query  316  SYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPG  375
            SYNTGIGNTGQANTGFFNAGIANTGIGNTG YNTGSFNLGSFNTGDFNTGSSNTGFFNPG
Sbjct  1    SYNTGIGNTGQANTGFFNAGIANTGIGNTGTYNTGSFNLGSFNTGDFNTGSSNTGFFNPG  60

Query  376  NLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPI  435
            NLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPI
Sbjct  61   NLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPI  120

Query  436  TIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL  495
            TIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL
Sbjct  121  TIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL  180

Query  496  ELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPP  555
            ELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPP
Sbjct  181  ELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPP  240

Query  556  DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG  615
            DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG
Sbjct  241  DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLG  300

Query  616  PFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP  675
            PFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP
Sbjct  301  PFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP  360

Query  676  SIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFW  735
            SIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGT+GFGNVGSGGSGFW
Sbjct  361  SIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTTGFGNVGSGGSGFW  420

Query  736  NIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMR  795
            NIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMR
Sbjct  421  NIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMR  480

Query  796  NAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNF  855
            NAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNF
Sbjct  481  NAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNF  540

Query  856  GFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGL  915
            GFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGL
Sbjct  541  GFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGL  600

Query  916  TGDNQVGFGALNSGSGNIGFFNS  938
            T DNQVGFGALNSGSGNIGFFNS
Sbjct  601  TADNQVGFGALNSGSGNIGFFNS  623


 Score =  293 bits (751),  Expect = 1e-76, Method: Compositional matrix adjust.
 Identities = 237/522 (46%), Positives = 296/522 (57%), Gaps = 63/522 (12%)

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTG+GN G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+
Sbjct  2     YNTGIGNTGQANTGFFNAGIANTGIGNTGTYNTGSFNLGSFNTGDFNTGSSNTGFFNPGN  61

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIV  1080
             LNTG GN G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI 
Sbjct  62    LNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPIT  121

Query  1081  VPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLS  1138
             +P ITIP I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L 
Sbjct  122   IPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLE  181

Query  1139  LNALGGVGPIVVPDITIPGIPLSLN------ALGGVGP-IVVPDITIPGIPL--------  1183
             L+A      I V  I+IP  PL++        +G +GP  +   +  P IP         
Sbjct  182   LSAF---QVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGF  238

Query  1184  ---SLNALGGVGPITVP--GVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPL  1238
                 +   G +GPIT    G  +  IPL I++   +            G FT +     L
Sbjct  239   PPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGL------------GPFTVFPDGYSL  286

Query  1239  STFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTS  1298
                 LG+ + G     G+  F+V P G ++P         IP        L + + GG  
Sbjct  287   PAIPLGIDVGG-----GLGPFTVFPDGYSLP--------AIP--------LGIDVGGGLG  325

Query  1299  PVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAP  1356
             P T+   G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   P
Sbjct  326   PFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTP  385

Query  1357  GFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVA  1416
             GFGNSTTTPSSGFFNSG G  +GFGNVG G SG WN   N    G SG  NVG L SG+ 
Sbjct  386   GFGNSTTTPSSGFFNSGTGGTTGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGIL  442

Query  1417  NLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  443   NFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  484


 Score = 87.4 bits (215),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 55/89 (62%), Positives = 61/89 (69%), Gaps = 1/89 (1%)

Query  206  LGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  264
            +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  535  IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  594

Query  265  NIGFGLTGDNQQGFGGWNSGTGNIGLFNS  293
            NIG GLT DNQ GFG  NSG+GNIG FNS
Sbjct  595  NIGIGLTADNQVGFGALNSGSGNIGFFNS  623


 Score = 78.6 bits (192),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 69/141 (49%), Positives = 76/141 (54%), Gaps = 8/141 (5%)

Query  215  QMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDN  274
              G AN G LNLG+ N G  N G GNVGS N G GN GNG+ GFGN G+ N GFG  G N
Sbjct  489  NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  548

Query  275  QQGFG----GWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTG  330
              GF     G      NIG  N G  N G  N G GN G GN+GT  N GIG T     G
Sbjct  549  NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG-NIGIGLTADNQVG  607

Query  331  FFNAGIANTGIGNTGNYNTGS  351
            F   G  N+G GN G +N+ S
Sbjct  608  F---GALNSGSGNIGFFNSSS  625


 Score = 65.5 bits (158),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 86/235 (37%), Positives = 111/235 (48%), Gaps = 21/235 (8%)

Query  849   NIGSNNFGFGNVGSN--NLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNT  906
             N+GS   GF N+  N  N GF N GP LT  + N  FGN     Y  + +G     F ++
Sbjct  411   NVGSGGSGFWNIAGNLGNSGFLNVGP-LTSGILN--FGNTVSGLYNTSTLGLATSAF-HS  466

Query  907   GTGNIGIGLTGDNQVGFGALNSGSG---NIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNT  963
             G GN       D+Q+     N+  G   N GF N G  N+G  N G+ NVG GN G+YN 
Sbjct  467   GVGNT------DSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  520

Query  964   GLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGD------TNTGDLNPGNANTGYLN  1017
             G GN+GN + G  N G+ N G GN GS N G  N G        N G  N G  N G+ N
Sbjct  521   GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFAN  580

Query  1018  LGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEV  1072
             +G+ N G+GN G  N G  ++     G        G IG+ ++ S  A   S   
Sbjct  581   IGNGNIGFGNTGTGNIGIGLTADNQVGFGALNSGSGNIGFFNSSSTQATETSASA  635


 Score = 42.7 bits (99),  Expect = 0.58, Method: Compositional matrix adjust.
 Identities = 58/155 (38%), Positives = 76/155 (50%), Gaps = 23/155 (14%)

Query  255  NIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSG  314
            N+G G +G  NI   L      GF   N G    G+ N G    G+ NT T    +G + 
Sbjct  411  NVGSGGSGFWNIAGNL---GNSGF--LNVGPLTSGILNFGNTVSGLYNTST----LGLAT  461

Query  315  TSYNTGIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTG  365
            +++++G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N G
Sbjct  462  SAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFG  521

Query  366  SSNT-----GFFNPGNLNTGVGNTGNVNTGGFNSG  395
            S N      GF N G+ N G GN G+ N G  N+G
Sbjct  522  SGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  556


 Score = 42.0 bits (97),  Expect = 0.96, Method: Compositional matrix adjust.
 Identities = 35/72 (49%), Positives = 41/72 (57%), Gaps = 5/72 (6%)

Query  207  GLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNI  266
            G+AN+G G  G  N G  NLGS N G  +F   N GS+N G  N GN N G GNTGN N 
Sbjct  20   GIANTGIGNTGTYNTGSFNLGSFNTG--DF---NTGSSNTGFFNPGNLNTGVGNTGNVNT  74

Query  267  GFGLTGDNQQGF  278
            G   +G+   GF
Sbjct  75   GGFNSGNYSNGF  86


 Score = 40.8 bits (94),  Expect = 1.8, Method: Compositional matrix adjust.
 Identities = 45/99 (46%), Positives = 53/99 (54%), Gaps = 7/99 (7%)

Query  207  GLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNI  266
            G AN+GF   G AN GI N G+ N G  N     +GS N G  NTG+ N GF N GN N 
Sbjct  10   GQANTGFFNAGIANTGIGNTGTYNTGSFN-----LGSFNTGDFNTGSSNTGFFNPGNLNT  64

Query  267  GFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGT  305
            G G TG+     GG+NSG  + G F  G     IG +GT
Sbjct  65   GVGNTGNVNT--GGFNSGNYSNGFFWRGDYQGLIGFSGT  101


>gi|308373272|ref|ZP_07431668.2| hypothetical protein TMEG_01810 [Mycobacterium tuberculosis SUMu005]
 gi|308338231|gb|EFP27082.1| hypothetical protein TMEG_01810 [Mycobacterium tuberculosis SUMu005]
Length=587

 Score = 1031 bits (2665),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 585/587 (99%), Positives = 587/587 (100%), Gaps = 0/587 (0%)

Query  558   VTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF  617
             +TVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF
Sbjct  1     MTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF  60

Query  618   TVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSI  677
             TVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+I
Sbjct  61    TVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAI  120

Query  678   PLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNI  737
             PLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNI
Sbjct  121   PLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNI  180

Query  738   AGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNA  797
             AGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNA
Sbjct  181   AGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNA  240

Query  798   AGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGF  857
             AGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGF
Sbjct  241   AGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGF  300

Query  858   GNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTG  917
             GNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTG
Sbjct  301   GNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTG  360

Query  918   DNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFN  977
             DNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFN
Sbjct  361   DNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFN  420

Query  978   TGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALI  1037
             TGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALI
Sbjct  421   TGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALI  480

Query  1038  SGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALG  1097
             SGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALG
Sbjct  481   SGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALG  540

Query  1098  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG  1144
             GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG
Sbjct  541   GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG  587


 Score =  279 bits (713),  Expect = 3e-72, Method: Compositional matrix adjust.
 Identities = 180/297 (61%), Positives = 212/297 (72%), Gaps = 4/297 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  292  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  351

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  352  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  410

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  411  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  470

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  471  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  530

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF  500
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A 
Sbjct  531  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNAL  585


 Score =  125 bits (314),  Expect = 6e-26, Method: Compositional matrix adjust.
 Identities = 108/242 (45%), Positives = 134/242 (56%), Gaps = 16/242 (6%)

Query  1230  TGYIGPI-------PLSTFVLGVTLAGGTLESGI--QGFSVNPFGLNIPLSGATNAVTI-  1279
             +G IGPI        L    LG+ + GG     +   G+S+    L I + G     T+ 
Sbjct  4     SGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVF  63

Query  1280  -PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLN  1336
               G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL 
Sbjct  64    PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLG  123

Query  1337  LTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPN  1396
             +  +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N
Sbjct  124   IDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGN  183

Query  1397  ALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPG  1456
                 G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    
Sbjct  184   L---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNA  240

Query  1457  AG  1458
             AG
Sbjct  241   AG  242


 Score = 86.3 bits (212),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 61/144 (43%), Positives = 90/144 (63%), Gaps = 9/144 (6%)

Query  1070  VEVNGGIGPIVVPD--ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPI  1125
             + V+G IGPI       ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP 
Sbjct  1     MTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPF  60

Query  1126  VV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGI  1181
              V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP I
Sbjct  61    TVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAI  120

Query  1182  PLSLNALGGVGPITVPGVPISRIP  1205
             PL ++  G +GPI +P + I+  P
Sbjct  121   PLGIDVSGSLGPINIP-IEIAGTP  143


 Score = 46.6 bits (109),  Expect = 0.035, Method: Compositional matrix adjust.
 Identities = 30/80 (38%), Positives = 46/80 (58%), Gaps = 5/80 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  497   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  551

Query  1330  IPGSPLNLTANGGLGPINIP  1349
             IPG PL+L A GG+GPI +P
Sbjct  552   IPGIPLSLNALGGVGPIVVP  571


 Score = 44.7 bits (104),  Expect = 0.12, Method: Compositional matrix adjust.
 Identities = 52/131 (40%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG  N G  NT +G +    +G + +++++G+GNT     GF       
Sbjct  186  NSGFLNVGPLTSGILNFG--NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  243

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  244  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  303

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  304  GSNNLGFANTG  314


 Score = 38.9 bits (89),  Expect = 6.6, Method: Compositional matrix adjust.
 Identities = 51/139 (37%), Positives = 74/139 (54%), Gaps = 18/139 (12%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  468
             SG  ++PA  L ++  G +GP T+     ++P I LGI+  G L GP  V P   ++PA
Sbjct  13   LSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPA  71

Query  469  IGLGINSTGALVGPINIPP--ITLNSIGLELS---AFQVINVGSISIPASPLAIGLFGVN  523
            I LGI+  G L GP  + P   +L +I L +    A   +    I+IPA PL I +    
Sbjct  72   IPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDV----  126

Query  524  PTVGSIGPGSISIQL-GTP  541
               GS+GP +I I++ GTP
Sbjct  127  --SGSLGPINIPIEIAGTP  143


 Score = 38.5 bits (88),  Expect = 9.4, Method: Compositional matrix adjust.
 Identities = 25/77 (33%), Positives = 40/77 (52%), Gaps = 0/77 (0%)

Query  1266  LNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTI  1325
             L++ ++G    + +P   I    L++   GG  P+ +P   I    L++   GG  P+ +
Sbjct  511   LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVV  570

Query  1326  PGFTIPGSPLNLTANGG  1342
             P  TIPG PL+L A GG
Sbjct  571   PDITIPGIPLSLNALGG  587


>gi|294996832|ref|ZP_06802523.1| PPE family protein [Mycobacterium tuberculosis 210]
Length=670

 Score = 1026 bits (2653),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 577/579 (99%), Positives = 579/579 (100%), Gaps = 0/579 (0%)

Query  644   VFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFG  703
             +FPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFG
Sbjct  1     MFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFG  60

Query  704   NSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTV  763
             NSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTV
Sbjct  61    NSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTV  120

Query  764   SGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDY  823
             SGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDY
Sbjct  121   SGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDY  180

Query  824   NVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGF  883
             NVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGF
Sbjct  181   NVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGF  240

Query  884   GNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNI  943
             GNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNI
Sbjct  241   GNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNI  300

Query  944   GFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNT  1003
             GFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNT
Sbjct  301   GFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNT  360

Query  1004  GDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI  1063
             GDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI
Sbjct  361   GDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI  420

Query  1064  PAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG  1123
             PAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG
Sbjct  421   PAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVG  480

Query  1124  PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1183
             PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL
Sbjct  481   PIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL  540

Query  1184  SLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELP  1222
             SLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELP
Sbjct  541   SLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELP  579


 Score =  291 bits (745),  Expect = 6e-76, Method: Compositional matrix adjust.
 Identities = 209/411 (51%), Positives = 253/411 (62%), Gaps = 54/411 (13%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  206  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  265

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  266  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  324

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  325  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  384

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  385  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  444

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAF---  500
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P IT+  I L L+A    
Sbjct  445  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGGV  502

Query  501  QVINVGSISIPASPLAI-GLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVT  559
              I V  I+IP  PL++  L GV P V              P+I                
Sbjct  503  GPIVVPDITIPGIPLSLNALGGVGPIV-------------VPDI----------------  533

Query  560  VSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  610
                           ++P IPL ++  GG+GP TV   G  +  IPL I++
Sbjct  534  ---------------TIPGIPLSLNALGGVGPITV--PGVPISRIPLTINI  567


 Score =  120 bits (301),  Expect = 2e-24, Method: Compositional matrix adjust.
 Identities = 86/155 (56%), Positives = 98/155 (64%), Gaps = 3/155 (1%)

Query  1304  GFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTT  1363
             G+++    L + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTT
Sbjct  5     GYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTT  64

Query  1364  TPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVS  1423
             TPSSGFFNSG G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVS
Sbjct  65    TPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVS  121

Query  1424  GFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
             G  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  122   GLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  156


 Score = 95.1 bits (235),  Expect = 8e-17, Method: Compositional matrix adjust.
 Identities = 78/197 (40%), Positives = 96/197 (49%), Gaps = 60/197 (30%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRI  1212
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL+     
Sbjct  418   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS-----  472

Query  1213  PVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSG  1272
                  LN L         G +GPI +                                  
Sbjct  473   -----LNAL---------GGVGPIVVPD--------------------------------  486

Query  1273  ATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPG  1332
                 +TIPG    P  LN    GG  P+ +P   I    L++   GG  P+ +P  TIPG
Sbjct  487   ----ITIPGI---PLSLNA--LGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPG  537

Query  1333  SPLNLTANGGLGPINIP  1349
              PL+L A GG+GPI +P
Sbjct  538   IPLSLNALGGVGPITVP  554


 Score = 68.9 bits (167),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 55/174 (32%), Positives = 85/174 (49%), Gaps = 14/174 (8%)

Query  417  LTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINST  476
            +TIP   L LN LG VGPI +P ITIP I L +N+ G  VGPI VP IT+P I L +N+ 
Sbjct  487  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNAL  545

Query  477  GALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSI-------  529
            G  VGPI +P + ++ I L ++    +N+    +P  P  +        +GS        
Sbjct  546  GG-VGPITVPGVPISRIPLTINIRIPVNITLNELPEPPRHVRRLQFLERMGSCQVVHRGG  604

Query  530  -GPGSISIQLGTPEIPAIPPFFPG----FPPDYVTVSGQIGPITFLSGGYSLPA  578
                 +S + G  +  A+     G      P Y+ ++ +   ++  +   S+PA
Sbjct  605  TRRSCVSGRCGWSQRSAVSTIRSGQRSVRSPVYLVLAARRRCVSGCARRRSMPA  658


 Score = 47.4 bits (111),  Expect = 0.021, Method: Compositional matrix adjust.
 Identities = 52/131 (40%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG  N G  NT +G +    +G + +++++G+GNT     GF       
Sbjct  100  NSGFLNVGPLTSGILNFG--NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  157

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  158  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  217

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  218  GSNNLGFANTG  228


 Score = 41.6 bits (96),  Expect = 1.2, Method: Compositional matrix adjust.
 Identities = 25/50 (50%), Positives = 35/50 (70%), Gaps = 1/50 (2%)

Query  413  FSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVP  462
            F    ++PA  L ++  G++GP+T P ITIP I LGI+ SG+L GPIN+P
Sbjct  2    FPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSL-GPINIP  50


>gi|308370862|ref|ZP_07422988.2| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308330609|gb|EFP19460.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
Length=568

 Score =  967 bits (2501),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 550/552 (99%), Positives = 552/552 (100%), Gaps = 0/552 (0%)

Query  576   LPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  635
             +PAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV
Sbjct  1     MPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  60

Query  636   GGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIE  695
             GGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIE
Sbjct  61    GGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIE  120

Query  696   IAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSG  755
             IAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSG
Sbjct  121   IAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSG  180

Query  756   ILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNL  815
             ILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNL
Sbjct  181   ILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNL  240

Query  816   GNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLT  875
             GNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLT
Sbjct  241   GNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLT  300

Query  876   EALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGF  935
             EALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGF
Sbjct  301   EALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGF  360

Query  936   FNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGS  995
             FNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGS
Sbjct  361   FNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGS  420

Query  996   YNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLI  1055
             YNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLI
Sbjct  421   YNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLI  480

Query  1056  GYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS  1115
             GYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS
Sbjct  481   GYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS  540

Query  1116  LNALGGVGPIVV  1127
             LNALGGVGPIVV
Sbjct  541   LNALGGVGPIVV  552


 Score =  268 bits (686),  Expect = 5e-69, Method: Compositional matrix adjust.
 Identities = 173/280 (62%), Positives = 202/280 (73%), Gaps = 4/280 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  274  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  333

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  334  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  392

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  393  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  452

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  453  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  512

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPI  483
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI
Sbjct  513  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPI  550


 Score =  125 bits (313),  Expect = 9e-26, Method: Compositional matrix adjust.
 Identities = 98/206 (48%), Positives = 120/206 (59%), Gaps = 7/206 (3%)

Query  1257  QGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGL  1312
              G+S+    L I + G     T+   G+++    L + + GG  P T+   G+++    L
Sbjct  22    DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPL  81

Query  1313  NVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNS  1372
              + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNS
Sbjct  82    GIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNS  141

Query  1373  GDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVG  1432
             G G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G
Sbjct  142   GTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG  198

Query  1433  HLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               T+AF+SGV N    L GF    AG
Sbjct  199   LATSAFHSGVGNTDSQLAGFMRNAAG  224


 Score = 83.2 bits (204),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 55/126 (44%), Positives = 81/126 (65%), Gaps = 7/126 (5%)

Query  1086  IPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNA  1141
             +P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++ 
Sbjct  1     MPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDV  60

Query  1142  LGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGV  1199
              GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP IPL ++  G +GPI +P +
Sbjct  61    GGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIP-I  119

Query  1200  PISRIP  1205
              I+  P
Sbjct  120   EIAGTP  125


 Score = 79.3 bits (194),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  486   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  542


 Score = 67.8 bits (164),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 39/82 (48%), Positives = 54/82 (66%), Gaps = 3/82 (3%)

Query  1057  YSDTLSIPAIPLSVEVNGGIGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1114
             + D  S+PAIPL ++V GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP IPL
Sbjct  45    FPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPL  104

Query  1115  SLNALGGVGPIVVPDITIPGIP  1136
              ++  G +GPI +P I I G P
Sbjct  105   GIDVSGSLGPINIP-IEIAGTP  125


 Score = 44.7 bits (104),  Expect = 0.15, Method: Compositional matrix adjust.
 Identities = 29/77 (38%), Positives = 44/77 (58%), Gaps = 5/77 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  479   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  533

Query  1330  IPGSPLNLTANGGLGPI  1346
             IPG PL+L A GG+GPI
Sbjct  534   IPGIPLSLNALGGVGPI  550


 Score = 44.3 bits (103),  Expect = 0.17, Method: Compositional matrix adjust.
 Identities = 51/131 (39%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG   +  GNT +G +    +G + +++++G+GNT     GF       
Sbjct  168  NSGFLNVGPLTSGI--LNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  225

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  226  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  285

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  286  GSNNLGFANTG  296


 Score = 39.7 bits (91),  Expect = 4.1, Method: Compositional matrix adjust.
 Identities = 20/38 (53%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+V ++GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  493   LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVP  530


>gi|306779924|ref|ZP_07418261.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308327166|gb|EFP16017.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
Length=538

 Score =  944 bits (2439),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 537/538 (99%), Positives = 538/538 (100%), Gaps = 0/538 (0%)

Query  589   LGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  648
             LGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG
Sbjct  1     LGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  60

Query  649   YSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTT  708
             YSLPAIPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTT
Sbjct  61    YSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTT  120

Query  709   PSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYN  768
             PSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYN
Sbjct  121   PSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYN  180

Query  769   TSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSG  828
             TSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSG
Sbjct  181   TSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSG  240

Query  829   NVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGG  888
             NVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGG
Sbjct  241   NVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGG  300

Query  889   NNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNS  948
             NNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNS
Sbjct  301   NNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNS  360

Query  949   GNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNP  1008
             GNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNP
Sbjct  361   GNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNP  420

Query  1009  GNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPL  1068
             GNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPL
Sbjct  421   GNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPL  480

Query  1069  SVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIV  1126
             SVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIV
Sbjct  481   SVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIV  538


 Score =  267 bits (683),  Expect = 9e-69, Method: Compositional matrix adjust.
 Identities = 173/280 (62%), Positives = 202/280 (73%), Gaps = 4/280 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  261  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  320

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  321  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  379

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  380  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  439

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  440  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  499

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPI  483
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI
Sbjct  500  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPI  537


 Score =  124 bits (312),  Expect = 1e-25, Method: Compositional matrix adjust.
 Identities = 98/206 (48%), Positives = 120/206 (59%), Gaps = 7/206 (3%)

Query  1257  QGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGL  1312
              G+S+    L I + G     T+   G+++    L + + GG  P T+   G+++    L
Sbjct  9     DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPL  68

Query  1313  NVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNS  1372
              + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNS
Sbjct  69    GIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNS  128

Query  1373  GDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVG  1432
             G G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G
Sbjct  129   GTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG  185

Query  1433  HLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               T+AF+SGV N    L GF    AG
Sbjct  186   LATSAFHSGVGNTDSQLAGFMRNAAG  211


 Score = 79.3 bits (194),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  473   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  529


 Score = 72.8 bits (177),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 49/113 (44%), Positives = 72/113 (64%), Gaps = 7/113 (6%)

Query  1099  VGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-  1152
             +GP  V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP  V PD 
Sbjct  1     LGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDG  60

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIP  1205
              ++P IPL ++  G +GP+  P ITIP IPL ++  G +GPI +P + I+  P
Sbjct  61    YSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIP-IEIAGTP  112


 Score = 67.8 bits (164),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 39/82 (48%), Positives = 54/82 (66%), Gaps = 3/82 (3%)

Query  1057  YSDTLSIPAIPLSVEVNGGIGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGIPL  1114
             + D  S+PAIPL ++V GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP IPL
Sbjct  32    FPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPL  91

Query  1115  SLNALGGVGPIVVPDITIPGIP  1136
              ++  G +GPI +P I I G P
Sbjct  92    GIDVSGSLGPINIP-IEIAGTP  112


 Score = 44.3 bits (103),  Expect = 0.17, Method: Compositional matrix adjust.
 Identities = 29/77 (38%), Positives = 44/77 (58%), Gaps = 5/77 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  466   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  520

Query  1330  IPGSPLNLTANGGLGPI  1346
             IPG PL+L A GG+GPI
Sbjct  521   IPGIPLSLNALGGVGPI  537


 Score = 43.5 bits (101),  Expect = 0.27, Method: Compositional matrix adjust.
 Identities = 51/131 (39%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG   +  GNT +G +    +G + +++++G+GNT     GF       
Sbjct  155  NSGFLNVGPLTSGI--LNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  212

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  213  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  272

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  273  GSNNLGFANTG  283


 Score = 39.7 bits (91),  Expect = 4.3, Method: Compositional matrix adjust.
 Identities = 20/38 (53%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1312  LNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIP  1349
             L+V ++GG  P+ +P  TIPG PL+L A GG+GPI +P
Sbjct  480   LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVP  517


>gi|306803629|ref|ZP_07440297.1| hypothetical protein TMHG_01093 [Mycobacterium tuberculosis SUMu008]
 gi|308349719|gb|EFP38570.1| hypothetical protein TMHG_01093 [Mycobacterium tuberculosis SUMu008]
Length=536

 Score =  939 bits (2428),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/536 (99%), Positives = 536/536 (100%), Gaps = 0/536 (0%)

Query  594   VFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA  653
             +FPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA
Sbjct  1     MFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA  60

Query  654   IPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGF  713
             IPLGIDVGGAIGPLTTPPITIP+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGF
Sbjct  61    IPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGF  120

Query  714   FNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG  773
             FNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG
Sbjct  121   FNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG  180

Query  774   LATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSY  833
             LATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSY
Sbjct  181   LATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSY  240

Query  834   NFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGF  893
             NFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGF
Sbjct  241   NFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGF  300

Query  894   ANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNV  953
             ANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNV
Sbjct  301   ANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNV  360

Query  954   GIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANT  1013
             GIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANT
Sbjct  361   GIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANT  420

Query  1014  GYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVN  1073
             GYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVN
Sbjct  421   GYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVN  480

Query  1074  GGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPD  1129
             GGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPD
Sbjct  481   GGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPD  536


 Score =  270 bits (689),  Expect = 2e-69, Method: Compositional matrix adjust.
 Identities = 174/283 (62%), Positives = 204/283 (73%), Gaps = 4/283 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  256  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  315

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  316  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  374

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  375  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  434

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  435  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  494

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIP  486
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P
Sbjct  495  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVP  535


 Score =  124 bits (312),  Expect = 1e-25, Method: Compositional matrix adjust.
 Identities = 98/206 (48%), Positives = 120/206 (59%), Gaps = 7/206 (3%)

Query  1257  QGFSVNPFGLNIPLSGATNAVTI--PGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGL  1312
              G+S+    L I + G     T+   G+++    L + + GG  P T+   G+++    L
Sbjct  4     DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPL  63

Query  1313  NVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNS  1372
              + + G   P+T P  TIP  PL +  +G LGPINIPI I   PGFGNSTTTPSSGFFNS
Sbjct  64    GIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNS  123

Query  1373  GDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVG  1432
             G G  SGFGNVG G SG WN   N    G SG  NVG L SG+ N GNTVSG  NTST+G
Sbjct  124   GTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLG  180

Query  1433  HLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               T+AF+SGV N    L GF    AG
Sbjct  181   LATSAFHSGVGNTDSQLAGFMRNAAG  206


 Score = 79.3 bits (194),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  468   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  524


 Score = 71.6 bits (174),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 46/108 (43%), Positives = 69/108 (64%), Gaps = 6/108 (5%)

Query  1103  VVPD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPG  1157
             + PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  GG+GP  V PD  ++P 
Sbjct  1     MFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA  60

Query  1158  IPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIP  1205
             IPL ++  G +GP+  P ITIP IPL ++  G +GPI +P + I+  P
Sbjct  61    IPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIP-IEIAGTP  107


 Score = 46.6 bits (109),  Expect = 0.037, Method: Compositional matrix adjust.
 Identities = 30/80 (38%), Positives = 46/80 (58%), Gaps = 5/80 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  461   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  515

Query  1330  IPGSPLNLTANGGLGPINIP  1349
             IPG PL+L A GG+GPI +P
Sbjct  516   IPGIPLSLNALGGVGPIVVP  535


 Score = 43.5 bits (101),  Expect = 0.28, Method: Compositional matrix adjust.
 Identities = 51/131 (39%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG   +  GNT +G +    +G + +++++G+GNT     GF       
Sbjct  150  NSGFLNVGPLTSGI--LNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  207

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  208  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  267

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  268  GSNNLGFANTG  278


>gi|306968018|ref|ZP_07480679.1| hypothetical protein TMIG_02163 [Mycobacterium tuberculosis SUMu009]
 gi|308354358|gb|EFP43209.1| hypothetical protein TMIG_02163 [Mycobacterium tuberculosis SUMu009]
Length=514

 Score =  900 bits (2326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/514 (99%), Positives = 514/514 (100%), Gaps = 0/514 (0%)

Query  615   GPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITI  674
             GPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITI
Sbjct  1     GPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITI  60

Query  675   PSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGF  734
             P+IPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGF
Sbjct  61    PAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGF  120

Query  735   WNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFM  794
             WNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFM
Sbjct  121   WNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFM  180

Query  795   RNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNN  854
             RNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNN
Sbjct  181   RNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNN  240

Query  855   FGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIG  914
             FGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIG
Sbjct  241   FGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIG  300

Query  915   LTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTG  974
             LTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTG
Sbjct  301   LTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTG  360

Query  975   LFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTG  1034
             LFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTG
Sbjct  361   LFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTG  420

Query  1035  ALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLN  1094
             ALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLN
Sbjct  421   ALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLN  480

Query  1095  ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  1128
             ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP
Sbjct  481   ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  514


 Score =  269 bits (688),  Expect = 3e-69, Method: Compositional matrix adjust.
 Identities = 174/283 (62%), Positives = 204/283 (73%), Gaps = 4/283 (1%)

Query  205  SLGLANSGFGQMGAANLGILNLG-SLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
            ++G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG 
Sbjct  235  NIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGT  294

Query  264  GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
            GNIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN
Sbjct  295  GNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGN  353

Query  324  TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN
Sbjct  354  VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  413

Query  384  TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIP  443
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP
Sbjct  414  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIP  473

Query  444  EIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIP  486
             I L +N+ G  VGPI VP IT+P I L +N+ G  VGPI +P
Sbjct  474  GIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVP  514


 Score =  123 bits (308),  Expect = 3e-25, Method: Compositional matrix adjust.
 Identities = 92/180 (52%), Positives = 110/180 (62%), Gaps = 5/180 (2%)

Query  1281  GFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLT  1338
             G+++    L + + GG  P T+   G+++    L + + G   P+T P  TIP  PL + 
Sbjct  9     GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGID  68

Query  1339  ANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNAL  1398
              +G LGPINIPI I   PGFGNSTTTPSSGFFNSG G  SGFGNVG G SG WN   N  
Sbjct  69    VSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  127

Query  1399  QGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAG  1458
               G SG  NVG L SG+ N GNTVSG  NTST+G  T+AF+SGV N    L GF    AG
Sbjct  128   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  185


 Score = 79.7 bits (195),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 41/57 (72%), Positives = 48/57 (85%), Gaps = 0/57 (0%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTIN  1209
             ++IP IPLS+   GG+GPIVVPDITIPGIPLSLNALGGVGPI VP + I  IPL++N
Sbjct  447   LSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLN  503


 Score = 60.8 bits (146),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 38/83 (46%), Positives = 53/83 (64%), Gaps = 4/83 (4%)

Query  1080  VVPD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGIP  1136
             V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP IP
Sbjct  5     VFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIP  64

Query  1137  LSLNALGGVGPIVVPDITIPGIP  1159
             L ++  G +GPI +P I I G P
Sbjct  65    LGIDVSGSLGPINIP-IEIAGTP  86


 Score = 60.1 bits (144),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 36/83 (44%), Positives = 53/83 (64%), Gaps = 4/83 (4%)

Query  1126  VVPD-ITIPGIPLSLNALGGVGPIVV-PD-ITIPGIPLSLNALGGVGPIVVPDITIPGIP  1182
             V PD  ++P IPL ++  GG+GP  V PD  ++P IPL ++  G +GP+  P ITIP IP
Sbjct  5     VFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIP  64

Query  1183  LSLNALGGVGPITVPGVPISRIP  1205
             L ++  G +GPI +P + I+  P
Sbjct  65    LGIDVSGSLGPINIP-IEIAGTP  86


 Score = 46.6 bits (109),  Expect = 0.040, Method: Compositional matrix adjust.
 Identities = 30/80 (38%), Positives = 46/80 (58%), Gaps = 5/80 (6%)

Query  1270  LSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFT  1329
             L G ++ ++IP        L+V ++GG  P+ +P   I    L++   GG  P+ +P  T
Sbjct  440   LIGYSDTLSIPAIP-----LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDIT  494

Query  1330  IPGSPLNLTANGGLGPINIP  1349
             IPG PL+L A GG+GPI +P
Sbjct  495   IPGIPLSLNALGGVGPIVVP  514


 Score = 43.1 bits (100),  Expect = 0.42, Method: Compositional matrix adjust.
 Identities = 51/131 (39%), Positives = 69/131 (53%), Gaps = 19/131 (14%)

Query  282  NSGTGNIGLFNSGTGNIGIGNTGTGNFG---IGNSGTSYNTGIGNTGQANTGF-------  331
            NSG  N+G   SG   +  GNT +G +    +G + +++++G+GNT     GF       
Sbjct  129  NSGFLNVGPLTSGI--LNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGG  186

Query  332  --FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNT-----GFFNPGNLNTGVGNT  384
              FN G AN G  N GN N G +N+GS N G +N GS N      GF N G+ N G GN 
Sbjct  187  TLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNV  246

Query  385  GNVNTGGFNSG  395
            G+ N G  N+G
Sbjct  247  GSNNLGFANTG  257


>gi|289745649|ref|ZP_06505027.1| predicted protein [Mycobacterium tuberculosis 02_1987]
 gi|289758026|ref|ZP_06517404.1| predicted protein [Mycobacterium tuberculosis T85]
 gi|289686177|gb|EFD53665.1| predicted protein [Mycobacterium tuberculosis 02_1987]
 gi|289713590|gb|EFD77602.1| predicted protein [Mycobacterium tuberculosis T85]
 gi|326903523|gb|EGE50456.1| PPE family protein [Mycobacterium tuberculosis W-148]
Length=547

 Score =  805 bits (2078),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 501/532 (95%), Positives = 516/532 (97%), Gaps = 3/532 (0%)

Query  1    MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
            MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP
Sbjct  12   MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  71

Query  61   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
            SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL
Sbjct  72   SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  131

Query  121  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
            VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA
Sbjct  132  VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  191

Query  181  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  240
            QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN
Sbjct  192  QLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGN  251

Query  241  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  300
            VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI
Sbjct  252  VGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGI  311

Query  301  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  360
            GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG
Sbjct  312  GNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTG  371

Query  361  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  420
            DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP
Sbjct  372  DFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP  431

Query  421  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALV  480
            AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG++S+GALV
Sbjct  432  AAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGVSSSGALV  491

Query  481  GPINIPPITLNSIGLELSAFQVINVGSISIPASPL-AIGLFGVNPTVGSIGP  531
            GPIN+PPIT+ +IGL +S+   + VG I++P   + AIGL GV+ +   +GP
Sbjct  492  GPINVPPITVPAIGLGVSSSGAL-VGPINVPPITVPAIGL-GVSSSGALVGP  541


 Score =  306 bits (784),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 199/332 (60%), Positives = 236/332 (72%), Gaps = 6/332 (1%)

Query  850   IGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTG  909
             +G  N GFG +G+ NLG  N G  L    +N G GN+G NN G  N GNGNIGFGNTG G
Sbjct  217   LGLANSGFGQMGAANLGILNLGS-LNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNG  275

Query  910   NIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSG-NYNTGLGNV  968
             NIG GLTGDNQ GFG  NSG+GNIG FNSG GNIG  N+G GN GIGNSG +YNTG+GN 
Sbjct  276   NIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNT  335

Query  969   GNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNI  1028
             G ANTG FN G  NTGIGN G+YNTGS+N G  NTGD N G++NTG+ N G+LNTG GN 
Sbjct  336   GQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNT  395

Query  1029  GDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPG  1088
             G++NTG   SG+YSNG  WRGDYQGLIG+S TL+IPA  L +   G +GPI +P ITIP 
Sbjct  396   GNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPE  455

Query  1089  IPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-VGPIVVPDITIPGIPLSLNALGG-V  1145
             I L +N+ G  VGPI VP IT+P I L +++ G  VGPI VP IT+P I L +++ G  V
Sbjct  456   IGLGINSSGALVGPINVPPITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGALV  515

Query  1146  GPIVVPDITIPGIPLSLNALGG-VGPIVVPDI  1176
             GPI VP IT+P I L +++ G  VGPI VP I
Sbjct  516   GPINVPPITVPAIGLGVSSSGALVGPINVPPI  547


 Score = 67.8 bits (164),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 56/128 (44%), Positives = 78/128 (61%), Gaps = 10/128 (7%)

Query  570  LSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGL-GPFTVFPDGYSLPA  628
             SG  ++PA  L ++  G +GP T+     ++P I LGI+  G L GP  V P   ++PA
Sbjct  424  FSGTLTIPAAGLDLNGLGSVGPITI--PSITIPEIGLGINSSGALVGPINVPP--ITVPA  479

Query  629  IPLGIDVGGGL-GPFTVFPDGYSLPAIPLGIDVGGA-IGPLTTPPITIPSIPLGIDVSGS  686
            I LG+   G L GP  V P   ++PAI LG+   GA +GP+  PPIT+P+I LG+  SG+
Sbjct  480  IGLGVSSSGALVGPINVPP--ITVPAIGLGVSSSGALVGPINVPPITVPAIGLGVSSSGA  537

Query  687  L-GPINIP  693
            L GPIN+P
Sbjct  538  LVGPINVP  545


 Score = 52.4 bits (124),  Expect = 6e-04, Method: Compositional matrix adjust.
 Identities = 60/156 (39%), Positives = 77/156 (50%), Gaps = 18/156 (11%)

Query  720  GTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTST----LGLA  775
            G  GFGN G+G  GF     N    G  N G    G+ N G    G+ NT T    +G +
Sbjct  265  GNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNS  324

Query  776  TSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNF  835
             +++++G+GNT     GF         FN G AN G  N GN N G +N+GS N G +N 
Sbjct  325  GTSYNTGIGNTGQANTGF---------FNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNT  375

Query  836  GSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  871
            GS N      GF N G+ N G GN G+ N G  N+G
Sbjct  376  GSSNT-----GFFNPGNLNTGVGNTGNVNTGGFNSG  406


 Score = 47.8 bits (112),  Expect = 0.017, Method: Compositional matrix adjust.
 Identities = 29/57 (51%), Positives = 36/57 (64%), Gaps = 1/57 (1%)

Query  1153  ITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGG-VGPITVPGVPISRIPLTI  1208
             +TIP   L LN LG VGPI +P ITIP I L +N+ G  VGPI VP + +  I L +
Sbjct  428   LTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGV  484


>gi|340628330|ref|YP_004746782.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340006520|emb|CCC45704.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=3735

 Score =  803 bits (2074),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 696/1506 (47%), Positives = 849/1506 (57%), Gaps = 204/1506 (13%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             MNF  LPPEINS L++ GAGS P+ AAA AWD LA EL SAA SF  VTSGL    W G 
Sbjct  1     MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGA  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             ++AAMAAA APY GWL + AAQA   A QA A VA FEA  AA V PA VA NR  + +L
Sbjct  61    AAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRAL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNL----T  176
               SN  GQNA AIAA+EA YE MWA DV+ M+ YH+GASA A+AL  F+ P Q L     
Sbjct  121   AMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVG  180

Query  177   DLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNF  236
                  L A PA +++  + +  G + N ++GL N G   +GAAN+G  NLG+ N G  NF
Sbjct  181   AFLNALFAGPAKMLS--LNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNF  238

Query  237   --------------------------GLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGL  270
                                       GLGN GS+N GL N G GNIGF NTG+ NIG GL
Sbjct  239   GFGNIGNANFGFANSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGL  298

Query  271   TGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTG  330
             TGDN  G GG NSGTGN+GLFNSGTGN+G  N+GTGNFG+ NSG SYNTG+GN G A+TG
Sbjct  299   TGDNLTGIGGLNSGTGNLGLFNSGTGNVGFFNSGTGNFGVFNSG-SYNTGVGNAGTASTG  357

Query  331   FFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTG  390
              FN G  NTG+ N G+YNTGSFN G+ NTGDFN G+ NTG+ N GN NTGV N+GNVNTG
Sbjct  358   LFNVGGFNTGVANVGSYNTGSFNAGNTNTGDFNPGNVNTGWLNTGNTNTGVANSGNVNTG  417

Query  391   GFNSGNYSNGFFWRGDYQGLIGFSGTLTIPA--AGLDLNGLGSVGPITIPSITI-PEIGL  447
              F SGN+SNG  WRGDY+GL G SG  TIPA   GL+LN  G VGPIT+  I I P I L
Sbjct  418   AFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELN--GGVGPITVLPIQILPTIPL  475

Query  448   GINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGS  507
              I+ +  L GP+ VP I +PA G G  +    VGPI + PITL         F   N  +
Sbjct  476   NIHQTVNL-GPLVVPDIVIPAFGGGT-AIPISVGPITVSPITL---------FPAQNFNT  524

Query  508   ISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPI  567
                      +G+  ++        G++++QLG   I               T   Q  P+
Sbjct  525   TFNVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLTID--------------TRINQQFPV  570

Query  568   TFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLP  627
             T     ++ PA+             T+FP+G S+P  PL +     +G       G+++P
Sbjct  571   TV---NWNTPAV-------------TIFPNGISIPNNPLALLASASIGTPGFTIPGFTIP  614

Query  628   AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSL  687
             A PL                       PL ID+ G I   +TPPITI  IPL +  S ++
Sbjct  615   AAPL-----------------------PLTIDIDGQIDGFSTPPITIDRIPLNLGASVTV  651

Query  688   GPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GN  743
             GPI I  + I  TPGFGN+TT PSSGFFNSG GG SGFGN G+G SG+WN A        
Sbjct  652   GPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAG  711

Query  744   SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLF  803
             SGF N G L SG+LNFG+ VSGLYNT  L   T A  SG+GN   QL+G    ++ GT  
Sbjct  712   SGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGL---SSAGTAL  768

Query  804   NFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSN  863
             N        +NLG A++G  NVG GNVG+ N G+ NIG+ + G GN+GS N GFGN+G  
Sbjct  769   NQSL----IINLGLADVGSVNVGFGNVGNVNLGAANIGDLNVGLGNVGSGNVGFGNIGDA  824

Query  864   NLGFANTGPGLTEA-LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVG  922
             N G  N G     A + NIG GN G  N GF N+G GNIGFGNTGT N+G GLTGDNQ G
Sbjct  825   NFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGFGLTGDNQTG  884

Query  923   FGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVN  982
              G LNSG+GNIG FNSG GN+G FNSG GN G+ NSG YNTG+GN G  +TGLFN GN N
Sbjct  885   IGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGGYNTGIGNGGTGSTGLFNAGNFN  944

Query  983   TGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYS  1042
             TG+ N GSYNTGS+N GDTNTG  NPG+ NTG+ N G+ NTG  N G +NTGA I+G+ S
Sbjct  945   TGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGTVNTGAFITGNDS  1004

Query  1043  NGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL-NALGGVGP  1101
             NGILWRG+++GL       +I   PL+    GGIGP+ V  + I     ++ NA  G+GP
Sbjct  1005  NGILWRGNFEGLFSAYLGFTIEQFPLTYHAVGGIGPLHVAPVPISAAHFNITNASIGLGP  1064

Query  1102  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLS  1161
               +P+I IP IP+ +    G+G   + D+T      +LNAL G            GI LS
Sbjct  1065  FTIPEIHIPKIPIDVLGSVGLGQTTISDVT------ALNALNG------------GIGLS  1106

Query  1162  LNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNEL  1221
             + +     P +           S+   G   P  + G  IS + +T              
Sbjct  1107  IGSFKFNDPFI-----------SIANFGNPNPPAI-GFFISNLSIT--------------  1140

Query  1222  PFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPG  1281
                ++G+  G   PIPLS            L  G   +++ P G  IP   A   VT+  
Sbjct  1141  GPQISGLSIGS--PIPLS------------LALGTTTWTLFPNGWTIP---AQTPVTL--  1181

Query  1282  FAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVP--------LSGGTSPVTI--PGFTIP  1331
                        LSGG  P     F   P GL  P        LSGGT P T+   GF I 
Sbjct  1182  ----------GLSGGNDP-----FTFFPGGLTFPKASAGVINLSGGTDPFTLLPNGFQIT  1226

Query  1332  GSPLNLTANGGLGPINIP-INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGL  1390
               P+        G I IP IN+ + PGFGN+TT PSSGFFNSGDG  SGFGN G G SG 
Sbjct  1227  TVPVLWDGTVLFGSIQIPIINVPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGW  1286

Query  1391  WNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLL  1450
             WNQ    + G  SG  N G L SGV N G+ VSG  NT  +   T A  SG+ N+G+ L 
Sbjct  1287  WNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLS  1346

Query  1451  GFFSPG  1456
             G FS G
Sbjct  1347  GLFSAG  1352


 Score =  687 bits (1772),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 582/1309 (45%), Positives = 720/1309 (56%), Gaps = 234/1309 (17%)

Query  210   NSGFGQMGAANLGILN--LGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIG  267
             N GFG +G  N+G  N  LG+L PG  N GLGN GSNNVG GN G GNIGFGNTG  N+G
Sbjct  2018  NVGFGNLGHGNVGFGNSGLGAL-PGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLG  2076

Query  268   FGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQA  327
              GLTGDNQ GFGG NSG GN+GLFNSGTGNIG  NTGTGN+G+ NSG SYNTGIGN+G  
Sbjct  2077  IGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSG-SYNTGIGNSGTG  2135

Query  328   NTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNV  387
             +TG FNAG  NTG+ N G+YNTGS N G+ NTG FN G+ NTG+FN G+ NTG+ NTGNV
Sbjct  2136  STGLFNAGSFNTGLANAGSYNTGSVNAGNTNTGGFNPGNVNTGWFNAGHTNTGLFNTGNV  2195

Query  388   NTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGL  447
             NTG FNSG+++NG  W GD+ GL GFS ++ I  +                  T+ +I  
Sbjct  2196  NTGAFNSGSFNNGALWTGDHHGLFGFSYSIEITGS------------------TLVDINE  2237

Query  448   GINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGS  507
              +N     +GPI++  I +P + L        +GP  IP                     
Sbjct  2238  TVN-----LGPIHIDQIDIPGMSLFDIHELVNIGPFTIP--------------------Q  2272

Query  508   ISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPP--FFPGFPPDYVTVSGQIG  565
             I +PA PL I                        E   IPP  F PG     +T+ GQ  
Sbjct  2273  IDVPAIPLDI-----------------------HESTVIPPIVFLPG-----MTIGGQTY  2304

Query  566   PI----------------------------------TFLSGGY-SLPAIPLGIDVG---G  587
              I                                  T +SGG+ + P   + I  G   G
Sbjct  2305  TIPLNTPPAPAPPPFRLPLLFVNALGDNWIIGASNSTGMSGGFVTAPTQGILIHTGPSSG  2364

Query  588   GLGPFTVFPDGYSLPAI-----PLGIDVGGGLGPFTVFPDGYSLP--AIPLGIDVGGGLG  640
               G   +     ++P I     PL IDV GGL  FT+FP G ++P  AIPL ID  G L 
Sbjct  2365  STGSLAITFAAVTIPTIMTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLD  2424

Query  641   PFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTP  700
             P T+FP G+++  +PL                   S+ L I V  S  PI   I +  TP
Sbjct  2425  PITIFPGGFTIDPLPL-------------------SLALNISVPDSSVPI---IIVPPTP  2462

Query  701   GFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGIL  757
             GFGN+T TPSSGFFNSG GG SGFGN G+G SG+WN A +      SG LN G L SG+L
Sbjct  2463  GFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHSAVLGAGSGVLNAGTLHSGVL  2522

Query  758   NFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGN  817
             N G+ +SGLYNTS +GL T A  SG+GN   QL+G +   A GT+ N        LN+G 
Sbjct  2523  NVGSGISGLYNTSIVGLGTPALVSGLGNVGQQLSGVL---ASGTVLNQSL----ILNVGL  2575

Query  818   ANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEA  877
             A++G+YN+G GNVG  N G+ NIG+ + G GN+G+ N GFGN+G  N+GFAN+G G    
Sbjct  2576  ADVGNYNLGLGNVGDLNLGAANIGDLNLGLGNVGNGNVGFGNIGHGNVGFANSGLGALPG  2635

Query  878   LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFN  937
             + NIG GN G NN G AN+G GNIGFGNTGT N+GIGLTGDNQ GFG LNSG+GN+G FN
Sbjct  2636  IGNIGLGNAGSNNVGLANMGVGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFN  2695

Query  938   SGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYN  997
             SG GN+GFFNSG GN G+ NSG++NTG+GN G  +TGLFN G  NTG+ NAGSYNTGS+N
Sbjct  2696  SGTGNVGFFNSGTGNWGLFNSGSFNTGVGNSGTGSTGLFNAGGFNTGLANAGSYNTGSFN  2755

Query  998   AGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGY  1057
             AGDTNTGD NPG+ NTG+ N G+ NTG  N G+++TGAL+SG++SNGILWRG+Y+GL+ Y
Sbjct  2756  AGDTNTGDFNPGSINTGWFNTGNSNTGIANAGNVDTGALMSGNFSNGILWRGNYEGLVSY  2815

Query  1058  SDTLSIPAIP-LSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSL  1116
             +  L +P I  L     G  GP++VP I +P I   L     +G   +P I IP +  ++
Sbjct  2816  TYGLDVPRITILDAHFTGAFGPVIVPPIPVPAINAHLTGNVAMGAFTIPQIDIPALQPNV  2875

Query  1117  NALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDI  1176
                 G GPI VP + IP +  +   L     +     T P I  + + L G      P  
Sbjct  2876  TGSVGFGPIAVPSVAIPALNAARAVLDMAASVGASSETEPFIVWTSSGLIG------PTW  2929

Query  1177  TIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNE--LPFNVAGIFTGYIG  1234
                G   S   L   G IT      S IP T++   PV+   N     FN   +    I 
Sbjct  2930  YAVGRSYSFGDLFPSGNIT------SGIP-TLSTTGPVHAVFNAATQAFNTPALTLHQI-  2981

Query  1235  PIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTI-PG---FAINPFGLN  1290
                                         P G  +P  G+ +A+T+ PG   F  N   LN
Sbjct  2982  ----------------------------PVGFQVP--GSIDAITLFPGGLTFPANSL-LN  3010

Query  1291  VPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPI--NI  1348
             + +  GT   TIP                         T P  P N  A+G L  I  NI
Sbjct  3011  LDVFVGTPGATIP-----------------------AITFPEIPAN--ADGELYVIASNI  3045

Query  1349  P-INITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYN  1407
             P INI   PGFGN+TTTPSSGFFN+G G  SGFGN G  +SG WNQ   AL G  SGI N
Sbjct  3046  PLINIPPTPGFGNTTTTPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIAN  3105

Query  1408  VGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPG  1456
              G L+SGV NLG+ +SG  NTST+   T A  SGV N+GQ L G FS G
Sbjct  3106  AGTLSSGVLNLGSGLSGIYNTSTLPLGTPALVSGVGNVGQQLSGLFSAG  3154


 Score =  616 bits (1588),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 576/1287 (45%), Positives = 722/1287 (57%), Gaps = 177/1287 (13%)

Query  201   LANLSLGLANSGFGQMGAANLGILNLGSLN------PGGNNFGLGNVGSNNVGLGNTGNG  254
             + +L+LGL N G G +G  N+G  N+G  N      PG  N GLGN GSNNVGL N G G
Sbjct  2598  IGDLNLGLGNVGNGNVGFGNIGHGNVGFANSGLGALPGIGNIGLGNAGSNNVGLANMGVG  2657

Query  255   NIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSG  314
             NIGFGNTG  N+G GLTGDNQ GFGG NSG GN+GLFNSGTGN+G  N+GTGN+G+ NSG
Sbjct  2658  NIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNVGFFNSGTGNWGLFNSG  2717

Query  315   TSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNP  374
              S+NTG+GN+G  +TG FNAG  NTG+ N G+YNTGSFN G  NTGDFN GS NTG+FN 
Sbjct  2718  -SFNTGVGNSGTGSTGLFNAGGFNTGLANAGSYNTGSFNAGDTNTGDFNPGSINTGWFNT  2776

Query  375   GNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAG-LDLNGLGSVG  433
             GN NTG+ N GNV+TG   SGN+SNG  WRG+Y+GL+ ++  L +P    LD +  G+ G
Sbjct  2777  GNSNTGIANAGNVDTGALMSGNFSNGILWRGNYEGLVSYTYGLDVPRITILDAHFTGAFG  2836

Query  434   PITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGAL-VGPINIPPITLNS  492
             P+ +P I +P I   +  + A+ G   +P I +PA  L  N TG++  GPI +P      
Sbjct  2837  PVIVPPIPVPAINAHLTGNVAM-GAFTIPQIDIPA--LQPNVTGSVGFGPIAVP------  2887

Query  493   IGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPG  552
                           S++IPA   A  +  +  +VG+                   PF   
Sbjct  2888  --------------SVAIPALNAARAVLDMAASVGAS--------------SETEPFI--  2917

Query  553   FPPDYVTVSGQIGPITFLSG-GYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVG  611
                   T SG IGP  +  G  YS   +               FP G     IP     G
Sbjct  2918  ----VWTSSGLIGPTWYAVGRSYSFGDL---------------FPSGNITSGIPTLSTTG  2958

Query  612   GGLGPFTVFPDGYSLPA-----IPLGIDVGGGLGPFTVFPDGYSLPAIPL-GIDVGGAIG  665
                  F      ++ PA     IP+G  V G +   T+FP G + PA  L  +DV     
Sbjct  2959  PVHAVFNAATQAFNTPALTLHQIPVGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTP  3018

Query  666   PLTTPPITIPSIPLGIDVSGSLGPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGF  724
               T P IT P IP   D    +   NIP I I  TPGFGN+TTTPSSGFFN+G GG SGF
Sbjct  3019  GATIPAITFPEIPANADGELYVIASNIPLINIPPTPGFGNTTTTPSSGFFNTGAGGGSGF  3078

Query  725   GNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHS  781
             GN G+  SG+WN A        SG  N G L+SG+LN G+ +SG+YNTSTL L T A  S
Sbjct  3079  GNFGANMSGWWNQAHTALAGAGSGIANAGTLSSGVLNLGSGLSGIYNTSTLPLGTPALVS  3138

Query  782   GVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIG  841
             GVGN   QL+G     + GT+ N G      +N+G AN+G++N G GNVG +N G+ NIG
Sbjct  3139  GVGNVGQQLSGLF---SAGTVLNQG---SSIVNIGLANVGNHNAGFGNVGEFNLGAANIG  3192

Query  842   NGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALH-NIGFGNIGGNNYGFANIGNGN  900
               + GFGNIG  N GFGN+G+ N GF N+G     A   NIGF N G NN+G AN+G GN
Sbjct  3193  ELNLGFGNIGGGNLGFGNIGNANFGFGNSGLAAGLAGLGNIGFANAGSNNFGLANMGIGN  3252

Query  901   IGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGN  960
             +G  NTGT N+GIGLTGDNQ G G LNSG+GN+G FNSG GN+GFFN+G GN G+ NSG+
Sbjct  3253  VGLANTGTNNLGIGLTGDNQTGIGGLNSGTGNVGLFNSGTGNVGFFNTGTGNFGLFNSGS  3312

Query  961   YNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGD  1020
             YNTG+GN G A+TGL N G  NTGI NAG +NTGS+NAG+TNTGD NPG+ NTG+ N G+
Sbjct  3313  YNTGIGNSGVASTGLVNAGGFNTGIANAGHHNTGSFNAGNTNTGDGNPGSINTGWFNTGN  3372

Query  1021  LNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIP-LSVEVNGGIGP-  1078
              NTG  N G++NTGALI+G++SNGILWRG+Y+GL G+S   +IP  P +  +V GGIGP 
Sbjct  3373  ANTGVANAGNVNTGALIAGNFSNGILWRGNYEGLAGFSVGYAIPLFPAVGADVTGGIGPA  3432

Query  1079  IVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDI--TIPGIP  1136
              +VP I IP IPL   A+G +GPI +PDI IP I L +     VGPI V  I  TIPG  
Sbjct  3433  TIVPPIHIPSIPLGFAAIGDIGPITIPDIPIPSIHLGIAPTFDVGPITVDPITLTIPGFS  3492

Query  1137  LSLNALGGVGPIVVPDITIPGIPLSLNALGG--VGPIVVPDITIPGIPLSLNALGGVGPI  1194
             +              D  I  I ++  +  G  V P   P                VGP 
Sbjct  3493  V--------------DAAISEIRMTAGSSSGFKVRPSFSP--------------AAVGPD  3524

Query  1195  TVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLES  1254
               PG  +S +                 PF VA        PI L+   L     G T+ +
Sbjct  3525  GTPGGEVSILQ----------------PFTVA--------PINLNPTTL--HFPGFTIPT  3558

Query  1255  GIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNV  1314
             G       P  + +PLS     +TIPGF                  TIPG  + P     
Sbjct  3559  G-------PIHIGLPLS-----LTIPGF------------------TIPGGTLIPQLPLG  3588

Query  1315  PLSGGTSP-VTIPGFTIPGSPLNLTANGGLGPINIPI-NITSAPGFGNSTTTPSSGFFNS  1372
                 G +P   +P   I   P+ L A+  +GP+++PI     APGFGN TT PSSGFFN+
Sbjct  3589  LGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNT  3648

Query  1373  GDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVG  1432
             G G  SGF N G G+SG+ N + + L G  SG  N G   SG+ N G  +SG  NT T+G
Sbjct  3649  GGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLG  3708

Query  1433  HLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
              +T+AF SG  N+GQ L G    G GP
Sbjct  3709  LVTSAFVSGFMNVGQQLSGLLFAGTGP  3735


 Score =  595 bits (1535),  Expect = 2e-167, Method: Compositional matrix adjust.
 Identities = 550/1272 (44%), Positives = 690/1272 (55%), Gaps = 177/1272 (13%)

Query  205   SLGLANSGFGQMGAANLGILNLGSLN--PGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTG  262
             ++G  N GFG +G AN G+ N G      G  N GLGN GS NVG GN G GNIGFGNTG
Sbjct  810   NVGSGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTG  869

Query  263   NGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIG  322
               N+GFGLTGDNQ G GG NSG GNIGLFNSGTGN+G+ N+GTGNFG+ NSG  YNTGIG
Sbjct  870   TNNLGFGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSG-GYNTGIG  928

Query  323   NTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVG  382
             N G  +TG FNAG  NTG+ N G+YNTGSFN+G  NTG FN GS NTG+FN GN NTGV 
Sbjct  929   NGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVA  988

Query  383   NTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI  442
             N+G VNTG F +GN SNG  WRG+++GL       TI    L  + +G +GP+ +  + I
Sbjct  989   NSGTVNTGAFITGNDSNGILWRGNFEGLFSAYLGFTIEQFPLTYHAVGGIGPLHVAPVPI  1048

Query  443   PEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQV  502
                   I ++   +GP  +P I +P I            PI++    L S+GL  +    
Sbjct  1049  SAAHFNITNASIGLGPFTIPEIHIPKI------------PIDV----LGSVGLGQTTISD  1092

Query  503   INVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSG  562
             +   +       L+IG F  N    SI         G P  PAI     GF    ++++G
Sbjct  1093  VTALNALNGGIGLSIGSFKFNDPFISIA------NFGNPNPPAI-----GFFISNLSITG  1141

Query  563   QIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPA-IPLGIDVGGGLGPFTVFP  621
                 I+ LS G  +P     + +  G   +T+FP+G+++PA  P+ + + GG  PFT FP
Sbjct  1142  P--QISGLSIGSPIP-----LSLALGTTTWTLFPNGWTIPAQTPVTLGLSGGNDPFTFFP  1194

Query  622   DGYSLPAIPLG-IDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLG  680
              G + P    G I++ GG  PFT+ P+G+ +  +P+  D     G +  P I +P+    
Sbjct  1195  GGLTFPKASAGVINLSGGTDPFTLLPNGFQITTVPVLWDGTVLFGSIQIPIINVPA----  1250

Query  681   IDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGN  740
                               TPGFGN+TT PSSGFFNSG GG SGFGN G+G SG+WN A  
Sbjct  1251  ------------------TPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQT  1292

Query  741   L---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNA  797
                   SGF N G L SG+LNFG+ VSGLYNT  L   T A  SG+GN   QL+G     
Sbjct  1293  EVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLFSAG  1352

Query  798   AG---GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNN  854
                    + N G A+ G++N+G  N+GD+N+G+ NVG  N G GNIG G+ GFGNIG  N
Sbjct  1353  TALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANVGGQNLGLGNIGGGNVGFGNIGDAN  1412

Query  855   FGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIG  914
             FG GN G    G A  G        NIG GN G  N GF N+G GNIGFGNTGT N+G G
Sbjct  1413  FGLGNAGLA-AGLAGVG--------NIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGFG  1463

Query  915   LTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTG  974
             LTGDNQ G G LNSG+GNIG FNSG GN+G FNSG GN G+ NSG YNTG+GN G  +TG
Sbjct  1464  LTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGGYNTGIGNGGTGSTG  1523

Query  975   LFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTG  1034
             LFN GN NTG+ N GSYNTGS+N GDTNTG  NPG+ NTG+ N G+ NTG  N G +NTG
Sbjct  1524  LFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGTVNTG  1583

Query  1035  ALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITI-PGIPLSL  1093
             A I+G+ SNGILWRG+++GL G +  ++IP  P+     GGIGPI++PD TI P I L +
Sbjct  1584  AFIAGNDSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGI  1643

Query  1094  NALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALG-----GVGPI  1148
                   G   VPDI IP I +  +    VG       T P   L L+ALG       GPI
Sbjct  1644  TGQANYG-FAVPDIPIPAIHIDFDGAADVG------FTAPATTL-LSALGITGQFRFGPI  1695

Query  1149  VVPDITIP--GIPLSLNALGGVGPIVVPDITIP-----GIPLSLNALGGVGPITVPGVPI  1201
              V ++ +    + L L  L    P   PD TI       IPL+   LGG           
Sbjct  1696  TVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGG-----------  1744

Query  1202  SRIPLTINIRIPVNITLN--ELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGF  1259
                     + +P+  T++  ELP             I  S  +           S I G 
Sbjct  1745  --------LALPLQQTIDAIELP------------GIAFSQSIPIDIPPIDIPASTINGI  1784

Query  1260  SVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGG  1319
             S++   + I +S    AVTI G  I+P  LN  +     P+ I                 
Sbjct  1785  SMSEV-VPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINI-----------------  1826

Query  1320  TSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASG  1379
              S + IP                             PGFGNST  PSSGFFN+G G  SG
Sbjct  1827  -SIIDIPAL---------------------------PGFGNSTELPSSGFFNTGGGGGSG  1858

Query  1380  FGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFN  1439
               N G G+SGL NQ  + + G +SG+ N G LASGV N G  +SG  N ST+G   A   
Sbjct  1859  IANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVI-  1917

Query  1440  SGVNNIGQMLLG  1451
             SG  N+G  + G
Sbjct  1918  SGFGNLGNHVSG  1929


 Score =  571 bits (1471),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 557/1335 (42%), Positives = 700/1335 (53%), Gaps = 215/1335 (16%)

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGN--------------------NFG------  237
             ++LGLA+ G   +G  N+G  NLG+ N GG                     NFG      
Sbjct  1361  INLGLADVGSVNVGFGNVGDFNLGAANVGGQNLGLGNIGGGNVGFGNIGDANFGLGNAGL  1420

Query  238   -----------LGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTG  286
                        LGN GS NVG GN G GNIGFGNTG  N+GFGLTGDNQ G GG NSG G
Sbjct  1421  AAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGFGLTGDNQTGIGGLNSGAG  1480

Query  287   NIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGN  346
             NIGLFNSGTGN+G+ N+GTGNFG+ NSG  YNTGIGN G  +TG FNAG  NTG+ N G+
Sbjct  1481  NIGLFNSGTGNVGLFNSGTGNFGLFNSG-GYNTGIGNGGTGSTGLFNAGNFNTGVANPGS  1539

Query  347   YNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGD  406
             YNTGSFN+G  NTG FN GS NTG+FN GN NTG+ N+G VNTG F +GN SNG  WRG+
Sbjct  1540  YNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGTVNTGAFIAGNDSNGILWRGN  1599

Query  407   YQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-PEIGLGINSSGALVGPINVPPIT  465
             ++GL G +  +TIP   +     G +GPI IP  TI P I LGI  +G       VP I 
Sbjct  1600  FEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGI--TGQANYGFAVPDIP  1657

Query  466   VPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNP-  524
             +PAI   I+  GA       P  TL      LSA  +               G F   P 
Sbjct  1658  IPAI--HIDFDGAADVGFTAPATTL------LSALGI--------------TGQFRFGPI  1695

Query  525   TVGSIGPGSISIQLGTPEIPAIPPFFPG-FPPDYVTVSGQIGPITFLSGGYSLPAIPLGI  583
             TV ++     ++ L   ++  +   FP  FP   ++V  Q+             AIPL  
Sbjct  1696  TVSNVQLNPFNVNL---KLQFLHDAFPNEFPDPTISVQIQV-------------AIPLTS  1739

Query  584   DVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFT  643
                GGL             A+PL   +           D   LP I     +   + P  
Sbjct  1740  ATLGGL-------------ALPLQQTI-----------DAIELPGIAFSQSIPIDIPPID  1775

Query  644   VFP---DGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIP-IEIAGT  699
             +     +G S+  + + IDV   I  +T     I  IPL  DV  S GPINI  I+I   
Sbjct  1776  IPASTINGISMSEV-VPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPAL  1834

Query  700   PGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIA-----GNLGNSGFLNVGPLTS  754
             PGFGNST  PSSGFFN+G GG SG  N G+G SG  N A     G L  SG  N G L S
Sbjct  1835  PGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTL--SGLGNAGSLAS  1892

Query  755   GILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLN  814
             G+LN G  +SG++N STLG A  A  SG GN  + ++G   +     L + G    G  +
Sbjct  1893  GVLNSGVDISGMFNVSTLGSA-PAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPS  1951

Query  815   LGNANLGDYN-------VGSGNVGSYNFGSGNIGNGSFG--------------------F  847
             + +A + +         V  GNVGSYN G  N+G+ + G                     
Sbjct  1952  IIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNVGNLNLGGGNLGGQNLGL  2011

Query  848   GNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTG  907
             GN+G  N GFGN+G  N+GF N+G G    + NIG GN G NN GF N+G GNIGFGNTG
Sbjct  2012  GNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTG  2071

Query  908   TGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGN  967
             T N+GIGLTGDNQ GFG LNSG+GN+G FNSG GNIGFFN+G GN G+ NSG+YNTG+GN
Sbjct  2072  TNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGN  2131

Query  968   VGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGN  1027
              G  +TGLFN G+ NTG+ NAGSYNTGS NAG+TNTG  NPGN NTG+ N G  NTG  N
Sbjct  2132  SGTGSTGLFNAGSFNTGLANAGSYNTGSVNAGNTNTGGFNPGNVNTGWFNAGHTNTGLFN  2191

Query  1028  IGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGI--GPIVVPDIT  1085
              G++NTGA  SGS++NG LW GD+ GL G+S ++ I    L V++N  +  GPI +  I 
Sbjct  2192  TGNVNTGAFNSGSFNNGALWTGDHHGLFGFSYSIEITGSTL-VDINETVNLGPIHIDQID  2250

Query  1086  IPGIPL-SLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIV-VPDITIPGIPLSLNALG  1143
             IPG+ L  ++ L  +GP  +P I +P IPL ++    + PIV +P +TI G   ++    
Sbjct  2251  IPGMSLFDIHELVNIGPFTIPQIDVPAIPLDIHESTVIPPIVFLPGMTIGGQTYTIPLNT  2310

Query  1144  GVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISR  1203
                             L +NALG        D  I G   S    GG       G+ I  
Sbjct  2311  PP---APAPPPFRLPLLFVNALG--------DNWIIGASNSTGMSGGFVTAPTQGILIHT  2359

Query  1204  IPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNP  1263
              P + +           + F    I T    PIPL   V G          G+  F++ P
Sbjct  2360  GPSSGSTGSL------AITFAAVTIPTIMTSPIPLKIDVSG----------GLPAFTLFP  2403

Query  1264  FGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI--PGFAINPFGLNVPLSGGTS  1321
              GLNIP               N   L +  SG   P+TI   GF I+P  L++ L+    
Sbjct  2404  GGLNIPQ--------------NAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALN----  2445

Query  1322  PVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFG  1381
              +++P  ++P                  I +   PGFGN+T TPSSGFFNSG G  SGFG
Sbjct  2446  -ISVPDSSVP-----------------IIIVPPTPGFGNATATPSSGFFNSGAGGVSGFG  2487

Query  1382  NVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSG  1441
             N G G SG WNQ  +A+ G  SG+ N G L SGV N+G+ +SG  NTS VG  T A  SG
Sbjct  2488  NFGAGSSGWWNQAHSAVLGAGSGVLNAGTLHSGVLNVGSGISGLYNTSIVGLGTPALVSG  2547

Query  1442  VNNIGQMLLGFFSPG  1456
             + N+GQ L G  + G
Sbjct  2548  LGNVGQQLSGVLASG  2562


>gi|289747171|ref|ZP_06506549.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289687699|gb|EFD55187.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=2137

 Score =  800 bits (2066),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/1510 (45%), Positives = 846/1510 (57%), Gaps = 208/1510 (13%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             M F  LPPEINS L++ GAGS P+ AAA AWD LA EL SAA SF  VTSGL    W G 
Sbjct  72    MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGA  131

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             ++AAMAAA APY GWL + AA A+  A QA  +V  FEA  AA V PALVAANR+ LV+L
Sbjct  132   AAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVAL  191

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLT----  176
               SN  GQN PAIAA EA YE MWA DV+ M+ YH+GASA A+AL  F+ P Q L     
Sbjct  192   AVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVG  251

Query  177   DLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNF  236
                  L A+PA  ++  + +  G + N ++GL N G   +GA N+G  NLG  N GG N 
Sbjct  252   AFLTALFASPAKALS--LNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNV  309

Query  237   GLGNVGSNNVGLGNT---------------------------GNGNIGFGNTGNGNIGFG  269
             G GN+G+ NVG GN+                           G GNIGFGNTG  N+G G
Sbjct  310   GFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVG  369

Query  270   LTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANT  329
             LTG++  G GG NSGTGNIGLFNSGTGN+G  N+GTGNFG+ NSG +YNTG+GN G A+T
Sbjct  370   LTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSG-NYNTGVGNAGTAST  428

Query  330   GFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNT  389
             G FNAG  NTG+ N G+YNTGSFN G  NTG FN G  NTG+ N GN NTG+ N+GNVNT
Sbjct  429   GLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNT  488

Query  390   GGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-PEIGLG  448
             G F SGN++NG  W GDYQGL G S   +IPA  + L   G +GPITI  I I P I L 
Sbjct  489   GAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLS  548

Query  449   INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITL--NSIGLELSAFQVINVG  506
             I+ +  L GP+ VP I +PA G GI     +   + I PITL      +    F   ++G
Sbjct  549   IHQTVNL-GPLVVPDIVIPAFGGGIGIPINIGP-LTITPITLFAQQTFVNQLPFPTFSLG  606

Query  507   SISIPASPLAIGLFGVN-PTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
              I+IP     I  F  N   V  IGP  I   +  P  P I                   
Sbjct  607   KITIPQ----IQTFDSNGQLVSFIGPIVIDTTIPGPTNPQID------------------  644

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
                 L+  +  P             P T+FP+G S P  PLG+ V       ++   G++
Sbjct  645   ----LTIRWDTP-------------PITLFPNGISAPDNPLGLLV-----SVSISNPGFT  682

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPA--IPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             +P                    G+S+PA  +PL ID+ G I   +TPPITI  IPL +  
Sbjct  683   IP--------------------GFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGG  722

Query  684   SGSLGPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  741
               ++GPI I  + I   PG GN+TT PSSGFFNSG GG SGFGNVG+G SG+WN A +  
Sbjct  723   GVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSAL  782

Query  742   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
                 SG  NVG L SG+LN G+ +SG YNTS L   T A  SG+GN   QL+G   +AAG
Sbjct  783   LGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGV--SAAG  840

Query  800   GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGN  859
              TL +    N     LG AN+G++N G GNVG  N G+ NIG  + G GN+G  N G GN
Sbjct  841   TTLRSMLAGN-----LGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGN  895

Query  860   VGSNNLGFANTGPGLTEA-LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGD  918
             +G  NLGFAN G     A + N+GFGN G NNYG AN+G GNIGF NTGTGNIGIGL GD
Sbjct  896   IGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGD  955

Query  919   NQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNT  978
             ++ G G LNSG GNIG FNSG GN+GFFNSG GN GIGNSG +NTG+GN G A+TGLFN 
Sbjct  956   HRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNA  1015

Query  979   GNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALIS  1038
             G+ +TGI N G YNTGS+NAGDTNTG  NPG  NTG+ N G  NTG  N G   TGA ++
Sbjct  1016  GSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMT  1075

Query  1039  GSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL-NALG  1097
             G YSNG+LWRG Y+GL+G     +I   P++V   GG+GP+ V  + +P + + + +A  
Sbjct  1076  GDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATV  1135

Query  1098  GVGPIVVPDITIPGIPL-----SLN-ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  1151
             G+GP  VP I+IP +P+     S++ A   + PI   D     I L L       P +  
Sbjct  1136  GLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITI  1195

Query  1152  DITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIR  1211
             D        +   + GV  + + +I +PG+ +S       G I V   P   IPLT+N+ 
Sbjct  1196  D--------AFQVVAGV--LFLENIIVPGLTVS-------GQILVTPTP---IPLTLNLD  1235

Query  1212  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGT-----LESGIQGFSVNPFGL  1266
                                      P + F  G T+   T     +E    GF+  P GL
Sbjct  1236  T-----------------------TPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGL  1272

Query  1267  NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIP  1326
               P + A   VT         GL+V L           F + P G  +     T P T  
Sbjct  1273  TFPRASA--GVT---------GLSVGLD---------AFTLLPDGFTLD----TVPATFD  1308

Query  1327  GFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPG  1386
             G  + G                  ++ + PGFGN+TT PSSGFFN+G G  SGF NVG G
Sbjct  1309  GTILIGDIPIPII-----------DVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAG  1357

Query  1387  ISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIG  1446
              SG WNQ  + L G  SG+ N G L+SGV N+G+ +SG+ NTST+G  T A  SG+ N+G
Sbjct  1358  TSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLG  1417

Query  1447  QMLLGFFSPG  1456
             Q L GF + G
Sbjct  1418  QQLSGFLANG  1427


 Score =  635 bits (1637),  Expect = 2e-179, Method: Compositional matrix adjust.
 Identities = 502/1172 (43%), Positives = 669/1172 (58%), Gaps = 162/1172 (13%)

Query  163   SALTPFTAPP--QNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAAN  220
             +++ PF  P     + +L  QL+      V+AA T+ + +LA  +LGLAN G    G  N
Sbjct  812   TSVLPFGTPAAVSGIGNLGQQLSG-----VSAAGTTLRSMLAG-NLGLANVGNFNTGFGN  865

Query  221   LGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGN-------------------------  255
             +G +NLG+ N GG+N GLGNVG  N+GLGN G+GN                         
Sbjct  866   VGDVNLGAANIGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGAAGVGNVGFGNAGI  925

Query  256   ------------IGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNT  303
                         IGF NTG GNIG GL GD++ G GG NSG GNIGLFNSGTGN+G  N+
Sbjct  926   NNYGLANMGVGNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNS  985

Query  304   GTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFN  363
             GTGNFGIGNSG  +NTGIGN+G A+TG FNAG  +TGI NTG+YNTGSFN G  NTG FN
Sbjct  986   GTGNFGIGNSG-RFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFN  1044

Query  364   TGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAG  423
              G  NTG+FN G+ NTG+ N G   TG F +G+YSNG  WRG Y+GL+G     TI    
Sbjct  1045  PGGINTGWFNTGHANTGLANAGTFGTGAFMTGDYSNGLLWRGGYEGLVGVRVGPTISQFP  1104

Query  424   LDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLG-----INSTGA  478
             + ++ +G VGP+ +  + +P + + I  +   +GP  VPPI++P++ +      ++    
Sbjct  1105  VTVHAIGGVGPLHVAPVPVPAVHVEITDATVGLGPFTVPPISIPSLPIASITGSVDLAAN  1164

Query  479   LVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQL  538
              + PI        SIGL L  F++ +   I+I A  +  G+  +   +            
Sbjct  1165  TISPIRALDPLAGSIGLFLEPFRLSDP-FITIDAFQVVAGVLFLENII------------  1211

Query  539   GTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPA-IPLGIDVGGGLGPFTVFPD  597
                         PG     +TVSGQI            P  IPL +++     P+T+FP+
Sbjct  1212  -----------VPG-----LTVSGQI---------LVTPTPIPLTLNLD--TTPWTLFPN  1244

Query  598   GYSLPA---IPLGIDVGGGLGPFTVFPDGYSLPAIPLGID-VGGGLGPFTVFPDGYSLPA  653
             G+++PA   + +G++V      FT FP G + P    G+  +  GL  FT+ PDG++L  
Sbjct  1245  GFTIPAQTPVTVGMEVAND--GFTFFPGGLTFPRASAGVTGLSVGLDAFTLLPDGFTLDT  1302

Query  654   IPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGF  713
             +P   D    IG +  P I +P++P                      GFGN+TT PSSGF
Sbjct  1303  VPATFDGTILIGDIPIPIIDVPAVP----------------------GFGNTTTAPSSGF  1340

Query  714   FNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFGNTVSGLYNTS  770
             FN+G GG SGF NVG+G SG+WN   ++     SG  N G L+SG+LN G+ +SG YNTS
Sbjct  1341  FNTGGGGGSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTS  1400

Query  771   TLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNV  830
             TLG  T A  SG+GN   QL+GF+ N   GT+ N        +N+G A++G +N G GNV
Sbjct  1401  TLGAGTPAVVSGIGNLGQQLSGFLAN---GTVLN----RSPIVNIGWADVGAFNTGLGNV  1453

Query  831   GSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEA-LHNIGFGNIGGN  889
             G  N+G+ NIG  + G GN+GS N GFGN+G+ N+GFAN+GP +  A L N+G  N G N
Sbjct  1454  GDLNWGAANIGAQNLGLGNLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSN  1513

Query  890   NYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSG  949
             N+G AN+G GNIG  NTGTGNIGIGL GD Q G G LNSGSGNIG FNSG GN+GFFN+G
Sbjct  1514  NWGLANLGVGNIGLANTGTGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTG  1573

Query  950   NGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPG  1009
              GN G+ NSG++NTG+GN G  +TGLFN GN NTGI N GSYNTGS+N GDTNTG  NPG
Sbjct  1574  TGNFGLFNSGSFNTGIGNSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPG  1633

Query  1010  NANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLS  1069
             + NTG+ N G +NT     G  NTGAL+SG+ SNG+LWRGD++GL G S  ++IP  P+ 
Sbjct  1634  DINTGWFNTGIMNT-----GTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIR  1688

Query  1070  VEVNGGIGPIVVPDITIPGIPLSLNALGGVG-PIVVPDITIPGIPLSLNALGGVGPIVVP  1128
             +   GGIGPIV+PD TI   PL L   G       VPDI IP I + +N +  VG    P
Sbjct  1689  ITTTGGIGPIVIPDTTIL-PPLHLQITGDADYSFTVPDIPIPAIHIGINGVVTVG-FTAP  1746

Query  1129  DITIPGIPLSLNALGGVGPIVVPDITIP------GIPLSLNALGGVGPIVVPDITIPGIP  1182
             + T+     +  +    GPI   +I IP      G+P+     G +GPI +  I + GI 
Sbjct  1747  EATLLSALKNNGSFISFGPITRSNIDIPPMDFTLGLPVLGPITGQLGPIHLEPIVVAGIG  1806

Query  1183  LSLNALGGVGPITVPGVPISRIPL--TINIRIPVNITLNELPFNVAGIFTGYIGPIPLST  1240
             +         P+ +  +P+  I L  +I IRIPV+I  +     + GI    + PI  S 
Sbjct  1807  V---------PLEIEPIPLDAISLSESIPIRIPVDIPASV----IDGISMSEVVPIDASV  1853

Query  1241  FVLGVTLAGGTLESGIQGFSVNPFG--LNIPL  1270
              +  VT+ G T+ +   GF +      LNIP+
Sbjct  1854  DIPAVTITGTTISAIPLGFDIRTSAGPLNIPI  1885


 Score =  328 bits (842),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 303/704 (44%), Positives = 373/704 (53%), Gaps = 121/704 (17%)

Query  206   LGLANSGFGQMGAANLGILNLGSLN--PGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGN  263
             LG  N GFG +GA N+G  N G      G  N GL N GSNN GL N G GNIG  NTG 
Sbjct  1473  LGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTGT  1532

Query  264   GNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGN  323
             GNIG GL GD Q G GG NSG+GNIGLFNSGTGN+G  NTGTGNFG+ NSG S+NTGIGN
Sbjct  1533  GNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSG-SFNTGIGN  1591

Query  324   TGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGN  383
             +G  +TG FNAG  NTGI N G+YNTGSFN+G  NTG FN G  NTG+FN     TG+ N
Sbjct  1592  SGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWFN-----TGIMN  1646

Query  384   TGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-  442
             TG  NTG   SG  SNG  WRGD++GL G S  +TIP   + +   G +GPI IP  TI 
Sbjct  1647  TGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIRITTTGGIGPIVIPDTTIL  1706

Query  443   PEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL---ELSA  499
             P + L I  +G       VP I +PAI +GIN  G +      P  TL S         +
Sbjct  1707  PPLHLQI--TGDADYSFTVPDIPIPAIHIGIN--GVVTVGFTAPEATLLSALKNNGSFIS  1762

Query  500   FQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVT  559
             F  I   +I IP     +GL                        P + P           
Sbjct  1763  FGPITRSNIDIPPMDFTLGL------------------------PVLGP-----------  1787

Query  560   VSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTV  619
             ++GQ+GPI      +  P +  GI V     P  + P       IPL             
Sbjct  1788  ITGQLGPI------HLEPIVVAGIGV-----PLEIEP-------IPL-------------  1816

Query  620   FPDGYSL-PAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIP  678
               D  SL  +IP+ I V     P +V  DG S+  + + ID    I  +T    TI +IP
Sbjct  1817  --DAISLSESIPIRIPVDI---PASVI-DGISMSEV-VPIDASVDIPAVTITGTTISAIP  1869

Query  679   LGIDVSGSLGPINIPI-EIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNI  737
             LG D+  S GP+NIPI +I   PGFGNST  PSSGFFN+G GG SG GN+G+G SG  N 
Sbjct  1870  LGFDIRTSAGPLNIPIIDIPAAPGFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGLLNQ  1929

Query  738   AGN---LGN-SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGF  793
             AG    +G  SG  N G L SG+LN G  +SGL+N STL   T A  SG  N    ++G 
Sbjct  1930  AGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHMSGV  1989

Query  794   --------------------MRNAAGGTLFNF------GFANDGTLNLGNANLGDYNVGS  827
                                 + +AA   L +          N G +NLG AN+G++N+G+
Sbjct  1990  SIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFNLGA  2049

Query  828   GNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTG  871
             GNVG+ N G+GN+G  + G GN+G+ N GFGN+G+ N GF N G
Sbjct  2050  GNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAG  2093


 Score = 59.7 bits (143),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 54/125 (44%), Positives = 67/125 (54%), Gaps = 15/125 (12%)

Query  196   SSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGN  255
             S  G++A L+   A S F Q+   +  I  L  L+ G N   LGNVG  N+GL N G  N
Sbjct  1990  SIDGLIAILTFPPAESVFDQI--IDAAIAELQHLDIG-NALALGNVGGVNLGLANVGEFN  2046

Query  256   IGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGT  315
             +G GN GN N+G G            N G  N+GL N GTGN+G GN G GNFG GN+G 
Sbjct  2047  LGAGNVGNINVGAG------------NLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGL  2094

Query  316   SYNTG  320
             +   G
Sbjct  2095  TAGAG  2099


 Score = 58.9 bits (141),  Expect = 6e-06, Method: Compositional matrix adjust.
 Identities = 43/93 (47%), Positives = 55/93 (60%), Gaps = 1/93 (1%)

Query  189   VVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGL  248
             ++ AAI   + +    +L L N G   +G AN+G  NLG+ N G  N G GN+G +N+GL
Sbjct  2010  IIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGL  2069

Query  249   GNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGW  281
             GN G GN+GFGN G GN GFG  G    G G W
Sbjct  2070  GNVGTGNLGFGNIGAGNFGFGNAGL-TAGAGAW  2101


 Score = 58.2 bits (139),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 42/109 (39%), Positives = 61/109 (56%), Gaps = 1/109 (0%)

Query  155   HAGASAVASALTPFTAPP-QNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGF  213
             H    ++   +   T PP +++ D     A A    +      + G +  ++LGLAN G 
Sbjct  1985  HMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGE  2044

Query  214   GQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTG  262
               +GA N+G +N+G+ N GG+N GLGNVG+ N+G GN G GN GFGN G
Sbjct  2045  FNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAG  2093


 Score = 43.9 bits (102),  Expect = 0.25, Method: Compositional matrix adjust.
 Identities = 32/65 (50%), Positives = 38/65 (59%), Gaps = 0/65 (0%)

Query  965   LGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTG  1024
             LGNVG  N GL N G  N G GN G+ N G+ N G +N G  N G  N G+ N+G  N G
Sbjct  2029  LGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFG  2088

Query  1025  WGNIG  1029
             +GN G
Sbjct  2089  FGNAG  2093


 Score = 43.1 bits (100),  Expect = 0.35, Method: Compositional matrix adjust.
 Identities = 35/66 (54%), Positives = 38/66 (58%), Gaps = 5/66 (7%)

Query  924   GALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNT  983
             G +N G  N+G FN G GN+G     N NVG GN G  N GLGNVG  N G  N G  N 
Sbjct  2033  GGVNLGLANVGEFNLGAGNVG-----NINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNF  2087

Query  984   GIGNAG  989
             G GNAG
Sbjct  2088  GFGNAG  2093


 Score = 43.1 bits (100),  Expect = 0.45, Method: Compositional matrix adjust.
 Identities = 36/71 (51%), Positives = 41/71 (58%), Gaps = 5/71 (7%)

Query  931   GNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGS  990
             GN+G  N G  N+G FN G GNVG     N N G GN+G +N GL N G  N G GN G+
Sbjct  2030  GNVGGVNLGLANVGEFNLGAGNVG-----NINVGAGNLGGSNLGLGNVGTGNLGFGNIGA  2084

Query  991   YNTGSYNAGDT  1001
              N G  NAG T
Sbjct  2085  GNFGFGNAGLT  2095


 Score = 39.3 bits (90),  Expect = 5.5, Method: Compositional matrix adjust.
 Identities = 31/68 (46%), Positives = 40/68 (59%), Gaps = 1/68 (1%)

Query  967   NVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWG  1026
             ++GNA   L N G VN G+ N G +N G+ N G+ N G  N G +N G  N+G  N G+G
Sbjct  2022  DIGNA-LALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFG  2080

Query  1027  NIGDLNTG  1034
             NIG  N G
Sbjct  2081  NIGAGNFG  2088


>gi|308376082|ref|ZP_07446012.2| putative PPE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308344372|gb|EFP33223.1| putative PPE family protein [Mycobacterium tuberculosis SUMu007]
Length=1338

 Score =  800 bits (2066),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 690/1516 (46%), Positives = 842/1516 (56%), Gaps = 235/1516 (15%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             M+F  +PPEINS LI+ GAG  P+ AAA AWD+LA EL SAAA+F SVTSGLVG  W GP
Sbjct  1     MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGP  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             SS AMAAA APY GWL+AAAA A+ +A QA A+V  FEA  AA V P ++AANRS LVSL
Sbjct  61    SSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPA  180
               SN FGQN PAIAA E  YE MWA DV+ M  YH GASA A AL PF            
Sbjct  121   ALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPF------------  168

Query  181   QLAAAPAAVVTAAITSSKGVLANLSL---GLANSGFGQMGAANLGILNLGS---------  228
                 +P A + AA   +K +  NL L   GL N+G G +G+ N+G  N+GS         
Sbjct  169   ---GSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIG  225

Query  229   --------------------LNPGG---NNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGN  265
                                 L PG     N G GN GS N GL N G GNIGF NTG+GN
Sbjct  226   GNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGN  285

Query  266   IGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTG  325
              G GLTGDN  GFGG+N+G+GN+GLFNSGTGN+G  N+GTGN+G+ NSG SYNTGIGN+G
Sbjct  286   FGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSG-SYNTGIGNSG  344

Query  326   QANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTG  385
              A+TG FNAG  NTG+ N G+YNTGSFN G  NTG FN GS NTG+ N G++NTGV N+G
Sbjct  345   IASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSG  404

Query  386   NVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEI  445
             +VNTG F SGNYSNG FWRGDYQGL+GFS                   P  +P     ++
Sbjct  405   DVNTGAFISGNYSNGAFWRGDYQGLLGFS-----------------YRPAVLPQTPFLDL  447

Query  446   GLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINV  505
              L    +G L G + +P I +PAI                P  + N       A     V
Sbjct  448   TL----TGGL-GSVVIPAIDIPAIR---------------PEFSANV------AIDSFTV  481

Query  506   GSISIPASPLAIGLFGVNPTVGSIGPGSISI-QLGTPEIPAIPPFFPGFPPDYVTVSGQI  564
              SI IP   LA        T  S+G G I++  L  P +P    +  G  P       +I
Sbjct  482   PSIPIPQIDLA-------ATTVSVGLGPITVPHLDIPRVPVTLNYLFGSQPGGPL---KI  531

Query  565   GPITFLS----GGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVF  620
             GPIT L     G   L    + I      G  T F     L  +P    V          
Sbjct  532   GPITGLFNTPIGLTPLALSQIVIGASSSQGTITAF-----LANLPFSTPV----------  576

Query  621   PDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAI-PLGIDVGGAIGPLTTPPITIPSIPL  679
                 ++  IPL   + G   P  +FP G ++PA+ PL I++ G  G +T P ITI  IP 
Sbjct  577   ---VTIDEIPLLASITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPF  633

Query  680   GIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAG  739
              +    +LGP++I I++   PGFGN+T  PSSGFFNSG GG SGFGNVG+  SG WN A 
Sbjct  634   DLVAHSTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAP  693

Query  740   NL---GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRN  796
             +    G SG  N G L SG+LNFG+ +SGL+NTS LGL   A  SG+G+   QL+G + +
Sbjct  694   SALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLAS  753

Query  797   AAG---GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSN  853
                   G + NFG A+ G  N+G  N+GD+N+G+GNVG +N G GNIG  + G GN+G  
Sbjct  754   GTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWG  813

Query  854   NFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGI  913
             NFG GN G          PGL   L NIGFGN G  N+G AN+G GNIGF NTG+GN GI
Sbjct  814   NFGLGNSGLT--------PGLM-GLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGI  864

Query  914   GLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANT  973
             GLTGDN  GFG  N+GSGN+G FNSG GN+GFFNSG GN G+ NSG+YNTG+GN G A+T
Sbjct  865   GLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIAST  924

Query  974   GLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNT  1033
             GLFN G  NTG+ NAGSYNTGS+NAG  NTG  NPG+ NTG+LN GD NTG  N GD+NT
Sbjct  925   GLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNT  984

Query  1034  GALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL  1093
             GA ISG+YSNG  WRGDYQGL+G+S T +I                              
Sbjct  985   GAFISGNYSNGAFWRGDYQGLLGFSYTSTI------------------------------  1014

Query  1094  NALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVPDI  1153
                       +P+ T+  I    +A GG GPI+VP I  P IPL L+A G +G   +P +
Sbjct  1015  ----------IPEFTVANI----HASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPV  1060

Query  1154  TIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLT----IN  1209
             +I  I + ++ +  +GPI V DITIP + L       VGPI   G  I    LT    IN
Sbjct  1061  SISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFIN  1120

Query  1210  IRIPVNITL--NELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLN  1267
             + +P   T     LPF V            LS+  LGVT                     
Sbjct  1121  VNVPAIQTAPSEILPFTVL-----------LSS--LGVTHL-------------------  1148

Query  1268  IPLSGATNAVTIPGFAI--NPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTI  1325
                   T  +TIPGF I  +P  + +PLS    P   P   I    L + LSG T     
Sbjct  1149  ------TPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAF  1202

Query  1326  P-GFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFN-SGDGSASGFGNV  1383
             P   TI   P+ L  N  LGPIN  + I   PGFGN+T  PSSGFFN  G G  SGF N+
Sbjct  1203  PLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNL  1262

Query  1384  GPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVN  1443
             G G+SG+ N + + L G  SG  N G   SG+ N G  +SG  NT  +G +T+A  SG  
Sbjct  1263  GAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFG  1322

Query  1444  NIGQMLLGFFSPGAGP  1459
             N+GQ L G    G GP
Sbjct  1323  NVGQQLAGLIYTGTGP  1338


>gi|57117096|ref|YP_177964.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|313660340|ref|ZP_07817220.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
 gi|7478767|pir||E70969 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|38490361|emb|CAE55589.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|344221191|gb|AEN01822.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=3716

 Score =  800 bits (2065),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/1510 (45%), Positives = 846/1510 (57%), Gaps = 208/1510 (13%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             M F  LPPEINS L++ GAGS P+ AAA AWD LA EL SAA SF  VTSGL    W G 
Sbjct  1     MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGA  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             ++AAMAAA APY GWL + AA A+  A QA  +V  FEA  AA V PALVAANR+ LV+L
Sbjct  61    AAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVAL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLT----  176
               SN  GQN PAIAA EA YE MWA DV+ M+ YH+GASA A+AL  F+ P Q L     
Sbjct  121   AVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVG  180

Query  177   DLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNF  236
                  L A+PA  ++  + +  G + N ++GL N G   +GA N+G  NLG  N GG N 
Sbjct  181   AFLTALFASPAKALS--LNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNV  238

Query  237   GLGNVGSNNVGLGNT---------------------------GNGNIGFGNTGNGNIGFG  269
             G GN+G+ NVG GN+                           G GNIGFGNTG  N+G G
Sbjct  239   GFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVG  298

Query  270   LTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANT  329
             LTG++  G GG NSGTGNIGLFNSGTGN+G  N+GTGNFG+ NSG +YNTG+GN G A+T
Sbjct  299   LTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSG-NYNTGVGNAGTAST  357

Query  330   GFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNT  389
             G FNAG  NTG+ N G+YNTGSFN G  NTG FN G  NTG+ N GN NTG+ N+GNVNT
Sbjct  358   GLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNT  417

Query  390   GGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-PEIGLG  448
             G F SGN++NG  W GDYQGL G S   +IPA  + L   G +GPITI  I I P I L 
Sbjct  418   GAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLS  477

Query  449   INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITL--NSIGLELSAFQVINVG  506
             I+ +  L GP+ VP I +PA G GI     +   + I PITL      +    F   ++G
Sbjct  478   IHQTVNL-GPLVVPDIVIPAFGGGIGIPINIGP-LTITPITLFAQQTFVNQLPFPTFSLG  535

Query  507   SISIPASPLAIGLFGVN-PTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
              I+IP     I  F  N   V  IGP  I   +  P  P I                   
Sbjct  536   KITIPQ----IQTFDSNGQLVSFIGPIVIDTTIPGPTNPQID------------------  573

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
                 L+  +  P             P T+FP+G S P  PLG+ V       ++   G++
Sbjct  574   ----LTIRWDTP-------------PITLFPNGISAPDNPLGLLV-----SVSISNPGFT  611

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPA--IPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             +P                    G+S+PA  +PL ID+ G I   +TPPITI  IPL +  
Sbjct  612   IP--------------------GFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGG  651

Query  684   SGSLGPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  741
               ++GPI I  + I   PG GN+TT PSSGFFNSG GG SGFGNVG+G SG+WN A +  
Sbjct  652   GVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSAL  711

Query  742   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
                 SG  NVG L SG+LN G+ +SG YNTS L   T A  SG+GN   QL+G   +AAG
Sbjct  712   LGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGV--SAAG  769

Query  800   GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGN  859
              TL +    N     LG AN+G++N G GNVG  N G+ NIG  + G GN+G  N G GN
Sbjct  770   TTLRSMLAGN-----LGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGN  824

Query  860   VGSNNLGFANTGPGLTEA-LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGD  918
             +G  NLGFAN G     A + N+GFGN G NNYG AN+G GNIGF NTGTGNIGIGL GD
Sbjct  825   IGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGD  884

Query  919   NQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNT  978
             ++ G G LNSG GNIG FNSG GN+GFFNSG GN GIGNSG +NTG+GN G A+TGLFN 
Sbjct  885   HRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNA  944

Query  979   GNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALIS  1038
             G+ +TGI N G YNTGS+NAGDTNTG  NPG  NTG+ N G  NTG  N G   TGA ++
Sbjct  945   GSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMT  1004

Query  1039  GSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL-NALG  1097
             G YSNG+LWRG Y+GL+G     +I   P++V   GG+GP+ V  + +P + + + +A  
Sbjct  1005  GDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATV  1064

Query  1098  GVGPIVVPDITIPGIPL-----SLN-ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  1151
             G+GP  VP I+IP +P+     S++ A   + PI   D     I L L       P +  
Sbjct  1065  GLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITI  1124

Query  1152  DITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIR  1211
             D        +   + GV  + + +I +PG+ +S       G I V   P   IPLT+N+ 
Sbjct  1125  D--------AFQVVAGV--LFLENIIVPGLTVS-------GQILVTPTP---IPLTLNLD  1164

Query  1212  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGT-----LESGIQGFSVNPFGL  1266
                                      P + F  G T+   T     +E    GF+  P GL
Sbjct  1165  T-----------------------TPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGL  1201

Query  1267  NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIP  1326
               P + A   VT         GL+V L           F + P G  +     T P T  
Sbjct  1202  TFPRASA--GVT---------GLSVGLD---------AFTLLPDGFTLD----TVPATFD  1237

Query  1327  GFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPG  1386
             G  + G                  ++ + PGFGN+TT PSSGFFN+G G  SGF NVG G
Sbjct  1238  GTILIGDIPIPII-----------DVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAG  1286

Query  1387  ISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIG  1446
              SG WNQ  + L G  SG+ N G L+SGV N+G+ +SG+ NTST+G  T A  SG+ N+G
Sbjct  1287  TSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLG  1346

Query  1447  QMLLGFFSPG  1456
             Q L GF + G
Sbjct  1347  QQLSGFLANG  1356


 Score =  619 bits (1597),  Expect = 9e-175, Method: Compositional matrix adjust.
 Identities = 468/1044 (45%), Positives = 598/1044 (58%), Gaps = 125/1044 (11%)

Query  155   HAGASAVASALTPFTAPP-QNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGF  213
             H    ++   +   T PP +++ D     A A    +      + G +  ++LGLAN G 
Sbjct  1914  HMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGE  1973

Query  214   GQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGF---------------  258
               +GA N+G +N+G+ N GG+N GLGNVG+ N+G GN G GN GF               
Sbjct  1974  FNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNV  2033

Query  259   ----------------------GNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTG  296
                                    NTG GNIG GLTGD + G GG NSGTGN+GLFNSGTG
Sbjct  2034  GLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTG  2093

Query  297   NIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGS  356
             NIG  NTGTGNFG+ NSG SY+TG+GN G A+TG FNAG  NTG+ N G+YNTGS N+GS
Sbjct  2094  NIGFFNTGTGNFGLFNSG-SYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGS  2152

Query  357   FNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGT  416
             FNTG  N G+ NTG+FN G+ NTG+ NTGNVNTG FNSG+++NG  W GDY GL+GFS +
Sbjct  2153  FNTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFS  2212

Query  417   LTIPAAG-LDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             + I  +  LDLN   ++GPI I  I IP + L        +GP  +P + VPAI L I+ 
Sbjct  2213  IDIAGSTLLDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEIGPFTIPQVDVPAIPLEIHE  2272

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             +      I++ PI L       +  + I    + IPASP   G     P +     G   
Sbjct  2273  S------IHMDPIVLVPATTIPAQTRTI---PLDIPASP---GSTMTLPLISMRFEGEDW  2320

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVS-----GQIGPITFLSGGYSLPAIP-----LGIDV  585
             I   T  IP     FP  P   +T+      G  G +     G+ +P I      L +++
Sbjct  2321  ILGSTAAIPNFGDPFPA-PTQGITIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNI  2379

Query  586   GGGLGPFTVFPDGYSLP--AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFT  643
              GGL  FT+F  G ++P  AIPL ID  G L P T+FP GY++  +PL + +        
Sbjct  2380  SGGLPAFTLFAGGLTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALN-------  2432

Query  644   VFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFG  703
                                    LT P  +IP                  I++  TPGFG
Sbjct  2433  -----------------------LTVPDSSIPI-----------------IDVPPTPGFG  2452

Query  704   NSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFG  760
             N+T TPSSGFFNSG GG SGFGNVGS  SG+WN A +      SG LNVG L SG+LN G
Sbjct  2453  NTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGTLGSGVLNVG  2512

Query  761   NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANL  820
             + VSG+YNTS L L T A  SG+GN   QL+G    +A GT  N        LN+G A++
Sbjct  2513  SGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGV---SAAGTALN----QIPILNIGLADV  2565

Query  821   GDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEA-LH  879
             G++NVG GNVG  N G+ N+G  + G GN+G+ N GF NVG  N+GF N+G     A L 
Sbjct  2566  GNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLG  2625

Query  880   NIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSG  939
             N GFGN G  NYGFAN G  NIG  NTGTGNIGIGL GDN  G G LNSG+GNIG FNSG
Sbjct  2626  NTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSG  2685

Query  940   NGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAG  999
              GNIGFFNSG GN GIGNSG++NTG+GN G  +TGLFN G+ NTG+ NAGSYNTGS+NAG
Sbjct  2686  TGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNAG  2745

Query  1000  DTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSD  1059
             DTNTG  NPG  NTG+ N G  NTG  N G++ TGA +SG++SNG+LWRGD++GL     
Sbjct  2746  DTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGDHEGLFSLFY  2805

Query  1060  TLSIPAIPL-SVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNA  1118
             +L +P I +    ++GG GP+V+P I +P +   L     +G   +P I IP +  ++  
Sbjct  2806  SLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAHLTGNVAMGAFTIPQIDIPALTPNITG  2865

Query  1119  LGGVGPIVVPDITIPGIPLSLNAL  1142
                   IVV  + IP + + +  +
Sbjct  2866  SAAF-RIVVGSVRIPPVSVIVEQI  2888


 Score =  579 bits (1492),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 498/1126 (45%), Positives = 637/1126 (57%), Gaps = 192/1126 (17%)

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGN---  260
             L++GLA+ G   +G  N+G +NLG+ N G  N GLGNVG+ N+G  N G+GNIGFGN   
Sbjct  2558  LNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGL  2617

Query  261   ----------------------------------TGNGNIGFGLTGDNQQGFGGWNSGTG  286
                                               TG GNIG GL GDN  G GG NSG G
Sbjct  2618  TAGAAGLGNTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAG  2677

Query  287   NIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGN  346
             NIGLFNSGTGNIG  N+GTGNFGIGNSG S+NTGIGN+G  +TG FNAG  NTG+ N G+
Sbjct  2678  NIGLFNSGTGNIGFFNSGTGNFGIGNSG-SFNTGIGNSGTGSTGLFNAGSFNTGVANAGS  2736

Query  347   YNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGD  406
             YNTGSFN G  NTG FN G+ NTG+FN G+ NTG+ N+GNV TG F SGN+SNG  WRGD
Sbjct  2737  YNTGSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGD  2796

Query  407   YQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGL-------------GINSSG  453
             ++GL     +L +                  P ITI +  L                 + 
Sbjct  2797  HEGLFSLFYSLDV------------------PRITIVDAHLDGGFGPVVLPPIPVPAVNA  2838

Query  454   ALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPAS  513
              L G + +   T+P I              +IP +T N  G   +AF+++ VGS+ IP  
Sbjct  2839  HLTGNVAMGAFTIPQI--------------DIPALTPNITGS--AAFRIV-VGSVRIPPV  2881

Query  514   PLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG  573
              + +    +N +VG+             E+  I PF       +   +  +G ITF S G
Sbjct  2882  SVIVEQI-INASVGA-------------EM-RIDPF-----EMWTQGTNGLG-ITFYSFG  2920

Query  574   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGI  633
              S    P         GP  VF  G S  +    + +    G FT  P   + P I LG 
Sbjct  2921  -SADGSPYAT------GPL-VFGAGTSDGS---HLTISASSGAFTT-PQLETGP-ITLGF  2967

Query  634   DVGGGLGPFTVFPDGYSLPAIPL-GIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINI  692
              V G +   T+FP G + PA  L  +DV    G +  P IT P I    D S  +   +I
Sbjct  2968  QVPGSVNAITLFPGGLTFPATSLLNLDVTAGAGGVDIPAITWPEIAASADGSVYVLASSI  3027

Query  693   P-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLN  748
             P I I  TPG GNST TPSSGFFN+G GG SGFGN G+G SG+WN A        SGF N
Sbjct  3028  PLINIPPTPGIGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFAN  3087

Query  749   VGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFA  808
             VG L SG+LN G+ VSG+YNTSTLG+ T A  SG+GN   QL+G +   +GG+  N    
Sbjct  3088  VGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLL---SGGSAVN----  3140

Query  809   NDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFA  868
                 LN+G AN+G +N G GNVG  N G+ N+G  + GFGNIG+ N GFGN+G  N+G  
Sbjct  3141  PVTVLNIGLANVGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVG  3200

Query  869   NTGPGLTEA---LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGA  925
             N+G  LT     L N+G GN GGNN+G AN+G GNIG  NTGTGNIGIGLTGD Q G G 
Sbjct  3201  NSG--LTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGG  3258

Query  926   LNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGI  985
             LNSG+GN+G FNSG GN+GFFN+G GN G+ NSG++NTG+GN G  +TGLFN G+ NTG+
Sbjct  3259  LNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSGSFNTGVGNSGTGSTGLFNAGSFNTGV  3318

Query  986   GNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGI  1045
              NAGSYNTGS+N GDTNTG  NPG+ NTG+LN G+ NTG  N G++NTGA ++G++SNGI
Sbjct  3319  ANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANAGNVNTGAFVTGNFSNGI  3378

Query  1046  LWRGDYQGLIGYSDTLSIPAIP-LSVEVNGGIGPI-VVPDITIPGIPLSLNALGGVGPIV  1103
             LWRGDYQGL G++   ++P  P +  +V+GGIGPI V+P I IP IP+   A+GG+GPI 
Sbjct  3379  LWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIA  3438

Query  1104  VPDITIPGIPLSLNALGGVGPIVVPDITI-------------------------------  1132
             +PDI++P I L L+    VG I V  IT+                               
Sbjct  3439  IPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSGPTSEIWVKPSFF  3498

Query  1133  PGIPLSLNALGG---------VGPIVVPD--ITIPG--IPLSLNALGGVGPIVVPDITIP  1179
             PGI ++ ++ GG         VGPI +P   +T PG  IPL    +G    + +P  TIP
Sbjct  3499  PGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFTIPLDPIDIGLPVSLTIPGFTIP  3558

Query  1180  G------IPLSLNALGGVGPITVPGVPISRIPLTINIRI---PVNI  1216
             G      +PL L    G+ P+ +P + + RI L ++      P+N+
Sbjct  3559  GGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINV  3604


 Score =  562 bits (1448),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 546/1426 (39%), Positives = 696/1426 (49%), Gaps = 335/1426 (23%)

Query  209   ANSGFGQ---------------MGAANLGILNLGSLNPG---------------------  232
             AN G G                 G AN G L+ G LN G                     
Sbjct  1281  ANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVS  1340

Query  233   --GN---------------------NFGLGNVGSNNVGLGNTGN----------------  253
               GN                     N G  +VG+ N GLGN G+                
Sbjct  1341  GIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLG  1400

Query  254   ----GNIGFGNTGNGNIGF-----------------------------------------  268
                 GN+GFGN G GN+GF                                         
Sbjct  1401  NLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTG  1460

Query  269   ------GLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIG  322
                   GL GD Q G GG NSG+GNIGLFNSGTGN+G  NTGTGNFG+ NSG S+NTGIG
Sbjct  1461  TGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSG-SFNTGIG  1519

Query  323   NTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVG  382
             N+G  +TG FNAG  NTGI N G+YNTGSFN+G  NTG FN G  NTG+F     NTG+ 
Sbjct  1520  NSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWF-----NTGIM  1574

Query  383   NTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI  442
             NTG  NTG   SG  SNG  WRGD++GL G S  +TIP   + +   G +GPI IP  TI
Sbjct  1575  NTGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIRITTTGGIGPIVIPDTTI  1634

Query  443   -PEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL---ELS  498
              P + L I  +G       VP I +PAI +GIN  G +      P  TL S         
Sbjct  1635  LPPLHLQI--TGDADYSFTVPDIPIPAIHIGIN--GVVTVGFTAPEATLLSALKNNGSFI  1690

Query  499   AFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPA---IPPFFPGFPP  555
             +F  I + +I IP     +GL  + P  G +GP    I L  P + A   +P      P 
Sbjct  1691  SFGPITLSNIDIPPMDFTLGLPVLGPITGQLGP----IHL-EPIVVAGIGVPLEIEPIPL  1745

Query  556   DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSL-PAIPLGIDVGGGL  614
             D +++S  I PI           IP+ I       P +V  DG S+   +P+   V    
Sbjct  1746  DAISLSESI-PIR----------IPVDI-------PASVI-DGISMSEVVPIDASV----  1782

Query  615   GPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITI  674
                        +PA+ +                G ++ AIPLG D+  + GPL  P I I
Sbjct  1783  ----------DIPAVTI---------------TGTTISAIPLGFDIRTSAGPLNIPIIDI  1817

Query  675   PSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGF  734
             P+                       PGFGNST  PSSGFFN+G GG SG GN+G+G SG 
Sbjct  1818  PA----------------------APGFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGL  1855

Query  735   WNIAGN---LGN-SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQL  790
              N AG    +G  SG  N G L SG+LN G  +SGL+N STL   T A  SG  N    +
Sbjct  1856  LNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHM  1915

Query  791   AGF--------------------MRNAAGGTLFN------FGFANDGTLNLGNANLGDYN  824
             +G                     + +AA   L +          N G +NLG AN+G++N
Sbjct  1916  SGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFN  1975

Query  825   VGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFG  884
             +G+GNVG+ N G+GN+G  + G GN+G+ N GFGN+G+ N GF N G             
Sbjct  1976  LGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGL  2035

Query  885   NIGGN-NYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNI  943
                G+ ++G AN+G GNIG  NTGTGNIGIGLTGD + G G LNSG+GN+G FNSG GNI
Sbjct  2036  GNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNI  2095

Query  944   GFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNT  1003
             GFFN+G GN G+ NSG+Y+TG+GN G A+TGLFN GN NTG+ NAGSYNTGS N G  NT
Sbjct  2096  GFFNTGTGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGSFNT  2155

Query  1004  GDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI  1063
             G +NPG  NTG+ N G  NTG  N G++NTGA  SGS++NG LW GDY GL+G+S ++ I
Sbjct  2156  GGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFSIDI  2215

Query  1064  PAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL-SLNALGGV  1122
                 L                      L LN    +GPI +  I IPG+ L  ++ +  +
Sbjct  2216  AGSTL----------------------LDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEI  2253

Query  1123  GPIVVPDITIPGIPLSLNALGGVGPIV-VPDITIPG----IPLSLNALGGVGPIVVPDIT  1177
             GP  +P + +P IPL ++    + PIV VP  TIP     IPL + A  G        +T
Sbjct  2254  GPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRTIPLDIPASPG------STMT  2307

Query  1178  IPGIPLSLNA----LGGVGPITVPGVPISRIPLTINIRI-PVNITLNELPFNVAGIFTGY  1232
             +P I +        LG    I   G P       I I   P   T  EL  ++ G     
Sbjct  2308  LPLISMRFEGEDWILGSTAAIPNFGDPFPAPTQGITIHTGPGPGTTGELKISIPGF---E  2364

Query  1233  IGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVP  1292
             I  I  + F+L V ++G     G+  F++   GL IP    TNA+           L + 
Sbjct  2365  IPQIATTRFLLDVNISG-----GLPAFTLFAGGLTIP----TNAIP----------LTID  2405

Query  1293  LSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPI  1350
              SG   P+TI   G+ I+P  L++ L+     +T+P  +IP                  I
Sbjct  2406  ASGALDPITIFPGGYTIDPLPLHLALN-----LTVPDSSIP-----------------II  2443

Query  1351  NITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQ  1410
             ++   PGFGN+T TPSSGFFNSG G  SGFGNVG  +SG WNQ  +AL G  SG+ NVG 
Sbjct  2444  DVPPTPGFGNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGT  2503

Query  1411  LASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPG  1456
             L SGV N+G+ VSG  NTS +   T A  SG+ N+G  L G  + G
Sbjct  2504  LGSGVLNVGSGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGVSAAG  2549


 Score =  327 bits (838),  Expect = 1e-86, Method: Compositional matrix adjust.
 Identities = 274/627 (44%), Positives = 344/627 (55%), Gaps = 106/627 (16%)

Query  201   LANLSLGLANSGFGQMGAANLGILNLGSLN------------PGGNNFGLGNVGSNNVGL  248
             L   +LG  N GFG +GA NLG  N+G  N            PG  N GLGN G NN GL
Sbjct  3167  LGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGL  3226

Query  249   GNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNF  308
              N G GNIG  NTG GNIG GLTGD Q G GG NSG GN+GLFNSG GN+G  NTGTGNF
Sbjct  3227  ANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNF  3286

Query  309   GIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSN  368
             G+ NSG S+NTG+GN+G  +TG FNAG  NTG+ N G+YNTGSFN+G  NTG FN GS N
Sbjct  3287  GLFNSG-SFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSIN  3345

Query  369   TGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP---AAGLD  425
             TG+ N GN NTGV N GNVNTG F +GN+SNG  WRGDYQGL GF+   T+P   A G D
Sbjct  3346  TGWLNAGNANTGVANAGNVNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGAD  3405

Query  426   LNGLGSVGPITI-PSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPIN  484
             ++G   +GPIT+ P I IP I +G  + G  +GPI +P I+VP+I LG++     VG I 
Sbjct  3406  VSG--GIGPITVLPPIHIPPIPVGFAAVGG-IGPIAIPDISVPSIHLGLDPA-VHVGSIT  3461

Query  485   IPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIP  544
             + PIT+ +  + +S  Q    G+++  + P                         T EI 
Sbjct  3462  VNPITVRTPPVLVSYSQ----GAVTSTSGP-------------------------TSEIW  3492

Query  545   AIPPFFPGFPPDYVTVSGQ--------IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFP  596
               P FFPG      +  G         +GPI+  SG  + P                   
Sbjct  3493  VKPSFFPGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFP-------------------  3533

Query  597   DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPL  656
              G+++P  P  ID+G         P   ++P              FT+ P G  +P +PL
Sbjct  3534  -GFTIPLDP--IDIG--------LPVSLTIPG-------------FTI-PGGTLIPTLPL  3568

Query  657   GIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFG-NSTTTPSSGFFN  715
             G+ +   I P+  P I +  I L +    ++GPIN+PI   G      NSTT PSSGFFN
Sbjct  3569  GLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFN  3628

Query  716   SGTGGTSGFGNVGSGGSGFWNIAGN--LGN-SGFLNVGPLTSGILNFGNTVSGLYNTSTL  772
             +G GG SGF N G+G SG  N   +  LG+ SGF N G   SGILN G  +SG+YNT  L
Sbjct  3629  TGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGAL  3688

Query  773   GLATSAFHSGVGNTDSQLAGFMRNAAG  799
             G+ T+A  SG GN   QL+G +    G
Sbjct  3689  GVVTAAVVSGFGNVGQQLSGLLFTGVG  3715


 Score =  130 bits (326),  Expect = 3e-27, Method: Compositional matrix adjust.
 Identities = 135/344 (40%), Positives = 180/344 (53%), Gaps = 37/344 (10%)

Query  1131  TIPGIP-LSLNALGGVGPI-VVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNAL  1188
             T+P  P +  +  GG+GPI V+P I IP IP+   A+GG+GPI +PDI++P I L L+  
Sbjct  3395  TLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIAIPDISVPSIHLGLDPA  3454

Query  1189  GGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLA  1248
               VG ITV  + + R P       PV ++ ++         T  I   P  +F  G+ +A
Sbjct  3455  VHVGSITVNPITV-RTP-------PVLVSYSQGAVTSTSGPTSEIWVKP--SFFPGIRIA  3504

Query  1249  ---GGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAI--NPFGLNVPLSGGTSPVTIP  1303
                GG   S    + V P  ++IP    +  VT PGF I  +P  + +P+S     +TIP
Sbjct  3505  PSSGGGATSTQGAYFVGP--ISIP----SGTVTFPGFTIPLDPIDIGLPVS-----LTIP  3553

Query  1304  GFAINPFGLNVP-------LSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAP  1356
             GF I P G  +P       LS G  PV IP   +    L+L A+  +GPIN+PI      
Sbjct  3554  GFTI-PGGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGA  3612

Query  1357  GFG-NSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGV  1415
                 NSTT PSSGFFN+G G  SGF N G G+SGL N + + L G  SG  N G   SG+
Sbjct  3613  PGFGNSTTLPSSGFFNTGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGI  3672

Query  1416  ANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
              N G  +SG  NT  +G +TAA  SG  N+GQ L G    G GP
Sbjct  3673  LNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGLLFTGVGP  3716


 Score = 79.0 bits (193),  Expect = 6e-12, Method: Compositional matrix adjust.
 Identities = 88/199 (45%), Positives = 112/199 (57%), Gaps = 8/199 (4%)

Query  1265  GLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI-PGFAINPFG--LNVPLSGGTS  1321
             G ++ +S ++ A T P     P  L   + G  + +T+ PG    P    LN+ ++ G  
Sbjct  2941  GSHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATSLLNLDVTAGAG  3000

Query  1322  PVTIPGFTIPGSPLNLTANGGLGPI--NIP-INITSAPGFGNSTTTPSSGFFNSGDGSAS  1378
              V IP  T P   +  +A+G +  +  +IP INI   PG GNST TPSSGFFN+G G  S
Sbjct  3001  GVDIPAITWP--EIAASADGSVYVLASSIPLINIPPTPGIGNSTITPSSGFFNAGAGGGS  3058

Query  1379  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1438
             GFGN G G SG WNQ   AL G  SG  NVG L SGV NLG+ VSG  NTST+G  T A 
Sbjct  3059  GFGNFGAGTSGWWNQAHTALAGAGSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPAL  3118

Query  1439  NSGVNNIGQMLLGFFSPGA  1457
              SG+ N+G  L G  S G+
Sbjct  3119  VSGLGNVGHQLSGLLSGGS  3137


>gi|297733008|ref|ZP_06962126.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
Length=3725

 Score =  799 bits (2064),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/1510 (45%), Positives = 844/1510 (56%), Gaps = 208/1510 (13%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             M F  LPPEINS L++ GAGS P+ AAA AWD LA EL SAA SF  VTSGL    W G 
Sbjct  10    MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGA  69

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             ++AAMAAA APY GWL + AA A+  A QA  +V  FEA  AA V PALVAANR+ LV+L
Sbjct  70    AAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVAL  129

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLT----  176
               SN  GQN PAIAA EA YE MWA DV+ M+ YH+GASA A+AL  F+ P Q L     
Sbjct  130   AVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVG  189

Query  177   DLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNF  236
                  L A+PA  ++  + +  G + N ++GL N G   +GA N+G  NLG  N GG N 
Sbjct  190   AFLTALFASPAKALS--LNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNV  247

Query  237   GLGNVGSNNVGLGNT---------------------------GNGNIGFGNTGNGNIGFG  269
             G GN+G+ NVG GN+                           G GNIGFGNTG  N+G G
Sbjct  248   GFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVG  307

Query  270   LTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANT  329
             LTG++  G GG NSGTGNIGLFNSGTGN+G  N+GTGNFG+ NSG +YNTG+GN G A+T
Sbjct  308   LTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSG-NYNTGVGNAGTAST  366

Query  330   GFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNT  389
             G FNAG  NTG+ N G+YNTGSFN G  NTG FN G  NTG+ N GN NTG+ N+GNVNT
Sbjct  367   GLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNT  426

Query  390   GGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-PEIGLG  448
             G F SGN++NG  W GDYQGL G S   +IPA  + L   G +GPITI  I I P I L 
Sbjct  427   GAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLS  486

Query  449   INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITL--NSIGLELSAFQVINVG  506
             I+ +  L GP+ VP I +PA G GI     +   + I PITL      +    F   ++G
Sbjct  487   IHQTVNL-GPLVVPDIVIPAFGGGIGIPINIGP-LTITPITLFAQQTFVNQLPFPTFSLG  544

Query  507   SISIPASPLAIGLFGVN-PTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
              I+IP     I  F  N   V  IGP  I   +  P  P I                   
Sbjct  545   KITIPQ----IQTFDSNGQLVSFIGPIVIDTTIPGPTNPQID------------------  582

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
                 L+  +  P             P T+FP+G S P  PLG+ V       ++   G++
Sbjct  583   ----LTIRWDTP-------------PITLFPNGISAPDNPLGLLV-----SVSISNPGFT  620

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPA--IPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             +P                    G+S+PA  +PL ID+ G I   +TPPITI  IPL +  
Sbjct  621   IP--------------------GFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGG  660

Query  684   SGSLGPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  741
               ++GPI I  + I   PG GN+TT PSSGFFNSG GG SGFGNVG+G SG+WN A +  
Sbjct  661   GVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSAL  720

Query  742   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
                 SG  NVG L SG+LN G+ +SG YNTS L   T A  SG+GN   QL+G    +A 
Sbjct  721   LGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGV---SAA  777

Query  800   GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGN  859
             GT      A     NLG AN+G++N G GNVG  N G+ NIG  + G GN+G  N G GN
Sbjct  778   GTTLRSMLAG----NLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGN  833

Query  860   VGSNNLGFANTGPGLTEA-LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGD  918
             +G  NLGFAN G     A + N+GFGN G NNYG AN+G GNIGF NTGTGNIGIGL GD
Sbjct  834   IGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGD  893

Query  919   NQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNT  978
             ++ G G LNSG GNIG FNSG GN+GFFNSG GN GIGNSG +NTG+GN G A+TGLFN 
Sbjct  894   HRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNA  953

Query  979   GNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALIS  1038
             G+ +TGI N G YNTGS+NAGDTNTG  NPG  NTG+ N G  NTG  N G   TGA ++
Sbjct  954   GSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMT  1013

Query  1039  GSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL-NALG  1097
             G YSNG+LWRG Y+GL+G     +I   P++V   GG+GP+ V  + +P + + + +A  
Sbjct  1014  GDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATV  1073

Query  1098  GVGPIVVPDITIPGIPL-----SLN-ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  1151
             G+GP  VP I+IP +P+     S++ A   + PI   D     I L L       P +  
Sbjct  1074  GLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITI  1133

Query  1152  DITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIR  1211
             D        +   + GV  + + +I +PG+ +S       G I V   P   IPLT+N+ 
Sbjct  1134  D--------AFQVVAGV--LFLENIIVPGLTVS-------GQILVTPTP---IPLTLNLD  1173

Query  1212  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGT-----LESGIQGFSVNPFGL  1266
                                      P + F  G T+   T     +E    GF+  P GL
Sbjct  1174  T-----------------------TPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGL  1210

Query  1267  NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIP  1326
               P + A   VT         GL+V L           F + P G  +     T P T  
Sbjct  1211  TFPRASA--GVT---------GLSVGLD---------AFTLLPDGFTLD----TVPATFD  1246

Query  1327  GFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPG  1386
             G  + G                  ++ + PGFGN+TT PSSGFFN+G G  SGF NVG G
Sbjct  1247  GTILIGDIPIPII-----------DVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAG  1295

Query  1387  ISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIG  1446
              SG WNQ  + L G  SG+ N G L+SGV N+G+ +SG+ NTST+G  T A  SG+ N+G
Sbjct  1296  TSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLG  1355

Query  1447  QMLLGFFSPG  1456
             Q L GF + G
Sbjct  1356  QQLSGFLANG  1365


 Score =  619 bits (1597),  Expect = 1e-174, Method: Compositional matrix adjust.
 Identities = 468/1044 (45%), Positives = 598/1044 (58%), Gaps = 125/1044 (11%)

Query  155   HAGASAVASALTPFTAPP-QNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGF  213
             H    ++   +   T PP +++ D     A A    +      + G +  ++LGLAN G 
Sbjct  1923  HMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGE  1982

Query  214   GQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGF---------------  258
               +GA N+G +N+G+ N GG+N GLGNVG+ N+G GN G GN GF               
Sbjct  1983  FNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNV  2042

Query  259   ----------------------GNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTG  296
                                    NTG GNIG GLTGD + G GG NSGTGN+GLFNSGTG
Sbjct  2043  GLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTG  2102

Query  297   NIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGS  356
             NIG  NTGTGNFG+ NSG SY+TG+GN G A+TG FNAG  NTG+ N G+YNTGS N+GS
Sbjct  2103  NIGFFNTGTGNFGLFNSG-SYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGS  2161

Query  357   FNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGT  416
             FNTG  N G+ NTG+FN G+ NTG+ NTGNVNTG FNSG+++NG  W GDY GL+GFS +
Sbjct  2162  FNTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFS  2221

Query  417   LTIPAAG-LDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINS  475
             + I  +  LDLN   ++GPI I  I IP + L        +GP  +P + VPAI L I+ 
Sbjct  2222  IDIAGSTLLDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEIGPFTIPQVDVPAIPLEIHE  2281

Query  476   TGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSIS  535
             +      I++ PI L       +  + I    + IPASP   G     P +     G   
Sbjct  2282  S------IHMDPIVLVPATTIPAQTRTI---PLDIPASP---GSTMTLPLISMRFEGEDW  2329

Query  536   IQLGTPEIPAIPPFFPGFPPDYVTVS-----GQIGPITFLSGGYSLPAIP-----LGIDV  585
             I   T  IP     FP  P   +T+      G  G +     G+ +P I      L +++
Sbjct  2330  ILGSTAAIPNFGDPFPA-PTQGITIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNI  2388

Query  586   GGGLGPFTVFPDGYSLP--AIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFT  643
              GGL  FT+F  G ++P  AIPL ID  G L P T+FP GY++  +PL + +        
Sbjct  2389  SGGLPAFTLFAGGLTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALN-------  2441

Query  644   VFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFG  703
                                    LT P  +IP                  I++  TPGFG
Sbjct  2442  -----------------------LTVPDSSIPI-----------------IDVPPTPGFG  2461

Query  704   NSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLNVGPLTSGILNFG  760
             N+T TPSSGFFNSG GG SGFGNVGS  SG+WN A +      SG LNVG L SG+LN G
Sbjct  2462  NTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGTLGSGVLNVG  2521

Query  761   NTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANL  820
             + VSG+YNTS L L T A  SG+GN   QL+G    +A GT  N        LN+G A++
Sbjct  2522  SGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGV---SAAGTALN----QIPILNIGLADV  2574

Query  821   GDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEA-LH  879
             G++NVG GNVG  N G+ N+G  + G GN+G+ N GF NVG  N+GF N+G     A L 
Sbjct  2575  GNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLG  2634

Query  880   NIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSG  939
             N GFGN G  NYGFAN G  NIG  NTGTGNIGIGL GDN  G G LNSG+GNIG FNSG
Sbjct  2635  NTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSG  2694

Query  940   NGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAG  999
              GNIGFFNSG GN GIGNSG++NTG+GN G  +TGLFN G+ NTG+ NAGSYNTGS+NAG
Sbjct  2695  TGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNAG  2754

Query  1000  DTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSD  1059
             DTNTG  NPG  NTG+ N G  NTG  N G++ TGA +SG++SNG+LWRGD++GL     
Sbjct  2755  DTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGDHEGLFSLFY  2814

Query  1060  TLSIPAIPL-SVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNA  1118
             +L +P I +    ++GG GP+V+P I +P +   L     +G   +P I IP +  ++  
Sbjct  2815  SLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAHLTGNVAMGAFTIPQIDIPALTPNITG  2874

Query  1119  LGGVGPIVVPDITIPGIPLSLNAL  1142
                   IVV  + IP + + +  +
Sbjct  2875  SAAF-RIVVGSVRIPPVSVIVEQI  2897


 Score =  578 bits (1491),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 498/1126 (45%), Positives = 637/1126 (57%), Gaps = 192/1126 (17%)

Query  204   LSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGN---  260
             L++GLA+ G   +G  N+G +NLG+ N G  N GLGNVG+ N+G  N G+GNIGFGN   
Sbjct  2567  LNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGL  2626

Query  261   ----------------------------------TGNGNIGFGLTGDNQQGFGGWNSGTG  286
                                               TG GNIG GL GDN  G GG NSG G
Sbjct  2627  TAGAAGLGNTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAG  2686

Query  287   NIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGN  346
             NIGLFNSGTGNIG  N+GTGNFGIGNSG S+NTGIGN+G  +TG FNAG  NTG+ N G+
Sbjct  2687  NIGLFNSGTGNIGFFNSGTGNFGIGNSG-SFNTGIGNSGTGSTGLFNAGSFNTGVANAGS  2745

Query  347   YNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGD  406
             YNTGSFN G  NTG FN G+ NTG+FN G+ NTG+ N+GNV TG F SGN+SNG  WRGD
Sbjct  2746  YNTGSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGD  2805

Query  407   YQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGL-------------GINSSG  453
             ++GL     +L +                  P ITI +  L                 + 
Sbjct  2806  HEGLFSLFYSLDV------------------PRITIVDAHLDGGFGPVVLPPIPVPAVNA  2847

Query  454   ALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPAS  513
              L G + +   T+P I              +IP +T N  G   +AF+++ VGS+ IP  
Sbjct  2848  HLTGNVAMGAFTIPQI--------------DIPALTPNITGS--AAFRIV-VGSVRIPPV  2890

Query  514   PLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGG  573
              + +    +N +VG+             E+  I PF       +   +  +G ITF S G
Sbjct  2891  SVIVEQI-INASVGA-------------EM-RIDPF-----EMWTQGTNGLG-ITFYSFG  2929

Query  574   YSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGI  633
              S    P         GP  VF  G S  +    + +    G FT  P   + P I LG 
Sbjct  2930  -SADGSPYAT------GPL-VFGAGTSDGS---HLTISASSGAFTT-PQLETGP-ITLGF  2976

Query  634   DVGGGLGPFTVFPDGYSLPAIPL-GIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINI  692
              V G +   T+FP G + PA  L  +DV    G +  P IT P I    D S  +   +I
Sbjct  2977  QVPGSVNAITLFPGGLTFPATSLLNLDVTAGAGGVDIPAITWPEIAASADGSVYVLASSI  3036

Query  693   P-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL---GNSGFLN  748
             P I I  TPG GNST TPSSGFFN+G GG SGFGN G+G SG+WN A        SGF N
Sbjct  3037  PLINIPPTPGIGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFAN  3096

Query  749   VGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFA  808
             VG L SG+LN G+ VSG+YNTSTLG+ T A  SG+GN   QL+G +   +GG+  N    
Sbjct  3097  VGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLL---SGGSAVN----  3149

Query  809   NDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFA  868
                 LN+G AN+G +N G GNVG  N G+ N+G  + GFGNIG+ N GFGN+G  N+G  
Sbjct  3150  PVTVLNIGLANVGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVG  3209

Query  869   NTGPGLTEA---LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGA  925
             N+G  LT     L N+G GN GGNN+G AN+G GNIG  NTGTGNIGIGLTGD Q G G 
Sbjct  3210  NSG--LTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGG  3267

Query  926   LNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGI  985
             LNSG+GN+G FNSG GN+GFFN+G GN G+ NSG++NTG+GN G  +TGLFN G+ NTG+
Sbjct  3268  LNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSGSFNTGVGNSGTGSTGLFNAGSFNTGV  3327

Query  986   GNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGI  1045
              NAGSYNTGS+N GDTNTG  NPG+ NTG+LN G+ NTG  N G++NTGA ++G++SNGI
Sbjct  3328  ANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANAGNVNTGAFVTGNFSNGI  3387

Query  1046  LWRGDYQGLIGYSDTLSIPAIP-LSVEVNGGIGPI-VVPDITIPGIPLSLNALGGVGPIV  1103
             LWRGDYQGL G++   ++P  P +  +V+GGIGPI V+P I IP IP+   A+GG+GPI 
Sbjct  3388  LWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIA  3447

Query  1104  VPDITIPGIPLSLNALGGVGPIVVPDITI-------------------------------  1132
             +PDI++P I L L+    VG I V  IT+                               
Sbjct  3448  IPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSGPTSEIWVKPSFF  3507

Query  1133  PGIPLSLNALGG---------VGPIVVPD--ITIPG--IPLSLNALGGVGPIVVPDITIP  1179
             PGI ++ ++ GG         VGPI +P   +T PG  IPL    +G    + +P  TIP
Sbjct  3508  PGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFTIPLDPIDIGLPVSLTIPGFTIP  3567

Query  1180  G------IPLSLNALGGVGPITVPGVPISRIPLTINIRI---PVNI  1216
             G      +PL L    G+ P+ +P + + RI L ++      P+N+
Sbjct  3568  GGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINV  3613


 Score =  561 bits (1447),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 546/1426 (39%), Positives = 696/1426 (49%), Gaps = 335/1426 (23%)

Query  209   ANSGFGQ---------------MGAANLGILNLGSLNPG---------------------  232
             AN G G                 G AN G L+ G LN G                     
Sbjct  1290  ANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVS  1349

Query  233   --GN---------------------NFGLGNVGSNNVGLGNTGN----------------  253
               GN                     N G  +VG+ N GLGN G+                
Sbjct  1350  GIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLG  1409

Query  254   ----GNIGFGNTGNGNIGF-----------------------------------------  268
                 GN+GFGN G GN+GF                                         
Sbjct  1410  NLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTG  1469

Query  269   ------GLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIG  322
                   GL GD Q G GG NSG+GNIGLFNSGTGN+G  NTGTGNFG+ NSG S+NTGIG
Sbjct  1470  TGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSG-SFNTGIG  1528

Query  323   NTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVG  382
             N+G  +TG FNAG  NTGI N G+YNTGSFN+G  NTG FN G  NTG+F     NTG+ 
Sbjct  1529  NSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWF-----NTGIM  1583

Query  383   NTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI  442
             NTG  NTG   SG  SNG  WRGD++GL G S  +TIP   + +   G +GPI IP  TI
Sbjct  1584  NTGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIRITTTGGIGPIVIPDTTI  1643

Query  443   -PEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGL---ELS  498
              P + L I  +G       VP I +PAI +GIN  G +      P  TL S         
Sbjct  1644  LPPLHLQI--TGDADYSFTVPDIPIPAIHIGIN--GVVTVGFTAPEATLLSALKNNGSFI  1699

Query  499   AFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPA---IPPFFPGFPP  555
             +F  I + +I IP     +GL  + P  G +GP    I L  P + A   +P      P 
Sbjct  1700  SFGPITLSNIDIPPMDFTLGLPVLGPITGQLGP----IHL-EPIVVAGIGVPLEIEPIPL  1754

Query  556   DYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSL-PAIPLGIDVGGGL  614
             D +++S  I PI           IP+ I       P +V  DG S+   +P+   V    
Sbjct  1755  DAISLSESI-PIR----------IPVDI-------PASVI-DGISMSEVVPIDASV----  1791

Query  615   GPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITI  674
                        +PA+ +                G ++ AIPLG D+  + GPL  P I I
Sbjct  1792  ----------DIPAVTI---------------TGTTISAIPLGFDIRTSAGPLNIPIIDI  1826

Query  675   PSIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGF  734
             P+                       PGFGNST  PSSGFFN+G GG SG GN+G+G SG 
Sbjct  1827  PA----------------------APGFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGL  1864

Query  735   WNIAGN---LGN-SGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQL  790
              N AG    +G  SG  N G L SG+LN G  +SGL+N STL   T A  SG  N    +
Sbjct  1865  LNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHM  1924

Query  791   AGF--------------------MRNAAGGTLFN------FGFANDGTLNLGNANLGDYN  824
             +G                     + +AA   L +          N G +NLG AN+G++N
Sbjct  1925  SGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFN  1984

Query  825   VGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFG  884
             +G+GNVG+ N G+GN+G  + G GN+G+ N GFGN+G+ N GF N G             
Sbjct  1985  LGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGL  2044

Query  885   NIGGN-NYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNI  943
                G+ ++G AN+G GNIG  NTGTGNIGIGLTGD + G G LNSG+GN+G FNSG GNI
Sbjct  2045  GNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNI  2104

Query  944   GFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNT  1003
             GFFN+G GN G+ NSG+Y+TG+GN G A+TGLFN GN NTG+ NAGSYNTGS N G  NT
Sbjct  2105  GFFNTGTGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGSFNT  2164

Query  1004  GDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSI  1063
             G +NPG  NTG+ N G  NTG  N G++NTGA  SGS++NG LW GDY GL+G+S ++ I
Sbjct  2165  GGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFSIDI  2224

Query  1064  PAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPL-SLNALGGV  1122
                 L                      L LN    +GPI +  I IPG+ L  ++ +  +
Sbjct  2225  AGSTL----------------------LDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEI  2262

Query  1123  GPIVVPDITIPGIPLSLNALGGVGPIV-VPDITIPG----IPLSLNALGGVGPIVVPDIT  1177
             GP  +P + +P IPL ++    + PIV VP  TIP     IPL + A  G        +T
Sbjct  2263  GPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRTIPLDIPASPG------STMT  2316

Query  1178  IPGIPLSLNA----LGGVGPITVPGVPISRIPLTINIRI-PVNITLNELPFNVAGIFTGY  1232
             +P I +        LG    I   G P       I I   P   T  EL  ++ G     
Sbjct  2317  LPLISMRFEGEDWILGSTAAIPNFGDPFPAPTQGITIHTGPGPGTTGELKISIPGF---E  2373

Query  1233  IGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVP  1292
             I  I  + F+L V ++G     G+  F++   GL IP    TNA+           L + 
Sbjct  2374  IPQIATTRFLLDVNISG-----GLPAFTLFAGGLTIP----TNAIP----------LTID  2414

Query  1293  LSGGTSPVTI--PGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPI  1350
              SG   P+TI   G+ I+P  L++ L+     +T+P  +IP                  I
Sbjct  2415  ASGALDPITIFPGGYTIDPLPLHLALN-----LTVPDSSIP-----------------II  2452

Query  1351  NITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQ  1410
             ++   PGFGN+T TPSSGFFNSG G  SGFGNVG  +SG WNQ  +AL G  SG+ NVG 
Sbjct  2453  DVPPTPGFGNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGT  2512

Query  1411  LASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPG  1456
             L SGV N+G+ VSG  NTS +   T A  SG+ N+G  L G  + G
Sbjct  2513  LGSGVLNVGSGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGVSAAG  2558


 Score =  327 bits (837),  Expect = 1e-86, Method: Compositional matrix adjust.
 Identities = 274/627 (44%), Positives = 344/627 (55%), Gaps = 106/627 (16%)

Query  201   LANLSLGLANSGFGQMGAANLGILNLGSLN------------PGGNNFGLGNVGSNNVGL  248
             L   +LG  N GFG +GA NLG  N+G  N            PG  N GLGN G NN GL
Sbjct  3176  LGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGL  3235

Query  249   GNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNF  308
              N G GNIG  NTG GNIG GLTGD Q G GG NSG GN+GLFNSG GN+G  NTGTGNF
Sbjct  3236  ANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNF  3295

Query  309   GIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSN  368
             G+ NSG S+NTG+GN+G  +TG FNAG  NTG+ N G+YNTGSFN+G  NTG FN GS N
Sbjct  3296  GLFNSG-SFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSIN  3354

Query  369   TGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIP---AAGLD  425
             TG+ N GN NTGV N GNVNTG F +GN+SNG  WRGDYQGL GF+   T+P   A G D
Sbjct  3355  TGWLNAGNANTGVANAGNVNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGAD  3414

Query  426   LNGLGSVGPITI-PSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPIN  484
             ++G   +GPIT+ P I IP I +G  + G  +GPI +P I+VP+I LG++     VG I 
Sbjct  3415  VSG--GIGPITVLPPIHIPPIPVGFAAVGG-IGPIAIPDISVPSIHLGLDPA-VHVGSIT  3470

Query  485   IPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIP  544
             + PIT+ +  + +S  Q    G+++  + P                         T EI 
Sbjct  3471  VNPITVRTPPVLVSYSQ----GAVTSTSGP-------------------------TSEIW  3501

Query  545   AIPPFFPGFPPDYVTVSGQ--------IGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFP  596
               P FFPG      +  G         +GPI+  SG  + P                   
Sbjct  3502  VKPSFFPGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFP-------------------  3542

Query  597   DGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPL  656
              G+++P  P  ID+G         P   ++P              FT+ P G  +P +PL
Sbjct  3543  -GFTIPLDP--IDIG--------LPVSLTIPG-------------FTI-PGGTLIPTLPL  3577

Query  657   GIDVGGAIGPLTTPPITIPSIPLGIDVSGSLGPINIPIEIAGTPGFG-NSTTTPSSGFFN  715
             G+ +   I P+  P I +  I L +    ++GPIN+PI   G      NSTT PSSGFFN
Sbjct  3578  GLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFN  3637

Query  716   SGTGGTSGFGNVGSGGSGFWNIAGN--LGN-SGFLNVGPLTSGILNFGNTVSGLYNTSTL  772
             +G GG SGF N G+G SG  N   +  LG+ SGF N G   SGILN G  +SG+YNT  L
Sbjct  3638  TGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGAL  3697

Query  773   GLATSAFHSGVGNTDSQLAGFMRNAAG  799
             G+ T+A  SG GN   QL+G +    G
Sbjct  3698  GVVTAAVVSGFGNVGQQLSGLLFTGVG  3724


 Score =  130 bits (326),  Expect = 3e-27, Method: Compositional matrix adjust.
 Identities = 135/344 (40%), Positives = 180/344 (53%), Gaps = 37/344 (10%)

Query  1131  TIPGIP-LSLNALGGVGPI-VVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNAL  1188
             T+P  P +  +  GG+GPI V+P I IP IP+   A+GG+GPI +PDI++P I L L+  
Sbjct  3404  TLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIAIPDISVPSIHLGLDPA  3463

Query  1189  GGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLA  1248
               VG ITV  + + R P       PV ++ ++         T  I   P  +F  G+ +A
Sbjct  3464  VHVGSITVNPITV-RTP-------PVLVSYSQGAVTSTSGPTSEIWVKP--SFFPGIRIA  3513

Query  1249  ---GGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAI--NPFGLNVPLSGGTSPVTIP  1303
                GG   S    + V P  ++IP    +  VT PGF I  +P  + +P+S     +TIP
Sbjct  3514  PSSGGGATSTQGAYFVGP--ISIP----SGTVTFPGFTIPLDPIDIGLPVS-----LTIP  3562

Query  1304  GFAINPFGLNVP-------LSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAP  1356
             GF I P G  +P       LS G  PV IP   +    L+L A+  +GPIN+PI      
Sbjct  3563  GFTI-PGGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGA  3621

Query  1357  GFG-NSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGV  1415
                 NSTT PSSGFFN+G G  SGF N G G+SGL N + + L G  SG  N G   SG+
Sbjct  3622  PGFGNSTTLPSSGFFNTGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGI  3681

Query  1416  ANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP  1459
              N G  +SG  NT  +G +TAA  SG  N+GQ L G    G GP
Sbjct  3682  LNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGLLFTGVGP  3725


 Score = 79.0 bits (193),  Expect = 6e-12, Method: Compositional matrix adjust.
 Identities = 88/199 (45%), Positives = 112/199 (57%), Gaps = 8/199 (4%)

Query  1265  GLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTI-PGFAINPFG--LNVPLSGGTS  1321
             G ++ +S ++ A T P     P  L   + G  + +T+ PG    P    LN+ ++ G  
Sbjct  2950  GSHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATSLLNLDVTAGAG  3009

Query  1322  PVTIPGFTIPGSPLNLTANGGLGPI--NIP-INITSAPGFGNSTTTPSSGFFNSGDGSAS  1378
              V IP  T P   +  +A+G +  +  +IP INI   PG GNST TPSSGFFN+G G  S
Sbjct  3010  GVDIPAITWP--EIAASADGSVYVLASSIPLINIPPTPGIGNSTITPSSGFFNAGAGGGS  3067

Query  1379  GFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAF  1438
             GFGN G G SG WNQ   AL G  SG  NVG L SGV NLG+ VSG  NTST+G  T A 
Sbjct  3068  GFGNFGAGTSGWWNQAHTALAGAGSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPAL  3127

Query  1439  NSGVNNIGQMLLGFFSPGA  1457
              SG+ N+G  L G  S G+
Sbjct  3128  VSGLGNVGHQLSGLLSGGS  3146


>gi|297636010|ref|ZP_06953790.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=3716

 Score =  799 bits (2064),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/1510 (45%), Positives = 846/1510 (57%), Gaps = 208/1510 (13%)

Query  1     MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGP  60
             M F  LPPEINS L++ GAGS P+ AAA AWD LA EL SAA SF  VTSGL    W G 
Sbjct  1     MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGA  60

Query  61    SSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSL  120
             ++AAMAAA APY GWL + AA A+  A QA  +V  FEA  AA V PALVAANR+ LV+L
Sbjct  61    AAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVAL  120

Query  121   VFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLT----  176
               SN  GQN PAIAA EA YE MWA DV+ M+ YH+GASA A+AL  F+ P Q L     
Sbjct  121   AVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVG  180

Query  177   DLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNF  236
                  L A+PA  ++  + +  G + N ++GL N G   +GA N+G  NLG  N GG N 
Sbjct  181   AFLTALFASPAKALS--LNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNV  238

Query  237   GLGNVGSNNVGLGNT---------------------------GNGNIGFGNTGNGNIGFG  269
             G GN+G+ NVG GN+                           G GNIGFGNTG  N+G G
Sbjct  239   GFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVG  298

Query  270   LTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANT  329
             LTG++  G GG NSGTGNIGLFNSGTGN+G  N+GTGNFG+ NSG +YNTG+GN G A+T
Sbjct  299   LTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSG-NYNTGVGNAGTAST  357

Query  330   GFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNT  389
             G FNAG  NTG+ N G+YNTGSFN G  NTG FN G  NTG+ N GN NTG+ N+GNVNT
Sbjct  358   GLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNT  417

Query  390   GGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITI-PEIGLG  448
             G F SGN++NG  W GDYQGL G S   +IPA  + L   G +GPITI  I I P I L 
Sbjct  418   GAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLS  477

Query  449   INSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITL--NSIGLELSAFQVINVG  506
             I+ +  L GP+ VP I +PA G GI     +   + I PITL      +    F   ++G
Sbjct  478   IHQTVNL-GPLVVPDIVIPAFGGGIGIPINIGP-LTITPITLFAQQTFVNQLPFPTFSLG  535

Query  507   SISIPASPLAIGLFGVN-PTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIG  565
              I+IP     I  F  N   V  IGP  I   +  P  P I                   
Sbjct  536   KITIPQ----IQTFDSNGQLVSFIGPIVIDTTIPGPTNPQID------------------  573

Query  566   PITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYS  625
                 L+  +  P             P T+FP+G S P  PLG+ V       ++   G++
Sbjct  574   ----LTIRWDTP-------------PITLFPNGISAPDNPLGLLV-----SVSISNPGFT  611

Query  626   LPAIPLGIDVGGGLGPFTVFPDGYSLPA--IPLGIDVGGAIGPLTTPPITIPSIPLGIDV  683
             +P                    G+S+PA  +PL ID+ G I   +TPPITI  IPL +  
Sbjct  612   IP--------------------GFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGG  651

Query  684   SGSLGPINIP-IEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNL-  741
               ++GPI I  + I   PG GN+TT PSSGFFNSG GG SGFGNVG+G SG+WN A +  
Sbjct  652   GVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSAL  711

Query  742   --GNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAG  799
                 SG  NVG L SG+LN G+ +SG YNTS L   T A  SG+GN   QL+G   +AAG
Sbjct  712   LGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGV--SAAG  769

Query  800   GTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGN  859
              TL +    N     LG AN+G++N G GNVG  N G+ NIG  + G GN+G  N G GN
Sbjct  770   TTLRSMLAGN-----LGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGN  824

Query  860   VGSNNLGFANTGPGLTEA-LHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGD  918
             +G  NLGFAN G     A + N+GFGN G NNYG AN+G GNIGF NTGTGNIGIGL GD
Sbjct  825   IGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGD  884

Query  919   NQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNT  978
             ++ G G LNSG GNIG FNSG GN+GFFNSG GN GIGNSG +NTG+GN G A+TGLFN 
Sbjct  885   HRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNA  944

Query  979   GNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALIS  1038
             G+ +TGI N G YNTGS+NAGDTNTG  NPG  NTG+ N G  NTG  N G   TGA ++
Sbjct  945   GSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMT  1004

Query  1039  GSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSL-NALG  1097
             G YSNG+LWRG Y+GL+G     +I   P++V   GG+GP+ V  + +P + + + +A  
Sbjct  1005  GDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATV  1064

Query  1098  GVGPIVVPDITIPGIPL-----SLN-ALGGVGPIVVPDITIPGIPLSLNALGGVGPIVVP  1151
             G+GP  VP I+IP +P+     S++ A   + PI   D     I L L       P +  
Sbjct  1065  GLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITI  1124

Query  1152  DITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIR  1211
             D        +   + GV  + + +I +PG+ +S       G I V   P   IPLT+N+ 
Sbjct  1125  D--------AFQVVAGV--LFLENIIVPGLTVS-------GQILVTPTP---IPLTLNLD  1164

Query  1212  IPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGT-----LESGIQGFSVNPFGL  1266
                                      P + F  G T+   T     +E    GF+  P GL
Sbjct  1165  T-----------------------TPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGL  1201

Query  1267  NIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLNVPLSGGTSPVTIP  1326
               P + A   VT         GL+V L           F + P G  +     T P T  
Sbjct  1202  TFPRASA--GVT---------GLSVGLD---------AFTLLPDGFTLD----TVPATFD  1237

Query  1327  GFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPG  1386
             G  + G                  ++ + PGFGN+TT PSSGFFN+G G  SGF NVG G
Sbjct  1238  GTILIGDIPIPII-----------DVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAG  1286

Query  1387  ISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIG  1446
              SG WNQ  + L G  SG+ N G L+SGV N+G+ +SG+ NTST+G  T A  SG+ N+G
Sbjct  1287  TSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLG  1346

Query  1447  QMLLGFFSPG  1456
             Q L GF + G
Sbjct  1347  QQLSGFLANG  1356



Lambda     K      H
   0.315    0.140    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 3774005316604


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40