BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1938 Length=356 Score E Sequences producing significant alignments: (Bits) Value gi|161760896|pdb|2E3J|A Chain A, The Crystal Structure Of Epoxid... 726 0.0 gi|171848969|pdb|2ZJF|A Chain A, Crystal Structure Of Mycobacter... 725 0.0 gi|15609075|ref|NP_216454.1| epoxide hydrolase EphB [Mycobacteri... 724 0.0 gi|289574621|ref|ZP_06454848.1| epoxide hydrolase ephB [Mycobact... 723 0.0 gi|289746124|ref|ZP_06505502.1| epoxide hydrolase ephB [Mycobact... 721 0.0 gi|340626948|ref|YP_004745400.1| putative epoxide hydrolase EPHB... 718 0.0 gi|183982870|ref|YP_001851161.1| epoxide hydrolase EphB [Mycobac... 627 6e-178 gi|118618306|ref|YP_906638.1| epoxide hydrolase EphB [Mycobacter... 619 2e-175 gi|120404956|ref|YP_954785.1| alpha/beta hydrolase fold protein ... 618 6e-175 gi|120404952|ref|YP_954781.1| alpha/beta hydrolase fold protein ... 501 7e-140 gi|289570023|ref|ZP_06450250.1| epoxide hydrolase ephB [Mycobact... 369 5e-100 gi|326331387|ref|ZP_08197677.1| epoxide hydrolase [Nocardioidace... 303 2e-80 gi|257055882|ref|YP_003133714.1| putative hydrolase or acyltrans... 278 9e-73 gi|345008742|ref|YP_004811096.1| alpha/beta hydrolase fold conta... 276 5e-72 gi|21221992|ref|NP_627771.1| epoxide hydrolase [Streptomyces coe... 275 9e-72 gi|289770815|ref|ZP_06530193.1| epoxide hydrolase [Streptomyces ... 274 2e-71 gi|297190003|ref|ZP_06907401.1| epoxide hydrolase [Streptomyces ... 273 2e-71 gi|294633670|ref|ZP_06712228.1| epoxide hydrolase [Streptomyces ... 271 1e-70 gi|302562686|ref|ZP_07315028.1| epoxide hydrolase [Streptomyces ... 271 2e-70 gi|345003172|ref|YP_004806026.1| alpha/beta hydrolase fold prote... 270 4e-70 gi|297154269|gb|ADI03981.1| epoxide hydrolase [Streptomyces bing... 269 6e-70 gi|329937243|ref|ZP_08286842.1| epoxide hydrolase [Streptomyces ... 269 6e-70 gi|312197969|ref|YP_004018030.1| alpha/beta hydrolase fold prote... 267 2e-69 gi|326781325|ref|ZP_08240590.1| Soluble epoxide hydrolase [Strep... 266 3e-69 gi|182440651|ref|YP_001828370.1| putative epoxide hydrolase [Str... 266 4e-69 gi|291452892|ref|ZP_06592282.1| epoxide hydrolase [Streptomyces ... 263 3e-68 gi|254381781|ref|ZP_04997145.1| epoxide hydrolase [Streptomyces ... 256 4e-66 gi|344997863|ref|YP_004800717.1| alpha/beta hydrolase fold prote... 255 8e-66 gi|295835404|ref|ZP_06822337.1| epoxide hydrolase [Streptomyces ... 255 8e-66 gi|119477846|ref|ZP_01617969.1| putative epoxide hydrolase [mari... 254 2e-65 gi|29828647|ref|NP_823281.1| epoxide hydrolase [Streptomyces ave... 254 2e-65 gi|297199344|ref|ZP_06916741.1| epoxide hydrolase [Streptomyces ... 253 4e-65 gi|302523212|ref|ZP_07275554.1| epoxide hydrolase [Streptomyces ... 251 1e-64 gi|337762851|emb|CCB71559.1| putative epoxide hydrolase [Strepto... 248 9e-64 gi|333022985|ref|ZP_08451049.1| putative epoxide hydrolase [Stre... 246 5e-63 gi|318061383|ref|ZP_07980104.1| epoxide hydrolase [Streptomyces ... 244 2e-62 gi|320008071|gb|ADW02921.1| alpha/beta hydrolase fold protein [S... 243 4e-62 gi|29830353|ref|NP_824987.1| epoxide hydrolase [Streptomyces ave... 234 2e-59 gi|284045280|ref|YP_003395620.1| alpha/beta hydrolase fold prote... 231 1e-58 gi|326386649|ref|ZP_08208271.1| epoxide hydrolase [Novosphingobi... 223 4e-56 gi|302552187|ref|ZP_07304529.1| epoxide hydrolase [Streptomyces ... 223 6e-56 gi|108762454|ref|YP_629896.1| putative epoxide hydrolase [Myxoco... 219 8e-55 gi|294632870|ref|ZP_06711429.1| epoxide hydrolase [Streptomyces ... 218 1e-54 gi|297200409|ref|ZP_06917806.1| epoxide hydrolase [Streptomyces ... 218 2e-54 gi|27376225|ref|NP_767754.1| epoxide hydrolase [Bradyrhizobium j... 217 2e-54 gi|197104586|ref|YP_002129963.1| epoxide hydrolase [Phenylobacte... 215 1e-53 gi|150018674|ref|YP_001310928.1| alpha/beta hydrolase fold prote... 214 1e-53 gi|269125887|ref|YP_003299257.1| alpha/beta hydrolase fold prote... 214 2e-53 gi|345010956|ref|YP_004813310.1| alpha/beta hydrolase fold conta... 213 5e-53 gi|320108864|ref|YP_004184454.1| alpha/beta hydrolase fold prote... 212 6e-53 >gi|161760896|pdb|2E3J|A Chain A, The Crystal Structure Of Epoxide Hydrolase B (Rv1938) From Mycobacterium Tuberculosis At 2.1 Angstrom Length=356 Score = 726 bits (1873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/356 (100%), Positives = 356/356 (100%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 >gi|171848969|pdb|2ZJF|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Epoxide Hydrolase B Complexed With An Inhibitor Length=362 Score = 725 bits (1872), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/356 (100%), Positives = 356/356 (100%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 7 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 66 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 67 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 126 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 127 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 186 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 187 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 246 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 247 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 306 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 307 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 362 >gi|15609075|ref|NP_216454.1| epoxide hydrolase EphB [Mycobacterium tuberculosis H37Rv] gi|15841409|ref|NP_336446.1| epoxide hydrolase [Mycobacterium tuberculosis CDC1551] gi|31793130|ref|NP_855623.1| epoxide hydrolase EphB [Mycobacterium bovis AF2122/97] 66 more sequence titles Length=356 Score = 724 bits (1870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/356 (99%), Positives = 356/356 (100%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 >gi|289574621|ref|ZP_06454848.1| epoxide hydrolase ephB [Mycobacterium tuberculosis K85] gi|289539052|gb|EFD43630.1| epoxide hydrolase ephB [Mycobacterium tuberculosis K85] Length=356 Score = 723 bits (1866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/356 (99%), Positives = 356/356 (100%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVG+VVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGNVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 >gi|289746124|ref|ZP_06505502.1| epoxide hydrolase ephB [Mycobacterium tuberculosis 02_1987] gi|289758047|ref|ZP_06517425.1| epoxide hydrolase EphB [Mycobacterium tuberculosis T85] gi|294996857|ref|ZP_06802548.1| epoxide hydrolase ephB [Mycobacterium tuberculosis 210] gi|289686652|gb|EFD54140.1| epoxide hydrolase ephB [Mycobacterium tuberculosis 02_1987] gi|289713611|gb|EFD77623.1| epoxide hydrolase EphB [Mycobacterium tuberculosis T85] gi|326903544|gb|EGE50477.1| epoxide hydrolase ephB [Mycobacterium tuberculosis W-148] gi|339294871|gb|AEJ46982.1| epoxide hydrolase ephB [Mycobacterium tuberculosis CCDC5079] gi|339298495|gb|AEJ50605.1| epoxide hydrolase ephB [Mycobacterium tuberculosis CCDC5180] Length=356 Score = 721 bits (1862), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/356 (99%), Positives = 355/356 (99%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELA PGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAWPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 >gi|340626948|ref|YP_004745400.1| putative epoxide hydrolase EPHB [Mycobacterium canettii CIPT 140010059] gi|340005138|emb|CCC44287.1| putative epoxide hydrolase EPHB (epoxide hydratase) [Mycobacterium canettii CIPT 140010059] Length=356 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/356 (99%), Positives = 355/356 (99%), Gaps = 0/356 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +S+VHRIL+CRGTRIHAVAD PPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 MSRVHRILDCRGTRIHAVADGPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVG+LDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGILDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY Sbjct 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ Sbjct 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP Sbjct 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP 356 >gi|183982870|ref|YP_001851161.1| epoxide hydrolase EphB [Mycobacterium marinum M] gi|54289553|gb|AAV32086.1| putative epoxide hydrolase [Mycobacterium marinum] gi|183176196|gb|ACC41306.1| epoxide hydrolase EphB [Mycobacterium marinum M] Length=352 Score = 627 bits (1618), Expect = 6e-178, Method: Compositional matrix adjust. Identities = 308/355 (87%), Positives = 335/355 (95%), Gaps = 4/355 (1%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 ++Q HRILNCRGTRIHAV D +GPLV+LLHGFPESWYSWRHQIPALA AGYRVVA+ Sbjct 1 MAQAHRILNCRGTRIHAVEDG----EGPLVILLHGFPESWYSWRHQIPALAAAGYRVVAV 56 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDV+G++D+YGA++AFV+GHDWGAPVAWTFAWL+P R Sbjct 57 DQRGYGRSSKYRVQKAYRIKELVGDVLGLVDAYGADKAFVIGHDWGAPVAWTFAWLYPQR 116 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGE RP+DYHLELAG GRVWYQDYF+ QDGII EIEE Sbjct 117 CAGVVGISVPFAGRGVIGLPGSPFGEHRPNDYHLELAGEGRVWYQDYFSAQDGIIAEIEE 176 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 D+R WLLGLTYTVSG+GM+AATKAA DAGVDL SMDPIDVIRAGPLCMA+GARLKDAFVY Sbjct 177 DVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRAGPLCMADGARLKDAFVY 236 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFT+ADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQ+GKPL+ PALFIGGQ Sbjct 237 PETMPAWFTDADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQEGKPLSAPALFIGGQ 296 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 YDVGT WGA+AI RAHEVM +YRGTHM+ADVGHWIQQEAP+ETNRLLL+FLGGLR Sbjct 297 YDVGTTWGAEAIARAHEVMSDYRGTHMVADVGHWIQQEAPDETNRLLLEFLGGLR 351 >gi|118618306|ref|YP_906638.1| epoxide hydrolase EphB [Mycobacterium ulcerans Agy99] gi|118570416|gb|ABL05167.1| epoxide hydrolase EphB [Mycobacterium ulcerans Agy99] Length=351 Score = 619 bits (1596), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 307/355 (87%), Positives = 333/355 (94%), Gaps = 5/355 (1%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 ++Q HRILNCRGTRIHAV D +GPLV+LLHGFPESWYSWRHQIPALA A YRVVA+ Sbjct 1 MAQAHRILNCRGTRIHAVEDG----EGPLVILLHGFPESWYSWRHQIPALAAADYRVVAV 56 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDV+GV+D+YGA++AFV+GHDWGAPVAWTFAWL+P R Sbjct 57 DQRGYGRSSKYRVQKAYRIKELVGDVLGVVDAYGADKAFVIGHDWGAPVAWTFAWLYPQR 116 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGE RP+DYHLELAG GRVWYQD F+ QDGII EIEE Sbjct 117 CAGVVGISVPFAGRGVIGLPGSPFGEHRPNDYHLELAGEGRVWYQD-FSAQDGIIAEIEE 175 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 D+R WLLGLTYTVSG+GM+AATKAA DAGVDL SMDPIDVIRAGPLCMA+GARLKDAFVY Sbjct 176 DVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRAGPLCMADGARLKDAFVY 235 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMPAWFT+ADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQ+GKPL+ PALFIGGQ Sbjct 236 PETMPAWFTDADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQEGKPLSAPALFIGGQ 295 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 YDVGT WGA+AI RAHEVM +YRGTHM+ADVGHWIQQEAP+ETNRLLL+FLGGLR Sbjct 296 YDVGTTWGAEAIARAHEVMSDYRGTHMVADVGHWIQQEAPDETNRLLLEFLGGLR 350 >gi|120404956|ref|YP_954785.1| alpha/beta hydrolase fold protein [Mycobacterium vanbaalenii PYR-1] gi|119957774|gb|ABM14779.1| epoxide hydrolase, Serine peptidase, MEROPS family S33 [Mycobacterium vanbaalenii PYR-1] Length=351 Score = 618 bits (1593), Expect = 6e-175, Method: Compositional matrix adjust. Identities = 308/354 (88%), Positives = 326/354 (93%), Gaps = 4/354 (1%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +SQ+HR+LNCRGTRIHAV + +GPLVVL+HGFPESWYSWRHQIPALA AGYRVVAI Sbjct 1 MSQIHRMLNCRGTRIHAVEEG----EGPLVVLIHGFPESWYSWRHQIPALAAAGYRVVAI 56 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGD+VGV+D+YG E+A VVGHDWGAPVAWTFAWLHP R Sbjct 57 DQRGYGRSSKYRVQKAYRIKELVGDIVGVIDAYGVERAVVVGHDWGAPVAWTFAWLHPQR 116 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGV GISVPFAGRGVIGLPGSPFGE RP DYHLELAGPGRVWYQDYF+ QDGII EIEE Sbjct 117 CAGVAGISVPFAGRGVIGLPGSPFGEHRPDDYHLELAGPGRVWYQDYFSAQDGIIAEIEE 176 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 DLRGWL GLTYTVSG+GM+AATKAAV AGVDLESMDPIDVIRAGPLCMAEGARLKDAF Y Sbjct 177 DLRGWLWGLTYTVSGDGMIAATKAAVAAGVDLESMDPIDVIRAGPLCMAEGARLKDAFSY 236 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PETMP WFTE DLDFYT EFERSGFGGPLSFYHNIDNDWHDLA+Q G PLTPPA+FIGGQ Sbjct 237 PETMPDWFTEDDLDFYTAEFERSGFGGPLSFYHNIDNDWHDLAEQAGTPLTPPAVFIGGQ 296 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 YDVGT WGA+A+ERA EVMPNY GTHM+ DVGHWIQQEAPEETNRLLLDFL GL Sbjct 297 YDVGTTWGAEALERAPEVMPNYCGTHMVPDVGHWIQQEAPEETNRLLLDFLRGL 350 >gi|120404952|ref|YP_954781.1| alpha/beta hydrolase fold protein [Mycobacterium vanbaalenii PYR-1] gi|119957770|gb|ABM14775.1| alpha/beta hydrolase fold protein [Mycobacterium vanbaalenii PYR-1] Length=344 Score = 501 bits (1290), Expect = 7e-140, Method: Compositional matrix adjust. Identities = 240/352 (69%), Positives = 279/352 (80%), Gaps = 9/352 (2%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 +HR ++C GTRIHAV GPLV+LLHGFPESWYSWRHQIPALA AGYRVVAIDQR Sbjct 2 IHRNIDCNGTRIHAVEQG----SGPLVILLHGFPESWYSWRHQIPALANAGYRVVAIDQR 57 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 G+GRSSK+RV AYRI +V DV ++D++G EQA V+GHDWGAPVAWTFAWLHP RC G Sbjct 58 GFGRSSKFRVNDAYRIDRVVADVEALIDAFGEEQAVVIGHDWGAPVAWTFAWLHPQRCRG 117 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 VVG+SVPFAGRG+IGLPG PFGE RP DYH+ELAGPGR +YQDYF+ QDGI+ EIEEDLR Sbjct 118 VVGVSVPFAGRGLIGLPGCPFGETRPRDYHIELAGPGRTFYQDYFSAQDGILYEIEEDLR 177 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 W LGLTYTVSG+ + AA A + DP++ +R GPLCM EGARL DAFV+PE+ Sbjct 178 KWFLGLTYTVSGDAVAAAI-----ADGHVPPADPVEALRYGPLCMVEGARLDDAFVWPES 232 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 MP WFTE DLDFY EFERSGF G L+FYHN+D W L + +PLTPPA+FIGG+YD+ Sbjct 233 MPQWFTEDDLDFYVNEFERSGFAGGLAFYHNVDAGWEVLDGVENQPLTPPAMFIGGEYDI 292 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T WGA+AI RA E M +YRG+H+IA GHWIQQE P ETNRLLL+FLG L+ Sbjct 293 ATTWGAEAIARADEKMSDYRGSHLIAGAGHWIQQERPAETNRLLLEFLGQLQ 344 >gi|289570023|ref|ZP_06450250.1| epoxide hydrolase ephB [Mycobacterium tuberculosis T17] gi|289543777|gb|EFD47425.1| epoxide hydrolase ephB [Mycobacterium tuberculosis T17] Length=189 Score = 369 bits (946), Expect = 5e-100, Method: Compositional matrix adjust. Identities = 181/184 (99%), Positives = 183/184 (99%), Gaps = 0/184 (0%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 +SQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI Sbjct 1 MSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR Sbjct 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE Sbjct 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 Query 181 DLRG 184 D+ G Sbjct 181 DVAG 184 >gi|326331387|ref|ZP_08197677.1| epoxide hydrolase [Nocardioidaceae bacterium Broad-1] gi|325950643|gb|EGD42693.1| epoxide hydrolase [Nocardioidaceae bacterium Broad-1] Length=333 Score = 303 bits (777), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 166/348 (48%), Positives = 205/348 (59%), Gaps = 28/348 (8%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 H N G +H V PPD GPLV+L+HGFPESWYSWRHQI ALA AGYR VAID R Sbjct 7 THHTENVNGIDLHWVESGPPD--GPLVLLVHGFPESWYSWRHQIAALADAGYRTVAIDVR 64 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYG SSK + YR+ VGD VG++ + GA A +VGHDWGAP+AWT A L PD Sbjct 65 GYGGSSKPDAIEDYRMLRHVGDNVGLVHALGARTATIVGHDWGAPIAWTSAQLRPDVFTA 124 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V G+SVPF SP G RRP++ + G +Y YF + EI D+R Sbjct 125 VAGLSVPF----------SPSGRRRPTEAMAQAGGDDEDFYISYFQTPGVVEAEILPDVR 174 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 WLLG+ Y++SG+G++AA + R + G RL D FVYP Sbjct 175 SWLLGIYYSISGDGVLAAGRGP----------------RGALGLVPRGHRLSDQFVYPVE 218 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 MP W TEAD+DFY GEF S F GPL+ Y NID DW DLA P+T P+LF+ G+YD Sbjct 219 MPEWLTEADVDFYAGEFADSDFFGPLARYRNIDRDWEDLAAFSDVPITVPSLFVAGEYDG 278 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFL 351 I G + IER +P + ++ GHW+QQE PEETN+LLL+FL Sbjct 279 PAITGRRQIERFDTTLPGLTRSVVLPRCGHWVQQERPEETNQLLLEFL 326 >gi|257055882|ref|YP_003133714.1| putative hydrolase or acyltransferase of alpha/beta superfamily [Saccharomonospora viridis DSM 43017] gi|256585754|gb|ACU96887.1| predicted hydrolase or acyltransferase of alpha/beta superfamily [Saccharomonospora viridis DSM 43017] Length=350 Score = 278 bits (711), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 151/353 (43%), Positives = 207/353 (59%), Gaps = 8/353 (2%) Query 3 QVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQ 62 + R + G R H +GPLV+LLHGFPESW+SW HQIP +A AGYR VA D Sbjct 1 MLQRTVTANGQRFHYAEQG----EGPLVLLLHGFPESWHSWSHQIPMIAEAGYRAVAPDL 56 Query 63 RGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCA 122 RGYGRSSK R YRI ELV D VG++++ G +A VVGHDWG+ +AWT AW PD Sbjct 57 RGYGRSSKPRRVDDYRITELVADCVGLVEALGETEAVVVGHDWGSMLAWTAAWTRPDVFR 116 Query 123 GVVGISVPFAGRGVIGLPG-SPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEED 181 GVVG+SV F GRG++ + G S GE RPS+ H +AGP + +YQ+ + +G+ E EED Sbjct 117 GVVGLSVAFGGRGLLPVAGVSSLGELRPSEVHRVIAGPDKAFYQEIWIDGEGLAAEAEED 176 Query 182 LRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYP 241 + + ++ SG+ A + + E + ++ RA + G+R + V P Sbjct 177 MYTFFRDQFHSFSGDVYPADHQPPNVLTISPEEV--LEFTRASGAVVDRGSRFRSGLVSP 234 Query 242 ETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQY 301 ET+P W DLDFY E+ER+G L++Y +D DW LA +G+P+ PA+FIG Sbjct 235 ETLPEWLAR-DLDFYVAEYERTGLHHALNWYRCMDLDWELLAPYEGRPIEVPAMFIGSDL 293 Query 302 DVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 DV T+WGA+AI +P T ++ GHWI +EAP T ++ FL L Sbjct 294 DVATLWGAEAIANFPTTVPRLTETVILERCGHWITREAPVATGEAIVRFLRTL 346 >gi|345008742|ref|YP_004811096.1| alpha/beta hydrolase fold containing protein [Streptomyces violaceusniger Tu 4113] gi|344035091|gb|AEM80816.1| alpha/beta hydrolase fold containing protein [Streptomyces violaceusniger Tu 4113] Length=328 Score = 276 bits (705), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 156/351 (45%), Positives = 201/351 (58%), Gaps = 35/351 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR ++ RIH V GPLV+L+HGFPESWYSWRHQ+PALA AGYRV A+D R Sbjct 10 THRPVSSPAGRIHVVEQG----TGPLVLLVHGFPESWYSWRHQLPALAAAGYRVAAVDVR 65 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ AYR++ELV D V V+++ G E A V+GHDWG+P+A A L PD Sbjct 66 GYGRSSRPGAVDAYRMRELVADNVAVVEALGEESAVVIGHDWGSPIAANSALLRPDVFRA 125 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+ SP G RPS+ + G +Y YF EIE D+R Sbjct 126 VGMLSVPY----------SPSGGPRPSEVFAGMGGE-EEFYVSYFQEPGRAEAEIEPDVR 174 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G+ +SG+ M G DL P + GA +++ F + Sbjct 175 GWLAGIYAALSGDTM---------PGPDLPD----------PHFITRGATMRERFPA-DR 214 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +PAW +E DLD Y GEFER+G G L+ Y N+D DW +LA+ G P+T P+LFIGG D Sbjct 215 LPAWLSEQDLDAYAGEFERTGLSGALNRYRNMDRDWEELAEFNGAPITQPSLFIGGALDA 274 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W AI+ +P G+H++ GHWIQQE PEE NRLL+D+L L Sbjct 275 STTWMGDAIKAYPTTLPGLVGSHILDGCGHWIQQERPEEINRLLVDWLNSL 325 >gi|21221992|ref|NP_627771.1| epoxide hydrolase [Streptomyces coelicolor A3(2)] gi|5139628|emb|CAB45554.1| putative epoxide hydrolase [Streptomyces coelicolor A3(2)] Length=354 Score = 275 bits (703), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 158/356 (45%), Positives = 203/356 (58%), Gaps = 38/356 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 VHR++ RIH V GPLV+L+HGFPESWYSWRHQ+PALA AG+R VA+D R Sbjct 30 VHRLVPSPAGRIHLVEQG----SGPLVLLVHGFPESWYSWRHQLPALAAAGFRAVALDVR 85 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ +AYR+ +LV D V V+++ G A VVGHDWGA +A A L PD Sbjct 86 GYGRSSRPDAVEAYRMLDLVADNVAVVEALGESSAVVVGHDWGANIAAHSALLRPDVFRA 145 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGP-----GRVWYQDYFAVQDGIITEI 178 V +SVP+ +P G RPS+ ++ P G+ +Y YF EI Sbjct 146 VGLLSVPY----------TPPGGPRPSEAFAGMSDPAGPFAGQEFYVSYFQEPGRAEAEI 195 Query 179 EEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAF 238 E D+RGWL GL AA+ AG DP P +A G R++D F Sbjct 196 EPDVRGWLAGL-------------YAALSAGTMPGPQDP------DPHFVAPGGRMRDRF 236 Query 239 VYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIG 298 +P+W TE DLD Y GEFER+G G L+ Y N+D DW DLA +G P+T P+LF+G Sbjct 237 PSAGRLPSWLTEEDLDVYAGEFERTGLTGALNRYRNMDRDWADLAAHEGAPITQPSLFLG 296 Query 299 GQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 G D T W + AIE +P +H++ GHW+QQE PEETNRLL ++L GL Sbjct 297 GALDASTTWLSDAIEAYPVTLPGLSASHLLDGCGHWLQQERPEETNRLLTEWLTGL 352 >gi|289770815|ref|ZP_06530193.1| epoxide hydrolase [Streptomyces lividans TK24] gi|289701014|gb|EFD68443.1| epoxide hydrolase [Streptomyces lividans TK24] Length=325 Score = 274 bits (700), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 157/356 (45%), Positives = 203/356 (58%), Gaps = 38/356 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 +HR++ RIH V GPLV+L+HGFPESWYSWRHQ+PALA AG+R VA+D R Sbjct 1 MHRLVPSPAGRIHLVEQG----SGPLVLLVHGFPESWYSWRHQLPALAAAGFRAVALDVR 56 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ +AYR+ +LV D V V+++ G A VVGHDWGA +A A L PD Sbjct 57 GYGRSSRPDAVEAYRMLDLVADNVAVVEALGESSAVVVGHDWGANIAAHSALLRPDVFRA 116 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGP-----GRVWYQDYFAVQDGIITEI 178 V +SVP+ +P G RPS+ ++ P G+ +Y YF EI Sbjct 117 VGLLSVPY----------TPPGGPRPSEAFAGMSDPAGPFAGQEFYVSYFQEPGRAEAEI 166 Query 179 EEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAF 238 E D+RGWL GL AA+ AG DP P +A G R++D F Sbjct 167 EPDVRGWLAGL-------------YAALSAGTMPGPQDP------DPHFVAPGGRMRDRF 207 Query 239 VYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIG 298 +P+W TE DLD Y GEFER+G G L+ Y N+D DW DLA +G P+T P+LF+G Sbjct 208 PSAGRLPSWLTEEDLDVYAGEFERTGLTGALNRYRNMDRDWADLAAHEGAPITQPSLFLG 267 Query 299 GQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 G D T W + AIE +P +H++ GHW+QQE PEETNRLL ++L GL Sbjct 268 GALDASTTWLSDAIEAYPVTLPGLSASHLLDGCGHWLQQERPEETNRLLTEWLTGL 323 >gi|297190003|ref|ZP_06907401.1| epoxide hydrolase [Streptomyces pristinaespiralis ATCC 25486] gi|297150333|gb|EDY62570.2| epoxide hydrolase [Streptomyces pristinaespiralis ATCC 25486] Length=342 Score = 273 bits (699), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 156/350 (45%), Positives = 194/350 (56%), Gaps = 34/350 (9%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR + R+H V GPLV+L+HGFPESWYSWR Q+PALA AGYR VAID RG Sbjct 25 HRTVEAPAGRLHLVEQG----TGPLVLLVHGFPESWYSWRRQLPALAAAGYRAVAIDVRG 80 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSSK AYR+ +LV D V V+ + G E A +VGHDWG+ +A A LHP+ V Sbjct 81 YGRSSKPAATDAYRMLDLVEDNVAVVRALGEESAVIVGHDWGSTIAAASALLHPEIVRAV 140 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 +SVP+A PG P RPSD + GP + +Y YF TEIE D+R Sbjct 141 GLLSVPYAP------PGGP----RPSDVFGRIGGPEQEFYVSYFQEPGRAETEIEPDVRS 190 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G +S + M A + P +A G RL+D F + Sbjct 191 WLAGFYAALSADTMPAHDE-------------------PDPHFVAPGCRLRDHFPA-GPL 230 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 PAW TE DLD Y GEFER+G G L+ Y N+D DW DLA G P+T PALFIGG D Sbjct 231 PAWLTEDDLDVYAGEFERTGLTGALNRYRNMDRDWEDLAPHHGAPITQPALFIGGALDAS 290 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W A AI+ +P +H++ GHW+QQE P+E N LL D+L + Sbjct 291 TTWMADAIDAYSTTLPALSASHLLDGCGHWVQQERPDEVNSLLTDWLASV 340 >gi|294633670|ref|ZP_06712228.1| epoxide hydrolase [Streptomyces sp. e14] gi|292830312|gb|EFF88663.1| epoxide hydrolase [Streptomyces sp. e14] Length=328 Score = 271 bits (693), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 154/351 (44%), Positives = 198/351 (57%), Gaps = 34/351 (9%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR + R+H V GPLV+L+HGFPESWYSWR Q+PALA AGYR VAID RG Sbjct 11 HRTVQGPAGRLHLVEQG----TGPLVLLVHGFPESWYSWRRQLPALASAGYRAVAIDVRG 66 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRS+K AYR+ +LV D V V+ + G E A VVGHDWG+ +A A LHP+ V Sbjct 67 YGRSAKPEATDAYRMLDLVEDNVAVVRALGEESAVVVGHDWGSNIAAASALLHPEVFRAV 126 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 +SVP+A PG P RP+D ++ GP + +Y YF EIE D+RG Sbjct 127 GLLSVPYAP------PGGP----RPTDVFGQIGGPEQEFYVSYFQEPGRAEAEIEPDVRG 176 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G +S + M A + P +A G RL+D F + Sbjct 177 WLAGFYAALSADTMPAQGE-------------------PDPHFVARGGRLRDRFPA-GVL 216 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 PAW +E DLD Y GEFER+G G L+ Y N+D DW DLA +G P+ P+LFIGG D Sbjct 217 PAWLSEDDLDVYAGEFERTGITGALNRYRNMDRDWEDLAPYRGAPIEQPSLFIGGALDAS 276 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W + AI+ +P H++ GHW+QQE P+E NRLL+D+LG L+ Sbjct 277 TTWMSDAIDAYPTTLPGLSACHLLDGCGHWVQQERPDEVNRLLIDWLGALQ 327 >gi|302562686|ref|ZP_07315028.1| epoxide hydrolase [Streptomyces griseoflavus Tu4000] gi|302480304|gb|EFL43397.1| epoxide hydrolase [Streptomyces griseoflavus Tu4000] Length=344 Score = 271 bits (692), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 153/351 (44%), Positives = 192/351 (55%), Gaps = 34/351 (9%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR + R+H GPLV+L+HGFPESWYSWR Q+PALA AGYR VAID RG Sbjct 27 HRTIETPAGRLHLAVQG----TGPLVLLVHGFPESWYSWRRQLPALAAAGYRAVAIDVRG 82 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSSK AYR+ +LV D V V+ + G E A +VGHDWG+ +A A LHP V Sbjct 83 YGRSSKPAATDAYRMLDLVEDNVAVVRALGEESAVIVGHDWGSNIAAASALLHPGVFRAV 142 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 +SVP+A P G RP+D + GP + +Y YF EIE D+RG Sbjct 143 GLLSVPYA----------PPGGPRPTDVFGRIGGPEQEFYVSYFQQPGRAEAEIEPDVRG 192 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G +SG+ M A + P A G RL+D F + Sbjct 193 WLTGFYAALSGDTMPAEGE-------------------PDPHFAARGGRLRDRFPA-GPL 232 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 PAW +E DLD Y GEFER+G G L+ Y N+D DW DLA +G P+T PALF+GG D Sbjct 233 PAWLSEEDLDVYAGEFERTGLTGALNRYRNMDRDWEDLAPHRGAPITQPALFVGGALDAS 292 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W A AI+ +P +H++ GHWIQQE P E N LL D+L ++ Sbjct 293 TTWMADAIDAYPTTLPALSASHLLDGCGHWIQQERPNEVNSLLTDWLAAIQ 343 >gi|345003172|ref|YP_004806026.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] gi|344318798|gb|AEN13486.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] Length=328 Score = 270 bits (689), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 153/351 (44%), Positives = 196/351 (56%), Gaps = 34/351 (9%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR + R+H V GPLV+L+HGFPESWYSWR Q+PA+A AG+R VAID RG Sbjct 11 HRTVETPAGRLHLVEQG----TGPLVLLVHGFPESWYSWRRQLPAVAAAGHRAVAIDVRG 66 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSS+ AYR+ +LV D V V+ + G E A VVGHDWG+ +A + A LHP+ V Sbjct 67 YGRSSRPAATDAYRMLDLVEDNVAVVRALGEESAVVVGHDWGSNIAASSALLHPEVFRAV 126 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 +SVP+A PG P RP+D + GP + +Y YF EIE D+RG Sbjct 127 GLLSVPYAP------PGGP----RPTDVFDRIGGPEQEFYVSYFQEPGRAEAEIEPDVRG 176 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G +S + M A + P +A G RL+D F + Sbjct 177 WLAGFYAALSADTMPAQGE-------------------PDPHFVAHGGRLRDRFPA-DRA 216 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 PAW +EADLDFY EFER+G G L+ Y +D DW DLA +G P+ P+LFIGG D Sbjct 217 PAWLSEADLDFYAAEFERTGLTGALNRYRAMDRDWEDLAPHRGAPIKQPSLFIGGTLDAS 276 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W A A++ +P +H++ GHWIQQE P E NRLL D+L LR Sbjct 277 TTWMADALDAYPATLPALSASHLLEGCGHWIQQERPAEVNRLLTDWLATLR 327 >gi|297154269|gb|ADI03981.1| epoxide hydrolase [Streptomyces bingchenggensis BCW-1] Length=324 Score = 269 bits (687), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 153/352 (44%), Positives = 195/352 (56%), Gaps = 37/352 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR++ RIH V GPLV+L+HGFPESWYSWRHQ+P LA AGYR VAID R Sbjct 7 THRLVPTPAGRIHLVEQG----TGPLVLLVHGFPESWYSWRHQLPVLAAAGYRAVAIDVR 62 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSSK AYR+ +L+ D V+D+ G + A +VGHDWG+P+A A + PD Sbjct 63 GYGRSSKPESMAAYRMLDLIEDNAAVVDALGEQTAVIVGHDWGSPIAANSALVRPDV--- 119 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 F G++ +P +P G RPS+ + G + Y YF EIE D+R Sbjct 120 -------FRAVGLLSVPYTPRGGPRPSEIFARMGGDDEL-YVSYFQAPGRAEAEIEPDVR 171 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPE- 242 GWL GL +S + M A P ++ G ++D F PE Sbjct 172 GWLAGLYAALSADTMPAPGS-------------------PDPHFISPGGTMRDRF--PEG 210 Query 243 TMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYD 302 +PAW +E DLD Y EFER+GF GPL+ Y N+D DW DLAD G PLT P+LF+GG D Sbjct 211 RLPAWLSEHDLDSYAAEFERTGFTGPLNRYRNMDRDWEDLADFDGAPLTQPSLFLGGALD 270 Query 303 VGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W A AI+ +P R H++ GHWIQQE EE N+ L D+LG L Sbjct 271 ASTTWLADAIKAYPTTLPGLRSCHILDGCGHWIQQERHEEVNQHLTDWLGSL 322 >gi|329937243|ref|ZP_08286842.1| epoxide hydrolase [Streptomyces griseoaurantiacus M045] gi|329303524|gb|EGG47410.1| epoxide hydrolase [Streptomyces griseoaurantiacus M045] Length=329 Score = 269 bits (687), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 155/351 (45%), Positives = 201/351 (58%), Gaps = 35/351 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 VHR++ R H V +GPLV+L+HGFPESWYSWRHQ+PALA AG+R VA+D R Sbjct 11 VHRLVPSPAGRTHLVEQG----EGPLVLLVHGFPESWYSWRHQLPALAAAGHRAVAMDVR 66 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ +AYR+ ELV D V V+++ G A VVGHDWG+ +A T A L P+ Sbjct 67 GYGRSSRPEAMEAYRMVELVEDCVAVVEALGERTAVVVGHDWGSNIAATCALLRPEVFRA 126 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+A PG P RP++ + G +Y YF EIE D+R Sbjct 127 VAMLSVPYAP------PGGP----RPTEVFARIGGEDE-FYVSYFQQPGRAEAEIEPDVR 175 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G+ +S + M AA + DP V R G R++D F + Sbjct 176 GWLAGVYAALSADTMPAAG-----------APDPHFVSR--------GGRMRDRFPA-DR 215 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P+W TE +LD Y GEFER+G G L+ Y N+D DW DL G +T P+LF GG D Sbjct 216 LPSWLTEEELDVYAGEFERTGLTGALNRYRNMDRDWADLTAHHGAAITQPSLFAGGAQDA 275 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W ++AIE +P G+H++ GHWIQQE PEE NRLL D+L GL Sbjct 276 STRWMSEAIEAFPHTLPGLVGSHLLEGCGHWIQQERPEEINRLLTDWLAGL 326 >gi|312197969|ref|YP_004018030.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c] gi|311229305|gb|ADP82160.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c] Length=325 Score = 267 bits (683), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 154/355 (44%), Positives = 203/355 (58%), Gaps = 37/355 (10%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 H++++ RGTRIH V + GPLV+ +HGFPESWYSWRHQ+PA+A AG+R VAID RG Sbjct 3 HQVVDARGTRIHCVEEG----SGPLVLFVHGFPESWYSWRHQLPAVAEAGFRAVAIDVRG 58 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAE--QAFVVGHDWGAPVAWTFAWLHPDRCA 122 YGRSS +AY + + V D +GV++ A +VGHDWGAP+A A L PD Sbjct 59 YGRSSAPLEVEAYGMLQHVNDNLGVVEGLAGRGSPAVIVGHDWGAPIAAHSALLRPDIFT 118 Query 123 GVVGISVPFAGRGVIGLPGSPFGERRPSDYHLE---LAGPGRVWYQDYFAVQDGIITEIE 179 V +SVP+ SP G RRP++ E LAGP +Y +YF EIE Sbjct 119 AVALLSVPY----------SPPGGRRPTEAFAEMGRLAGPDHEFYINYFQEPGRAEREIE 168 Query 180 EDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFV 239 D+R WLLG Y S +T AG +A G L+D+F Sbjct 169 LDVRSWLLG-GYVASSADGFTSTPDGHTAG-----------------TVAPGGMLRDSFP 210 Query 240 YPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGG 299 P +P W TE DL FY EFER+GF G L+ Y N+D DW DL +G P+ P+LFI G Sbjct 211 VPHRLPDWLTEDDLAFYVEEFERTGFRGALNRYRNVDRDWRDLQPWRGAPIRVPSLFIAG 270 Query 300 QYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 + D +WG++AI R + +P RG+H++ GHW+QQE +E NRLL+D+L L Sbjct 271 EKDAPALWGSRAIARFPDTLPGLRGSHILPGCGHWLQQERADEVNRLLVDWLTTL 325 >gi|326781325|ref|ZP_08240590.1| Soluble epoxide hydrolase [Streptomyces cf. griseus XylebKG-1] gi|326661658|gb|EGE46504.1| Soluble epoxide hydrolase [Streptomyces griseus XylebKG-1] Length=348 Score = 266 bits (681), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 156/352 (45%), Positives = 191/352 (55%), Gaps = 35/352 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HRIL+ G RIH V GPLV+L+HGFPESWYSWRHQ+PALA AG+R VAID R Sbjct 26 THRILDVPGGRIHCVEQG----TGPLVLLIHGFPESWYSWRHQLPALAAAGHRAVAIDVR 81 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS AYR+ V D V+ + G E A VVGHDWG+P+A A L PD Sbjct 82 GYGRSSAPAAADAYRMLAHVADNTAVVHALGEETATVVGHDWGSPIAANSALLRPDVFTA 141 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+ +P G RP+D + G +Y YF EIE D+R Sbjct 142 VALLSVPY----------TPRGGPRPTDGFAGIGG-EEEFYVSYFQSPGRAEAEIEPDVR 190 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +SG+ T A+ D GP + GAR+ D F Sbjct 191 GWLTGFYTALSGD-----TPASED--------------HPGPFFVPPGARMADRFPG-GP 230 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P W E DLD Y EFER+G G L+ Y N+D DW DLA G P+T P++FIGG D Sbjct 231 LPGWLDERDLDVYAEEFERTGLAGALNRYRNVDRDWEDLAAWDGVPVTQPSIFIGGALDA 290 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W + AI +P H++ GHWIQQE P+E NRLL D+L GLR Sbjct 291 STTWMSDAIAAYPRTLPGLSAAHVLEGCGHWIQQERPDEVNRLLTDWLHGLR 342 >gi|182440651|ref|YP_001828370.1| putative epoxide hydrolase [Streptomyces griseus subsp. griseus NBRC 13350] gi|178469167|dbj|BAG23687.1| putative epoxide hydrolase [Streptomyces griseus subsp. griseus NBRC 13350] Length=348 Score = 266 bits (680), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 154/352 (44%), Positives = 188/352 (54%), Gaps = 35/352 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HRIL+ G RIH V GPLV+L+HGFPESWYSWRHQ+PALA AG+R VAID R Sbjct 26 THRILDVPGGRIHCVEQG----TGPLVLLVHGFPESWYSWRHQLPALAAAGHRAVAIDVR 81 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS AYR+ V D V+ + G E A VVGHDWG+P+A A L PD Sbjct 82 GYGRSSAPAAADAYRMLAHVADNTAVVHALGEETATVVGHDWGSPIAANSALLRPDVFTA 141 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+ +P G RP+D + G +Y YF EIE D+R Sbjct 142 VALLSVPY----------TPRGGPRPTDGFAGIGG-EEEFYVSYFQTPGRAEAEIEPDVR 190 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +SG+ P GP + GAR+ D F Sbjct 191 GWLTGFYTALSGDA-------------------PASEDHPGPFFVPPGARMADRFPG-GP 230 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P W E DLD Y EFER+G G L+ Y N+D DW DLA G P+T P++FIGG D Sbjct 231 LPGWLDERDLDVYAEEFERTGLAGALNRYRNVDRDWEDLAAWDGVPVTQPSIFIGGALDA 290 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W + AI +P H++ GHWIQQE P+E NRLL D+L GLR Sbjct 291 STTWMSDAIAAYPRTLPGLSAAHVLEGCGHWIQQERPDEVNRLLTDWLHGLR 342 >gi|291452892|ref|ZP_06592282.1| epoxide hydrolase [Streptomyces albus J1074] gi|291355841|gb|EFE82743.1| epoxide hydrolase [Streptomyces albus J1074] Length=332 Score = 263 bits (673), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 151/351 (44%), Positives = 190/351 (55%), Gaps = 36/351 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 VHR + R H V GPLV+L+HGFPESWYSWRHQ+PALA AGYR VAID R Sbjct 16 VHRTVATPAGRTHLVEQG----TGPLVLLVHGFPESWYSWRHQLPALAAAGYRAVAIDVR 71 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ AYR+ ELV D V V+ + G +A VVGHDWG+ +A A PD Sbjct 72 GYGRSSRPADPAAYRMTELVADCVAVVHALGEGEAVVVGHDWGSRIAADAALTRPDVFRA 131 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+ P G RPS+ + G +Y YF EIE D+R Sbjct 132 VALLSVPY----------EPHGGPRPSEMFARMGGDDE-FYVSYFQQPGRAEAEIEPDVR 180 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G+ +S + M ++ DP + R G + +P+ Sbjct 181 GWLSGVYAALSADTMPGP-----------DAPDPHFISRGGTMRQR----------FPDA 219 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 PAW TEADLDFY GEFER+G G L+ Y N+D DW DLA+ G P+ P+LF+GG D Sbjct 220 RPAWLTEADLDFYAGEFERTGVTGALNRYRNMDRDWEDLAEYDGAPIVQPSLFLGGALDA 279 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W + AI +P +H++ D GHW+QQE P E N LL FL GL Sbjct 280 STTWLSDAIAAYPRTLPGLVASHLLDDSGHWLQQERPAEVNHLLTAFLAGL 330 >gi|254381781|ref|ZP_04997145.1| epoxide hydrolase [Streptomyces sp. Mg1] gi|194340690|gb|EDX21656.1| epoxide hydrolase [Streptomyces sp. Mg1] Length=326 Score = 256 bits (654), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 155/354 (44%), Positives = 193/354 (55%), Gaps = 35/354 (9%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 ++ HR++ G RIH V GPLV+L+HGFPESWYSWRHQ+PALA AGYR AI Sbjct 6 MNVTHRMVPSPGGRIHVVEQG----AGPLVLLVHGFPESWYSWRHQLPALASAGYRAAAI 61 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 D RGYGRSSK +AYR+ ELV D V+++ G A VVGHDWG+ +A A L PD Sbjct 62 DVRGYGRSSKPGDLEAYRMLELVEDNAAVVEALGERSAVVVGHDWGSVIAANSALLRPDV 121 Query 121 CAGVVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 V +SVP+A P G RPS+ + G G +Y YF EIE Sbjct 122 FRAVGMLSVPYA----------PRGGPRPSEVFARMGG-GEEFYVAYFQEPGRAEAEIEP 170 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 D+RGWL G+ SG D + DP V R+G RL+D F Sbjct 171 DVRGWLAGIYAAFSG-----------DTTAGPGAPDPHFVSRSG--------RLRDRFPA 211 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 +P W +E +LDFY GEFER+G G L Y N+D DW DLA G P+T P+LF+GG Sbjct 212 GR-LPGWLSEDELDFYAGEFERTGMTGALHRYRNMDRDWEDLAGFDGAPITQPSLFVGGA 270 Query 301 YDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 D T W A AI+ +P + ++ GHWIQQE P E NRLL +L L Sbjct 271 LDASTTWMADAIKAYPATLPGLVTSEVLDGCGHWIQQERPAEINRLLTGWLAAL 324 >gi|344997863|ref|YP_004800717.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] gi|344313489|gb|AEN08177.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] Length=335 Score = 255 bits (652), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 147/348 (43%), Positives = 193/348 (56%), Gaps = 35/348 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 VHR+++ G RIH + GPLV+L+HGFPE+ YSWRHQ+PALA AG+R VA+D R Sbjct 18 VHRLVDVPGGRIHLLEQG----TGPLVLLIHGFPETSYSWRHQLPALAEAGFRAVAVDVR 73 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS R AYR+ LV D V V+ + G E A VVGHDWG+P+A A L PD Sbjct 74 GYGRSSAPRAVDAYRMTALVADNVAVVHALGEETATVVGHDWGSPIAANSALLRPDLFTA 133 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 +SVP+ SP+ RP++ + G G +Y YF EIE D+R Sbjct 134 AAFLSVPY----------SPWNPVRPTEAFARIGG-GEEFYISYFQEPGRAEAEIEPDVR 182 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL GL ++S ++M P D + P + GA+++D F Sbjct 183 GWLAGLYASLSA-----------------DTMPPPD--QGSPYFVPPGAQMRDRFT-DGP 222 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P+W TE DLD Y+ EFER+G G L+ Y N+D DW DLA G L+ P+LF+GG D Sbjct 223 LPSWLTEEDLDVYSAEFERTGLTGGLNRYRNVDRDWEDLAAWDGAVLSQPSLFLGGSLDS 282 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFL 351 T W A AI + +P +H+I GHWIQQE E N LL +L Sbjct 283 STTWMADAIAAYPDTLPGLVSSHLIEGCGHWIQQERASEVNTLLTRWL 330 >gi|295835404|ref|ZP_06822337.1| epoxide hydrolase [Streptomyces sp. SPB74] gi|295825478|gb|EDY43444.2| epoxide hydrolase [Streptomyces sp. SPB74] Length=323 Score = 255 bits (651), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 141/347 (41%), Positives = 195/347 (57%), Gaps = 38/347 (10%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR+ + G R+HAV +GPLV+LLHGFPESWY+WRHQ+PALA AGYR VA+D RG Sbjct 10 HRLFDLPGGRVHAVEQG----EGPLVLLLHGFPESWYAWRHQLPALAAAGYRAVAVDARG 65 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSS+ +AYR L G++V ++ + G E+A + GHDWGA +A L P+ V Sbjct 66 YGRSSRPEGSEAYRALALTGELVALVRALGEERAVLAGHDWGATLAGQAGLLRPEVFRAV 125 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 ++G+P +P G RPS+ + G + F + G E+E D+RG Sbjct 126 A----------LLGVPYTPPGGPRPSEVFASMGGEEEFYVP--FLQRPGAEAEMERDVRG 173 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G T+SG + GP + G +++ FV + Sbjct 174 WLAGFYATLSGRS---------------------GSVPPGPFFVPRGHAMRERFVT-GPL 211 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 P+W E LDFY EFER+GFGG L+ Y +D DW DLA +G+PL P+LF+ G+ D Sbjct 212 PSWLGEDVLDFYAAEFERTGFGGALARYRVMDRDWEDLAAWEGEPLRQPSLFLAGREDAS 271 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFL 351 W + A++ +P RGTH++ D GHW+QQE PEE N LLL++L Sbjct 272 LAWLSDAVDAFPHTLPGLRGTHLLDDCGHWVQQERPEEVNTLLLEWL 318 >gi|119477846|ref|ZP_01617969.1| putative epoxide hydrolase [marine gamma proteobacterium HTCC2143] gi|119449007|gb|EAW30248.1| putative epoxide hydrolase [marine gamma proteobacterium HTCC2143] Length=320 Score = 254 bits (648), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 153/357 (43%), Positives = 200/357 (57%), Gaps = 40/357 (11%) Query 1 VSQVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAI 60 V HR ++ RIH +GP V+++HGFPESWYSWR Q+P LA GY VA+ Sbjct 2 VEITHRTVSSNNIRIHLAEAG----EGPTVLMIHGFPESWYSWREQLPVLAEQGYHAVAM 57 Query 61 DQRGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDR 120 D RGYGRSSK + + YR+ V DVVGV+D+ + +VGHDWGAP+AW A L PD Sbjct 58 DVRGYGRSSKPQNVEDYRMMLKVADVVGVVDAIDNGKVTIVGHDWGAPIAWNSALLRPDL 117 Query 121 CAGVVGISVPF-AGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIE 179 +GV G+SVP+ AG GV+ RP++ +AG +Y ++F EIE Sbjct 118 FSGVAGLSVPYSAGGGVV----------RPTELFAMMAGDDD-FYINHFQEVGKAEREIE 166 Query 180 EDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAE-GARLKDAF 238 D+R W+LG + G DVI + M G L + F Sbjct 167 ADVRQWILGFYWGAGG-----------------------DVIDGPNISMVRRGGTLSEKF 203 Query 239 VYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIG 298 VYP+ MP W T+ DLD YT EFE SGF GPLS Y N+D DW D + G+P+ P+LFIG Sbjct 204 VYPDVMPDWMTDKDLDVYTREFEYSGFFGPLSRYRNVDRDWEDFSAFAGQPIAIPSLFIG 263 Query 299 GQYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 G+ D TIWGA AI ++ +P + ++ GHWIQQE E TN LLL+FL L+ Sbjct 264 GEKDGPTIWGASAIANYNQTLPKLFKSEILPGAGHWIQQERAERTNELLLEFLNSLK 320 >gi|29828647|ref|NP_823281.1| epoxide hydrolase [Streptomyces avermitilis MA-4680] gi|29605751|dbj|BAC69816.1| putative epoxide hydrolase [Streptomyces avermitilis MA-4680] Length=328 Score = 254 bits (648), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 150/351 (43%), Positives = 195/351 (56%), Gaps = 35/351 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR+++ RIH V GPLV+L+HGFPESWYSWRHQ+PALA AGYR VA+D R Sbjct 11 THRLVSSPAGRIHLVEQG----TGPLVLLVHGFPESWYSWRHQLPALAAAGYRAVAVDVR 66 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ AYR+ +LV D V V+ + G A +VGHDWG+ +A T A + PD Sbjct 67 GYGRSSRPNAVHAYRMLDLVEDNVAVVHALGERTAVIVGHDWGSNIAATSALVRPDV--- 123 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 F G++ +P +P G RPS+ + G +Y YF EIE D+R Sbjct 124 -------FRAVGLLSVPYTPRGGPRPSEIFAGMGG-DEEFYVSYFQEPGRAEAEIEPDVR 175 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +S + M A ++ DP V R G L++ F Sbjct 176 GWLAGFYAALSADTMPAP-----------DAPDPHFVRR--------GGTLRERFPAGR- 215 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +PAW +EADLD Y GEFER+G G L+ Y +D DW DLA G P+ P+LFIGG D Sbjct 216 LPAWLSEADLDVYAGEFERTGLSGALNRYRAMDRDWEDLAPFDGAPVRQPSLFIGGGLDA 275 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W A AIE +P +H++ GHW+QQE P++TNRLL D+L L Sbjct 276 STQWLADAIEAYPVTLPGLVSSHILDGCGHWLQQERPQDTNRLLTDWLASL 326 >gi|297199344|ref|ZP_06916741.1| epoxide hydrolase [Streptomyces sviceus ATCC 29083] gi|297147376|gb|EDY59358.2| epoxide hydrolase [Streptomyces sviceus ATCC 29083] Length=343 Score = 253 bits (645), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 149/351 (43%), Positives = 189/351 (54%), Gaps = 29/351 (8%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR++ RIH V GPLV+LLHGFPESWYSWRHQ+P LA AGYR VA+D R Sbjct 18 THRLVPGPAGRIHLVEQG----TGPLVLLLHGFPESWYSWRHQLPVLAAAGYRAVAVDVR 73 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ AYR+ ELV D V+++ G A VVGHDWGA +A A L P+ Sbjct 74 GYGRSSRPEAVAAYRMTELVEDNAAVVEALGERSAVVVGHDWGATIAAHSALLKPEVFHA 133 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SVP+ +P G RPS+ + G +Y YF EIE D+R Sbjct 134 VALLSVPY----------TPPGGPRPSEVFAGIGGE-EEFYVSYFQEPGRAEREIEPDVR 182 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +S + M +T A D P +A G +L+D F Sbjct 183 GWLAGFYAALSADTMPTSTADAHHMPAD-------------PHFVAPGGQLRDRFPAGR- 228 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +PAW TE DLD Y GEFER+G G L+ Y +D DW DLA G P+ P+LF+GG D Sbjct 229 LPAWLTEDDLDVYAGEFERTGLTGALNRYRAMDQDWKDLAAYAGAPIRRPSLFLGGALDA 288 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W + AI+ +P H++ GHWIQQE PEE R L ++LG + Sbjct 289 STTWLSDAIDAFPTTLPGLHAAHLLDGCGHWIQQERPEEVGRHLTEWLGSV 339 >gi|302523212|ref|ZP_07275554.1| epoxide hydrolase [Streptomyces sp. SPB78] gi|302432107|gb|EFL03923.1| epoxide hydrolase [Streptomyces sp. SPB78] Length=338 Score = 251 bits (642), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 138/350 (40%), Positives = 200/350 (58%), Gaps = 37/350 (10%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR+L G R+H V +GPLV+LLHGFPESW++WRHQ+P LA AGYR VA+D RG Sbjct 24 HRLLALPGGRVHVVEQG----EGPLVLLLHGFPESWHAWRHQLPVLAAAGYRAVAVDARG 79 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSS+ +AYR LVG++V ++ + G E+A + GHDWGA +A L P+ Sbjct 80 YGRSSRPGDTEAYRAVALVGELVALVRALGEERAVLAGHDWGATLAGQAGLLRPEV---- 135 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 F+ ++G+P +P G RPS+ + G +Y + E+E+D+RG Sbjct 136 ------FSAIALLGVPYTPPGGPRPSEVFAAMGGE-EEFYVPFLQRPGVAEAEMEQDVRG 188 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G T+SG V+ GP + G +++ FV + Sbjct 189 WLAGFYTTLSGRS---------------------GVVPPGPFFVPRGHAMRERFV-DGPL 226 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 P+W +E +LD + GEFER+GFGG L+ Y +D DW DLA +G+PL P+LF+ G+ D Sbjct 227 PSWLSEEELDVHAGEFERTGFGGALARYRVMDRDWEDLAAWEGEPLRQPSLFLAGREDAS 286 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 W ++A++ +P RGTH++ D GHW+QQE P+E LL+++L GL Sbjct 287 LAWLSEAVDAFPRTLPGLRGTHLLDDCGHWVQQERPDEVGALLVEWLAGL 336 >gi|337762851|emb|CCB71559.1| putative epoxide hydrolase [Streptomyces cattleya NRRL 8057] Length=327 Score = 248 bits (634), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 150/351 (43%), Positives = 188/351 (54%), Gaps = 35/351 (9%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 VHR++ RIH V +GPLV+L+HGFPESWYSWRHQ+P LA AGYR VA+D R Sbjct 10 VHRLVPSPAGRIHLVEQG----RGPLVLLVHGFPESWYSWRHQLPVLAAAGYRAVAVDVR 65 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYGRSS+ AYR+ ELV D V V+ + G E A +VGHDWG+ +A T A + P+ Sbjct 66 GYGRSSRPEGADAYRLLELVEDNVAVVRALGEESAVIVGHDWGSTIAATSALVRPEVFRA 125 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V +SV +A P G RPS+ GP +Y YF EIE D+R Sbjct 126 VGLLSVAYA----------PPGGPRPSEVFAGTPGP-EEFYVSYFQQPGRAEAEIEPDVR 174 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +S + M A D D P +A G L++ F Sbjct 175 GWLAGFYAALSADTMPGA--------------DAPD-----PHFVAPGGTLRERFPS-GR 214 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 P W EA+LD Y EFER+G G L Y +D DW DLA G P+T P+LF+GG D Sbjct 215 RPGWLGEAELDVYAAEFERTGLTGALGRYRAMDRDWADLAPYNGAPVTCPSLFVGGALDA 274 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W A AI +P G+H++ GHWIQQE PE NRLL ++L L Sbjct 275 STTWLADAIAAYPTTLPALHGSHLLDGCGHWIQQERPETVNRLLTEWLAAL 325 >gi|333022985|ref|ZP_08451049.1| putative epoxide hydrolase [Streptomyces sp. Tu6071] gi|332742837|gb|EGJ73278.1| putative epoxide hydrolase [Streptomyces sp. Tu6071] Length=324 Score = 246 bits (627), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 136/350 (39%), Positives = 198/350 (57%), Gaps = 37/350 (10%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR+L G R+H V +GPLV+LLHGFPES ++WRHQ+P LA AGYR VA++ RG Sbjct 10 HRLLALPGGRVHVVEQG----EGPLVLLLHGFPESLHAWRHQLPVLAAAGYRAVAVEARG 65 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSS+ +AYR LVG++V ++ + G E+A + GHDWGA +A L P+ Sbjct 66 YGRSSRPGDTEAYRAVALVGELVSLVRALGEERAVLAGHDWGATLAGQAGLLRPEM---- 121 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 F+ ++G+P +P G RPS+ + G +Y + E+E+D+RG Sbjct 122 ------FSAIALLGVPYTPPGGPRPSEVFAAMGGE-EEFYVPFLQRPGVAEAEMEQDVRG 174 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G T+SG V+ GP + G +++ FV + Sbjct 175 WLAGFYTTLSGRS---------------------GVVPPGPFFVPRGHAMRERFV-DGPL 212 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 P+W +E +LD Y EFER+GFGG L+ Y +D DW DLA +G+PL P+LF+ G+ D Sbjct 213 PSWLSEEELDVYAAEFERTGFGGALARYRVMDRDWEDLAAWEGEPLRQPSLFLAGREDAS 272 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 W ++A++ +P RGTH++ D GHW+QQE P+E LL+++L GL Sbjct 273 LAWLSEAVDAFPRTLPGLRGTHLLDDCGHWVQQERPDEVGALLVEWLAGL 322 >gi|318061383|ref|ZP_07980104.1| epoxide hydrolase [Streptomyces sp. SA3_actG] gi|318079564|ref|ZP_07986896.1| epoxide hydrolase [Streptomyces sp. SA3_actF] Length=305 Score = 244 bits (623), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 132/329 (41%), Positives = 191/329 (59%), Gaps = 33/329 (10%) Query 26 QGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGD 85 +GPLV+LLHGFPESW++WRHQ+P LA AGYR VA+D RGYGRSS+ +AYR LVG+ Sbjct 8 EGPLVLLLHGFPESWHAWRHQLPVLAAAGYRAVAVDARGYGRSSRPGAPEAYRAVALVGE 67 Query 86 VVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFG 145 +V ++ + G E+A + GHDWGA +A L P+ F+ ++G+P +P G Sbjct 68 LVALVRALGEERAVLAGHDWGATLAGQAGLLRPEV----------FSAIALLGVPYTPPG 117 Query 146 ERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAA 205 RPS+ + G +Y + E+E+D+RGWL G T+SG Sbjct 118 GPRPSEVFAAMGGE-EEFYVPFLQRPGVAEAEMEQDVRGWLAGFYTTLSGRS-------- 168 Query 206 VDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGF 265 V+ GP + G +++ FV +P+W +E +LD Y GEFER+GF Sbjct 169 -------------GVVPPGPFFVPRGHAMRERFV-DGPLPSWLSEEELDVYAGEFERTGF 214 Query 266 GGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYRGT 325 GG L+ Y +D DW DLA +G+PL P+LF+ G+ D W ++A++ +P RGT Sbjct 215 GGALARYRVMDRDWEDLAAWEGEPLRQPSLFLAGREDASLAWLSEAVDAFPRTLPGLRGT 274 Query 326 HMIADVGHWIQQEAPEETNRLLLDFLGGL 354 H++ D GHW+QQE P+E LL+++L GL Sbjct 275 HLLDDCGHWVQQERPDEVGALLVEWLAGL 303 >gi|320008071|gb|ADW02921.1| alpha/beta hydrolase fold protein [Streptomyces flavogriseus ATCC 33331] Length=328 Score = 243 bits (619), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 151/351 (44%), Positives = 193/351 (55%), Gaps = 34/351 (9%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR + RIH V GPLV+L+HGFPESWYSWR Q+PALA AGYR AID RG Sbjct 11 HRTVEAPAGRIHLVEQG----TGPLVLLVHGFPESWYSWRRQLPALAAAGYRAAAIDVRG 66 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRSS+ AYR+ +LV D + V+ + G E A V+GHDWG+ +A A LHP V Sbjct 67 YGRSSRPAATDAYRMLDLVEDNLAVVRALGEESAVVIGHDWGSNIAAASALLHPAVFRAV 126 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 +SVP+A PG P RP+D + G + +Y YF EIE D+RG Sbjct 127 GLLSVPYAP------PGGP----RPTDVFSRIGGAEQEFYVSYFQEPGRAEAEIEPDVRG 176 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 WL G +S + M A DP P +A G RL+D F E + Sbjct 177 WLAGFYAALSADTMPA-------------EGDP------DPHFVAHGGRLRDRFPAGE-L 216 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 PAW +E +LD Y EFER+G G L+ Y N+D DW DLA +G P+ P+LF+GG D Sbjct 217 PAWLSEDELDVYAAEFERTGLTGALNRYRNMDRDWEDLAPHRGAPIEQPSLFVGGTLDAS 276 Query 305 TIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 T W A A++ +P +H+ GHWIQQE P+E NRLL D+L L+ Sbjct 277 TTWMADAVDAHPRTLPGLSASHLPEGCGHWIQQERPDEVNRLLTDWLRTLQ 327 >gi|29830353|ref|NP_824987.1| epoxide hydrolase [Streptomyces avermitilis MA-4680] gi|29607464|dbj|BAC71522.1| putative epoxide hydrolase [Streptomyces avermitilis MA-4680] Length=333 Score = 234 bits (596), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 152/355 (43%), Positives = 190/355 (54%), Gaps = 42/355 (11%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR+++ G R+H +GPLVVLLHGFPES YSWRHQ LA AG+RVVA DQRG Sbjct 12 HRMIDVNGIRLHIAEQG----EGPLVVLLHGFPESSYSWRHQFGPLAAAGFRVVAPDQRG 67 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRS + AY I LVGDV+G++ + G E A+VVGHDWGAPVAW A L PD GV Sbjct 68 YGRSDRPESVDAYTILHLVGDVIGLIHALGEETAYVVGHDWGAPVAWHTALLRPDVVRGV 127 Query 125 VGISVPFAGRGVIGLPGSPF-GERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 G+SVP PF GER P D E+ +Y +YFA E D R Sbjct 128 AGLSVP-----------PPFRGERPPLDAMDEMF--DGQFYWNYFAQPGVADAEFGRDAR 174 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 G L Y+ SG+ A AG + + +A G D PE Sbjct 175 GSLRKFLYSASGD--------APGAGSGRQPL------------VAPGRGFLDGMPDPEV 214 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P W TEADLD + EF GF G L++Y N+D +W A QG ++PPAL++ G D Sbjct 215 LPGWITEADLDVFAEEFA-PGFTGALNWYRNLDRNWELTAAWQGAVVSPPALYMYGDRDA 273 Query 304 GTIW--GAQAIERAHEVMPNYRGTHMI-ADVGHWIQQEAPEETNRLLLDFLGGLR 355 + A+ IE+ +MPN R ++ GHW QQE P E N L+DFL GLR Sbjct 274 VPAFPGTAELIEKLPALMPNLRREPLVLPGCGHWTQQERPNEVNAALVDFLTGLR 328 >gi|284045280|ref|YP_003395620.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] gi|283949501|gb|ADB52245.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] Length=330 Score = 231 bits (590), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 142/351 (41%), Positives = 184/351 (53%), Gaps = 36/351 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR+++ G RIH V GPLV+LLHGFPESW +WR Q+PALA AGYR VA+D R Sbjct 13 THRLVDVPGGRIHLVEQG----TGPLVLLLHGFPESWRAWRRQLPALAAAGYRAVALDLR 68 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYG SS+ R+ V D V V+ + G E A VVGHD GA +A A L PD Sbjct 69 GYGGSSQPAAVADCRMLAHVADDVAVVRALGEETAIVVGHDVGASIAANSALLRPDV--- 125 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 F G++G+P +P G RP+D ++ G + +Y +F EIE D+R Sbjct 126 -------FTAVGLLGVPYTPRGGPRPTDAFAQIGGDEQ-FYVSWFQEPGVAEAEIERDVR 177 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 GWL G +S + M AA A + G ++D F Sbjct 178 GWLAGFYAALSADTMGAAGGAYA--------------------FVPPGRAMRDRFPA-GA 216 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +PAW + +LD EFE +GF G L+ Y N D DW DLA G P+ P+LFIGG D Sbjct 217 LPAWLSPDELDGSAQEFEETGFAGALARYRNFDRDWEDLAAWDGAPIRQPSLFIGGALDP 276 Query 304 GTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T W A AI +P +H++ GHW+QQE P+E NRLLLD+LG L Sbjct 277 STTWMADAIAAFPATLPGLVSSHLLDGCGHWLQQERPDEVNRLLLDWLGSL 327 >gi|326386649|ref|ZP_08208271.1| epoxide hydrolase [Novosphingobium nitrogenifigens DSM 19370] gi|326208964|gb|EGD59759.1| epoxide hydrolase [Novosphingobium nitrogenifigens DSM 19370] Length=326 Score = 223 bits (567), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 140/333 (43%), Positives = 180/333 (55%), Gaps = 37/333 (11%) Query 26 QGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGD 85 +GPLVV++HGFPESWYSWRHQI +A AGY+V AID RGYG S K + AY ++ +VGD Sbjct 26 EGPLVVMVHGFPESWYSWRHQIGPVAAAGYKVAAIDVRGYGGSDKPQDIAAYAMEAIVGD 85 Query 86 VVGVLDSYGAEQ-AFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPF 144 VVG+ + A +VGHDWGAP+ W A+ PD V G+SVPF G+P PF Sbjct 86 VVGLKQVLQPDAPAILVGHDWGAPIVWNSAFTRPDLFRAVAGLSVPF-----TGVPQRPF 140 Query 145 GERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKA 204 + + G +YQ+YF E+E D+R L + SG Sbjct 141 TQV----FRELFTAKGLFFYQEYFQEPGRAEAELEADVRRSLRLFLTSASG--------- 187 Query 205 AVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSG 264 DA + P D + L D+ PE +P W +EADLDFYT EF SG Sbjct 188 --DAPASAWAPKPAD------------SNLLDSLPEPERLPDWLSEADLDFYTAEFTASG 233 Query 265 FGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYD-VGTIWG--AQAIERAHEVMPN 321 F GPL+ Y N + D+ L+ G+ L PAL+IGG D T++G A + P+ Sbjct 234 FRGPLNRYRNHEADYAWLSQFAGRTLDQPALYIGGTRDPASTLFGQVADPVAMMRRFAPH 293 Query 322 YRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 G HM+ GHW QQE PEE NRLLLD+L GL Sbjct 294 VVG-HMLEGCGHWTQQERPEEVNRLLLDWLAGL 325 >gi|302552187|ref|ZP_07304529.1| epoxide hydrolase [Streptomyces viridochromogenes DSM 40736] gi|302469805|gb|EFL32898.1| epoxide hydrolase [Streptomyces viridochromogenes DSM 40736] Length=322 Score = 223 bits (567), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 152/355 (43%), Positives = 190/355 (54%), Gaps = 39/355 (10%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR+++ G R+H +GPLVVLLHGFPESW+SWRHQ LA AG+RVVA DQR Sbjct 3 THRMIDVNGIRLHIAEQG----EGPLVVLLHGFPESWHSWRHQFGPLAEAGFRVVAPDQR 58 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYG S AY I LVGDVVG++ + G E+AFVVGHDWGAPVAW A L PD G Sbjct 59 GYGGSDHPEDVSAYSILHLVGDVVGLIHALGEERAFVVGHDWGAPVAWHTALLRPDVVRG 118 Query 124 VVGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 V G+SVP RG G P P E G GR +Y +YF E D R Sbjct 119 VAGLSVPPPFRG-----GQP-----PLATMRERFG-GR-FYWNYFEQPGVAEAEFSADTR 166 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 L L Y+ SG+ A AG +++ +D + G L A PE Sbjct 167 ATLRKLLYSASGD--------APGAGRPEQAL--VDDLERGWLADAPD---------PEV 207 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P W TE DLD T + + GF G L++Y N+D +W A QG ++PPAL++ G D+ Sbjct 208 LPEWLTEEDLDTLTESYAQ-GFTGALNWYRNLDRNWELTAPWQGAVVSPPALYVYGDRDL 266 Query 304 GTIW--GAQAIERAHEVMPNYRGTHMI-ADVGHWIQQEAPEETNRLLLDFLGGLR 355 + + IE E+MPN R ++ GHW QQE P E N LLDFL LR Sbjct 267 VPAFPGTPELIEELPELMPNLRRKPLVLPGCGHWTQQERPTEVNEALLDFLTELR 321 >gi|108762454|ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622] gi|108466334|gb|ABF91519.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622] Length=318 Score = 219 bits (557), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 132/355 (38%), Positives = 176/355 (50%), Gaps = 47/355 (13%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR + G +H GPLV+LLHG+PESWYSWRHQ+PALA AGY VA D R Sbjct 5 THRTVKTNGINLHLAEAG----SGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDVR 60 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GYG+S K +AY +K+LVGD VG+LD+ G A V+GHDWG+ +AW A LHPDR Sbjct 61 GYGQSDKPEAIEAYSMKQLVGDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFRA 120 Query 124 VVGISVPFAGRGVI---GLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGII-TEIE 179 VVG+SVP GR + L FGE+ W+ + + G+ E E Sbjct 121 VVGMSVPHLGRAPMPPMQLFQRMFGEK---------------WFYILYFQEPGVAEAEFE 165 Query 180 EDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFV 239 D+ + + G DV L +G Sbjct 166 ADVPRTVRAILTGTPG----------------------FDVTNPAVLAKKKGEGFLARLD 203 Query 240 YPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGG 299 PET+P W TEAD+ ++ E SGF G L+ Y N+D DWH+L + ++ PAL+I G Sbjct 204 VPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRNMDRDWHELPELATAVISQPALYIVG 263 Query 300 QYDVGTIWGAQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 + D + ++ ++PN H+I GHW+QQE E N LL FL L Sbjct 264 EKD--PVRAFSPVDPMKALVPNLADIHVIPGAGHWVQQEHAAEVNAALLAFLKKL 316 >gi|294632870|ref|ZP_06711429.1| epoxide hydrolase [Streptomyces sp. e14] gi|292830651|gb|EFF89001.1| epoxide hydrolase [Streptomyces sp. e14] Length=320 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 144/350 (42%), Positives = 180/350 (52%), Gaps = 42/350 (12%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR++N G R+H + +GPLVVLLHGFPESW SWRHQ LA AGYRVVA DQRG Sbjct 4 HRMVNVNGVRLHIAEEG----EGPLVVLLHGFPESWRSWRHQFGPLAEAGYRVVAPDQRG 59 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YGRS +AY I LVGDVVG++ G E+A+VVGHDWGAPVAW A L PD GV Sbjct 60 YGRSDHPAEVEAYTILHLVGDVVGLIRELGEEKAYVVGHDWGAPVAWHTALLRPDLVLGV 119 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 G+SVP PF RP ++ A GR +Y +YF E D R Sbjct 120 AGLSVP-----------PPFRGSRPPLAAMDKAFGGR-FYWNYFDRPGVADAEFARDTRT 167 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 L Y SG+ + PL E L A PET+ Sbjct 168 GLRKFVYAASGDAPGPVKQ---------------------PLVDPERGWLA-AMPDPETL 205 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVG 304 P WFTE+DLD T F GF G L++Y N+D +W A G +T PAL++ G+ D+ Sbjct 206 PEWFTESDLDALTESFA-GGFTGALNWYRNLDRNWELTAPWAGAVVTSPALYVYGERDLV 264 Query 305 TIW--GAQAIERAHEVMPNYRGTHM-IADVGHWIQQEAPEETNRLLLDFL 351 + + I++ ++MP R + + GHW QQE P E LLDF Sbjct 265 PAFPGTPELIKKLPDLMPGLRRPPLELPGCGHWTQQERPAEVTEALLDFF 314 >gi|297200409|ref|ZP_06917806.1| epoxide hydrolase [Streptomyces sviceus ATCC 29083] gi|197709529|gb|EDY53563.1| epoxide hydrolase [Streptomyces sviceus ATCC 29083] Length=322 Score = 218 bits (554), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 147/355 (42%), Positives = 184/355 (52%), Gaps = 41/355 (11%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR+++ G R+H + +GPLVVLLHGFPESW+SWRHQ LA AG+RVVA DQRG Sbjct 4 HRMVDVNGIRLHIAEEG----EGPLVVLLHGFPESWHSWRHQFGPLAAAGFRVVAPDQRG 59 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YG S AY I LVGDVVG++ + G E+AFVVGHDWGAPVAW A L PD GV Sbjct 60 YGASDHPEDVSAYSILHLVGDVVGLVHALGEERAFVVGHDWGAPVAWHTALLRPDVVRGV 119 Query 125 VGISVPFAGRGVIGLPGSPF-GERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLR 183 G+SVP PF GER P E G W +YF + E D R Sbjct 120 AGLSVP-----------PPFRGERPPLQTMQERFGGHFYW--NYFNLPGAADAEFGADPR 166 Query 184 GWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPET 243 L ++ + G E D+ R M E PE Sbjct 167 SAL---------RRLLVGASGDGEGGGRYEQALVTDLERGWLADMPE----------PEV 207 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 +P W TE DLD T + + GF G L++Y N+D +W A G +TPPAL++ G D+ Sbjct 208 LPGWLTEQDLDELTESYAK-GFTGALNWYRNLDRNWELTAPWHGARVTPPALYMYGDRDL 266 Query 304 GTIW--GAQAIERAHEVMPNY-RGTHMIADVGHWIQQEAPEETNRLLLDFLGGLR 355 + + IER E+MPN R ++ GHW QQE P+E N L+DFL GLR Sbjct 267 VPAFPGTPELIERLPELMPNLVRDPVLLPGCGHWTQQERPDEVNAALVDFLTGLR 321 >gi|27376225|ref|NP_767754.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110] gi|27349365|dbj|BAC46379.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110] Length=330 Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 126/331 (39%), Positives = 173/331 (53%), Gaps = 27/331 (8%) Query 26 QGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKELVGD 85 +GP+V+L HGFPE WYSWRHQ+ ALA AGY VA D RGYG+S + Y I +VGD Sbjct 23 KGPMVLLCHGFPEGWYSWRHQLEALAAAGYHAVAPDMRGYGKSDRPEAIDQYTILHMVGD 82 Query 86 VVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFAGRGVIGLPGSPFG 145 +VGVLD++ + A +VGHDWGA +AW A L PDR +SVP+ P Sbjct 83 LVGVLDAFEVKDAVIVGHDWGATIAWHTARLRPDRFRAAAILSVPY----------RPRS 132 Query 146 ERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWLLGLTYTVSGEGMMAATKAA 205 E RP+ + A +YQ YF E E D R L + Y SGEG A +A Sbjct 133 EARPTSVMPQTADAQ--FYQLYFQEPGVAEAEFERDPRATLGAMLYGGSGEGAAAIRASA 190 Query 206 VDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGF 265 AG + G + +G K +P+W + DLD+Y+ EF RSGF Sbjct 191 ERAG---------RTVGVGMVSRKDGMLPKVQV----PLPSWLSATDLDYYSAEFARSGF 237 Query 266 GGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIW--GAQAIERAHEVMPNYR 323 GPL++Y NID +W + +G + P+LFI G +D+ + A+ + + +P R Sbjct 238 RGPLNYYRNIDRNWELMGAFEGVKVVVPSLFIAGDHDMVIAFPGAAEHLANMKQFVPQLR 297 Query 324 GTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 ++ GHW QQE P E N +++FL L Sbjct 298 EIKILPGCGHWTQQERPTEVNAAIVEFLRSL 328 >gi|197104586|ref|YP_002129963.1| epoxide hydrolase [Phenylobacterium zucineum HLK1] gi|196478006|gb|ACG77534.1| epoxide hydrolase [Phenylobacterium zucineum HLK1] Length=321 Score = 215 bits (547), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 133/353 (38%), Positives = 180/353 (51%), Gaps = 40/353 (11%) Query 6 RILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGY 65 R+++ RI A +GPLVVL+HGFPESW+SWRHQI +A AG+ AID RGY Sbjct 5 RMVDAGEVRIRAALKG----EGPLVVLVHGFPESWFSWRHQIDPIADAGFTACAIDVRGY 60 Query 66 GRSSKYRVQKAYRIKELVGDVVGVLDSYG-AEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 G S K +AY ++ L DV GV+ + A ++GHDWGAP+ W A P+ V Sbjct 61 GGSDKPHPVEAYAMERLTADVAGVVRALQPGAPAILIGHDWGAPIVWNTALARPESVRAV 120 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 G+SVP+ +G+P PF E + GR +YQ +F + E E D+RG Sbjct 121 GGLSVPY-----LGIPSRPFTEV----FDALFTQKGRFFYQAWFQKEGPPEAEAEADVRG 171 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETM 244 +L Y +SG+ A GA L + + P+ Sbjct 172 FLRKFYYAISGDAPPGAWPQK-----------------------PAGATLLEGLIDPDPF 208 Query 245 PAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYD-V 303 PAW TE +LD+Y EF SGF GP++ Y N + D+ L QG+ + PALFIGG D Sbjct 209 PAWLTENELDYYEAEFRESGFRGPINRYRNHERDFAWLQGFQGRTIEQPALFIGGTKDPA 268 Query 304 GTIWG--AQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 T +G + I +PN HM+ GHW QQE PEE RL+L++L GL Sbjct 269 STAFGGLSDPIAAMRPHVPNLVSAHMLEGCGHWTQQERPEEVTRLILEWLKGL 321 >gi|150018674|ref|YP_001310928.1| alpha/beta hydrolase fold protein [Clostridium beijerinckii NCIMB 8052] gi|149905139|gb|ABR35972.1| alpha/beta hydrolase fold [Clostridium beijerinckii NCIMB 8052] Length=325 Score = 214 bits (546), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 132/353 (38%), Positives = 180/353 (51%), Gaps = 36/353 (10%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HRI+ G ++H +GPLV+LLHGFPE WYSWR+QIP LA AGY VV D RG Sbjct 6 HRIVETNGIKMHIAEQG----KGPLVLLLHGFPEIWYSWRNQIPVLAEAGYHVVVPDLRG 61 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YG + K Y + LVGD+VG+LD+ E A +VG+DWGA +AW A L PD+ GV Sbjct 62 YGDTEKPENIDQYTLLHLVGDIVGLLDALNEETAVIVGNDWGATIAWNAALLRPDKFKGV 121 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 + ++VP + I P + F + ++Y YF E E+D R Sbjct 122 IALTVPMMPQPPIS-PTTVFPQNNE-----------ELFYTLYFQTPGVAEKEFEKDARF 169 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGAR-LKDAFVYPET 243 + L Y+ SG+ A + D P M + L A P+ Sbjct 170 AVHNLLYSASGD---AGPRKGNDG-------------TPNPFSMVSREKGLLSALPMPK- 212 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYDV 303 M +W E DL+ YT F ++GF G L++Y N+D + L+ G +T PALF+ G DV Sbjct 213 MTSWLKEKDLEVYTEAFYKTGFSGGLNYYRNLDRNRELLSCFNGLKVTIPALFMVGTRDV 272 Query 304 G-TIWGA-QAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 G +I G Q I ++PN R T + D GHW QQE PEE + ++ FL L Sbjct 273 GLSIPGMDQIISEMKSIVPNIRQTIFLEDCGHWAQQEKPEEVSTAIISFLKSL 325 >gi|269125887|ref|YP_003299257.1| alpha/beta hydrolase fold protein [Thermomonospora curvata DSM 43183] gi|268310845|gb|ACY97219.1| alpha/beta hydrolase fold protein [Thermomonospora curvata DSM 43183] Length=317 Score = 214 bits (546), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 139/357 (39%), Positives = 180/357 (51%), Gaps = 50/357 (14%) Query 4 VHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQR 63 HR + G +H VA++ GPLVVLLHGFPE WYSWRHQ+ ALA AG+ VA DQR Sbjct 5 THRTIEVNGLNMH-VAEA---GSGPLVVLLHGFPECWYSWRHQLTALAEAGFHAVAPDQR 60 Query 64 GYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAG 123 GY R+ + Y I LVGDVV ++ + G E+A VVGHDWGAPVAW A PD G Sbjct 61 GYARTGGPQRVAEYSILHLVGDVVALIAALGEERAVVVGHDWGAPVAWHTAQFRPDLVRG 120 Query 124 VVGISV---PFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEE 180 VVG+SV P R + + FGE G V +Q+ + ++ + Sbjct 121 VVGLSVHPRPRTSRPPVAVMREQFGE-----------GFYMVAFQEPKRPEAAFERDVAD 169 Query 181 DLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVY 240 R L Y +SG D M P+ + EG D Sbjct 170 TFRRTL----YALSG---------------DAPGMLPV---------VPEGGSFLDVCPA 201 Query 241 PETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQ 300 PE +P W TE D+ Y EF SGF GPL++Y N+D +W A P+TPPAL+I G+ Sbjct 202 PERLPGWLTEDDIAVYAAEFAASGFTGPLNWYRNLDRNWELTAAWHRAPITPPALYIAGE 261 Query 301 YDVGTIWG---AQAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 D+ + G + + R E +P+ R ++ GHW QQE P E N LL FL GL Sbjct 262 RDM-VLAGPGVKERLSRLREFVPDLRDIVLLPGCGHWTQQERPREVNEALLAFLRGL 317 >gi|345010956|ref|YP_004813310.1| alpha/beta hydrolase fold containing protein [Streptomyces violaceusniger Tu 4113] gi|344037305|gb|AEM83030.1| alpha/beta hydrolase fold containing protein [Streptomyces violaceusniger Tu 4113] Length=319 Score = 213 bits (541), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 143/348 (42%), Positives = 183/348 (53%), Gaps = 42/348 (12%) Query 7 ILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYG 66 +++ G R+H + +GPLVVLLHGFPESW+SW HQ L AG+RVVA DQRGYG Sbjct 1 MVDTNGIRLHIAEEG----EGPLVVLLHGFPESWHSWHHQFGPLVEAGFRVVAPDQRGYG 56 Query 67 RSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVG 126 RS AY I LVGDVVG++ + G ++A+VVGHDWGAPVAW A L PD GV G Sbjct 57 RSDHPDDVDAYSILHLVGDVVGLIRALGEDKAYVVGHDWGAPVAWNTALLRPDMVLGVAG 116 Query 127 ISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRGWL 186 +SVP PF +P +E GR +Y +YF E+ D R L Sbjct 117 LSVP-----------PPFRGAQPPLAAMEKRFGGR-FYWNYFNRPGVADAELARDTRTAL 164 Query 187 LGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGARLKDAFVYPETMPA 246 + Y++SG+ A D G PL E L P+ +P Sbjct 165 RKIFYSISGD--------APDTGEQ-------------PLVAPEQGWLA-TMTDPDVLPE 202 Query 247 WFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYD-VGT 305 WFTE DLD T F + GF G L++Y N+D +W A +TPPAL+I G D V Sbjct 203 WFTEEDLDALTESFSK-GFTGALNWYRNLDRNWELTAPWHDAVVTPPALYIYGDRDPVPA 261 Query 306 IWGA-QAIERAHEVMPNYRGTHM-IADVGHWIQQEAPEETNRLLLDFL 351 GA + I R ++MPN R + +A GHW QQE P E N L++FL Sbjct 262 FPGAPELIARLPDLMPNLRRAPLELAGCGHWTQQERPAEVNAALIEFL 309 >gi|320108864|ref|YP_004184454.1| alpha/beta hydrolase fold protein [Terriglobus saanensis SP1PR4] gi|319927385|gb|ADV84460.1| alpha/beta hydrolase fold protein [Terriglobus saanensis SP1PR4] Length=319 Score = 212 bits (540), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 135/353 (39%), Positives = 180/353 (51%), Gaps = 42/353 (11%) Query 5 HRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRG 64 HR L+ G RIH +GPLV+L HGFPE WYSWRHQ+ ALA AG+ VA D RG Sbjct 6 HRTLDSNGIRIHIAEQG----KGPLVLLCHGFPEGWYSWRHQLKALAEAGFHAVAPDMRG 61 Query 65 YGRSSKYRVQKAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV 124 YG + + ++Y + LVGD+VG+LD+ G +QA +VGHDWGAPVAW A + PD V Sbjct 62 YGETDRPEAVESYTLLHLVGDMVGLLDALGEKQAVIVGHDWGAPVAWNAAIMRPDLFRAV 121 Query 125 VGISVPFAGRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDLRG 184 G+SVP R + RP+ + +WY YF +E+E D+R Sbjct 122 AGLSVPLLPRPSV----------RPTSLMARM--DEFIWYILYFQSLGIAESELERDVRA 169 Query 185 WLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGAR-LKDAFVYPET 243 + YT+ G G G D P D I M + R L P Sbjct 170 SI----YTIFGSGF----------GED----QPSDRI-----GMVDSTRGLLHGMSKPMN 206 Query 244 MPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDLADQQGKPLTPPALFIGGQYD- 302 +P+W +E DLD +T +F +GF G L++Y NID +W LA +T P+L+I G D Sbjct 207 LPSWLSEQDLDHFTKQFTNTGFTGALNWYRNIDRNWELLAPFANANITVPSLYIYGDRDV 266 Query 303 VGTIWGA-QAIERAHEVMPNYRGTHMIADVGHWIQQEAPEETNRLLLDFLGGL 354 VG G + I + RG + D GHW QQE P E + L++FL L Sbjct 267 VGRFPGMDKTIAGLSNRALDLRGKLCLKDCGHWTQQEQPAEVSTALINFLKDL 319 Lambda K H 0.321 0.141 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 666948571488 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40