BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1940
Length=353
Score E
Sequences producing significant alignments: (Bits) Value
gi|15841411|ref|NP_336448.1| 3,4-dihydroxy-2-butanone-4-phosphat... 701 0.0
gi|253799013|ref|YP_003032014.1| riboflavin biosynthesis protein... 699 0.0
gi|340626950|ref|YP_004745402.1| putative riboflavin biosynthesi... 699 0.0
gi|289750523|ref|ZP_06509901.1| riboflavin biosynthesis protein ... 694 0.0
gi|183982872|ref|YP_001851163.1| riboflavin biosynthesis protein... 498 7e-139
gi|118618304|ref|YP_906636.1| riboflavin biosynthesis protein Ri... 495 4e-138
gi|289570026|ref|ZP_06450253.1| riboflavin biosynthesis protein ... 468 9e-130
gi|120404954|ref|YP_954783.1| 3,4-dihydroxy-2-butanone 4-phospha... 429 3e-118
gi|289762094|ref|ZP_06521472.1| riboflavin biosynthesis protein ... 310 2e-82
gi|324999978|ref|ZP_08121090.1| 3,4-dihydroxy-2-butanone-4-phosp... 297 2e-78
gi|111026875|ref|YP_708853.1| 3,4-dihydroxy-2-butanone-4-phospha... 287 2e-75
gi|312139595|ref|YP_004006931.1| 3,4-dihydroxy-2-butanone 4-phos... 265 1e-68
gi|325676730|ref|ZP_08156404.1| 3,4-dihydroxy-2-butanone 4-phosp... 264 1e-68
gi|111024120|ref|YP_707092.1| bifunctional 3,4-dihydroxy-2-butan... 264 2e-68
gi|226366360|ref|YP_002784143.1| bifunctional 3,4-dihydroxy-2-bu... 264 2e-68
gi|317508956|ref|ZP_07966589.1| 3,4-dihydroxy-2-butanone 4-phosp... 263 3e-68
gi|262202282|ref|YP_003273490.1| GTP cyclohydrolase II [Gordonia... 263 3e-68
gi|134098693|ref|YP_001104354.1| bifunctional 3,4-dihydroxy-2-bu... 263 3e-68
gi|291003620|ref|ZP_06561593.1| bifunctional 3,4-dihydroxy-2-but... 263 4e-68
gi|226306509|ref|YP_002766469.1| riboflavin biosynthesis bifunct... 262 5e-68
gi|343924573|ref|ZP_08764121.1| riboflavin biosynthesis protein ... 261 1e-67
gi|257055603|ref|YP_003133435.1| bifunctional 3,4-dihydroxy-2-bu... 260 2e-67
gi|15608553|ref|NP_215931.1| bifunctional 3,4-dihydroxy-2-butano... 260 3e-67
gi|308231835|ref|ZP_07413935.2| riboflavin biosynthesis protein ... 259 3e-67
gi|333919549|ref|YP_004493130.1| GTP cyclohydrolase-2 [Amycolici... 258 8e-67
gi|289447011|ref|ZP_06436755.1| riboflavin biosynthesis protein ... 258 8e-67
gi|68536085|ref|YP_250790.1| bifunctional 3,4-dihydroxy-2-butano... 258 1e-66
gi|302525889|ref|ZP_07278231.1| 3,4-dihydroxy-2-butanone 4-phosp... 258 1e-66
gi|330466991|ref|YP_004404734.1| bifunctional 3,4-dihydroxy-2-bu... 257 2e-66
gi|340626429|ref|YP_004744881.1| putative riboflavin biosynthesi... 257 3e-66
gi|169629880|ref|YP_001703529.1| bifunctional 3,4-dihydroxy-2-bu... 257 3e-66
gi|289442860|ref|ZP_06432604.1| riboflavin biosynthesis protein ... 256 3e-66
gi|41407238|ref|NP_960074.1| bifunctional 3,4-dihydroxy-2-butano... 256 4e-66
gi|118464982|ref|YP_882547.1| bifunctional 3,4-dihydroxy-2-butan... 256 5e-66
gi|254775811|ref|ZP_05217327.1| bifunctional 3,4-dihydroxy-2-but... 256 5e-66
gi|118617424|ref|YP_905756.1| bifunctional 3,4-dihydroxy-2-butan... 254 1e-65
gi|296395031|ref|YP_003659915.1| GTP cyclohydrolase II [Segnilip... 254 2e-65
gi|312195563|ref|YP_004015624.1| 3,4-dihydroxy-2-butanone 4-phos... 254 2e-65
gi|260578780|ref|ZP_05846687.1| 3,4-dihydroxy-2-butanone 4-phosp... 254 2e-65
gi|342858708|ref|ZP_08715363.1| bifunctional 3,4-dihydroxy-2-but... 253 2e-65
gi|254822409|ref|ZP_05227410.1| bifunctional 3,4-dihydroxy-2-but... 253 3e-65
gi|15827210|ref|NP_301473.1| bifunctional 3,4-dihydroxy-2-butano... 253 3e-65
gi|319948955|ref|ZP_08023060.1| bifunctional 3,4-dihydroxy-2-but... 253 4e-65
gi|183982235|ref|YP_001850526.1| riboflavin biosynthesis protein... 253 4e-65
gi|240172788|ref|ZP_04751447.1| bifunctional 3,4-dihydroxy-2-but... 253 5e-65
gi|256379225|ref|YP_003102885.1| 3,4-dihydroxy-2-butanone 4-phos... 252 5e-65
gi|296170720|ref|ZP_06852294.1| 3,4-dihydroxy-2-butanone 4-phosp... 252 6e-65
gi|118470936|ref|YP_887388.1| bifunctional 3,4-dihydroxy-2-butan... 251 9e-65
gi|108799357|ref|YP_639554.1| bifunctional 3,4-dihydroxy-2-butan... 251 9e-65
gi|54025570|ref|YP_119812.1| bifunctional 3,4-dihydroxy-2-butano... 251 1e-64
>gi|15841411|ref|NP_336448.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase
II [Mycobacterium tuberculosis CDC1551]
gi|31793132|ref|NP_855625.1| riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II)
[Mycobacterium bovis AF2122/97]
gi|57116930|ref|YP_177851.1| riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II)
[Mycobacterium tuberculosis H37Rv]
70 more sequence titles
Length=353
Score = 701 bits (1810), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 353/353 (100%), Positives = 353/353 (100%), Gaps = 0/353 (0%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL
Sbjct 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH
Sbjct 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE
Sbjct 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG
Sbjct 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
Query 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF
Sbjct 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
Query 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
>gi|253799013|ref|YP_003032014.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
KZN 1435]
gi|313658827|ref|ZP_07815707.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
KZN V2475]
gi|253320516|gb|ACT25119.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
KZN 1435]
Length=353
Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 352/353 (99%), Positives = 352/353 (99%), Gaps = 0/353 (0%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL
Sbjct 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH
Sbjct 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE
Sbjct 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWA ASRVIGFRDVYDLGEHLAVIVGAVG
Sbjct 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWASASRVIGFRDVYDLGEHLAVIVGAVG 240
Query 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF
Sbjct 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
Query 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
>gi|340626950|ref|YP_004745402.1| putative riboflavin biosynthesis protein ribA1 [Mycobacterium
canettii CIPT 140010059]
gi|340005140|emb|CCC44289.1| putative riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase
II) [Mycobacterium canettii CIPT 140010059]
Length=353
Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 352/353 (99%), Positives = 352/353 (99%), Gaps = 0/353 (0%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL
Sbjct 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH
Sbjct 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE
Sbjct 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
HGLAMVSIGELVAYRRRIEPQVVRFTAATL TWAGASRVIGFRDVYDLGEHLAVIVGAVG
Sbjct 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLSTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
Query 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF
Sbjct 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
Query 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
>gi|289750523|ref|ZP_06509901.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
T92]
gi|289691110|gb|EFD58539.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
T92]
Length=353
Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 350/353 (99%), Positives = 351/353 (99%), Gaps = 0/353 (0%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
M+TTD VRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL
Sbjct 1 METTDGAVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH
Sbjct 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE
Sbjct 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG
Sbjct 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVG 240
Query 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF
Sbjct 241 AGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLF 300
Query 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 301 ARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
>gi|183982872|ref|YP_001851163.1| riboflavin biosynthesis protein RibA1 [Mycobacterium marinum
M]
gi|54289555|gb|AAV32088.1| putative cyclohydrolase [Mycobacterium marinum]
gi|183176198|gb|ACC41308.1| riboflavin biosynthesis protein RibA1 [Mycobacterium marinum
M]
Length=365
Score = 498 bits (1282), Expect = 7e-139, Method: Compositional matrix adjust.
Identities = 267/357 (75%), Positives = 290/357 (82%), Gaps = 6/357 (1%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
MKTTDVRVRRAITA+A G VV+T D GYLVFAA+AAT LVAF VRHT+GY+RVAL
Sbjct 1 MKTTDVRVRRAITAIAAGRPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAEC RL+LPPMC + TH VSVDVR TGTGISA DRA TIAALASA S AADF RPGH
Sbjct 61 PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIAALASAGSQAADFLRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
V P+ A+ GVL + PAEAAVDLARLA RPAAALCEIVS NP MAH AE VEFAVE
Sbjct 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDV---YDLGEHLAVIVG 237
HGLA+VSI EL+AYR+R EPQV+R T TLPTWAG SRVIGFRD+ GEHLAVI+G
Sbjct 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
Query 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297
A +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
Query 298 GLFARGDAA-TDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
GLFA + D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMFGAIREA AAAG
Sbjct 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMFGAIREAG--AAAG 355
>gi|118618304|ref|YP_906636.1| riboflavin biosynthesis protein RibA1 [Mycobacterium ulcerans
Agy99]
gi|118570414|gb|ABL05165.1| riboflavin biosynthesis protein RibA1 [Mycobacterium ulcerans
Agy99]
Length=365
Score = 495 bits (1275), Expect = 4e-138, Method: Compositional matrix adjust.
Identities = 265/357 (75%), Positives = 290/357 (82%), Gaps = 6/357 (1%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60
MKTTDVRVRRAITA+A G VV+T D GYLVFAA+AAT LVAF VRHT+GY+RVAL
Sbjct 1 MKTTDVRVRRAITAIAAGRPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
Query 61 PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120
PGAEC RL+LPPMC + TH VSVDVR TGTGISA DRA TIAALASA S AADF RPGH
Sbjct 61 PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIAALASAGSQAADFLRPGH 120
Query 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180
V P+ A+ GVL + PAEAAVDLARLA RPAAALCEIVS NP MAH AE VEFAVE
Sbjct 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
Query 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDV---YDLGEHLAVIVG 237
HGLA+VSI EL+AYR+R EPQV+R T TLPTWAG SRVIGFRD+ GEHLAV++G
Sbjct 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVVIG 240
Query 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297
A +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYL+PPGP +AC
Sbjct 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLQPPGPPRAC 300
Query 298 GLFARGDAA-TDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
GLFA + D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMFGAIREA AAAG
Sbjct 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMFGAIREAG--AAAG 355
>gi|289570026|ref|ZP_06450253.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
T17]
gi|289543780|gb|EFD47428.1| riboflavin biosynthesis protein ribA1 [Mycobacterium tuberculosis
T17]
Length=273
Score = 468 bits (1203), Expect = 9e-130, Method: Compositional matrix adjust.
Identities = 247/272 (91%), Positives = 248/272 (92%), Gaps = 10/272 (3%)
Query 87 RGTGTGISAS-----DRAWTIAALASATSVAADFQRPGHVVPVQAQADGVLGRRGPAEAA 141
RGTGTGIS + R W L S R HVVPVQAQADGVLGRRGPAEAA
Sbjct 7 RGTGTGISRAIAPGPSRHW----LRPPPSPPISNVR-AHVVPVQAQADGVLGRRGPAEAA 61
Query 142 VDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVEHGLAMVSIGELVAYRRRIEPQ 201
VDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVEHGLAMVSIGELVAYRRRIEPQ
Sbjct 62 VDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVEHGLAMVSIGELVAYRRRIEPQ 121
Query 202 VVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDVFGS 261
VVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDVFGS
Sbjct 122 VVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDVFGS 181
Query 262 TACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWILRDL 321
TACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWILRDL
Sbjct 182 TACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWILRDL 241
Query 322 GVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
GVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 242 GVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 273
>gi|120404954|ref|YP_954783.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
vanbaalenii PYR-1]
gi|119957772|gb|ABM14777.1| GTP cyclohydrolase II [Mycobacterium vanbaalenii PYR-1]
Length=359
Score = 429 bits (1103), Expect = 3e-118, Method: Compositional matrix adjust.
Identities = 231/360 (65%), Positives = 272/360 (76%), Gaps = 11/360 (3%)
Query 1 MKTTDVRVRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRV 58
M+TTD+RVRRAI A+A G VV+T D G GYLVFAA AATP ++AF VRHTSG +RV
Sbjct 1 MRTTDLRVRRAIRAVAEGRPVVVTADTEREGAGYLVFAADAATPNILAFTVRHTSGLVRV 60
Query 59 ALPGAECERLHLPPMC--DRDTTHC----VSVDVRGTGTGISASDRAWTIAALASATSVA 112
ALP +EC RL LPPMC D D +H V+VD G GTGISA+DRA TIAALAS +
Sbjct 61 ALPLSECARLDLPPMCSADPDGSHAAAQRVAVDAGGNGTGISATDRARTIAALASEHAQP 120
Query 113 ADFQRPGHVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHA 172
DF+RPGHV+PVQA ADGVLG G EAAVDLARL+ RR AA LCEIVS ++P +A
Sbjct 121 GDFRRPGHVIPVQANADGVLGSPGAVEAAVDLARLSGRRQAAGLCEIVSRNHPATIACGT 180
Query 173 ESVEFAVEHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHL 232
E VEFA+EHGLA VSIGELVAYRRR E QVVR LPT G RVIGFRDV+ EHL
Sbjct 181 EPVEFALEHGLATVSIGELVAYRRRTERQVVRLAETVLPTGCGTHRVIGFRDVHGGAEHL 240
Query 233 AVIVGAVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPG 292
+++G+VG+G PVPLHVH+ECLTGDVFGST C CG EL+ A+A MSAQG GV++YLRPPG
Sbjct 241 VLVIGSVGSGEPVPLHVHVECLTGDVFGSTVCHCGAELDSAVATMSAQGGGVIVYLRPPG 300
Query 293 PAQACGLFARGD--AATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLA 350
+ACGL R D + D++ +TV WILRDLGVY++RL+DD PG+GLVMFGA+R+ T A
Sbjct 301 SLRACGL-PRPDHSPSPDLLSDTVAWILRDLGVYSLRLADDAPGYGLVMFGALRQNRTAA 359
>gi|289762094|ref|ZP_06521472.1| riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II)
[Mycobacterium tuberculosis GM 1503]
gi|289709600|gb|EFD73616.1| riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II)
[Mycobacterium tuberculosis GM 1503]
Length=326
Score = 310 bits (795), Expect = 2e-82, Method: Compositional matrix adjust.
Identities = 153/155 (99%), Positives = 154/155 (99%), Gaps = 0/155 (0%)
Query 199 EPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDV 258
P+VVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDV
Sbjct 172 SPRVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAVGAGVPVPLHVHIECLTGDV 231
Query 259 FGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWIL 318
FGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWIL
Sbjct 232 FGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGLFARGDAATDVMPETVTWIL 291
Query 319 RDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 353
RDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
Sbjct 292 RDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG 326
>gi|324999978|ref|ZP_08121090.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase
II [Pseudonocardia sp. P1]
Length=368
Score = 297 bits (760), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 177/347 (52%), Positives = 225/347 (65%), Gaps = 8/347 (2%)
Query 7 RVRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAE 64
RV RA+ +A G V++T D + +G L+FAA+AAT + +AF VR+TSG++ VALP +
Sbjct 15 RVTRAVQEIAAGRPVIVTDDADREDEGDLIFAAEAATAQTLAFTVRYTSGFVCVALPEDD 74
Query 65 CERLHLPPMCDRD-----TTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPG 119
C+RL L PM R+ T + V+VD+ GTGISAS RA TIAALAS + A+DF RPG
Sbjct 75 CDRLDLSPMHGRNGDRYQTAYQVTVDLAANGTGISASARARTIAALASERARASDFVRPG 134
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A++ GVL R G EAAVDLARLA RPA ALCEIVS ++P QMA E V FA
Sbjct 135 HVVPLRARSGGVLVRPGHTEAAVDLARLAGMRPAGALCEIVSEEHPGQMARGPELVRFAG 194
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+HGL +VSI EL+ +R+R EPQVVR A L T AG IG+R V+D GEHLA++ G V
Sbjct 195 QHGLVIVSISELMEHRKRTEPQVVRRADAALATDAGRLHAIGYRGVHDNGEHLALVAGDV 254
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGL 299
VP++VH+ECLTGDV G+ +C CG L A ++A G GV++Y+RPPG QACGL
Sbjct 255 AGARDVPVYVHVECLTGDVLGARSCGCGAHLERGRAMIAANG-GVLVYVRPPGGVQACGL 313
Query 300 FARGDAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREA 346
F + V P +L DLGV L D G REA
Sbjct 314 FDTEVGGSVVAPSVSRSVLADLGVVTAVLIDMSDSSGDRSVQVCREA 360
>gi|111026875|ref|YP_708853.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase
II [Rhodococcus jostii RHA1]
gi|110825414|gb|ABH00695.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP cyclohydrolase
II [Rhodococcus jostii RHA1]
Length=355
Score = 287 bits (735), Expect = 2e-75, Method: Compositional matrix adjust.
Identities = 178/332 (54%), Positives = 218/332 (66%), Gaps = 12/332 (3%)
Query 2 KTTDVRVRRAITAMAGGHAVVL--TGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVA 59
T + RVR A+TA+A G VV+ D G+G L+FAA AT LVAF VRHTSG++ VA
Sbjct 13 DTAEQRVRNALTAIAAGRPVVVIDAADREGEGDLIFAAALATTELVAFTVRHTSGFVCVA 72
Query 60 LPGAECERLHLPPMC----DR-DTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAAD 114
LPG EC+RL LP M DR DT + ++VD+RGTGTGISA+ RA TIAALAS S+A+D
Sbjct 73 LPGDECDRLGLPAMHHSNDDRFDTAYRITVDMRGTGTGISAASRAATIAALASPDSLASD 132
Query 115 FQRPGHVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAES 174
F RPGHVVP+ A+ GVL R G EAAVDL RLA A ALCEIVS D PV MA E
Sbjct 133 FVRPGHVVPLMARPGGVLDRPGLTEAAVDLTRLAGVPAAGALCEIVSQDRPVDMARGPEL 192
Query 175 VEFAVEHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAV 234
FA EH L ++SI +L+ YR+R EPQV R +LPT G R +G+ +D EH+A+
Sbjct 193 ERFAKEHDLVLLSIADLIHYRQRTEPQVRRGAVTSLPTDFGRFRAVGYVGAHDGAEHMAL 252
Query 235 IVGAVGAGV--PVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPG 292
+V G VP+HVH ECL+GDVF STAC C +EL A+ + A+G GVVLYLRPPG
Sbjct 253 VVDPTGGRQFEEVPVHVHTECLSGDVFRSTACGCRQELEKAMFQFCAEGCGVVLYLRPPG 312
Query 293 PAQACGLFA--RGDAA-TDVMPETVTWILRDL 321
+ACG+FA R + + M WIL DL
Sbjct 313 GPRACGIFATERNEGVNSSAMQAVADWILADL 344
>gi|312139595|ref|YP_004006931.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase
ii ribba [Rhodococcus equi 103S]
gi|311888934|emb|CBH48247.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II RibBA [Rhodococcus equi 103S]
Length=415
Score = 265 bits (676), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 163/366 (45%), Positives = 219/366 (60%), Gaps = 36/366 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G +C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGEDC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD R G GTGISASDRA T+ LA T+ A DF RPG
Sbjct 67 DRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPTTGANDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A+ RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAKVDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +L+A+RR+ E VVR A +PT G +G++ +YD EH+A++ G +
Sbjct 187 DHDLALISIADLIAWRRKHEKHVVRVAEARIPTRHGDFTAVGYKSIYDEVEHVALVRGDI 246
Query 240 --GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----G 292
G G V + VH ECLTGDVFGS C CG +L+ AL ++ +G GVVLY+R G
Sbjct 247 AEGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMIAQEGRGVVLYMRGHEGRGIG 306
Query 293 PAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP----- 333
+ DA +D + + IL DLG+ ++RL + P
Sbjct 307 LMHKLQAYQLQDAGSDTVDANLQLGLPADARDYGIGAQILVDLGIKSMRLLTNNPAKRVG 366
Query 334 --GFGL 337
G+GL
Sbjct 367 LDGYGL 372
>gi|325676730|ref|ZP_08156404.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Rhodococcus equi ATCC 33707]
gi|325552512|gb|EGD22200.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Rhodococcus equi ATCC 33707]
Length=420
Score = 264 bits (675), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 163/366 (45%), Positives = 219/366 (60%), Gaps = 36/366 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G +C
Sbjct 12 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGEDC 71
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD R G GTGISASDRA T+ LA T+ A DF RPG
Sbjct 72 DRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPTTGANDFTRPG 131
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A+ RPA +CEIVS + MA E FA
Sbjct 132 HVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAKVDELRVFAD 191
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +L+A+RR+ E VVR A +PT G +G++ +YD EH+A++ G +
Sbjct 192 DHDLALISIADLIAWRRKHEKHVVRVAEARIPTRHGDFTAVGYKSIYDEVEHVALVRGDI 251
Query 240 --GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----G 292
G G V + VH ECLTGDVFGS C CG +L+ AL ++ +G GVVLY+R G
Sbjct 252 AEGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMIAQEGRGVVLYMRGHEGRGIG 311
Query 293 PAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP----- 333
+ DA +D + + IL DLG+ ++RL + P
Sbjct 312 LMHKLQAYQLQDAGSDTVDANLQLGLPADARDYGIGAQILVDLGIKSMRLLTNNPAKRVG 371
Query 334 --GFGL 337
G+GL
Sbjct 372 LDGYGL 377
>gi|111024120|ref|YP_707092.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Rhodococcus jostii RHA1]
gi|123144023|sp|Q0S0K2.1|RIBBA_RHOSR RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|110823650|gb|ABG98934.1| GTP cyclohydrolase II [Rhodococcus jostii RHA1]
Length=417
Score = 264 bits (675), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 164/368 (45%), Positives = 220/368 (60%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA+C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGADC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD R G GTGISASDRA T+ LA +S A DF RPG
Sbjct 67 DRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A+ RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +L+A+RR+ E V R +A +PT G +G+R +YD EH+A++ G +
Sbjct 187 DHNLALISIADLIAWRRKHEKHVERVASARIPTRHGEFTAVGYRSIYDDVEHVALVRGDL 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGDVFGS C CG +L+ AL ++ +G GVVLY+R
Sbjct 247 PGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA +D + + IL DLG+ ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|226366360|ref|YP_002784143.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Rhodococcus opacus B4]
gi|226244850|dbj|BAH55198.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Rhodococcus opacus B4]
Length=417
Score = 264 bits (674), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 164/368 (45%), Positives = 220/368 (60%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA+C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGADC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD R G GTGISASDRA T+ LA +S A DF RPG
Sbjct 67 DRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A+ RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +L+A+RR+ E V R +A +PT G +G+R +YD EH+A++ G +
Sbjct 187 DHDLALISIADLIAWRRKHEKHVERVASARIPTRHGEFTAVGYRSIYDDVEHVALVRGDL 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGDVFGS C CG +L+ AL ++ +G GVVLY+R
Sbjct 247 PGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA +D + + IL DLG+ ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|317508956|ref|ZP_07966589.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Segniliparus rugosus
ATCC BAA-974]
gi|316252721|gb|EFV12158.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Segniliparus rugosus
ATCC BAA-974]
Length=414
Score = 263 bits (673), Expect = 3e-68, Method: Compositional matrix adjust.
Identities = 162/367 (45%), Positives = 211/367 (58%), Gaps = 36/367 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G A+V+ D + +G L FAA+ ATP LVAF +RHTSGYL V + +C
Sbjct 7 IERAIKDIAEGKAIVVVDDEDRENEGDLTFAAEKATPELVAFMIRHTSGYLCVPMEEEDC 66
Query 66 ERLHLPPMC-----DRDTTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R T + V+VD R G GTGISA DRA TI LA+A + A+D RPG
Sbjct 67 DRLDLPPMYAVNQDRRGTAYTVTVDAREGVGTGISARDRAHTIQLLANAETKASDLTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
H+VP++A+ GVL R G EAAVDLARLA RPA +CEIVS + MA E FA
Sbjct 127 HMVPLRAKPGGVLRRPGHTEAAVDLARLAGLRPAGVICEIVSTKDEEHMAKGDELRVFAE 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA +SI +L+ YRRR E V R A LPT G R IG+ Y+ EH+A++ G +
Sbjct 187 EHNLARISIADLIRYRRRYEKHVRREAEARLPTRHGVFRAIGYSCAYEDAEHMAMVFGDI 246
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGL 299
G V + VH ECLTGDVFGS C CG +L+ A+ ++ +G GVVLY+R + GL
Sbjct 247 SNGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEIVAEEGRGVVLYMRGH-EGRGIGL 305
Query 300 FAR------GDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP------ 333
A+ D D + + IL DLG+ ++RL + P
Sbjct 306 LAKLRAYELQDGGADTVDANLQLGLPADARDYGVGAQILCDLGIRSMRLLTNNPAKRVGL 365
Query 334 -GFGLVM 339
G+GL +
Sbjct 366 DGYGLTI 372
>gi|262202282|ref|YP_003273490.1| GTP cyclohydrolase II [Gordonia bronchialis DSM 43247]
gi|262085629|gb|ACY21597.1| GTP cyclohydrolase II [Gordonia bronchialis DSM 43247]
Length=442
Score = 263 bits (672), Expect = 3e-68, Method: Compositional matrix adjust.
Identities = 168/366 (46%), Positives = 215/366 (59%), Gaps = 36/366 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL L G C
Sbjct 25 IERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCAPLDGDTC 84
Query 66 ERLHLPPMCDRD-----TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM + T + V+VD R G GTGISASDRA T+ LA S AADF RPG
Sbjct 85 DRLGLPPMYSMNQDKHGTAYTVTVDAREGIGTGISASDRATTMRLLADPASSAADFTRPG 144
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA PA +CEIVS + MA E FA
Sbjct 145 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLTPAGVICEIVSQKDVGSMAQTDELRVFAD 204
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVG-- 237
EH LA++SI +L+A+RRR E VVR A +PT G R +G+ VYD EH+A+++G
Sbjct 205 EHELALISIADLIAWRRRHEKHVVRVADARIPTRHGDFRAVGYSSVYDEVEHVALVMGDI 264
Query 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----G 292
A G G V + VH ECLTGDVFGS C CG +L+ A+ ++A+G G+VLY+R G
Sbjct 265 AAGDGHDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEMVAAEGRGIVLYMRGHEGRGIG 324
Query 293 PAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP----- 333
+ DA +D + + IL DLGV ++RL + P
Sbjct 325 LLHKLQAYQLQDAGSDTVDANLQLGLPADSRDYGLGAQILVDLGVSSMRLLTNNPAKRVG 384
Query 334 --GFGL 337
G+GL
Sbjct 385 LDGYGL 390
>gi|134098693|ref|YP_001104354.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Saccharopolyspora erythraea NRRL
2338]
gi|133911316|emb|CAM01429.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Saccharopolyspora
erythraea NRRL 2338]
Length=437
Score = 263 bits (672), Expect = 3e-68, Method: Compositional matrix adjust.
Identities = 163/368 (45%), Positives = 212/368 (58%), Gaps = 34/368 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G V++ D + +G L+FAA+ ATP +VAF VR+TSGY+ VAL G +C
Sbjct 24 IERALADIAAGRPVIVVDDEDRENEGDLIFAAEMATPEMVAFMVRYTSGYICVALTGEDC 83
Query 66 ERLHLPPMC----DRD-TTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM DR T + V+VD G TGISASDRA T+ LA A S A D RPG
Sbjct 84 DRLDLPPMYHWNQDRKGTAYTVTVDAAEGVSTGISASDRAHTLKVLAHADSSADDLNRPG 143
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDL+RLA RPA ALCEIVS + MA E FA
Sbjct 144 HVVPLRARDGGVLRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELEVFAD 203
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+++I +L+AYRRR E QVVR A +PT G R +G+ D EHLA++ G +
Sbjct 204 EHDLALITIADLIAYRRRFEQQVVRVAEARIPTAHGTFRTVGYDSTLDGIEHLALVYGDI 263
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G + + VH ECLTGDV GS C CG +L A+ +++ G GVVLY+R G
Sbjct 264 GDGEDILVRVHSECLTGDVLGSLRCDCGPQLAAAMEKVAEAGRGVVLYMRGHEGRGIGLM 323
Query 295 QACGLFARGDAATDVMPETV--------------TWILRDLGVYAIRLSDDVP------- 333
+ D D + V IL DLG+ ++RL + P
Sbjct 324 HKLQAYQLQDDGADTVDANVALGMPVDGRDYGQGAQILCDLGIKSMRLLTNNPAKRVGLE 383
Query 334 GFGLVMFG 341
G+GL + G
Sbjct 384 GYGLRVVG 391
>gi|291003620|ref|ZP_06561593.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Saccharopolyspora erythraea NRRL
2338]
Length=438
Score = 263 bits (671), Expect = 4e-68, Method: Compositional matrix adjust.
Identities = 163/368 (45%), Positives = 212/368 (58%), Gaps = 34/368 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G V++ D + +G L+FAA+ ATP +VAF VR+TSGY+ VAL G +C
Sbjct 25 IERALADIAAGRPVIVVDDEDRENEGDLIFAAEMATPEMVAFMVRYTSGYICVALTGEDC 84
Query 66 ERLHLPPMC----DRD-TTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM DR T + V+VD G TGISASDRA T+ LA A S A D RPG
Sbjct 85 DRLDLPPMYHWNQDRKGTAYTVTVDAAEGVSTGISASDRAHTLKVLAHADSSADDLNRPG 144
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDL+RLA RPA ALCEIVS + MA E FA
Sbjct 145 HVVPLRARDGGVLRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELEVFAD 204
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+++I +L+AYRRR E QVVR A +PT G R +G+ D EHLA++ G +
Sbjct 205 EHDLALITIADLIAYRRRFEQQVVRVAEARIPTAHGTFRTVGYDSTLDGIEHLALVYGDI 264
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G + + VH ECLTGDV GS C CG +L A+ +++ G GVVLY+R G
Sbjct 265 GDGEDILVRVHSECLTGDVLGSLRCDCGPQLAAAMEKVAEAGRGVVLYMRGHEGRGIGLM 324
Query 295 QACGLFARGDAATDVMPETV--------------TWILRDLGVYAIRLSDDVP------- 333
+ D D + V IL DLG+ ++RL + P
Sbjct 325 HKLQAYQLQDDGADTVDANVALGMPVDGRDYGQGAQILCDLGIKSMRLLTNNPAKRVGLE 384
Query 334 GFGLVMFG 341
G+GL + G
Sbjct 385 GYGLRVVG 392
>gi|226306509|ref|YP_002766469.1| riboflavin biosynthesis bifunctional protein RibA [Rhodococcus
erythropolis PR4]
gi|229493497|ref|ZP_04387282.1| riboflavin biosynthesis protein ribBA [Rhodococcus erythropolis
SK121]
gi|259585625|sp|C0ZZE5.1|RIBBA_RHOE4 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|226185626|dbj|BAH33730.1| riboflavin biosynthesis bifunctional protein RibA [Rhodococcus
erythropolis PR4]
gi|229319458|gb|EEN85294.1| riboflavin biosynthesis protein ribBA [Rhodococcus erythropolis
SK121]
Length=424
Score = 262 bits (670), Expect = 5e-68, Method: Compositional matrix adjust.
Identities = 163/368 (45%), Positives = 218/368 (60%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G +C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGDDC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD R G GTGISASDRA T+ LA+ S A DF RPG
Sbjct 67 DRLGLPPMYATNQDKHGTAYTVTVDAREGIGTGISASDRAATMRLLANPESGANDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A+ RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKEGGVLRRPGHTEAAVDLARMADLRPAGVICEIVSQKDEGAMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA++SI +L+A+RR+ E V+R A +PT G +G+ +YD EH+A++ G +
Sbjct 187 EHNLALISIADLIAWRRKHEKHVLRIAEARIPTRHGEFTAVGYTSIYDEVEHVALVRGDI 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGDVFGS C CG +L+ AL ++ +G GVVLY+R
Sbjct 247 AGPDGDGSDVLVRVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA +D + + IL DLG+ ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGSDTVDANLELGLPADARDYGIGAQILVDLGISSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|343924573|ref|ZP_08764121.1| riboflavin biosynthesis protein RibBA [Gordonia alkanivorans
NBRC 16433]
gi|343765508|dbj|GAA11047.1| riboflavin biosynthesis protein RibBA [Gordonia alkanivorans
NBRC 16433]
Length=437
Score = 261 bits (666), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 165/366 (46%), Positives = 213/366 (59%), Gaps = 36/366 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G C
Sbjct 22 IERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGDAC 81
Query 66 ERLHLPPMCDRD-----TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM + T + V+VD R G GTGISASDRA T+ LA + A DF RPG
Sbjct 82 DRLGLPPMYSMNQDKHGTAYTVTVDAREGIGTGISASDRATTMRLLADPEATAGDFTRPG 141
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA+ PA +CEIVS + MA E FA
Sbjct 142 HVVPLRAKEGGVLRRPGHTEAAVDLARLADLAPAGVICEIVSQKDVGSMARSDELRVFAD 201
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM+SI +L+A+RRR E VVR A +PT G R +G+ VYD EH+A++ G V
Sbjct 202 EHDLAMISIADLIAWRRRHEKHVVRVADARIPTRHGDFRAVGYSSVYDDVEHVALVKGDV 261
Query 240 GA--GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----G 292
+ G V + VH ECLTGDVFGS C CG +L+ A+ ++ +G G++LY+R G
Sbjct 262 SSDDGHDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEMVAEEGRGIILYMRGHEGRGIG 321
Query 293 PAQACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP----- 333
+ DA D + + IL DLGV ++RL + P
Sbjct 322 LLHKLQAYQLQDAGADTVDANLELGLPADSRDYGLGAQILVDLGVSSMRLLTNNPAKRVG 381
Query 334 --GFGL 337
G+GL
Sbjct 382 LDGYGL 387
>gi|257055603|ref|YP_003133435.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Saccharomonospora viridis DSM 43017]
gi|256585475|gb|ACU96608.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase
[Saccharomonospora viridis DSM 43017]
Length=438
Score = 260 bits (665), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 162/371 (44%), Positives = 212/371 (58%), Gaps = 36/371 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G VV+ D + +G L+FAA+ ATP L+AF VR+TSGY+ VAL G +C
Sbjct 15 IERAIEDIANGRPVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICVALTGEDC 74
Query 66 ERLHLPPMCD-----RDTTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R T + V+VD G GTGISA+DR TI LA S A+D RPG
Sbjct 75 DRLDLPPMYHSNQDRRGTAYTVTVDAAEGIGTGISATDRCHTIRLLADPNSKASDLTRPG 134
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A PA LCEIVS N MA E FA
Sbjct 135 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLAPAGVLCEIVSQKNEGDMARRDELEVFAA 194
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H L +++I +L+AYR+R E QV R A +P AG R IG+ + D EH+A + G +
Sbjct 195 DHDLQLITIADLIAYRKRREKQVERVAEARIPLAAGTFRAIGYDSLLDGIEHVAFVYGDI 254
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGL 299
G G + + VH ECLTGDVFGS C CG +L AL ++ +G GVVLY+R + GL
Sbjct 255 GDGEDILVRVHSECLTGDVFGSLRCDCGPQLQAALKAVADEGRGVVLYVRGH-EGRGIGL 313
Query 300 FAR------GDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP------ 333
+ DA D + + IL DLGV ++RL + P
Sbjct 314 LHKLQAYELQDAGADTVDANLALGVPADARDYGTGAQILSDLGVRSMRLLTNNPAKRVGL 373
Query 334 -GFGLVMFGAI 343
G+GL + G +
Sbjct 374 EGYGLRVVGRV 384
>gi|15608553|ref|NP_215931.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis H37Rv]
gi|15840872|ref|NP_335909.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis CDC1551]
gi|31792609|ref|NP_855102.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium bovis AF2122/97]
65 more sequence titles
gi|121637345|ref|YP_977568.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium bovis BCG str. Pasteur
1173P2]
gi|148661206|ref|YP_001282729.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis H37Ra]
gi|148822635|ref|YP_001287389.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis F11]
gi|167968454|ref|ZP_02550731.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis H37Ra]
gi|224989820|ref|YP_002644507.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
bovis BCG str. Tokyo 172]
gi|253799535|ref|YP_003032536.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
KZN 1435]
gi|254231656|ref|ZP_04924983.1| riboflavin biosynthesis protein ribA2 : GTP cyclohydrolase II
+ 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
tuberculosis C]
gi|254364297|ref|ZP_04980343.1| riboflavin biosynthesis protein ribA2 : GTP cyclohydrolase II
+ 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
tuberculosis str. Haarlem]
gi|254550429|ref|ZP_05140876.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis '98-R604
INH-RIF-EM']
gi|289554795|ref|ZP_06444005.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
KZN 605]
gi|289569432|ref|ZP_06449659.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T17]
gi|289574084|ref|ZP_06454311.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
K85]
gi|289745166|ref|ZP_06504544.1| riboflavin biosynthesis protein ribBA [Mycobacterium tuberculosis
02_1987]
gi|289749973|ref|ZP_06509351.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T92]
gi|289753497|ref|ZP_06512875.1| GTP cyclohydrolase II [Mycobacterium tuberculosis EAS054]
gi|289761574|ref|ZP_06520952.1| GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate
synthase [Mycobacterium tuberculosis GM 1503]
gi|294994977|ref|ZP_06800668.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis 210]
gi|297633971|ref|ZP_06951751.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis KZN
4207]
gi|297730960|ref|ZP_06960078.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis KZN
R506]
gi|306780746|ref|ZP_07419083.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu002]
gi|306784145|ref|ZP_07422467.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu003]
gi|306788515|ref|ZP_07426837.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu004]
gi|306792838|ref|ZP_07431140.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu005]
gi|306803119|ref|ZP_07439787.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu008]
gi|306971706|ref|ZP_07484367.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu010]
gi|307083985|ref|ZP_07493098.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu012]
gi|313658293|ref|ZP_07815173.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis KZN
V2475]
gi|339631482|ref|YP_004723124.1| riboflavin biosynthesis protein RibA [Mycobacterium africanum
GM041182]
gi|61224310|sp|P0A5V0.1|RIBBA_MYCTU RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|61224311|sp|P0A5V1.1|RIBBA_MYCBO RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|166977458|sp|A1KIK4.1|RIBBA_MYCBP RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|166977459|sp|A5U2B7.1|RIBBA_MYCTA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|254797704|sp|C1AN60.1|RIBBA_MYCBT RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|3256018|emb|CAB02199.1| PROBABLE RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBA2 : GTP cyclohydrolase
II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP
synthase) [Mycobacterium tuberculosis H37Rv]
gi|13881072|gb|AAK45723.1| 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase
II [Mycobacterium tuberculosis CDC1551]
gi|31618198|emb|CAD94311.1| PROBABLE RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBA2 : GTP cyclohydrolase
II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP
synthase) [Mycobacterium bovis AF2122/97]
gi|121492992|emb|CAL71463.1| Probable riboflavin biosynthesis protein ribA2 [Mycobacterium
bovis BCG str. Pasteur 1173P2]
gi|124600715|gb|EAY59725.1| riboflavin biosynthesis protein ribA2 : GTP cyclohydrolase II
+ 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
tuberculosis C]
gi|134149811|gb|EBA41856.1| riboflavin biosynthesis protein ribA2 : GTP cyclohydrolase II
+ 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
tuberculosis str. Haarlem]
gi|148505358|gb|ABQ73167.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis H37Ra]
gi|148721162|gb|ABR05787.1| riboflavin biosynthesis protein ribA2: GTP cyclohydrolase II
+ 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
tuberculosis F11]
gi|224772933|dbj|BAH25739.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
bovis BCG str. Tokyo 172]
gi|253321038|gb|ACT25641.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
KZN 1435]
gi|289439427|gb|EFD21920.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
KZN 605]
gi|289538515|gb|EFD43093.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
K85]
gi|289543186|gb|EFD46834.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T17]
gi|289685694|gb|EFD53182.1| riboflavin biosynthesis protein ribBA [Mycobacterium tuberculosis
02_1987]
gi|289690560|gb|EFD57989.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T92]
gi|289694084|gb|EFD61513.1| GTP cyclohydrolase II [Mycobacterium tuberculosis EAS054]
gi|289709080|gb|EFD73096.1| GTP cyclohydrolase II + 3,4-dihydroxy-2-butanone 4-phosphate
synthase [Mycobacterium tuberculosis GM 1503]
gi|308326405|gb|EFP15256.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu002]
gi|308331091|gb|EFP19942.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu003]
gi|308334902|gb|EFP23753.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu004]
gi|308338711|gb|EFP27562.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu005]
gi|308350190|gb|EFP39041.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu008]
gi|308358780|gb|EFP47631.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu010]
gi|308366350|gb|EFP55201.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu012]
gi|323720079|gb|EGB29185.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
CDC1551A]
gi|326903036|gb|EGE49969.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
W-148]
gi|328459283|gb|AEB04706.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
KZN 4207]
gi|339294393|gb|AEJ46504.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis CCDC5079]
gi|339298030|gb|AEJ50140.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis CCDC5180]
gi|339330838|emb|CCC26509.1| putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase
II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP
synthase) [Mycobacterium africanum GM041182]
gi|341601364|emb|CCC64037.1| probable riboflavin biosynthesis protein ribA2 [Mycobacterium
bovis BCG str. Moreau RDJ]
gi|344219245|gb|AEM99875.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium tuberculosis CTRI-2]
Length=425
Score = 260 bits (664), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 165/368 (45%), Positives = 218/368 (60%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TSVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MAH E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ ALA ++ +G GVVLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|308231835|ref|ZP_07413935.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu001]
gi|308375456|ref|ZP_07443983.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu007]
gi|308377722|ref|ZP_07480174.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu009]
gi|308380069|ref|ZP_07488586.2| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu011]
gi|308215908|gb|EFO75307.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu001]
gi|308346238|gb|EFP35089.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu007]
gi|308354831|gb|EFP43682.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu009]
gi|308362717|gb|EFP51568.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
SUMu011]
Length=422
Score = 259 bits (663), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 165/368 (45%), Positives = 218/368 (60%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 4 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 63
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TSVA DF RPG
Sbjct 64 DRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPG 123
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MAH E FA
Sbjct 124 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFAD 183
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 184 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 243
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ ALA ++ +G GVVLY+R
Sbjct 244 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRG 303
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 304 IGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 363
Query 334 ----GFGL 337
G+GL
Sbjct 364 VGLDGYGL 371
>gi|333919549|ref|YP_004493130.1| GTP cyclohydrolase-2 [Amycolicicoccus subflavus DQS3-9A1]
gi|333481770|gb|AEF40330.1| GTP cyclohydrolase-2 [Amycolicicoccus subflavus DQS3-9A1]
Length=422
Score = 258 bits (660), Expect = 8e-67, Method: Compositional matrix adjust.
Identities = 160/370 (44%), Positives = 218/370 (59%), Gaps = 38/370 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RAI +A G AVV+ D + +G L+FAA+ ATP L+AF VR+TSGY+ V L GA+C
Sbjct 7 VERAIADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYVCVPLDGADC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + V+VD + G GTGISA+DR+ T LA + DF RPG
Sbjct 67 DRLGLPPMFATNQDKHQTAYTVTVDAKEGVGTGISAADRSITCQLLADPAARPEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GV+ R G EAAVDL+RLA RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKEGGVMRRAGHTEAAVDLSRLAGLRPAGVICEIVSQKDEGYMAKADELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LAM+SI +L+++RR+ E VVR A +PT G R +GFR +YD EH+A+++G +
Sbjct 187 DHNLAMISIADLISWRRKNEKHVVRVADARIPTPYGEFRAVGFRSIYDEVEHVALVLGDI 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGD+FGS C CG +L+ A+ ++ +G GVVLY+R
Sbjct 247 PGPDGKGTDVLVRVHSECLTGDIFGSLRCDCGPQLDAAMRMVAEEGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA +D + + IL DLGV +RL + P
Sbjct 307 IGLMHKLQAYQLQDAGSDTVDANLALGLPADARDYGIGAQILVDLGVTTMRLLTNNPAKR 366
Query 334 ----GFGLVM 339
G+GL +
Sbjct 367 AGLDGYGLAI 376
>gi|289447011|ref|ZP_06436755.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
CPHL_A]
gi|289419969|gb|EFD17170.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
CPHL_A]
Length=425
Score = 258 bits (660), Expect = 8e-67, Method: Compositional matrix adjust.
Identities = 164/368 (45%), Positives = 217/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TSVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MAH E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAETRIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ ALA ++ +G GVVLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|68536085|ref|YP_250790.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Corynebacterium jeikeium K411]
gi|68263684|emb|CAI37172.1| GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate
synthase [Corynebacterium jeikeium K411]
Length=420
Score = 258 bits (659), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 154/332 (47%), Positives = 204/332 (62%), Gaps = 24/332 (7%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RAI +A G AVV+ D + +G L+FAA+ ATP L+AF VRH+SGY+ V + A+C
Sbjct 17 VERAIADIAAGKAVVVVDDEDRENEGDLIFAAELATPELMAFMVRHSSGYVCVGMDSADC 76
Query 66 ERLHLPPMCDRD-----TTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R+ T + V+VD G TGISA+DRA T+ LA TS A F RPG
Sbjct 77 DRLGLPPMVARNEDVRGTAYTVTVDAAEGVDTGISATDRARTVRLLADPTSTVATFNRPG 136
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R+G EAAVDLAR A PA ALCEIVS ++P MA E FA
Sbjct 137 HVVPLRAKRGGVLVRQGHTEAAVDLARAANLAPAGALCEIVSKEDPTTMARLPELRRFAD 196
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA++SI +L +RR + R LPT G R IG+ ++ D EH+A++ G V
Sbjct 197 EHDLALISIEQLQDWRRHHTQTLERAVETRLPTVHGNFRAIGYVNIIDGTEHVALVKGDV 256
Query 240 -----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPA 294
G+ PVP+ VH ECLTGDVFGS C CG++L+ AL + A+G GVV+YLR
Sbjct 257 SAVSTGSEEPVPVRVHSECLTGDVFGSRRCDCGDQLSAALDYIEAKGRGVVIYLR----- 311
Query 295 QACGLFARGDAATDVMPETVTWILRDLGVYAI 326
G RG ++P+ ++L+D G+ +
Sbjct 312 ---GHEGRG---IGLLPKLRAYVLQDEGLDTV 337
>gi|302525889|ref|ZP_07278231.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Streptomyces sp.
AA4]
gi|302434784|gb|EFL06600.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Streptomyces sp.
AA4]
Length=420
Score = 258 bits (658), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 162/370 (44%), Positives = 210/370 (57%), Gaps = 34/370 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V AI +A G AVV+ D + +G L+FAA+ ATP L+AF VR+TSGY+ V L AE
Sbjct 4 VEAAIADIAAGRAVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICVPLTEAEA 63
Query 66 ERLHLPPMCD-----RDTTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R T + V+VD G TGISA DRA TI LA + A DF+RPG
Sbjct 64 DRLDLPPMFHTNQDARGTAYSVTVDAAEGISTGISAVDRAHTIRLLADPEATAKDFRRPG 123
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAA+DLARLA PA LCEIVS + MA E FA
Sbjct 124 HVVPLRAKEGGVLRRPGHTEAAIDLARLAGLHPAGVLCEIVSQKDEGDMARRDELEVFAA 183
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H L ++SI EL+AYRRR E QV R A +P AG R +G+ + D EH+A + G +
Sbjct 184 DHDLKIISIAELIAYRRRTEKQVERVAEARIPLAAGTFRAVGYDSLLDGIEHVAFVYGEI 243
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G + + VH ECLTGDVFGS C CG +L+ AL +++ +G GVVLY+R G
Sbjct 244 GDGEDILVRVHSECLTGDVFGSLRCDCGPQLDAALQKVADEGRGVVLYIRGHEGRGIGLL 303
Query 295 QACGLFARGDAATDVMPETV--------------TWILRDLGVYAIRLSDDVP------- 333
+ DA D + + IL DLGV ++RL + P
Sbjct 304 HKLQAYQLQDAGADTVDANLALGVPADARDYGTGAQILCDLGVRSMRLLTNNPAKRVGLE 363
Query 334 GFGLVMFGAI 343
G+GL + G +
Sbjct 364 GYGLRVTGRV 373
>gi|330466991|ref|YP_004404734.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Verrucosispora maris AB-18-032]
gi|328809962|gb|AEB44134.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Verrucosispora maris AB-18-032]
Length=426
Score = 257 bits (657), Expect = 2e-66, Method: Compositional matrix adjust.
Identities = 164/368 (45%), Positives = 217/368 (59%), Gaps = 36/368 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ +A+ +A G VV+ DP+ +G L+FAA+ ATP L+AF VRHTSG++ V L EC
Sbjct 13 IEQALAEIAAGRPVVVVDDPDRENEGDLIFAAELATPELLAFTVRHTSGFICVPLTEDEC 72
Query 66 ERLHLPPMCD-----RDTTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R T + V+VD R G TGISA+DRA TI LA ++ AD RPG
Sbjct 73 DRLDLPPMHHTNQDRRQTAYTVTVDAREGVSTGISAADRAHTIRLLADPSTGPADLARPG 132
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA RPA LCE+V+ D M + +F
Sbjct 133 HVVPLRARPGGVLRRAGHTEAAVDLARLAGLRPAGVLCELVNDDG--SMMRLPDLEKFCA 190
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+++I +L+AYRRRIE QV A +PT G R +G+R D EH+A+++G +
Sbjct 191 EHSLALITIADLIAYRRRIEKQVELVADARMPTEHGVFRALGYRSETDSAEHVALVMGDI 250
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPG------- 292
G G V + VH ECLTGD F S C CG +LN AL R++ +G GVVLY+R
Sbjct 251 GDGRDVLVRVHSECLTGDAFASVRCDCGPQLNAALDRVAKEGRGVVLYVRGHEGRGIGLL 310
Query 293 -PAQACGLFARG----DAATDV-MPE------TVTWILRDLGVYAIRLSDDVP------- 333
QA L +G DA D+ +P T IL D+GV ++RL + P
Sbjct 311 HKLQAYQLQDQGRDTVDANLDLGLPADARDYGTGAQILYDIGVRSMRLLTNNPAKRAGLE 370
Query 334 GFGLVMFG 341
G+GL + G
Sbjct 371 GYGLTVTG 378
>gi|340626429|ref|YP_004744881.1| putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase
II + 3,4-dihydroxy-2-butanone 4-phosphate synthase [Mycobacterium
canettii CIPT 140010059]
gi|340004619|emb|CCC43763.1| putative riboflavin biosynthesis protein RIBA2 : GTP cyclohydrolase
II + 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP
synthase) [Mycobacterium canettii CIPT 140010059]
Length=425
Score = 257 bits (656), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 164/368 (45%), Positives = 217/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TSVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ ALA ++ +G GVVLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|169629880|ref|YP_001703529.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium abscessus ATCC 19977]
gi|226739257|sp|B1MCA4.1|RIBBA_MYCA9 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|169241847|emb|CAM62875.1| Putative riboflavin biosynthesis protein RibA2 [Mycobacterium
abscessus]
Length=417
Score = 257 bits (656), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 160/368 (44%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G +C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLAGEDC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L P ++D T + V+VD + G GTGISASDRA T+ LA A S A DF +PG
Sbjct 67 DRLGLLPQYAVNQDKHGTAYTVTVDAKNGIGTGISASDRAATMRLLADAASTADDFTKPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EA+VDLA+LA RPAA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEASVDLAKLAGLRPAAVICEIVSQKDEGAMAQTEELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+VSI +L+ +RR+ E V R A +PT G R +G+ +YD EH+A+++G +
Sbjct 187 EHNLALVSIADLIEWRRKHEKHVQRIAEARIPTQHGEFRAVGYTSIYDDVEHVALVLGDI 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGDVFGS C CG +L+ A+ ++ +G G+VLY+R
Sbjct 247 SGPDGDGNDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMEMVAKEGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGLGAQILVDLGVKSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|289442860|ref|ZP_06432604.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T46]
gi|289415779|gb|EFD13019.1| riboflavin biosynthesis protein ribA2 [Mycobacterium tuberculosis
T46]
Length=397
Score = 256 bits (655), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 149/294 (51%), Positives = 195/294 (67%), Gaps = 12/294 (4%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TSVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MAH E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLR 289
G V + VH ECLTGDVFGS C CG +L+ ALA ++ +G GVVLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300
>gi|41407238|ref|NP_960074.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|81571405|sp|Q741F1.1|RIBBA_MYCPA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|41395589|gb|AAS03457.1| RibA2 [Mycobacterium avium subsp. paratuberculosis K-10]
Length=425
Score = 256 bits (654), Expect = 4e-66, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 216/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TS+A DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|118464982|ref|YP_882547.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium avium 104]
gi|166977457|sp|A0QI09.1|RIBBA_MYCA1 RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|118166269|gb|ABK67166.1| riboflavin biosynthesis protein ribAB [Mycobacterium avium 104]
Length=425
Score = 256 bits (653), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 216/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TS+A DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGFPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|254775811|ref|ZP_05217327.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium avium subsp. avium
ATCC 25291]
gi|336461615|gb|EGO40480.1| GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase
[Mycobacterium avium subsp. paratuberculosis S397]
Length=425
Score = 256 bits (653), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 216/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TS+A DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|118617424|ref|YP_905756.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium ulcerans Agy99]
gi|166977460|sp|A0PPL6.1|RIBBA_MYCUA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|118569534|gb|ABL04285.1| riboflavin biosynthesis protein RibA2 [Mycobacterium ulcerans
Agy99]
Length=425
Score = 254 bits (650), Expect = 1e-65, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ + G AV++ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIGAGKAVIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAVC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD + G GTGISASDRA T+ LA SVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSRKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRRGEFRAIGYTSIYENVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G GVVLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGSQLDAAMAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLLHKLQTYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|296395031|ref|YP_003659915.1| GTP cyclohydrolase II [Segniliparus rotundus DSM 44985]
gi|296182178|gb|ADG99084.1| GTP cyclohydrolase II [Segniliparus rotundus DSM 44985]
Length=414
Score = 254 bits (649), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 159/367 (44%), Positives = 207/367 (57%), Gaps = 36/367 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G AVV+ D +G L FAA+ AT LVAF +RHTSGYL V + +C
Sbjct 7 IERAIKDIADGKAVVVVDDEERENEGDLTFAAEKATSELVAFMIRHTSGYLCVPMEEEDC 66
Query 66 ERLHLPPMCD-----RDTTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R T + V+VD + G GTGISA DRA TI LA + +AD RPG
Sbjct 67 DRLDLPPMYTVNQDRRGTAYTVTVDAKDGVGTGISAKDRAHTIRLLADPRTKSADLTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
H+VP++A+ GV+ R G EAAVDLARLA RP +CEIVS + MA E FA
Sbjct 127 HMVPLRAKPGGVMRRPGHTEAAVDLARLAGLRPVGVICEIVSTKDEEHMAKGDELRVFAE 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA VSI +L+ YRRR E V R A LPT G + IG+ Y+ EH+A++ G +
Sbjct 187 EHNLARVSIADLIRYRRRYEKHVRREAQARLPTRHGVFQSIGYSCAYEDAEHVAMVFGDI 246
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGL 299
G G V + VH ECLTGDVFGS C CG +L+ A+ ++A+G GVVLY+R + GL
Sbjct 247 GDGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAAMEIIAAEGRGVVLYMRGH-EGRGIGL 305
Query 300 FAR------GDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP------ 333
+ D D + + IL DLG+ ++RL + P
Sbjct 306 LHKLRAYELQDGGADTVDANLQLGLPADSRDYGVGAQILVDLGIRSMRLLTNNPAKRVGL 365
Query 334 -GFGLVM 339
G+GL +
Sbjct 366 DGYGLTI 372
>gi|312195563|ref|YP_004015624.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Frankia sp. EuI1c]
gi|311226899|gb|ADP79754.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Frankia sp. EuI1c]
Length=514
Score = 254 bits (649), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 166/364 (46%), Positives = 209/364 (58%), Gaps = 36/364 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V A+ A+ G AVV+ D + +G L+FAA+ ATP LVAF VRHTSG + L E
Sbjct 22 VEDAVAAIRAGRAVVVVDDADRENEGDLIFAAEMATPELVAFMVRHTSGVICAPLTEQET 81
Query 66 ERLHLPPMCDRDTTH-----CVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L M +T VSVD R G TGISA+DRA T+ LA A +V+ D RPG
Sbjct 82 DRLDLGQMVPTNTERMGTAFTVSVDAREGVSTGISAADRAHTLRLLAGAATVSTDLSRPG 141
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
H+ P++A+ GVL R G EAAVDLARLA RPA A+CEIV+ D MA + V FA
Sbjct 142 HIFPLRAREGGVLRRPGHTEAAVDLARLAGLRPAGAICEIVNDDG--TMARLPQLVVFAR 199
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGL ++SI +LVAYRRR E QVVR A+LPT GA R IG+R D EH+A+I G +
Sbjct 200 EHGLVLISIADLVAYRRRTEMQVVRVAEASLPTKYGAFRAIGYRGTLDGVEHVALIRGEI 259
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G V + VH ECLTGDVFGS C CG +L+ AL ++A+G GVVLY+R G
Sbjct 260 GDGAEVLVRVHSECLTGDVFGSLRCDCGAQLDAALRMVAAEGRGVVLYMRGHEGRGIGLM 319
Query 295 QACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP------- 333
+ DA D + + +L DLGV +RL + P
Sbjct 320 HKLAAYQLQDAGHDTVDANLALGLPADARDYGVGAQVLVDLGVRGMRLLTNNPAKRAGLE 379
Query 334 GFGL 337
G+GL
Sbjct 380 GYGL 383
>gi|260578780|ref|ZP_05846687.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Corynebacterium jeikeium ATCC 43734]
gi|258603078|gb|EEW16348.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Corynebacterium jeikeium ATCC 43734]
Length=423
Score = 254 bits (648), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 153/335 (46%), Positives = 202/335 (61%), Gaps = 27/335 (8%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RAI +A G AVV+ D + +G L+FAA+ ATP L+AF VRH+SGY+ V + A+C
Sbjct 17 VERAIADIAAGKAVVVVDDEDRENEGDLIFAAELATPELMAFMVRHSSGYVCVGMDSADC 76
Query 66 ERLHLPPMCDRD-----TTHCVSVDV-RGTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM R+ T + V+VD G TGISA+DRA T+ LA TS A F RPG
Sbjct 77 DRLGLPPMVARNEDVRGTAYTVTVDAAEGVDTGISATDRAHTVRLLADPTSTATAFNRPG 136
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R+G EAAVDLAR A PA LCEIVS ++P MA E FA
Sbjct 137 HVVPLRAKRGGVLVRQGHTEAAVDLARAANLAPAGVLCEIVSEEDPTTMARLPELRRFAD 196
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA++SI +L +RR + R LPT G R IG+ ++ D EH+A++ G V
Sbjct 197 EHDLALISIEQLQDWRRHHTQTLERAVETRLPTVHGNFRAIGYVNIIDGTEHVALVKGDV 256
Query 240 GAG--------VPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP 291
A PVP+ VH ECLTGDVFGS C CG++L+ AL + A+G GVV+YLR
Sbjct 257 SAAGATSADSEEPVPVRVHSECLTGDVFGSRRCDCGDQLSAALDYIEAKGRGVVIYLR-- 314
Query 292 GPAQACGLFARGDAATDVMPETVTWILRDLGVYAI 326
G RG ++P+ ++L+D G+ +
Sbjct 315 ------GHEGRG---IGLLPKLRAYVLQDEGLDTV 340
>gi|342858708|ref|ZP_08715363.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium colombiense CECT
3035]
gi|342134412|gb|EGT87592.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium colombiense CECT
3035]
Length=425
Score = 253 bits (647), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 214/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L G C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGEIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA TS A DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARRGVGTGISASDRATTMRLLADPTSAADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLAMITIADLIEWRRKHEKHIARIAEARIPTRHGEFRAIGYASIYEEVEHVALVRGDI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|254822409|ref|ZP_05227410.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium intracellulare ATCC
13950]
Length=425
Score = 253 bits (647), Expect = 3e-65, Method: Compositional matrix adjust.
Identities = 160/368 (44%), Positives = 216/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AV++ D + +G L+FAA+ ATP +VAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD + G GTGISASDRA T+ LA+ SVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDAKDGVGTGISASDRATTMRLLANPISVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LAM++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLAMITIADLIEWRRKHEKHIARIAEARIPTRHGEFRAIGYASIYEEVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPDSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|15827210|ref|NP_301473.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium leprae TN]
gi|221229688|ref|YP_002503104.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium leprae Br4923]
gi|13092758|emb|CAC30067.1| putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate
synthase [Mycobacterium leprae]
gi|219932795|emb|CAR70652.1| putative GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate
synthase [Mycobacterium leprae Br4923]
Length=435
Score = 253 bits (646), Expect = 3e-65, Method: Compositional matrix adjust.
Identities = 163/368 (45%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AVV+ D + +G L+FAA+ AT +VAF VR+TSGYL L GA C
Sbjct 17 VERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATLEMVAFMVRYTSGYLCAPLDGAIC 76
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA SVA DF RPG
Sbjct 77 DRLGLLPMFAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPASVADDFTRPG 136
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA +PA A+CEIVS + MA E FA
Sbjct 137 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 196
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAV----I 235
EH LA+++I +L+A+RR+ E + R A +PT G R IG+ +YD +H+A+ I
Sbjct 197 EHDLALITIADLIAWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYDDVKHVALVRGEI 256
Query 236 VGAVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G+ G G + + VH ECLTGDVFGS C CG +L+ A+A ++ +G GVVLY+R
Sbjct 257 AGSSGDGDDILVRVHSECLTGDVFGSRRCDCGTQLDAAMAMVAREGRGVVLYMRGHEGRG 316
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 317 IGLMHKLQAYQLQDAGADTVDANIKLGFPSDARDYGIGAQILVDLGVRSMRLLTNNPAKR 376
Query 334 ----GFGL 337
G+GL
Sbjct 377 VGLDGYGL 384
>gi|319948955|ref|ZP_08023060.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Dietzia cinnamea P4]
gi|319437393|gb|EFV92408.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Dietzia cinnamea P4]
Length=422
Score = 253 bits (646), Expect = 4e-65, Method: Compositional matrix adjust.
Identities = 161/353 (46%), Positives = 207/353 (59%), Gaps = 27/353 (7%)
Query 8 VRRAITAMAGGHAVVL--TGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RAI +A G AVV+ + D +G L+FAA+ ATP L+ F VR++SGY+ VAL +C
Sbjct 7 IERAIADIAAGRAVVVVDSEDRENEGDLIFAAELATPELMGFLVRYSSGYVCVALEPEDC 66
Query 66 ERLHLPPM----CDR-DTTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
RL LPPM DR DT + V+VD R G TGISA+DRA T LA+ +V DF RPG
Sbjct 67 LRLDLPPMRAINEDRHDTAYTVTVDARTGVSTGISAADRARTARLLAADDTVPGDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA RPA +CEIVS D+P MA E FA
Sbjct 127 HVVPLRARPGGVLTRPGHTEAAVDLARLAGLRPAGVICEIVSEDDPTTMARTPELRRFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLAMV+I L A+RR E QVV AA +PT AG G+RD EH+A++ G +
Sbjct 187 EHGLAMVTIEALQAWRRAHEVQVVHEAAARVPTPAGTLTAHGYRDTLQGVEHVAMVAGDI 246
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
PV + +H ECLTGDVF S C CG +L+ A+A + +G G+VLY+R G
Sbjct 247 SGDEPVSVRIHSECLTGDVFHSLRCDCGPQLDAAVAAVCEEGRGIVLYMRGHEGRGIGLV 306
Query 295 QACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP 333
Q + D+ D + + +LRDLGV +RL + P
Sbjct 307 QKLRAYQLQDSGRDTVDANLDLGLPADARDFSLAAQMLRDLGVTRVRLMTNNP 359
>gi|183982235|ref|YP_001850526.1| riboflavin biosynthesis protein RibA2 [Mycobacterium marinum
M]
gi|226739258|sp|B2HP67.1|RIBBA_MYCMM RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|183175561|gb|ACC40671.1| riboflavin biosynthesis protein RibA2 [Mycobacterium marinum
M]
Length=425
Score = 253 bits (645), Expect = 4e-65, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ + G AV++ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIGAGKAVIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAVC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD + G GTGISASDRA T+ LA SVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAEDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G GVVLY+R
Sbjct 247 AGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLLHKLQAYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|240172788|ref|ZP_04751447.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium kansasii ATCC 12478]
Length=428
Score = 253 bits (645), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 162/368 (45%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G A+++ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G+ C
Sbjct 7 VERAVADIAAGKAIIVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGSIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ LA S A DF RPG
Sbjct 67 DRLGLLPMFAVNQDKHGTAYTVTVDARQGIGTGISASDRATTMRLLADPASNADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGAMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EHGLA+++I +L+ +RR+ E V R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHGLALITIADLIEWRRKHEKHVERIAEARIPTRHGEFRAIGYSSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G GVVLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|256379225|ref|YP_003102885.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Actinosynnema
mirum DSM 43827]
gi|255923528|gb|ACU39039.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Actinosynnema
mirum DSM 43827]
Length=417
Score = 252 bits (644), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 164/364 (46%), Positives = 211/364 (58%), Gaps = 34/364 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G V++ D + +G L+FAA+ ATP LVAF VRHTSGY+ V+L A+C
Sbjct 7 IERAVADVAAGRPVIVVDDEDRENEGDLIFAAEKATPELVAFMVRHTSGYICVSLTEADC 66
Query 66 ERLHLPPMC-----DRDTTHCVSVDVRGTGT-GISASDRAWTIAALASATSVAADFQRPG 119
RL LPPM +R T + V+VD + GT GISA+DRA TI LA AT+ A F RPG
Sbjct 67 VRLDLPPMYHTNQDERGTAYAVTVDAKQGGTTGISAADRARTIRLLADATATPAHFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDL+RLA P LCEIVS + MA E FA
Sbjct 127 HVVPLRARDGGVLRRTGHTEAAVDLSRLAGLAPVGVLCEIVSQKDEGDMAQREELEVFAA 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+++I +LVAYRRR+E QV R A +PT G R G+ D EH+A++ G V
Sbjct 187 EHDLALITIADLVAYRRRVEVQVQRVAEARIPTAHGVFRAYGYDSKVDGIEHVALVCGEV 246
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G V + VH ECLTGDV GS C CG +L+ ALA ++A+G GVVLY+R G
Sbjct 247 GDGEEVLVRVHSECLTGDVLGSLRCDCGPQLDAALAAVAAEGRGVVLYMRGHEGRGIGLV 306
Query 295 QACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP------- 333
+ DA D + + IL DLGV ++RL + P
Sbjct 307 HKLQAYQLQDAGADTVDANLDLGLPADARDYGTGAQILVDLGVRSMRLLTNNPAKRVGLE 366
Query 334 GFGL 337
G+GL
Sbjct 367 GYGL 370
>gi|296170720|ref|ZP_06852294.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295894624|gb|EFG74359.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=425
Score = 252 bits (644), Expect = 6e-65, Method: Compositional matrix adjust.
Identities = 161/368 (44%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA C
Sbjct 7 VERAVADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD R G GTGISASDRA T+ L+ SVA DF RPG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLSDPASVADDFTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA+++I +L+ +RR+ E + R A +PT G R IG+ +Y+ EH+A++ G +
Sbjct 187 EHDLALITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYASIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVTW--------------ILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|118470936|ref|YP_887388.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium smegmatis str. MC2
155]
gi|118172223|gb|ABK73119.1| riboflavin biosynthesis protein ribAB [Mycobacterium smegmatis
str. MC2 155]
Length=439
Score = 251 bits (642), Expect = 9e-65, Method: Compositional matrix adjust.
Identities = 160/368 (44%), Positives = 216/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RAI +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L G C
Sbjct 7 VERAIADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGEIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD + GTGISASDRA T+ ALA+ SVA DF +PG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDAKKDVGTGISASDRATTMRALANPGSVADDFTKPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA +PA A+CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGAICEIVSQKDEGDMARTDELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +L+ +RR+ E + R A +PT G R +G++ +Y+ EH+A++ G +
Sbjct 187 DHDLALISIADLIEWRRKHEKHIERIAEARIPTRHGEFRAVGYKSIYEDVEHVALVRGEI 246
Query 240 GA----GVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G GVVLY+R
Sbjct 247 SGPGSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLG+ ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGEDTVDANLKLGLPADARDYGIGAQILVDLGIRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|108799357|ref|YP_639554.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium sp. MCS]
gi|119868473|ref|YP_938425.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium sp. KMS]
gi|126435015|ref|YP_001070706.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Mycobacterium sp. JLS]
gi|108769776|gb|ABG08498.1| GTP cyclohydrolase II [Mycobacterium sp. MCS]
gi|119694562|gb|ABL91635.1| GTP cyclohydrolase II [Mycobacterium sp. KMS]
gi|126234815|gb|ABN98215.1| GTP cyclohydrolase II [Mycobacterium sp. JLS]
Length=439
Score = 251 bits (642), Expect = 9e-65, Method: Compositional matrix adjust.
Identities = 163/368 (45%), Positives = 215/368 (59%), Gaps = 38/368 (10%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
V RAI +A G AVV+ D + +G L+FAA+ ATP LVAF VR+TSGYL V L GA C
Sbjct 7 VERAIADIAAGKAVVVIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAIC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL L PM ++D T + V+VD + G GTGISASDRA T+ LA TS A +F +PG
Sbjct 67 DRLGLLPMYAVNQDKHGTAYTVTVDAKHGVGTGISASDRATTMRLLADPTSNADEFTKPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLARLA +PA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARLAGLQPAGTICEIVSQKDEGAMAQTDELRIFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
EH LA++SI +L+ +RR+ E + R A +PT G R +G+ +YD EH+A++ G V
Sbjct 187 EHDLALISIADLIEWRRKHERHIERIAEARIPTRHGEFRAVGYTSIYDDVEHVALVRGDV 246
Query 240 ----GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP---- 291
G G V + VH ECLTGDVFGS C CG +L+ A+A ++ +G G+VLY+R
Sbjct 247 AGPHGDGHDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRG 306
Query 292 -GPAQACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP--- 333
G + DA D + + IL DLGV ++RL + P
Sbjct 307 IGLMHKLQAYQLQDAGDDTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKR 366
Query 334 ----GFGL 337
G+GL
Sbjct 367 VGLDGYGL 374
>gi|54025570|ref|YP_119812.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
cyclohydrolase II protein [Nocardia farcinica IFM 10152]
gi|81602604|sp|Q5YTP3.1|RIBBA_NOCFA RecName: Full=Riboflavin biosynthesis protein ribBA; Includes:
RecName: Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
Short=DHBP synthase; Includes: RecName: Full=GTP cyclohydrolase-2;
AltName: Full=GTP cyclohydrolase II
gi|54017078|dbj|BAD58448.1| putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase
II [Nocardia farcinica IFM 10152]
Length=414
Score = 251 bits (641), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 159/366 (44%), Positives = 217/366 (60%), Gaps = 34/366 (9%)
Query 8 VRRAITAMAGGHAVVLTGDPN--GDGYLVFAAQAATPRLVAFAVRHTSGYLRVALPGAEC 65
+ RA+ +A G AVV+ D + +G L+FAA+ ATP LVAF +R+TSGY+ V L G +C
Sbjct 7 IERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMIRYTSGYICVPLTGEDC 66
Query 66 ERLHLPPM--CDRD---TTHCVSVDVR-GTGTGISASDRAWTIAALASATSVAADFQRPG 119
+RL LPPM ++D T + VSVD R G TGISA+DRA T+ LA A + A D RPG
Sbjct 67 DRLGLPPMYATNQDKHGTAYTVSVDAREGITTGISAADRATTMRLLADADAKADDLTRPG 126
Query 120 HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV 179
HVVP++A+ GVL R G EAAVDLAR+A RPA +CEIVS + MA E FA
Sbjct 127 HVVPLRAKDGGVLRRPGHTEAAVDLARMAGLRPAGVICEIVSQKDEGHMARTEELRVFAD 186
Query 180 EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV 239
+H LA++SI +++A+RR+ E QVVR A +PT GA +G++ +YD EH+A++ G +
Sbjct 187 DHDLALISIADMIAWRRKHEKQVVRVAEARIPTAHGAFTAVGYQSIYDDVEHVALVRGDI 246
Query 240 GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPP-----GPA 294
G G V + VH ECLTGDVFGS C CG +L+ AL + +G GVVLY+R G
Sbjct 247 GDGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAALEMVDQEGRGVVLYMRGHEGRGIGLM 306
Query 295 QACGLFARGDAATDVMPETVT--------------WILRDLGVYAIRLSDDVP------- 333
+ D+ D + + IL DLG+ ++RL + P
Sbjct 307 HKLQAYQLQDSGRDTVDANLDLGLPADARDYGTGAQILVDLGIRSMRLLTNNPAKRVGLD 366
Query 334 GFGLVM 339
G+GL +
Sbjct 367 GYGLTI 372
Lambda K H
0.322 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 657685396884
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40