BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1963c Length=406 Score E Sequences producing significant alignments: (Bits) Value gi|15609100|ref|NP_216479.1| transcriptional repressor (probably... 811 0.0 gi|254550982|ref|ZP_05141429.1| tetR-family transcriptional repr... 809 0.0 gi|340626972|ref|YP_004745424.1| putative transcriptional repres... 808 0.0 gi|323719528|gb|EGB28654.1| tetR-family transcriptional represso... 772 0.0 gi|289570051|ref|ZP_06450278.1| tetR-family transcriptional repr... 732 0.0 gi|183982877|ref|YP_001851168.1| TetR family transcriptional reg... 686 0.0 gi|118618300|ref|YP_906632.1| TetR family transcriptional regula... 679 0.0 gi|120404948|ref|YP_954777.1| TetR family transcriptional regula... 553 2e-155 gi|326330418|ref|ZP_08196726.1| TetR-family transcriptional regu... 191 3e-46 gi|111020231|ref|YP_703203.1| transcriptional regulator [Rhodoco... 187 2e-45 gi|226308415|ref|YP_002768375.1| TetR family transcriptional reg... 182 1e-43 gi|257056996|ref|YP_003134828.1| transcriptional regulator [Sacc... 181 2e-43 gi|229491761|ref|ZP_04385582.1| transcriptional regulator, TetR ... 176 8e-42 gi|229488384|ref|ZP_04382250.1| transcriptional regulator, TetR ... 176 8e-42 gi|134099935|ref|YP_001105596.1| TetR family transcriptional reg... 174 2e-41 gi|312137891|ref|YP_004005227.1| tetr family transcriptional reg... 168 1e-39 gi|111019999|ref|YP_702971.1| transcriptional regulator [Rhodoco... 168 1e-39 gi|325673342|ref|ZP_08153034.1| transcriptional regulator [Rhodo... 168 1e-39 gi|226361784|ref|YP_002779562.1| TetR family transcriptional reg... 167 3e-39 gi|333921631|ref|YP_004495212.1| TetR family transcriptional reg... 166 7e-39 gi|336178035|ref|YP_004583410.1| regulatory protein TetR [Franki... 166 9e-39 gi|326381889|ref|ZP_08203582.1| TetR family transcriptional regu... 156 7e-36 gi|226365579|ref|YP_002783362.1| TetR family transcriptional reg... 154 4e-35 gi|111023076|ref|YP_706048.1| transcriptional regulator [Rhodoco... 153 6e-35 gi|300789712|ref|YP_003770003.1| TetR family transcriptional reg... 149 1e-33 gi|302529939|ref|ZP_07282281.1| predicted protein [Streptomyces ... 147 3e-33 gi|343924408|ref|ZP_08763957.1| putative TetR family transcripti... 147 3e-33 gi|229494482|ref|ZP_04388245.1| transcriptional regulator, TetR ... 139 1e-30 gi|183980756|ref|YP_001849047.1| putative regulatory protein [My... 139 1e-30 gi|302866624|ref|YP_003835261.1| regulatory protein TetR [Microm... 137 4e-30 gi|229494286|ref|ZP_04388049.1| transcriptional regulator, TetR ... 136 5e-30 gi|262204323|ref|YP_003275531.1| TetR family transcriptional reg... 136 5e-30 gi|315503032|ref|YP_004081919.1| regulatory protein TetR [Microm... 136 7e-30 gi|343924104|ref|ZP_08763667.1| putative TetR family transcripti... 135 9e-30 gi|126433161|ref|YP_001068852.1| TetR family transcriptional reg... 135 1e-29 gi|333989495|ref|YP_004522109.1| TetR family transcriptional reg... 135 1e-29 gi|118618877|ref|YP_907209.1| putative regulatory protein [Mycob... 135 1e-29 gi|86741171|ref|YP_481571.1| TetR family transcriptional regulat... 135 1e-29 gi|226304140|ref|YP_002764098.1| TetR family transcriptional reg... 135 2e-29 gi|119866625|ref|YP_936577.1| TetR family transcriptional regula... 135 2e-29 gi|108797539|ref|YP_637736.1| TetR family transcriptional regula... 134 2e-29 gi|288919455|ref|ZP_06413787.1| transcriptional regulator, TetR ... 134 3e-29 gi|118469469|ref|YP_885218.1| TetR family transcriptional regula... 133 6e-29 gi|54022691|ref|YP_116933.1| putative transcriptional regulator ... 132 1e-28 gi|297189980|ref|ZP_06907378.1| TetR family transcriptional regu... 132 1e-28 gi|262203022|ref|YP_003274230.1| TetR family transcriptional reg... 132 1e-28 gi|333920318|ref|YP_004493899.1| TetR family transcriptional reg... 132 2e-28 gi|120401734|ref|YP_951563.1| TetR family transcriptional regula... 130 3e-28 gi|145220791|ref|YP_001131469.1| TetR family transcriptional reg... 130 4e-28 gi|315442433|ref|YP_004075312.1| TetR family transcriptional reg... 129 6e-28 >gi|15609100|ref|NP_216479.1| transcriptional repressor (probably TETR-family) MCE3R [Mycobacterium tuberculosis H37Rv] gi|15841435|ref|NP_336472.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31793155|ref|NP_855648.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97] 72 more sequence titles Length=406 Score = 811 bits (2095), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/406 (100%), Positives = 406/406 (100%), Gaps = 0/406 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL Sbjct 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN Sbjct 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL Sbjct 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 Query 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA Sbjct 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 >gi|254550982|ref|ZP_05141429.1| tetR-family transcriptional repressor mce3R [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=406 Score = 809 bits (2090), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/406 (99%), Positives = 405/406 (99%), Gaps = 0/406 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAV SRALTVLWQREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVTSRALTVLWQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL Sbjct 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN Sbjct 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL Sbjct 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 Query 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA Sbjct 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 >gi|340626972|ref|YP_004745424.1| putative transcriptional repressor (probably TETR-family) MCE3R [Mycobacterium canettii CIPT 140010059] gi|340005162|emb|CCC44311.1| putative transcriptional repressor (probably TETR-family) MCE3R [Mycobacterium canettii CIPT 140010059] Length=406 Score = 808 bits (2086), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/406 (99%), Positives = 405/406 (99%), Gaps = 0/406 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL Sbjct 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN Sbjct 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQA QRLRGLV+ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQATQRLRGLVE 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL Sbjct 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 Query 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA Sbjct 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA 406 >gi|323719528|gb|EGB28654.1| tetR-family transcriptional repressor mce3R [Mycobacterium tuberculosis CDC1551A] gi|339294888|gb|AEJ46999.1| transcriptional repressor (probably TETR-family) MCE3R [Mycobacterium tuberculosis CCDC5079] gi|339298511|gb|AEJ50621.1| transcriptional repressor (probably TETR-family) MCE3R [Mycobacterium tuberculosis CCDC5180] Length=387 Score = 772 bits (1993), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/387 (99%), Positives = 387/387 (100%), Gaps = 0/387 (0%) Query 20 LDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRL 79 +DQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRL Sbjct 1 MDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRL 60 Query 80 TEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMR 139 TEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMR Sbjct 61 TEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMR 120 Query 140 DSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCE 199 DSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCE Sbjct 121 DSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCE 180 Query 200 LPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSF 259 LPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSF Sbjct 181 LPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSF 240 Query 260 SSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTE 319 SSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTE Sbjct 241 SSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTE 300 Query 320 LSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLT 379 LSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLT Sbjct 301 LSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLT 360 Query 380 RYAGVADEISGLALAILTSGAGNLLRA 406 RYAGVADEISGLALAILTSGAGNLLRA Sbjct 361 RYAGVADEISGLALAILTSGAGNLLRA 387 Score = 43.1 bits (100), Expect = 0.075, Method: Compositional matrix adjust. Identities = 34/128 (27%), Positives = 55/128 (43%), Gaps = 20/128 (15%) Query 15 RKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALL------------ 62 R + +L LF +G+ +V +I + AG+ LYR + +KQA+L Sbjct 200 RYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRC 259 Query 63 ---AEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYL 119 A+R Q Q R L +G ++ D DL+A +V + + R+ Sbjct 260 LECIRALRANQQAAQRLRGLVQGHVR-----ISLDAPDLVAVSVTELSHASVEVRDGYLR 314 Query 120 NEDDRTAV 127 N+ DR AV Sbjct 315 NQGDREAV 322 >gi|289570051|ref|ZP_06450278.1| tetR-family transcriptional repressor mce3R [Mycobacterium tuberculosis T17] gi|289543805|gb|EFD47453.1| tetR-family transcriptional repressor mce3R [Mycobacterium tuberculosis T17] Length=443 Score = 732 bits (1889), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/371 (99%), Positives = 368/371 (99%), Gaps = 0/371 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL Sbjct 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN Sbjct 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL Sbjct 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 Query 361 LVAAAISFIED 371 LVAAA+ + + Sbjct 361 LVAAALGWTSE 371 >gi|183982877|ref|YP_001851168.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183176203|gb|ACC41313.1| transcriptional repressor (probably TetR-family) Mce3R [Mycobacterium marinum M] Length=400 Score = 686 bits (1771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/398 (87%), Positives = 364/398 (92%), Gaps = 0/398 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 M SV PVRRRPKDRK+QIL+QAVGLFI+RGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MDSVVAPVRRRPKDRKQQILEQAVGLFIDRGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGE EPTPRPL+ DL DLIAAAVASR+LTVLWQREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGEQEPTPRPLSVDLPDLIAAAVASRSLTVLWQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 + DR VRRRINAIVAGMR+SVLLEVP LSP HSELRAWAVSSTLTSLGRHSL+LP EEL Sbjct 121 DADRIEVRRRINAIVAGMRESVLLEVPGLSPAHSELRAWAVSSTLTSLGRHSLTLPAEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 K+ LYQACMAAARTPPVCEL PL RD DVLFSRYETLLA GARLFRAQGYPAV+ Sbjct 181 KERLYQACMAAARTPPVCELEPLGTAAGGRDGQDVLFSRYETLLATGARLFRAQGYPAVS 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWR LECIRALRAN+QAAQRLRGLV+ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRSLECIRALRANRQAAQRLRGLVE 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAV VTEL+HAS +VRDGYLRNQ DR+ +WIDLIG+LVP TS + RL Sbjct 301 GHVRISLDAPDLVAVCVTELNHASGDVRDGYLRNQADRDTLWIDLIGELVPQTSSVEARL 360 Query 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTS 398 LVAAAISFIEDVARTWHLTRYA VADEI+ +AL+ILTS Sbjct 361 LVAAAISFIEDVARTWHLTRYAAVADEITAIALSILTS 398 >gi|118618300|ref|YP_906632.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118570410|gb|ABL05161.1| transcriptional repressor (probably TetR-family) Mce3R [Mycobacterium ulcerans Agy99] Length=400 Score = 679 bits (1752), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/398 (86%), Positives = 362/398 (91%), Gaps = 0/398 (0%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 M SV PVRRRPKDRK+QIL+QAVGLFI+RGFHSVKLEDIAEAAGVTARALYRHYDNKQA Sbjct 1 MDSVVAPVRRRPKDRKQQILEQAVGLFIDRGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 Query 61 LLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 LLAEAIRTGQDQYQSARRLTEGE EPTPRPL+ DL DLIAAAVASR+LTVL QREARYLN Sbjct 61 LLAEAIRTGQDQYQSARRLTEGEQEPTPRPLSVDLPDLIAAAVASRSLTVLSQREARYLN 120 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEEL 180 + DR VRRRINAIVAGMR+SVLLEVP LSP HSELRAWAVSSTLTSLGRHSL+LP EEL Sbjct 121 DADRIEVRRRINAIVAGMRESVLLEVPGLSPAHSELRAWAVSSTLTSLGRHSLTLPAEEL 180 Query 181 KKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 K+ LYQACMAAARTPPVCEL PL RD DVLFSRYETLLA GARLFRAQGYPAV+ Sbjct 181 KERLYQACMAAARTPPVCELEPLGTAAGGRDGQDVLFSRYETLLATGARLFRAQGYPAVS 240 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWR LECIRALRAN+QAAQRLRGLV+ Sbjct 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRSLECIRALRANRQAAQRLRGLVE 300 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRL 360 GHVRISLDAPDLVAV TEL+HAS +VRDGYLRNQ DR+ +WIDLIG+LVP TS + RL Sbjct 301 GHVRISLDAPDLVAVCATELNHASGDVRDGYLRNQADRDTLWIDLIGELVPQTSSVEARL 360 Query 361 LVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTS 398 LVAAAISFIEDVARTWHLTRYA VADEI+ +AL+ILTS Sbjct 361 LVAAAISFIEDVARTWHLTRYAAVADEITEIALSILTS 398 >gi|120404948|ref|YP_954777.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119957766|gb|ABM14771.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=391 Score = 553 bits (1424), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 285/391 (73%), Positives = 324/391 (83%), Gaps = 3/391 (0%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK+QILDQAV LFI+RGFHSVKLEDIAEA+GVTARALYRHYDNKQALLA AIR Sbjct 2 VRRRPKDRKQQILDQAVRLFIDRGFHSVKLEDIAEASGVTARALYRHYDNKQALLAAAIR 61 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAV 127 GQ+QYQSAR GE E R L+A+L DL+ AAVASR+LTVLWQREARYL+ +R V Sbjct 62 AGQEQYQSARPPAGGEAESPHRALSAELPDLVTAAVASRSLTVLWQREARYLDAAERAEV 121 Query 128 RRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQA 187 RRRI+AIV G+ S+ +EVPDLSP+H+ELRAWAVSS +TSLGRHSL+L +EL +LL+ A Sbjct 122 RRRIHAIVTGIEQSLRVEVPDLSPRHAELRAWAVSSVITSLGRHSLTLAKDELHRLLFGA 181 Query 188 CMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKG 247 CMA ARTPPV PL A ++ LFSR+ETLLAAGARLFRAQGYPAV+TSEIGKG Sbjct 182 CMAVARTPPVG---PLEPDVAPPNDERALFSRHETLLAAGARLFRAQGYPAVSTSEIGKG 238 Query 248 AGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISL 307 GIAGPGLYRSFSSKQAILDALI RLDEW L CIR LR + +AA+ LR LV G V+ISL Sbjct 239 VGIAGPGLYRSFSSKQAILDALITRLDEWWSLACIRVLRTDTEAAECLRALVAGRVQISL 298 Query 308 DAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAIS 367 D PDLVA+SVTELS AS EVRD Y+RNQ DREAVWI+LIGKLVP T+ A+ RLLV AA S Sbjct 299 DDPDLVAMSVTELSFASEEVRDRYMRNQADREAVWIELIGKLVPQTAPAEARLLVGAANS 358 Query 368 FIEDVARTWHLTRYAGVADEISGLALAILTS 398 FI+D RTWHLTRYAG+ADEI+ + L+ILTS Sbjct 359 FIDDAVRTWHLTRYAGIADEITAITLSILTS 389 >gi|326330418|ref|ZP_08196726.1| TetR-family transcriptional regulator [Nocardioidaceae bacterium Broad-1] gi|325951693|gb|EGD43725.1| TetR-family transcriptional regulator [Nocardioidaceae bacterium Broad-1] Length=398 Score = 191 bits (484), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 130/391 (34%), Positives = 196/391 (51%), Gaps = 16/391 (4%) Query 11 RPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQ 70 RP+DRK++I++ A LF GFH+V IA G+TA ALYRH+ KQ LL+ A+ G Sbjct 15 RPRDRKQRIVEVAGHLFYRHGFHNVSTSQIAAEVGITAGALYRHFKGKQDLLSHALTDGF 74 Query 71 DQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRR 130 DQ + R + EG +P L + + A R + VLW REAR+L+++ RTA+R R Sbjct 75 DQ--ATRFVLEG----SPEDLGEVITGIATTAGERRYMGVLWNREARFLDDEARTAMRAR 128 Query 131 INAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMA 190 + + PDLS ++L WA + LTS HS L +++ +L + +A Sbjct 129 FFTFIDEFSRQLRSARPDLSAGQADLLTWAALAVLTSPSYHSTELEPDDIIDMLERMALA 188 Query 191 AARTPPV-----CELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIG 245 T E PP+P R R E +LAA L GY AV+ ++G Sbjct 189 VCTTSLTGSDDGAEPPPVPTVVGLRPHG-----RREAILAAATPLIHQFGYQAVSMEDVG 243 Query 246 KGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRI 305 + GI+G +Y+ F+ K +L A+I R E L RAL + +A+ + L+ ++ Sbjct 244 ESVGISGAAVYKYFAKKSDLLSAVIARASEPLQLGASRALGRARDSAEGITNLLDAYIEF 303 Query 306 SLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAA 365 +L DLV + V E+++ E R R+Q D A WI L+ + P + R LV A Sbjct 304 ALVHHDLVGILVAEVTNLPEEHRRQVRRSQHDYVAEWIRLVRETRPDIDERRARFLVHAV 363 Query 366 ISFIEDVARTWHLTRYAGVADEISGLALAIL 396 ++ + DV RT HL R V ++ + IL Sbjct 364 LTVVNDVTRTDHLRRRPSVEQDLQIMCRRIL 394 >gi|111020231|ref|YP_703203.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|110819761|gb|ABG95045.1| possible transcriptional regulator [Rhodococcus jostii RHA1] Length=416 Score = 187 bits (475), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 147/389 (38%), Positives = 199/389 (52%), Gaps = 21/389 (5%) Query 18 QILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQY---- 73 QIL A LF + GFH+V++EDIAEA VTARA+YRH+ NKQ LL++ + QD+ Sbjct 23 QILHNASELFTKYGFHAVRMEDIAEATDVTARAIYRHFANKQDLLSQVVLEDQDRLLMAA 82 Query 74 QSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINA 133 QSA R G L L ++ A++ S L LWQREAR+L DD VR Sbjct 83 QSAERSETGVCS-----LEELLTRMVEASLESLRLGPLWQREARHLTADDFERVREGTRR 137 Query 134 IVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAAR 193 I +R ++ P S +++RAW S +TS G L L LL A +AA Sbjct 138 IGGAVRRAIEKADPSKSRFGADVRAWMAVSIITSPGHCDRLLSQRRLSPLLVSAALAAIN 197 Query 194 TPPVCELPP----LPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAG 249 TP P PA +A SR E ++AA AR FR +G+ V+ E G Sbjct 198 TPEFASASPESRDAPAAEAPVANERPGTSRREQIIAAAARAFRERGFGGVSLDEFG---- 253 Query 250 IAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDA 309 IAGP +YR F SK IL A+I R+ EW LE R + + Q + GLV+G+VRI+ +A Sbjct 254 IAGPAVYRYFDSKADILSAMIIRVQEWMALESSRTMHHSVSDEQVIEGLVRGYVRIATEA 313 Query 310 PDLVAVSVTELSH--ASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAIS 367 DL AVSVTE + AS RD +R D A W+ + + A LV A + Sbjct 314 TDLFAVSVTEALNLPASAAERDRRIRQ--DDLAEWVKWLRTSRSEVTEADALALVNAVRT 371 Query 368 FIEDVARTWHLTRYAGVADEISGLALAIL 396 + D+ R HL+R+A DE+ ++ L Sbjct 372 ALNDLVRIPHLSRHAEFPDELVACSMNAL 400 >gi|226308415|ref|YP_002768375.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226187532|dbj|BAH35636.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=405 Score = 182 bits (461), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 130/408 (32%), Positives = 199/408 (49%), Gaps = 43/408 (10%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 V RRP DRK+QIL A LF E G+H+V + +A G+TA ALYRH+ NK LL A+ Sbjct 25 VVRRPHDRKQQILAAAGELFREHGYHNVSVAQVAAGVGITAPALYRHFKNKPDLLYAAVN 84 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVAS----RALTVLWQREARYLNEDD 123 G + R+ E DL+ +IA S R L++LWQREARYL ++ Sbjct 85 AGIESLYD--RVAGSE----------DLKSMIAELAVSVSRRRGLSLLWQREARYLPDEQ 132 Query 124 RTAVRRRINAIVAGMRDSVLL--EVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELK 181 R +R + + A RD+ L+ E P+L + S L AWA+ + S+ H +SLP +++ Sbjct 133 REEMRATLKS--AAARDAALIRTERPELDEEDSYLLAWALIAVFNSVSSHRVSLPRRQME 190 Query 182 KLLYQACMAAART----------PPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLF 231 LL + A T P +P + R E LL RLF Sbjct 191 LLLAELAERAVHTELGHSEVKVETPTGHVP-------------LAMPRRELLLTEAIRLF 237 Query 232 RAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQA 291 +GY AVNT +IG+ AG GP +Y F +K +L A + R E R + +AL A Sbjct 238 DERGYQAVNTEDIGEAAGTTGPNVYNHFDAKIDLLIAAVSRGGERRRIGVAQALAAASGP 297 Query 292 AQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVP 351 L GL+ H+ +++ L+ + ++EL + R +NQ + A+W+ ++ + P Sbjct 298 EDALSGLLAAHIDFAINERHLIGLLISELDQLPDKFRRTCEQNQREYVALWVKMLDDVRP 357 Query 352 ATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSG 399 A R+ V AA++ +E+ R L R + + + + A+L G Sbjct 358 GLEPATARITVNAALTVVENAVRIGRLRRRDDLPERLFEIGSAVLLGG 405 Score = 52.8 bits (125), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 38/75 (51%), Gaps = 0/75 (0%) Query 196 PVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGL 255 PVC P+ A + R R + +LAA LFR GY V+ +++ G GI P L Sbjct 9 PVCSEIPVVAKERVRMVVRRPHDRKQQILAAAGELFREHGYHNVSVAQVAAGVGITAPAL 68 Query 256 YRSFSSKQAILDALI 270 YR F +K +L A + Sbjct 69 YRHFKNKPDLLYAAV 83 >gi|257056996|ref|YP_003134828.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] gi|256586868|gb|ACU98001.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] Length=400 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 129/400 (33%), Positives = 201/400 (51%), Gaps = 22/400 (5%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTG 69 +RP+DRK Q+ A LF +RG+H V + DIA AAGVT A+YRH+ +KQA+LA + +G Sbjct 6 KRPRDRKSQLAAVASELFRQRGYHGVGINDIAAAAGVTGPAIYRHFADKQAILAHVLLSG 65 Query 70 QDQYQSARRLTEGETEP----TPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRT 125 + A TE +P TP + L L A +V R LW+ E R+L+ + + Sbjct 66 LRDMEIA---TEAALDPERSSTPERIRELLSGLAARSVERRDTAALWRWEGRHLDAESQQ 122 Query 126 AVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLY 185 +RRR A+++ + + P+LS + +EL WA S S+ H ++L +LL Sbjct 123 QIRRRSTAMLSAWATVLRRKRPELSEEDAELLCWATLSVFGSVSVHRVTLAKRRFIELLT 182 Query 186 QACMAAART----PPVCE---LPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPA 238 + + P E +P +PA + SR E +L A LFR G+ A Sbjct 183 ELALRVLHVDLPEPDDAEPTAVPTVPAVTLGQP------SRRERVLTEAAELFRRHGFAA 236 Query 239 VNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQR--LR 296 V+ +IGK AGIAGP +YR F SK ++L A+ RR + + ALR + + +R LR Sbjct 237 VSMEDIGKAAGIAGPSVYRHFPSKASLLTAIGRRAGDRVMVAADHALRVSAPSDEREALR 296 Query 297 GLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVA 356 L +VR+ P+L+ + H + R R Q D W+ L+ + P Sbjct 297 RLADSYVRVLTGPPELLVFFSVDHVHIDEKDRSELSRIQRDYVTQWVRLLEAVHPGLDTR 356 Query 357 QGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 + +++V AA++ D+ART + A E++ L A+L Sbjct 357 EAKIIVHAALTIANDLARTRRVASRPHFATELTTLLHAVL 396 >gi|229491761|ref|ZP_04385582.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] gi|229321442|gb|EEN87242.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] Length=400 Score = 176 bits (445), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 120/389 (31%), Positives = 195/389 (51%), Gaps = 12/389 (3%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTG 69 RRP+DRK+QIL A LF E G+H++ + D+ +T ALYRHY NK +LL A+ G Sbjct 5 RRPRDRKQQILTAASELFREHGYHNISVSDVTARVDITTSALYRHYRNKNSLLYHAVLAG 64 Query 70 QDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRR 129 + E+ L L L A +V R L +LWQREARYL++D R +R+ Sbjct 65 IESLN--------ESVGGATDLYTLLTTLSATSVERRGLPLLWQREARYLDDDQREMLRK 116 Query 130 RINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACM 189 + + + + V DLS S L A+++ + +S H +S+P +++ LL+ Sbjct 117 ELRFSTSRISELVQAHRSDLSDSDSRLLAYSILAVFSSSSSHRISMPPRQMEALLFDLSA 176 Query 190 AAARTPPVCELPPLPAGDAARDEA-DVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGA 248 + +P P +PA AR E + SR E LL A +LF +GY V+ +IG Sbjct 177 RVSLSPIGSADPDVPA---ARTEVISIPVSRREQLLTAAIQLFDERGYRTVSNEDIGAAC 233 Query 249 GIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLD 308 G G +Y F +K IL I R + R L +AL ++Q L L+ H+ +L+ Sbjct 234 GTTGQNVYNHFDTKLDILSTAITRGFDRRDLAVRQALSQVGDSSQTLDILLGVHIAFALE 293 Query 309 APDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISF 368 L+ + TEL+ R ++ Q D +W+ + ++ P + + V+AA++ Sbjct 294 DGHLIGLMATELAELPDNTRKACVQAQRDYLELWVRALSEVRPGLDATEAKFTVSAAMTL 353 Query 369 IEDVARTWHLTRYAGVADEISGLALAILT 397 I + R + R A +AD ++ + +A++T Sbjct 354 IGNAIRIGSVRRRADLADRLTEICIALMT 382 >gi|229488384|ref|ZP_04382250.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] gi|229323888|gb|EEN89643.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] Length=382 Score = 176 bits (445), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 133/405 (33%), Positives = 199/405 (50%), Gaps = 43/405 (10%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 V RRP DRK+QIL A LF E G+H+V + +A A G+TA ALYRH+ NK LL A+ Sbjct 2 VVRRPHDRKQQILAAAGELFREHGYHNVSVAQVAAAVGITAPALYRHFKNKPDLLYAAVN 61 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVAS----RALTVLWQREARYLNEDD 123 G + R+ E DL+ LIA AS R L++LWQREARYL + Sbjct 62 AGIESLYD--RVAGSE----------DLKSLIAELAASVSRRRGLSLLWQREARYLPDGQ 109 Query 124 RTAVRRRINAIVAGMRDSVLL--EVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELK 181 R +R + + A RD+ L+ E P+L + S L AWA+ + S+ H +SLP +++ Sbjct 110 REEMRATLKS--AAARDAALIRTERPELDEEDSYLLAWALIAVFNSVSSHRVSLPRRQME 167 Query 182 KLLYQACMAAART----------PPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLF 231 LL + A T P +P V R E LL RLF Sbjct 168 LLLAELAERAVHTELGHSEGKMETPTGHVP-------------VAMPRRELLLTEAIRLF 214 Query 232 RAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQA 291 +GY AVNT +IG+ AG GP +Y F +K +L A + R E R + +AL A Sbjct 215 DERGYQAVNTEDIGEAAGTTGPNVYNHFDAKIDLLIAAVSRGGERRRIGVAQALAAATGP 274 Query 292 AQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVP 351 L GL+ H+ +++ L+ + ++EL + R +NQ + A+W+ ++ + P Sbjct 275 EDALSGLLAAHIDFAINERHLIGLLISELDQLPDKFRRTCEQNQREYVALWVKMLDDVRP 334 Query 352 ATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 A R+ V AA++ +E+ R L R + + + + A+L Sbjct 335 GLEPATARITVNAALTVVENAVRIGRLRRRDDLPERLFEIGSAVL 379 >gi|134099935|ref|YP_001105596.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291008670|ref|ZP_06566643.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133912558|emb|CAM02671.1| transcriptional regulator, TetR family [Saccharopolyspora erythraea NRRL 2338] Length=404 Score = 174 bits (442), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 123/358 (35%), Positives = 174/358 (49%), Gaps = 6/358 (1%) Query 18 QILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSAR 77 QI+ A LF RG+ V + DIAEA GV ALYRH+ +KQ LL E + + R Sbjct 24 QIVAAASELFHARGYPRVGMSDIAEAVGVGPSALYRHFASKQRLLTEVV------LEELR 77 Query 78 RLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAG 137 E L+A + +L AA+ R L VLWQREAR+L +R ++ + A+ G Sbjct 78 PFGEILGRVGTDDLDALVAELATAALDHRRLGVLWQREARHLPAAEREKLKGELRAVAGG 137 Query 138 MRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPV 197 + D + P L+ + + R W + S LTS H + LP E + LL P+ Sbjct 138 LADLARVRRPGLAEEDARFRGWCLFSALTSPSYHQVELPRAEFEGLLRNMVAVVTDQQPM 197 Query 198 CELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYR 257 A A SR LL+A RLF G+ AV T +IG AGIAGP +Y Sbjct 198 ALASRRTAEPATSPLLARRASRRAVLLSAATRLFADNGFTAVTTDDIGAAAGIAGPSVYS 257 Query 258 SFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSV 317 F+SKQ +L A+I R W +E R L A A + LR L+ ++ + D + + V Sbjct 258 HFASKQELLGAVIARGCAWLEIELERTLTATGDAEEALRELLHSYITFAYDHGRFIDILV 317 Query 318 TELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVART 375 TE+ H R + Q D A W+ L+ ++ P R+LV AA++ D+ART Sbjct 318 TEVGHLPDAERHRARQTQHDYVAEWVALLCRVRPDLDRVPARVLVQAALTAANDMART 375 Score = 45.1 bits (105), Expect = 0.022, Method: Compositional matrix adjust. Identities = 23/63 (37%), Positives = 34/63 (54%), Gaps = 0/63 (0%) Query 7 PVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAI 66 P+ R R+ +L A LF + GF +V +DI AAG+ ++Y H+ +KQ LL I Sbjct 211 PLLARRASRRAVLLSAATRLFADNGFTAVTTDDIGAAAGIAGPSVYSHFASKQELLGAVI 270 Query 67 RTG 69 G Sbjct 271 ARG 273 >gi|312137891|ref|YP_004005227.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|311887230|emb|CBH46539.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] Length=403 Score = 168 bits (426), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 132/399 (34%), Positives = 193/399 (49%), Gaps = 21/399 (5%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 +RRRPK+RK QI A F ERG+H V +++IA A G++ ALYRH+ NK AL ++A Sbjct 9 IRRRPKNRKAQIAAVAAEAFTERGYHGVSIDEIAAAVGISGPALYRHFPNKYALFSQAAT 68 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAA---AVASRALTVLWQREARYLNEDDR 124 ++A + + + + P++ ++AA VA R L++ E+RYL DR Sbjct 69 DLAKALENA--VAQDDADVVGDPVDRLDHQILAAVRTTVAHRRTAGLYRWESRYLEPPDR 126 Query 125 TAVR-------RRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG 177 AVR RRI A + +R PD++ + S A+ + S+ H +LP Sbjct 127 AAVRGAVEAVNRRIGATLEDIR-------PDITHRDSVQICVAILGAIGSITVHRAALPA 179 Query 178 EELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYP 237 L++LL AC + AR E P G R+ L ++ E +L LF A+GY Sbjct 180 RRLERLLLGACRSIARAELPAETPS--TGFHPRNAGIPLANKREVVLNEAILLFEARGYH 237 Query 238 AVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRG 297 V+ +IG+ AGI G+YR FSSK +L A R E + AL + Q L Sbjct 238 EVSIEDIGQAAGINASGVYRYFSSKSDLLAATFHRAAERLAVAVSTALGNSDTPRQALES 297 Query 298 LVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQ 357 LV+ +VR+S +L++V E+ R Q W L+G+ P SVA+ Sbjct 298 LVEVYVRLSFAQSELMSVYFAEIGSLPAPERTSLRNTQRLNVEEWALLLGEARPDLSVAE 357 Query 358 GRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 R LV AA+S + DV R H A + L LA L Sbjct 358 CRFLVHAALSLVLDVGRVMHFESTAANEARVRQLMLATL 396 >gi|111019999|ref|YP_702971.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|110819529|gb|ABG94813.1| probable transcriptional regulator [Rhodococcus jostii RHA1] Length=398 Score = 168 bits (426), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 130/390 (34%), Positives = 194/390 (50%), Gaps = 19/390 (4%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTG 69 RRP++RK QI+ A F RG+H V +EDIA A G+TA ALYRH+ NKQ LLA+AI Sbjct 20 RRPRNRKAQIITVAREQFGRRGYHGVNMEDIASAVGITAGALYRHFPNKQDLLAQAI--- 76 Query 70 QDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRR 129 +A LT + P ++ + + + VL+ +E+R L D R V+ Sbjct 77 ---LDAASSLTATLDDIDPEDSASNFLAMFRYCLDNDFRAVLFDQESRNLVPDRRAEVQT 133 Query 130 RINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACM 189 + ++VA + D++ E PDL+ +++ AWA+SS S RH +LP + + LL + Sbjct 134 AVRSVVARIADALRAERPDLTAADADMLAWAMSSVALSPARHRTTLPRKRWESLLLE-LF 192 Query 190 AAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAG 249 R P+ +PA + A SR ETLL A LFR +GY +V +IG AG Sbjct 193 DRLRDAPILHTEEIPA-EEAHVSGFAHASRRETLLTAAISLFRQRGYQSVTMDDIGAAAG 251 Query 250 IAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDA 309 +A +Y F SK +L A++ R +E + +RAL Q L +V + ++ A Sbjct 252 MASSSIYTYFGSKVEVLQAILSRGNETLRMGLVRALAGAQSREDALTRVVHSYA-TAVAA 310 Query 310 PD-LVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQGRLLVAAAI 366 PD + + + E ++ E + G RE + W+ L+G T + R V AAI Sbjct 311 PDSAIGILIEESTNLPEEAQSQ--SRTGQREYIDEWVHLLG-----TDTHETRTTVLAAI 363 Query 367 SFIEDVARTWHLTRYAGVADEISGLALAIL 396 I + R HL DEI LAL +L Sbjct 364 DLINGLFRLRHLRARPQHQDEIEDLALRVL 393 >gi|325673342|ref|ZP_08153034.1| transcriptional regulator [Rhodococcus equi ATCC 33707] gi|325555932|gb|EGD25602.1| transcriptional regulator [Rhodococcus equi ATCC 33707] Length=420 Score = 168 bits (426), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 132/399 (34%), Positives = 192/399 (49%), Gaps = 21/399 (5%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 +RRRPK+RK QI A F ERG+H V +++IA A G++ ALYRH+ NK AL ++A Sbjct 26 IRRRPKNRKAQIAAVAAEAFTERGYHGVSIDEIAAAVGISGPALYRHFPNKYALFSQAAT 85 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAA---AVASRALTVLWQREARYLNEDDR 124 ++A + + + + P++ ++AA VA R L++ E+RYL DR Sbjct 86 DLAKALENA--VAQDDADVVGDPVDRLDHQILAAVRTTVAHRRTAGLYRWESRYLEPPDR 143 Query 125 TAVR-------RRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG 177 AVR RRI A + +R PD++ + S A+ + S+ H +LP Sbjct 144 AAVRGAVEAVNRRIGATLEDIR-------PDITHRDSVQICVAILGAIGSITVHRAALPA 196 Query 178 EELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYP 237 L++LL AC + AR E P G R+ L ++ E +L LF A GY Sbjct 197 RRLERLLLGACRSIARAELPAETPS--TGVHPRNAGIPLANKREVVLNEAILLFEAHGYH 254 Query 238 AVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRG 297 V+ +IG+ AGI G+YR FSSK +L A R E + AL + Q L Sbjct 255 EVSIEDIGQAAGINASGVYRYFSSKSDLLAAAFHRAAERLAVAVSTALGKSDTPRQALES 314 Query 298 LVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQ 357 LV+ +VR+S +L++V E+ R Q W L+G+ P SVA+ Sbjct 315 LVEVYVRLSFAQSELMSVYFAEIGSLPAPERTSLRNTQRLNVEEWALLLGEARPDLSVAE 374 Query 358 GRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 R LV AA+S + DV R H A + L LA L Sbjct 375 CRFLVHAALSLVLDVGRVMHFESTAANEARVRQLMLATL 413 >gi|226361784|ref|YP_002779562.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226240269|dbj|BAH50617.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=389 Score = 167 bits (424), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 134/401 (34%), Positives = 186/401 (47%), Gaps = 34/401 (8%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK+QIL+ A L +E G+ +V + IA+ G+TA ALYRH+ NK LL I Sbjct 14 VRRRPKDRKEQILEAARALIVEVGYRNVSMAMIADRVGITAGALYRHFANKSVLLGAVIE 73 Query 68 TGQDQ----YQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDD 123 D+ + S RL + E R AV+ + + LW REAR L ++ Sbjct 74 QSFDEVTPTFGSRARLADALAESCER------------AVSHQDVGALWWREARNLPDEK 121 Query 124 RTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKL 183 +R R+ I D V E P L + +E AW V S L S H+ +P E L Sbjct 122 LEELRERLRVINKQYADLVAAERPTLPEEQAEELAWGVQSILASPSSHTSRIPEPEFAAL 181 Query 184 LYQACMAAARTPPVCE--LP-PLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 L C +CE LP P PA + + + S+ E LL LF +GY A Sbjct 182 LTAVCAG------LCETRLPAPSPAVEQTVSRLEPV-SKREALLGHAIVLFGEKGYEATG 234 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDE--WRCLECIRALRANQQAAQRLRGL 298 EIG AG++GP LY F SK +L A + R W L + LR N L L Sbjct 235 LDEIGAAAGVSGPNLYSYFDSKADLLQAAVERGTSALWLLLHTV--LRENSAPKDALGAL 292 Query 299 VQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQG 358 V G+V ++ + L ++ E S S E R Q + A W L+ P A Sbjct 293 VSGYVELASNKTILTSLLQAEQSTLSDEAR----VRQREYVAEWTALLRACRPQLDQATA 348 Query 359 RLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSG 399 R+LV + + +AR HL A + +++ + LA+L SG Sbjct 349 RVLVHTGLGVVHTLARIEHLRANATLRADLAAMTLAVLFSG 389 >gi|333921631|ref|YP_004495212.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333483852|gb|AEF42412.1| Transcriptional regulator, TetR family [Amycolicicoccus subflavus DQS3-9A1] Length=396 Score = 166 bits (420), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 124/392 (32%), Positives = 190/392 (49%), Gaps = 13/392 (3%) Query 9 RRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRT 68 R+RP+DRKK IL A LFI RG+H V + DIA+A GVT ALYRHY NK+ LL + + T Sbjct 12 RKRPRDRKKTILSTATRLFIARGYHQVSMADIADAVGVTPTALYRHYRNKEELLEQTLLT 71 Query 69 GQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVR 128 +AR +++ P P L L A+++R + L +RE R+L+ + A+ Sbjct 72 ------AARGVSDTLVACDPAP-EVMLRTLAKVALSARGVHPLLRREVRHLHPAHQRAIA 124 Query 129 RRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQAC 188 + + V + +V P+L+ + AW ++ + S+ H +P E ++LL Q Sbjct 125 EAVVSSVRALSRTVRAMRPELAASQARFLAWCIAWVMGSISYHRADIPDAECEQLLAQIA 184 Query 189 MAAARTPPVCELPPL--PAGDAAR-DEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIG 245 PV PL GDA R EAD R E L+AA RLF QGY ++ Sbjct 185 RDVVNALPVTVPYPLLIAEGDAERLAEADASGVRSEELIAAATRLFAEQGYAGTTIEDVA 244 Query 246 KGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRI 305 AG+ GP +Y F K +L ++ R W RA+ + +R +++ + Sbjct 245 ARAGMVGPSIYHYFPRKSDLLKVVLDRCARWIDGYTSRAVSESGAPEDTVRSIMRYYAEF 304 Query 306 SLDAPDLVAVSVTELSHASVEVRDGYLRN-QGDREAVWIDLIGKLVPATSVAQGRLLVAA 364 S+ P L+AV+ TE H + E + R+ Q D W L+ + A+ RL V A Sbjct 305 SVAHPGLIAVAATEPMHLAREGKASRSRDIQRDGVTSWATLLQYSKTGMTRAEARLRVIA 364 Query 365 AISFIEDVARTWHLTRYAGVADEISGLALAIL 396 A + + + AG AD+++ + L IL Sbjct 365 ATTVVNNSVLRRPFG--AGRADDLTAVGLRIL 394 >gi|336178035|ref|YP_004583410.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata] gi|334859015|gb|AEH09489.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata] Length=396 Score = 166 bits (419), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 131/391 (34%), Positives = 191/391 (49%), Gaps = 12/391 (3%) Query 11 RPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQ 70 RP++R+ QI+ A LF G+H+V EDIA A G+TA ALYRH+ +K+ LL A+ Sbjct 15 RPRNRRAQIITAASELFYRFGYHNVGTEDIAGAVGITAGALYRHFRSKEELLVCALTDSF 74 Query 71 DQYQSA-RRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRR 129 D S R +G+ L A ++DL A R L VLW RE+R+LN++ R +R Sbjct 75 DLAASVVDRHHDGQ-------LTAMVQDLAETAGRRRDLGVLWSRESRHLNDEQRQRMRE 127 Query 130 RINAIVAGMRDSVLLEVPD-LSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQAC 188 R A +AG + L +V D LS +EL AW + LTS H + E + LL + Sbjct 128 RFFAFLAGFVVA-LNDVRDGLSRDDAELLAWCALAVLTSPSYHGVPAAPETMVALLRRMA 186 Query 189 MAAARTPPVCELPPLPAGDAARDEADVL-FSRYETLLAAGARLFRAQGYPAVNTSEIGKG 247 ++ T + + PA + EA + R E LL A ARLF +GY V E+G Sbjct 187 LSVC-TVDIAGVSGQPAPEPVTTEAGLSPQGRREALLVAAARLFSIRGYQTVTMEEVGAE 245 Query 248 AGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISL 307 G+ G+YR F++K +L A++ R E L RAL A L +V ++ ++ Sbjct 246 VGVTSAGVYRHFTTKADLLMAIVARAAESLQLGIARALAAATTPQAGLENVVAAYIDFAM 305 Query 308 DAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAIS 367 DLV V V E+ + R + Q D A W+ L+ P + A + Sbjct 306 AHTDLVNVLVAEVMNLPYWNRHRIRKAQHDYVAEWVSLMAATRPDLDRTAALFRIHAVLM 365 Query 368 FIEDVARTWHLTRYAGVADEISGLALAILTS 398 + DVART HL V +++ +A IL S Sbjct 366 VVNDVARTAHLRSQPKVTEKLRLVAAHILHS 396 >gi|326381889|ref|ZP_08203582.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] gi|326199315|gb|EGD56496.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] Length=380 Score = 156 bits (394), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 124/402 (31%), Positives = 186/402 (47%), Gaps = 34/402 (8%) Query 4 VAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLA 63 + +P+ RRPKDRK QILD A L + G+ +V + IA+ G+TA ALYRH+ NK LLA Sbjct 1 MTKPIARRPKDRKAQILDAARTLVVSDGYANVSMAQIADEVGITAGALYRHFANKAVLLA 60 Query 64 EAIRTGQDQYQSARRLTEGETEPTPRPLNAD---LEDLIAAA----VASRALTVLWQREA 116 I T D P++ D L D++ AA VA + VLW RE+ Sbjct 61 AVIGTSFDDVM---------------PVDQDDDRLRDVVEAACRSVVARPDVGVLWWRES 105 Query 117 RYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLP 176 R L +D R + R+ + + +E D+ + S AW V + L S G H+ LP Sbjct 106 RSLPDDLRAELAARLREVNQRYARLIRVERGDVDDRASRELAWGVQAILASPGFHATRLP 165 Query 177 GEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVL--FSRYETLLAAGARLFRAQ 234 + LL AC+ VC + P PA + R L S+ E +L LF Sbjct 166 PADYVDLLTSACLR------VCAVTPGPADASRRRRGGGLTPVSKREAMLGHAIELFARN 219 Query 235 GYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQR 294 GY A + S+IG AG++GP Y F+SK +++ + R L L N + + Sbjct 220 GYDATSLSDIGAAAGVSGPNTYSYFASKSELMEVCLDRGTTALWLTLHDVLAENDEPRRA 279 Query 295 LRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATS 354 L +V+ + R+++D L V T++ S VR Q + A W L+ P + Sbjct 280 LAAVVRSYARLAVDKTILTPVLGTDVVGHSDSVR----ARQREYVAEWTGLVVASRPELT 335 Query 355 VAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 RL V A+ I + R HL +++ +A+A+L Sbjct 336 EIGARLRVHTALGLINILTRIDHLAESGSFESDLAAMAIAVL 377 >gi|226365579|ref|YP_002783362.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226244069|dbj|BAH54417.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=410 Score = 154 bits (388), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 125/392 (32%), Positives = 184/392 (47%), Gaps = 27/392 (6%) Query 2 ASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQAL 61 A+ +P+RRRPK+RK QI + A F ERG+H+V +++IA G++ ALYRHY NK AL Sbjct 10 AATDRPIRRRPKNRKAQIANVAAEAFSERGYHAVGVDEIAATIGISGPALYRHYPNKYAL 69 Query 62 LAEAIRTGQDQYQSARRLTEG---ETEPTPRPLNADLEDLIAAAVA----SRALTVLWQR 114 L A T D Q+ G E EP R LE LIAA VA +R + L++ Sbjct 70 LVHAATTTADLLQATADGALGGVAELEPGDR-----LEHLIAALVANSIENRKVAGLYRW 124 Query 115 EARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAV-SSTLTSLGR--- 170 E RYL +D R+RI A+ + V + ++ P+ + + A + +STL+ LG Sbjct 125 EGRYLEAED----RKRIRAVFVHVTQCVAAPLREIRPELTAVDATTLGASTLSVLGSISA 180 Query 171 HSLSLPGEELKKLLYQAC--MAAARTPPVCELPPLPAGDAARDEADVL--FSRYETLLAA 226 H +L L LL AC + A PP P G A L S+ E L+ Sbjct 181 HRTTLATRRLDTLLKSACGSILNATLPPAV---PNAGGGAGTGPVRGLAVTSKRELLINE 237 Query 227 GARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALR 286 ++F GY + EIG AGI +YR F SK +L A+ R + + AL Sbjct 238 AVKIFDRHGYHDSSIEEIGAAAGINASSVYRHFPSKADLLAAVFYRASDRLAVATSAALA 297 Query 287 ANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLI 346 LR L + ++ +S P++++V E+ + R Q W+ L+ Sbjct 298 TATDPEDALRKLAESYLELSFGNPEVLSVYFAEIGNLPKNERTNLRNVQRLHVEEWVHLV 357 Query 347 GKLVPATSVAQGRLLVAAAISFIEDVARTWHL 378 + P S + R LV AA+ + D+ R H Sbjct 358 TAVRPELSAPEARFLVHAALGLVLDIGRLVHF 389 >gi|111023076|ref|YP_706048.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|110822606|gb|ABG97890.1| possible transcriptional regulator [Rhodococcus jostii RHA1] Length=412 Score = 153 bits (386), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 121/386 (32%), Positives = 183/386 (48%), Gaps = 15/386 (3%) Query 2 ASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQAL 61 A+ +P+RRRPK+RK QI + A F ERG+H+V +++IA G++ ALYRHY NK AL Sbjct 12 AATERPIRRRPKNRKAQIANVAAEAFSERGYHAVGVDEIAATIGISGPALYRHYPNKYAL 71 Query 62 LAEAIRTGQDQYQSARR-LTEG--ETEPTPRPLNADLEDLIAAAVASRALTVLWQREARY 118 L A T D Q+A EG E EP R L+ + L+A + +R + L++ E RY Sbjct 72 LVHAATTTADALQAAADGALEGMAEREPGDR-LDHLVSALVANTIENRKVAGLYRWEGRY 130 Query 119 LNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAV-SSTLTSLGR---HSLS 174 L +DRT RI + + V + +L P+ + + A + +STL+ +G H + Sbjct 131 LEAEDRT----RIRDVFVHVTQCVAGPLRELRPELTSVDATTLGASTLSVMGSISAHRTT 186 Query 175 LPGEELKKLLYQACMAAART--PPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFR 232 L L LL AC + R PP AG A V S+ E L+ ++F Sbjct 187 LATRRLDALLKSACESILRATLPPAVPADGRNAGTGAVRGLAVT-SKRELLINEAVKIFD 245 Query 233 AQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAA 292 GY + EIG AGI +YR F SK +L A+ R + + AL Sbjct 246 RHGYHDSSIEEIGAAAGINASSVYRHFPSKADLLAAVFYRASDRLAVATSAALSTATGPE 305 Query 293 QRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPA 352 LR L + ++ +S P++++V E+ + R Q W+ L+ + Sbjct 306 DALRKLAESYLELSFRNPEVLSVYFAEIGNLPKNERTNLRNVQRLHVEEWVHLVTTVRSE 365 Query 353 TSVAQGRLLVAAAISFIEDVARTWHL 378 S + R LV AA+ + D+ R H Sbjct 366 LSAPEARFLVHAALGLVLDIGRLVHF 391 >gi|300789712|ref|YP_003770003.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299799226|gb|ADJ49601.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340531376|gb|AEK46581.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=392 Score = 149 bits (375), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 124/371 (34%), Positives = 185/371 (50%), Gaps = 17/371 (4%) Query 11 RPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQ 70 RP+DRK Q+ A LF RGF V ++DIA+AAGVT ALYRH+ +KQA+LA + +G Sbjct 9 RPRDRKAQLAAVAAELFRARGFPGVSIKDIADAAGVTGPALYRHFADKQAILAYVVLSGF 68 Query 71 DQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRR 130 D + A ++ PT L + L L AV R + LW+ E R+L ++D+ + RR Sbjct 69 DDLEEATASALSDSVPTSDQLESLLSRLATQAVERREIAALWRWEGRHLPKEDQREIARR 128 Query 131 INAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACM- 189 +A ++L PDL + +EL WA S S+ H S+ +LL + + Sbjct 129 SALALAAWSKALLARRPDLPAEDAELLCWAALSVFGSVSVHHTSVARRRFAQLLVELALD 188 Query 190 ----AAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIG 245 V E P L G SR E +LA LF +G+ V+ +IG Sbjct 189 VLNATLPSPSSVPEPPSLRLGTP---------SRREQVLAEATALFAHRGFHDVSMEDIG 239 Query 246 KGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRI 305 AGIAGP +YR F SK A++ A+ R + L RAL+A + + L+ L +V Sbjct 240 AAAGIAGPSVYRHFPSKAALMVAIGHRAADRLALAAERALQAPDERSA-LQRLAASYVHT 298 Query 306 SLDAPD-LVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAA 364 L P+ LV+ S ++ + D LR Q D A W+ L+ + P+ + ++ V A Sbjct 299 ILHTPELLVSFSADRVTMPDRDKAD-LLRVQRDYVAQWVTLLSAVRPSLPAREAKITVHA 357 Query 365 AISFIEDVART 375 A++ D+ART Sbjct 358 ALTIANDLART 368 >gi|302529939|ref|ZP_07282281.1| predicted protein [Streptomyces sp. AA4] gi|302438834|gb|EFL10650.1| predicted protein [Streptomyces sp. AA4] Length=393 Score = 147 bits (372), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 130/390 (34%), Positives = 194/390 (50%), Gaps = 13/390 (3%) Query 11 RPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQ 70 RP+DRK Q+ A LF RGFH V + DIA AAGVT ALYRH+ +KQA+LA + G Sbjct 10 RPRDRKAQLAAVAAELFRARGFHGVGINDIAAAAGVTGPALYRHFADKQAILAYVVLAGI 69 Query 71 DQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRR 130 D +SA + ++ P P LNA L L AV R + LW+ E +L + R +RRR Sbjct 70 DDMESATAVALADSAPPPEQLNALLTGLATQAVERREIAALWRWEGPHLPREQRREIRRR 129 Query 131 INAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMA 190 A++ ++L P+L+ +EL WA S S+ H S+ + LL + M Sbjct 130 SGAVLDAWAKALLTLRPELAADEAELLCWAALSVFGSVAVHHTSVARKRFVPLLVELAMT 189 Query 191 AARTPPVCELPPLPAGDAARDEADVLF--SRYETLLAAGARLFRAQGYPAVNTSEIGKGA 248 V +L + A L SR E +L A LF +G+ AV+ +IG A Sbjct 190 ------VLDLSLPVPEEPAPPVTSSLGTPSRREQVLTAATGLFAERGFHAVSMEDIGAAA 243 Query 249 GIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLD 308 GIAGP +YR F SK A++ A+ R + L +AL+A + + L L +V I L Sbjct 244 GIAGPSVYRHFPSKAALMVAIGHRAADRLALAAEQALQAPDERSA-LSRLAASYVHILLR 302 Query 309 APDLVAVSVTELSHASVEVRD--GYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAI 366 P+L+ VS T ++ RD R Q D W+ L+ + P + ++ V AA+ Sbjct 303 TPELL-VSFTA-DRVTMPERDKADLRRVQRDYVDQWVSLLCAVFPELPAREAKIRVHAAL 360 Query 367 SFIEDVARTWHLTRYAGVADEISGLALAIL 396 + D++RT + + E++ + A+L Sbjct 361 TIANDLSRTGPIKSRPHLQTELTAVLHAVL 390 >gi|343924408|ref|ZP_08763957.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343765552|dbj|GAA10883.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=396 Score = 147 bits (371), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 122/378 (33%), Positives = 186/378 (50%), Gaps = 26/378 (6%) Query 6 QPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEA 65 + R + DRK+Q++D A LF++RG+ V + DIA +AGVTA ++YRH+D+KQ+LLA A Sbjct 12 KTTRTKGADRKRQLVDSAASLFVQRGYARVSVADIARSAGVTAPSVYRHFDDKQSLLAAA 71 Query 66 IRTGQDQYQSA--RRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDD 123 + G D ++ R L +G T + + A AV S LW+ + YL + Sbjct 72 VLAGVDDLEACTDRVLRDGNDAVTL------ISTVCALAVESPQTASLWRWTSNYLTVEQ 125 Query 124 RTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG----EE 179 V RI ++ ++L DL+ + + AWA+ S SL H + EE Sbjct 126 NKQVALRIREVIGQWAAAILTGRDDLTEREAVQLAWAILSVSGSLTVHHTRMSSARAQEE 185 Query 180 LKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAV 239 ++KL+ + + T P + P+ +G V SR + +L A A LF +GY V Sbjct 186 IEKLVRRLLTLSPATAPTLDTAPVISG--------VTRSRRDEILDAAAALFADRGYSDV 237 Query 240 NTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLV 299 EIG+ GIAGP +Y+ F SK AIL A+ R + A A A+ L LV Sbjct 238 GVDEIGRAVGIAGPSVYKHFPSKMAILVAIGYRSGARLDAGVMAAYGATDDPAKLLAALV 297 Query 300 QGHVRISLDAPDLVAVSVTELSHASVEVRDG---YLRNQGDREAVWIDLIGKLVPATSVA 356 +V + PDL SV+ + + + + G L Q A WIDL+ ++ P+ Sbjct 298 DSYVDVITSTPDL---SVSFNNSSVLAGQPGATDLLDIQRRYVARWIDLLVEVDPSLKRD 354 Query 357 QGRLLVAAAISFIEDVAR 374 QG + V AA+S + D R Sbjct 355 QGAVAVHAALSVVNDAVR 372 >gi|229494482|ref|ZP_04388245.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis SK121] gi|229318844|gb|EEN84702.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis SK121] Length=423 Score = 139 bits (349), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 115/391 (30%), Positives = 184/391 (48%), Gaps = 30/391 (7%) Query 4 VAQP----VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQ 59 V QP V+RRPKDRK QI A F ERG+ +V ++DIA A G++ ALYRH+ NK Sbjct 21 VRQPRSDSVKRRPKDRKAQIAAAAAIAFSERGYPAVSVDDIASAVGISGSALYRHFPNKY 80 Query 60 AL-------LAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLW 112 A+ L EA+ + D A T+ + L DL +I + +R ++ Sbjct 81 AMFRHAALELTEALASALDAVSVAPAATDAQR------LREDLIAVIRTTIRNRRTAGIY 134 Query 113 QREARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHS 172 + E+R+L+ DDR +VR + +A+ + + ++ + L A+ S + S+ H+ Sbjct 135 RWESRFLDADDRKSVRAQASAVNRRVARYLSRTERAMTARDETLVVAAMFSVIGSITVHN 194 Query 173 LSLPGEELKKLLYQACMA-----AARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAG 227 L LP ++K+L AC+A A T E LP V ++ E LL Sbjct 195 LLLPQRAMEKVLLDACLAIDQGEGAITASRLEQSSLPRT--------VTTNKRERLLQEA 246 Query 228 ARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRA 287 RLF ++GY V+ EI AG+ G+YR F SK +L A+ R + L + Sbjct 247 VRLFDSRGYHDVSIEEIAAAAGLNASGMYRYFPSKAELLGAVFYRAADRLDLATAAVFDS 306 Query 288 NQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIG 347 Q LR L +V +S +L++V +E+++ R Q W ++G Sbjct 307 ATSHEQVLRSLSAMYVELSFAQHELMSVYFSEMNNLLPSHRSDLKNRQKLYVVEWARVLG 366 Query 348 KLVPATSVAQGRLLVAAAISFIEDVARTWHL 378 ++ P S + + +V AA++ + DV R Sbjct 367 EIRPELSAVEAKFVVHAALNLVPDVGRMMKF 397 >gi|183980756|ref|YP_001849047.1| putative regulatory protein [Mycobacterium marinum M] gi|183174082|gb|ACC39192.1| conserved hypothetical regulatory protein [Mycobacterium marinum M] Length=447 Score = 139 bits (349), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 114/376 (31%), Positives = 181/376 (49%), Gaps = 15/376 (3%) Query 5 AQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAE 64 A +RRRPKDRK QI A F +G+H+V +E IA GV+A ALYRHY K L Sbjct 23 ADGIRRRPKDRKAQIARAAAESFSAQGYHAVSMETIAAKVGVSAPALYRHYAGKYELFRG 82 Query 65 AIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDR 124 A+ Q +L + + +P + L+ + LI + +R L++ ++RYL +D+ Sbjct 83 AVLALSQQLVDCTQLDDSD-DPA-QLLDGLIASLIEVTLDNRLSGGLYRWQSRYLRAEDQ 140 Query 125 TAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLL 184 AV + + ++ + + P L P + + V S + S+ H L +E++ LL Sbjct 141 AAVADVLKVVNRRIQKPLTVIRPSLRPAQRWMLSAGVLSVIGSIVDHPARLAADEIRALL 200 Query 185 YQACMAAARTPPVCELPPLPAGDAARDEADVLF----SRYETLLAAGARLFRAQGYPAVN 240 +A A VC P P A R + +F S YETLL A LF+ +GY + Sbjct 201 GEAASAI-----VCAELPEPGDVAVRKASWRIFAEDASVYETLLHASMVLFKDRGYAQTS 255 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 ++I +G+ G+YR FS K IL +RR + + + A + Q L L+ Sbjct 256 MAQIASASGVPVSGIYRYFSGKCEILATGLRRAADRVSGQLSPIVGALTEPRQALTLLID 315 Query 301 GHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQG 358 +V S P+L AV TE A++ D L + + W+ L+ + P+ S + Sbjct 316 AYVATSFANPELAAVYYTE--RANLTPADQMLLHNIQLSTIDSWVRLLTSVRPSLSATRA 373 Query 359 RLLVAAAISFIEDVAR 374 R LV AA++ + D+ R Sbjct 374 RFLVHAAMALVVDLGR 389 >gi|302866624|ref|YP_003835261.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] gi|302569483|gb|ADL45685.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] Length=402 Score = 137 bits (344), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 126/406 (32%), Positives = 183/406 (46%), Gaps = 38/406 (9%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR-- 67 RRPKDRK +I LF ERG+H V +++IA A G++ A+YRH+ NK A+L A R Sbjct 14 RRPKDRKARIALAGAELFCERGYHGVSVDEIAAAVGISGPAVYRHFPNKYAILVHATREV 73 Query 68 -------TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 TGQ +A L L+ L L AV+ R + L+Q E RYL Sbjct 74 VGALLAATGQPAASNADGL-----------LDELLRALAEVAVSRRRVAGLYQWEGRYLT 122 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEV-PDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEE 179 + R + +V G + L E+ P+L+ ++L A S S+ + + G + Sbjct 123 PEHRQEFAASMATLV-GRVAAPLRELRPELTTAQADLLVNAALSAFGSVTTYRAAATGTD 181 Query 180 LKKLLYQACMAAART-PPVCEL------PPLPAGDAARDEADVLFSRYETLLAAGARLFR 232 + LL + RT P L +PA R SR E LL RLF Sbjct 182 TEHLLTRVAWTLLRTDAPTVPLRRRTAPEDMPATGPVRPA-----SRRELLLIEAMRLFH 236 Query 233 AQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAA 292 GY AV +IG+ AG+ +YR F K +L A R + A+ A Sbjct 237 RHGYHAVAVEDIGRAAGMQASSVYRYFPGKADLLAAAYYRATDRLTGATTAAIAEASDPA 296 Query 293 QRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLV 350 L +V+ +V + DLVAV + E + ++ RD + R V W+ L+ + Sbjct 297 DALHRVVRAYVDFAFGQSDLVAVYLAE--NNNLPDRDRHQLRGAQRLHVEEWVGLVRAVR 354 Query 351 PATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 P A R+LV AA++ + DV R R AG D+ + LALA+L Sbjct 355 PDLPAADARVLVHAALNVVTDVGRLGRFDRTAGYDDQTARLALAVL 400 >gi|229494286|ref|ZP_04388049.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis SK121] gi|229318648|gb|EEN84506.1| transcriptional regulator, TetR family protein [Rhodococcus erythropolis SK121] Length=407 Score = 136 bits (343), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 112/378 (30%), Positives = 174/378 (47%), Gaps = 13/378 (3%) Query 9 RRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRT 68 R RPK+RK QI A F ERG+H+V +++IA G++ ALYRH+ K AL + Sbjct 17 RTRPKNRKAQIAAAAAEAFSERGYHAVGIDEIAAKVGISGPALYRHFPTKYALFVYTVNN 76 Query 69 -GQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAV 127 Q ++ G P + LN+ + +I A + +R L++ E RYL ++DR + Sbjct 77 LTQALLDASDPAVHGNENPREQ-LNSTMVGVIRATIENRRRGGLYRWEGRYLVDEDREQL 135 Query 128 RRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQA 187 R + + + + + P+L P EL A AV S + S+ H +L ++++ L+ A Sbjct 136 RVGMRTLNLRIAEPLAAVRPELDPADVELIAPAVLSVIASITGHRSALSAKQIEALILAA 195 Query 188 CMAAARTPPVCELPPLPAGDAARDEAD------VLFSRYETLLAAGARLFRAQGYPAVNT 241 C + ELP D AR EA V S+ E LL LF +GY V+ Sbjct 196 CWSVIG----VELPAAEE-DGARAEASERKTGLVRTSKREVLLQEAVLLFYQRGYHDVSI 250 Query 242 SEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQG 301 EIG AGI +YR F+SK +L A R + + AL ++ + L + Sbjct 251 EEIGAAAGINASSVYRHFASKADLLAAAFHRASDRLTMTLGSALAESETPLAAVETLAKM 310 Query 302 HVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLL 361 +V +S +L+AV E+ R Q W L + P ++ Q R L Sbjct 311 YVEVSFGTSELLAVYFAEIGSLPDRSRTELRNIQRLNVEEWAHLCVEARPELTIVQARFL 370 Query 362 VAAAISFIEDVARTWHLT 379 V AA+ + D+ R H + Sbjct 371 VHAALGLVFDIGRIVHFS 388 >gi|262204323|ref|YP_003275531.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262087670|gb|ACY23638.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=390 Score = 136 bits (343), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 124/381 (33%), Positives = 179/381 (47%), Gaps = 38/381 (9%) Query 9 RRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRT 68 R R D K+Q++ A LF+ RG+ V L DIA +AGVTA ++YRH+D+KQALL A+ Sbjct 9 RTRGADTKRQLVASAAELFLRRGYPQVSLADIARSAGVTAPSVYRHFDDKQALLEAAVLA 68 Query 69 GQDQYQ--SARRLTEGETEPTPRPLNADLEDLIAA----AVASRALTVLWQREARYLNED 122 G D+ + + R L +G AD ++LIA+ V LW+ + YL + Sbjct 69 GVDELEVCTERALADG----------ADTDELIASVCTLGVQRPQAASLWRWTSNYLTVE 118 Query 123 DRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG----E 178 V R ++ ++ DL+ + + AWA S SL H + E Sbjct 119 QNKQVALRTREVIGKWASALADGRDDLTDREAVQLAWASLSVCGSLTVHHSRMSAARARE 178 Query 179 ELKKLLYQACMAAARTPPVCELPP--LPAGDAARDEADVLFSRYETLLAAGARLFRAQGY 236 EL+K++ + V L P PA D A A V +R + +L A A LF A+GY Sbjct 179 ELEKMIRR----------VVALRPASAPALDVAAPVAAVTATRRDEILDAAAELFAARGY 228 Query 237 PAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLR 296 V EIG GIAGP +Y+ F SK AIL + +R W I + A A+ L Sbjct 229 TDVGIDEIGAAVGIAGPSVYKHFPSKLAILVGIGQRSAMWLEAGVIASFAATSDPAKLLA 288 Query 297 GLVQGHVRISLDAPDLVAVSVTELSHASVEVRDG---YLRNQGDREAVWIDLIGKLVPAT 353 L+ +V + DL SV S ++ + G L Q A WIDL+ ++ P Sbjct 289 LLIDSYVTVITSTTDL---SVAFNSSTAMRGQSGAAELLDIQRRYVARWIDLLIQVDPGL 345 Query 354 SVAQGRLLVAAAISFIEDVAR 374 QG + V AA+S + D R Sbjct 346 RRDQGAVAVHAALSIVNDAVR 366 >gi|315503032|ref|YP_004081919.1| regulatory protein TetR [Micromonospora sp. L5] gi|315409651|gb|ADU07768.1| regulatory protein TetR [Micromonospora sp. L5] Length=402 Score = 136 bits (342), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 126/406 (32%), Positives = 183/406 (46%), Gaps = 38/406 (9%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR-- 67 RRPKDRK +I LF ERG+H V +++IA A G++ A+YRH+ NK A+L A R Sbjct 14 RRPKDRKARIALAGAELFCERGYHGVSVDEIAAAVGISGPAVYRHFPNKYAILVHATREV 73 Query 68 -------TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLN 120 TGQ +A L L+ L L AV+ R + L+Q E RYL Sbjct 74 VGALLAATGQPAASNADGL-----------LDELLRALAEVAVSRRRVAGLYQWEGRYLT 122 Query 121 EDDRTAVRRRINAIVAGMRDSVLLEV-PDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEE 179 + R + +V G + L E+ P+L+ ++L A S S+ + + G + Sbjct 123 PEHRQEFAASMATLV-GRVAAPLRELRPELTTAQADLLVNAALSAFGSVTTYRAAATGAD 181 Query 180 LKKLLYQACMAAART-PPVCEL------PPLPAGDAARDEADVLFSRYETLLAAGARLFR 232 + LL + RT P L +PA R SR E LL RLF Sbjct 182 TEHLLTRVARTLLRTDAPTVPLRRRTAPQDMPATGPVRPA-----SRRELLLIEAMRLFH 236 Query 233 AQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAA 292 GY AV +IG+ AG+ +YR F K +L A R + A+ A Sbjct 237 RHGYHAVAVEDIGRAAGMQASSVYRYFPGKADLLAAAYYRATDRLTGATTAAIAEASDPA 296 Query 293 QRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLV 350 L +V+ +V + DLVAV + E + ++ RD + R V W+ L+ + Sbjct 297 DALHRVVRAYVDFAFGQSDLVAVYLAE--NNNLPDRDRHQLRGAQRLHVEEWVGLVRAVR 354 Query 351 PATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 P A R+LV AA++ + DV R R AG D+ + LALA+L Sbjct 355 PDLPAADARVLVHAALNVVTDVGRLGRFDRTAGYDDQTARLALAVL 400 >gi|343924104|ref|ZP_08763667.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343765909|dbj|GAA10593.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=424 Score = 135 bits (341), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 117/363 (33%), Positives = 172/363 (48%), Gaps = 21/363 (5%) Query 19 ILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARR 78 I+D A F + G+H+V+L+DIA+A G++A ALYRH+ NK AL AE +SA Sbjct 32 IIDAAAKAFSDGGYHAVRLDDIADAVGISAPALYRHFPNKYALFAETTAVLARSLRSALD 91 Query 79 LTE--GETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVA 136 E G+ E L L + AA+ +R L++ E+RYL DR VR + Sbjct 92 AVEPGGDDE-----LRELLVAITAASFENRRTGGLYRWESRYLAPADRDLVRDVVVHQHR 146 Query 137 GMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTP- 195 +R + PDL + L A++S S H SLP E+ L+ A Sbjct 147 RVRAAARRLRPDLRDADANLTVAAMTSVAASPTTHHSSLPAREVTTLISDAAFDLLDVDL 206 Query 196 PVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGL 255 P PP PA A + E +L LF A+G+ V +I AG+ G+ Sbjct 207 PDPVGPPAPAAHGLAPAA-----KREIILTEAINLFAARGFRDVTIEDIAHAAGLPASGV 261 Query 256 YRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAV 315 YR F SK AIL+A R + AL + L G+++ +VR++ + DL++V Sbjct 262 YRHFPSKVAILEAAFWRATDRVTAAIAEALADASTPHEALVGMMRRYVRLTCSSTDLISV 321 Query 316 SVTELSHASVEVRDGYLRNQG----DREAVWIDLIGKLVPATSVAQGRLLVAAAISFIED 371 TE+ HA+ E RD LR+Q D A W+ +P T R LV AA++ + D Sbjct 322 YETEIGHATPEARDA-LRHQQRITVDEWATWMSRERANLPIT---HARFLVHAALNVVTD 377 Query 372 VAR 374 ++R Sbjct 378 LSR 380 >gi|126433161|ref|YP_001068852.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126232961|gb|ABN96361.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=451 Score = 135 bits (341), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 119/386 (31%), Positives = 172/386 (45%), Gaps = 25/386 (6%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK QI + F G+H V ++ IA G++A ALYRHY K L +A+ Sbjct 43 VRRRPKDRKAQIARASAEAFSSLGYHGVSMDAIASRVGISAAALYRHYTGKYELFRDAVL 102 Query 68 TGQDQYQSARRLTEGE----------TEPTPRPLNADLEDLIAAAVASRALTVLWQREAR 117 Q A +GE TE R L + AA+A+R L++ EAR Sbjct 103 ALGQQLVDATAFVDGEISDDGFGAHITEDPERTLVHLATAVCDAALANRESGGLYRWEAR 162 Query 118 YLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG 177 +L DD+ + +I + + + + P+L + + A+ S L S+ H LP Sbjct 163 FLRGDDQATLDSQIRTVHRRFQQPLRMLRPELDSRQRWTLSTAMISVLGSIVDHRAKLPA 222 Query 178 EELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYP 237 +++ LL + +A P + A S+YE LL RLF +GY Sbjct 223 GQIRPLLAELVVALV---PAEFPDLPDDPEPPAPTAAAHRSKYEALLMESMRLFNLKGYR 279 Query 238 AVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRR-LDEWRC-LECIRALRANQQAAQRL 295 + +I G+ G+YR FS K IL RR D W + I A+++ A L Sbjct 280 DTSMEDIAAATGMPASGIYRYFSGKSDILAGAFRRSADRWSAEMSAILDTTADREEA--L 337 Query 296 RGLVQGHVRISLDAPDLVAVSVTE---LSHASVEVRDGYLRN-QGDREAVWIDLIGKLVP 351 L+ GHV S P+L V TE +S A ++ LRN Q W DL+ L P Sbjct 338 AKLIDGHVARSFSEPELDYVYYTERLNMSPADQQI----LRNLQRSTVETWADLVVTLRP 393 Query 352 ATSVAQGRLLVAAAISFIEDVARTWH 377 + Q R V AA++ D+ R H Sbjct 394 EWTAGQARFAVYAALAVTTDLGRLVH 419 >gi|333989495|ref|YP_004522109.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333485463|gb|AEF34855.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=404 Score = 135 bits (341), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 118/372 (32%), Positives = 181/372 (49%), Gaps = 13/372 (3%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALL-AEAI 66 VRRRPKDRK QI+ A F +RG+H+V +++IA G++ ALYRH+ NK ALL A A Sbjct 13 VRRRPKDRKVQIVRAAARAFSDRGYHAVGVDEIAAEVGISGPALYRHFTNKYALLVATAE 72 Query 67 RTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTA 126 T Q +A+R E + P R L A ++ LI A + R ++ E RYL DR Sbjct 73 YTAQALVTAAQRADEPDKPPQDR-LRAIIDALIEATIGMRREGAFYRWERRYLQPADRGR 131 Query 127 VRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQ 186 +R +A+ A + + + P L+ + A A S + S+ H L L+ LL + Sbjct 132 IRGSYDALNAALAEPLAALRPGLNAVDTVTLAAAALSVIGSISAHRTRLAAAPLQSLLAE 191 Query 187 ACMAAARTPPVCELPPLPAGDAARDEADVL--FSRYETLLAAGARLFRAQGYPAVNTSEI 244 C + + +LP P G R L S+ E LL R+F +G+ + EI Sbjct 192 LCWSVLTS---TDLPAAPDGPMPRRSERGLPSTSKRERLLTEAIRVFGQRGFYEASIEEI 248 Query 245 GKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVR 304 G AG+ G YR + SK A+L A ++R + L AL + + + + + Sbjct 249 GTAAGLQGSSAYRYYPSKAALLVAALQRASDRVLLAITDALAESSDPREAATRIAERYTA 308 Query 305 ISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQGRLLV 362 +S APDL+ + E A++ RD R+ V W L+G++ A + A R V Sbjct 309 LSFAAPDLINIYFAEF--ANLPERDQTHLRALQRQNVNEWAHLLGQVGSAETEAVFR--V 364 Query 363 AAAISFIEDVAR 374 AA++ + D+ R Sbjct 365 HAALALVVDIGR 376 >gi|118618877|ref|YP_907209.1| putative regulatory protein [Mycobacterium ulcerans Agy99] gi|118570987|gb|ABL05738.1| conserved hypothetical regulatory protein [Mycobacterium ulcerans Agy99] Length=447 Score = 135 bits (340), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 116/377 (31%), Positives = 178/377 (48%), Gaps = 17/377 (4%) Query 5 AQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAE 64 A +RRRPKDRK QI A F +G+H+V +E IA GV+A ALYRHY K L Sbjct 23 ADGIRRRPKDRKAQIARAAAESFSAQGYHAVSMETIAAKVGVSAPALYRHYAGKYELFRG 82 Query 65 AIRTGQDQYQSARRLTEGETEPTPRPLNADL-EDLIAAAVASRALTVLWQREARYLNEDD 123 A+ Q +L + + P L A L LI + +R L++ ++RYL +D Sbjct 83 AVLALSQQLVDCTQLDDSD---DPAQLLARLIASLIEVTLDNRLSGGLYRWQSRYLRAED 139 Query 124 RTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKL 183 + AV + + ++ + + L P + + V S + S+ H L +E++ L Sbjct 140 QAAVADVLKVVNRRIQKPLTVIRASLRPAQRWMLSAGVLSVIGSIVDHPARLAADEIRAL 199 Query 184 LYQACMAAARTPPVCELPPLPAGDAARDEADVLF----SRYETLLAAGARLFRAQGYPAV 239 L +A A VC P P A R + +F S YETLL A LF+ +GY Sbjct 200 LGEAASAI-----VCAELPEPGDVAVRKASWRIFAEDASVYETLLHASMVLFKDRGYAQT 254 Query 240 NTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLV 299 + ++I AG+ G+YR FS K IL +RR + + + A + Q L L+ Sbjct 255 SMAQIASAAGVPVSGIYRYFSGKCEILATGLRRAADRVSGQLSPIVGALTEPRQALTLLI 314 Query 300 QGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQ 357 +V S P+L AV TE A++ D L + + W+ L+ + P+ S + Sbjct 315 DAYVATSFANPELAAVYYTE--RANLTPADQMLLHNIQLSTIDSWVRLLTSVRPSLSATR 372 Query 358 GRLLVAAAISFIEDVAR 374 R LV AA++ + D+ R Sbjct 373 ARFLVHAAMALVVDLGR 389 >gi|86741171|ref|YP_481571.1| TetR family transcriptional regulator [Frankia sp. CcI3] gi|86568033|gb|ABD11842.1| transcriptional regulator, TetR family [Frankia sp. CcI3] Length=363 Score = 135 bits (339), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 108/366 (30%), Positives = 152/366 (42%), Gaps = 21/366 (5%) Query 37 LEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLE 96 + D+AEA V ALYRH+ KQ LL E I G + + +A L Sbjct 1 MTDLAEAVAVGPSALYRHFSGKQDLLREVIAAGLAPLRHLLDDLDLADRADHATASARLA 60 Query 97 DLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSEL 156 A + R + VLWQREAR+L DD +R + I + V P+L ++L Sbjct 61 ---ARCLDERHIGVLWQREARHLTPDDHALLRAEVREIGRRLTGRVRAARPELDAPTADL 117 Query 157 RAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADV- 215 WA+ + L S H L LP LL + TP LP AA Sbjct 118 LTWAMLAVLMSPSFHHLDLPRPAYDDLLAELTDLVLDTP-------LPGTCAASPPPPAG 170 Query 216 ----------LFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAI 265 L SR E LL R+F GY V ++G GI GP +Y F SK + Sbjct 171 PPPPAGPPLRLASRREALLTQAVRMFATHGYAGVGIEDVGNAVGITGPSVYHHFPSKLDM 230 Query 266 LDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASV 325 L +R ++ R + AA LR LV ++R + DL+ + +TE+ H Sbjct 231 LRTAFQRSTAALLMDVSAIYRTSNGAADALRRLVGSYIRFTQAHHDLIGLLITEVEHLPE 290 Query 326 EVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVA 385 + R R Q D W+ L+ + P R+ V AA++ + D ART HL GV Sbjct 291 DERHAARRAQHDYLTEWVHLLRLVHPELDPTAARIRVHAAVAVVNDTARTPHLRHNPGVP 350 Query 386 DEISGL 391 + + Sbjct 351 GAVESI 356 Score = 50.4 bits (119), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 45/176 (26%), Positives = 76/176 (44%), Gaps = 13/176 (7%) Query 11 RPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQ 70 R R++ +L QAV +F G+ V +ED+ A G+T ++Y H+ +K +L RT Sbjct 180 RLASRREALLTQAVRMFATHGYAGVGIEDVGNAVGITGPSVYHHFPSKLDML----RTAF 235 Query 71 DQYQSARRLTEGETEPTPRPLNADLEDLIAAAV----ASRALTVLWQREARYLNEDDRTA 126 + +A + T L L+ + + A L L E +L ED+R A Sbjct 236 QRSTAALLMDVSAIYRTSNGAADALRRLVGSYIRFTQAHHDLIGLLITEVEHLPEDERHA 295 Query 127 VRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLG-----RHSLSLPG 177 RR + + + L P+L P + +R A + + RH+ +PG Sbjct 296 ARRAQHDYLTEWVHLLRLVHPELDPTAARIRVHAAVAVVNDTARTPHLRHNPGVPG 351 >gi|226304140|ref|YP_002764098.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226183255|dbj|BAH31359.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=399 Score = 135 bits (339), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 115/389 (30%), Positives = 180/389 (47%), Gaps = 19/389 (4%) Query 1 MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQA 60 M+ R RPK+RK QI A F ERG+H+V +++IA G++ ALYRH+ K A Sbjct 1 MSGSGSAPRTRPKNRKAQIAAAAAEAFSERGYHAVGIDEIAAKVGISGPALYRHFPTKYA 60 Query 61 LLAEAIRT-GQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYL 119 L + Q ++ G +P + LN+ + +I A + +R L++ E RYL Sbjct 61 LFVYTVNNLTQALLDASDPAVHGNDDPREQ-LNSTMVGVIRATIENRRRGGLYRWEGRYL 119 Query 120 NEDDRTAVR---RRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLP 176 ++DR +R R +N +AG +V P+L P EL A AV S + S+ H +L Sbjct 120 VDEDREQLREGMRTLNLRIAGPLAAVR---PELDPADVELIAPAVLSVIASITGHRSALS 176 Query 177 GEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEAD------VLFSRYETLLAAGARL 230 ++++ L+ AC + EL P+ A D+ + A S+ E LL L Sbjct 177 AKQIESLILAACWSVIG----VEL-PVGAKDSGKKAAPERKPGLARTSKREVLLQEAVLL 231 Query 231 FRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQ 290 F +GY V+ EIG AGI +YR F+SK +L A R + + AL ++ Sbjct 232 FDQRGYHDVSIEEIGAAAGINASSVYRHFASKADLLAAAFYRASDRLTMTLGSALAESET 291 Query 291 AAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLV 350 + L + +V +S +L+AV E+ R Q W L + Sbjct 292 PLAAVETLAKMYVEVSFGRSELLAVYFAEIGSLPDRSRTELRNIQRLNVEEWAHLCVEAR 351 Query 351 PATSVAQGRLLVAAAISFIEDVARTWHLT 379 P ++ Q R LV AA+ + D+ R H + Sbjct 352 PELTIVQARFLVHAALGLVFDIGRIVHFS 380 >gi|119866625|ref|YP_936577.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|119692714|gb|ABL89787.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] Length=428 Score = 135 bits (339), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 119/386 (31%), Positives = 172/386 (45%), Gaps = 25/386 (6%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK QI + F G+H V ++ IA G++A ALYRHY K L +A+ Sbjct 20 VRRRPKDRKAQIARASAEAFSSLGYHGVSMDAIASRVGISAAALYRHYTGKYELFRDAVL 79 Query 68 TGQDQYQSARRLTEGE----------TEPTPRPLNADLEDLIAAAVASRALTVLWQREAR 117 Q A +GE TE R L + AA+A+R L++ EAR Sbjct 80 ALGQQLVDATAFVDGEISDDGFGAHITEDPERTLVHLATAVCDAALANRESGGLYRWEAR 139 Query 118 YLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG 177 +L DD+ + +I + + + + P+L + + A+ S L S+ H LP Sbjct 140 FLRGDDQATLDSQIRTVHRRFQQPLRMLRPELDSRQRWTLSTAMISVLGSIVDHRAKLPA 199 Query 178 EELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYP 237 +++ LL + +A P + A S+YE LL RLF +GY Sbjct 200 GQIRPLLAELVVALV---PAEFPDLPDDPEPPAPIAAAHRSKYEALLVESMRLFNLKGYR 256 Query 238 AVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRR-LDEWRC-LECIRALRANQQAAQRL 295 + +I G+ G+YR FS K IL RR D W + I A+++ A L Sbjct 257 DTSMEDIAAATGMPASGIYRYFSGKSDILAGAFRRSADRWSAEMSAILDTTADREEA--L 314 Query 296 RGLVQGHVRISLDAPDLVAVSVTE---LSHASVEVRDGYLRN-QGDREAVWIDLIGKLVP 351 L+ GHV S P+L V TE +S A ++ LRN Q W DL+ L P Sbjct 315 AKLIDGHVARSFSEPELDYVYYTERLNMSPADQQI----LRNLQRSTVETWADLVVTLRP 370 Query 352 ATSVAQGRLLVAAAISFIEDVARTWH 377 + Q R V AA++ D+ R H Sbjct 371 EWTAGQARFAVYAALAVTIDLGRLVH 396 >gi|108797539|ref|YP_637736.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|108767958|gb|ABG06680.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] Length=451 Score = 134 bits (338), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 119/386 (31%), Positives = 172/386 (45%), Gaps = 25/386 (6%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK QI + F G+H V ++ IA G++A ALYRHY K L +A+ Sbjct 43 VRRRPKDRKAQIARASAEAFSSLGYHGVSMDAIASRVGISAAALYRHYTGKYELFRDAVL 102 Query 68 TGQDQYQSARRLTEGE----------TEPTPRPLNADLEDLIAAAVASRALTVLWQREAR 117 Q A +GE TE R L + AA+A+R L++ EAR Sbjct 103 ALGQQLVDATAFVDGEISDDGFGAHITEDPERTLVHLATAVCDAALANRESGGLYRWEAR 162 Query 118 YLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPG 177 +L DD+ + +I + + + + P+L + + A+ S L S+ H LP Sbjct 163 FLRGDDQATLDSQIRTVHRRFQQPLRMLRPELDSRQRWTLSTAMISVLGSIVDHRAKLPA 222 Query 178 EELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYP 237 +++ LL + +A P + A S+YE LL RLF +GY Sbjct 223 GQIRPLLAELVVALV---PAEFPDLPDDPEPPAPIAAAHRSKYEALLVESMRLFNLKGYR 279 Query 238 AVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRR-LDEWRC-LECIRALRANQQAAQRL 295 + +I G+ G+YR FS K IL RR D W + I A+++ A L Sbjct 280 DTSMEDIAAATGMPASGIYRYFSGKSDILAGAFRRSADRWSAEMSAILDTTADREEA--L 337 Query 296 RGLVQGHVRISLDAPDLVAVSVTE---LSHASVEVRDGYLRN-QGDREAVWIDLIGKLVP 351 L+ GHV S P+L V TE +S A ++ LRN Q W DL+ L P Sbjct 338 AKLIDGHVARSFSEPELDYVYYTERLNMSPADQQI----LRNLQRSTVETWADLVVTLRP 393 Query 352 ATSVAQGRLLVAAAISFIEDVARTWH 377 + Q R V AA++ D+ R H Sbjct 394 EWTAGQARFAVYAALAVTIDLGRLVH 419 >gi|288919455|ref|ZP_06413787.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] gi|288349149|gb|EFC83394.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] Length=444 Score = 134 bits (337), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 126/435 (29%), Positives = 185/435 (43%), Gaps = 53/435 (12%) Query 10 RRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTG 69 RRP++RK QI A LF ERG+H V +++IA G++ A+YRH+ NK A+L A R Sbjct 13 RRPRNRKAQIALAAAELFCERGYHGVGIDEIAAVVGISGPAVYRHFPNKYAILLHASREL 72 Query 70 QDQYQSARRLTEGETEPTPRPLNADLEDLIAA----AVASRALTVLWQREARYLNEDDRT 125 D +A E P + L+AA +V R + L+Q +ARYL + Sbjct 73 IDTLVTA----ADEALAVPDEPAERMARLLAATARVSVQRRRVGALYQWQARYLEPAHQG 128 Query 126 AVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLY 185 VR + A+V + D +L PDL + L + A S + S+ H ++ +++L Sbjct 129 EVRAGLTALVRRITDLLLELRPDLPRPSAVLLSRAALSAIGSISTHRCAIADSRAEQILR 188 Query 186 QAC-------MAAARTPPVCELPPLPA--------------------------------- 205 A + A PV LPP P Sbjct 189 SAAWTLLTADLPADVAAPVL-LPPGPGQAGSESSGGDRVAGADAAGDDTADDTEVRHVTA 247 Query 206 -GDAARDEADVLF---SRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSS 261 G D SR E LL RLF GY AV+ +IG+ AGI G+YR F Sbjct 248 GGSGLPDGGSAPMRPGSRREALLTEAVRLFDRLGYHAVSIDDIGRAAGINASGVYRYFPG 307 Query 262 KQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELS 321 K +L A+ R E AL A LR L+ +V ++ DLV+V + E + Sbjct 308 KADLLAAVYYRAAERLSTSTTSALATASSPADALRRLIDAYVDLTFAHNDLVSVYLAENN 367 Query 322 HASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRY 381 + R R Q + W+ L+ + P + + RLL AA++ + D+ RT R Sbjct 368 NLPAPDRHELRRLQREHVEEWVRLLVTIRPELAANEARLLAHAALNLVMDLGRTTSFNRS 427 Query 382 AGVADEISGLALAIL 396 G + LAL +L Sbjct 428 NGSEQLVRFLALRML 442 >gi|118469469|ref|YP_885218.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118170756|gb|ABK71652.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=486 Score = 133 bits (334), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 119/380 (32%), Positives = 175/380 (47%), Gaps = 22/380 (5%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK QI + F G+H V +E IA G++A ALYRHY +K L +A+ Sbjct 81 VRRRPKDRKAQIARASAEAFSALGYHGVSMEAIASRVGISAAALYRHYSSKYELFRDAVL 140 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAA-----VASRALTVLWQREARYLNED 122 Q + P + L+AAA +A+R L++ EARYLNED Sbjct 141 NLGQQLVDCTAFADTADAPENSEDAREQLRLLAAALTDTSLANRESGGLYRWEARYLNED 200 Query 123 DRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSS-TLTSLGR---HSLSLPGE 178 D+ A +NA + + + + L P+ W +S+ TL+ +G H LP Sbjct 201 DQAA----LNAQMRTVHHRIQRPLQQLRPELISRERWMLSTATLSVIGSVVDHRGKLPAG 256 Query 179 ELKKLLYQ--ACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGY 236 +++++L + + AA P ELP L A A V ++YE LL RLF GY Sbjct 257 QIREVLGEIVESVLAADLP---ELPELGAAAAPATTPVVSAAKYEALLNESMRLFNKNGY 313 Query 237 PAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLR 296 +I G+ G+YR FS K IL A RR + + L A + L Sbjct 314 RDTTMEDIAAAVGMPASGIYRYFSGKADILAAGFRRAADRLSADMAEILAAGGEPEDVLA 373 Query 297 GLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATS 354 L+ +V S D P+L V TE ++ D + R AV W++++ + P S Sbjct 374 ALIDDYVTRSFDRPELEHVYYTE--RLNMTPADQKILRDLQRSAVESWVNVVMPVRPHWS 431 Query 355 VAQGRLLVAAAISFIEDVAR 374 Q R V AA++ + D+ R Sbjct 432 AGQARFAVHAAMALVIDLGR 451 >gi|54022691|ref|YP_116933.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] gi|54014199|dbj|BAD55569.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] Length=426 Score = 132 bits (332), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 103/322 (32%), Positives = 150/322 (47%), Gaps = 16/322 (4%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 VRRRPKDRK QI+ A F ERG++ V +++IA G++ ALYRH+ NK ALL A Sbjct 43 VRRRPKDRKAQIVRAAARAFSERGYYPVGVDEIAAEVGISGPALYRHFANKYALLVAAAE 102 Query 68 TGQDQ-YQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTA 126 G Q A+ + +P PR L+A ++ + + R L++ E RYL +DR Sbjct 103 EGARHLLQVAQAADDPALDPEPR-LDAVIKAISEHTIDIRREAGLYRWERRYLEREDRLR 161 Query 127 VRRRINAIVAGMRDSVLLEV----PDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKK 182 +RR I + D++ + P P + + AV S + S+ H +L G L Sbjct 162 IRR----IYDELNDTIAAPIARLRPGADPADLRMLSAAVMSAVASIAAHRTALSGARLLP 217 Query 183 LLYQACMAAARTPPVCELPPLPAG--DAARDEADVLFSRYETLLAAGARLFRAQGYPAVN 240 LL C A RT ELPP P D + S+ E LL R+F QGY + Sbjct 218 LLRDMCWAILRT----ELPPAPVDTEDEPAPRGLPVTSKREQLLTEAIRIFGRQGYHEAS 273 Query 241 TSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQ 300 EIG GI +YR FSSK +L A R + + AL +R + Sbjct 274 IEEIGAAVGINASSVYRYFSSKADLLAAAFHRTGDRVSVAITEALAEATSRPDAVRRIAA 333 Query 301 GHVRISLDAPDLVAVSVTELSH 322 +++ P+++ V E S+ Sbjct 334 RQAKLTFAMPEIMPVYYAEFSN 355 >gi|297189980|ref|ZP_06907378.1| TetR family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] gi|197718637|gb|EDY62545.1| TetR family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] Length=396 Score = 132 bits (332), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 115/384 (30%), Positives = 182/384 (48%), Gaps = 15/384 (3%) Query 16 KKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQS 75 K IL A+ F G+ + +++DIA A G+TA ALY H+ +KQ LL A+ D Sbjct 19 KALILAAAIDCFQRSGYQATEMKDIAAAVGITAAALYHHFRSKQELLGAALLDSSDHLWR 78 Query 76 ARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIV 135 E E L + L L + ++ R+ +++W RE R+L+ + R VR+R I Sbjct 79 TVAAAEAEG------LESLLRLLTSFSLDHRSYSIVWYREIRHLSSEHRDEVRQRQQRIS 132 Query 136 AGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQA--CMAAAR 193 + ++ PDL P + L +WAV + L S H + LP ++LL M R Sbjct 133 GTLGKALQSSRPDLGPTETALISWAVMAALGSPSYHRIELPRPRFEELLLGLGRAMTQVR 192 Query 194 TPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGP 253 P + P G R SR E LL A LF +GY AV+ ++G G++ Sbjct 193 LSP-TDAPAPRTGPRLRP-----VSRREALLTAAVTLFTERGYQAVSMEDVGAAVGVSRL 246 Query 254 GLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRIS-LDAPDL 312 +Y F SK +L A++ R+ E + R+L ++ + LR +V+ + + LD Sbjct 247 SVYNYFPSKADLLSAVLHRVSEEKWATLNRSLAQSETEEEALRRIVRSYAESTVLDRGSG 306 Query 313 VAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDV 372 + V+EL+H RD LR Q D A W+ L P S ++ +LV A + + + Sbjct 307 AMLLVSELAHIPSADRDALLRLQVDYVAEWVALFLGCRPTLSQSEAGILVNAVLVMLSVL 366 Query 373 ARTWHLTRYAGVADEISGLALAIL 396 R L++ +A ++ LAL IL Sbjct 367 PRLPLLSQRDDLAGPLAELALTIL 390 >gi|262203022|ref|YP_003274230.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262086369|gb|ACY22337.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=403 Score = 132 bits (331), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 116/362 (33%), Positives = 170/362 (47%), Gaps = 17/362 (4%) Query 19 ILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARR 78 ILD A F G+H+V+LEDIA+A G++A ALYRH+ K AL AE T + Sbjct 34 ILDAAAKAFSAGGYHTVRLEDIADAVGISAPALYRHFPTKYALFAE---TTARLADALAD 90 Query 79 LTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGM 138 P L+ L + ++ +R L++ E+RYL D VR I + Sbjct 91 AVGAVGCGHPGELDDLLTAITTTSIENRRTGGLYRWESRYLESSDGERVREVIINQHRRI 150 Query 139 RDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMA--AARTPP 196 R ++ P L ++L A++S + S H +LP E + L+ A ++ + P Sbjct 151 RSALRHRRPSLDDADADLITAAMTSVVASPSTHRAALPAREAEALIRAAALSLVSVELPA 210 Query 197 VCEL-PPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGL 255 +L PP P G V +R E +LA LF +G+ V +I + AGI G+ Sbjct 211 PAQLTPPTPVGL-------VPAARREVILAESIALFATRGFRDVTIDDIARAAGIPASGV 263 Query 256 YRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAV 315 YR F K AIL+A R + AL A + + LV +V +S + +L+ V Sbjct 264 YRHFEGKAAILEAAFWRASDRVTASIADALAAATTPHEAIVELVSRYVGLSCGSTELITV 323 Query 316 SVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQGRLLVAAAISFIEDVA 373 VTE+ H S + R LRNQ R V W + + P S Q R LV AA+ I D++ Sbjct 324 YVTEIGHVSPKQRTA-LRNQ-QRITVEEWATWVTRCRPELSATQARFLVHAALGAITDLS 381 Query 374 RT 375 RT Sbjct 382 RT 383 >gi|333920318|ref|YP_004493899.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333482539|gb|AEF41099.1| Transcriptional regulator, TetR family protein [Amycolicicoccus subflavus DQS3-9A1] Length=413 Score = 132 bits (331), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 121/397 (31%), Positives = 179/397 (46%), Gaps = 27/397 (6%) Query 13 KDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQAL-------LAEA 65 KDRK QI A +F +G++ V ++DIA GV+ ALYRH+ NK AL LA+ Sbjct 28 KDRKAQIARIAAEMFSTQGYNQVGIDDIAREVGVSGPALYRHFPNKYALFRHVALTLADV 87 Query 66 IRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRT 125 + S + + E + L A L LI + R L++ E RYLN DR Sbjct 88 LVEASTPQNSGLQSSNAEGD-----LQAVLLSLIRVTIEHRKTGGLYRWEDRYLNPADRR 142 Query 126 AVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLY 185 AVR RI + + V P LS + L + A S + S+ H L + +++++ Sbjct 143 AVRDRIKTVNRNVSIQVKRLRPGLSDREYTLLSGAALSVIGSITAHRTPLSEKRIQRVIL 202 Query 186 QACMAA----ARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNT 241 +A +A A P PP AG + S+ E LL A +LF +GY V+ Sbjct 203 EAAQSALWVDAHIVPQPPSPPRQAGLTPQ-------SKREQLLKAAIQLFFERGYHDVSI 255 Query 242 SEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQG 301 EIG A + G+YR F SK +L A R E + L + LR LV Sbjct 256 EEIGAAADLNASGVYRYFESKSDLLAAAFARASERLTADTTAVLAESTSPLDGLRRLVDL 315 Query 302 HVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQGR 359 +V +S DL++V TE+ E R N R V W L+ +++P + + R Sbjct 316 YVSLSSGQQDLMSVYFTEVGSLPAEQRREL--NTAQRLYVEEWATLLEQVLPGRQLIELR 373 Query 360 LLVAAAISFIEDVARTWHLTRYAGVADEISGLALAIL 396 LV A+++ D+ R + + GV +S L A L Sbjct 374 FLVHASLALALDIGRLVNFEKSPGVRAFLSRLMRAAL 410 >gi|120401734|ref|YP_951563.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954552|gb|ABM11557.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=408 Score = 130 bits (328), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 113/400 (29%), Positives = 179/400 (45%), Gaps = 19/400 (4%) Query 1 MASVA--QPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNK 58 MAS A +RRRPKDRK QI + F G++ V +E IA G++A ALYRHY +K Sbjct 1 MASTADDHGIRRRPKDRKAQIARASAEAFSALGYYGVSMEMIASRVGISAAALYRHYSSK 60 Query 59 QALLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARY 118 L +A+ Q EG+ L+ + L A+A+R L++ E RY Sbjct 61 YELFRDAVLNLGQQLVDGTAGIEGDDPQV--VLDRLVSALTDTALANRGSGGLYRWEGRY 118 Query 119 LNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGE 178 L DD+ + ++I+ + + + P+L+ + + A S + S+ H LP Sbjct 119 LRGDDQATLLQQIHTVHHRIHRPLSALRPELTARQRSTLSTAALSIVGSIVDHRAKLPAA 178 Query 179 ELKKLLYQ---ACMAAARTPPVCELPP--LPAGDAARDEADVLFSRYETLLAAGARLFRA 233 ++ L+ Q A + A + PP +PA A S+YE LL A +LF Sbjct 179 QVHALIAQISRAVLGAELSADPPRYPPDVVPARPTAEP------SKYEALLTASMQLFDR 232 Query 234 QGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQ 293 GY +I G+ G+Y+ FS K IL + RR + E + + Sbjct 233 NGYRDTTMEDIASAVGMPTSGIYKYFSGKSDILATIFRRAADRVSAELASVVATMSDPEE 292 Query 294 RLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVP 351 L ++ G+V+ S D P+L V +E + S D + R V W++L+ + P Sbjct 293 ALTAVIDGYVQRSFDQPELECVYYSERLNMSAA--DQRIVRDLQRSTVESWVELVVAVRP 350 Query 352 ATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGL 391 S A+ R V AA++ + D+ R + +SGL Sbjct 351 EWSAAEARFAVHAAMALVVDLGRLMRYENSEEARETVSGL 390 >gi|145220791|ref|YP_001131469.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145213277|gb|ABP42681.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=410 Score = 130 bits (327), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 113/392 (29%), Positives = 180/392 (46%), Gaps = 7/392 (1%) Query 8 VRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIR 67 +RRRPKDRK QI + F E G+H V +E IA G++A ALYRHY K L +A+ Sbjct 10 IRRRPKDRKAQIARASAEAFSELGYHGVSMEMIASRVGISAAALYRHYAGKYELFRDAVL 69 Query 68 TGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAV 127 Q +G+ L+ + LI A+A+R+ L++ E RYL DD+ + Sbjct 70 NLGQQLVDGTAGIDGDDPEV--VLDRLVSALIDIALANRSSGGLYRWERRYLRGDDQAEL 127 Query 128 RRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQA 187 +++ + ++ V + P+L+ + + AV S + S+ H LP ++ ++L Q Sbjct 128 LQQLRTVHHRLQTPVSILRPELTARQRSTLSTAVLSIVGSIVDHRAKLPAAQIHRVLTQV 187 Query 188 CMAAARTP-PVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGK 246 A T P P PA A R + S+YE LLA RLF GY + EI Sbjct 188 ARAILSTELPDAAPPATPAPAAERIRSAAESSKYEALLAESMRLFNLNGYRDTSMEEIAS 247 Query 247 GAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRIS 306 G+ G+Y+ FS K IL A+ RR + E + + L ++ +V + Sbjct 248 AVGMPASGIYKYFSGKNDILAAIFRRASDRVSAETAEIVSTVPDPQEALAAVIDAYVTRA 307 Query 307 LDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAV--WIDLIGKLVPATSVAQGRLLVAA 364 P++ ++ +E + S D + R V W++L+ + P + + R V A Sbjct 308 FGQPEMESLYYSERLNMSPS--DQRIVRDLQRSTVESWVELVAAVRPDWTPGEARFAVHA 365 Query 365 AISFIEDVARTWHLTRYAGVADEISGLALAIL 396 A++ + DV R H D + GL A L Sbjct 366 AMALVIDVGRLVHYAASDEARDTVEGLVDAAL 397 >gi|315442433|ref|YP_004075312.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315260736|gb|ADT97477.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=403 Score = 129 bits (325), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 113/380 (30%), Positives = 175/380 (47%), Gaps = 15/380 (3%) Query 9 RRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRT 68 RRRPKDRK+QI + F E G+H+V +EDIA GVTA +LYRHY K L A+ Sbjct 11 RRRPKDRKQQIARASAEAFSELGYHAVSMEDIASRVGVTAASLYRHYSGKYDLFRAAVLN 70 Query 69 GQDQYQSARRLTEGETEPTPRPL-NADLEDLIAAAVASRALTVLWQREARYLNEDDRTAV 127 +Q SA + E+ +P L + L AA+ +RA L++ EARYL E D+ Sbjct 71 LGEQLVSATAFADDESGDSPEELWERSVAALADAAIKTRASGGLYRWEARYLQEPDQAIS 130 Query 128 RRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQA 187 +I + ++ + P+L + +V S + S+ H LP ++++LL Sbjct 131 NEQIKVVNRRLQRPLSALRPELDSRQRWTVTASVLSAIGSICDHRAKLPVNDMRRLL--- 187 Query 188 CMAAARTPPVCELPPLPAGDA-ARDEADVL--FSRYETLLAAGARLFRAQGYPAVNTSEI 244 ++ AR +LPP+ A + R A + YE +LAA RLF G+ +I Sbjct 188 -VSLARRLRDADLPPVSAREKPGRRAAPSIGPAGEYEAILAAALRLFHDHGFRETGMDDI 246 Query 245 GKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRC--LECIRALRANQQAAQRLRGLVQGH 302 G+ +YR FS K A+L + RR + + I A+ +++ A + L+ + Sbjct 247 ASAIGLPASTIYRYFSGKSAVLSTIYRRAADRVSGDMGAILAMAPDERTA--VGQLIDAY 304 Query 303 VRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLV 362 V + P+L V E + E R Q W + P SV + R V Sbjct 305 VWRTFAEPELAYVYYAEQLNVPAEDRAALHNIQRSIVEGWARQVVAARPDLSVREARFAV 364 Query 363 AAAISFIEDVARTWHLTRYA 382 A + + D+ R L R+A Sbjct 365 HAGLGLVVDIGR---LERFA 381 Lambda K H 0.319 0.133 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 807118285248 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40