BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2063A
Length=136
Score E
Sequences producing significant alignments: (Bits) Value
gi|148661877|ref|YP_001283400.1| hypothetical protein MRA_2077 [... 257 4e-67
gi|289443566|ref|ZP_06433310.1| toxin [Mycobacterium tuberculosi... 253 5e-66
gi|308372136|ref|ZP_07667305.1| LOW QUALITY PROTEIN: toxin [Myco... 250 5e-65
gi|15841552|ref|NP_336589.1| hypothetical protein MT2123 [Mycoba... 203 9e-51
gi|289570173|ref|ZP_06450400.1| conserved hypothetical protein [... 199 1e-49
gi|339294987|gb|AEJ47098.1| toxin [Mycobacterium tuberculosis CC... 197 6e-49
gi|345462044|ref|YP_004837055.1| hypothetical protein Rv4013 [My... 165 2e-39
gi|312126605|ref|YP_003991479.1| transcriptional modulator of ma... 82.4 2e-14
gi|146297608|ref|YP_001181379.1| transcriptional modulator of Ma... 76.3 1e-12
gi|302872668|ref|YP_003841304.1| transcriptional modulator of Ma... 75.9 2e-12
gi|283851278|ref|ZP_06368560.1| transcriptional modulator of Maz... 73.6 9e-12
gi|333979032|ref|YP_004516977.1| transcriptional modulator of Ma... 72.8 2e-11
gi|289522518|ref|ZP_06439372.1| toxin-antitoxin system, toxin co... 72.0 3e-11
gi|312792908|ref|YP_004025831.1| transcriptional modulator of ma... 71.6 4e-11
gi|312128613|ref|YP_003993487.1| transcriptional modulator of ma... 70.9 6e-11
gi|344997339|ref|YP_004799682.1| transcriptional modulator of Ma... 70.1 1e-10
gi|148264028|ref|YP_001230734.1| transcriptional modulator of Ma... 67.4 6e-10
gi|166368979|ref|YP_001661252.1| PemK-like protein [Microcystis ... 66.2 1e-09
gi|312794276|ref|YP_004027199.1| transcriptional modulator of ma... 65.9 2e-09
gi|297660628|ref|YP_003710339.1| putative mazF-like toxin [Waddl... 64.3 6e-09
gi|256396397|ref|YP_003117961.1| transcriptional modulator of Ma... 63.9 8e-09
gi|153876884|ref|ZP_02003975.1| PemK-like protein [Beggiatoa sp.... 63.9 8e-09
gi|168699546|ref|ZP_02731823.1| PemK-like protein [Gemmata obscu... 63.5 9e-09
gi|297621433|ref|YP_003709570.1| putative mazF-like toxin [Waddl... 63.2 1e-08
gi|320161823|ref|YP_004175048.1| putative endoribonuclease [Anae... 62.8 2e-08
gi|307299621|ref|ZP_07579418.1| transcriptional modulator of Maz... 62.4 2e-08
gi|37520200|ref|NP_923577.1| hypothetical protein glr0631 [Gloeo... 61.2 4e-08
gi|269957099|ref|YP_003326888.1| transcriptional modulator of Ma... 60.8 7e-08
gi|268324783|emb|CBH38371.1| conserved hypothetical protein, Pem... 60.8 7e-08
gi|337293746|emb|CCB91733.1| mRNA interferase MazF [Waddlia chon... 59.3 2e-07
gi|328952780|ref|YP_004370114.1| transcriptional modulator of Ma... 58.5 3e-07
gi|120402156|ref|YP_951985.1| transcriptional modulator of MazE/... 58.5 3e-07
gi|334116633|ref|ZP_08490725.1| transcriptional modulator of Maz... 58.2 5e-07
gi|333992725|ref|YP_004525339.1| hypothetical protein JDM601_408... 57.8 5e-07
gi|134097900|ref|YP_001103561.1| hypothetical protein SACE_1313 ... 57.4 7e-07
gi|91203966|emb|CAJ71619.1| similar to YdcE protein, chain A [Ca... 56.2 2e-06
gi|186682027|ref|YP_001865223.1| MazF family transcripitonal reg... 56.2 2e-06
gi|311746303|ref|ZP_07720088.1| toxin-antitoxin system, toxin co... 55.8 2e-06
gi|339501431|ref|YP_004699466.1| transcriptional modulator of Ma... 55.5 3e-06
gi|164688914|ref|ZP_02212942.1| hypothetical protein CLOBAR_0256... 55.5 3e-06
gi|254431259|ref|ZP_05044962.1| PemK-like protein [Cyanobium sp.... 55.1 3e-06
gi|315636800|ref|ZP_07892026.1| PemK family transcriptional regu... 55.1 3e-06
gi|164515861|emb|CAP48095.1| putative integron gene cassette pro... 55.1 4e-06
gi|320326762|gb|EFW82805.1| plasmid maintenance protein [Pseudom... 54.3 5e-06
gi|166364143|ref|YP_001656416.1| PemK-like protein [Microcystis ... 54.3 6e-06
gi|224477058|ref|YP_002634664.1| hypothetical protein Sca_1574 [... 53.5 9e-06
gi|256848378|ref|ZP_05553821.1| regulatory protein [Lactobacillu... 53.5 9e-06
gi|340627801|ref|YP_004746253.1| hypothetical protein MCAN_28281... 53.1 1e-05
gi|15842339|ref|NP_337376.1| hypothetical protein MT2869 [Mycoba... 53.1 1e-05
gi|325282447|ref|YP_004254988.1| transcriptional modulator of Ma... 53.1 1e-05
>gi|148661877|ref|YP_001283400.1| hypothetical protein MRA_2077 [Mycobacterium tuberculosis H37Ra]
gi|167967796|ref|ZP_02550073.1| hypothetical protein MtubH3_07082 [Mycobacterium tuberculosis
H37Ra]
gi|253798880|ref|YP_003031881.1| toxin [Mycobacterium tuberculosis KZN 1435]
42 more sequence titles
Length=136
Score = 257 bits (657), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 135/136 (99%), Positives = 136/136 (100%), Gaps = 0/136 (0%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
+AEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR
Sbjct 1 MAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
Query 61 PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERG 120
PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERG
Sbjct 61 PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERG 120
Query 121 EAATHSPVRWTGGRDP 136
EAATHSPVRWTGGRDP
Sbjct 121 EAATHSPVRWTGGRDP 136
>gi|289443566|ref|ZP_06433310.1| toxin [Mycobacterium tuberculosis T46]
gi|289754173|ref|ZP_06513551.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
gi|289416485|gb|EFD13725.1| toxin [Mycobacterium tuberculosis T46]
gi|289694760|gb|EFD62189.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
Length=136
Score = 253 bits (647), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 134/136 (99%), Positives = 135/136 (99%), Gaps = 0/136 (0%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
+AEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR
Sbjct 1 MAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
Query 61 PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERG 120
PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATM AIENALTLILGLPTGPERG
Sbjct 61 PPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMPAIENALTLILGLPTGPERG 120
Query 121 EAATHSPVRWTGGRDP 136
EAATHSPVRWTGGRDP
Sbjct 121 EAATHSPVRWTGGRDP 136
>gi|308372136|ref|ZP_07667305.1| LOW QUALITY PROTEIN: toxin [Mycobacterium tuberculosis SUMu004]
gi|308334262|gb|EFP23113.1| LOW QUALITY PROTEIN: toxin [Mycobacterium tuberculosis SUMu004]
Length=132
Score = 250 bits (639), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 132/132 (100%), Positives = 132/132 (100%), Gaps = 0/132 (0%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA
Sbjct 1 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 60
Query 65 PSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERGEAAT 124
PSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERGEAAT
Sbjct 61 PSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERGEAAT 120
Query 125 HSPVRWTGGRDP 136
HSPVRWTGGRDP
Sbjct 121 HSPVRWTGGRDP 132
>gi|15841552|ref|NP_336589.1| hypothetical protein MT2123 [Mycobacterium tuberculosis CDC1551]
gi|254364877|ref|ZP_04980923.1| hypothetical protein TBHG_02021 [Mycobacterium tuberculosis str.
Haarlem]
gi|289554153|ref|ZP_06443363.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
6 more sequence titles
Length=108
Score = 203 bits (516), Expect = 9e-51, Method: Compositional matrix adjust.
Identities = 107/108 (99%), Positives = 108/108 (100%), Gaps = 0/108 (0%)
Query 29 VVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL 88
+VVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL
Sbjct 1 MVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL 60
Query 89 VERLGALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 136
VERLGALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP
Sbjct 61 VERLGALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 108
>gi|289570173|ref|ZP_06450400.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
gi|289750657|ref|ZP_06510035.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
gi|289543927|gb|EFD47575.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
gi|289691244|gb|EFD58673.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
Length=108
Score = 199 bits (507), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 106/108 (99%), Positives = 107/108 (99%), Gaps = 0/108 (0%)
Query 29 VVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL 88
+VVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL
Sbjct 1 MVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARL 60
Query 89 VERLGALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 136
VERLGALKPATM AIENALTLILGLPTGPERGEAATHSPVRWTGGRDP
Sbjct 61 VERLGALKPATMPAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 108
>gi|339294987|gb|AEJ47098.1| toxin [Mycobacterium tuberculosis CCDC5079]
gi|339298611|gb|AEJ50721.1| toxin [Mycobacterium tuberculosis CCDC5180]
Length=104
Score = 197 bits (500), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 103/104 (99%), Positives = 104/104 (100%), Gaps = 0/104 (0%)
Query 33 VDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERL 92
+DELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERL
Sbjct 1 MDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERL 60
Query 93 GALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 136
GALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP
Sbjct 61 GALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP 104
>gi|345462044|ref|YP_004837055.1| hypothetical protein Rv4013 [Mycobacterium tuberculosis H37Rv]
Length=87
Score = 165 bits (418), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 86/87 (99%), Positives = 87/87 (100%), Gaps = 0/87 (0%)
Query 50 VSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTL 109
+SSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTL
Sbjct 1 MSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTL 60
Query 110 ILGLPTGPERGEAATHSPVRWTGGRDP 136
ILGLPTGPERGEAATHSPVRWTGGRDP
Sbjct 61 ILGLPTGPERGEAATHSPVRWTGGRDP 87
>gi|312126605|ref|YP_003991479.1| transcriptional modulator of maze/toxin, mazf [Caldicellulosiruptor
hydrothermalis 108]
gi|311776624|gb|ADQ06110.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
hydrothermalis 108]
Length=112
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 44/111 (40%), Positives = 68/111 (62%), Gaps = 2/111 (1%)
Query 4 PRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPV 63
P+RG++WLV L R E RPAV++SVDE + D LVVVVP++S PL +
Sbjct 3 PQRGEIWLVDLNPTRGHEQSGIRPAVIISVDEFNSCPAD-LVVVVPITSKNKNIPLHVEI 61
Query 64 AP-SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P + G+A S A +R++++ RLV+++G L A M+ +E + ++LGL
Sbjct 62 QPENSGLAKISFAKPEDIRSISKERLVKKIGKLPEAKMKELEEKIKILLGL 112
>gi|146297608|ref|YP_001181379.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
saccharolyticus DSM 8903]
gi|145411184|gb|ABP68188.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
saccharolyticus DSM 8903]
Length=112
Score = 76.3 bits (186), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 41/110 (38%), Positives = 64/110 (59%), Gaps = 2/110 (1%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RG++WLV L R E RPAV++SVDE ELVVVVP++S PL +
Sbjct 4 KRGEIWLVDLSPTRGHEQSGIRPAVIISVDE-FNSCPAELVVVVPITSKNKNIPLHVEIQ 62
Query 65 P-SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P + G+ S A +R++++ RLV+++G L +R +E + ++LGL
Sbjct 63 PENSGLTRVSFAKPEDIRSISKERLVKKIGQLPNEKLRELEEKIKILLGL 112
>gi|302872668|ref|YP_003841304.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
obsidiansis OB47]
gi|302575527|gb|ADL43318.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
obsidiansis OB47]
Length=112
Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 41/110 (38%), Positives = 64/110 (59%), Gaps = 2/110 (1%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RG++WLV L R E RPAV+VSVDE + D LVVVVP++S PL +
Sbjct 4 KRGEIWLVDLNPTRGHEQSGVRPAVIVSVDEFNSCPAD-LVVVVPITSKNKNIPLHVKIQ 62
Query 65 PSEG-VAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P E + +S A +R++++ RLV+++G L ++ E + ++LGL
Sbjct 63 PKESRLDRESFAKPEDIRSISKERLVKKIGKLSDGKLKEFEEKIKVLLGL 112
>gi|283851278|ref|ZP_06368560.1| transcriptional modulator of MazE/toxin, MazF [Desulfovibrio
sp. FW1012B]
gi|283573228|gb|EFC21206.1| transcriptional modulator of MazE/toxin, MazF [Desulfovibrio
sp. FW1012B]
Length=106
Score = 73.6 bits (179), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 48/109 (45%), Positives = 65/109 (60%), Gaps = 4/109 (3%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
RRG++W V L R E K RPA +++VD L VVVVP+SS+ TP P V
Sbjct 2 RRGEVWWVDLDPTRGSEIRKKRPAAILTVDALNKA--RRTVVVVPLSSAA--TPRPPLVV 57
Query 65 PSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P E SVAVC +RAV ++RLVERLG L A ++ + ++ ++LGL
Sbjct 58 PMESAGKGSVAVCDQIRAVDKSRLVERLGELSLADLKILAASVAVVLGL 106
>gi|333979032|ref|YP_004516977.1| transcriptional modulator of MazE/toxin, MazF [Desulfotomaculum
kuznetsovii DSM 6115]
gi|333822513|gb|AEG15176.1| transcriptional modulator of MazE/toxin, MazF [Desulfotomaculum
kuznetsovii DSM 6115]
Length=113
Score = 72.8 bits (177), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 45/114 (40%), Positives = 64/114 (57%), Gaps = 2/114 (1%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
+A P RG++WLV L R E RPA+VVSVD +G ELVVV+P+++ PL
Sbjct 1 MATPLRGEVWLVDLNPVRGHEQAGRRPALVVSVDMFNSG-PAELVVVLPITTKDKGIPLH 59
Query 61 PPVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ P E GV S C +R+V+ RL RLG + M +E+ + ++LGL
Sbjct 60 VRIDPPEGGVKETSFVKCEDIRSVSTERLTARLGRVSRDVMALVEDRIRILLGL 113
>gi|289522518|ref|ZP_06439372.1| toxin-antitoxin system, toxin component, MazF family [Anaerobaculum
hydrogeniformans ATCC BAA-1850]
gi|289504354|gb|EFD25518.1| toxin-antitoxin system, toxin component, MazF family [Anaerobaculum
hydrogeniformans ATCC BAA-1850]
Length=113
Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 46/114 (41%), Positives = 64/114 (57%), Gaps = 2/114 (1%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
+AEP RG++WLV L E RPA+VVSVD G LV+V+P+++ PL
Sbjct 1 MAEPSRGEIWLVDLNPVCGHEQADRRPALVVSVDGFNHG-PAGLVIVIPITTKDKGIPLH 59
Query 61 PPVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
V P E G+ S C VR+VA+ RLV LG ++ T+ E+ L ++LGL
Sbjct 60 VGVFPPEGGLNEQSFIKCEDVRSVAKERLVRCLGRVEERTLAEAEDRLRILLGL 113
>gi|312792908|ref|YP_004025831.1| transcriptional modulator of maze/toxin, mazf [Caldicellulosiruptor
kristjanssonii 177R1B]
gi|344996890|ref|YP_004799233.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
lactoaceticus 6A]
gi|312180048|gb|ADQ40218.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
kristjanssonii 177R1B]
gi|343965109|gb|AEM74256.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
lactoaceticus 6A]
Length=112
Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 40/111 (37%), Positives = 63/111 (57%), Gaps = 2/111 (1%)
Query 4 PRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPV 63
PRRG++WLV L R E RPAV+VSVDE + D LV+VV + S PL +
Sbjct 3 PRRGEIWLVDLNPTRGHEQSGIRPAVIVSVDEFNSCPAD-LVIVVSIMSKNKNIPLHVEI 61
Query 64 AP-SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P + G+ S A +R++++ RLV ++G L ++ +E + ++LG+
Sbjct 62 QPENSGLTKVSFAKPEDIRSISKERLVRKIGQLPKERLKELEEKIRILLGV 112
>gi|312128613|ref|YP_003993487.1| transcriptional modulator of maze/toxin, mazf [Caldicellulosiruptor
hydrothermalis 108]
gi|311778632|gb|ADQ08118.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
hydrothermalis 108]
Length=112
Score = 70.9 bits (172), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 41/112 (37%), Positives = 64/112 (58%), Gaps = 2/112 (1%)
Query 3 EPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPP 62
P RG++WLV L R E RPAV++SVDE +LVVVVP++S PL
Sbjct 2 NPARGEIWLVDLNPTRGHEQSGVRPAVIISVDE-FNSCPADLVVVVPITSKNKNIPLHVE 60
Query 63 VAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ P G+A S A +R++++ RLV+++G L ++ +E + ++LGL
Sbjct 61 IQPEHSGLAKTSFAKLEDIRSISKERLVKKIGQLPKEKLKEMEEKVRILLGL 112
>gi|344997339|ref|YP_004799682.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
lactoaceticus 6A]
gi|343965558|gb|AEM74705.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
lactoaceticus 6A]
Length=112
Score = 70.1 bits (170), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 41/112 (37%), Positives = 65/112 (59%), Gaps = 2/112 (1%)
Query 3 EPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPP 62
P RG++WLV L R E RPAV++SVDE + D LVVVVP++S P+
Sbjct 2 NPTRGEIWLVDLNPTRGHEQSGVRPAVIISVDEFNSCPAD-LVVVVPITSKNKNIPMHVE 60
Query 63 VAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ P G+A S A +R++++ RLV+++G L ++ +E + ++LGL
Sbjct 61 IQPEHSGLAKTSFAKPEDIRSISKERLVKKIGQLPKEKLKEMEEKIRILLGL 112
>gi|148264028|ref|YP_001230734.1| transcriptional modulator of MazE/toxin, MazF [Geobacter uraniireducens
Rf4]
gi|146397528|gb|ABQ26161.1| transcriptional modulator of MazE/toxin, MazF [Geobacter uraniireducens
Rf4]
Length=114
Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 43/114 (38%), Positives = 59/114 (52%), Gaps = 8/114 (7%)
Query 4 PRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSS----RSRTPL 59
P R ++WL L R E RP ++VSVD L EL +V+P++S RS PL
Sbjct 5 PARAEIWLADLNPTRGREQAGMRPCLIVSVD-LFNQSPAELAIVIPITSRNKGIRSHVPL 63
Query 60 RPPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
PP GV S C VR+++ RLV R G + A MR +E L +++GL
Sbjct 64 VPPEG---GVREPSYIKCEDVRSISSERLVTRWGKISDAVMRDVEYRLRILMGL 114
>gi|166368979|ref|YP_001661252.1| PemK-like protein [Microcystis aeruginosa NIES-843]
gi|166091352|dbj|BAG06060.1| PemK-like protein [Microcystis aeruginosa NIES-843]
Length=113
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/114 (36%), Positives = 59/114 (52%), Gaps = 2/114 (1%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLR 60
+AE RG++WL L R E RP +V+S D G LVVV+PV+S P
Sbjct 1 MAEITRGEIWLADLNPVRGHEQAGKRPCLVISADLFNQGASG-LVVVLPVTSKDKGIPFH 59
Query 61 PPVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
V P E GV S C VR+++ RL +R G + T+ +E+ L +++GL
Sbjct 60 IKVEPPEGGVKMPSFIKCEDVRSISVERLEKRWGTVSSETLALVEDRLRILMGL 113
>gi|312794276|ref|YP_004027199.1| transcriptional modulator of maze/toxin, mazf [Caldicellulosiruptor
kristjanssonii 177R1B]
gi|312181416|gb|ADQ41586.1| transcriptional modulator of MazE/toxin, MazF [Caldicellulosiruptor
kristjanssonii 177R1B]
Length=112
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 38/110 (35%), Positives = 64/110 (59%), Gaps = 2/110 (1%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RG++WLV L R E RPAV++SV+E +LVVVVP++S PL +
Sbjct 4 KRGEIWLVDLNPTRGHEQSGIRPAVIISVNE-FNSCPADLVVVVPITSKNKNIPLHVEIQ 62
Query 65 P-SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P + G+ S A +R++++ RLV+++G L ++ +E + ++LGL
Sbjct 63 PENSGLTKVSFAKPEDIRSISKERLVKKIGQLPKEKLKELEEKIRILLGL 112
>gi|297660628|ref|YP_003710339.1| putative mazF-like toxin [Waddlia chondrophila WSU 86-1044]
gi|297377504|gb|ADI39333.1| putative mazF-like toxin [Waddlia chondrophila WSU 86-1044]
Length=121
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 37/100 (37%), Positives = 61/100 (61%), Gaps = 3/100 (3%)
Query 3 EPRRGDLWLVSLGAARAGEPGKH-RPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRP 61
P +G++WL + E GK RPA+VVS + + G+ L+++VP++S + P
Sbjct 7 NPLQGEVWLFDPDPVKGNEIGKKVRPALVVSNNLMNKGVSG-LIIIVPITSKDKKIPSHI 65
Query 62 PVAPSEG-VAADSVAVCRGVRAVARARLVERLGALKPATM 100
+ P EG V S AVC VR+++++RLV+RLG ++ AT+
Sbjct 66 RIEPPEGGVNLPSFAVCEQVRSISKSRLVKRLGKVQSATV 105
>gi|256396397|ref|YP_003117961.1| transcriptional modulator of MazE/toxin, MazF [Catenulispora
acidiphila DSM 44928]
gi|256362623|gb|ACU76120.1| transcriptional modulator of MazE/toxin, MazF [Catenulispora
acidiphila DSM 44928]
Length=123
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 47/115 (41%), Positives = 66/115 (58%), Gaps = 6/115 (5%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDE---LVVVVPVSSSRSRT-PLR 60
RRGD+ V+L AR GE K RPAVVVS D + + + +V VVPV+S+ R P +
Sbjct 9 RRGDMCWVNLDPARGGEIKKRRPAVVVSNDGVNSAVHRYGRGVVTVVPVTSNTERVYPFQ 68
Query 61 PPVAPSE--GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ ++ G+ DS A VR V AR+ R+ L P+TMR+++ AL L L L
Sbjct 69 ILIDAADHPGLRTDSKAQAEQVRTVDVARIGSRITTLSPSTMRSLDAALRLHLAL 123
>gi|153876884|ref|ZP_02003975.1| PemK-like protein [Beggiatoa sp. PS]
gi|152066651|gb|EDN66024.1| PemK-like protein [Beggiatoa sp. PS]
Length=117
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (56%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RG++WL L R E RP ++ ++LL + V+ +P++++ R L +
Sbjct 4 KRGEIWLAELNPTRGSEQAGTRPVLIFQ-NDLLNPLTTT-VLAIPMTTNLRRALLSSCLQ 61
Query 65 PSEG---VAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPT 115
S+G +A+DSVA+C R + + RL +LG++ P T+ AIE + LG+ T
Sbjct 62 ISKGEGGLASDSVALCHQFRVLDKTRLQHKLGSVTPQTIAAIETCMLFTLGVIT 115
>gi|168699546|ref|ZP_02731823.1| PemK-like protein [Gemmata obscuriglobus UQM 2246]
Length=96
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 39/97 (41%), Positives = 58/97 (60%), Gaps = 3/97 (3%)
Query 1 LAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRT-PL 59
+ P RG++W++ L R E RPA+++SVD + ELVVV+PV+S + P
Sbjct 1 MTAPVRGEVWMLDLSPVRGHEQQGTRPALILSVDAFNSS-KAELVVVLPVTSKKKYALPT 59
Query 60 RPPVAPSE-GVAADSVAVCRGVRAVARARLVERLGAL 95
P+ P E G+ SV +C VRAV++ RL+ RLGA+
Sbjct 60 HIPLDPPEGGLTMPSVVLCDQVRAVSKDRLIRRLGAV 96
>gi|297621433|ref|YP_003709570.1| putative mazF-like toxin [Waddlia chondrophila WSU 86-1044]
gi|297376734|gb|ADI38564.1| putative mazF-like toxin [Waddlia chondrophila WSU 86-1044]
Length=121
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/100 (37%), Positives = 58/100 (58%), Gaps = 3/100 (3%)
Query 3 EPRRGDLWLVSLGAARAGEPGKH-RPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRP 61
P +G++WL + E GK RPA+VVS + L+ L++VVP++S + P
Sbjct 7 HPLQGEIWLFDPDPVKGNEIGKKVRPALVVS-NNLMNKGASGLIIVVPITSKDKKIPSHI 65
Query 62 PVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATM 100
+ P E GV S AVC VR++++ RLV+RLG ++ T+
Sbjct 66 RIDPPEGGVNLSSFAVCEQVRSISKNRLVKRLGKIQSVTV 105
>gi|320161823|ref|YP_004175048.1| putative endoribonuclease [Anaerolinea thermophila UNI-1]
gi|319995677|dbj|BAJ64448.1| putative endoribonuclease [Anaerolinea thermophila UNI-1]
Length=112
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 42/112 (38%), Positives = 62/112 (56%), Gaps = 8/112 (7%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRP--- 61
+RG++WLV+L E K RPAV+VS D L G+ L V+VP++ + R + P
Sbjct 2 KRGEVWLVNLDPTLGAEMRKSRPAVIVSSD--LVGVL-PLRVIVPLTDWKERYSVAPWMV 58
Query 62 --PVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLIL 111
A S G+ DS A C VR+V+ RLV ++G L P M I ++ L++
Sbjct 59 QIKAASSNGLDKDSAADCFQVRSVSTMRLVRKIGRLSPEDMEKIVQSIQLVV 110
>gi|307299621|ref|ZP_07579418.1| transcriptional modulator of MazE/toxin, MazF [Thermotogales
bacterium MesG1.Ag.4.2]
gi|306914757|gb|EFN45146.1| transcriptional modulator of MazE/toxin, MazF [Thermotogales
bacterium MesG1.Ag.4.2]
Length=115
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/111 (33%), Positives = 59/111 (54%), Gaps = 2/111 (1%)
Query 4 PRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPV 63
P RG++WL +L R E RP +V+SVD+ G ELV+VVP++S PL +
Sbjct 5 PSRGEIWLANLSPVRGREQAGFRPCLVISVDQFNHG-PAELVIVVPITSKNKSIPLHVEI 63
Query 64 APSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ E G+ S VR+++R RL +R+G + M + + ++L +
Sbjct 64 SGRETGLDLTSYIKSEDVRSISRERLEKRIGRVSDEVMSQVLEVIKILLDI 114
>gi|37520200|ref|NP_923577.1| hypothetical protein glr0631 [Gloeobacter violaceus PCC 7421]
gi|35211193|dbj|BAC88572.1| glr0631 [Gloeobacter violaceus PCC 7421]
Length=105
Score = 61.2 bits (147), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 39/106 (37%), Positives = 57/106 (54%), Gaps = 2/106 (1%)
Query 9 LWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEG 68
+WL L R E RP +VVS D L G +LVVV+P++S P + P EG
Sbjct 1 MWLADLDPTRGREQAGRRPCLVVSADPLNRG-PAQLVVVLPITSRDKGIPFHVGLEPPEG 59
Query 69 -VAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
V S C VR+++ RL E+ GA++ T+ A+E+ L ++L L
Sbjct 60 GVTVRSFIKCEDVRSISTQRLTEKWGAVRNETLLAVEDRLRILLSL 105
>gi|269957099|ref|YP_003326888.1| transcriptional modulator of MazE/toxin, MazF [Xylanimonas cellulosilytica
DSM 15894]
gi|269305780|gb|ACZ31330.1| transcriptional modulator of MazE/toxin, MazF [Xylanimonas cellulosilytica
DSM 15894]
Length=117
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 43/115 (38%), Positives = 63/115 (55%), Gaps = 6/115 (5%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDE---LVVVVPVSSSRSRTPLRP 61
RRG++W V L R E K R V+VS D ++ +V VVP++SS +R P
Sbjct 2 RRGEVWTVELDPVRGSEASKTRRCVIVSRDASNKAVETHGRGVVTVVPLTSSVARVPPFQ 61
Query 62 PVAPSE---GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ P+E G+ DS A VRAV +R+V R+G L+ + A+++AL LGL
Sbjct 62 ALVPAEPGNGLDHDSKAQAEQVRAVDVSRMVARVGTLRSEHVGAVDDALITHLGL 116
>gi|268324783|emb|CBH38371.1| conserved hypothetical protein, PemK-like protein family [uncultured
archaeon]
Length=114
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 34/112 (31%), Positives = 60/112 (54%), Gaps = 5/112 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
RRG++WL +L R E RP ++ D L V+ +P++++ R L V+
Sbjct 4 RRGEIWLANLNPTRGSEQAGIRPVLIFQTD--LLNRFTTTVLTIPLTTNLRRASLPSCVS 61
Query 65 PSE---GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
S G+ +DSVA+C +R + ++RL +LG + T+ AIE+ + +G+
Sbjct 62 ISREEGGLVSDSVALCHQLRVLDKSRLQRKLGTVSQQTLSAIESRMLFTMGI 113
>gi|337293746|emb|CCB91733.1| mRNA interferase MazF [Waddlia chondrophila 2032/99]
Length=121
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 38/113 (34%), Positives = 65/113 (58%), Gaps = 4/113 (3%)
Query 4 PRRGDLWLVSLGAARAGEPGKH-RPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPP 62
P +G++WL + E GK RPA++VS + L+ L++VVP++S + P
Sbjct 8 PLQGEVWLFDPDPVKGNEIGKKVRPALIVS-NNLMNKGASGLIIVVPITSKDKKIPSHIR 66
Query 63 VAPSE-GVAADSVAVCRGVRAVARARLVERLGALKP-ATMRAIENALTLILGL 113
+ P E GV S AVC VR++++ RLV+RLG ++ A ++ + + L +L +
Sbjct 67 IDPPEGGVNLPSFAVCEQVRSISKNRLVKRLGKIQSVAVLKEVGSWLNDLLWM 119
>gi|328952780|ref|YP_004370114.1| transcriptional modulator of MazE/toxin, MazF [Desulfobacca acetoxidans
DSM 11109]
gi|328453104|gb|AEB08933.1| transcriptional modulator of MazE/toxin, MazF [Desulfobacca acetoxidans
DSM 11109]
Length=107
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/105 (40%), Positives = 54/105 (52%), Gaps = 5/105 (4%)
Query 3 EPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPP 62
E RRGD++LVSL + GE K RP +++S DEL T + +V P+++ P R P
Sbjct 2 EIRRGDVFLVSLDPPQGGEIQKTRPCIIISPDELNTHL--RTFIVAPLTTGGHPYPFRLP 59
Query 63 VAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENAL 107
EG A V +R V R RLV RLG L P + I L
Sbjct 60 CQ-FEGKAG--FVVLDQIRTVDRGRLVRRLGELPPDVLGRILETL 101
>gi|120402156|ref|YP_951985.1| transcriptional modulator of MazE/toxin, MazF [Mycobacterium
vanbaalenii PYR-1]
gi|119954974|gb|ABM11979.1| transcriptional modulator of MazE/toxin, MazF [Mycobacterium
vanbaalenii PYR-1]
Length=115
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 42/114 (37%), Positives = 64/114 (57%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDE---LLTGIDDELVVVVPVSSSRSRT-PLR 60
+RGD+W V L +RA E K RPAV+VS D + + ++ VVPV+S+ R P +
Sbjct 2 QRGDIWYVDLEPSRASEANKTRPAVIVSNDRANATASRLGRGVISVVPVTSNVDRVYPFQ 61
Query 61 PPV-APSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ AP G+A S A VR++A RL+ R+G + + +++AL L L L
Sbjct 62 VLLQAPDSGLAVASKAQAEQVRSIAAQRLIRRIGRVSARELAELDDALRLHLAL 115
>gi|334116633|ref|ZP_08490725.1| transcriptional modulator of MazE/toxin, MazF [Microcoleus vaginatus
FGP-2]
gi|333461453|gb|EGK90058.1| transcriptional modulator of MazE/toxin, MazF [Microcoleus vaginatus
FGP-2]
Length=113
Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 44/114 (39%), Positives = 61/114 (54%), Gaps = 8/114 (7%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
RRG++WLV+L E GK RP V+VS DE + GI L V+VP++ + R R +
Sbjct 2 RRGEIWLVALEPTVGAEIGKTRPVVIVS-DETV-GI-LLLEVIVPITDWKERYTERNWMV 58
Query 65 PSE-----GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
E G+ S A VR+V++ R V +LG L M I ALT++L L
Sbjct 59 RLEPSGENGLTKVSAADTFQVRSVSQQRFVRQLGTLSETIMEEIAEALTIVLDL 112
>gi|333992725|ref|YP_004525339.1| hypothetical protein JDM601_4085 [Mycobacterium sp. JDM601]
gi|333488693|gb|AEF38085.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=115
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 44/114 (39%), Positives = 60/114 (53%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTG---IDDELVVVVPVSSSRSRT-PLR 60
RRGD+W V R E K+RPAVVVS D + +V VVPV+S+ + P +
Sbjct 2 RRGDIWQVDFDPTRGSEANKYRPAVVVSNDRANATAGRLGRGVVTVVPVTSNTATVYPFQ 61
Query 61 PPV-APSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ A S G+A DS A +R+VA RL R+G L + ++ AL L L L
Sbjct 62 VLLPATSTGLAVDSKAQAEQIRSVAVERLQRRIGRLPAIELTQLDEALRLHLDL 115
>gi|134097900|ref|YP_001103561.1| hypothetical protein SACE_1313 [Saccharopolyspora erythraea NRRL
2338]
gi|291007382|ref|ZP_06565355.1| hypothetical protein SeryN2_22897 [Saccharopolyspora erythraea
NRRL 2338]
gi|133910523|emb|CAM00636.1| hypothetical protein SACE_1313 [Saccharopolyspora erythraea NRRL
2338]
Length=115
Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 44/114 (39%), Positives = 64/114 (57%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDE---LVVVVPVSSSRSRT-PLR 60
RRGD++ V R E K RPAVVVS D + ++ VVP++S+ +R P +
Sbjct 2 RRGDVYWVDFEPIRGSEADKTRPAVVVSNDAANRSAERARRGVITVVPLTSNVNRVLPFQ 61
Query 61 PPVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ ++ G+A DS A VRAVA RL +R+G + T+ ++NAL L LGL
Sbjct 62 VRLRAADCGLAGDSKAQAEQVRAVAFHRLGKRIGRVPDTTLAKLDNALRLHLGL 115
>gi|91203966|emb|CAJ71619.1| similar to YdcE protein, chain A [Candidatus Kuenenia stuttgartiensis]
Length=117
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 37/114 (33%), Positives = 56/114 (50%), Gaps = 6/114 (5%)
Query 4 PRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSR--SRTPLRP 61
P++GD++LV L E K RP V++S D G V +VP++SS P
Sbjct 6 PKQGDIYLVVLDPTIGTEMAKTRPGVIISNDHANKG--SNRVSIVPITSSNVVKVYPFEV 63
Query 62 --PVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P + DS C VR++ + RL+++LG++ TM I+ AL L L
Sbjct 64 FLPAKSESSLTCDSKIACDQVRSIDKRRLLKKLGSVSYDTMEGIKAALRLHFAL 117
>gi|186682027|ref|YP_001865223.1| MazF family transcripitonal regulator [Nostoc punctiforme PCC
73102]
gi|186464479|gb|ACC80280.1| transcriptional modulator of MazE/toxin, MazF [Nostoc punctiforme
PCC 73102]
Length=117
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/113 (35%), Positives = 62/113 (55%), Gaps = 8/113 (7%)
Query 6 RGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAP 65
RG++WLV+L E K RP ++V+ D + GI L V+VPV+ + R +RP +
Sbjct 3 RGEVWLVNLDPTVGTEISKKRPCIIVNDDAI--GI-LPLKVIVPVTDWKERYAVRPWMVR 59
Query 66 SEGVAADSVAVCRGV-----RAVARARLVERLGALKPATMRAIENALTLILGL 113
E +S+A GV R+V+ RLV +LG + + M+ I AL ++L +
Sbjct 60 LEPSTENSLAKVSGVDTFQIRSVSETRLVRKLGQISDSEMQLICQALAVVLNI 112
>gi|311746303|ref|ZP_07720088.1| toxin-antitoxin system, toxin component, MazF family [Algoriphagus
sp. PR1]
gi|126576538|gb|EAZ80816.1| toxin-antitoxin system, toxin component, MazF family [Algoriphagus
sp. PR1]
Length=113
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 33/111 (30%), Positives = 56/111 (51%), Gaps = 4/111 (3%)
Query 6 RGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSS--SRSRTPLRPPV 63
+ D+WLV+L AR EPGK RP+V++ + LL + ++ P++S S LR V
Sbjct 4 QFDIWLVNLNPARGTEPGKIRPSVIIQTN-LLNQVGHPSTLICPITSQISEDENILRVKV 62
Query 64 APSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
E G+ DS + +RA+ R +E+LG + ++ L ++
Sbjct 63 DQKETGLDQDSEILVDQIRALDNRRFLEKLGKISKEKALELQEKLKALMDF 113
>gi|339501431|ref|YP_004699466.1| transcriptional modulator of MazE/toxin, MazF [Spirochaeta caldaria
DSM 7334]
gi|338835780|gb|AEJ20958.1| transcriptional modulator of MazE/toxin, MazF [Spirochaeta caldaria
DSM 7334]
Length=113
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 33/111 (30%), Positives = 55/111 (50%), Gaps = 4/111 (3%)
Query 6 RGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSR--SRTPLRPPV 63
RG++W G EPG HRP +++ D+ + V+V+P +++ + +P V
Sbjct 3 RGEIWWADFGIPFGSEPGFHRPVLIIQ-DDSFNRSNINTVIVIPFTTNTILADSPGNVYV 61
Query 64 APSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
E G++ DSV V + + + RLV L + M +E + LILGL
Sbjct 62 ETIESGLSKDSVLVVSQISVLDKTRLVSLENKLHYSVMEEVEEGIKLILGL 112
>gi|164688914|ref|ZP_02212942.1| hypothetical protein CLOBAR_02562 [Clostridium bartlettii DSM
16795]
gi|164602118|gb|EDQ95583.1| hypothetical protein CLOBAR_02562 [Clostridium bartlettii DSM
16795]
Length=121
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 33/118 (28%), Positives = 61/118 (52%), Gaps = 11/118 (9%)
Query 2 AEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDEL---VVVVPVSS--SRSR 56
+E RRGDL+ L E G RP +V+ I ++ +++ ++S ++++
Sbjct 6 SEIRRGDLYYADLSPVVGSEQGGVRPVLVIQ-----NNIGNKYSPTIIIAAITSQINKAK 60
Query 57 TPLRPPVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P ++ +E G+ DSV + +R + + RL E++G L M I+N+L + LGL
Sbjct 61 LPTHIEISANEYGLNKDSVILLEQIRTIDKKRLREKIGCLDKNMMLKIDNSLQISLGL 118
>gi|254431259|ref|ZP_05044962.1| PemK-like protein [Cyanobium sp. PCC 7001]
gi|197625712|gb|EDY38271.1| PemK-like protein [Cyanobium sp. PCC 7001]
Length=117
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 40/113 (36%), Positives = 59/113 (53%), Gaps = 1/113 (0%)
Query 6 RGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAP 65
RG + LV L R E RP VVVS + + L+ VVPV+ + + L P +AP
Sbjct 5 RGTVVLVDLEPTRGHEQQGTRPCVVVSDAAVNSNQRFPLIAVVPVTGTPAPGALYPALAP 64
Query 66 -SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGP 117
+ G++ S A+ VR++ + R+ R G + A + AI+N L L LGL P
Sbjct 65 GASGLSKPSTALVDQVRSIDKQRIRRRYGQVSAAELEAIDNGLCLYLGLDPDP 117
>gi|315636800|ref|ZP_07892026.1| PemK family transcriptional regulator [Arcobacter butzleri JV22]
gi|315478926|gb|EFU69633.1| PemK family transcriptional regulator [Arcobacter butzleri JV22]
Length=113
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 33/106 (32%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query 6 RGDLWLVSLGAARA-GEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSS--RSRTPLRPP 62
RG++WLV+L ++ E K RP VV +EL D +++P+S+S PLR
Sbjct 5 RGEIWLVNLNPSKKPNEMSKVRPVVVFQNNEL-NHSDYPTTIIIPLSTSLVDDTEPLRMR 63
Query 63 VAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALT 108
+ E + DS V +RA+ R +++L L P M ++ L
Sbjct 64 ILKREDLEKDSDIVVTQIRAIDNDRFMQKLATLTPKEMDKLKQLLN 109
>gi|164515861|emb|CAP48095.1| putative integron gene cassette protein [uncultured bacterium]
Length=108
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 40/111 (37%), Positives = 59/111 (54%), Gaps = 4/111 (3%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RGD+W VS + GE K RPAV+VS D ++ V VVP++S+ +R L P A
Sbjct 2 KRGDVWWVSFDPSVGGEIRKRRPAVIVSNDASNQHLNR--VQVVPLTSNVAR--LYPSEA 57
Query 65 PSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPT 115
A+ + V++ RL RLG + A +R IE A+ + L LP+
Sbjct 58 YVTLCGEQRKAMADQLTTVSKVRLSGRLGEISAADLRGIERAIKVQLALPS 108
>gi|320326762|gb|EFW82805.1| plasmid maintenance protein [Pseudomonas syringae pv. glycinea
str. race 4]
gi|330892210|gb|EGH24871.1| plasmid maintenance protein [Pseudomonas syringae pv. mori str.
301020]
Length=108
Score = 54.3 bits (129), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 40/109 (37%), Positives = 56/109 (52%), Gaps = 4/109 (3%)
Query 6 RGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAP 65
RG++W V + E K RPAV+VS D + VVVVP++SS RT +
Sbjct 3 RGEVWWVEFDPSVGSEIKKTRPAVIVSNDSANRHL--ARVVVVPLTSSTERTYPGEALIT 60
Query 66 SEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLP 114
EG S A+ + A + RL RLG L M A+ENA+++ L +P
Sbjct 61 LEG--QSSKAMADQIMAADKKRLKNRLGKLSKVDMVAVENAISVHLAMP 107
>gi|166364143|ref|YP_001656416.1| PemK-like protein [Microcystis aeruginosa NIES-843]
gi|166086516|dbj|BAG01224.1| PemK-like protein [Microcystis aeruginosa NIES-843]
Length=118
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 30/111 (28%), Positives = 55/111 (50%), Gaps = 5/111 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVA 64
+RG++WL L + E RP ++ D L ++ +P+++++ R L +
Sbjct 7 KRGEVWLADLNPTQGSEEAGIRPVIIFQND--LVSQFSTTIIAIPLTTNQRRAALPICLL 64
Query 65 PSEG---VAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILG 112
+G + DSVA+C +R + + RL+ LG L P + +E + L LG
Sbjct 65 IEQGNGGLGQDSVALCFQMRVLDKTRLIRTLGQLSPEIIAQLEEVVLLTLG 115
>gi|224477058|ref|YP_002634664.1| hypothetical protein Sca_1574 [Staphylococcus carnosus subsp.
carnosus TM300]
gi|222421665|emb|CAL28479.1| conserved hypothetical protein [Staphylococcus carnosus subsp.
carnosus TM300]
Length=115
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 36/113 (32%), Positives = 56/113 (50%), Gaps = 7/113 (6%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSR---SRTPLRP 61
RRGD++L L + E G RP V++ D TG V+V + R ++ P
Sbjct 2 RRGDVYLADLSPVQGSEQGGVRPVVIIQND---TGNKYSPTVIVAAITGRINKAKIPTHV 58
Query 62 PVAPSE-GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ S+ + DSV + +R V + RL E+L L M+ I+NA+ + LGL
Sbjct 59 EIEKSKYKLDKDSVILLEQIRTVDKKRLKEKLTYLSDEKMKEIDNAIQISLGL 111
>gi|256848378|ref|ZP_05553821.1| regulatory protein [Lactobacillus coleohominis 101-4-CHN]
gi|256714976|gb|EEU29954.1| regulatory protein [Lactobacillus coleohominis 101-4-CHN]
Length=116
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 31/114 (28%), Positives = 58/114 (51%), Gaps = 5/114 (4%)
Query 3 EPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSS--SRSRTPLR 60
+ +RG ++ L E G RP V+V D + + ++V P+++ + R P
Sbjct 4 QIQRGAIYYARLSPVIGSEQGGFRPVVIVQND--VGNLHSPTMIVAPITAQMQKHRLPTH 61
Query 61 PPVAPS-EGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P+ + +G+ DS + +R + + RL +++G L ATM+A+ AL + L L
Sbjct 62 VPIKQNVKGIKRDSQILLEQIRTIDKQRLADQIGQLNQATMKAVNQALQVSLSL 115
>gi|340627801|ref|YP_004746253.1| hypothetical protein MCAN_28281 [Mycobacterium canettii CIPT
140010059]
gi|340005991|emb|CCC45159.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=118
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 39/114 (35%), Positives = 61/114 (54%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDE---LLTGIDDELVVVVPVSSSRSRT-PLR 60
RRG++W V L AR E K RPAVVVS D T + ++ VVPV+S+ ++ P +
Sbjct 3 RRGEIWQVDLDPARGSEANKQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQ 62
Query 61 PPV-APSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ A + G+ D A +R++A RL+ +G + + ++ AL L L L
Sbjct 63 VLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAVELAQLDEALKLHLDL 116
>gi|15842339|ref|NP_337376.1| hypothetical protein MT2869 [Mycobacterium tuberculosis CDC1551]
gi|254365452|ref|ZP_04981497.1| conserved hypothetical protein [Mycobacterium tuberculosis str.
Haarlem]
gi|289553412|ref|ZP_06442622.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
29 more sequence titles
Length=117
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 39/114 (35%), Positives = 61/114 (54%), Gaps = 5/114 (4%)
Query 5 RRGDLWLVSLGAARAGEPGKHRPAVVVSVDE---LLTGIDDELVVVVPVSSSRSRT-PLR 60
RRG++W V L AR E RPAVVVS D T + ++ VVPV+S+ ++ P +
Sbjct 2 RRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQ 61
Query 61 PPV-APSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
+ A + G+ D A +R++A RL+ +G + A + ++ AL L L L
Sbjct 62 VLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAAELAQLDEALKLHLDL 115
>gi|325282447|ref|YP_004254988.1| transcriptional modulator of MazE/toxin, MazF [Deinococcus proteolyticus
MRP]
gi|324314256|gb|ADY25371.1| transcriptional modulator of MazE/toxin, MazF [Deinococcus proteolyticus
MRP]
Length=114
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/112 (33%), Positives = 60/112 (54%), Gaps = 5/112 (4%)
Query 5 RRGDLWLVSLG-AARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPV 63
RRGD+WL++ R GE + P V+VS + G L++ VP++S+ R + +
Sbjct 5 RRGDIWLINYRPDGREGEAAQVHPGVIVSNNANNAGA--HLLMTVPLTSNVERVYVTNVI 62
Query 64 APSE--GVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGL 113
P++ G+ DS A +RA +RL++RLG + M ++ L + LGL
Sbjct 63 LPNQRTGLDHDSKAQVEAMRAAHASRLIKRLGHVPDDLMAELDGKLRMHLGL 114
Lambda K H
0.317 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 128858389450
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40