BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2064 Length=363 Score E Sequences producing significant alignments: (Bits) Value gi|308232020|ref|ZP_07414639.2| cobalamin biosynthesis protein c... 702 0.0 gi|15609201|ref|NP_216580.1| cobalamin biosynthesis protein CobG... 700 0.0 gi|289570174|ref|ZP_06450401.1| cobalamin biosynthesis protein c... 609 2e-172 gi|340627075|ref|YP_004745527.1| putative cobalamin biosynthesis... 582 2e-164 gi|308403444|ref|ZP_07493817.2| hypothetical protein TMLG_03556 ... 531 5e-149 gi|289758184|ref|ZP_06517562.1| cobalamin biosynthesis protein c... 509 2e-142 gi|183983045|ref|YP_001851336.1| cobalamin biosynthesis protein ... 508 9e-142 gi|118617805|ref|YP_906137.1| cobalamin biosynthesis protein [My... 505 6e-141 gi|240172452|ref|ZP_04751111.1| cobalamin biosynthesis protein [... 503 3e-140 gi|342859781|ref|ZP_08716434.1| CobG [Mycobacterium colombiense ... 501 1e-139 gi|254775097|ref|ZP_05216613.1| CobG [Mycobacterium avium subsp.... 489 4e-136 gi|41407908|ref|NP_960744.1| CobG [Mycobacterium avium subsp. pa... 488 8e-136 gi|336462047|gb|EGO40893.1| precorrin-3B synthase [Mycobacterium... 485 4e-135 gi|296165156|ref|ZP_06847705.1| cobalamin biosynthesis protein C... 483 3e-134 gi|298525567|ref|ZP_07012976.1| cobalamin biosynthesis protein [... 459 5e-127 gi|167967795|ref|ZP_02550072.1| cobalamin biosynthesis protein c... 446 3e-123 gi|315444020|ref|YP_004076899.1| precorrin-3B synthase [Mycobact... 432 3e-119 gi|145223693|ref|YP_001134371.1| precorrin-3B synthase [Mycobact... 429 4e-118 gi|108799456|ref|YP_639653.1| precorrin-3B synthase [Mycobacteri... 427 2e-117 gi|118467354|ref|YP_888162.1| precorrin-3B synthase [Mycobacteri... 422 4e-116 gi|120404401|ref|YP_954230.1| precorrin-3B synthase [Mycobacteri... 416 4e-114 gi|289443568|ref|ZP_06433312.1| cobalamin biosynthesis protein c... 365 5e-99 gi|111017194|ref|YP_700166.1| ferredoxin--nitrite reductase [Rho... 359 3e-97 gi|226359706|ref|YP_002777484.1| precorrin-3B synthase [Rhodococ... 358 8e-97 gi|305407946|dbj|BAJ15903.1| ferredoxin-nitrite reductase [Rhodo... 357 1e-96 gi|169629286|ref|YP_001702935.1| cobalamin biosynthesis protein ... 345 6e-93 gi|325676798|ref|ZP_08156471.1| cobalamin biosynthesis protein [... 331 1e-88 gi|312139750|ref|YP_004007086.1| precorrin-3b synthase cobg [Rho... 329 4e-88 gi|229493617|ref|ZP_04387402.1| precorrin-3B synthase [Rhodococc... 328 7e-88 gi|333919709|ref|YP_004493290.1| ferredoxin-nitrite reductase [A... 328 1e-87 gi|226306629|ref|YP_002766589.1| precorrin-3B synthase [Rhodococ... 325 5e-87 gi|54025109|ref|YP_119351.1| hypothetical protein nfa31400 [Noca... 305 9e-81 gi|254819623|ref|ZP_05224624.1| CobG [Mycobacterium intracellula... 290 4e-76 gi|262202407|ref|YP_003273615.1| precorrin-3B synthase [Gordonia... 286 3e-75 gi|213965647|ref|ZP_03393841.1| precorrin-3B synthase [Corynebac... 282 6e-74 gi|337290702|ref|YP_004629723.1| cobalamin biosynthesis protein ... 269 5e-70 gi|334696815|gb|AEG81612.1| cobalamin biosynthesis protein [Cory... 268 9e-70 gi|343927919|ref|ZP_08767385.1| precorrin-3B synthase [Gordonia ... 266 4e-69 gi|302330711|gb|ADL20905.1| Precorrin-3B synthase [Corynebacteri... 260 3e-67 gi|300858441|ref|YP_003783424.1| cobalamin biosynthesis protein ... 259 4e-67 gi|326382301|ref|ZP_08203993.1| precorrin-3B synthase [Gordonia ... 256 3e-66 gi|72160722|ref|YP_288379.1| cobalamin biosynthesis protein CobG... 247 2e-63 gi|300788892|ref|YP_003769183.1| precorrin-3B synthase [Amycolat... 246 5e-63 gi|284989174|ref|YP_003407728.1| precorrin-3B synthase [Geoderma... 246 5e-63 gi|38233819|ref|NP_939586.1| hypothetical protein DIP1231 [Coryn... 244 1e-62 gi|284032966|ref|YP_003382897.1| precorrin-3B synthase [Kribbell... 243 3e-62 gi|289443567|ref|ZP_06433311.1| cobalamin biosynthesis protein c... 241 1e-61 gi|227488955|ref|ZP_03919271.1| precorrin-3B synthase [Corynebac... 240 3e-61 gi|296139897|ref|YP_003647140.1| precorrin-3B synthase [Tsukamur... 237 3e-60 gi|225021474|ref|ZP_03710666.1| hypothetical protein CORMATOL_01... 236 6e-60 >gi|308232020|ref|ZP_07414639.2| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis SUMu001] gi|308369611|ref|ZP_07418425.2| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis SUMu002] gi|308370906|ref|ZP_07423156.2| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis SUMu003] 19 more sequence titles Length=378 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/363 (100%), Positives = 363/363 (100%), Gaps = 0/363 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG Sbjct 16 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 75 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 76 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 135 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL Sbjct 136 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 195 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 240 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV Sbjct 196 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 255 Query 241 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 300 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN Sbjct 256 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 315 Query 301 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR Sbjct 316 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 375 Query 361 LRP 363 LRP Sbjct 376 LRP 378 >gi|15609201|ref|NP_216580.1| cobalamin biosynthesis protein CobG [Mycobacterium tuberculosis H37Rv] gi|15841553|ref|NP_336590.1| CobG-related protein [Mycobacterium tuberculosis CDC1551] gi|31793247|ref|NP_855740.1| cobalamin biosynthesis protein CobG [Mycobacterium bovis AF2122/97] 43 more sequence titles Length=363 Score = 700 bits (1807), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/363 (99%), Positives = 363/363 (100%), Gaps = 0/363 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +AGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG Sbjct 1 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL Sbjct 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 240 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV Sbjct 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 240 Query 241 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 300 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN Sbjct 241 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 300 Query 301 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR Sbjct 301 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 Query 361 LRP 363 LRP Sbjct 361 LRP 363 >gi|289570174|ref|ZP_06450401.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T17] gi|289543928|gb|EFD47576.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T17] Length=364 Score = 609 bits (1571), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 353/364 (97%), Positives = 355/364 (98%), Gaps = 1/364 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +AGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG Sbjct 1 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL Sbjct 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGV-ELGPSVRPVTKTPVGWIPQDDSRVTLGAA 239 IEVALRFVKIRETAWRVTELADIGELQ + RPVTKTPVGWIPQDDSRVTLGAA Sbjct 181 IEVALRFVKIRETAWRVTELADIGELQCRLSSWAHPFRPVTKTPVGWIPQDDSRVTLGAA 240 Query 240 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL 299 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL Sbjct 241 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL 300 Query 300 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR 359 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR Sbjct 301 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR 360 Query 360 RLRP 363 RLRP Sbjct 361 RLRP 364 >gi|340627075|ref|YP_004745527.1| putative cobalamin biosynthesis protein CobG [Mycobacterium canettii CIPT 140010059] gi|340005265|emb|CCC44419.1| putative cobalamin biosynthesis protein CobG [Mycobacterium canettii CIPT 140010059] Length=363 Score = 582 bits (1501), Expect = 2e-164, Method: Compositional matrix adjust. Identities = 313/363 (87%), Positives = 329/363 (91%), Gaps = 0/363 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +AGTRDADACPGALRPHQAADGALARIRLPGGMITA QLATLASVA+ FGSATLELT+RG Sbjct 1 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAEQLATLASVANRFGSATLELTSRG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGI DV VADA+A AGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 61 NVQLRGITDVTEVADALANAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 AEPRLA+LGGRFWFGLDDGRADVSGLGADVG V DG LL+TGRDTGVRV DV ETL Sbjct 121 CAEPRLAKLGGRFWFGLDDGRADVSGLGADVGAHVLDDGVALLITGRDTGVRVTDVTETL 180 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 240 IE+ALRFV+IR AWR TELAD L G ELG PV++ PVGWIPQDD RV LGAAV Sbjct 181 IEIALRFVEIRGNAWRATELADPCALLPGAELGARFAPVSRPPVGWIPQDDGRVALGAAV 240 Query 241 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 300 PLGVLPA+VA+ +AAIEAPLVITPWRSVL+CDLDD ADAALRVLAPLGLVFDE+SPWLN Sbjct 241 PLGVLPAQVAQYVAAIEAPLVITPWRSVLVCDLDDGVADAALRVLAPLGLVFDEHSPWLN 300 Query 301 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 ISACTGSPGCAHSAADVRADAARSL+VESAGHRHFVGCERACGSPPAGEVLVATGGGYRR Sbjct 301 ISACTGSPGCAHSAADVRADAARSLDVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 Query 361 LRP 363 LRP Sbjct 361 LRP 363 >gi|308403444|ref|ZP_07493817.2| hypothetical protein TMLG_03556 [Mycobacterium tuberculosis SUMu012] gi|308365715|gb|EFP54566.1| hypothetical protein TMLG_03556 [Mycobacterium tuberculosis SUMu012] Length=273 Score = 531 bits (1369), Expect = 5e-149, Method: Compositional matrix adjust. Identities = 272/273 (99%), Positives = 273/273 (100%), Gaps = 0/273 (0%) Query 91 VRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGAD 150 +RNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGAD Sbjct 1 MRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGAD 60 Query 151 VGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGV 210 VGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGV Sbjct 61 VGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGV 120 Query 211 ELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLI 270 ELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLI Sbjct 121 ELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLI 180 Query 271 CDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA 330 CDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA Sbjct 181 CDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA 240 Query 331 GHRHFVGCERACGSPPAGEVLVATGGGYRRLRP 363 GHRHFVGCERACGSPPAGEVLVATGGGYRRLRP Sbjct 241 GHRHFVGCERACGSPPAGEVLVATGGGYRRLRP 273 >gi|289758184|ref|ZP_06517562.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T85] gi|289713748|gb|EFD77760.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T85] Length=303 Score = 509 bits (1312), Expect = 2e-142, Method: Compositional matrix adjust. Identities = 260/260 (100%), Positives = 260/260 (100%), Gaps = 0/260 (0%) Query 104 GGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLL 163 GGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLL Sbjct 44 GGLADVRAWVGELDAAIRAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLL 103 Query 164 LTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTP 223 LTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTP Sbjct 104 LTGRDTGVRVADVAETLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTP 163 Query 224 VGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALR 283 VGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALR Sbjct 164 VGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALR 223 Query 284 VLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACG 343 VLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACG Sbjct 224 VLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACG 283 Query 344 SPPAGEVLVATGGGYRRLRP 363 SPPAGEVLVATGGGYRRLRP Sbjct 284 SPPAGEVLVATGGGYRRLRP 303 >gi|183983045|ref|YP_001851336.1| cobalamin biosynthesis protein [Mycobacterium marinum M] gi|183176371|gb|ACC41481.1| cobalamin biosynthesis protein [Mycobacterium marinum M] Length=369 Score = 508 bits (1307), Expect = 9e-142, Method: Compositional matrix adjust. Identities = 271/363 (75%), Positives = 295/363 (82%), Gaps = 5/363 (1%) Query 5 RDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQL 64 RDADACPGAL+ HQAADGAL R+RLPGG +TA QLA LA +++ SATLELTARGN+QL Sbjct 5 RDADACPGALQVHQAADGALVRVRLPGGRLTADQLAALARASNELASATLELTARGNLQL 64 Query 65 RGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 R I DV AVADA+A AGLLPS THERVRNIVASPLSGR GGLADV++WVGELDAAI AEP Sbjct 65 RAITDVMAVADAIANAGLLPSPTHERVRNIVASPLSGRVGGLADVQSWVGELDAAICAEP 124 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAETLIE 182 LA+LGGRFWF +DDGRADVSGLGADVGV V DG +LL GRDTGVR+A DV TL E Sbjct 125 LLAQLGGRFWFSIDDGRADVSGLGADVGVHVLADGCAVLLDGRDTGVRLAPDDVVPTLTE 184 Query 183 VALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPL 242 +A+RF +IR WRV EL D L G G VTK PVGWIPQ D RVTLGAAVPL Sbjct 185 LAVRFTQIRGNCWRVNELIDPSVLVPGAAPGSRFPAVTKAPVGWIPQRDGRVTLGAAVPL 244 Query 243 GVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNIS 302 G+LPARVAE LAAIEAP+ ITPWRSVL+ DLD+A AD ALRVLAPLGLVFDENSPWLN+S Sbjct 245 GILPARVAEFLAAIEAPIAITPWRSVLVFDLDEAIADTALRVLAPLGLVFDENSPWLNVS 304 Query 303 ACTGSPGCAHSAADVRADAARSLNVESAG---HRHFVGCERACGSPPAGEVLVATGGGYR 359 ACTGSPGCA SAADVRADAA S+ E+A HRHFVGCERACGSP AGEVLVAT GYR Sbjct 305 ACTGSPGCASSAADVRADAALSVRTEAAASGVHRHFVGCERACGSPLAGEVLVATAQGYR 364 Query 360 RLR 362 LR Sbjct 365 LLR 367 >gi|118617805|ref|YP_906137.1| cobalamin biosynthesis protein [Mycobacterium ulcerans Agy99] gi|118569915|gb|ABL04666.1| cobalamin biosynthesis protein [Mycobacterium ulcerans Agy99] Length=369 Score = 505 bits (1300), Expect = 6e-141, Method: Compositional matrix adjust. Identities = 269/363 (75%), Positives = 295/363 (82%), Gaps = 5/363 (1%) Query 5 RDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQL 64 RDADACPGAL+ HQAADGAL R+RLPGG +TA QLA LA +++ SATLELTARGN+QL Sbjct 5 RDADACPGALQVHQAADGALVRVRLPGGRLTADQLAALARASNELASATLELTARGNLQL 64 Query 65 RGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 R I DV AVADA+A AGLLPS THERVRNIVASPLSGR GGLAD+++WVGELDAAI AEP Sbjct 65 RAITDVMAVADAIANAGLLPSPTHERVRNIVASPLSGRVGGLADLQSWVGELDAAICAEP 124 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAETLIE 182 LA+LGGRFWF +DDGRADVSGLGADVGV V DG +LL GRDTGVR+A DV TL E Sbjct 125 LLAQLGGRFWFSIDDGRADVSGLGADVGVHVLADGCAVLLDGRDTGVRLAPDDVVPTLTE 184 Query 183 VALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPL 242 +A+RF ++R WRV EL D L G G VTK PVGWIPQ D RVTLGAAVPL Sbjct 185 LAVRFTQMRGNFWRVNELIDPSVLVPGAAPGSRFPAVTKAPVGWIPQRDGRVTLGAAVPL 244 Query 243 GVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNIS 302 G+LPARVAE LAAIEAP+ ITPWRSVL+ DLD+A AD ALRVLAPLGLVFDENSPWLN+S Sbjct 245 GILPARVAEFLAAIEAPIAITPWRSVLVFDLDEAIADTALRVLAPLGLVFDENSPWLNVS 304 Query 303 ACTGSPGCAHSAADVRADAARSLNVESAG---HRHFVGCERACGSPPAGEVLVATGGGYR 359 ACTGSPGCA SAADVRADAA S+ E+A HRHFVGCERACGSP AGEVLVAT GYR Sbjct 305 ACTGSPGCASSAADVRADAALSVRTEAAASGVHRHFVGCERACGSPLAGEVLVATAQGYR 364 Query 360 RLR 362 LR Sbjct 365 LLR 367 >gi|240172452|ref|ZP_04751111.1| cobalamin biosynthesis protein [Mycobacterium kansasii ATCC 12478] Length=368 Score = 503 bits (1294), Expect = 3e-140, Method: Compositional matrix adjust. Identities = 265/362 (74%), Positives = 299/362 (83%), Gaps = 0/362 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A +RD DACPGAL+ HQAADGAL R+RLPGG I AAQL LA ++ FGS TLELT+RG Sbjct 1 MARSRDTDACPGALQVHQAADGALVRVRLPGGRIAAAQLGVLAEASTRFGSGTLELTSRG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGI +VA VA A+A+AGLLPSATHERVRNIVASPLSGRAGG AD+R WV ELDAAI Sbjct 61 NVQLRGITEVATVAAAIAEAGLLPSATHERVRNIVASPLSGRAGGNADIRDWVDELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 AEPRLA LGGRFWF LDDGR DVSGL ADVGV V+ DG L L GRDTG RV DV TL Sbjct 121 CAEPRLAGLGGRFWFSLDDGRGDVSGLAADVGVHVYDDGCALTLAGRDTGTRVGDVTATL 180 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAV 240 + +ALRF+++R WR+TEL+D+ L G++ G + P T PVGWI QDD RVT+GAAV Sbjct 181 VRMALRFIEVRGKHWRITELSDLDVLLPGMQPGAAFPPATMPPVGWIAQDDGRVTVGAAV 240 Query 241 PLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLN 300 PLGVLPAR+AE +AAIEAPLV+TPWRS+LICDLD+A AD LRVLAPLGLVFDENSPWL Sbjct 241 PLGVLPARIAEYVAAIEAPLVVTPWRSLLICDLDEAVADTVLRVLAPLGLVFDENSPWLR 300 Query 301 ISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRR 360 +SACTGSPGCA S ADVRADAAR L+ ++ GHRHFVGCERACGSP +GEVLVATG GYR Sbjct 301 VSACTGSPGCARSVADVRADAARELDADTVGHRHFVGCERACGSPLSGEVLVATGDGYRA 360 Query 361 LR 362 LR Sbjct 361 LR 362 >gi|342859781|ref|ZP_08716434.1| CobG [Mycobacterium colombiense CECT 3035] gi|342132913|gb|EGT86133.1| CobG [Mycobacterium colombiense CECT 3035] Length=364 Score = 501 bits (1289), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 274/364 (76%), Positives = 301/364 (83%), Gaps = 3/364 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A RD DACPGAL+ HQAADGALAR+RLPGGMITAAQLA LA+V+++ GS TLELTARG Sbjct 1 MARARDTDACPGALQVHQAADGALARVRLPGGMITAAQLAALAAVSNESGSGTLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRG+ DV AV +A+A AGLLPS THERVRNIVASPLSGR+GG DVR WVGELDAA+ Sbjct 61 NVQLRGLTDVTAVGEALAAAGLLPSTTHERVRNIVASPLSGRSGGNVDVRRWVGELDAAL 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAE 178 AEPRLAELGGRFWF LDDGR DVSGL ADVGV FPDG LLL GRDTGVR+A +V E Sbjct 121 CAEPRLAELGGRFWFSLDDGRGDVSGLRADVGVHAFPDGCALLLAGRDTGVRLAAGEVVE 180 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGVE-LGPSVRPVTKTPVGWIPQDDSRVTLG 237 TLI +A+RFV IR TAWRV EL D+ L G + + VT+ PVGWI Q+D RVTLG Sbjct 181 TLITLAMRFVDIRGTAWRVQELDDVRRLLPGADPHATAFSAVTRGPVGWIGQNDGRVTLG 240 Query 238 AAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSP 297 AAVPLG+LPA VAE LAAIEAP+VITPWRSVL+CDL + AD ALRVLAPLGLVFDENSP Sbjct 241 AAVPLGMLPAHVAEYLAAIEAPMVITPWRSVLVCDLSEEVADTALRVLAPLGLVFDENSP 300 Query 298 WLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGG 357 WL +SACTGSPGCA SAADVRADAA SL+ S HRHFVGCERACGSP AGEVLVAT G Sbjct 301 WLAVSACTGSPGCARSAADVRADAAHSLDAGSTVHRHFVGCERACGSPLAGEVLVATPDG 360 Query 358 YRRL 361 YRRL Sbjct 361 YRRL 364 >gi|254775097|ref|ZP_05216613.1| CobG [Mycobacterium avium subsp. avium ATCC 25291] Length=366 Score = 489 bits (1258), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 273/366 (75%), Positives = 301/366 (83%), Gaps = 4/366 (1%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A TRDADACPGAL+ HQAADGALAR+RLPGGM+T AQL L +A GS TLELTARG Sbjct 1 MARTRDADACPGALQVHQAADGALARVRLPGGMLTPAQLTVLCDIADRSGSPTLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRG+ DV A A A+A AGLLPSATHERVRNIVASPLSGR+GG DVR WVGELDAAI Sbjct 61 NVQLRGLTDVTAAAGALAAAGLLPSATHERVRNIVASPLSGRSGGNLDVRRWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAE 178 RA+PRLAELGGRFWF LDDGRADVSGL ADVGV PDG +LL GRDTGVR+ V Sbjct 121 RAQPRLAELGGRFWFSLDDGRADVSGLRADVGVHALPDGCAVLLAGRDTGVRLPPDQVVA 180 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP-VTKTPVGWIPQDDSRVTLG 237 TL+ VA RFV++R +AWRV EL D +L G E GP P VTK PVGWI QDD RVTLG Sbjct 181 TLVGVATRFVQVRGSAWRVQELDDPNQLLPGAECGPIAYPAVTKPPVGWITQDDGRVTLG 240 Query 238 AAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSP 297 AAVPLG+L ARVAE LAA++APLVITPWRSVL+ DL + ADAALRVLAPLGLVFDENSP Sbjct 241 AAVPLGLLSARVAEYLAALQAPLVITPWRSVLVGDLREEVADAALRVLAPLGLVFDENSP 300 Query 298 WLNISACTGSPGCAHSAADVRADAARSLNVESA-GHRHFVGCERACGSPPAGEVLVATGG 356 WL++SACTGSPGCA SAADVRADAA ++ +A GHRHFVGCERACGSP AGEVL+ATG Sbjct 301 WLSVSACTGSPGCARSAADVRADAALAVRDGTAPGHRHFVGCERACGSPLAGEVLLATGE 360 Query 357 GYRRLR 362 GYR+LR Sbjct 361 GYRQLR 366 >gi|41407908|ref|NP_960744.1| CobG [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396262|gb|AAS04127.1| CobG [Mycobacterium avium subsp. paratuberculosis K-10] Length=366 Score = 488 bits (1255), Expect = 8e-136, Method: Compositional matrix adjust. Identities = 271/366 (75%), Positives = 300/366 (82%), Gaps = 4/366 (1%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A TRDADACPGAL+ HQAADGALAR+RLPGGM+T AQL L +A GS TLELTARG Sbjct 1 MARTRDADACPGALQVHQAADGALARVRLPGGMLTPAQLTVLCDIADRLGSPTLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRG+ DV A A A+A AGLLPSATHERVRNIVASPLSGR+GG DVR WVGELDAAI Sbjct 61 NVQLRGLTDVTAAAGALAAAGLLPSATHERVRNIVASPLSGRSGGNLDVRRWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAE 178 RA+PRL+ELGGRFWF LDDGRADVSGL ADVGV V PDG +LL GRDT VR+ V Sbjct 121 RAQPRLSELGGRFWFSLDDGRADVSGLRADVGVHVLPDGCAVLLAGRDTAVRLPPDQVVA 180 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP-VTKTPVGWIPQDDSRVTLG 237 TL+ VA RFV++R +AWRV EL D +L G E GP P VTK PVGWI QDD RVTLG Sbjct 181 TLVGVATRFVQVRGSAWRVQELDDPNQLLPGAECGPIAYPAVTKPPVGWITQDDGRVTLG 240 Query 238 AAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSP 297 AAVPLG+L ARVAE LAA++APLVITPWRSVL+ DL + ADAALRVLAPLGLVFDENSP Sbjct 241 AAVPLGLLSARVAEYLAALQAPLVITPWRSVLVGDLREEVADAALRVLAPLGLVFDENSP 300 Query 298 WLNISACTGSPGCAHSAADVRADAARSLNVESA-GHRHFVGCERACGSPPAGEVLVATGG 356 WL++SACTGSPGCA S ADVRADAA ++ +A GHRHFVGCERACGSP AGEVL+ATG Sbjct 301 WLSVSACTGSPGCARSTADVRADAALAVREGTAPGHRHFVGCERACGSPLAGEVLLATGE 360 Query 357 GYRRLR 362 GYR+LR Sbjct 361 GYRQLR 366 >gi|336462047|gb|EGO40893.1| precorrin-3B synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=366 Score = 485 bits (1249), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 270/366 (74%), Positives = 299/366 (82%), Gaps = 4/366 (1%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A TRDADACPGAL+ HQAADGALAR+RLPGGM+T AQL L +A GS TLELTARG Sbjct 1 MARTRDADACPGALQVHQAADGALARVRLPGGMLTPAQLTVLCDIADRLGSPTLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRG+ DV A A A+A AGLLPSATHERVRNIVASPLSGR+GG DVR WVGELDAAI Sbjct 61 NVQLRGLTDVTAAAGALAAAGLLPSATHERVRNIVASPLSGRSGGNLDVRRWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAE 178 RA+PRL+ELGGRFWF LDDGRADVSGL ADVGV V PDG +LL GRDT VR+ V Sbjct 121 RAQPRLSELGGRFWFSLDDGRADVSGLRADVGVHVLPDGCAVLLAGRDTAVRLPPDQVVA 180 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP-VTKTPVGWIPQDDSRVTLG 237 TL+ VA R V++R +AWRV EL D +L G E GP P VTK PVGWI QDD RVTLG Sbjct 181 TLVGVATRLVQVRGSAWRVQELDDPNQLLPGAECGPIAYPAVTKPPVGWITQDDGRVTLG 240 Query 238 AAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSP 297 AAVPLG+L ARVAE LAA++APLVITPWRSVL+ DL + ADAALRVLAPLGLVFDENSP Sbjct 241 AAVPLGLLSARVAEYLAALQAPLVITPWRSVLVGDLREEVADAALRVLAPLGLVFDENSP 300 Query 298 WLNISACTGSPGCAHSAADVRADAARSLNVESA-GHRHFVGCERACGSPPAGEVLVATGG 356 WL++SACTGSPGCA S ADVRADAA ++ +A GHRHFVGCERACGSP AGEVL+ATG Sbjct 301 WLSVSACTGSPGCARSTADVRADAALAVREGTAPGHRHFVGCERACGSPLAGEVLLATGE 360 Query 357 GYRRLR 362 GYR+LR Sbjct 361 GYRQLR 366 >gi|296165156|ref|ZP_06847705.1| cobalamin biosynthesis protein CobG [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899500|gb|EFG78957.1| cobalamin biosynthesis protein CobG [Mycobacterium parascrofulaceum ATCC BAA-614] Length=365 Score = 483 bits (1242), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 276/365 (76%), Positives = 304/365 (84%), Gaps = 3/365 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A TR DACPGAL+ H+AADGALARIRLPGG +TAAQLA LA VAS++GS+TLELTARG Sbjct 1 MARTRGTDACPGALQVHRAADGALARIRLPGGALTAAQLAALARVASEYGSSTLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 N+Q+RGI D AA ADA+A AGLLPSATHERVRNIVASPLSGRAGG D R WV LDA I Sbjct 61 NIQVRGITDEAAAADAIAAAGLLPSATHERVRNIVASPLSGRAGGNVDARPWVAALDAVI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAE 178 AEPRLA LGGRFWF +DDGRADVSGL ADVGV VFPDG LLL GRDTGVR+ +V E Sbjct 121 CAEPRLAGLGGRFWFSVDDGRADVSGLCADVGVHVFPDGCALLLAGRDTGVRLGADEVVE 180 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP-VTKTPVGWIPQDDSRVTLG 237 TL +A RF R +AWRV EL D+ L GVELG + P VT+ PVGWI QD+ RV LG Sbjct 181 TLAVIATRFATTRGSAWRVKELDDLDALLPGVELGVAPFPAVTRPPVGWIAQDEGRVALG 240 Query 238 AAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSP 297 AAVPLGVL ARVAE LAAIEAPLVITPWRSVL+CDLD+A AD ALRVLAPLGLVFDENSP Sbjct 241 AAVPLGVLSARVAEYLAAIEAPLVITPWRSVLVCDLDEAVADVALRVLAPLGLVFDENSP 300 Query 298 WLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGG 357 WL++SACTGSPGCAHSAADVRADAA++L +S HRHFVGCERACGSP AGEVL+ATG G Sbjct 301 WLDVSACTGSPGCAHSAADVRADAAQALEADSGVHRHFVGCERACGSPLAGEVLLATGDG 360 Query 358 YRRLR 362 YR+LR Sbjct 361 YRQLR 365 >gi|298525567|ref|ZP_07012976.1| cobalamin biosynthesis protein [Mycobacterium tuberculosis 94_M4241A] gi|298495361|gb|EFI30655.1| cobalamin biosynthesis protein [Mycobacterium tuberculosis 94_M4241A] Length=250 Score = 459 bits (1180), Expect = 5e-127, Method: Compositional matrix adjust. Identities = 232/232 (100%), Positives = 232/232 (100%), Gaps = 0/232 (0%) Query 132 RFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIR 191 RFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIR Sbjct 19 RFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVALRFVKIR 78 Query 192 ETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAE 251 ETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAE Sbjct 79 ETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAE 138 Query 252 CLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCA 311 CLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCA Sbjct 139 CLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCA 198 Query 312 HSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRRLRP 363 HSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRRLRP Sbjct 199 HSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYRRLRP 250 >gi|167967795|ref|ZP_02550072.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis H37Ra] Length=365 Score = 446 bits (1147), Expect = 3e-123, Method: Compositional matrix adjust. Identities = 233/237 (99%), Positives = 234/237 (99%), Gaps = 0/237 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +AGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG Sbjct 1 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL Sbjct 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETL 180 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLG 237 IEVALRFV IRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRV G Sbjct 181 IEVALRFVNIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVNAG 237 >gi|315444020|ref|YP_004076899.1| precorrin-3B synthase [Mycobacterium sp. Spyr1] gi|315262323|gb|ADT99064.1| precorrin-3B synthase [Mycobacterium sp. Spyr1] Length=372 Score = 432 bits (1112), Expect = 3e-119, Method: Compositional matrix adjust. Identities = 237/364 (66%), Positives = 273/364 (75%), Gaps = 11/364 (3%) Query 5 RDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQL 64 R+ DACPGAL+ H+AADG L+RIRLPGG IT QL +A A D ++TLELT+RGN+Q+ Sbjct 5 REKDACPGALQTHRAADGDLSRIRLPGGAITPPQLEVVAQAAIDLAASTLELTSRGNLQI 64 Query 65 RGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 RG+RD AAVAD +A AGLLPSATHERVRNIVASPLSGR GGL DVRA V +LDAA++ +P Sbjct 65 RGVRDTAAVADLLAGAGLLPSATHERVRNIVASPLSGRHGGLCDVRALVADLDAAVQRDP 124 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVA--DVAETLI 181 LAEL GRF FG DDGR D+SGLGAD GV D LLL GRDTGVRVA + L+ Sbjct 125 VLAELPGRFLFGFDDGRGDISGLGADAGVHALDDSTAALLLAGRDTGVRVALSSAVDELL 184 Query 182 EVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP------VTKTPVGWIPQDDSRVT 235 VA RFV +R WRV EL D L G P+ RP T+ PVGWI Q D R+ Sbjct 185 AVARRFVDVRGKHWRVGELDDPAILLDG--RAPTERPGGTWQARTRPPVGWIEQTDGRIA 242 Query 236 LGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDEN 295 LGAAVPLGVL A+VA LAA+EAPL +TPWRSVLI DLD+ AD ALRVLAPLGL+FDE+ Sbjct 243 LGAAVPLGVLDAQVARYLAAVEAPLTVTPWRSVLIFDLDEGVADVALRVLAPLGLIFDED 302 Query 296 SPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATG 355 S WL++SACTGSPGCAHSAADVRADA +++ A HRHFVGC+RACGSP +VLVATG Sbjct 303 SAWLSVSACTGSPGCAHSAADVRADAGAAVDPSIAVHRHFVGCDRACGSPADAQVLVATG 362 Query 356 GGYR 359 GYR Sbjct 363 DGYR 366 >gi|145223693|ref|YP_001134371.1| precorrin-3B synthase [Mycobacterium gilvum PYR-GCK] gi|145216179|gb|ABP45583.1| precorrin-3B synthase [Mycobacterium gilvum PYR-GCK] Length=372 Score = 429 bits (1103), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 237/364 (66%), Positives = 272/364 (75%), Gaps = 11/364 (3%) Query 5 RDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQL 64 R+ DACPGAL+ H+AADG L+RIRLPGG IT QL +A A D ++TLELT+RGN+Q+ Sbjct 5 REKDACPGALQTHRAADGDLSRIRLPGGAITPPQLEVVAQAAIDLAASTLELTSRGNLQI 64 Query 65 RGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 RG+RD AAVAD +A AGLLPSATHERVRNIVASPLSGR GGL DVRA V +LDAA++ +P Sbjct 65 RGVRDTAAVADLLAGAGLLPSATHERVRNIVASPLSGRHGGLCDVRALVADLDAAVQRDP 124 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVA--DVAETLI 181 LAEL GRF FG DDGR D+SGLGAD GV D LLL GRDTGVRVA + L+ Sbjct 125 VLAELPGRFLFGFDDGRGDISGLGADAGVHALDDSTAALLLAGRDTGVRVALSSAVDELL 184 Query 182 EVALRFVKIRETAWRVTELADIGELQSGVELGPSVRP------VTKTPVGWIPQDDSRVT 235 VA RFV R WRV EL D L G P+ RP T+ PVGWI Q D R+ Sbjct 185 AVARRFVDGRGKHWRVGELDDPAILLDG--RAPTERPGGTWQARTRPPVGWIEQTDGRIA 242 Query 236 LGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDEN 295 LGAAVPLGVL A+VA LAA+EAPL +TPWRSVLI DLD+ AD ALRVLAPLGL+FDE+ Sbjct 243 LGAAVPLGVLDAQVARYLAAVEAPLTVTPWRSVLIFDLDEGVADVALRVLAPLGLIFDED 302 Query 296 SPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATG 355 S WL++SACTGSPGCAHSAADVRADA +++ A HRHFVGC+RACGSP +VLVATG Sbjct 303 SAWLSVSACTGSPGCAHSAADVRADAGAAVDPSIAVHRHFVGCDRACGSPADAQVLVATG 362 Query 356 GGYR 359 GYR Sbjct 363 DGYR 366 >gi|108799456|ref|YP_639653.1| precorrin-3B synthase [Mycobacterium sp. MCS] gi|119868569|ref|YP_938521.1| precorrin-3B synthase [Mycobacterium sp. KMS] gi|126435110|ref|YP_001070801.1| precorrin-3B synthase [Mycobacterium sp. JLS] gi|108769875|gb|ABG08597.1| Precorrin-3B synthase [Mycobacterium sp. MCS] gi|119694658|gb|ABL91731.1| precorrin-3B synthase [Mycobacterium sp. KMS] gi|126234910|gb|ABN98310.1| precorrin-3B synthase [Mycobacterium sp. JLS] Length=373 Score = 427 bits (1097), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 255/369 (70%), Positives = 290/369 (79%), Gaps = 10/369 (2%) Query 4 TRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQ 63 +RD DACPGAL H+AADGALAR+RLPGGM++ A L LA A+ FGS LELT+RGN+Q Sbjct 5 SRDQDACPGALSVHRAADGALARVRLPGGMLSGAALTALAQAATRFGSPDLELTSRGNLQ 64 Query 64 LRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAE 123 +RGI D AVADAVA AGLLPS THERVRNIVASPLSGR+GGLAD+R V +LDAAIR E Sbjct 65 IRGITDTGAVADAVAAAGLLPSPTHERVRNIVASPLSGRSGGLADLRPLVLDLDAAIRRE 124 Query 124 PRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR--LLLTGRDTGVRVA--DVAET 179 P LAE GRFWFGLDDGR D+SGLG DVGV DG LLL GRDTGVR++ D T Sbjct 125 PVLAESSGRFWFGLDDGRGDISGLGTDVGVHAL-DGELAALLLAGRDTGVRLSLDDAVRT 183 Query 180 LIEVALRFVKIRETAWRVTELADIGELQSGV----ELGPSVRPVTKTPVGWIPQDDSRVT 235 LIEVA+RFV +R AWRV ELA +L +GV E G + PV + PVGWI QDD RVT Sbjct 184 LIEVAVRFVAVRGNAWRVGELATPQDLLAGVAVTAEPGATWPPVVRPPVGWIAQDDGRVT 243 Query 236 LGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDEN 295 LGA +PLGVLPAR AE + A+EAP+VITPWRS+LICDLD+ AD ALRVLAP+GLVFDEN Sbjct 244 LGAGIPLGVLPARTAEFVGAVEAPVVITPWRSLLICDLDEGVADVALRVLAPMGLVFDEN 303 Query 296 SPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATG 355 SPWL++SACTGSPGC SAADVRADAA +++ + GHRHFVGCERACGSPP GEVL+A Sbjct 304 SPWLDVSACTGSPGCERSAADVRADAAAAVDAPAPGHRHFVGCERACGSPPVGEVLIAGP 363 Query 356 GGYR-RLRP 363 GYR R RP Sbjct 364 DGYRPRRRP 372 >gi|118467354|ref|YP_888162.1| precorrin-3B synthase [Mycobacterium smegmatis str. MC2 155] gi|118168641|gb|ABK69537.1| precorrin-3B synthase [Mycobacterium smegmatis str. MC2 155] Length=372 Score = 422 bits (1085), Expect = 4e-116, Method: Compositional matrix adjust. Identities = 247/363 (69%), Positives = 274/363 (76%), Gaps = 7/363 (1%) Query 4 TRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQ 63 TRD DACPGAL HQAADGAL RIRL GG ITAAQLATLA VA+D GS +ELT+RGN+Q Sbjct 4 TRDQDACPGALTVHQAADGALVRIRLAGGAITAAQLATLADVANDLGSPAMELTSRGNIQ 63 Query 64 LRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAE 123 +RG+ D A A A+A AGLLPS THERVRNIVASPL+GR+GG+ADV A V ELDAAI+AE Sbjct 64 IRGLTDTDAAAAALAGAGLLPSPTHERVRNIVASPLTGRSGGVADVGALVSELDAAIQAE 123 Query 124 PRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRV--ADVAETL 180 P LA L GRF FGLDDGR D+SGLG D GV + G LLL G DTGVR+ A V TL Sbjct 124 PELAGLPGRFLFGLDDGRGDISGLGPDAGVHMLDAGTGALLLGGCDTGVRIDRAGVVPTL 183 Query 181 IEVALRFVKIRETAWRVTELADIGELQSGVEL----GPSVRPVTKTPVGWIPQDDSRVTL 236 I VA RF K+ AWRV EL D+ L G+ G P + PVGWIPQ D RV L Sbjct 184 ITVARRFAKVHGKAWRVGELDDLAPLLEGLTATGAGGQRWAPTVRPPVGWIPQRDGRVAL 243 Query 237 GAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENS 296 GA VPLGVL AR A+ LAAIEAP+VITPWRSVL+ DLD+ AD ALRVLAP+GLVFDENS Sbjct 244 GAGVPLGVLSARDAQFLAAIEAPIVITPWRSVLVFDLDEGVADTALRVLAPMGLVFDENS 303 Query 297 PWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGG 356 PWL++SACTGSPGCA S DVRADAA + SA HRHFVGCERACGSPP G+VLVAT Sbjct 304 PWLDVSACTGSPGCAKSLTDVRADAAAAAQEPSANHRHFVGCERACGSPPVGDVLVATED 363 Query 357 GYR 359 GYR Sbjct 364 GYR 366 >gi|120404401|ref|YP_954230.1| precorrin-3B synthase [Mycobacterium vanbaalenii PYR-1] gi|119957219|gb|ABM14224.1| precorrin-3B synthase [Mycobacterium vanbaalenii PYR-1] Length=372 Score = 416 bits (1068), Expect = 4e-114, Method: Compositional matrix adjust. Identities = 236/367 (65%), Positives = 275/367 (75%), Gaps = 9/367 (2%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +A RD DACPGAL+ H+AADG LARIRLPGG ITA QL +A A +FG+ATLELT+R Sbjct 1 MARARDDDACPGALQTHRAADGDLARIRLPGGAITARQLEAVAQAAVNFGTATLELTSRA 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 N+Q+RGI D AVA + AGLLPSATHERVRNIVASPLSGR+GG D R V LD A+ Sbjct 61 NLQIRGIHDTGAVAALLTDAGLLPSATHERVRNIVASPLSGRSGGFCDARDLVRSLDHAV 120 Query 121 RAEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR--LLLTGRDTGVRV--ADV 176 + +PRLA L GRF FG+DDGR D+SGLGAD G+ V DG LLL GRDTGVR+ V Sbjct 121 QQDPRLARLPGRFLFGIDDGRGDISGLGADAGIHVL-DGHTAALLLAGRDTGVRLPLGHV 179 Query 177 AETLIEVALRFVKIRETAWRVTELAD----IGELQSGVELGPSVRPVTKTPVGWIPQDDS 232 + L+ VA RF+++R TAWRV EL D +G+ E G + ++ PVGWI QDD Sbjct 180 VDELLSVAARFLQVRGTAWRVDELDDPTTLLGDRTPTAEPGATWPAHSRPPVGWIEQDDG 239 Query 233 RVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVF 292 R+ LGAAVPLGVL A+VA LAA+EAPL +TPWRSVL+ DLD+ AD ALRVLAPLGLVF Sbjct 240 RIALGAAVPLGVLDAQVARYLAAVEAPLAVTPWRSVLLFDLDEGVADVALRVLAPLGLVF 299 Query 293 DENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLV 352 DENSPWL++SACTGSPGC S ADVRADAA +++ HRHFVGCERACGSP GEVLV Sbjct 300 DENSPWLSVSACTGSPGCERSVADVRADAAAAVDDPVTVHRHFVGCERACGSPADGEVLV 359 Query 353 ATGGGYR 359 ATG GYR Sbjct 360 ATGDGYR 366 >gi|289443568|ref|ZP_06433312.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T46] gi|289416487|gb|EFD13727.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T46] Length=184 Score = 365 bits (938), Expect = 5e-99, Method: Compositional matrix adjust. Identities = 183/184 (99%), Positives = 184/184 (100%), Gaps = 0/184 (0%) Query 180 LIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAA 239 +IEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAA Sbjct 1 MIEVALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAA 60 Query 240 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL 299 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL Sbjct 61 VPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWL 120 Query 300 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR 359 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR Sbjct 121 NISACTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEVLVATGGGYR 180 Query 360 RLRP 363 RLRP Sbjct 181 RLRP 184 >gi|111017194|ref|YP_700166.1| ferredoxin--nitrite reductase [Rhodococcus jostii RHA1] gi|110816724|gb|ABG92008.1| probable ferredoxin--nitrite reductase [Rhodococcus jostii RHA1] Length=377 Score = 359 bits (922), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 194/370 (53%), Positives = 255/370 (69%), Gaps = 15/370 (4%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGAL+ HQAADGALAR+RLPGG++T+ QL TLA A D G+ +ELT+RGN QLR + Sbjct 9 DACPGALQVHQAADGALARVRLPGGVLTSTQLQTLAESARDLGNGEIELTSRGNAQLRAV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 RD A +A AGLLPS THERVRNI+ SPL+GR GGLAD+R V ELD + A+ LA Sbjct 69 RDPQEFARRLADAGLLPSETHERVRNILVSPLTGRIGGLADLRDLVDELDRTLCADSALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRV--ADVAETLIEVA 184 +L GR F LDDGR DVS LG D GV + L+L GRD+G R+ + + L++ A Sbjct 129 DLPGRTLFTLDDGRGDVSALGGDFGVHAVSETEVALVLAGRDSGARITTTESVKVLLDAA 188 Query 185 LRFVKIRETAWRVTELAD-IGELQSGVELGPSVRPVT-----KTPVGWIPQDDSRVTLGA 238 F+++R+ WR++E+AD + S + L P+ PV + P+GW+ Q D VTLG Sbjct 189 RVFLELRDQHWRLSEIADGVERTLSALTLAPTADPVYGFDEHRPPIGWLDQPDGNVTLGG 248 Query 239 AVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPW 298 + G+L AR+AE LAA+E P+++TPW+SVL+CDLD+ +A+ +RVLAP+GL+FDENSPW Sbjct 249 GLAFGILDARLAEFLAAVEKPVIVTPWKSVLLCDLDEWSAEQVVRVLAPMGLIFDENSPW 308 Query 299 LNISACTGSPGCAHSAADVRADAARSL---NVESAGHRHFVGCERACGSPPAGEV--LVA 353 LN+SACTG PGC + ADVR+DA ++ + G +H+ GCER CG P GEV +VA Sbjct 309 LNVSACTGQPGCEKALADVRSDARDAVARGELPVEGRQHWSGCERCCGR-PKGEVADVVA 367 Query 354 TGGGYRRLRP 363 T GYR P Sbjct 368 TETGYRVEEP 377 >gi|226359706|ref|YP_002777484.1| precorrin-3B synthase [Rhodococcus opacus B4] gi|226238191|dbj|BAH48539.1| putative precorrin-3B synthase [Rhodococcus opacus B4] Length=377 Score = 358 bits (919), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 195/366 (54%), Positives = 253/366 (70%), Gaps = 15/366 (4%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGAL+ HQAADGALAR+RLPGG++T+ QL TLA A D G+ +ELT+RGN QLR + Sbjct 9 DACPGALQVHQAADGALARVRLPGGVLTSTQLQTLAESARDLGNGEIELTSRGNAQLRAV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 RD A +A AGLLPS THERVRNI+ SPL+GR GGL D+R VG LD ++ + LA Sbjct 69 RDPLEFARRLAGAGLLPSETHERVRNILVSPLTGRIGGLTDLRDLVGVLDRSLCGDAALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRV--ADVAETLIEVA 184 +L GR F LDDGR DVS LG D GV + L+L GRD+GVR+ +D A L+ A Sbjct 129 DLPGRTLFTLDDGRGDVSALGGDFGVHAVSESEVALILAGRDSGVRIPTSDSAHVLVGAA 188 Query 185 LRFVKIRETAWRVTELAD-IGELQSGVELGPSVRPV-----TKTPVGWIPQDDSRVTLGA 238 F+++R+ WR++E+AD + S + L P+ PV + P+GW+ Q D VTLG Sbjct 189 RAFLELRDRHWRLSEIADGVERTLSALTLAPTADPVRGFDEHRPPIGWLDQPDGNVTLGG 248 Query 239 AVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPW 298 + GVL AR+AE LAA+E P+++TPW+SVL+CDLD+ +A+ +RVLAP+GL+FDENSPW Sbjct 249 GLAFGVLDARLAEFLAAVEKPVIVTPWKSVLLCDLDEWSAEQVVRVLAPMGLIFDENSPW 308 Query 299 LNISACTGSPGCAHSAADVRADAARSL---NVESAGHRHFVGCERACGSPPAGEV--LVA 353 LN+SACTG PGC + ADVR DA ++ + G +H+ GCER CG P GEV +VA Sbjct 309 LNVSACTGQPGCEKALADVRTDARDAVASGELPVEGRQHWSGCERCCGR-PKGEVTDVVA 367 Query 354 TGGGYR 359 T GYR Sbjct 368 TETGYR 373 >gi|305407946|dbj|BAJ15903.1| ferredoxin-nitrite reductase [Rhodococcus opacus] Length=377 Score = 357 bits (917), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 193/370 (53%), Positives = 257/370 (70%), Gaps = 15/370 (4%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGAL+ H+AADGALAR+RLPGG++T+ QL TLA A D G+ +ELT+RGN QLR + Sbjct 9 DACPGALQVHRAADGALARVRLPGGVLTSTQLQTLAESARDLGNGEIELTSRGNAQLRAV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 RD A +A AGLLPS THERVRNI+ SPL+GR GG+AD+R V ELD + A+ LA Sbjct 69 RDPQEFARRLADAGLLPSETHERVRNILVSPLTGRIGGVADLRDLVDELDRTLCADAALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVA--DVAETLIEVA 184 +L GR F LDDGR DVS LG D GV + L+L GRD+G R+A + L++ A Sbjct 129 DLPGRTLFTLDDGRGDVSALGGDFGVHAVSETEVALVLAGRDSGARIAATESVAVLLDAA 188 Query 185 LRFVKIRETAWRVTELAD-IGELQSGVELGPSVRPVT-----KTPVGWIPQDDSRVTLGA 238 F+++R+ WR++E+AD + + S + L P+ PV+ + P+GW+ Q D VTLG Sbjct 189 RVFLELRDQHWRLSEIADGVERVLSALTLAPTADPVSGFDDHRPPIGWLDQPDGNVTLGG 248 Query 239 AVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPW 298 + G+L AR+AE LAA+E P+++TPW+SVL+CDLD+ +A+ +RVLAP+GL+FDENSPW Sbjct 249 GLAFGILDARLAEFLAAVEKPVIVTPWKSVLLCDLDEWSAEQVVRVLAPMGLIFDENSPW 308 Query 299 LNISACTGSPGCAHSAADVRADAARSL---NVESAGHRHFVGCERACGSPPAGEV--LVA 353 LN+SACTG PGC + ADVR+DA ++ + G +H+ GCER CG P GEV +VA Sbjct 309 LNVSACTGQPGCEKALADVRSDARNAVASGELPVEGRQHWSGCERCCGR-PKGEVADVVA 367 Query 354 TGGGYRRLRP 363 T GYR P Sbjct 368 TETGYRVEEP 377 >gi|169629286|ref|YP_001702935.1| cobalamin biosynthesis protein CobG [Mycobacterium abscessus ATCC 19977] gi|169241253|emb|CAM62281.1| Probable cobalamin biosynthesis protein CobG [Mycobacterium abscessus] Length=386 Score = 345 bits (885), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 214/375 (58%), Positives = 249/375 (67%), Gaps = 21/375 (5%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGALR H+AADGALARIRLPGGM+++AQLA LA A D G+ LELT+RGNVQLR + Sbjct 8 DACPGALRLHEAADGALARIRLPGGMLSSAQLAALAEAAGDHGAPILELTSRGNVQLRSV 67 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 RD AV +++AGLLPS HERVRNIVASPLSGRAG D R V LD + A LA Sbjct 68 RDANAVGALLSEAGLLPSPRHERVRNIVASPLSGRAGEFPDARPLVSALDRGLTAAATLA 127 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGV---RVADVAETLIEVA 184 EL GRF F LDDGR D++ +GAD+G++ G RLLL GR T V D E ++ A Sbjct 128 ELPGRFLFSLDDGRGDMAAMGADIGLRHDQKGWRLLLGGRTTSVCDGDAVDAVERMLTAA 187 Query 185 LRFVKIRETAWRVTELAD-IGELQSGVEL-----GPSVRPVTKTPVGWIPQ------DDS 232 +FV+IR AWRV EL + G L ++ P P + PVGWI Q Sbjct 188 RKFVEIRGNAWRVAELPEGAGTLARAIDAVFIDGPPDPTPAPRAPVGWIEQLRTGESPGE 247 Query 233 RVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVF 292 VTLGAAVPLG LPARVA LAA+E P+++TPWRSVL+CDL ADA LRVLAPLGLVF Sbjct 248 LVTLGAAVPLGQLPARVAALLAAVEKPVIVTPWRSVLLCDLPHGDADAVLRVLAPLGLVF 307 Query 293 DENSPWLNISACTGSPGCAHSAADVRADAARSL------NVESAGHRHFVGCERACGSPP 346 DE SPWLN S+CTG PGC S DV AD + + S HRH+VGC RACGSP Sbjct 308 DERSPWLNASSCTGLPGCGRSRTDVHADVRLEVAEEIASGIHSPVHRHWVGCPRACGSPS 367 Query 347 AGEVLVATGGGYRRL 361 G+VLVAT GYR L Sbjct 368 TGQVLVATELGYRPL 382 >gi|325676798|ref|ZP_08156471.1| cobalamin biosynthesis protein [Rhodococcus equi ATCC 33707] gi|325552346|gb|EGD22035.1| cobalamin biosynthesis protein [Rhodococcus equi ATCC 33707] Length=379 Score = 331 bits (848), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 188/370 (51%), Positives = 242/370 (66%), Gaps = 15/370 (4%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 D CPGA + HQAADG LAR+RLPGG+IT+ QL LA+ A + G+ +ELT+RGNVQLR + Sbjct 9 DKCPGAFQVHQAADGPLARVRLPGGVITSPQLQALATAAHEIGNGEIELTSRGNVQLRAV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 D A +A GLLPS THERVRNI+ASPLSGR GG ADVR V +LD + A+P LA Sbjct 69 SDPEEFARRIADVGLLPSTTHERVRNILASPLSGRIGGFADVRGLVTDLDRGLCADPALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR-LLLTGRDTGVRV--ADVAETLIEVA 184 EL GR F LDDG D+SGL D GV DG L+L G DTG R+ AD + L+ A Sbjct 129 ELPGRTLFTLDDGTGDISGLRGDFGVHALDDGRFALVLAGTDTGARLAEADAVDVLLASA 188 Query 185 LRFVKIRETAWRVTELADIGEL---QSGVELGPSVR---PVTKTPVGWIPQDDSRVTLGA 238 F +IR AWR+ E+ E + G+ G V+ + + P+GW+ Q D V L A Sbjct 189 RTFAEIRGDAWRLNEVPGGTERVLGRLGLAYGDPVQFPGAIDRGPIGWLDQPDGNVALAA 248 Query 239 AVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPW 298 + G LPAR+AE LAA+E P+++TPWRS+++ DL++ A+ +RVLAP+GL+FDENSP+ Sbjct 249 GLAFGTLPARLAEFLAAVEKPIIVTPWRSIVLPDLEEWAAEQVVRVLAPMGLIFDENSPY 308 Query 299 LNISACTGSPGCAHSAADVRAD---AARSLNVESAGHRHFVGCERACGSPPAGEV--LVA 353 L +SAC G PGCA S DVRAD A S ++ + G +H+ GC+R CG P GEV +VA Sbjct 309 LQVSACAGQPGCAKSHTDVRADARAAIESGDLPADGRQHWSGCDRKCGR-PRGEVTDVVA 367 Query 354 TGGGYRRLRP 363 GYR P Sbjct 368 DPDGYRVENP 377 >gi|312139750|ref|YP_004007086.1| precorrin-3b synthase cobg [Rhodococcus equi 103S] gi|311889089|emb|CBH48402.1| putative precorrin-3B synthase CobG [Rhodococcus equi 103S] Length=379 Score = 329 bits (844), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 188/370 (51%), Positives = 242/370 (66%), Gaps = 15/370 (4%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 D CPGAL+ HQAADG LAR+RLPGG+IT+ QL LA+ A + G+ +ELT+RGNVQLR + Sbjct 9 DKCPGALQVHQAADGPLARVRLPGGVITSPQLQALATAAHEIGNGEIELTSRGNVQLRAV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 D A +A GLLPS THERVRNI+ASPLSGR GG ADVR V +LD + A+P LA Sbjct 69 SDPEEFARRIADVGLLPSTTHERVRNILASPLSGRIGGFADVRGLVTDLDRGLCADPALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR-LLLTGRDTGVRV--ADVAETLIEVA 184 EL GR F LDDG D+SGL D GV DG L+L G DTG R+ AD + L+ A Sbjct 129 ELPGRTLFTLDDGTGDISGLRGDFGVHALDDGRFALVLAGTDTGARLAEADAVDVLLASA 188 Query 185 LRFVKIRETAWRVTELADIGEL---QSGVELGPSVR---PVTKTPVGWIPQDDSRVTLGA 238 F +IR AWR+ E+ E + G+ G V+ + + P+GW+ Q D V L A Sbjct 189 RTFAEIRGDAWRLNEVPGGTERVLGRLGLAYGDPVQFPGAIDRGPIGWLDQPDGNVALAA 248 Query 239 AVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPW 298 + G LPAR+AE LAA+E P+++TPWRS+++ DL++ A+ +RVLAP+GL+FDE SP+ Sbjct 249 GLAFGTLPARLAEFLAAVEKPIIVTPWRSIVLPDLEEWAAEQVVRVLAPMGLIFDETSPY 308 Query 299 LNISACTGSPGCAHSAADVRAD---AARSLNVESAGHRHFVGCERACGSPPAGEV--LVA 353 L +SAC G PGCA S DVRAD A S ++ + G +H+ GC+R CG P GEV +VA Sbjct 309 LQVSACAGQPGCAKSHTDVRADARAAIESGDLPADGRQHWSGCDRKCGR-PRGEVTDVVA 367 Query 354 TGGGYRRLRP 363 GYR P Sbjct 368 DPDGYRVENP 377 >gi|229493617|ref|ZP_04387402.1| precorrin-3B synthase [Rhodococcus erythropolis SK121] gi|229319578|gb|EEN85414.1| precorrin-3B synthase [Rhodococcus erythropolis SK121] Length=380 Score = 328 bits (842), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 191/371 (52%), Positives = 245/371 (67%), Gaps = 24/371 (6%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGAL+ H AADGALAR+RLPGG++T QL TLA A D G+ +ELT+RGNVQLR + Sbjct 9 DACPGALQVHHAADGALARVRLPGGLLTPTQLQTLADAARDLGNGQMELTSRGNVQLRSV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 D A A +A AGLLPSATHERVRNI+ASPLSGR GG+ D+R V LD+AI+A+ LA Sbjct 69 SDPEAFAARIASAGLLPSATHERVRNILASPLSGRIGGVTDIRELVHRLDSAIQADQALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR-LLLTGRDTG--VRVADVAETLIEVA 184 +L GR F LDDGR D++GL D G+ L+L G T V+ D E L+E A Sbjct 129 DLPGRTLFTLDDGRGDITGLRGDFGLHARSATEHSLVLAGHHTTHLVQADDAVELLLEAA 188 Query 185 LRFVKIRETAWRVTE--------LADIG---ELQSGVELGPSVRPVTKTPVGWIPQDDSR 233 F+ +R+ WR+ E LA +G E +L P RP +GW+ Q D Sbjct 189 RSFLDVRDKHWRLAEVPDGIERTLAQLGLSAESTVATDLTPDARPT----IGWLEQRDGT 244 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V LG + G+L AR+AE LAA++ P+V+TPWRSV I DLD+ A+ +RVLAP+GL+FD Sbjct 245 VALGGGLRFGLLDARLAEFLAAVDKPVVVTPWRSVHIFDLDEWAAEQVVRVLAPMGLIFD 304 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSL---NVESAGHRHFVGCERACGSPPAGEV 350 ENSPWL ++ACTGSPGC S ADVRADA ++ + G +H+ GC+R+CG P G+V Sbjct 305 ENSPWLEVTACTGSPGCEKSLADVRADAITAVEQAELPVVGRQHWAGCDRSCGR-PRGDV 363 Query 351 --LVATGGGYR 359 ++ATG GYR Sbjct 364 ADVIATGDGYR 374 >gi|333919709|ref|YP_004493290.1| ferredoxin-nitrite reductase [Amycolicicoccus subflavus DQS3-9A1] gi|333481930|gb|AEF40490.1| Ferredoxin-nitrite reductase [Amycolicicoccus subflavus DQS3-9A1] Length=392 Score = 328 bits (840), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 191/371 (52%), Positives = 254/371 (69%), Gaps = 15/371 (4%) Query 4 TRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQ 63 ++ D CPGALR H+AADG LAR+RLPGG +T+ Q+ TLA ++ + G+ LELT+RGN+Q Sbjct 19 SKPEDRCPGALRLHEAADGLLARVRLPGGALTSEQMQTLAMISREHGNDILELTSRGNIQ 78 Query 64 LRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAE 123 +RGIRD VA +A AGLLPSATHERVRNI++SPLSG GG ADVR WV +LD A+R + Sbjct 79 IRGIRDGTTVAALLADAGLLPSATHERVRNILSSPLSGLIGGFADVRTWVSDLDVALRGD 138 Query 124 PRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVA--DVAETL 180 LA+L GRF +DDGR DV+ L D+ V+ + LLL G+DTG+RV + L Sbjct 139 EVLADLPGRFLMAIDDGRGDVAALDPDIAAMVYDESSVALLLAGQDTGIRVTPDETVPLL 198 Query 181 IEVALRFVKIRETAWRVTELADIGEL---QSGVELGPSVRPVTKT-----PVGWIPQDDS 232 I + F+ +R + WRV EL G G+ P PV + P+GWI Q+D Sbjct 199 IRTSRAFLTVRSSEWRVKELPRGGNEIVDHLGLSADPDHSPVAISSRPLPPIGWITQEDD 258 Query 233 RVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVF 292 R+ LGA + LG L +R+ E LAAIE LVITPWR+++I DLD+ A+ +RVLAP+GL+F Sbjct 259 RIALGAGLKLGRLDSRLGEFLAAIERGLVITPWRTLVISDLDEWRAEQVVRVLAPMGLIF 318 Query 293 DENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA---GHRHFVGCERACGSPPAG- 348 D SPW+++SACTGSPGC+ + ADV+ADAA ++ S+ G +H+VGCERACG+PP Sbjct 319 DAESPWIDVSACTGSPGCSKAVADVQADAAHAVGTGSSPVEGKQHWVGCERACGTPPGDI 378 Query 349 EVLVATGGGYR 359 V+VAT GY+ Sbjct 379 SVVVATPDGYQ 389 >gi|226306629|ref|YP_002766589.1| precorrin-3B synthase [Rhodococcus erythropolis PR4] gi|226185746|dbj|BAH33850.1| precorrin-3B synthase [Rhodococcus erythropolis PR4] Length=380 Score = 325 bits (834), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 188/371 (51%), Positives = 243/371 (66%), Gaps = 24/371 (6%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 DACPGAL+ H AADGALAR+RLPGG++T QL TLA A D G+ +ELT+RGNVQLR + Sbjct 9 DACPGALQVHHAADGALARVRLPGGLLTPVQLQTLADAARDLGNGQMELTSRGNVQLRSV 68 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLA 127 D A A +A AGLLPSATHERVRNI+ASPLSGR GG+AD+R V LD+AI+A+ LA Sbjct 69 SDPEAFAARIASAGLLPSATHERVRNILASPLSGRIGGVADIRELVHRLDSAIQADQALA 128 Query 128 ELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPR-LLLTGRDTG--VRVADVAETLIEVA 184 +L GR F LDDGR D++GL D G+ L+L G T V+ D E L+ A Sbjct 129 DLPGRTLFTLDDGRGDITGLRGDFGLHARSATEHSLVLAGHHTTHLVQADDAVELLLAAA 188 Query 185 LRFVKIRETAWRVTELAD-----------IGELQSGVELGPSVRPVTKTPVGWIPQDDSR 233 F+ +R+ WR+ E+ D E +L P RP +GW+ Q D Sbjct 189 RSFLDVRDKHWRLAEVPDGIERTLEQLGLSAESTGAADLTPDARPT----IGWLEQRDGT 244 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V LG + G+L AR+AE LAA++ P+V+TPWRSV I DLD+ A+ +RVLAP+GL+FD Sbjct 245 VALGGGLRFGLLDARLAEFLAAVDKPVVVTPWRSVHIFDLDEWAAEQVVRVLAPMGLIFD 304 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSL---NVESAGHRHFVGCERACGSPPAGEV 350 ENSPWL+++ACTGSPGC S ADVR DA ++ + G +H+ GC+R+CG P G+V Sbjct 305 ENSPWLDVTACTGSPGCEKSLADVRTDAITAVEQAELPVVGRQHWAGCDRSCGR-PRGDV 363 Query 351 --LVATGGGYR 359 ++ATG GYR Sbjct 364 ADVIATGDGYR 374 >gi|54025109|ref|YP_119351.1| hypothetical protein nfa31400 [Nocardia farcinica IFM 10152] gi|54016617|dbj|BAD57987.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=394 Score = 305 bits (781), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 192/390 (50%), Positives = 237/390 (61%), Gaps = 37/390 (9%) Query 4 TRDA-DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNV 62 TR A DACPG LR HQAADG LAR+R+PGG++T QL LA A++ G LELT+RGNV Sbjct 2 TRTAPDACPGVLRLHQAADGPLARVRIPGGLLTPDQLRGLAEAATELGDGALELTSRGNV 61 Query 63 QLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRA 122 QLR +RD A + + AGLLPS +HERVRNIVASPL+GR GG V V LDA + A Sbjct 62 QLRRVRDAAELTARLEAAGLLPSHSHERVRNIVASPLAGRTGGTGAVHPLVAALDARLLA 121 Query 123 EPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAETL 180 +P LA L GR F LDDGR +S LG D+GVQ D LLL G DTG+R+A D + + Sbjct 122 DPALASLPGRVLFTLDDGRGAISALGGDIGVQAVTDEFALLLAGADTGIRLAATDAVDVM 181 Query 181 IEVALRFVKIRETAWRVTELAD-IGELQSGVELGPSVRPV-----TKTPVGWIPQDDSRV 234 I A F+ + WR+ E+ D + + L P+ V P+GW+PQDD V Sbjct 182 IAAAHAFLALSSGQWRLHEIPDGAARVVDLLGLSPTDNRVEPAPPAAPPIGWLPQDDGLV 241 Query 235 TLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDE 294 LGA V LG LPAR AE L A+E P+V+TPWR +++ DLD+ TA+ +RVLAP+GL+FD Sbjct 242 ALGAGVALGSLPARTAEFLVAVERPVVLTPWRGLVVTDLDEWTAEQVVRVLAPMGLIFDA 301 Query 295 NSPWLNISACTGSPGCAHSAADVRAD------------------------AARSLNVESA 330 NSPWL +SAC G PGCA S DVRAD AA L V A Sbjct 302 NSPWLLVSACAGRPGCAKSHTDVRADVAAAVAEGRVPGPGEPTTLAAGPRAADQLAV--A 359 Query 331 GHRHFVGCERACGSP--PAGEVLVATGGGY 358 G +H+ GC+R CG P P EV A G + Sbjct 360 GRQHWSGCDRRCGRPRGPVVEVTAAADGYH 389 >gi|254819623|ref|ZP_05224624.1| CobG [Mycobacterium intracellulare ATCC 13950] Length=214 Score = 290 bits (741), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 159/209 (77%), Positives = 175/209 (84%), Gaps = 3/209 (1%) Query 157 PDGPRLLLTGRDTGVRVA--DVAETLIEVALRFVKIRETAWRVTELADIGELQSGVELGP 214 PDG LLL GRDTGVR+A +V ETL+ +A RFV+IRETAWRV ELAD+ L E G Sbjct 5 PDGCALLLDGRDTGVRLAAGEVVETLVALATRFVEIRETAWRVQELADLRRLLPDAEPGG 64 Query 215 SVRPV-TKTPVGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDL 273 + PV TK PVGWI QDD RVTLGAAVPLGVLPARVAE LAAIEAPLVITPWRSVL+CDL Sbjct 65 TPFPVVTKAPVGWIGQDDGRVTLGAAVPLGVLPARVAEYLAAIEAPLVITPWRSVLVCDL 124 Query 274 DDATADAALRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHR 333 ++ AD ALRVLAPLGLVFDENSPWL +SACTGSPGCAHSAADVRADAA++L+ + HR Sbjct 125 QESVADTALRVLAPLGLVFDENSPWLTVSACTGSPGCAHSAADVRADAAQALDADVTQHR 184 Query 334 HFVGCERACGSPPAGEVLVATGGGYRRLR 362 HFVGCERACGSPPAG+VLVATG GYR LR Sbjct 185 HFVGCERACGSPPAGQVLVATGDGYRMLR 213 >gi|262202407|ref|YP_003273615.1| precorrin-3B synthase [Gordonia bronchialis DSM 43247] gi|262085754|gb|ACY21722.1| precorrin-3B synthase [Gordonia bronchialis DSM 43247] Length=378 Score = 286 bits (733), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 182/367 (50%), Positives = 226/367 (62%), Gaps = 28/367 (7%) Query 17 HQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGIRDVAAVADA 76 H AADG LARIRLPGG IT QLA LA A++FG LELTAR N+QLRGI DV AVA+ Sbjct 5 HAAADGHLARIRLPGGEITGPQLAHLARAAAEFGDGHLELTARANIQLRGITDVDAVAEI 64 Query 77 VAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRLAELGGRFWFG 136 V +AGL+PSATHE+VRNI A PLSGR GG+ DVRA + LD A+RA+ RLA L GRF FG Sbjct 65 VLEAGLVPSATHEKVRNIAAGPLSGRIGGIGDVRALIAPLDEALRADDRLASLSGRFLFG 124 Query 137 LDDGRADVSGLGADVGV---QVFPDGP--RLLLTGRDTGVRVAD--VAETLIEVALRFVK 189 LDDGR D+ DV GP +++ G G V V ++ VA F Sbjct 125 LDDGRGDILRRDPDVCAVARMTTERGPAVDIVVAGETWGSAVGTDAVVAAMLGVAREFAA 184 Query 190 IRETAWRVTE-----LADIGE---------LQSGVELGPSVRPVTKTPVGWIPQDDSRVT 235 + TAWR+++ LA +GE ++ ++LG + PV VGW QDD V Sbjct 185 VAGTAWRISDLDAETLAGLGERARAGLNEPIRRDLDLGDAAGPV----VGWFDQDDGAVM 240 Query 236 LGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDEN 295 LGA V L +P+R+AE LAAI+ P++ITP R +LICDL +A A+ +RVLAP+GL+FD Sbjct 241 LGAVVELARIPSRLAEFLAAIDTPIIITPDREILICDLSEAVAETVVRVLAPMGLIFDAA 300 Query 296 SPWLNISACTGSPGCAHSAADVRAD-AARSLNVESAGHR-HFVGCERACGSPPAGEVLV- 352 SPW +S C G+PGCA A VR D AR + R H+VGC R CGSP + V Sbjct 301 SPWALVSCCAGAPGCASGLAPVRDDLLARVRDGAPVTVREHWVGCGRGCGSPATQHLRVE 360 Query 353 ATGGGYR 359 A GYR Sbjct 361 AEPDGYR 367 >gi|213965647|ref|ZP_03393841.1| precorrin-3B synthase [Corynebacterium amycolatum SK46] gi|213951806|gb|EEB63194.1| precorrin-3B synthase [Corynebacterium amycolatum SK46] Length=433 Score = 282 bits (722), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 167/377 (45%), Positives = 216/377 (58%), Gaps = 22/377 (5%) Query 3 GTRD-ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGN 61 GTR D CPG + H AADGA+ R+R PGG + A A LA +A +FG + T+RGN Sbjct 49 GTRTRQDGCPGTRKVHIAADGAIGRLRFPGGFLPAPGFAVLADLAENFGDGDIHFTSRGN 108 Query 62 VQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIR 121 VQ+RGI + A ADA + L+PS +H+RVRN++ SPLSGR GG ADVR V E D A+ Sbjct 109 VQIRGITNTGAFADAAEEEKLVPSTSHDRVRNVLQSPLSGRVGGKADVRDLVQEFDKALI 168 Query 122 AEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVA--DVAE 178 AEP LA L GR DDGR DV G D GV + L++ G +G+ V+ DV E Sbjct 169 AEPSLATLPGRTLMAFDDGRGDVLGERPDFGVVAHDESTFELIIGGATSGIVVSRDDVVE 228 Query 179 TLIEVALRFVKIRETAWRVTELADIGELQSGV--ELGPSVRPVTKTP------------- 223 LI A + R +AWR+ E + V ELG VR TP Sbjct 229 ALIATAKVWNDNRGSAWRIAEANAAERVADAVIEELGARVRRQQPTPAENFDATAGLSRQ 288 Query 224 VGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALR 283 +GWI Q D V+L A + GVLPAR+A ++ + P+ ITPW S+++ DL++ A+ ++ Sbjct 289 IGWIDQPDGLVSLAAGLRFGVLPARLARAISHTQVPVHITPWYSLILHDLEEEVAEQVVK 348 Query 284 VLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSL--NVESAGHRHFVGCERA 341 VLAP GL+FD S WL +SACTG PGC S AD R DA+ ++ G HF GCER Sbjct 349 VLAPNGLIFDRKSTWLRVSACTGRPGCEKSLADTRGDASHAIADGRLPEGRVHFSGCERR 408 Query 342 CGSPPAGEV-LVATGGG 357 CG P G +ATG G Sbjct 409 CGKPKGGYFDYLATGDG 425 >gi|337290702|ref|YP_004629723.1| cobalamin biosynthesis protein [Corynebacterium ulcerans BR-AD22] gi|334699008|gb|AEG83804.1| cobalamin biosynthesis protein [Corynebacterium ulcerans BR-AD22] Length=391 Score = 269 bits (688), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 151/367 (42%), Positives = 213/367 (59%), Gaps = 22/367 (5%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 +D CPGAL+ H A DG++ R+R PGG + Q T+A +A + G T+ +T RGN+Q RG Sbjct 24 SDMCPGALKLHHATDGSIGRVRFPGGRVRPEQWKTIAQIARELGDGTIHITTRGNMQFRG 83 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 ++D A A V KAG LPS +H+++RNI+ASPL ++R V LDAA+ + + Sbjct 84 VKDEAQFATVVEKAGFLPSRSHDKIRNILASPLH------PELRPLVESLDAALLNDDVV 137 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVAD---VAETLIEV 183 + L GR FG D G D+ G D GV D ++L G+ T +R+ + E L Sbjct 138 SGLSGRTLFGFDAGEGDILGQRPDFGVIALDDAHHMILGGQITEIRLNTLDIIPEVLTFA 197 Query 184 ALRFVKIRETAWRVTE-------LADIGELQSGVELGPSVRPVTK---TPVGWIPQDDSR 233 A + + RE +WR+ E + D + V+ P PV + PVGWI D R Sbjct 198 ARMWQENREDSWRLHESPSIRAHILDQVQTHFSVDTQPVTPPVIEGSARPVGWIDLGDER 257 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V+LGA + G L A+VA+ L+AI+A ITPW S++I DL ADA ++VLAPLGL+FD Sbjct 258 VSLGAGLRFGFLTAQVADILSAIDAETTITPWASIVIHDLPHHDADAVVKVLAPLGLIFD 317 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAGEV- 350 + SPWL ++ACTG PGC S ++ + DA + + + A G HF GC+R CG P + Sbjct 318 QESPWLRVTACTGLPGCQKSLSNTQKDATQLVLSDKAPEGLVHFSGCDRRCGHPLSHHTE 377 Query 351 LVATGGG 357 VATG G Sbjct 378 YVATGDG 384 >gi|334696815|gb|AEG81612.1| cobalamin biosynthesis protein [Corynebacterium ulcerans 809] Length=391 Score = 268 bits (685), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 150/367 (41%), Positives = 213/367 (59%), Gaps = 22/367 (5%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 +D CPGAL+ H A DG++ R+R PGG + Q T+A +A + G T+ +T RGN+Q RG Sbjct 24 SDMCPGALKLHHATDGSIGRVRFPGGRVRPEQWKTIAQIARELGDGTIHITTRGNMQFRG 83 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 ++D A A V KAG LPS +H+++RNI+ASPL ++R V LDAA+ + + Sbjct 84 VKDEAQFATVVEKAGFLPSRSHDKIRNILASPLH------PELRPLVESLDAALLNDDVV 137 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVAD---VAETLIEV 183 + L GR FG D G D+ G D GV D ++L G+ T +R+ + E L Sbjct 138 SGLSGRTLFGFDAGEGDILGQRPDFGVIALDDAHHMILGGQITEIRLNTLDIIPEVLTFA 197 Query 184 ALRFVKIRETAWRVTE-------LADIGELQSGVELGPSVRPVTK---TPVGWIPQDDSR 233 A + + RE +WR+ E + D + V+ P P+ + PVGWI D R Sbjct 198 ARMWQENREDSWRLHESPSIRAYILDQVQTHFAVDTQPVTPPIIEGSARPVGWIDLGDER 257 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V+LGA + G L A+VA+ L+AI+A ITPW S++I DL ADA ++VLAPLGL+FD Sbjct 258 VSLGAGLRFGFLTAQVADILSAIDAETTITPWASIVIHDLPHHDADAVVKVLAPLGLIFD 317 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAGEV- 350 + SPWL ++ACTG PGC S ++ + DA + + + A G HF GC+R CG P + Sbjct 318 QESPWLRVTACTGLPGCQKSLSNTQKDATQLVLSDKAPEGLVHFSGCDRRCGHPLSHHTE 377 Query 351 LVATGGG 357 VATG G Sbjct 378 YVATGDG 384 >gi|343927919|ref|ZP_08767385.1| precorrin-3B synthase [Gordonia alkanivorans NBRC 16433] gi|343762142|dbj|GAA14311.1| precorrin-3B synthase [Gordonia alkanivorans NBRC 16433] Length=393 Score = 266 bits (680), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 178/388 (46%), Positives = 215/388 (56%), Gaps = 44/388 (11%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 AD CPG H+A DGALARIRLPGG I A QL TLA A+ LELTARGN+QLRG Sbjct 17 ADRCPGVFSTHEAQDGALARIRLPGGRIRADQLTTLAQAAAAHADGFLELTARGNLQLRG 76 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 I DV AVADAV AGL PS++H++VRNI SPL+GR GG+ D LD A+RA+P Sbjct 77 IADVEAVADAVVSAGLAPSSSHDKVRNIEVSPLTGRIGGVIDAGPLTAALDDALRADPAA 136 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADV---------- 176 + GRF FG+DDGR D+ GAD R VAD+ Sbjct 137 TSISGRFLFGVDDGRGDIRRRGADA-----------CAVARSAEPVVADILVGGVAVGSV 185 Query 177 ------AETLIEVALRFVKIRETAWRVTELA--DIGELQSGV--ELGPSVR--------P 218 E LI VA + AWRV +L D L+ V L P+V P Sbjct 186 GGVPGIVEALISVAAGLNAVAPGAWRVRDLGAEDRHRLERLVAENLAPTVESDEDDVAAP 245 Query 219 VTKTPVGWIPQDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATA 278 V VGW QDD V LG+ V LG LPAR+AE + A+E+P+V TP R +LICDL + A Sbjct 246 VEPI-VGWFDQDDGSVLLGSVVELGRLPARLAEFIGAVESPVVFTPDREILICDLGEGVA 304 Query 279 DAALRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRAD--AARSLNVESAGHRHFV 336 + +RVLAP+GL+FD NSPW +S C G+PGC + A VR D A + H+V Sbjct 305 ETVVRVLAPMGLIFDANSPWARLSCCVGAPGCGSANAPVREDLLAHVEAGLPVGDREHWV 364 Query 337 GCERACGSPPAGEVLVAT--GGGYRRLR 362 GCER CGSP + V GGY R R Sbjct 365 GCERRCGSPAGTHLSVQATPDGGYDRRR 392 >gi|302330711|gb|ADL20905.1| Precorrin-3B synthase [Corynebacterium pseudotuberculosis 1002] gi|341824833|gb|AEK92354.1| Precorrin-3B synthase [Corynebacterium pseudotuberculosis PAT10] Length=391 Score = 260 bits (664), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 148/367 (41%), Positives = 210/367 (58%), Gaps = 22/367 (5%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 +D CPGAL+ H A DGA+ R+R PGG + Q T+A +A + G T+ +T RGN+Q RG Sbjct 24 SDMCPGALKLHHATDGAIGRVRFPGGRVRPEQWKTIAQIARELGDGTIHITTRGNMQFRG 83 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 ++D A A V ++G LPS +H+++RNI+ASPL L D LDAA+ + + Sbjct 84 VKDEAQFATVVEESGFLPSRSHDKIRNILASPLHPELWPLVD------SLDAALLNDDVV 137 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVAD---VAETLIEV 183 + L GR FG D G D+ D GV D ++L G+ T +R+ D + + L Sbjct 138 SGLSGRTLFGFDAGEGDILSQRPDFGVIAIDDAHHMILGGQITEIRLNDLEIIPKVLTFA 197 Query 184 ALRFVKIRETAWRVTELADIGEL-------QSGVELGPSVRPVTK---TPVGWIPQDDSR 233 A + + RE +WR+ E + L VE P + PV + PVGWI D R Sbjct 198 ARIWQENREASWRLHESPSVRALILEQIQAHFAVETQPVIPPVIEGSARPVGWIDLGDER 257 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V+LGA + G L A+VA+ L+AI+A ITPW S++I +L ADA ++VLAPLG++FD Sbjct 258 VSLGAGLRFGFLTAQVADILSAIDAETTITPWASIVIHNLPHYDADAVVKVLAPLGMLFD 317 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAGEV- 350 + SPWL ++ACTG PGC S ++ + DA + + A G HF GC+R CG P + Sbjct 318 QESPWLRVTACTGLPGCQKSLSNTQNDATQLVISGKAPEGLVHFSGCDRRCGHPLSHHTE 377 Query 351 LVATGGG 357 VATG G Sbjct 378 YVATGDG 384 >gi|300858441|ref|YP_003783424.1| cobalamin biosynthesis protein [Corynebacterium pseudotuberculosis FRC41] gi|300685895|gb|ADK28817.1| cobalamin biosynthesis protein [Corynebacterium pseudotuberculosis FRC41] gi|302206154|gb|ADL10496.1| Precorrin-3B synthase [Corynebacterium pseudotuberculosis C231] gi|308276394|gb|ADO26293.1| Putative cobalamin biosynthesis protein [Corynebacterium pseudotuberculosis I19] Length=438 Score = 259 bits (663), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 148/367 (41%), Positives = 210/367 (58%), Gaps = 22/367 (5%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 +D CPGAL+ H A DGA+ R+R PGG + Q T+A +A + G T+ +T RGN+Q RG Sbjct 71 SDMCPGALKLHHATDGAIGRVRFPGGRVRPEQWKTIAQIARELGDGTIHITTRGNMQFRG 130 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 ++D A A V ++G LPS +H+++RNI+ASPL L D LDAA+ + + Sbjct 131 VKDEAQFATVVEESGFLPSRSHDKIRNILASPLHPELWPLVD------SLDAALLNDDVV 184 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVAD---VAETLIEV 183 + L GR FG D G D+ D GV D ++L G+ T +R+ D + + L Sbjct 185 SGLSGRTLFGFDAGEGDILSQRPDFGVIAIDDAHHMILGGQITEIRLNDLEIIPKVLTFA 244 Query 184 ALRFVKIRETAWRVTELADIGEL-------QSGVELGPSVRPVTK---TPVGWIPQDDSR 233 A + + RE +WR+ E + L VE P + PV + PVGWI D R Sbjct 245 ARIWQENREASWRLHESPSVRALILEQIQAHFAVETQPVIPPVIEGSARPVGWIDLGDER 304 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 V+LGA + G L A+VA+ L+AI+A ITPW S++I +L ADA ++VLAPLG++FD Sbjct 305 VSLGAGLRFGFLTAQVADILSAIDAETTITPWASIVIHNLPHYDADAVVKVLAPLGMLFD 364 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAGEV- 350 + SPWL ++ACTG PGC S ++ + DA + + A G HF GC+R CG P + Sbjct 365 QESPWLRVTACTGLPGCQKSLSNTQNDATQLVISGKAPEGLVHFSGCDRRCGHPLSHHTE 424 Query 351 LVATGGG 357 VATG G Sbjct 425 YVATGDG 431 >gi|326382301|ref|ZP_08203993.1| precorrin-3B synthase [Gordonia neofelifaecis NRRL B-59395] gi|326199031|gb|EGD56213.1| precorrin-3B synthase [Gordonia neofelifaecis NRRL B-59395] Length=385 Score = 256 bits (655), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 172/376 (46%), Positives = 207/376 (56%), Gaps = 20/376 (5%) Query 4 TRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQ 63 + AD CPG R H AADG LARIRL GG I A L LA+ A +FG +ELT R N+Q Sbjct 2 NKPADRCPGVFRTHPAADGHLARIRLSGGKIEPAALEALAAAAEEFGDGGIELTVRANLQ 61 Query 64 LRGI--RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIR 121 +RGI DVA AD + AGL+ H+RVRNIV S LSGR GG AD+ + V L+ + Sbjct 62 VRGIAADDVAPFADRILAAGLVTDEAHDRVRNIVVSTLSGRVGGRADMWSAVAGLETELL 121 Query 122 AEPRLAELGGRFWFGLDDGRADVSGLGADVGV-QVFPDGPRLLLTGRDTG--VRVADVAE 178 L GRFWFG DDGR DV DV V V D L L G TG V +AD Sbjct 122 RHEWTQALSGRFWFGFDDGRGDVVSREPDVTVVAVGGDEVELHLAGIPTGRVVPLADAPT 181 Query 179 TLIEVALRFVKIRETAWRVTELADIGE--LQSGV----ELGPSVRPVTKTP----VGWIP 228 ++ A F + R WR+ EL G + +G+ G + P P VGW Sbjct 182 AMVRAAAAFHEQRSDEWRINELTSEGRSAIAAGIADLGRRGSACVPDRPDPDGPVVGWFE 241 Query 229 QDDSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPL 288 Q D RV LGA L +R A+ AAI P+++TP R VLI DL + A+ +RVLAPL Sbjct 242 QSDGRVLLGAVTEFARLSSRQAQFAAAIGVPILVTPDREVLIPDLTEDVAETVVRVLAPL 301 Query 289 GLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNV----ESAGHRHFVGCERACGS 344 G +FD SPW+ SACTGSPGCA S ADVR D L + H+VGC+RACGS Sbjct 302 GFIFDATSPWVRTSACTGSPGCAKSLADVRTDLLDHLQTSGPADDGVREHWVGCDRACGS 361 Query 345 PPAGEV-LVATGGGYR 359 P VATG GYR Sbjct 362 PSGAHTRRVATGDGYR 377 >gi|72160722|ref|YP_288379.1| cobalamin biosynthesis protein CobG, precorrin-3B synthase [Thermobifida fusca YX] gi|71914454|gb|AAZ54356.1| cobalamin biosynthesis protein CobG, precorrin-3B synthase [Thermobifida fusca YX] Length=439 Score = 247 bits (631), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 159/381 (42%), Positives = 211/381 (56%), Gaps = 34/381 (8%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 D CPG LRPH AADGAL RIR+PGG I+ +ATL+ + + FG L LT+RGNVQ+RGI Sbjct 57 DRCPGVLRPHFAADGALLRIRIPGGHISRRGIATLSQITAKFGDGNLHLTSRGNVQIRGI 116 Query 68 --RDVAAVADA----VAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIR 121 D + + VA +G LPS+TH+RVRNIVASPLSG GG DVR V LD A+ Sbjct 117 PVTDDQQIPNELPHIVAASGFLPSSTHDRVRNIVASPLSGIIGGRMDVRPLVSALDRALC 176 Query 122 AEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTG--VRVADVAET 179 +PRLAEL GRF FGLDDGR D++G+ D+G+ + + G +G + ++ + Sbjct 177 TDPRLAELPGRFLFGLDDGRGDLAGMPIDLGIYAIDERSAQIRVGTFSGPVISSTEIVDI 236 Query 180 LIEVALRFVKIRETAWRVTELADIG-ELQSGVELGPSVRPVTKTPVGWIPQDDSR----- 233 ++++A RF+ I E W V +L G EL + VE +R TK+ W + R Sbjct 237 ILDLAHRFLDISEGKWNVVQLPKKGRELLNNVEFSNFLRH-TKSGDRWSVERFRRNILHG 295 Query 234 -VTLGAA-------VPLGVL-PARVAECLAAIE---APLVITPWRSVLICDLDDATADAA 281 +T+ A VPLGVL P L A E + +++TPWR V++ + A Sbjct 296 IITISTAESAVAGSVPLGVLTPPMQRALLDAAEHSDSTIILTPWRGVIVTPVPTDQASNV 355 Query 282 LRVLAPLGLVFDENSPWLNISACTGSPGCAHSAADVRADAARSL-------NVESAGHRH 334 +L GLV D SPW ISAC GSPGCA S D R+ A + + + H Sbjct 356 AALLQEAGLVLDPASPWSRISACIGSPGCARSRGDTRSQAVKLVRRLSSPDTSDDGSPYH 415 Query 335 FVGCERACGSPPAGEVLVATG 355 GCERACG+P LV G Sbjct 416 IAGCERACGAPHTPHTLVLLG 436 >gi|300788892|ref|YP_003769183.1| precorrin-3B synthase [Amycolatopsis mediterranei U32] gi|299798406|gb|ADJ48781.1| precorrin-3B synthase [Amycolatopsis mediterranei U32] Length=358 Score = 246 bits (628), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 170/357 (48%), Positives = 196/357 (55%), Gaps = 26/357 (7%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 ADACPG PH AADG LAR+RLPGG I+A QL LA A G L LT+RGNVQLRG Sbjct 9 ADACPGVFAPHDAADGPLARVRLPGGTISAVQLHALADAAEACGDGDLHLTSRGNVQLRG 68 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 + +A + AGLLPS +HERVRN++ASPLSG +GGLADVR LD + + P L Sbjct 69 VTR-PGLAARLTDAGLLPSPSHERVRNVLASPLSGVSGGLADVRGLAASLDLVLCSTPEL 127 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRV--ADVAETLIEV 183 A L GRF F DDGR DV+ GADV + LLL G DTG RV ADV LIEV Sbjct 128 AALPGRFLFAFDDGRGDVASEGADVCWRATGSSEGTLLLAGGDTGRRVARADVVAVLIEV 187 Query 184 ALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTLGAAVPLG 243 AL F ++R AWRV EL D + P R P G IPQD G G Sbjct 188 ALEFCRVRGAAWRVAELDDPAWRGT-----PVPRTGFSMPAGLIPQDGGGYAAGVVPRFG 242 Query 244 VLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENSPWLNISA 303 L A A LA LV TPW+S+++ D+ V A LG L +A Sbjct 243 QLSATQARALAEFGTALV-TPWKSLVLPDVPP-------DVFARLGF----GGEALGTTA 290 Query 304 CTGSPGCAHSAADVRADAARSLNVESAGHRHFVGCERACGSPPAGEV-LVATGGGYR 359 C G PGCA S ADVRADA + + HF GCER CG P V +VA GGYR Sbjct 291 CIGRPGCAKSRADVRADAVFRPGLRA----HFSGCERRCGKPSQSYVDVVAEAGGYR 343 >gi|284989174|ref|YP_003407728.1| precorrin-3B synthase [Geodermatophilus obscurus DSM 43160] gi|284062419|gb|ADB73357.1| precorrin-3B synthase [Geodermatophilus obscurus DSM 43160] Length=389 Score = 246 bits (627), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 183/376 (49%), Positives = 224/376 (60%), Gaps = 26/376 (6%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 ADACPGAL+ H AADGALAR+R+PGG++T QL +LA+ A D G LELT+RGNVQLRG Sbjct 13 ADACPGALQTHAAADGALARVRVPGGLLTGDQLRSLAAAARDLGDGALELTSRGNVQLRG 72 Query 67 IRDVAAVA--DAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 + AA D +A AGLLPSATHERVRN++AS L+GRAGG DVR WV LDAA+ A+P Sbjct 73 LAAGAAAELGDRLAAAGLLPSATHERVRNVLASALTGRAGGHVDVRPWVRALDAAVCADP 132 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVF-PDGPRLLLTGRDTGVRVADVAETLIEV 183 LA L GR+ LDDGR DV+GLG DVG+ P L L G D+G+R + + Sbjct 133 ALAALPGRYLATLDDGRGDVAGLGGDVGLLTLSPAEVALTLAGADSGLRAHPDDAVALAL 192 Query 184 ALRFVKIRE------TAWRVTELADIGELQSGVEL-------GPSVRPVTKTPVGWIPQD 230 A + E TAWR+ EL D G ++ G L PVG PQ Sbjct 193 AATRAFLAERTAQGGTAWRLAELDD-GAIRVGARLDGRRGVAVDVPPVPVPGPVGAAPQH 251 Query 231 DSRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGL 290 D RV L A VPLG L A AE LA + + +T WRS+++ DL + D A L G+ Sbjct 252 DGRVALVAVVPLGRLDAAQAELLARLADEVQLTSWRSIVVPDLAEDAVDDAAVALHRTGM 311 Query 291 VFDENSPWLNISACTGSPGCAHS-----AADVRADAARSLNVESAGHRHFVGCERACGSP 345 VFD SPW ++AC G PGCA S A A A +L V+ A +H+ GCER CG P Sbjct 312 VFDAASPWTRVTACAGRPGCAKSLADVRADAAAAVATGTLPVDGA-RQHWAGCERRCGRP 370 Query 346 PAGEV--LVATGGGYR 359 GEV +VATG GYR Sbjct 371 Q-GEVVDVVATGTGYR 385 >gi|38233819|ref|NP_939586.1| hypothetical protein DIP1231 [Corynebacterium diphtheriae NCTC 13129] gi|38200080|emb|CAE49758.1| Conserved hypothetical protein [Corynebacterium diphtheriae] Length=397 Score = 244 bits (624), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 146/369 (40%), Positives = 201/369 (55%), Gaps = 26/369 (7%) Query 7 ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRG 66 +D CPGAL+ H A DGA+ R+R PGG + A+Q +A ++ + G ++ +T RGN+Q RG Sbjct 30 SDMCPGALKLHHANDGAIGRVRFPGGRVRASQWEDIARISDELGDGSIHITTRGNMQFRG 89 Query 67 IRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEPRL 126 + D AA AD V AG LPS H+++RNI+ SPLS D +LD ++ + Sbjct 90 VSDEAAFADVVEAAGFLPSRRHDKIRNILCSPLSPELWTFTD------DLDQCLQENDVV 143 Query 127 AELGGRFWFGLDDGRADVSGLGADVGVQVFPDGP-RLLLTGRDTGVRVAD---VAETLIE 182 A L GR FG D G D+ D GV V+ DG +L+L G+ T V +AD VA L Sbjct 144 AGLSGRTLFGFDAGSGDIVSQNPDFGV-VYVDGAYQLILGGKTTSVAIADSDEVATILTA 202 Query 183 VALRFVKIRETAWRVTELADIGELQSGVELGPSVRPVTKT-----------PVGWIPQDD 231 A + +RE WR+ E + + + EL V + P+GWI DD Sbjct 203 AAEIWQNMREIEWRLHE-SPVARQRIAEELHERFDVVRREVAVPRAQGSARPIGWISADD 261 Query 232 SRVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLV 291 VTLGA + G L ++VA LAA+ ITPW S++I L + A+A +VLAP GL+ Sbjct 262 GTVTLGAGLRFGFLTSKVARILAAVGTDTSITPWASLVIHGLKEDEAEAVTKVLAPQGLI 321 Query 292 FDENSPWLNISACTGSPGCAHSAADVRADAARSLNV--ESAGHRHFVGCERACGSPPAGE 349 FD +SPWL ++ACTG PGC S + + DA + E G HF GC+R CG P + Sbjct 322 FDAHSPWLKVTACTGLPGCQKSLTNTQQDATTLVQSGDEINGLVHFSGCDRRCGHPLSHH 381 Query 350 V-LVATGGG 357 VA G G Sbjct 382 TEYVAVGDG 390 >gi|284032966|ref|YP_003382897.1| precorrin-3B synthase [Kribbella flavida DSM 17836] gi|283812259|gb|ADB34098.1| precorrin-3B synthase [Kribbella flavida DSM 17836] Length=396 Score = 243 bits (621), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 171/373 (46%), Positives = 218/373 (59%), Gaps = 26/373 (6%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 D CPG L HQAADG LAR+RLPGGM+TAAQL LA +++ G LELT+RGN+Q+R + Sbjct 10 DRCPGVLAVHQAADGGLARVRLPGGMLTAAQLRVLAVASAELGDGNLELTSRGNLQIRAL 69 Query 68 RDVA--AVADAVAKAGLLPSATHERVRNIVASPLSG-RAGGLADVRAWVGELDAAIRAEP 124 R A ++D + AGLLPS THERVRNI+ASPLSG L DV LD + P Sbjct 70 RPGAPKELSDRLYAAGLLPSITHERVRNILASPLSGLDTSSLYDVLPLAVALDQQLCGTP 129 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVF-PDGPRLLLTGRDTGVRV--ADVAETLI 181 RLAEL GRF F LDDGR D++ GADV V++ D L+L G DTGVRV AD T++ Sbjct 130 RLAELPGRFLFALDDGRGDLATSGADVAVRMLAADQAALVLAGTDTGVRVAPADAPSTML 189 Query 182 EVALRFVKIRE----TAWRVTELAD-----IGELQSGVELGPSVRPVTKTPVGWIPQDDS 232 A F+ RE +AWR+ EL + + +L++ ++ P + P G Q + Sbjct 190 RAAEAFLDEREAQHSSAWRLAELENGADAVLAQLRAALQ-HSPASPSSSLPTGKAVQVGT 248 Query 233 RVT---LGAAVPLGVL-PARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPL 288 R++ L VPLG L PA+ A + A E L +TPWRSV++ A R L Sbjct 249 RLSGNGLVVGVPLGSLSPAQAAALMEAEE--LRVTPWRSVVMVGAKTPAALVEAR-LTQA 305 Query 289 GLVFDENSPWLNISACTGSPGCAHSAADVRADAARSLNVESAGHR--HFVGCERACGSPP 346 GLV D SPW ++AC G PGC + ADVRADA R + A HR H+ GCER CG P Sbjct 306 GLVVDPESPWNRVTACAGRPGCGKALADVRADARRVTAMMPARHRPVHWSGCERRCGQPT 365 Query 347 AGEV-LVATGGGY 358 V ++A GY Sbjct 366 GDFVDVLAVADGY 378 >gi|289443567|ref|ZP_06433311.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T46] gi|289416486|gb|EFD13726.1| cobalamin biosynthesis protein cobG [Mycobacterium tuberculosis T46] Length=161 Score = 241 bits (616), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 129/130 (99%), Positives = 130/130 (100%), Gaps = 0/130 (0%) Query 1 VAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 +AGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG Sbjct 1 MAGTRDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARG 60 Query 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI Sbjct 61 NVQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAI 120 Query 121 RAEPRLAELG 130 RAEPRLAELG Sbjct 121 RAEPRLAELG 130 >gi|227488955|ref|ZP_03919271.1| precorrin-3B synthase [Corynebacterium glucuronolyticum ATCC 51867] gi|227542052|ref|ZP_03972101.1| precorrin-3B synthase [Corynebacterium glucuronolyticum ATCC 51866] gi|227091031|gb|EEI26343.1| precorrin-3B synthase [Corynebacterium glucuronolyticum ATCC 51867] gi|227182200|gb|EEI63172.1| precorrin-3B synthase [Corynebacterium glucuronolyticum ATCC 51866] Length=388 Score = 240 bits (613), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 146/368 (40%), Positives = 209/368 (57%), Gaps = 20/368 (5%) Query 3 GTRD-ADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGN 61 G RD +D CPGA + H A DGA+ R+R+ GG +T A LA++A D G + +T RGN Sbjct 17 GDRDRSDGCPGAQKMHHANDGAIGRVRVAGGHLTPAGWKALAAMARDLGDGDIHMTTRGN 76 Query 62 VQLRGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIR 121 +Q+RGI D V +G LPS H++VRNI+ASP+ G +AD+ V ELD A+ Sbjct 77 LQIRGISDEDTFTQEVISSGFLPSRAHDKVRNIIASPMDGE---IADL---VRELDRALL 130 Query 122 AEPRLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVA--DVAET 179 A ++ L GR FGLDDG A + D G D L+L G TGV++ VA + Sbjct 131 ASEKVTGLSGRTLFGLDDGSATIFAHEVDFGAIRVNDVFYLVLGGTLTGVQMNHDQVAAS 190 Query 180 LIEVALRFVKIRETAWRVTE-------LADIGELQSGVELGPSVRPVTKTPVGWIPQDDS 232 ++ +A ++ +IR AWRV E L + + + P++ P P+GWI ++ Sbjct 191 IVAIAEKWQEIRSDAWRVKERPEKRNDLIRVLDGEVTFTAPPNIPPSHDRPIGWIDGENG 250 Query 233 RVTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVF 292 VTL AV GV+PA +A+ +AA +TPW ++I +A A+ A++ LAP+G++F Sbjct 251 -VTLVGAVRFGVVPADLADLIAATGKKSTVTPWHRIVIHGFTEAEAEEAVKRLAPVGMIF 309 Query 293 DENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAGEV 350 D +SPWL ++ACTG P C ++ R DA + + SA G HFVGCER CG P Sbjct 310 DADSPWLRVTACTGLPECQKGKSNTRRDAIQLVESGSAPEGLVHFVGCERRCGHPLEDHT 369 Query 351 -LVATGGG 357 +ATG G Sbjct 370 EYLATGDG 377 >gi|296139897|ref|YP_003647140.1| precorrin-3B synthase [Tsukamurella paurometabola DSM 20162] gi|296028031|gb|ADG78801.1| precorrin-3B synthase [Tsukamurella paurometabola DSM 20162] Length=351 Score = 237 bits (604), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 168/357 (48%), Positives = 209/357 (59%), Gaps = 27/357 (7%) Query 5 RDADACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQL 64 R D CPG LRPH AADGAL R+RLPGG +TAAQL LA +A +ELT+RGNVQ+ Sbjct 5 RQPDNCPGVLRPHAAADGALVRVRLPGGRLTAAQLEVLAELAD---GGDIELTSRGNVQV 61 Query 65 RGIRDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAWVGELDAAIRAEP 124 RG+RD+ A A++ AGLLPS+THERVRNIVASPL+ +D A Sbjct 62 RGVRDLDAARAALSAAGLLPSSTHERVRNIVASPLA-HPQAARAAELDAALIDRAA---- 116 Query 125 RLAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRVADVAETLIEVA 184 LA L GRF F DDG D++ L ADV + DG L L G T + E +++ A Sbjct 117 -LAALPGRFLFAFDDGSGDIASLIADVESR---DG-VLHLDGHSTDL--PGTTEMMLDAA 169 Query 185 LRFVKIRETAWRVTELAD--------IGELQSGVELGPSVRPVTKTPVGWIPQDDSRVTL 236 F+ +R WR+ +LAD +G +G E+ V PVGW ++D V L Sbjct 170 QAFLDLRADEWRIRDLADGAARVAAALGGTVTGREVPDGV---PAPPVGWFDREDGTVAL 226 Query 237 GAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFDENS 296 GA V LG LPAR A LAAIE P+ ITPWR++L+ DLD+ A+ +RVLAP+GL+FD S Sbjct 227 GAGVSLGRLPARTALFLAAIERPITITPWRTLLVHDLDEDAAETVVRVLAPMGLIFDAGS 286 Query 297 PWLNISACTGSPGCAHSAADVRADAARSLNVESAGHR-HFVGCERACGSPPAGEVLV 352 PWL +SAC G GCA + AD A AA A R H V C R CG+PP LV Sbjct 287 PWLRVSACVGDRGCARAEADALAHAAELAGELGADERIHVVACSRGCGAPPGEHRLV 343 >gi|225021474|ref|ZP_03710666.1| hypothetical protein CORMATOL_01494 [Corynebacterium matruchotii ATCC 33806] gi|224945856|gb|EEG27065.1| hypothetical protein CORMATOL_01494 [Corynebacterium matruchotii ATCC 33806] Length=383 Score = 236 bits (601), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 152/369 (42%), Positives = 201/369 (55%), Gaps = 26/369 (7%) Query 8 DACPGALRPHQAADGALARIRLPGGMITAAQLATLASVASDFGSATLELTARGNVQLRGI 67 D CPGA + H A DG++ R+R PGG + Q A +A +A++ G + +T RGN+Q RG+ Sbjct 17 DICPGAFKLHHATDGSIGRVRFPGGHVRPQQWADIARIATELGDGNIHVTTRGNMQFRGV 76 Query 68 RDVAAVADAVAKAGLLPSATHERVRNIVASPLSGRAGGLADVRAW--VGELDAAIRAEPR 125 V +AG +PS H+++RNI+ASPLS + W V LDAA+ A Sbjct 77 TQDQEFGCVVTQAGFVPSQPHDKIRNIIASPLS--------LELWPLVDALDAALLATDA 128 Query 126 LAELGGRFWFGLDDGRADVSGLGADVGVQVFPDGPRLLLTGRDTGVRV--ADVAETLIEV 183 A L GR FGLD G + D + D +L+L G V V ADV E L Sbjct 129 TAGLSGRTLFGLDAGDGAIISQEPDFAARKVGDRYQLVLGGAPQHVTVSEADVPEVLAFA 188 Query 184 ALRFVKIRETAWRVTE--------LADIGELQSGVELG--PSVRPVTKTPVGWIPQDDSR 233 A + R AWR+ E LADI E + +L P+V T P+GWI D+ R Sbjct 189 AAWWQAHRGDAWRLHETPEDISLILADIAEAFAVDKLDELPTVPETTAAPIGWIDNDNGR 248 Query 234 VTLGAAVPLGVLPARVAECLAAIEAPLVITPWRSVLICDLDDATADAALRVLAPLGLVFD 293 VTLGA + G PA VA LA + A ITPW S++I DLD++ A+AA++ LAPLGL+FD Sbjct 249 VTLGAGLRFGFFPASVAAMLATLGAETTITPWASLVIHDLDESHAEAAIKALAPLGLIFD 308 Query 294 ENSPWLNISACTGSPGCAHSAADVRADAARSLNVESA--GHRHFVGCERACGSPPAG--E 349 +SPWL I+ACTG PGCA S + DA +N ++ G HF GC+R CG P E Sbjct 309 ADSPWLRITACTGLPGCAKSKSHTHDDAVALMNSDNIPDGLVHFSGCDRRCGHPRVAHTE 368 Query 350 VLVATGGGY 358 L G Y Sbjct 369 YLAVAEGEY 377 Lambda K H 0.320 0.136 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 682094012100 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40